Guide to the Human Genome
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Name: HMGB1 Sequence: fasta or formatted (215aa) NCBI GI: 4504425
Description:

high-mobility group box 1

Referenced in:

Nonhistone Chromosomal Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.8         19           2
 C cysteine            1.4          3           1
 D aspartate           9.3         20           4
 E glutamate          16.7         36           5
 F phenylalanine       4.2          9           2
 G glycine             5.1         11           1
 H histidine           1.4          3           1
 I isoleucine          1.9          4           1
 K lysine             20.0         43           4
 L leucine             1.9          4           1
 M methionine          2.8          6           1
 N asparagine          1.9          4           2
 P proline             6.0         13           2
 Q glutamine           0.9          2           1
 R arginine            3.7          8           1
 S serine              5.1         11           2
 T threonine           2.3          5           1
 V valine              2.3          5           2
 W tryptophan          0.9          2           1
 Y tyrosine            3.3          7           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   high-mobility group box 1 
HMGB1L1               0.917   high-mobility group box 1-like 1 
HMGB2                 0.799   high-mobility group box 2 
HMGB2                 0.799   high-mobility group box 2 
HMGB2                 0.799   high-mobility group box 2 
LOC645490             0.720   PREDICTED: similar to hCG1991922 
LOC645490             0.720   PREDICTED: similar to hCG1991922 
LOC645490             0.704   PREDICTED: similar to hCG1991922 
SP100                 0.701   nuclear antigen Sp100 isoform 2 
HMGB3                 0.678   high-mobility group box 3 
LOC646993             0.611   PREDICTED: similar to high mobility group box 3 [Ho...
LOC646993             0.611   PREDICTED: similar to high mobility group box 3 [Ho...
LOC646993             0.611   PREDICTED: similar to high mobility group box 3 [Ho...
LOC441795             0.576   PREDICTED: high mobility group protein B3-like prot...
LOC441795             0.576   PREDICTED: high mobility group protein B3-like prot...
LOC203510             0.555   PREDICTED: similar to hCG1644442 
LOC203510             0.555   PREDICTED: similar to hCG1644442 
LOC203510             0.555   PREDICTED: hypothetical protein LOC203510 
LOC729595             0.536   PREDICTED: similar to high mobility group box 3 [Ho...
LOC729595             0.536   PREDICTED: similar to high mobility group box 3 [Ho...
LOC729595             0.536   PREDICTED: similar to high mobility group box 3 iso...
LOC644129             0.405   PREDICTED: similar to hCG1647425 
LOC644129             0.405   PREDICTED: similar to hCG1647425 
LOC729595             0.400   PREDICTED: similar to high mobility group box 3 iso...
LOC644129             0.339   PREDICTED: similar to hCG1647425 
HMGB4                 0.299   HMG2 like isoform 1 
SSRP1                 0.161   structure specific recognition protein 1 
UBTF                  0.133   upstream binding transcription factor, RNA polymera...
UBTF                  0.133   upstream binding transcription factor, RNA polymera...
UBTF                  0.133   upstream binding transcription factor, RNA polymerase...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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