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Search of human proteins with 7662228
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo
sapiens]
(907 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo ... 1784 0.0
gi|56788366 phosphatidylinositol-binding clathrin assembly prote... 509 e-144
gi|56788368 phosphatidylinositol-binding clathrin assembly prote... 504 e-142
gi|163965366 nascent polypeptide-associated complex alpha subuni... 117 6e-26
gi|33946327 nucleoporin 214kDa [Homo sapiens] 98 4e-20
gi|91982772 mucin 17 [Homo sapiens] 98 4e-20
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] 97 7e-20
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 94 4e-19
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 92 3e-18
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ... 92 3e-18
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 91 5e-18
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens] 91 5e-18
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 91 6e-18
gi|116284392 mucin 2 precursor [Homo sapiens] 90 1e-17
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 84 8e-16
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 83 1e-15
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 82 2e-15
gi|47132519 Ras association and pleckstrin homology domains 1 is... 82 2e-15
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 81 5e-15
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 81 5e-15
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 81 5e-15
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 81 5e-15
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 81 5e-15
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 80 1e-14
gi|161019170 mucin 5AC [Homo sapiens] 76 1e-13
gi|110832843 TBP-associated factor 4 [Homo sapiens] 75 3e-13
gi|167736355 mucin 4 isoform a [Homo sapiens] 75 3e-13
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 75 4e-13
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi... 74 8e-13
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 73 1e-12
>gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo
sapiens]
Length = 907
Score = 1784 bits (4621), Expect = 0.0
Identities = 907/907 (100%), Positives = 907/907 (100%)
Query: 1 MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMA 60
MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMA
Sbjct: 1 MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMA 60
Query: 61 DTLFERATNSSWVVVFKALVTTHHLMVHGNERFIQYLASRNTLFNLSNFLDKSGSHGYDM 120
DTLFERATNSSWVVVFKALVTTHHLMVHGNERFIQYLASRNTLFNLSNFLDKSGSHGYDM
Sbjct: 61 DTLFERATNSSWVVVFKALVTTHHLMVHGNERFIQYLASRNTLFNLSNFLDKSGSHGYDM 120
Query: 121 STFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMAPEKLLKSMPILQGQIDALLE 180
STFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMAPEKLLKSMPILQGQIDALLE
Sbjct: 121 STFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMAPEKLLKSMPILQGQIDALLE 180
Query: 181 FDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRF 240
FDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRF
Sbjct: 181 FDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRF 240
Query: 241 LTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPS 300
LTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPS
Sbjct: 241 LTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPS 300
Query: 301 PLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGG 360
PLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGG
Sbjct: 301 PLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGG 360
Query: 361 AAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA 420
AAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA
Sbjct: 361 AAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA 420
Query: 421 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF 480
SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF
Sbjct: 421 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF 480
Query: 481 APSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAAT 540
APSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAAT
Sbjct: 481 APSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAAT 540
Query: 541 AAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQG 600
AAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQG
Sbjct: 541 AAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQG 600
Query: 601 ASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAA 660
ASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAA
Sbjct: 601 ASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAA 660
Query: 661 SSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDG 720
SSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDG
Sbjct: 661 SSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDG 720
Query: 721 LGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDL 780
LGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDL
Sbjct: 721 LGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDL 780
Query: 781 QWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGF 840
QWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGF
Sbjct: 781 QWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGF 840
Query: 841 GMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDPLAD 900
GMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDPLAD
Sbjct: 841 GMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDPLAD 900
Query: 901 LNIKDFL 907
LNIKDFL
Sbjct: 901 LNIKDFL 907
>gi|56788366 phosphatidylinositol-binding clathrin assembly protein
isoform 1 [Homo sapiens]
Length = 652
Score = 509 bits (1310), Expect = e-144
Identities = 285/504 (56%), Positives = 348/504 (69%), Gaps = 67/504 (13%)
Query: 1 MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMA 60
MSGQ+LTDRI AAQ+SVTGSAV++ VCKATTHE+MGPKKKHLDYLIQ TNE NVNIPQ+A
Sbjct: 1 MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA 60
Query: 61 DTLFERATNSSWVVVFKALVTTHHLMVHGNERFIQYLASRNTLFNLSNFLDKSGSHGYDM 120
D+LFER TNSSWVVVFK+L+TTHHLMV+GNERFIQYLASRNTLFNLSNFLDKSG GYDM
Sbjct: 61 DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM 120
Query: 121 STFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMAPEKLLKSMPILQGQIDALLE 180
STFIRRYSRYLNEKA SYRQ+AFDF +VK+GADGVMRTM EKLLK++PI+Q Q+DALL+
Sbjct: 121 STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD 180
Query: 181 FDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRF 240
F+V+ NELTNGVINAAFMLLFKD I+LFA YN+G+INLLEK+F+MKK QCK+ L+IYK+F
Sbjct: 181 FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF 240
Query: 241 LTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPS 300
LTRMTR+SEFLKVAEQVGID+GDIPDL+QAPSSL++ LEQHL +LEGKK ++ + +
Sbjct: 241 LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRAT 300
Query: 301 PLSKS----------------------------------------------SPATTVTSP 314
LS + + TT SP
Sbjct: 301 TLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASP 360
Query: 315 NSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDL-QPDFSSGGAAAAAAPAPPPPA 373
ST A I T+P +D+F+T S++ STSK +DLLDL QP F + A +
Sbjct: 361 VSTSAGGIMTAPAIDIFSTPSSS--NSTSKLPNDLLDLQQPTFHPSVHPMSTA------S 412
Query: 374 GGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAV 433
A+ WGD A ++PS +PF + ++ ++ + +S +T T
Sbjct: 413 QVASTWGDPFSATVDAVDDAIPS----LNPFLTK-----SSGDVHLSISSDVSTFTTRTP 463
Query: 434 TAEVDLFGDAFAASPGEAPAASEG 457
T E+ + F SP P S G
Sbjct: 464 THEMFV---GFTPSPVAQPHPSAG 484
Score = 144 bits (364), Expect = 3e-34
Identities = 117/346 (33%), Positives = 167/346 (48%), Gaps = 52/346 (15%)
Query: 537 TAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSS 596
T+ T AA+ +T++ T PA+DIF STP + + +DL S
Sbjct: 352 TSLTTAASPVSTSAGGIMTA--PAIDIF-----STPSSSNSTSKLPNDLLDLQQPTFHPS 404
Query: 597 PPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPA 656
++ +S D S A + +P SSG + L + S S
Sbjct: 405 VHPMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHL---SISSDVS----- 456
Query: 657 SQAASSSSASADLLAGFGGSFMAPSPSPVT-PAQNNLLQPNFEAAFGTTPSTSSSSSFDP 715
++ + + ++ GF +PSPV P + L +FE+ FG + S++ D
Sbjct: 457 --TFTTRTPTHEMFVGF-------TPSPVAQPHPSAGLNVDFESVFG---NKSTNVIVDS 504
Query: 716 SVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTT 775
FD LG LL PT+A Q PV+ +PPS K + DLDSSLA+LVGNLGI TT
Sbjct: 505 GGFDELGGLLKPTVASQNQNLPVAKLPPS------KLVSDDLDSSLANLVGNLGIGNGTT 558
Query: 776 KKGDLQWNA-GEKKLTGGANWQPKVAPAT-WSAGVPPSAPLQGAVPPTSSVPPVAGAPSV 833
K D+ W+ GEKKLTGG+NWQPKVAP T W+A + PPV P+
Sbjct: 559 KN-DVNWSQPGEKKLTGGSNWQPKVAPTTAWNA--------------ATMAPPVMAYPAT 603
Query: 834 GQPG-AGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQL 878
G G+G+PP +P+M Q ++++QP+MRPP V G Q+
Sbjct: 604 TPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQI 649
>gi|56788368 phosphatidylinositol-binding clathrin assembly protein
isoform 2 [Homo sapiens]
Length = 610
Score = 504 bits (1297), Expect = e-142
Identities = 270/436 (61%), Positives = 320/436 (73%), Gaps = 63/436 (14%)
Query: 1 MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMA 60
MSGQ+LTDRI AAQ+SVTGSAV++ VCKATTHE+MGPKKKHLDYLIQ TNE NVNIPQ+A
Sbjct: 1 MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA 60
Query: 61 DTLFERATNSSWVVVFKALVTTHHLMVHGNERFIQYLASRNTLFNLSNFLDKSGSHGYDM 120
D+LFER TNSSWVVVFK+L+TTHHLMV+GNERFIQYLASRNTLFNLSNFLDKSG GYDM
Sbjct: 61 DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM 120
Query: 121 STFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMAPEKLLKSMPILQGQIDALLE 180
STFIRRYSRYLNEKA SYRQ+AFDF +VK+GADGVMRTM EKLLK++PI+Q Q+DALL+
Sbjct: 121 STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD 180
Query: 181 FDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRF 240
F+V+ NELTNGVINAAFMLLFKD I+LFA YN+G+INLLEK+F+MKK QCK+ L+IYK+F
Sbjct: 181 FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF 240
Query: 241 LTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPS 300
LTRMTR+SEFLKVAEQVGID+GDIPDL+QAPSSL++ LEQHL +LEGKK ++ + +
Sbjct: 241 LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRAT 300
Query: 301 PLSKS----------------------------------------------SPATTVTSP 314
LS + + TT SP
Sbjct: 301 TLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASP 360
Query: 315 NSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDL-QPDF--------------SSG 359
ST A I T+P +D+F+T S++ STSK +DLLDL QP F S+
Sbjct: 361 VSTSAGGIMTAPAIDIFSTPSSS--NSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTW 418
Query: 360 GAAAAAAPAPPPPAGG 375
G + A P P+ G
Sbjct: 419 GGFTPSPVAQPHPSAG 434
Score = 149 bits (376), Expect = 1e-35
Identities = 126/350 (36%), Positives = 175/350 (50%), Gaps = 46/350 (13%)
Query: 540 TAAATTTTTTSAATATTAPPALDIFG----DLFESTPEVAAAPKPDAAPSIDLFSTDAFS 595
+ AA+ TT S A ++ A L + + + E A K + + +
Sbjct: 293 STAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHT 352
Query: 596 SPPQGASPVPESS---LTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASE 652
S ASPV S+ +TA ++D F+ PS + + S D ++DL F S
Sbjct: 353 SLTTAASPVSTSAGGIMTAP--AIDIFSTPSSSNSTSKLPND---LLDLQQPTFHPSVHP 407
Query: 653 PQPASQAASSSSASADLLAGFGGSFMAPSPSPVT-PAQNNLLQPNFEAAFGTTPSTSSSS 711
ASQ AS+ +GG +PSPV P + L +FE+ FG + S++
Sbjct: 408 MSTASQVAST----------WGGF----TPSPVAQPHPSAGLNVDFESVFG---NKSTNV 450
Query: 712 SFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGIS 771
D FD LG LL PT+A Q PV+ +PPS K + DLDSSLA+LVGNLGI
Sbjct: 451 IVDSGGFDELGGLLKPTVASQNQNLPVAKLPPS------KLVSDDLDSSLANLVGNLGIG 504
Query: 772 GTTTKKGDLQWNA-GEKKLTGGANWQPKVAPAT-WSAGVPPSAPLQGAVPPTSSVPPVAG 829
TTK D+ W+ GEKKLTGG+NWQPKVAP T W+A A + G P PPV
Sbjct: 505 NGTTKN-DVNWSQPGEKKLTGGSNWQPKVAPTTAWNA-----ATMNGMHFP-QYAPPVMA 557
Query: 830 APSVGQPG-AGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQL 878
P+ G G+G+PP +P+M Q ++++QP+MRPP V G Q+
Sbjct: 558 YPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQI 607
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 117 bits (292), Expect = 6e-26
Identities = 181/692 (26%), Positives = 239/692 (34%), Gaps = 128/692 (18%)
Query: 298 APSPLSKSSPATT----------VTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSS 347
APSP + +P T V SP+ PA T + VD + SA PV++S
Sbjct: 711 APSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKEC 770
Query: 348 DLLD--LQPDFSSGGAAAAAAPAPPP-----------------PAGGATAWGDL------ 382
D SS G A +P P AG T G+L
Sbjct: 771 PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSP 830
Query: 383 -----LGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASAST-----TTTVTA 432
L E+SL+ S S A P P P T + + S T T T +
Sbjct: 831 VEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSV 890
Query: 433 VTAEVDLFGDAFAASPGEAPAASEGAAAP----ATPTPVAAALDACSGNDPFAPSEGSAE 488
V G A A P +APA S +++P ATP P P +PS A
Sbjct: 891 VNLPFPKEGPATPA-PKQAPALSMTSSSPKKARATPAPKGI---------PASPSPKGAP 940
Query: 489 AAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTT 548
P A PP TP+ AP PA P A + A T A T +
Sbjct: 941 TPP-----AATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPS 995
Query: 549 TSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESS 608
AT +P TP P P +P+ F A S+PP P P+ S
Sbjct: 996 PKGGPATPSPKGAP--------TPPAVTPPSPKGSPAATPFPKGA-STPPAATPPSPKGS 1046
Query: 609 LTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASAD 668
A L A P+ AT SP L G +A+ P P A+ S A
Sbjct: 1047 PAATPLPKGAPTTPA-ATLPSPK--GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP 1103
Query: 669 LLAGF------GGSFMAPSP-SPVTPAQNNLLQPNFEAAFGTTP---STSSSSSFDPSVF 718
+ GG P +P TPA P+ + T P + ++ ++ PS
Sbjct: 1104 MPPAATPPSPKGGLATPPHKGAPTTPAAT---PPSPKGGLATPPPKGAPTTPAATPPSPK 1160
Query: 719 DGLGDLLMPTMAPAGQPAPVSMVPPSP--AMAASKALGSDLDSSLASLVGNLGISGTTTK 776
GL T P G P + PPSP +A G+ + G++ + K
Sbjct: 1161 GGLA-----TPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1215
Query: 777 KGDLQWNAGEKKLTGG-ANWQPKVAPATWSA------GVPPSAPLQGAVPPTSSVPP--- 826
A GG A PK AP T +A G P + P +GA P ++ PP
Sbjct: 1216 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLK 1275
Query: 827 --VAGAPSVGQP-----------GAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAV 873
+A P G P G PP G P P P PP GA
Sbjct: 1276 GGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP 1335
Query: 874 P--------GTQLSPSPTPASQ-SPKKPPAKD 896
P GT P+ TP+S+ P P +K+
Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKE 1367
Score = 95.5 bits (236), Expect = 2e-19
Identities = 147/656 (22%), Positives = 219/656 (33%), Gaps = 86/656 (13%)
Query: 290 PGNNEGSGAPSPLSKSSPAT---TVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSK-P 345
P + +GS A +PL K +P T T+ SP PA +P + T AA P S P
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPA-----TPSLKGAPTPPAATPPSPKGGP 1094
Query: 346 SSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDP-- 403
++ S GA A PP P GG + AA P + P
Sbjct: 1095 ATP--------SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPK 1146
Query: 404 ---FAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAA 460
P TPP+ +AT + TT + G SP AP AA
Sbjct: 1147 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK---GGLATPSPKGAPTTP--AAT 1201
Query: 461 PATP-----TPVAAALDACSGNDPFAPSEGSAEAAPE--LDLFAMKPPETSVPVVTPTAS 513
P +P TP P +P G A +P+ A PP TP
Sbjct: 1202 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPK 1261
Query: 514 TAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPE 573
AP PA P A A A T + AT+ P TP
Sbjct: 1262 GAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP--------TPP 1313
Query: 574 VAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKV 633
A P P +P +PP P P+ + T + + P+ ++
Sbjct: 1314 AATPPSPKGSPGTP--PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP 1371
Query: 634 DSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTP------ 687
++ G A + + PA + S ++ ++P +P TP
Sbjct: 1372 PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIP------LSPKKAPATPVTREGA 1425
Query: 688 ---AQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPS 744
++ +L P +S+ P+ GD +P + P P+P PP+
Sbjct: 1426 ATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP---PSPKE--PPA 1480
Query: 745 PAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATW 804
P A+ + ++ A + G T + + E T + P AT
Sbjct: 1481 PKQVATSSSPKKAPATPAPM-------GAPTLPAVIPSSPKEVPATPSSRRDPIAPTATL 1533
Query: 805 SAGVPPS--APLQGAVPPTSSVPPVAGAPSVGQPGAG--------FGMPPAGTGMPMM-- 852
+ P+ AP + +PP +VP P++ P PPA T
Sbjct: 1534 LSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGA 1593
Query: 853 PQQPVMFAQPMMRPPFGAAA-VPGTQLSPSPT--PASQSPKKPPAKDPLADLNIKD 905
P + P + P A P PSP PA+ +PK P P+ ++KD
Sbjct: 1594 PSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKD 1649
Score = 87.4 bits (215), Expect = 5e-17
Identities = 151/641 (23%), Positives = 226/641 (35%), Gaps = 125/641 (19%)
Query: 290 PGNNEGSGAPSP--LSKSSPATTVTSPNSTPA-KTIDTSPPVDLFATASAAVPVSTSKPS 346
PG GAP+P ++ SP T T P +TP+ K T+P T AA P P+
Sbjct: 1324 PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPA 1383
Query: 347 SDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSV-------PSEAQ 399
+ P G PA P P G T+ + A + V PS+
Sbjct: 1384 -----MTPPSPKRG------PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432
Query: 400 ISDPFAP----EPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAAS 455
++ P + P T+ + A+ S+ T+ AVT SP E PA
Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPP----------SPKEPPAPK 1482
Query: 456 EGAA------APATPTPVAA-----ALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETS 504
+ A APATP P+ A + + P PS AP L + K P T
Sbjct: 1483 QVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL 1542
Query: 505 VP--VVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTA----P 558
P + P A T P T P P A A ++ A++ T +T + P
Sbjct: 1543 APKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIP 1602
Query: 559 PALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDA 618
PA+ TP P P+ P A+P P+ + T+ ++ +
Sbjct: 1603 PAVTSPSPKEAPTPPAVTPPSPEKGP----------------ATPAPKGTPTSPPVTPSS 1646
Query: 619 FAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFM 678
SP SPA V G++ + A +A ++L +
Sbjct: 1647 L-KDSP---TSPASVTCK---------MGATVPQASKGLPAKKGPTALKEVL-------V 1686
Query: 679 APSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPV 738
AP+P P A P T SS+ P + A G P+
Sbjct: 1687 APAPEST---------PIITAPTRKGPQTKKSSATSPPI-------CPDPSAKNGSKGPL 1730
Query: 739 SMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDL--QWNAGEKKLTGGA--N 794
S V P+P + K DSS + G + + KG L + LT A
Sbjct: 1731 STVAPAPLLPVQK------DSSKTA----KGKDASHSPKGPLAPPESKASTPLTAAAFEK 1780
Query: 795 WQPKVAPATWSAGVPPSAPLQGAVPPTSSVPP----VAGAPSVGQPGAGFGMPPAGTG-- 848
PK A+ SA P L A P ++PP + +P + + PA
Sbjct: 1781 VLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDEL 1840
Query: 849 MPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSP 889
+P++P +P+ P + P + P PTP+++ P
Sbjct: 1841 LPLIPPEPISGGVP-FQSVLVNMPTPKSAGIPVPTPSAKQP 1880
Score = 85.1 bits (209), Expect = 3e-16
Identities = 181/719 (25%), Positives = 245/719 (34%), Gaps = 147/719 (20%)
Query: 297 GAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDF 356
G +P K +P T +P S P + T PP T +A P P L P
Sbjct: 1116 GLATPPHKGAPTTPAATPPS-PKGGLATPPPKGAPTTPAATPP----SPKGGLATPPPK- 1169
Query: 357 SSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISD-----PFAPEPTPP 411
GA A PP P GG + AA P + P P TPP
Sbjct: 1170 ---GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1226
Query: 412 TTTAEIATASASASTTTTVTAVTAEVDLFGDAF-----AASPGEA--PAASEGAAAP--- 461
+ +AT S + TT A T G A A +P A P+ G A P
Sbjct: 1227 SPKGGLATPSPKGAPTTP--AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK 1284
Query: 462 ATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPAT 521
P P + G +P +G A P A PP TP AP PA
Sbjct: 1285 GAPNPAVVTPPSPKGGPATSPPKG-APTPP-----AATPPSPKGSPGTPPPKGAPTPPAV 1338
Query: 522 APSPAPAVAAAAAATTAATAAATTT------TTTSAATAT-------------------- 555
P P+P ATT ++ TT T AAT +
Sbjct: 1339 TP-PSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPS 1397
Query: 556 -----TAPPALDIFGDLFESTP---EVAAAPK-----PDAAPSIDLFSTDAFSSPPQG-A 601
T+P + + +TP E AA P P A + L A S+P G A
Sbjct: 1398 PKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPA 1457
Query: 602 SPVPESSLTADLLSVDAFAAPSP---------ATTASPAKVDSS----GVIDLFGDAFGS 648
+P + T + A PSP AT++SP K ++ G L S
Sbjct: 1458 TPSSKGDPT-----LPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSS 1512
Query: 649 SASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGT----- 703
P S + +A LL+ + +AP + + PA + P A T
Sbjct: 1513 PKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAM-TVPSPKKTPAIPTPKEAP 1571
Query: 704 -TPSTSSSSS---FDPSVFDGL---GDLLMP----TMAPAGQPAPVSMVPPS----PAMA 748
TPS+ +SS PS + G +LL+P + +P P P ++ PPS PA
Sbjct: 1572 ATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATP 1631
Query: 749 ASKALGS----------DLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPK 798
A K + D +S AS+ +G + KG L G L +
Sbjct: 1632 APKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKG-LPAKKGPTALK-----EVL 1685
Query: 799 VAPATWSAGVPPSAPLQGAVPPTSSV--PPVAGAPSV--GQPGAGFGMPPA--------- 845
VAPA S + + +G SS PP+ PS G G + PA
Sbjct: 1686 VAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDS 1745
Query: 846 -----GTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDPLA 899
G P+ P+ + P AAA P S +P PP PLA
Sbjct: 1746 SKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAP-SPPVSLPLA 1803
Score = 79.3 bits (194), Expect = 1e-14
Identities = 153/649 (23%), Positives = 233/649 (35%), Gaps = 85/649 (13%)
Query: 300 SPLSKSSPATTVTSPNSTPAKTIDTSPPV------DLFATASAAV---PVSTSKPSSDLL 350
+PL ++P T +P +T SPP+ ++ T+ AA+ PV+ +PS+ +
Sbjct: 439 TPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQV- 497
Query: 351 DLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTP 410
++ + P P P L+ + L +VP+ + PF+P
Sbjct: 498 ------ATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLE-GAPFSPAQAG 550
Query: 411 PTTTAE-----IATASASASTTTTVTAVTAEVDLFGDAFAA--SPGEAPAASEGAAAPAT 463
TT + + A+ S + T+ + E+ L +A A S GE + A++ +
Sbjct: 551 LTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTS 610
Query: 464 PTPVAAAL-----DACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPV-VTPTASTAPP 517
P V ++ D+ +G D P S+ P + F P E++ P V PT +
Sbjct: 611 PLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAF---PLESADPAGVAPTTAKGTS 667
Query: 518 VPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAA 577
T SP + A T TT TA+ P + + A
Sbjct: 668 TYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLA 727
Query: 578 PK-PDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPAT-TASPAKVDS 635
P+ P + PS L + P G V S T+ L V + P + + A S
Sbjct: 728 PEIPKSVPSPSLPP----AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASS 783
Query: 636 SGVIDLFGDA---FGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNL 692
G + D+ G S S PQ SA D G SPV+P + +
Sbjct: 784 KGTLTYLADSPSPLGVSVS-PQTKRPPTKKGSAGPDTPIG-------NLSSPVSPVEASF 835
Query: 693 LQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPT-MAPAGQPAPVSMVP--------- 742
L N + G+ S +++ S P G T ++P G P P
Sbjct: 836 LPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPF 895
Query: 743 -------PSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANW 795
P+P A + ++ S + GI + + KG A
Sbjct: 896 PKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPP------- 948
Query: 796 QPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQ 855
PK PAT S P+ P A PP+ P +P G P PP+ G P P
Sbjct: 949 SPKGGPATPSPKWAPTPP--AATPPSPKGGPATPSPK-GAPTPPAATPPSPKGGPATPSP 1005
Query: 856 PVMFAQPMMRPPF---GAAAVP---GTQLSPSPTPASQSPKKPPAKDPL 898
P + PP AA P G P+ TP SPK PA PL
Sbjct: 1006 KGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP--PSPKGSPAATPL 1052
Score = 70.5 bits (171), Expect = 7e-12
Identities = 135/599 (22%), Positives = 205/599 (34%), Gaps = 74/599 (12%)
Query: 301 PLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGG 360
PL +++P + + +++ + I SP L A S P+ KP+S + S G
Sbjct: 561 PLVQAAPKNSPSFQSTSSSPEIPLSPEATL-AKKSLGEPLPIGKPASSMT------SPLG 613
Query: 361 AAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA 420
++A+ G + G LL + SL + + +DP PT T+ T
Sbjct: 614 VNSSASVIKTDSYAGPDSAGPLL-KSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTT- 671
Query: 421 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF 480
+AS TV+ + P P ASE +P A L
Sbjct: 672 TASPFLEGTVSLAPKNHPVKEGTLTTLP-LVPTASENCPVAPSPQNTCAPLATLV----L 726
Query: 481 APSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAAT 540
AP + +P L P V ++ T++ AP A++P P + A+AT ++
Sbjct: 727 APEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPV--ASSPKECPTEDSGASATASSK 784
Query: 541 AAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQG 600
T + + + P + P + PD SSP
Sbjct: 785 GTLTYLADSPSPLGVSVSPQT-------KRPPTKKGSAGPDTP-------IGNLSSP--- 827
Query: 601 ASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAA 660
SPV S L + LS + SPATT SP G S P +
Sbjct: 828 VSPVEASFLPENSLSFQG-SKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETP 886
Query: 661 SSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDG 720
+ S + P P TPA P A T S+ + P+
Sbjct: 887 TPSVVNLPF----------PKEGPATPA------PKQAPALSMTSSSPKKARATPAPKG- 929
Query: 721 LGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGN-LGISGTTTKKGD 779
+ + +P G P P + PPSP + + A+ + G T + KG
Sbjct: 930 ----IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKG- 984
Query: 780 LQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPP-VAGAPSVGQPGA 838
A P P + G +P +GA P + PP G+P+
Sbjct: 985 -------------APTPPAATPPSPKGGPATPSP-KGAPTPPAVTPPSPKGSPAATPFPK 1030
Query: 839 GFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDP 897
G PPA T P P P P AA +P + P+ TP+ + PPA P
Sbjct: 1031 GASTPPAAT-PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPA-TPSLKGAPTPPAATP 1087
Score = 60.1 bits (144), Expect = 9e-09
Identities = 160/711 (22%), Positives = 243/711 (34%), Gaps = 160/711 (22%)
Query: 298 APSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFS 357
+P+ L+ +SP T TP+ +S P+ L A A +V S++ P + LL P +
Sbjct: 112 SPAALALASPMIAPTL-KGTPS----SSAPLALVALAPHSVQKSSAFPPN-LLTSPPSVA 165
Query: 358 ---SGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEP------ 408
SG +AP P + L+ VPSE + P P
Sbjct: 166 VAESGSVITLSAPIAP--------------SEPKTNLNKVPSEVVPNPKGTPSPPCIVST 211
Query: 409 ---------------------TPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAAS 447
T PTTT IA+ TT+++V G
Sbjct: 212 VPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVK---DTTISSVLISPQNPGSLSLKG 268
Query: 448 PGEAPAA-------------SEGAAAPATPTPVAAAL--------DACSGNDPFAPSEG- 485
P PAA S+ A P TP +L + G+ G
Sbjct: 269 PVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGP 328
Query: 486 SAEAAPELDLFAMKPPETSVP------VVTPTASTAPPVPATA---PSPAPAV---AAAA 533
SA + P + ++ T V+ P S VPAT P AP+V +
Sbjct: 329 SALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTI 388
Query: 534 AATTAATAAATTTTTTSAATATTA-------------PPALDIFGDLFESTPEVAAAPKP 580
++ T + + + T+ + + TT+ P + +TP V P
Sbjct: 389 SSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCT 448
Query: 581 DAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATT---------ASPA 631
AA F SPP + P+ T+ V A AP +T SP
Sbjct: 449 IAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPP 508
Query: 632 KVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNN 691
D + +L SS P + + AS + G+ +P+ + +T ++
Sbjct: 509 LPDPEDLKNL-----PSSVLVKFPTQKDLQTVPASLE------GAPFSPAQAGLTTKKDP 557
Query: 692 LLQPNFEAAFGTTP---STSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMA 748
+ P +AA +P STSSS S L + P G+PA SM P +
Sbjct: 558 TVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPAS-SMTSPLGVNS 616
Query: 749 ASKALGSD-----------LDSSLAS---------LVGNLGISGTTTKKGDLQWNAGEKK 788
++ + +D L SSL + G++ TT K
Sbjct: 617 SASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPF 676
Query: 789 LTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTG 848
L G + PK P G + PL VP S PVA +P P T
Sbjct: 677 LEGTVSLAPKNHPV--KEGTLTTLPL---VPTASENCPVAPSPQ-------NTCAPLAT- 723
Query: 849 MPMMPQQPVMFAQPMMRP---PFGAAAVPGTQLSPSPTPASQSPKKPPAKD 896
+ + P+ P P + P P G V G + + P + SPK+ P +D
Sbjct: 724 LVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTED 774
Score = 55.1 bits (131), Expect = 3e-07
Identities = 111/446 (24%), Positives = 157/446 (35%), Gaps = 96/446 (21%)
Query: 266 DLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPA-KTIDT 324
++ PSS + + L K P A P PA TV SP TPA T
Sbjct: 1515 EVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP-----PAMTVPSPKKTPAIPTPKE 1569
Query: 325 SP--PVDLFATASAAVPVSTSK--PSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWG 380
+P P A++ AV ST K PS L + P +S + AP PPA
Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTS----PSPKEAPTPPA------- 1618
Query: 381 DLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLF 440
+ PS + AP+ TP T+ T S+ + T+ +VT ++
Sbjct: 1619 -----------VTPPSPEKGPATPAPKGTP---TSPPVTPSSLKDSPTSPASVTCKMG-- 1662
Query: 441 GDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKP 500
P AS+G A PT + L A + E+ P + K
Sbjct: 1663 --------ATVPQASKGLPAKKGPTALKEVLVA-----------PAPESTPIITAPTRKG 1703
Query: 501 PETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPA 560
P+T +++T+PP+ P P+ + +T A A S+ TA +
Sbjct: 1704 PQTK-----KSSATSPPI---CPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDAS 1755
Query: 561 LDIFGDLF-----ESTPEVAAA-----PKPDAAPSIDLFSTDAFSSP----PQGASPVPE 606
G L STP AAA PKP++A S A SP P SPVP
Sbjct: 1756 HSPKGPLAPPESKASTPLTAAAFEKVLPKPESA------SVSAAPSPPVSLPLAPSPVPT 1809
Query: 607 SSLTADLL-SVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSA 665
L S SP+ +PA D ++ L P+P S S
Sbjct: 1810 LPPKQQFLPSSPGLVLESPSKPLAPA--DEDELLPLI---------PPEPISGGVPFQSV 1858
Query: 666 SADLLAGFGGSFMAPSPSPVTPAQNN 691
++ P+PS P N
Sbjct: 1859 LVNMPTPKSAGIPVPTPSAKQPVTKN 1884
Score = 54.7 bits (130), Expect = 4e-07
Identities = 123/528 (23%), Positives = 200/528 (37%), Gaps = 62/528 (11%)
Query: 409 TPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASE---GAAAPATPT 465
T P T E+ A + +A++ L P +PA + AA A+P
Sbjct: 8 TVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPF 67
Query: 466 PVAAALDACSGNDPFAPSE-------GSAEAAPELDLFAMKPPETSVPVVTPTASTAPPV 518
P + + + PF S G+A AP + PP + + + AP +
Sbjct: 68 PSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTL 127
Query: 519 PATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGD---LFESTPEVA 575
T S AP A A + ++A T+PP++ + + S P
Sbjct: 128 KGTPSSSAPLALVALAPHSVQKSSA------FPPNLLTSPPSVAVAESGSVITLSAPIAP 181
Query: 576 AAPKP--DAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATT------ 627
+ PK + PS + + SPP S VP +T + S+ + A P TT
Sbjct: 182 SEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVT-PMASIQSGVASLPQTTPTTTLA 240
Query: 628 -ASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADL-LAGFGGSFMAPSPSPV 685
ASP D++ L S S P S A+ S ++ L + P+ P
Sbjct: 241 IASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPD 300
Query: 686 TP-AQNNLLQPNFEAAFGTTP---STSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMV 741
P + + L P +++FG+ T S+ DP+V D + A P+ S++
Sbjct: 301 FPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVD---HSSTGASYPSQRSVI 357
Query: 742 PPSPA--------MAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGA 793
PP P+ +AA + +D +++ S T + G L A L+
Sbjct: 358 PPLPSRNEVVPATVAAFPVVAPSVDKGPSTI-----SSITCSPSGSLN-VATSFSLSPTT 411
Query: 794 NWQPKVAP-ATWSAGVPPSAPLQ--GAVPPTSSVP-PVAGAPSVGQPGAGFGMPPAGTGM 849
+ K +P AT+ + P+ G P + P +A AP+ A PP +G
Sbjct: 412 SLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSG- 470
Query: 850 PMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDP 897
P+ +P A +M P A P TQ++ + + P PP DP
Sbjct: 471 PISNIEPTSPAALVMAPV--APKEPSTQVATT----LRIPVSPPLPDP 512
Score = 39.7 bits (91), Expect = 0.013
Identities = 69/316 (21%), Positives = 105/316 (33%), Gaps = 54/316 (17%)
Query: 259 IDKGDIPDLTQAPSSLM----ETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTV-TS 313
+ + D +P+S+ T+ Q L KK +P +S+P T T
Sbjct: 1642 VTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTR 1701
Query: 314 PNSTPAKTIDTSPPV--DLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAP-- 369
K+ TSPP+ D A + P+ST P+ LL +Q D S A+ +P
Sbjct: 1702 KGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP-LLPVQKDSSKTAKGKDASHSPKG 1760
Query: 370 ---PPPAGGAT-----AWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATAS 421
PP + +T A+ +L + A++S+ PS +S P AP P P +
Sbjct: 1761 PLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPP-VSLPLAPSPVPTLPPKQ----- 1814
Query: 422 ASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFA 481
+SPG + APA + P
Sbjct: 1815 --------------------QFLPSSPGLVLESPSKPLAPADEDELL----------PLI 1844
Query: 482 PSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATA 541
P E + P + P S + PT S PV + +
Sbjct: 1845 PPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQ 1904
Query: 542 AATTTTTTSAATATTA 557
+T TT A A A
Sbjct: 1905 DSTQATTQQAQLAAAA 1920
>gi|33946327 nucleoporin 214kDa [Homo sapiens]
Length = 2090
Score = 97.8 bits (242), Expect = 4e-20
Identities = 163/621 (26%), Positives = 233/621 (37%), Gaps = 83/621 (13%)
Query: 291 GNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLL 350
G S + S S T T P S P T +P F T S +S++ S L
Sbjct: 1428 GGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSATTPS--L 1485
Query: 351 DLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQIS---DPFAPE 407
+ S+ A ++A P P + + + LL E A L P + S +P +
Sbjct: 1486 PMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQ 1545
Query: 408 P------TPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAP--AASEGAA 459
P T ++T+ +A ++ + TT V E +F+ PG+ AA+ +A
Sbjct: 1546 PAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSV-PGQTAVTAAAISSA 1604
Query: 460 APA----TPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVV------T 509
P + TP+A++ + P A + +FA P +S T
Sbjct: 1605 GPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNT 1664
Query: 510 PTASTAPPV-PATAPSPAPAVAAAAAATTAATAAATTTTTTSA----ATATTAPPALDIF 564
TA +A PV A S AP++ +TA+TAAAT ++S A TTAP +F
Sbjct: 1665 ATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAP---GVF 1721
Query: 565 GDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSP 624
G V AA S+ FS FSS P P +S T S F A S
Sbjct: 1722 GQTTFGQASVFGQSASSAA-SVFSFSQPGFSSVPAFGQP---ASSTPTSTSGSVFGAASS 1777
Query: 625 ATTASPAKVDSSGVID---LFGD----AFGSSASEPQPASQAASSSSASADLL-AGFGGS 676
+++S S LFG AFG S Q S +S+A+ +GF
Sbjct: 1778 TSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFC 1837
Query: 677 FMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPS-------VFDGLGDLLMPTM 729
+ S T + FG S+SS S F F GLG
Sbjct: 1838 QASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLG------- 1890
Query: 730 APAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKL 789
G+P+ +P +AS GS S+ ++L GN SG T G + GE+K
Sbjct: 1891 ---GKPSQ-DAANKNPFSSASGGFGSTATSNTSNLFGN---SGAKTFGGFASSSFGEQKP 1943
Query: 790 TGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGM 849
TG T+S+G S QG + + GA V FG PP G
Sbjct: 1944 TG-----------TFSSG-GGSVASQGFGFSSPNKTGGFGAAPV------FGSPPTFGGS 1985
Query: 850 PMMPQQPVMFAQPMMRPPFGA 870
P P + P P G+
Sbjct: 1986 PGFGGVPAFGSAPAFTSPLGS 2006
Score = 76.3 bits (186), Expect = 1e-13
Identities = 124/508 (24%), Positives = 190/508 (37%), Gaps = 80/508 (15%)
Query: 271 PSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNST------------P 318
PSSL + L + G + G + S P+ + SS + T T P T P
Sbjct: 1323 PSSLAG---ETLGSFSGLRVGQADDSTKPTNKA-SSTSLTSTQPTKTSGVPSGFNFTAPP 1378
Query: 319 AKTIDTSPPVDLFATA-SAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGAT 377
T PPV AT S A P +TS S+ + P S+G + + AG +
Sbjct: 1379 VLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTS 1438
Query: 378 AWGDLLGEDSLAALSSVPSEAQISDPFAPEPTP-----PTTTAEIATASASASTTTT--- 429
S S+VP P AP PT PT+ ++ S +S TT
Sbjct: 1439 -----FSFGSQQTNSTVP-------PSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLP 1486
Query: 430 VTAVTAEVDLFGDAFAASPGEAPAASEGAA------APATPTPVAAALDACSGNDPFAPS 483
++A + + A PG++ ++ A+ + P D+ A
Sbjct: 1487 MSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQP 1546
Query: 484 --EGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATA 541
S AA L A+ T P A T PA++ S A AAA ++A
Sbjct: 1547 AVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGP 1606
Query: 542 AATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFS-TDAFSSPPQG 600
A T++T A++TT+ VA P +AA + S + F+ PP
Sbjct: 1607 VAVETSSTPIASSTTS---------------IVAPGPSAEAAAFGTVTSGSSVFAQPPAA 1651
Query: 601 ASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAA 660
+S + LT + A +P+ T +V +S LFG GS+AS Q +
Sbjct: 1652 SSSSAFNQLTNN-------TATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVS 1704
Query: 661 SSSSASADL---------LAGFGGSFMAPSPSPVTPAQNNLLQPNFEA--AFGTTPSTSS 709
SS +S FG + + + + + QP F + AFG P++S+
Sbjct: 1705 SSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFG-QPASST 1763
Query: 710 SSSFDPSVFDGLGDLLMPTMAPAGQPAP 737
+S SVF + GQ +P
Sbjct: 1764 PTSTSGSVFGAASSTSSSSSFSFGQSSP 1791
Score = 58.5 bits (140), Expect = 3e-08
Identities = 97/449 (21%), Positives = 155/449 (34%), Gaps = 81/449 (18%)
Query: 445 AASPGEAPAASEGAAAPATPTPVAAALDACSG-------------------NDPFAPSEG 485
A SP +A + AAA A +A+ A + N+P PS
Sbjct: 1079 APSPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVPQVVNVQELKNNPATPSTA 1138
Query: 486 SAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPS-PAPAVAAAAAATTAATAAAT 544
+ P A P PV A + + PS P PA ++ A+ A
Sbjct: 1139 MGSSVPYST--AKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASGTAKI 1196
Query: 545 TTTTTSAATATT--------APPALDIFGDLFESTPEVAAAPKPDAAPSI------DLFS 590
T TS +A+ +P + TP A PS D FS
Sbjct: 1197 ETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFS 1256
Query: 591 TDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSA 650
+ S P A +PESS + + S PA ++S S G A +++
Sbjct: 1257 SGGGSKPSYEA--IPESSPPSGITSASNTTPGEPAASSSRPVAPS-------GTALSTTS 1307
Query: 651 SE----PQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPS 706
S+ P + SS + + L F G + + P + + + T P+
Sbjct: 1308 SKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTN----KASSTSLTSTQPT 1363
Query: 707 TSSS--SSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASL 764
+S S F+ + LG P + + S+ PP+ +S A+ L + A
Sbjct: 1364 KTSGVPSGFNFTAPPVLGKHTEPPVTSSA--TTTSVAPPAATSTSSTAVFGSLPVTSAGS 1421
Query: 765 VGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSV 824
G + GT+ G ++ G ++ ++ VPPSAP PPT++
Sbjct: 1422 SGVISFGGTSLSAGKTSFSFGSQQT---------------NSTVPPSAP-----PPTTAA 1461
Query: 825 PPVAGAPSVGQPGAGFGMPPAGTGMPMMP 853
P+ P FG + P +P
Sbjct: 1462 TPL----PTSFPTLSFGSLLSSATTPSLP 1486
Score = 57.8 bits (138), Expect = 5e-08
Identities = 88/298 (29%), Positives = 112/298 (37%), Gaps = 42/298 (14%)
Query: 464 PTPVAAALDACSGNDPFA-----PSEGSAEAAPE-LDLFAMKPPETSVPVVTPTASTAPP 517
P PV L PF P S PE L L + P++ P TPT P
Sbjct: 385 PAPVLMLLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKS--PGSTPTT----P 438
Query: 518 VPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAA 577
+ AP A AAAA A+ ++ A T S A AP +S+ V
Sbjct: 439 TSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGE 498
Query: 578 PKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSG 637
P PS +S+ + SS A+P P S + + A AP+PA ASP ++
Sbjct: 499 P-----PS---YSSGSDSSK---AAPGPGPSTFSFVPPSKASLAPTPA--ASPVAPSAAS 545
Query: 638 VIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNF 697
+FGSS +P S S SA M PS P T A L F
Sbjct: 546 F------SFGSSGFKPTLESTPVPSVSAP--------NIAMKPSFPPSTSAVKVNLSEKF 591
Query: 698 EAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGS 755
AA +TP +SS S+ S F P P P+S PPS S L S
Sbjct: 592 TAAATSTPVSSSQSAPPMSPFSSASK--PAASGPLSHPTPLS-APPSSVPLKSSVLPS 646
Score = 57.8 bits (138), Expect = 5e-08
Identities = 78/299 (26%), Positives = 123/299 (41%), Gaps = 55/299 (18%)
Query: 273 SLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSP--PVDL 330
SL++T E+ +LEG++ + GS +P S +P S + PA +SP P+
Sbjct: 412 SLIKTPERL--SLEGERQPKSPGSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIAT 469
Query: 331 FATASAA-VPV------STSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLL 383
F+ A P S+ K S+ + P +SSG ++ AAP P P
Sbjct: 470 FSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGP------------ 517
Query: 384 GEDSLAALSSVP-SEAQISDPFAPEPTPPTTTAEIATASASAST--TTTVTAVTAEVDLF 440
+ S VP S+A ++ A P P+ + +S T +T V +V+A
Sbjct: 518 -----STFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNIAM 572
Query: 441 GDAFAASPGEAPA-ASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAM- 498
+F S SE A AT TPV+ S+++AP + F+
Sbjct: 573 KPSFPPSTSAVKVNLSEKFTAAATSTPVS-----------------SSQSAPPMSPFSSA 615
Query: 499 KPPETSVPVVTPTASTAPP--VP---ATAPSPAPAVAAAAAATTAATAAATTTTTTSAA 552
P S P+ PT +APP VP + PSP+ A +++ + + T AA
Sbjct: 616 SKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPSGRSAQGSSSPVPSMVQKSPRITPPAA 674
Score = 54.7 bits (130), Expect = 4e-07
Identities = 114/517 (22%), Positives = 180/517 (34%), Gaps = 105/517 (20%)
Query: 385 EDSLAALSSVPS------EAQISDPFAPEPTPPTTTAEIATASASA-------------S 425
E +L VP+ +AQ+ + A TPP + A+ S SA S
Sbjct: 926 ESHTKSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVS 985
Query: 426 TTTTVTAVTAEVDLF-----GDAFAASPGEAPAASEGAAAPATPTPVA--AALDACSGND 478
+T++V+ D +A +P AP + P+ A A G+
Sbjct: 986 STSSVSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSS 1045
Query: 479 PFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTA 538
P A +A ++ + S + T T P P+ P AP AAAAA
Sbjct: 1046 PGVMGTSVATSASKI----IPQGADSTMLATKTVKHGAPSPSH-PISAPQAAAAAALRRQ 1100
Query: 539 ATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSP- 597
+ A T + +T P +++ ++ P + + P +ST P
Sbjct: 1101 MASQAPAVNTLTESTLKNVPQVVNV--QELKNNPATPSTAMGSSVP----YSTAKTPHPV 1154
Query: 598 --PQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQP 655
P A+ + SL L + P+PA+ + +SG + + ++ Q
Sbjct: 1155 LTPVAANQAKQGSLINSLKP----SGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQF 1210
Query: 656 ASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDP 715
+ + S S + GF + P+PS NF AA G TPST SS P
Sbjct: 1211 SKPFSFSPSGT-----GFNFGIITPTPSS-----------NFTAAQGATPSTKESS--QP 1252
Query: 716 SVFDGLGDL-----LMPTMAP-----------AGQPAPVSMVPPSPAMAASKALGSDLD- 758
F G +P +P G+PA S P +P+ A S L+
Sbjct: 1253 DAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGTALSTTSSKLET 1312
Query: 759 --SSLASLVGNLGISGTT---------------TKKGDLQWNAGEKKLTGGANWQPKVAP 801
S L L+ ++G T TK + A LT + P
Sbjct: 1313 PPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTN---KASSTSLTSTQPTKTSGVP 1369
Query: 802 ATWSAGVPP------SAPLQGAVPPTSSVPPVAGAPS 832
+ ++ PP P+ + TS PP A + S
Sbjct: 1370 SGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTS 1406
Score = 46.2 bits (108), Expect = 1e-04
Identities = 77/337 (22%), Positives = 118/337 (35%), Gaps = 64/337 (18%)
Query: 320 KTIDTSPPVDLFATASAAVP---VSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGA 376
KT+ +P + L +T P ++ + L+ S G +P P +
Sbjct: 381 KTLPPAPVLMLLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTS 440
Query: 377 TAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA-----SASASTTTTVT 431
+ L + AA +S+P S P AP T A A S+S ++ TVT
Sbjct: 441 SQAPQKLDASAAAAPASLPP----SSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVT 496
Query: 432 AVTAEVDLFGDAFAASPGEAPA------------ASEGAAAPATPTPVAAALDACSGNDP 479
D+ A+PG P+ A AA+P P+ + + G+
Sbjct: 497 GEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSF----GSSG 552
Query: 480 FAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAA-ATTA 538
F P+ S TP S + P A PS P+ +A +
Sbjct: 553 FKPTLES----------------------TPVPSVSAPNIAMKPSFPPSTSAVKVNLSEK 590
Query: 539 ATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAA-----PKPDAAPSIDLFSTDA 593
TAAAT+T +S+ +A P F S + AA+ P P +AP + +
Sbjct: 591 FTAAATSTPVSSSQSAPPMSP--------FSSASKPAASGPLSHPTPLSAPPSSVPLKSS 642
Query: 594 FSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASP 630
P G S SS ++ P A SP
Sbjct: 643 VLPSPSGRSAQGSSSPVPSMVQKSPRITPPAAKPGSP 679
Score = 45.8 bits (107), Expect = 2e-04
Identities = 83/331 (25%), Positives = 121/331 (36%), Gaps = 52/331 (15%)
Query: 583 APSIDLFSTDAFSSPPQ--GASPVPESSL-TADLLSVDAFAAP-SPATT-ASPAKVDSSG 637
AP + L STD P +P +S + T + LS++ P SP +T +P +
Sbjct: 386 APVLMLLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQ 445
Query: 638 VIDLFGDAFGSSASEPQPASQAASSS---SASADLLAGFGGSFMAPSPSPVTPAQNNLLQ 694
+D A +S PA+ A+ S + A + FG S + S +
Sbjct: 446 KLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVT--------- 496
Query: 695 PNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALG 754
G PS SS S + AP P+ S VPPS A A
Sbjct: 497 -------GEPPSYSSGSDSSKA-------------APGPGPSTFSFVPPSKASLAPTPAA 536
Query: 755 SDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPL 814
S + S AS + G SG K L+ +P P+T + V S
Sbjct: 537 SPVAPSAASF--SFGSSGF---KPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSEKF 591
Query: 815 QGA-----VPPTSSVPPVAGAPSVGQPGAGFGM---PPAGTGMPMMPQQPVMFAQPMMRP 866
A V + S PP++ S +P A + P +P + + P R
Sbjct: 592 TAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPSGRS 651
Query: 867 PFGAAA-VPG-TQLSPSPTPASQSPKKPPAK 895
G+++ VP Q SP TP + P P AK
Sbjct: 652 AQGSSSPVPSMVQKSPRITPPAAKPGSPQAK 682
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 97.8 bits (242), Expect = 4e-20
Identities = 132/595 (22%), Positives = 231/595 (38%), Gaps = 70/595 (11%)
Query: 295 GSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASA---AVPVST----SKPSS 347
G+ + +P+ S+P TT T +S+P P+ + S ++PVST S +S
Sbjct: 2828 GTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEAS 2887
Query: 348 DLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQI--SDPFA 405
L D S + + P A G + E S S + S + S+
Sbjct: 2888 TLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEAST 2947
Query: 406 PEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGD--------AFAASPGEAPAASEG 457
TP T + T++ ++S+ TT + + G+ + + P + AS
Sbjct: 2948 LSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTL 3007
Query: 458 AAAPA-TPTPVAAALDACS--------GNDPFAPSEGSAE-----------AAPELDLFA 497
+ PA T TPV + +A S G PSEGS A PE +
Sbjct: 3008 SRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLS 3067
Query: 498 MKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTA 557
P +++ PVVT T ++ P PA S P + +T +TT TS+A +T +
Sbjct: 3068 TTPVDSNSPVVTSTEVSSSPTPAEGTS-MPISTYSEGSTPLTGVPVSTTPVTSSAISTLS 3126
Query: 558 PPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLL--S 615
+D STP V + + ++P+ ++ S+P +G++P+ ++ L+ S
Sbjct: 3127 TTPVD------TSTP-VTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSS 3179
Query: 616 VDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGG 675
D+ + +P T++P + + S P +S S +A
Sbjct: 3180 EDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEA 3239
Query: 676 SFMAPSP----SPVT---------PAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLG 722
S ++ +P +P+T P P + G+TP TS S +V
Sbjct: 3240 SILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVS-TTTVASSET 3298
Query: 723 DLLMPTMAPAGQPAPV-SMVPPSPAMAASKALGSDLDSSLASLVGNLGISGT---TTKKG 778
L T A P S SP +A ++ + S ++ + N+ S T +++
Sbjct: 3299 STLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEAS 3358
Query: 779 DLQWNAGEKKLTGGANWQPKVAPAT-WSAGVPPSAPLQGAVP----PTSSVPPVA 828
L + + + ++P T +P S+P +G P P S+ P V+
Sbjct: 3359 TLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVS 3413
Score = 92.8 bits (229), Expect = 1e-18
Identities = 143/637 (22%), Positives = 240/637 (37%), Gaps = 116/637 (18%)
Query: 267 LTQAPSSLMETLEQHLNTL-------EGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPA 319
LT P S +TL +G +NE S +P+P +S T+ S TP
Sbjct: 1280 LTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPL 1339
Query: 320 KTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAW 379
TS PV+ AS+A+ + ++ P D S+ + A + P + G +
Sbjct: 1340 ----TSIPVNTTLVASSAISILSTTPV--------DNSTPVTTSTEACSSPTTSEGTSM- 1386
Query: 380 GDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDL 439
+S PSE P T P ++E +T SA+ T+T +AE
Sbjct: 1387 -----------PNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEAT- 1434
Query: 440 FGDAFAASPGEAPAASEGAAAP-ATPTPVAAALDACS-GNDPFAPSEGSAEAAPELDLFA 497
+P +EG + P +TP+ L + N P A SE S +
Sbjct: 1435 ----------SSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEAST--------LS 1476
Query: 498 MKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTA 557
P +++ PVVT TA ++ P PA S A + + + + +TTT +S + +
Sbjct: 1477 TTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLST 1536
Query: 558 PPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVD 617
PA+ STP V + ++P+ ++ S+ +G++P+ ++ L+
Sbjct: 1537 TPAV-------TSTP-VTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLV--- 1585
Query: 618 AFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSF 677
S A T S +DS + +A SS++ + +S S+ S + LL
Sbjct: 1586 ---VSSEANTLSTTPIDSKTQVTASTEA--SSSTTAEGSSMTISTPSEGSPLLTS----- 1635
Query: 678 MAPSPSPV-TPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPA 736
+ S +PV +P + L ++ ST SSS P+ +G MPT
Sbjct: 1636 IPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSS--PTPAEGTS---MPTSTYTEGRT 1690
Query: 737 PVSMVPPSPAMAASKALG----SDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGG 792
P++ + AS A+ + +D+S S TT +G
Sbjct: 1691 PLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEG-------------- 1736
Query: 793 ANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMM 852
+P S P +G P TS PV+ P + + P T P+
Sbjct: 1737 -------------TSMPNSTPSEGTTPLTSI--PVSTTPVLSSEASTLSATPIDTSTPVT 1781
Query: 853 PQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSP 889
+ ++P + LS TP + +P
Sbjct: 1782 TSTEATSSPTTAE----GTSIPTSTLSEGMTPLTSTP 1814
Score = 90.1 bits (222), Expect = 8e-18
Identities = 134/614 (21%), Positives = 229/614 (37%), Gaps = 110/614 (17%)
Query: 300 SPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASA---AVPVST----SKPSSDLLDL 352
+P+ ++P TT T S+ TS P + S ++PV+T S +S L
Sbjct: 652 TPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTT 711
Query: 353 QPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPT 412
D S+ + A + P A GA+ +S PSE S P P T
Sbjct: 712 PVDTSTPVTTSTEASSSPTTADGASM------------PTSTPSEG--STPLTSMPVSKT 757
Query: 413 --TTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAP-ATPTPVAA 469
T++E +T S + T+T + E +P +EG + P +TP+ +
Sbjct: 758 LLTSSEASTLSTTPLDTSTHITTSTEASC-----------SPTTTEGTSMPISTPSEGSP 806
Query: 470 ALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAV 529
L + P + +PE + P +++ PV T T ++ P PA S +
Sbjct: 807 LLTSI-------PVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTST 859
Query: 530 AAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLF 589
+ + +TT TSA + + P +++ V + + ++P+
Sbjct: 860 YSEGRTPLTSMPVSTTLVATSAISTLSTTPV--------DTSTPVTNSTEARSSPTTSEG 911
Query: 590 STDAFSSPPQGASP---VPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAF 646
++ S+P +G++P +P+S T ++S S A T S VD+S + +A
Sbjct: 912 TSMPTSTPGEGSTPLTSMPDS--TTPVVS-------SEARTLSATPVDTSTPVTTSTEA- 961
Query: 647 GSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTP- 705
S P A + +S ++ +P TP + L+ + + TTP
Sbjct: 962 ---TSSPTTAEGTSIPTSTPSE----------GTTPLTSTPVSHTLVANSEASTLSTTPV 1008
Query: 706 ------STSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALG----S 755
+TS+ +S P +G MPT P+ P++ +P S M AS +
Sbjct: 1009 DSNTPLTTSTEASSPPPTAEGTS---MPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTT 1065
Query: 756 DLDSSLASLVGNLGISGTTTKKGDLQ----WNAGEKKLTGGANWQPKVAPATWSAGVPPS 811
D+S + S +TT G ++ G LT P + V
Sbjct: 1066 PADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTS--------VPVSTRLVVSSE 1117
Query: 812 APLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAA 871
A P +S+P + P GT +P P P P+ P
Sbjct: 1118 ASTLSTTPVDTSIPVTTSTEASSSPTTA-----EGTSIPTSP--PSEGTTPLASMPVSTT 1170
Query: 872 AVPGTQLSP-SPTP 884
V ++ + S TP
Sbjct: 1171 LVVSSEANTLSTTP 1184
Score = 89.0 bits (219), Expect = 2e-17
Identities = 131/645 (20%), Positives = 246/645 (38%), Gaps = 81/645 (12%)
Query: 291 GNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVD--------LFATASAAVPVST 342
G+ + + +P+ +P TT +S+P TS P+ L + + + +PV++
Sbjct: 2942 GSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVAS 3001
Query: 343 SKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALS--------SV 394
S+ +S L D S+ + A + P A G E S S ++
Sbjct: 3002 SE-ASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAI 3060
Query: 395 PSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAE--VDLFGDAFAASPGEAP 452
P + +S +P T+ E++++ A T+ + +E L G + +P +
Sbjct: 3061 PEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSS 3120
Query: 453 AASEGAAAPA-TPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVP----- 506
A S + P T TPV + +A S +P+ + P P T +P
Sbjct: 3121 AISTLSTTPVDTSTPVTTSTEAHS-----SPTTSEGTSMPTSTPSEGSTPLTYMPVSTML 3175
Query: 507 VVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGD 566
VV+ ST P +P A ++TTA + T+T + T T+ P +
Sbjct: 3176 VVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNT--P 3233
Query: 567 LFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQG-------ASPVPESSLTADLLSVDAF 619
+ S + + D+ + ST+A SSPP ++P S+ +
Sbjct: 3234 VASSEASILSTTPVDSNTPLTT-STEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTT 3292
Query: 620 AAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMA 679
A S +T S D+S + + A S + ++ S S L + M+
Sbjct: 3293 VASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPL------TNMS 3346
Query: 680 PSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVS 739
S +PV ++ + L T +TS+ +S P+ +G +PT +P+ P++
Sbjct: 3347 FSTTPVVSSEASTLSTT-PVDTSTPVTTSTEASLSPTTAEGTS---IPTSSPSEGTTPLA 3402
Query: 740 MVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKV 799
+P ++ + + S++++ + V + + T+T+ A+ P +
Sbjct: 3403 SMP----VSTTPVVSSEVNTLSTTPVDSNTLVTTSTE----------------ASSSPTI 3442
Query: 800 APATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMF 859
A T +P S +G+ P S+ P++ P + P T P+ P
Sbjct: 3443 AEGT---SLPTSTTSEGSTP--LSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNS 3497
Query: 860 A------QPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDPL 898
+ M G + P T + S TP + S + P+
Sbjct: 3498 SPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPV 3542
Score = 88.6 bits (218), Expect = 2e-17
Identities = 142/658 (21%), Positives = 247/658 (37%), Gaps = 49/658 (7%)
Query: 261 KGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAK 320
+G P LT P S M + +TL + + + S+ A + P STP++
Sbjct: 3161 EGSTP-LTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSE 3219
Query: 321 --TIDTSPPVDLFATASAAVPVSTSKP--SSDLLDLQPDFSSGGAAAAAAPAP-PPPAGG 375
T TS PV AS+ + ++ P S+ L + SS A P P+ G
Sbjct: 3220 GMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEG 3279
Query: 376 ATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTA 435
+T + + A S + +S A TP TT ++ +++ A T+ T+ +
Sbjct: 3280 STPLTSMPVSTTTVASSET---STLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYS 3336
Query: 436 E--VDLFGDAFAASPGEAPAASEGAAAPA-TPTPVA----AALDACSGNDPFAPSEGSAE 488
E L +F+ +P + AS + P T TPV A+L + P+ +E
Sbjct: 3337 EGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSE 3396
Query: 489 AAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTT 548
L P ++ PVV+ +T P + + A+++ T A + T+T
Sbjct: 3397 GTTPL----ASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTST 3452
Query: 549 TSAATA------TTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGAS 602
TS + + P +TP + P ++P+ +T +S P +
Sbjct: 3453 TSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTA 3512
Query: 603 PVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASS 662
+ LT +S A+ S A+T S VDS+ + A S A+ + ++
Sbjct: 3513 GEGSTPLTNMPVSTTPVAS-SEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTP 3571
Query: 663 SSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLG 722
S S+ L S S TP+ P+ + + T ST S+S+ P
Sbjct: 3572 SEGSSSLTTMLLSSTYVTSSEASTPS-----TPSVDRSTPVTTSTQSNSTPTPPEV---- 3622
Query: 723 DLLMPTMAPAGQPAPVSMVPPSPAMAASKALGS----DLDSSLASLVGNLGISGTTTKKG 778
+ +P P+ P++++P S G+ +D+S + S T +G
Sbjct: 3623 -ITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEG 3681
Query: 779 DLQ--WNAGEKKLTGGANWQPKVAPATWSAGVPPSAP-LQGAVPPTSSVPPVAGAPSVGQ 835
W E T T S G S P + + P T+S ++ + ++
Sbjct: 3682 TTMPIWTPSEGS-TPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDS 3740
Query: 836 PGAGFGMPPAGTGMPMMPQQPVMFAQPMMR-PPFGAAAVPGTQLSPSPTPASQSPKKP 892
MP + + ++ P+ R P ++P S S T AS+ P
Sbjct: 3741 TTMSVSMP---MEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSP 3795
Score = 86.3 bits (212), Expect = 1e-16
Identities = 138/673 (20%), Positives = 251/673 (37%), Gaps = 118/673 (17%)
Query: 262 GDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKT 321
G LT+ P S+M + +TL + +P + + P T T +S+P
Sbjct: 272 GGSTPLTRMPLSVMLVVSSEASTL------------STTPAATNIPVITSTEASSSPTTA 319
Query: 322 IDTSPPVDLF--------ATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPA 373
TS P + +T ++ +PV+TS+ S+ L + P +S + P+ P
Sbjct: 320 EGTSIPTSTYTEGSTPLTSTPASTMPVATSEMST--LSITPVDTSTLVTTSTEPSSLPTT 377
Query: 374 GGATAWGDLLGEDSLAALSSVP--------SEAQISDPFAPEPTPPTTTAEIATASASAS 425
AT+ + L+++P SEA + + TTA A++S + +
Sbjct: 378 AEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTA 437
Query: 426 TTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF----- 480
T++ T S G P S P + TPVA++ + P
Sbjct: 438 EDTSIATSTP-----------SEGSTPLTS----MPVSTTPVASSEASNLSTTPVDSKTQ 482
Query: 481 -APSEGSAEAAPELDLFAMK---PPETSVPVVTPTASTAP------------PVPATAPS 524
S ++ + P ++ +M P E S P+ + + ST P PV + P
Sbjct: 483 VTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPV 542
Query: 525 PAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAP 584
+ A++++ T T+ T+T + + T P + + ST A D+
Sbjct: 543 TTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPA---DSNT 599
Query: 585 SIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGD 644
+ S + SS + +P S+ + ++ + + + +S A S+ +D
Sbjct: 600 FVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVD---- 655
Query: 645 AFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPS-PSPVTPAQNNLLQPNFEAAFGT 703
++ P S A+SSS +A+ + ++ S P P L+ + + T
Sbjct: 656 -----SNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLST 710
Query: 704 TP-------STSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSD 756
TP +TS+ +S P+ DG MPT P+ P++ +P S +
Sbjct: 711 TPVDTSTPVTTSTEASSSPTTADGAS---MPTSTPSEGSTPLTSMPVSKTL--------- 758
Query: 757 LDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQG 816
L SS AS + + +T + A+ P T +P S P +G
Sbjct: 759 LTSSEASTLSTTPLDTSTHITTSTE-----------ASCSPTTTEGT---SMPISTPSEG 804
Query: 817 AVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGT 876
+ P + PV+ P + P + P+ V + P ++P +
Sbjct: 805 S--PLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSP----TPAEGTSMPTS 858
Query: 877 QLSPSPTPASQSP 889
S TP + P
Sbjct: 859 TYSEGRTPLTSMP 871
Score = 83.2 bits (204), Expect = 1e-15
Identities = 141/634 (22%), Positives = 244/634 (38%), Gaps = 83/634 (13%)
Query: 300 SPLSKSSPATTVTSPNSTPAKTIDTSPPVDL---FATASAAVPVST----SKPSSDLLDL 352
+P+ S P TT T +S+P DTS P+ +T+ ++ VST S +S L
Sbjct: 2597 TPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTT 2656
Query: 353 QPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAP--EPTP 410
D + + + P A G++ GE S + + S +++ A TP
Sbjct: 2657 PVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTP 2716
Query: 411 PTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPG----EAPAASEGAAAPATPT- 465
T+ + T++ ++S+ TT + + D P AS A+ +T
Sbjct: 2717 VDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAV 2776
Query: 466 ----PVAAALDACSGNDPF--------APSEGSAE-----------AAPELDLFAMKPPE 502
PV + +A S PSE S A+ E + P +
Sbjct: 2777 DTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVD 2836
Query: 503 TSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTT---TTSAATATTAPP 559
TS PV T T +++ P TA ++ A+ +T T+ +TT ++ A+T +T P
Sbjct: 2837 TSTPVTTSTKASSS--PTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTP- 2893
Query: 560 ALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAF 619
+++ V + + ++P+ ++ S+P + ++P LT+ L+S
Sbjct: 2894 --------VDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTP-----LTSILVSTVPV 2940
Query: 620 AAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMA 679
A S A+T S VD+ + +A SS + + S S+ L M+
Sbjct: 2941 AG-SEASTLSTTPVDTRTPVTTSAEA-SSSPTTAEGTSMPISTPGERRTPLTS-----MS 2993
Query: 680 PSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVS 739
S PV ++ + L A T +TS+ +S P+ +G G +P P+ P++
Sbjct: 2994 VSTMPVASSEASTLS-RTPADTSTPVTTSTEASSSPTTAEGTG---IPISTPSEGSTPLT 3049
Query: 740 MVPPSP---AMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQ 796
+P S A+ + L + S + +V + +S + T E + +
Sbjct: 3050 SIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPT--------PAEGTSMPISTYS 3101
Query: 797 PKVAPATWSAGVPPS-APLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQ 855
P T GVP S P+ + T S PV + V P G M
Sbjct: 3102 EGSTPLT---GVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTST 3158
Query: 856 PVMFAQPMMRPPFGAAAVPGTQLSP-SPTPASQS 888
P + P+ P V ++ S S TP S
Sbjct: 3159 PSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTS 3192
Score = 82.8 bits (203), Expect = 1e-15
Identities = 141/655 (21%), Positives = 252/655 (38%), Gaps = 92/655 (14%)
Query: 268 TQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATT--VTSPNSTPAKT-IDT 324
T P + T EG + S +PL+ +TT V+S T + T +DT
Sbjct: 2424 TSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDT 2483
Query: 325 SPPVDLFATASAA--------VPVSTSKPSSDLLDLQPDFSSGGAA--AAAAPAPPPPAG 374
S P+ AS++ VP+ST+ S LL P ++ A+ A+ P +
Sbjct: 2484 STPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSN 2543
Query: 375 GATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTV-TAV 433
+ + +A + + S+ P + P +T +A++ AS +TT V T++
Sbjct: 2544 SPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSI 2603
Query: 434 TAEVDLFGDAFAASPGEAPAASEGAAAP-ATPTPVAAALDA-CSGNDPFAPSEGSAEAAP 491
+ +P ++ + P +TP+ V+ +L + P A SE S
Sbjct: 2604 PVTT-------STETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEAST---- 2652
Query: 492 ELDLFAMKPPETSVPVVTPTASTAPPVPATAPS-PAPAVAAAAAATTAATAAATTTTTTS 550
+ P +T V T T +++ P A S P + T + T +
Sbjct: 2653 ----LSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSE 2708
Query: 551 AATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLT 610
A+T +T P + STP V + + ++P+ ++ S+P G++P+ +S+
Sbjct: 2709 ASTLSTTP--------VDTSTP-VTTSAEASSSPTTAEGTSMRISTPSDGSTPL--TSIL 2757
Query: 611 ADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLL 670
L V A S A+T S VD+S + +A S + + ++ S S L
Sbjct: 2758 VSTLPV----ASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLT 2813
Query: 671 AGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMA 730
+ M + +PV ++ L T +TS+ +S P+ +G +++P
Sbjct: 2814 S------MPVNHTPVASSEAGTLSTT-PVDTSTPVTTSTKASSSPTTAEG---IVVPIST 2863
Query: 731 PAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLT 790
+ ++ +P S AS S+L++ + I TT+ +G
Sbjct: 2864 ASEGSTLLTSIPVSTTPVASSEA-----STLSTTPVDTSIPVTTSTEG------------ 2906
Query: 791 GGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMP 850
+ P A T +P S P + + P TS + V+ P G + P T P
Sbjct: 2907 ---SSSPTTAEGT---SMPISTPSEVSTPLTSIL--VSTVPVAGSEASTLSTTPVDTRTP 2958
Query: 851 M--------MPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDP 897
+ P + P+ P G P T +S S P + S ++ P
Sbjct: 2959 VTTSAEASSSPTTAEGTSMPISTP--GERRTPLTSMSVSTMPVASSEASTLSRTP 3011
Score = 82.4 bits (202), Expect = 2e-15
Identities = 159/721 (22%), Positives = 258/721 (35%), Gaps = 127/721 (17%)
Query: 265 PDLTQAPSSLMETLEQHLNTLEGKKPGNN-------EGSGAPSPLSKSSPATTVTSPNST 317
P LT P S+ +TL +N E S +P+P +S T+ S T
Sbjct: 806 PLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRT 865
Query: 318 PAKTIDTSPPVDLFATASAAV------PVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPP 371
P TS PV A++A+ PV TS P ++ + + SS + +
Sbjct: 866 PL----TSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEAR---SSPTTSEGTSMPTST 918
Query: 372 PAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVT 431
P G+T + DS + V SEA+ + + P TT+ AT+S + + T++
Sbjct: 919 PGEGSTPLTSM--PDSTTPV--VSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIP 974
Query: 432 AVTAEVDLFGDAFAASPGEAPAASEGAAAPATP----TPVAAALDACS--------GNDP 479
T A SE + TP TP+ + +A S
Sbjct: 975 TSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPT 1034
Query: 480 FAPSEGSAE-----------AAPELDLFAMKPPETSVPVVT----------------PTA 512
PSEGS A+ E + P +TS PV T PT+
Sbjct: 1035 STPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTS 1094
Query: 513 S--------TAPPVP------------ATAP--SPAPAVAAAAAATTAATAAATTTTTTS 550
+ T+ PV +T P + P + A+++ TA T+ T+
Sbjct: 1095 TYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSP 1154
Query: 551 AATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQG-------ASP 603
+ TT ++ + L S+ + P + + ST+A S PP ++P
Sbjct: 1155 PSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTP 1214
Query: 604 VPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSS 663
S+ + A S A+T S + VD+S + + SS + + S S++
Sbjct: 1215 GERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAET-SSSPTTAEGTSLPTSTT 1273
Query: 664 SASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGD 723
S + LL S + +P + LL + S SSS P+ +G
Sbjct: 1274 SEGSTLLT----SIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSS--PTPAEGTS- 1326
Query: 724 LLMPTMAPAGQPAPVSMVPPSPAMAASKALG----SDLDSSLASLVGNLGISGTTTKKGD 779
MPT + P++ +P + + AS A+ + +D+S S TT +G
Sbjct: 1327 --MPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGT 1384
Query: 780 LQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAG 839
N+ + T P + + V A A P +S P A + P
Sbjct: 1385 SMPNSNPSEGTTPLT----SIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTA 1440
Query: 840 FGMPPAGTGMPMMPQQPVMFAQPMMRPPF---------------GAAAVPGTQLSPSPTP 884
G+ T P + P+ + P+ P + V T +S SPTP
Sbjct: 1441 EGI-SIPTSTPSEGKTPLK-SIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTP 1498
Query: 885 A 885
A
Sbjct: 1499 A 1499
Score = 82.0 bits (201), Expect = 2e-15
Identities = 130/592 (21%), Positives = 222/592 (37%), Gaps = 73/592 (12%)
Query: 284 TLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTI---DTSPPVDLFATASAAVPV 340
T EG + S +PL+ +TT + + T + DTS PV ++ AS++ P+
Sbjct: 3265 TAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPI 3324
Query: 341 S--TSKPSSDLLD-----------LQPDFSSGGAAAAAAP---APPPPAGGATAWGDLLG 384
+ TS P+S + P SS + + P + P +
Sbjct: 3325 ADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTA 3384
Query: 385 EDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAF 444
E + SS PSE P T P ++E+ T S + + T+ + E
Sbjct: 3385 EGTSIPTSS-PSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEAS------ 3437
Query: 445 AASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFA--PSEGSAEAAPELDLFAMKPPE 502
+P +EG + P + T G+ P + P + A+ E + P +
Sbjct: 3438 -----SSPTIAEGTSLPTSTTS--------EGSTPLSIMPLSTTPVASSEASTLSTTPVD 3484
Query: 503 TSVPVVTPTASTAPPVPATAPS-PAPAVAAAAAATTAATAAATTTTTTSAATATTAPPAL 561
TS PV T + + + P A S P + T + T ++ A+T +T P
Sbjct: 3485 TSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTP--- 3541
Query: 562 DIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAA 621
+S V ++ + ++P+ +T S+P +G+ SSLT LLS +
Sbjct: 3542 ------VDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGS-----SSLTTMLLS-STYVT 3589
Query: 622 PSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPS 681
S A+T S VD S + + S+ + P+ + S+ S + L + M S
Sbjct: 3590 SSEASTPSTPSVDRSTPVTTSTQS-NSTPTPPEVITLPMSTPSEVSTPL-----TIMPVS 3643
Query: 682 PSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMV 741
+ VT ++ T TS+ S P +G MP P+ P++ +
Sbjct: 3644 TTSVTISEAGTAS-TLPVDTSTPVITSTQVSSSPVTPEG---TTMPIWTPSEGSTPLTTM 3699
Query: 742 PPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAP 801
P S S GS L S S+V + + TT + +A T + +++
Sbjct: 3700 PVSTTRVTSSE-GSTL--STPSVVTSTPV---TTSTEAISSSATLDSTTMSVSMPMEIST 3753
Query: 802 ATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMP 853
+ V + + T S+P V + S+ G P G MP
Sbjct: 3754 LGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMP 3805
Score = 80.9 bits (198), Expect = 5e-15
Identities = 148/683 (21%), Positives = 255/683 (37%), Gaps = 114/683 (16%)
Query: 284 TLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTI---DTSPPVDLFATASAAVPV 340
T EG + S +PL++ +TT+ + + T + DTS PV ++ AS++
Sbjct: 1026 TAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTT 1085
Query: 341 S--TSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEA 398
+ TS P+S +S G + P L+ + LS+ P +
Sbjct: 1086 ADGTSMPTST-------YSEGSTPLTSVPVSTR----------LVVSSEASTLSTTPVDT 1128
Query: 399 QISDPFAPEPTPPTTTAE---IATASASASTT-------TTVTAVTAEVDLFGDAFAASP 448
I + E + TTAE I T+ S TT +T V++E + S
Sbjct: 1129 SIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSK 1188
Query: 449 GEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEG-----SAEAAPELDLFAMKPPET 503
+ ++E ++ P PT ++ + + P + A+ E + P +T
Sbjct: 1189 TQVATSTEASSPP--PTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDT 1246
Query: 504 SVPVVTPTASTAPPVPATAPS-PAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALD 562
S PV T +++ P A S P + + T+ + T T+ A+T T P +D
Sbjct: 1247 STPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTP--VD 1304
Query: 563 IFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSV------ 616
G + S EV+++P P S+ ST + P + PV + + + +S+
Sbjct: 1305 TKGPVVTSN-EVSSSPTPAEGTSMPT-STYSEGRTPLTSIPVNTTLVASSAISILSTTPV 1362
Query: 617 --------DAFAAPSPAT---TASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSA 665
A SP T T+ P S G L ++ P +S+A++ S+
Sbjct: 1363 DNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTT---PVVSSEASTLSAT 1419
Query: 666 SADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLL 725
D G+ A + S T A+ + P + G TP S S P V + L
Sbjct: 1420 PVD--TSTPGTTSAEATSSPTTAE-GISIPTSTPSEGKTPLKSIPVSNTP-VANSEASTL 1475
Query: 726 MPTMAPAGQPAPVSMV---PPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQW 782
T + P S P+PA S A+ + + S A + ++ +S TT ++
Sbjct: 1476 STTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTA--LTSIPVSTTTVASSEINS 1533
Query: 783 NAGEKKLT-------GGANWQPKVA------PATWSAGVPP--SAPLQGAVPPTSSVPPV 827
+ +T A+ P A +T+S G P S P+ + +S +
Sbjct: 1534 LSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTL 1593
Query: 828 AGAP---------------SVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRP------ 866
+ P S G+ + G P++ PV P+ P
Sbjct: 1594 STTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVS-TTPVASPEASTLS 1652
Query: 867 ----PFGAAAVPGTQLSPSPTPA 885
+ + T++S SPTPA
Sbjct: 1653 TTPVDSNSPVITSTEVSSSPTPA 1675
Score = 80.9 bits (198), Expect = 5e-15
Identities = 136/637 (21%), Positives = 216/637 (33%), Gaps = 91/637 (14%)
Query: 265 PDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDT 324
P LT P S +TL + +P+ +SP T T +S+P T
Sbjct: 1631 PLLTSIPVSTTPVASPEASTL------------STTPVDSNSPVITSTEVSSSPTPAEGT 1678
Query: 325 SPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAP--PPPAGGATAWGDL 382
S P + + T + + P SS + + P P A
Sbjct: 1679 SMPTSTYTEGRTPLTSITVRTT-------PVASSAISTLSTTPVDNSTPVTTSTEARSSP 1731
Query: 383 LGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGD 442
+ + +S PSE P T P ++E +T SA+ T+T + E
Sbjct: 1732 TTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPT 1791
Query: 443 AFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPE 502
+ SEG P T TPV+ L A S E + P +
Sbjct: 1792 TAEGTSIPTSTLSEGMT-PLTSTPVSHTLVANS----------------EASTLSTTPVD 1834
Query: 503 TSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALD 562
++ PVVT TA ++ P PA S A + + + + +TTT +S + PA+
Sbjct: 1835 SNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAV- 1893
Query: 563 IFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASP---VPESSLTADLLSVDAF 619
STP V + ++P+ S+ S+P +G P +P S+ T
Sbjct: 1894 ------TSTP-VTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTT--------- 1937
Query: 620 AAPSPATTASPAKVDSSGVIDLFGDAFGS-----SASEPQPASQAASSSSASADLLAGFG 674
A S T S D+ + + A S S P PA S+ S L
Sbjct: 1938 VASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLV 1997
Query: 675 GSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQ 734
S A + S TP + T +TS+ S P+ G + T P+ +
Sbjct: 1998 VSSEASTLS-TTPVDTS-----------TPATTSTEGSSSPTTAGGTS---IQTSTPSER 2042
Query: 735 PAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGAN 794
P++ +P S + S G+ L S + ++ +T ++ +
Sbjct: 2043 TTPLAGMPVSTTLVVSSE-GNTL--STTPVDSKTQVTNSTEASSSATAEGSSMTISAPSE 2099
Query: 795 WQPKVA--PATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMM 852
P + P + + P A P S+ P + P +P GT M
Sbjct: 2100 GSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSP-----IPTEGTSMQTS 2154
Query: 853 PQQPVMFAQPMMRPPFGAAAVPGTQLSP-SPTPASQS 888
P+ P V + +S S TP S
Sbjct: 2155 TYSD--RRTPLTSMPVSTTVVASSAISTLSTTPVDTS 2189
Score = 78.2 bits (191), Expect = 3e-14
Identities = 104/485 (21%), Positives = 189/485 (38%), Gaps = 51/485 (10%)
Query: 303 SKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAA 362
S+++ +T S P+ T DTS P T V S PS + + SS A
Sbjct: 115 SRTTSESTSDSTTLFPSSTEDTSSP-----TTPEGTDVPMSTPSEESI------SSTMAF 163
Query: 363 AAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPT--PPTTTAEIATA 420
+ AP P A+ L + ++ + ++A S P PE T P +T +E +T
Sbjct: 164 VSTAPLP-----SFEAYTSLTYKVDMSTPLTTSTQAS-SSPTTPESTTIPKSTNSEGSTP 217
Query: 421 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF 480
S +T A + + L S +A ++ P + G+ P
Sbjct: 218 LTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPL 277
Query: 481 A--PSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTA 538
P + E + P T++PV+T T +++ P A S + +
Sbjct: 278 TRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLT 337
Query: 539 ATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPP 598
+T A+T TS + + P +++ V + +P + P+ ++ S+
Sbjct: 338 STPASTMPVATSEMSTLSITPV--------DTSTLVTTSTEPSSLPTTAEATSMLTSTLS 389
Query: 599 QGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQ 658
+G++P+ ++ L+ A S A+T S VDS + +A S + +
Sbjct: 390 EGSTPLTNMPVSTILV------ASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIA 443
Query: 659 AASSSSASADLLAGFGGSFMAPSPSPVTPAQ-NNLLQPNFEAAFGTTPSTSSSSSFDPSV 717
++ S S L + M S +PV ++ +NL ++ T ST +SSS +
Sbjct: 444 TSTPSEGSTPLTS------MPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAE 497
Query: 718 FDGLGDLLMPTMAPAGQPAPVSMVP----PSPAMAASKALGSDLDSSLASLVGNLGISGT 773
+ MPT P+ P++ + P + AS + +D+S + S +
Sbjct: 498 VNS-----MPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSS 552
Query: 774 TTKKG 778
TT +G
Sbjct: 553 TTPEG 557
Score = 75.9 bits (185), Expect = 2e-13
Identities = 119/567 (20%), Positives = 205/567 (36%), Gaps = 93/567 (16%)
Query: 265 PDLTQAPSSLMETLEQHLNTL-----EGKKPGN--NEGSGAPSPLSKSSPATTVTSPNST 317
P LT P S +NTL + + P ++ S +P+ +S T S ST
Sbjct: 1926 PPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGST 1985
Query: 318 PAKTIDTSPPVDLFATAS--AAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPP---P 372
P ++ S + + + AS + PV TS P++ + ++ G + P P
Sbjct: 1986 PLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTP 2045
Query: 373 AGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTA 432
G L+ LS+ P +++ T T + E ++++ + ++ T++A
Sbjct: 2046 LAGMPVSTTLVVSSEGNTLSTTPVDSK---------TQVTNSTEASSSATAEGSSMTISA 2096
Query: 433 VTAEVDLFGDA-FAASPGEAPAASEGAAAPA-TPTPVAAALDACSGNDPFA--------- 481
+ L + +P +P AS + P + +PV + + S P
Sbjct: 2097 PSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTY 2156
Query: 482 ----------PSEGSAEAAPELDLFAMKPPETSVPVV-------TPTASTAPPVPATAPS 524
P + A+ + + P +TS PV +PT S +P + PS
Sbjct: 2157 SDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPS 2216
Query: 525 PAPA-----------VAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPE 573
V + A+T +AT T+T T++ AT++P + S P
Sbjct: 2217 EGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAE-----GTSIPT 2271
Query: 574 VAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPAT-TASPAK 632
+ SI + T +S S P S T S +A + P A T+ P
Sbjct: 2272 STLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTS 2331
Query: 633 VDSSG--------VIDLFGDAFGSSASEPQPA---------SQAASSSSASADLLAGFGG 675
S G V +F +S PA SQA SS + + D
Sbjct: 2332 TSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTST 2391
Query: 676 SFMAPSPSPVTPAQNNLLQPNFEAAFGTTP-------STSSSSSFDPSVFDGLGDLLMPT 728
+P P + + + TTP +TS+ +S P+ +G +PT
Sbjct: 2392 YSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTS---IPT 2448
Query: 729 MAPAGQPAPVSMVPPSPAMAASKALGS 755
P+ P++ +P S S G+
Sbjct: 2449 SPPSEGTTPLASMPVSTTPVVSSEAGT 2475
Score = 72.8 bits (177), Expect = 1e-12
Identities = 136/654 (20%), Positives = 240/654 (36%), Gaps = 77/654 (11%)
Query: 300 SPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASA---AVPVST----SKPSSDLLDL 352
+P+ S+P T T S+P + TS P + S ++PVST + +S L
Sbjct: 2184 TPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSAT 2243
Query: 353 QPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSE---------AQISDP 403
D S+ + A + P A G + L E + L+S+P + +S
Sbjct: 2244 PVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGT-TPLTSIPVSHTLVANSEVSTLSTT 2302
Query: 404 FAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPAT 463
TP TT+ E ++ +A T+ T+ ++E + P ++ A+ T
Sbjct: 2303 PVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGN-------TPLTRMPVSTTMVASFET 2355
Query: 464 PTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAP 523
T D + ++ + S A + + E S P+ + ST P V + A
Sbjct: 2356 STLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEAS 2415
Query: 524 SPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPA---LDIFGDLFESTPEVAAAPKP 580
+ + + T +T A+++ TT + T+PP+ + +TP V++
Sbjct: 2416 THSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGT 2475
Query: 581 DAAPSID-----LFSTDAFSSP--------PQGASPVPESSLTADLLSVDAFAAPSPATT 627
+ +D ST+A SSP P + + LT+ +S A+P A+T
Sbjct: 2476 LSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPE-AST 2534
Query: 628 ASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTP 687
S VDS+ + + SSA+ + S S+ S + L S + S +
Sbjct: 2535 LSTTPVDSNSPV-VTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEAST 2593
Query: 688 AQNNLLQPNFEAAFGTTPSTSSSSSFDPS--------VFDGLGDLLMPTMAPAGQPAPVS 739
+ + T S+S +++ D S V L +L+ TM A A
Sbjct: 2594 LSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTL 2653
Query: 740 MVPP---------------SPAMAASKALGSDLDSSLASLVGNLGISGT---TTKKGDLQ 781
P SP A ++ + ++ + N+ +S T ++ L
Sbjct: 2654 STTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLS 2713
Query: 782 WNAGEKKLTGGANWQPKVAPAT-WSAGVPPSAPLQGAVPPTS---SVPPVAG--APSVGQ 835
+ + + +P T + S P G+ P TS S PVA A +V
Sbjct: 2714 TTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVST 2773
Query: 836 PGAGFGMP-PAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQS 888
+P T P + + P P + P T + + TP + S
Sbjct: 2774 TAVDTSIPVTTSTEASSSPTTAEVTSMPTSTP--SETSTPLTSMPVNHTPVASS 2825
Score = 60.5 bits (145), Expect = 7e-09
Identities = 100/460 (21%), Positives = 180/460 (39%), Gaps = 41/460 (8%)
Query: 292 NNEGSGAPSP-LSKSSPATTVTSPNSTPAK----TIDTSPPVDLFATASAAVPVSTSK-- 344
++EGS +P + S+P TT T S+ A T+ S P+++ +T + VST+
Sbjct: 3708 SSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEI-STLGTTILVSTTPVT 3766
Query: 345 --PSSDLLDLQPDFSSGGAAAAAAPAPPP---------PAGGATAWGDLLGEDSLAALSS 393
P S + ++S A+ + P P + LL ++ +S
Sbjct: 3767 RFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISV 3826
Query: 394 V-PSEAQ-ISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEA 451
+ PSEA +S P TP T+ + + S A TT ++T+E S
Sbjct: 3827 MSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVST-TL 3885
Query: 452 PAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSV--PVVT 509
P + GA+ +TP + S + P+ A + P T++ P
Sbjct: 3886 PTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTP 3945
Query: 510 PTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAA------TATTAPPALDI 563
T+STA PAT + + V + T +T++++TTT+ S TTA P +
Sbjct: 3946 VTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYV 4005
Query: 564 FGDLFESTPEVAAAPKPDAAPSIDLFST--DAFSSPPQGASPVPESSLTADLLSVDAFAA 621
STP + +A ++ ST + S + +P ESS + + S
Sbjct: 4006 TMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPT 4065
Query: 622 PSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPS 681
PA +++P +S + +A + + +P+++ S + + + P+
Sbjct: 4066 FPPAHSSTPPTTSASST-TVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPT 4124
Query: 682 PSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGL 721
+P P FG ++S + +DGL
Sbjct: 4125 STPTVPRTT--------TCFGDGCQNTASRCKNGGTWDGL 4156
Score = 56.6 bits (135), Expect = 1e-07
Identities = 116/538 (21%), Positives = 196/538 (36%), Gaps = 77/538 (14%)
Query: 392 SSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEA 451
SSV S+ PT TT+E + S + ++T + D ++P E
Sbjct: 96 SSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEE 155
Query: 452 PAASEGAAAPATPTPVAAALDACSGN-DPFAPSEGSAEAAPELDLFAMKPPETSVPVVTP 510
+S A P P A + + D P S +A+ P T++P T
Sbjct: 156 SISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSS----PTTPESTTIPKSTN 211
Query: 511 TASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAP-----PALDIFG 565
+ + P + P+ VA++ A T T +T T +A A+++P P+L
Sbjct: 212 SEGSTP--LTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSA 269
Query: 566 DLFESTP--------------EVAAAPKPDAAPSIDLF-STDAFSSPPQG-ASPVPESSL 609
STP E + AA +I + ST+A SSP + +P S+
Sbjct: 270 PSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTY 329
Query: 610 T---ADLLSVDAFAAP---SPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSS 663
T L S A P S +T S VD+S ++ ++++EP A ++
Sbjct: 330 TEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLV--------TTSTEPSSLPTTAEAT 381
Query: 664 SASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTP-------STSSSSSFDPS 716
S L+ +P P L+ + + T P +T+S +S P+
Sbjct: 382 SMLTSTLS------EGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPT 435
Query: 717 VFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTK 776
+ D + T P+ P++ +P S AS S+L++ + TT+
Sbjct: 436 TAE---DTSIATSTPSEGSTPLTSMPVSTTPVASSEA-----SNLSTTPVDSKTQVTTST 487
Query: 777 KGDLQWNAGEKKLTGGANWQPKVAPATWSAGVP----PSAPLQGAVPPTSSVPPVAGAPS 832
+ A T N P P+ S + + P+ + T S PV +
Sbjct: 488 E------ASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTP 541
Query: 833 V--GQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQS 888
V + P GT +P P + P+ P V ++ S + T + S
Sbjct: 542 VTTSSEASSSSTTPEGTSIP--TSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADS 597
>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
Length = 987
Score = 97.1 bits (240), Expect = 7e-20
Identities = 163/622 (26%), Positives = 234/622 (37%), Gaps = 90/622 (14%)
Query: 267 LTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSS--PATTVTSPNSTPAKTIDT 324
L APS + T + TL+ + + + APSP K S T TSP+S A +
Sbjct: 399 LIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASS 458
Query: 325 SPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPP--PPAGGATAWGDL 382
+ P+ P+ T+ P S+ P G + A AP+ P TA
Sbjct: 459 ASPM--------FKPIFTAPPKSEKEGPTP---PGPSVTATAPSSSSLPTTTSTTAPTFQ 507
Query: 383 LGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASA-STTTTVTAVTAEVDLFG 441
S+ +SVP A T PTTTA + T ASA S +T+ + D
Sbjct: 508 PVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTD--- 564
Query: 442 DAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF---APSEGSAEAAPEL-DLFA 497
PA G + ++ + A + + PF AP +A P + +F
Sbjct: 565 ------SASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQ 618
Query: 498 M-KPPETSVPVVTPTASTAPPVPATAPSPAPAVAA--AAAATTAATAAATTTTTTSAATA 554
KPP ++P T + + +P P+ + AA + +T AT+A T++ + +
Sbjct: 619 FGKPP--ALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFS 676
Query: 555 TTAPPALDI-FGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADL 613
T+ P +I FG +S + + P + P+ A PP A P S +
Sbjct: 677 NTSTPTFNIPFGSSAKS--PLPSYPGANPQPAFGA----AEGQPPGAAKPALTPSFGSSF 730
Query: 614 LSVDAFAAPSPATTASPA-----KVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASAD 668
++ AAP+PAT +PA K+ + V FG + AS+ A A
Sbjct: 731 TFGNS-AAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPAS 789
Query: 669 LLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSF-----DPSVFDGLGD 723
FGGS S T + F A T S SSSS F P F G
Sbjct: 790 SQPAFGGSTAVFSFGAATSS-------GFGATTQTASSGSSSSVFGSTTPSPFTFGG--- 839
Query: 724 LLMPTMAPAGQPAPVSMV--PPSPAMAASKALGSDLDSSLAS---LVGNLGIS--GTTTK 776
+ APAG + V P S A + + G+ S A+ G LG + GTT +
Sbjct: 840 ----SAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQ 895
Query: 777 KGDLQWNAG---EKKLTGGANWQPKVAPATWSAGV----------PPSAPLQGAVPPTSS 823
+N G E K G P T + GV SAP QG V
Sbjct: 896 STPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFV----G 951
Query: 824 VPPVAGAPSVGQPGAGFGMPPA 845
V P A GAG P A
Sbjct: 952 VGPFGSAAPSFSIGAGSKTPGA 973
Score = 93.6 bits (231), Expect = 8e-19
Identities = 183/720 (25%), Positives = 256/720 (35%), Gaps = 169/720 (23%)
Query: 271 PSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDL 330
P+SL+ L LE K S P P S + T SP TP+ PP+ L
Sbjct: 321 PTSLLAPSTNPL--LESLKKMQTPPSLPPCPESAGAATTEALSPPKTPS----LLPPLGL 374
Query: 331 FATASAAV---PVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDS 387
+ + P SKP + LL L P S A AP P A AT +
Sbjct: 375 SQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAP-PTLQAETATK------PQA 427
Query: 388 LAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAAS 447
+A S P ++ + F + T P++ A A +SAS +F F A
Sbjct: 428 TSAPSPAPKQSFL---FGTQNTSPSSPAAPAASSAS--------------PMFKPIFTAP 470
Query: 448 PGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPV 507
P + EG PTP ++ A + + P+ S A +F+ P SVP+
Sbjct: 471 P---KSEKEG------PTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPL 521
Query: 508 VTPTASTAPPVPATAP-SPAPAVAAAAAATTA------------------------ATAA 542
P PATAP + AP A+AT+A + ++
Sbjct: 522 PAPFFKQT-TTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSS 580
Query: 543 ATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAP------------KPDAAPSIDLFS 590
++ +TTTS ATA + P +FG P+ +AA KP A P+ +
Sbjct: 581 SSVSTTTSTATAASQP---FLFG-----APQASAASFTPAMGSIFQFGKPPALPTTTTVT 632
Query: 591 TDAFSSPPQGASPVPESSLTADLLSV-DAFAAPSPATTASPAKVDSSGVIDLFGDAFGSS 649
T FS A P SS AD A +PAT++ P S+ F FGSS
Sbjct: 633 T--FSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSS 690
Query: 650 A---------SEPQPASQAASS---SSASADLLAGFGGSF-----------MAPSPSP-- 684
A + PQPA AA +A L FG SF AP+P+P
Sbjct: 691 AKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPAS 750
Query: 685 ---VTPAQ-NNLLQPNF----EAAFGTTPSTSSSS----------------SFDPSVFDG 720
+ PA +QP F +AFG + S+ SF + G
Sbjct: 751 TIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSG 810
Query: 721 LGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDL 780
G T + + PSP GS + S N+ G++ G
Sbjct: 811 FG-ATTQTASSGSSSSVFGSTTPSPFTFG----GSAAPAGSGSFGINVATPGSSATTGAF 865
Query: 781 QWNAGEKKLTGGANWQPKVAPATWSAG------VPPSAPLQGAVPPTSSVPPVAG---AP 831
+ AG+ T + P T G S P V T+ PV G P
Sbjct: 866 SFGAGQSGSTATS------TPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATP 919
Query: 832 SVGQ----PGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQ 887
+ GQ PG G G P Q + PFG+AA + + S TP ++
Sbjct: 920 TFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGV-----GPFGSAAPSFSIGAGSKTPGAR 974
Score = 82.4 bits (202), Expect = 2e-15
Identities = 154/636 (24%), Positives = 232/636 (36%), Gaps = 100/636 (15%)
Query: 299 PSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPS-----SDLLDLQ 353
PS SSPA++ + PAK I +L +S++ P++ K S +D +
Sbjct: 167 PSSSPFSSPASSRSQTPERPAKKIREE---ELCHHSSSSTPLAADKESQGEKAADTTPRK 223
Query: 354 PDFSSGGAAAAAA------------------PAPPPPAGGATAWGDLLGEDSLAALSSVP 395
S+ + ++ PPPP G + + L + A+L
Sbjct: 224 KQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFN 283
Query: 396 SEAQISDPFAPEP---TPPTTTAEIA---TASASASTTTTVTAVTAEVDLFGDAFAASPG 449
+ A TPPTT A+A+AS T++ A + L +P
Sbjct: 284 QALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPP 343
Query: 450 EAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVT 509
P E A A T +A S P PS P L L PP + +
Sbjct: 344 SLPPCPESAGAATT--------EALS--PPKTPS-----LLPPLGLSQSGPPGL---LPS 385
Query: 510 PTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFE 569
P+ + PP PAP++ A T A T T A +A + P
Sbjct: 386 PSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQN 445
Query: 570 STPEVAAAPKPDAAPSIDLFSTDAFSSPP----QGASPVPESSLTADLLSVDAFAAPSPA 625
++P AAP AA S F++PP +G +P P S+TA S + +
Sbjct: 446 TSPSSPAAP---AASSASPMFKPIFTAPPKSEKEGPTP-PGPSVTATAPSSSSLPTTTST 501
Query: 626 TTASPAKVDSSGVIDLFGDAFGSSASEPQPA------SQAASSSSASADLLAGFGGSFMA 679
T + V SS G AS P PA + A++ + +A L G + A
Sbjct: 502 TAPTFQPVFSS---------MGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSA 552
Query: 680 PSP-SPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPV 738
+P + +P+ ++ +P F FG +SSS S S P + A Q +
Sbjct: 553 VAPITSASPSTDSASKPAF--GFGINSVSSSSVSTTTSTATAASQ---PFLFGAPQASAA 607
Query: 739 SMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPK 798
S +PAM + G + V S T +A + +G +
Sbjct: 608 SF---TPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAAD--FSGFGSTLAT 662
Query: 799 VAPATWSAGVPPSAPLQGAVPPTSSVP--PVAGAPSVGQPGAGFGMPPAGTGMPMMPQQP 856
APAT S P+ PT ++P A +P PGA P G QP
Sbjct: 663 SAPATSSQ---PTLTFSNTSTPTFNIPFGSSAKSPLPSYPGAN-PQPAFGAA----EGQP 714
Query: 857 VMFAQPMMRPPFGA------AAVPGTQLSPSPTPAS 886
A+P + P FG+ +A P +P+P PAS
Sbjct: 715 PGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPAS 750
Score = 77.4 bits (189), Expect = 6e-14
Identities = 142/575 (24%), Positives = 197/575 (34%), Gaps = 116/575 (20%)
Query: 296 SGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPD 355
S A S +P TT S T SPP L A ++ + S K + L P
Sbjct: 290 SDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPP-SLPPC 348
Query: 356 FSSGGAAAAAAPAPP------PPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPT 409
S GAA A +PP PP G L + L PS +
Sbjct: 349 PESAGAATTEALSPPKTPSLLPPLG--------LSQSGPPGLLPSPSF---------DSK 391
Query: 410 PPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAA 469
PPTT + A + T T T + + A A + +P P +
Sbjct: 392 PPTTLLGLIPAPSMVPATDTKAPPTLQAET-------------ATKPQATSAPSPAPKQS 438
Query: 470 ALDACSGNDPFAPSEGSAEAA-PELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPA 528
L P +P+ +A +A P PP++ TP P V ATAPS
Sbjct: 439 FLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPG---PSVTATAPS---- 491
Query: 529 VAAAAAATTAATAAATTTTTTSAATATTAPPA-LDIFGDLFESTPEVAAAPKPDAAPSID 587
+++ T +TT T ++ PPA + + F+ T A AP A
Sbjct: 492 ------SSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTG 545
Query: 588 LFSTDAFSSPPQGASPVPES-SLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAF 646
L S + +P ASP +S S A +++ ++ S +TT S A S LFG
Sbjct: 546 LASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPF--LFG--- 600
Query: 647 GSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPS 706
P + AAS + A + FG P+ + VT +L P+
Sbjct: 601 -------APQASAASFTPAMGSIFQ-FGKPPALPTTTTVTTFSQSLPT--------AVPT 644
Query: 707 TSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVG 766
+SSS+ D F G G L T APA P + + GS S L S
Sbjct: 645 ATSSSAAD---FSGFGSTL-ATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSY-- 698
Query: 767 NLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPP------ 820
GAN QP A G PP A P
Sbjct: 699 ------------------------PGANPQPAFGAA---EGQPPGAAKPALTPSFGSSFT 731
Query: 821 --TSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMP 853
S+ P A AP+ P + + PA P+ P
Sbjct: 732 FGNSAAPAPATAPTPA-PASTIKIVPAHVPTPIQP 765
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 94.4 bits (233), Expect = 4e-19
Identities = 150/623 (24%), Positives = 209/623 (33%), Gaps = 134/623 (21%)
Query: 288 KKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPP-------VDLFATASAAVPV 340
+ P + G AP P +SP P S+P + T+ P + + A + A
Sbjct: 93 RPPASGRGERAP-PAKNTSPG-----PVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 146
Query: 341 STSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQI 400
+T P L S+G + P P P+ G + +P A
Sbjct: 147 ATEAPKRSAL------SAGARRDTSGPTPGTPSPAMARRSRAAGTEV-----GLPRPAP- 194
Query: 401 SDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAA 460
+ P PPT + +SAS +TT + +A G AS ++
Sbjct: 195 ----SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP------SAGGGLQRPASRSLSS 244
Query: 461 PATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPV--VTPTASTAPPV 518
ATP A + P AP+ S L A++PP+ + P P
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ--ALRPPQVTPPRKDAAPALGPLSSS 302
Query: 519 PATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAP 578
P PSP+ A+ + A T AT +++ T A APP+ + P + P
Sbjct: 303 PLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPS-------APPSLQTLP 355
Query: 579 KPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGV 638
P A P +T + SP A+ S L + LS A P P A PA
Sbjct: 356 SPPATPPSQ--ATTSLGSPTLQAT---HSFLPSPPLS--PLATPPPQ--APPALA----- 401
Query: 639 IDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFE 698
P QA S AS L +P +P A N L +
Sbjct: 402 ---------------LPPLQAPPSPPASPPL---------SPLATPSPQAPNALAVHLLQ 437
Query: 699 AAFGTTPSTSSSSSFDPSVFDGLG-DLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDL 757
A F PS + F P + P+ AP AP VPPSP +
Sbjct: 438 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP------- 490
Query: 758 DSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGA 817
+ S T + P AP A PP AP A
Sbjct: 491 ----------MSPSATPPPQAP----------------PPLAAPPLQLAKPPPQAPPALA 524
Query: 818 VPPTSSVP-PVAGAPSVG--QPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVP 874
PP ++P P A P P A M P T P P PV+ A + PP
Sbjct: 525 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP--PVLAAPLLQVPP------- 575
Query: 875 GTQLSPSPTPASQSPKKPPAKDP 897
SP +P Q+P++PP P
Sbjct: 576 ----SPPASPTLQAPRRPPTPGP 594
Score = 78.6 bits (192), Expect = 2e-14
Identities = 147/647 (22%), Positives = 213/647 (32%), Gaps = 122/647 (18%)
Query: 285 LEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSK 344
++ K+ G+ A +P +++ P P +P +P A+ AV K
Sbjct: 1 MDNKRDKAKAGAAARTPAARA-PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVG---RK 56
Query: 345 PSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPF 404
P ++ +GG A P P AG + G S S P+ +
Sbjct: 57 PLAE--------RAGGIGGATIPESAPRAGPTRS----AGTSSRNPASRPPASGR----- 99
Query: 405 APEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATP 464
E PP T+ S+ + T L S E A + AP
Sbjct: 100 -GERAPPAKN----TSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 154
Query: 465 TPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPS 524
A A SG P PS A + + T V + P S P P P
Sbjct: 155 ALSAGARRDTSGPTPGTPSPAMARRS--------RAAGTEVGLPRPAPSARPRPPTEGPR 206
Query: 525 PAPAVAAAAAATTAATAAA------------TTTTTTSAATATTAPPALDIFGDLFESTP 572
+ + A+ + T + AA + + +S+AT ++P S P
Sbjct: 207 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA---------RSGP 257
Query: 573 EVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTAS--- 629
P+ A PS PPQ P +++ LS A PSP+
Sbjct: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQA 317
Query: 630 ----PAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPV 685
PA SS + + P P + + S+ S L +P +P
Sbjct: 318 PPTLPATPHSSSLT--------CQLATPLPLAPPSPSAPPSLQTLP-------SPPATPP 362
Query: 686 TPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSP 745
+ A +L P +A PS S P P AP P PPSP
Sbjct: 363 SQATTSLGSPTLQATHSFLPSPPLSPLATP-----------PPQAPPALALPPLQAPPSP 411
Query: 746 -AMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATW 804
A L + + +L +L LQ A + P +P
Sbjct: 412 PASPPLSPLATPSPQAPNALAVHL-----------LQ-----------APFSPPPSPPVQ 449
Query: 805 SAGVPP-SAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPM 863
+ PP S P+ + P S PP AP + P + PP PQ P A P
Sbjct: 450 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 509
Query: 864 MR----PPFG--AAAVPGTQLSPSPTPAS---QSPKKPPAKDPLADL 901
++ PP A A P Q PSP PAS Q+P P A P++ L
Sbjct: 510 LQLAKPPPQAPPALATPPLQALPSP-PASFPGQAPFSPSASLPMSPL 555
Score = 78.6 bits (192), Expect = 2e-14
Identities = 117/472 (24%), Positives = 174/472 (36%), Gaps = 91/472 (19%)
Query: 299 PSPLSKSSPAT-----TVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQ 353
P PL+ SP+ T+ SP +TP TS + +P S P S L
Sbjct: 337 PLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP---SPPLSPLATPP 393
Query: 354 PDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTT 413
P A A P PP+ A+ L S A +++ + PF+P P+PP
Sbjct: 394 PQ---APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL-LQAPFSPPPSPPVQ 449
Query: 414 TAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDA 473
AS S + T P +AP + P+P A+ +
Sbjct: 450 APFSPPASPPVSPSAT-----------------PPSQAPPSLAAPPLQVPPSPPASPPMS 492
Query: 474 CSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAA 533
S P P AAP L L A PP+ + TP P PA+ P AP
Sbjct: 493 PSATPP--PQAPPPLAAPPLQL-AKPPPQAPPALATPPLQALPSPPASFPGQAP------ 543
Query: 534 AATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDA 593
+ +A+ + A APP L + P + P P A+P++
Sbjct: 544 -----FSPSASLPMSPLATPPPQAPPVL--------AAPLLQVPPSPPASPTL------- 583
Query: 594 FSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEP 653
+P + +P P++S++ L++ P P + SP+ S DL G + S+ S P
Sbjct: 584 -QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP--DLAGHS-SSATSTP 639
Query: 654 Q--------PASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGT-- 703
+ P AA+S A+L A ++ S P P F A G
Sbjct: 640 EELRGYDSGPEGGAAASPPPDAELAACHPAAW---SRGPAPPLA-------FRGAPGAPL 689
Query: 704 --TPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVP-PSPAMAASKA 752
P+T S+ DGL + + PAP ++ P PSP + KA
Sbjct: 690 PWPPATGPGSA------DGLCTIYETEGPESATPAPGALDPGPSPGTSGGKA 735
Score = 53.9 bits (128), Expect = 7e-07
Identities = 70/276 (25%), Positives = 105/276 (38%), Gaps = 34/276 (12%)
Query: 299 PSPLSKSSPATTVTSPNSTPAKTID---TSPPVDLFATASAAVPVSTSKPSSDL------ 349
P + S PA+ SP++TP +PP+ L A P + P L
Sbjct: 478 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS 537
Query: 350 LDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLL-------GEDSLAALSSVPS---EAQ 399
Q FS + + A PPP LL +L A P+ +
Sbjct: 538 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 597
Query: 400 ISDP-----FAPEPTPPTTTAEIATASAS--ASTTTTVTAVTAEVDLF-----GDAFAAS 447
+S P AP P PP + + +T S A +++ T+ E+ + G A A+
Sbjct: 598 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP 657
Query: 448 PGEAP-AASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVP 506
P +A AA AA P P A A P+ P+ G A ++ + PE++ P
Sbjct: 658 PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 717
Query: 507 VVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAA 542
P A P P T+ A A A A A++ + A
Sbjct: 718 --APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQA 751
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 91.7 bits (226), Expect = 3e-18
Identities = 165/731 (22%), Positives = 243/731 (33%), Gaps = 170/731 (23%)
Query: 268 TQAPSSLMETLEQHLNTLEG----KKPGNNEGSGAPSPLSKSSPATTVTSP--------- 314
T+ P + + +H T ++P G P+ S SS AT ++SP
Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 261
Query: 315 --------------------------------------NSTPAKTIDTS-------PPVD 329
+S+P T S PP D
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321
Query: 330 LFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPP--PP--AGGATAWGDLLGE 385
AT A + S P + L L P S + P+PP PP A + +
Sbjct: 322 NAATPLPAT-LPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP 380
Query: 386 DSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTT-------TTVTAVTAEVD 438
SL + + ++ P P P + + ++ S T T++ +
Sbjct: 381 PSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQAS 440
Query: 439 LFGDAFAAS-PGEAPAASEGAAAPATP------TPVAAALDACSGNDPFAPSEGSAEAAP 491
L + AS P ++P + PA+P +P + L + P A +P
Sbjct: 441 LTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSP 500
Query: 492 E--LDLFAMKPPETSVPVVTPTASTAPPVPATAP--------SPAPAVAAAAAATT---- 537
+ L M P ET + P+ T PP T P +P P A+A TT
Sbjct: 501 QAPLSSLIMPPLETQSSLAPPSLQT-PPASLTTPPLENLPSLAPPPLQTASAPLTTPHLE 559
Query: 538 AATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSP 597
A + TT PP TP A P P A P++ SP
Sbjct: 560 TPPCPAPCPLQAPPSPLTTPPP----------ETPSSIATPPPQAPPALASPPLQGLPSP 609
Query: 598 PQG--ASPVPESSLTADLLSVDAFAAP------SPATTASPAKVDSSGVIDLFGDAFGSS 649
P A+P P++ L + A +P SP T SP + ++ + L F
Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP-QAPNALAVHLLQAPF--- 665
Query: 650 ASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSS 709
+ P P QA S AS ++PS +P + A +L P + PS +
Sbjct: 666 SPPPSPPVQAPFSPPASPP---------VSPSATPPSQAPPSLAAPPLQ----VPPSPPA 712
Query: 710 SSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLG 769
S PS P AP AP VPPSP + + + + L+
Sbjct: 713 SPPMSPSA-------TPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765
Query: 770 ISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVP-PVA 828
+ + P P + A PP AP A PP ++P P A
Sbjct: 766 LQVPPS--------------------PPASLPMSPLAKPPPQAPPALATPPLQALPSPPA 805
Query: 829 GAPSVG--QPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPAS 886
P P A M P T P P PV+ A + PP SP +P
Sbjct: 806 SFPGQAPFSPSASLPMSPLATPPPQAP--PVLAAPLLQVPP-----------SPPASPTL 852
Query: 887 QSPKKPPAKDP 897
Q+P++PP P
Sbjct: 853 QAPRRPPTPGP 863
Score = 87.0 bits (214), Expect = 7e-17
Identities = 146/657 (22%), Positives = 244/657 (37%), Gaps = 80/657 (12%)
Query: 293 NEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDL 352
+ +G L + +P+ P P K++ ++ + + P + +PS+
Sbjct: 180 SRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE----HSTTEPSPAARRRPSAGGGLQ 235
Query: 353 QPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPT 412
+P +S +++A P P G +A G A S P + P+ TPP
Sbjct: 236 RP--ASRSLSSSATPLSSPARSGPSA----RGTPRAPAHPSQPKPKGLQALRPPQVTPPR 289
Query: 413 TTAEIATASASASTTTTVT-AVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAAL 471
A A S+S T + + T + AA+P PA + ATP P+A
Sbjct: 290 KDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATP--LPATLPPSPPLATPLPLAPPS 347
Query: 472 DACSGND---PFAPSEGSAEAAPELDLFAMKPP---ETSVPVVTPTAST-----APPVP- 519
+ + P P+ ++A P + M+ P +T P+ P + T APP P
Sbjct: 348 PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPL 407
Query: 520 ------ATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDL-FESTP 572
AT +P + A + T + + T+ + A+T P + + L ++P
Sbjct: 408 ALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASP 467
Query: 573 EVAAAPKPDAAP---SIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTAS 629
+ + P +P + + A SS + P SSL L + AP P+
Sbjct: 468 PLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP-PSLQTP 526
Query: 630 PAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQ 689
PA + + + +L P+ +ASA L + P+P P+
Sbjct: 527 PASLTTPPLENL-------------PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP 573
Query: 690 NNLLQPNFE--AAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPP---- 743
+ L P E ++ T P + + P + L P P Q P +PP
Sbjct: 574 SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAP 633
Query: 744 -----SPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPK 798
SP ++ ++LA + S + ++ + P
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 693
Query: 799 VAPATWSAG---VPPSAPLQ-----GAVPPTSSVPPVAGAP--SVGQPGAGFGMPPAGTG 848
AP + +A VPPS P A PP + PP+A P P A M P+ T
Sbjct: 694 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP 753
Query: 849 MPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSP--------TPASQSPKKPPAKDP 897
P +P P++ A P+ PP A++P + L+ P TP Q+ PPA P
Sbjct: 754 PPRVP--PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFP 808
Score = 84.0 bits (206), Expect = 6e-16
Identities = 171/642 (26%), Positives = 226/642 (35%), Gaps = 123/642 (19%)
Query: 302 LSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTS-----KPSSDLLDLQP-- 354
+S ++TSP S PA T SPP+ + A+ P+ TS P S L + P
Sbjct: 432 MSPRQTQASLTSP-SRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQ 490
Query: 355 DFSSGGAAAAAAP---------------APP----PPAGGATAWGD---LLGEDSLAALS 392
SS + + AP APP PPA T + L L S
Sbjct: 491 ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTAS 550
Query: 393 SVPSEAQISDPFAPEPTP------PTTTAEIATASASASTTTTVTAVTAEVDLFG----- 441
+ + + P P P P P TT T S+ A+ A L G
Sbjct: 551 APLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPP 610
Query: 442 -DAFAASPGEAPAASEGAAAPATPTPVAAA-LDACSGNDPFAPSEGSAEAAPELDLFAMK 499
A P +AP A P+P A+ L + P AP+ + L A
Sbjct: 611 LSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL-----LQAPF 665
Query: 500 PPETSVPVVTPTASTA-PPVP--ATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATT 556
P S PV P + A PPV AT PS AP AA + A+ + SA
Sbjct: 666 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725
Query: 557 APPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDA------FSSPPQGASPVPESSLT 610
APP L + P + P P A+P + +T ++PP P P +SL
Sbjct: 726 APPPL--------AAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP 777
Query: 611 ADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDA-FGSSASEPQPASQAASSSSASADL 669
L+ AP PA P + S G A F SAS P S A+ + +
Sbjct: 778 MSPLAKPPPQAP-PALATPPLQALPSPPASFPGQAPFSPSASLPM--SPLATPPPQAPPV 834
Query: 670 LAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTM 729
LA + PSP PA L P G P TS S P +
Sbjct: 835 LAA---PLLQVPPSP--PASPTLQAPRRPPTPG--PDTSVSG---------------PRL 872
Query: 730 APAGQPAPVSMVPPSPAMAASKAL-GSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKK 788
A P P PP P+ + S L G DL +S T+T + +++G +
Sbjct: 873 TLALAPGP----PPPPSRSPSSTLSGPDLAGHSSS--------ATSTPEELRGYDSGPE- 919
Query: 789 LTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTG 848
GGA +A PP A L P S P G PGA PPA TG
Sbjct: 920 --GGA-----------AASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA-TG 965
Query: 849 MPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPK 890
++ P A PG L P P+P + K
Sbjct: 966 PGSADGLCTIYE---TEGPESATPAPGA-LDPGPSPGTSGGK 1003
Score = 77.8 bits (190), Expect = 4e-14
Identities = 121/496 (24%), Positives = 181/496 (36%), Gaps = 97/496 (19%)
Query: 299 PSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSS 358
P+P +P + +T+P +I T PP A AS + S P S L P
Sbjct: 564 PAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPP 623
Query: 359 GGA-----AAAAAPAPPPPAGGATAWG---DLLGEDSLAALSSVPSEAQISDPFAPEPTP 410
A A + PA PP + AT + L L A S P + PF+P +P
Sbjct: 624 XLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 683
Query: 411 PTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAP--------- 461
P + + + A S V ASP +P+A+ AP
Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQVPPSPP-------ASPPMSPSATPPPQAPPPLAAPPLQ 736
Query: 462 ATPTPVAAALDACSGNDPFAPSEGSAEAAPELDL------------FAMKPPETSVPVVT 509
P+P A+ + S P P AAP L + A PP+ + T
Sbjct: 737 VPPSPPASPPMSPSATPP--PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT 794
Query: 510 PTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFE 569
P P PA+ P AP + +A+ + A APP L
Sbjct: 795 PPLQALPSPPASFPGQAP-----------FSPSASLPMSPLATPPPQAPPVL-------- 835
Query: 570 STPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTAS 629
+ P + P P A+P++ +P + +P P++S++ L++ P P + S
Sbjct: 836 AAPLLQVPPSPPASPTL--------QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 887
Query: 630 PAKVDSSGVIDLFGDAFGSSASEPQ--------PASQAASSSSASADLLAGFGGSFMAPS 681
P+ S DL G + S+ S P+ P AA+S A+L A ++ S
Sbjct: 888 PSSTLSGP--DLAGHS-SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW---S 941
Query: 682 PSPVTPAQNNLLQPNFEAAFGT----TPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAP 737
P P F A G P+T S+ DGL + + PAP
Sbjct: 942 RGPAPPLA-------FRGAPGAPLPWPPATGPGSA------DGLCTIYETEGPESATPAP 988
Query: 738 VSMVP-PSPAMAASKA 752
++ P PSP + KA
Sbjct: 989 GALDPGPSPGTSGGKA 1004
Score = 66.2 bits (160), Expect = 1e-10
Identities = 158/672 (23%), Positives = 214/672 (31%), Gaps = 155/672 (23%)
Query: 366 APAPPPPAGGAT----AWGDLLGEDSLAALSSVPSEAQISDPFAPE--PTPPTTTAEIAT 419
+P PPPP A +G LA + A I + AP PT T+
Sbjct: 32 SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES-APRAGPTRSAGTSSRNP 90
Query: 420 ASASASTTTTVTAVTAEVDLFGDAFAASPGEA-------PAASEG---------AAAPAT 463
AS ++ A A+ G +SPG A P +G A AT
Sbjct: 91 ASRPPASGRGERAPPAKNTSPGPV--SSPGRASGTTRPGPLGQKGLRISAEETVARGKAT 148
Query: 464 PTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPV----- 518
P +AL A + D P+ G+ A A E +P P+A PP
Sbjct: 149 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA-AGTEVGLPRPAPSARPRPPTEGPRK 207
Query: 519 --------PATAPSPA-------------PAVAAAAAATTAATAAATTTTTTSAATATTA 557
T PSPA PA + +++ T ++ A + + A
Sbjct: 208 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 267
Query: 558 PPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSP-PQG--ASPVP-----ESSL 609
P+ L P P+ DAAP++ S+ ++P P G A PVP + L
Sbjct: 268 HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPL 327
Query: 610 TADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSA------------------- 650
A L A P P SP+ S + S A
Sbjct: 328 PATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP 387
Query: 651 ------SEPQPASQAASSSSASADLLA--GFGG-------SFMAPSP--------SPVTP 687
S P+ QA S A + L A G SF+ SP SP P
Sbjct: 388 PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP 447
Query: 688 AQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDL------LMPTMAPAGQPAPVSMV 741
A P +A S +S P+V L + ++A AP+S +
Sbjct: 448 ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSL 507
Query: 742 PPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQ----- 796
P S L + ASL TT +L A T A
Sbjct: 508 IMPPLETQSSLAPPSLQTPPASL--------TTPPLENLPSLAPPPLQTASAPLTTPHLE 559
Query: 797 --------PKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTG 848
P AP + PP P A PP + P +A P G P PP
Sbjct: 560 TPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPS-----PPLSPL 614
Query: 849 MPMMPQQPVMFAQPMMR--------PPFGAAAVPGTQ-------------LSPSPTPASQ 887
PQ P A P ++ PP A P Q SP P+P Q
Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674
Query: 888 SPKKPPAKDPLA 899
+P PPA P++
Sbjct: 675 APFSPPASPPVS 686
Score = 58.2 bits (139), Expect = 3e-08
Identities = 148/623 (23%), Positives = 200/623 (32%), Gaps = 131/623 (21%)
Query: 403 PFAPEPTPPTTTAEIATASA--------------------------------SASTTTTV 430
P +P P PP T A + A SA T++
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRN 89
Query: 431 TAVTAEVDLFGD----AFAASPG--EAPAASEGAAAP--------------------ATP 464
A G+ A SPG +P + G P AT
Sbjct: 90 PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 149
Query: 465 TPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPV------ 518
P +AL A + D P+ G+ A A E +P P+A PP
Sbjct: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSRA-AGTEVGLPRPAPSARPRPPTEGPRKS 208
Query: 519 -------PATAPSPA-------------PAVAAAAAATTAATAAATTTTTTSAATATTAP 558
T PSPA PA + +++ T ++ A + + A
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268
Query: 559 PALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSP-PQG--ASPVP-----ESSLT 610
P+ L P P+ DAAP++ S+ ++P P G A PVP + L
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLP 328
Query: 611 ADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSA--SEPQPASQAASSSSASAD 668
A L A P P SP+ S + S A S P QA S
Sbjct: 329 ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPP 388
Query: 669 LLAGFGGSFMAPS-PSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDP-SVFDGLGDLLM 726
+ S +PS +P +P + LQ T +T S + P L
Sbjct: 389 IQVPH--SLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSR 446
Query: 727 PTMAPAGQP---APVSMVPPSPAMAAS-----KALGSDLD-------SSLASLVGNLGIS 771
P P P AP+S+ P SP + S L S L SSLAS +S
Sbjct: 447 PASTPPDSPPLQAPLSL-PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS 505
Query: 772 GTTTKKGDLQWNAGEKKL-TGGANWQPKVAPATWSAGVPP----SAPLQGAVPPTSSVPP 826
+ Q + L T A+ S PP SAPL P PP
Sbjct: 506 SLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPL---TTPHLETPP 562
Query: 827 VAGAPSVGQPGAGFGMPPAGTGMPMM---PQQPVMFAQPMMR----PPFGAAAVPGTQLS 879
+ P + PP T + PQ P A P ++ PP A P Q
Sbjct: 563 CPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAP 622
Query: 880 PS-PTPASQSPKKPPAKDPLADL 901
P P Q+P PPA PL+ L
Sbjct: 623 PXLALPPLQAPPSPPASPPLSPL 645
Score = 50.8 bits (120), Expect = 6e-06
Identities = 70/269 (26%), Positives = 103/269 (38%), Gaps = 38/269 (14%)
Query: 299 PSPLSKSSPATTVTSPNSTP---AKTIDTSPPVDLFATASAAVP------VSTSKPSSDL 349
P + S PA+ SP + P A +PP+ + A+ P S S P S L
Sbjct: 765 PLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 824
Query: 350 LDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPS---EAQISDP--- 403
P AA P PPA +L A P+ + +S P
Sbjct: 825 ATPPPQAPPVLAAPLLQVPPSPPAS-----------PTLQAPRRPPTPGPDTSVSGPRLT 873
Query: 404 --FAPEPTPPTTTAEIATASAS--ASTTTTVTAVTAEVDLF-----GDAFAASPGEAP-A 453
AP P PP + + +T S A +++ T+ E+ + G A A+ P +A A
Sbjct: 874 LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA 933
Query: 454 ASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTAS 513
A AA P P A A P+ P+ G A ++ + PE++ P P A
Sbjct: 934 ACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP--APGAL 991
Query: 514 TAPPVPATAPSPAPAVAAAAAATTAATAA 542
P P T+ A A A A A++ + A
Sbjct: 992 DPGPSPGTSGGKAAAGAGAGASSRSPKQA 1020
Score = 48.9 bits (115), Expect = 2e-05
Identities = 97/391 (24%), Positives = 136/391 (34%), Gaps = 62/391 (15%)
Query: 517 PVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFEST-PEVA 575
P P +P P P V AA AA A P + G + +T PE
Sbjct: 27 PRPPGSPRPPPPVTPAA------------LRVLGAAGAVGRKPLAERAGGIGGATIPE-- 72
Query: 576 AAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDS 635
+AP+ S S + S PP A A PAK S
Sbjct: 73 SAPRAGPTRSAGTSSRNPASRPP----------------------ASGRGERAPPAKNTS 110
Query: 636 SGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQP 695
G + G A G+ + P P Q SA + G + P ++ L
Sbjct: 111 PGPVSSPGRASGT--TRPGPLGQKGLRISAEETVARG---------KATEAPKRSALSAG 159
Query: 696 NFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGS 755
G TP T S + S G ++ +P AP+ +P P + P +AS+ +
Sbjct: 160 ARRDTSGPTPGTPSPAMARRSRAAGT-EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218
Query: 756 DLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAP-- 813
+ S A + G G + ++ L+ A P A T A PS P
Sbjct: 219 E-PSPAARRRPSAG--GGLQRPASRSLSSSATPLSSPARSGPS-ARGTPRAPAHPSQPKP 274
Query: 814 --LQGAVPPTSSVPPVAGAPSVGQ-PGAGFGMP-PAGT-GMPMMPQQPVMFAQPMMRPPF 868
LQ PP + P AP++G + P P+GT P+ P P PP
Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPS 334
Query: 869 GAAAVPGTQLSPSPT--PASQSPKKPPAKDP 897
A P PSP+ P+ Q+ PPA P
Sbjct: 335 PPLATPLPLAPPSPSAPPSLQTLPSPPATPP 365
>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
sapiens]
Length = 834
Score = 91.7 bits (226), Expect = 3e-18
Identities = 161/617 (26%), Positives = 237/617 (38%), Gaps = 90/617 (14%)
Query: 267 LTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSS--PATTVTSPNSTPAKTIDT 324
L APS + T + TL+ + + + APSP K S T TSP+S A +
Sbjct: 248 LIPAPSMVPATDTKAPPTLQAETTTKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASS 307
Query: 325 SPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPP--PPAGGATAWGDL 382
+ P+ P+ T+ P S+ P G + +A AP+ P TA
Sbjct: 308 ASPM--------FKPIFTAPPKSEKEGPTP---PGPSVSATAPSSSSLPTTTSTTAPTFQ 356
Query: 383 LGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASA-STTTTVTAVTAEVDLFG 441
S+ +SVP A T PTTTA + T ASA S +T+ + D
Sbjct: 357 PVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTD--- 413
Query: 442 DAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF---APSEGSAEAAPEL-DLFA 497
PA G + ++ + A + + PF AP +A P + +F
Sbjct: 414 ------SASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQ 467
Query: 498 M-KPPETSVPVVTPTASTAPPVPATAPSPAPAVAA--AAAATTAATAAATTTTTTSAATA 554
KPP ++P T + + +P P+ + AA + +T AT+A T++ + +
Sbjct: 468 FGKPP--ALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFS 525
Query: 555 TTAPPALDI-FGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADL 613
T+ P +I FG +S + + P + P+ A PP A P S +
Sbjct: 526 NTSTPTFNIPFGSSAKS--PLPSYPGANPQPAFGA----AEGQPPGAAKPALTPSFGSSF 579
Query: 614 LSVDAFAAPSPATTASP---AKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLL 670
++ AAP+ A T +P K+ + V FG + AS+ A A
Sbjct: 580 TFGNS-AAPAAAPTPAPPSMIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQ 638
Query: 671 AGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSF-----DPSVFDGLGDLL 725
FGGS S T + F A T S SSSS F P F G
Sbjct: 639 PAFGGSTAVFSFGAATSS-------GFGATTQTASSGSSSSVFGSTTPSPFTFGG----- 686
Query: 726 MPTMAPAGQPAPVSMV--PPSPAMAASKALGSDLDSSLAS---LVGNLGIS--GTTTKKG 778
+ APAG + V P S A + + G+ S A+ G LG + GTT +
Sbjct: 687 --SAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFAGGLGQNALGTTGQST 744
Query: 779 DLQWNAG----EKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVG 834
+N G K + GG AT + G+ AP G TS GA S
Sbjct: 745 PFAFNVGSTTESKPVFGGT--------ATPTFGLNTPAPGVG----TSGSSLSFGASSA- 791
Query: 835 QPGAGF-GMPPAGTGMP 850
P GF G+ P G+ P
Sbjct: 792 -PAQGFVGVAPFGSAAP 807
Score = 77.0 bits (188), Expect = 7e-14
Identities = 133/543 (24%), Positives = 198/543 (36%), Gaps = 74/543 (13%)
Query: 369 PPPPAGGATAWGDLLGEDSLA-------ALSSVPSEAQISDPFAPEPTPPTTTAEIATAS 421
PPPP G + + L + A AL A S P T P+ T + A+
Sbjct: 106 PPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPITQPSFTFTLP-AA 164
Query: 422 ASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFA 481
A AS T++ A + L +P P E A A T + +
Sbjct: 165 APASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATT--------------EALS 210
Query: 482 PSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATA 541
P + + P L L PP + +P+ + PP PAP++ A T
Sbjct: 211 PPK-TPNLLPPLGLSQSGPPGL---LPSPSFDSNPPTTLLGLIPAPSMVPATDTKAPPTL 266
Query: 542 AATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQG- 600
A TTT A +A + P ++P AAP AA S F++PP+
Sbjct: 267 QAETTTKPQATSAPSPAPKQSFLFGTQNTSPSSPAAP---AASSASPMFKPIFTAPPKSE 323
Query: 601 ----ASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPA 656
P P S TA S + P+ +T +P + G AS P PA
Sbjct: 324 KEGPTPPGPSVSATAPSSS----SLPTTTSTTAP-------TFQPVFSSMGPPASVPLPA 372
Query: 657 ------SQAASSSSASADLLAGFGGSFMAPSP-SPVTPAQNNLLQPNFEAAFGTTPSTSS 709
+ A++ + +A L G + A +P + +P+ ++ +P F FG +SS
Sbjct: 373 PFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAF--GFGINSVSSS 430
Query: 710 SSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLG 769
S S S P + A Q + S +PAM + G + V
Sbjct: 431 SVSTTTSTATAAS---QPFLFGAPQASAASF---TPAMGSIFQFGKPPALPTTTTVTTFS 484
Query: 770 ISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVP--PV 827
S T +A + +G + APAT S P+ PT ++P
Sbjct: 485 QSLPTAVPTATSSSAAD--FSGFGSTLATSAPATSS---QPTLTFSNTSTPTFNIPFGSS 539
Query: 828 AGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSP--SPTPA 885
A +P PGA P G QP A+P + P FG++ G +P +PTPA
Sbjct: 540 AKSPLPSYPGAN-PQPAFGAA----EGQPPGAAKPALTPSFGSSFTFGNSAAPAAAPTPA 594
Query: 886 SQS 888
S
Sbjct: 595 PPS 597
Score = 40.8 bits (94), Expect = 0.006
Identities = 90/351 (25%), Positives = 120/351 (34%), Gaps = 68/351 (19%)
Query: 296 SGAPSPLSKSSPAT----TVTSPN-STPAKTID-----TSP--------PVDLFATASAA 337
SG S L+ S+PAT T+T N STP I SP P F A
Sbjct: 503 SGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQ 562
Query: 338 VPVSTSKPSSDLLDLQPDFSSG-----GAAAAAAPAPPPPAGGATAWGDLLGEDSLAALS 392
P +KP+ L P F S AA AAAP P P
Sbjct: 563 PP-GAAKPA-----LTPSFGSSFTFGNSAAPAAAPTPAP--------------------- 595
Query: 393 SVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAA-SPGEA 451
PS +I P P PT +A +T + A + FG + A S G A
Sbjct: 596 --PSMIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAA 653
Query: 452 PAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTP- 510
++ GA T T + + + G+ +P AAP + V TP
Sbjct: 654 TSSGFGA---TTQTASSGSSSSVFGSTTPSPFTFGGSAAP------AGSGSFGINVATPG 704
Query: 511 -TASTAPPVPATAPSPAPAVAAAAAATTAATAAATT-TTTTSAATATTAPPALDIFGDLF 568
+A+T S + A + A A TT +T A + + +FG
Sbjct: 705 SSATTGAFSFGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGG-- 762
Query: 569 ESTPEVAA-APKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDA 618
+TP P P S S A S+P QG V A S+ A
Sbjct: 763 TATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFVGVAPFGSAAPSFSIGA 813
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 90.9 bits (224), Expect = 5e-18
Identities = 158/626 (25%), Positives = 239/626 (38%), Gaps = 110/626 (17%)
Query: 299 PSPLS---KSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPD 355
P+P+S S+P+TT + + PP + T + V + P L + P
Sbjct: 1269 PTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQA-PRDGLTPVPP- 1326
Query: 356 FSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTA 415
APAP PP+ G A L+ P+ ++ P PT T A
Sbjct: 1327 ---------LAPAPRPPSSGLPA-----------VLNPRPT---LTPGRLPTPTLGTARA 1363
Query: 416 EIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACS 475
+ T + V + + EV A++PG AP ++P V ++L +
Sbjct: 1364 PMPTPTLVRPLLKLVHSPSPEVS------ASAPGAAPLTI------SSPLHVPSSLPGPA 1411
Query: 476 GNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAA 535
+ P S+ A + P +S+P+ PT P PA+AP P +A
Sbjct: 1412 SSP--MPIPNSSPLASPVSSTVSVPLSSSLPISVPTTL---PAPASAPLTIPI---SAPL 1463
Query: 536 TTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPD------AAPSIDLF 589
T +A+ A T+ T PP P V AAP P A+PS
Sbjct: 1464 TVSASGPALLTSVT--------PPL----------APVVPAAPGPPSLAPSGASPSASAL 1505
Query: 590 STDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPA----KVDSSGVIDLFGDA 645
+ ++P +S P L LL+ + P +T +PA V +S + F A
Sbjct: 1506 TLGLATAPSLSSSQTPGHPL---LLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSA 1562
Query: 646 FGSSASEPQPASQAASSSSASADLLAGFGG---SFMAPSPSP-------------VTPAQ 689
+ ++ + A+S+S A A LA + +APSP+P P
Sbjct: 1563 PNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVL 1622
Query: 690 NNLLQPNFEAAFGTTPSTS-SSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMA 748
+ P A +TP TS +S+S P+ L TM PA P+P+ PSPA
Sbjct: 1623 ASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPL----PSPAST 1678
Query: 749 ASKALGSDLDSSLASLVGNLGIS-GTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAG 807
+ AL L +L + +S GT +G LT ++ P A A
Sbjct: 1679 QTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQT--LSLTPASSLVPTPAQTLSLAP 1736
Query: 808 VPPSAPLQGAVPPTSSVPPVAGAPSVG-QPGAGFGMPPAGTGMPMMPQQPV--MFAQPMM 864
PP P Q + PP+A A VG P + PA + ++ V + P
Sbjct: 1737 GPPLGPTQ--TLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAP 1794
Query: 865 RPPFGAAAVPGTQLSPSPT--PASQS 888
P G AA L+P+ T PASQ+
Sbjct: 1795 VPTLGPAAAQTLALAPASTQSPASQA 1820
Score = 86.3 bits (212), Expect = 1e-16
Identities = 129/489 (26%), Positives = 190/489 (38%), Gaps = 68/489 (13%)
Query: 296 SGAPSPLSKSSP-ATTVTSPNSTP-AKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQ 353
+ +P P+ SSP A+ V+S S P + ++ S P L A ASA + + S P +
Sbjct: 1411 ASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLT------ 1464
Query: 354 PDFSSGGAAAAAAPAPP--PPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPP 411
S+ G A + PP P A G SLA + PS + ++ A P+
Sbjct: 1465 --VSASGPALLTSVTPPLAPVVPAAP------GPPSLAPSGASPSASALTLGLATAPSLS 1516
Query: 412 TTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAAL 471
++ A T++ V + + V A A SP PA++ + P+ P P A
Sbjct: 1517 SSQTP-GHPLLLAPTSSHVPGLNSTV-----APACSPVLVPASALASPFPSAPNPAPAQA 1570
Query: 472 DACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAA 531
AP+ SA A L M P+T++ +P AP +P APSP A
Sbjct: 1571 SL------LAPAS-SASQALATPLAPMAAPQTAILAPSPAPPLAP-LPVLAPSPGAAPVL 1622
Query: 532 AAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFST 591
A++ T A ++T TS A+A+ P + ST + AP P PS T
Sbjct: 1623 ASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAP--SSTQTMLPAPVPSPLPSPASTQT 1680
Query: 592 DAF----------SSPPQGAS--------PVPESSLTADLLSVDAFAAPSPATTASPAKV 633
A SSP Q S P P +L+ L+ + P+PA T S A
Sbjct: 1681 LALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLS---LTPASSLVPTPAQTLSLAPG 1737
Query: 634 DSSGVIDLFGDAFGSSASEPQPASQA------ASSSSASADLLAGFGGSFMAPSPSPVTP 687
G A + P A + +S+SA LLA + SP+PV P
Sbjct: 1738 PPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPV-P 1796
Query: 688 AQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDL--LMPTMAPAGQPAPVSMV---- 741
A +T S +S +S G L M + P + P ++
Sbjct: 1797 TLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSG 1856
Query: 742 PPSPAMAAS 750
PPSP A+
Sbjct: 1857 PPSPPSTAT 1865
Score = 78.6 bits (192), Expect = 2e-14
Identities = 162/691 (23%), Positives = 233/691 (33%), Gaps = 130/691 (18%)
Query: 264 IPDLTQAPSSLMETLEQHLNTLEGKK-------------PGNNEGSGAPSPLSKSSPATT 310
+P L SL + L L L G P S AP P S S
Sbjct: 1072 LPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPL 1131
Query: 311 VTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLL--DLQPDFSSG-----GAAA 363
P T T+ + AVP T P +L D+Q SG G A
Sbjct: 1132 TVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLA 1191
Query: 364 AAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASAS 423
+ A P AGG+ + + L AQ+ +P P S
Sbjct: 1192 SLAQRPVANAGGSKPLTFQIQGNKLTLTG-----AQVRQLAVGQPRPLQRNV---VHLVS 1243
Query: 424 ASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPAT-PTPVAAALDACSGNDP--- 479
A + + A V L A A +PG P + ++ P+T P P +L + P
Sbjct: 1244 AGGQHHLISQPAHVALI-QAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTM 1302
Query: 480 ------------FAPSEGSAEAAPELDLFAMKPPETSVP-VVTPTASTAP---PVP---- 519
AP +G P A +PP + +P V+ P + P P P
Sbjct: 1303 VNNTGVVKIVVRQAPRDGLTPVPPLAP--APRPPSSGLPAVLNPRPTLTPGRLPTPTLGT 1360
Query: 520 ATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPK 579
A AP P P + + + + + AA T + P + S P A++P
Sbjct: 1361 ARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPL-----HVPSSLPGPASSPM 1415
Query: 580 PDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVI 639
P + ++ +SP VP SS +SV P+PA+ + + +
Sbjct: 1416 P-------IPNSSPLASPVSSTVSVPLSSSLP--ISVPT-TLPAPASAPLTIPISAPLTV 1465
Query: 640 DLFGDAFGSSASEPQ---------PASQAASSSSASADLLAGFGGSFMAPS-PSPVTPAQ 689
G A +S + P P S A S +S SA L G APS S TP
Sbjct: 1466 SASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTL--GLATAPSLSSSQTPGH 1523
Query: 690 NNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPA-PVSMVP-PSPAM 747
LL P +SS P + + P + PA A P P P+PA
Sbjct: 1524 PLLLAP--------------TSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQ 1569
Query: 748 AASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAG 807
A+ A S +LA+ + + T +AP+
Sbjct: 1570 ASLLAPASSASQALATPLAPMAAPQTAI-----------------------LAPSP---- 1602
Query: 808 VPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPP 867
PP APL P + P +A + Q P + G + PV P++ P
Sbjct: 1603 APPLAPLPVLAPSPGAAPVLASS----QTPVPVMAPSSTPGTSLASASPVPAPTPVLAPS 1658
Query: 868 FGAAAVPGTQLSPSPTPAS-QSPKKPPAKDP 897
+P SP P+PAS Q+ PA P
Sbjct: 1659 STQTMLPAPVPSPLPSPASTQTLALAPALAP 1689
Score = 58.2 bits (139), Expect = 3e-08
Identities = 132/585 (22%), Positives = 201/585 (34%), Gaps = 123/585 (21%)
Query: 342 TSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQIS 401
TS+P + L L+P + A +PAPPP G SL +VP
Sbjct: 1096 TSRPPTPTLSLKP---TPPAPVRLSPAPPP------------GSSSLLKPLTVP------ 1134
Query: 402 DPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAP 461
P P TT TA+A+ + T + L D A P S G A
Sbjct: 1135 -PGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPS-GEVVSIGQLAS 1192
Query: 462 ATPTPVAAALDACSGNDPFA-PSEGS-----AEAAPELDLFAMKPPETSVP--------- 506
PVA A G+ P +G+ +L + +P + +V
Sbjct: 1193 LAQRPVANA----GGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQH 1248
Query: 507 -VVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPAL---- 561
+++ A A + A AP+P P + ++T +T A T + A A PP +
Sbjct: 1249 HLISQPAHVAL-IQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLA-ANQVPPTMVNNT 1306
Query: 562 DIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPV---PESSLTADLLSVDA 618
+ + P P P AP+ PP P P +LT L
Sbjct: 1307 GVVKIVVRQAPRDGLTPVPPLAPA---------PRPPSSGLPAVLNPRPTLTPGRL---- 1353
Query: 619 FAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFM 678
P+P + A + + ++ S + E ++ A+ + S+ L
Sbjct: 1354 ---PTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGP 1410
Query: 679 APSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPV 738
A SP P+ P + L P +T S SSS SV PT PA AP+
Sbjct: 1411 ASSPMPI-PNSSPLASP-----VSSTVSVPLSSSLPISV---------PTTLPAPASAPL 1455
Query: 739 SMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPK 798
++ P A A G L +S+ P
Sbjct: 1456 TI--PISAPLTVSASGPALLTSVT----------------------------------PP 1479
Query: 799 VAPATWSAGVPPSAPLQGAVPPTSSVP-PVAGAPSVGQ---PGAGFGMPPAGTGMPMMPQ 854
+AP +A PPS GA P S++ +A APS+ PG + P + +P +
Sbjct: 1480 LAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNS 1539
Query: 855 QPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDPLA 899
P++ P A+ + +P+P AS A LA
Sbjct: 1540 TVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALA 1584
Score = 48.5 bits (114), Expect = 3e-05
Identities = 126/517 (24%), Positives = 178/517 (34%), Gaps = 87/517 (16%)
Query: 448 PGEAPAASEGAAAPATPTPVAAAL------DACSGNDPFAPSEGSAEAAPELDLFAMKPP 501
P P E +A P TP PV L A P P+ S P L L ++P
Sbjct: 1023 PVRPPPGPELSAQP-TPGPVPQVLPASLMVSASPAGPPLIPA--SRPPGPVL-LPPLQPN 1078
Query: 502 ETSVPVV---------------TPTASTAPPVPAT---APSPAPAVAAAAAATTAAT--- 540
S+P V TPT S P PA +P+P P ++ T
Sbjct: 1079 SGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYT 1138
Query: 541 ---AAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSP 597
AAATTT+TT+A TTA PA +P++ A PS ++ S +S
Sbjct: 1139 FPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQA-----RLPSGEVVSIGQLASL 1193
Query: 598 PQ-------GASPVP------ESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGD 644
Q G+ P+ + +LT + A P P V + G L
Sbjct: 1194 AQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQ 1253
Query: 645 AFGSSASE-------PQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNF 697
+ + P P S SS+ ++ G A P +++
Sbjct: 1254 PAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVV 1313
Query: 698 EAA--FGTTPSTSSSSSFDPSVFDGLGDLL--MPTMAPAGQPAP------VSMVPPSPAM 747
A G TP + + P GL +L PT+ P P P M P+
Sbjct: 1314 RQAPRDGLTPVPPLAPAPRPP-SSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVR 1372
Query: 748 AASKALGSDLDSSLASLVG--NLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWS 805
K + S AS G L IS L A N P +P + +
Sbjct: 1373 PLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPI--PNSSPLASPVSST 1430
Query: 806 AGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGM------PMMPQQPVMF 859
VP S+ L +VP T +P A AP A + +G + P+ P P
Sbjct: 1431 VSVPLSSSLPISVPTT--LPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAP 1488
Query: 860 AQPMMRP----PFGAAAVPGTQLSPSPTPASQSPKKP 892
P + P P +A G +PS +SQ+P P
Sbjct: 1489 GPPSLAPSGASPSASALTLGLATAPS-LSSSQTPGHP 1524
Score = 46.6 bits (109), Expect = 1e-04
Identities = 119/521 (22%), Positives = 165/521 (31%), Gaps = 100/521 (19%)
Query: 298 APSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSK----PSSDLLDLQ 353
+P L +S A++ TS ++ PP DL A +PVS PS+ L L+
Sbjct: 2560 SPESLELASVASSETS-------SLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLE 2612
Query: 354 PDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALS---------SVPSEAQISDPF 404
G A P A G T GE+ +S S S+ + +P
Sbjct: 2613 AGSIPNGQEQEA----PDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPL 2668
Query: 405 -----------------APEPTPPTTTAEIATASASASTTTTVTA----------VTAEV 437
+PE TAE+A S S+S T++ +A+V
Sbjct: 2669 EADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADV 2728
Query: 438 DLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDAC-------SGNDPFAPSEGSAEAA 490
++ G PG+ P P V + P A+
Sbjct: 2729 EIRGQG-TGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSAS 2787
Query: 491 P-ELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTT 549
P + +M PE+S P+ P AP P P +A T +
Sbjct: 2788 PGSPSVRSMSGPESSPPIGGP-CEAAPSSSLPTPPQQPFIARRHIEL-GVTGGGSPENGD 2845
Query: 550 SAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVP--ES 607
A A T P G P+ +P DA +D + GA PVP E+
Sbjct: 2846 GALLAITPPAVKRRRG----RPPKKNRSPA-DAGRGVDEAPSSTLKGKTNGADPVPGPET 2900
Query: 608 SLTAD-LLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSAS 666
+ AD +L P P P V L P A + S
Sbjct: 2901 LIVADPVLEPQLIPGPQPL---GPQPVHRPN--PLLSPVEKRRRGRPPKARDLPIPGTIS 2955
Query: 667 ADLLAGFGGSFMA----PSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLG 722
+ AG G S P PSP+TP L+ P A T T S+S
Sbjct: 2956 S---AGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTS----------- 3001
Query: 723 DLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLAS 763
P G+P PPSP + L D S L S
Sbjct: 3002 ----PPKRKRGRP---PKNPPSPRPSQLPVLDRDSTSVLES 3035
Score = 45.4 bits (106), Expect = 2e-04
Identities = 108/529 (20%), Positives = 174/529 (32%), Gaps = 121/529 (22%)
Query: 445 AASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETS 504
A P PA++ A P PV+A P S + + + PP +
Sbjct: 2440 APRPRPTPASAPAAIPALVPVPVSA---------PVPISAPNPITILPVHILPSPPPPSQ 2490
Query: 505 VPVVTPTASTAPPV----PATAPSPA---------------PAVAAAAAATT-------- 537
+P + A T PP PA P PA P+V +A+ T
Sbjct: 2491 IPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPE 2550
Query: 538 ----------------AATAAATTTTTTSAATATTAPPALDIFG------DLFESTP--- 572
A+ A++ T++ + P A++I L S P
Sbjct: 2551 AELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLT 2610
Query: 573 -EVAAAPK------PDAAPSIDL-------------FSTDAFSSPPQGASPVP-ESSLTA 611
E + P PD+A L ++ PP AS P + L A
Sbjct: 2611 LEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEA 2670
Query: 612 DLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASE----PQPASQAASSSSASA 667
D S + A +P T+SP K ++ + SSA+ P PA +SA
Sbjct: 2671 DRTSEELTEAKTP--TSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADV 2728
Query: 668 DLLA-GFGGSFMAPSPSPVTPAQNNLLQ--PNFEAAFGTTPSTSSSSSFDPSVFDGLGDL 724
++ G G P P + L+ E ++S+ P V +
Sbjct: 2729 EIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSE----- 2783
Query: 725 LMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNA 784
T A G P+ SM P +S +G +++ +S + T ++ +
Sbjct: 2784 ---TSASPGSPSVRSMSGPE----SSPPIGGPCEAAPSSSL------PTPPQQPFIARRH 2830
Query: 785 GEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPP 844
E +TGG + P+ A PP+ + PP + P V + +
Sbjct: 2831 IELGVTGGGS--PENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGK 2888
Query: 845 AGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPP 893
P+ + ++ A P++ P QL P P P P P
Sbjct: 2889 TNGADPVPGPETLIVADPVLEP----------QLIPGPQPLGPQPVHRP 2927
Score = 34.3 bits (77), Expect = 0.54
Identities = 98/419 (23%), Positives = 143/419 (34%), Gaps = 59/419 (14%)
Query: 503 TSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALD 562
T+ P A P PA P P PA A AA A SA +AP +
Sbjct: 2423 TTTPPRCSPARERVPRPAPRPRPTPASAPAA-------IPALVPVPVSAPVPISAPNPIT 2475
Query: 563 IFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAP 622
I V P P I S+ A + PP P + A V
Sbjct: 2476 IL--------PVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLV---TPS 2524
Query: 623 SPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSAS-ADLLAGFGGSFMAPS 681
SP P+ S+ V +L G A AS S A + + S
Sbjct: 2525 SPLLLGPPSVPISASVTNL---PLGLRPEAELCAQALASPESLELASVASSETSSLSLVP 2581
Query: 682 PSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDG-------LGDLLMPTMAPAGQ 734
P + P +L P E TPS S + S+ +G + T+ P G+
Sbjct: 2582 PKDLLPVAVEIL-PVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGE 2640
Query: 735 PAPVSMVPPSPAMAASKALGSDLDSSLAS---LVGNLGISGTTTKKGDLQWNAGEKKLTG 791
P + S++ G +L S AS L L T+ + + + +
Sbjct: 2641 ELP---------LCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQ 2691
Query: 792 GANWQPKVAPATWSAGVPPSAPLQGAVPP---TSSVPPVAGAPSVGQPGAGFGMPPAGTG 848
AP+T S+ A PP TS+ + G G+P G PP
Sbjct: 2692 ELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRG-QGTGRP----GQPPGPKV 2746
Query: 849 MPMMPQQPVMFAQP-----MMRPPFGAAA--VPG-TQLSPSP-TPASQSPKKPPAKDPL 898
+ +P + V + R GAA+ VPG ++ S SP +P+ +S P + P+
Sbjct: 2747 LRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPI 2805
Score = 31.2 bits (69), Expect = 4.6
Identities = 28/125 (22%), Positives = 48/125 (38%), Gaps = 14/125 (11%)
Query: 514 TAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPE 573
T PP + +P P + AT A T T +T+ PP ++ P
Sbjct: 2966 TQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGRPP---------KNPP- 3015
Query: 574 VAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKV 633
+P+P P +D ST S G P+ ++ S D + P T + ++
Sbjct: 3016 ---SPRPSQLPVLDRDSTSVLESCGLGRRRQPQGQGESEGSSSDEDGS-RPLTRLARLRL 3071
Query: 634 DSSGV 638
++ G+
Sbjct: 3072 EAEGM 3076
>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
Length = 984
Score = 90.9 bits (224), Expect = 5e-18
Identities = 178/710 (25%), Positives = 251/710 (35%), Gaps = 152/710 (21%)
Query: 271 PSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDL 330
P+SL+ L LE K S P P S + T SP TP+ PP+ L
Sbjct: 321 PTSLLAPSTNPL--LESLKKMQTPPSLPPCPESAGAATTEALSPPKTPS----LLPPLGL 374
Query: 331 FATASAAV---PVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDS 387
+ + P SKP + LL L P S A AP P A AT +
Sbjct: 375 SQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAP-PTLQAETATK------PQA 427
Query: 388 LAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAAS 447
+A S P ++ + F + T P++ A A +SA +F F A
Sbjct: 428 TSAPSPAPKQSFL---FGTQNTSPSSPAAPAASSAP--------------PMFKPIFTAP 470
Query: 448 PGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPV 507
P + EG PTP ++ A + + P+ S A +F+ P SVP+
Sbjct: 471 P---KSEKEG------PTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPL 521
Query: 508 VTPTASTAPPVPATAP-SPAPAVAAAAAATTA------------------------ATAA 542
P PATAP + AP A+AT+A + ++
Sbjct: 522 PAPFFKQT-TTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSS 580
Query: 543 ATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAP------------KPDAAPSIDLFS 590
++ +TTTS ATA + P +FG P+ +AA KP A P+ +
Sbjct: 581 SSVSTTTSTATAASQP---FLFG-----APQASAASFTPAMGSIFQFGKPPALPTTTTVT 632
Query: 591 TDAFSSPPQGASPVPESSLTADLLSV-DAFAAPSPATTASPAKVDSSGVIDLFGDAFGSS 649
T FS A P SS AD A +PAT++ P S+ F FGSS
Sbjct: 633 T--FSQSLHTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSS 690
Query: 650 A---------SEPQPASQAASS---SSASADLLAGFGGSF---------MAPSPSP---- 684
A + PQPA AA +A L FG SF AP+P+P
Sbjct: 691 AKSPLPSYPGANPQPAFGAAEGQPPGAAKPALAPSFGSSFTFGNSAAPAAAPTPAPPSMI 750
Query: 685 -VTPAQ-NNLLQPNF-------------EAAFGTTPSTSSSSSFDPSVFDGLG-----DL 724
V PA + P F +AFG S+ + +VF G
Sbjct: 751 KVVPAYVPTPIHPIFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFFGAATSSGFGA 810
Query: 725 LMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNA 784
T + + PSP GS + S N+ G++T G + A
Sbjct: 811 TTQTASSGSSSSVFGSTTPSPFTFG----GSAAPAGSGSFGINVATPGSSTTTGAFSFGA 866
Query: 785 GEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAG---APSVG----QPG 837
G+ T + S P V T+ PV G P+ G PG
Sbjct: 867 GQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVSSTTESKPVFGGTATPTFGLNTPAPG 926
Query: 838 AGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQ 887
G G P Q + PFG+AA+ + + S TP ++
Sbjct: 927 VGTSGSSLSFGASSAPAQGFVGV-----APFGSAALSFSIGAGSKTPGAR 971
Score = 86.3 bits (212), Expect = 1e-16
Identities = 159/615 (25%), Positives = 227/615 (36%), Gaps = 79/615 (12%)
Query: 267 LTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSS--PATTVTSPNSTPAKTIDT 324
L APS + T + TL+ + + + APSP K S T TSP+S A +
Sbjct: 399 LIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASS 458
Query: 325 SPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPP--PPAGGATAWGDL 382
+PP+ P+ T+ P S+ P G + A AP+ P TA
Sbjct: 459 APPM--------FKPIFTAPPKSEKEGPTP---PGPSVTATAPSSSSLPTTTSTTAPTFQ 507
Query: 383 LGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASA-STTTTVTAVTAEVDLFG 441
S+ +SVP A T PTTTA + T ASA S +T+ + D
Sbjct: 508 PVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTD--- 564
Query: 442 DAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF---APSEGSAEAAPEL-DLFA 497
PA G + ++ + A + + PF AP +A P + +F
Sbjct: 565 ------SASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQ 618
Query: 498 M-KPP--ETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATA 554
KPP T+ V T + S VP TA S + A + +T A +A AT++ T +
Sbjct: 619 FGKPPALPTTTTVTTFSQSLHTAVP-TATSSSAADFSGFGSTLATSAPATSSQPTLTFSN 677
Query: 555 TTAPPALDIFGDLFES--------TPEVA---------AAPKPDAAPSIDLFSTDAFSSP 597
T+ P FG +S P+ A A KP APS T S+
Sbjct: 678 TSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALAPSFGSSFTFGNSAA 737
Query: 598 PQGA-SPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPA 656
P A +P P S ++ V P+P S+ + AFG+ AS QPA
Sbjct: 738 PAAAPTPAPPS-----MIKVVPAYVPTPIHPIFGGATHSAFGLKATASAFGAPASS-QPA 791
Query: 657 SQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPS 716
+++ A +GFG + S + + F FG + + + S SF +
Sbjct: 792 FGGSTAVFFGAATSSGFGATTQTASSGSSSSVFGSTTPSPF--TFGGSAAPAGSGSFGIN 849
Query: 717 V-FDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTT 775
V G AGQ + P ALG+ S+ + +S TT
Sbjct: 850 VATPGSSTTTGAFSFGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFA----FNVSSTTE 905
Query: 776 KKGDLQWNAGEKKLTGGANWQPKVAPATWSAGV-----PPSAPLQGAVPPTSSVPPVAGA 830
K G T G N AP ++G SAP QG V V P A
Sbjct: 906 SKPVF---GGTATPTFGLN---TPAPGVGTSGSSLSFGASSAPAQGFV----GVAPFGSA 955
Query: 831 PSVGQPGAGFGMPPA 845
GAG P A
Sbjct: 956 ALSFSIGAGSKTPGA 970
Score = 79.0 bits (193), Expect = 2e-14
Identities = 137/542 (25%), Positives = 201/542 (37%), Gaps = 72/542 (13%)
Query: 369 PPPPAGGATAWGDLLGEDSLA-------ALSSVPSEAQISDPFAPEPTPPTTTAEIATAS 421
PPPP G + + L + A AL A S P T P+ T + A+
Sbjct: 257 PPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPITQPSFTFTLP-AA 315
Query: 422 ASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFA 481
A AS T++ A + L +P P E A A T +A S P
Sbjct: 316 APASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATT--------EALS--PPKT 365
Query: 482 PSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATA 541
PS P L L PP + +P+ + PP PAP++ A T
Sbjct: 366 PS-----LLPPLGLSQSGPPGL---LPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTL 417
Query: 542 AATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPP--- 598
A T T A +A + P ++P AAP +AP + F++PP
Sbjct: 418 QAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSAPPM---FKPIFTAPPKSE 474
Query: 599 -QGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPA- 656
+G +P P S+TA S + + T + V SS G AS P PA
Sbjct: 475 KEGPTP-PGPSVTATAPSSSSLPTTTSTTAPTFQPVFSS---------MGPPASVPLPAP 524
Query: 657 -----SQAASSSSASADLLAGFGGSFMAPSP-SPVTPAQNNLLQPNFEAAFGTTPSTSSS 710
+ A++ + +A L G + A +P + +P+ ++ +P F FG +SSS
Sbjct: 525 FFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAF--GFGINSVSSSS 582
Query: 711 SSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGI 770
S S P + A Q + S +PAM + G + V
Sbjct: 583 VSTTTSTATAAS---QPFLFGAPQASAASF---TPAMGSIFQFGKPPALPTTTTVTTFSQ 636
Query: 771 SGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVP--PVA 828
S T +A + +G + APAT S P+ PT ++P A
Sbjct: 637 SLHTAVPTATSSSAAD--FSGFGSTLATSAPATSS---QPTLTFSNTSTPTFNIPFGSSA 691
Query: 829 GAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSP--SPTPAS 886
+P PGA P G QP A+P + P FG++ G +P +PTPA
Sbjct: 692 KSPLPSYPGAN-PQPAFGAA----EGQPPGAAKPALAPSFGSSFTFGNSAAPAAAPTPAP 746
Query: 887 QS 888
S
Sbjct: 747 PS 748
Score = 32.3 bits (72), Expect = 2.1
Identities = 68/297 (22%), Positives = 109/297 (36%), Gaps = 43/297 (14%)
Query: 607 SSLTADLLSVDAFAAPSPATTASPAKVDSS-GVIDLFGDAFGSSASEPQPASQAASSSSA 665
SS + L A PS + A + S+ G+ L+ SS+ PAS + +
Sbjct: 126 SSSMSSLTGAYASGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPER 185
Query: 666 SADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLL 725
A + + S +P+ + + E A TTP +S+ +
Sbjct: 186 PAKKIREEELCHHSSSSTPLAADRES----QGEKAADTTPRKKQNSNSQSTPGSSGQRKR 241
Query: 726 MPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQW--N 783
+ P+ + +++ PP P + S DLD KK LQW
Sbjct: 242 KVQLLPSRRGEQLTL-PPPPQLGYS-ITAEDLDLE---------------KKASLQWFNQ 284
Query: 784 AGEKKLTGGANWQPKVAPAT---WSAGVPPSAPLQGAVPPTSSVPPVAGA--PSVGQPGA 838
A E K +N + P T ++ +P +AP A PPTS + P S+ +
Sbjct: 285 ALEDKSDAASNSVTETPPITQPSFTFTLPAAAP---ASPPTSLLAPSTNPLLESLKKMQT 341
Query: 839 GFGMPP------AGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSP 889
+PP A T + P + P + PP G + L PSP+ S+ P
Sbjct: 342 PPSLPPCPESAGAATTEALSPPKT-----PSLLPPLGLSQSGPPGLLPSPSFDSKPP 393
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 90.5 bits (223), Expect = 6e-18
Identities = 137/579 (23%), Positives = 190/579 (32%), Gaps = 102/579 (17%)
Query: 366 APAPPPP----------AGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTA 415
+P PPPP A GA L +++P A + P P +
Sbjct: 32 SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRG 91
Query: 416 EIA-----TASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAA 470
E A T+ S+ + T L S E A + AP A A
Sbjct: 92 ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 151
Query: 471 LDACSGNDPFAPSEGSAE----AAPELDLFAMKP-----PETSVPVVTPTA----STAPP 517
SG P PS A A E+ L P P T P + ++ ST P
Sbjct: 152 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 211
Query: 518 VPATAPSPA-------PAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFES 570
PA P+ PA + +++ T ++ A + + A P+ L
Sbjct: 212 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 271
Query: 571 TPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASP 630
P P+ DAAP++ S+ ++P A P P + + L PS ATT+
Sbjct: 272 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLG 331
Query: 631 AKVDSSGVIDLFGDAFGSSASEPQ--------PASQAASSSSASADLLAGFGGSFMAPSP 682
+ + L A+ P P QA S AS L +P
Sbjct: 332 SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL---------SPLA 382
Query: 683 SPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLG-DLLMPTMAPAGQPAPVSMV 741
+P A N L +A F PS + F P + P+ AP AP V
Sbjct: 383 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 442
Query: 742 PPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAP 801
PPSP + + S T + P AP
Sbjct: 443 PPSPPASPP-----------------MSPSATPPPQAP----------------PPLAAP 469
Query: 802 ATWSAGVPPSAPLQGAVPPTSSVP-PVAGAPSVG--QPGAGFGMPPAGTGMPMMPQQPVM 858
A PP AP A PP ++P P A P P A M P T P P PV+
Sbjct: 470 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP--PVL 527
Query: 859 FAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDP 897
A + PP SP +P Q+P++PP P
Sbjct: 528 AAPLLQVPP-----------SPPASPTLQAPRRPPTPGP 555
Score = 86.7 bits (213), Expect = 9e-17
Identities = 157/655 (23%), Positives = 219/655 (33%), Gaps = 87/655 (13%)
Query: 284 TLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPP-------VDLFATASA 336
T + P + G AP P +SP P S+P + T+ P + + A +
Sbjct: 80 TRTSRPPASGRGERAP-PAKNTSPG-----PVSSPGRASGTTRPGPLGQKGLRISAEETV 133
Query: 337 AVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPS 396
A +T P L S+G + P P P+ G + +P
Sbjct: 134 ARGKATEAPKRSAL------SAGARRDTSGPTPGTPSPAMARRSRAAGTEV-----GLPR 182
Query: 397 EAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASE 456
A + P PPT + +SAS +TT + +A G AS
Sbjct: 183 PAP-----SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP------SAGGGLQRPASR 231
Query: 457 GAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPV--VTPTAST 514
++ ATP A + P AP+ S L A++PP+ + P P
Sbjct: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ--ALRPPQVTPPRKDAAPALGP 289
Query: 515 APPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTP-E 573
P PSP+ A + +A + T + T S AT + P L S P
Sbjct: 290 LSSSPLATPSPS-APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 348
Query: 574 VAAAPKPDAAPSIDLFSTDAFSSPPQG------ASPVPES--SLTADLLSVDAFAAPSPA 625
A P P A P++ L A SPP A+P P++ +L LL PSP
Sbjct: 349 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 408
Query: 626 TTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPV 685
A + S V + S P Q S AS + AP P
Sbjct: 409 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 468
Query: 686 TPAQNNLLQPNFEAAFGTTP---------STSSSSSFDPSVFDGLGDLLMPT-MAPAGQP 735
P Q P A T P S + F PS + L P AP
Sbjct: 469 PPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 528
Query: 736 APVSMVPPSPA-----MAASKALGSDLDSSLASLVGNLGIS-----------GTTTKKGD 779
AP+ VPPSP A + D+S++ L ++ +T D
Sbjct: 529 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD 588
Query: 780 LQWNAGEKKLTG----GANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQ 835
L ++ T G + P+ A A PP A L P S P G
Sbjct: 589 LAGHSSSATSTPEELRGYDSGPEGGAA---ASPPPDAELAACHPAAWSRGPAPPLAFRGA 645
Query: 836 PGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPK 890
PGA PPA TG ++ P A PG L P P+P + K
Sbjct: 646 PGAPLPWPPA-TGPGSADGLCTIYE---TEGPESATPAPGA-LDPGPSPGTSGGK 695
Score = 79.3 bits (194), Expect = 1e-14
Identities = 117/477 (24%), Positives = 179/477 (37%), Gaps = 87/477 (18%)
Query: 295 GSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSK------PSSD 348
G + SPL+ SP+ SP++ P+ SPP + A+ ++ T + PS
Sbjct: 288 GPLSSSPLATPSPSAP-PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP 346
Query: 349 LLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEP 408
L L A A P PP+ A+ L S A +++ + PF+P P
Sbjct: 347 LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL-LQAPFSPPP 405
Query: 409 TPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVA 468
+PP AS S + T P +AP + P+P A
Sbjct: 406 SPPVQAPFSPPASPPVSPSAT-----------------PPSQAPPSLAAPPLQVPPSPPA 448
Query: 469 AALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPA 528
+ + S P P AAP L L A PP+ + TP P PA+ P AP
Sbjct: 449 SPPMSPSATPP--PQAPPPLAAPPLQL-AKPPPQAPPALATPPLQALPSPPASFPGQAP- 504
Query: 529 VAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDL 588
+ +A+ + A APP L + P + P P A+P++
Sbjct: 505 ----------FSPSASLPMSPLATPPPQAPPVL--------AAPLLQVPPSPPASPTL-- 544
Query: 589 FSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGS 648
+P + +P P++S++ L++ P P + SP+ S DL G + S
Sbjct: 545 ------QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP--DLAGHS-SS 595
Query: 649 SASEPQ--------PASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAA 700
+ S P+ P AA+S A+L A ++ S P P F A
Sbjct: 596 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW---SRGPAPPLA-------FRGA 645
Query: 701 FGT----TPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVP-PSPAMAASKA 752
G P+T S+ DGL + + PAP ++ P PSP + KA
Sbjct: 646 PGAPLPWPPATGPGSA------DGLCTIYETEGPESATPAPGALDPGPSPGTSGGKA 696
Score = 71.6 bits (174), Expect = 3e-12
Identities = 111/469 (23%), Positives = 160/469 (34%), Gaps = 79/469 (16%)
Query: 445 AASPGEAPAASEGAAAPATPTPVAA--ALDACS--GNDPFAPSEGSA------EAAPELD 494
A +PG G+ P P AA L A G P A G E+AP
Sbjct: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG 78
Query: 495 LFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATA 554
P TS P + APP T+P P ++ A+
Sbjct: 79 -----PTRTSRPPASGRGERAPPAKNTSPGPV--------------------SSPGRASG 113
Query: 555 TTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAF--SSPPQGASPVPESSLTAD 612
TT P L G L S E A K AP S A +S P +P P + +
Sbjct: 114 TTRPGPLGQKG-LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 172
Query: 613 LLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAG 672
+ P PA +A P + + G A S +EP PA++ S+
Sbjct: 173 AAGTEV-GLPRPAPSARP-RPPTEGPRKSVSSASEHSTTEPSPAARRRPSA--------- 221
Query: 673 FGGSFMAPSPSPVTPAQNNLLQP--NFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMA 730
GG P+ ++ + L P + +A GT + + S P GL L P +
Sbjct: 222 -GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK---GLQALRPPQVT 277
Query: 731 PAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLT 790
P + A ++ P S + A+ + + S + L S T + G L
Sbjct: 278 PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLP-SPPATPPSQATTSLGSPTLQ 336
Query: 791 GGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMP 850
++ P S PL P PP P + P + PP
Sbjct: 337 ATHSFLP-------------SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT 383
Query: 851 MMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDPLA 899
PQ P A +++ PF SP P+P Q+P PPA P++
Sbjct: 384 PSPQAPNALAVHLLQAPF----------SPPPSPPVQAPFSPPASPPVS 422
Score = 53.9 bits (128), Expect = 7e-07
Identities = 70/276 (25%), Positives = 105/276 (38%), Gaps = 34/276 (12%)
Query: 299 PSPLSKSSPATTVTSPNSTPAKTID---TSPPVDLFATASAAVPVSTSKPSSDL------ 349
P + S PA+ SP++TP +PP+ L A P + P L
Sbjct: 439 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS 498
Query: 350 LDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLL-------GEDSLAALSSVPS---EAQ 399
Q FS + + A PPP LL +L A P+ +
Sbjct: 499 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 558
Query: 400 ISDP-----FAPEPTPPTTTAEIATASAS--ASTTTTVTAVTAEVDLF-----GDAFAAS 447
+S P AP P PP + + +T S A +++ T+ E+ + G A A+
Sbjct: 559 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP 618
Query: 448 PGEAP-AASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVP 506
P +A AA AA P P A A P+ P+ G A ++ + PE++ P
Sbjct: 619 PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 678
Query: 507 VVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAA 542
P A P P T+ A A A A A++ + A
Sbjct: 679 --APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQA 712
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 89.7 bits (221), Expect = 1e-17
Identities = 84/339 (24%), Positives = 118/339 (34%), Gaps = 39/339 (11%)
Query: 299 PSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSS 358
P + S P TT T TP T SPP+ ++ P T+ PS P ++
Sbjct: 1433 PPTTTPSPPITTTT----TPPPTTTPSPPI-----STTTTPPPTTTPSPPTTTPSPPTTT 1483
Query: 359 GGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIA 418
PPP + + ++ S + P P TTT
Sbjct: 1484 PSPPTTTTTTPPPTTTPS--------PPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPP 1535
Query: 419 TASASASTTTTVTAVTAEVDLFGDAFAASP---GEAPAASEGAAAPATPTPVAAALDACS 475
T + S TTT +T T+ L + P P + + P T TP + +
Sbjct: 1536 TTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTT 1595
Query: 476 GNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAA 535
PS + PP T+ P+ PT++T P P T PSP P
Sbjct: 1596 PPPTTTPSPPTTTTTTPPPTTTPSPP-TTTPITPPTSTTTLP-PTTTPSPPPTTTTTPPP 1653
Query: 536 TTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPE----VAAAPKPDAAPSIDLFST 591
TT + TTTT + T TT PP +TP P P PS + +T
Sbjct: 1654 TT-TPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTT 1712
Query: 592 DAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASP 630
++P +P P + PSP TT SP
Sbjct: 1713 ---TTPSSTTTPSPPPT---------TMTTPSPTTTPSP 1739
Score = 85.9 bits (211), Expect = 2e-16
Identities = 129/605 (21%), Positives = 192/605 (31%), Gaps = 98/605 (16%)
Query: 309 TTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPA 368
TT + P +TP SPP + + P +T P + P ++
Sbjct: 1397 TTPSPPTTTP------SPPP---TSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTT 1447
Query: 369 PPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTT 428
PPP S P + P P+PPTTT T + S TTT
Sbjct: 1448 PPP-----------------TTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTT 1490
Query: 429 TVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAE 488
T T P S P TP L + P P+ +
Sbjct: 1491 TTT----------------PPPTTTPSPPTTTPITPPASTTTLPPTTTPSP--PTTTTTT 1532
Query: 489 AAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTT 548
P P T+ P+ PT++T P P T PSP P TT + TTT +
Sbjct: 1533 PPPT----TTPSPPTTTPITPPTSTTTLP-PTTTPSPPPTTTTTPPPTTTPSPPTTTTPS 1587
Query: 549 TSAATATTAPPALDIF-GDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPES 607
T TT PP +TP P P I ++ P SP P +
Sbjct: 1588 PPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT 1647
Query: 608 SLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASA 667
+ T PSP TT +P+ ++ + P+S ++ S
Sbjct: 1648 TTTP-----PPTTTPSPPTTTTPSPPITTTT---------TPPPTTTPSSPITTTPSPPT 1693
Query: 668 DLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMP 727
+ + SP T ++ P+ TTPS +++ S P+ M
Sbjct: 1694 TTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPS-PPTT-------TMT 1745
Query: 728 TMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISG-TTTKKGDLQWNAGE 786
T+ P +P++ P P++ + V +G + K + G+
Sbjct: 1746 TLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGD 1805
Query: 787 KKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAG 846
+L G V W+A + A + VP V SVG P G
Sbjct: 1806 TELIG------DVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGG 1859
Query: 847 TGMPM-----------------MPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTP-ASQS 888
+PM P PP T ++P+PTP +Q+
Sbjct: 1860 V-IPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQT 1918
Query: 889 PKKPP 893
P P
Sbjct: 1919 PTTTP 1923
Score = 82.0 bits (201), Expect = 2e-15
Identities = 144/658 (21%), Positives = 215/658 (32%), Gaps = 136/658 (20%)
Query: 298 APSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFS 357
+P + S P TT T+P T + T+ P+ A+ + P +T P + P
Sbjct: 1478 SPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPP--- 1534
Query: 358 SGGAAAAAAPAPP------PPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPP 411
P+PP PP T ++ P S P P+PP
Sbjct: 1535 -----PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP 1589
Query: 412 --TTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAA 469
TTT T + S TTTT T P P +P T TP+
Sbjct: 1590 TITTTTPPPTTTPSPPTTTTTT--------------PPPTTTP-------SPPTTTPITP 1628
Query: 470 ALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVP------VVTPTASTAPPVP-ATA 522
+ PS PP T+ P TP +T P P T
Sbjct: 1629 PTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTT 1688
Query: 523 PSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDA 582
PSP + TT ++ TTTTT S+ T + PP +TP P P
Sbjct: 1689 PSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTT-------MTTPSPTTTPSPPT 1741
Query: 583 APSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASP-----AKVDS-- 635
L T +S P +P+P S+T S F+ +P T P +DS
Sbjct: 1742 TTMTTLPPTT--TSSPLTTTPLP-PSITPPTFS--PFSTTTPTTPCVPLCNWTGWLDSGK 1796
Query: 636 ------SGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQ 689
G +L GD G P A+ + ++ D+ G G + S +
Sbjct: 1797 PNFHKPGGDTELIGDVCG-----PGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICK 1851
Query: 690 NNLLQP----------NFE--------AAFGTTPSTSSSSSFDPSVFDGL--GDLLMPTM 729
N +P N+E TT +T+++ + P + + PT
Sbjct: 1852 NEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTP 1911
Query: 730 APAGQPAP-------VSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQW 782
P G P + V P+P ++ + ++ ++ +GT T
Sbjct: 1912 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT------- 1964
Query: 783 NAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGM 842
P P T + V P+ G PT++ P+ +V
Sbjct: 1965 --------------PTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPT---- 2004
Query: 843 PPAGTGMP-MMPQQPVMFAQPMMRP-----PFGAAAVPGTQLSPSPTP-ASQSPKKPP 893
P GT P P P P P T ++P+PTP +Q+P P
Sbjct: 2005 -PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2061
Score = 71.2 bits (173), Expect = 4e-12
Identities = 87/381 (22%), Positives = 120/381 (31%), Gaps = 51/381 (13%)
Query: 386 DSLAALSSVPSEAQISDPFAPEPTPPTTTAE-----------IATASASASTTTTVTAVT 434
D S P+ P + PPTTT T S +TTTT T
Sbjct: 1393 DKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTT 1452
Query: 435 AEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPS-EGSAEAAPEL 493
P P+ +P T TP + PS + P
Sbjct: 1453 TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPA 1512
Query: 494 DLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAAT 553
+ P T P PT +T P P T PSP P T+ T TTT + T
Sbjct: 1513 STTTLPPTTTPSP---PTTTTTTPPPTTTPSP-PTTTPITPPTSTTTLPPTTTPSPPPTT 1568
Query: 554 ATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADL 613
TT PP +TP +P PS +T ++PP +P P ++ T
Sbjct: 1569 TTTPPPT---------TTP----SPPTTTTPSPPTITT---TTPPPTTTPSPPTTTT--- 1609
Query: 614 LSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGF 673
P P TT SP ++ P P + + +
Sbjct: 1610 ------TTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPS----- 1658
Query: 674 GGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAG 733
+ PSP P+T + TTPS +++ PS + T P+
Sbjct: 1659 PPTTTTPSP-PITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSS 1717
Query: 734 ----QPAPVSMVPPSPAMAAS 750
P P +M PSP S
Sbjct: 1718 TTTPSPPPTTMTTPSPTTTPS 1738
Score = 66.2 bits (160), Expect = 1e-10
Identities = 103/532 (19%), Positives = 161/532 (30%), Gaps = 55/532 (10%)
Query: 305 SSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAA 364
++P TT T+ TP T +P T + P T + Q ++
Sbjct: 3807 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTTPITTTT 3860
Query: 365 AAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA---- 420
P P G T + + + P+ Q P TP TTT +
Sbjct: 3861 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPT 3915
Query: 421 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPA-----TPTPVAAALDACS 475
TTT +T T +P P + P T TP + +
Sbjct: 3916 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3975
Query: 476 GNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAA 535
P G+ T P T T +T P T +P P
Sbjct: 3976 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4035
Query: 536 TTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDA--APSIDLFSTDA 593
TT TT T T T T P I +T V P P P+ +T
Sbjct: 4036 TTTPITTTTTVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTT 4090
Query: 594 FSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEP 653
+P +P P + T + +P T + + ++ I ++ P
Sbjct: 4091 TVTP----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT------TTTVTP 4140
Query: 654 QPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSF 713
P + + + + + P+P+P T Q P T T + +
Sbjct: 4141 TPTPTGTQTPTTTPITTT----TTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQT 4195
Query: 714 DPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGT 773
P + AP + + P S S++ S L S +L+ L +
Sbjct: 4196 GPPTH--------TSTAPIAELTTSNPPPESSTPQTSRSTSSPLTES-TTLLSTLPPAIE 4246
Query: 774 TTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVP 825
T +GG P P+T ++ PP P +G +SS P
Sbjct: 4247 MTSTAPPSTPTAPTTTSGGHTLSP--PPSTTTS--PPGTPTRGTTTGSSSAP 4294
Score = 65.9 bits (159), Expect = 2e-10
Identities = 118/620 (19%), Positives = 187/620 (30%), Gaps = 85/620 (13%)
Query: 299 PSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSS 358
P+P + ++P TT T+ TP T +P T + P T + Q ++
Sbjct: 1893 PTPPT-TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTT 1945
Query: 359 GGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEI- 417
P P G T + + + P+ Q P TP TTT +
Sbjct: 1946 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVT 2000
Query: 418 ---ATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAP-----ATPTPVAA 469
TTT +T T +P P + P T TP
Sbjct: 2001 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2060
Query: 470 ALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAV 529
+ + P G+ T P T T +T P T +P P
Sbjct: 2061 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2120
Query: 530 AAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDA--APSID 587
TT TT T T T T P I +T V P P P+
Sbjct: 2121 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTT 2175
Query: 588 LFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFG 647
+T +P +P P + T + +P T + + ++ I
Sbjct: 2176 PITTTTTVTP----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT------ 2225
Query: 648 SSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPST 707
++ P P + + + + + P+P+P T Q P T T
Sbjct: 2226 TTTVTPTPTPTGTQTPTTTPITTT----TTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2280
Query: 708 SSSSSFDPSVFDGLGDLLMPTMAPAGQPAP-------VSMVPPSPAMAASKALGSDLDSS 760
+ + + + PT P G P + V P+P ++ + ++
Sbjct: 2281 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2340
Query: 761 LASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPP 820
++ +GT T P P T + V P+ G P
Sbjct: 2341 TTTVTPTPTPTGTQT---------------------PTTTPITTTTTVTPTPTPTGTQTP 2379
Query: 821 TSSVPPVAGAPSVGQPGAGFGMPPAGTGMP-MMPQQPVMFAQPMMRP-----PFGAAAVP 874
T++ P+ +V P GT P P P P P
Sbjct: 2380 TTT--PITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2432
Query: 875 GTQLSPSPTP-ASQSPKKPP 893
T ++P+PTP +Q+P P
Sbjct: 2433 TTTVTPTPTPTGTQTPTTTP 2452
Score = 65.5 bits (158), Expect = 2e-10
Identities = 116/614 (18%), Positives = 183/614 (29%), Gaps = 84/614 (13%)
Query: 305 SSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAA 364
++P TT T+ TP T +P T + P T + Q ++
Sbjct: 2013 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTTPITTTT 2066
Query: 365 AAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA---- 420
P P G T + + + P+ Q P TP TTT +
Sbjct: 2067 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPT 2121
Query: 421 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPA-----TPTPVAAALDACS 475
TTT +T T +P P + P T TP + +
Sbjct: 2122 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2181
Query: 476 GNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAA 535
P G+ T P T T +T P T +P P
Sbjct: 2182 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2241
Query: 536 TTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDA--APSIDLFSTDA 593
TT TT T T T T P I +T V P P P+ +T
Sbjct: 2242 TTTPITTTTTVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTT 2296
Query: 594 FSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEP 653
+P +P P + T + +P T + + ++ I ++ P
Sbjct: 2297 TVTP----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT------TTTVTP 2346
Query: 654 QPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSF 713
P + + + + + P+P+P T Q P T T + +
Sbjct: 2347 TPTPTGTQTPTTTPITTT----TTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQT 2401
Query: 714 DPSVFDGLGDLLMPTMAPAGQPAP-------VSMVPPSPAMAASKALGSDLDSSLASLVG 766
+ + PT P G P + V P+P ++ + ++ ++
Sbjct: 2402 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2461
Query: 767 NLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPP 826
+GT T P P T + V P+ G PT++ P
Sbjct: 2462 TPTPTGTQT---------------------PTTTPITTTTTVTPTPTPTGTQTPTTT--P 2498
Query: 827 VAGAPSVGQPGAGFGMPPAGTGMP-MMPQQPVMFAQPMMRP-----PFGAAAVPGTQLSP 880
+ +V P GT P P P P P T ++P
Sbjct: 2499 ITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2553
Query: 881 SPTP-ASQSPKKPP 893
+PTP +Q+P P
Sbjct: 2554 TPTPTGTQTPTTTP 2567
Score = 65.5 bits (158), Expect = 2e-10
Identities = 116/614 (18%), Positives = 183/614 (29%), Gaps = 84/614 (13%)
Query: 305 SSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAA 364
++P TT T+ TP T +P T + P T + Q ++
Sbjct: 2312 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTTPITTTT 2365
Query: 365 AAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA---- 420
P P G T + + + P+ Q P TP TTT +
Sbjct: 2366 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPT 2420
Query: 421 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPA-----TPTPVAAALDACS 475
TTT +T T +P P + P T TP + +
Sbjct: 2421 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2480
Query: 476 GNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAA 535
P G+ T P T T +T P T +P P
Sbjct: 2481 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2540
Query: 536 TTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDA--APSIDLFSTDA 593
TT TT T T T T P I +T V P P P+ +T
Sbjct: 2541 TTTPITTTTTVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTT 2595
Query: 594 FSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEP 653
+P +P P + T + +P T + + ++ I ++ P
Sbjct: 2596 TVTP----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT------TTTVTP 2645
Query: 654 QPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSF 713
P + + + + + P+P+P T Q P T T + +
Sbjct: 2646 TPTPTGTQTPTTTPITTT----TTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQT 2700
Query: 714 DPSVFDGLGDLLMPTMAPAGQPAP-------VSMVPPSPAMAASKALGSDLDSSLASLVG 766
+ + PT P G P + V P+P ++ + ++ ++
Sbjct: 2701 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2760
Query: 767 NLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPP 826
+GT T P P T + V P+ G PT++ P
Sbjct: 2761 TPTPTGTQT---------------------PTTTPITTTTTVTPTPTPTGTQTPTTT--P 2797
Query: 827 VAGAPSVGQPGAGFGMPPAGTGMP-MMPQQPVMFAQPMMRP-----PFGAAAVPGTQLSP 880
+ +V P GT P P P P P T ++P
Sbjct: 2798 ITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2852
Query: 881 SPTP-ASQSPKKPP 893
+PTP +Q+P P
Sbjct: 2853 TPTPTGTQTPTTTP 2866
Score = 65.5 bits (158), Expect = 2e-10
Identities = 116/614 (18%), Positives = 183/614 (29%), Gaps = 84/614 (13%)
Query: 305 SSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAA 364
++P TT T+ TP T +P T + P T + Q ++
Sbjct: 2611 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTTPITTTT 2664
Query: 365 AAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA---- 420
P P G T + + + P+ Q P TP TTT +
Sbjct: 2665 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPT 2719
Query: 421 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPA-----TPTPVAAALDACS 475
TTT +T T +P P + P T TP + +
Sbjct: 2720 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2779
Query: 476 GNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAA 535
P G+ T P T T +T P T +P P
Sbjct: 2780 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2839
Query: 536 TTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDA--APSIDLFSTDA 593
TT TT T T T T P I +T V P P P+ +T
Sbjct: 2840 TTTPITTTTTVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTT 2894
Query: 594 FSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEP 653
+P +P P + T + +P T + + ++ I ++ P
Sbjct: 2895 TVTP----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT------TTTVTP 2944
Query: 654 QPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSF 713
P + + + + + P+P+P T Q P T T + +
Sbjct: 2945 TPTPTGTQTPTTTPITTT----TTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQT 2999
Query: 714 DPSVFDGLGDLLMPTMAPAGQPAP-------VSMVPPSPAMAASKALGSDLDSSLASLVG 766
+ + PT P G P + V P+P ++ + ++ ++
Sbjct: 3000 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3059
Query: 767 NLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPP 826
+GT T P P T + V P+ G PT++ P
Sbjct: 3060 TPTPTGTQT---------------------PTTTPITTTTTVTPTPTPTGTQTPTTT--P 3096
Query: 827 VAGAPSVGQPGAGFGMPPAGTGMP-MMPQQPVMFAQPMMRP-----PFGAAAVPGTQLSP 880
+ +V P GT P P P P P T ++P
Sbjct: 3097 ITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3151
Query: 881 SPTP-ASQSPKKPP 893
+PTP +Q+P P
Sbjct: 3152 TPTPTGTQTPTTTP 3165
Score = 65.5 bits (158), Expect = 2e-10
Identities = 116/614 (18%), Positives = 183/614 (29%), Gaps = 84/614 (13%)
Query: 305 SSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAA 364
++P TT T+ TP T +P T + P T + Q ++
Sbjct: 2910 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTTPITTTT 2963
Query: 365 AAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA---- 420
P P G T + + + P+ Q P TP TTT +
Sbjct: 2964 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPT 3018
Query: 421 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPA-----TPTPVAAALDACS 475
TTT +T T +P P + P T TP + +
Sbjct: 3019 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3078
Query: 476 GNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAA 535
P G+ T P T T +T P T +P P
Sbjct: 3079 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3138
Query: 536 TTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDA--APSIDLFSTDA 593
TT TT T T T T P I +T V P P P+ +T
Sbjct: 3139 TTTPITTTTTVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTT 3193
Query: 594 FSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEP 653
+P +P P + T + +P T + + ++ I ++ P
Sbjct: 3194 TVTP----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT------TTTVTP 3243
Query: 654 QPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSF 713
P + + + + + P+P+P T Q P T T + +
Sbjct: 3244 TPTPTGTQTPTTTPITTT----TTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQT 3298
Query: 714 DPSVFDGLGDLLMPTMAPAGQPAP-------VSMVPPSPAMAASKALGSDLDSSLASLVG 766
+ + PT P G P + V P+P ++ + ++ ++
Sbjct: 3299 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3358
Query: 767 NLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPP 826
+GT T P P T + V P+ G PT++ P
Sbjct: 3359 TPTPTGTQT---------------------PTTTPITTTTTVTPTPTPTGTQTPTTT--P 3395
Query: 827 VAGAPSVGQPGAGFGMPPAGTGMP-MMPQQPVMFAQPMMRP-----PFGAAAVPGTQLSP 880
+ +V P GT P P P P P T ++P
Sbjct: 3396 ITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3450
Query: 881 SPTP-ASQSPKKPP 893
+PTP +Q+P P
Sbjct: 3451 TPTPTGTQTPTTTP 3464
Score = 65.5 bits (158), Expect = 2e-10
Identities = 116/614 (18%), Positives = 183/614 (29%), Gaps = 84/614 (13%)
Query: 305 SSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAA 364
++P TT T+ TP T +P T + P T + Q ++
Sbjct: 3209 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTTPITTTT 3262
Query: 365 AAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA---- 420
P P G T + + + P+ Q P TP TTT +
Sbjct: 3263 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPT 3317
Query: 421 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPA-----TPTPVAAALDACS 475
TTT +T T +P P + P T TP + +
Sbjct: 3318 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3377
Query: 476 GNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAA 535
P G+ T P T T +T P T +P P
Sbjct: 3378 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3437
Query: 536 TTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDA--APSIDLFSTDA 593
TT TT T T T T P I +T V P P P+ +T
Sbjct: 3438 TTTPITTTTTVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTT 3492
Query: 594 FSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEP 653
+P +P P + T + +P T + + ++ I ++ P
Sbjct: 3493 TVTP----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT------TTTVTP 3542
Query: 654 QPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSF 713
P + + + + + P+P+P T Q P T T + +
Sbjct: 3543 TPTPTGTQTPTTTPITTT----TTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQT 3597
Query: 714 DPSVFDGLGDLLMPTMAPAGQPAP-------VSMVPPSPAMAASKALGSDLDSSLASLVG 766
+ + PT P G P + V P+P ++ + ++ ++
Sbjct: 3598 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3657
Query: 767 NLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPP 826
+GT T P P T + V P+ G PT++ P
Sbjct: 3658 TPTPTGTQT---------------------PTTTPITTTTTVTPTPTPTGTQTPTTT--P 3694
Query: 827 VAGAPSVGQPGAGFGMPPAGTGMP-MMPQQPVMFAQPMMRP-----PFGAAAVPGTQLSP 880
+ +V P GT P P P P P T ++P
Sbjct: 3695 ITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3749
Query: 881 SPTP-ASQSPKKPP 893
+PTP +Q+P P
Sbjct: 3750 TPTPTGTQTPTTTP 3763
Score = 65.5 bits (158), Expect = 2e-10
Identities = 116/614 (18%), Positives = 183/614 (29%), Gaps = 84/614 (13%)
Query: 305 SSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAA 364
++P TT T+ TP T +P T + P T + Q ++
Sbjct: 3508 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTTPITTTT 3561
Query: 365 AAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA---- 420
P P G T + + + P+ Q P TP TTT +
Sbjct: 3562 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPT 3616
Query: 421 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPA-----TPTPVAAALDACS 475
TTT +T T +P P + P T TP + +
Sbjct: 3617 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3676
Query: 476 GNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAA 535
P G+ T P T T +T P T +P P
Sbjct: 3677 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3736
Query: 536 TTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDA--APSIDLFSTDA 593
TT TT T T T T P I +T V P P P+ +T
Sbjct: 3737 TTTPITTTTTVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTT 3791
Query: 594 FSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEP 653
+P +P P + T + +P T + + ++ I ++ P
Sbjct: 3792 TVTP----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT------TTTVTP 3841
Query: 654 QPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSF 713
P + + + + + P+P+P T Q P T T + +
Sbjct: 3842 TPTPTGTQTPTTTPITTT----TTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQT 3896
Query: 714 DPSVFDGLGDLLMPTMAPAGQPAP-------VSMVPPSPAMAASKALGSDLDSSLASLVG 766
+ + PT P G P + V P+P ++ + ++ ++
Sbjct: 3897 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3956
Query: 767 NLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPP 826
+GT T P P T + V P+ G PT++ P
Sbjct: 3957 TPTPTGTQT---------------------PTTTPITTTTTVTPTPTPTGTQTPTTT--P 3993
Query: 827 VAGAPSVGQPGAGFGMPPAGTGMP-MMPQQPVMFAQPMMRP-----PFGAAAVPGTQLSP 880
+ +V P GT P P P P P T ++P
Sbjct: 3994 ITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4048
Query: 881 SPTP-ASQSPKKPP 893
+PTP +Q+P P
Sbjct: 4049 TPTPTGTQTPTTTP 4062
Score = 63.5 bits (153), Expect = 8e-10
Identities = 86/389 (22%), Positives = 134/389 (34%), Gaps = 71/389 (18%)
Query: 305 SSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAA 364
++P TT T+ TP T +P T + P T + Q ++
Sbjct: 3991 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTTPITTTT 4044
Query: 365 AAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA---- 420
P P G T + + + P+ Q P TP TTT +
Sbjct: 4045 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPT 4099
Query: 421 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF 480
TTT +T T +P P + P TPTP +
Sbjct: 4100 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTT----- 4153
Query: 481 APSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPA---TAPSPAPAVAAAAAATT 537
P + P + P T+ P+ T T T P P T P + A A TT
Sbjct: 4154 -PITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTT 4211
Query: 538 AATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSP 597
+ ++T TS +T++ L EST ++ P P+I++ ST S+P
Sbjct: 4212 SNPPPESSTPQTSRSTSS----------PLTESTTLLSTLP-----PAIEMTSTAPPSTP 4256
Query: 598 PQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPAS 657
P ++ LS P P+TT SP + G S+S P P++
Sbjct: 4257 -----TAPTTTSGGHTLS------PPPSTTTSPPGTPTRGTTT-------GSSSAPTPST 4298
Query: 658 QAASSSSASADLLAGFGGSFMAPSPSPVT 686
+++SA P+P+P++
Sbjct: 4299 VQTTTTSA------------WTPTPTPLS 4315
Score = 62.0 bits (149), Expect = 2e-09
Identities = 134/691 (19%), Positives = 210/691 (30%), Gaps = 114/691 (16%)
Query: 265 PDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDT 324
P T PSS + T +T P + +P+ + S P TT+T+ T + T
Sbjct: 1699 PSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTT-TPSPPTTTMTTLPPTTTSSPLT 1757
Query: 325 SPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLG 384
+ P+ T P ST+ P++ + L + G + P P G GD+ G
Sbjct: 1758 TTPLPPSITPPTFSPFSTTTPTTPCVPL---CNWTGWLDSGKPNFHKPGGDTELIGDVCG 1814
Query: 385 EDSLAALS-------SVP-------------------SEAQISDPFAPEP---------- 408
A +S VP +E Q P
Sbjct: 1815 PGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQ 1874
Query: 409 -----TPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAP-- 461
T PTT T + + TTT +T T +P P + P
Sbjct: 1875 CCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1934
Query: 462 ---ATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPV 518
T TP + + P G+ T P T T +T P
Sbjct: 1935 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1994
Query: 519 PATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAP 578
T +P P TT TT T T T T P I +T V P
Sbjct: 1995 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-----TTTTTVTPTP 2049
Query: 579 KPDA--APSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSS 636
P P+ +T +P +P P + T + +P T + + ++
Sbjct: 2050 TPTGTQTPTTTPITTTTTVTP----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2105
Query: 637 GVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPN 696
I ++ P P + + + + + P+P+P T Q P
Sbjct: 2106 TPITT------TTTVTPTPTPTGTQTPTTTPITTT----TTVTPTPTP-TGTQTPTTTPI 2154
Query: 697 FEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAP-------VSMVPPSPAMAA 749
T T + + + + PT P G P + V P+P
Sbjct: 2155 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2214
Query: 750 SKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVP 809
++ + ++ ++ +GT T P P T + V
Sbjct: 2215 TQTPTTTPITTTTTVTPTPTPTGTQT---------------------PTTTPITTTTTVT 2253
Query: 810 PSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMP-MMPQQPVMFAQPMMRP-- 866
P+ G PT++ P+ +V P GT P P P P
Sbjct: 2254 PTPTPTGTQTPTTT--PITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTPTPTG 2306
Query: 867 ---PFGAAAVPGTQLSPSPTP-ASQSPKKPP 893
P T ++P+PTP +Q+P P
Sbjct: 2307 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2337
Score = 58.5 bits (140), Expect = 3e-08
Identities = 64/258 (24%), Positives = 94/258 (36%), Gaps = 39/258 (15%)
Query: 305 SSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAA 364
++P TT T+ TP T +P T + P T + P +S A
Sbjct: 4152 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTG---PPTHTSTAPIAE 4208
Query: 365 AAPAPPPPAGGATAWGDLLGE---DSLAALSSVPSEAQISDPFAPE-PTPPTTTAEIATA 420
+ PPP +S LS++P +++ P PT PTTT+ T
Sbjct: 4209 LTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTL 4268
Query: 421 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPV------------- 467
S STTT+ G + A +P + A P TPTP+
Sbjct: 4269 SPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTP-TPTPLSTPSIIRTTGLRP 4327
Query: 468 --AAALDACSGNDP-FAPSEG-------------SAEAAPELDLFAMKPPETSVPVVTPT 511
++ L C ND +AP E + + L+ + P T P TP+
Sbjct: 4328 YPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPS 4387
Query: 512 AST-APPVPATAPS-PAP 527
ST P P++ PS P P
Sbjct: 4388 KSTPTPSKPSSTPSKPTP 4405
Score = 57.0 bits (136), Expect = 8e-08
Identities = 83/399 (20%), Positives = 128/399 (32%), Gaps = 23/399 (5%)
Query: 507 VVTPTAST-APPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFG 565
+ TP+ T P P T+ + P + TT T TTT + T TT PP
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455
Query: 566 DLFE--STPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPS 623
+TP P P P+ SPP + P + T + P+
Sbjct: 1456 PPISTTTTPPPTTTPSP---PTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPA 1512
Query: 624 PATTASPAKVDSSGVIDLFGDAFGSSASEP--QPASQAASSSSASADLLAGFGGSFMAPS 681
TT P S ++ S P P + S+++ +
Sbjct: 1513 STTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP 1572
Query: 682 PSPVTPAQNNLLQPNFEAAFGTTP---STSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPV 738
P TP+ P+ TTP +T S + + PT P P
Sbjct: 1573 PPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTST 1632
Query: 739 SMVPPS-----PAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGA 793
+ +PP+ P + + S + + I+ TTT +T
Sbjct: 1633 TTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPP---PTTTPSSPITTTP 1689
Query: 794 NWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMP 853
+ P T S PS+P+ P+S+ P ++ P P T M +P
Sbjct: 1690 S-PPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLP 1748
Query: 854 QQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKP 892
P + P+ P + P T SP T +P P
Sbjct: 1749 --PTTTSSPLTTTPLPPSITPPT-FSPFSTTTPTTPCVP 1784
Score = 46.6 bits (109), Expect = 1e-04
Identities = 131/670 (19%), Positives = 205/670 (30%), Gaps = 124/670 (18%)
Query: 265 PDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSP---NSTPAKT 321
P T PS + T T P S + ++ SP TT +SP +TP+ T
Sbjct: 1659 PPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSST 1718
Query: 322 IDTSPPVDLFATASAAVPVST-SKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWG 380
SPP T S P +T S P++ + L P +S
Sbjct: 1719 TTPSPPPTTMTTPS---PTTTPSPPTTTMTTLPPTTTS---------------------- 1753
Query: 381 DLLGEDSLAALSSVPSEAQISDP-FAPEPTPPTTTAEIATASASA---STTTTVTAVTAE 436
+ L++ P I+ P F+P T TT + + + S +
Sbjct: 1754 --------SPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGD 1805
Query: 437 VDLFGDAFAASPGEAPAAS-EGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDL 495
+L GD PG A S P P C + + + +
Sbjct: 1806 TELIGD--VCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPM 1863
Query: 496 FAMKPPETSVP----VVTPTASTA-----PPVPATAP-------SPAPAVAAAAAATTAA 539
E +V V PT T P P T P +P P TT
Sbjct: 1864 AFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTP 1923
Query: 540 TAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDA--APSIDLFSTDAFSSP 597
TT T T T T P I +T V P P P+ +T +P
Sbjct: 1924 ITTTTTVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1978
Query: 598 PQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPAS 657
+P P + T + +P T + + ++ I ++ P P
Sbjct: 1979 ----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT------TTTVTPTPTP 2028
Query: 658 QAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSV 717
+ + + + + P+P+P T Q P T T + + +
Sbjct: 2029 TGTQTPTTTPITTT----TTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2083
Query: 718 FDGLGDLLMPTMAPAGQPAP-------VSMVPPSPAMAASKALGSDLDSSLASLVGNLGI 770
+ PT P G P + V P+P ++ + ++ ++
Sbjct: 2084 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2143
Query: 771 SGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGA 830
+GT T P P T + V P+ G PT++ P+
Sbjct: 2144 TGTQT---------------------PTTTPITTTTTVTPTPTPTGTQTPTTT--PITTT 2180
Query: 831 PSVGQPGAGFGMPPAGTGMP-MMPQQPVMFAQPMMRP-----PFGAAAVPGTQLSPSPTP 884
+V P GT P P P P P T ++P+PTP
Sbjct: 2181 TTVTPTPT-----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2235
Query: 885 -ASQSPKKPP 893
+Q+P P
Sbjct: 2236 TGTQTPTTTP 2245
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 83.6 bits (205), Expect = 8e-16
Identities = 113/426 (26%), Positives = 161/426 (37%), Gaps = 91/426 (21%)
Query: 253 VAEQVGIDKGDIPDLT--QAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATT 310
+ E+ G +G + T AP +T ++T E +P + + P+P +SPA
Sbjct: 964 ITEEDGTPEGPVTPATTVHAPEE-PDTAAVRVSTPE--EPAS-PAAAVPTPEEPTSPAAA 1019
Query: 311 VTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPP 370
V +P TSP +AAVP +P+S AAA P P
Sbjct: 1020 VPTPEE------PTSP--------AAAVP-PPEEPTS--------------PAAAVPTPE 1050
Query: 371 PPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTV 430
P A A VP+ + + P A PTP T+ A T+
Sbjct: 1051 EPTSPAAA---------------VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1095
Query: 431 TAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAA 490
AV + A A E PA + A A PTP +P +P A A
Sbjct: 1096 AAVPTPEEPTSPAAAVPTPEEPA----SPAAAVPTP----------EEPASP----AAAV 1137
Query: 491 PELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTS 550
P + A P P + +A+ A P P + SPA AV A + + A AT TS
Sbjct: 1138 PTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTS 1197
Query: 551 AATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPV------ 604
A + P A+ L E T A+ P + S+ A S+P + SP
Sbjct: 1198 PAASVPTPAAM--VATLEEFTSPAASVPTSEEPASL----AAAVSNPEEPTSPAAAVPTL 1251
Query: 605 --PESS----LTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQ 658
P SS LT + LS A + P+P ASPA S+ + +A+ P P
Sbjct: 1252 EEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSN-----LEEPASPAAAVPTPEVA 1306
Query: 659 AASSSS 664
A ++S
Sbjct: 1307 AIPAAS 1312
Score = 81.6 bits (200), Expect = 3e-15
Identities = 128/495 (25%), Positives = 180/495 (36%), Gaps = 98/495 (19%)
Query: 300 SPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSG 359
+P +PATTV +P + S P + A+ +AAVP + +P+S
Sbjct: 970 TPEGPVTPATTVHAPEEPDTAAVRVSTPEEP-ASPAAAVP-TPEEPTSP----------- 1016
Query: 360 GAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIAT 419
AAA P P P A A VP + + P A PTP T+ A
Sbjct: 1017 ---AAAVPTPEEPTSPAAA---------------VPPPEEPTSPAAAVPTPEEPTSPAAA 1058
Query: 420 ASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDP 479
T+ AV + A A E P S AA P P + A + +P
Sbjct: 1059 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT-SPAAAVPTPEEPTSPAAAVPTPEEP 1117
Query: 480 FAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAA 539
+P A A P P E + P + A P P PAPAV + +AA
Sbjct: 1118 ASP----AAAVPT-------PEEPASP------AAAVPTPEEPAFPAPAVPTPEESASAA 1160
Query: 540 TAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQ 599
A T + S A A P F + + E + P+ + + + F+SP
Sbjct: 1161 VAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSP-- 1218
Query: 600 GASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQA 659
A+ VP S A L A A +P SPA A + EP
Sbjct: 1219 -AASVPTSEEPASL----AAAVSNPEEPTSPA-------------AAVPTLEEP------ 1254
Query: 660 ASSSSASADLLAGFGGSFMAPSPSPVTPAQ-----NNLLQPNFEAAFGTTPSTSS--SSS 712
+SSA+A L S A P+P PA +NL +P AA TP ++ ++S
Sbjct: 1255 --TSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAAS 1312
Query: 713 FDPSVFDGLGDLLMPTM---APAGQP-----APVSMVPPS----PAMAASKALGSDLDSS 760
+ +P M +P G P A VP S P + + + G +
Sbjct: 1313 VPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASSTGMWIKED 1372
Query: 761 LASLVGNLGISGTTT 775
L SLV GI T+
Sbjct: 1373 LDSLV--FGIKEVTS 1385
Score = 75.9 bits (185), Expect = 2e-13
Identities = 118/517 (22%), Positives = 175/517 (33%), Gaps = 51/517 (9%)
Query: 392 SSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVT------AVTAEVDLFGDAFA 445
++VP+ D P P T+ A + +A V V + V L +
Sbjct: 838 AAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVT 897
Query: 446 ASPGEAPAASEGAAAPATPTPV---AAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPE 502
A+ AP E A PA V AA+ A S + AP+ +A + A PE
Sbjct: 898 AAAVSAP---ERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPE 954
Query: 503 TSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAP---- 558
+ +T + P +PA V A TAA +T S A A P
Sbjct: 955 WAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPT 1014
Query: 559 -PALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVD 617
PA + ++P A P + T + P A P PE +
Sbjct: 1015 SPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS------P 1068
Query: 618 AFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSF 677
A A P+P SPA + A + EP + A + A A
Sbjct: 1069 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPE 1128
Query: 678 MAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAP 737
SP+ P +P F A TP S+S++ + +PT + PA
Sbjct: 1129 EPASPAAAVPTPE---EPAFPAPAVPTPEESASAA-----------VAVPTPEESASPAA 1174
Query: 738 VSMVP-PSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQ 796
P S + AA A + S AS+ + T E+ + A+
Sbjct: 1175 AVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATL-----------EEFTSPAASVP 1223
Query: 797 PKVAPATWSAGVP-PSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQ 855
PA+ +A V P P A + P + A +V P P A P P
Sbjct: 1224 TSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTP-EELSSPAASVPTPEEPAS 1282
Query: 856 PVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKP 892
P + P AAAVP +++ P + +P+ P
Sbjct: 1283 PAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVP 1319
Score = 45.8 bits (107), Expect = 2e-04
Identities = 76/336 (22%), Positives = 116/336 (34%), Gaps = 49/336 (14%)
Query: 575 AAAPKPDAAPSIDLFSTDAFSSPPQGASPVP-ESSLTADLLSVD-------AFAAPSPAT 626
AA P P+ SI ++ P P E L A ++S++ A +AP AT
Sbjct: 849 AALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERAT 908
Query: 627 TASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPS-PV 685
+ G + A SS E PA AA + + +AGF + A + + P+
Sbjct: 909 VPAVTVSVPEGTAAV---AAVSSPEETAPAVAAAITQEGMS-AVAGFSPEWAALAITVPI 964
Query: 686 TPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSP 745
T P TP+T+ + +P + + T PA P P
Sbjct: 965 TEEDGTPEGP-------VTPATTVHAPEEPDT----AAVRVSTPEEPASPAAAVPTPEEP 1013
Query: 746 AMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWS 805
A+ + +S A+ V E+ + A P + +
Sbjct: 1014 TSPAAAVPTPEEPTSPAAAVP-----------------PPEEPTSPAAAVPTPEEPTSPA 1056
Query: 806 AGVP----PSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQ 861
A VP P++P P P A P+ +P + P A P P P
Sbjct: 1057 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS----PAAAVPTPEEPTSPAAAVP 1112
Query: 862 PMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDP 897
P AAAVP + SP A +P++P P
Sbjct: 1113 TPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAP 1148
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 83.2 bits (204), Expect = 1e-15
Identities = 140/618 (22%), Positives = 212/618 (34%), Gaps = 67/618 (10%)
Query: 299 PSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVST--SKPSSDLLDLQPDF 356
PS + SS AT ++P +T T T+ T S A+P ST + P +L
Sbjct: 2975 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATT 3034
Query: 357 SSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPE-PTPPTTTA 415
+ ++ A + + P A + + + + +PS + PE T P T
Sbjct: 3035 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATM 3094
Query: 416 EIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACS 475
S++ TT T T +T + A S P+++ G T AA A +
Sbjct: 3095 STIHPSSTPETTHTSTVLTTKAT---TTRATSSMSTPSSTPGTTWILTELTTAATTTAAT 3151
Query: 476 GNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAA 535
G P A + + + P T+ V PT STA A + A A
Sbjct: 3152 G--PTATPSSTPGTT-----WILTEPSTTATVTVPTGSTA---------TASSTRATAGT 3195
Query: 536 TTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFS 595
T+ ATT T S+ ++ P ST A A PS L + A++
Sbjct: 3196 LKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGT--AWT 3253
Query: 596 SPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQP 655
Q +P S A PS ++P V +S V+ ++ S P
Sbjct: 3254 RLSQTTTPTATMST----------ATPS----STPETVHTSTVLTTTTTTTRATGSVATP 3299
Query: 656 ASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDP 715
+S ++ + G + PS SP T L P + TTP T+ S+ P
Sbjct: 3300 SSTPGTAHTTKVPTTTTTGFT-ATPSSSPGT-----ALTPPVWISTTTTP-TTRGSTVTP 3352
Query: 716 SVFDG---LGDLLMPT--------MAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASL 764
S G +L T MA S PPS A+ + ++ +S
Sbjct: 3353 SSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSST 3412
Query: 765 VGNLGI----SGTTTKKGDLQWNAGEKKLTGGANWQ--PKVAPATWSAGVPPSAPLQGAV 818
G I + T T G + P T +PPS+P
Sbjct: 3413 PGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRT 3472
Query: 819 PPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFA-QPMMR----PPFGAAAV 873
TS+ + G + +P PA T P + + P R PP
Sbjct: 3473 AWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTT 3532
Query: 874 PGTQLSPSPTPASQSPKK 891
PG S T A+ +P K
Sbjct: 3533 PGHTRGTSRTTATATPSK 3550
Score = 81.3 bits (199), Expect = 4e-15
Identities = 122/519 (23%), Positives = 200/519 (38%), Gaps = 46/519 (8%)
Query: 265 PDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVT-----SPNSTPA 319
P T + L T +T P + G+ AP P +SPATT T + +S+
Sbjct: 4247 PGTTWILTELTTTATTTASTGSTATPSSTPGT-APPPKVLTSPATTPTATSSKATSSSSP 4305
Query: 320 KTIDTSPPVDLFATASAAVPVSTSKPSSDL--LDLQPDFSSGGAAAAAAPAP---PPPAG 374
+T T P + AT S A V T PSS L P+ ++ A + P P
Sbjct: 4306 RTATTLPVLTSTATKSTATSV-TPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTH 4364
Query: 375 GATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVT 434
+T + +S PS + E T TT +A+ S+T T +
Sbjct: 4365 TSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWIL 4424
Query: 435 AEVDLFGDAFAASPGEA-PAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPEL 493
E+ A++ A P+++ G T A + +G+ A S + P +
Sbjct: 4425 TELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHV 4484
Query: 494 DLFAMKPPETS---VPVVTP-TASTAPPVPATAPSP-APAVAAAAAATTAATAAATTTTT 548
A P TS P +P TA+ P + +TA +P A + A +++ T + TT
Sbjct: 4485 STTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTT 4544
Query: 549 TSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESS 608
T AT +TA P+ STPE A + +T + ++P S P ++
Sbjct: 4545 TPTATMSTATPS---------STPETVHTSTVLTATATTTGATGSVATP----SSTPGTA 4591
Query: 609 LTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASAD 668
T + P+ TT A SS L + S+ + P + S S+ +
Sbjct: 4592 HTTKV--------PTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPS 4643
Query: 669 LLAGFGGSFMAPSPSPVTPAQNNLLQPNFEA-AFGTTPSTSSSSSFDPSVFDGLGDLLMP 727
+ G + + + T A ++ P+ GT PS ++++ + G P
Sbjct: 4644 SIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTA----TTITATGSTTNP 4699
Query: 728 TMAPAGQP-APV-SMVPPSPAMAASKALGSDLDSSLASL 764
+ P P PV + +PA +SKA S + +L
Sbjct: 4700 SSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTL 4738
Score = 80.9 bits (198), Expect = 5e-15
Identities = 127/561 (22%), Positives = 195/561 (34%), Gaps = 71/561 (12%)
Query: 302 LSKSSPATTVTSPNSTPAKTIDTSPPVDLF----ATASAAVPVSTSKPSSDLLDLQPDFS 357
L+ ++ T T +TP+ T T+PP + T +A +TS S P +
Sbjct: 4256 LTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLT 4315
Query: 358 SGGAAAAAAPAPPPPAGGATAWGDL-------LGEDSLAALSSVPSEAQISDPFAPEPTP 410
S + A P P+ G L + S SS P S + T
Sbjct: 4316 STATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATT 4375
Query: 411 PTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAA 470
T+ +T S++ TT +T +T A P P+++ G T A
Sbjct: 4376 TRATSSTSTPSSTPGTTWILTELTTAAT---TTAATGPTATPSSTPGTTWILTELTTTAT 4432
Query: 471 LDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVA 530
A +G S + + P + + P T+ V PT STA A + P V+
Sbjct: 4433 TTASTG------STATPSSTPG-TTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVS 4485
Query: 531 AAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFS 590
A T ++ AT +++ ATA PAL ST A A PS L +
Sbjct: 4486 TTATTPTVTSSKATPSSSPGTATAL---PAL-------RSTATTPTATSFTAIPSSSLGT 4535
Query: 591 TDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSA 650
T ++ Q +P S A PS ++P V +S V+ G++
Sbjct: 4536 T--WTRLSQTTTPTATMST----------ATPS----STPETVHTSTVLTATATTTGATG 4579
Query: 651 SEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPS---- 706
S P+S ++ + G + PS SP T L P + TTP+
Sbjct: 4580 SVATPSSTPGTAHTTKVPTTTTTGFT-ATPSSSPGT-----ALTPPVWISTTTTPTTTTP 4633
Query: 707 TSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVG 766
T+S S+ PS G A SM PS S S SL +
Sbjct: 4634 TTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPS-----SSTQTSGTPPSLTTTAT 4688
Query: 767 NLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPP 826
+ +G+TT G +T P + + S + P T++ P
Sbjct: 4689 TITATGSTTNPSS---TPGTTPIT------PVLTSTATTPAATSSKATSSSSPRTATTLP 4739
Query: 827 VAGAPSVGQPGAGFGMPPAGT 847
V + + F P+ T
Sbjct: 4740 VLTSTATKSTATSFTPIPSST 4760
Score = 75.9 bits (185), Expect = 2e-13
Identities = 109/459 (23%), Positives = 162/459 (35%), Gaps = 59/459 (12%)
Query: 296 SGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVST--SKPSSDLLDLQ 353
S PS + SS AT ++P +T T T+ +T S A P ST + P +L
Sbjct: 1886 SHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTT 1945
Query: 354 PDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEA-QISDPFAPEPTPPT 412
+ ++ A + P A A + +++ +PS + + + T PT
Sbjct: 1946 ATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPT 2005
Query: 413 TTAEIATASASASTTTTVTAVTAEVDLFG-DAFAASPGEAPAASEGAAAPATPTPVAAAL 471
T AT S++ T T T +TA G A+P P + P T T A
Sbjct: 2006 ATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTAT 2065
Query: 472 DACSGNDPFAPSEG-SAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVA 530
+ S P S P + P +S+P T TA+ T + + A
Sbjct: 2066 PSSSPGTALTPPVWISTTTTPTTRGSTVTP--SSIPGTTHTATVLTTTTTTVATGSMATP 2123
Query: 531 AAAAATTAATAAATTTTTTSAATATT----APPALDIFGDLFESTPEVAAAPKPDAAPSI 586
+++ T+ + TTT TT AT +T + P + +T AA PS
Sbjct: 2124 SSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSS 2183
Query: 587 DLFSTDAFSSP-----PQGASPVPES---------SLTADLLSVDAFAAPSPATTASPAK 632
L +T P G S P S S T+ +L PS T+ + A
Sbjct: 2184 ALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAA 2243
Query: 633 VDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNL 692
++G A S P P+S+ S PSP TP
Sbjct: 2244 --TTGTTQHSTPAL----SSPHPSSRTTES----------------PPSPGTTTPGHTTA 2281
Query: 693 LQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAP 731
A TPS + +S+ PS PT AP
Sbjct: 2282 TSRTTATA---TPSKTRTSTLLPS---------SPTSAP 2308
Score = 71.2 bits (173), Expect = 4e-12
Identities = 108/465 (23%), Positives = 162/465 (34%), Gaps = 72/465 (15%)
Query: 299 PSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVST-------SKPSSDLLD 351
PS + SS AT ++P +T T T+ +T S A P ST ++PS+
Sbjct: 3675 PSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 3734
Query: 352 LQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPP 411
P S+ A++ A A P TA + SS P A T P
Sbjct: 3735 TVPTGSTATASSTQATAGTPHVS-TTATTPTVTSSKATPFSS-PGTATALPALRSTATTP 3792
Query: 412 TTTAEIATASASA---------STTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPA 462
T T+ A S+S +TT T T TA + S A+ A +
Sbjct: 3793 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGS 3852
Query: 463 TPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATA 522
TP + A + P + G A PP TPT S + P++
Sbjct: 3853 VATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSV 3912
Query: 523 PSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDA 582
P T T TTTTT+ AT + A P+ S+ + + P
Sbjct: 3913 PG------------TTHTPTVLTTTTTTVATGSMATPS---------SSTQTSGTPPSLI 3951
Query: 583 APSIDLFSTDAFSSPPQ--GASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVID 640
+ + +T + ++P G +P+P T A +PA T+S S
Sbjct: 3952 TTATTITATGSTTNPSSTPGTTPIPPVLTT---------TATTPAATSSTVTPSS----- 3997
Query: 641 LFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAA 700
A G++ + P P + A + G S SP V A +
Sbjct: 3998 ----ALGTTHTPPVPNTTATT-----------HGRSLSPSSPHTVRTAWTSATSGTLGTT 4042
Query: 701 FGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSP 745
T PST +S + P+ G P ++ + + PPSP
Sbjct: 4043 HITEPSTGTSHT--PAATTGTTQHSTPALSSPHPSSRTTESPPSP 4085
Score = 70.1 bits (170), Expect = 9e-12
Identities = 100/444 (22%), Positives = 155/444 (34%), Gaps = 56/444 (12%)
Query: 268 TQAPSSLMET---LEQHLNTLEGKKPGNNEGSGAPSPLSKSSP--ATTVTSPNSTPAKTI 322
T PSS T L + T P + + + + + +P +TT T+P T +K
Sbjct: 2455 TATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT 2514
Query: 323 DTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDL 382
S P ATA A+ + + P++ P S G + P A +TA
Sbjct: 2515 PFSSPGT--ATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTA---- 2568
Query: 383 LGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGD 442
SS P S T T +AT S++ T T +T F
Sbjct: 2569 -------TPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTA 2621
Query: 443 AFAASPGEAPAASEGAAAPATPTPVAAALDACS-----------GNDPFAPSEGSAEAAP 491
++SPG A + TPT + + S + GS
Sbjct: 2622 TPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPS 2681
Query: 492 ELDLFAMKPPE--TSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTT 549
+ PP T+ +T T ST P +P P V A T AAT ++T T +
Sbjct: 2682 SSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAAT--SSTVTPS 2739
Query: 550 SAATATTAPPALDIFG-----DLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPV 604
SA T PP + L S+P A T + P G S
Sbjct: 2740 SALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSG--TLGTTHITEPSTGTSHT 2797
Query: 605 PESSLTADLLSVDAFAAPSPA--TTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASS 662
P ++ S A ++P P+ TT SP ++ G + + + + A S
Sbjct: 2798 PAATTGTTQHSTPALSSPHPSSRTTESPPSPGTT--------TPGHTRATSRTTATATPS 2849
Query: 663 SSASADLLAGFGGSFMAPSPSPVT 686
+ ++ LL +P+ +P+T
Sbjct: 2850 KTRTSTLLPS------SPTSAPIT 2867
Score = 69.7 bits (169), Expect = 1e-11
Identities = 111/460 (24%), Positives = 166/460 (36%), Gaps = 69/460 (15%)
Query: 305 SSPATTVTS-PNSTPAKTID----TSPPVDLFATASAAVPVST-------SKPSSDLLDL 352
S+PAT+ T+ P+STP T T+ +T S A P ST ++PS+
Sbjct: 2419 STPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVT 2478
Query: 353 QPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPT 412
P S+ A++ A A P TA + SS P A T PT
Sbjct: 2479 VPTGSTATASSTQATAGTPHV-STTATTPTVTSSKATPFSS-PGTATALPALRSTATTPT 2536
Query: 413 TTAEIATASASASTT-TTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAAL 471
T+ A S+S TT T ++ T A +S E S AT T ++
Sbjct: 2537 ATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSV 2596
Query: 472 DACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTP-TASTAPPVPATAPSP---AP 527
PS A L T+ P +P TA T P +T +P
Sbjct: 2597 --------ATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGS 2648
Query: 528 AVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSID 587
V ++ T T TTTTT+ AT + A P+ S+ + + P +
Sbjct: 2649 TVTPSSIPGTTHTPTVLTTTTTTVATGSMATPS---------SSTQTSGTPPSLTTTATT 2699
Query: 588 LFSTDAFSSPPQ--GASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDA 645
+ +T + ++P G +P+P T A +PA T+S S A
Sbjct: 2700 ITATGSTTNPSSTPGTTPIPPVLTT---------TATTPAATSSTVTPSS---------A 2741
Query: 646 FGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTP 705
G++ + P P + A + G S SP V A + T P
Sbjct: 2742 LGTTHTPPVPNTTATT-----------HGRSLSPSSPHTVRTAWTSATSGTLGTTHITEP 2790
Query: 706 STSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSP 745
ST +S + P+ G P ++ + + PPSP
Sbjct: 2791 STGTSHT--PAATTGTTQHSTPALSSPHPSSRTTESPPSP 2828
Score = 69.7 bits (169), Expect = 1e-11
Identities = 116/517 (22%), Positives = 176/517 (34%), Gaps = 104/517 (20%)
Query: 395 PSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAA 454
PS S P TP TT I T + +TTT T TA P++
Sbjct: 3675 PSTPATSSTATPSSTPGTTW--ILTKLTTTATTTESTGSTA---------------TPSS 3717
Query: 455 SEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETS---VPVVTP- 510
+ G T A + +G+ A S + P + A P TS P +P
Sbjct: 3718 TPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPG 3777
Query: 511 TASTAPPVPATAPSP-APAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFE 569
TA+ P + +TA +P A + A +++ T + TTT AT +TA P+
Sbjct: 3778 TATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPS--------- 3828
Query: 570 STPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTAS 629
STPE A + +T A ++ G+ P S+ P A T
Sbjct: 3829 STPETAHTST--------VLTTTATTTRATGSVATPSST-------------PGTAHTTK 3867
Query: 630 PAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSP-VTPA 688
++G + G++ + P S + +++ GS + PS P T
Sbjct: 3868 VPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTS---------GSTVTPSSVPGTTHT 3918
Query: 689 QNNLLQPNFEAAFGT--TPSTSSSSSFDP-------SVFDGLGDLLMPTMAPAGQPAPVS 739
L A G+ TPS+S+ +S P + G P+ P P P
Sbjct: 3919 PTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPV 3978
Query: 740 MVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKV 799
+ + AA+ SS + LG + T P
Sbjct: 3979 LTTTATTPAAT--------SSTVTPSSALGTTHTPPV--------------------PNT 4010
Query: 800 APATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMF 859
T + PS+P TS+ G + +P G PA T P +
Sbjct: 4011 TATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALS 4070
Query: 860 A-QPMMR----PPFGAAAVPGTQLSPSPTPASQSPKK 891
+ P R PP PG + S T A+ +P K
Sbjct: 4071 SPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSK 4107
Score = 68.6 bits (166), Expect = 3e-11
Identities = 114/473 (24%), Positives = 155/473 (32%), Gaps = 100/473 (21%)
Query: 299 PSPLSKSSPATT--VTSPNSTPAKTIDTSPPVDLFATASAA----VPVSTSKPSSDLLDL 352
P+ S+P TT +T P++T T+ T +T + A V ST+ + +
Sbjct: 3153 PTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSR 3212
Query: 353 QPDFSSGGAAAA------AAPAPP-------PPAGGATAWGDL------LGEDSLAALSS 393
SS G A A A P P + TAW L S A SS
Sbjct: 3213 ATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSS 3272
Query: 394 VPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPA 453
P S T T +AT S++ T T T F ++SPG A
Sbjct: 3273 TPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALT 3332
Query: 454 ASEGAAAPATPTPVAAALDACS--GNDPFAP---------SEGSAEAAPELDLFAMKPPE 502
+ TPT + + S G A + GS + PP
Sbjct: 3333 PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPS 3392
Query: 503 --TSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPA 560
T+ +T T ST P +P P V A T AAT ++T T +SA T PP
Sbjct: 3393 LTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAAT--SSTVTPSSALGTTHTPP- 3449
Query: 561 LDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPE--SSLTADLLSVDA 618
P A +T S PP V +S T+ +L
Sbjct: 3450 ----------VPNTTA-------------TTHGRSLPPSSPHTVRTAWTSATSGILGTTH 3486
Query: 619 FAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFM 678
PS T+ +PA S+ + S P P+S+ S
Sbjct: 3487 ITEPSTVTSHTPAATTST------TQHSTPALSSPHPSSRTTES---------------- 3524
Query: 679 APSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAP 731
PSP TP A TPS + +S+ PS PT AP
Sbjct: 3525 PPSPGTTTPGHTRGTSRTTATA---TPSKTRTSTLLPS---------SPTSAP 3565
Score = 67.8 bits (164), Expect = 4e-11
Identities = 108/454 (23%), Positives = 158/454 (34%), Gaps = 85/454 (18%)
Query: 305 SSPATTVTS-PNSTPAKT-IDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAA 362
S+PAT+ T+ P+STP T I T P TAS ST+ P+S L
Sbjct: 1890 STPATSSTATPSSTPGTTWILTKPTTTATTTASTG---STATPTSTL------------- 1933
Query: 363 AAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASA 422
APPP TA + S A SS P A T PT T+ S+
Sbjct: 1934 ---RTAPPPKVLTTTATTPTV-TSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSS 1989
Query: 423 SA---------STTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDA 473
S +TT T T TA + S A+ A + TP + A
Sbjct: 1990 SLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTA 2049
Query: 474 CSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAA 533
+ P + G A+ PP TPT + P++ P
Sbjct: 2050 HTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPG--------- 2100
Query: 534 AATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDA 593
T TA TTTTT+ AT + A P+ S+ + + P + + +T +
Sbjct: 2101 ---TTHTATVLTTTTTTVATGSMATPS---------SSTQTSGTPPSLTTTATTITATGS 2148
Query: 594 FSSPPQ--GASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSAS 651
++P G +P+P T A +PA T++ S A G++ +
Sbjct: 2149 TTNPSSTPGTTPIPPVLTT---------TATTPAATSNTVTPSS---------ALGTTHT 2190
Query: 652 EPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSS 711
P P + A + G S SP V A + T PST +S
Sbjct: 2191 PPVPNTMATT-----------HGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSH 2239
Query: 712 SFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSP 745
+ + G P ++ + + PPSP
Sbjct: 2240 TL--AATTGTTQHSTPALSSPHPSSRTTESPPSP 2271
Score = 67.0 bits (162), Expect = 8e-11
Identities = 95/445 (21%), Positives = 163/445 (36%), Gaps = 51/445 (11%)
Query: 305 SSPATT--VTSPNSTPAKTIDTSPPVDLFAT-ASAAVP-VSTSKPSSDLLDLQPDFSSGG 360
S+P TT +T P++T T+ T +T A+A P VST+ + + + SS
Sbjct: 4445 STPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSP 4504
Query: 361 AAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISD-PFAPEPTPPTTTAEIAT 419
A A PA A TA + +++PS + + + T PT T AT
Sbjct: 4505 GTATALPALRSTATTPTA----------TSFTAIPSSSLGTTWTRLSQTTTPTATMSTAT 4554
Query: 420 ASASASTTTTVTAVTAEVDLFG-DAFAASPGEAPAASEGAAAPATPTPVAAALDACSGND 478
S++ T T T +TA G A+P P + P T T A + S
Sbjct: 4555 PSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSS--- 4611
Query: 479 PFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTA 538
G+A P + + P T+ P + + T +P T
Sbjct: 4612 -----PGTA-LTPPVWISTTTTPTTTTPTTSGSTVTPSSIPG----------------TT 4649
Query: 539 ATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPP 598
TA TTTTT+ AT + A P+ S+ + + P + + +T + ++P
Sbjct: 4650 HTARVLTTTTTTVATGSMATPS---------SSTQTSGTPPSLTTTATTITATGSTTNPS 4700
Query: 599 QGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQ 658
P + + + A + +++SP + V+ +++ P P+S
Sbjct: 4701 STPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSST 4760
Query: 659 AASSSSASADLLAGFGG-SFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSV 717
++ + A S + S +P T + +L T + + SS+ +
Sbjct: 4761 LWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTR 4820
Query: 718 FDGLGDLLMPTMAPAGQPAPVSMVP 742
T A G A +S P
Sbjct: 4821 ILTELTTTATTTAATGSTATLSSTP 4845
Score = 66.6 bits (161), Expect = 1e-10
Identities = 149/672 (22%), Positives = 227/672 (33%), Gaps = 114/672 (16%)
Query: 297 GAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDF 356
G SP S+ T T +TPA + + + P A++ +P ++ P +
Sbjct: 1659 GLTSPRYTSTLGTATTGGPTTPAGSTEPTVP----GVATSTLPTRSALPGTT-------- 1706
Query: 357 SSGGAAAAAAPAPPP---PAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTT 413
G+ P+ PP P AT+ G S A S P ++ PT
Sbjct: 1707 ---GSLGTWRPSQPPTLAPTTMATSRARPTGTASTA--SKEPLTTSLA---------PTL 1752
Query: 414 TAEIATASASASTT---TTVTAVTAEVDLFGDAFAASPGE------APAASEGAAAPATP 464
T+E++T+ A ST TT++ +T G E + G A
Sbjct: 1753 TSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDME 1812
Query: 465 TPVAAALDACSGNDPFAPS--EGSAEAAPELDLFAMKPPETSVPVVTPTA---------- 512
T + A G +AP E AE PE+ + + T T
Sbjct: 1813 T--FENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFN 1870
Query: 513 ---------------STAPPVPATAPSPAPAVAAAAA------ATTAATAAATTTTTTSA 551
S P PAT+ + P+ TTA T A+T +T T
Sbjct: 1871 MCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPT 1930
Query: 552 ATATTAPPALDIFGDLFESTPEVAA-----APKPDAAPSIDLFSTDAFSSPPQGASPVPE 606
+T TAPP + +TP V + + P A ++ + A + +P+P
Sbjct: 1931 STLRTAPPPKVL--TTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPS 1988
Query: 607 SSLTADLLSVDAFAAP----SPATTAS-PAKVDSSGVIDLFGDAFGSSASEPQPASQAAS 661
SSL + P S AT +S P +S V+ G++ S P+S +
Sbjct: 1989 SSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGT 2048
Query: 662 SSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDG- 720
+ + G + PS SP T L P + TTP T+ S+ PS G
Sbjct: 2049 AHTTKVPTTTTTGFT-ATPSSSPGT-----ALTPPVWISTTTTP-TTRGSTVTPSSIPGT 2101
Query: 721 --LGDLLMPT--------MAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGI 770
+L T MA S PPS A+ + ++ +S G I
Sbjct: 2102 THTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPI 2161
Query: 771 ----SGTTTKKGDLQWNAGEKKLTGGANWQ--PKVAPATWSAGVPPSAPLQGAVPPTSSV 824
+ T T G + P T +PPS+P TS+
Sbjct: 2162 PPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSAT 2221
Query: 825 PPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFA-QPMMR----PPFGAAAVPGTQLS 879
+ G + +P A T P + + P R PP PG +
Sbjct: 2222 SGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTA 2281
Query: 880 PSPTPASQSPKK 891
S T A+ +P K
Sbjct: 2282 TSRTTATATPSK 2293
Score = 66.2 bits (160), Expect = 1e-10
Identities = 94/424 (22%), Positives = 142/424 (33%), Gaps = 76/424 (17%)
Query: 298 APSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFS 357
A +P SS AT +SP + ATA A+ + + P++ P S
Sbjct: 3760 ATTPTVTSSKATPFSSPGT---------------ATALPALRSTATTPTATSFTAIPSSS 3804
Query: 358 SGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEI 417
G + P A +T A SS P A S T T +
Sbjct: 3805 LGTTWTRLSQTTTPTATMST-----------ATPSSTPETAHTSTVLTTTATTTRATGSV 3853
Query: 418 ATASASASTTTTVTAVTAEVDLFGDAFAASPGEA------------PAASEGAAAPA--- 462
AT S++ T T T F ++SPG A P S P+
Sbjct: 3854 ATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVP 3913
Query: 463 ----TPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPV 518
TPT + + PS + + L T+ +T T ST P
Sbjct: 3914 GTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLI------TTATTITATGSTTNPS 3967
Query: 519 PATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFG-----DLFESTPE 573
+P P V A T AAT ++T T +SA T PP + L S+P
Sbjct: 3968 STPGTTPIPPVLTTTATTPAAT--SSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPH 4025
Query: 574 VAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPA--TTASPA 631
A T + P G S P ++ S A ++P P+ TT SP
Sbjct: 4026 TVRTAWTSATSG--TLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPP 4083
Query: 632 KVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNN 691
++ G + + + + A S + ++ LL +P+ +P+T
Sbjct: 4084 SPGTT--------TPGHTTATSRTTATATPSKTRTSTLLPS------SPTSAPITTVVTT 4129
Query: 692 LLQP 695
+P
Sbjct: 4130 GCEP 4133
Score = 65.9 bits (159), Expect = 2e-10
Identities = 109/502 (21%), Positives = 167/502 (33%), Gaps = 64/502 (12%)
Query: 387 SLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAA 446
S A SS P A T PT T+ AT+S+S T TT+ +T+
Sbjct: 4268 STATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVT 4327
Query: 447 SPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPET--S 504
+ + G T TPVA + P + A T S
Sbjct: 4328 PIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSS 4387
Query: 505 VP----VVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPA 560
P ++T + A AT P+ P ++ TT TTT TT+A+T +TA P+
Sbjct: 4388 TPGTTWILTELTTAATTTAATGPTATP---SSTPGTTWILTELTTTATTTASTGSTATPS 4444
Query: 561 LDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTA---DLLSVD 617
T + P A ++ ST A +S Q + P S TA + S
Sbjct: 4445 ST------PGTTWILTEPSTTATVTVPTGST-ATASSTQATAGTPHVSTTATTPTVTSSK 4497
Query: 618 AFAAPSPAT-TASPA------KVDSSGVIDLFGDAFG------SSASEPQPASQAASSSS 664
A + SP T TA PA ++ + + G S + P A+ SS
Sbjct: 4498 ATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSS 4557
Query: 665 -----------ASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSF 713
+ G GS PS +P T A + F TPS+S ++
Sbjct: 4558 TPETVHTSTVLTATATTTGATGSVATPSSTPGT-AHTTKVPTTTTTGFTATPSSSPGTAL 4616
Query: 714 DPSVFDGLGDLLMPTM---APAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGI 770
P V+ + PT +G S +P + A L + +
Sbjct: 4617 TPPVW--ISTTTTPTTTTPTTSGSTVTPSSIPGTTHTA----------RVLTTTTTTVAT 4664
Query: 771 SGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGA 830
T Q + LT A T + P + P+ + T++ P +
Sbjct: 4665 GSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSS 4724
Query: 831 PSVGQPGAGFGMPPAGTGMPMM 852
+ P T +P++
Sbjct: 4725 KATSS-----SSPRTATTLPVL 4741
Score = 65.9 bits (159), Expect = 2e-10
Identities = 99/475 (20%), Positives = 165/475 (34%), Gaps = 59/475 (12%)
Query: 298 APSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVS-----------TSKPS 346
A +P SS AT +SP + A S AT+ A+P S T+ P+
Sbjct: 4488 ATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPT 4547
Query: 347 SDLLDLQPD----------------FSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAA 390
+ + P ++G + A P+ P T A
Sbjct: 4548 ATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTAT 4607
Query: 391 LSSVPSEA-----QISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFA 445
SS P A IS P T PTT+ T S+ TT T +T
Sbjct: 4608 PSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSM 4667
Query: 446 ASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSV 505
A+P ++++ + P + T A + A + + G+ P L A P TS
Sbjct: 4668 ATPS---SSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSS 4724
Query: 506 PVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFG 565
T+S++P T P + A + ++T TT + TT P
Sbjct: 4725 KA---TSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTP------- 4774
Query: 566 DLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSL-TADLLSVDAFAAPSP 624
+ + + P+ + + +T A + ++ P S+L T +L+ A +
Sbjct: 4775 --MSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTT 4832
Query: 625 ATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSP-- 682
A T S A + S+ + A+ P A++SS + MA P
Sbjct: 4833 AATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTA 4892
Query: 683 -SPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPA 736
+ P+ + + A ++ T S S+ SV + T+ P G P+
Sbjct: 4893 TASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSV--------LTTLRPTGFPS 4939
Score = 63.9 bits (154), Expect = 6e-10
Identities = 104/445 (23%), Positives = 159/445 (35%), Gaps = 47/445 (10%)
Query: 395 PSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAA 454
PS S P TP TT I T + +TTT T TA +++PG AP
Sbjct: 4232 PSTPATSSTAMPSSTPGTTW--ILTELTTTATTTASTGSTATP-------SSTPGTAPPP 4282
Query: 455 SEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTAST 514
+PAT TP A + A S + P +A P L A K TSV TP S+
Sbjct: 4283 KV-LTSPAT-TPTATSSKATSSSSP-----RTATTLPVLTSTATKSTATSV---TPIPSS 4332
Query: 515 APPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEV 574
T P A + ++ TT T+T T T A STP
Sbjct: 4333 TLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATS-----STSTPSS 4387
Query: 575 AAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVD 634
+T A + P S P ++ L+ A S +TA+P+
Sbjct: 4388 TPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTP 4447
Query: 635 SSGVIDLFGDAFGSSASEPQPASQAASSSSASAD--------LLAGFGGSFMAPSPSPVT 686
+ I L + ++ + P ++ ASS+ A+A S PS SP T
Sbjct: 4448 GTTWI-LTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGT 4506
Query: 687 PAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPA 746
L+ + TTP+ +S ++ S L T P +M +P+
Sbjct: 4507 ATALPALR-----STATTPTATSFTAIPSSSLGTTWTRLSQTTTPT-----ATMSTATPS 4556
Query: 747 MAASKALGSDLDSSLASLVGNLG-ISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWS 805
S + ++ A+ G G ++ ++ G T G P +P T
Sbjct: 4557 STPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGT-- 4614
Query: 806 AGVPPSAPLQGAVPPTSSVPPVAGA 830
+ P + PT++ P +G+
Sbjct: 4615 -ALTPPVWISTTTTPTTTTPTTSGS 4638
Score = 63.5 bits (153), Expect = 8e-10
Identities = 150/689 (21%), Positives = 234/689 (33%), Gaps = 107/689 (15%)
Query: 268 TQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPP 327
T A +S T L T N + LS SSP T T+ S + T+ T+
Sbjct: 3985 TPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI 4044
Query: 328 VDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDS 387
+ +T ++ P +T+ + P SS ++ +PP P G T G
Sbjct: 4045 TEP-STGTSHTPAATTGTTQHST---PALSSPHPSSRTTESPPSP--GTTTPGHTTATSR 4098
Query: 388 LAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVT--------AEVDL 439
A ++ PS+ + S PT T + T + + + D
Sbjct: 4099 TTA-TATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDT 4157
Query: 440 FGDAFAASPG--EAPAASE--GAAAPATPTPVAAALDACS-------------------- 475
+ + AA E P E A P P + CS
Sbjct: 4158 YSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCF 4217
Query: 476 -----------GNDPFAPSEGSAEAAPELD--LFAMKPPETSVPVVTPTASTAPPVPATA 522
G+ P P+ S + + T+ T STA P
Sbjct: 4218 NYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPG 4277
Query: 523 PSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDA 582
+P P V + A T AT ++ T+++S TATT P + ST + A
Sbjct: 4278 TAPPPKVLTSPATTPTAT-SSKATSSSSPRTATTLP--------VLTSTATKSTATSVTP 4328
Query: 583 APSIDLFSTDAFSSPPQGASPV-----------PESSLTADLLSVDAFAAPSPATTASPA 631
PS L +T P Q +PV PE++ T+ +L+ A + ++T++P+
Sbjct: 4329 IPSSTLGTTGTL--PEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPS 4386
Query: 632 KVDSSGVI--DLFGDAFGSSASEP------QPASQAASSSSASADLLAGFGGSFMAPSPS 683
+ I +L A ++A+ P P + + + GS PS +
Sbjct: 4387 STPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSST 4446
Query: 684 PVTPAQNNLLQPNFEAAFGT-TPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVP 742
P T L +P+ A T ST+++SS T A AG P VS
Sbjct: 4447 PGTTW--ILTEPSTTATVTVPTGSTATASS---------------TQATAGTP-HVSTTA 4488
Query: 743 PSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPA 802
+P + +SKA S + +L + T T + T Q A
Sbjct: 4489 TTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTA 4548
Query: 803 TWSAGVPPSAP--LQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFA 860
T S P S P + + T++ SV P + G A T A
Sbjct: 4549 TMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPG--TAHTTKVPTTTTTGFTA 4606
Query: 861 QPMMRPPFGAAAVPGTQLSPSPTPASQSP 889
P P G A P +S + TP + +P
Sbjct: 4607 TPSSSP--GTALTPPVWISTTTTPTTTTP 4633
Score = 62.8 bits (151), Expect = 1e-09
Identities = 77/339 (22%), Positives = 122/339 (35%), Gaps = 34/339 (10%)
Query: 259 IDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTP 318
+ IP T L T + + SG P L+ ++ T T + P
Sbjct: 4640 VTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNP 4699
Query: 319 AKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATA 378
+ T T+P + T++A P +TS ++ SS A P A +TA
Sbjct: 4700 SSTPGTTPITPVL-TSTATTPAATSSKATS--------SSSPRTATTLPVLTSTATKSTA 4750
Query: 379 WGDLLGEDSLAALSSVPSEAQISDPFAP-EPTPPTTTAEIATASASASTTTTVTAVTAEV 437
+ + +PS + P + T P +T S++ TT T T +T
Sbjct: 4751 ----------TSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTA 4800
Query: 438 DLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFA 497
+ A + P+++ G T A A +G S + + P +
Sbjct: 4801 TM---TRATNSTATPSSTLGTTRILTELTTTATTTAATG------STATLSSTPGTT-WI 4850
Query: 498 MKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTA 557
+ P T V+ PT STA + P V A ATA+ +++T T T A
Sbjct: 4851 LTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPA 4910
Query: 558 --PPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAF 594
P +L F + + V +P PS FST F
Sbjct: 4911 VLPSSLPTF-SVSTVSSSVLTTLRPTGFPS-SHFSTPCF 4947
Score = 62.0 bits (149), Expect = 2e-09
Identities = 89/399 (22%), Positives = 141/399 (35%), Gaps = 58/399 (14%)
Query: 296 SGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVS-----------TSK 344
S A +P SS AT +SP + A S AT+ A+P S T+
Sbjct: 3201 STATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTT 3260
Query: 345 PSSDLLDLQPD----------------FSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSL 388
P++ + P ++ + A P+ P T
Sbjct: 3261 PTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFT 3320
Query: 389 AALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASP 448
A SS P A + T PTT T S+ TT T T +T A+P
Sbjct: 3321 ATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATP 3380
Query: 449 GEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVV 508
++++ + P + T A + A + + G+ P L A P TS V
Sbjct: 3381 S---SSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATS-STV 3436
Query: 509 TPTAST----APPVPATAPS-------PAPAVAAAAAATTAATAAATTTTTTSAATATTA 557
TP+++ PPVP T + P+ A T+A + TT T +T T+
Sbjct: 3437 TPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSH 3496
Query: 558 PPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVD 617
PA STP + ++P P S+ SPP + P + +
Sbjct: 3497 TPAATT-STTQHSTPAL-SSPHP---------SSRTTESPPSPGTTTPGHTRGTSRTTAT 3545
Query: 618 AFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPA 656
A + + +T P+ S+ + + ++ EPQ A
Sbjct: 3546 ATPSKTRTSTLLPSSPTSAPITTVV-----TTGCEPQCA 3579
Score = 59.7 bits (143), Expect = 1e-08
Identities = 164/770 (21%), Positives = 243/770 (31%), Gaps = 149/770 (19%)
Query: 259 IDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTP 318
+ IP T + L T + + SG P L+ ++ T T + P
Sbjct: 2093 VTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNP 2152
Query: 319 AKTIDTSPPVDLFATASAAVPVSTSK---PSSDLLDLQ-PDFSSGGAAAAAAPAPPP-PA 373
+ T T+P + T +A P +TS PSS L P + A PP P
Sbjct: 2153 SSTPGTTP-IPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPH 2211
Query: 374 GGATAW----GDLLG----------------------EDSLAALSSV-PSEAQISDPFAP 406
TAW +LG + S ALSS PS P +P
Sbjct: 2212 TVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSP 2271
Query: 407 EPTPP--TTTAEIATASASASTT---------------TTVTAVTAE--------VDLFG 441
T P TT TA+A+ S T TTV + E +D
Sbjct: 2272 GTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSY 2331
Query: 442 DAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSA---EAAPELDLFAM 498
S G+ S AA L+ + P P E + + L
Sbjct: 2332 PMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCR 2391
Query: 499 KPPETS---------VPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTT 549
+ + V P PAT+ + P+ + TT TTT TT
Sbjct: 2392 NREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPS---STPGTTWILTELTTTATT 2448
Query: 550 SAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSL 609
+ +T +TA P+ T + P A ++ ST A +S Q + P S
Sbjct: 2449 TESTGSTATPSST------PGTTWILTEPSTTATVTVPTGST-ATASSTQATAGTPHVST 2501
Query: 610 TADLLSVDA-----FAAPS-----PATTASPAKVDSSGVIDLFGDAFG------SSASEP 653
TA +V + F++P PA ++ ++ + + G S + P
Sbjct: 2502 TATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP 2561
Query: 654 QPASQAASSSS-----------ASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFG 702
A+ SS + G GS PS +P T +L F
Sbjct: 2562 TATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTT-TTGFT 2620
Query: 703 TTPSTSSSSSFDPSVFDGL-------GDLLMPTMAPAGQPAP-------VSMVPPSPAMA 748
TPS+S ++ V+ G + P+ P P ++ S A
Sbjct: 2621 ATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATP 2680
Query: 749 ASKALGSDLDSSLASLVGNLGISGTTTKKGD----------LQWNAGEKKLTG------- 791
+S S SL + + +G+TT L A T
Sbjct: 2681 SSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSS 2740
Query: 792 --GANWQPKV---APATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAG 846
G P V T + PS+P TS+ G + +P G PA
Sbjct: 2741 ALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAA 2800
Query: 847 TGMPMMPQQPVMFA-QPMMR----PPFGAAAVPGTQLSPSPTPASQSPKK 891
T P + + P R PP PG + S T A+ +P K
Sbjct: 2801 TTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSK 2850
Score = 54.7 bits (130), Expect = 4e-07
Identities = 148/726 (20%), Positives = 232/726 (31%), Gaps = 106/726 (14%)
Query: 259 IDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTP 318
+ IP T P+ L T + + SG P L+ ++ T T + P
Sbjct: 2650 VTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNP 2709
Query: 319 AKTIDTSPPVDLFATASAAVPVSTSK---PSSDL--LDLQPDFSSGGAAAAAAPAPPPPA 373
+ T T+P + T +A P +TS PSS L P ++ + +P P
Sbjct: 2710 SSTPGTTP-IPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPH 2768
Query: 374 GGATAW----GDLLG----------------------EDSLAALSSV-PSEAQISDPFAP 406
TAW LG + S ALSS PS P +P
Sbjct: 2769 TVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSP 2828
Query: 407 EPTPP-----------------TTTAEIATASASASTTTTVTAVTAE--------VDLFG 441
T P T T+ + +S +++ TTV + E +D
Sbjct: 2829 GTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSY 2888
Query: 442 DAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSA---EAAPELDLFAM 498
S G+ S AA L+ + P P E + + L
Sbjct: 2889 PMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCR 2948
Query: 499 KPPETS---------VPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTT 549
+ + V P PAT+ + P+ + TT TT TT
Sbjct: 2949 NREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPS---STPGTTWILTEQTTAATT 3005
Query: 550 SAATATTAPPALDIFGDLFESTPEVAAAPK---PDAAPSIDLFSTDAFSSPPQGASPVPE 606
+A T +TA P+ STP A PK A S SS P+ A+ +P
Sbjct: 3006 TATTGSTAIPS---------STPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPV 3056
Query: 607 SSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSAS 666
+ TA + +F T + + + + +S P+ + ++ +
Sbjct: 3057 LTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKA 3116
Query: 667 ADLLAGFGGSFMAPSPSP--------VTPAQNNLLQPNFEAAFGTTPSTS-----SSSSF 713
A S PS +P +T A A +TP T+ S++
Sbjct: 3117 TTTRA--TSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTA 3174
Query: 714 DPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGT 773
+V G T A AG ++ +P + +S+A S + +L + T
Sbjct: 3175 TVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATT 3234
Query: 774 TTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAP--LQGAVPPTSSVPPVAGAP 831
T + Q AT S P S P + + T++
Sbjct: 3235 PTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATG 3294
Query: 832 SVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKK 891
SV P + G A T A P P G A P +S + TP ++
Sbjct: 3295 SVATPSSTPG--TAHTTKVPTTTTTGFTATPSSSP--GTALTPPVWISTTTTPTTRGSTV 3350
Query: 892 PPAKDP 897
P+ P
Sbjct: 3351 TPSSIP 3356
Score = 50.8 bits (120), Expect = 6e-06
Identities = 75/310 (24%), Positives = 118/310 (38%), Gaps = 30/310 (9%)
Query: 268 TQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSS--------PATTVTSPNSTPA 319
T PSS ET H +T+ +G+ + S + P TT T TP+
Sbjct: 3824 TATPSSTPETA--HTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPS 3881
Query: 320 KTIDTS--PPVDLFATASAAVPVSTSKPSS-DLLDLQPDFSSGGAAAAAAPAPPPPAGGA 376
+ T+ PPV + T + ST PSS P + A + P+
Sbjct: 3882 SSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSST 3941
Query: 377 TAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAE 436
G + +++ + ++P + T P TA+ A+T++TVT +A
Sbjct: 3942 QTSGT--PPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSA- 3998
Query: 437 VDLFGDAFAASPGEAPAASEGAA-APATPTPVAAA-LDACSGN----DPFAPSEGSAEA- 489
G A + G + +P++P V A A SG PS G++
Sbjct: 3999 ---LGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTP 4055
Query: 490 APELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTA-ATAAATTTTT 548
A P S P + + +PP P T P A + TTA AT + T T+T
Sbjct: 4056 AATTGTTQHSTPALSSPHPSSRTTESPPSPGTT---TPGHTTATSRTTATATPSKTRTST 4112
Query: 549 TSAATATTAP 558
++ T+AP
Sbjct: 4113 LLPSSPTSAP 4122
Score = 47.8 bits (112), Expect = 5e-05
Identities = 131/701 (18%), Positives = 218/701 (31%), Gaps = 119/701 (16%)
Query: 259 IDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTP 318
+ IP T + L T + + SG P L+ ++ T T + P
Sbjct: 3350 VTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNP 3409
Query: 319 AKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATA 378
+ T T+ P+ T +A P +TS + +A PP P AT
Sbjct: 3410 SSTPGTT-PIPPVLTTTATTPAATSSTVTP-----------SSALGTTHTPPVPNTTATT 3457
Query: 379 WGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVD 438
G L S + + + A T P+T T+ A+TT+T T +
Sbjct: 3458 HGRSLPPSSPHTVRTAWTSATSGILGTTHITEPST----VTSHTPAATTSTTQHSTPAL- 3512
Query: 439 LFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAM 498
+SP + +E +P T TP S +A A P +
Sbjct: 3513 -------SSPHPSSRTTESPPSPGTTTP----------GHTRGTSRTTATATPSKTRTST 3555
Query: 499 KPPE--TSVPVVTPTASTAPPVPA-------TAPSPAPAVA-AAAAATTAATAAATTTTT 548
P TS P+ T + P A + P P P+ + A A
Sbjct: 3556 LLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQP 3615
Query: 549 TSAATATTAPPALDI--FGDLFE------------------------------------- 569
A P + + G + E
Sbjct: 3616 LGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCP 3675
Query: 570 STPEVAAAPKPDAAPS----IDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPA 625
STP ++ P + P + +T A ++ G++ P S+ + + P+
Sbjct: 3676 STPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTE------PS 3729
Query: 626 TTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPV 685
TTA+ V G +S+++ + S+++ + + + F +P +
Sbjct: 3730 TTAT--------VTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATA 3781
Query: 686 TPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQP--APVSMVPP 743
PA + +F PS+S +++ M T P+ P A S V
Sbjct: 3782 LPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLT 3841
Query: 744 SPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPAT 803
+ A ++A GS S + TTT G + G A P T
Sbjct: 3842 TTA-TTTRATGSVATPSSTPGTAHTTKVPTTTTTG---FTVTPSSSPGTARTPPVWISTT 3897
Query: 804 WSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFA--- 860
+ S +VP T+ P V + P + T P + A
Sbjct: 3898 TTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTI 3957
Query: 861 -------QPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPA 894
P P G +P + + TPA+ S P+
Sbjct: 3958 TATGSTTNPSSTP--GTTPIPPVLTTTATTPAATSSTVTPS 3996
Score = 40.8 bits (94), Expect = 0.006
Identities = 39/149 (26%), Positives = 59/149 (39%), Gaps = 7/149 (4%)
Query: 409 TPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVA 468
TPP TT E+ TA+ + + T A AS P SEG +P
Sbjct: 1612 TPPPTT-ELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPR----YT 1666
Query: 469 AALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTAST-APPVPATAPSPAP 527
+ L + P P+ + P + + P +++P T + T P P T
Sbjct: 1667 STLGTATTGGPTTPAGSTEPTVPGVATSTL-PTRSALPGTTGSLGTWRPSQPPTLAPTTM 1725
Query: 528 AVAAAAAATTAATAAATTTTTTSAATATT 556
A + A TA+TA+ TT+ A T T+
Sbjct: 1726 ATSRARPTGTASTASKEPLTTSLAPTLTS 1754
Score = 39.7 bits (91), Expect = 0.013
Identities = 48/173 (27%), Positives = 71/173 (41%), Gaps = 16/173 (9%)
Query: 388 LAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAAS 447
L ++ ++A S P P +P T A A+ +A + + +T+ L G A
Sbjct: 1619 LETATTTTTQALFSTP-QPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTL-GTATTGG 1676
Query: 448 PGEAPAASEGAAAPATPT---PVAAALDACSGN-DPFAPSEGSAEAAPELDLFAMKPPET 503
P PA S P T P +AL +G+ + PS+ A + +P
Sbjct: 1677 P-TTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRARP--- 1732
Query: 504 SVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATT 556
T TASTA P T S AP + + + + A T+ T TT S T TT
Sbjct: 1733 -----TGTASTASKEPLTT-SLAPTLTSELSTSQAETSTPRTETTMSPLTNTT 1779
Score = 34.3 bits (77), Expect = 0.54
Identities = 43/189 (22%), Positives = 57/189 (30%), Gaps = 19/189 (10%)
Query: 522 APSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPD 581
A +P P A TT A +T TS+ T APPA ST V +
Sbjct: 1610 ATTPPPTTELETATTTTTQALFSTPQPTSSPGLTRAPPA---------STTAVPTLSEGL 1660
Query: 582 AAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPS----PATTASPAKVDSSG 637
+P T + G P S + V P+ P TT S S
Sbjct: 1661 TSPRY----TSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQ 1716
Query: 638 VIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQP-- 695
L +S + P + AS + L TP + P
Sbjct: 1717 PPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLT 1776
Query: 696 NFEAAFGTT 704
N + GTT
Sbjct: 1777 NTTTSQGTT 1785
>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
Length = 2639
Score = 82.4 bits (202), Expect = 2e-15
Identities = 124/584 (21%), Positives = 195/584 (33%), Gaps = 56/584 (9%)
Query: 268 TQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKT-IDTSP 326
T P+S T + T P +G +P + TT +P TP T T+
Sbjct: 1325 TPTPTSTQSTTPTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1383
Query: 327 PVDLFATASAA-VPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGE 385
P+ T + P T P+S + P P G T +
Sbjct: 1384 PITTTTTVTPTPTPTGTQTPTSTPI----------TTTTTVTPTPTPTGTQTPTTTPITT 1433
Query: 386 DSLAALSSVPSEAQISDPFAPEPTPPTTTAEIA-TASASASTTTTVTAVTAEVDLFGDAF 444
+ + P+ Q AP PT TTT+ + T + + + T T T +T
Sbjct: 1434 TTTVTPTPTPTGTQ-----APTPTAITTTSTVTPTPTPTGTQTPTTTPITTTT------- 1481
Query: 445 AASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETS 504
+P P ++ TPTP A P + + P + P T
Sbjct: 1482 TVTPTPTPTGTQ------TPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTP--TP 1533
Query: 505 VPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIF 564
P T T + P T +P P TT TT T T T T P +
Sbjct: 1534 TPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTV--- 1590
Query: 565 GDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFA---- 620
L +T + P P + S + T ++ A+P P + T ++ +
Sbjct: 1591 --LITTTTTMTPTPTPTSTKSTTV--TPITTTTTVTATPTPTGTQTPTMIPISTTTTVTP 1646
Query: 621 APSPAT--TASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSF- 677
P+P T T P ++ + +L +S PQ + +S + S LL+ +
Sbjct: 1647 TPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIE 1706
Query: 678 MAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAP 737
M + P TP PST++S P+ G PT +
Sbjct: 1707 MTSTAPPSTPTAPTTTSGGH--TLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTT 1764
Query: 738 VSMVP-PSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNA--GEKKLTGGAN 794
+ P P+P S + L +S++ ++ T G+ +N G+ +
Sbjct: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
Query: 795 WQPKVAPATWSAGVPPS-APLQGAVPPTSSVPPVAGAPSVGQPG 837
+ WS PS P PT S P + PS PG
Sbjct: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKP--SSTPSKPTPG 1866
Score = 69.3 bits (168), Expect = 2e-11
Identities = 105/513 (20%), Positives = 162/513 (31%), Gaps = 98/513 (19%)
Query: 406 PEPTPPTTTAEI----ATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAP 461
P PTP TTT + S ++T T +T T +P P + P
Sbjct: 1311 PTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1370
Query: 462 ATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPAT 521
TPTP + P + P T P T T ++ P T
Sbjct: 1371 -TPTPTGTQTPTTT------PITTTTTVTP-----------TPTPTGTQTPTSTPITTTT 1412
Query: 522 APSPAPAVAAAAAATTAATAAATTTTTTSAATATTAP-PALDIFGDLFESTPEVAAAPKP 580
+P P TT TT T T T T AP P TP P
Sbjct: 1413 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTP 1472
Query: 581 DAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAK--VDSSGV 638
P + +P +P P TA + P+P T +P + ++
Sbjct: 1473 TTTPITTTTTVTPTPTPTGTQTPTP----TAITTTTTVTPTPTPTGTQTPTSTPITTTTT 1528
Query: 639 IDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPV---TPAQNNLLQP 695
+ G+ P P S + + P+P+P TP
Sbjct: 1529 VTPTPTPTGTQTPTPTPISTTTT----------------VTPTPTPTGTQTPT------- 1565
Query: 696 NFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVS-MVPPSPAMAASKALG 754
TTP T++++ + PT P G P + ++ + M +
Sbjct: 1566 -------TTPITTTTT-------------VTPTPTPTGTQTPTTVLITTTTTMTPTPTPT 1605
Query: 755 SDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVP---PS 811
S +++ + ++ T T G ++ P P T S G P +
Sbjct: 1606 STKSTTVTPITTTTTVTATPTPTG--TQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTST 1663
Query: 812 APLQGAVPPTSSVPPVAGAPSVGQPGAG---------FGMPPA----GTGMPMMPQQPVM 858
AP+ A TS+ PP + P + + +PPA T P P P
Sbjct: 1664 API--AELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTT 1721
Query: 859 FA--QPMMRPPFGAAAVPGTQLSPSPTPASQSP 889
+ + PP + PGT + T +S +P
Sbjct: 1722 TSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAP 1754
Score = 50.4 bits (119), Expect = 7e-06
Identities = 80/412 (19%), Positives = 122/412 (29%), Gaps = 67/412 (16%)
Query: 503 TSVPVVTPTASTAPPVPATAPS--PAPAVAAAAAATTAATAAATTTTTTSAATATTAPPA 560
T P+ T T T P P + S P P T T TTT T TT P
Sbjct: 1312 TPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP- 1370
Query: 561 LDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFA 620
TP P P I +T + P G + +T +
Sbjct: 1371 ----------TPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTSTPITT---TTTVTP 1416
Query: 621 APSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAP 680
P+P T +P + + + P P + +S+ G P
Sbjct: 1417 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTG----TQTP 1472
Query: 681 SPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVS- 739
+ +P+T P TP+ ++++ + PT P G P S
Sbjct: 1473 TTTPITTTTTVTPTPTPTGTQTPTPTAITTTT-----------TVTPTPTPTGTQTPTST 1521
Query: 740 ------MVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGA 793
V P+P ++ S+ ++ +GT T
Sbjct: 1522 PITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQT------------------ 1563
Query: 794 NWQPKVAPATWSAGVPPSAPLQGAVPPT----SSVPPVAGAPSVGQPGAGFGMPPAGTGM 849
P P T + V P+ G PT ++ + P+ + P T
Sbjct: 1564 ---PTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTT 1620
Query: 850 PMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDPLADL 901
P P M P V T P+PT S P + P+A+L
Sbjct: 1621 VTATPTPTGTQTPTMIPISTTTTVTPT---PTPTTGSTGPPTHTSTAPIAEL 1669
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 82.4 bits (202), Expect = 2e-15
Identities = 144/626 (23%), Positives = 208/626 (33%), Gaps = 98/626 (15%)
Query: 292 NNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLD 351
+N + + S +S + PA V S + + + +S A S ++P + L+
Sbjct: 548 SNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVP 607
Query: 352 -LQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTP 410
L P A+ P+PP P P P P P P
Sbjct: 608 PLSPQPKIVTPYTASQPSPPLPP---------------------PPPPPPPPPPPPPPPP 646
Query: 411 PTTTAEIATASASASTT----TTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTP 466
P ++ A ++ SA+ +T+T + G F P P + P P
Sbjct: 647 PPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALF--KPPTPPVMQSQSVKPQILVP 704
Query: 467 VAAALDACSGNDPFAPSEGSAEA-------APELDLFAMKPPETSVPVVTPTASTAPPVP 519
+ P P+ GSA A AP L F+ PP + V APP P
Sbjct: 705 PNGVVPPPPPPPP-PPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTP 763
Query: 520 ATAPS-PAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAP 578
P PAP A A T+T T + APP TP V A
Sbjct: 764 PPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPT---------PTPPVPPAK 814
Query: 579 KPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGV 638
K A P ++ SPP PVP +L +F A P + SP V
Sbjct: 815 KQPAFP-----ASYIPPSPPTPPVPVPPPTLPKQ----QSFCAKPPPSPLSPV----PSV 861
Query: 639 IDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFE 698
+ F + P SQ A+ +AP P A +P ++
Sbjct: 862 VKQIASQFPPPPTPPAMESQPLKPVPAN-----------VAPQSPPAVKA-----KPKWQ 905
Query: 699 AAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLD 758
+ P S F P + L+ P P+ PAP PP P AS D
Sbjct: 906 PSSIPVP----SPDFPPPPPE--SSLVFPPPPPSPVPAP----PPPPPPTASPT--PDKS 953
Query: 759 SSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAV 818
S G Q N+ K +G + +PK P+ S + P +
Sbjct: 954 GSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPK-RPSVDSLVSKFTPPAESGS 1012
Query: 819 PPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQL 878
P ++PP A P G+ + +G +P + QQ + A+ P
Sbjct: 1013 PSKETLPPPAAPPKPGK------LNLSGVNLPGVLQQGCVSAK---APVLSGRGKDSVVE 1063
Query: 879 SPSPTPASQSPKKPPAKD-PLADLNI 903
PSP S P PP + PL + I
Sbjct: 1064 FPSPPSDSDFPPPPPETELPLPPIEI 1089
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 80.9 bits (198), Expect = 5e-15
Identities = 150/666 (22%), Positives = 208/666 (31%), Gaps = 116/666 (17%)
Query: 258 GIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNST 317
G+D GD T S+ + KP N S P+ S +S T++T T
Sbjct: 91 GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPN--SDTSKETSLTVNKET 148
Query: 318 PAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGAT 377
+T +T+ +T S + S ++ + A + A P P T
Sbjct: 149 TVETKETTTTNKQTSTDGKEKTTSAKETQS----IEKTSAKDLAPTSKVLAKPTPKAETT 204
Query: 378 AWGDLLGEDSLAALSSVPSEAQISDPFAP-------------EPTPPTTTAEIATASASA 424
G L + P E + P P EP P TT + T A
Sbjct: 205 TKGPALTTPK-EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA 263
Query: 425 STTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATP------TPVAAALDACSGND 478
TTT A T + A + + PA + +AP TP TP A
Sbjct: 264 PTTTKEPAPTTPKEP-----APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 318
Query: 479 PFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTA 538
P P E + E +P T+ PTA P P T PAP A TT
Sbjct: 319 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP-APTTPKEPAPTTPKEPAPTTT 377
Query: 539 ATAAATTT-----TTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDA 593
+ TT TTT +A TT PA +AP PS A
Sbjct: 378 KEPSPTTPKEPAPTTTKSAPTTTKEPA----------PTTTKSAPTTPKEPSPTTTKEPA 427
Query: 594 FSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEP 653
++P + A P+ P+P T PA ++ EP
Sbjct: 428 PTTPKEPAPTTPKK--------------PAPTTPKEPAP---------------TTPKEP 458
Query: 654 QPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSF 713
P + + + + P+P TP + P TP+T +
Sbjct: 459 APTTTKKPAPTTPKE-------------PAPTTPKETAPTTPK-----KLTPTTPEKLA- 499
Query: 714 DPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGT 773
P+ + +AP P P PA KA + A
Sbjct: 500 -PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE--PAP 556
Query: 774 TTKKGDLQWNAGEKKLTGGANWQPK-VAPATWSAGVP--PSAPLQGAVPPTSSVPPVAGA 830
TT K E T PK AP T P P P + PT++ P +
Sbjct: 557 TTPKEPAPTTPKETAPT-----TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 611
Query: 831 PSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPK 890
P P GT P P++P P P T P+PT +PK
Sbjct: 612 CDKPAPTT-----PKGTA-PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT----TPK 661
Query: 891 KPPAKD 896
KP K+
Sbjct: 662 KPAPKE 667
Score = 73.2 bits (178), Expect = 1e-12
Identities = 87/358 (24%), Positives = 121/358 (33%), Gaps = 35/358 (9%)
Query: 298 APSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPS----SDLLDLQ 353
AP+ K +P T +TP +T T+P T P + KP+ +L
Sbjct: 459 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 518
Query: 354 PDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTT 413
P+ + AP P A T + P E + P P PT P
Sbjct: 519 PEEPTPTTPEEPAPTTPKAAAPNTP---------KEPAPTTPKEPAPTTPKEPAPTTPKE 569
Query: 414 TAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDA 473
TA T +A TT A T A + + P ++ PA TP A
Sbjct: 570 TAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT-CDKPAPTTPKGTAPTT 627
Query: 474 CSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAP-----PVPATAPSPAPA 528
P P E + +K P + P AP P T+ PAP
Sbjct: 628 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 687
Query: 529 VAAAAAATTAATAAATT-------------TTTTSAATATTAPPALDIFGDLFESTPEVA 575
A TT A TT TT+ +T TT I ESTPE++
Sbjct: 688 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 747
Query: 576 AAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKV 633
A P P A + + P A+ PE + TA + + +P TT + K+
Sbjct: 748 AEPTPKALENSPKEPGVPTTKTP--AATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 803
Score = 72.0 bits (175), Expect = 2e-12
Identities = 107/467 (22%), Positives = 151/467 (32%), Gaps = 38/467 (8%)
Query: 288 KKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKP-- 345
K+P AP+ + +P TT ++P +TP + T+ T P +T +P
Sbjct: 230 KEPTPTTIKSAPTTPKEPAPTTTKSAP-TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 288
Query: 346 ----SSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQIS 401
S+ +P ++ A P P P E + P+ +
Sbjct: 289 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 348
Query: 402 DPFAPEPTPPTTTAEIA--TASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAA 459
P AP+ PTT E A T A TTT + T +P E PA + +
Sbjct: 349 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT------------TPKE-PAPTTTKS 395
Query: 460 APATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVP 519
AP T A + P P E S E K P + P + P P
Sbjct: 396 APTTTKEPAPTTTKSA---PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 452
Query: 520 ATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPK 579
T PAP A TT A TT T+ T P L +TPE A
Sbjct: 453 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP--EKLAPTTPEKPAPTT 510
Query: 580 P-DAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGV 638
P + AP+ T P +P + T + P+P T PA
Sbjct: 511 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 570
Query: 639 IDLFGDAFG-SSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNF 697
++ EP P + + A S P+P TP P
Sbjct: 571 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 630
Query: 698 EAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPA--GQPAPVSMVP 742
A TTP + P+ G + AP +PAP + P
Sbjct: 631 PAP--TTPKEPA-----PTTPKGTAPTTLKEPAPTTPKKPAPKELAP 670
Score = 70.9 bits (172), Expect = 5e-12
Identities = 130/581 (22%), Positives = 179/581 (30%), Gaps = 111/581 (19%)
Query: 367 PAPPPP----AGGATAWGDL---LGEDSLAALSSVPSEAQISD--PFAPEPTPPTTTAEI 417
P P PP AG GD + S + V + +I+ P P P+ P +
Sbjct: 78 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 137
Query: 418 ATASASASTTTTV-----TAVTAEVDLFGDAFAASPGEAPAASEGAA---AP-----ATP 464
S + + TTV T + G S E + + +A AP A P
Sbjct: 138 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 197
Query: 465 TPVAA------ALDACSGNDPFAPSEGSA----EAAPELDLFAMKPPETSVPVVTPTAST 514
TP A AL P P E ++ E P A P+ P T +A T
Sbjct: 198 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT 257
Query: 515 AP--PVPATAPSPAPAVAAAAAATTAATAAATTTT-----------TTSAATATTAP--P 559
P P P T PAP A TT A TTT TT A T P P
Sbjct: 258 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEP 317
Query: 560 ALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAF 619
A + +TP+ A + AP+ P +P + T +
Sbjct: 318 APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 377
Query: 620 AAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMA 679
PSP T PA ++ S P + A +++ SA
Sbjct: 378 KEPSPTTPKEPAPT--------------TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 423
Query: 680 PSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVS 739
P+P TP + P A TTP P +PAP +
Sbjct: 424 KEPAPTTPKEPAPTTPKKPAP--TTPKE-------------------PAPTTPKEPAPTT 462
Query: 740 MVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKV 799
P+P A + +++ + KKLT K+
Sbjct: 463 TKKPAPTTPKEPAPTTPKETAPTT----------------------PKKLT--PTTPEKL 498
Query: 800 APATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMF 859
AP T P + P P P+ P A P P P++P
Sbjct: 499 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA-PTTPKEPAPT 557
Query: 860 AQPMMRPPFGAAAVPGTQLSPSPT----PASQSPKKPPAKD 896
P P T +PT PA +PKKP K+
Sbjct: 558 TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKE 598
Score = 59.3 bits (142), Expect = 2e-08
Identities = 87/398 (21%), Positives = 126/398 (31%), Gaps = 67/398 (16%)
Query: 292 NNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLD 351
N AP+ + +P T +TP +T T+P T P + KP+ +
Sbjct: 541 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK--E 598
Query: 352 LQPDFSSGGAAAAA-APAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTP 410
L P + + PAP P G A P+ + P P+ T
Sbjct: 599 LAPTTTKEPTSTTCDKPAPTTPKGTAPT----------TPKEPAPTTPKEPAPTTPKGTA 648
Query: 411 PTTTAEIA---------------TASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAAS 455
PTT E A T STT+ A T + P
Sbjct: 649 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKK 707
Query: 456 EGAAAPATPTPVAAALDA-CSGNDPFAPSEGSAEAAPELDL------FAMKPPETSVPVV 508
P TP P + + + +P + E+ PEL P E VP
Sbjct: 708 PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTT 767
Query: 509 TPTASTAPPVPATAP---------------SPAPAVAAAAAATTAATA----AATTTTTT 549
A+T P + TA + AP + A TT T ATTT T
Sbjct: 768 KTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVT 827
Query: 550 SAATATTAPPALDIFGDL-----------FESTPEVAAAPKPDAAPSIDLFSTDAFSSPP 598
S T T P + +T E+ P+ A P ++ A + P
Sbjct: 828 STTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKP 887
Query: 599 QGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSS 636
Q + P+ T+ P TT +P K+ S+
Sbjct: 888 QKPTKAPKKP-TSTKKPKTMPRVRKPKTTPTPRKMTST 924
Score = 47.0 bits (110), Expect = 8e-05
Identities = 67/335 (20%), Positives = 108/335 (32%), Gaps = 35/335 (10%)
Query: 270 APSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVD 329
AP L T + + KP AP+ +++P T +TP K T+P
Sbjct: 664 APKELAPTTTKGPTSTTSDKP-------APTTPKETAPTTPKEPAPTTPKKPAPTTPETP 716
Query: 330 LFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLA 389
T+ + P +T +P++ + PD S+ +A P
Sbjct: 717 PPTTSEVSTPTTTKEPTT--IHKSPDESTPELSAEPTPK--------------------- 753
Query: 390 ALSSVPSEAQISDPFAPEPTPP--TTTAEIATASASASTTTTVTAVTAEVDLFGDAFAAS 447
AL + P E + P T P TTTA+ T TT T ++
Sbjct: 754 ALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 813
Query: 448 PGEAPAASEGAAAPATPTPVAAALDACS-GNDPFAPSEGSAEAAPELDLFAMKPPETSVP 506
E+ + +T T + AP + + KP ET+ P
Sbjct: 814 TTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKP 873
Query: 507 VVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGD 566
T S A P+ AP + TT + T+ P L+
Sbjct: 874 KDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSR 933
Query: 567 LFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGA 601
+ E+ + +P+ P+ L + S GA
Sbjct: 934 IAEAM--LQTTTRPNQTPNSKLVEVNPKSEDAGGA 966
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 80.9 bits (198), Expect = 5e-15
Identities = 150/666 (22%), Positives = 208/666 (31%), Gaps = 116/666 (17%)
Query: 258 GIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNST 317
G+D GD T S+ + KP N S P+ S +S T++T T
Sbjct: 132 GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPN--SDTSKETSLTVNKET 189
Query: 318 PAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGAT 377
+T +T+ +T S + S ++ + A + A P P T
Sbjct: 190 TVETKETTTTNKQTSTDGKEKTTSAKETQS----IEKTSAKDLAPTSKVLAKPTPKAETT 245
Query: 378 AWGDLLGEDSLAALSSVPSEAQISDPFAP-------------EPTPPTTTAEIATASASA 424
G L + P E + P P EP P TT + T A
Sbjct: 246 TKGPALTTPK-EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA 304
Query: 425 STTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATP------TPVAAALDACSGND 478
TTT A T + A + + PA + +AP TP TP A
Sbjct: 305 PTTTKEPAPTTPKEP-----APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 359
Query: 479 PFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTA 538
P P E + E +P T+ PTA P P T PAP A TT
Sbjct: 360 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP-APTTPKEPAPTTPKEPAPTTT 418
Query: 539 ATAAATTT-----TTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDA 593
+ TT TTT +A TT PA +AP PS A
Sbjct: 419 KEPSPTTPKEPAPTTTKSAPTTTKEPA----------PTTTKSAPTTPKEPSPTTTKEPA 468
Query: 594 FSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEP 653
++P + A P+ P+P T PA ++ EP
Sbjct: 469 PTTPKEPAPTTPKK--------------PAPTTPKEPAP---------------TTPKEP 499
Query: 654 QPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSF 713
P + + + + P+P TP + P TP+T +
Sbjct: 500 APTTTKKPAPTTPKE-------------PAPTTPKETAPTTPK-----KLTPTTPEKLA- 540
Query: 714 DPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGT 773
P+ + +AP P P PA KA + A
Sbjct: 541 -PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE--PAP 597
Query: 774 TTKKGDLQWNAGEKKLTGGANWQPK-VAPATWSAGVP--PSAPLQGAVPPTSSVPPVAGA 830
TT K E T PK AP T P P P + PT++ P +
Sbjct: 598 TTPKEPAPTTPKETAPT-----TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 652
Query: 831 PSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPK 890
P P GT P P++P P P T P+PT +PK
Sbjct: 653 CDKPAPTT-----PKGTA-PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT----TPK 702
Query: 891 KPPAKD 896
KP K+
Sbjct: 703 KPAPKE 708
Score = 73.2 bits (178), Expect = 1e-12
Identities = 87/358 (24%), Positives = 121/358 (33%), Gaps = 35/358 (9%)
Query: 298 APSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPS----SDLLDLQ 353
AP+ K +P T +TP +T T+P T P + KP+ +L
Sbjct: 500 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 559
Query: 354 PDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTT 413
P+ + AP P A T + P E + P P PT P
Sbjct: 560 PEEPTPTTPEEPAPTTPKAAAPNTP---------KEPAPTTPKEPAPTTPKEPAPTTPKE 610
Query: 414 TAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDA 473
TA T +A TT A T A + + P ++ PA TP A
Sbjct: 611 TAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT-CDKPAPTTPKGTAPTT 668
Query: 474 CSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAP-----PVPATAPSPAPA 528
P P E + +K P + P AP P T+ PAP
Sbjct: 669 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 728
Query: 529 VAAAAAATTAATAAATT-------------TTTTSAATATTAPPALDIFGDLFESTPEVA 575
A TT A TT TT+ +T TT I ESTPE++
Sbjct: 729 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 788
Query: 576 AAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKV 633
A P P A + + P A+ PE + TA + + +P TT + K+
Sbjct: 789 AEPTPKALENSPKEPGVPTTKTP--AATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 844
Score = 72.0 bits (175), Expect = 2e-12
Identities = 107/467 (22%), Positives = 151/467 (32%), Gaps = 38/467 (8%)
Query: 288 KKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKP-- 345
K+P AP+ + +P TT ++P +TP + T+ T P +T +P
Sbjct: 271 KEPTPTTIKSAPTTPKEPAPTTTKSAP-TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 329
Query: 346 ----SSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQIS 401
S+ +P ++ A P P P E + P+ +
Sbjct: 330 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 389
Query: 402 DPFAPEPTPPTTTAEIA--TASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAA 459
P AP+ PTT E A T A TTT + T +P E PA + +
Sbjct: 390 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT------------TPKE-PAPTTTKS 436
Query: 460 APATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVP 519
AP T A + P P E S E K P + P + P P
Sbjct: 437 APTTTKEPAPTTTKSA---PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 493
Query: 520 ATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPK 579
T PAP A TT A TT T+ T P L +TPE A
Sbjct: 494 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP--EKLAPTTPEKPAPTT 551
Query: 580 P-DAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGV 638
P + AP+ T P +P + T + P+P T PA
Sbjct: 552 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 611
Query: 639 IDLFGDAFG-SSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNF 697
++ EP P + + A S P+P TP P
Sbjct: 612 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 671
Query: 698 EAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPA--GQPAPVSMVP 742
A TTP + P+ G + AP +PAP + P
Sbjct: 672 PAP--TTPKEPA-----PTTPKGTAPTTLKEPAPTTPKKPAPKELAP 711
Score = 70.9 bits (172), Expect = 5e-12
Identities = 130/581 (22%), Positives = 179/581 (30%), Gaps = 111/581 (19%)
Query: 367 PAPPPP----AGGATAWGDL---LGEDSLAALSSVPSEAQISD--PFAPEPTPPTTTAEI 417
P P PP AG GD + S + V + +I+ P P P+ P +
Sbjct: 119 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 178
Query: 418 ATASASASTTTTV-----TAVTAEVDLFGDAFAASPGEAPAASEGAA---AP-----ATP 464
S + + TTV T + G S E + + +A AP A P
Sbjct: 179 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 238
Query: 465 TPVAA------ALDACSGNDPFAPSEGSA----EAAPELDLFAMKPPETSVPVVTPTAST 514
TP A AL P P E ++ E P A P+ P T +A T
Sbjct: 239 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT 298
Query: 515 AP--PVPATAPSPAPAVAAAAAATTAATAAATTTT-----------TTSAATATTAP--P 559
P P P T PAP A TT A TTT TT A T P P
Sbjct: 299 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEP 358
Query: 560 ALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAF 619
A + +TP+ A + AP+ P +P + T +
Sbjct: 359 APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 418
Query: 620 AAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMA 679
PSP T PA ++ S P + A +++ SA
Sbjct: 419 KEPSPTTPKEPAPT--------------TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 464
Query: 680 PSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVS 739
P+P TP + P A TTP P +PAP +
Sbjct: 465 KEPAPTTPKEPAPTTPKKPAP--TTPKE-------------------PAPTTPKEPAPTT 503
Query: 740 MVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKV 799
P+P A + +++ + KKLT K+
Sbjct: 504 TKKPAPTTPKEPAPTTPKETAPTT----------------------PKKLT--PTTPEKL 539
Query: 800 APATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMF 859
AP T P + P P P+ P A P P P++P
Sbjct: 540 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA-PTTPKEPAPT 598
Query: 860 AQPMMRPPFGAAAVPGTQLSPSPT----PASQSPKKPPAKD 896
P P T +PT PA +PKKP K+
Sbjct: 599 TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKE 639
Score = 59.3 bits (142), Expect = 2e-08
Identities = 87/398 (21%), Positives = 126/398 (31%), Gaps = 67/398 (16%)
Query: 292 NNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLD 351
N AP+ + +P T +TP +T T+P T P + KP+ +
Sbjct: 582 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK--E 639
Query: 352 LQPDFSSGGAAAAA-APAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTP 410
L P + + PAP P G A P+ + P P+ T
Sbjct: 640 LAPTTTKEPTSTTCDKPAPTTPKGTAPT----------TPKEPAPTTPKEPAPTTPKGTA 689
Query: 411 PTTTAEIA---------------TASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAAS 455
PTT E A T STT+ A T + P
Sbjct: 690 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKK 748
Query: 456 EGAAAPATPTPVAAALDA-CSGNDPFAPSEGSAEAAPELDL------FAMKPPETSVPVV 508
P TP P + + + +P + E+ PEL P E VP
Sbjct: 749 PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTT 808
Query: 509 TPTASTAPPVPATAP---------------SPAPAVAAAAAATTAATA----AATTTTTT 549
A+T P + TA + AP + A TT T ATTT T
Sbjct: 809 KTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVT 868
Query: 550 SAATATTAPPALDIFGDL-----------FESTPEVAAAPKPDAAPSIDLFSTDAFSSPP 598
S T T P + +T E+ P+ A P ++ A + P
Sbjct: 869 STTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKP 928
Query: 599 QGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSS 636
Q + P+ T+ P TT +P K+ S+
Sbjct: 929 QKPTKAPKKP-TSTKKPKTMPRVRKPKTTPTPRKMTST 965
Score = 47.0 bits (110), Expect = 8e-05
Identities = 67/335 (20%), Positives = 108/335 (32%), Gaps = 35/335 (10%)
Query: 270 APSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVD 329
AP L T + + KP AP+ +++P T +TP K T+P
Sbjct: 705 APKELAPTTTKGPTSTTSDKP-------APTTPKETAPTTPKEPAPTTPKKPAPTTPETP 757
Query: 330 LFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLA 389
T+ + P +T +P++ + PD S+ +A P
Sbjct: 758 PPTTSEVSTPTTTKEPTT--IHKSPDESTPELSAEPTPK--------------------- 794
Query: 390 ALSSVPSEAQISDPFAPEPTPP--TTTAEIATASASASTTTTVTAVTAEVDLFGDAFAAS 447
AL + P E + P T P TTTA+ T TT T ++
Sbjct: 795 ALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 854
Query: 448 PGEAPAASEGAAAPATPTPVAAALDACS-GNDPFAPSEGSAEAAPELDLFAMKPPETSVP 506
E+ + +T T + AP + + KP ET+ P
Sbjct: 855 TTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKP 914
Query: 507 VVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGD 566
T S A P+ AP + TT + T+ P L+
Sbjct: 915 KDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSR 974
Query: 567 LFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGA 601
+ E+ + +P+ P+ L + S GA
Sbjct: 975 IAEAM--LQTTTRPNQTPNSKLVEVNPKSEDAGGA 1007
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 80.9 bits (198), Expect = 5e-15
Identities = 150/666 (22%), Positives = 208/666 (31%), Gaps = 116/666 (17%)
Query: 258 GIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNST 317
G+D GD T S+ + KP N S P+ S +S T++T T
Sbjct: 184 GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPN--SDTSKETSLTVNKET 241
Query: 318 PAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGAT 377
+T +T+ +T S + S ++ + A + A P P T
Sbjct: 242 TVETKETTTTNKQTSTDGKEKTTSAKETQS----IEKTSAKDLAPTSKVLAKPTPKAETT 297
Query: 378 AWGDLLGEDSLAALSSVPSEAQISDPFAP-------------EPTPPTTTAEIATASASA 424
G L + P E + P P EP P TT + T A
Sbjct: 298 TKGPALTTPK-EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA 356
Query: 425 STTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATP------TPVAAALDACSGND 478
TTT A T + A + + PA + +AP TP TP A
Sbjct: 357 PTTTKEPAPTTPKEP-----APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 411
Query: 479 PFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTA 538
P P E + E +P T+ PTA P P T PAP A TT
Sbjct: 412 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP-APTTPKEPAPTTPKEPAPTTT 470
Query: 539 ATAAATTT-----TTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDA 593
+ TT TTT +A TT PA +AP PS A
Sbjct: 471 KEPSPTTPKEPAPTTTKSAPTTTKEPA----------PTTTKSAPTTPKEPSPTTTKEPA 520
Query: 594 FSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEP 653
++P + A P+ P+P T PA ++ EP
Sbjct: 521 PTTPKEPAPTTPKK--------------PAPTTPKEPAP---------------TTPKEP 551
Query: 654 QPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSF 713
P + + + + P+P TP + P TP+T +
Sbjct: 552 APTTTKKPAPTTPKE-------------PAPTTPKETAPTTPK-----KLTPTTPEKLA- 592
Query: 714 DPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGT 773
P+ + +AP P P PA KA + A
Sbjct: 593 -PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE--PAP 649
Query: 774 TTKKGDLQWNAGEKKLTGGANWQPK-VAPATWSAGVP--PSAPLQGAVPPTSSVPPVAGA 830
TT K E T PK AP T P P P + PT++ P +
Sbjct: 650 TTPKEPAPTTPKETAPT-----TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 704
Query: 831 PSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPK 890
P P GT P P++P P P T P+PT +PK
Sbjct: 705 CDKPAPTT-----PKGTA-PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT----TPK 754
Query: 891 KPPAKD 896
KP K+
Sbjct: 755 KPAPKE 760
Score = 73.2 bits (178), Expect = 1e-12
Identities = 148/680 (21%), Positives = 213/680 (31%), Gaps = 133/680 (19%)
Query: 290 PGNNEGSGAPSPLSKSSPATTVTSPN----STPAKTIDTSPPVDLFATASAAVPVSTSKP 345
P +++ + PS S++ +TT SP K I++ + + + S+S
Sbjct: 72 PPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS 131
Query: 346 SSDLLDLQPDFSSGGAAA------------------AAAPAPPPP----AGGATAWGDL- 382
SS ++ SS +AA P P PP AG GD
Sbjct: 132 SSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFK 191
Query: 383 --LGEDSLAALSSVPSEAQISD--PFAPEPTPPTTTAEIATASASASTTTTV-----TAV 433
+ S + V + +I+ P P P+ P + S + + TTV T
Sbjct: 192 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTT 251
Query: 434 TAEVDLFGDAFAASPGEAPAASEGAA---AP-----ATPTPVAA------ALDACSGNDP 479
+ G S E + + +A AP A PTP A AL P
Sbjct: 252 NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTP 311
Query: 480 FAPSEGSA----EAAPELDLFAMKPPETSVPVVTPTASTAP--PVPATAPSPAPAVAAAA 533
P E ++ E P A P+ P T +A T P P P T PAP
Sbjct: 312 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 371
Query: 534 AATTAATAAATTTT-----------TTSAATATTAP--PALDIFGDLFESTPEVAAAPKP 580
A TT A TTT TT A T P PA + +TP+ A
Sbjct: 372 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 431
Query: 581 DAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVID 640
+ AP+ P +P + T + PSP T PA
Sbjct: 432 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT------- 484
Query: 641 LFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAA 700
++ S P + A +++ SA P+P TP + P A
Sbjct: 485 -------TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 537
Query: 701 FGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSS 760
TTP P +PAP + P+P A + +++
Sbjct: 538 --TTPKE-------------------PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 576
Query: 761 LASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPP 820
+ KKLT K+AP T P + P
Sbjct: 577 PTT----------------------PKKLT--PTTPEKLAPTTPEKPAPTTPEELAPTTP 612
Query: 821 TSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSP 880
P P+ P A P P P++P P P T
Sbjct: 613 EEPTPTTPEEPAPTTPKAAAPNTPKEPA-PTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 671
Query: 881 SPT----PASQSPKKPPAKD 896
+PT PA +PKKP K+
Sbjct: 672 APTTLKEPAPTTPKKPAPKE 691
Score = 73.2 bits (178), Expect = 1e-12
Identities = 87/358 (24%), Positives = 121/358 (33%), Gaps = 35/358 (9%)
Query: 298 APSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPS----SDLLDLQ 353
AP+ K +P T +TP +T T+P T P + KP+ +L
Sbjct: 552 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 611
Query: 354 PDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTT 413
P+ + AP P A T + P E + P P PT P
Sbjct: 612 PEEPTPTTPEEPAPTTPKAAAPNTP---------KEPAPTTPKEPAPTTPKEPAPTTPKE 662
Query: 414 TAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDA 473
TA T +A TT A T A + + P ++ PA TP A
Sbjct: 663 TAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT-CDKPAPTTPKGTAPTT 720
Query: 474 CSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAP-----PVPATAPSPAPA 528
P P E + +K P + P AP P T+ PAP
Sbjct: 721 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 780
Query: 529 VAAAAAATTAATAAATT-------------TTTTSAATATTAPPALDIFGDLFESTPEVA 575
A TT A TT TT+ +T TT I ESTPE++
Sbjct: 781 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 840
Query: 576 AAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKV 633
A P P A + + P A+ PE + TA + + +P TT + K+
Sbjct: 841 AEPTPKALENSPKEPGVPTTKTP--AATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 896
Score = 72.0 bits (175), Expect = 2e-12
Identities = 107/467 (22%), Positives = 151/467 (32%), Gaps = 38/467 (8%)
Query: 288 KKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKP-- 345
K+P AP+ + +P TT ++P +TP + T+ T P +T +P
Sbjct: 323 KEPTPTTIKSAPTTPKEPAPTTTKSAP-TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 381
Query: 346 ----SSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQIS 401
S+ +P ++ A P P P E + P+ +
Sbjct: 382 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 441
Query: 402 DPFAPEPTPPTTTAEIA--TASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAA 459
P AP+ PTT E A T A TTT + T +P E PA + +
Sbjct: 442 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT------------TPKE-PAPTTTKS 488
Query: 460 APATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVP 519
AP T A + P P E S E K P + P + P P
Sbjct: 489 APTTTKEPAPTTTKSA---PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 545
Query: 520 ATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPK 579
T PAP A TT A TT T+ T P L +TPE A
Sbjct: 546 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP--EKLAPTTPEKPAPTT 603
Query: 580 P-DAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGV 638
P + AP+ T P +P + T + P+P T PA
Sbjct: 604 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 663
Query: 639 IDLFGDAFG-SSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNF 697
++ EP P + + A S P+P TP P
Sbjct: 664 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 723
Query: 698 EAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPA--GQPAPVSMVP 742
A TTP + P+ G + AP +PAP + P
Sbjct: 724 PAP--TTPKEPA-----PTTPKGTAPTTLKEPAPTTPKKPAPKELAP 763
Score = 59.3 bits (142), Expect = 2e-08
Identities = 87/398 (21%), Positives = 126/398 (31%), Gaps = 67/398 (16%)
Query: 292 NNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLD 351
N AP+ + +P T +TP +T T+P T P + KP+ +
Sbjct: 634 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK--E 691
Query: 352 LQPDFSSGGAAAAA-APAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTP 410
L P + + PAP P G A P+ + P P+ T
Sbjct: 692 LAPTTTKEPTSTTCDKPAPTTPKGTAPT----------TPKEPAPTTPKEPAPTTPKGTA 741
Query: 411 PTTTAEIA---------------TASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAAS 455
PTT E A T STT+ A T + P
Sbjct: 742 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKK 800
Query: 456 EGAAAPATPTPVAAALDA-CSGNDPFAPSEGSAEAAPELDL------FAMKPPETSVPVV 508
P TP P + + + +P + E+ PEL P E VP
Sbjct: 801 PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTT 860
Query: 509 TPTASTAPPVPATAP---------------SPAPAVAAAAAATTAATA----AATTTTTT 549
A+T P + TA + AP + A TT T ATTT T
Sbjct: 861 KTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVT 920
Query: 550 SAATATTAPPALDIFGDL-----------FESTPEVAAAPKPDAAPSIDLFSTDAFSSPP 598
S T T P + +T E+ P+ A P ++ A + P
Sbjct: 921 STTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKP 980
Query: 599 QGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSS 636
Q + P+ T+ P TT +P K+ S+
Sbjct: 981 QKPTKAPKKP-TSTKKPKTMPRVRKPKTTPTPRKMTST 1017
Score = 47.0 bits (110), Expect = 8e-05
Identities = 67/335 (20%), Positives = 108/335 (32%), Gaps = 35/335 (10%)
Query: 270 APSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVD 329
AP L T + + KP AP+ +++P T +TP K T+P
Sbjct: 757 APKELAPTTTKGPTSTTSDKP-------APTTPKETAPTTPKEPAPTTPKKPAPTTPETP 809
Query: 330 LFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLA 389
T+ + P +T +P++ + PD S+ +A P
Sbjct: 810 PPTTSEVSTPTTTKEPTT--IHKSPDESTPELSAEPTPK--------------------- 846
Query: 390 ALSSVPSEAQISDPFAPEPTPP--TTTAEIATASASASTTTTVTAVTAEVDLFGDAFAAS 447
AL + P E + P T P TTTA+ T TT T ++
Sbjct: 847 ALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 906
Query: 448 PGEAPAASEGAAAPATPTPVAAALDACS-GNDPFAPSEGSAEAAPELDLFAMKPPETSVP 506
E+ + +T T + AP + + KP ET+ P
Sbjct: 907 TTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKP 966
Query: 507 VVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGD 566
T S A P+ AP + TT + T+ P L+
Sbjct: 967 KDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSR 1026
Query: 567 LFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGA 601
+ E+ + +P+ P+ L + S GA
Sbjct: 1027 IAEAM--LQTTTRPNQTPNSKLVEVNPKSEDAGGA 1059
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 80.9 bits (198), Expect = 5e-15
Identities = 150/666 (22%), Positives = 208/666 (31%), Gaps = 116/666 (17%)
Query: 258 GIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNST 317
G+D GD T S+ + KP N S P+ S +S T++T T
Sbjct: 225 GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPN--SDTSKETSLTVNKET 282
Query: 318 PAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGAT 377
+T +T+ +T S + S ++ + A + A P P T
Sbjct: 283 TVETKETTTTNKQTSTDGKEKTTSAKETQS----IEKTSAKDLAPTSKVLAKPTPKAETT 338
Query: 378 AWGDLLGEDSLAALSSVPSEAQISDPFAP-------------EPTPPTTTAEIATASASA 424
G L + P E + P P EP P TT + T A
Sbjct: 339 TKGPALTTPK-EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA 397
Query: 425 STTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATP------TPVAAALDACSGND 478
TTT A T + A + + PA + +AP TP TP A
Sbjct: 398 PTTTKEPAPTTPKEP-----APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 452
Query: 479 PFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTA 538
P P E + E +P T+ PTA P P T PAP A TT
Sbjct: 453 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP-APTTPKEPAPTTPKEPAPTTT 511
Query: 539 ATAAATTT-----TTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDA 593
+ TT TTT +A TT PA +AP PS A
Sbjct: 512 KEPSPTTPKEPAPTTTKSAPTTTKEPA----------PTTTKSAPTTPKEPSPTTTKEPA 561
Query: 594 FSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEP 653
++P + A P+ P+P T PA ++ EP
Sbjct: 562 PTTPKEPAPTTPKK--------------PAPTTPKEPAP---------------TTPKEP 592
Query: 654 QPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSF 713
P + + + + P+P TP + P TP+T +
Sbjct: 593 APTTTKKPAPTTPKE-------------PAPTTPKETAPTTPK-----KLTPTTPEKLA- 633
Query: 714 DPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGT 773
P+ + +AP P P PA KA + A
Sbjct: 634 -PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE--PAP 690
Query: 774 TTKKGDLQWNAGEKKLTGGANWQPK-VAPATWSAGVP--PSAPLQGAVPPTSSVPPVAGA 830
TT K E T PK AP T P P P + PT++ P +
Sbjct: 691 TTPKEPAPTTPKETAPT-----TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 745
Query: 831 PSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPK 890
P P GT P P++P P P T P+PT +PK
Sbjct: 746 CDKPAPTT-----PKGTA-PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT----TPK 795
Query: 891 KPPAKD 896
KP K+
Sbjct: 796 KPAPKE 801
Score = 73.2 bits (178), Expect = 1e-12
Identities = 148/680 (21%), Positives = 213/680 (31%), Gaps = 133/680 (19%)
Query: 290 PGNNEGSGAPSPLSKSSPATTVTSPN----STPAKTIDTSPPVDLFATASAAVPVSTSKP 345
P +++ + PS S++ +TT SP K I++ + + + S+S
Sbjct: 113 PPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS 172
Query: 346 SSDLLDLQPDFSSGGAAA------------------AAAPAPPPP----AGGATAWGDL- 382
SS ++ SS +AA P P PP AG GD
Sbjct: 173 SSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFK 232
Query: 383 --LGEDSLAALSSVPSEAQISD--PFAPEPTPPTTTAEIATASASASTTTTV-----TAV 433
+ S + V + +I+ P P P+ P + S + + TTV T
Sbjct: 233 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTT 292
Query: 434 TAEVDLFGDAFAASPGEAPAASEGAA---AP-----ATPTPVAA------ALDACSGNDP 479
+ G S E + + +A AP A PTP A AL P
Sbjct: 293 NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTP 352
Query: 480 FAPSEGSA----EAAPELDLFAMKPPETSVPVVTPTASTAP--PVPATAPSPAPAVAAAA 533
P E ++ E P A P+ P T +A T P P P T PAP
Sbjct: 353 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 412
Query: 534 AATTAATAAATTTT-----------TTSAATATTAP--PALDIFGDLFESTPEVAAAPKP 580
A TT A TTT TT A T P PA + +TP+ A
Sbjct: 413 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 472
Query: 581 DAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVID 640
+ AP+ P +P + T + PSP T PA
Sbjct: 473 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT------- 525
Query: 641 LFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAA 700
++ S P + A +++ SA P+P TP + P A
Sbjct: 526 -------TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 578
Query: 701 FGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSS 760
TTP P +PAP + P+P A + +++
Sbjct: 579 --TTPKE-------------------PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 617
Query: 761 LASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPP 820
+ KKLT K+AP T P + P
Sbjct: 618 PTT----------------------PKKLT--PTTPEKLAPTTPEKPAPTTPEELAPTTP 653
Query: 821 TSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSP 880
P P+ P A P P P++P P P T
Sbjct: 654 EEPTPTTPEEPAPTTPKAAAPNTPKEPA-PTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 712
Query: 881 SPT----PASQSPKKPPAKD 896
+PT PA +PKKP K+
Sbjct: 713 APTTLKEPAPTTPKKPAPKE 732
Score = 73.2 bits (178), Expect = 1e-12
Identities = 87/358 (24%), Positives = 121/358 (33%), Gaps = 35/358 (9%)
Query: 298 APSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPS----SDLLDLQ 353
AP+ K +P T +TP +T T+P T P + KP+ +L
Sbjct: 593 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 652
Query: 354 PDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTT 413
P+ + AP P A T + P E + P P PT P
Sbjct: 653 PEEPTPTTPEEPAPTTPKAAAPNTP---------KEPAPTTPKEPAPTTPKEPAPTTPKE 703
Query: 414 TAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDA 473
TA T +A TT A T A + + P ++ PA TP A
Sbjct: 704 TAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT-CDKPAPTTPKGTAPTT 761
Query: 474 CSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAP-----PVPATAPSPAPA 528
P P E + +K P + P AP P T+ PAP
Sbjct: 762 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 821
Query: 529 VAAAAAATTAATAAATT-------------TTTTSAATATTAPPALDIFGDLFESTPEVA 575
A TT A TT TT+ +T TT I ESTPE++
Sbjct: 822 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 881
Query: 576 AAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKV 633
A P P A + + P A+ PE + TA + + +P TT + K+
Sbjct: 882 AEPTPKALENSPKEPGVPTTKTP--AATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 937
Score = 72.0 bits (175), Expect = 2e-12
Identities = 107/467 (22%), Positives = 151/467 (32%), Gaps = 38/467 (8%)
Query: 288 KKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKP-- 345
K+P AP+ + +P TT ++P +TP + T+ T P +T +P
Sbjct: 364 KEPTPTTIKSAPTTPKEPAPTTTKSAP-TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 422
Query: 346 ----SSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQIS 401
S+ +P ++ A P P P E + P+ +
Sbjct: 423 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 482
Query: 402 DPFAPEPTPPTTTAEIA--TASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAA 459
P AP+ PTT E A T A TTT + T +P E PA + +
Sbjct: 483 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT------------TPKE-PAPTTTKS 529
Query: 460 APATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVP 519
AP T A + P P E S E K P + P + P P
Sbjct: 530 APTTTKEPAPTTTKSA---PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 586
Query: 520 ATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPK 579
T PAP A TT A TT T+ T P L +TPE A
Sbjct: 587 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP--EKLAPTTPEKPAPTT 644
Query: 580 P-DAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGV 638
P + AP+ T P +P + T + P+P T PA
Sbjct: 645 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 704
Query: 639 IDLFGDAFG-SSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNF 697
++ EP P + + A S P+P TP P
Sbjct: 705 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 764
Query: 698 EAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPA--GQPAPVSMVP 742
A TTP + P+ G + AP +PAP + P
Sbjct: 765 PAP--TTPKEPA-----PTTPKGTAPTTLKEPAPTTPKKPAPKELAP 804
Score = 59.3 bits (142), Expect = 2e-08
Identities = 87/398 (21%), Positives = 126/398 (31%), Gaps = 67/398 (16%)
Query: 292 NNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLD 351
N AP+ + +P T +TP +T T+P T P + KP+ +
Sbjct: 675 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK--E 732
Query: 352 LQPDFSSGGAAAAA-APAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTP 410
L P + + PAP P G A P+ + P P+ T
Sbjct: 733 LAPTTTKEPTSTTCDKPAPTTPKGTAPT----------TPKEPAPTTPKEPAPTTPKGTA 782
Query: 411 PTTTAEIA---------------TASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAAS 455
PTT E A T STT+ A T + P
Sbjct: 783 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKK 841
Query: 456 EGAAAPATPTPVAAALDA-CSGNDPFAPSEGSAEAAPELDL------FAMKPPETSVPVV 508
P TP P + + + +P + E+ PEL P E VP
Sbjct: 842 PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTT 901
Query: 509 TPTASTAPPVPATAP---------------SPAPAVAAAAAATTAATA----AATTTTTT 549
A+T P + TA + AP + A TT T ATTT T
Sbjct: 902 KTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVT 961
Query: 550 SAATATTAPPALDIFGDL-----------FESTPEVAAAPKPDAAPSIDLFSTDAFSSPP 598
S T T P + +T E+ P+ A P ++ A + P
Sbjct: 962 STTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKP 1021
Query: 599 QGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSS 636
Q + P+ T+ P TT +P K+ S+
Sbjct: 1022 QKPTKAPKKP-TSTKKPKTMPRVRKPKTTPTPRKMTST 1058
Score = 47.0 bits (110), Expect = 8e-05
Identities = 67/335 (20%), Positives = 108/335 (32%), Gaps = 35/335 (10%)
Query: 270 APSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVD 329
AP L T + + KP AP+ +++P T +TP K T+P
Sbjct: 798 APKELAPTTTKGPTSTTSDKP-------APTTPKETAPTTPKEPAPTTPKKPAPTTPETP 850
Query: 330 LFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLA 389
T+ + P +T +P++ + PD S+ +A P
Sbjct: 851 PPTTSEVSTPTTTKEPTT--IHKSPDESTPELSAEPTPK--------------------- 887
Query: 390 ALSSVPSEAQISDPFAPEPTPP--TTTAEIATASASASTTTTVTAVTAEVDLFGDAFAAS 447
AL + P E + P T P TTTA+ T TT T ++
Sbjct: 888 ALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 947
Query: 448 PGEAPAASEGAAAPATPTPVAAALDACS-GNDPFAPSEGSAEAAPELDLFAMKPPETSVP 506
E+ + +T T + AP + + KP ET+ P
Sbjct: 948 TTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKP 1007
Query: 507 VVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGD 566
T S A P+ AP + TT + T+ P L+
Sbjct: 1008 KDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSR 1067
Query: 567 LFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGA 601
+ E+ + +P+ P+ L + S GA
Sbjct: 1068 IAEAM--LQTTTRPNQTPNSKLVEVNPKSEDAGGA 1100
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 80.9 bits (198), Expect = 5e-15
Identities = 158/710 (22%), Positives = 239/710 (33%), Gaps = 123/710 (17%)
Query: 260 DKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEG-SGAPSP-----LSKSSPATTVTS 313
+ G +P +AP Q+L + K G N SG P+P + K PATT +
Sbjct: 383 EPGALPQQPKAP--------QNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGA 434
Query: 314 PNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPA 373
P + V L S+ V P+ +L Q F GA A P
Sbjct: 435 APPQPPGALSKPMSVHLLNQGSSIVI-----PAQHMLPGQNQFLLPGAPAVQLPQQ---- 485
Query: 374 GGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPT--PPTTTAEIATASASASTTTTVT 431
+A +G LAA + I++P P + + + A + ++
Sbjct: 486 --LSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILS 543
Query: 432 AVTAEVD---LFGDAFAASPGEAPAASEGA-AAPAT---------PTPVAAALDACSGN- 477
A +V LF + + G P S+ A A PA P A L+ G
Sbjct: 544 AAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLV 603
Query: 478 DPFAPSEGSAEAAPELDL---------------FAMKPPETSVPVVTPTASTAPPVPATA 522
P P+ + EAAP L + ++ P+ P PT A P AT
Sbjct: 604 QPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATT 663
Query: 523 PSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDA 582
P P+P +A++ + T TA +L +F E + P
Sbjct: 664 PQPSPGLASSPEKIVLGQPPSAT------PTAILTQDSLQMF-----LPQERSQQPLSAE 712
Query: 583 APSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLF 642
P + + ++ S+PP P P + + +P + ASPA
Sbjct: 713 GPHLSVPASVIVSAPPPAQDPAPATPVAKGA----GLGPQAPDSQASPAP---------- 758
Query: 643 GDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQ------NNLLQPN 696
P SSS S A G S PSP P P ++ +P
Sbjct: 759 ----APQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPP 814
Query: 697 FEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSD 756
E P + + P +F L +P PA PAP + PP P + S
Sbjct: 815 SEPPLHPCPPPQAPPTL-PGIFVIQNQLGVP--PPASNPAPTAPGPPQPPLRPQ----SQ 867
Query: 757 LDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQG 816
+L S T++ + +++Q + P+ P P
Sbjct: 868 PPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLH 927
Query: 817 AVPPTSSVPP---------VAGAPSVGQPGA---GFGMPPAGT-------GMPMMPQQPV 857
VP ++ PP P++ QP A F P+G G P PQ
Sbjct: 928 LVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTST 987
Query: 858 MFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDPLADLNIKDFL 907
P+ P AA+V + +PS TP +P PA P+A + L
Sbjct: 988 SLG-PLTSP---AASVLVSGQAPSGTPT--APSHAPAPAPMAATGLPPLL 1031
Score = 37.7 bits (86), Expect = 0.049
Identities = 71/319 (22%), Positives = 102/319 (31%), Gaps = 36/319 (11%)
Query: 295 GSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQP 354
G G +P S++SPA P + P K S L A P +P
Sbjct: 744 GLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRP 803
Query: 355 DFSSGGAAAAAAPAP----PPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTP 410
+ + P PPP T G + ++ L VP A P AP P
Sbjct: 804 PSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLG----VPPPASNPAPTAPGPPQ 859
Query: 411 PTTTAEIATASASAST------TTTVTAVTAEVDLFGDAFAASPGEAPAA---SEGAAAP 461
P + ++T +AV + + A +P + S+G
Sbjct: 860 PPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKS 919
Query: 462 ATPTPVAAALDACSGNDPFAPSEGSAEAAPE---------LDLFAMKPPETSVPVVTPTA 512
TP P + + P P P L+ F P S ++ A
Sbjct: 920 PTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVP---SGIILQNKA 976
Query: 513 STAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAA------TATTAPPALDIFGD 566
AP P T+ S P + AA+ + A + T T S A AT PP L
Sbjct: 977 GGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENK 1036
Query: 567 LFEST-PEVAAAPKPDAAP 584
F S P + A + P
Sbjct: 1037 AFASNLPTLNVAKAASSGP 1055
Score = 34.3 bits (77), Expect = 0.54
Identities = 59/262 (22%), Positives = 87/262 (33%), Gaps = 52/262 (19%)
Query: 483 SEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAA 542
+E + EA ELDL + P + P P+ A AA AA A
Sbjct: 114 TEQTLEAEAELDLGPFQLP-----------TLQPADGGAGPTGAGGAAAVAAGPQALFPG 162
Query: 543 ATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGAS 602
+T AL D+ V +P ++ L P G S
Sbjct: 163 STDLLGLQGPPTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGLPNG-S 221
Query: 603 PVPESSLTADLLSVDAFAAP-----SPATTASPAKVDSSGVIDLFGDAFGSSASEPQPAS 657
P ++ T L + P +P + +V SG + S+A +P +
Sbjct: 222 PGGATAATLGLAPIQVVGQPVMALNTPTSQLLAKQVPVSGYL-------ASAAGPSEPVT 274
Query: 658 QAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSV 717
A++ S AG ++Q N AA TT + +S V
Sbjct: 275 LASAGVSPQG---AGL------------------VIQKNLSAAVATTLNGNS-------V 306
Query: 718 FDGLGDLLMPTMAPAGQPAPVS 739
F G G PT P+GQP V+
Sbjct: 307 FGGAGAASAPTGTPSGQPLAVA 328
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 79.7 bits (195), Expect = 1e-14
Identities = 122/485 (25%), Positives = 187/485 (38%), Gaps = 64/485 (13%)
Query: 265 PDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDT 324
PD T +P+S + +T +PG+ + P + + T+ +S+P T T
Sbjct: 1701 PDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTT 1760
Query: 325 SPPVDLFATASAAVPVST---SKPSSDLLDLQPD-FSSGGAAAAAAPAPP---------P 371
P TAS+ P ST S P S L PD ++ G A+ P
Sbjct: 1761 LSPGS--TTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLS 1818
Query: 372 PAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTA---EIATASASASTTT 428
PAG T G+ S PS P PPTTT+ E++T S + ++T
Sbjct: 1819 PAGSTTRQGE------STTFQSWPSSKDTM------PAPPTTTSAFVELSTTSHGSPSST 1866
Query: 429 TVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDA-CSGNDPFAPSEGSA 487
T +A G S S A TP+P + + + S GS
Sbjct: 1867 PTTHFSASSTTLG----RSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGST 1922
Query: 488 EAA--PELDLFAMKPPE--TSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAA 543
+ PE + + E TS T T S +PP +A P ++ +TA T
Sbjct: 1923 QTMHFPESSTASGRSEESRTSHSSTTHTIS-SPPSTTSALVEEPTSYHSSPGSTATTHFP 1981
Query: 544 TTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASP 603
++TT+ + +TA + ++T + + + + +T SS +
Sbjct: 1982 DSSTTSGRSEESTASHSSQ------DATGTIVLPARSTTSVLLGESTTSPISSGSMETTA 2035
Query: 604 VPESSLTADL--LSVDAFAAP-SPATTASPAKVDSSGVIDLFGDAFGSSASEPQPAS--- 657
+P S+ T L S ++P SPATT SPA SSGV + S+ S +P S
Sbjct: 2036 LPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSE------ESTTSHSRPGSTHT 2089
Query: 658 QAASSSSASADLLAGFGGSFMAPSPSPVT--PAQNNLLQPNFEAAFGTTPSTSSSSSFDP 715
A S+ + L S +P + T PA P+ E +T S SS S D
Sbjct: 2090 TAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQE----STTSHSSPGSTDT 2145
Query: 716 SVFDG 720
++ G
Sbjct: 2146 ALSPG 2150
Score = 79.0 bits (193), Expect = 2e-14
Identities = 122/485 (25%), Positives = 189/485 (38%), Gaps = 64/485 (13%)
Query: 265 PDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDT 324
PD T +P+S + +T +PG+ + P + + T+ +S+P T T
Sbjct: 3258 PDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTT 3317
Query: 325 SPPVDLFATASAAVPVST---SKPSSDLLDLQPD-FSSGGAAAAAAPAPP---------P 371
P TAS+ P ST S P S L PD ++ G A+ P
Sbjct: 3318 LSPGS--TTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLS 3375
Query: 372 PAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTA---EIATASASASTTT 428
PAG T G+ S P+ + P PPTTT+ E++T S + ++T
Sbjct: 3376 PAGSTTRQGE------STTFQSWPNSKDTT------PAPPTTTSAFVELSTTSHGSPSST 3423
Query: 429 TVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDA-CSGNDPFAPSEGSA 487
T +A G S S A TP+P + + + S GS
Sbjct: 3424 PTTHFSASSTTLG----RSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGST 3479
Query: 488 EAA--PELDLFAMKPPE--TSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAA 543
+ PE D + + E TS T T S+AP +A P ++ +TA T
Sbjct: 3480 QTMHFPESDTTSGRGEESTTSHSSTTHTISSAPST-TSALVEEPTSYHSSPGSTATTHFP 3538
Query: 544 TTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASP 603
++TT+ + +TA + ++T + + + + +T SS +
Sbjct: 3539 DSSTTSGRSEESTASHSSQ------DATGTIVLPARSTTSVLLGESTTSPISSGSMETTA 3592
Query: 604 VPESSLTADL--LSVDAFAAP-SPATTASPAKVDSSGVIDLFGDAFGSSASEPQPAS--- 657
+P S+ T L S ++P SPATT SPA SSGV + S+ S +P S
Sbjct: 3593 LPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSE------ESTTSHSRPGSTHT 3646
Query: 658 QAASSSSASADLLAGFGGSFMAPSPSPVT--PAQNNLLQPNFEAAFGTTPSTSSSSSFDP 715
A S+ + L S +P + T PA + E +T S SSS S D
Sbjct: 3647 TAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQE----STTSHSSSGSTDT 3702
Query: 716 SVFDG 720
++ G
Sbjct: 3703 ALSPG 3707
Score = 77.0 bits (188), Expect = 7e-14
Identities = 158/685 (23%), Positives = 259/685 (37%), Gaps = 105/685 (15%)
Query: 265 PDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDT 324
PD T +P+S + +T +PG+ + PS + + T+ +S+P T T
Sbjct: 4341 PDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTT 4400
Query: 325 SPPVDLFATASAAVPVST---SKPSSDLLDLQPD-FSSGGAAAAAAPAPP---------P 371
P TAS+ P ST S P S L PD ++ G A+ P
Sbjct: 4401 LSPGS--TTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLS 4458
Query: 372 PAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTA---EIATASASASTTT 428
PAG T G+ S P+ + P PPTTT+ E++T S + ++T
Sbjct: 4459 PAGSTTRQGE------STTFQSWPNSKDTT------PAPPTTTSAFVELSTTSHGSPSST 4506
Query: 429 TVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDA-CSGNDPFAPSEGSA 487
T +A G S S A TP+P + + + S GS
Sbjct: 4507 PTTHFSASSTTLG----RSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGST 4562
Query: 488 EAA--PELDLFAMKPPE--TSVPVVTPTASTAPPVPA------TAPSPAPAVAAA----- 532
+ PE + + + E TS T T S+AP + T+ +P A
Sbjct: 4563 QTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPD 4622
Query: 533 AAATTAATAAATTTTTTSAATATTAPPALDIFGDLF-ESTP--------EVAAAPKPDAA 583
++ T+ + +T + ++ AT T PA L EST E A P
Sbjct: 4623 SSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT 4682
Query: 584 PSIDLFSTDAFSSPPQGASPVPESSLTADLL-----SVDAFAAP-SPATTASPAKVDSSG 637
P + ST SSP ++P S ++ L S ++P + ATT SPA+ +SG
Sbjct: 4683 PGLSEKSTTFHSSP--SSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSG 4740
Query: 638 VID---LFGDAFGSSASEPQPASQAAS--------SSSASADLLAG--FGGSFMAPSPSP 684
+++ + + GS+ + P S AS S S++ ++ S + P+
Sbjct: 4741 LVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTS 4800
Query: 685 VTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPT-MAPAGQPAPVSMVPP 743
+ ++ +F + TT S S+ S D G +P +G+ A +
Sbjct: 4801 YHSSPGSIATTHFPES-STTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYI 4859
Query: 744 SPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPAT 803
SP ++++LAS G+S +T + +++ + P ++
Sbjct: 4860 SP---------GSMETTLASTATTPGLSAKST----ILYSSSR---SPDQTLSPASMTSS 4903
Query: 804 WSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQ--PVMFAQ 861
+G P S Q T++ P + Q F P T + P FAQ
Sbjct: 4904 SISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQ 4963
Query: 862 PMMRPPFGAAAVPGTQLSPSPTPAS 886
P + PG+ LS + +PAS
Sbjct: 4964 EFTTP----HSQPGSALS-TVSPAS 4983
Score = 68.9 bits (167), Expect = 2e-11
Identities = 118/487 (24%), Positives = 174/487 (35%), Gaps = 96/487 (19%)
Query: 265 PDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDT 324
PD T P+S+ + +T +PG+ + P + + T+ +S+P T T
Sbjct: 646 PDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTT 705
Query: 325 SPPVDLFATASAAVPVST---SKPSSDLLDLQPD-FSSGGAAAAAAPAPP---------P 371
P TAS+ P T S+P S L PD ++ G A+ P
Sbjct: 706 LSPGS--TTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLS 763
Query: 372 PAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTA---EIATASASASTTT 428
PAG T G+ S PS P PPTTT+ E +T S + ++
Sbjct: 764 PAGSTTRQGE------STTFHSWPSSKD------TRPAPPTTTSAFVEPSTTSHGSPSSI 811
Query: 429 TVTAVTAEVDLFG-----DAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPS 483
T ++A G + +SPG +T T D SG
Sbjct: 812 PTTHISARSTTSGLVEESTTYHSSPG------------STQTMHFPESDTTSGRG----E 855
Query: 484 EGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAA- 542
E + + + P TS V PT+ + P +TA + P + + + +TA+
Sbjct: 856 ESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSP-GSTATTHFPDSSTTSGRSEESTASH 914
Query: 543 ----ATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPP 598
AT T A + T+ + + E A P P + ST SSP
Sbjct: 915 SSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSP- 973
Query: 599 QGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPAS- 657
SPATT SPA SSGV + S+ S +P S
Sbjct: 974 -----------------------RSPATTLSPASTTSSGVSE------ESTTSRSRPGST 1004
Query: 658 --QAASSSSASADLLAGFGGSFMAPSPSPVT--PAQNNLLQPNFEAAFGTTPSTSSSSSF 713
A S+ + L S +P + T PA P+ E +T S SSS S
Sbjct: 1005 HTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQE----STTSHSSSGST 1060
Query: 714 DPSVFDG 720
D ++ G
Sbjct: 1061 DTALSPG 1067
Score = 65.9 bits (159), Expect = 2e-10
Identities = 130/610 (21%), Positives = 210/610 (34%), Gaps = 84/610 (13%)
Query: 296 SGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPD 355
S SP + SPA+T +S S + T + P +T + A P ST+ P
Sbjct: 3611 SSPRSPATTLSPASTTSSGVSEESTTSHSRPG----STHTTAFPDSTTTPGLSRHSTTSH 3666
Query: 356 FSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTA 415
S G PA +G + E + + SS ++ +S P +TTA
Sbjct: 3667 SSPGSTDTTLLPASTTTSGSSQ-------ESTTSHSSSGSTDTALS--------PGSTTA 3711
Query: 416 EIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACS 475
+ STT + + LF D+ +S G A++ ++ +P L S
Sbjct: 3712 ---LSFGQESTTFHSSPGSTHTTLFPDSTTSS-GIVEASTRVHSSTGSPR---TTLSPAS 3764
Query: 476 GNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPAT----APSPAPAVAA 531
P E +A F P T P+ +TAP +T +P P
Sbjct: 3765 STSPGLQGESTA--------FQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF 3816
Query: 532 AAAATTAATAAATTT---------TTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDA 582
A++TT+ + +T TT S+A +TT+ + + E+ P
Sbjct: 3817 PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTT 3876
Query: 583 APSIDLFSTDAFSSPPQGA---SPVPESSLTADLLSVDAFAAP-------SPATTASPAK 632
P + ST +SSP SP +SL S + + P SPA+T +P
Sbjct: 3877 TPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL 3936
Query: 633 VDSSGVI----------DLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSP 682
+ S + +F + +S +P + + +S L +
Sbjct: 3937 SEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEE 3996
Query: 683 SPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMP----TMAPAGQPAPV 738
S P Q A T S++F PS G L P T G+ P
Sbjct: 3997 STAFPGSPASTQTGLPATLTTADLGEESTTF-PSSSGSTGTKLSPARSTTSGLVGESTPS 4055
Query: 739 SMVPPS------PAMAASKALGSDLDSSLAS-LVGNLGISGTTTKKGDLQWNAGEKKLTG 791
+ P S P + +L + S + +S TT + +
Sbjct: 4056 RLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQP 4115
Query: 792 GANWQPKVAPATWSAGV----PPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGT 847
G+ +T ++G+ S QG+ T S P A S+GQ F P T
Sbjct: 4116 GSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLS-PGSTTASSLGQQSTTFHSSPGDT 4174
Query: 848 GMPMMPQQPV 857
++P +
Sbjct: 4175 ETTLLPDDTI 4184
Score = 65.5 bits (158), Expect = 2e-10
Identities = 137/659 (20%), Positives = 223/659 (33%), Gaps = 74/659 (11%)
Query: 270 APSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTS------------PNST 317
+P+S L L T + + S + S + SPA + TS P+ST
Sbjct: 2446 SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSST 2505
Query: 318 PAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGAT 377
T+ SP + S S P + L SSG + ++ P + T
Sbjct: 2506 ETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTT-SSGVSEESSTSHSQPGSTHTT 2564
Query: 378 AWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTA---EIATASASASTTTTVTAVT 434
A+ D L+ S+ + S P TT+ E T+ +S +T T +
Sbjct: 2565 AFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPG 2624
Query: 435 AEVDL-FGD---AFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAA 490
+ L FG F +SPG + ++ A+ S P ++ +
Sbjct: 2625 STTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTS 2684
Query: 491 PELD----LFAMKPPETSVPVVTPTASTAPPVPAT----APSPAPAVAAAAAATTAATAA 542
P L F P T P+ +TAP +T +P P A++TT+ +
Sbjct: 2685 PGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSE 2744
Query: 543 ATTT---------TTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDA 593
+T TT S+A +TT+ + + E+ P P + ST
Sbjct: 2745 KSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF 2804
Query: 594 FSSPPQGA---SPVPESSLTADLLSVDAFAAP-------SPATTASPAKVDSSGVI---- 639
+SSP SP +SL S + + P SPA+T +P + S +
Sbjct: 2805 YSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSS 2864
Query: 640 ------DLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLL 693
+F + +S +P + + +S L + S P
Sbjct: 2865 PGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAST 2924
Query: 694 QPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMP----TMAPAGQPAPVSMVPPS----- 744
Q A T S++F PS G L P T G+ P + P S
Sbjct: 2925 QTGLPATLTTADLGEESTTF-PSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTT 2983
Query: 745 -PAMAASKALGSDLDSSLAS-LVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPA 802
P + +L + S + +S TT + + G+ +
Sbjct: 2984 LPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDS 3043
Query: 803 TWSAGV----PPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPV 857
T ++G+ S QG+ T S P A S+GQ F P T ++P +
Sbjct: 3044 TTTSGLSQEPTASHSSQGSTEATLS-PGSTTASSLGQQSTTFHSSPGDTETTLLPDDTI 3101
Score = 63.9 bits (154), Expect = 6e-10
Identities = 110/502 (21%), Positives = 177/502 (35%), Gaps = 98/502 (19%)
Query: 296 SGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPD 355
S SP + SPA+T +S S + T + P +T + A P ST+ P
Sbjct: 2054 SSPRSPATTLSPASTTSSGVSEESTTSHSRPG----STHTTAFPDSTTTPGLSRHSTTSH 2109
Query: 356 FSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTA 415
S G PA +G PS+ + +P T +
Sbjct: 2110 SSPGSTDTTLLPASTTTSG--------------------PSQESTTSHSSPGSTDTALSP 2149
Query: 416 EIATASASASTTTTVTAV--TAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDA 473
TA + +TT + + LF D+ +S G A++ ++ +P L
Sbjct: 2150 GSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSS-GIVEASTRVHSSTGSPR---TTLSP 2205
Query: 474 CSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPAT----APSPAPAV 529
S P E +A F P T P+ +TAP +T +P P
Sbjct: 2206 ASSTSPGLQGESTA--------FQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT 2257
Query: 530 AAAAAATTAATAAATTT---------TTTSAATATTAPPALDIFGDLFESTPEVAAAPKP 580
A++TT+ + +T TT S+A +TT+ + + E+ P
Sbjct: 2258 HFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGS 2317
Query: 581 DAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVID 640
P + ST +SSP SP TT SPA + S GV
Sbjct: 2318 TTTPGLSEASTTFYSSP------------------------RSPTTTLSPASMTSLGV-- 2351
Query: 641 LFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPS-------PVTPAQNNLL 693
G+ +S S+P S +S + L+ + + SP P TP + +
Sbjct: 2352 --GEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTS--V 2407
Query: 694 QPNFEAAFGTTPSTSSSSSF-DPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKA 752
+ F + P+++ ++ F + S GL + + A G PA P+ A
Sbjct: 2408 RGEEPTTFHSRPASTHTTLFTEDSTTSGLTE---ESTAFPGSPASTQTGLPATLTTA--- 2461
Query: 753 LGSDLDSSLASLVGNLGISGTT 774
DL + + G +GTT
Sbjct: 2462 ---DLGEESTTFPSSSGSTGTT 2480
Score = 63.2 bits (152), Expect = 1e-09
Identities = 131/611 (21%), Positives = 208/611 (34%), Gaps = 86/611 (14%)
Query: 296 SGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPD 355
S SP + SPA+T +S S + T + P +T + A P ST+ P
Sbjct: 971 SSPRSPATTLSPASTTSSGVSEESTTSRSRPG----STHTTAFPDSTTTPGLSRHSTTSH 1026
Query: 356 FSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTA 415
S G PA +G + E + + SS ++ +S P +TTA
Sbjct: 1027 SSPGSTDTTLLPASTTTSGPSQ-------ESTTSHSSSGSTDTALS--------PGSTTA 1071
Query: 416 EIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACS 475
+ STT + LF D+ +S G A++ ++ +P L S
Sbjct: 1072 ---LSFGQESTTFHSNPGSTHTTLFPDSTTSS-GIVEASTRVHSSTGSPR---TTLSPAS 1124
Query: 476 GNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPAT----APSPAPAVAA 531
P E +A F P T P+ +TAP +T +P P
Sbjct: 1125 STSPGLQGESTA--------FQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF 1176
Query: 532 AAAATTAATAAATTT---------TTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDA 582
A++TT+ + +T TT S+A +TT+ + + E+ P
Sbjct: 1177 PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTT 1236
Query: 583 APSIDLFSTDAFSSPPQGA---SPVPESSLTADLLSVDAFAAP-------SPATTASPAK 632
P + ST +SSP SP +SL S + + P SPA+T +P
Sbjct: 1237 TPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL 1296
Query: 633 VDSSGVI----------DLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSP 682
+ S + +F + +S +P + + +S L +
Sbjct: 1297 SEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEE 1356
Query: 683 SPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMP----TMAPAGQPAP- 737
S P Q A T S++F PS G L P T G+ P
Sbjct: 1357 STAFPGSPASTQTGLPATLTTADLGEESTTF-PSSSGSTGTKLSPARSTTSGLVGESTPS 1415
Query: 738 --------VSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKL 789
+ +P SP + + +S S L TTT G + ++
Sbjct: 1416 RLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS-PATTTSSGVSEESSTSHSQ 1474
Query: 790 TGGAN---WQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAG 846
G + + + S S QG+ T S P A S+GQ F P
Sbjct: 1475 PGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLS-PGSTTASSLGQQSTTFHSSPGD 1533
Query: 847 TGMPMMPQQPV 857
T ++P +
Sbjct: 1534 TETTLLPDDTI 1544
Score = 63.2 bits (152), Expect = 1e-09
Identities = 124/538 (23%), Positives = 195/538 (36%), Gaps = 100/538 (18%)
Query: 278 LEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAA 337
L + T+ PG+ E + P + S T+ +S PA T T D +T S
Sbjct: 3936 LSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTED--STTSGL 3993
Query: 338 VPVSTSKPSS---------------DLLDLQPDF--SSGGAAAAAAPAPPPPAGGATAWG 380
ST+ P S DL + F SSG +PA +G
Sbjct: 3994 TEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG------ 4047
Query: 381 DLLGEDSLAALS-------------SVPSEAQISDPFAPEPTPPTTTAEIATASASA--- 424
L+GE + + LS + PS ++ S F P P T AT ++S
Sbjct: 4048 -LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSE 4106
Query: 425 -STTTTVTAVTAEVDLFGDAFAASP-GEAPAASEGA--AAPATPTP---VAAALDACSGN 477
S+T+ + F D+ S + P S + + AT +P A++L S
Sbjct: 4107 ESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTT 4166
Query: 478 DPFAPSEGSAEAAPELDLFAMKPPETSVP----------VVTPTASTA------------ 515
+P + P+ D E S P +TP +ST+
Sbjct: 4167 FHSSPGDTETTLLPD-DTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQS 4225
Query: 516 -PPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEV 574
P T PSP A +T + ++T TT + ++T + + S
Sbjct: 4226 WPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGAT 4285
Query: 575 AAAPKPDAAPSIDLF---STDAFSSPPQGASPVPESSLTADL--LSVDAFAAP-SPATTA 628
A P + + L +T SS + +P S+ TA L S +++P SP TT
Sbjct: 4286 GTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTL 4345
Query: 629 SPAKVDSSGVID-----------LFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSF 677
SPA SSGV + + AF SS + P + ++ +S S+ G +
Sbjct: 4346 SPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSP-------GSTD 4398
Query: 678 MAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQP 735
SP T + F ++ G+T +T D + GL + P + G P
Sbjct: 4399 TTLSPGSTTASSLGPESTTFHSSPGSTETTLLP---DNTTASGLLEASTPVHSSTGSP 4453
Score = 62.0 bits (149), Expect = 2e-09
Identities = 125/637 (19%), Positives = 225/637 (35%), Gaps = 69/637 (10%)
Query: 265 PDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDT 324
PD T +P++ + ++ +PG+ + P + S + T+ +S+ T T
Sbjct: 1450 PDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEAT 1509
Query: 325 SPPVDLFATASAAVPVST---SKPSSDLLDLQPDFS-SGGAAAAAAPAPPP--------- 371
P TAS+ ST S P L PD + + G A+ P
Sbjct: 1510 LSPGS--TTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT 1567
Query: 372 PAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTA---EIATASASASTTT 428
PA +A L E+S S PS + + P+PP TTA E++T S ++T
Sbjct: 1568 PASSTSAG---LQEES-TTFQSWPSSSDTT------PSPPGTTAAPVEVSTTYHSRPSST 1617
Query: 429 TVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAP-SEGSA 487
T +A G + ++ + + G A P +A G +P S GS
Sbjct: 1618 PTTHFSASSTTLGRSEESTTVHSSPGATGTAL----FPTRSATSVLVGEPTTSPISSGST 1673
Query: 488 EA------------------------APELDLFAMKPPETSVPVVTPTASTAPPVPATAP 523
E +P+ L + V + T+ + P T
Sbjct: 1674 ETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTA 1733
Query: 524 SPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTP---EVAAAPKP 580
P + + A+ ++ +T T+ + +T +L F S+P E P
Sbjct: 1734 FPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDN 1793
Query: 581 DAAPSIDLFSTDAFSSPPQGASPV-PESSLTADLLSVDAFAAPSPATTASPAKVDSSGVI 639
A + ST SS + + P S T S + PS T +S +
Sbjct: 1794 TTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFV 1853
Query: 640 DLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGS--FMAPSPSPVTPAQNNLLQPNF 697
+L + GS +S P A+S++ ++ S A +PSP + L++ +
Sbjct: 1854 ELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEES- 1912
Query: 698 EAAFGTTPSTSSSSSF-DPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSD 756
A+ ++P ++ + F + S G + + PPS A + S
Sbjct: 1913 -TAYHSSPGSTQTMHFPESSTASGRSE---ESRTSHSSTTHTISSPPSTTSALVEEPTSY 1968
Query: 757 LDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQG 816
S ++ + S TT+ + + + + G P + + G ++P+
Sbjct: 1969 HSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISS 2028
Query: 817 AVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMP 853
T+++P P + + F P + P
Sbjct: 2029 GSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSP 2065
Score = 62.0 bits (149), Expect = 2e-09
Identities = 125/520 (24%), Positives = 188/520 (36%), Gaps = 76/520 (14%)
Query: 266 DLTQAPSSLMETLEQHLNTLEGKKPGNNE---GSGAPSPLSKSSPATTV-TSPNSTPAKT 321
D T P+S + +T PG+ + G+ + LS +TT +SP ST
Sbjct: 2116 DTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTL 2175
Query: 322 IDTSPPVDLFATASAAVPVSTSKP-------SSDLLDLQPD---FSSGGAAAAAAPAPP- 370
S AS V ST P SS LQ + F + A+ P+PP
Sbjct: 2176 FPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPS 2235
Query: 371 ---PPAGGATAWGDLLGE---DSLAALSSVPSEAQISDPFAPEPTPPTTT---AEIATAS 421
P +T + G A S+ ++ S F P TT A T+
Sbjct: 2236 TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG 2295
Query: 422 ASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDAC------- 474
STT+ ++ + E+ + +PG + A++ ++P +PT +
Sbjct: 2296 RGESTTSRISPGSTEITTLPGS-TTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEE 2354
Query: 475 ---------SGNDPFAPSEGSAEAAPE--LDLFAMKP--PETSVPVVTPTASTAPPVPAT 521
S + +P+ + E +++ P ET+V TPT S P T
Sbjct: 2355 STTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTT 2414
Query: 522 ---APSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFEST---PEVA 575
P+ +TT+ +T S A+ T PA DL E + P +
Sbjct: 2415 FHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS 2474
Query: 576 AAPKPDAAPSIDLFSTDAFSSPPQGASP-------VPESSLTADL--LSVDAFAAP-SPA 625
+ +P+ S S P SP +P S T L S + +P SP
Sbjct: 2475 GSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPD 2534
Query: 626 TTASPAKVDSSGVIDLFGDAFGSSASEPQPAS---QAASSSSASADLLAGFGGSFMAPSP 682
T SPA SSGV + SS S QP S A S+ + L S +P
Sbjct: 2535 ATLSPATTTSSGVSE------ESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGS 2588
Query: 683 SPVT--PAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDG 720
+ T PA P+ E +T S SS S D ++ G
Sbjct: 2589 TDTTLLPASTTTSGPSQE----STTSHSSPGSTDTALSPG 2624
Score = 61.6 bits (148), Expect = 3e-09
Identities = 130/609 (21%), Positives = 219/609 (35%), Gaps = 108/609 (17%)
Query: 271 PSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTS---------PNSTPAKT 321
P+S TL +T G + G+P+ PAT T+ P+S+ +
Sbjct: 1336 PASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTG 1395
Query: 322 IDTSPPVDLF------ATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAP-APPPPAG 374
SP +T S P ST + P S +P +P
Sbjct: 1396 TKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS 1455
Query: 375 GATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIA-----TASASASTTTT 429
AT + E+S + S S + P TTT++++ + S+ ST T
Sbjct: 1456 PATTTSSGVSEESSTSHSQPGSTHTTAFP------DSTTTSDLSQEPTTSHSSQGSTEAT 1509
Query: 430 VTAVTAEVDLFGD---AFAASPGEAPAA-------SEGAAAPATPTPVAAALDACSGNDP 479
++ + G F +SPG+ + G +TPT + S +
Sbjct: 1510 LSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTG----SLHTT 1565
Query: 480 FAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATA-----PSPAPAVAAAAA 534
P+ ++ E P +S +P +TA PV + PS P +A+
Sbjct: 1566 LTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSAS 1625
Query: 535 ATTAATAAATTTTTTS-AATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDA 593
+TT + +TT +S AT T P +T + P +T
Sbjct: 1626 STTLGRSEESTTVHSSPGATGTALFPTR-------SATSVLVGEP-----------TTSP 1667
Query: 594 FSSPPQGASPVPESSLTADL--LSVDAFAAP-SPATTASPAKVDSSGVIDLFGDAFGSSA 650
SS + +P S+ TA L S +++P SP TT SPA SSGV + S+
Sbjct: 1668 ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSE------ESTT 1721
Query: 651 SEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSS 710
S +P S ++ F GS P S + A ++ P +P ++++
Sbjct: 1722 SHSRPGSTHTTA----------FPGSTTMPGVSQESTASHS--SPG-STDTTLSPGSTTA 1768
Query: 711 SSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGI 770
SS P T + +++P + + + + SS S L
Sbjct: 1769 SSLGPE---------STTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSP 1819
Query: 771 SGTTTKKGD----LQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPP 826
+G+TT++G+ W + + + P T SA V S G+ T +
Sbjct: 1820 AGSTTRQGESTTFQSWPSSKDTM--------PAPPTTTSAFVELSTTSHGSPSSTPTTHF 1871
Query: 827 VAGAPSVGQ 835
A + ++G+
Sbjct: 1872 SASSTTLGR 1880
Score = 61.6 bits (148), Expect = 3e-09
Identities = 122/630 (19%), Positives = 231/630 (36%), Gaps = 67/630 (10%)
Query: 265 PDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDT 324
PD T +P++ + ++ +PG+ + P + S + T+ +S+ T T
Sbjct: 4090 PDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEAT 4149
Query: 325 SPPVDLFATASAAVPVST---SKPSSDLLDLQPDFS-SGGAAAAAAPAPPPPAG------ 374
P TAS+ ST S P L PD + + G A+ P
Sbjct: 4150 LSPGS--TTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT 4207
Query: 375 GATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTA---EIATASASASTTTTVT 431
A++ L E+S S PS + + P+PP+TTA E++T S ++T T
Sbjct: 4208 PASSTSTGLQEES-TTFQSWPSSSDTT------PSPPSTTAVPVEVSTTYHSRPSSTPTT 4260
Query: 432 AVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAP-SEGSAEA- 489
+A G + ++ + + G A P +A G +P S GS E
Sbjct: 4261 HFSASSTTLGRSEESTTVHSSPGATGTAL----FPTRSATSVLVGEPTTSPISSGSTETT 4316
Query: 490 -----------------------APELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPA 526
+P+ L + V + T+ + P T P+
Sbjct: 4317 ALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPS 4376
Query: 527 PAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTP---EVAAAPKPDAA 583
+ + A+ ++ +T T+ + +T +L F S+P E P A
Sbjct: 4377 STTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTA 4436
Query: 584 PSIDLFSTDAFS---SPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVID 640
+ ST S SP SP ++ + + ++ T A P +S ++
Sbjct: 4437 SGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPP--TTTSAFVE 4494
Query: 641 LFGDAFGSSASEPQPASQAASSSSASADLLAGFGGS--FMAPSPSPVTPAQNNLLQPNFE 698
L + GS +S P A+S++ ++ S A +PSP + L++ +
Sbjct: 4495 LSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEES-- 4552
Query: 699 AAFGTTPSTSSSSSF-DPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDL 757
+ ++P ++ + F + + G G+ T + + +S PS A + S
Sbjct: 4553 TTYHSSPGSTQTMHFPESNTTSGRGE--ESTTSHSSTTHTISSA-PSTTSALVEEPTSYH 4609
Query: 758 DSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGA 817
S ++ + S TT+ + + + + G P + + G ++P+
Sbjct: 4610 SSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSG 4669
Query: 818 VPPTSSVPPVAGAPSVGQPGAGFGMPPAGT 847
T+++P P + + F P+ T
Sbjct: 4670 SMETTALPGSTTTPGLSEKSTTFHSSPSST 4699
Score = 58.9 bits (141), Expect = 2e-08
Identities = 125/639 (19%), Positives = 228/639 (35%), Gaps = 73/639 (11%)
Query: 265 PDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDT 324
PD T +P++ + ++ +PG+ + P + S + T+ +S+ T T
Sbjct: 3007 PDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEAT 3066
Query: 325 SPPVDLFATASAAVPVST---SKPSSDLLDLQPDFS-SGGAAAAAAPAPPP--------- 371
P TAS+ ST S P L PD + + G A+ P
Sbjct: 3067 LSPGS--TTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT 3124
Query: 372 PAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTA---EIATASASASTTT 428
PA +A L E+S S PS + + P+PP TTA E++T S ++T
Sbjct: 3125 PASSTSAG---LQEES-TTFQSWPSSSDTT------PSPPGTTAAPVEVSTTYHSRPSST 3174
Query: 429 TVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAP-SEGSA 487
T +A G + ++ + + G A P +A G +P S GS
Sbjct: 3175 PTTHFSASSTTLGRSEESTTVHSSPGATGTAL----FPTRSATSVLVGEPTTSPISSGST 3230
Query: 488 EA------------------------APELDLFAMKPPETSVPVVTPTASTAPPVPATAP 523
E +P+ L + V + T+ + P T
Sbjct: 3231 ETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTA 3290
Query: 524 SPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTP---EVAAAPKP 580
P + + A+ ++ +T T+ + +T +L F S P E P
Sbjct: 3291 FPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDN 3350
Query: 581 DAAPSIDLFSTDAFS---SPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSG 637
A + ST S SP SP ++ + + ++ T A P +S
Sbjct: 3351 TTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPP--TTTSA 3408
Query: 638 VIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGS--FMAPSPSPVTPAQNNLLQP 695
++L + GS +S P A+S++ ++ S A +PSP + L++
Sbjct: 3409 FVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEE 3468
Query: 696 NFEAAFGTTPSTSSSSSFDPS-VFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALG 754
+ + ++P ++ + F S G G+ T + + +S PS A +
Sbjct: 3469 S--TTYHSSPGSTQTMHFPESDTTSGRGE--ESTTSHSSTTHTISSA-PSTTSALVEEPT 3523
Query: 755 SDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPL 814
S S ++ + S TT+ + + + + G P + + G ++P+
Sbjct: 3524 SYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPI 3583
Query: 815 QGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMP 853
T+++P P + + F P + P
Sbjct: 3584 SSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSP 3622
Score = 56.2 bits (134), Expect = 1e-07
Identities = 124/573 (21%), Positives = 207/573 (36%), Gaps = 74/573 (12%)
Query: 265 PDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDT 324
PD T +P+ + +T +PG P + + T+ +S P T T
Sbjct: 290 PDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTT 349
Query: 325 SPPVDLFATASAAVPVSTSKPSS----DLLDLQPDFSSGGAAAAAAP---APPPPAGGAT 377
P T S+ P ST+ SS L + ++ G A+ P + P +
Sbjct: 350 LSPGT--TTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLS 407
Query: 378 AWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTA---EIATASASASTTTTVTAVT 434
E S PS S P P TT+ +++T S+ ++T T +
Sbjct: 408 PSSSTTHEGEPTTFQSWPSSKDTS------PAPSGTTSAFVKLSTTYHSSPSSTPTTHFS 461
Query: 435 AEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDA-CSGNDPFAPSEGSAEAAPEL 493
A G S P S A TP P +A + + S GS +
Sbjct: 462 ASSTTLGH----SEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQ----- 512
Query: 494 DLFAMKPPETSVPV-VTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAA 552
M PE+S + ++T S P+ AA A T+ ++ +T TT
Sbjct: 513 ---TMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRD 569
Query: 553 TATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGAS----PVPESS 608
++T + + + S+P+ A A + + D+ SP S +P S+
Sbjct: 570 SSTISGRSEE--SKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGST 627
Query: 609 LTADL--LSVDAFAAP-SPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSA 665
L S +++P SP TT PA + SSGV + S+ S +P S ++
Sbjct: 628 TKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSE------ESTTSHSRPGSTHTTA--- 678
Query: 666 SADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLL 725
F GS P S + A ++ P +P ++++SS P
Sbjct: 679 -------FPGSTTMPGLSQESTASHSSPGPTDTT---LSPGSTTASSLGPE--------- 719
Query: 726 MPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDL----Q 781
T +++P + + + SS S L +G+TT++G+
Sbjct: 720 YTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHS 779
Query: 782 W-NAGEKKLTGGANWQPKVAPATWSAGVPPSAP 813
W ++ + + V P+T S G P S P
Sbjct: 780 WPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIP 812
Score = 55.8 bits (133), Expect = 2e-07
Identities = 114/506 (22%), Positives = 185/506 (36%), Gaps = 74/506 (14%)
Query: 306 SPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAA 365
S T N+T A T +S P F+ +V T ++ L +SG + +
Sbjct: 167 STVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHF-LDSSTNSGHSEEST 225
Query: 366 APAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEP-TPPTTTAEIATASASA 424
P A G T + PS + S F EP T P T+A + T +
Sbjct: 226 VSHSGPGATGTTLF---------------PSHSATS-VFVGEPKTSPITSASMETTALPG 269
Query: 425 STTTTVTAVTAEVDLFGDAFAASP-------GEAPAASEGAAAPAT-----PTPVAAALD 472
STT TA + F +SP A S G + +T P P
Sbjct: 270 STT------TAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAF 323
Query: 473 ACSGNDPFAPSEGSA-EAAPELDLFAMKPPETSVPVVTPTASTAPPVP-----ATAPSPA 526
S P E +A + P + P T+ + P ++T P P
Sbjct: 324 PDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNT 383
Query: 527 PAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSI 586
A+T ++ + TT S +++TT F + S+ + + AP + +
Sbjct: 384 TTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTF-QSWPSSKDTSPAPSGTTSAFV 442
Query: 587 DLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAP------SPATTASPAKVDSSGVID 640
L ST SSP ++P S ++ L + P + ATT PA+ +SG ++
Sbjct: 443 KL-STTYHSSP--SSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVE 499
Query: 641 LFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFM-APSPSPVTPAQNNLLQPNFEA 699
S S +S++S ++ A F GS S +P T A L ++ +
Sbjct: 500 ESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAA--LAHTSYHS 557
Query: 700 AFGTT-------PSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKA 752
+ G+T ST S S + D + T+ PAG V + +P+ +S +
Sbjct: 558 SLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGS 617
Query: 753 LGSDLDSSLASLVGNLGISGTTTKKG 778
+ + + G+TTK G
Sbjct: 618 MET------------TALPGSTTKPG 631
Score = 50.8 bits (120), Expect = 6e-06
Identities = 86/407 (21%), Positives = 152/407 (37%), Gaps = 42/407 (10%)
Query: 283 NTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVST 342
+T PG+ + P + S + + +S+ TI +SPP +T SA V T
Sbjct: 4745 STAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTI-SSPP----STTSALVEEPT 4799
Query: 343 SKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISD 402
S SS G A P +G + ++ +P+ S
Sbjct: 4800 SYHSSP----------GSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSG 4849
Query: 403 PFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPA 462
A T + + T AS +TT ++A + L+ + + +PA+ ++
Sbjct: 4850 RIAESTTFYISPGSMETTLASTATTPGLSAKSTI--LYSSSRSPDQTLSPASMTSSSISG 4907
Query: 463 TPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSV---PVVTPTASTAPPVP 519
PT + + ++ + F S ++ + E F KP T P T+S A
Sbjct: 4908 EPTSLYSQAES-THTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFT 4966
Query: 520 ATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDL---------FES 570
P A++ + A+T + +TT ++ +T A + F
Sbjct: 4967 TPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPD 5026
Query: 571 TPEVAAAPKPDAAPSIDLFS-TDAF--SSPPQGASPVPESSLTADLLS--VDAFAAPSPA 625
+P P + D+ + AF SS G +P+P S +DL+ + +PSP
Sbjct: 5027 SPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYISPSPT 5086
Query: 626 -TTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLA 671
TT PA +SG+ + S+ P+ + S+ S + LA
Sbjct: 5087 YTTLFPASSSTSGLTE------ESTTFHTSPSFTSTIVSTESLETLA 5127
Score = 47.0 bits (110), Expect = 8e-05
Identities = 143/686 (20%), Positives = 236/686 (34%), Gaps = 91/686 (13%)
Query: 265 PDLTQAPSSLMETLEQHL---NTLEGKKPGNNEGS--GAPSPLSKSSPATTVTS---PNS 316
PD T P E+ H +T PG S G S SSP T T+ N+
Sbjct: 324 PDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNT 383
Query: 317 TPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLL-DLQPD-FSSGGAAAAAAPAPPPPAG 374
T + ++ S PV +S P +T PSS + +P F S ++ +PAP
Sbjct: 384 TTSGLLEASTPVH----SSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAP----S 435
Query: 375 GATAWGDLLGEDSLAALSSVPS---EAQISDPFAPEPTPPTTTAEIATASASASTTTTVT 431
G T+ L ++ SS P+ A + E + P ++ +ATA+ + +
Sbjct: 436 GTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATS 495
Query: 432 AVTAEVDLFGDAFAASPG-----------------EAPAASEGAAA---PATPTPVAAAL 471
E A+ SPG E A G+ +TP+ AA
Sbjct: 496 GHVEE----STAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAAL- 550
Query: 472 DACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAA 531
+ + S GS E D + + + ++P AT PA + +
Sbjct: 551 ----AHTSYHSSLGSTETTHFRDSSTISGRSEE----SKASHSSPDAMATTVLPAGSTPS 602
Query: 532 AAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFES---TPEVAAAPKPDAAPSIDL 588
+ + ++ + T+A +T P L F S +P+ P + +
Sbjct: 603 VLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSE 662
Query: 589 FSTDAFSSPPQGASPVPESSLTADLLSVDAFA---APSPA-TTASPAKVDSSGVIDLFGD 644
ST + S P + S T LS ++ A +P P TT SP +S + G
Sbjct: 663 ESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSL----GP 718
Query: 645 AFGSSASEP--QPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFG 702
+ + S P + +++AS L A SP + + F
Sbjct: 719 EYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFH 778
Query: 703 TTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLA 762
+ PS+ + P+ + P+ G P S +P + A S G L
Sbjct: 779 SWPSSKDTRPAPPTTTSA---FVEPSTTSHGSP---SSIPTTHISARSTTSG--LVEEST 830
Query: 763 SLVGNLGISGTT-TKKGDLQWNAGEKKLTGGANWQPKV--APATWSAGV--PPSAPLQGA 817
+ + G + T + D GE+ T ++ + AP+T SA V P S
Sbjct: 831 TYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPG 890
Query: 818 VPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPV-------MFAQPMMRPPFGA 870
T+ P + + TG ++P + P+
Sbjct: 891 STATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET 950
Query: 871 AAVPGTQLSPS----PTPASQSPKKP 892
A+PG+ +P T SP+ P
Sbjct: 951 TALPGSTTTPGLSERSTTFHSSPRSP 976
Score = 36.6 bits (83), Expect = 0.11
Identities = 61/255 (23%), Positives = 91/255 (35%), Gaps = 53/255 (20%)
Query: 268 TQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPP 327
T P+S + +T KPG+ E + +P ++ SS A T+P+S P + T P
Sbjct: 4922 TAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSP 4981
Query: 328 VDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDS 387
AS VP S+ S+ +SS G+ A
Sbjct: 4982 ------ASTTVP-GLSEESTTF------YSSPGSTETTA--------------------- 5007
Query: 388 LAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAAS 447
+ +++ +Q S PF P P T + A+ TTT + + DA +
Sbjct: 5008 FSHSNTMSIHSQQSTPF---PDSPGFTHTVLPATL---TTTDIGQESTAFHSSSDATGTT 5061
Query: 448 PGEA-PAASEGAAAPAT----PTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPE 502
P A AS+ P T P+P L F S ++ E F P
Sbjct: 5062 PLPARSTASDLVGEPTTFYISPSPTYTTL--------FPASSSTSGLTEESTTFHTSPSF 5113
Query: 503 TSVPVVTPTASTAPP 517
TS V T + T P
Sbjct: 5114 TSTIVSTESLETLAP 5128
Score = 33.9 bits (76), Expect = 0.71
Identities = 75/365 (20%), Positives = 119/365 (32%), Gaps = 71/365 (19%)
Query: 534 AATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDA 593
+AT+ T+ TSA+ TTA P L E + ++P+
Sbjct: 243 SATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPR-------------- 288
Query: 594 FSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEP 653
SP + SP +S S + + P P T AF S + P
Sbjct: 289 --SPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTI----------------AFPDSTTMP 330
Query: 654 QPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSF 713
+ ++ +S S G + SP TP+ F ++ G T +T
Sbjct: 331 GVSQESTASHSIP-------GSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLP--- 380
Query: 714 DPSVFDGLGDLLMPTMAPAGQP----APVSMVPPSPAMAASKALGSDLDSSLASLVGNLG 769
D + GL + P + G P +P S ++ S D+S A
Sbjct: 381 DNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAP------ 434
Query: 770 ISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPAT-WSAG------VPPSAPLQGAVPPTS 822
SGTT + KL+ + P P T +SA S P+ + T+
Sbjct: 435 -SGTT---------SAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATA 484
Query: 823 SVPPVAGAPSVG--QPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSP 880
+ PP A + + G + + P T P+ F + +P
Sbjct: 485 TTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTP 544
Query: 881 SPTPA 885
S T A
Sbjct: 545 STTAA 549
Score = 30.4 bits (67), Expect = 7.8
Identities = 58/267 (21%), Positives = 94/267 (35%), Gaps = 35/267 (13%)
Query: 298 APSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVST---SKPSSDLLDLQP 354
+P+ ++ SS + TS S T T+ P T S ST SKP S L P
Sbjct: 4896 SPASMTSSSISGEPTSLYSQAESTHTTAFPAS--TTTSGLSQESTTFHSKPGSTETTLSP 4953
Query: 355 DFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTT 414
+ + A P G A + A ++VP ++ S F P TT
Sbjct: 4954 GSITTSSFAQEFTTPHSQPGSALSTVS-------PASTTVPGLSEESTTFYSSPGSTETT 5006
Query: 415 AEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDAC 474
A S + T++ + + F D+ + PA T ++ DA
Sbjct: 5007 A--------FSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDA- 5057
Query: 475 SGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAA 534
+G P +++ E F + P T + ++ST+
Sbjct: 5058 TGTTPLPARSTASDLVGEPTTFYISPSPTYTTLFPASSSTS--------------GLTEE 5103
Query: 535 ATTAATAAATTTTTTSAATATTAPPAL 561
+TT T+ + T+T S + T P L
Sbjct: 5104 STTFHTSPSFTSTIVSTESLETLAPGL 5130
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 76.3 bits (186), Expect = 1e-13
Identities = 122/547 (22%), Positives = 195/547 (35%), Gaps = 63/547 (11%)
Query: 298 APSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFS 357
A + S S AT ++P + P + TSP AT+S A S+ + ++ L P +
Sbjct: 4730 ATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTL----PVLT 4785
Query: 358 SGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAAL-------SSVPSEAQISDPFAPEPTP 410
S + A P P+ G L + + SS P S + T
Sbjct: 4786 STATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATT 4845
Query: 411 PTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAA 470
T+ +T S++ TT +T +T A P P+++ G T A
Sbjct: 4846 TRATSSTSTPSSTPGTTWILTELTTAATTTA---ATGPTATPSSTPGTTWILTELTTTAT 4902
Query: 471 LDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVA 530
A +G S + + P + + P T+ V PT STA A + P V+
Sbjct: 4903 TTASTG------STATPSSTPGTT-WILTEPSTTATVTVPTGSTATASSTQATAGTPHVS 4955
Query: 531 AAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFS 590
A T ++ AT +++ ATA PAL ST A A PS L +
Sbjct: 4956 TTATTPTVTSSKATPSSSPGTATAL---PAL-------RSTATTPTATSFTAIPSSSLGT 5005
Query: 591 TDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSA 650
T ++ Q +P S A PS ++P V +S V+ G++
Sbjct: 5006 T--WTRLSQTTTPTATMST----------ATPS----STPETVHTSTVLTATATTTGATG 5049
Query: 651 SEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSS 710
S P+S ++ + G + PS SP T L P TTP ++ S
Sbjct: 5050 SVATPSSTPGTAHTTKVPTTTTTGFT-ATPSSSPGTA----LTPPT------TTPMSTMS 5098
Query: 711 SSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGI 770
+ S + + T A S PS + ++ L ++L ++ A+ G
Sbjct: 5099 TIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRIL-TEL-TTTATTTAATGS 5156
Query: 771 SGTTTKKGDLQWNAGEKKLTGGA---NWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPV 827
+ T + W E A +T P A PT++ V
Sbjct: 5157 TATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTV 5216
Query: 828 AGAPSVG 834
+ +VG
Sbjct: 5217 PSSSTVG 5223
Score = 75.5 bits (184), Expect = 2e-13
Identities = 125/543 (23%), Positives = 195/543 (35%), Gaps = 95/543 (17%)
Query: 265 PDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNS-----TPA 319
P T + L T +T P + G+ AP P +SPATT T+ +S +
Sbjct: 4717 PGTTWILTELTTTATTTASTGSTATPSSTPGT-APPPKVLTSPATTPTATSSKATSSSSP 4775
Query: 320 KTIDTSPPVDLFATASAA----------------VPVSTSKPSSDLLDLQPD-------- 355
+T T P + AT S A +P T+ P + + + P
Sbjct: 4776 RTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHT 4835
Query: 356 ----FSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAAL-----------SSVPSEAQI 400
+ A + P + T W +L E + AA SS P I
Sbjct: 4836 STVLTTKATTTRATSSTSTPSSTPGTTW--ILTELTTAATTTAATGPTATPSSTPGTTWI 4893
Query: 401 SDPFAPEPTPPTTTAEIATASASASTTTTVT--AVTAEVDL-FGDAFAASPGEAPAASEG 457
T +T AT S++ TT +T + TA V + G AS +A A +
Sbjct: 4894 LTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPH 4953
Query: 458 AAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVV--------- 508
+ AT TP + A + P G+A A P L A P TS +
Sbjct: 4954 VSTTAT-TPTVTSSKATPSSSP-----GTATALPALRSTATTPTATSFTAIPSSSLGTTW 5007
Query: 509 -------TPTASTAPPVPATAPSP--APAVAAAAAATTAATAAATTTTTTSAATATTAPP 559
TPTA+ + P++ P V A A TT AT + T ++T TT P
Sbjct: 5008 TRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVP 5067
Query: 560 ALDIFGDLFESTPEVA--AAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVD 617
G F +TP + A P + ST SS PE++ T+ +L+
Sbjct: 5068 TTTTTG--FTATPSSSPGTALTPPTTTPMSTMSTIHTSS-------TPETTHTSTVLTTT 5118
Query: 618 AFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLL---AGFG 674
A + +TA+P+ + G + + ++ + S A SS+ +
Sbjct: 5119 ATMTRATNSTATPS--STLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTI 5176
Query: 675 GSFMAPSPSPVTPAQ--NNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPA 732
+ M P+ S T + P T P+ ++S+ S +G P + P+
Sbjct: 5177 ATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSST---VGTTRTPAVLPS 5233
Query: 733 GQP 735
P
Sbjct: 5234 SLP 5236
Score = 74.7 bits (182), Expect = 4e-13
Identities = 138/626 (22%), Positives = 200/626 (31%), Gaps = 138/626 (22%)
Query: 299 PSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSS 358
PS + SS AT ++P +T T T+ T S A+P ST
Sbjct: 3555 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTP--------------- 3599
Query: 359 GGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIA 418
APPP +TA T PT T+ A
Sbjct: 3600 -------GTAPPPKVLTSTA------------------------------TTPTATSSKA 3622
Query: 419 TASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGND 478
T+S+S T TT+ +T+ A++ A TP P G
Sbjct: 3623 TSSSSPRTATTLPVLTS-----------------TATKSTATSFTPIP-----SFTLGTT 3660
Query: 479 PFAPSEGSAEAAPELDLFAMKPPE---TSVPVVTPTASTAPPVPATAPSPAPAVAAAAAA 535
P + + A + PE TS + T +T + PS P
Sbjct: 3661 GTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTP-------G 3713
Query: 536 TTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFS 595
TT TT TT+AAT TA P+ T + P A ++ ST S
Sbjct: 3714 TTWILTELTTAATTTAATGPTATPSST------PGTTWILTEPSTTATVTVPTGSTATAS 3767
Query: 596 SPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQP 655
S + TA L V A +P +S A SS A S+A+ P
Sbjct: 3768 S----------TRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTA 3817
Query: 656 ASQAASSSSA--------SADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGT---- 703
S A SS+ S S PS +P T + +L T
Sbjct: 3818 TSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVA 3877
Query: 704 ----TPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPP-------SPAMAASKA 752
TP T+ ++ + G T P+ P ++ PP +P S
Sbjct: 3878 TPSSTPGTAHTTKVPTTTTTGF------TATPSSSPG-TALTPPVWISTTTTPTTRGSTV 3930
Query: 753 LGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQ--PKVAPATWSAGVPP 810
S + + + L + TT G + + + +G + P T +PP
Sbjct: 3931 TPSSIPGTTHTAT-VLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLPP 3989
Query: 811 SAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFA-QPMMR---- 865
S+P TS+ + G + +P PA T P + + P R
Sbjct: 3990 SSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTES 4049
Query: 866 PPFGAAAVPGTQLSPSPTPASQSPKK 891
PP PG S T A+ +P K
Sbjct: 4050 PPSPGTTTPGHTRGTSRTTATATPSK 4075
Score = 72.4 bits (176), Expect = 2e-12
Identities = 108/456 (23%), Positives = 163/456 (35%), Gaps = 58/456 (12%)
Query: 300 SPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSG 359
+P++ S ++P +T T+ T+ AT+S + P ST + L +L ++
Sbjct: 3669 TPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELT---TAA 3725
Query: 360 GAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIAT 419
AA P P + T W +L E S A +VP+ + T +T A T
Sbjct: 3726 TTTAATGPTATPSSTPGTTW--ILTEPSTTATVTVPTGSTA--------TASSTRATAGT 3775
Query: 420 ASASASTTTTVTAVTAEVDLFGDAFAASPGEAPA--ASEGAAAPATPTPVAAALDACSGN 477
ST TT T +++ ++SPG A A A A T T V A + G
Sbjct: 3776 LKVLTSTATTPTVISSRATP-----SSSPGTATALPALRSTATTPTATSVTAIPSSSLGT 3830
Query: 478 DPFAPSEGSAEAAPELDLFAMKPPET---SVPVVTPTASTAPPVPATAPSPAPAVAAAAA 534
S+ + A PET S + T T +T PS P A
Sbjct: 3831 AWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTK 3890
Query: 535 ATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAF 594
T T T T ++S TA T P + V + P + + +T
Sbjct: 3891 VPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTT- 3949
Query: 595 SSPPQGASPVPESSLTADLLSVDAFAAPSPATTA----------SPAKV------DSSGV 638
++ G+ P SS S P P TTA SP V +SG+
Sbjct: 3950 TTVATGSMATPSSSTQT---SGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGI 4006
Query: 639 IDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMA---PSPSPVTPAQNNLLQP 695
+ S+ + PA+ +++ ++ L + S PSP TP
Sbjct: 4007 LGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSR 4066
Query: 696 NFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAP 731
A TPS + +S+ PS PT AP
Sbjct: 4067 TTATA---TPSKTRTSTLLPS---------SPTSAP 4090
Score = 71.2 bits (173), Expect = 4e-12
Identities = 103/442 (23%), Positives = 154/442 (34%), Gaps = 80/442 (18%)
Query: 296 SGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVST--SKPSSDLLDLQ 353
S PS + SS AT ++P +T T T+ +T S A P ST + P +L
Sbjct: 2576 SHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTT 2635
Query: 354 PDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEA-QISDPFAPEPTPPT 412
+ ++ A + P A A + +++ +PS + + + T PT
Sbjct: 2636 ATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPT 2695
Query: 413 TTAEIATASASASTTTTVTAVTAEVDLFG-DAFAASPGEAPAASEGAAAPATPTPVAAAL 471
T AT S++ T T T +TA G A+P P + P T T A
Sbjct: 2696 ATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTAT 2755
Query: 472 DACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAA 531
+ S A+ PP TPT + P++ P
Sbjct: 2756 PSSSPGT------------------ALTPPVWISTTTTPTTRGSTVTPSSIPG------- 2790
Query: 532 AAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFST 591
T TA TTTTT+ AT + A P+ S+ + + P+ + +T
Sbjct: 2791 -----TTHTATVLTTTTTTVATGSMATPS---------SSTQTSGTTHTPPVPN-TMATT 2835
Query: 592 DAFSSPPQGASPVPE--SSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSS 649
S PP V +S T+ +L PS T+ + A ++G A
Sbjct: 2836 HGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAA--TTGTTQHSTPAL--- 2890
Query: 650 ASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSS 709
S P P+S+ S PSP TP A TPS +
Sbjct: 2891 -SSPHPSSRTTES----------------PPSPGTTTPGHTTATSRTTATA---TPSKTR 2930
Query: 710 SSSFDPSVFDGLGDLLMPTMAP 731
+S+ PS PT AP
Sbjct: 2931 TSTLLPS---------SPTSAP 2943
Score = 70.1 bits (170), Expect = 9e-12
Identities = 105/465 (22%), Positives = 168/465 (36%), Gaps = 66/465 (14%)
Query: 296 SGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAA----------------VP 339
S A +P + SS AT+ +SP +T T P + AT S A +P
Sbjct: 3610 STATTPTATSSKATSSSSP-----RTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLP 3664
Query: 340 VSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQ 399
T+ P + + + P + + AT+ S++ SS P
Sbjct: 3665 EQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATS--------SMSTPSSTPGTTW 3716
Query: 400 ISDPFAPEPTPPTTTAEIATASASASTTTTVT--AVTAEVDL-FGDAFAASPGEAPAASE 456
I T T AT S++ TT +T + TA V + G AS A A +
Sbjct: 3717 ILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTL 3776
Query: 457 GAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVV-------- 508
TP + A + P G+A A P L A P TSV +
Sbjct: 3777 KVLTSTATTPTVISSRATPSSSP-----GTATALPALRSTATTPTATSVTAIPSSSLGTA 3831
Query: 509 --------TPTASTAPPVPATAPSP--APAVAAAAAATTAATAAATTTTTTSAATATTAP 558
TPTA+ + P++ P V TT AT + T ++T TT
Sbjct: 3832 WTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKV 3891
Query: 559 PALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASP--VPESSLTADLL-- 614
P G F +TP +++P P + + +T ++ +P +P ++ TA +L
Sbjct: 3892 PTTTTTG--FTATP--SSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTT 3947
Query: 615 SVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFG 674
+ A S AT +S + + + ++ P S + +A +G
Sbjct: 3948 TTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGIL 4007
Query: 675 GSFMAPSPSPV---TPAQNNLLQPNFEAAFGTTPSTSSSSSFDPS 716
G+ PS V TPA + A + +S ++ PS
Sbjct: 4008 GTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPS 4052
Score = 66.6 bits (161), Expect = 1e-10
Identities = 96/422 (22%), Positives = 149/422 (35%), Gaps = 43/422 (10%)
Query: 299 PSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVST-------SKPSSDLLD 351
PS + SS AT ++P +T T T+ +T S A P ST ++PS+
Sbjct: 4200 PSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 4259
Query: 352 LQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPP 411
P S+ A++ A A P TA + SS P A T P
Sbjct: 4260 TVPTGSTATASSTQATAGTPHVS-TTATTPTVTSSKATPFSS-PGTATALPALRSTATTP 4317
Query: 412 TTTAEIATASASA---------STTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPA 462
T T+ A S+S +TT T T TA + S A+ A +
Sbjct: 4318 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGS 4377
Query: 463 TPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATA 522
TP + A + P + G A PP TPT S + P++
Sbjct: 4378 VATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSV 4437
Query: 523 P--SPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFG-----DLFESTPEVA 575
P + P V T A + AT +++T + T PP + L S+P
Sbjct: 4438 PGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTV 4497
Query: 576 AAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPA--TTASPAKV 633
A T + P G S P ++ S A ++P P+ TT SP
Sbjct: 4498 RTAWTSATSG--TLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSP 4555
Query: 634 DSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLL 693
++ G + + + + A S + ++ LL +P+ +P+T
Sbjct: 4556 GTT--------TPGHTTATSRTTATATPSKTRTSTLLPS------SPTSAPITTVVTTGC 4601
Query: 694 QP 695
+P
Sbjct: 4602 EP 4603
Score = 65.1 bits (157), Expect = 3e-10
Identities = 140/653 (21%), Positives = 220/653 (33%), Gaps = 131/653 (20%)
Query: 297 GAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDF 356
G SP S+ T T +TPA + + + P A++ +P ++ P +
Sbjct: 2349 GLTSPRYTSTLGTATTGGPTTPAGSTEPTVP----GVATSTLPTRSALPGTT-------- 2396
Query: 357 SSGGAAAAAAPAPPP---PAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTT 413
G+ P+ PP P AT+ G S A S P ++ PT
Sbjct: 2397 ---GSLGTWRPSQPPTLAPTTMATSRARPTGTASTA--SKEPLTTSLA---------PTL 2442
Query: 414 TAEIATASASASTT---TTVTAVTAEVDLFGDAFAASPGE------APAASEGAAAPATP 464
T+E++T+ A ST TT++ +T G E + G A
Sbjct: 2443 TSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDME 2502
Query: 465 TPVAAALDACSGNDPFAPS--EGSAEAAPELDLFAMKPPETSVPVVTPTA---------- 512
T + A G +AP E AE PE+ + + T T
Sbjct: 2503 T--FENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFN 2560
Query: 513 ---------------STAPPVPATAPSPAPAVAAAAA------ATTAATAAATTTTTTSA 551
S P PAT+ + P+ TTA T A+T +T T
Sbjct: 2561 MCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPT 2620
Query: 552 ATATTAPPALDIFGDLFESTPEVAA-----APKPDAAPSIDLFSTDAFSSPPQGASPVPE 606
+T TAPP + +TP V + + P A ++ + A + +P+P
Sbjct: 2621 STLRTAPPPKVL--TTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPS 2678
Query: 607 SSLTADLLSVDAFAAPSPA-TTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSA 665
SSL + P+ +TA+P SS E S ++++
Sbjct: 2679 SSLGTTWTRLSQTTTPTATMSTATP-----------------SSTPETAHTSTVLTATAT 2721
Query: 666 SADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLL 725
+ G GS PS +P T A + F TPS+S ++ P V+ +
Sbjct: 2722 T----TGATGSVATPSSTPGT-AHTTKVPTTTTTGFTATPSSSPGTALTPPVW--ISTTT 2774
Query: 726 MPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAG 785
PT G S +P + A L + TT G + +
Sbjct: 2775 TPT--TRGSTVTPSSIPGTTHTATV-----------------LTTTTTTVATGSMATPSS 2815
Query: 786 EKKLTGGANWQ--PKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMP 843
+ +G + P T +PPS+P TS+ + G + +P
Sbjct: 2816 STQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHT 2875
Query: 844 PAGTGMPMMPQQPVMFA-QPMMR----PPFGAAAVPGTQLSPSPTPASQSPKK 891
A T P + + P R PP PG + S T A+ +P K
Sbjct: 2876 LAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSK 2928
Score = 63.5 bits (153), Expect = 8e-10
Identities = 78/314 (24%), Positives = 122/314 (38%), Gaps = 26/314 (8%)
Query: 290 PGNNEGSGAPSPLSKSSPAT-TVTSPNSTPAKTIDT-----SPPVDLFATASAAVPVSTS 343
P ++ G+ P +S+ T T TS + P+ ++ T S AT S A P ST
Sbjct: 4970 PSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTP 5029
Query: 344 KPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDP 403
+ L ++ GA + A P TA + + ++ PS + +
Sbjct: 5030 ETVHTSTVLTATATTTGATGSVATPSSTPG---TAHTTKVPTTTTTGFTATPSSSPGTAL 5086
Query: 404 FAPEPTPPTTTAEIATASASAST-TTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPA 462
P TP +T + I T+S +T T+TV TA + A + P+++ G
Sbjct: 5087 TPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTR-----ATNSTATPSSTLGTTRIL 5141
Query: 463 TPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATA 522
T A A +G S + + P + + P T V+ PT STA
Sbjct: 5142 TELTTTATTTAATG------STATLSSTPGTT-WILTEPSTIATVMVPTGSTATASSTLG 5194
Query: 523 PSPAPAVAAAAAATTAATAAATTTTTTSAATATTA--PPALDIFGDLFESTPEVAAAPKP 580
+ P V A ATA+ +++T T T A P +L F + + V +P
Sbjct: 5195 TAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPTF-SVSTVSSSVLTTLRP 5253
Query: 581 DAAPSIDLFSTDAF 594
PS FST F
Sbjct: 5254 TGFPS-SHFSTPCF 5266
Score = 61.2 bits (147), Expect = 4e-09
Identities = 114/446 (25%), Positives = 155/446 (34%), Gaps = 73/446 (16%)
Query: 305 SSPATTVTS-PNSTPAKTID----TSPPVDLFATASAAVPVST-------SKPSSDLLDL 352
S+PAT+ T+ P+STP T T+ +T S A P ST ++PS+
Sbjct: 3054 STPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVT 3113
Query: 353 QPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPT 412
P S+ A++ A A P TA + SS P A T PT
Sbjct: 3114 VPTGSTATASSTQATAGTPHV-STTATTPTVTSSKATPFSS-PGTATALPALRSTATTPT 3171
Query: 413 TTAEIATASASASTT-TTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAAL 471
T+ A S+S TT T ++ T A +S E S AT T ++
Sbjct: 3172 ATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSV 3231
Query: 472 DACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTP-TASTAPPVPATAPSP---AP 527
PS A L T+ P +P TA T P +T +P
Sbjct: 3232 --------ATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGS 3283
Query: 528 AVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSID 587
V ++ T T TTTTT+ AT + A P+ TP V P A
Sbjct: 3284 TVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPV---PNTTA----- 3335
Query: 588 LFSTDAFSSPPQGASPVPE--SSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDA 645
+T S P V +S T+ L PS T+ +PA ++G A
Sbjct: 3336 --TTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAA--TTGTTQHSTPA 3391
Query: 646 FGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTP 705
S P P+S+ S PSP TP A TP
Sbjct: 3392 L----SSPHPSSRTTES----------------PPSPGTTTPGHTRATSRTTATA---TP 3428
Query: 706 STSSSSSFDPSVFDGLGDLLMPTMAP 731
S + +S+ PS PT AP
Sbjct: 3429 SKTRTSTLLPS---------SPTSAP 3445
Score = 61.2 bits (147), Expect = 4e-09
Identities = 129/642 (20%), Positives = 208/642 (32%), Gaps = 102/642 (15%)
Query: 268 TQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKS---SPATTVTSPNSTPAKTIDT 324
+ P++ T + L P + PSP + + + T+ T+ +TP+KT +
Sbjct: 4020 SHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTS 4079
Query: 325 SPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLG 384
+ L ++ + P++T + +P + + P P P G + ++
Sbjct: 4080 T----LLPSSPTSAPITTVVTTG----CEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRA 4131
Query: 385 EDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTT--------VTAVTAE 436
+ E + A P ++ S E
Sbjct: 4132 AGGAVCEQPLGLECRAQ---AQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYE 4188
Query: 437 VDLFGDAFAASPGEAPAASEGAAAPATP--TPVAAALDACSGNDPFAPSEGSAEAAPELD 494
+ +F + P PA S A +TP T + L + S + + P
Sbjct: 4189 IRVFCCNYGHCPS-TPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTT 4247
Query: 495 LFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATA 554
+ + P T+ V PT STA A + P V+ A T ++ AT ++ ATA
Sbjct: 4248 -WILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATA 4306
Query: 555 TTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLL 614
PAL ST A A PS L +T ++ Q +P S TA
Sbjct: 4307 L---PAL-------RSTATTPTATSFTAIPSSSLGTT--WTRLSQTTTPTATMS-TATPS 4353
Query: 615 SVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFG 674
S A S T + ++G S + P A ++ GF
Sbjct: 4354 STPETAHTSTVLTTTATTTRATG-----------SVATPSSTPGTAHTTKVPTTTTTGFT 4402
Query: 675 GSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQ 734
+ PS SP T P + TTP+TS S+ + P+ P
Sbjct: 4403 ---VTPSSSPGTART-----PPVWISTTTTPTTSGST-------------VTPSSVPGTT 4441
Query: 735 PAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGAN 794
P + + +A S+A+ + SGTT
Sbjct: 4442 HTPTVLTTTTTTVATG---------SMATPSSSTQTSGTTHTPP---------------- 4476
Query: 795 WQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQ 854
P T + PS+P TS+ G + +P G PA T
Sbjct: 4477 -VPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHS 4535
Query: 855 QPVMFA-QPMMR----PPFGAAAVPGTQLSPSPTPASQSPKK 891
P + + P R PP PG + S T A+ +P K
Sbjct: 4536 TPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSK 4577
Score = 59.7 bits (143), Expect = 1e-08
Identities = 143/647 (22%), Positives = 224/647 (34%), Gaps = 109/647 (16%)
Query: 302 LSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGA 361
LS SSP T T+ S + T+ T+ + +T ++ P +T+ + P SS
Sbjct: 4489 LSPSSPHTVRTAWTSATSGTLGTTHITEP-STGTSHTPAATTGTTQHST---PALSSPHP 4544
Query: 362 AAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATAS 421
++ +PP P G T G A ++ PS+ + S PT T + T
Sbjct: 4545 SSRTTESPPSP--GTTTPGHTTATSRTTA-TATPSKTRTSTLLPSSPTSAPITTVVTTGC 4601
Query: 422 ASASTTTTVTAVT--------AEVDLFGDAFAASPG--EAPAASE--GAAAPATPTPVAA 469
+ + + D + + AA E P E A P P
Sbjct: 4602 EPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELG 4661
Query: 470 ALDACS-------------------------------GNDPFAPSEGSAEAAPELD--LF 496
+ CS G+ P P+ S +
Sbjct: 4662 QVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTW 4721
Query: 497 AMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATT 556
+ T+ T STA P +P P V + A T AT++ T+++ S TATT
Sbjct: 4722 ILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSS-SPRTATT 4780
Query: 557 APPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPV-----------P 605
P + ST + A PS L +T P Q +PV P
Sbjct: 4781 LP--------VLTSTATKSTATSVTPIPSSTLGTTGTL--PEQTTTPVATMSTIHPSSTP 4830
Query: 606 ESSLTADLLSVDAFAAPSPATTASPAKVDSSGVI--DLFGDAFGSSASEP------QPAS 657
E++ T+ +L+ A + ++T++P+ + I +L A ++A+ P P +
Sbjct: 4831 ETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGT 4890
Query: 658 QAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGT-TPSTSSSSSFDPS 716
+ + GS PS +P T L +P+ A T ST+++SS
Sbjct: 4891 TWILTELTTTATTTASTGSTATPSSTPGTTW--ILTEPSTTATVTVPTGSTATASS---- 4944
Query: 717 VFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTK 776
T A AG P VS +P + +SKA S + +L + T T
Sbjct: 4945 -----------TQATAGTP-HVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTA 4992
Query: 777 KGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQP 836
+ T Q AT S P S P TS+V A A + G
Sbjct: 4993 TSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTP---ETVHTSTV-LTATATTTGAT 5048
Query: 837 GAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPT 883
G+ P + G + P P ++ PGT L+P T
Sbjct: 5049 GS-VATPSSTPGTAHTTKVPTTTTTGFTATP---SSSPGTALTPPTT 5091
Score = 58.2 bits (139), Expect = 3e-08
Identities = 149/689 (21%), Positives = 223/689 (32%), Gaps = 122/689 (17%)
Query: 296 SGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPD 355
S +P ++ S T + P +T T+ T+ + AT S A P S+S +S P
Sbjct: 2771 STTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTV-ATGSMATP-SSSTQTSGTTHTPPV 2828
Query: 356 FSSGGAAAAAAPAPPPPAGGATAW----GDLLG----------------------EDSLA 389
++ + P P TAW +LG + S
Sbjct: 2829 PNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTP 2888
Query: 390 ALSSV-PSEAQISDPFAPEPTPP--TTTAEIATASASASTT---------------TTVT 431
ALSS PS P +P T P TT TA+A+ S T TTV
Sbjct: 2889 ALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVV 2948
Query: 432 AVTAE--------VDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPS 483
+ E +D S G+ S AA L+ + P P
Sbjct: 2949 TMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPL 3008
Query: 484 EGSA---EAAPELDLFAMKPPETS---------VPVVTPTASTAPPVPATAPSPAPAVAA 531
E + + L + + V P PAT+ + P+
Sbjct: 3009 RELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPS--- 3065
Query: 532 AAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFST 591
+ TT TTT TT+ +T +TA P+ T + P A ++ ST
Sbjct: 3066 STPGTTWILTELTTTATTTESTGSTATPSST------PGTTWILTEPSTTATVTVPTGST 3119
Query: 592 DAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSAS 651
A +S Q + P S T A +P T+S A SS A S+A+
Sbjct: 3120 -ATASSTQATAGTPHVSTT----------ATTPTVTSSKATPFSSPGTATALPALRSTAT 3168
Query: 652 EPQPASQAASSSSA--------SADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGT 703
P S A SS+ S S PS +P T + +L T
Sbjct: 3169 TPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGAT 3228
Query: 704 --------TPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVP------PSPAMAA 749
TP T+ ++ + G T P+ P +P +P
Sbjct: 3229 GSVATPSSTPGTAHTTKVLTTTTTGF------TATPSSSPGTARTLPVWISTTTTPTTRG 3282
Query: 750 SKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQ--PKVAPATWSAG 807
S S + + + L + TT G + + + +G + P T
Sbjct: 3283 STVTPSSIPGTTHTPT-VLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRS 3341
Query: 808 VPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFA-QPMMR- 865
+ PS+P TS+ G + +P G PA T P + + P R
Sbjct: 3342 LSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRT 3401
Query: 866 ---PPFGAAAVPGTQLSPSPTPASQSPKK 891
PP PG + S T A+ +P K
Sbjct: 3402 TESPPSPGTTTPGHTRATSRTTATATPSK 3430
Score = 56.2 bits (134), Expect = 1e-07
Identities = 75/299 (25%), Positives = 106/299 (35%), Gaps = 33/299 (11%)
Query: 290 PGNNEGSGAPSPLSKSSPAT-TVTSPNSTPAKTIDT-----SPPVDLFATASAAVPVSTS 343
P ++ G+ P +S+ T T TS + P+ ++ T S AT S A P ST
Sbjct: 3150 PFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTP 3209
Query: 344 KPSSDLLDLQPDFSSGGAAAAAA-PAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISD 402
+ L ++ GA + A P+ P T A SS P A+
Sbjct: 3210 ETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLP 3269
Query: 403 PFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPA 462
+ T PTT T S+ TT T T +T A+P + S P
Sbjct: 3270 VWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPP 3329
Query: 463 TPTPVA-----------------AALDACSGN----DPFAPSEGSAEA-APELDLFAMKP 500
P A A A SG PS G++ A
Sbjct: 3330 VPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHST 3389
Query: 501 PETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTA-ATAAATTTTTTSAATATTAP 558
P S P + + +PP P T P A + TTA AT + T T+T ++ T+AP
Sbjct: 3390 PALSSPHPSSRTTESPPSPGTT---TPGHTRATSRTTATATPSKTRTSTLLPSSPTSAP 3445
Score = 55.8 bits (133), Expect = 2e-07
Identities = 82/366 (22%), Positives = 125/366 (34%), Gaps = 51/366 (13%)
Query: 298 APSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFS 357
A +P SS AT +SP + ATA A+ + + P++ P S
Sbjct: 4285 ATTPTVTSSKATPFSSPGT---------------ATALPALRSTATTPTATSFTAIPSSS 4329
Query: 358 SGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEI 417
G + P A +T A SS P A S T T +
Sbjct: 4330 LGTTWTRLSQTTTPTATMST-----------ATPSSTPETAHTSTVLTTTATTTRATGSV 4378
Query: 418 ATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGN 477
AT S++ T T T F ++SPG A + TPT + + S
Sbjct: 4379 ATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVP 4438
Query: 478 DPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAP-------SPAPAVA 530
+ +M P +S T + PPVP T SP+
Sbjct: 4439 GTTHTPTVLTTTTTTVATGSMATPSSSTQ--TSGTTHTPPVPNTTATTHGRSLSPSSPHT 4496
Query: 531 AAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFS 590
A T+A + TT T +T T+ PA G STP + ++P P S
Sbjct: 4497 VRTAWTSATSGTLGTTHITEPSTGTSHTPAATT-GTTQHSTPAL-SSPHP---------S 4545
Query: 591 TDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSA 650
+ SPP + P + + A + + +T P+ S+ + + ++
Sbjct: 4546 SRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVV-----TTG 4600
Query: 651 SEPQPA 656
EPQ A
Sbjct: 4601 CEPQCA 4606
Score = 47.8 bits (112), Expect = 5e-05
Identities = 131/626 (20%), Positives = 212/626 (33%), Gaps = 61/626 (9%)
Query: 302 LSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGA 361
LS SSP T T+ S + T+ T+ + +T ++ P +T+ + P SS
Sbjct: 3342 LSPSSPHTVRTAWTSATSGTLGTTHITEP-STGTSHTPAATTGTTQHST---PALSSPHP 3397
Query: 362 AAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISD--PFAPEPTPPTTTAEIAT 419
++ +PP P G T G A ++ PS+ + S P +P P TT +
Sbjct: 3398 SSRTTESPPSP--GTTTPGHTRATSRTTA-TATPSKTRTSTLLPSSPTSAPITTVVTMGC 3454
Query: 420 ASASASTTTTVTAVT------AEVDLFGDAFAASPG--EAPAASE--GAAAPATPTPVAA 469
A + + + D + + AA E P E A P P
Sbjct: 3455 EPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELG 3514
Query: 470 ALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAV 529
+ CS + F + E + + + V P PAT+ + P+
Sbjct: 3515 QVVECSLD--FGLVCRNREQVGKFKMCF----NYEIRVFCCNYGHCPSTPATSSTATPS- 3567
Query: 530 AAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPK---PDAAPSI 586
+ TT TT TT+A T +TA P+ STP A PK A
Sbjct: 3568 --STPGTTWILTEQTTAATTTATTGSTAIPS---------STPGTAPPPKVLTSTATTPT 3616
Query: 587 DLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAF 646
S SS P+ A+ +P + TA + +F T + + + +
Sbjct: 3617 ATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMST 3676
Query: 647 GSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSP--------VTPAQNNLLQPNFE 698
+S P+ + ++ + A S PS +P +T A
Sbjct: 3677 IHPSSTPETTHTSTVLTTKATTTRA--TSSMSTPSSTPGTTWILTELTTAATTTAATGPT 3734
Query: 699 AAFGTTPSTS-----SSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKAL 753
A +TP T+ S++ +V G T A AG ++ +P + +S+A
Sbjct: 3735 ATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRAT 3794
Query: 754 GSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAP 813
S + +L + T T + Q AT S P S P
Sbjct: 3795 PSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTP 3854
Query: 814 --LQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAA 871
+ + T++ SV P + G A T A P P G A
Sbjct: 3855 ETVHTSTVLTTTTTTTRATGSVATPSSTPG--TAHTTKVPTTTTTGFTATPSSSP--GTA 3910
Query: 872 AVPGTQLSPSPTPASQSPKKPPAKDP 897
P +S + TP ++ P+ P
Sbjct: 3911 LTPPVWISTTTTPTTRGSTVTPSSIP 3936
Score = 40.8 bits (94), Expect = 0.006
Identities = 39/149 (26%), Positives = 59/149 (39%), Gaps = 7/149 (4%)
Query: 409 TPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVA 468
TPP TT E+ TA+ + + T A AS P SEG +P
Sbjct: 2302 TPPPTT-ELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPR----YT 2356
Query: 469 AALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTAST-APPVPATAPSPAP 527
+ L + P P+ + P + + P +++P T + T P P T
Sbjct: 2357 STLGTATTGGPTTPAGSTEPTVPGVATSTL-PTRSALPGTTGSLGTWRPSQPPTLAPTTM 2415
Query: 528 AVAAAAAATTAATAAATTTTTTSAATATT 556
A + A TA+TA+ TT+ A T T+
Sbjct: 2416 ATSRARPTGTASTASKEPLTTSLAPTLTS 2444
Score = 39.7 bits (91), Expect = 0.013
Identities = 48/173 (27%), Positives = 71/173 (41%), Gaps = 16/173 (9%)
Query: 388 LAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAAS 447
L ++ ++A S P P +P T A A+ +A + + +T+ L G A
Sbjct: 2309 LETATTTTTQALFSTP-QPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTL-GTATTGG 2366
Query: 448 PGEAPAASEGAAAPATPT---PVAAALDACSGN-DPFAPSEGSAEAAPELDLFAMKPPET 503
P PA S P T P +AL +G+ + PS+ A + +P
Sbjct: 2367 P-TTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRARP--- 2422
Query: 504 SVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATT 556
T TASTA P T S AP + + + + A T+ T TT S T TT
Sbjct: 2423 -----TGTASTASKEPLTT-SLAPTLTSELSTSQAETSTPRTETTMSPLTNTT 2469
Score = 34.3 bits (77), Expect = 0.54
Identities = 43/189 (22%), Positives = 57/189 (30%), Gaps = 19/189 (10%)
Query: 522 APSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPD 581
A +P P A TT A +T TS+ T APPA ST V +
Sbjct: 2300 ATTPPPTTELETATTTTTQALFSTPQPTSSPGLTRAPPA---------STTAVPTLSEGL 2350
Query: 582 AAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPS----PATTASPAKVDSSG 637
+P T + G P S + V P+ P TT S S
Sbjct: 2351 TSPRY----TSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQ 2406
Query: 638 VIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQP-- 695
L +S + P + AS + L TP + P
Sbjct: 2407 PPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLT 2466
Query: 696 NFEAAFGTT 704
N + GTT
Sbjct: 2467 NTTTSQGTT 2475
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 75.1 bits (183), Expect = 3e-13
Identities = 77/277 (27%), Positives = 98/277 (35%), Gaps = 57/277 (20%)
Query: 292 NNEGSGAPS-PLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLL 350
N+ + AP+ L + PA + P T+ +PP AA P + + PS
Sbjct: 206 NSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPF-----VGAAAPPAPAAPS---- 256
Query: 351 DLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTP 410
P + AA AAAP PPPPA A L+ P P
Sbjct: 257 ---PPAAPAPAAPAAAPPPPPPAP--------------ATLARPPGH----------PAG 289
Query: 411 PTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAA 470
P T A A+A G + A+P APAA A P P AAA
Sbjct: 290 PPTAAPAVPPPAAAQN--------------GGSAGAAPAPAPAAGGPAGVSGQPGPGAAA 335
Query: 471 LDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVP--VVTPTASTAPPVPATAPSPAP- 527
G +P A P A P ++ V+ PT A P PA P PAP
Sbjct: 336 AAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPG 395
Query: 528 ---AVAAAAAATTAATAAATTTTTTSAATATTAPPAL 561
+ AA + + T T TTS AT P L
Sbjct: 396 TPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVL 432
Score = 72.0 bits (175), Expect = 2e-12
Identities = 118/470 (25%), Positives = 159/470 (33%), Gaps = 91/470 (19%)
Query: 451 APAASEGAAAPATPTPVAAALDA------------CSGNDPFAPSEGSAEAAPELDLFAM 498
A AA AP TP AAA A +G P AP+EG+ AAPE
Sbjct: 35 ASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGR 94
Query: 499 K-----------PPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTT 547
PP P+V A APP P P + + A AA AA
Sbjct: 95 ARPGGGGPQRPGPPSPRRPLVP--AGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEP 152
Query: 548 TTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPES 607
+ P AL + P P P P P G
Sbjct: 153 APAGPAKPAGPAALAA-----RAGPGPGPGPGPGPGPG---------PGKPAGPGAAQTL 198
Query: 608 SLTADLLSVDAFAAPS-------PATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAA 660
+ +A LL+ AAP+ PA K + G + + F +A+ P PA+ +
Sbjct: 199 NGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTV-IQTPPFVGAAAPPAPAAPSP 257
Query: 661 SSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDG 720
++ A A A AP P P PA L +P A P T++ + P+
Sbjct: 258 PAAPAPAAPAA-------APPPPPPAPA--TLARPPGHPA---GPPTAAPAVPPPAAAQN 305
Query: 721 LGDL-LMPTMAPA-GQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKG 778
G P APA G PA VS P A AA+ A G +S + + T G
Sbjct: 306 GGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASG 365
Query: 779 DLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGA 838
PA+ +A + +QGA+P ++VPP A G P
Sbjct: 366 ----------------------PASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKG 403
Query: 839 GFG--------MPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSP 880
G P A T P + A + +PP + QL P
Sbjct: 404 AAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPP 453
Score = 66.2 bits (160), Expect = 1e-10
Identities = 125/498 (25%), Positives = 169/498 (33%), Gaps = 94/498 (18%)
Query: 259 IDKGDIPDLTQAPSSLMETLEQHLNTLEGKKP----------GNNEGSGAPSPLSKSSPA 308
+D+ + DL + S + H + L + P GN+ SG+P+ + + PA
Sbjct: 17 VDEKVVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPA 76
Query: 309 TTVT-SPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAP 367
+P + P PP A P PS + G A AA
Sbjct: 77 APAEGAPGAAP------EPPPAGRARPGGGGPQRPGPPSP-----RRPLVPAGPAPPAAK 125
Query: 368 APPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTT 427
PPP G A + + VP+ A ++ P P P A A +A A
Sbjct: 126 LRPPPEGSA------------GSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPG 173
Query: 428 TTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSA 487
G PG P G A T AA L++ + AP+
Sbjct: 174 P------------GPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNS---HHAAAPAVSLV 218
Query: 488 EAAPELDLFAMKPPETSVPVVTP--TASTAPPVPATAPSP--APAVAAAAAATTAATAAA 543
P L KP + TP + APP PA APSP APA AA AAA A
Sbjct: 219 NNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPA-APSPPAAPAPAAPAAAPPPPPPAP 277
Query: 544 TTTTTTSA--ATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGA 601
T A TA PA+ ++ AAP P A + P G
Sbjct: 278 ATLARPPGHPAGPPTAAPAVPP-PAAAQNGGSAGAAPAPAPA-----------AGGPAGV 325
Query: 602 SPVPESSLTADLLSVDAFAAPSPATTA-SPAKVDSSGVIDLFGDAFGSSASEPQPASQAA 660
S P A AAP+P A SP +V A+ P + AA
Sbjct: 326 SGQPGPGAAA--------AAPAPGVKAESPKRV--------------VQAAPPAAQTLAA 363
Query: 661 SS-SSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFD 719
S +S +A ++ G PSP+ V P + A G T S S +
Sbjct: 364 SGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAV--TQSLSRTPTATTS 421
Query: 720 GLGDLLMPTMAPAGQPAP 737
G+ L PT+ P P
Sbjct: 422 GIRATLTPTVLAPRLPQP 439
Score = 50.8 bits (120), Expect = 6e-06
Identities = 103/384 (26%), Positives = 133/384 (34%), Gaps = 80/384 (20%)
Query: 527 PAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSI 586
P V AAAA A + S A A A PA E P AAP+P A
Sbjct: 48 PEVRAAAAG-----ALGNHVVSGSPAGAAGAGPAAPA-----EGAP--GAAPEPPPAGR- 94
Query: 587 DLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAF 646
+ P + P P L V A AP A P + + + A
Sbjct: 95 ---ARPGGGGPQRPGPPSPRRPL------VPAGPAPPAAKLRPPPEGSAGSCAPVPAAAA 145
Query: 647 GSSASEPQPASQAASSSSASADLLAGFG---GSFMAPSPSPVTPAQNNLLQP-NFEAAFG 702
++ EP PA A + A+ AG G G P P P PA Q N AA
Sbjct: 146 VAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALL 205
Query: 703 TTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLA 762
+ ++ + S+ + L+P PA P V PP AA A + +
Sbjct: 206 NSHHAAAPAV---SLVNNGPAALLPLPKPAA-PGTVIQTPPFVGAAAPPAPAAPSPPA-- 259
Query: 763 SLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTS 822
A A P APAT + PP P A PPT+
Sbjct: 260 ---------------------APAPAAPAAAPPPPPPAPATLAR--PPGHP---AGPPTA 293
Query: 823 S--VPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSP 880
+ VPP A A + G GA PA G + QP P AAA +P
Sbjct: 294 APAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQP---------GPGAAAA------AP 338
Query: 881 SPTPASQSPKK-----PPAKDPLA 899
+P ++SPK+ PPA LA
Sbjct: 339 APGVKAESPKRVVQAAPPAAQTLA 362
Score = 33.9 bits (76), Expect = 0.71
Identities = 76/301 (25%), Positives = 96/301 (31%), Gaps = 46/301 (15%)
Query: 610 TADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADL 669
T ++ + A A + + SPA +G A G+ A EP PA +A
Sbjct: 47 TPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGA-APEPPPAGRARP-------- 97
Query: 670 LAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTM 729
G GG PSP P P AA P S+ S P +
Sbjct: 98 --GGGGPQRPGPPSPRRPLVP--AGPAPPAAKLRPPPEGSAGSCAP---------VPAAA 144
Query: 730 APAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKL 789
A A P P P PA A+ A + G G G Q G L
Sbjct: 145 AVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAAL 204
Query: 790 TGGANWQPKVAPATWSAGVPPSA--PLQGAVPPTSSV--PPVAG-----APSVGQPGAGF 840
N APA P+A PL P + + PP G AP+ P A
Sbjct: 205 L---NSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAP 261
Query: 841 GMPPAGTGMPMMPQQPVMFAQP---MMRPPFGAAAVP---------GTQLSPSPTPASQS 888
P P P A+P PP A AVP +P+P PA+
Sbjct: 262 APAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGG 321
Query: 889 P 889
P
Sbjct: 322 P 322
Score = 33.1 bits (74), Expect = 1.2
Identities = 50/191 (26%), Positives = 63/191 (32%), Gaps = 23/191 (12%)
Query: 717 VFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTK 776
V D +G L A A ++ P AA+ ALG+ + S S G G
Sbjct: 22 VSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSG--SPAGAAGAGPAAPA 79
Query: 777 KG-----DLQWNAGEKKLTGGANWQPKVA----PATWSAGVPPSAPLQGAVPPTSSVPPV 827
+G AG + GG +P P + PP+A L+ PP S
Sbjct: 80 EGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRP--PPEGSAGSC 137
Query: 828 AGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQ 887
A P+ AG PAG P P A P PG P P P
Sbjct: 138 APVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGP----------GPGPGPGPGPGPGPG 187
Query: 888 SPKKPPAKDPL 898
P P A L
Sbjct: 188 KPAGPGAAQTL 198
Score = 30.4 bits (67), Expect = 7.8
Identities = 79/414 (19%), Positives = 123/414 (29%), Gaps = 69/414 (16%)
Query: 289 KPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFAT------------ASA 336
+PG + AP+P K+ V A+T+ S P A+ + A
Sbjct: 328 QPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPA 387
Query: 337 AVP-----VSTSKPS------SDLLDLQPDFSSGGAAAAAAPA------PPPPAGGATAW 379
AVP T P + L P ++ G A P P PP
Sbjct: 388 AVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQ 447
Query: 380 ------GDLLGEDSLAALSSVPSEA----------QISDPFAPEPTPPTTTAEIATASAS 423
G +L L +P +A Q AP P PT+ + ++
Sbjct: 448 NFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQ 507
Query: 424 ASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPS 483
A T + + A P+A+ L G P
Sbjct: 508 APGTPIIARQVTPTTIIKQVSQAQTTVQPSAT---------------LQRSPGVQPQLVL 552
Query: 484 EGSAEAAPELDLFAMK--PPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATA 541
G+A+ A A++ P+ +VP T T+S A ++ ++
Sbjct: 553 GGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQ 612
Query: 542 AATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGA 601
+ T ++ E+ ++P+P P + S P
Sbjct: 613 STETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLK-------RSLPALR 665
Query: 602 SPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQP 655
P+S+ S ATTA A V SS V G + S QP
Sbjct: 666 QLTPDSAAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQP 719
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 75.1 bits (183), Expect = 3e-13
Identities = 151/618 (24%), Positives = 239/618 (38%), Gaps = 96/618 (15%)
Query: 295 GSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSS----DLL 350
G P P++ +S A+T ++T DTS A+ A P+ + SS D
Sbjct: 3468 GHATPLPVTDTSSAST---GDTTRLPVTDTSS-----ASTGQATPLPVTSLSSVSTGDTT 3519
Query: 351 DLQPDFSSGGAAAAAAPAPPPPAGGATAWGD---LLGEDSLAALSSVPSEAQISDPFAPE 407
L +S + A P P A+ GD L D+ +A + + ++ P +
Sbjct: 3520 PLLVTDASSVSTGHATPLPVTDTSSAST-GDTTRLPVTDTSSASTGQATPLPVTIPSSSS 3578
Query: 408 -----PTPPTTTAEIATA--------SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAA 454
P P T+T+ ++T S S+++T VT + A+P A
Sbjct: 3579 SGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDA 3638
Query: 455 SEGAAAPATPTPVAAALDACSGN-------DPFAPSEGSAEAAPELDLFAMKPPETSVPV 507
S + ATP PV A A +G+ D + S G A P L ++ +T+
Sbjct: 3639 SSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLP 3698
Query: 508 VTPTAST----APPVPATAPS--------PAPAVAAAAAATTAATAAATTTTTTSAATAT 555
VT +S A P+P T PS P P + ++A+T AT T ++++ T
Sbjct: 3699 VTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDT 3758
Query: 556 TAPPALDIFGDLFESTPEVAAAPKPD-AAPSID----LFSTDAFSSPPQGASPVPESSLT 610
T P D ST P D ++ S D L TD S+ A+P+P +S +
Sbjct: 3759 TPLPVTDTSS---ASTRHATPLPVTDTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTS 3815
Query: 611 ADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSA-SEPQPASQAASSSSASADL 669
+ + P P T S + + + + S+ + P P + +S S+ A
Sbjct: 3816 S---ASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATP 3872
Query: 670 LAGFGGSFMA---PSPSPVTPAQNNLLQPNFEAAFGTTP----STSSSSSFD-------- 714
L S ++ +P PVT P+ + TP STSS+S+ D
Sbjct: 3873 LPVTSTSSVSTGHATPLPVT-------SPSSASTGHATPVPVTSTSSASTGDTTPLPVTN 3925
Query: 715 -PSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGT 773
S+ G L T + S +P + A +AS + L + S V +G
Sbjct: 3926 ASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSLSSVS----TGD 3981
Query: 774 TTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAG----VPPSAPLQGAVPPTSSVPPVAG 829
TT L TG A P + ++ S G +P + P + T+S+ PV
Sbjct: 3982 TT---PLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSL-PVTD 4037
Query: 830 APSVGQPGAGFGMPPAGT 847
A SV G G +P T
Sbjct: 4038 ASSV-STGHGTPLPVTST 4054
Score = 73.2 bits (178), Expect = 1e-12
Identities = 139/610 (22%), Positives = 220/610 (36%), Gaps = 85/610 (13%)
Query: 295 GSGAPSPLSKSSPATT-------VTSPNSTPAKTIDTSP-PVDLFATASA--AVPVSTSK 344
G P P++ +S A+T VTS +S T DT+P PV ++AS A P+ +
Sbjct: 3660 GDTTPLPVTDTSSASTGQATPLPVTSLSSV--STGDTTPLPVTDASSASTGHATPLPVTI 3717
Query: 345 PSS----DLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQI 400
PSS D + L S + A P P + G S + + P
Sbjct: 3718 PSSVSTGDTMPLPVTSPSSASTGHATPLP------------VTGLSSASTGDTTPLPVTD 3765
Query: 401 SDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAA 460
+ + P + ++AS +T VT V++ A+P + S +
Sbjct: 3766 TSSASTRHATPLPVTDTSSASTDDTTRLPVTDVSS-----ASTGHATPLPVTSTSSASTG 3820
Query: 461 PATPTPVAAALDACSGNDPFAP-------SEGSAEAAPELDLFAMKPPETSVPVVTPTAS 513
TP PV +G+ P S G A P D ++ + VT T+S
Sbjct: 3821 DTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSS 3880
Query: 514 T----APPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFE 569
A P+P T+PS +A+T T+T+SA+T T P + L
Sbjct: 3881 VSTGHATPLPVTSPS---------SASTGHATPVPVTSTSSASTGDTTPLPVTNASSLST 3931
Query: 570 STPEVAAAPKPDAAPSID---LFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPAT 626
P +A D L TDA S+ A+P+P +SL++ P P T
Sbjct: 3932 GHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSLSS---VSTGDTTPLPVT 3988
Query: 627 TASPAKVDSSGVIDLFG-DAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAP---SP 682
S A + + + + + + P P + +S+SS L S ++ +P
Sbjct: 3989 DTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTP 4048
Query: 683 SPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPV---S 739
PVT + T S S+ + V D + A G P+ S
Sbjct: 4049 LPVTSTSSASTGDTTPLPVTDTSSASTGHATPLPVTD-------TSSASTGHATPLPVTS 4101
Query: 740 MVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKV 799
+ S A A+ S +S S L + L+ + G + T
Sbjct: 4102 LSSVSTGHATPLAVSSATSASTVSSDSPLKMETPGMTTPSLKTDGGRRTATS-------- 4153
Query: 800 APATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMF 859
P T S + + P A+ S+ P+ P G +G AG G ++ V F
Sbjct: 4154 PPPTTSQTIISTIP-STAMHTRSTAAPIPILPERGVSLFPYG---AGAGDLEFVRRTVDF 4209
Query: 860 AQPMMRPPFG 869
P+ +P G
Sbjct: 4210 TSPLFKPATG 4219
Score = 67.8 bits (164), Expect = 4e-11
Identities = 130/566 (22%), Positives = 205/566 (36%), Gaps = 99/566 (17%)
Query: 251 LKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGN-NEGSGAPSPLSKSSPAT 309
L V + + G L +S + T H +L P + + G P P++ +S +
Sbjct: 2673 LPVTDASSVSTGHATSLPVTDASSVFT--GHATSLPVTIPSSASSGHTTPLPVTDASSVS 2730
Query: 310 T--VTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKP----------SSDLLDLQPDFS 357
T TS T A ++ T L T +++V + P + D L +
Sbjct: 2731 TGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDT 2790
Query: 358 SGGAAAAAAPAPPPPAGGATAWGD---LLGEDSLAALSSVPSEAQISDPFAPEPTPPTTT 414
S + A P P + GD L D+ +A + + ++D + T
Sbjct: 2791 SSASTGQATPLPVTSLSSVST-GDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPL 2849
Query: 415 AEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAP------------- 461
+ T+SAS T + G A + + + S G A P
Sbjct: 2850 PDTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGH 2909
Query: 462 ATPTPVAAALDACSGN-------DPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTAST 514
ATP PV A +G+ P + S G A P D + + VT +S
Sbjct: 2910 ATPLPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSV 2969
Query: 515 AP----PVPATAPS--------PAPAVAAAAAATTAATAAATTTTTTSAATATTAP-PAL 561
+ P+P T+PS P P ++A+T ATA T+T+ SA+T T P P
Sbjct: 2970 STGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTS-SASTGDTTPLPVT 3028
Query: 562 DI-FGDLFESTPEVAAA----------PKPDAAPS-------IDLFSTDAFSSPPQGASP 603
D ++TP + P P +PS L TDA S+ A+P
Sbjct: 3029 DTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATP 3088
Query: 604 VPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSS 663
+P +SL++ P P T+ S A G A ++ AS ++S
Sbjct: 3089 LPVTSLSS---VSTGDTTPLPVTSPSSAST---------GHATSLPVTDTSSASTGDTTS 3136
Query: 664 SASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGD 723
D + + G + PVT ++ + TTP + +S SV G
Sbjct: 3137 LPVTDTSSAYTGD---TTSLPVTDTSSS-------STGDTTPLLVTETS---SVSTGHAT 3183
Query: 724 LLMPT---MAPAGQPAPVSMVPPSPA 746
L+ T A G P+ + PS A
Sbjct: 3184 PLLVTDASSASTGHATPLHVTSPSSA 3209
Score = 65.5 bits (158), Expect = 2e-10
Identities = 109/500 (21%), Positives = 182/500 (36%), Gaps = 72/500 (14%)
Query: 292 NNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLL- 350
++ +G +PL + ++V++ ++TP D S A+ A P+ + PSS
Sbjct: 3159 SSSSTGDTTPLLVTE-TSSVSTGHATPLLVTDASS-----ASTGHATPLHVTSPSSASTG 3212
Query: 351 DLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTP 410
D P + ++ + A P P G ++ G+ + ++ + S + P P
Sbjct: 3213 DTTPVPVTDTSSVSTGHATPLPVTGLSSAST--GDTTRLPVTDISS----ASTGQATPLP 3266
Query: 411 PTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAA 470
T T+ ++T T+ ++ + A+P + S + ATP PV +
Sbjct: 3267 VTNTSSVSTGDTMPLPVTSPSSASTG--------HATPLPVTSTSSASTGHATPVPVTST 3318
Query: 471 LDACSGNDPFAP--SEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPA 528
A +G+ P SA L P S TP T P +T +
Sbjct: 3319 SSASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLP 3378
Query: 529 VAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDL 588
V A++A+T T T+S +T P + + ST + P
Sbjct: 3379 VTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSV--STGDTTPLP---------- 3426
Query: 589 FSTDAFSSPPQGASPVPESSL-------TADLLSVDA------FAAPSPATTASPAKVDS 635
TDA S+ A+P+P +SL T LL DA A P P T S A
Sbjct: 3427 -VTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGD 3485
Query: 636 SGVIDLFGDAFGSSA-SEPQPASQAASSSSASADLLAGFGGSFMA---PSPSPVTPAQNN 691
+ + + + S+ + P P + +S S+ L S ++ +P PVT +
Sbjct: 3486 TTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSA 3545
Query: 692 L--------LQPNFEAAFG-------TTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPA 736
+ A+ G T PS+SSS P + + P +
Sbjct: 3546 STGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTS 3605
Query: 737 PVSM----VPPSPAMAASKA 752
P S V P P + S A
Sbjct: 3606 PSSASTGHVTPLPVTSTSSA 3625
Score = 64.7 bits (156), Expect = 4e-10
Identities = 110/483 (22%), Positives = 181/483 (37%), Gaps = 52/483 (10%)
Query: 295 GSGAPSPLSKSSPATT--VTSPNSTPAKTIDT--SPPVDLFATASAAVPVSTSKPSSDLL 350
G P P++ +S A+T TS T ++ T + P+ + T+SA+ +TS P +D
Sbjct: 1084 GDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTDTS 1143
Query: 351 DLQ-----PDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFA 405
+ P + ++A+ A P P T+ + D+ + PS A
Sbjct: 1144 SVSTGHTTPLHVTDASSASTGQATPLPV---TSLSSVSTGDTTPLPVTSPSSASTGHA-- 1198
Query: 406 PEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPT 465
P T T+ +T A+ T ++V+ D + P P+A+ + TP
Sbjct: 1199 -TPLLVTDTSSASTGHATPLPVTDASSVST------DHATSLPVTIPSAA--STGHTTPL 1249
Query: 466 PVAAALDACSGNDP--FAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAP 523
PV A +G S L S VTP T+P +T
Sbjct: 1250 PVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGH 1309
Query: 524 SPAPAVAAAAAATTAATAAATTTTTTSAATATTAP-PALDIFG-DLFESTP-EVAAAPKP 580
+ V + ++A+T T T+ +SA+T T P P D +TP V A
Sbjct: 1310 ATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSA 1369
Query: 581 DAAPSIDLFSTDAFSSPPQGASPVPESS------------LTADLLSVD-AFAAPSPATT 627
+ L T S +P+P +S L D S A P P T
Sbjct: 1370 STGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTD 1429
Query: 628 ASPAKVDSSGVIDL-FGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMA---PSPS 683
AS D + + + A + + P P + +S+S+ A L S ++ +P
Sbjct: 1430 ASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPL 1489
Query: 684 PVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPP 743
PVT + ++ + T+PS++S+ P L + A G P+ + P
Sbjct: 1490 PVT-STSSASTGHVTPLHVTSPSSASTGHATPLPVTSL------SSASTGDTMPLPVTSP 1542
Query: 744 SPA 746
S A
Sbjct: 1543 SSA 1545
Score = 64.3 bits (155), Expect = 5e-10
Identities = 125/486 (25%), Positives = 180/486 (37%), Gaps = 106/486 (21%)
Query: 295 GSGAPSPLSKSSPATT-------VTSPNSTPAKTIDTSP-PVDLFATASA---------- 336
G P P++ +S A+T VTS +S T DT+P PV ++AS
Sbjct: 2028 GDTTPLPVTDTSSASTGQDTPLPVTSLSSV--STGDTTPLPVTSPSSASTGHATPLLVTD 2085
Query: 337 AVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPS 396
A VST +S L+ S+G A A T L D+ + PS
Sbjct: 2086 ASSVSTGHATSLLVTDASSVSTGHATALHV----------TDASSLSTGDTTPLPVTSPS 2135
Query: 397 EAQISDPFAPEPTPPTTTAEIATASA-SASTTTTVTAVTAEVDLFG--DAFAASPGEAPA 453
A D P P T T+ ++T A S T T +A T D +AS G A
Sbjct: 2136 SASTGDT---TPLPVTDTSSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHATP 2192
Query: 454 -----ASEGAAAPATPTPVAAALDACSGN-------DPFAPSEGSAEAAPELDLFAMKPP 501
S + ATP PV + A +G+ D + S G A P L +
Sbjct: 2193 LPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTG 2252
Query: 502 ETSVPVVTPTASTAP--------------------PVPATAPSPAPAVAAAAAATTAATA 541
+T+ VT +S + P+P T+PS A A T A++
Sbjct: 2253 DTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASS 2312
Query: 542 AAT-------TTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAF 594
A+T T+ +SA+T T P L ++P ++A A P L TDA
Sbjct: 2313 ASTGHATPLPVTSLSSASTGDTTP--------LPVTSP--SSASTGHATP---LHVTDAS 2359
Query: 595 SSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQ 654
S +P+P +T+ + P P T AS A GD + P
Sbjct: 2360 SVSTGDTTPLP---VTSSSSASSGHTTPLPVTDASSAST---------GD------TTPL 2401
Query: 655 PASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFD 714
P + +S+S+ A L G S + + P N A STSS+S+ D
Sbjct: 2402 PVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGD 2461
Query: 715 PSVFDG 720
+ G
Sbjct: 2462 TTPLPG 2467
Score = 63.9 bits (154), Expect = 6e-10
Identities = 141/630 (22%), Positives = 227/630 (36%), Gaps = 73/630 (11%)
Query: 251 LKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGN-NEGSGAPSPLSKSSPAT 309
L V + + GD L +S T H+ L P + + G P P++ S A+
Sbjct: 1265 LLVTDTSSVSTGDTTPLPVTSTSSAST--GHVTPLHVTSPSSASTGHATPLPVTSLSSAS 1322
Query: 310 T-------VTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAA 362
T VTSP+S A T DT+P L T +++V + P L +S +
Sbjct: 1323 TGDTMPLPVTSPSS--ASTGDTTP---LPVTDASSVSTGHTTP------LHVTDASSAST 1371
Query: 363 AAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASA 422
A P P T+ + D+ + PS A P T T+ +T A
Sbjct: 1372 GQATPLP------VTSLSSVSTGDTTPLPVTSPSSASTGHA---TPLLVTDTSSASTGHA 1422
Query: 423 SASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDP--F 480
+ T ++V+ D + P P+A+ + TP PV A +G
Sbjct: 1423 TPLPVTDASSVST------DHATSLPVTIPSAA--STGHTTPLPVTDTSSASTGQATSLL 1474
Query: 481 APSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAAT 540
S L S VTP T+P +T + V + ++A+T T
Sbjct: 1475 VTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDT 1534
Query: 541 AAATTTTTTSAATATTAP-PALDIFG-DLFESTPEVAAAP-KPDAAPSIDLFSTDAFSSP 597
T+ +SA+T T P P D +TP +P + L TD S+
Sbjct: 1535 MPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSAS 1594
Query: 598 PQGASPVPESS-------LTADLLSVDAFAA------PSPATTASPAKVDSSGVIDLFGD 644
+P+P +S T L D +A P P T AS + + +
Sbjct: 1595 KGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSP 1654
Query: 645 AFGSSA-SEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGT 703
+ S+ + P P + +S+S+ A L G S + P + +A
Sbjct: 1655 SSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSASTGQATPLP 1714
Query: 704 TPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMA--ASKALGSDLDSSL 761
S SS S+ D + + P+ A G +P+ + S A A+ +D S
Sbjct: 1715 VTSLSSVSTGDTTPL----PVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVS 1770
Query: 762 ASLVGNLGISGTTTKKGD----LQWNAGEKKLTGGANWQPKVAPATWSAG----VPPSAP 813
+ L ++G ++ D L TG A P +P++ S G +P +
Sbjct: 1771 TAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDA 1830
Query: 814 LQGAVPPTSSVPPVAGAPSVGQPGAGFGMP 843
+ T+S+P PS G +P
Sbjct: 1831 SSASTGDTTSLP--VTIPSSASSGHTTSLP 1858
Score = 63.9 bits (154), Expect = 6e-10
Identities = 120/521 (23%), Positives = 187/521 (35%), Gaps = 61/521 (11%)
Query: 295 GSGAPSPLSKSSPATT--VTSPNSTPAKTIDTSPPVDLFATASAAV------PVSTSKPS 346
G P P++ S A+T T T A ++ T L T+ ++V P+ + PS
Sbjct: 2236 GQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPS 2295
Query: 347 S----DLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEA---Q 399
S L +S + A P P A+ GD + S+ A
Sbjct: 2296 SASTGHATPLHVTDASSASTGHATPLPVTSLSSAST-GDTTPLPVTSPSSASTGHATPLH 2354
Query: 400 ISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPA-----A 454
++D + T TT + ++S+++S TT VT DA +AS G+
Sbjct: 2355 VTDASSVS-TGDTTPLPVTSSSSASSGHTTPLPVT-------DASSASTGDTTPLPVTDT 2406
Query: 455 SEGAAAPATPTPVAAALDACSGNDPFAP--SEGSAEAAPELDLFAMKPPETSVPVVTPTA 512
S + AT PV A +G+ P + SA L S TP
Sbjct: 2407 SSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLP 2466
Query: 513 STAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTP 572
T +T + V A++ +T T T+ +SA+T T P L + ST
Sbjct: 2467 GTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTP--LPVTDTPSASTG 2524
Query: 573 EVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSL--TADLLSVDAFAAPSPATTASP 630
+ P +A+ +T + P AS +SL T + A P P T+ S
Sbjct: 2525 DTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTSTSS 2584
Query: 631 AKVDSSG---VIDLFGDAFG----------SSASE----PQPASQAASSSSASADLL--- 670
A + V D + + G SSAS P P + +S+S+ A L
Sbjct: 2585 ASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVT 2644
Query: 671 ------AGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDL 724
G SPS + L ++ T +TS + SVF G
Sbjct: 2645 NTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHATS 2704
Query: 725 LMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLV 765
L T+ + + +P + A + S + L + AS V
Sbjct: 2705 LPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSV 2745
Score = 63.2 bits (152), Expect = 1e-09
Identities = 128/539 (23%), Positives = 206/539 (38%), Gaps = 118/539 (21%)
Query: 251 LKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGN-NEGSGAPSPLSKSSPAT 309
L V + + GD L +S T H+ L P + + G P P++ S A+
Sbjct: 1473 LLVTDTSSVSTGDTTPLPVTSTSSAST--GHVTPLHVTSPSSASTGHATPLPVTSLSSAS 1530
Query: 310 T-------VTSPNSTPAKTIDTSP---------------PVDLFATASAAVPVSTSKPSS 347
T VTSP+S A T DT+P P+ + + +SA+ +T P +
Sbjct: 1531 TGDTMPLPVTSPSS--ASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVT 1588
Query: 348 DLL-----DLQP-DFSSGGAAAAAAPAPPPPAGGATA-WGDL--LGEDSLAALSS----- 393
D D P +S +A+ P P ++A GD L + ++LS+
Sbjct: 1589 DTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATP 1648
Query: 394 --VPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDL---FGDAFAASP 448
V S + S A P P T+T+ +T A+ T +++ T + D +AS
Sbjct: 1649 LHVTSPSSASTGHAT-PLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSAST 1707
Query: 449 GEAP-----AASEGAAAPATPTPVAAALDACSGN-------DPFAPSEGSAEAAPELDLF 496
G+A + S + TP PV + A +G+ D + S G A P D
Sbjct: 1708 GQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTS 1767
Query: 497 AMKPPE-----------------TSVPVV-TPTAST--APPVPATAPS--------PAPA 528
++ T +PV +AST A P+P T+PS P P
Sbjct: 1768 SVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPV 1827
Query: 529 VAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDL 588
A++A+T T+ T +++++ TT+ P D A + L
Sbjct: 1828 TDASSASTGDTTSLPVTIPSSASSGHTTSLPVTD--------------ASSVSTGHATSL 1873
Query: 589 FSTDAFSSPPQGASPVP----ESSLTADLLSVDAFAAPS---------PATTASPAKVDS 635
TDA S +P+P S+ T D + A S P T+ S A
Sbjct: 1874 LVTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGD 1933
Query: 636 SGVIDLFGDAFGSSA-SEPQPASQAASSSSASADLLAGFGGSFMA---PSPSPVTPAQN 690
+ + + + SS + P P + A+S + A L S ++ +P PVT A +
Sbjct: 1934 TTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASS 1992
Score = 57.4 bits (137), Expect = 6e-08
Identities = 100/469 (21%), Positives = 170/469 (36%), Gaps = 63/469 (13%)
Query: 308 ATTVTSPNSTPAKTIDTSP-------PVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGG 360
A++V++ ++TP DT+ P+ + +S + +TS P + L S+G
Sbjct: 1878 ASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSA----STGD 1933
Query: 361 AAAAAAPAPPPPAGGATAWGDLLGEDSLAA--LSSVP-SEAQISDPFAPEPTPPTTTAEI 417
+P + G T + S+ +S+P ++A P P T + +
Sbjct: 1934 TTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSV 1993
Query: 418 ATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGN 477
+T A+ T ++V+ A+P + S + TP PV A +G
Sbjct: 1994 STGHATPLPVTDTSSVSTG--------QATPLPVTSLSSASTGDTTPLPVTDTSSASTGQ 2045
Query: 478 DPFAP--SEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAA 535
D P S S L P S TP T +T + + V A++
Sbjct: 2046 DTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSV 2105
Query: 536 TTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDA-------APSIDL 588
+T A T +S +T T P L + ST + P D A S+ +
Sbjct: 2106 STGHATALHVTDASSLSTGDTTP--LPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPV 2163
Query: 589 FSTDAFSSPPQGASPVPESS-----------LTADLLSVDAFAAPSPATTASPAKVDSSG 637
T + S+ + PV ++S +T + A P P T+ S A
Sbjct: 2164 TDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSAST-GHA 2222
Query: 638 VIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNF 697
+ L D +S + P + SS+++ D +P PVT A + +
Sbjct: 2223 IPLLVTDTSSASTGQATPLPVTSLSSASTGD-----------TTPLPVTDASS--VSTGH 2269
Query: 698 EAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPA 746
+ T S SS S+ D + + P+ A G P+ + S A
Sbjct: 2270 ATSLPVT-SLSSVSTGDTTPL----PVTSPSSASTGHATPLHVTDASSA 2313
Score = 55.8 bits (133), Expect = 2e-07
Identities = 100/425 (23%), Positives = 169/425 (39%), Gaps = 49/425 (11%)
Query: 292 NNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLD 351
++ +G +PL +SP++ T ++TP D S V T V S+S S
Sbjct: 2327 SSASTGDTTPLPVTSPSSASTG-HATPLHVTDASS-VSTGDTTPLPVTSSSSASSGHTTP 2384
Query: 352 LQPDFSSGGAAAAAAPAPPPPAGGA-TAWGDLLGEDSLAALSS-------VPSEAQISDP 403
L +S + P P A T L L++ S+ V + + S
Sbjct: 2385 LPVTDASSASTGDTTPLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSASTG 2444
Query: 404 FAPEPTPPTTTAEIATASAS---ASTTTTVTAVTAEVDLFGDAFAASPGEA---PAASEG 457
A P P T+T+ +T + + T++V+ L DA + S G+ P S
Sbjct: 2445 HAT-PLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPS 2503
Query: 458 AAAPA--TPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTA 515
+A+ TP PV A +G+ P ++ + TS+ V +P++++
Sbjct: 2504 SASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTR--------HATSLHVTSPSSAS- 2554
Query: 516 PPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAP-PALDIF-GDLFESTP- 572
T + + V +AA+T T+T+SA+T T P P D + ++TP
Sbjct: 2555 -----TGHATSLPVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPL 2609
Query: 573 ---EVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVP---ESSLTADLLSVDAFAAPSPAT 626
+ ++A D P L TD S+ A+P+P SS++ + +PS A+
Sbjct: 2610 PVTDTSSASTGDTTP---LPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSAS 2666
Query: 627 TASPAKVDSSGVIDLFGDAFGSSASEP-QPASQAASSSSASADLLAGFGGSFMAPSPSPV 685
T + V D + G + S P AS + + S + S +P PV
Sbjct: 2667 TGHTTPLP---VTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPV 2723
Query: 686 TPAQN 690
T A +
Sbjct: 2724 TDASS 2728
Score = 52.8 bits (125), Expect = 1e-06
Identities = 97/433 (22%), Positives = 154/433 (35%), Gaps = 66/433 (15%)
Query: 305 SSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKP----------SSDLLDLQP 354
S +T SP+S P K I T+ F T + +T +P S ++ L
Sbjct: 431 SDTLSTALSPSSLPPK-ISTA-----FHTQQSEGAETTGRPHERSSFSPGVSQEIFTLHE 484
Query: 355 ------DFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEP 408
FSS G + P + GA A + G S ++P EP
Sbjct: 485 TTTWPSSFSSKGHTTWSQTELPSTSTGA-ATRLVTGNPSTGTAGTIPRVPSKVSAIG-EP 542
Query: 409 TPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVA 468
PTT + +T + T T E G+A +SP + A
Sbjct: 543 GEPTTYSSHSTTLPKTTGAGAQTQWTQETGTTGEALLSSPSYSVTQMIKTAT-------- 594
Query: 469 AALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPA 528
S ++P LD TS + T ++ + +T+ SP +
Sbjct: 595 -----------------SPSSSPMLD------RHTSQQITTAPSTNHSTIHSTSTSPQES 631
Query: 529 VAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDL 588
A + T A + TT + + T + G F ++ + P AP+I
Sbjct: 632 PAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISA 691
Query: 589 FSTDAFSSPPQG---ASPVPESSLTADLLSVDAFAAPSPATTASP--AKVDSSGVIDLFG 643
+T F+ P G + P ++L A S DA PS T+ S A ++ V+ G
Sbjct: 692 ATT--FAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPG 749
Query: 644 DAFG---SSASEPQPASQAASSSSASADLLAGFGGSFMA-PSPSPVTPAQNNLLQPNFEA 699
G S+++ P + AA + + A+ G + + P+ S P+
Sbjct: 750 GPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSG 809
Query: 700 AFGTTPSTSSSSS 712
A GTTPS S S
Sbjct: 810 ASGTTPSGSEGIS 822
Score = 50.4 bits (119), Expect = 7e-06
Identities = 106/452 (23%), Positives = 159/452 (35%), Gaps = 66/452 (14%)
Query: 268 TQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPP 327
TQAP++ ++ + G G + LSK+ T S STP P
Sbjct: 706 TQAPTTALQAAPSSHDATLGPSGGTS--------LSKTGALTLANSVVSTPGG------P 751
Query: 328 VDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDS 387
+ +ASA STS ++ + S A+ + P +G T S
Sbjct: 752 EGQWTSASA----STSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSS 807
Query: 388 LAALSSVPSEAQ-ISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAA 446
A + PS ++ IS T TT + S + TT + T + + G A
Sbjct: 808 SGASGTTPSGSEGIS-------TSGETTRFSSNPSRDSHTTQSTTELLSASASHG-AIPV 859
Query: 447 SPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETS-- 504
S G A + G P T + + A + P +PS E A + + TS
Sbjct: 860 STGMASSIVPGTFHP-TLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRG 918
Query: 505 ------VPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAP 558
T T ST PP P + S T + + + T TT + AT P
Sbjct: 919 SDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLP 978
Query: 559 PALDIFGDLFESTP----------EVAAAPKPDAAPS-------IDLFSTDAFSSPPQGA 601
+TP A P P +PS L TD S
Sbjct: 979 VTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHV 1038
Query: 602 SPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSAS----EPQPAS 657
+P+P +S ++ + + P P T S A S+G + SSAS P P +
Sbjct: 1039 TPLPVTSFSS---ASTGDSTPLPVTDTSSA---STGHVTPLPVTSLSSASTGDTTPLPVT 1092
Query: 658 QAASSSSASADLLAGFGGSFMA---PSPSPVT 686
+S+S+ A L S ++ +P PVT
Sbjct: 1093 DTSSASTGHATSLPVTDTSSVSTGHTTPLPVT 1124
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 74.7 bits (182), Expect = 4e-13
Identities = 147/592 (24%), Positives = 203/592 (34%), Gaps = 134/592 (22%)
Query: 353 QPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPT 412
+P + G A AAP PP PA +W + LS S P P
Sbjct: 535 RPPTTGGSEGAGAAPCPPNPAN---SW--------VPGLSPGGSRRP--------PRSPE 575
Query: 413 TTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEA-PAASEGAAAPATP-TPVAAA 470
T ++ +S S T T+ L G ASPG+A P E + +P V+++
Sbjct: 576 RTLSPSSGYSSQSGTPTLPPK----GLAGPP--ASPGKAQPPKPERVTSLRSPGASVSSS 629
Query: 471 LDA-CSGNDPFAPSEGSAEA--APELDLFAMKP-PETSVPVVTPTASTAPPVPATAPSPA 526
L + CS + APS+ S P D F + P P+ P P + P PA A
Sbjct: 630 LTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAA 689
Query: 527 PAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSI 586
PAV +TT A+ + T T+ +P P P P P +
Sbjct: 690 PAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEV 749
Query: 587 DLFSTDAFSS------PPQGASPVPESSLTADLLSVDAFAAPSPA--TTASPAKVDSSGV 638
+ + A + P P P + DL D F P A + ASP
Sbjct: 750 VVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMAD-FPPPEEAFFSVASP-------- 800
Query: 639 IDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFE 698
+ G S S +S AASSSSA+A + G P+P PA + P
Sbjct: 801 -----EPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASS---APGHV 852
Query: 699 AAFGTTPSTSSSSSFDPSVFDGLGDLLMPTM----------APAGQPAPVSMVP------ 742
A S P D L+ P++ AP G P P ++ P
Sbjct: 853 AKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTP-ALGPSAPQKP 911
Query: 743 --------PSPAMAASKALGSDLDSSLASLVGNLGISG---------------TTTKKGD 779
SP A S L + + SL + G+S +
Sbjct: 912 LRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTAS 971
Query: 780 LQWNAGEKKLTGGANWQPKVAPATW--------------SAGVPPSAPLQGAVPPTSSVP 825
++ G +KL + V+P T S PP AP + P P
Sbjct: 972 FIFSKGSRKL----QLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAP----P 1023
Query: 826 PVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQ 877
PVA PSVG P PPA P A+P+ PP +P TQ
Sbjct: 1024 PVARKPSVGVP------PPASPSYPR--------AEPLTAPP--TNGLPHTQ 1059
Score = 57.0 bits (136), Expect = 8e-08
Identities = 66/262 (25%), Positives = 98/262 (37%), Gaps = 24/262 (9%)
Query: 300 SPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSG 359
SP S +P TT+T +P + D SPP + P T KP +++ P S
Sbjct: 703 SPQSPPTPQTTLTPLQESPVISKDQSPPPSP-PPSYHPPPPPTKKP--EVVVEAPSASET 759
Query: 360 GAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIAT 419
P PPP A E L+ P E +PEP P+ + E+
Sbjct: 760 AEEPLQDPNWPPPPPPAPE------EQDLSMADFPPPEEAFFSVASPEPAGPSGSPEL-- 811
Query: 420 ASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDP 479
S+ A+++++ TA+ + D A P APA+S A P + G P
Sbjct: 812 VSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASS--APGHVAKLPQKEPVGCSKGGGP 869
Query: 480 FAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVP----------ATAPSPAPAV 529
G+ P L L ++ P PT + P P +P PAP+
Sbjct: 870 PREDVGAPLVTPSL-LQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSS 928
Query: 530 AAAAAATTAATAAATTTTTTSA 551
AA A + A + +SA
Sbjct: 929 GLHAAVRLKACSLAASEGLSSA 950
Score = 49.3 bits (116), Expect = 2e-05
Identities = 96/480 (20%), Positives = 152/480 (31%), Gaps = 78/480 (16%)
Query: 455 SEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTAST 514
S G AP P++ A+ +G G+ A P ++ P T + + P A
Sbjct: 309 STGTRAPPLTRPMSLAVPGLTG--------GAGPAEPLSPAMSISPQATYLSKLIPHAVL 360
Query: 515 APPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEV 574
P V A + + +A+ A+ + ++ ++ P + P
Sbjct: 361 PPTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRH---------PSS 411
Query: 575 AAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLL-----SVDAFAAPSPATTAS 629
++ + S + S + S G+ PESS ++ + +PS +TA
Sbjct: 412 SSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAE 471
Query: 630 PA---KVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSP---- 682
+ + SSG L G + + P + S L G + P P
Sbjct: 472 ASDTLSIRSSG--QLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQ 529
Query: 683 ------------------SPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPS--VFDGLG 722
+P P N P P S + PS G
Sbjct: 530 QPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSG 589
Query: 723 DLLMPTMAPAGQPA-PVSMVPPSPAMAAS-KALGSDLDSSLASLVGNLGISGTTTKKGDL 780
+P AG PA P PP P S ++ G+ + SSL SL + + + G
Sbjct: 590 TPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSG-- 647
Query: 781 QWNAGEKKLTGGANWQPKV-APATWSAGVPP--SAPLQGAVPPTSSVPPVAGAPSVGQPG 837
P++ P +PP P + PP+ P AP++ P
Sbjct: 648 ----------------PQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPA 691
Query: 838 AGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKKPPAKDP 897
G P P P P+ P + Q P P S P PP K P
Sbjct: 692 VVPGPVSTTDASPQSPPTPQTTLTPLQESP----VISKDQSPPPSPPPSYHPPPPPTKKP 747
Score = 43.1 bits (100), Expect = 0.001
Identities = 76/298 (25%), Positives = 113/298 (37%), Gaps = 49/298 (16%)
Query: 627 TASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSS------SASADLLAGFGGSFMAP 680
+ASPA V S G SS S PQP S+ SSS S S+D + G + +
Sbjct: 384 SASPASVRSLGRF--------SSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSK 435
Query: 681 SPSPVTP----AQNNLLQPNFEAAFGTTPS-TSSSSSFDPSVFDGLGDLLMPTMAPAGQP 735
S P A N+++ P + +PS S++ + D G L +++
Sbjct: 436 GGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLK 495
Query: 736 APVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQW----NAGEKKLTG 791
P PP P S LA G LG+ +K Q G + G
Sbjct: 496 RP----PPPPRRTHSLH-----QRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAG 546
Query: 792 GA--------NWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMP 843
A +W P ++P + PP +P + + P+S +G P++ P G P
Sbjct: 547 AAPCPPNPANSWVPGLSPG--GSRRPPRSP-ERTLSPSSGYSSQSGTPTL--PPKGLAGP 601
Query: 844 PAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQL-SPSPTPASQSPKKPPAKDPLAD 900
PA G P+ + + +R P + + T L S S PA P PL D
Sbjct: 602 PASPGKAQPPKPERVTS---LRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGD 656
>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 673
Score = 73.6 bits (179), Expect = 8e-13
Identities = 141/607 (23%), Positives = 213/607 (35%), Gaps = 102/607 (16%)
Query: 314 PNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPA 373
P TP++ T P T + + T PS+ L G + A+ PP A
Sbjct: 4 PTRTPSRASPTRTPSTASLTGTPSRASLTGTPSTASL-------MGTPSRASLTGTPPRA 56
Query: 374 G--GATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVT 431
G T+ L+ S A+L+ + S + + T + A + AS T T+
Sbjct: 57 SLKGTTSMASLMVSPSRASLTRMQSSSLL--------TRTPSMASLKRMPPRASRTRTLP 108
Query: 432 AVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTP-VAAALDACSGNDPFAPSEGSAEAA 490
+ + SP A + + A + TP AAAL PS S
Sbjct: 109 RASLMRRPSTASLTRSPSRASLTTTPSRASLSMTPSTAAALTM--------PSRASLTRT 160
Query: 491 PELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTS 550
P M P S+ P AS T+P+ P + A+ T + A+ T T S
Sbjct: 161 PPRASLTMTPSTASLTRTPPRASPTGMPSRTSPTGMP----STASLTKMDSTASITRTLS 216
Query: 551 AATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLT 610
A+ T PP G S P + + P A I +PP+ ASP S T
Sbjct: 217 RASPTGTPPRASPTG----SPPRASLSMMPSTALLI--------RTPPR-ASPTGMLSRT 263
Query: 611 ADLLSVDAFAA----PSPATTASPAKVDSSGVIDLFGDAFGSSASEPQ--PASQAASSSS 664
+ L +D+ A+ PS +TASP S + + P+ P + +S
Sbjct: 264 S-LTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSL 322
Query: 665 ASADLLAGFG----GSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDG 720
D A + + +PS +P +P+ + GT S + S + G
Sbjct: 323 TKMDSTASISRTPPRASITRTPSRASPTG----KPSTASPTGTPSRASPTGSPSTASLTG 378
Query: 721 LGDLLMPT-----MAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTT 775
L PT +P G P+ S+ P AS G L S T+
Sbjct: 379 LSSTASPTGTPPRASPTGTPSTASLTRKPPR---------------ASPTGML--SRTSI 421
Query: 776 KKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSA-----PLQGAVPPTSSVPPVAGA 830
K D P+ +P G PP A P + + T S G+
Sbjct: 422 TKMD--------STASPTRTPPRASP----TGTPPRASPTGTPSRASPTGTQSTASPTGS 469
Query: 831 PSVGQPGAGFGMPPAGTGMP---MMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQ 887
PS P G + TG P + + P + M P ++ SP+ TP++
Sbjct: 470 PSTASP-TGSPSTASPTGSPSRASLTRTPSRASLTKMESTASITRTP-SRASPTWTPSTA 527
Query: 888 SPKKPPA 894
SP P+
Sbjct: 528 SPTGSPS 534
Score = 72.8 bits (177), Expect = 1e-12
Identities = 144/600 (24%), Positives = 223/600 (37%), Gaps = 107/600 (17%)
Query: 302 LSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGA 361
++ S+ + T T P ++P + P + +TAS ST+ + L
Sbjct: 168 MTPSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTL------------ 215
Query: 362 AAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQ-ISDPFAPEPTPPTTTAEIATA 420
+ A+P PP T G A+LS +PS A I P PT + +
Sbjct: 216 -SRASPTGTPPRASPT------GSPPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKM 268
Query: 421 SASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPF 480
++AS T T + + ASP P+ + + P+T + + L S
Sbjct: 269 DSTASITRTPSRPST----------ASPTGTPSRASLSMTPSTAS-LMRMLPRASPTGML 317
Query: 481 APSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPV--PATAPSPAPAVAAAAAATTA 538
S S + PP S+ T T S A P P+TA +P + A+ T
Sbjct: 318 --SRTSLTKMDSTASISRTPPRASI---TRTPSRASPTGKPSTA---SPTGTPSRASPTG 369
Query: 539 ATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAP-KPDAAPSIDLFSTDAFSSP 597
+ + A+ T +S A+ T PP G TP A+ KP A + S + +
Sbjct: 370 SPSTASLTGLSSTASPTGTPPRASPTG-----TPSTASLTRKPPRASPTGMLSRTSITKM 424
Query: 598 PQGASPV---PESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQ 654
ASP P +S T P + T +P++ +G + S P
Sbjct: 425 DSTASPTRTPPRASPTG--------TPPRASPTGTPSRASPTGT-----QSTASPTGSPS 471
Query: 655 PASQAASSSSASADLLAGFGGSFMAPSPSPVT--PAQNNLLQPNFEAAFGTTPSTSSSSS 712
AS S S+AS GS PS + +T P++ +L + A+ TPS +S +
Sbjct: 472 TASPTGSPSTASPT------GS---PSRASLTRTPSRASLTKMESTASITRTPSRASPT- 521
Query: 713 FDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISG 772
+ PS T +P G P+ ++ SP+ AA S + +L
Sbjct: 522 WTPS-----------TASPTGSPS-TALAMGSPSRAALTRTPSRASLTRTPSRASL---- 565
Query: 773 TTTKKGDLQWNAGEKKLTG-GANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVP--PVAG 829
TT + L LT + P P+ S PS+ L + T+S+ P
Sbjct: 566 TTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITRTPPRA 625
Query: 830 APSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSP 889
+P+ P A P GT P A P PP + SP+ TP+ SP
Sbjct: 626 SPTETPPRAS----PTGTPPRASPTGTPPRASPTGTPP---------RASPTGTPSRASP 672
Score = 70.1 bits (170), Expect = 9e-12
Identities = 150/666 (22%), Positives = 233/666 (34%), Gaps = 78/666 (11%)
Query: 288 KKPGNNEGSGAPSPLSKS-SPATTVTSPNSTPAKTIDTSPPVDLFATAS-AAVPVSTSKP 345
+ P +G PS S + +P+T + A T P L T S A++ VS S+
Sbjct: 15 RTPSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRASLKGTTSMASLMVSPSRA 74
Query: 346 SSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATA-WGDLLGEDSLAALSSVPSEAQISD-P 403
S + + + A+ PP + T L+ S A+L+ PS A ++ P
Sbjct: 75 SLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTASLTRSPSRASLTTTP 134
Query: 404 FAPEPTPPTTTAEIATASASASTTTT-----VTAVTAEVDLFGDAFAASPGEAPAASEGA 458
+ +TA T + AS T T +T + L ASP P+ +
Sbjct: 135 SRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPSTASLTRTPPRASPTGMPSRTSPT 194
Query: 459 AAPATPT--------PVAAALDACS--GNDPFAPSEGSAEAA-----PELDLFAMKPPE- 502
P+T + + L S G P A GS A P L PP
Sbjct: 195 GMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPRASLSMMPSTALLIRTPPRA 254
Query: 503 --------TSVPVVTPTASTA--PPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAA 552
TS+ + TAS P P+TA SP + A+ + T +TA+ ++
Sbjct: 255 SPTGMLSRTSLTKMDSTASITRTPSRPSTA-SPTGTPSRASLSMTPSTASLMRMLPRASP 313
Query: 553 T---ATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSL 609
T + T+ +D + + P + P A ST + + P ASP S
Sbjct: 314 TGMLSRTSLTKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPSRASPTGSPS- 372
Query: 610 TADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADL 669
TA L + + A+P T +P + +G + S +P AS S S
Sbjct: 373 TASLTGLSSTASP----TGTPPRASPTGT-----PSTASLTRKPPRASPTGMLSRTSITK 423
Query: 670 LAGFGGSFMAP---SPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLM 726
+ P SP+ P + P+ + GT + S + S PS G
Sbjct: 424 MDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPTGS--PSTASPTGS--P 479
Query: 727 PTMAPAGQPAPVSMVPPSPAMAASKALGSDLD-------------SSLASLVGN--LGIS 771
T +P G P+ S+ +P+ A+ + S S AS G+ ++
Sbjct: 480 STASPTGSPSRASLTR-TPSRASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALA 538
Query: 772 GTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAP 831
+ + L LT + P+ S PS L +PP++S G P
Sbjct: 539 MGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRTPSTVLLTRMPPSASP---TGMP 595
Query: 832 SVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPASQSPKK 891
S P GMP + M + P P T P +P P+
Sbjct: 596 SRTSPT---GMPSSALLTKMDSTASITRTPPRASPTETPPRASPTGTPPRASPTGTPPRA 652
Query: 892 PPAKDP 897
P P
Sbjct: 653 SPTGTP 658
Score = 65.9 bits (159), Expect = 2e-10
Identities = 85/352 (24%), Positives = 133/352 (37%), Gaps = 48/352 (13%)
Query: 300 SPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSG 359
SP K S A SP TP++ T P +TAS ST+ P+ P S
Sbjct: 348 SPTGKPSTA----SPTGTPSRASPTGSP----STASLTGLSSTASPTGT----PPRASPT 395
Query: 360 GAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIAT 419
G + A+ PP T +L S+ + S S + +P TPP + T
Sbjct: 396 GTPSTASLTRKPPRASPTG---MLSRTSITKMDSTASPTRTPPRASPTGTPPRASPT-GT 451
Query: 420 ASASASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDP 479
S ++ T T TA SP +P+ + +P+T +P + A P
Sbjct: 452 PSRASPTGTQSTA--------------SPTGSPSTASPTGSPSTASPTGSPSRASLTRTP 497
Query: 480 FAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATA-----PSPAPAVAAAAA 534
S E+ + + P + P TP+ ++ P+TA PS A +
Sbjct: 498 SRASLTKMESTASI----TRTPSRASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSR 553
Query: 535 ATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPE-VAAAPKPDAAPSIDLF---- 589
A+ T + + TT S A+ T P + + ++P + + P PS L
Sbjct: 554 ASLTRTPSRASLTTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMD 613
Query: 590 STDAFSSPPQGASPV---PESSLTADLLSVDAFAAPSPAT-TASPAKVDSSG 637
ST + + P ASP P +S T P A+ T +P + +G
Sbjct: 614 STASITRTPPRASPTETPPRASPTGTPPRASPTGTPPRASPTGTPPRASPTG 665
Score = 57.4 bits (137), Expect = 6e-08
Identities = 78/344 (22%), Positives = 120/344 (34%), Gaps = 49/344 (14%)
Query: 267 LTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLS----KSSPATTVTSPNSTPAKTI 322
+T+ PS T + + G P +G+PS S S+ + T T P ++P T
Sbjct: 340 ITRTPSRASPTGKPSTASPTGT-PSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTP 398
Query: 323 DTSP---------PVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPA 373
T+ P + + S ST+ P+ P + A+ P+ P
Sbjct: 399 STASLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPT 458
Query: 374 G--------GATAWGDLLGEDSLAALSSVPSEAQIS-DPFAPEPTPPTTTAEIATASASA 424
G G+ + G S A+ + PS A ++ P T +TA I + A
Sbjct: 459 GTQSTASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRA 518
Query: 425 STTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFA-PS 483
S T T + + SP A A + A T TP A+L PS
Sbjct: 519 SPTWTPSTASP---------TGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPS 569
Query: 484 EGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATA---------------PSPAPA 528
S P L PP S P P+ ++ +P++A P +P
Sbjct: 570 RASLTRTPSTVLLTRMPPSAS-PTGMPSRTSPTGMPSSALLTKMDSTASITRTPPRASPT 628
Query: 529 VAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTP 572
A+ T A+ T T A+ T PP G ++P
Sbjct: 629 ETPPRASPTGTPPRASPTGTPPRASPTGTPPRASPTGTPSRASP 672
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 72.8 bits (177), Expect = 1e-12
Identities = 166/693 (23%), Positives = 226/693 (32%), Gaps = 118/693 (17%)
Query: 275 METLEQHLNTLEGKKPG--NNEGSGAPS--PLSKSSPATTVTS-PNSTPAKTIDTSPPVD 329
MET H + EG P + G PS P + P T + P S P + S
Sbjct: 117 METTCSHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFP 176
Query: 330 LFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATA----WG----- 380
A P + P P F G A + AP PPPPA A WG
Sbjct: 177 TLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAP-PPPPAISLNAPSYNWGAALRS 235
Query: 381 -----DLLGEDSLAALSSVPSEAQI---SDPFAPEPTPPTTTAEIATASASASTTTTVTA 432
DL + A SS PS+ + SD P P PP+ AS ++ T
Sbjct: 236 SLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATM 295
Query: 433 VTAEV--DLFGDAFAASPGEAP-------AASEGAAAPATPTPVA-------AALDACSG 476
V L G PG P +A+ A P P P A + S
Sbjct: 296 HLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASH 355
Query: 477 NDPFAPSEGSAEAAPEL-DLFAMKPPETSVPVVTPTASTAPPVPATAPSPA----PAVAA 531
+ PS+ P + L + P+T P A P P + P P+ P+V +
Sbjct: 356 SSSLRPSQRRPRRPPTVFRLLEGRGPQTP-RRSRPRAPAPVPQPFSLPEPSQPILPSVLS 414
Query: 532 AAAATTAATAAATTTTTTSAATATTAPPAL---------------DIFGDLFESTPEVAA 576
T + + + + A PP + G S V
Sbjct: 415 LLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPG 474
Query: 577 APKPDAAPSIDLFSTDAFSSPPQG-------ASPVPESSLTADLLSVDAFAAPSPATTAS 629
AP P AA + + SP +G A P+P L +AF PSP +
Sbjct: 475 APAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLP------PLAGGEAFPFPSPEQGLA 528
Query: 630 PAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQ 689
+ G++ S +P P+ S +L G GG P P P+ P
Sbjct: 529 LSGAGFPGMLGAL--PLPLSLGQPPPSPLLNHSLFG---VLTGGGGQ---PPPEPLLPPP 580
Query: 690 NNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAA 749
G P + PS+ + LL P P P PPS +A+
Sbjct: 581 G-----------GPGPPLAPGEPEGPSLL--VASLLPP---PPSDLLPPPSAPPSNLLAS 624
Query: 750 ---SKALGSDLDSSLASLVGNLGISGTT-TKKGDLQWNAGEKKLTGGANWQPKVAPATWS 805
ALG S G G SG + GDL + P AP T
Sbjct: 625 FLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDL----------SPLLFPPLSAPPTLI 674
Query: 806 AGVPPSAPLQGAVPPTSSVPP---VAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQP 862
A SA L + P S PP V AP G P + G + + P +P
Sbjct: 675 A--LNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRP 732
Query: 863 --MMRPPFGAAAVPGTQLSPSPTPASQSPKKPP 893
++ P GA+ + S A S +PP
Sbjct: 733 PQLLSPLLGASLLGDLSSLTSSPGALPSLLQPP 765
Score = 45.8 bits (107), Expect = 2e-04
Identities = 130/588 (22%), Positives = 194/588 (32%), Gaps = 100/588 (17%)
Query: 297 GAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDF 356
GAP+ +P +S S AK PP+ +T P + + +S L+P
Sbjct: 306 GAPTVEGPGAPPFLASSLLSAAAKA--QHPPLPPPSTLQGRRPRAQAPSASHSSSLRP-- 361
Query: 357 SSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVP-SEAQISDPFA-PEPTPPTTT 414
+ P PP T + L G S P + A + PF+ PEP+ P
Sbjct: 362 ------SQRRPRRPP-----TVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILP 410
Query: 415 AEIATASASASTTTTVTAVTAEVDLFG-DAFAASPGEAPAASEGAAAPATPTPVAAALDA 473
+ + S T + +L G DA P P S G+ P P+ +L
Sbjct: 411 SVL---SLLGLPTPGPSHSDGSFNLLGSDAHLPPP---PTLSSGSP-PQPRHPIQPSLPG 463
Query: 474 CSGND----PFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAV 529
+ P AP+ +A AP + ++ P + + A PP+ P P+
Sbjct: 464 TTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSP 523
Query: 530 AAAAAATTAATAAATTTTTTSAATATTAPPAL---DIFGDLF----ESTPEVAAAPKPDA 582
A + A + P L +FG L + PE P
Sbjct: 524 EQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGP 583
Query: 583 APSI--------DLFSTDAFSSPPQGASP---VPESSLTADLLSVDAFAAP------SPA 625
P + L PP P P S+L A L + A S
Sbjct: 584 GPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAE 643
Query: 626 TTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGS---FMAPSP 682
P+ SG+ DL F ++ P + ++ +A+ D +G AP P
Sbjct: 644 GAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQP 703
Query: 683 SPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDG---LGDLLMPTMAPAGQPAPVS 739
P T + ++ G PS S S G LGDL T +P P+ +
Sbjct: 704 GPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQ 763
Query: 740 MVPPSPAMAASKALG-----------SDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKK 788
PP P ++ L S+ S LA L+ +L I
Sbjct: 764 --PPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPE--------------- 806
Query: 789 LTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQP 836
QP+ AP +PP +P P + P A AP G P
Sbjct: 807 -------QPE-APC-----LPPESPASALEPEPARPPLSALAPPHGSP 841
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.125 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,618,730
Number of Sequences: 37866
Number of extensions: 2485064
Number of successful extensions: 42383
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 445
Number of HSP's successfully gapped in prelim test: 1580
Number of HSP's that attempted gapping in prelim test: 16884
Number of HSP's gapped (non-prelim): 12879
length of query: 907
length of database: 18,247,518
effective HSP length: 111
effective length of query: 796
effective length of database: 14,044,392
effective search space: 11179336032
effective search space used: 11179336032
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.