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Search of human proteins with 7657303
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]
(402 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens] 832 0.0
gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens] 776 0.0
gi|15375314 LIM homeobox protein 4 [Homo sapiens] 507 e-144
gi|11641283 LIM homeobox protein 5 [Homo sapiens] 245 6e-65
gi|30410785 LIM homeobox protein 1 [Homo sapiens] 235 6e-62
gi|28893581 LIM homeobox transcription factor 1, alpha isoform a... 188 8e-48
gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens] 177 1e-44
gi|21956641 ISL LIM homeobox 2 [Homo sapiens] 164 1e-40
gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens] 163 3e-40
gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens] 163 3e-40
gi|115387114 islet-1 [Homo sapiens] 162 7e-40
gi|50083287 LIM homeobox 8 [Homo sapiens] 157 1e-38
gi|30795196 LIM homeobox protein 2 [Homo sapiens] 132 6e-31
gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens] 130 2e-30
gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens] 130 2e-30
gi|21361802 LIM domain only 3 [Homo sapiens] 119 4e-27
gi|47778935 LIM domain only 3 [Homo sapiens] 119 4e-27
gi|4505005 LIM domain only 1 [Homo sapiens] 118 8e-27
gi|5803072 LIM domain only 4 [Homo sapiens] 114 1e-25
gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens] 97 3e-20
gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens] 97 3e-20
gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens] 97 3e-20
gi|4505001 LIM domain kinase 1 [Homo sapiens] 94 2e-19
gi|194272196 actin binding LIM protein family, member 2 isoform ... 89 5e-18
gi|194272200 actin binding LIM protein family, member 2 isoform ... 87 2e-17
gi|194272198 actin binding LIM protein family, member 2 isoform ... 87 2e-17
gi|153792514 actin binding LIM protein family, member 2 isoform ... 87 3e-17
gi|194272202 actin binding LIM protein family, member 2 isoform ... 87 3e-17
gi|194272207 actin binding LIM protein family, member 2 isoform ... 86 5e-17
gi|194272204 actin binding LIM protein family, member 2 isoform ... 86 5e-17
>gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]
Length = 402
Score = 832 bits (2148), Expect = 0.0
Identities = 402/402 (100%), Positives = 402/402 (100%)
Query: 1 MEARGELGPARESAGGDLLLALLARRADLRREIPLCAGCDQHILDRFILKALDRHWHSKC 60
MEARGELGPARESAGGDLLLALLARRADLRREIPLCAGCDQHILDRFILKALDRHWHSKC
Sbjct: 1 MEARGELGPARESAGGDLLLALLARRADLRREIPLCAGCDQHILDRFILKALDRHWHSKC 60
Query: 61 LKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHC 120
LKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHC
Sbjct: 61 LKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHC 120
Query: 121 FACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSA 180
FACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSA
Sbjct: 121 FACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSA 180
Query: 181 YNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSR 240
YNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSR
Sbjct: 181 YNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSR 240
Query: 241 GGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSL 300
GGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSL
Sbjct: 241 GGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSL 300
Query: 301 EHGGLAGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGP 360
EHGGLAGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGP
Sbjct: 301 EHGGLAGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGP 360
Query: 361 PPMRVLAGNGPSSDLSTGSSGGYPDFPASPASWLDEVDHAQF 402
PPMRVLAGNGPSSDLSTGSSGGYPDFPASPASWLDEVDHAQF
Sbjct: 361 PPMRVLAGNGPSSDLSTGSSGGYPDFPASPASWLDEVDHAQF 402
>gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]
Length = 397
Score = 776 bits (2004), Expect = 0.0
Identities = 372/372 (100%), Positives = 372/372 (100%)
Query: 31 REIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKR 90
REIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKR
Sbjct: 26 REIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKR 85
Query: 91 FGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY 150
FGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY
Sbjct: 86 FGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY 145
Query: 151 ETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWF 210
ETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWF
Sbjct: 146 ETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWF 205
Query: 211 QNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAE 270
QNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAE
Sbjct: 206 QNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAE 265
Query: 271 MGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQ 330
MGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQ
Sbjct: 266 MGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQ 325
Query: 331 SLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPDFPASP 390
SLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPDFPASP
Sbjct: 326 SLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPDFPASP 385
Query: 391 ASWLDEVDHAQF 402
ASWLDEVDHAQF
Sbjct: 386 ASWLDEVDHAQF 397
>gi|15375314 LIM homeobox protein 4 [Homo sapiens]
Length = 390
Score = 507 bits (1306), Expect = e-144
Identities = 250/377 (66%), Positives = 299/377 (79%), Gaps = 16/377 (4%)
Query: 31 REIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKR 90
++IP CAGC+QHILD+FILK LDRHWHS CLKC+DC LA+RCFSR SVYCK+DFFKR
Sbjct: 25 QQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKR 84
Query: 91 FGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY 150
FGTKC ACQ GIPPTQVVR+AQDFVYHLHCFAC++C RQLATGDEFYLMED RLVCK DY
Sbjct: 85 FGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDY 144
Query: 151 ETAKQR-EAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVW 209
ETAKQ ++EA AKRPRTTITAKQLETLK+AY SPKPARHVREQLSSETGLDMRVVQVW
Sbjct: 145 ETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVW 204
Query: 210 FQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQD-SDAEVSFPDEPSL 268
FQNRRAKEKRLKKDAGR RWGQ+++++KRSRG SK +K+S E SD+E+SF ++ L
Sbjct: 205 FQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFREDQIL 264
Query: 269 AEMGPANGLYGSLGEPTQALGRPSGAL--GNFSLEHGGLAGPEQYRELRPGSPYGVPPSP 326
+E+G N +YG++G+ T G L G+FS++ G + Y++LR GSPYG+P SP
Sbjct: 265 SELGHTNRIYGNVGDVT------GGQLMNGSFSMDGTG----QSYQDLRDGSPYGIPQSP 314
Query: 327 AAPQSLPGPQPLLSSLVYP-DTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPD 385
++ SLP PLL+ L Y D++LG++ G +R +AG GP+SD+STGSS GYPD
Sbjct: 315 SSISSLPSHAPLLNGLDYTVDSNLGIIAHAGQGVSQTLRAMAG-GPTSDISTGSSVGYPD 373
Query: 386 FPASPASWLDEVDHAQF 402
FP SP SWLDE+DH F
Sbjct: 374 FPTSPGSWLDEMDHPPF 390
>gi|11641283 LIM homeobox protein 5 [Homo sapiens]
Length = 402
Score = 245 bits (625), Expect = 6e-65
Identities = 157/418 (37%), Positives = 218/418 (52%), Gaps = 81/418 (19%)
Query: 36 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKC 95
CAGC++ ILDRF+L LDR WH KC++C +C T L+E+CFSR +YCK+DFF+RFGTKC
Sbjct: 5 CAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFSREGKLYCKNDFFRRFGTKC 64
Query: 96 AACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY----- 150
A C GI P+ +VR+A+ V+HL+CF C+VC +QL+TG+E Y++++++ VCK DY
Sbjct: 65 AGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYLSSSS 124
Query: 151 ----------------------------------------ETAKQREAEATA----KRPR 166
ETA E + + PR
Sbjct: 125 LKEGSLNSVSSCTDRSLSPDLQDALQDDPKETDNSTSSDKETANNENEEQNSGTKRRGPR 184
Query: 167 TTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK-DAG 225
TTI AKQLETLK+A+ +PKP RH+REQL+ ETGL+MRV+QVWFQNRR+KE+R+K+ A
Sbjct: 185 TTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSAL 244
Query: 226 RQRWGQYFRNMKRSRG-GSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEP 284
R +FR+ +R R G + D+ E S + D +N + + G P
Sbjct: 245 GARRHAFFRSPRRMRPLGGRLDE---SEMLGSTPYTYYGDYQGDYYAPGSNYDFFAHGPP 301
Query: 285 TQALGRPSGALGNFSLEHGGLAGPEQYRELRPGS-PYG-VPPSPAAPQSLPGPQPLLSSL 342
+QA S A +F G PGS P G + P A P + P+ +
Sbjct: 302 SQA---QSPADSSFLAASG------------PGSTPLGALEPPLAGPHAADNPR-FTDMI 345
Query: 343 VYPDTSLGLVPSGAPGGPPPMRVLAG----NGPSSDLSTGSSGGYPDFPASPASWLDE 396
+PDT PS PG P + + G GPS + GY + P L+E
Sbjct: 346 SHPDT-----PSPEPGLPGTLHPMPGEVFSGGPSPPFPMSGTSGYSGPLSHPNPELNE 398
>gi|30410785 LIM homeobox protein 1 [Homo sapiens]
Length = 406
Score = 235 bits (599), Expect = 6e-62
Identities = 153/416 (36%), Positives = 206/416 (49%), Gaps = 108/416 (25%)
Query: 36 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKC 95
CAGC + ILDRF+L LDR WH KC++C +C L E+CFSR +YCK+DFF+ FGTKC
Sbjct: 4 CAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRCFGTKC 63
Query: 96 AACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY----- 150
A C GI P+ +VRRA+ V+HL+CF C++C +QL+TG+E Y++++++ VCK DY
Sbjct: 64 AGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLSNSS 123
Query: 151 ---------------------------------ETAKQREAEA----------TAKR--P 165
E+A + EA AKR P
Sbjct: 124 VAKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEAGSNENDDQNLGAKRRGP 183
Query: 166 RTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK-DA 224
RTTI AKQLETLK+A+ +PKP RH+REQL+ ETGL+MRV+QVWFQNRR+KE+R+K+ A
Sbjct: 184 RTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSA 243
Query: 225 GRQRWGQYFRNMKRSRG---------------------------GSKSDKDSVQEGQDSD 257
R +FR+ +R R G + D +G S
Sbjct: 244 LGARRHAFFRSPRRMRPLVDRLEPGELIPNGPFSFYGDYQSEYYGPGGNYDFFPQGPPSS 303
Query: 258 AEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPG 317
+ D P + GP+ G L P PS F+ LA P PG
Sbjct: 304 QAQTPVDLPFVPSSGPSGTPLGGLEHPLPG-HHPSSEAQRFT---DILAHP-------PG 352
Query: 318 SPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSS 373
SP+ SLPGP +S+ V+ G PP L+ NG +S
Sbjct: 353 D------SPSPEPSLPGPLHSMSAEVF-------------GPSPPFSSLSVNGGAS 389
>gi|28893581 LIM homeobox transcription factor 1, alpha isoform a
[Homo sapiens]
Length = 382
Score = 188 bits (477), Expect = 8e-48
Identities = 97/232 (41%), Positives = 128/232 (55%), Gaps = 36/232 (15%)
Query: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTK 94
+C GC + ILDRF+L+ D WH +C++C+ C PL CF R + +YCK D+ K F K
Sbjct: 34 VCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCKYDYEKLFAVK 93
Query: 95 CAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE--- 151
C C I P + V RAQ VYHL CF C VC+RQL GDEF L E +L+CK DYE
Sbjct: 94 CGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKE-GQLLCKGDYEKER 152
Query: 152 --------------------------------TAKQREAEATAKRPRTTITAKQLETLKS 179
TA++ + KRPRT +T +Q K+
Sbjct: 153 ELLSLVSPAASDSGKSDDEESLCKSAHGAGKGTAEEGKDHKRPKRPRTILTTQQRRAFKA 212
Query: 180 AYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQ 231
++ S KP R VRE L++ETGL +RVVQVWFQN+RAK K+L + +Q+ Q
Sbjct: 213 SFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQ 264
>gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens]
Length = 372
Score = 177 bits (450), Expect = 1e-44
Identities = 109/306 (35%), Positives = 149/306 (48%), Gaps = 48/306 (15%)
Query: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTK 94
+C GC + I DRF+++ + WH +CL+C+ C L C+ R +YCK D+ + F K
Sbjct: 32 VCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAK 91
Query: 95 CAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAK 154
C+ C I PT+ V RA + VYHL CF C VC+RQL GDEF L E +L+CK DYE K
Sbjct: 92 CSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKE-GQLLCKGDYEKEK 150
Query: 155 QREAEAT--------------------------------------AKRPRTTITAKQLET 176
+ + KRPRT +T +Q
Sbjct: 151 DLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRA 210
Query: 177 LKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNM 236
K+++ S KP R VRE L++ETGL +RVVQVWFQN+RAK K+L A R + Q +N
Sbjct: 211 FKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKL---ARRHQQQQEQQNS 267
Query: 237 KRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPSGALG 296
+R + S EG + P + + M YGS +P Q P G
Sbjct: 268 QRL---GQEVLSSRMEGMMASYTPLAPPQQQIVAM--EQSPYGS-SDPFQQGLTPPQMPG 321
Query: 297 NFSLEH 302
N S+ H
Sbjct: 322 NDSIFH 327
>gi|21956641 ISL LIM homeobox 2 [Homo sapiens]
Length = 359
Score = 164 bits (415), Expect = 1e-40
Identities = 115/342 (33%), Positives = 161/342 (47%), Gaps = 61/342 (17%)
Query: 35 LCAGCDQHILDRFILKAL-DRHWHSKCLKCSDCHTPLAERC--FSRGESVYCKDDFFKRF 91
+C GC I D+FIL+ D WH+ CLKC++C L E C F R YCK D+ + F
Sbjct: 26 MCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLF 85
Query: 92 GTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 151
G KCA CQ+G + +V RA+D VYH+ CF C VC RQL GDEF L E L+C+AD+
Sbjct: 86 GIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLRE-HELLCRADHG 144
Query: 152 TAKQREAEATAKRP------------------------------------RTTITAKQLE 175
+R A + + P RT + KQL
Sbjct: 145 LLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPALRPHVHKQTEKTTRVRTVLNEKQLH 204
Query: 176 TLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRN 235
TL++ Y +P+P ++EQL TGL RV++VWFQN+R K+K+ K +Q Q +
Sbjct: 205 TLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK-KSILMKQLQQQQHSD 263
Query: 236 MKRSRG--------GSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPT-Q 286
+G GS ++ +G + + P +L+E L L +P Q
Sbjct: 264 KTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPPWKALSEF----ALQSDLDQPAFQ 319
Query: 287 AL--GRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSP 326
L SG+LGN S G +L P +P + PSP
Sbjct: 320 QLVSFSESGSLGNSS----GSDVTSLSSQL-PDTPNSMVPSP 356
>gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens]
Length = 377
Score = 163 bits (412), Expect = 3e-40
Identities = 82/209 (39%), Positives = 123/209 (58%), Gaps = 25/209 (11%)
Query: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFSRGESVYCKDDFFKRFG 92
+C+ C ILDR++LK + WH +CL+CS C T L ++ C+ + + ++CK D+F RFG
Sbjct: 98 ICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFG 157
Query: 93 TKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYET 152
TKCA C I + VRRA+ YHL CFAC CKRQL+TG+EF L+E+ +++C+ Y+T
Sbjct: 158 TKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEE-KVLCRIHYDT 216
Query: 153 ----------------------AKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARH 190
++Q AKR RT+ TA+QL+ +++ + P
Sbjct: 217 MIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQ 276
Query: 191 VREQLSSETGLDMRVVQVWFQNRRAKEKR 219
++L+ TGL RV+QVWFQN RA+ K+
Sbjct: 277 TLQKLADMTGLSRRVIQVWFQNCRARHKK 305
>gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens]
Length = 392
Score = 163 bits (412), Expect = 3e-40
Identities = 82/209 (39%), Positives = 123/209 (58%), Gaps = 25/209 (11%)
Query: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFSRGESVYCKDDFFKRFG 92
+C+ C ILDR++LK + WH +CL+CS C T L ++ C+ + + ++CK D+F RFG
Sbjct: 98 ICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFG 157
Query: 93 TKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYET 152
TKCA C I + VRRA+ YHL CFAC CKRQL+TG+EF L+E+ +++C+ Y+T
Sbjct: 158 TKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEE-KVLCRIHYDT 216
Query: 153 ----------------------AKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARH 190
++Q AKR RT+ TA+QL+ +++ + P
Sbjct: 217 MIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQ 276
Query: 191 VREQLSSETGLDMRVVQVWFQNRRAKEKR 219
++L+ TGL RV+QVWFQN RA+ K+
Sbjct: 277 TLQKLADMTGLSRRVIQVWFQNCRARHKK 305
>gi|115387114 islet-1 [Homo sapiens]
Length = 349
Score = 162 bits (409), Expect = 7e-40
Identities = 87/229 (37%), Positives = 121/229 (52%), Gaps = 40/229 (17%)
Query: 30 RREIPLCAGCDQHILDRFILKAL-DRHWHSKCLKCSDCHTPLAERC--FSRGESVYCKDD 86
+R I LC GC I D++IL+ D WH+ CLKC++C+ L E C F R YCK D
Sbjct: 11 KRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRD 70
Query: 87 FFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVC 146
+ + +G KCA C +G V RA+ VYH+ CF CV C RQL GDEF L ED L C
Sbjct: 71 YIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDG-LFC 129
Query: 147 KADYETAKQREAEA--------------------TAKRP----------------RTTIT 170
+AD++ ++ A +A++P RT +
Sbjct: 130 RADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLN 189
Query: 171 AKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKR 219
KQL TL++ Y +P+P ++EQL TGL RV++VWFQN+R K+K+
Sbjct: 190 EKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 238
>gi|50083287 LIM homeobox 8 [Homo sapiens]
Length = 356
Score = 157 bits (398), Expect = 1e-38
Identities = 81/210 (38%), Positives = 120/210 (57%), Gaps = 26/210 (12%)
Query: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFSRGESVYCKDDFFKRFG 92
+C C I+D+++LK D WH +CL CS C T L C+ + + ++CK D+F+R+G
Sbjct: 74 VCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYG 133
Query: 93 TKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYET 152
T+C+ C I T VRRA+ VYHL CFAC CKRQL+TG+EF L+E+ +++C+ Y+
Sbjct: 134 TRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEE-KVLCRVHYDC 192
Query: 153 A---KQREAE--------------------ATAKRPRTTITAKQLETLKSAYNTSPKPAR 189
+RE E AKR RT+ TA QL+ +++ + P
Sbjct: 193 MLDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDA 252
Query: 190 HVREQLSSETGLDMRVVQVWFQNRRAKEKR 219
++L+ TGL RV+QVWFQN RA+ K+
Sbjct: 253 QTLQKLAERTGLSRRVIQVWFQNCRARHKK 282
>gi|30795196 LIM homeobox protein 2 [Homo sapiens]
Length = 406
Score = 132 bits (332), Expect = 6e-31
Identities = 64/149 (42%), Positives = 86/149 (57%), Gaps = 4/149 (2%)
Query: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFSRGESVYCKDDFFKRFG 92
LCAGC I DR+ L A+D+ WH +CLKC +C L CFS+ S+YCK+D+++RF
Sbjct: 52 LCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFS 111
Query: 93 T-KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 151
+CA C LGI +++V RA+D VYHL+CF C C + L TGD F M+DS + C+ +E
Sbjct: 112 VQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFG-MKDSLVYCRLHFE 170
Query: 152 TAKQREAEATAKRPRTTITAKQLETLKSA 180
Q E A A KSA
Sbjct: 171 ALLQGEYPAHFNHADVAAAAAAAAAAKSA 199
Score = 52.4 bits (124), Expect = 7e-07
Identities = 27/57 (47%), Positives = 36/57 (63%)
Query: 163 KRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKR 219
KR RT+ QL T+KS + + P +QL+ +TGL RV+QVWFQN RAK +R
Sbjct: 267 KRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRR 323
>gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens]
Length = 397
Score = 130 bits (327), Expect = 2e-30
Identities = 60/126 (47%), Positives = 82/126 (65%), Gaps = 4/126 (3%)
Query: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFSRGESVYCKDDFFKRFG 92
LCAGC I DR+ L A+D+ WH +CLKC +C L CF++ S+YCK+D+++RF
Sbjct: 70 LCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFS 129
Query: 93 T-KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 151
+CA C LGI +++V RA+D VYHL CF C C + L TGD F M+DS + C+A +E
Sbjct: 130 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFG-MKDSLVYCRAHFE 188
Query: 152 TAKQRE 157
T Q E
Sbjct: 189 TLLQGE 194
Score = 55.8 bits (133), Expect = 7e-08
Identities = 55/205 (26%), Positives = 83/205 (40%), Gaps = 22/205 (10%)
Query: 30 RREIPLCAGCDQHI-LDRFILKALDRHWHSKCLKCSDCHTPLA--ERCFSRGESVYCKDD 86
R + CA C I +++A D +H C CS C+ L + + VYC+
Sbjct: 127 RFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAH 186
Query: 87 FFKRFGTKCAACQLGIPP----TQVVRRAQDFVYHLHCFACVVCK------RQLATGDEF 136
F Q PP T++ ++ V K + A G +
Sbjct: 187 FE-------TLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDI 239
Query: 137 YLMEDSRLVCKADYETAKQREAEAT--AKRPRTTITAKQLETLKSAYNTSPKPARHVREQ 194
+AD+ Q+ + KR RT+ QL T+KS + + P +Q
Sbjct: 240 VNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQ 299
Query: 195 LSSETGLDMRVVQVWFQNRRAKEKR 219
L+ +TGL RV+QVWFQN RAK +R
Sbjct: 300 LAQKTGLTKRVLQVWFQNARAKFRR 324
>gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens]
Length = 388
Score = 130 bits (327), Expect = 2e-30
Identities = 60/126 (47%), Positives = 82/126 (65%), Gaps = 4/126 (3%)
Query: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFSRGESVYCKDDFFKRFG 92
LCAGC I DR+ L A+D+ WH +CLKC +C L CF++ S+YCK+D+++RF
Sbjct: 61 LCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFS 120
Query: 93 T-KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 151
+CA C LGI +++V RA+D VYHL CF C C + L TGD F M+DS + C+A +E
Sbjct: 121 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFG-MKDSLVYCRAHFE 179
Query: 152 TAKQRE 157
T Q E
Sbjct: 180 TLLQGE 185
Score = 55.8 bits (133), Expect = 7e-08
Identities = 55/205 (26%), Positives = 83/205 (40%), Gaps = 22/205 (10%)
Query: 30 RREIPLCAGCDQHI-LDRFILKALDRHWHSKCLKCSDCHTPLA--ERCFSRGESVYCKDD 86
R + CA C I +++A D +H C CS C+ L + + VYC+
Sbjct: 118 RFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAH 177
Query: 87 FFKRFGTKCAACQLGIPP----TQVVRRAQDFVYHLHCFACVVCK------RQLATGDEF 136
F Q PP T++ ++ V K + A G +
Sbjct: 178 FE-------TLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDI 230
Query: 137 YLMEDSRLVCKADYETAKQREAEAT--AKRPRTTITAKQLETLKSAYNTSPKPARHVREQ 194
+AD+ Q+ + KR RT+ QL T+KS + + P +Q
Sbjct: 231 VNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQ 290
Query: 195 LSSETGLDMRVVQVWFQNRRAKEKR 219
L+ +TGL RV+QVWFQN RAK +R
Sbjct: 291 LAQKTGLTKRVLQVWFQNARAKFRR 315
>gi|21361802 LIM domain only 3 [Homo sapiens]
Length = 145
Score = 119 bits (299), Expect = 4e-27
Identities = 55/134 (41%), Positives = 84/134 (62%), Gaps = 6/134 (4%)
Query: 36 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAE---RCFSRGESVYCKDDFFKRFG 92
CAGC++ I DR++LKALD++WH CLKC+ C L E +++ + C+ D+ + FG
Sbjct: 13 CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFG 72
Query: 93 T--KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY 150
CAAC IP ++V RA+D VYHL CFAC +C ++ GD+F+L +++ ++C+ DY
Sbjct: 73 VTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL-KNNMILCQTDY 131
Query: 151 ETAKQREAEATAKR 164
E +E A R
Sbjct: 132 EEGLMKEGYAPQVR 145
>gi|47778935 LIM domain only 3 [Homo sapiens]
Length = 145
Score = 119 bits (299), Expect = 4e-27
Identities = 55/134 (41%), Positives = 84/134 (62%), Gaps = 6/134 (4%)
Query: 36 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAE---RCFSRGESVYCKDDFFKRFG 92
CAGC++ I DR++LKALD++WH CLKC+ C L E +++ + C+ D+ + FG
Sbjct: 13 CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFG 72
Query: 93 T--KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY 150
CAAC IP ++V RA+D VYHL CFAC +C ++ GD+F+L +++ ++C+ DY
Sbjct: 73 VTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL-KNNMILCQTDY 131
Query: 151 ETAKQREAEATAKR 164
E +E A R
Sbjct: 132 EEGLMKEGYAPQVR 145
>gi|4505005 LIM domain only 1 [Homo sapiens]
Length = 156
Score = 118 bits (296), Expect = 8e-27
Identities = 53/121 (43%), Positives = 81/121 (66%), Gaps = 6/121 (4%)
Query: 36 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAE---RCFSRGESVYCKDDFFKRFG 92
CAGC++ I DR++LKALD++WH CLKC+ C L E +++ + C+ D+ + FG
Sbjct: 24 CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFG 83
Query: 93 T--KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY 150
T CAAC IP ++V RA+D VYHL CFAC +C ++ GD+F+L +++ ++C+ DY
Sbjct: 84 TTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFL-KNNMILCQMDY 142
Query: 151 E 151
E
Sbjct: 143 E 143
>gi|5803072 LIM domain only 4 [Homo sapiens]
Length = 165
Score = 114 bits (286), Expect = 1e-25
Identities = 53/123 (43%), Positives = 75/123 (60%), Gaps = 6/123 (4%)
Query: 36 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAE---RCFSRGESVYCKDDFFKRFG 92
CAGC I DRF+L A+D +WHS+CLKCS C L + C+++ + C++D+ + FG
Sbjct: 23 CAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDIGTSCYTKSGMILCRNDYIRLFG 82
Query: 93 TK--CAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY 150
C+AC IP +++V RAQ VYHL CF C C+ +L GD F+ + S L C+ D
Sbjct: 83 NSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRNRLVPGDRFHYINGS-LFCEHDR 141
Query: 151 ETA 153
TA
Sbjct: 142 PTA 144
>gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens]
Length = 158
Score = 96.7 bits (239), Expect = 3e-20
Identities = 49/125 (39%), Positives = 69/125 (55%), Gaps = 7/125 (5%)
Query: 36 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAE---RCFSRGESVYCKDDFFKRFG 92
C GC Q+I DR+ LKA+D++WH CL C C L E R + + C+ D+ + FG
Sbjct: 30 CGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFG 89
Query: 93 TK--CAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKAD- 149
CA+C I ++ R +D VYHL CF C C++ GD YL+ +S +VC+ D
Sbjct: 90 QDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDR-YLLINSDIVCEQDI 148
Query: 150 YETAK 154
YE K
Sbjct: 149 YEWTK 153
>gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens]
Length = 158
Score = 96.7 bits (239), Expect = 3e-20
Identities = 49/125 (39%), Positives = 69/125 (55%), Gaps = 7/125 (5%)
Query: 36 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAE---RCFSRGESVYCKDDFFKRFG 92
C GC Q+I DR+ LKA+D++WH CL C C L E R + + C+ D+ + FG
Sbjct: 30 CGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFG 89
Query: 93 TK--CAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKAD- 149
CA+C I ++ R +D VYHL CF C C++ GD YL+ +S +VC+ D
Sbjct: 90 QDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDR-YLLINSDIVCEQDI 148
Query: 150 YETAK 154
YE K
Sbjct: 149 YEWTK 153
>gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens]
Length = 227
Score = 96.7 bits (239), Expect = 3e-20
Identities = 49/125 (39%), Positives = 69/125 (55%), Gaps = 7/125 (5%)
Query: 36 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAE---RCFSRGESVYCKDDFFKRFG 92
C GC Q+I DR+ LKA+D++WH CL C C L E R + + C+ D+ + FG
Sbjct: 99 CGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFG 158
Query: 93 TK--CAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKAD- 149
CA+C I ++ R +D VYHL CF C C++ GD YL+ +S +VC+ D
Sbjct: 159 QDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDR-YLLINSDIVCEQDI 217
Query: 150 YETAK 154
YE K
Sbjct: 218 YEWTK 222
>gi|4505001 LIM domain kinase 1 [Homo sapiens]
Length = 647
Score = 94.4 bits (233), Expect = 2e-19
Identities = 41/115 (35%), Positives = 63/115 (54%), Gaps = 1/115 (0%)
Query: 32 EIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRF 91
E+P+CA C Q I D L+AL+ WH+ C +C DC L+ + + + ++CK D++ R+
Sbjct: 21 ELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQYYEKDGQLFCKKDYWARY 80
Query: 92 GTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVC 146
G C C I +V A + YH CF C+ C + GD + L+E S+L C
Sbjct: 81 GESCHGCSEQI-TKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYC 134
Score = 32.0 bits (71), Expect = 1.0
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 4/56 (7%)
Query: 95 CAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY 150
CA+C I Q ++ A + +H CF C C L+ Y +D +L CK DY
Sbjct: 25 CASCGQRIYDGQYLQ-ALNADWHADCFRCCDCSASLS---HQYYEKDGQLFCKKDY 76
>gi|194272196 actin binding LIM protein family, member 2 isoform 1
[Homo sapiens]
Length = 645
Score = 89.4 bits (220), Expect = 5e-18
Identities = 77/272 (28%), Positives = 108/272 (39%), Gaps = 25/272 (9%)
Query: 27 ADLRREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDD 86
A L + + C GC I + L ALD+HWH C KC C L S+ YC+ D
Sbjct: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEAD 203
Query: 87 FFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDS--RL 144
+ +FG +C +C+ I T V A + YH C CV C + A G+E YL S
Sbjct: 204 YHAKFGIRCDSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHP 261
Query: 145 VCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMR 204
C R+A T R + T T+ + A +TS P+R + +L E LD R
Sbjct: 262 AC---------RQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEI-LDYR 311
Query: 205 VVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPD 264
+ + + D R Y + S G D+ S EG D
Sbjct: 312 DLAA------LPKSKAIYDIDRPDMISYSPYISHSAG----DRQSYGEGDQDDRSYKQCR 361
Query: 265 EPSLAEMGPAN-GLYGSLGEPTQALGRPSGAL 295
S + G + G Y Q RP+G +
Sbjct: 362 TSSPSSTGSVSLGRYTPTSRSPQHYSRPAGTV 393
Score = 55.8 bits (133), Expect = 7e-08
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVY-CKDDFFKRFGT 93
LC C ++ +L+ D+++H KC C C LAE F + Y C D+ + +GT
Sbjct: 23 LCNTCG-NVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGT 81
Query: 94 KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGD 134
+C +C I V A YH CF C VC+ GD
Sbjct: 82 RCFSCDQFIEGEVV--SALGKTYHPDCFVCAVCRLPFPPGD 120
Score = 35.0 bits (79), Expect = 0.12
Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 108 VRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 151
V R QD +H+ CF C C LA G + + +C DY+
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGG--FFVRQGEYICTLDYQ 76
>gi|194272200 actin binding LIM protein family, member 2 isoform 3
[Homo sapiens]
Length = 572
Score = 87.4 bits (215), Expect = 2e-17
Identities = 77/273 (28%), Positives = 106/273 (38%), Gaps = 25/273 (9%)
Query: 27 ADLRREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDD 86
A L + + C GC I + L ALD+HWH C KC C L S+ YC+ D
Sbjct: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEAD 203
Query: 87 FFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDS--RL 144
+ +FG +C +C+ I T V A + YH C CV C + A G+E YL S
Sbjct: 204 YHAKFGIRCDSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHP 261
Query: 145 VCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMR 204
C R+A T R + T T+ + A +TS P+R + +L E LD R
Sbjct: 262 AC---------RQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEI-LDYR 311
Query: 205 VVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPD 264
+ + + D R Y + S G D+ S EG D
Sbjct: 312 DLAA------LPKSKAIYDIDRPDMISYSPYISHSAG----DRQSYGEGDQDDRSYKQCR 361
Query: 265 EPSLAEMGPAN-GLYGSLGEPTQALGRPSGALG 296
S + G + G Y Q RP G
Sbjct: 362 TSSPSSTGSVSLGRYTPTSRSPQHYSRPGSESG 394
Score = 55.8 bits (133), Expect = 7e-08
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVY-CKDDFFKRFGT 93
LC C ++ +L+ D+++H KC C C LAE F + Y C D+ + +GT
Sbjct: 23 LCNTCG-NVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGT 81
Query: 94 KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGD 134
+C +C I V A YH CF C VC+ GD
Sbjct: 82 RCFSCDQFIEGEVV--SALGKTYHPDCFVCAVCRLPFPPGD 120
Score = 35.0 bits (79), Expect = 0.12
Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 108 VRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 151
V R QD +H+ CF C C LA G + + +C DY+
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGG--FFVRQGEYICTLDYQ 76
>gi|194272198 actin binding LIM protein family, member 2 isoform 2
[Homo sapiens]
Length = 611
Score = 87.4 bits (215), Expect = 2e-17
Identities = 77/273 (28%), Positives = 106/273 (38%), Gaps = 25/273 (9%)
Query: 27 ADLRREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDD 86
A L + + C GC I + L ALD+HWH C KC C L S+ YC+ D
Sbjct: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEAD 203
Query: 87 FFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDS--RL 144
+ +FG +C +C+ I T V A + YH C CV C + A G+E YL S
Sbjct: 204 YHAKFGIRCDSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHP 261
Query: 145 VCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMR 204
C R+A T R + T T+ + A +TS P+R + +L E LD R
Sbjct: 262 AC---------RQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEI-LDYR 311
Query: 205 VVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPD 264
+ + + D R Y + S G D+ S EG D
Sbjct: 312 DLAA------LPKSKAIYDIDRPDMISYSPYISHSAG----DRQSYGEGDQDDRSYKQCR 361
Query: 265 EPSLAEMGPAN-GLYGSLGEPTQALGRPSGALG 296
S + G + G Y Q RP G
Sbjct: 362 TSSPSSTGSVSLGRYTPTSRSPQHYSRPGSESG 394
Score = 55.8 bits (133), Expect = 7e-08
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVY-CKDDFFKRFGT 93
LC C ++ +L+ D+++H KC C C LAE F + Y C D+ + +GT
Sbjct: 23 LCNTCG-NVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGT 81
Query: 94 KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGD 134
+C +C I V A YH CF C VC+ GD
Sbjct: 82 RCFSCDQFIEGEVV--SALGKTYHPDCFVCAVCRLPFPPGD 120
Score = 35.0 bits (79), Expect = 0.12
Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 108 VRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 151
V R QD +H+ CF C C LA G + + +C DY+
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGG--FFVRQGEYICTLDYQ 76
>gi|153792514 actin binding LIM protein family, member 2 isoform 6
[Homo sapiens]
Length = 521
Score = 87.0 bits (214), Expect = 3e-17
Identities = 80/273 (29%), Positives = 115/273 (42%), Gaps = 29/273 (10%)
Query: 27 ADLRREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDD 86
A L + + C GC I + L ALD+HWH C KC C L S+ YC+ D
Sbjct: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEAD 203
Query: 87 FFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDS--RL 144
+ +FG +C +C+ I T V A + YH C CV C + A G+E YL S
Sbjct: 204 YHAKFGIRCDSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHP 261
Query: 145 VCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMR 204
C R+A T R + T T+ + A +TS P+R + +L E LD R
Sbjct: 262 AC---------RQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEI-LDYR 311
Query: 205 ----------VVQVWFQNRRAKEKRLKKDAG-RQRWG---QYFRNMKRSRGGSKSDKDSV 250
+ + + + + AG RQ +G Q R+ K+ R S S SV
Sbjct: 312 DLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQCRTSSPSSTGSV 371
Query: 251 QEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGE 283
G+ + S P S ++G GSL +
Sbjct: 372 SLGRYTPTSRS-PQHYSRPAARRSDGEDGSLDQ 403
Score = 55.8 bits (133), Expect = 7e-08
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVY-CKDDFFKRFGT 93
LC C ++ +L+ D+++H KC C C LAE F + Y C D+ + +GT
Sbjct: 23 LCNTCG-NVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGT 81
Query: 94 KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGD 134
+C +C I V A YH CF C VC+ GD
Sbjct: 82 RCFSCDQFIEGEVV--SALGKTYHPDCFVCAVCRLPFPPGD 120
Score = 35.0 bits (79), Expect = 0.12
Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 108 VRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 151
V R QD +H+ CF C C LA G + + +C DY+
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGG--FFVRQGEYICTLDYQ 76
>gi|194272202 actin binding LIM protein family, member 2 isoform 4
[Homo sapiens]
Length = 559
Score = 87.0 bits (214), Expect = 3e-17
Identities = 80/273 (29%), Positives = 115/273 (42%), Gaps = 29/273 (10%)
Query: 27 ADLRREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDD 86
A L + + C GC I + L ALD+HWH C KC C L S+ YC+ D
Sbjct: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEAD 203
Query: 87 FFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDS--RL 144
+ +FG +C +C+ I T V A + YH C CV C + A G+E YL S
Sbjct: 204 YHAKFGIRCDSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHP 261
Query: 145 VCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMR 204
C R+A T R + T T+ + A +TS P+R + +L E LD R
Sbjct: 262 AC---------RQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEI-LDYR 311
Query: 205 ----------VVQVWFQNRRAKEKRLKKDAG-RQRWG---QYFRNMKRSRGGSKSDKDSV 250
+ + + + + AG RQ +G Q R+ K+ R S S SV
Sbjct: 312 DLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQCRTSSPSSTGSV 371
Query: 251 QEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGE 283
G+ + S P S ++G GSL +
Sbjct: 372 SLGRYTPTSRS-PQHYSRPAARRSDGEDGSLDQ 403
Score = 55.8 bits (133), Expect = 7e-08
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVY-CKDDFFKRFGT 93
LC C ++ +L+ D+++H KC C C LAE F + Y C D+ + +GT
Sbjct: 23 LCNTCG-NVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGT 81
Query: 94 KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGD 134
+C +C I V A YH CF C VC+ GD
Sbjct: 82 RCFSCDQFIEGEVV--SALGKTYHPDCFVCAVCRLPFPPGD 120
Score = 35.0 bits (79), Expect = 0.12
Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 108 VRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 151
V R QD +H+ CF C C LA G + + +C DY+
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGG--FFVRQGEYICTLDYQ 76
>gi|194272207 actin binding LIM protein family, member 2 isoform 7
[Homo sapiens]
Length = 470
Score = 86.3 bits (212), Expect = 5e-17
Identities = 59/180 (32%), Positives = 81/180 (45%), Gaps = 14/180 (7%)
Query: 27 ADLRREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDD 86
A L + + C GC I + L ALD+HWH C KC C L S+ YC+ D
Sbjct: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEAD 203
Query: 87 FFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDS--RL 144
+ +FG +C +C+ I T V A + YH C CV C + A G+E YL S
Sbjct: 204 YHAKFGIRCDSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHP 261
Query: 145 VCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMR 204
C R+A T R + T T+ + A +TS P+R + +L E LD R
Sbjct: 262 AC---------RQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEI-LDYR 311
Score = 55.8 bits (133), Expect = 7e-08
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVY-CKDDFFKRFGT 93
LC C ++ +L+ D+++H KC C C LAE F + Y C D+ + +GT
Sbjct: 23 LCNTCG-NVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGT 81
Query: 94 KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGD 134
+C +C I V A YH CF C VC+ GD
Sbjct: 82 RCFSCDQFIEGEVV--SALGKTYHPDCFVCAVCRLPFPPGD 120
Score = 35.0 bits (79), Expect = 0.12
Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 108 VRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 151
V R QD +H+ CF C C LA G + + +C DY+
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGG--FFVRQGEYICTLDYQ 76
>gi|194272204 actin binding LIM protein family, member 2 isoform 5
[Homo sapiens]
Length = 531
Score = 86.3 bits (212), Expect = 5e-17
Identities = 59/180 (32%), Positives = 81/180 (45%), Gaps = 14/180 (7%)
Query: 27 ADLRREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDD 86
A L + + C GC I + L ALD+HWH C KC C L S+ YC+ D
Sbjct: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEAD 203
Query: 87 FFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDS--RL 144
+ +FG +C +C+ I T V A + YH C CV C + A G+E YL S
Sbjct: 204 YHAKFGIRCDSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHP 261
Query: 145 VCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMR 204
C R+A T R + T T+ + A +TS P+R + +L E LD R
Sbjct: 262 AC---------RQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEI-LDYR 311
Score = 55.8 bits (133), Expect = 7e-08
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVY-CKDDFFKRFGT 93
LC C ++ +L+ D+++H KC C C LAE F + Y C D+ + +GT
Sbjct: 23 LCNTCG-NVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGT 81
Query: 94 KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGD 134
+C +C I V A YH CF C VC+ GD
Sbjct: 82 RCFSCDQFIEGEVV--SALGKTYHPDCFVCAVCRLPFPPGD 120
Score = 35.0 bits (79), Expect = 0.12
Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 108 VRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 151
V R QD +H+ CF C C LA G + + +C DY+
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGG--FFVRQGEYICTLDYQ 76
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,516,255
Number of Sequences: 37866
Number of extensions: 1198120
Number of successful extensions: 9325
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 412
Number of HSP's successfully gapped in prelim test: 591
Number of HSP's that attempted gapping in prelim test: 6697
Number of HSP's gapped (non-prelim): 2645
length of query: 402
length of database: 18,247,518
effective HSP length: 105
effective length of query: 297
effective length of database: 14,271,588
effective search space: 4238661636
effective search space used: 4238661636
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.