Guide to the Human Genome
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Name: AFF2 Sequence: fasta or formatted (1311aa) NCBI GI: 87162461
Description:

fragile X mental retardation 2

Referenced in:

Additional Genes in Development

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.6         87           2
 C cysteine            1.1         15           1
 D aspartate           4.4         58           2
 E glutamate           7.1         93           2
 F phenylalanine       2.9         38           2
 G glycine             3.9         51           2
 H histidine           2.3         30           2
 I isoleucine          3.8         50           2
 K lysine              7.9        103           3
 L leucine             7.7        101           2
 M methionine          2.2         29           1
 N asparagine          5.9         77           3
 P proline             9.4        123           3
 Q glutamine           4.3         57           2
 R arginine            4.0         53           3
 S serine             10.7        140           4
 T threonine           8.8        115           8
 V valine              4.3         57           2
 W tryptophan          1.0         13           1
 Y tyrosine            1.6         21           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   fragile X mental retardation 2 
AFF4                  0.232   ALL1 fused gene from 5q31 
AFF3                  0.167   AF4/FMR2 family, member 3 isoform 1 
AFF3                  0.161   AF4/FMR2 family, member 3 isoform 2 
AFF1                  0.117   myeloid/lymphoid or mixed-lineage leukemia trithorax ...
PRG4                  0.022   proteoglycan 4 isoform D 
PRG4                  0.022   proteoglycan 4 isoform C 
PRG4                  0.022   proteoglycan 4 isoform B 
PRG4                  0.022   proteoglycan 4 isoform A 
LOC730474             0.015   PREDICTED: hypothetical protein 
DPCR1                 0.015   diffuse panbronchiolitis critical region 1 protein ...
MUC12                 0.015   PREDICTED: mucin 12 
LOC100294236          0.014   PREDICTED: similar to diffuse panbronchiolitis crit...
NOLC1                 0.014   nucleolar and coiled-body phosphoprotein 1 
LOC730474             0.014   PREDICTED: hypothetical protein, partial 
MUC12                 0.014   PREDICTED: mucin 12, cell surface associated 
MUC17                 0.014   mucin 17 
MDC1                  0.014   mediator of DNA-damage checkpoint 1 
LOC100134138          0.013   PREDICTED: similar to mucin, partial 
LOC100294470          0.011   PREDICTED: hypothetical protein, partial 
TCOF1                 0.011   Treacher Collins-Franceschetti syndrome 1 isoform f...
TCOF1                 0.011   Treacher Collins-Franceschetti syndrome 1 isoform e...
TCOF1                 0.011   Treacher Collins-Franceschetti syndrome 1 isoform d...
TCOF1                 0.011   Treacher Collins-Franceschetti syndrome 1 isoform b ...
TCOF1                 0.011   Treacher Collins-Franceschetti syndrome 1 isoform a ...
TCOF1                 0.011   Treacher Collins-Franceschetti syndrome 1 isoform c ...
NEFH                  0.011   neurofilament, heavy polypeptide 200kDa 
LOC100294335          0.011   PREDICTED: similar to c114 SLIT-like testicular pro...
LOC100294335          0.011   PREDICTED: similar to c114 SLIT-like testicular pro...
MUC6                  0.011   mucin 6, gastric 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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