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Search of human proteins with 71143119
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|71143119 signal-induced proliferation-associated 1 like 3
[Homo sapiens]
(1781 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71143119 signal-induced proliferation-associated 1 like 3 [Ho... 3617 0.0
gi|7662126 signal-induced proliferation-associated 1 like 1 [Hom... 1409 0.0
gi|112421013 signal-induced proliferation-associated 1 like 2 [H... 1330 0.0
gi|206725526 signal-induced proliferation-associated protein 1 [... 614 e-175
gi|206725523 signal-induced proliferation-associated protein 1 [... 614 e-175
gi|156086740 GTPase activating Rap/RanGAP domain-like 4 isoform ... 234 4e-61
gi|156086724 GTPase activating Rap/RanGAP domain-like 4 isoform ... 234 4e-61
gi|224809582 RAP1 GTPase activating protein isoform c [Homo sapi... 224 4e-58
gi|224809578 RAP1 GTPase activating protein isoform a [Homo sapi... 224 4e-58
gi|224809573 RAP1 GTPase activating protein isoform b [Homo sapi... 224 4e-58
gi|207448705 GTPase activating Rap/RanGAP domain-like 3 [Homo sa... 219 2e-56
gi|118600961 akt substrate AS250 [Homo sapiens] 74 1e-12
gi|51230412 GTPase activating Rap/RanGAP domain-like 1 isoform 2... 72 6e-12
gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform 1... 72 6e-12
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 64 1e-09
gi|116256350 tuberous sclerosis 2 isoform 4 [Homo sapiens] 63 2e-09
gi|116256352 tuberous sclerosis 2 isoform 1 [Homo sapiens] 63 2e-09
gi|167412124 tuberous sclerosis 2 isoform 5 [Homo sapiens] 63 2e-09
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 60 2e-08
gi|58530876 melanoma antigen family C, 1 [Homo sapiens] 54 1e-06
gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sap... 53 2e-06
gi|55750053 atrophin-1 [Homo sapiens] 53 3e-06
gi|55750041 atrophin-1 [Homo sapiens] 53 3e-06
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 53 3e-06
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 53 3e-06
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 50 1e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni... 50 3e-05
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 49 3e-05
gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 48 7e-05
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 47 2e-04
>gi|71143119 signal-induced proliferation-associated 1 like 3 [Homo
sapiens]
Length = 1781
Score = 3617 bits (9379), Expect = 0.0
Identities = 1781/1781 (100%), Positives = 1781/1781 (100%)
Query: 1 MTTYRAIPSDGVDLAASCGARVGDVLPGPHTGDYAPLGFWAQNGSMSQPLGESPATATAT 60
MTTYRAIPSDGVDLAASCGARVGDVLPGPHTGDYAPLGFWAQNGSMSQPLGESPATATAT
Sbjct: 1 MTTYRAIPSDGVDLAASCGARVGDVLPGPHTGDYAPLGFWAQNGSMSQPLGESPATATAT 60
Query: 61 ATATTRPSPTTPAMPKMGVRARVADWPPKREALREHSNPSPSQDTDGTKATKMAHSMRSI 120
ATATTRPSPTTPAMPKMGVRARVADWPPKREALREHSNPSPSQDTDGTKATKMAHSMRSI
Sbjct: 61 ATATTRPSPTTPAMPKMGVRARVADWPPKREALREHSNPSPSQDTDGTKATKMAHSMRSI 120
Query: 121 QNGQPPTSTPASSGSKAFHRLSRRRSKDVEFQDGWPRSPGRAFLPLRHRSSSEITLSECD 180
QNGQPPTSTPASSGSKAFHRLSRRRSKDVEFQDGWPRSPGRAFLPLRHRSSSEITLSECD
Sbjct: 121 QNGQPPTSTPASSGSKAFHRLSRRRSKDVEFQDGWPRSPGRAFLPLRHRSSSEITLSECD 180
Query: 181 AEDAGEPRGARHTGALPLFREYGSTSSIDVQGMPEQSFFDILNEFRSEQPDARGCQALTE 240
AEDAGEPRGARHTGALPLFREYGSTSSIDVQGMPEQSFFDILNEFRSEQPDARGCQALTE
Sbjct: 181 AEDAGEPRGARHTGALPLFREYGSTSSIDVQGMPEQSFFDILNEFRSEQPDARGCQALTE 240
Query: 241 LLRADPGPHLMGGGGGAKGDSHNGQPAKDSLLPLQPTKEKEKARKKPARGLGGGDTVDSS 300
LLRADPGPHLMGGGGGAKGDSHNGQPAKDSLLPLQPTKEKEKARKKPARGLGGGDTVDSS
Sbjct: 241 LLRADPGPHLMGGGGGAKGDSHNGQPAKDSLLPLQPTKEKEKARKKPARGLGGGDTVDSS 300
Query: 301 IFRKLRSSKPEGEAGRSPGEADEGRSPPEASRPWVCQKSFAHFDVQSMLFDLNEAAANRV 360
IFRKLRSSKPEGEAGRSPGEADEGRSPPEASRPWVCQKSFAHFDVQSMLFDLNEAAANRV
Sbjct: 301 IFRKLRSSKPEGEAGRSPGEADEGRSPPEASRPWVCQKSFAHFDVQSMLFDLNEAAANRV 360
Query: 361 SVSQRRNTTTGASAASAASAMASLTASRAHSLGGLDPAFTSTEDLNCKENLEQDLGDDNS 420
SVSQRRNTTTGASAASAASAMASLTASRAHSLGGLDPAFTSTEDLNCKENLEQDLGDDNS
Sbjct: 361 SVSQRRNTTTGASAASAASAMASLTASRAHSLGGLDPAFTSTEDLNCKENLEQDLGDDNS 420
Query: 421 NDLLLSCPHFRNEIGGECERNVSFSRASVGSPSSGEGHLAEPALSAYRTNASISVLEVPK 480
NDLLLSCPHFRNEIGGECERNVSFSRASVGSPSSGEGHLAEPALSAYRTNASISVLEVPK
Sbjct: 421 NDLLLSCPHFRNEIGGECERNVSFSRASVGSPSSGEGHLAEPALSAYRTNASISVLEVPK 480
Query: 481 EQQRTQSRPRQYSIEHVDLGARYYQDYFVGKEHANYFGVDEKLGPVAVSIKREKLEDHKE 540
EQQRTQSRPRQYSIEHVDLGARYYQDYFVGKEHANYFGVDEKLGPVAVSIKREKLEDHKE
Sbjct: 481 EQQRTQSRPRQYSIEHVDLGARYYQDYFVGKEHANYFGVDEKLGPVAVSIKREKLEDHKE 540
Query: 541 HGPQYQYRIIFRTRELITLRGSILEDATPTATKHGTGRGLPLKDALEYVIPELNIHCLRL 600
HGPQYQYRIIFRTRELITLRGSILEDATPTATKHGTGRGLPLKDALEYVIPELNIHCLRL
Sbjct: 541 HGPQYQYRIIFRTRELITLRGSILEDATPTATKHGTGRGLPLKDALEYVIPELNIHCLRL 600
Query: 601 ALNTPKVTEQLLKLDEQGLCRKHKVGILYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEK 660
ALNTPKVTEQLLKLDEQGLCRKHKVGILYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEK
Sbjct: 601 ALNTPKVTEQLLKLDEQGLCRKHKVGILYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEK 660
Query: 661 VCLKGFTKYAAQLDVKTDSTGTHSLYTMYQDYEIMFHVSTLLPYTPNNRQQLLRKRHIGN 720
VCLKGFTKYAAQLDVKTDSTGTHSLYTMYQDYEIMFHVSTLLPYTPNNRQQLLRKRHIGN
Sbjct: 661 VCLKGFTKYAAQLDVKTDSTGTHSLYTMYQDYEIMFHVSTLLPYTPNNRQQLLRKRHIGN 720
Query: 721 DIVTIIFQEPGALPFTPKNIRSHFQHVFIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPI 780
DIVTIIFQEPGALPFTPKNIRSHFQHVFIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPI
Sbjct: 721 DIVTIIFQEPGALPFTPKNIRSHFQHVFIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPI 780
Query: 781 PSGTTFRKSDVFRDFLLAKVINAENAAHKSDKFHTMATRTRQEYLKDLAENCVSNTPIDS 840
PSGTTFRKSDVFRDFLLAKVINAENAAHKSDKFHTMATRTRQEYLKDLAENCVSNTPIDS
Sbjct: 781 PSGTTFRKSDVFRDFLLAKVINAENAAHKSDKFHTMATRTRQEYLKDLAENCVSNTPIDS 840
Query: 841 TGKFNLISLTSKKKEKTKARAGAEQHSAGAIAWRVVAQDYAQGVEIDCILGISNEFVVLL 900
TGKFNLISLTSKKKEKTKARAGAEQHSAGAIAWRVVAQDYAQGVEIDCILGISNEFVVLL
Sbjct: 841 TGKFNLISLTSKKKEKTKARAGAEQHSAGAIAWRVVAQDYAQGVEIDCILGISNEFVVLL 900
Query: 901 DLRTKEVVFNCYCGDVIGWTPDSSTLKIFYGRGDHIFLQATEGSVEDIREIVQRLKVMTS 960
DLRTKEVVFNCYCGDVIGWTPDSSTLKIFYGRGDHIFLQATEGSVEDIREIVQRLKVMTS
Sbjct: 901 DLRTKEVVFNCYCGDVIGWTPDSSTLKIFYGRGDHIFLQATEGSVEDIREIVQRLKVMTS 960
Query: 961 GWETVDMTLRRNGLGQLGFHVKYDGTVAEVEDYGFAWQAGLRQGSRLVEICKVAVVTLTH 1020
GWETVDMTLRRNGLGQLGFHVKYDGTVAEVEDYGFAWQAGLRQGSRLVEICKVAVVTLTH
Sbjct: 961 GWETVDMTLRRNGLGQLGFHVKYDGTVAEVEDYGFAWQAGLRQGSRLVEICKVAVVTLTH 1020
Query: 1021 DQMIDLLRTSVTVKVVIIPPFEDGTPRRGWPETYDMNTSEPKTEQESITPGGRPPYRSNA 1080
DQMIDLLRTSVTVKVVIIPPFEDGTPRRGWPETYDMNTSEPKTEQESITPGGRPPYRSNA
Sbjct: 1021 DQMIDLLRTSVTVKVVIIPPFEDGTPRRGWPETYDMNTSEPKTEQESITPGGRPPYRSNA 1080
Query: 1081 PWQWSGPASHNSLPASKWATPTTPGHAQSLSRPLKQTPIVPFRESQPLHSKRPVSFPETP 1140
PWQWSGPASHNSLPASKWATPTTPGHAQSLSRPLKQTPIVPFRESQPLHSKRPVSFPETP
Sbjct: 1081 PWQWSGPASHNSLPASKWATPTTPGHAQSLSRPLKQTPIVPFRESQPLHSKRPVSFPETP 1140
Query: 1141 YTVSPAGADRVPPYRQPSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTSS 1200
YTVSPAGADRVPPYRQPSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTSS
Sbjct: 1141 YTVSPAGADRVPPYRQPSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTSS 1200
Query: 1201 GDSSSGGLTSQESTMERQKPEPLWHVPAQARLSAIAGSSGNKHPSRQDAAGKDSPNRHSK 1260
GDSSSGGLTSQESTMERQKPEPLWHVPAQARLSAIAGSSGNKHPSRQDAAGKDSPNRHSK
Sbjct: 1201 GDSSSGGLTSQESTMERQKPEPLWHVPAQARLSAIAGSSGNKHPSRQDAAGKDSPNRHSK 1260
Query: 1261 GEPQYSSHSSSNTLSSNASSSHSDDRWFDPLDPLEPEQDPLSKGGSSDSGIDTTLYTSSP 1320
GEPQYSSHSSSNTLSSNASSSHSDDRWFDPLDPLEPEQDPLSKGGSSDSGIDTTLYTSSP
Sbjct: 1261 GEPQYSSHSSSNTLSSNASSSHSDDRWFDPLDPLEPEQDPLSKGGSSDSGIDTTLYTSSP 1320
Query: 1321 SCMSLAKAPRPAKPHKPPGSMGLCGGGREAAGRSHHADRRREVSPAPAVAGQSKGYRPKL 1380
SCMSLAKAPRPAKPHKPPGSMGLCGGGREAAGRSHHADRRREVSPAPAVAGQSKGYRPKL
Sbjct: 1321 SCMSLAKAPRPAKPHKPPGSMGLCGGGREAAGRSHHADRRREVSPAPAVAGQSKGYRPKL 1380
Query: 1381 YSSGSSTPTGLAGGSRDPPRQPSDMGSRVGYPAQVYKTASAETPRPSQLAQPSPFQLSAS 1440
YSSGSSTPTGLAGGSRDPPRQPSDMGSRVGYPAQVYKTASAETPRPSQLAQPSPFQLSAS
Sbjct: 1381 YSSGSSTPTGLAGGSRDPPRQPSDMGSRVGYPAQVYKTASAETPRPSQLAQPSPFQLSAS 1440
Query: 1441 VPKSFFSKQPVRNKHPTGWKRTEEPPPRPLPFSDPKKQVDTNTKNVFGQPRLRASLRDLR 1500
VPKSFFSKQPVRNKHPTGWKRTEEPPPRPLPFSDPKKQVDTNTKNVFGQPRLRASLRDLR
Sbjct: 1441 VPKSFFSKQPVRNKHPTGWKRTEEPPPRPLPFSDPKKQVDTNTKNVFGQPRLRASLRDLR 1500
Query: 1501 SPRKNYKSTIEDDLKKLIIMDNLGPEQERDTGQSPQKGLQRTLSDESLCSGRREPSFASP 1560
SPRKNYKSTIEDDLKKLIIMDNLGPEQERDTGQSPQKGLQRTLSDESLCSGRREPSFASP
Sbjct: 1501 SPRKNYKSTIEDDLKKLIIMDNLGPEQERDTGQSPQKGLQRTLSDESLCSGRREPSFASP 1560
Query: 1561 AGLEPGLPSDVLFTSTCAFPSSTLPARRQHQHPHPPVGPGATPAAGSGFPEKKSTISASE 1620
AGLEPGLPSDVLFTSTCAFPSSTLPARRQHQHPHPPVGPGATPAAGSGFPEKKSTISASE
Sbjct: 1561 AGLEPGLPSDVLFTSTCAFPSSTLPARRQHQHPHPPVGPGATPAAGSGFPEKKSTISASE 1620
Query: 1621 LSLADGRDRPLRRLDPGLMPLPDTAAGLEWSSLVNAAKAYEVQRAVSLFSLNDPALSPDI 1680
LSLADGRDRPLRRLDPGLMPLPDTAAGLEWSSLVNAAKAYEVQRAVSLFSLNDPALSPDI
Sbjct: 1621 LSLADGRDRPLRRLDPGLMPLPDTAAGLEWSSLVNAAKAYEVQRAVSLFSLNDPALSPDI 1680
Query: 1681 PPAHSPVHSHLSLERGPPTPRTTPTMSEEPPLDLTGKVYQLEVMLKQLHTDLQKEKQDKV 1740
PPAHSPVHSHLSLERGPPTPRTTPTMSEEPPLDLTGKVYQLEVMLKQLHTDLQKEKQDKV
Sbjct: 1681 PPAHSPVHSHLSLERGPPTPRTTPTMSEEPPLDLTGKVYQLEVMLKQLHTDLQKEKQDKV 1740
Query: 1741 VLQSEVASLRQNNQRLQEESQAASEQLRKFAEIFCREKKEL 1781
VLQSEVASLRQNNQRLQEESQAASEQLRKFAEIFCREKKEL
Sbjct: 1741 VLQSEVASLRQNNQRLQEESQAASEQLRKFAEIFCREKKEL 1781
>gi|7662126 signal-induced proliferation-associated 1 like 1 [Homo
sapiens]
Length = 1804
Score = 1409 bits (3646), Expect = 0.0
Identities = 877/1841 (47%), Positives = 1131/1841 (61%), Gaps = 140/1841 (7%)
Query: 14 LAASCGARVG-DVLPGPHTGDYAPLGFWAQNGSMSQ----PLGESPATATATATATTRPS 68
LA + VG D P HT D+ F +QNGS+ P+G + + T+T
Sbjct: 13 LATDRASVVGTDGTPKVHTDDFYMRRFRSQNGSLGSSVMAPVGPPRSEGSHHITST---- 68
Query: 69 PTTPAMPKMGVRARVADWPPKREALREHSNPSPSQDTDGTKATKMAHSMRSIQNGQPPTS 128
P +PKMGVRAR+ADWPP++E ++E S S +T + + S Q +
Sbjct: 69 ---PGVPKMGVRARIADWPPRKENIKESSRSSQEIETSSCLDSLSSKSSPVSQGSSVSLN 125
Query: 129 TPASSGSKAFHRLSRRRSKDVEFQDG-------WPRSPGRAFLPLRHRSSSEITLSECDA 181
+ S+ K+ + +++ E D +P SP +A +R RS+S+IT+SE D
Sbjct: 126 SNDSAMLKSIQNTLKNKTRPSENMDSRFLMPEAYPSSPRKALRRIRQRSNSDITISELDV 185
Query: 182 EDAGEPRGARHTGALPLFREYGSTSSIDVQGMPEQSFFDILNEFRSEQPDARGCQALTEL 241
+ E + L REYGSTSSID QG +SFFD+L ++ ++ D RG T+L
Sbjct: 186 DSFDECISPTYKTGPSLHREYGSTSSIDKQGTSGESFFDLLKGYKDDKSD-RG-PTPTKL 243
Query: 242 LRADPGPHLMGGGGGAKGDSHNGQPAKDSLLPLQPTKEKEKARKKPARGLGGGDTVDSSI 301
L+ GGG G S + D + + K R+KP + +T DSSI
Sbjct: 244 -----SDFLITGGGKGSGFSLD---VIDGPISQRENLRLFKEREKPLKRRSKSETGDSSI 295
Query: 302 FRKLRSSKPEGEAGRSPGEADEGRSPPEASRPWVCQKSFAHFDVQSMLFDLNEAAANRVS 361
FRKLR++K E E G+S + ++ RS ++ RPW C K FAH+DVQS+LFDLNEA NR +
Sbjct: 296 FRKLRNAKGE-ELGKS-SDLEDNRSE-DSVRPWTCPKCFAHYDVQSILFDLNEAIMNRHN 352
Query: 362 VSQRRNTTTGASAASAASAMASLTASRAHSLGGLDPAFTSTEDLNCKENLEQDLGDDNSN 421
V +RRNTTTGASAA+ AS ++ +HS P STEDLN K +L D GDD SN
Sbjct: 353 VIKRRNTTTGASAAAVASLVSG---PLSHSASFSSP-MGSTEDLNSKGSLSMDQGDDKSN 408
Query: 422 DLLLSCPHFRNEIGGECERNVSFSRASVGSPSSGEGHLAEPALSAYRTNASISVLEVPKE 481
+L++SCP+FRNEIGGE ER +S S+++ GS S E E LS++ TNA ++VLEVPKE
Sbjct: 409 ELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESASFESTLSSHCTNAGVAVLEVPKE 468
Query: 482 QQRTQ-SRPRQYSIEHVDLGARYYQDYFVGKEHANYFGVDEKLGPVAVSIKREKLEDHKE 540
R ++Y +EHVDLGA YY+ +F KEH NYFG DE LGPVAVSI+REK ++ KE
Sbjct: 469 NLVLHLDRVKRYIVEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPDEMKE 528
Query: 541 HGPQYQYRIIFRTRELITLRGSILEDATPTATKHGTGRGLPLKDALEYVIPELNIHCLRL 600
+G Y YRIIFRT EL+TLRGS+LEDA P+ KH T RGLPLK+ LE+V+PELN+ CLRL
Sbjct: 529 NGSPYNYRIIFRTSELMTLRGSVLEDAIPSTAKHSTARGLPLKEVLEHVVPELNVQCLRL 588
Query: 601 ALNTPKVTEQLLKLDEQGLCRKHKVGILYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEK 660
A NTPKVTEQL+KLDEQGL + KVGI+YCKAGQS+EEEMYNNE AGPAFEEFL L+GE+
Sbjct: 589 AFNTPKVTEQLMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGER 648
Query: 661 VCLKGFTKYAAQLDVKTDSTGTHSLYTMYQDYEIMFHVSTLLPYTPNNRQQLLRKRHIGN 720
V LKGF KY AQLD KTDSTGTHSLYT Y+DYEIMFHVST+LPYTPNN+QQLLRKRHIGN
Sbjct: 649 VRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGN 708
Query: 721 DIVTIIFQEPGALPFTPKNIRSHFQHVFIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPI 780
DIVTI+FQEPGA PF+PKNIRSHFQHVF+IVRVHNPC+D+VCYS+AVTRS+D P FGPPI
Sbjct: 709 DIVTIVFQEPGAQPFSPKNIRSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPI 768
Query: 781 PSGTTFRKSDVFRDFLLAKVINAENAAHKSDKFHTMATRTRQEYLKDLAENCVSNTPIDS 840
P G TF KS+VFRDFLLAKVINAENAAHKS+KF MATRTRQEYLKDLAE V+NTPID
Sbjct: 769 PKGVTFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDP 828
Query: 841 TGKFNLISLTSKKKEKTKARAGAEQHSAGAIAWRVVAQDYAQGVEIDCILGISNEFVVLL 900
+GKF ISL SKKKEK+K GAE S GAI W V A+DY + +E+DC+LGISNEF+VL+
Sbjct: 829 SGKFPFISLASKKKEKSKPYPGAELSSMGAIVWAVRAEDYNKAMELDCLLGISNEFIVLI 888
Query: 901 DLRTKEVVFNCYCGDVIGWTPDSSTLKIFYGRGDHIFLQATEGSVEDIREIVQRLKVMTS 960
+ TK VVFNC C DVIGWT ++LKIFY RG+ + + + ++E+I+EIV+RL+ ++
Sbjct: 889 EQETKSVVFNCSCRDVIGWTSTDTSLKIFYERGECVSV-GSFINIEEIKEIVKRLQFVSK 947
Query: 961 GWETVDMTLRRNGLGQLGFHVKYDGTVAEVEDYGFAWQAGLRQGSRLVEICKVAVVTLTH 1020
G E+V+MTLRRNGLGQLGFHV Y+G VA+VE YG+AWQAGLRQGSRLVEICKVAV TL+H
Sbjct: 948 GCESVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSH 1007
Query: 1021 DQMIDLLRTSVTVKVVIIPPFEDGTPRRGWPETYDMNTSEPKTEQESITPGGRPPYRSNA 1080
+QMIDLLRTSVTVKVVIIPP +D TPRR ETY M E K E ++ + P+R+N
Sbjct: 1008 EQMIDLLRTSVTVKVVIIPPHDDCTPRRSCSETYRMPVMEYKM-NEGVSYEFKFPFRNNN 1066
Query: 1081 PWQW-SGPASHNSLPASKWATPTT----PGHAQSLSRPLKQTPIVP---FRESQPLHSKR 1132
WQ + H+ S+ +P T G P ++ +P + +PL +R
Sbjct: 1067 KWQRNASKGPHSPQVPSQVQSPMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPL-ERR 1125
Query: 1133 PVSFPETPYTVSPAGADRVPPYRQPS--GSFSTPGS--ATYVRYKPSPERYTAAPHPLLS 1188
+ TVS R PS S S GS TY R K PE + + S
Sbjct: 1126 LSPGSDIYVTVSSMALARSQCRNSPSNLSSSSDTGSVGGTY-RQKSMPEGFGVSRRSPAS 1184
Query: 1189 LD-PHFSHDGTSSGDSSSGGLTSQESTMER-------------------QKPEPLWHVPA 1228
+D + D SG S+ S++S ++ + EP H+PA
Sbjct: 1185 IDRQNTQSDIGGSGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPA 1244
Query: 1229 QARLSAIAGSSGNKHPSRQDAAGKDSPNRHSKGEPQYSSHSSSNTLSSNASSSHSDDRWF 1288
+++ S + RQD SPN+ + YSSHSSSNTLSSNASS+HSD++W+
Sbjct: 1245 VSKVLPAFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWY 1304
Query: 1289 DPLDPLEPEQDPLS--KGGSSDSGIDTTLY----TSSPSCMSLAKAPR--PAKPHKPP-- 1338
D D E E + + +G S+DSGIDTT Y S+ S + +PR P K P
Sbjct: 1305 DG-DRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLW 1363
Query: 1339 --GSMGLCGGGREAAGRSHHADRRREVSPAPAVAGQSKGYRPKLYSSGSSTPTGLAGGSR 1396
S + R SH DR+ E S + + +S+ L S+
Sbjct: 1364 HSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTF------SIN 1417
Query: 1397 DPPRQPSDMGSRVGYPAQVYKTASAETPR-------PSQLAQP-SPFQLSASVPKSFFSK 1448
D S M SR V+ T++ +P+ PSQLA S S+S P+SF+ +
Sbjct: 1418 DAASHTSTMSSRHSASPVVF-TSARSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPR 1476
Query: 1449 QPVRNKHPTGWKRTEEPPPRPLPFSDPKKQVDTNTKNVFGQPRLRASLRDLR-SPRKNYK 1507
Q +K+ GWK+ E + F D +K+ ++ N RLRAS RDLR SP+ K
Sbjct: 1477 QGATSKYLIGWKK-PEGTINSVGFMDTRKRHQSD-GNEIAHTRLRASTRDLRASPKPTSK 1534
Query: 1508 STIEDDLKKLIIMDNLGPEQER-------DTGQSP-------QKGLQRTLSDESLCSGRR 1553
STIE+DLKKLI +++ PE ++ + QSP ++ L RTLSDES+ + +R
Sbjct: 1535 STIEEDLKKLIDLESPTPESQKSFKFHALSSPQSPFPSTPTSRRALHRTLSDESIYNSQR 1594
Query: 1554 EPSFASPAG-LEPGLPSDVLFTSTCAFPSSTLPARRQHQHPHPPVGPGATPAAGSGFPEK 1612
E F S A L+ LP+DVLF+ST +LP RR P+ G
Sbjct: 1595 EHFFTSRASLLDQALPNDVLFSSTYPSLPKSLPLRR--------------PSYTLGMKSL 1640
Query: 1613 KSTISASELSLADGRDRPLRRL-DPGLMPLPDTAAGLEWSSLVNAAKAYEVQRAVSLFSL 1671
SAS+ SL D ++ + + DPGLMPLPDTAA L+WS+LV+AAKAYEVQRA S F+
Sbjct: 1641 HGEFSASDSSLTDIQETRRQPMPDPGLMPLPDTAADLDWSNLVDAAKAYEVQRA-SFFAA 1699
Query: 1672 NDPALSPDIPPAHSPVHSHLSLERGPPTPRTTPTMSEEPPLDLTGKVYQLEVMLKQLHTD 1731
+D P ++S +L + P + S++ L KV QLE MLK L D
Sbjct: 1700 SDENHRPLSAASNSDQLEDQALAQMKPY-----SSSKDSSPTLASKVDQLEGMLKMLRED 1754
Query: 1732 LQKEKQDKVVLQSEVASLRQNNQRLQEESQAASEQLRKFAE 1772
L+KEK+DK LQ+EV LR++N RLQEESQ AS++L+KF E
Sbjct: 1755 LKKEKEDKAHLQAEVQHLREDNLRLQEESQNASDKLKKFTE 1795
>gi|112421013 signal-induced proliferation-associated 1 like 2 [Homo
sapiens]
Length = 1722
Score = 1330 bits (3443), Expect = 0.0
Identities = 825/1797 (45%), Positives = 1059/1797 (58%), Gaps = 169/1797 (9%)
Query: 33 DYAPLGFWAQNGSMSQPLGESPATATATATATTRPSPTTPAMPKMGVRARVADWPPKREA 92
DY F A NG+M + + + T P+ TPA+PKMGVRARV++WPPK++
Sbjct: 32 DYFARKFKAINGNMGPTTSLNASNSNETGGGG--PANGTPAVPKMGVRARVSEWPPKKDC 89
Query: 93 LREHSNPSPSQDTDGTKATKMAHSMRSIQNGQPPTSTPASSGSKAFHRLSRRRSKDVEFQ 152
+E + + + T + + QNGQ S + + +
Sbjct: 90 SKELTCKALWESRSQTSYESITSVL---QNGQSDQSEGQQDEQLDLDFVEAKYT----IG 142
Query: 153 DGWPRSPGRAFLPLRHRSSSEITLSECDAEDAGEPRGARHTGALPLFREYGSTSSIDVQG 212
D + SP R P+R RS+S++T+S+ DAED + L REYGSTSSID QG
Sbjct: 143 DIFVHSPQRGLHPIRQRSNSDVTISDIDAEDVLDQNAVNPNTGAALHREYGSTSSIDRQG 202
Query: 213 MPEQSFFDILNEFRSEQPDARGCQ--ALTELLRADPG--PHLMGGGGGAKGD--SHNGQP 266
+ ++FF +L +R E D + E R DP P L ++G+ +G
Sbjct: 203 LSGENFFAMLRGYRVENYDHKAMVPFGFPEFFRCDPAISPSLHAAAQISRGEFVRISGLD 262
Query: 267 AKDSLLPLQPTKEKEKARKKPARGLGGGDTVDSSIFRKLRSSKPEGEAGRSPGEADEGRS 326
DS L + ++K R+ + ++V++S+FRKLR+ K E E + E +E R
Sbjct: 263 YVDSALLMGRDRDKPFKRRLKS------ESVETSLFRKLRTVKSEHETFKFTSELEESRL 316
Query: 327 PPEASRPWVCQKSFAHFDVQSMLFDLNEAAANRVSVSQRRNTTTGASAASAASAMASLTA 386
RPW CQ+ FAH+DVQS+LF++NEA A R +V +R+N TTGASAAS T
Sbjct: 317 E-RGIRPWNCQRCFAHYDVQSILFNINEAMATRANVGKRKNITTGASAASQTQMPTGQTG 375
Query: 387 SRAHSLGGLDPAFTSTEDLNCKENLEQDLGDDNSNDLLLSCPHFRNEIGGECERNVSFSR 446
+ LG S EDLN KENL+ D GD SNDL+LSCP+FRNE GGE +R ++ SR
Sbjct: 376 NCESPLG-------SKEDLNSKENLDADEGDGKSNDLVLSCPYFRNETGGEGDRRIALSR 428
Query: 447 ASVGSPSSGEGHLAEPALSAYRTNASISVLEVPKEQQRT-QSRPRQYSIEHVDLGARYYQ 505
A+ S SSGE E +LS++ TNA +SVLEVP+E Q + + ++Y IEH+DLGA YY+
Sbjct: 429 ANSSSFSSGESCSFESSLSSHCTNAGVSVLEVPRENQPIHREKVKRYIIEHIDLGAYYYR 488
Query: 506 DYFVGKEHANYFGVDEKLGPVAVSIKREKLEDHKE-HGPQYQYRIIFRTRELITLRGSIL 564
+F GKEH NYFG+DE LGPVAVSI+REK+ED KE G Q+ YR+ FRT EL TLRG+IL
Sbjct: 489 KFFYGKEHQNYFGIDENLGPVAVSIRREKVEDAKEKEGSQFNYRVAFRTSELTTLRGAIL 548
Query: 565 EDATPTATKHGTGRGLPLKDALEYVIPELNIHCLRLALNTPKVTEQLLKLDEQGLCRKHK 624
EDA P+ +HGT RGLPLK+ LEYVIPEL+I CLR A N+PKV+EQLLKLDEQGL +HK
Sbjct: 549 EDAIPSTARHGTARGLPLKEVLEYVIPELSIQCLRQASNSPKVSEQLLKLDEQGLSFQHK 608
Query: 625 VGILYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEKVCLKGFTKYAAQLDVKTDSTGTHS 684
+GILYCKAGQS+EEEMYNNE AGPAFEEFL L+G++V LKGF+KY AQLD KTDSTGTHS
Sbjct: 609 IGILYCKAGQSTEEEMYNNETAGPAFEEFLDLLGQRVRLKGFSKYRAQLDNKTDSTGTHS 668
Query: 685 LYTMYQDYEIMFHVSTLLPYTPNNRQQLLRKRHIGNDIVTIIFQEPGALPFTPKNIRSHF 744
LYT Y+DYE+MFHVSTLLPY PNNRQQLLRKRHIGNDIVTI+FQEPGALPFTPK+IRSHF
Sbjct: 669 LYTTYKDYELMFHVSTLLPYMPNNRQQLLRKRHIGNDIVTIVFQEPGALPFTPKSIRSHF 728
Query: 745 QHVFIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPIPSGTTFRKSDVFRDFLLAKVINAE 804
QHVF+IV+VHNPCT+NVCYS+ V+RSKD PPFGPPIP G TF KS VFRDFLLAKVINAE
Sbjct: 729 QHVFVIVKVHNPCTENVCYSVGVSRSKDVPPFGPPIPKGVTFPKSAVFRDFLLAKVINAE 788
Query: 805 NAAHKSDKFHTMATRTRQEYLKDLAENCVSNTPIDSTGKFNLISLTSKKKEKTKARAGAE 864
NAAHKS+KF MATRTRQEYLKDLAEN V+ +D++ KF+ I+L +KKKEK K R A
Sbjct: 789 NAAHKSEKFRAMATRTRQEYLKDLAENFVTTATVDTSVKFSFITLGAKKKEKVKPRKDAH 848
Query: 865 QHSAGAIAWRVVAQDYAQGVEIDCILGISNEFVVLLDLRTKEVVFNCYCGDVIGWTPDSS 924
S GAI W V+A+D+ Q +I+C+LGISNEF++L++ +K VVFNC C DVIGWT
Sbjct: 849 LFSIGAIMWHVIARDFGQSADIECLLGISNEFIMLIEKDSKNVVFNCSCRDVIGWTSGLV 908
Query: 925 TLKIFYGRGDHIFLQATEGSVEDIREIVQRLKVMTSGWETVDMTLRRNGLGQLGFHVKYD 984
++K+FY RG+ + L + + EDIREIVQRL ++T G ETV+MTLRRNGLGQLGFHV ++
Sbjct: 909 SIKVFYERGECVLLSSVDNCAEDIREIVQRLVIVTRGCETVEMTLRRNGLGQLGFHVNFE 968
Query: 985 GTVAEVEDYGFAWQAGLRQGSRLVEICKVAVVTLTHDQMIDLLRTSVTVKVVIIPPFEDG 1044
G VA+VE +GFAW+AGLRQGSRLVEICKVAV TLTH+QMIDLLRTSVTVKVVII P +DG
Sbjct: 969 GIVADVEPFGFAWKAGLRQGSRLVEICKVAVATLTHEQMIDLLRTSVTVKVVIIQPHDDG 1028
Query: 1045 TPRRGWPETYDMNTSEPKTEQESITPGGRPPYRSNAPWQWSGPASHNSLPASKWATPTTP 1104
+PRRG E + E K + E + P+R N W PT
Sbjct: 1029 SPRRGCSELCRIPMVEYKLDSEGTPCEYKTPFRRNTTWH---------------RVPTPA 1073
Query: 1105 GHAQSLSRPLKQTPIVPFRESQPLHSKRPVSFP-ETPYTVSPAGADRVPPYRQPSGSFST 1163
S + P+ TP Q L + + P T + R P Q S S
Sbjct: 1074 LQPLSRASPIPGTP--DRLPCQQLLQQAQAAIPRSTSFDRKLPDGTRSSPSNQSSSSDPG 1131
Query: 1164 PGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTSSGDSSSGGLTSQESTMERQK-PEP 1222
PG + R + Y PLL H G SG G +E TME + PE
Sbjct: 1132 PGGSGPWRPQVG---YDGCQSPLL-----LEHQG--SGPLECDGAREREDTMEASRHPET 1181
Query: 1223 LWHVPAQARLSAIAGSSGNKHPSRQDAAGKDSPNRHSK-GEPQYSSHSSSNTLSSNASSS 1281
WH P S + GS + ++D + KDSPN+ S G+ SSHSSSNTLSSN +SS
Sbjct: 1182 KWHGPP----SKVLGSY-KERALQKDGSCKDSPNKLSHIGDKSCSSHSSSNTLSSN-TSS 1235
Query: 1282 HSDDRWFDPLDPLEPEQDPLS--KGGSSDSGIDTTLYTSSPSCMSLAKAPRPAKPHKPPG 1339
+SDD+ F D ++PE L+ KG S+DSGIDT P P G
Sbjct: 1236 NSDDKHFGSGDLMDPELLGLTYIKGASTDSGIDTA----------------PCMPATILG 1279
Query: 1340 SMGLCGGGREAAGRSHHADRRREVS---PAPAVAGQSKGYRPKLYSSGSSTPTGLAGGSR 1396
+ L G R+ +VS PA GY + S S G G
Sbjct: 1280 PVHLAGSRSLIHSRAEQWADAADVSGPDDEPAKLYSVHGYASTI--SAGSAAEGSMGDLS 1337
Query: 1397 DPPRQPSDMGSRVGYPAQVYKTA-SAETPRPSQLAQPSPFQLSASVPKSFFSKQPVRNKH 1455
+ S A K++ S ++ + ++ S Q+ S+ K + +Q NK+
Sbjct: 1338 EISSHSSGSHHSGSPSAHCSKSSGSLDSSKVYIVSHSSGQQVPGSMSKP-YHRQGAVNKY 1396
Query: 1456 PTGWKRTEEPPPRPLPFSDPKKQVDTNTKNVFGQPRLRASLRDLRSPRKNYKSTIED--- 1512
GWK++E PP P++ T ++ + D+ S +++ + D
Sbjct: 1397 VIGWKKSEGSPP-------PEEPEVTECPGMYSE-------MDVMSTATQHQTVVGDAVA 1442
Query: 1513 ---------DLKKLIIMDNLGPEQERDT-----GQSPQKGLQRTLSDESLCSGRREPSFA 1558
D KL++ D+ E+ R SP++ L RTLSDES+CS RR SF
Sbjct: 1443 ETQHVLSKEDFLKLMLPDSPLVEEGRRKFSFYGNLSPRRSLYRTLSDESICSNRRGSSFG 1502
Query: 1559 SPAG--LEPGLPSDVLFTSTCAFPSSTLPARRQHQHPHPPVGPGATPAAGSGFPEKKSTI 1616
S L+ LP+D+LF++T + STLP R HP P +G ++
Sbjct: 1503 SSRSSVLDQALPNDILFSTTPPY-HSTLPPR---AHPAPSMG------------SLRNEF 1546
Query: 1617 SASELSLADGRDRPLRRLDPGLMPLPDTAAGLEWSSLVNAAKAYE--------------- 1661
S+ SL+D + DPGLMPLPDTA GL+W+ LV+AA+A+E
Sbjct: 1547 WFSDGSLSD----KSKCADPGLMPLPDTATGLDWTHLVDAARAFEGLDSDEELGLLCHHT 1602
Query: 1662 ---VQRAVSLFSLNDPALSPDIPPAHSPVHSHLSLERGPPTPRT-TPTMSEEPPLDLTGK 1717
QR S +L D D+ A L L P + + T E P LTGK
Sbjct: 1603 SYLDQRVASFCTLTDMQHGQDLEGA-----QELPLCVDPGSGKEFMDTTGERSPSPLTGK 1657
Query: 1718 VYQLEVMLKQLHTDLQKEKQDKVVLQSEVASLRQNNQRLQEESQAASEQLRKFAEIF 1774
V QLE++L+QL TDL+KEKQDK VLQ+EV LRQ+N RLQEESQ A+ QLRKF E F
Sbjct: 1658 VNQLELILRQLQTDLRKEKQDKAVLQAEVQHLRQDNMRLQEESQTATAQLRKFTEWF 1714
>gi|206725526 signal-induced proliferation-associated protein 1 [Homo
sapiens]
Length = 1042
Score = 614 bits (1583), Expect = e-175
Identities = 374/858 (43%), Positives = 489/858 (56%), Gaps = 112/858 (13%)
Query: 318 PGEADEGRSPPEASRPWVCQKSFAHFDVQSMLFDLNEAAANRVSVSQRRNTTTGASAASA 377
P E E PP W FAH+DVQS+LFD + S S+ + T ++ A
Sbjct: 99 PAEEPEPAFPPVLEPRW-----FAHYDVQSLLFDWAPRSQGMGSHSEASSGTLASAEDQA 153
Query: 378 ASAMASLTASRAHSLGGLDPAFTSTEDLNCKENLEQDLGDDNSNDLLLSCPHFRNEIGGE 437
AS+ DLL P F E+GGE
Sbjct: 154 ASS-----------------------------------------DLLHGAPGFVCELGGE 172
Query: 438 CERNVSFSRASVGSPSSGEGHLAEPALSAYRTNASISVLEVPKEQQRTQSRPRQYSIEHV 497
E +G P+S P + NA++S+LE P Q+R YS+EH
Sbjct: 173 GE-------LGLGGPAS-------PPVPPALPNAAVSILEEP------QNRTSAYSLEHA 212
Query: 498 DLGARYYQDYFVGKEHANYFGVDEKLGPVAVSIKREKLEDHKEHGPQYQYRIIFRTRELI 557
DLGA YY+ YF GKEH N+FG+DE LGPVAVS++RE+ E G + YR+I RT +L
Sbjct: 213 DLGAGYYRKYFYGKEHQNFFGMDESLGPVAVSLRREEKEG-SGGGTLHSYRVIVRTTQLR 271
Query: 558 TLRGSILEDATPTATKHGTGRGLPLKDALEYVIPELNIHCLRLALNTPKVTEQLLKLDEQ 617
TLRG+I EDA P G RGL + LE+V P+L+ CLRL +PKV LL LDEQ
Sbjct: 272 TLRGTISEDALPP----GPPRGLSPRKLLEHVAPQLSPSCLRLGSASPKVPRTLLTLDEQ 327
Query: 618 GLCRKHKVGILYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEKVCLKGFTKYAAQLDVKT 677
L + KVGILYC+AGQ SEEEMYNN+EAGPAF +FL+L+G+ V LKGF Y AQLD KT
Sbjct: 328 VLSFQRKVGILYCRAGQGSEEEMYNNQEAGPAFMQFLTLLGDVVRLKGFESYRAQLDTKT 387
Query: 678 DSTGTHSLYTMYQDYEIMFHVSTLLPYTPNNRQQLLRKRHIGNDIVTIIFQEPGALPFTP 737
DSTGTHSLYT YQD+EIMFHVST+LPYTPNN+QQLLRKRHIGNDIVTI+FQEPG+ PF P
Sbjct: 388 DSTGTHSLYTTYQDHEIMFHVSTMLPYTPNNQQQLLRKRHIGNDIVTIVFQEPGSKPFCP 447
Query: 738 KNIRSHFQHVFIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPIPS-GTTFRKSDVFRDFL 796
IRSHFQHVF++VR H PCT + Y +AV+R++D P FGP +P+ G F + FR FL
Sbjct: 448 TTIRSHFQHVFLVVRAHTPCTPHTTYRVAVSRTQDTPAFGPALPAGGGPFAANADFRAFL 507
Query: 797 LAKVINAENAAHKSDKFHTMATRTRQEYLKDLAENCVSNTPIDSTGKFNLISLTSKKKEK 856
LAK +N E AA + +FH MATRTRQ+YL+DLA N V+ T +DS +F L SL +++
Sbjct: 508 LAKALNGEQAAGHARQFHAMATRTRQQYLQDLATNEVTTTSLDSASRFGLPSLGGRRRAA 567
Query: 857 TKARAGAEQHSAGAIAWRVVAQDYA-----------QGVEIDCILGISNEFVVLLDLRTK 905
+ GAE +AG++ W V A A +G+E+ C+LGIS E +VL+ R
Sbjct: 568 PRG-PGAELQAAGSLVWGVRAAPGARVAAGAQASGPEGIEVPCLLGISAEALVLVAPRDG 626
Query: 906 EVVFNCYCGDVIGWTPDSSTLKIFYGRGDHIFLQATEGSVEDIREIVQRLKVMTSGWETV 965
VVFNC C DV+ WT L +++GRG+ I L+ + + E+V RL++++ G ET
Sbjct: 627 RVVFNCACRDVLAWTFSEQQLDLYHGRGEAITLRFDGSPGQAVGEVVARLQLVSRGCETR 686
Query: 966 DMTLRRNGLGQLGFHVKYDGTVAEVEDYGFAWQAGLRQGSRLVEICKVAVVTLTHDQMID 1025
++ L R+G G+LGF V +G V VE + FA AGLR G+RL+ +C + +L +
Sbjct: 687 ELALPRDGQGRLGFEVDAEGFVTHVERFTFAETAGLRPGARLLRVCGQTLPSLRPEAAAQ 746
Query: 1026 LLRTSVTVKVVIIPPFEDGTPRRGWPETYDMNTSEP---------KTEQESIT------- 1069
LLR++ V V ++PP E G PRR + E Y ++ EP + E + +T
Sbjct: 747 LLRSAPKVCVTVLPPDESGRPRRSFSELYTLSLQEPSRRGAPDPVQDEVQGVTLLPTTKQ 806
Query: 1070 -------PGGRPPYRSN-APWQWSGPASHNSL-PASKWA--TPTTPGHAQSLSRPLKQTP 1118
GG PP + A + S NSL P S + P P L P
Sbjct: 807 LLHLCLQDGGSPPGPGDLAEERTEFLHSQNSLSPRSSLSDEAPVLPNTTPDLLLATTAKP 866
Query: 1119 IVPFRESQ-PLHSKRPVS 1135
VP +S+ PL RP S
Sbjct: 867 SVPSADSETPLTQDRPGS 884
Score = 70.1 bits (170), Expect = 2e-11
Identities = 73/215 (33%), Positives = 95/215 (44%), Gaps = 12/215 (5%)
Query: 1562 GLEPGLPSDVLFTSTCAFPSSTLPARRQHQHPHPPVGPGATPAAGSGFPEKKSTISA-SE 1620
G PG P D+ T S + R PV P TP K S SA SE
Sbjct: 816 GSPPG-PGDLAEERTEFLHSQNSLSPRSSLSDEAPVLPNTTPDLLLATTAKPSVPSADSE 874
Query: 1621 LSLADGRD-RPLRRLDPGLMPLPDTAAGLEWSSLVNAAKAYEVQRAVSLFSLNDP--ALS 1677
L R P D G P P+ A +L + +L D A+S
Sbjct: 875 TPLTQDRPGSPSGSEDKG-NPAPELRASFLPRTLSLRNSISRIMSEAGSGTLEDEWQAIS 933
Query: 1678 PDIPPAHSPVHSHLSLERGP----PTPRTTPTMSEEP-PLDLTGKVYQLEVMLKQLHTDL 1732
+I + + LS E P P+ TP EP P +L+ KV LE ML++L DL
Sbjct: 934 -EIASTCNTILESLSREGQPIPESGDPKGTPKSDAEPEPGNLSEKVSHLESMLRKLQEDL 992
Query: 1733 QKEKQDKVVLQSEVASLRQNNQRLQEESQAASEQL 1767
QKEK D+ L+ EV SLR NN+RLQ ES++A+ +L
Sbjct: 993 QKEKADRAALEEEVRSLRHNNRRLQAESESAATRL 1027
>gi|206725523 signal-induced proliferation-associated protein 1 [Homo
sapiens]
Length = 1042
Score = 614 bits (1583), Expect = e-175
Identities = 374/858 (43%), Positives = 489/858 (56%), Gaps = 112/858 (13%)
Query: 318 PGEADEGRSPPEASRPWVCQKSFAHFDVQSMLFDLNEAAANRVSVSQRRNTTTGASAASA 377
P E E PP W FAH+DVQS+LFD + S S+ + T ++ A
Sbjct: 99 PAEEPEPAFPPVLEPRW-----FAHYDVQSLLFDWAPRSQGMGSHSEASSGTLASAEDQA 153
Query: 378 ASAMASLTASRAHSLGGLDPAFTSTEDLNCKENLEQDLGDDNSNDLLLSCPHFRNEIGGE 437
AS+ DLL P F E+GGE
Sbjct: 154 ASS-----------------------------------------DLLHGAPGFVCELGGE 172
Query: 438 CERNVSFSRASVGSPSSGEGHLAEPALSAYRTNASISVLEVPKEQQRTQSRPRQYSIEHV 497
E +G P+S P + NA++S+LE P Q+R YS+EH
Sbjct: 173 GE-------LGLGGPAS-------PPVPPALPNAAVSILEEP------QNRTSAYSLEHA 212
Query: 498 DLGARYYQDYFVGKEHANYFGVDEKLGPVAVSIKREKLEDHKEHGPQYQYRIIFRTRELI 557
DLGA YY+ YF GKEH N+FG+DE LGPVAVS++RE+ E G + YR+I RT +L
Sbjct: 213 DLGAGYYRKYFYGKEHQNFFGMDESLGPVAVSLRREEKEG-SGGGTLHSYRVIVRTTQLR 271
Query: 558 TLRGSILEDATPTATKHGTGRGLPLKDALEYVIPELNIHCLRLALNTPKVTEQLLKLDEQ 617
TLRG+I EDA P G RGL + LE+V P+L+ CLRL +PKV LL LDEQ
Sbjct: 272 TLRGTISEDALPP----GPPRGLSPRKLLEHVAPQLSPSCLRLGSASPKVPRTLLTLDEQ 327
Query: 618 GLCRKHKVGILYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEKVCLKGFTKYAAQLDVKT 677
L + KVGILYC+AGQ SEEEMYNN+EAGPAF +FL+L+G+ V LKGF Y AQLD KT
Sbjct: 328 VLSFQRKVGILYCRAGQGSEEEMYNNQEAGPAFMQFLTLLGDVVRLKGFESYRAQLDTKT 387
Query: 678 DSTGTHSLYTMYQDYEIMFHVSTLLPYTPNNRQQLLRKRHIGNDIVTIIFQEPGALPFTP 737
DSTGTHSLYT YQD+EIMFHVST+LPYTPNN+QQLLRKRHIGNDIVTI+FQEPG+ PF P
Sbjct: 388 DSTGTHSLYTTYQDHEIMFHVSTMLPYTPNNQQQLLRKRHIGNDIVTIVFQEPGSKPFCP 447
Query: 738 KNIRSHFQHVFIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPIPS-GTTFRKSDVFRDFL 796
IRSHFQHVF++VR H PCT + Y +AV+R++D P FGP +P+ G F + FR FL
Sbjct: 448 TTIRSHFQHVFLVVRAHTPCTPHTTYRVAVSRTQDTPAFGPALPAGGGPFAANADFRAFL 507
Query: 797 LAKVINAENAAHKSDKFHTMATRTRQEYLKDLAENCVSNTPIDSTGKFNLISLTSKKKEK 856
LAK +N E AA + +FH MATRTRQ+YL+DLA N V+ T +DS +F L SL +++
Sbjct: 508 LAKALNGEQAAGHARQFHAMATRTRQQYLQDLATNEVTTTSLDSASRFGLPSLGGRRRAA 567
Query: 857 TKARAGAEQHSAGAIAWRVVAQDYA-----------QGVEIDCILGISNEFVVLLDLRTK 905
+ GAE +AG++ W V A A +G+E+ C+LGIS E +VL+ R
Sbjct: 568 PRG-PGAELQAAGSLVWGVRAAPGARVAAGAQASGPEGIEVPCLLGISAEALVLVAPRDG 626
Query: 906 EVVFNCYCGDVIGWTPDSSTLKIFYGRGDHIFLQATEGSVEDIREIVQRLKVMTSGWETV 965
VVFNC C DV+ WT L +++GRG+ I L+ + + E+V RL++++ G ET
Sbjct: 627 RVVFNCACRDVLAWTFSEQQLDLYHGRGEAITLRFDGSPGQAVGEVVARLQLVSRGCETR 686
Query: 966 DMTLRRNGLGQLGFHVKYDGTVAEVEDYGFAWQAGLRQGSRLVEICKVAVVTLTHDQMID 1025
++ L R+G G+LGF V +G V VE + FA AGLR G+RL+ +C + +L +
Sbjct: 687 ELALPRDGQGRLGFEVDAEGFVTHVERFTFAETAGLRPGARLLRVCGQTLPSLRPEAAAQ 746
Query: 1026 LLRTSVTVKVVIIPPFEDGTPRRGWPETYDMNTSEP---------KTEQESIT------- 1069
LLR++ V V ++PP E G PRR + E Y ++ EP + E + +T
Sbjct: 747 LLRSAPKVCVTVLPPDESGRPRRSFSELYTLSLQEPSRRGAPDPVQDEVQGVTLLPTTKQ 806
Query: 1070 -------PGGRPPYRSN-APWQWSGPASHNSL-PASKWA--TPTTPGHAQSLSRPLKQTP 1118
GG PP + A + S NSL P S + P P L P
Sbjct: 807 LLHLCLQDGGSPPGPGDLAEERTEFLHSQNSLSPRSSLSDEAPVLPNTTPDLLLATTAKP 866
Query: 1119 IVPFRESQ-PLHSKRPVS 1135
VP +S+ PL RP S
Sbjct: 867 SVPSADSETPLTQDRPGS 884
Score = 70.1 bits (170), Expect = 2e-11
Identities = 73/215 (33%), Positives = 95/215 (44%), Gaps = 12/215 (5%)
Query: 1562 GLEPGLPSDVLFTSTCAFPSSTLPARRQHQHPHPPVGPGATPAAGSGFPEKKSTISA-SE 1620
G PG P D+ T S + R PV P TP K S SA SE
Sbjct: 816 GSPPG-PGDLAEERTEFLHSQNSLSPRSSLSDEAPVLPNTTPDLLLATTAKPSVPSADSE 874
Query: 1621 LSLADGRD-RPLRRLDPGLMPLPDTAAGLEWSSLVNAAKAYEVQRAVSLFSLNDP--ALS 1677
L R P D G P P+ A +L + +L D A+S
Sbjct: 875 TPLTQDRPGSPSGSEDKG-NPAPELRASFLPRTLSLRNSISRIMSEAGSGTLEDEWQAIS 933
Query: 1678 PDIPPAHSPVHSHLSLERGP----PTPRTTPTMSEEP-PLDLTGKVYQLEVMLKQLHTDL 1732
+I + + LS E P P+ TP EP P +L+ KV LE ML++L DL
Sbjct: 934 -EIASTCNTILESLSREGQPIPESGDPKGTPKSDAEPEPGNLSEKVSHLESMLRKLQEDL 992
Query: 1733 QKEKQDKVVLQSEVASLRQNNQRLQEESQAASEQL 1767
QKEK D+ L+ EV SLR NN+RLQ ES++A+ +L
Sbjct: 993 QKEKADRAALEEEVRSLRHNNRRLQAESESAATRL 1027
>gi|156086740 GTPase activating Rap/RanGAP domain-like 4 isoform 2
[Homo sapiens]
Length = 715
Score = 234 bits (598), Expect = 4e-61
Identities = 144/389 (37%), Positives = 210/389 (53%), Gaps = 27/389 (6%)
Query: 452 PSSGEGHLAEPALSAYRTNASISVLEVPKEQQRTQSRPRQYSIEHVDLG-ARYYQDYFVG 510
P G + +P T+ S+ E E++ P + + G AR Y+ +F+G
Sbjct: 92 PQFGGYWIEDPENVGTPTSLGSSICE---EEEEDNLSPNTFGYKLECKGEARAYRRHFLG 148
Query: 511 KEHANYFGVDEKLGPVAVSIKREKLEDHKEHGPQYQYRIIFRTRELITLRGSILEDATPT 570
K+H N++ LG + +S+K E+ E G +Y R+I R++ + + P
Sbjct: 149 KDHLNFYCTGSSLGNLILSVKCEEAE-----GIEY-LRVILRSKL------KTVHERIPL 196
Query: 571 ATKHGTGRGLPLKDALEYVIPELNIHCLRLALNT---PKVTEQLLKLDEQGLCRKHKVGI 627
A GL ++ + + L N PK ++ ++ DE + K G+
Sbjct: 197 A-------GLSKLPSVPQIAKAFCDDAVGLRFNPVLYPKASQMIVSYDEHEVNNTFKFGV 249
Query: 628 LYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEKVCLKGFTKYAAQLDVKTDSTGTHSLYT 687
+Y KA Q+ EEE++ N E PAF+EFL L+G+ + L+ F + LDV TG S+YT
Sbjct: 250 IYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYT 309
Query: 688 MYQDYEIMFHVSTLLPYTPNNRQQLLRKRHIGNDIVTIIFQEPGALPFTPKNIRSHFQHV 747
++D EIMFHVST LP+T + QQL RKRHIGNDIV IIFQE PF P I S+F H
Sbjct: 310 TFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIVAIIFQEENT-PFVPDMIASNFLHA 368
Query: 748 FIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPIPSGTTFRKSDVFRDFLLAKVINAENAA 807
+I+V+V P T+ Y ++VT +D P FGPP+PS F+K FR+FLL K+ NAENA
Sbjct: 369 YIVVQVETPGTETPSYKVSVTAREDVPTFGPPLPSPPVFQKGPEFREFLLTKLTNAENAC 428
Query: 808 HKSDKFHTMATRTRQEYLKDLAENCVSNT 836
KSDKF + RTR L +L + ++T
Sbjct: 429 CKSDKFAKLEDRTRAALLDNLHDELHAHT 457
Score = 32.3 bits (72), Expect = 4.2
Identities = 60/249 (24%), Positives = 93/249 (37%), Gaps = 25/249 (10%)
Query: 1041 FEDGTPRRGWPETYDMNTSEPKTEQESITPGGRPPYRSNAPWQWSGPASHNSLPASK--W 1098
FE+G G+ E++ E++ G + + P SG SHNS+ +K +
Sbjct: 470 FENGG-HGGFLESFKRAIRVRSHSMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTF 528
Query: 1099 ATPTTPGHAQSLSR-PLKQTP-----IVPFRESQPLHSKRPVSFPETPYTVSPAGADRVP 1152
+ P ++ SR P+K+ + E Q R S TP T P G
Sbjct: 529 SPPVVAATVKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKT--PDGGHSSQ 586
Query: 1153 PYRQPSGSFSTPGSATYVRYKPSP-------ERYTAAPHPLLSLDPHFSHDGTSSGDSSS 1205
+ S + S P S K P R + S + +G + + S
Sbjct: 587 EIK--SETSSNPSSPEICPNKEKPFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDS 644
Query: 1206 GGLTSQESTMERQKPEPLWHVPAQARLSAIAGSSGN---KHPSRQDAAGKDSPNRHSKGE 1262
GG SQ ST K E + P+ + S G++ S DA ++SP + K
Sbjct: 645 GG--SQPSTTSPFKQEVFVYSPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPRSNLKFR 702
Query: 1263 PQYSSHSSS 1271
SH+SS
Sbjct: 703 FDKLSHASS 711
>gi|156086724 GTPase activating Rap/RanGAP domain-like 4 isoform 1
[Homo sapiens]
Length = 730
Score = 234 bits (598), Expect = 4e-61
Identities = 144/389 (37%), Positives = 210/389 (53%), Gaps = 27/389 (6%)
Query: 452 PSSGEGHLAEPALSAYRTNASISVLEVPKEQQRTQSRPRQYSIEHVDLG-ARYYQDYFVG 510
P G + +P T+ S+ E E++ P + + G AR Y+ +F+G
Sbjct: 107 PQFGGYWIEDPENVGTPTSLGSSICE---EEEEDNLSPNTFGYKLECKGEARAYRRHFLG 163
Query: 511 KEHANYFGVDEKLGPVAVSIKREKLEDHKEHGPQYQYRIIFRTRELITLRGSILEDATPT 570
K+H N++ LG + +S+K E+ E G +Y R+I R++ + + P
Sbjct: 164 KDHLNFYCTGSSLGNLILSVKCEEAE-----GIEY-LRVILRSKL------KTVHERIPL 211
Query: 571 ATKHGTGRGLPLKDALEYVIPELNIHCLRLALNT---PKVTEQLLKLDEQGLCRKHKVGI 627
A GL ++ + + L N PK ++ ++ DE + K G+
Sbjct: 212 A-------GLSKLPSVPQIAKAFCDDAVGLRFNPVLYPKASQMIVSYDEHEVNNTFKFGV 264
Query: 628 LYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEKVCLKGFTKYAAQLDVKTDSTGTHSLYT 687
+Y KA Q+ EEE++ N E PAF+EFL L+G+ + L+ F + LDV TG S+YT
Sbjct: 265 IYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYT 324
Query: 688 MYQDYEIMFHVSTLLPYTPNNRQQLLRKRHIGNDIVTIIFQEPGALPFTPKNIRSHFQHV 747
++D EIMFHVST LP+T + QQL RKRHIGNDIV IIFQE PF P I S+F H
Sbjct: 325 TFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIVAIIFQEENT-PFVPDMIASNFLHA 383
Query: 748 FIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPIPSGTTFRKSDVFRDFLLAKVINAENAA 807
+I+V+V P T+ Y ++VT +D P FGPP+PS F+K FR+FLL K+ NAENA
Sbjct: 384 YIVVQVETPGTETPSYKVSVTAREDVPTFGPPLPSPPVFQKGPEFREFLLTKLTNAENAC 443
Query: 808 HKSDKFHTMATRTRQEYLKDLAENCVSNT 836
KSDKF + RTR L +L + ++T
Sbjct: 444 CKSDKFAKLEDRTRAALLDNLHDELHAHT 472
Score = 32.3 bits (72), Expect = 4.2
Identities = 60/249 (24%), Positives = 93/249 (37%), Gaps = 25/249 (10%)
Query: 1041 FEDGTPRRGWPETYDMNTSEPKTEQESITPGGRPPYRSNAPWQWSGPASHNSLPASK--W 1098
FE+G G+ E++ E++ G + + P SG SHNS+ +K +
Sbjct: 485 FENGG-HGGFLESFKRAIRVRSHSMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTF 543
Query: 1099 ATPTTPGHAQSLSR-PLKQTP-----IVPFRESQPLHSKRPVSFPETPYTVSPAGADRVP 1152
+ P ++ SR P+K+ + E Q R S TP T P G
Sbjct: 544 SPPVVAATVKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKT--PDGGHSSQ 601
Query: 1153 PYRQPSGSFSTPGSATYVRYKPSP-------ERYTAAPHPLLSLDPHFSHDGTSSGDSSS 1205
+ S + S P S K P R + S + +G + + S
Sbjct: 602 EIK--SETSSNPSSPEICPNKEKPFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDS 659
Query: 1206 GGLTSQESTMERQKPEPLWHVPAQARLSAIAGSSGN---KHPSRQDAAGKDSPNRHSKGE 1262
GG SQ ST K E + P+ + S G++ S DA ++SP + K
Sbjct: 660 GG--SQPSTTSPFKQEVFVYSPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPRSNLKFR 717
Query: 1263 PQYSSHSSS 1271
SH+SS
Sbjct: 718 FDKLSHASS 726
>gi|224809582 RAP1 GTPase activating protein isoform c [Homo
sapiens]
Length = 663
Score = 224 bits (572), Expect = 4e-58
Identities = 128/338 (37%), Positives = 186/338 (55%), Gaps = 33/338 (9%)
Query: 501 ARYYQDYFVGKEHANYFGVDEKLGPVAVSIKREKLEDHKEHGPQYQYRIIFRTRELITLR 560
AR Y+ +F+GKEH NY+ +D LG + S+K + + G Q R++ RT+
Sbjct: 87 ARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDVI------GDQEHLRLLLRTK------ 134
Query: 561 GSILEDATPTATKHGTGRGLPLKDALEY--VIPELNIHCLRLALNT------PKVTEQLL 612
T H +P+ E+ V+ + C + ++ PK + ++
Sbjct: 135 ---------CRTYHDV---IPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRLIV 182
Query: 613 KLDEQGLCRKHKVGILYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEKVCLKGFTKYAAQ 672
DE + K G++Y K GQ+SEEE+++ E PAF EFL +G+KV L+ F +
Sbjct: 183 TFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFRGG 242
Query: 673 LDVKTDSTGTHSLYTMYQDYEIMFHVSTLLPYTPNNRQQLLRKRHIGNDIVTIIFQEPGA 732
LDV TGT S+Y +++ EIMFHVST LPYT + QQL RKRHIGNDIV ++FQ+
Sbjct: 243 LDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDENT 302
Query: 733 LPFTPKNIRSHFQHVFIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPIPSGTTFRKSDVF 792
PF P I S+F H +++V+ D Y ++VT D P FGPP+P FRK F
Sbjct: 303 -PFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPEF 361
Query: 793 RDFLLAKVINAENAAHKSDKFHTMATRTRQEYLKDLAE 830
++FLL K+INAE A +K++KF + RTR L+ L E
Sbjct: 362 QEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYE 399
>gi|224809578 RAP1 GTPase activating protein isoform a [Homo
sapiens]
Length = 727
Score = 224 bits (572), Expect = 4e-58
Identities = 128/338 (37%), Positives = 186/338 (55%), Gaps = 33/338 (9%)
Query: 501 ARYYQDYFVGKEHANYFGVDEKLGPVAVSIKREKLEDHKEHGPQYQYRIIFRTRELITLR 560
AR Y+ +F+GKEH NY+ +D LG + S+K + + G Q R++ RT+
Sbjct: 151 ARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDVI------GDQEHLRLLLRTK------ 198
Query: 561 GSILEDATPTATKHGTGRGLPLKDALEY--VIPELNIHCLRLALNT------PKVTEQLL 612
T H +P+ E+ V+ + C + ++ PK + ++
Sbjct: 199 ---------CRTYHDV---IPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRLIV 246
Query: 613 KLDEQGLCRKHKVGILYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEKVCLKGFTKYAAQ 672
DE + K G++Y K GQ+SEEE+++ E PAF EFL +G+KV L+ F +
Sbjct: 247 TFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFRGG 306
Query: 673 LDVKTDSTGTHSLYTMYQDYEIMFHVSTLLPYTPNNRQQLLRKRHIGNDIVTIIFQEPGA 732
LDV TGT S+Y +++ EIMFHVST LPYT + QQL RKRHIGNDIV ++FQ+
Sbjct: 307 LDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDENT 366
Query: 733 LPFTPKNIRSHFQHVFIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPIPSGTTFRKSDVF 792
PF P I S+F H +++V+ D Y ++VT D P FGPP+P FRK F
Sbjct: 367 -PFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPEF 425
Query: 793 RDFLLAKVINAENAAHKSDKFHTMATRTRQEYLKDLAE 830
++FLL K+INAE A +K++KF + RTR L+ L E
Sbjct: 426 QEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYE 463
>gi|224809573 RAP1 GTPase activating protein isoform b [Homo
sapiens]
Length = 681
Score = 224 bits (572), Expect = 4e-58
Identities = 128/338 (37%), Positives = 186/338 (55%), Gaps = 33/338 (9%)
Query: 501 ARYYQDYFVGKEHANYFGVDEKLGPVAVSIKREKLEDHKEHGPQYQYRIIFRTRELITLR 560
AR Y+ +F+GKEH NY+ +D LG + S+K + + G Q R++ RT+
Sbjct: 87 ARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDVI------GDQEHLRLLLRTK------ 134
Query: 561 GSILEDATPTATKHGTGRGLPLKDALEY--VIPELNIHCLRLALNT------PKVTEQLL 612
T H +P+ E+ V+ + C + ++ PK + ++
Sbjct: 135 ---------CRTYHDV---IPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRLIV 182
Query: 613 KLDEQGLCRKHKVGILYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEKVCLKGFTKYAAQ 672
DE + K G++Y K GQ+SEEE+++ E PAF EFL +G+KV L+ F +
Sbjct: 183 TFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFRGG 242
Query: 673 LDVKTDSTGTHSLYTMYQDYEIMFHVSTLLPYTPNNRQQLLRKRHIGNDIVTIIFQEPGA 732
LDV TGT S+Y +++ EIMFHVST LPYT + QQL RKRHIGNDIV ++FQ+
Sbjct: 243 LDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDENT 302
Query: 733 LPFTPKNIRSHFQHVFIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPIPSGTTFRKSDVF 792
PF P I S+F H +++V+ D Y ++VT D P FGPP+P FRK F
Sbjct: 303 -PFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPEF 361
Query: 793 RDFLLAKVINAENAAHKSDKFHTMATRTRQEYLKDLAE 830
++FLL K+INAE A +K++KF + RTR L+ L E
Sbjct: 362 QEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYE 399
>gi|207448705 GTPase activating Rap/RanGAP domain-like 3 [Homo
sapiens]
Length = 1013
Score = 219 bits (557), Expect = 2e-56
Identities = 128/343 (37%), Positives = 195/343 (56%), Gaps = 26/343 (7%)
Query: 494 IEHVDLGARYYQDYFVGKEHANYFGVDEKLGPVAVSIKREKLEDHKEHGPQYQYRIIFRT 553
+E+ + R+Y YF+G+ H NY G D + P +S+ + + + PQY+ I++R
Sbjct: 89 LENPEYHTRWYFKYFLGQVHQNYIGNDAEKSPFFLSVTLS--DQNNQRVPQYR-AILWRK 145
Query: 554 RELITLRGSILEDATPTATKHGTGRGLPLKDALEYVIPELNIHCLRLA---LNTPKVTEQ 610
T I +PT T +++ ++ +N+ + P++ +
Sbjct: 146 ----TGTQKICLPYSPTKTL-----------SVKSILSAMNLDKFEKGPREIFHPEIQKD 190
Query: 611 LLKLDEQGLCRKHKVGILYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEKVCLKGFTKYA 670
LL L+EQ K G+L+ K GQ +++EM++NE F++FL+L+G+ + LKG+T Y
Sbjct: 191 LLVLEEQEGSVNFKFGVLFAKDGQLTDDEMFSNEIGSEPFQKFLNLLGDTITLKGWTGYR 250
Query: 671 AQLDVKTDSTGTHSLYTMYQDYEIMFHVSTLLPYTPNNRQQLLRKRHIGNDIVTIIFQ-- 728
LD K D+TG HS+YT+YQ +EIMFHVST+LPY+ N+QQ+ RKRHIGNDIVTI+FQ
Sbjct: 251 GGLDTKNDTTGIHSVYTVYQGHEIMFHVSTMLPYSKENKQQVERKRHIGNDIVTIVFQEG 310
Query: 729 EPGALPFTPKNIRSHFQHVFIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPIPSGTTFRK 788
E + F P IRSHF H+F +VR +N DN Y + + + P FGPP+P+ F
Sbjct: 311 EESSPAFKPSMIRSHFTHIFALVR-YNQQNDN--YRLKIFSEESVPLFGPPLPTPPVFTD 367
Query: 789 SDVFRDFLLAKVINAENAAHKSDKFHTMATRTRQEYLKDLAEN 831
FRDFLL K+IN E A ++ F RT ++ L ++
Sbjct: 368 HQEFRDFLLVKLINGEKATLETPTFAQKRRRTLDMLIRSLHQD 410
>gi|118600961 akt substrate AS250 [Homo sapiens]
Length = 1873
Score = 73.9 bits (180), Expect = 1e-12
Identities = 64/239 (26%), Positives = 106/239 (44%), Gaps = 14/239 (5%)
Query: 594 NIHCLRLALNTPKVTEQLLKLDEQGLCRKHKVGILYCKAGQSSEEEMYNNEEAGPAFEEF 653
N H L+ K+ +L LD + HK+ + Y GQ + + +NE A+E+F
Sbjct: 1621 NFHLLK---KNSKLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILSNERGSQAYEDF 1677
Query: 654 LSLIGEKVCLKGFTKYAAQLDVKTDSTGTHSLYTMYQDYEIMFHVSTLLPYTPNNRQQLL 713
++ +G +V L + L + STG + Y E++FHVST +P ++ L
Sbjct: 1678 VAGLGWEVDLSTHCGFMGGLQ-RNGSTGQTAPYYATSTVEVIFHVSTRMP--SDSDDSLT 1734
Query: 714 RK-RHIGNDIVTIIFQEPGALPFTPKNIRSHFQHVFIIVRVHNPCTDNVCYSMAVTRSKD 772
+K RH+GND V I++ E + + I + F V II+ N + +A+T+ +
Sbjct: 1735 KKLRHLGNDEVHIVWSE-HSRDYRRGIIPTAFGDVSIIIYP----MKNHMFFIAITKKPE 1789
Query: 773 APPFGPPIPSGTTFRKSDVFRDFLLAKVINAENAAHKSDKFHTMATRTRQEYLKDLAEN 831
P FGP K + + A INA A + R YL+ + +N
Sbjct: 1790 VPFFGPLFDGAIVSGK--LLPSLVCATCINASRAVKCLIPLYQSFYEERALYLEAIIQN 1846
>gi|51230412 GTPase activating Rap/RanGAP domain-like 1 isoform 2
[Homo sapiens]
Length = 2083
Score = 71.6 bits (174), Expect = 6e-12
Identities = 60/235 (25%), Positives = 101/235 (42%), Gaps = 11/235 (4%)
Query: 606 KVTEQLLKLDEQGLCRKHKVGILYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEKVCLKG 665
K+ +L LD + HK+ + Y GQ + + N A+E+F++ +G +V L
Sbjct: 1791 KLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTN 1850
Query: 666 FTKYAAQLDVKTDSTGTHSLYTMYQDYEIMFHVSTLLPYTPNNRQQLLRK-RHIGNDIVT 724
+ L K STG + Y E++FHVST +P ++ L +K RH+GND V
Sbjct: 1851 HCGFMGGLQ-KNKSTGLTTPYFATSTVEVIFHVSTRMP--SDSDDSLTKKLRHLGNDEVH 1907
Query: 725 IIFQEPGALPFTPKNIRSHFQHVFIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPIPSGT 784
I++ E + I + F V I++ N +S+ + + + P FGP
Sbjct: 1908 IVWSE-HTRDYRRGIIPTEFGDVLIVIYP----MKNHMFSIQIMKKPEVPFFGPLFDGAI 1962
Query: 785 TFRKSDVFRDFLLAKVINAENAAHKSDKFHTMATRTRQEYLKDLAENCVSNTPID 839
K V + A INA A + R YL+ + ++ + T +
Sbjct: 1963 VNGK--VLPIMVRATAINASRALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFE 2015
>gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform 1
[Homo sapiens]
Length = 2036
Score = 71.6 bits (174), Expect = 6e-12
Identities = 60/235 (25%), Positives = 101/235 (42%), Gaps = 11/235 (4%)
Query: 606 KVTEQLLKLDEQGLCRKHKVGILYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEKVCLKG 665
K+ +L LD + HK+ + Y GQ + + N A+E+F++ +G +V L
Sbjct: 1791 KLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTN 1850
Query: 666 FTKYAAQLDVKTDSTGTHSLYTMYQDYEIMFHVSTLLPYTPNNRQQLLRK-RHIGNDIVT 724
+ L K STG + Y E++FHVST +P ++ L +K RH+GND V
Sbjct: 1851 HCGFMGGLQ-KNKSTGLTTPYFATSTVEVIFHVSTRMP--SDSDDSLTKKLRHLGNDEVH 1907
Query: 725 IIFQEPGALPFTPKNIRSHFQHVFIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPIPSGT 784
I++ E + I + F V I++ N +S+ + + + P FGP
Sbjct: 1908 IVWSE-HTRDYRRGIIPTEFGDVLIVIYP----MKNHMFSIQIMKKPEVPFFGPLFDGAI 1962
Query: 785 TFRKSDVFRDFLLAKVINAENAAHKSDKFHTMATRTRQEYLKDLAENCVSNTPID 839
K V + A INA A + R YL+ + ++ + T +
Sbjct: 1963 VNGK--VLPIMVRATAINASRALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFE 2015
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 63.9 bits (154), Expect = 1e-09
Identities = 152/693 (21%), Positives = 234/693 (33%), Gaps = 112/693 (16%)
Query: 1040 PFEDGTPRRGWPETYDMNTSEP-------KTEQESITPGGRPPYRSNAPWQWSGPASHNS 1092
P T R PET S P K E+ + P P S P P +
Sbjct: 313 PGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGP----EPPAPTP 368
Query: 1093 LPASKWATPTTPGHAQSLSRPLKQTPIVPFRESQPLHSKRPVSFPETPYTVSPAGADRVP 1152
L A + P + PL Q P+ P E+ P + P PE + ++ P
Sbjct: 369 LLAERHGGSPQP----LATTPLSQEPVNPPSEASPTRDRSPPKSPEK--LPQSSSSESSP 422
Query: 1153 PYRQPSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDP---HFSHDGTSSGDSSSGGLT 1209
P QP+ S S++ KP+P H +S P + SH G + D S
Sbjct: 423 PSPQPT-KVSRHASSSPESPKPAP---APGSHREISSSPTSKNRSH-GRAKRDKSHSHTP 477
Query: 1210 SQESTMERQKPEPLWHVPAQARLSAIAGSSGNKHPSRQDAAGKDSPN-RHSKGEPQYSSH 1268
S+ R PA A+ G S ++ P+++ + SP R S+ ++
Sbjct: 478 SRRMGRSRS--------PATAK----RGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRS 525
Query: 1269 SSSNTLSSNASSSHSDDRWFDPLDPLEPEQDPLSKGGSSDSGIDTTLYTSSPSCMSLAKA 1328
S + S P P + G S S ++ SP+ +++
Sbjct: 526 RSPQRRGRSRS----------PQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRS 575
Query: 1329 PRPAKPHKPPGSMGLCGGGREAAGRSHHADRRREVSPAPAVAGQSKGYRPKLYSSGSSTP 1388
PA+ + S R + RS RRR S PA G+S+ P S + +P
Sbjct: 576 RTPARRGR---SRSRTPARRRS--RSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSP 630
Query: 1389 TGLAGGSRDPPRQPSDMGSRVGYPAQVYKTASAETPRPSQLAQPSPFQLSASVPKSFFSK 1448
SR P R+ SR PA+ ++ S R + +P + S
Sbjct: 631 VRRRSRSRSPARRSGRSRSRT--PARRGRSRSRTPARRGRSRSRTPARRSGRS------- 681
Query: 1449 QPVRNKHPTGWKRTEEPPPRPLPFSDPKKQVDTNTKNVFGQPRLRASLRDLRS----PRK 1504
R++ P R+ PR G+ R R+ +R RS P++
Sbjct: 682 ---RSRTPARRGRSRSRTPRR------------------GRSRSRSLVRRGRSHSRTPQR 720
Query: 1505 NYKSTIEDDLKKLIIMDNLGPEQERDTGQSPQKGLQRTLSDESLCSGRREPSFASP---A 1561
+S + K + T Q + +S S RR S +SP A
Sbjct: 721 RGRSGSSSERKN-----------KSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKA 769
Query: 1562 GLEPGLPSDVLFTSTCAFPSSTLPARRQHQHPHPPVGPGATPA----AGSGFPEKKSTIS 1617
L + +S C S P RR P TP + S P K+ + +
Sbjct: 770 KSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKT 829
Query: 1618 ASELSLADGRDRPLRRLDPGLMPLPDTAAGLEWSSLVNAAKAYEVQRAVSLFSLNDPALS 1677
S S + P ++ G P + + + ++ QR S DP L
Sbjct: 830 PSRQSHSSSSPHP--KVKSGTPPRQGSITSPQANE-----QSVTPQRRSCFESSPDPELK 882
Query: 1678 PDIPPAHSPVHSHLSLERGPPTPRTTPTMSEEP 1710
P HS S + PR +P+ S P
Sbjct: 883 SRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSP 915
Score = 55.1 bits (131), Expect = 6e-07
Identities = 116/516 (22%), Positives = 192/516 (37%), Gaps = 70/516 (13%)
Query: 1061 PKT-EQESITPGGRPPYRSNAPWQWSGPASHNSLPASKWATPTTPGHAQSLSRP-LKQTP 1118
P+T +E + P + P S + S P + + T H+ S S P +K P
Sbjct: 1411 PRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIP 1470
Query: 1119 IVPFR-ESQPLHSKRPVSFPETPY--TVSPAGADR----VPPYRQPSGSFSTPGSATYVR 1171
P R S+ S P + P+TP + SP+ + + P R+ SGS S+ T R
Sbjct: 1471 RTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVAR 1530
Query: 1172 YKPSPERYTAAPHPLLSLDPHFSHDGTSSGDSSSGGLTSQESTM-ERQKPEPLWHVPAQA 1230
P +R + L + P S S DSS + + +R + V +++
Sbjct: 1531 -TPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKS 1589
Query: 1231 RLSAIAGSSGNKHPSRQDAAGKDSPNRHSKGEPQYSSHSSSNTLSSNASSSHSDDRWFDP 1290
RLS SG+ KD P + P+ S S S+ +P
Sbjct: 1590 RLSPRRSRSGSSPEV------KDKP----RAAPRAQSGSDSSP---------------EP 1624
Query: 1291 LDPLEPEQDPLSKGGSSDSGIDTTLYTSSPSCMSLAKAPRPAKPHKPPGSMGLCGGGR-- 1348
P S+ GSS G + SS + + P PP S G R
Sbjct: 1625 KAPAPRALPRRSRSGSSSKGRGPSPEGSSST---------ESSPEHPPKSRTARRGSRSS 1675
Query: 1349 -EAAGRSHHADRRREVSPAPAVAGQSKGYRPKLYSSGSSTPTGLAGGSRDPPRQPSDMGS 1407
E +S RRR +P + +++ R S SS+P SR PPR
Sbjct: 1676 PEPKTKSRTPPRRRSSRSSPELTRKARLSRRS--RSASSSPETR---SRTPPRHR----- 1725
Query: 1408 RVGYPAQVYKTASAETPRPSQLAQPSPFQLSASVPKSFFSKQPVR--NKHPTGWKRTEEP 1465
++ S +P P++ ++ S + SAS P++ + + R + P G +R+
Sbjct: 1726 ---------RSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSR 1776
Query: 1466 PPRPLPFSDPKKQVDTNTKNVFGQPRLRASLRDLRSPRKNYKSTIEDDLKKLIIMDNLGP 1525
R + ++ ++++ + R R+ R + R+ S
Sbjct: 1777 SRREKTRTTRRRDRSGSSQST-SRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSS 1835
Query: 1526 EQERDTGQSPQKGLQRTLSDESLCSGRREPSFASPA 1561
+ R ++P +R+ S S +R S ASPA
Sbjct: 1836 RRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPA 1871
Score = 52.8 bits (125), Expect = 3e-06
Identities = 89/387 (22%), Positives = 131/387 (33%), Gaps = 51/387 (13%)
Query: 1058 TSEPKTEQ-ESITPGGRPPY------RSNAPWQWSGPASHNSL--PASKWATPTTPGHAQ 1108
TS P ++ S TP P R+ +P G A SL PA P
Sbjct: 2397 TSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFS 2456
Query: 1109 SLSRPLKQTPIVPFRESQPLHSKRPVSFPETPYTVSPAGADR----VPPYRQPSGSFSTP 1164
SR L ++ P+ + +S T S AG VP P P
Sbjct: 2457 DQSRCL-------IAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEP 2509
Query: 1165 GSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTSSGDSSSGGLTSQESTMERQKPEPLW 1224
++T + + A S S +SS SSS +S S+ + L
Sbjct: 2510 PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP 2569
Query: 1225 HVPAQARLSAIAGSSGNKHPSRQDAAGKDSPNRHSKGEPQYSSHSSSNTLSSNASSSHSD 1284
P A + + K R+ + +P + + SS SSS++ SS++SSS S
Sbjct: 2570 VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSS- 2628
Query: 1285 DRWFDPLDPLEPEQDPLSKGGSSDSGIDTTLYTSSPSCMSLAKAPRPAKPHKPP------ 1338
S SS S ++ + SP+ P+PA P KPP
Sbjct: 2629 -------------SSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRS 2675
Query: 1339 -GSMGLCGGGREAAGRSHHADRRREVSPAPAVAGQSKGYRPKLYSSGSSTPTGLAGGSRD 1397
R++ S+ RR SP P+ Q SS+ G G R
Sbjct: 2676 RSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ----------QSSSSERGSRRGQRG 2725
Query: 1398 PPRQPSDMGSRVGYPAQVYKTASAETP 1424
R PS R + + S+ +P
Sbjct: 2726 DSRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 46.2 bits (108), Expect = 3e-04
Identities = 101/433 (23%), Positives = 150/433 (34%), Gaps = 116/433 (26%)
Query: 1039 PPFEDGTPRRGWPETYDMNTSEPKTEQESITPGGRPPYRSNAPWQWSGPASHNSLPASKW 1098
P + GTP R + + P+ ++S+TP R + S+ P K
Sbjct: 842 PKVKSGTPPR------QGSITSPQANEQSVTPQRRSCFESSPD------------PELKS 883
Query: 1099 ATPTTPGHAQSLSRPLKQTPIVPFRESQPLHSKRPVSFPETPYTVSPAGADRVPPYRQPS 1158
TP+ H+ S S P + P R+S P S P P+ +SP RQ S
Sbjct: 884 RTPSR--HSCSGSSPPRVKSSTPPRQS-PSRSSSPQ--PKVKAIISP---------RQRS 929
Query: 1159 GSFSTPGSATYVRYKPSPERYTAAPHPLLSLD----PHFSHDGTSSGD-----------S 1203
S S+ S + V + +P R + + P +++ P +SH G+SS D S
Sbjct: 930 HSGSSSPSPSRVTSRTTPRR-SRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQS 988
Query: 1204 SSGG----------------LTSQESTMERQKPEPLWHVPAQARLSAIAGSSGNKHPSRQ 1247
SG L+ +S ++K + LS AG + P +
Sbjct: 989 HSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPG-E 1047
Query: 1248 DAAGKDSPNRHSKGEPQYSSHSSSNTLSSNASSSHSDDRWFDPLDPLEPEQDPLSKGGSS 1307
G S KG+ Q S S+T S SHS+ L+ + KGG S
Sbjct: 1048 SYFGVSS--LQLKGQSQTSPDHRSDTSSPEVRQSHSES------PSLQSKSQTSPKGGRS 1099
Query: 1308 DSGIDTTLYTSSPSCMSLAKAPRPAKPHKPPGSMGLCGGGREAAGRSHHADRRREVSPAP 1367
S T E A RS R E S +P
Sbjct: 1100 RSSSPVT----------------------------------ELASRSPIRQDRGEFSASP 1125
Query: 1368 AVAGQSKGYRPKLYSSGSSTPT----GLAGGSRDPPRQPSDMGSRVGYPAQVYKTASAET 1423
+ + + S SS PT L G SR + ++ ++ P Q + A+A
Sbjct: 1126 MLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSR---LETAESKEKMALPPQ--EDATASP 1180
Query: 1424 PRPSQLAQPSPFQ 1436
PR P P Q
Sbjct: 1181 PRQKDKFSPFPVQ 1193
Score = 44.7 bits (104), Expect = 8e-04
Identities = 96/420 (22%), Positives = 153/420 (36%), Gaps = 39/420 (9%)
Query: 1088 ASHNSLPASKWATP-TTPGHAQSLSRPLKQTPIVPFRESQPLHSKRPVSFPETPYTVSPA 1146
AS +S S+ ATP T H+ S + P+ S+P S P+ +P + P
Sbjct: 2080 ASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPL 2139
Query: 1147 GADRVP--PYRQPSGS-FSTPGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTSSGDS 1203
G+ R P +Q GS PG + S A L+L
Sbjct: 2140 GSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSM 2199
Query: 1204 SSGGLTSQESTMERQKPEPLWHVPAQARLSAIAGSSGNKHPSRQDAAGKDSPNRHSKGEP 1263
S+ GL ++ S Q P P VP + +A A + ++ P+ AA + + + P
Sbjct: 2200 SAAGLAARMS----QVPAP---VPLMSLRTAPAANLASRIPA-ASAAAMNLASARTPAIP 2251
Query: 1264 QYSSHSSSNTLSSNASSSHSDDR---------WFDPLDPLEPEQDPLSKGGSSDSGIDTT 1314
+ + S T ++ A+ + + R DP P P + G + + +
Sbjct: 2252 TAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVN--LAGARTPAALAAL 2309
Query: 1315 LYTSSPSCMSLAKAPRPAKPHKPPGSMGLCGGGREAAGRSHHADRRREVSPAPAVAGQSK 1374
T S + + A P ++ + P S L G RS HA ++ + A +
Sbjct: 2310 SLTGSGTPPTAANYPSSSRTPQAPASANLVG------PRSAHATAPVNIAGSRTAAALA- 2362
Query: 1375 GYRPKLYSSGSSTPTGLAGGSRDPPRQPSDMGSRVG--YPAQVYKTASAETPRPSQLAQP 1432
P +S P L+G + PR P RV + A + TP PS +Q
Sbjct: 2363 ---PASLTSARMAP-ALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTP-PSAPSQS 2417
Query: 1433 SPFQLSASVPKSFFSKQPVRNKHPTGWKRTEEPPPRPLPFSDPKKQVDTNTKNVFGQPRL 1492
A P S + P ++ P + P P FSD + + T V G L
Sbjct: 2418 RMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPS--AFSDQSRCLIAQTTPVAGSQSL 2475
Score = 42.7 bits (99), Expect = 0.003
Identities = 100/449 (22%), Positives = 160/449 (35%), Gaps = 59/449 (13%)
Query: 1067 SITPGGRPPYRSNAPWQW---SGPASHNSL-PASKWATP------------------TTP 1104
S+T G PP +N P PAS N + P S AT T+
Sbjct: 2310 SLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSA 2369
Query: 1105 GHAQSLSRPLKQTPIVPFRESQPLHSKRPVSFPETPYTVSPAGA---DRVPPYRQPSGSF 1161
A +LS +P VP + + + + + +P A R+ R PS S
Sbjct: 2370 RMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPS- 2428
Query: 1162 STPGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTSSGDSSSGGLTS---QESTMERQ 1218
S G A P + +P P D ++ + S L+S +T
Sbjct: 2429 SRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAG 2488
Query: 1219 KPEPLWHVPAQARLSAIAG----SSGNKHPSRQDAAGKDSPNRHSKGEPQYSSHSSSNTL 1274
+ VPA + G S+G + PS AA + + R S SS SSS++
Sbjct: 2489 DHNGMLSVPAPGVPHSDVGEPPASTGAQQPSAL-AALQPAKERRSSSSSSSSSSSSSSSS 2547
Query: 1275 SSNASSSHSDDRWFDPLDPLEPEQDPLSKGGSSDSGIDTTLYTSSPSCMSLAKAPRPAKP 1334
SS++SSS S D S+G S + L + +A R +P
Sbjct: 2548 SSSSSSSSSGSSSSD------------SEGSSLPVQPEVALKRVPSPTPAPKEAVREGRP 2595
Query: 1335 HKPPGSMGLCGGGREAAGRSHHADRRREVSPAPAVAGQSKGYRPKLYSSGSSTPTGLAGG 1394
+P + ++ S + S + + + S SS SS+P+ G
Sbjct: 2596 PEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG 2655
Query: 1395 SRDPPRQPSDMGSRVGY--------PAQVYKTASAETPRPSQLAQPSPF-----QLSASV 1441
+ P+ S G P + + + + P + +PSP Q S+S
Sbjct: 2656 PQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSS 2715
Query: 1442 PKSFFSKQPVRNKHPTGWKRTEEPPPRPL 1470
+ Q ++ P+ +R E P PRP+
Sbjct: 2716 ERGSRRGQRGDSRSPSHKRRRETPSPRPM 2744
Score = 36.2 bits (82), Expect = 0.29
Identities = 25/125 (20%), Positives = 54/125 (43%), Gaps = 2/125 (1%)
Query: 41 AQNGSMSQPLGESPATATATATATTRPSPTTPAMPKMGVRARVADWPPKREALREHSNPS 100
+ + S S S +++++ ++++ + P P++ ++ + P +EA+RE P
Sbjct: 2538 SSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPE 2597
Query: 101 PSQDTDGTKATKMAHSMRSIQNGQPPTSTPASSGSKAFHRLSRRRSKDVEFQDGWPRSPG 160
P+ +++ + S S + +S+ +SS S + S S P PG
Sbjct: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS--PAKPG 2655
Query: 161 RAFLP 165
LP
Sbjct: 2656 PQALP 2660
Score = 35.4 bits (80), Expect = 0.50
Identities = 35/139 (25%), Positives = 63/139 (45%), Gaps = 20/139 (14%)
Query: 41 AQNGSMSQPLGESPATATATATATTRPSPTTPAMPKMGVRARVADWPPKREALREHSNPS 100
+ + S S S +++++++++++ PSP P G +A PK+ E + S
Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP-----GPQALPKPASPKKPPPGERRSRS 2677
Query: 101 PSQDTDGTKATKMAHSMRSIQNGQP-PTSTPASSGSKAFHRLSRRRSKDVEFQDGWPRSP 159
P + D + ++ + S ++ +P P +P S + R SRR Q G RSP
Sbjct: 2678 PRKPIDSLRDSR-SLSYSPVERRRPSPQPSPRDQQSSSSERGSRRG------QRGDSRSP 2730
Query: 160 GR-------AFLPLRHRSS 171
+ P+RHRSS
Sbjct: 2731 SHKRRRETPSPRPMRHRSS 2749
>gi|116256350 tuberous sclerosis 2 isoform 4 [Homo sapiens]
Length = 1740
Score = 63.2 bits (152), Expect = 2e-09
Identities = 44/136 (32%), Positives = 69/136 (50%), Gaps = 12/136 (8%)
Query: 623 HKVGILYCKAGQSSEE-EMYNNEEAGPAFEEFLSLIGEKVCLKGFTK---YAAQLDVKTD 678
HK+ +LY GQS+ E + +NE + EFL+ +G + LK Y LDV
Sbjct: 1476 HKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDV--- 1532
Query: 679 STGTHSLYTMYQDYEIM---FHVSTLLPYTPNNRQQLLRKRHIGNDIVTIIFQEPGALPF 735
G +T +IM FH++TL+P ++ + +KRH+GND V+I++ + G F
Sbjct: 1533 -CGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGE-DF 1590
Query: 736 TPKNIRSHFQHVFIIV 751
I+ F V +IV
Sbjct: 1591 KLGTIKGQFNFVHVIV 1606
>gi|116256352 tuberous sclerosis 2 isoform 1 [Homo sapiens]
Length = 1807
Score = 63.2 bits (152), Expect = 2e-09
Identities = 44/136 (32%), Positives = 69/136 (50%), Gaps = 12/136 (8%)
Query: 623 HKVGILYCKAGQSSEE-EMYNNEEAGPAFEEFLSLIGEKVCLKGFTK---YAAQLDVKTD 678
HK+ +LY GQS+ E + +NE + EFL+ +G + LK Y LDV
Sbjct: 1543 HKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDV--- 1599
Query: 679 STGTHSLYTMYQDYEIM---FHVSTLLPYTPNNRQQLLRKRHIGNDIVTIIFQEPGALPF 735
G +T +IM FH++TL+P ++ + +KRH+GND V+I++ + G F
Sbjct: 1600 -CGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGE-DF 1657
Query: 736 TPKNIRSHFQHVFIIV 751
I+ F V +IV
Sbjct: 1658 KLGTIKGQFNFVHVIV 1673
>gi|167412124 tuberous sclerosis 2 isoform 5 [Homo sapiens]
Length = 1784
Score = 63.2 bits (152), Expect = 2e-09
Identities = 44/136 (32%), Positives = 69/136 (50%), Gaps = 12/136 (8%)
Query: 623 HKVGILYCKAGQSSEE-EMYNNEEAGPAFEEFLSLIGEKVCLKGFTK---YAAQLDVKTD 678
HK+ +LY GQS+ E + +NE + EFL+ +G + LK Y LDV
Sbjct: 1520 HKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDV--- 1576
Query: 679 STGTHSLYTMYQDYEIM---FHVSTLLPYTPNNRQQLLRKRHIGNDIVTIIFQEPGALPF 735
G +T +IM FH++TL+P ++ + +KRH+GND V+I++ + G F
Sbjct: 1577 -CGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGE-DF 1634
Query: 736 TPKNIRSHFQHVFIIV 751
I+ F V +IV
Sbjct: 1635 KLGTIKGQFNFVHVIV 1650
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 60.1 bits (144), Expect = 2e-08
Identities = 132/626 (21%), Positives = 209/626 (33%), Gaps = 115/626 (18%)
Query: 1038 IPPFEDGTPRRGWPETYDMNTSEPKTEQESITPGGRPPYRSNAPWQWSGPASHNSLPAS- 1096
IP ++ +P + + + + P++ S + R RS +P H S S
Sbjct: 253 IPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKS---RSRTRSRSPSHTRPRRRHRSRSRSY 309
Query: 1097 ---KWATPTTPGHAQSLSRPLKQTPIVPFRESQ-PLHSKRPVSFPETPYTVSPAGA-DRV 1151
+ +P + + P + P R S+ P+ +R S + + S + + R
Sbjct: 310 SPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRS 369
Query: 1152 PPYRQPSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTS------------ 1199
PP + P + S P + SP R P P + P H T
Sbjct: 370 PPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVS 429
Query: 1200 -SGDSSSGGLTSQESTMERQKPEPLWHVPAQARLSAIAGSSGNKHPSRQDAAGKDSPNRH 1258
S +SG +T + T +R+ P P P + LS S +D GK +
Sbjct: 430 VSPGRTSGKVTKHKGTEKRESPSPA-PKPRKVELSE----------SEEDKGGKMAAADS 478
Query: 1259 SKGEPQYSSHSSSNTLSSNASSSHSDDRWFDPLDPLEPEQDPLSKGGSSDSGIDTTLYTS 1318
+ QY + ++ S +SSS D+R P++ + G + ++
Sbjct: 479 VQQRRQYRRQNQQSSSDSGSSSSSEDER---------PKRSHVKNGEVGRRRRHSPSRSA 529
Query: 1319 SPSCMSLAKAPRPAKPHKPPGSMGLCGGGREAAGRSHHADRRREVSPAPAVAGQSKGYRP 1378
SPS P K K G RRR SP P +S P
Sbjct: 530 SPS---------PRKRQKETSPRGR---------------RRRSPSPPPTRRRRSPSPAP 565
Query: 1379 KLYSSGSSTPTGLAGGSRDPPRQPSDMGSRVGYPAQ--------VYKTASAETPRPSQLA 1430
+ TP PPR+ S R P Q + ++ P P + A
Sbjct: 566 PPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRA 625
Query: 1431 QPSP---FQLSASVPKSFFSKQPVRNKHP---------------TGWKRTEEPPPRPLPF 1472
PSP ++S S P S + + P T R+ +P R P
Sbjct: 626 SPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPS 685
Query: 1473 SDPKKQVDTNT-----KNVFGQPRLRASLRDLRSPRKNYKSTIEDDLKKLIIMDNLGPEQ 1527
P+ +++ + P+ R S P + T E KK+
Sbjct: 686 PRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP--KKI---------- 733
Query: 1528 ERDTGQSPQKGLQRTLSDESLCSGRREPSFASPAGLEPGLPSDVLFTSTCAFPSSTLPAR 1587
++ SPQ R +S SG EP+ P P PS V S S +P +
Sbjct: 734 KKAASPSPQS--VRRVSSSRSVSGSPEPAAKKP----PAPPSPVQSQSPSTNWSPAVPVK 787
Query: 1588 RQHQHPHPPVGPGATPAAGSGFPEKK 1613
+ P P + G G +KK
Sbjct: 788 KAKSPTPSPSPPRNSDQEGGGKKKKK 813
>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
Length = 1142
Score = 53.9 bits (128), Expect = 1e-06
Identities = 83/372 (22%), Positives = 130/372 (34%), Gaps = 42/372 (11%)
Query: 1088 ASHNSLPASKWATPTTPGHAQSLSRPLKQTPIVPFRESQPLHSKRPVSFPETPYTVSPAG 1147
++ P S P +P ++ PL+ P +P E S P FP++P P G
Sbjct: 504 STFEGFPQSPLQIPQSPPEGENTHSPLQIVPSLPEWED----SLSPHYFPQSP----PQG 555
Query: 1148 ADRVPPYRQPSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTSSGDSSSGG 1207
D + P+ P S SP + +P SL PH+ G+ S
Sbjct: 556 EDSLSPHYFPQSPPQGEDSL-------SPHYFPQSPQGEDSLSPHYFPQSPPQGEDSMSP 608
Query: 1208 LTSQESTMERQKPEPLWHVPAQARLSAIAGSSGNKHP--SRQDAAGKDSPNRHSKGEPQY 1265
L +S ++ ++ + P S+ S P S+ G HS P
Sbjct: 609 LYFPQSPLQGEEFQSSLQSPVSICSSSTPSSLPQSFPESSQSPPEGPVQSPLHSPQSPPE 668
Query: 1266 SSHSSSNTLSSNASSSHSDDRWFDPLDPLEPEQDPLSKGGSSDSGIDTTLYTSSPSCMSL 1325
HS S L S S+ + D L PL+ Q PL + + + + SP
Sbjct: 669 GMHSQS-PLQSPESAPEGE----DSLSPLQIPQSPL----EGEDSLSSLHFPQSPPEWED 719
Query: 1326 AKAPRPAKPHKPPGS---------MGLCGGGREAAGRSHHADRRREVSPAPAVAGQSKGY 1376
+ +P P G + +C + + + PA QS
Sbjct: 720 SLSPLHFPQFPPQGEDFQSSLQSPVSICSSSTSLSLPQSFPESPQSPPEGPA---QSPLQ 776
Query: 1377 RPKLYSSGSSTPTGLAGGSRDPPRQPSDMGSRVGYPAQVYKTASAETPRPSQLAQPSPFQ 1436
RP + S S T L S + P+ P + ++ + V +S + S L+Q SP
Sbjct: 777 RP-VSSFFSYTLASLLQSSHESPQSPPEGPAQSPLQSPV---SSFPSSTSSSLSQSSPVS 832
Query: 1437 LSASVPKSFFSK 1448
S S SK
Sbjct: 833 SFPSSTSSSLSK 844
>gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sapiens]
Length = 1747
Score = 53.1 bits (126), Expect = 2e-06
Identities = 166/733 (22%), Positives = 254/733 (34%), Gaps = 107/733 (14%)
Query: 990 VEDYGFAWQAGLRQGSRLVEICKVAVVTLTHDQMIDLLR---TSVTVKVVII--PPFEDG 1044
V+ G AW+AGLR G L+E+ V VV + H Q++ L+R + +KVV + P EDG
Sbjct: 629 VDVEGVAWRAGLRTGDFLIEVNGVNVVKVGHKQVVALIRQGGNRLVMKVVSVTRKPEEDG 688
Query: 1045 TPRRGWP----------------------ETYDMNTSEPKTEQESITPGGRPPYRSNAPW 1082
RR P E + + + E + P R +
Sbjct: 689 ARRRAPPPPKRAPSTTLTLRSKSMTAELEELASIRRRKGEKLDEMLAAAAEPTLRPDIAD 748
Query: 1083 QWSGPASHNSLPASKWATPT----------TPGHAQ---SLSRPLKQTPIVPFRESQPLH 1129
S A+ P S+ TP PG + SL + + +T V E + L
Sbjct: 749 ADSRAATVKQRPTSRRITPAEISSLFERQGLPGPEKLPGSLRKGIPRTKSV--GEDEKLA 806
Query: 1130 SKRPVSFPETPYTVSPAGADR-VPPYRQPSGSFSTPGSATYVRYKPSPERYTAAPHPLLS 1188
S FP + P R +PP P + P A Y P ++ P P +
Sbjct: 807 SLLEGRFPRSTSMQDPVREGRGIPP---PPQTAPPPPPAPYYFDSGPPPAFSPPPPPGRA 863
Query: 1189 LD---PHFSHDGTSSGDSSSGGLTSQESTM-ERQKPEPLWHVPAQARLSAIAGSSGNKHP 1244
D F + + + GL + + PE + L A SG+
Sbjct: 864 YDTVRSSFKPGLEARLGAGAAGLYEPGAALGPLPYPERQKRARSMIILQDSAPESGDAPR 923
Query: 1245 SRQDAAGKDSPNRHSKGEPQYSSHSSSNTLSSNASSSHSDDRWFDPLDPLEPEQDPLSKG 1304
A + P R + S +++ S++ + R PL +D +
Sbjct: 924 PPPAATPPERPKRRPRPPGPDSPYANLGAFSASLFAPSKPQRRKSPLVKQLQVEDAQERA 983
Query: 1305 GSSDSGIDTTLYTSSPSCMSLAKAPRPAKPHKPPGSM--------GLCGGGREAAGRSHH 1356
+ + P S A+ P P PG + GL GG A
Sbjct: 984 A-------LAVGSPGPGGGSFAREPSPTHRGPRPGGLDYGAGDGPGLAFGGPGPAKDRRL 1036
Query: 1357 ADRRREV--SPAPAVAGQSKGY-RPKLYSSGSSTPTGLAGG---SRD--PPRQPSDMGSR 1408
+RRR A+ G + G P L S S L G RD P S +
Sbjct: 1037 EERRRSTVFLSVGAIEGSAPGADLPSLQPSRSIDERLLGTGPTAGRDLLLPSPVSALKPL 1096
Query: 1409 VGYPAQVYKTASAETPRPSQLAQP-SPFQLS-ASVPKSFFSKQPVRNKHPTGWKRTEEPP 1466
V P+ ++ P + P SP L+ A+ ++ S+ P R+ P + P
Sbjct: 1097 VSGPSLGPSGSTFIHPLTGKPLDPSSPLALALAARERALASQAPSRSPTPVHSPDADRPG 1156
Query: 1467 PRPLPFSDPKKQVDTNTKNVFGQPRLRA-----SLRDLRSPRKNYKSTIEDDLKKLIIMD 1521
P + + + F PR A + R+ + + + ED KK +I+
Sbjct: 1157 PLFVDVQARDPERGSLASPAF-SPRSPAWIPVPARREAEKVPREERKSPED--KKSMILS 1213
Query: 1522 NLGPEQERDTGQSPQKGLQRTLSDESLCSGRREPSFASPAGLE-PGLPSDVLFTSTCAFP 1580
L +R G L S +EPS A E PG P A
Sbjct: 1214 VLDTSLQRPAG----------LIVVHATSNGQEPSRLGGAEEERPGTPELAPAPMQSAAV 1263
Query: 1581 SSTLPARRQHQHPHPPVGPGATPAAGSGFPEKKS------TISASELSLADGRDR-PLRR 1633
+ LP+ R PP G A G G E++ + ++LS +D R L R
Sbjct: 1264 AEPLPSPR----AQPPGGTPADAGPGQGSSEEEPELVFAVNLPPAQLSSSDEETREELAR 1319
Query: 1634 LDPGLMPLPDTAA 1646
+ GL+P P+ A
Sbjct: 1320 I--GLVPPPEEFA 1330
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 52.8 bits (125), Expect = 3e-06
Identities = 147/633 (23%), Positives = 203/633 (32%), Gaps = 122/633 (19%)
Query: 1051 PETYDMNTSEPKTEQESITPGGRPPYRSNAPWQWSGPASHNSLPASKWATPTTPGHAQSL 1110
P Y P + PG PP+ P G S + P G A S+
Sbjct: 191 PTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMG------PKGGGAASSV 244
Query: 1111 SRPL--KQTPIVPFRESQPLHSKRPVSFPETPYTVSPAGADRVPPYRQPSGSFSTPGSAT 1168
P KQ P P TP +VS +GA PP + P +TP
Sbjct: 245 GGPNGGKQHPP-----------------PTTPISVSSSGASGAPPTKPP----TTPVGGG 283
Query: 1169 YVRYKPSPERYTAAPHPLLSLDPHFSHDGTSSGDSSSGGLTSQESTMERQKPEPLWHVPA 1228
+ P P + PH +L P + ++ +S GL +Q P P H+P+
Sbjct: 284 NLPSAPPPANF---PHVTPNLPPPPALRPLNNASASPPGLGAQ--------PLP-GHLPS 331
Query: 1229 QARLSAIAGS---SGNKHPSRQDAAGKDSPNRHSKGEP----QYSSHSSSNTLSSNASSS 1281
+ G K P+ + P S P YSS SSS+ +S++SSS
Sbjct: 332 PHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSS 391
Query: 1282 HSDDRWFDPLD---PLEPEQDPLSKGGSSDSGIDTTLYTSSPSCMSLAKAPRPAKPH--- 1335
S P P P P S + S PS ++ P P P+
Sbjct: 392 SSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRL 451
Query: 1336 -----KPPGSMGLCGGGREAAG---RSHHADRRREVSPAPAVAGQSKGYRPKLYSSG--- 1384
PG G + A +HH +++ Q + + +SG
Sbjct: 452 LANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP 511
Query: 1385 -SSTPTGLAGGS---RDPPRQPSDMGSRVGYPAQVYKTASAETPRP------SQLAQPSP 1434
+ P L GGS P +GS YP A P P SQ P
Sbjct: 512 PGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYP-----PGPAHLPPPHSQVSYSQAGPNGP 566
Query: 1435 FQLSASVPKSFFSKQPVRNKHPTGWKRTEEPPPRPLPFSDPKKQVDTNTKNVFGQPRLRA 1494
S+S S S+ HP+ ++ P P PF P V T++ L
Sbjct: 567 PVSSSSNSSSSTSQGSYPCSHPS---PSQGPQGAPYPF-PPVPTVTTSSAT------LST 616
Query: 1495 SLRDLRSPRKNYKSTIEDDLKKLIIMDNLGPEQERDTGQSPQKGLQRTLSDESLCSGRRE 1554
+ + S YK+ GP SP G +T + G
Sbjct: 617 VIATVASSPAGYKTASPP-----------GPPPYGKRAPSP--GAYKTATPPGYKPG--- 660
Query: 1555 PSFASPAGLEPGLPSDVLFTSTCAFPSSTLPARRQHQHPHPPVGPGATPAAG-SGFPE-- 1611
SP G P TS A P + P P VGPG P AG SG P
Sbjct: 661 ----SPPSFRTGTPPGYRGTSPPAGPGTFKPG-------SPTVGPGPLPPAGPSGLPSLP 709
Query: 1612 --KKSTISASELSLADGRDRPLRRLDPGLMPLP 1642
+ S LS + P + P+P
Sbjct: 710 PPPAAPASGPPLSATQIKQEPAEEYETPESPVP 742
Score = 31.2 bits (69), Expect = 9.4
Identities = 35/150 (23%), Positives = 50/150 (33%), Gaps = 14/150 (9%)
Query: 1039 PPFEDGTPRRGWPETYDMNTSEPKTEQESITPGGRPPYRSNAP----WQWSGPASHNSLP 1094
PP T T + ++ +P G PPY AP ++ + P +
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661
Query: 1095 ASKWATPTTPGH--AQSLSRPLKQTPIVPFRESQPLHSKRPVSFPETPYTVSPAGADRVP 1152
+ T T PG+ + P P P PL P P P PA P
Sbjct: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLP--PPPAAPASGP 719
Query: 1153 PY------RQPSGSFSTPGSATYVRYKPSP 1176
P ++P+ + TP S PSP
Sbjct: 720 PLSATQIKQEPAEEYETPESPVPPARSPSP 749
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 52.8 bits (125), Expect = 3e-06
Identities = 147/633 (23%), Positives = 203/633 (32%), Gaps = 122/633 (19%)
Query: 1051 PETYDMNTSEPKTEQESITPGGRPPYRSNAPWQWSGPASHNSLPASKWATPTTPGHAQSL 1110
P Y P + PG PP+ P G S + P G A S+
Sbjct: 191 PTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMG------PKGGGAASSV 244
Query: 1111 SRPL--KQTPIVPFRESQPLHSKRPVSFPETPYTVSPAGADRVPPYRQPSGSFSTPGSAT 1168
P KQ P P TP +VS +GA PP + P +TP
Sbjct: 245 GGPNGGKQHPP-----------------PTTPISVSSSGASGAPPTKPP----TTPVGGG 283
Query: 1169 YVRYKPSPERYTAAPHPLLSLDPHFSHDGTSSGDSSSGGLTSQESTMERQKPEPLWHVPA 1228
+ P P + PH +L P + ++ +S GL +Q P P H+P+
Sbjct: 284 NLPSAPPPANF---PHVTPNLPPPPALRPLNNASASPPGLGAQ--------PLP-GHLPS 331
Query: 1229 QARLSAIAGS---SGNKHPSRQDAAGKDSPNRHSKGEP----QYSSHSSSNTLSSNASSS 1281
+ G K P+ + P S P YSS SSS+ +S++SSS
Sbjct: 332 PHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSS 391
Query: 1282 HSDDRWFDPLD---PLEPEQDPLSKGGSSDSGIDTTLYTSSPSCMSLAKAPRPAKPH--- 1335
S P P P P S + S PS ++ P P P+
Sbjct: 392 SSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRL 451
Query: 1336 -----KPPGSMGLCGGGREAAG---RSHHADRRREVSPAPAVAGQSKGYRPKLYSSG--- 1384
PG G + A +HH +++ Q + + +SG
Sbjct: 452 LANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP 511
Query: 1385 -SSTPTGLAGGS---RDPPRQPSDMGSRVGYPAQVYKTASAETPRP------SQLAQPSP 1434
+ P L GGS P +GS YP A P P SQ P
Sbjct: 512 PGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYP-----PGPAHLPPPHSQVSYSQAGPNGP 566
Query: 1435 FQLSASVPKSFFSKQPVRNKHPTGWKRTEEPPPRPLPFSDPKKQVDTNTKNVFGQPRLRA 1494
S+S S S+ HP+ ++ P P PF P V T++ L
Sbjct: 567 PVSSSSNSSSSTSQGSYPCSHPS---PSQGPQGAPYPF-PPVPTVTTSSAT------LST 616
Query: 1495 SLRDLRSPRKNYKSTIEDDLKKLIIMDNLGPEQERDTGQSPQKGLQRTLSDESLCSGRRE 1554
+ + S YK+ GP SP G +T + G
Sbjct: 617 VIATVASSPAGYKTASPP-----------GPPPYGKRAPSP--GAYKTATPPGYKPG--- 660
Query: 1555 PSFASPAGLEPGLPSDVLFTSTCAFPSSTLPARRQHQHPHPPVGPGATPAAG-SGFPE-- 1611
SP G P TS A P + P P VGPG P AG SG P
Sbjct: 661 ----SPPSFRTGTPPGYRGTSPPAGPGTFKPG-------SPTVGPGPLPPAGPSGLPSLP 709
Query: 1612 --KKSTISASELSLADGRDRPLRRLDPGLMPLP 1642
+ S LS + P + P+P
Sbjct: 710 PPPAAPASGPPLSATQIKQEPAEEYETPESPVP 742
Score = 31.2 bits (69), Expect = 9.4
Identities = 35/150 (23%), Positives = 50/150 (33%), Gaps = 14/150 (9%)
Query: 1039 PPFEDGTPRRGWPETYDMNTSEPKTEQESITPGGRPPYRSNAP----WQWSGPASHNSLP 1094
PP T T + ++ +P G PPY AP ++ + P +
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661
Query: 1095 ASKWATPTTPGH--AQSLSRPLKQTPIVPFRESQPLHSKRPVSFPETPYTVSPAGADRVP 1152
+ T T PG+ + P P P PL P P P PA P
Sbjct: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLP--PPPAAPASGP 719
Query: 1153 PY------RQPSGSFSTPGSATYVRYKPSP 1176
P ++P+ + TP S PSP
Sbjct: 720 PLSATQIKQEPAEEYETPESPVPPARSPSP 749
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 52.8 bits (125), Expect = 3e-06
Identities = 94/389 (24%), Positives = 131/389 (33%), Gaps = 60/389 (15%)
Query: 1074 PPYRSNAPWQWSGPASHNSLPASKWATPTTPGHAQSLSRPLKQTPIVPFRESQPLHSKRP 1133
PPY P SG P +P H Q P Q P +QP + ++P
Sbjct: 452 PPYGQQGP---SGYGQQGQTPYYNQQSP----HPQQQQPPYSQQPPSQTPHAQPSYQQQP 504
Query: 1134 VSFPETPYTVSPAGADRVPPY-RQPSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPH 1192
S P P PPY +QPS A Y PS ++ T HP P
Sbjct: 505 QSQP-------PQLQSSQPPYSQQPSQPPHQQSPAPY----PS-QQSTTQQHP--QSQPP 550
Query: 1193 FSHDGTSSGDSSSGGLTSQESTMERQKPEPLWHVPAQARLSAIAGSSGNKHPSRQDAAGK 1252
+S S ST+ +Q P Q++ S S + P Q+ +
Sbjct: 551 YSQPQAQSPYQQQQPQQPAPSTLSQQAAYP----QPQSQQSQQTAYSQQRFPPPQELSQD 606
Query: 1253 DSPNRHSKGEPQYSSHSSSNTLSSNASSSHSDDRWFDPLDPLEPEQDPLSKG--GSSDSG 1310
++ S SS ++ + S S L L D L G G+ G
Sbjct: 607 SFGSQASSAPSMTSSKGGQEDMNLSLQSRPSS------LPDLSGSIDDLPMGTEGALSPG 660
Query: 1311 IDTTLYTSSPSCMSLAKAPRPAKPHKPPGSMGLCGGGREAAGRSHHADRRREVSPAPAVA 1370
+ T+ +SS S A P PH P G+ G G +PA
Sbjct: 661 VSTSGISSSQGEQS-NPAQSPFSPHTSPHLPGIRGPSPSPVG-------------SPASV 706
Query: 1371 GQSKGYRPKLYSSGSSTPTGLAGGSRDPPRQPSDMGSRVGYPAQVYKTASAETPRPSQLA 1430
QS+ SG +P + G PPR PS + +P+ +S R
Sbjct: 707 AQSR--------SGPLSPAAVPGNQM-PPRPPSGQSDSIMHPSM--NQSSIAQDRGYMQR 755
Query: 1431 QPSPFQLSASVPKSFFS-KQPVRNKHPTG 1458
P Q S+ P S S +QP + TG
Sbjct: 756 NPQMPQYSSPQPGSALSPRQPSGGQIHTG 784
Score = 50.4 bits (119), Expect = 1e-05
Identities = 119/568 (20%), Positives = 180/568 (31%), Gaps = 100/568 (17%)
Query: 1059 SEPKTEQESITPGGRPPYRSNA---PWQWSGPASHNSLPASKWATPTTPGHAQSLSRPLK 1115
+EP + + G RP +N P G +S A P A +P
Sbjct: 96 AEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYG 155
Query: 1116 QTP-IVPFRESQPLHSKRPVSFPETPYTVSPAGADRVPPYRQPSGSFSTPGSATYVRYKP 1174
++P V + H + + G + PY P + G +
Sbjct: 156 RSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSY 215
Query: 1175 SPERYTAAPHPLLSLDPHFSHDGTSSGDSSSGGLTSQESTMERQKPEPLWHVPAQARLSA 1234
P R +A P P P ++ G SG + S KP P A + S+
Sbjct: 216 YPNR-SAYPPPA----PAYALSSPRGGTPGSGAAAAAGS-----KPPPSSSASASSSSSS 265
Query: 1235 IAGSSGNKHPSRQDAAGKDSPNRHSKGEPQYSSHSSSNTLSSNASSSHSDDRWFDPLDPL 1294
A R A G P+ G PQ ++ + N L ++ SS+ +
Sbjct: 266 FA-------QQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGY------- 311
Query: 1295 EPEQDPLSKGGSSDSGIDTTLYTSSPSCMSLAKAPRPA---------KPHKPPGSMGLCG 1345
P D GG D G + C A A A + H P S G G
Sbjct: 312 -PGGD--YSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSG 368
Query: 1346 GGREAAGR----SHHADRRREVSPAPAVAGQSKGYRPKLYSSGSSTPTGLAG---GSRDP 1398
GG + R S D+ ++ P P G + + + SG G G GS+ P
Sbjct: 369 GGGQPLARTPQPSSPMDQMGKMRPQP-YGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP 427
Query: 1399 PRQPSDMGSRV----------------------GY---------------PAQVYKTASA 1421
R P M R GY P Q S
Sbjct: 428 QRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQ 487
Query: 1422 ETPRPSQLAQPSPFQLSASVPKSFFSKQPVRNKHPTGWKRTEEPPPRPLPFSDPKKQVDT 1481
+ P + AQPS Q S P S QP ++ P+ + + P P P Q
Sbjct: 488 QPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPS--QPPHQQSPAPYPSQQSTTQQHP 545
Query: 1482 NTKNVFGQPRLRASLRDLRSPRKNYKSTIEDDLKKLIIMDNLGPEQERDTGQSPQKGLQR 1541
++ + QP+ ++ + + P++ ST+ P+ + Q QR
Sbjct: 546 QSQPPYSQPQAQSPYQQ-QQPQQPAPSTLSQQAAY--------PQPQSQQSQQTAYSQQR 596
Query: 1542 TLSDESLCSGRREPSFASPAGLEPGLPS 1569
+ L + SF S A P + S
Sbjct: 597 FPPPQEL----SQDSFGSQASSAPSMTS 620
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 52.8 bits (125), Expect = 3e-06
Identities = 94/389 (24%), Positives = 131/389 (33%), Gaps = 60/389 (15%)
Query: 1074 PPYRSNAPWQWSGPASHNSLPASKWATPTTPGHAQSLSRPLKQTPIVPFRESQPLHSKRP 1133
PPY P SG P +P H Q P Q P +QP + ++P
Sbjct: 452 PPYGQQGP---SGYGQQGQTPYYNQQSP----HPQQQQPPYSQQPPSQTPHAQPSYQQQP 504
Query: 1134 VSFPETPYTVSPAGADRVPPY-RQPSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPH 1192
S P P PPY +QPS A Y PS ++ T HP P
Sbjct: 505 QSQP-------PQLQSSQPPYSQQPSQPPHQQSPAPY----PS-QQSTTQQHP--QSQPP 550
Query: 1193 FSHDGTSSGDSSSGGLTSQESTMERQKPEPLWHVPAQARLSAIAGSSGNKHPSRQDAAGK 1252
+S S ST+ +Q P Q++ S S + P Q+ +
Sbjct: 551 YSQPQAQSPYQQQQPQQPAPSTLSQQAAYP----QPQSQQSQQTAYSQQRFPPPQELSQD 606
Query: 1253 DSPNRHSKGEPQYSSHSSSNTLSSNASSSHSDDRWFDPLDPLEPEQDPLSKG--GSSDSG 1310
++ S SS ++ + S S L L D L G G+ G
Sbjct: 607 SFGSQASSAPSMTSSKGGQEDMNLSLQSRPSS------LPDLSGSIDDLPMGTEGALSPG 660
Query: 1311 IDTTLYTSSPSCMSLAKAPRPAKPHKPPGSMGLCGGGREAAGRSHHADRRREVSPAPAVA 1370
+ T+ +SS S A P PH P G+ G G +PA
Sbjct: 661 VSTSGISSSQGEQS-NPAQSPFSPHTSPHLPGIRGPSPSPVG-------------SPASV 706
Query: 1371 GQSKGYRPKLYSSGSSTPTGLAGGSRDPPRQPSDMGSRVGYPAQVYKTASAETPRPSQLA 1430
QS+ SG +P + G PPR PS + +P+ +S R
Sbjct: 707 AQSR--------SGPLSPAAVPGNQM-PPRPPSGQSDSIMHPSM--NQSSIAQDRGYMQR 755
Query: 1431 QPSPFQLSASVPKSFFS-KQPVRNKHPTG 1458
P Q S+ P S S +QP + TG
Sbjct: 756 NPQMPQYSSPQPGSALSPRQPSGGQIHTG 784
Score = 50.4 bits (119), Expect = 1e-05
Identities = 119/568 (20%), Positives = 180/568 (31%), Gaps = 100/568 (17%)
Query: 1059 SEPKTEQESITPGGRPPYRSNA---PWQWSGPASHNSLPASKWATPTTPGHAQSLSRPLK 1115
+EP + + G RP +N P G +S A P A +P
Sbjct: 96 AEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYG 155
Query: 1116 QTP-IVPFRESQPLHSKRPVSFPETPYTVSPAGADRVPPYRQPSGSFSTPGSATYVRYKP 1174
++P V + H + + G + PY P + G +
Sbjct: 156 RSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSY 215
Query: 1175 SPERYTAAPHPLLSLDPHFSHDGTSSGDSSSGGLTSQESTMERQKPEPLWHVPAQARLSA 1234
P R +A P P P ++ G SG + S KP P A + S+
Sbjct: 216 YPNR-SAYPPPA----PAYALSSPRGGTPGSGAAAAAGS-----KPPPSSSASASSSSSS 265
Query: 1235 IAGSSGNKHPSRQDAAGKDSPNRHSKGEPQYSSHSSSNTLSSNASSSHSDDRWFDPLDPL 1294
A R A G P+ G PQ ++ + N L ++ SS+ +
Sbjct: 266 FA-------QQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGY------- 311
Query: 1295 EPEQDPLSKGGSSDSGIDTTLYTSSPSCMSLAKAPRPA---------KPHKPPGSMGLCG 1345
P D GG D G + C A A A + H P S G G
Sbjct: 312 -PGGD--YSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSG 368
Query: 1346 GGREAAGR----SHHADRRREVSPAPAVAGQSKGYRPKLYSSGSSTPTGLAG---GSRDP 1398
GG + R S D+ ++ P P G + + + SG G G GS+ P
Sbjct: 369 GGGQPLARTPQPSSPMDQMGKMRPQP-YGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP 427
Query: 1399 PRQPSDMGSRV----------------------GY---------------PAQVYKTASA 1421
R P M R GY P Q S
Sbjct: 428 QRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQ 487
Query: 1422 ETPRPSQLAQPSPFQLSASVPKSFFSKQPVRNKHPTGWKRTEEPPPRPLPFSDPKKQVDT 1481
+ P + AQPS Q S P S QP ++ P+ + + P P P Q
Sbjct: 488 QPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPS--QPPHQQSPAPYPSQQSTTQQHP 545
Query: 1482 NTKNVFGQPRLRASLRDLRSPRKNYKSTIEDDLKKLIIMDNLGPEQERDTGQSPQKGLQR 1541
++ + QP+ ++ + + P++ ST+ P+ + Q QR
Sbjct: 546 QSQPPYSQPQAQSPYQQ-QQPQQPAPSTLSQQAAY--------PQPQSQQSQQTAYSQQR 596
Query: 1542 TLSDESLCSGRREPSFASPAGLEPGLPS 1569
+ L + SF S A P + S
Sbjct: 597 FPPPQEL----SQDSFGSQASSAPSMTS 620
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 50.4 bits (119), Expect = 1e-05
Identities = 99/456 (21%), Positives = 158/456 (34%), Gaps = 82/456 (17%)
Query: 1043 DGTPRRGWPETYDMNTSEPKTEQESI--------TPGGRPPYRSNAPWQWSGPASHNS-L 1093
+ T + WP + D + P T + +P P +A G + ++ +
Sbjct: 4468 ESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTV 4527
Query: 1094 PASKWATPTTPGHAQSLSRPLKQ-----------TPIVPFRESQPLHSK---RPVSFPET 1139
+S AT TTP A+S + L + T + F ES + S T
Sbjct: 4528 HSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSST 4587
Query: 1140 PYTVSPAGADRVPPYRQPSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTS 1199
+T+S A + +P+ S+PGS + P+ T + S H S D T
Sbjct: 4588 THTISSAPSTTSALVEEPTSYHSSPGSTATTHF---PDSSTTSGRSEESTASHSSQDATG 4644
Query: 1200 S-------------GDSSSGGLTSQESTMERQKPEPLWHVPAQARLSAIAGSSGNKHPSR 1246
+ G+S++ ++S +ME P + S SS + P+
Sbjct: 4645 TIVLPARSTTSVLLGESTTSPISS--GSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTT 4702
Query: 1247 QDAAGKDSPNRHSKGEPQYSSHSSSNTLSSNASSS-----------HSDDRWFDPLDPLE 1295
+A + R + +SS ++ T S A S+ HS + E
Sbjct: 4703 HFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPE 4762
Query: 1296 PEQDPLSKGGSSDSGIDTTLYTSSPSCMSLAKAPRPAKPHKPPGSM--------GLCGGG 1347
S S TT SSP + A P H PGS+ G
Sbjct: 4763 SSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGR 4822
Query: 1348 REAAGRSHHADRRREVSPAPA---VAGQ---------SKGYRPKLYSSGSSTP------T 1389
E + SH + ++P PA +G+ S G +S ++TP T
Sbjct: 4823 SEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKST 4882
Query: 1390 GLAGGSRDPPR--QPSDM--GSRVGYPAQVYKTASA 1421
L SR P + P+ M S G P +Y A +
Sbjct: 4883 ILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAES 4918
Score = 46.2 bits (108), Expect = 3e-04
Identities = 154/755 (20%), Positives = 240/755 (31%), Gaps = 148/755 (19%)
Query: 1043 DGTPRRGWPETYDMNTSEPKTEQESI--------TPGGRPPYRSNAPWQWSGPASHN--- 1091
+ T + WP + D + P T + +P P +A G + +
Sbjct: 3385 ESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTV 3444
Query: 1092 -SLPASKWATPT------------------TPGHAQSLSRPLKQTPIVPFRESQPLHSKR 1132
S P + TP+ +PG Q++ P T ES HS
Sbjct: 3445 HSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHS-- 3502
Query: 1133 PVSFPETPYTVSPAGADRVPPYRQPSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPH 1192
T +T+S A + +P+ S+PGS + P+ T + S H
Sbjct: 3503 -----STTHTISSAPSTTSALVEEPTSYHSSPGSTATTHF---PDSSTTSGRSEESTASH 3554
Query: 1193 FSHDGT-----------------------SSGDSSSGGLTSQESTMERQKPEPLWHVPAQ 1229
S D T SSG + L +T + +H +
Sbjct: 3555 SSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPR 3614
Query: 1230 ARLSAIAGSSGNKHPSRQDAAGKDSPNRHSK-GEPQYSSHSSSNT---LSSNASSSHSD- 1284
+ + ++ +S + ++S HS+ G ++ S T LS ++++SHS
Sbjct: 3615 SPATTLSPAS-----TTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 3669
Query: 1285 ---DRWFDPLDPLEPEQDPLSKGGSSDSG-IDTTLYTSSPSCMSLAKAPRPAKPHKPPGS 1340
D P S S SG DT L S + +S + H PGS
Sbjct: 3670 GSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQ--ESTTFHSSPGS 3727
Query: 1341 --------MGLCGGGREAAGRSHHA--DRRREVSPA----PAVAGQSKGYRPKLYS---- 1382
G EA+ R H + R +SPA P + G+S ++ S
Sbjct: 3728 THTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTT 3787
Query: 1383 -SGSSTPTGLAGGSRDPPRQPSDMGSRVGYPAQVYKTASAETPRPSQLAQPSPFQLSASV 1441
S ST T S R P + +PA + +E S + SP S +
Sbjct: 3788 PSPPSTATAPVEESTTYHRSPGSTPT-THFPASSTTSGHSE---KSTIFHSSP-DASGTT 3842
Query: 1442 PKSFFSKQPVRNKHPTGWKRTEEPPPRPLPFSDPKKQVDTNTKNVFGQPRLRASLRDLRS 1501
P S S R + T LP S + + + PR S S
Sbjct: 3843 PSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPR---SPTTTLS 3899
Query: 1502 PRKNYKSTIEDDLKKLIIMDNLGPEQERDTGQSPQKGLQRTLSDESLCSGRREPSFASPA 1561
P M +LG +E T +S T+S S + +
Sbjct: 3900 PAS---------------MTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVY 3944
Query: 1562 GLEPGLPSDVLFTSTCAFPSSTLPARRQHQHPHPPVGPGAT-------PAAGSGFPEKKS 1614
PG T T FP ST + R+ + P +T + SG E+ +
Sbjct: 3945 SSSPG------STETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEEST 3998
Query: 1615 TISASELSLADGRDRPLRRLDPGLMPLPDTAAGLEWSSLVNAAKAYEVQRAVSLFSLNDP 1674
S S G L D G E S+ ++ + S
Sbjct: 3999 AFPGSPASTQTGLPATLTTADLG-----------EESTTFPSSSGSTGTKLSPARSTTSG 4047
Query: 1675 ALSPDIPPAHSPVHSHLSLERGPPTPRTTPTMSEE 1709
+ P SP + + G P TTP++SE+
Sbjct: 4048 LVGESTPSRLSPSSTETTTLPGSP---TTPSLSEK 4079
Score = 45.4 bits (106), Expect = 5e-04
Identities = 156/731 (21%), Positives = 242/731 (33%), Gaps = 128/731 (17%)
Query: 1043 DGTPRRGWPETYDMNTSEPKTEQESITPG----GRPPYRSNAPWQWSGPASHNSLPASKW 1098
+ T WP + D + P T + P G P S S ++ + L
Sbjct: 773 ESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPS--SIPTTHISARSTTSGLVEEST 830
Query: 1099 ATPTTPGHAQSLSRPLKQTPIVPFRESQPLHSKRPVSFPETPYTVSPAGADRVPPYRQPS 1158
++PG Q++ P T ES HS T +T+S A + +P+
Sbjct: 831 TYHSSPGSTQTMHFPESDTTSGRGEESTTSHS-------STTHTISSAPSTTSALVEEPT 883
Query: 1159 GSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTSS-------------GDSSS 1205
S+PGS + P+ T + S H S D T + G+S++
Sbjct: 884 SYHSSPGSTATTHF---PDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT 940
Query: 1206 GGLTSQESTMERQKPEPLWHVPAQARLSAIAGSSGNK-----HPSRQDAAGKDSPNRHSK 1260
++S +ME P + S SS P+ ++G + S+
Sbjct: 941 SPISS--GSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSR 998
Query: 1261 GEP------QYSSHSSSNTLSSNASSSHSDDRWFD-PLDPLE-----PEQDPLSKGGSSD 1308
P + +++ LS ++++SHS D L P P Q+ + SS
Sbjct: 999 SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSG 1058
Query: 1309 SGIDTTLYTSSPSCMSLAKAPRPAKPHKPPGS--------MGLCGGGREAAGRSHHA--D 1358
S DT L S + +S + H PGS G EA+ R H +
Sbjct: 1059 S-TDTALSPGSTTALSFGQ--ESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS 1115
Query: 1359 RRREVSPA----PAVAGQSKGYRPKLYS-----SGSSTPTGLAGGSRDPPRQPSDMGSRV 1409
R +SPA P + G+S ++ S S ST T S R P +
Sbjct: 1116 PRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPT-T 1174
Query: 1410 GYPAQVYKTASAETPRPSQLAQPSPFQLSASVPKSFFSKQPVRNKHPTGWKRTEEPPPRP 1469
+PA + +E S + SP S + P S S R + T
Sbjct: 1175 HFPASSTTSGHSE---KSTIFHSSP-DASGTTPSSAHSTTSGRGESTTSRISPGSTEITT 1230
Query: 1470 LPFSDPKKQVDTNTKNVFGQPRLRASLRDLRSPRKNYKSTIEDDLKKLIIMDNLGPEQER 1529
LP S + + + PR S SP M +LG +E
Sbjct: 1231 LPGSTTTPGLSEASTTFYSSPR---SPTTTLSPAS---------------MTSLGVGEES 1272
Query: 1530 DTGQSPQKGLQRTLSDESLCS-GRREPS---FASPAGLEPGLPSDVLFTSTCAFPSSTLP 1585
T +S T+S S + G E S ++S G T T FP ST
Sbjct: 1273 TTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRG----------STETTVFPHSTTT 1322
Query: 1586 ARRQHQHPHPPVGPGAT-------PAAGSGFPEKKSTISASELSLADGRDRPLRRLDPGL 1638
+ + P +T + SG E+ + S S G L D G
Sbjct: 1323 SVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLG- 1381
Query: 1639 MPLPDTAAGLEWSSLVNAAKAYEVQRAVSLFSLNDPALSPDIPPAHSPVHSHLSLERGPP 1698
E S+ ++ + S + P SP + + G P
Sbjct: 1382 ----------EESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSP 1431
Query: 1699 TPRTTPTMSEE 1709
TTP++SE+
Sbjct: 1432 ---TTPSLSEK 1439
Score = 41.6 bits (96), Expect = 0.007
Identities = 153/741 (20%), Positives = 254/741 (34%), Gaps = 123/741 (16%)
Query: 1057 NTSEPKTEQESITPGGRPPYRSNAPWQWSGP---ASHNSLPASKWATPTTPGHAQS---- 1109
+T+ TE+ + PG ++ P + + P+S +T TT A+S
Sbjct: 2431 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSG 2490
Query: 1110 ---------LSRPLKQTPIVPFRESQPLHSKRPVSFPETPY----TVSPAGADRVPPYRQ 1156
LS +T +P + P S++ +F +P T+SPA +
Sbjct: 2491 LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEE 2550
Query: 1157 PSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTSSGDSSSGGLTSQESTME 1216
S S S PGS + S + H S S D T S++ SQEST
Sbjct: 2551 SSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTS 2610
Query: 1217 RQKPEPLWHVPAQARLSAIAGSSGNKHPSRQDAAGKDSPNRHSKGEPQYSSHSSSNTLSS 1276
P + +A+ + G++S HS +++ +T SS
Sbjct: 2611 HSSPGSTDTALSPGSTTAL-------------SFGQESTTFHSSPGSTHTTLFPDSTTSS 2657
Query: 1277 N--ASSSHSDDRWFDPLDPLEP--EQDPLSKGGSSDSGIDTTLYTSSPSCMSLAKAP--R 1330
+S+ P L P P +G S+ ++PS S A AP
Sbjct: 2658 GIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEE 2717
Query: 1331 PAKPHKPPGS--------MGLCGGGREAAGRSHHADRRREVSPAPA---VAGQSKGYRPK 1379
H+ PGS G E + H + +P+ A +G+ + +
Sbjct: 2718 STTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR 2777
Query: 1380 LYSSGSSTPTGLAGGSRDP------------PRQPS---------------DMGSRVGYP 1412
+ S GS+ T L G + P PR P+ + + P
Sbjct: 2778 I-SPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQP 2836
Query: 1413 AQVYKTASAETPRPSQLAQPSPFQLSASVPKSFFSKQPVRNKHPTGWKRTEEPPPRPLPF 1472
+ T S + L++ S S+S P S ++ V + T R EEP
Sbjct: 2837 GSTHSTVSPASTTTPGLSEESTTVYSSS-PGS--TETTVFPRSTTTSVRGEEPT------ 2887
Query: 1473 SDPKKQVDTNTKNVFGQPRLRASLRDLRSPRKNYKSTIEDDLKKLIIMDNLGPEQERDTG 1532
+ + T+T +F + + L + + ++ + L + +LG E
Sbjct: 2888 TFHSRPASTHT-TLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPS 2946
Query: 1533 QSPQKG--LQRTLSDESLCSGRREPSFASPAGLE----PGLP--------SDVLFTS--- 1575
S G L S S G PS SP+ E PG P S +TS
Sbjct: 2947 SSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS 3006
Query: 1576 --TCAFPSSTLPARRQHQHPHPPVGPGATPAAGSGFPEKKSTISASELSLADGRDRPLRR 1633
P++T + + PG+T + FP+ +T S+ A +
Sbjct: 3007 PDATLSPATTTSSGVSEESSTSHSQPGSTHT--TAFPDSTTTSGLSQEPTASHSSQ--GS 3062
Query: 1634 LDPGLMPLPDTAAGLEWSSLVNAAKAYEVQRAVSLFSLNDPALSPDIPPAHSPVHS---- 1689
+ L P TA+ L S + + + + L D ++ + A +P HS
Sbjct: 3063 TEATLSPGSTTASSLGQQSTTFHSSPGDTETTL----LPDDTITSGLVEASTPTHSSTGS 3118
Query: 1690 -HLSLERGPPTPRTTPTMSEE 1709
H +L P T+ + EE
Sbjct: 3119 LHTTL---TPASSTSAGLQEE 3136
Score = 41.2 bits (95), Expect = 0.009
Identities = 147/726 (20%), Positives = 230/726 (31%), Gaps = 128/726 (17%)
Query: 1065 QESITPGGRPPYRSNAPWQWSGPA--SHNSLPASKWATPTTPGHAQSLSRPLKQTPIVPF 1122
+ES T P + P PA + + L A ++PG Q++ P T
Sbjct: 1882 EESTTVHSSPVATATTP----SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRS 1937
Query: 1123 RESQPLHSKRPVSFPETPYTVSPAGADRVPPYRQPSGSFSTPGSATYVRYKPSPERYTAA 1182
ES+ HS T +T+S + +P+ S+PGS + P+ T +
Sbjct: 1938 EESRTSHS-------STTHTISSPPSTTSALVEEPTSYHSSPGSTATTHF---PDSSTTS 1987
Query: 1183 PHPLLSLDPHFSHDGTSS--------------------------------GDSSSGGLTS 1210
S H S D T + G +++ GL+
Sbjct: 1988 GRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE 2047
Query: 1211 QESTMERQKPEPLWHV-PAQARLSAIAGSSGNKHP---SRQDAAGKDSPNRHSKGEPQYS 1266
+ +T P + PA S ++ S H S A DS +
Sbjct: 2048 KSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTT 2107
Query: 1267 SHSSSNTL--------------SSNASSSHSDDRWFDPLDPLEPEQDPLSKGG------- 1305
SHSS + S +++SHS D L P G
Sbjct: 2108 SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTD--TALSPGSTTALSFGQESTTFH 2165
Query: 1306 SSDSGIDTTLYTSSPSCMSLAKAP--------RPAKPHKPPGSMGLCGGGREAAGRSHHA 1357
SS TTL+ S + + +A P P S G A ++H A
Sbjct: 2166 SSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPA 2225
Query: 1358 DRRREVSPAPAVAG---------QSKGYRPKLYSSGSSTPTGLAGGSRDPPRQPSDMGSR 1408
SP +S G P + SST +G + S P G+
Sbjct: 2226 STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTT 2285
Query: 1409 VGYPAQVYKTASAETPRPSQLAQPSPFQLSASVPKSFFSKQPVRNKHPTGWKRTEEPPPR 1468
P+ + T S + P +++ ++P S + P ++ T + + P
Sbjct: 2286 ---PSSAHSTTSGRGESTTSRISPGSTEIT-TLPGS--TTTPGLSEASTTFYSSPRSPTT 2339
Query: 1469 PL-PFSDPKKQV---DTNTKNVFGQPRLRASLRDLRSPRKNYKSTIEDDLKKLIIMDNLG 1524
L P S V T +++ G S +P + +ST +
Sbjct: 2340 TLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVF 2399
Query: 1525 PE--------QERDTGQSPQKGLQRTL-SDESLCSGRREPSFA---SPAGLEPGLPSDVL 1572
P +E T S TL +++S SG E S A SPA + GLP+ L
Sbjct: 2400 PRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPA-TL 2458
Query: 1573 FTSTCAFPSSTLPARRQHQHPH-PPVGPGATPAAGSGFPEKKSTISASELSLADGRDRPL 1631
T+ S+T P+ P + G P + S S +L P
Sbjct: 2459 TTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPS 2518
Query: 1632 ------------RRLDPGLMPLPDTAAGLEWSSLVNAAKAYEVQRAVSLFSLNDPALSPD 1679
R D L P T++G+ S + ++ S P LS
Sbjct: 2519 LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRH 2578
Query: 1680 IPPAHS 1685
+HS
Sbjct: 2579 STTSHS 2584
Score = 39.7 bits (91), Expect = 0.026
Identities = 135/633 (21%), Positives = 215/633 (33%), Gaps = 70/633 (11%)
Query: 1116 QTPIVPFRESQPLHSKRPVSFPETPY----TVSPAGADRVPPYRQPSGSFSTPGSATYVR 1171
+T +P + P S++ +F +P T+SPA + + S S PGS
Sbjct: 2032 ETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTA 2091
Query: 1172 YKPSPERYTAAPHPLLSLDPHFSHDGTSSGDSSSGGLTSQESTMERQKPEPLWHVPAQAR 1231
+ S + H S S D T S++ SQEST P +
Sbjct: 2092 FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGS 2151
Query: 1232 LSAIA---------GSSGNKH----PSRQDAAG--KDSPNRHSK-GEPQYSSHSSSNTL- 1274
+A++ S G+ H P ++G + S HS G P+ + +S+T
Sbjct: 2152 TTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP 2211
Query: 1275 ----SSNASSSHSDDRWFDPLDP---LEPEQDPL----SKGGSSDSGIDTTLYTSSPSCM 1323
S A +H P P P ++ S G + + + TS S
Sbjct: 2212 GLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK 2271
Query: 1324 SLAKAPRPAKPHKPPGSMGLCGGGREAAGRSHHADRRREVSPAP---AVAGQSKGYRPKL 1380
S P P S GR + S + E++ P G S+
Sbjct: 2272 STIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEA-STTF 2330
Query: 1381 YSSGSSTPTGLAGGSRDPPRQPSDMGSRVGYPAQVYKTASAETPRPSQLAQPSPFQLSAS 1440
YSS S T L+ S + + P + T S + L++ S S+S
Sbjct: 2331 YSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSS 2390
Query: 1441 VPKSFFSKQPVRNKHPTGWKRTEEPPPRPLPFSDPKKQVDTNTKNVFGQPRLRASLRDLR 1500
P S ++ V + PT R EEP + + T+T +F + + L +
Sbjct: 2391 -PGS--TETTVFPRTPTTSVRGEEPT------TFHSRPASTHT-TLFTEDSTTSGLTEES 2440
Query: 1501 SPRKNYKSTIEDDLKKLIIMDNLGPEQERDTGQSPQKG--LQRTLSDESLCSGRREPSFA 1558
+ ++ + L + +LG E S G L S S G PS
Sbjct: 2441 TAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRL 2500
Query: 1559 SPAGLE----PGLP--------SDVLFTS-----TCAFPSSTLPARRQHQHPHPPVGPGA 1601
SP+ E PG P S +TS P++T + + PG+
Sbjct: 2501 SPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGS 2560
Query: 1602 TPAAGSGFPEKKSTISASELSLADGRDRPLRRLDPGLMPLPDTAAGLEWSSLVNAAKAYE 1661
T + FP+ +T S S D L+P T +G S + +
Sbjct: 2561 THT--TAFPDSTTTPGLSRHSTTSHSSP--GSTDTTLLPASTTTSGPSQESTTSHSSPGS 2616
Query: 1662 VQRAVSLFSLNDPALSPDIPPAH-SPVHSHLSL 1693
A+S S + + H SP +H +L
Sbjct: 2617 TDTALSPGSTTALSFGQESTTFHSSPGSTHTTL 2649
Score = 36.6 bits (83), Expect = 0.22
Identities = 65/318 (20%), Positives = 108/318 (33%), Gaps = 51/318 (16%)
Query: 1057 NTSEPKTEQESITPGGRPPYRSNAPWQWSGP---ASHNSLPASKWATPTTPGHAQS---- 1109
+T+ TE+ + PG ++ P + + P+S +T TT A+S
Sbjct: 2905 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSG 2964
Query: 1110 ---------LSRPLKQTPIVPFRESQPLHSKRPVSFPETPY----TVSPAGADRVPPYRQ 1156
LS +T +P + P S++ +F +P T+SPA +
Sbjct: 2965 LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEE 3024
Query: 1157 PSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTSSGDSSSGGLTSQESTME 1216
S S S PGS + S + P S S + T S S++ Q+ST
Sbjct: 3025 SSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTF 3084
Query: 1217 RQKP--EPLWHVPAQARLSAIAGSSGNKHPSRQDAAGKDSPNRHSKGEPQYSSHSSSNTL 1274
P +P S + +S +P S G + +S+T
Sbjct: 3085 HSSPGDTETTLLPDDTITSGLVEAS--------------TPTHSSTGSLHTTLTPASSTS 3130
Query: 1275 SSNASSSHSDDRWFDPLDPLEPEQDPLSKGGSSDSGIDTTLYTSSP----------SCMS 1324
+ S + W P + P G ++ +T Y S P S +
Sbjct: 3131 AGLQEESTTFQSW-----PSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTT 3185
Query: 1325 LAKAPRPAKPHKPPGSMG 1342
L ++ H PG+ G
Sbjct: 3186 LGRSEESTTVHSSPGATG 3203
Score = 36.6 bits (83), Expect = 0.22
Identities = 70/306 (22%), Positives = 101/306 (33%), Gaps = 56/306 (18%)
Query: 1042 EDGTPRRGWPETYDMNTSEPKTEQESITPGGRPPYRSNAPWQWSGPASHNSLPASKWATP 1101
E+ T + WP + D S P T + +++S P+S TP
Sbjct: 4218 EESTTFQSWPSSSDTTPSPPSTTAVPVEVS----------------TTYHSRPSS---TP 4258
Query: 1102 TTPGHAQSLSRPLKQTPIVPFRESQPLHSKRPVS----FPETPYTVSPAGADRVPPYRQP 1157
TT A S T + ES +HS + FP T G P
Sbjct: 4259 TTHFSASS-------TTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPI--S 4309
Query: 1158 SGSFST---PGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTSSGDSSSGGLTSQEST 1214
SGS T PGS T + ++P S D T S S++ S+EST
Sbjct: 4310 SGSTETTALPGSTTTAGLSEKSTTFYSSPR---------SPDTTLSPASTTSSGVSEEST 4360
Query: 1215 MERQKPEPLWHVPAQARLSAIAGSSGNKHPSRQDAAGKD------SPNRHSKGEPQYSSH 1268
+P + H A + + G S S D S S G + H
Sbjct: 4361 TSHSRPGSM-HTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFH 4419
Query: 1269 SS-----SNTLSSNASSSHSDDRWFDPLDPLEPEQDPLSKGGSSDSGIDTTLYTSSPSCM 1323
SS + L N ++S + LS GS+ ++T + S P+
Sbjct: 4420 SSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSK 4479
Query: 1324 SLAKAP 1329
AP
Sbjct: 4480 DTTPAP 4485
Score = 35.8 bits (81), Expect = 0.38
Identities = 135/661 (20%), Positives = 231/661 (34%), Gaps = 97/661 (14%)
Query: 1116 QTPIVPFRESQPLHSKRPVSFPETPY----TVSPAGADRVPPYRQPSGSFSTPGSATYVR 1171
+T +P + P S++ +F +P T+SPA + + S S PGS
Sbjct: 3589 ETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTA 3648
Query: 1172 YKPSPERYTAAPHPLLSLDPHFSHDGTSSGDSSSGGLTSQESTMERQKPEPLWHVPAQAR 1231
+ S + H S S D T S++ +SQEST H + +
Sbjct: 3649 FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTS--------HSSSGST 3700
Query: 1232 LSAIAGSSGNKHPSRQDAAGKDSPNRHSKGEPQYSSHSSSNTLSSN--ASSSHSDDRWFD 1289
+A++ S + + G++S HS +++ +T SS +S+
Sbjct: 3701 DTALSPGS-----TTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS 3755
Query: 1290 PLDPLEP--EQDPLSKGGSSDSGIDTTLYTSSPSCMSLAKAP--RPAKPHKPPGS----- 1340
P L P P +G S+ ++PS S A AP H+ PGS
Sbjct: 3756 PRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTH 3815
Query: 1341 ---MGLCGGGREAAGRSHHADRRREVSPAPA---VAGQSKGYRPKLYSSGSSTPTGLAGG 1394
G E + H + +P+ A +G+ + ++ S GS+ T L G
Sbjct: 3816 FPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRI-SPGSTEITTLPGS 3874
Query: 1395 SRDP------------PRQPSDMGS-------RVGYPAQVYKT---ASAETPRPSQLAQP 1432
+ P PR P+ S VG + ++ ++ T P+ P
Sbjct: 3875 TTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTP 3934
Query: 1433 SPFQLSASVPKSFFSKQPVRNKHPTGWKRTEEPPPRPLPFSDPKKQVDTNTKNVFGQPRL 1492
+ S +V +S P + + T R P + + T+T +F +
Sbjct: 3935 GLSEESTTV----YSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHT-TLFTEDST 3989
Query: 1493 RASLRDLRSPRKNYKSTIEDDLKKLIIMDNLGPEQERDTGQSPQKG--LQRTLSDESLCS 1550
+ L + + ++ + L + +LG E S G L S S
Sbjct: 3990 TSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLV 4049
Query: 1551 GRREPSFASPAGLE----PGLP--------SDVLFTS-----TCAFPSSTLPARRQHQHP 1593
G PS SP+ E PG P S +TS P++T + +
Sbjct: 4050 GESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESS 4109
Query: 1594 HPPVGPGATPAAGSGFPEKKSTISASELSLADGRDRPLRRLDPGLMPLPDTAAGLEWSSL 1653
PG+T + FP+ +T S+ + + L P TA+ L S
Sbjct: 4110 TSHSQPGSTHT--TAFPDSTTTSGLSQEPTTSHSSQ--GSTEATLSPGSTTASSLGQQST 4165
Query: 1654 VNAAKAYEVQRAVSLFSLNDPALSPDIPPAHSPVHS-----HLSLERGPPTPRTTPTMSE 1708
+ + + + L D ++ + A +P HS H +L P T+ + E
Sbjct: 4166 TFHSSPGDTETTL----LPDDTITSGLVEASTPTHSSTGSLHTTL---TPASSTSTGLQE 4218
Query: 1709 E 1709
E
Sbjct: 4219 E 4219
Score = 35.4 bits (80), Expect = 0.50
Identities = 151/752 (20%), Positives = 242/752 (32%), Gaps = 122/752 (16%)
Query: 1057 NTSEPKTEQESITPGGRPPYRSNAPWQWSGP---ASHNSLPASKWATPTTPGHAQS---- 1109
+T+ TE+ + PG ++ P + + P+S +T T A+S
Sbjct: 1348 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG 1407
Query: 1110 ---------LSRPLKQTPIVPFRESQPLHSKRPVSFPETPY----TVSPAGADRVPPYRQ 1156
LS +T +P + P S++ +F +P T+SPA +
Sbjct: 1408 LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEE 1467
Query: 1157 PSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTSSGDSSSGGLTSQESTME 1216
S S S PGS + S + P S S + T S S++ Q+ST
Sbjct: 1468 SSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTF 1527
Query: 1217 RQKP--EPLWHVPAQARLSAIA-------GSSGNKH----PSRQDAAG------------ 1251
P +P S + S+G+ H P+ +AG
Sbjct: 1528 HSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWP 1587
Query: 1252 -----------------KDSPNRHSKGEPQYSSH--SSSNTL--SSNASSSHSD------ 1284
+ S HS+ ++H +SS TL S +++ HS
Sbjct: 1588 SSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGT 1647
Query: 1285 ----DRWFDPLDPLEPEQDPLSKGGSSDSGI--DTTLYTSSPSCMSLAKAPRPAKPHKPP 1338
R + EP P+S G + + + TT S + +PR P
Sbjct: 1648 ALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP 1707
Query: 1339 GSMGLCGGGREAAGR-----SHHADRRREVSPAPAVAGQSKGYRPKLYSSGSSTPTGLAG 1393
S G E+ S H + P V+ +S +SS ST T L+
Sbjct: 1708 ASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTA----SHSSPGSTDTTLSP 1763
Query: 1394 GSRDPPRQPSDMGSRVGYPAQVYKTASAETPRPSQLAQPS-PFQLSASVPKSFFSK--QP 1450
GS + + P T + S L + S P S P + S
Sbjct: 1764 GSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGST 1823
Query: 1451 VRNKHPT---GWKRTEEPPPRPLPFSDPKKQVDTNTK-NVFGQPRLRASLRDLRSPRKNY 1506
R T W +++ P P + ++ T + + P S R
Sbjct: 1824 TRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEE 1883
Query: 1507 KSTIEDDLKKLIIMDNLGPEQERDTG---------QSPQKGLQRTLSDESLCSGRREPSF 1557
+T+ + P + +G SP + S SGR E S
Sbjct: 1884 STTVHS--SPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESR 1941
Query: 1558 ASPAGLEPGLPSDVLFTSTCAFPSSTLPARRQHQHPHPPVGPGATPAAGSGFPEKKSTIS 1617
S + T T + P ST A + + PG+T A + FP+ +T
Sbjct: 1942 TSHSST----------THTISSPPSTTSALVEEPTSYHS-SPGST--ATTHFPDSSTTSG 1988
Query: 1618 ASELSLADGRDRPLRRLDPGLMPLPDTAAGLEWSSLVNAAKAYEVQRAVSLFSLNDPALS 1677
SE S A + ++P T + L S + + ++ S P LS
Sbjct: 1989 RSEESTASHSSQD--ATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLS 2046
Query: 1678 PDIPPAHSPVHSHLSLERGPPTPRTTPTMSEE 1709
HS S + P T+ +SEE
Sbjct: 2047 EKSTTFHSSPRSPATTL--SPASTTSSGVSEE 2076
Score = 34.7 bits (78), Expect = 0.85
Identities = 76/357 (21%), Positives = 123/357 (34%), Gaps = 54/357 (15%)
Query: 1085 SGPASHNSLPASKWATPTTPGHAQSLSRPLK----QTPIVPFRESQPLHSKRPVSFPETP 1140
S P + + P+S A TT G +S + + + +P + P S+ +F +P
Sbjct: 1194 SSPDASGTTPSS--AHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSP 1251
Query: 1141 Y----TVSPAGADRVPPYRQPSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPHFSHD 1196
T+SPA + + + S S PGS + P + P S +
Sbjct: 1252 RSPTTTLSPASMTSLGVGEESTTSRSQPGSTH------------STVSPASTTTPGLSEE 1299
Query: 1197 GTSSGDSSSGGLT------SQESTMERQKPEPLWHVPAQARLSAIAGSSGNKHPSRQDAA 1250
T+ SS G S +++ ++P PA + S + + A
Sbjct: 1300 STTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTA 1359
Query: 1251 GKDSPNRHSKGEPQYSSHSSSNTLSSN-ASSSHSDDRWFDPL----DPLEPEQDPLSKGG 1305
SP G P + + S+ SSS S P L E P
Sbjct: 1360 FPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTP---SR 1416
Query: 1306 SSDSGIDTTLYTSSPSCMSLAK-------APRPAKPHKPPGSMGLCGGGREAA------G 1352
S S +TT SP+ SL++ +PR P + G E++ G
Sbjct: 1417 LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPG 1476
Query: 1353 RSH-----HADRRREVSPAPAVAGQSKGYRPKLYSSGSSTPTGLAGGSRDPPRQPSD 1404
+H + ++S P + S+G S GS+T + L S P D
Sbjct: 1477 STHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGD 1533
Score = 33.9 bits (76), Expect = 1.5
Identities = 64/309 (20%), Positives = 109/309 (35%), Gaps = 33/309 (10%)
Query: 1057 NTSEPKTEQESITPGGRPPYRSNAPWQWSGP---ASHNSLPASKWATPTTPGHAQS---- 1109
+T+ TE+ + PG ++ P + + P+S +T T A+S
Sbjct: 3988 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG 4047
Query: 1110 ---------LSRPLKQTPIVPFRESQPLHSKRPVSFPETPY----TVSPAGADRVPPYRQ 1156
LS +T +P + P S++ +F +P T+SPA +
Sbjct: 4048 LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEE 4107
Query: 1157 PSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTSSGDSSSGGLTSQESTME 1216
S S S PGS + S + P S S + T S S++ Q+ST
Sbjct: 4108 SSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTF 4167
Query: 1217 RQKP--EPLWHVPAQARLSAIAGSSGNKHPSRQDAAGKDSPNRHSKGEPQYSSHSSSNTL 1274
P +P S + +S H S + + H+ P S+ +
Sbjct: 4168 HSSPGDTETTLLPDDTITSGLVEASTPTHSS--------TGSLHTTLTPASSTSTGLQEE 4219
Query: 1275 SSNASS-SHSDDRWFDPLDPLEPEQDPLSKGGSSDSGIDTTLYTSSPSCMSLAKAPRPAK 1333
S+ S S D P + + S S TT +++S + +L ++
Sbjct: 4220 STTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASST--TLGRSEESTT 4277
Query: 1334 PHKPPGSMG 1342
H PG+ G
Sbjct: 4278 VHSSPGATG 4286
Score = 31.2 bits (69), Expect = 9.4
Identities = 62/219 (28%), Positives = 77/219 (35%), Gaps = 21/219 (9%)
Query: 1078 SNAPWQWSGPASHNSLPASKWATP--TTPGHAQSLSRPLKQTPIVPFRESQPLHSKRPVS 1135
S +P Q PAS S S T + + + P T +ES HSK P S
Sbjct: 4888 SRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSK-PGS 4946
Query: 1136 FPET----PYTVSPAGADRVPPYRQPSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDP 1191
T T S + P+ QP + ST A+ S E T P +
Sbjct: 4947 TETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETT 5006
Query: 1192 HFSHDGTSSGDSSSGGLTSQESTMERQKPEPLWHV-PAQARLSAIAGSSGNKHPSRQDAA 1250
FSH T S + SQ+ST P V PA + I S H S
Sbjct: 5007 AFSHSNTMS-------IHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATG 5059
Query: 1251 GKDSPNRHSK----GEPQ--YSSHSSSNTLSSNASSSHS 1283
P R + GEP Y S S + T ASSS S
Sbjct: 5060 TTPLPARSTASDLVGEPTTFYISPSPTYTTLFPASSSTS 5098
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 49.7 bits (117), Expect = 3e-05
Identities = 109/484 (22%), Positives = 156/484 (32%), Gaps = 70/484 (14%)
Query: 1032 TVKVVIIPPFEDG--TPRRGWPETYDMNTSEPKTEQESITPGGRP----------PYRSN 1079
T VV +P ++G TP M +S PK + + P G P P +
Sbjct: 887 TPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT 946
Query: 1080 APWQWSGPASHNSLPASKWATPTTPGHAQSLSRPLKQTPIVPFRESQPLHSKRPVSFPET 1139
P GPA+ P+ KWA PT P + TP + P + P S
Sbjct: 947 PPSPKGGPAT----PSPKWA-PTPPAATPPSPKGGPATPSPKGAPTPP--AATPPSPKGG 999
Query: 1140 PYTVSPAGADRVPPYRQPSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTS 1199
P T SP GA PP P +P + + + +P T P +
Sbjct: 1000 PATPSPKGAP-TPPAVTPPSPKGSPAATPFPKGASTPPAAT----------PPSPKGSPA 1048
Query: 1200 SGDSSSGGLTSQESTMERQKPEPLWHVPAQARLSAIAGSSGNKHPSRQDAAGKDSPNRHS 1259
+ G T+ +T+ K P A L PS + SP
Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGGP-----ATPSLKGAPTPPAATPPSPKGGPATPSP---- 1099
Query: 1260 KGEPQYSSHSSSNTLSSNASSSHSDDRWFDPLDPLEPEQDPLS-KGGSSD---SGIDTTL 1315
KG P + + + A+ H P P P S KGG + G TT
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGA-------PTTPAATPPSPKGGLATPPPKGAPTTP 1152
Query: 1316 YTSSPSCMSLAKAPRP--------AKPHKPPGSMGLCG--GGREAAGRSHHADRRREVSP 1365
+ PS P P A P P G + G + + + +P
Sbjct: 1153 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212
Query: 1366 APAVAGQSKGYRPKLYSSGSSTPTGLAGGSRDPPRQPSDMGSRVGYPAQVYKTASAETP- 1424
+P A + P G +TP+ + PS G P + T A TP
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPP 1272
Query: 1425 -------RPSQLAQPSPFQLSASVPKSFFSKQPVRNKHPTGWKRTEEPPPRPLPFSDPKK 1477
P P+P ++ PK + P + PT T P P+ P + P K
Sbjct: 1273 SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA-PTPPAAT-PPSPKGSPGTPPPK 1330
Query: 1478 QVDT 1481
T
Sbjct: 1331 GAPT 1334
Score = 44.3 bits (103), Expect = 0.001
Identities = 137/595 (23%), Positives = 195/595 (32%), Gaps = 87/595 (14%)
Query: 1070 PGGRPPYRSNAPWQWSGPASHNSLPASKWATPTTPGHAQSLSRPLKQTPIVPFRESQPLH 1129
P G+P +P + AS + +A P + G LK + I P + PL
Sbjct: 600 PIGKPASSMTSPLGVNSSAS--VIKTDSYAGPDSAGPL------LKSSLITPTVAAFPLE 651
Query: 1130 SKRPVSFPETPY--------TVSP--AGADRVPPYRQP--SGSFST----PGSATYVRYK 1173
S P T T SP G + P P G+ +T P ++
Sbjct: 652 SADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVA 711
Query: 1174 PSPERYTAAPHPLLSLDPHFSHD---------GTSSGDSSSGGLTSQESTMERQKPEPLW 1224
PSP+ T AP L L P GT G G+ S S + P
Sbjct: 712 PSPQN-TCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGI-SHTSALAPVASSPKE 769
Query: 1225 HVPAQARLSAIAGSSGN--------------------KHPSRQDAAGKDSP--NRHSKGE 1262
+ SA A S G + P+++ +AG D+P N S
Sbjct: 770 CPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVS 829
Query: 1263 PQYSSHSSSNTLSSNASSSHSDDRWFDPLDPLEPEQDPLSKGGSSDSGIDTTL---YTSS 1319
P +S N+LS S S P P P+ P + S TL T +
Sbjct: 830 PVEASFLPENSLSFQGSKD-SPATTHSPTPP-SPKGAPTPSAVTPLSPKGVTLPPKETPT 887
Query: 1320 PSCMSLA---KAPRPAKPHKPPGSMGLCGGGREAAGRSHHADRRREVSPAPAVAGQSKGY 1376
PS ++L + P P + P ++A R+ A + SP+P A
Sbjct: 888 PSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKA--RATPAPKGIPASPSPKGAPTPPAA 945
Query: 1377 RPKLYSSGSSTPTGLAGGSRDPPRQPSDMGSRVGYPAQVYKTASAETPRPSQLAQPSPFQ 1436
P G +TP+ + PS G + T A TP + +P
Sbjct: 946 TPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP 1005
Query: 1437 LSASVPKSFFSKQPVRNKHPTGWKRTEEPPPRPLPFSDPKKQVDTNTKNVFGQPRLRASL 1496
A P + P + T + + PP P S T G P A+
Sbjct: 1006 KGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPK--GAPTTPAA- 1062
Query: 1497 RDLRSPRKNYKSTIEDDLKKLIIMDNLGPEQERDTGQSPQKGLQRTLSDESLCSGRREPS 1556
L SP+ LK P T SP KG T S + G P
Sbjct: 1063 -TLPSPK---GGPATPSLKG-------APTPPAATPPSP-KGGPATPSPK----GAPMPP 1106
Query: 1557 FASPAGLEPGLPSDVLFTSTCAFPSSTLPARRQHQHPHPPVGPGATPAAGSGFPE 1611
A+P + GL + P++T P+ + PP G TPAA P+
Sbjct: 1107 AATPPSPKGGLATPP-HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1160
Score = 44.3 bits (103), Expect = 0.001
Identities = 136/664 (20%), Positives = 206/664 (31%), Gaps = 101/664 (15%)
Query: 1061 PKTEQESITPGGRPPYRSNA---PWQWSGPASHNSLPASKWATPTTPGHAQSLSRPLKQT 1117
P + TP PP P P + + P S P TP + + P
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP 1271
Query: 1118 PIVPFRESQPLHSKRPVSFPETPYTVSPAGADRV-PPYRQPSGSFSTPGSATYVRYKPSP 1176
P + + P H P TP SP G PP P+ +TP S P P
Sbjct: 1272 PSLKGGLATPPHKGAPNPAVVTP--PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPP 1329
Query: 1177 ERYTAAPHPLLSLDPHFSHDGT----SSGDSSSGGLTSQES--------TMERQKPEPLW 1224
+ AP P P S GT ++ SS GG T+ S K P
Sbjct: 1330 K---GAPTPPAVTPP--SPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAM 1384
Query: 1225 HVPAQARLSAIAGSSGNK--------HPSRQDAA-----GKDSPNRHSKGEPQYSSHSSS 1271
P+ R AI G+ P + A G +P++ P + S
Sbjct: 1385 TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLK 1444
Query: 1272 NTLSSNA------SSSHSDDRWFDPLDPLEPEQDPLSKGGSSDSGIDTTLYTSSPSCMSL 1325
+++A + S D + P P++ P K ++ S T +P
Sbjct: 1445 KAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPT 1504
Query: 1326 AKAPRPAKPHKPPGSMGLCGGGREAAGRSHHADRRREVSPA--------PAVAGQSKGYR 1377
A P+ P + P + + RR ++P PA +
Sbjct: 1505 LPAVIPSSPKEVPATP---------------SSRRDPIAPTATLLSKKTPATLAPKEALI 1549
Query: 1378 PKLYSSGSSTPTGLAGGSRDPPRQPSDMGSRVGYPAQVYKTASAETPRPSQLAQP----S 1433
P + S T ++ P PS P V + P P +L P S
Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSS--KEASSPPAVTPSTYKGAPSPKELLIPPAVTS 1607
Query: 1434 PFQLSASVPKSFFSKQPVRNKHPTGWKRTEEPPP-RPLPFSD-PKKQVDTNTKNVFGQPR 1491
P A P + P + K T PP P D P K P+
Sbjct: 1608 PSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ 1667
Query: 1492 LRASLRDLRSP---RKNYKSTIEDDLKKLIIMDNLGPEQERDTGQSP-----------QK 1537
L + P ++ + + + GP+ ++ + SP K
Sbjct: 1668 ASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSK 1727
Query: 1538 GLQRTLSDESLCSGRREPSFA--------SPAGLEPGLPSDVLFTSTCAFPSSTLPARRQ 1589
G T++ L +++ S SP G S T A LP
Sbjct: 1728 GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPES 1787
Query: 1590 HQ---HPHPPVGPGATPAAGSGFPEKKSTISASELSLADGRDRPLRRLDPG-LMPL--PD 1643
P PPV P+ P K+ + +S + + +PL D L+PL P+
Sbjct: 1788 ASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPE 1847
Query: 1644 TAAG 1647
+G
Sbjct: 1848 PISG 1851
Score = 42.4 bits (98), Expect = 0.004
Identities = 146/653 (22%), Positives = 210/653 (32%), Gaps = 102/653 (15%)
Query: 1039 PPFEDGTPR-----RGWPETYDMNTSEPKTEQESITPGGRP-PYRSNAPWQWSGPA--SH 1090
PP G+P +G P T PK + + G P P + P GPA S
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099
Query: 1091 NSLPASKWATPTTP--GHAQSLSRPLKQTPIV-PFRESQPLHSKRPVSFPETPYTV--SP 1145
P ATP +P G A + TP P L + P P TP SP
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1159
Query: 1146 AGADRVPPYR-----------QPSGSFSTPGS----ATYVRYKPSPERYTAAPHPL---- 1186
G PP + P G +TP T PSP+ A P P
Sbjct: 1160 KGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1219
Query: 1187 --LSLDPHFSHDGTSSGDSSSGGLTSQESTMERQKPEPLWHVPAQARLSAIA-------G 1237
+ P S G + S G T+ +T K P P A A G
Sbjct: 1220 TPAATPP--SPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGG 1277
Query: 1238 SSGNKHPSRQDAAGKDSPNRHSKGEPQYSSHSSSNTLSSNASSSHSDDRWFDPLD--PLE 1295
+ H + A P+ KG P S + T + S P P
Sbjct: 1278 LATPPHKGAPNPAVVTPPS--PKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP 1335
Query: 1296 PEQDPLSKGGSSDSGIDTTLYTSSPSCMSLAKAPRPAKPHKPPGSMGLCGGGREAAGRSH 1355
P P S G+ TL ++PS P + PP + GG S
Sbjct: 1336 PAVTPPSPKGTP------TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPS- 1388
Query: 1356 HADRRREVSPAPAVAGQSKGYRPKLYSSGSSTPTGLAGGSRDPPRQPSDMGSRVGYPAQV 1415
+R P+P S P +TP G + D+ P +
Sbjct: 1389 --PKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATP---SKGDLTPPAVTPVSL 1443
Query: 1416 YKTASAETPR-----PSQLAQPSPFQLSASVPKSFFSKQPVRNKHPTGWKRTEEPPPRPL 1470
K + P+ PS P+ L A P S K+P K ++ P P
Sbjct: 1444 KKAPATSAPKGGPATPSSKGDPT---LPAVTPPS--PKEPPAPKQVATSSSPKKAPATPA 1498
Query: 1471 PFSDPKKQ--VDTNTKNVFGQPRLRASLRDLRSPR-----KNYKSTIEDDLKKLIIMDNL 1523
P P + ++ K V P +S RD +P K +T+ K+ +I +
Sbjct: 1499 PMGAPTLPAVIPSSPKEV---PATPSSRRDPIAPTATLLSKKTPATLAP--KEALIPPAM 1553
Query: 1524 GPEQERDTGQSPQKGLQRTLSDESLCSGRREPSFASPAGLEPGL------PSDVLFTSTC 1577
+ T P T + +E S SP + P P ++L
Sbjct: 1554 TVPSPKKTPAIP------TPKEAPATPSSKEAS--SPPAVTPSTYKGAPSPKELLIP--- 1602
Query: 1578 AFPSSTLPARRQHQHPHPPVGPGATPAAGSGFPEKKSTISASELSLADGRDRP 1630
P+ T P+ ++ P PP +P G P K T ++ ++ + +D P
Sbjct: 1603 --PAVTSPSPKEA--PTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSP 1651
Score = 41.2 bits (95), Expect = 0.009
Identities = 108/470 (22%), Positives = 146/470 (31%), Gaps = 74/470 (15%)
Query: 1036 VIIPPFEDG----TPRRGWPETYDMNTSEPKTEQESITPGGRP-PYRSNAPWQWSGPASH 1090
V+ PP G +P +G P PK + P G P P P P
Sbjct: 1291 VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLP 1350
Query: 1091 NSLPASKWATPTTPGHAQSLSRPLKQTPIVPFRESQPLHSKRPVSFPETPYTVSPAGADR 1150
+ P+SK PTTP K+ P P + P H P P +P R
Sbjct: 1351 ATTPSSKGG-PTTPSS--------KEGPTPP--AATPSHKGGPAMTPPSP--------KR 1391
Query: 1151 VPPYRQPSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTSSGDSSSGGLTS 1210
P P G ++P SP++ A P + +G ++ S G LT
Sbjct: 1392 GPAIPSPKGDPTSPAVIPL-----SPKKAPATP---------VTREGAAT--PSKGDLTP 1435
Query: 1211 QESTMERQKPEPLWHVP----------AQARLSAIAGSSGNKHPSRQDAAGKDSPNRHSK 1260
T K P P L A+ S + P+ + A SP K
Sbjct: 1436 PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP----K 1491
Query: 1261 GEPQYSSHSSSNTLSSNASSSHSD--DRWFDPLDPLEPEQDPLSKGGSSDSGIDTTLYTS 1318
P + + TL + SS + DP+ P LSK + L
Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551
Query: 1319 S---PSCMSLAKAPRPAKPHKPPGSMGLCGGGREAAGRSHHADRRREV-------SPAPA 1368
+ PS P P + P S A +E+ SP+P
Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK 1611
Query: 1369 VAGQSKGYRPKLYSSGSSTPTGLAGGSRDPPRQPSDMGSRVGYPAQVYKTASAETPRPSQ 1428
A P G +TP G PP PS + PA V A P+ S+
Sbjct: 1612 EAPTPPAVTPPSPEKGPATPAP-KGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASK 1670
Query: 1429 --LAQPSPFQLS----ASVPKSF-FSKQPVRNKHPTGWKRTEEPPPRPLP 1471
A+ P L A P+S P R T PP P P
Sbjct: 1671 GLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDP 1720
Score = 36.6 bits (83), Expect = 0.22
Identities = 132/593 (22%), Positives = 187/593 (31%), Gaps = 59/593 (9%)
Query: 1130 SKRPVSFPETPY-----TVSPAGADRVPPYRQPSGSFSTPGSATYVRYKPSPERYTAAPH 1184
+K+ + P+TP VSP A +P + S SF + + P+P AP
Sbjct: 810 TKKGSAGPDTPIGNLSSPVSPVEASFLP---ENSLSFQGSKDSPATTHSPTPPSPKGAPT 866
Query: 1185 PLLSLDPHFSHDGTSSGDSSSGGLTSQESTMERQKPEPLWHVPAQARLSAIAGSSGNKHP 1244
P S S G + T S + P+ PA + A++ +S +
Sbjct: 867 P--SAVTPLSPKGVTLPPKE----TPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK 920
Query: 1245 SRQDAAGKDSPNRHS-KGEPQYSSHSSSNTLSSNASSSHSDDRWFDPLDPLEPEQDPLS- 1302
+R A K P S KG P + + + A+ S +W P P P S
Sbjct: 921 ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPS---PKWA----PTPPAATPPSP 973
Query: 1303 KGGS---SDSGIDTTLYTSSPSCMSLAKAPRPAKPHKPPGSMGLCGGGREAAGRSHHADR 1359
KGG S G T + PS P P PP G AA
Sbjct: 974 KGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS 1033
Query: 1360 RREVSPAPAVAGQSKGYRPKLYSSGSSTPTGLAGGSRDPPRQPSDMGSRVGYPAQVYKTA 1419
+ P+ G L +TP + P PS G+ PA +
Sbjct: 1034 TPPAATPPSPKGSPAA--TPLPKGAPTTPAATLPSPKGGPATPSLKGAPTP-PAATPPSP 1090
Query: 1420 SAETPRPSQLAQPSPFQLSASVPKSFFSKQPVRNKHPTGWKRTEEPPPRPLPFSDPKKQV 1479
PS P P + PK + P + T P P+ + P K
Sbjct: 1091 KGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT--PAATPPSPKGGLATPPPKGA 1148
Query: 1480 DTNTKNVFGQPRLRASLRDLRSPRKNYKSTIEDDLKKLIIMDNLG-PEQERDTGQSPQKG 1538
T P+ + + +T L G P T SP+ G
Sbjct: 1149 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1208
Query: 1539 LQRTLSDESLCSGRREPSFASPAGLEPGLPSDVLFTSTCAFPSSTLPARRQHQHPHPPVG 1598
L S + P+ +PA P + S P T PA P P G
Sbjct: 1209 LATP-------SPKGAPT--TPAATPPSPKGGLATPSPKGAP--TTPAATP---PSPKGG 1254
Query: 1599 PGATPAAGSGFPEKKSTISASELSLADGRDRPLRRLDPGLMPLPDTAAGLEWSSLVNAAK 1658
P P G+ P +A+ SL G P + P P T + + K
Sbjct: 1255 PATPPPKGAPTPP-----AATPPSLKGGLATPPHKGAPN--PAVVTPPSPKGGPATSPPK 1307
Query: 1659 AYEVQRAVSLFSLNDPALSPDIPPAHSPVHSHLSLERGPPTPRTTPTMSEEPP 1711
A + S P SP PP P + PP+P+ TPT+ P
Sbjct: 1308 GAPTPPAATPPS---PKGSPGTPP---PKGAPTPPAVTPPSPKGTPTLPATTP 1354
Score = 34.3 bits (77), Expect = 1.1
Identities = 39/157 (24%), Positives = 58/157 (36%), Gaps = 19/157 (12%)
Query: 15 AASCGARVGDVLPGPHTGDYAPLGFWAQNGSMSQPLGESPATATATATATTRPSPTTPAM 74
AA+ + G + PH G A N ++ P P+ AT+ + +PT PA
Sbjct: 1268 AATPPSLKGGLATPPHKG--------APNPAVVTP----PSPKGGPATSPPKGAPTPPAA 1315
Query: 75 PKMGVRARVADWPPKREALREHSNPSPSQDTDGTKATKMAH-----SMRSIQNGQPPTST 129
+ PPK P + T AT + + S + PP +T
Sbjct: 1316 TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT 1375
Query: 130 PASSGSKAFHRLSRRRSKDVEFQDGWPRSPGRAFLPL 166
P+ G A S +R + G P SP A +PL
Sbjct: 1376 PSHKGGPAMTPPSPKRGPAIPSPKGDPTSP--AVIPL 1410
Score = 32.7 bits (73), Expect = 3.2
Identities = 27/101 (26%), Positives = 40/101 (39%), Gaps = 15/101 (14%)
Query: 1099 ATPTTPGHAQSLSRPLKQTPIVPFRESQPLHSKRPVSFPETPYTVSPA-------GADRV 1151
AT T P Q L +P +T ++P + + + P P SPA A++
Sbjct: 5 ATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQA 64
Query: 1152 PPYRQPSGSFSTP--------GSATYVRYKPSPERYTAAPH 1184
P+ PS STP S T + +PE T P+
Sbjct: 65 SPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPN 105
Score = 32.3 bits (72), Expect = 4.2
Identities = 31/112 (27%), Positives = 37/112 (33%), Gaps = 12/112 (10%)
Query: 27 PGPHTGDYAPLGFWAQNGSMSQPLGESPATATATATATTRPSPTTPAMPKMGVRARVADW 86
P P G P WA + P AT + P TP PK G
Sbjct: 948 PSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007
Query: 87 PPKREALREHSNPSPSQDTDGTKATKMAHSMRSIQNGQPPTSTPAS-SGSKA 137
P A+ + PSP T K A + PP +TP S GS A
Sbjct: 1008 APTPPAV---TPPSPKGSPAATPFPKGAST--------PPAATPPSPKGSPA 1048
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 49.3 bits (116), Expect = 3e-05
Identities = 78/352 (22%), Positives = 122/352 (34%), Gaps = 49/352 (13%)
Query: 1133 PVSFPETPYTVSPAGADRVPPYRQPSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPH 1192
P++ TP P+ P+ S G+ RY PS T+ H S+
Sbjct: 330 PLTAIHTPCKTEPSKF----PFPTKESQQSNFGTGEQKRYNPSK---TSNGHQSKSM--- 379
Query: 1193 FSHDGTSSGDSSSGGLTSQESTMERQKPEPLWHVPAQARLSAIAGSSGNKHPSRQDAAGK 1252
D S S G + TM R P N PS ++ G
Sbjct: 380 LKDDLKLSSSEDSDGEQDCDKTMPRSTP------------------GSNSEPSHHNSEGA 421
Query: 1253 DSPNRHSKGEPQYSSHSSSNTLSSNASSSHSDDRWFDPLDPLEPEQDPLSKGGSSDSGID 1312
D+ S +S SS+ S + SS SD +P PE +P ++ +D
Sbjct: 422 DNSRDDSS---SHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEP---PPTNKWQLD 475
Query: 1313 TTLYTSSPSCMSLAKAPRPAKPHKPPGSMGLCGGGREAAGRSHHADRRREVSPAPAVAGQ 1372
L +P +S P + P S G GRE + + D + A G+
Sbjct: 476 NWLNKVNPHKVS----PASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGR 531
Query: 1373 SKGYRPKLYSSGSSTPTG--LAGGSRDPPRQPSDMGSRVGYPAQVYKTASAETPRPSQLA 1430
K GS + G + D Q +G + P + K A+ E ++
Sbjct: 532 DS----KTIQKGSESGRGRQKSPAQSDSTTQRRTVGKK--QPKKAEKAAAEEPRGGLKIE 585
Query: 1431 QPSPFQLSASVPKSFFSKQPVRNKHPTGWKRTEEPPPRPLPFSDPKKQVDTN 1482
+P L++S+P S K + K+ + PRP ++ KK T+
Sbjct: 586 SETPVDLASSMPSS-RHKAATKGSRKPNIKKESKSSPRPT--AEKKKYKSTS 634
>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
Length = 1952
Score = 48.1 bits (113), Expect = 7e-05
Identities = 146/737 (19%), Positives = 233/737 (31%), Gaps = 116/737 (15%)
Query: 1043 DGTPRRGWPETYDMNTSEPKTEQESITPG----GRPPYRSNAPWQWSGPASHNSLPASKW 1098
+ T WP + D + P T + P G P S S ++ + L
Sbjct: 694 ESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPS--SIPTTHISARSTTSGLVEEST 751
Query: 1099 ATPTTPGHAQSLSRPLKQTPIVPFRESQPLHSKRPVSFPETPYTVSPAGADRVPPYRQPS 1158
++PG Q++ P T ES HS T +T+S A + +P+
Sbjct: 752 TYHSSPGSTQTMHFPESDTTSGRGEESTTSHS-------STTHTISSAPSTTSALVEEPT 804
Query: 1159 GSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTSS------------------ 1200
S+PGS + P+ T + S+ H S D T +
Sbjct: 805 SYHSSPGSTATTHF---PDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTT 861
Query: 1201 --------------GDSSSGGLTSQESTMERQKPEPLWHV-PAQARLSAIAGSSGNKHP- 1244
G +++ GL+ + +T P + PA S ++ S H
Sbjct: 862 SPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSR 921
Query: 1245 --SRQDAAGKDSPNRHSKGEPQYSSHSSSNTLSSNASSSHSDDRWFDPLDPLEPEQDPLS 1302
S A DS +SHSS + + + + EP P+S
Sbjct: 922 PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVG-----EPTTSPIS 976
Query: 1303 KGGSSDSGI--DTTLYTSSPSCMSLAKAPRPAKPHKPPGSMGLCGGGREAAGR-----SH 1355
G + + + TT S + +PR P S G E+ S
Sbjct: 977 SGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGST 1036
Query: 1356 HADRRREVSPAPAVAGQSKGYRPKLYSSGSSTPTGLAGGSRDPPRQPSDMGSRVGYPAQV 1415
H + P V+ +S +SS ST T L+ S + + P
Sbjct: 1037 HTTAFPGSTTMPGVSQESTA----SHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGST 1092
Query: 1416 YKTASAETPRPSQLAQPS-PFQLSASVPKSFFSK--QPVRNKHPT---GWKRTEEPPPRP 1469
T + S L + S P S P++ S R T W +++ P P
Sbjct: 1093 ETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAP 1152
Query: 1470 LPFSDPKKQVDTNTKNVFGQPRLRASLRDLRSPRKNYKSTIEDDLKKLIIMDNLGPEQER 1529
+ ++ T + G P + S +S + + P R
Sbjct: 1153 PTTTSAFVELSTTS---HGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPAR 1209
Query: 1530 DT-----------GQSPQKGLQRTLSDESLCSGRREPSFASPAGLEPGLPSDVLFTSTCA 1578
T SP + S SGR E S S + T T +
Sbjct: 1210 STTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSST----------THTIS 1259
Query: 1579 FPSSTLPARRQHQHPHPPVGPGATPAAGSGFPEKKSTISASELSLADGRDRPLRRLDPGL 1638
P ST A + + PG+ A + FPE +T SE S A G+
Sbjct: 1260 SPPSTTSALVEEPTSYHS-SPGS--IATTHFPESSTTSGRSEESTASHSSPDTN----GI 1312
Query: 1639 MPLPDTAAGLEWSSLVNAAKAYEVQRAVSLFSLNDPALSPDIPPAHSPVHSHLSLERGP- 1697
PLP A S + + + + +L A +P + + ++S R P
Sbjct: 1313 TPLP---AHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSS---SRSPD 1366
Query: 1698 ----PTPRTTPTMSEEP 1710
P T+ ++S EP
Sbjct: 1367 QTLSPASMTSSSISGEP 1383
Score = 36.2 bits (82), Expect = 0.29
Identities = 90/386 (23%), Positives = 134/386 (34%), Gaps = 58/386 (15%)
Query: 1087 PASHNSLPASKWATPT--TPGHAQSLSRPLKQTPIVPFRESQPLHSKRPVSFPETPYTVS 1144
PAS S S+ +T + PG + + P T +ES HS S T T+S
Sbjct: 1014 PASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHS----SPGSTDTTLS 1069
Query: 1145 PAGADRVPPYRQPSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDPHFSHDGTSSGDSS 1204
P + + S PGS P+ TA+ S H S + S
Sbjct: 1070 PRSTTASSLGPESTTFHSGPGSTETTLL---PDNTTASGLLEASTPVHSSTGSPRTTLSP 1126
Query: 1205 SGGLTSQ-ESTMERQKPEPLWHVPAQ-------ARLSAIAGSSGNKHPSRQDAAGKDSPN 1256
+G T Q EST + P +PA LS + S + P+ +A +
Sbjct: 1127 AGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFG 1186
Query: 1257 RHSKGEPQYSS-----------HSSSNTLSSNASSSHSDDRWFDPLDPLEPEQDPLSKGG 1305
R + +SS S+++ L +++ HS + E
Sbjct: 1187 RSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEE 1246
Query: 1306 SSDSGIDTTLYTSSPSCMSLAKAPRPAKPHKPPGSM--------GLCGGGREAAGRSHHA 1357
S S TT SSP + A P H PGS+ G E + SH +
Sbjct: 1247 SRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSS 1306
Query: 1358 DRRREVSPAPA---VAGQ---------SKGYRPKLYSSGSSTP------TGLAGGSRDPP 1399
++P PA +G+ S G +S ++TP T L SR P
Sbjct: 1307 PDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPD 1366
Query: 1400 R--QPSDM--GSRVGYPAQVYKTASA 1421
+ P+ M S G P +Y A +
Sbjct: 1367 QTLSPASMTSSSISGEPTSLYSQAES 1392
Score = 31.2 bits (69), Expect = 9.4
Identities = 62/219 (28%), Positives = 77/219 (35%), Gaps = 21/219 (9%)
Query: 1078 SNAPWQWSGPASHNSLPASKWATP--TTPGHAQSLSRPLKQTPIVPFRESQPLHSKRPVS 1135
S +P Q PAS S S T + + + P T +ES HSK P S
Sbjct: 1362 SRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSK-PGS 1420
Query: 1136 FPET----PYTVSPAGADRVPPYRQPSGSFSTPGSATYVRYKPSPERYTAAPHPLLSLDP 1191
T T S + P+ QP + ST A+ S E T P +
Sbjct: 1421 TETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETT 1480
Query: 1192 HFSHDGTSSGDSSSGGLTSQESTMERQKPEPLWHV-PAQARLSAIAGSSGNKHPSRQDAA 1250
FSH T S + SQ+ST P V PA + I S H S
Sbjct: 1481 AFSHSNTMS-------IHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATG 1533
Query: 1251 GKDSPNRHSK----GEPQ--YSSHSSSNTLSSNASSSHS 1283
P R + GEP Y S S + T ASSS S
Sbjct: 1534 TTPLPARSTASDLVGEPTTFYISPSPTYTTLFPASSSTS 1572
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 47.0 bits (110), Expect = 2e-04
Identities = 93/428 (21%), Positives = 144/428 (33%), Gaps = 75/428 (17%)
Query: 1199 SSGDSSSGGLTSQESTMERQKPEPLWHVPAQARLSAIAGSSGNKHPSRQDAAGKDSPNRH 1258
SSG S S L+S S H + R + SSG++ PS +G SP R+
Sbjct: 256 SSGSSHSPSLSSHYSDSRSPSRLSPKHRD-EGRKTGSQRSSGSRSPSPSGGSGWGSPQRN 314
Query: 1259 SKGEPQYSSHSSSNTLSSNASSSHSDDRWFDPLDPLEPEQDPLSKGGSSDSGIDTTLYTS 1318
+ +H S+HS P K S + +
Sbjct: 315 GGSGQRSGAHGG------RPGSAHS----------------PPDKPSSPSPRVRDKAAAA 352
Query: 1319 SPSCMSLAKAPRPAKPHKPPGSMGLCGGGREAAGRSHHADRRREVSPAPAVAGQSKGYR- 1377
+P+ A+ P P S G G AGR RRR S + A A + +G R
Sbjct: 353 APT--PPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRR 410
Query: 1378 ----------PKLYSSGSSTPTGLAGGSRDPPRQPSDMGSRVGYPAQVYKTASAETPRPS 1427
L + SS+ +G G+ P +P GS G+ K A PR
Sbjct: 411 PRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEP---GSERGHGGH-GKRAKERPPRAR 466
Query: 1428 QLA-QPSPFQLSASVPKSFFSKQPVRNKHPTGWKRTEEPPPRPLPFSDPKKQVDTNTKNV 1486
+ PSP R P G + P P P +S + + +++
Sbjct: 467 PASTSPSPGAHG-------------RRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSA 513
Query: 1487 FGQPRLRASLRDLRSPRKNYKSTIEDDLKKLIIMDNLGPEQERDTGQSPQKGLQRTLSDE 1546
+P + RSP KK + D G + R + + +R+ S
Sbjct: 514 EKRPHSPS-----RSPSP----------KKPLSRDKDGEGRARHSEAEATRARRRSRSYS 558
Query: 1547 SLCSGRRE-PSFASPAGLEPGLPSDVLF-----TSTCAFPSSTLPARRQHQHPHPPVGPG 1600
+ RR+ PSF P + + + +S+ + SS R + P P G
Sbjct: 559 PIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHG 618
Query: 1601 ATPAAGSG 1608
+ + G
Sbjct: 619 SYSSRSHG 626
Score = 31.6 bits (70), Expect = 7.2
Identities = 86/370 (23%), Positives = 127/370 (34%), Gaps = 58/370 (15%)
Query: 23 GDVLPGPHTGDYAPLGFWAQNGSMSQPLGESPATATATATATTRPSPTTPAMPKMGVRAR 82
G P P G + G +NG Q G + + +PS +P + A
Sbjct: 296 GSRSPSPSGG--SGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAA- 352
Query: 83 VADWPPKREALREHSNPSPSQDTDGTKATKMAHSMRSIQNGQPPTSTPASSGSKAFHRLS 142
A PP R +PS G +A A R + + + + AS A R
Sbjct: 353 -APTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSAS----APRRRG 407
Query: 143 RRRSKDVEFQDGWPRSPGRAFLPLRHRSSSEITLSECDAEDAGEPRGARHTGALPLFREY 202
RRR + PR R+ R RSSS D+G RGA G P
Sbjct: 408 RRRPRPAP-----PRGSSRSLS--RARSSS----------DSGSGRGAPGPGPEP----- 445
Query: 203 GSTSSIDVQGMPEQSFFDILNEFRSEQPDARGCQALTELLRADPGPHLMGGGGGAKGDSH 262
GS G R+++ R A T PG H GG K S
Sbjct: 446 GSERGHGGHGK------------RAKERPPRARPASTS---PSPGAHGRRGGPEGKSSSR 490
Query: 263 NGQPAKDSLLPLQPTKEKEKARKKPARGLGGGDTVDSSIFRKL-RSSKPEGEAGRSPGEA 321
+ P S ++ K+R + A + S + L R EG A S EA
Sbjct: 491 SPGPHPRS---WSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEA 547
Query: 322 DEGRSPPEASRPWVCQKSFAHFDVQSMLFDLNEAAANRVSVSQRRNTTTGASAASAASAM 381
R + P ++ D S + +A + + R S +S++S +
Sbjct: 548 TRARRRSRSYSPIRKRRR----DSPSFMEPRRITSARKRPIPYYR-----PSPSSSSSCL 598
Query: 382 ASLTASRAHS 391
+S ++R+HS
Sbjct: 599 SSDYSTRSHS 608
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,487,266
Number of Sequences: 37866
Number of extensions: 4634136
Number of successful extensions: 20804
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 631
Number of HSP's that attempted gapping in prelim test: 17646
Number of HSP's gapped (non-prelim): 3587
length of query: 1781
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1664
effective length of database: 13,817,196
effective search space: 22991814144
effective search space used: 22991814144
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.