Guide to the Human Genome
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Search of human proteins with 71044477

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|71044477 death inducer-obliterator 1 isoform b [Homo
sapiens]
         (1189 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens]     2392   0.0  
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]     2374   0.0  
gi|18375619 death inducer-obliterator 1 isoform a [Homo sapiens]     1082   0.0  
gi|18375617 death inducer-obliterator 1 isoform a [Homo sapiens]     1082   0.0  
gi|7662018 PHD finger protein 3 [Homo sapiens]                        199   1e-50
gi|47271475 SPOC domain containing 1 [Homo sapiens]                   107   7e-23
gi|90093355 jumonji C domain containing histone demethylase 1 ho...    75   5e-13
gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]       66   2e-10
gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]       66   2e-10
gi|117190342 PHD finger protein 2 [Homo sapiens]                       65   5e-10
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     64   9e-10
gi|32698700 PHD finger protein 8 [Homo sapiens]                        64   9e-10
gi|38788260 bromodomain PHD finger transcription factor isoform ...    63   1e-09
gi|38788274 bromodomain PHD finger transcription factor isoform ...    63   1e-09
gi|41350335 transcription elongation factor A (SII), 3 [Homo sap...    59   2e-08
gi|110349719 titin isoform N2-A [Homo sapiens]                         53   2e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   53   2e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    53   2e-06
gi|239749424 PREDICTED: hypothetical protein XP_002347041 [Homo ...    52   3e-06
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    52   3e-06
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    52   3e-06
gi|5803191 transcription elongation factor A 1 isoform 1 [Homo s...    52   3e-06
gi|45439355 transcription elongation factor A 1 isoform 2 [Homo ...    52   3e-06
gi|104526627 triadin [Homo sapiens]                                    52   4e-06
gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa...    50   1e-05
gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa...    50   1e-05
gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap...    50   1e-05
gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sap...    50   1e-05
gi|38505156 transcription elongation factor A protein 2 isoform ...    50   2e-05
gi|4507385 transcription elongation factor A protein 2 isoform a...    50   2e-05

>gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens]
          Length = 1189

 Score = 2392 bits (6198), Expect = 0.0
 Identities = 1189/1189 (100%), Positives = 1189/1189 (100%)

Query: 1    MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS 60
            MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
Sbjct: 1    MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS 60

Query: 61   LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE 120
            LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
Sbjct: 61   LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE 120

Query: 121  TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP 180
            TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
Sbjct: 121  TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP 180

Query: 181  LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG 240
            LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
Sbjct: 181  LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG 240

Query: 241  KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS 300
            KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
Sbjct: 241  KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS 300

Query: 301  EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS 360
            EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
Sbjct: 301  EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS 360

Query: 361  SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420
            SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
Sbjct: 361  SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420

Query: 421  HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK 480
            HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
Sbjct: 421  HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK 480

Query: 481  KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK 540
            KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
Sbjct: 481  KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK 540

Query: 541  AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL 600
            AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
Sbjct: 541  AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL 600

Query: 601  SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS 660
            SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
Sbjct: 601  SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS 660

Query: 661  AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR 720
            AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
Sbjct: 661  AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR 720

Query: 721  YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME 780
            YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
Sbjct: 721  YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME 780

Query: 781  SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT 840
            SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
Sbjct: 781  SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT 840

Query: 841  TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD 900
            TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
Sbjct: 841  TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD 900

Query: 901  EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT 960
            EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
Sbjct: 901  EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT 960

Query: 961  VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP 1020
            VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
Sbjct: 961  VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP 1020

Query: 1021 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF 1080
            DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
Sbjct: 1021 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF 1080

Query: 1081 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF 1140
            DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
Sbjct: 1081 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF 1140

Query: 1141 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR 1189
            SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR
Sbjct: 1141 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR 1189


>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
          Length = 2240

 Score = 2374 bits (6153), Expect = 0.0
 Identities = 1181/1181 (100%), Positives = 1181/1181 (100%)

Query: 1    MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS 60
            MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
Sbjct: 1    MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS 60

Query: 61   LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE 120
            LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
Sbjct: 61   LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE 120

Query: 121  TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP 180
            TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
Sbjct: 121  TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP 180

Query: 181  LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG 240
            LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
Sbjct: 181  LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG 240

Query: 241  KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS 300
            KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
Sbjct: 241  KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS 300

Query: 301  EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS 360
            EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
Sbjct: 301  EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS 360

Query: 361  SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420
            SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
Sbjct: 361  SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420

Query: 421  HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK 480
            HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
Sbjct: 421  HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK 480

Query: 481  KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK 540
            KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
Sbjct: 481  KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK 540

Query: 541  AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL 600
            AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
Sbjct: 541  AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL 600

Query: 601  SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS 660
            SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
Sbjct: 601  SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS 660

Query: 661  AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR 720
            AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
Sbjct: 661  AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR 720

Query: 721  YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME 780
            YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
Sbjct: 721  YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME 780

Query: 781  SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT 840
            SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
Sbjct: 781  SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT 840

Query: 841  TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD 900
            TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
Sbjct: 841  TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD 900

Query: 901  EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT 960
            EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
Sbjct: 901  EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT 960

Query: 961  VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP 1020
            VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
Sbjct: 961  VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP 1020

Query: 1021 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF 1080
            DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
Sbjct: 1021 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF 1080

Query: 1081 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF 1140
            DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
Sbjct: 1081 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF 1140

Query: 1141 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPG 1181
            SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPG
Sbjct: 1141 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPG 1181



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 41/170 (24%), Positives = 66/170 (38%), Gaps = 27/170 (15%)

Query: 508  DHNYNAVKPEKTAAPS-PSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPRNL 566
            D     ++PE+   P+ P +      E + S+    +  A+  T PPGS     P P   
Sbjct: 1212 DEKRTRLQPEEADVPAYPKVATVPQSEKKPSKYPLCSADAAVSTTPPGSPPPPPPLPEPP 1271

Query: 567  VPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGP---------- 616
            V K  S    AA +PA     +    T        A  S+ +SA++ A P          
Sbjct: 1272 VLKVLSSLKPAAPSPATAATTAAAAST--------AASSTASSASKTASPLEHILQTLFG 1323

Query: 617  APAAATAASKKFPGSAALVGAVRKPV------VPSVPMASPAPGRLGAMS 660
               +   ++++ PGS A  G  ++P       VP+ P+  P   + G  S
Sbjct: 1324 KKKSFDPSAREPPGSTA--GLPQEPKTTAEDGVPAPPLLDPIVQQFGQFS 1371



 Score = 31.6 bits (70), Expect = 4.7
 Identities = 42/183 (22%), Positives = 71/183 (38%), Gaps = 20/183 (10%)

Query: 868  APKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPE-----AVPEVASEPGLES--AS 920
            +P+   +   V  + +K   +S   D   +    + PE     A P+VA+ P  E   + 
Sbjct: 1184 SPRPNIILGLVICQKIKRPANSGELDKMDEKRTRLQPEEADVPAYPKVATVPQSEKKPSK 1243

Query: 921  HP--NVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTA 978
            +P  + D      PPG   P P PL    P P       V  V  S +    +P+++ T 
Sbjct: 1244 YPLCSADAAVSTTPPGSP-PPPPPL----PEPP------VLKVLSSLKPAAPSPATAATT 1292

Query: 979  VASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSES 1038
             A+A++   ST    ++   P   +   +  K     PS+   P   +  P    +T+E 
Sbjct: 1293 AAAASTAASSTASSASKTASPLEHILQTLFGKKKSFDPSAREPPGSTAGLPQEPKTTAED 1352

Query: 1039 RSP 1041
              P
Sbjct: 1353 GVP 1355


>gi|18375619 death inducer-obliterator 1 isoform a [Homo sapiens]
          Length = 562

 Score = 1082 bits (2798), Expect = 0.0
 Identities = 529/529 (100%), Positives = 529/529 (100%)

Query: 1   MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS 60
           MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
Sbjct: 1   MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS 60

Query: 61  LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE 120
           LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
Sbjct: 61  LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE 120

Query: 121 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP 180
           TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
Sbjct: 121 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP 180

Query: 181 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG 240
           LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
Sbjct: 181 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG 240

Query: 241 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS 300
           KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
Sbjct: 241 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS 300

Query: 301 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS 360
           EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
Sbjct: 301 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS 360

Query: 361 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420
           SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
Sbjct: 361 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420

Query: 421 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK 480
           HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
Sbjct: 421 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK 480

Query: 481 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYK 529
           KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYK
Sbjct: 481 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYK 529


>gi|18375617 death inducer-obliterator 1 isoform a [Homo sapiens]
          Length = 562

 Score = 1082 bits (2798), Expect = 0.0
 Identities = 529/529 (100%), Positives = 529/529 (100%)

Query: 1   MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS 60
           MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
Sbjct: 1   MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS 60

Query: 61  LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE 120
           LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
Sbjct: 61  LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE 120

Query: 121 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP 180
           TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
Sbjct: 121 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP 180

Query: 181 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG 240
           LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
Sbjct: 181 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG 240

Query: 241 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS 300
           KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
Sbjct: 241 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS 300

Query: 301 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS 360
           EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
Sbjct: 301 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS 360

Query: 361 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420
           SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
Sbjct: 361 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420

Query: 421 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK 480
           HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
Sbjct: 421 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK 480

Query: 481 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYK 529
           KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYK
Sbjct: 481 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYK 529


>gi|7662018 PHD finger protein 3 [Homo sapiens]
          Length = 2039

 Score =  199 bits (507), Expect = 1e-50
 Identities = 111/240 (46%), Positives = 147/240 (61%), Gaps = 34/240 (14%)

Query: 942  PLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKP 1001
            P++DLSP        V   V V+ +       S   A++S ++   S    E +Q+ PK 
Sbjct: 1128 PVDDLSP------KKVKVVVGVARKHSDNEAESIADALSSTSNILASEFFEEEKQESPKS 1181

Query: 1002 VLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFI 1061
                             SP PR    P  P     ES          FL+RL+ IWKGFI
Sbjct: 1182 TF---------------SPAPR----PEMPGTVEVEST---------FLARLNFIWKGFI 1213

Query: 1062 NMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIR 1121
            NM SVAKFVTKAYPVSG  +YL+EDLPD+I +GGRI+P+TVWDYV K+K+S +KE+C++R
Sbjct: 1214 NMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEKIKASGTKEICVVR 1273

Query: 1122 FHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPG 1181
            F P TEE++++Y  L++YFSSR R+GV ANN + VKD+YLIPL A D +P  L+PF+GPG
Sbjct: 1274 FTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGATDKIPHPLVPFDGPG 1333



 Score =  177 bits (449), Expect = 5e-44
 Identities = 109/283 (38%), Positives = 156/283 (55%), Gaps = 21/283 (7%)

Query: 660  SAAPSQPNS-QIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTD 718
            +A+ S+P++ QIRQ++R SLK+IL KR+ DS+ L + E +  K+A  IEKE+F+ F+ TD
Sbjct: 916  AASASKPSADQIRQSVRHSLKDILMKRLTDSN-LKVPEEKAAKVATKIEKELFSFFRDTD 974

Query: 719  NRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSV 778
             +YK+KYRS+MFNLKDPKN  LF +VL+ E++   L+R+ PEEL SKEL+ W+ R  R  
Sbjct: 975  AKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHT 1034

Query: 779  MESRTKLHNESKK---TAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKS------TAPL 829
            +E   K   E ++   T    +   ++E   P+ + E   E       KS      +   
Sbjct: 1035 IEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPAANKSLEKPEGSEKQ 1094

Query: 830  LDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDS 889
             +   SM KDTTSQHR HLFDLNCKIC G++    D+ +PKK K+   V +     KH  
Sbjct: 1095 KEEVDSMSKDTTSQHRQHLFDLNCKICIGRMAPPVDDLSPKKVKVVVGVAR-----KHSD 1149

Query: 890  SAPDPAPDSADEVMPEAVPEVASEPGLESASHPNVDRTYFPGP 932
            +  +   D+          E   E   ES        T+ P P
Sbjct: 1150 NEAESIADALSSTSNILASEFFEEEKQESPK-----STFSPAP 1187



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 67/291 (23%), Positives = 125/291 (42%), Gaps = 49/291 (16%)

Query: 264 YDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQ 323
           + P+     C++PH NRFM+ C RC++WFHGDCVG+S ++ + +    ++Y+C  C    
Sbjct: 714 WTPSKQCGFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCC--- 770

Query: 324 VQDETHSETAD------QQEAKWRPGDADGTDCTSIGTIEQKSSEDQGIKGRIEKAANPS 377
            +++  +E  D      Q   ++  GD    +C  +G + + ++ D+       K  + +
Sbjct: 771 AEEDKKTEILDPDTLENQATVEFHSGDKT-MECEKLG-LSKHTTNDR------TKYIDDT 822

Query: 378 GKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKP 437
            K K+KI +         +  G G       +S  C ++ I K   A ++ +      + 
Sbjct: 823 VKHKVKILK---------RESGEG------RNSSDCRDNEIKKWQLAPLRKMGQPVLPRR 867

Query: 438 KPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAA 497
             +EK +  P++ +   C    G K S        E K+  V+K V        L    A
Sbjct: 868 SSEEKSEKIPKESTTVTC---TGEKASKPGTHEKQEMKKKKVEKGV--------LNVHPA 916

Query: 498 CESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASK 548
             +S PS       + ++     +    L+ + T  + +  E+ AA  A+K
Sbjct: 917 ASASKPS------ADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATK 961


>gi|47271475 SPOC domain containing 1 [Homo sapiens]
          Length = 1216

 Score =  107 bits (267), Expect = 7e-23
 Identities = 98/361 (27%), Positives = 157/361 (43%), Gaps = 60/361 (16%)

Query: 596 KRPWLSATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVP--------SVP 647
           KRP +      G +  +   P+P+  TA            G +  P  P          P
Sbjct: 523 KRPMVQ-----GPAGCQVFQPSPSGGTAGDP---------GGLSDPFYPPRSGSLALGDP 568

Query: 648 MASPAPGRLGAMSAA----PSQPNSQ-------------IRQNIRRSLKEILWKRVNDSD 690
            + PA  + G M A     P QP                +R  + RS++E+LW R+ +  
Sbjct: 569 SSDPACSQSGPMEAEEDSLPEQPEDSAQLQQEKPSLYIGVRGTVVRSMQEVLWTRLRELP 628

Query: 691 DLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRVLREEIS 750
           D +++E  V  IA  IE  +++L Q T+ RYK+KYRS++FNL+DP+N  LF +V+  +++
Sbjct: 629 DPVLSEEVVEGIAAGIEAALWDLTQGTNGRYKTKYRSLLFNLRDPRNLDLFLKVVHGDVT 688

Query: 751 LAKLVRLKPEELVSKELSTWK---ERPARSVMESRTK---LHNESKKTAPRQEAIP-DLE 803
              LVR+   +L  +EL+ W+   E+   +++E + K       SK T   +  I  D++
Sbjct: 689 PYDLVRMSSMQLAPQELARWRDQEEKRGLNIIEQQQKEPCRLPASKMTHKGEVEIQRDMD 748

Query: 804 DSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSA 863
            +  + D    Q      P+    P+        +DTT QH  H  D NC IC    PS 
Sbjct: 749 QTLTLEDLVGPQMFMDCSPQ--ALPIAS------EDTTGQHDHHFLDPNCHICKDWEPSN 800

Query: 864 EDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPD--SADEVMPEAVPEVASEPGLESASH 921
           E   + +  K       +++  K  S  P PAP+     E+ P    +     GL   + 
Sbjct: 801 ELLGSFEAAKSCG----DNIFQKALSQTPMPAPEMPKTRELSPTEPQDRVPPSGLHVPAA 856

Query: 922 P 922
           P
Sbjct: 857 P 857



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 53/179 (29%), Positives = 86/179 (48%), Gaps = 16/179 (8%)

Query: 1010 KSILAKPSSSPDPRYLSVPPSPNISTSE--SRSPPEG-----DTTLFLSRLSTIWKGFIN 1062
            K++   P  +P+     +P +  +S +E   R PP G       T  L  L   W+G ++
Sbjct: 819  KALSQTPMPAPE-----MPKTRELSPTEPQDRVPPSGLHVPAAPTKALPCLPP-WEGVLD 872

Query: 1063 MQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRF 1122
            M S+ +F  +A  VSG    L + LP  I   G I    VWD +  +  + +K++C++R 
Sbjct: 873  MFSIKRFRARAQLVSGHSCRLVQALPTVIRSAGCIPSNIVWDLLASICPAKAKDVCVVRL 932

Query: 1123 HPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPG 1181
             P    +      LYSY + R R G+ +  +     + L+PL A  P+P++L P  GPG
Sbjct: 933  CPHGARDTQNCRLLYSYLNDRQRHGLASVEH---MGMVLLPLPAFQPLPTRLRPLGGPG 988


>gi|90093355 jumonji C domain containing histone demethylase 1
           homolog D [Homo sapiens]
          Length = 941

 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 43/121 (35%), Positives = 58/121 (47%), Gaps = 21/121 (17%)

Query: 240 GKAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHN-NRFMICCDRCEEWFHGDCVG 298
           G AA  +    PG    P P      P  +YC+CRQP++ NRFMI CD C++WFHG CVG
Sbjct: 15  GAAAAAVSVAAPGRASAPPP------PPPVYCVCRQPYDVNRFMIECDICKDWFHGSCVG 68

Query: 299 ISEARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGD----ADGTDCTSIG 354
           + E     ++     Y CPNC +L      H  +  ++   W   D     DG+     G
Sbjct: 69  VEEHHAVDIDL----YHCPNCAVL------HGSSLMKKRRNWHRHDYTEIDDGSKPVQAG 118

Query: 355 T 355
           T
Sbjct: 119 T 119


>gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]
          Length = 660

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 31/75 (41%), Positives = 41/75 (54%), Gaps = 5/75 (6%)

Query: 245 DIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARG 304
           D  D EP D G    + E  +   +YCICR+P  N FMI CD C EWFHGDC+ I+E   
Sbjct: 4   DGSDPEPPDAGEDS-KSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEKMA 62

Query: 305 RLLERNGEDYICPNC 319
           + +     ++ C  C
Sbjct: 63  KAI----REWYCREC 73



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 17/28 (60%), Positives = 21/28 (75%)

Query: 396 KCIGPGCCHVAQPDSVYCSNDCILKHAA 423
           +C+GPGC   AQP S YCS+DC +K AA
Sbjct: 378 QCLGPGCVRPAQPSSKYCSDDCGMKLAA 405


>gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]
          Length = 656

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 31/75 (41%), Positives = 41/75 (54%), Gaps = 5/75 (6%)

Query: 245 DIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARG 304
           D  D EP D G    + E  +   +YCICR+P  N FMI CD C EWFHGDC+ I+E   
Sbjct: 4   DGSDPEPPDAGEDS-KSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEKMA 62

Query: 305 RLLERNGEDYICPNC 319
           + +     ++ C  C
Sbjct: 63  KAI----REWYCREC 73



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 17/28 (60%), Positives = 21/28 (75%)

Query: 396 KCIGPGCCHVAQPDSVYCSNDCILKHAA 423
           +C+GPGC   AQP S YCS+DC +K AA
Sbjct: 374 QCLGPGCVRPAQPSSKYCSDDCGMKLAA 401


>gi|117190342 PHD finger protein 2 [Homo sapiens]
          Length = 1096

 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 31/81 (38%), Positives = 47/81 (58%), Gaps = 14/81 (17%)

Query: 269 LYCICRQPHN-NRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDE 327
           +YC+CR P++  RFMI CD C++WFHG CVG+ E     +    + Y CPNC      ++
Sbjct: 6   VYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDI----DIYHCPNC------EK 55

Query: 328 THSETADQQEAKWR---PGDA 345
           TH ++  +++  W    PG A
Sbjct: 56  THGKSTLKKKRTWHKHGPGQA 76


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 126/611 (20%), Positives = 228/611 (37%), Gaps = 74/611 (12%)

Query: 323  QVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKSSEDQGIKGRIEKAANPSGKKKL 382
            QV +E   E  +++EAK    + +G +       E +  E++      E+AA+P  + K 
Sbjct: 465  QVTEEVTEE--EEKEAK----EEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKS 518

Query: 383  KIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEK 442
             + +   EA   ++   P       P  V        K  +   +   S  E K   KE+
Sbjct: 519  PVKE---EAKSPAEAKSPEKEEAKSPAEVKSPE----KAKSPAKEEAKSPPEAKSPEKEE 571

Query: 443  MKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESST 502
             K   E  S  K  + A  +  S  +  +PEK ++ VK+    PA +++  KE   E+ +
Sbjct: 572  AKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE---EAKS 628

Query: 503  PSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKA-----AAMAASKKTAPPGSAV 557
            P+        A  P K  A SP       KE+ +S EKA     A   + +K   P  A 
Sbjct: 629  PAEVKSPE-KAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAE 687

Query: 558  GKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIP-----KRPWLSATPSSGASAAR 612
             K P       K+ + +   A +P  ++  S  K   P     K P  + +P    + + 
Sbjct: 688  AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSP 747

Query: 613  QAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQ 672
            +   +P  A     K P +        +      P  + +P +    S  P +  S +++
Sbjct: 748  EKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKS--PEKAKSPLKE 805

Query: 673  NIRRSLKEILWKRVNDS---DDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIM 729
            + +   KEI  K    S   ++    E +V +     E+E       T+ +  SK     
Sbjct: 806  DAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKE--- 862

Query: 730  FNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNES 789
               + PK +                    P+  V ++     E+P  S +E++ +   + 
Sbjct: 863  ---EAPKKEA-------------------PKPKVEEKKEPAVEKPKESKVEAKKEEAEDK 900

Query: 790  KKT-APRQEA---IPDLEDSPPVSDSE-EQQESARAVPEKSTAPLLDVFSSMLKDTTSQH 844
            KK   P +EA   +   ED+ P   +E  ++E   A  ++ + P     ++  K  T + 
Sbjct: 901  KKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEE 960

Query: 845  RAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMP 904
            +A            + P  + +   K ++   ++ KE  K K + +    + D  D   P
Sbjct: 961  KA------------KKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPP 1008

Query: 905  EAVPEVASEPG 915
            E   E  +  G
Sbjct: 1009 EKATEDKAAKG 1019



 Score = 37.4 bits (85), Expect = 0.086
 Identities = 87/499 (17%), Positives = 166/499 (33%), Gaps = 89/499 (17%)

Query: 106 DAETASEGSVESASETRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQ 165
           + +T      E  +E            +E     E+ +GG++   +  ++      KE +
Sbjct: 458 EEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAK 517

Query: 166 NRLRRKR----EQEPTERPLKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQE--- 218
           + ++ +     E +  E+      + ++   + + PA+    EA    E   P K+E   
Sbjct: 518 SPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAK---EEAKSPPEAKSPEKEEAKS 574

Query: 219 ------PENDQGVVSQAGKDDRESKLEGKAAQDIKDE--EPGDLGRPKPECEGYDPNALY 270
                 PE  +    +  K   E+K   KA   +K+E   P +   P  E          
Sbjct: 575 PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE---------- 624

Query: 271 CICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDETHS 330
                                         EA+     ++ E    P  T  + +    +
Sbjct: 625 ------------------------------EAKSPAEVKSPEKAKSP--TKEEAKSPEKA 652

Query: 331 ETADQQEAKWRPGDADGTDCTSIGTIEQKSSEDQGIKGRIEKAANPSGKKKLKIFQPVIE 390
           ++ +++EAK  P  A          ++ ++   +  K  ++  A    K K  + +   E
Sbjct: 653 KSPEKEEAK-SPEKAK-------SPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKE---E 701

Query: 391 APGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMKMKPEKP 450
           A    K   P       P+         +K  A T +   S  +++ K  EK K   +  
Sbjct: 702 AKSPEKAKSPVKEEAKSPEKAKSP----VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAK 757

Query: 451 SLPKCGAQAGIKISSVHKRPA---PEKKETTVKKAVVVPARSEALGKEAACESSTPSWAS 507
           +L     +A        + PA   PEK ++ VK+ V  P ++++  KE   ++  P    
Sbjct: 758 TLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKE---DAKAPEKEI 814

Query: 508 DHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPRNLV 567
                   P K       +  K   +    E+  A     +K         K+ AP+  V
Sbjct: 815 PKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKV 874

Query: 568 PKKSSFANVAAATPAIKKP 586
            +K          PA++KP
Sbjct: 875 EEKKE--------PAVEKP 885



 Score = 37.4 bits (85), Expect = 0.086
 Identities = 34/168 (20%), Positives = 70/168 (41%), Gaps = 11/168 (6%)

Query: 104 ATDAETASEGSVESASETRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKE 163
           A + E   +  V+S  +    PQ        + A  EK       ++  DS  +    KE
Sbjct: 809 APEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKE 868

Query: 164 LQN-RLRRKRE---QEPTERPLKGIQSRLRKKRR-----EEGPAETVGSEASDTVEGVLP 214
               ++  K+E   ++P E  ++  +     K++     +E PA+    E +   E    
Sbjct: 869 APKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEV 928

Query: 215 SKQEPENDQGVVSQAGKDDRESKLEGKAAQDIKDEEPGDLGRPKPECE 262
           +K+EP++ +        + +E+  E K  ++ K ++P +  +PK E +
Sbjct: 929 AKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEE--KPKTEAK 974



 Score = 31.6 bits (70), Expect = 4.7
 Identities = 41/208 (19%), Positives = 77/208 (37%), Gaps = 16/208 (7%)

Query: 750 SLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLEDSPPVS 809
           S++  +++K EE +     + KE     ++E +T+    +++    +E     E+     
Sbjct: 431 SVSTHIKVKSEEKIKVVEKSEKETV---IVEEQTEETQVTEEVTEEEEKEAKEEEGKEEE 487

Query: 810 DSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAEDEPAP 869
             EE  E A    E++ +P  +  +S  K+  S  +             + P+    P  
Sbjct: 488 GGEE--EEAEGGEEETKSPPAEEAASPEKEAKSPVKEE----------AKSPAEAKSPEK 535

Query: 870 KKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNVDRTYF 929
           ++ K  A VK  + K+K  +     +P  A     E     A     E A  P  +    
Sbjct: 536 EEAKSPAEVKSPE-KAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS 594

Query: 930 PGPPGDGHPEPSPLEDLSPCPASCGSGV 957
           P          SP+++ +  PA   S V
Sbjct: 595 PAEAKSPEKAKSPVKEEAKSPAEAKSPV 622


>gi|32698700 PHD finger protein 8 [Homo sapiens]
          Length = 1024

 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 26/55 (47%), Positives = 37/55 (67%), Gaps = 5/55 (9%)

Query: 269 LYCICRQPHN-NRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTIL 322
           +YC+CR P++  RFMI CD C++WFHG CVG+ E +   ++     Y CPNC +L
Sbjct: 6   VYCLCRLPYDVTRFMIECDMCQDWFHGSCVGVEEEKAADIDL----YHCPNCEVL 56


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
            [Homo sapiens]
          Length = 2903

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 24/52 (46%), Positives = 37/52 (71%), Gaps = 5/52 (9%)

Query: 269  LYCICRQPHN-NRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNC 319
            LYCIC+ P++ ++F I CDRC+ W+HG CVGI ++   L+    ++Y+CP C
Sbjct: 2725 LYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELI----DEYVCPQC 2772


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
            [Homo sapiens]
          Length = 2920

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 24/52 (46%), Positives = 37/52 (71%), Gaps = 5/52 (9%)

Query: 269  LYCICRQPHN-NRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNC 319
            LYCIC+ P++ ++F I CDRC+ W+HG CVGI ++   L+    ++Y+CP C
Sbjct: 2742 LYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELI----DEYVCPQC 2789


>gi|41350335 transcription elongation factor A (SII), 3 [Homo
           sapiens]
          Length = 348

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 60/240 (25%), Positives = 91/240 (37%), Gaps = 21/240 (8%)

Query: 553 PGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAAR 612
           PG   G++   R    KK      +   P     P   K   PK    S    S AS++ 
Sbjct: 82  PGPPKGEKGEEREKAKKKEKGLECSDWKPEAGLSPPRKKREDPKTRRDSVDSKSSASSSP 141

Query: 613 QAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQ 672
           +      + ++ SK              P  PS P+         A S     P      
Sbjct: 142 KRPSVERSNSSKSK-----------AESPKTPSSPLTPTF-----ASSMCLLAPCYLTGD 185

Query: 673 NIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNL 732
           ++R    E+L   +   DD         K+A  IE  ++   + TD +Y+++ RS + NL
Sbjct: 186 SVRDKCVEMLSAALKADDDYKDYGVNCDKMASEIEDHIYQELKSTDMKYRNRVRSRISNL 245

Query: 733 KDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKT 792
           KDP+N GL   VL   IS   + ++  EE+ S EL     R  R+ M       ++  KT
Sbjct: 246 KDPRNPGLRRNVLSGAISAGLIAKMTAEEMASDEL-----RELRNAMTQEAIREHQMAKT 300


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 118/554 (21%), Positives = 194/554 (35%), Gaps = 101/554 (18%)

Query: 439   PKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTV--KKAVVVPARSEALGKEA 496
             PKE +  K    + PK      +K+    K   PEKK      KK  V P +   + K A
Sbjct: 10585 PKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVA 10644

Query: 497   ACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSA 556
               E   P            P K  +P P + ++  +E    E  A  +   +  APP   
Sbjct: 10645 VPEKKVPE---------AIPPKPESPPPEV-FEEPEEVALEEPPAEVVEEPEPAAPPQVT 10694

Query: 557   VGKQPAPRNLVPKKSSFANVA-------AATPAIKK---PPSGFKGTIPKRPWLSATPSS 606
             V     P+  VP+K + A VA          P + K   P       +PK+P   A P+ 
Sbjct: 10695 V----PPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKP--EAPPAK 10748

Query: 607   GASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQP 666
                  ++  P    A     + P  A +    +KPV+   P A P P R      A S P
Sbjct: 10749 VPEVPKEVVPEKKVAVPKKPEVP-PAKVPEVPKKPVLEEKP-AVPVPER------AESPP 10800

Query: 667   NSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYR 726
                  +           + +   +++   E +   +A   E E      V       + +
Sbjct: 10801 PEVYEEP----------EEIAPEEEIAPEEEKPVPVAEEEEPE------VPPPAVPEEPK 10844

Query: 727   SIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPA--------RSV 778
              I+   K P        + + E    K    +PE+++ K     K RP           V
Sbjct: 10845 KIIPEKKVPV-------IKKPEAPPPK--EPEPEKVIEKP--KLKPRPPPPPPAPPKEDV 10893

Query: 779   MESRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDV-FSSML 837
              E   +L    KK  P +  +P+  +  P+     +++  + +PE+   P  +V   S+L
Sbjct: 10894 KEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVL 10953

Query: 838   KDTTSQHRAHLFDLNCKICTGQVPSAEDEPAPK-------------KQKLSASVKKEDLK 884
             +    +    +     K+   + P+  + P PK             ++K+    K  ++K
Sbjct: 10954 RKRPEEEEPKVEPK--KLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIK 11011

Query: 885   SKHDSSAPDPAPDSADEVMPEAVPEVASEP------------GLESASHPNVDRTYFPGP 932
                   AP+P P    EV     P V  EP            G ++ +    +    P  
Sbjct: 11012 PAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKG 11071

Query: 933   PGDGHPE--PSPLE 944
             P  G P+  PSP+E
Sbjct: 11072 PIKGVPKKTPSPIE 11085



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 109/504 (21%), Positives = 182/504 (36%), Gaps = 68/504 (13%)

Query: 433   KEQKPKPKEKMKMKP------EKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVP 486
             KEQ  +P  K+ MKP      EK  +P+      +++  V K   PE  E   ++ VV  
Sbjct: 9860  KEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPE--EVAFEEEVVTH 9917

Query: 487   ARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAA 546
                  + +E         + ++     V P K     P +  K   E     EK      
Sbjct: 9918  VEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKV----PEVPRKPVPE-----EKKPVPVP 9968

Query: 547   SKKTAPPGSA--VGKQPAPRN--LVPKKSSFANVAAATPAI-KKPPSGFKGTIPKRPWLS 601
              KK APP     V K+P  +   L+PKK       A  P + KKP    K  +P    + 
Sbjct: 9969  KKKEAPPAKVPEVPKKPEEKVPVLIPKKEK--PPPAKVPEVPKKPVPEEKVPVPVPKKVE 10026

Query: 602   ATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSA 661
             A P+      ++  P       A KK     A V  V K ++P     +P P ++ A   
Sbjct: 10027 APPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEA--P 10084

Query: 662   APSQPNSQIRQNIRRSL---KEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTD 718
              P  P  +    +  +L   +E+L++     ++ ++ E E     L  E+E+        
Sbjct: 10085 PPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEE---VLPEEEEVL------- 10134

Query: 719   NRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSV 778
                  +   +    + P  +     V  EE  + +     PEE V  E+      PA   
Sbjct: 10135 ---PEEEEVLPEEEEIPPEE---EEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPA--- 10185

Query: 779   MESRTKLHNESKKTAPRQEAIPDLEDSPPVSDSE---EQQESARAVPEKSTAPLLDVFSS 835
                   +    KK   ++  IP  E++PP    E   + +E    +P++     ++V   
Sbjct: 10186 -----PVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEE 10240

Query: 836   MLKDTTSQ----HRAHLFDLNCKICTGQVP-----SAEDEPAPKKQKLSASVKKEDLKSK 886
               ++  S+          +   ++   +VP     +  + P P  +K+ A   K   K  
Sbjct: 10241 PEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIP 10300

Query: 887   HDSSAPDPAPDSADEVMPEAVPEV 910
              +     P P    E  P  VPEV
Sbjct: 10301 EEKV---PVPVQKKEAPPAKVPEV 10321



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 135/650 (20%), Positives = 226/650 (34%), Gaps = 147/650 (22%)

Query: 434   EQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALG 493
             E++  P E+  +  E+  +P+      +K       P PE K+   +K VV+P + EA  
Sbjct: 10150 EEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEA-- 10207

Query: 494   KEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPP 553
                A     P    +      K E+     P  + +  +E+  SEE+           PP
Sbjct: 10208 -PPAKVPEVPKKVEEKRIILPKEEEVL---PVEVTEEPEEEPISEEEI-------PEEPP 10256

Query: 554   GSAVGKQPAPRNLVPKKSSFANVAAATPAIKK---PPSGFKGTIPKRPWLSATPSSGASA 610
                  ++ AP   VP+    A   A TP  KK   PP+     IP+              
Sbjct: 10257 SIEEVEEVAPPR-VPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEE-------KVPVPV 10308

Query: 611   ARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGR--LGAMSAAPSQPNS 668
              ++  P PA      KK P         +K +VP      PA GR  L    +   +   
Sbjct: 10309 QKKEAP-PAKVPEVPKKVP--------EKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEV 10359

Query: 669   QIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQ---VTDNRYKSKY 725
              +++ +   + E   + + + ++    E    +   H  +E   L Q     ++R +  +
Sbjct: 10360 VVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVH 10419

Query: 726   RSI-MFNLKD----------PKNQGLFHRVLREEISLAKLV-RLKPEELVSKELSTWKER 773
             R I +F  ++          PK   +  +++  +    K+V R +P   V        E 
Sbjct: 10420 RVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKV-------PEV 10472

Query: 774   PARSVMESRTKLHNESK-------KTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKST 826
             P + V+E + ++  E +       +  P +E +P  E   PV  +++ +     VPE   
Sbjct: 10473 PKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVP--EKKVPVPPAKKPEAPPPKVPE--- 10527

Query: 827   APLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSAS----VKKED 882
             AP         K+   + +  +                  P PKK ++  +    V K  
Sbjct: 10528 AP---------KEVVPEKKVPV------------------PPPKKPEVPPTKVPEVPKAA 10560

Query: 883   LKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESA--SHPNVDRTYFPGPPGDGHPEP 940
             +  K    A  P P+S    +PEA  EV  E  + +A    P V     P  P +  PE 
Sbjct: 10561 VPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEK 10620

Query: 941   SPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPK 1000
                    P P                 P   P    T V                 +VPK
Sbjct: 10621 K-----VPVP-----------------PPKKPEVPPTKV----------------PEVPK 10642

Query: 1001  PVLTSVMVPKSILAKPSSSPDPRY-------LSVPPSPNISTSESRSPPE 1043
               +    VP++I  KP S P   +       L  PP+  +   E  +PP+
Sbjct: 10643 VAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQ 10692



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 100/495 (20%), Positives = 180/495 (36%), Gaps = 96/495 (19%)

Query: 435  QKPKPKEKMKMKPEKPS--------LPKCGAQAGIKISSVHKRPAPEKKE--TTVKKAVV 484
            ++ +P  K+   PEKP+        +PK       K+  V K+P PE+K+     KK   
Sbjct: 9280 KRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPA 9339

Query: 485  VPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAM 544
             P +   + K+   E   P          V  +K A P+        ++   +EEK   +
Sbjct: 9340 APPKVPEVPKKPVPEEKIPV--------PVAKKKEAPPAK---VPEVQKGVVTEEKITIV 9388

Query: 545  AASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATP 604
               +++ PP  AV +       +PKK          P  +KP    +  +P  P + A P
Sbjct: 9389 TQREESPPP--AVPE-------IPKKK--------VPEERKPVPRKEEEVPPPPKVPALP 9431

Query: 605  SSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPS 664
                   + A P P A  A   +   S   V    K  V    ++   P R+        
Sbjct: 9432 KKPVPEEKVAVPVPVAKKAPPPRAEVSKKTV-VEEKRFVAEEKLSFAVPQRV-------- 9482

Query: 665  QPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVG-KIALHIEKEMFNLFQVTDNRYKS 723
                           E+    V+  ++   +E E G  I+++ E+E     +     Y+ 
Sbjct: 9483 ---------------EVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEV 9527

Query: 724  KYRSIMFNLKDPKNQGLFHRVLREEIS-LAKLVRLKPEELVSKE----------LSTWKE 772
                    +++P+       V+ E++  ++K V  +P E+  ++           +  +E
Sbjct: 9528 --------MEEPEEY-----VVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEE 9574

Query: 773  RPARSVMESRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAP-LLD 831
             P   V E+  K+  E K  AP    +P  E  PP    EE +   + VPEK   P ++ 
Sbjct: 9575 PPPAKVPEAPKKIVPEKKVPAP----VPKKEKVPPPKVPEEPK---KPVPEKKVPPKVIK 9627

Query: 832  VFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKE-DLKSKHDSS 890
            +   +    T +H     +    +   +  +      P++ K +   +K   LK K +  
Sbjct: 9628 MEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEE 9687

Query: 891  APDPAPDSADEVMPE 905
             P    +    V+ E
Sbjct: 9688 PPAKVTEFRKRVVKE 9702



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 54/220 (24%), Positives = 80/220 (36%), Gaps = 35/220 (15%)

Query: 433   KEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEAL 492
             KE  P+ K  + + P+KP  P        K+  V K   PEKK    KK  V PA+   +
Sbjct: 10726 KEVVPEKKVPLVV-PKKPEAPPA------KVPEVPKEVVPEKKVAVPKKPEVPPAKVPEV 10778

Query: 493   GKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYK-----STKEDRRSEEKAAAMAAS 547
              K+   E                PE+  +P P +  +       +E    EEK   +A  
Sbjct: 10779 PKKPVLEEKPA---------VPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEE 10829

Query: 548   KKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSG 607
             ++   P  AV ++  P+ ++P+K          P IKKP    +   PK P         
Sbjct: 10830 EEPEVPPPAVPEE--PKKIIPEKK--------VPVIKKP----EAPPPKEPEPEKVIEKP 10875

Query: 608   ASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVP 647
                 R   P PA      K+       +   + P  P VP
Sbjct: 10876 KLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVP 10915



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 139/677 (20%), Positives = 220/677 (32%), Gaps = 112/677 (16%)

Query: 448   EKPSLPKCGAQAGIKISSVHKRPA-------PEKKETTVKKAVVVPARSEA-----LGKE 495
             EKP  P  G +   KI    K P        P  K   V K +VV  +        +   
Sbjct: 10434 EKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPT 10493

Query: 496   AACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPG- 554
                E   P          V P K     P  + ++ KE    E+K       K   PP  
Sbjct: 10494 KVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVV-PEKKVPVPPPKKPEVPPTK 10552

Query: 555   ------SAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGA 608
                   +AV ++  P  + PK  S        P    P        PK+P    TP    
Sbjct: 10553 VPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKP--EVTPVKVP 10610

Query: 609   SAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNS 668
              A ++  P         KK       V  V K  VP   +    P +       P  P  
Sbjct: 10611 EAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPK-------PESPPP 10663

Query: 669   QIRQNIRR-SLKEILWKRVNDSDDLIMTENEV------------GKIALHIEKEMFNLFQ 715
             ++ +     +L+E   + V + +     +  V              +A   E     + +
Sbjct: 10664 EVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPE 10723

Query: 716   VTDNRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKL-VRLKPEELVSK-----ELST 769
             V       K   ++   K          V +E +   K+ V  KPE   +K     +   
Sbjct: 10724 VPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPV 10783

Query: 770   WKERPARSVMESRT----KLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPE-- 823
              +E+PA  V E       +++ E ++ AP +E  P+ E   PV++ EE +    AVPE  
Sbjct: 10784 LEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEP 10843

Query: 824   --------------------KSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSA 863
                                 K   P   +    LK             + K    Q+ + 
Sbjct: 10844 KKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAI 10903

Query: 864   EDEPAPKKQKLSASVKKEDLK-----SKHDSSAPDPAPDSADEVMPEAV----PEVASEP 914
               +  P+K ++   V+   LK      K     P+  P+  +EV+ ++V    PE   EP
Sbjct: 10904 PKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPE-EEEP 10962

Query: 915   GLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGR---DPRTA 971
              +E      V +   P P     P P P+E++           V TVT   R   +P   
Sbjct: 10963 KVEPKKLEKVKKPAVPEP-----PPPKPVEEVE----------VPTVTKRERKIPEPTKV 11007

Query: 972   PSSSCTAVASAASRPDSTHMVEAR-------QDVPKPVLTSVMVPKSILAKPSSSPDPRY 1024
             P     A+   A  P      E +       +  P P+   V VP  ++ K + +  P+ 
Sbjct: 11008 PEIK-PAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVP--VVGKKAEAKAPKE 11064

Query: 1025  LSVPPSPNISTSESRSP 1041
              +  P   I     ++P
Sbjct: 11065 EAAKPKGPIKGVPKKTP 11081



 Score = 37.7 bits (86), Expect = 0.066
 Identities = 70/302 (23%), Positives = 105/302 (34%), Gaps = 57/302 (18%)

Query: 783   TKLHNESKKTAPRQ---EAIPDLEDSPPVSDSEEQQE------SARAVPEKSTAPLLDVF 833
             TK+    K   P +   EAIP   +SPP    EE +E       A  V E   A    V 
Sbjct: 10635 TKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVT 10694

Query: 834   SSMLKDTTSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPD 893
                 K    +    +     ++   +VP    E  P+K+      KK +       + P 
Sbjct: 10695 VPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPE-------APPA 10747

Query: 894   PAPDSADEVMPE--------------AVPEVASEPGL-ESASHPNVDRTYFPGPPGDGHP 938
               P+   EV+PE               VPEV  +P L E  + P  +R     PP + + 
Sbjct: 10748 KVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERA--ESPPPEVYE 10805

Query: 939   EPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAASR--PDSTHMVEARQ 996
             EP   E+++P                  +P   P     AV     +  P+    V  + 
Sbjct: 10806 EP---EEIAPEEEIAPEEEKPVPVAEEEEPEVPP----PAVPEEPKKIIPEKKVPVIKKP 10858

Query: 997   DVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTI 1056
             + P P       P+ ++ KP   P P     PP P        +PP+ D    + +L  I
Sbjct: 10859 EAPPP---KEPEPEKVIEKPKLKPRP-----PPPP-------PAPPKEDVKEKIFQLKAI 10903

Query: 1057  WK 1058
              K
Sbjct: 10904 PK 10905



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 38/153 (24%), Positives = 61/153 (39%), Gaps = 14/153 (9%)

Query: 433  KEQKPKPKEKMKMKPEKPSLPKCGA-QAGIKISSVHKRPAPEKKETTVKKAVVVPARSEA 491
            K+  P PK++    P+ P +PK    +  I +    K+ AP  K   V+K VV   +   
Sbjct: 9328 KKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITI 9387

Query: 492  LGKEAACESSTPSWASDHNYNAVKPEKTAAPS-------PSLLYKSTKEDRRSEEKAAAM 544
            + +    E S P    +     V  E+   P        P  +    K+    E+ A  +
Sbjct: 9388 VTQR---EESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPV 9444

Query: 545  AASKKTAPPGSAVGKQPA---PRNLVPKKSSFA 574
              +KK  PP + V K+      R +  +K SFA
Sbjct: 9445 PVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFA 9477



 Score = 33.9 bits (76), Expect = 0.95
 Identities = 34/137 (24%), Positives = 58/137 (42%), Gaps = 17/137 (12%)

Query: 433   KEQKPKPKEKMKMKPEKPSL-----PKCGAQAGIKISSVHKRPAPE-KKETTVKKAVVVP 486
             +E++PK + K   K +KP++     PK   +  +   +  +R  PE  K   +K A+ +P
Sbjct: 10958 EEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLP 11017

Query: 487   ARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAA 546
             A       EA  ++  P          V+PE T   +P  +       +++E KA    A
Sbjct: 11018 APEPKPKPEAEVKTIKPP--------PVEPEPTPIAAPVTV---PVVGKKAEAKAPKEEA 11066

Query: 547   SKKTAPPGSAVGKQPAP 563
             +K   P      K P+P
Sbjct: 11067 AKPKGPIKGVPKKTPSP 11083



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 34/139 (24%), Positives = 61/139 (43%), Gaps = 18/139 (12%)

Query: 434  EQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKK--ETTVKKAVVVPARSEA 491
            E   + ++K+ +KP+ P+  K       K+    K+  PEKK      KK  V P +   
Sbjct: 9553 EVTERQEKKIVLKPKIPA--KIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPE 9610

Query: 492  LGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTA 551
              K+   E   P           K  K   P P+ +  + +  + ++E+   +A +KK A
Sbjct: 9611 EPKKPVPEKKVPP----------KVIKMEEPLPAKV--TERHMQITQEEKVLVAVTKKEA 9658

Query: 552  PPGSAVGKQPAPRNLVPKK 570
            PP + V ++  P+  VP++
Sbjct: 9659 PPKARVPEE--PKRAVPEE 9675



 Score = 32.0 bits (71), Expect = 3.6
 Identities = 47/211 (22%), Positives = 84/211 (39%), Gaps = 25/211 (11%)

Query: 746   REEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAI-PDLED 804
             RE + +   +  + E L  +E+      P   V+    ++  E ++  P +E + P+ E+
Sbjct: 10092 REPVPVPVALPQEEEVLFEEEIV-----PEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEE 10146

Query: 805   SPPVSDSEEQQESARAVPEKST-APLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQV--P 861
              PP  + EE       VPE+    P  +V   +         A + ++  K+   +V  P
Sbjct: 10147 IPP--EEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVP--APVPEIKKKVTEKKVVIP 10202

Query: 862   SAEDEP------APKK--QKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASE 913
               E+ P       PKK  +K     K+E++     +  P+  P S +E+ PE  P +   
Sbjct: 10203 KKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEI-PEEPPSIEE- 10260

Query: 914   PGLESASHPNVDRTYFPGPPGDGHPEPSPLE 944
               +E  + P V        P    P P  +E
Sbjct: 10261 --VEEVAPPRVPEVIKKAVPEAPTPVPKKVE 10289


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 97/517 (18%), Positives = 161/517 (31%), Gaps = 34/517 (6%)

Query: 546  ASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPS 605
            +SKK  PP  A     +     PK     N       I+      + ++ +    S++ S
Sbjct: 74   SSKKAPPPSGASQTIKSTTKRSPKPP---NKKKTKKVIESEEITEEHSVSENQESSSSSS 130

Query: 606  SGASAAR----QAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSA 661
            S +S++     ++    AA     KK           +K   P  P+   A   L     
Sbjct: 131  SSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDF 190

Query: 662  APSQPNSQIRQN--IRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDN 719
              + P++   Q+  +  S K    K +N    L    +   + +L + KE     + T  
Sbjct: 191  KVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTT 250

Query: 720  RYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVM 779
              K             K      +   ++++    V  KP    + +  T  + PA +  
Sbjct: 251  TNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP----TPKAETTTKGPALTTP 306

Query: 780  ESRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKD 839
            +  T    +   +   +E  P    S P +  E    + ++ P     P           
Sbjct: 307  KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 366

Query: 840  TTSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSA 899
            T  +             T   P+   EPAP   K  A       K    ++  +P P + 
Sbjct: 367  TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP---KEPAPTTPKEPTPTTP 423

Query: 900  DEVMP---EAVPEVASEPGLESASHPNVDRTYFPGPPGDGHP------EPSPLEDLSPCP 950
             E  P   E  P    EP   +   P       P P     P      EPSP     P P
Sbjct: 424  KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 483

Query: 951  ASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPK------PVLT 1004
             +  S   TT   +    ++AP++      +    P  T   E     PK      P   
Sbjct: 484  TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 543

Query: 1005 SVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSP 1041
            +   PK      +  P P   + P  P  +T +  +P
Sbjct: 544  APTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAP 577



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 68/270 (25%), Positives = 98/270 (36%), Gaps = 33/270 (12%)

Query: 425 TMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVV 484
           T +  ++ K+     KEK     E  S+ K  A+     S V  +P P+ + TT   A+ 
Sbjct: 245 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT 304

Query: 485 VPAR-SEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAA 543
            P   +    KE A  S+TP    +     +K   T    P+    +T +   +  K  A
Sbjct: 305 TPKEPTPTTPKEPA--STTP---KEPTPTTIKSAPTTPKEPA---PTTTKSAPTTPKEPA 356

Query: 544 MAASKKTAP-----PGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKP----PSGFKGTI 594
              +K+ AP     P     K+PAP       ++    A  TP  KKP    P     T 
Sbjct: 357 PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP--KKPAPTTPKEPAPTT 414

Query: 595 PKRPWLSATPSSGASAARQAGPA---PAAATAASKKFPGSAALVGAVRKPVVPSVPMASP 651
           PK P    TP   A   ++  P      A TA  K  P          K   P+ P   P
Sbjct: 415 PKEP-TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP-------TTPKEPAPTTP-KEP 465

Query: 652 APGRLGAMS-AAPSQPNSQIRQNIRRSLKE 680
           AP      S   P +P     ++   + KE
Sbjct: 466 APTTTKEPSPTTPKEPAPTTTKSAPTTTKE 495



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 79/354 (22%), Positives = 126/354 (35%), Gaps = 64/354 (18%)

Query: 345 ADGTDCTSIGTIEQKSSEDQGIKGRIEKAANPSGKKKLKIFQ--------------PVIE 390
           ++  + +S  +    SS  + IK     AAN   +KKLK+                PV++
Sbjct: 120 SENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVD 179

Query: 391 APGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMKMKPEKP 450
             G+   +  G   V  PD+    ++ +     +T   +++ K   P           +P
Sbjct: 180 EAGSG--LDNGDFKVTTPDTSTTQHNKV-----STSPKITTAKPINP-----------RP 221

Query: 451 SLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPSWASDHN 510
           SLP     +     +V+K    E KETT         ++   GKE    +S     S   
Sbjct: 222 SLPPNSDTSKETSLTVNKETTVETKETTTTN-----KQTSTDGKEKT--TSAKETQSIEK 274

Query: 511 YNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAP-----PGSAVGKQPAPRN 565
            +A    K  AP+  +L K T +   +  K  A+   K+  P     P S   K+P P  
Sbjct: 275 TSA----KDLAPTSKVLAKPTPK-AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 329

Query: 566 L-----VPKKSSFANVAAATPAIKKP-PSGFK---GTIPKRPWLSATPSSGASAARQAGP 616
           +      PK+ +     +A    K+P P+  K    T PK P  + T     +  + A  
Sbjct: 330 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT 389

Query: 617 APAAATAASKKFPGSAALVGAVRKPVVPSVPMAS----PAPGRLGAMSAAPSQP 666
            P      + K P  A        P  P  P  +    PAP         P +P
Sbjct: 390 TPKEPAPTTPKKP--APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 441



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 49/259 (18%), Positives = 76/259 (29%), Gaps = 7/259 (2%)

Query: 788  ESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAH 847
            E   T P++ A    E +P            +  P     P           TT +    
Sbjct: 417  EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 476

Query: 848  LFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAV 907
                     T   P+   EPAP   K + +  KE   +     AP    + A     +  
Sbjct: 477  TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 536

Query: 908  PEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRD 967
            P    EP   +   P    T  P P     P P+  ++ +P      +            
Sbjct: 537  PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 596

Query: 968  PRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSV 1027
             + AP++      +    P  T   E     PK    +   PK         P P   + 
Sbjct: 597  EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN--TPKEPAPTTPKEPAP---TT 651

Query: 1028 PPSPNISTSESRSP--PEG 1044
            P  P  +T +  +P  P+G
Sbjct: 652  PKEPAPTTPKETAPTTPKG 670



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 53/220 (24%), Positives = 77/220 (35%), Gaps = 28/220 (12%)

Query: 439 PKEKMKMKPEKPS--LPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEA 496
           P+E     PE+P+   PK  A       +  K PAP    TT K+      +  A     
Sbjct: 612 PEEPTPTTPEEPAPTTPKAAAP------NTPKEPAP----TTPKEPAPTTPKEPAPTTPK 661

Query: 497 ACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSA 556
               +TP   +        P     P+P  L  +T +    E  +        T P G+A
Sbjct: 662 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK----EPTSTTCDKPAPTTPKGTA 717

Query: 557 --VGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRP---WLSATPSSGASAA 611
               K+PAP    PK+ +        P   K P+    T PK+P    L+ T + G ++ 
Sbjct: 718 PTTPKEPAP--TTPKEPAPTTPKGTAPTTLKEPA---PTTPKKPAPKELAPTTTKGPTST 772

Query: 612 RQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASP 651
               PAP      +   P   A      K   P+ P   P
Sbjct: 773 TSDKPAPTTPKETAPTTPKEPA--PTTPKKPAPTTPETPP 810



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 64/263 (24%), Positives = 93/263 (35%), Gaps = 32/263 (12%)

Query: 372 KAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSS 431
           KAA P+  K+     P   AP   K   P       P +   +    LK  A T      
Sbjct: 629 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP---- 684

Query: 432 GKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEA 491
              +KP PKE      ++P+   C             +PAP   + T       PA +  
Sbjct: 685 ---KKPAPKELAPTTTKEPTSTTC------------DKPAPTTPKGTAPTTPKEPAPTTP 729

Query: 492 LGKEAACESSTPSWASDHNYNAVKPEKTAAPSP-SLLYKSTKEDRRSEEKAAAMAASKKT 550
             KE A   +TP   +        P     P+P  L   +TK    +     A    K+T
Sbjct: 730 --KEPA--PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 785

Query: 551 AP-----PGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSA--T 603
           AP     P     K+PAP        + + V+  T   K+P +  K      P LSA  T
Sbjct: 786 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT-TTKEPTTIHKSPDESTPELSAEPT 844

Query: 604 PSSGASAARQAGPAPAAATAASK 626
           P +  ++ ++ G       AA+K
Sbjct: 845 PKALENSPKEPGVPTTKTPAATK 867



 Score = 37.7 bits (86), Expect = 0.066
 Identities = 65/260 (25%), Positives = 90/260 (34%), Gaps = 34/260 (13%)

Query: 433 KEQKPKPKEKMKMKPEKPS--LPKCGAQAGIK--ISSVHKRPAPEKKE---TTVKKAVVV 485
           K     PKE     P+KP+   PK  A    K    +  K PAP  KE   TT K+    
Sbjct: 385 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 444

Query: 486 PARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKS---TKEDRRSEEKAA 542
             +  A         +TP   +        P     P+P+    +   TKE   +  K+A
Sbjct: 445 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 504

Query: 543 -------AMAASKKTAP-----PGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGF 590
                  +   +K+ AP     P     K+PAP    PK+ +        P   K P+  
Sbjct: 505 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP--TTPKEPAPTTPKEPAPTTTKKPA-- 560

Query: 591 KGTIPKRPWLSATPSSGASAARQ----AGPAPAAATAASKKFPGSAALVGAVRKPVVPSV 646
             T PK P    TP   A    +      P   A T   K  P +   + A   P  P+ 
Sbjct: 561 -PTTPKEP-APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL-APTTPEEPT- 616

Query: 647 PMASPAPGRLGAMSAAPSQP 666
           P     P      +AAP+ P
Sbjct: 617 PTTPEEPAPTTPKAAAPNTP 636



 Score = 32.7 bits (73), Expect = 2.1
 Identities = 67/298 (22%), Positives = 97/298 (32%), Gaps = 72/298 (24%)

Query: 422  AAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKK 481
            A  T K  +S    KP P    +  P  P  P           +  K+PAP   ET    
Sbjct: 762  APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA---------PTTPKKPAPTTPETPP-- 810

Query: 482  AVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKA 541
                P  SE        E +T   + D +     PE +A P+P  L  S KE      K 
Sbjct: 811  ----PTTSEVSTPTTTKEPTTIHKSPDES----TPELSAEPTPKALENSPKEPGVPTTKT 862

Query: 542  AA-----MAASKKTAPPGSAVGKQPAPRNLVPK----------KSSFANVAAATPAI--- 583
             A     M  + K       +   P      PK          K++ + + A T  +   
Sbjct: 863  PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTST 922

Query: 584  -KKPPSGFKGT----------------------IPKRPWLSATPSSGASAARQAGPAPAA 620
              +  + FK T                      I  +P  +A P   A+ ++   P P  
Sbjct: 923  TTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK 982

Query: 621  ATAASKKFPGSA---ALVGAVRKP--------VVPSVPMASPAPGRLGAMSAAPSQPN 667
             T A KK P S      +  VRKP        +  ++P  +P      AM    ++PN
Sbjct: 983  PTKAPKK-PTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPN 1039



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 38/194 (19%), Positives = 69/194 (35%), Gaps = 19/194 (9%)

Query: 861  PSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPA-PDSADEVMPEAVPEVASEPGLESA 919
            P+  + P P   ++S     ++  + H S  PD + P+ + E  P+A+     EPG+ + 
Sbjct: 803  PTTPETPPPTTSEVSTPTTTKEPTTIHKS--PDESTPELSAEPTPKALENSPKEPGVPTT 860

Query: 920  SHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSG------VVTTVTVSGRDPRTAPS 973
              P   +        D   E     DL   P +  +         TT   +     TA +
Sbjct: 861  KTPAATKPEMTTTAKDKTTE----RDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 916

Query: 974  SSCTAVASAASRPDSTHMVEARQDVPKPVLT-SVMVPKSILAKPSSSPDPR-----YLSV 1027
            +  T+  +  + P     ++     PK   T   +    I+ KP  +  P+       + 
Sbjct: 917  TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT 976

Query: 1028 PPSPNISTSESRSP 1041
             P P   T   + P
Sbjct: 977  TPKPQKPTKAPKKP 990


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 97/517 (18%), Positives = 161/517 (31%), Gaps = 34/517 (6%)

Query: 546  ASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPS 605
            +SKK  PP  A     +     PK     N       I+      + ++ +    S++ S
Sbjct: 115  SSKKAPPPSGASQTIKSTTKRSPKPP---NKKKTKKVIESEEITEEHSVSENQESSSSSS 171

Query: 606  SGASAAR----QAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSA 661
            S +S++     ++    AA     KK           +K   P  P+   A   L     
Sbjct: 172  SSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDF 231

Query: 662  APSQPNSQIRQN--IRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDN 719
              + P++   Q+  +  S K    K +N    L    +   + +L + KE     + T  
Sbjct: 232  KVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTT 291

Query: 720  RYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVM 779
              K             K      +   ++++    V  KP    + +  T  + PA +  
Sbjct: 292  TNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP----TPKAETTTKGPALTTP 347

Query: 780  ESRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKD 839
            +  T    +   +   +E  P    S P +  E    + ++ P     P           
Sbjct: 348  KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 407

Query: 840  TTSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSA 899
            T  +             T   P+   EPAP   K  A       K    ++  +P P + 
Sbjct: 408  TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP---KEPAPTTPKEPTPTTP 464

Query: 900  DEVMP---EAVPEVASEPGLESASHPNVDRTYFPGPPGDGHP------EPSPLEDLSPCP 950
             E  P   E  P    EP   +   P       P P     P      EPSP     P P
Sbjct: 465  KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 524

Query: 951  ASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPK------PVLT 1004
             +  S   TT   +    ++AP++      +    P  T   E     PK      P   
Sbjct: 525  TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 584

Query: 1005 SVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSP 1041
            +   PK      +  P P   + P  P  +T +  +P
Sbjct: 585  APTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAP 618



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 68/270 (25%), Positives = 98/270 (36%), Gaps = 33/270 (12%)

Query: 425 TMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVV 484
           T +  ++ K+     KEK     E  S+ K  A+     S V  +P P+ + TT   A+ 
Sbjct: 286 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT 345

Query: 485 VPAR-SEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAA 543
            P   +    KE A  S+TP    +     +K   T    P+    +T +   +  K  A
Sbjct: 346 TPKEPTPTTPKEPA--STTP---KEPTPTTIKSAPTTPKEPA---PTTTKSAPTTPKEPA 397

Query: 544 MAASKKTAP-----PGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKP----PSGFKGTI 594
              +K+ AP     P     K+PAP       ++    A  TP  KKP    P     T 
Sbjct: 398 PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP--KKPAPTTPKEPAPTT 455

Query: 595 PKRPWLSATPSSGASAARQAGPA---PAAATAASKKFPGSAALVGAVRKPVVPSVPMASP 651
           PK P    TP   A   ++  P      A TA  K  P          K   P+ P   P
Sbjct: 456 PKEP-TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP-------TTPKEPAPTTP-KEP 506

Query: 652 APGRLGAMS-AAPSQPNSQIRQNIRRSLKE 680
           AP      S   P +P     ++   + KE
Sbjct: 507 APTTTKEPSPTTPKEPAPTTTKSAPTTTKE 536



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 79/354 (22%), Positives = 126/354 (35%), Gaps = 64/354 (18%)

Query: 345 ADGTDCTSIGTIEQKSSEDQGIKGRIEKAANPSGKKKLKIFQ--------------PVIE 390
           ++  + +S  +    SS  + IK     AAN   +KKLK+                PV++
Sbjct: 161 SENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVD 220

Query: 391 APGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMKMKPEKP 450
             G+   +  G   V  PD+    ++ +     +T   +++ K   P           +P
Sbjct: 221 EAGSG--LDNGDFKVTTPDTSTTQHNKV-----STSPKITTAKPINP-----------RP 262

Query: 451 SLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPSWASDHN 510
           SLP     +     +V+K    E KETT         ++   GKE    +S     S   
Sbjct: 263 SLPPNSDTSKETSLTVNKETTVETKETTTTN-----KQTSTDGKEKT--TSAKETQSIEK 315

Query: 511 YNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAP-----PGSAVGKQPAPRN 565
            +A    K  AP+  +L K T +   +  K  A+   K+  P     P S   K+P P  
Sbjct: 316 TSA----KDLAPTSKVLAKPTPK-AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 370

Query: 566 L-----VPKKSSFANVAAATPAIKKP-PSGFK---GTIPKRPWLSATPSSGASAARQAGP 616
           +      PK+ +     +A    K+P P+  K    T PK P  + T     +  + A  
Sbjct: 371 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT 430

Query: 617 APAAATAASKKFPGSAALVGAVRKPVVPSVPMAS----PAPGRLGAMSAAPSQP 666
            P      + K P  A        P  P  P  +    PAP         P +P
Sbjct: 431 TPKEPAPTTPKKP--APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 482



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 49/259 (18%), Positives = 76/259 (29%), Gaps = 7/259 (2%)

Query: 788  ESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAH 847
            E   T P++ A    E +P            +  P     P           TT +    
Sbjct: 458  EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 517

Query: 848  LFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAV 907
                     T   P+   EPAP   K + +  KE   +     AP    + A     +  
Sbjct: 518  TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 577

Query: 908  PEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRD 967
            P    EP   +   P    T  P P     P P+  ++ +P      +            
Sbjct: 578  PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 637

Query: 968  PRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSV 1027
             + AP++      +    P  T   E     PK    +   PK         P P   + 
Sbjct: 638  EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN--TPKEPAPTTPKEPAP---TT 692

Query: 1028 PPSPNISTSESRSP--PEG 1044
            P  P  +T +  +P  P+G
Sbjct: 693  PKEPAPTTPKETAPTTPKG 711



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 53/220 (24%), Positives = 77/220 (35%), Gaps = 28/220 (12%)

Query: 439 PKEKMKMKPEKPS--LPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEA 496
           P+E     PE+P+   PK  A       +  K PAP    TT K+      +  A     
Sbjct: 653 PEEPTPTTPEEPAPTTPKAAAP------NTPKEPAP----TTPKEPAPTTPKEPAPTTPK 702

Query: 497 ACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSA 556
               +TP   +        P     P+P  L  +T +    E  +        T P G+A
Sbjct: 703 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK----EPTSTTCDKPAPTTPKGTA 758

Query: 557 --VGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRP---WLSATPSSGASAA 611
               K+PAP    PK+ +        P   K P+    T PK+P    L+ T + G ++ 
Sbjct: 759 PTTPKEPAP--TTPKEPAPTTPKGTAPTTLKEPA---PTTPKKPAPKELAPTTTKGPTST 813

Query: 612 RQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASP 651
               PAP      +   P   A      K   P+ P   P
Sbjct: 814 TSDKPAPTTPKETAPTTPKEPA--PTTPKKPAPTTPETPP 851



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 64/263 (24%), Positives = 93/263 (35%), Gaps = 32/263 (12%)

Query: 372 KAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSS 431
           KAA P+  K+     P   AP   K   P       P +   +    LK  A T      
Sbjct: 670 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP---- 725

Query: 432 GKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEA 491
              +KP PKE      ++P+   C             +PAP   + T       PA +  
Sbjct: 726 ---KKPAPKELAPTTTKEPTSTTC------------DKPAPTTPKGTAPTTPKEPAPTTP 770

Query: 492 LGKEAACESSTPSWASDHNYNAVKPEKTAAPSP-SLLYKSTKEDRRSEEKAAAMAASKKT 550
             KE A   +TP   +        P     P+P  L   +TK    +     A    K+T
Sbjct: 771 --KEPA--PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 826

Query: 551 AP-----PGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSA--T 603
           AP     P     K+PAP        + + V+  T   K+P +  K      P LSA  T
Sbjct: 827 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT-TTKEPTTIHKSPDESTPELSAEPT 885

Query: 604 PSSGASAARQAGPAPAAATAASK 626
           P +  ++ ++ G       AA+K
Sbjct: 886 PKALENSPKEPGVPTTKTPAATK 908



 Score = 37.7 bits (86), Expect = 0.066
 Identities = 65/260 (25%), Positives = 90/260 (34%), Gaps = 34/260 (13%)

Query: 433 KEQKPKPKEKMKMKPEKPS--LPKCGAQAGIK--ISSVHKRPAPEKKE---TTVKKAVVV 485
           K     PKE     P+KP+   PK  A    K    +  K PAP  KE   TT K+    
Sbjct: 426 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 485

Query: 486 PARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKS---TKEDRRSEEKAA 542
             +  A         +TP   +        P     P+P+    +   TKE   +  K+A
Sbjct: 486 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 545

Query: 543 -------AMAASKKTAP-----PGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGF 590
                  +   +K+ AP     P     K+PAP    PK+ +        P   K P+  
Sbjct: 546 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP--TTPKEPAPTTPKEPAPTTTKKPA-- 601

Query: 591 KGTIPKRPWLSATPSSGASAARQ----AGPAPAAATAASKKFPGSAALVGAVRKPVVPSV 646
             T PK P    TP   A    +      P   A T   K  P +   + A   P  P+ 
Sbjct: 602 -PTTPKEP-APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL-APTTPEEPT- 657

Query: 647 PMASPAPGRLGAMSAAPSQP 666
           P     P      +AAP+ P
Sbjct: 658 PTTPEEPAPTTPKAAAPNTP 677



 Score = 32.7 bits (73), Expect = 2.1
 Identities = 67/298 (22%), Positives = 97/298 (32%), Gaps = 72/298 (24%)

Query: 422  AAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKK 481
            A  T K  +S    KP P    +  P  P  P           +  K+PAP   ET    
Sbjct: 803  APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA---------PTTPKKPAPTTPETPP-- 851

Query: 482  AVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKA 541
                P  SE        E +T   + D +     PE +A P+P  L  S KE      K 
Sbjct: 852  ----PTTSEVSTPTTTKEPTTIHKSPDES----TPELSAEPTPKALENSPKEPGVPTTKT 903

Query: 542  AA-----MAASKKTAPPGSAVGKQPAPRNLVPK----------KSSFANVAAATPAI--- 583
             A     M  + K       +   P      PK          K++ + + A T  +   
Sbjct: 904  PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTST 963

Query: 584  -KKPPSGFKGT----------------------IPKRPWLSATPSSGASAARQAGPAPAA 620
              +  + FK T                      I  +P  +A P   A+ ++   P P  
Sbjct: 964  TTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK 1023

Query: 621  ATAASKKFPGSA---ALVGAVRKP--------VVPSVPMASPAPGRLGAMSAAPSQPN 667
             T A KK P S      +  VRKP        +  ++P  +P      AM    ++PN
Sbjct: 1024 PTKAPKK-PTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPN 1080



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 38/194 (19%), Positives = 69/194 (35%), Gaps = 19/194 (9%)

Query: 861  PSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPA-PDSADEVMPEAVPEVASEPGLESA 919
            P+  + P P   ++S     ++  + H S  PD + P+ + E  P+A+     EPG+ + 
Sbjct: 844  PTTPETPPPTTSEVSTPTTTKEPTTIHKS--PDESTPELSAEPTPKALENSPKEPGVPTT 901

Query: 920  SHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSG------VVTTVTVSGRDPRTAPS 973
              P   +        D   E     DL   P +  +         TT   +     TA +
Sbjct: 902  KTPAATKPEMTTTAKDKTTE----RDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 957

Query: 974  SSCTAVASAASRPDSTHMVEARQDVPKPVLT-SVMVPKSILAKPSSSPDPR-----YLSV 1027
            +  T+  +  + P     ++     PK   T   +    I+ KP  +  P+       + 
Sbjct: 958  TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT 1017

Query: 1028 PPSPNISTSESRSP 1041
             P P   T   + P
Sbjct: 1018 TPKPQKPTKAPKKP 1031


>gi|239749424 PREDICTED: hypothetical protein XP_002347041 [Homo
           sapiens]
          Length = 287

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 33/114 (28%), Positives = 57/114 (50%), Gaps = 2/114 (1%)

Query: 659 MSAAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTD 718
           +S+ P  P++    ++R   +E+L   +   DD I    +  ++   IE+ ++   + TD
Sbjct: 113 VSSFPRAPSTS--DSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTD 170

Query: 719 NRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKE 772
            +YK++ RS + NLKD KN  L   VL   I      R+  EE+ S EL   ++
Sbjct: 171 MKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRK 224


>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
           sapiens]
          Length = 1858

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 34/136 (25%), Positives = 52/136 (38%), Gaps = 22/136 (16%)

Query: 214 PSKQEPENDQGVVSQAGKDDRESKLEGKAAQDIKDEEPGDLGRPKPECEGYDPNALYCIC 273
           PS    +N+ G+ +    D+  S      A  I   E G           Y  +   CIC
Sbjct: 80  PSVLISKNEVGIFTTPNFDETSS------ATTISTSEDGS----------YGTDVTRCIC 123

Query: 274 RQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDETHSETA 333
              H++ +MICCD+C  W H DC+GI        +   + Y+C  C    +  E      
Sbjct: 124 GFTHDDGYMICCDKCSVWQHIDCMGIDR------QHIPDTYLCERCQPRNLDKERAVLLQ 177

Query: 334 DQQEAKWRPGDADGTD 349
            ++      GD   T+
Sbjct: 178 RRKRENMSDGDTSATE 193


>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
           sapiens]
          Length = 1858

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 34/136 (25%), Positives = 52/136 (38%), Gaps = 22/136 (16%)

Query: 214 PSKQEPENDQGVVSQAGKDDRESKLEGKAAQDIKDEEPGDLGRPKPECEGYDPNALYCIC 273
           PS    +N+ G+ +    D+  S      A  I   E G           Y  +   CIC
Sbjct: 80  PSVLISKNEVGIFTTPNFDETSS------ATTISTSEDGS----------YGTDVTRCIC 123

Query: 274 RQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDETHSETA 333
              H++ +MICCD+C  W H DC+GI        +   + Y+C  C    +  E      
Sbjct: 124 GFTHDDGYMICCDKCSVWQHIDCMGIDR------QHIPDTYLCERCQPRNLDKERAVLLQ 177

Query: 334 DQQEAKWRPGDADGTD 349
            ++      GD   T+
Sbjct: 178 RRKRENMSDGDTSATE 193


>gi|5803191 transcription elongation factor A 1 isoform 1 [Homo
           sapiens]
          Length = 301

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 33/114 (28%), Positives = 57/114 (50%), Gaps = 2/114 (1%)

Query: 659 MSAAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTD 718
           +S+ P  P++    ++R   +E+L   +   DD I    +  ++   IE+ ++   + TD
Sbjct: 127 VSSFPRAPSTS--DSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTD 184

Query: 719 NRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKE 772
            +YK++ RS + NLKD KN  L   VL   I      R+  EE+ S EL   ++
Sbjct: 185 MKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRK 238


>gi|45439355 transcription elongation factor A 1 isoform 2 [Homo
           sapiens]
          Length = 280

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 33/114 (28%), Positives = 57/114 (50%), Gaps = 2/114 (1%)

Query: 659 MSAAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTD 718
           +S+ P  P++    ++R   +E+L   +   DD I    +  ++   IE+ ++   + TD
Sbjct: 106 VSSFPRAPSTS--DSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTD 163

Query: 719 NRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKE 772
            +YK++ RS + NLKD KN  L   VL   I      R+  EE+ S EL   ++
Sbjct: 164 MKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRK 217


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 118/554 (21%), Positives = 195/554 (35%), Gaps = 82/554 (14%)

Query: 139 SEKVKGGDDHDDTSDSDSDGLTLKE--LQNRLRRKREQEPTERPLKGIQSRLRKKRREEG 196
           S+ +   D+ DD  D D+D   + E  L+ +   K + E  E+P + IQ+++  K +E+G
Sbjct: 111 SDIISSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKG 170

Query: 197 P---AETVGSEASDTVEGVLPSKQEPE-----NDQGVVSQAGKDDRESKLEGKAAQDIKD 248
                E    E   T +  +  K++PE      +Q     A K + ++K E K  +  K 
Sbjct: 171 KEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKV 230

Query: 249 EEPG----DLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARG 304
           ++      ++ +   + +  +      + +    +++  C    + + HGD         
Sbjct: 231 KQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGD--------- 281

Query: 305 RLLERNGEDYICPNCTILQVQDETHSETA-DQQEAKWRPGDADGTDCTSIGTIEQKSSED 363
             L+      I P     Q    T +  A +++E + +  +   T        E K  E 
Sbjct: 282 --LKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTS-------ETKKKEK 332

Query: 364 QGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAA 423
           + IK + EK      +KK          PG +     G   +A         D   + + 
Sbjct: 333 EDIKKKSEKETAIDVEKK---------EPGKASETKQGTVKIAA--QAAAKKDEKKEDSK 381

Query: 424 ATMKFLS----SGKEQKPKPK--EKMKMKPEKPSLPK------CGAQAGIKISSVH-KRP 470
            T K        GK+Q+ K K  E  K   ++ S+P          +A  +I +V  K+ 
Sbjct: 382 KTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKA 441

Query: 471 APEKKETTVKKAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKS 530
            P KKE    K V    R E  GK       T S   D      K EK  A       K 
Sbjct: 442 VPGKKEEKTTKTVEQEIRKEKSGK-------TSSILKDKEPIKGKEEKVPAS-----LKE 489

Query: 531 TKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGF 590
            + + + +EK +      K  PP     K+  P   + K+        A PAI +     
Sbjct: 490 KEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKE--------AKPAISEKVQIH 541

Query: 591 KGTIPKRPWLSATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMAS 650
           K  I K      T S G    +      A     + K   +       R+P  PS+    
Sbjct: 542 KQDIVKP---EKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREP--PSIKTDK 596

Query: 651 PAPGRLGAMSAAPS 664
           P P   G      S
Sbjct: 597 PKPTPKGTSEVTES 610


>gi|197276602 microtubule-associated protein 4 isoform 5 [Homo
           sapiens]
          Length = 817

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 66/267 (24%), Positives = 103/267 (38%), Gaps = 31/267 (11%)

Query: 433 KEQKPKPKEKMK----MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAV----- 483
           KE  P P++K K     +P K S  K   Q     +S+ K+PAP       KK +     
Sbjct: 426 KELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMSLASG 481

Query: 484 VVPARSEALGKEAACESSTPSWASDHNY------NAVKPEKTAAPSPSLLYKSTKEDRRS 537
           +VPA   A  K  A  S+ PS     +       +A  PEK A+PS      +++   +S
Sbjct: 482 LVPA---APPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS 538

Query: 538 EEKAAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKR 597
            +  A    +   A  G +     +P  L+PKK +          +KK  +        R
Sbjct: 539 TQTVAKTTTAAAVASTGPS---SRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSR 595

Query: 598 PWLSATPSSGASAARQAGPAPAAATAASK----KFPGSAALVGAV-RKPVVPSVPMASPA 652
           P  S + SS       +G APAA    S+      P   +    + +KP        +P 
Sbjct: 596 P-KSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPR 654

Query: 653 PGRLGAMSAAPSQPNSQIRQNIRRSLK 679
             RL   ++AP   N + +     ++K
Sbjct: 655 LSRLATNTSAPDLKNVRSKVGSTENIK 681



 Score = 34.3 bits (77), Expect = 0.73
 Identities = 58/244 (23%), Positives = 85/244 (34%), Gaps = 53/244 (21%)

Query: 822  PEKSTAPLLDVFSSMLKDTTSQHRAH------------LFDLNCK---ICTGQVPSAEDE 866
            PEK T PL    +   K +TS+ +              +  LN K   + +G VP+A   
Sbjct: 432  PEKKTKPLAT--TQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAA--- 486

Query: 867  PAPKKQKLSASVKKEDLKSKH-------DSSAPD-----------PAPDSADEVMPEAVP 908
              P K+   AS +   L SK        D+ AP+           PA  S  +       
Sbjct: 487  --PPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAK 544

Query: 909  EVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLE-----------DLSPCPASCGSGV 957
               +     +        T  P  P     E  P E           DLS   ++  S +
Sbjct: 545  TTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSM 604

Query: 958  VTTVTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPS 1017
              T T+SG  P      S        SRP +T  ++ +    KP  T+  +  S LA  +
Sbjct: 605  KKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRL--SRLATNT 662

Query: 1018 SSPD 1021
            S+PD
Sbjct: 663  SAPD 666


>gi|197276600 microtubule-associated protein 4 isoform 4 [Homo
           sapiens]
          Length = 1135

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 66/267 (24%), Positives = 103/267 (38%), Gaps = 31/267 (11%)

Query: 433 KEQKPKPKEKMK----MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAV----- 483
           KE  P P++K K     +P K S  K   Q     +S+ K+PAP       KK +     
Sbjct: 691 KELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMSLASG 746

Query: 484 VVPARSEALGKEAACESSTPSWASDHNY------NAVKPEKTAAPSPSLLYKSTKEDRRS 537
           +VPA   A  K  A  S+ PS     +       +A  PEK A+PS      +++   +S
Sbjct: 747 LVPA---APPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS 803

Query: 538 EEKAAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKR 597
            +  A    +   A  G +     +P  L+PKK +          +KK  +        R
Sbjct: 804 TQTVAKTTTAAAVASTGPS---SRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSR 860

Query: 598 PWLSATPSSGASAARQAGPAPAAATAASK----KFPGSAALVGAV-RKPVVPSVPMASPA 652
           P  S + SS       +G APAA    S+      P   +    + +KP        +P 
Sbjct: 861 P-KSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPR 919

Query: 653 PGRLGAMSAAPSQPNSQIRQNIRRSLK 679
             RL   ++AP   N + +     ++K
Sbjct: 920 LSRLATNTSAPDLKNVRSKVGSTENIK 946



 Score = 34.3 bits (77), Expect = 0.73
 Identities = 58/244 (23%), Positives = 85/244 (34%), Gaps = 53/244 (21%)

Query: 822  PEKSTAPLLDVFSSMLKDTTSQHRAH------------LFDLNCK---ICTGQVPSAEDE 866
            PEK T PL    +   K +TS+ +              +  LN K   + +G VP+A   
Sbjct: 697  PEKKTKPLAT--TQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAA--- 751

Query: 867  PAPKKQKLSASVKKEDLKSKH-------DSSAPD-----------PAPDSADEVMPEAVP 908
              P K+   AS +   L SK        D+ AP+           PA  S  +       
Sbjct: 752  --PPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAK 809

Query: 909  EVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLE-----------DLSPCPASCGSGV 957
               +     +        T  P  P     E  P E           DLS   ++  S +
Sbjct: 810  TTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSM 869

Query: 958  VTTVTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPS 1017
              T T+SG  P      S        SRP +T  ++ +    KP  T+  +  S LA  +
Sbjct: 870  KKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRL--SRLATNT 927

Query: 1018 SSPD 1021
            S+PD
Sbjct: 928  SAPD 931


>gi|47519675 microtubule-associated protein 4 isoform 2 [Homo
           sapiens]
          Length = 887

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 66/267 (24%), Positives = 103/267 (38%), Gaps = 31/267 (11%)

Query: 433 KEQKPKPKEKMK----MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAV----- 483
           KE  P P++K K     +P K S  K   Q     +S+ K+PAP       KK +     
Sbjct: 426 KELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMSLASG 481

Query: 484 VVPARSEALGKEAACESSTPSWASDHNY------NAVKPEKTAAPSPSLLYKSTKEDRRS 537
           +VPA   A  K  A  S+ PS     +       +A  PEK A+PS      +++   +S
Sbjct: 482 LVPA---APPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS 538

Query: 538 EEKAAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKR 597
            +  A    +   A  G +     +P  L+PKK +          +KK  +        R
Sbjct: 539 TQTVAKTTTAAAVASTGPS---SRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSR 595

Query: 598 PWLSATPSSGASAARQAGPAPAAATAASK----KFPGSAALVGAV-RKPVVPSVPMASPA 652
           P  S + SS       +G APAA    S+      P   +    + +KP        +P 
Sbjct: 596 P-KSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPR 654

Query: 653 PGRLGAMSAAPSQPNSQIRQNIRRSLK 679
             RL   ++AP   N + +     ++K
Sbjct: 655 LSRLATNTSAPDLKNVRSKVGSTENIK 681



 Score = 34.3 bits (77), Expect = 0.73
 Identities = 58/244 (23%), Positives = 85/244 (34%), Gaps = 53/244 (21%)

Query: 822  PEKSTAPLLDVFSSMLKDTTSQHRAH------------LFDLNCK---ICTGQVPSAEDE 866
            PEK T PL    +   K +TS+ +              +  LN K   + +G VP+A   
Sbjct: 432  PEKKTKPLAT--TQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAA--- 486

Query: 867  PAPKKQKLSASVKKEDLKSKH-------DSSAPD-----------PAPDSADEVMPEAVP 908
              P K+   AS +   L SK        D+ AP+           PA  S  +       
Sbjct: 487  --PPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAK 544

Query: 909  EVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLE-----------DLSPCPASCGSGV 957
               +     +        T  P  P     E  P E           DLS   ++  S +
Sbjct: 545  TTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSM 604

Query: 958  VTTVTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPS 1017
              T T+SG  P      S        SRP +T  ++ +    KP  T+  +  S LA  +
Sbjct: 605  KKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRL--SRLATNT 662

Query: 1018 SSPD 1021
            S+PD
Sbjct: 663  SAPD 666


>gi|47519639 microtubule-associated protein 4 isoform 1 [Homo
           sapiens]
          Length = 1152

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 66/267 (24%), Positives = 103/267 (38%), Gaps = 31/267 (11%)

Query: 433 KEQKPKPKEKMK----MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAV----- 483
           KE  P P++K K     +P K S  K   Q     +S+ K+PAP       KK +     
Sbjct: 691 KELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMSLASG 746

Query: 484 VVPARSEALGKEAACESSTPSWASDHNY------NAVKPEKTAAPSPSLLYKSTKEDRRS 537
           +VPA   A  K  A  S+ PS     +       +A  PEK A+PS      +++   +S
Sbjct: 747 LVPA---APPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS 803

Query: 538 EEKAAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKR 597
            +  A    +   A  G +     +P  L+PKK +          +KK  +        R
Sbjct: 804 TQTVAKTTTAAAVASTGPS---SRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSR 860

Query: 598 PWLSATPSSGASAARQAGPAPAAATAASK----KFPGSAALVGAV-RKPVVPSVPMASPA 652
           P  S + SS       +G APAA    S+      P   +    + +KP        +P 
Sbjct: 861 P-KSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPR 919

Query: 653 PGRLGAMSAAPSQPNSQIRQNIRRSLK 679
             RL   ++AP   N + +     ++K
Sbjct: 920 LSRLATNTSAPDLKNVRSKVGSTENIK 946



 Score = 34.3 bits (77), Expect = 0.73
 Identities = 58/244 (23%), Positives = 85/244 (34%), Gaps = 53/244 (21%)

Query: 822  PEKSTAPLLDVFSSMLKDTTSQHRAH------------LFDLNCK---ICTGQVPSAEDE 866
            PEK T PL    +   K +TS+ +              +  LN K   + +G VP+A   
Sbjct: 697  PEKKTKPLAT--TQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAA--- 751

Query: 867  PAPKKQKLSASVKKEDLKSKH-------DSSAPD-----------PAPDSADEVMPEAVP 908
              P K+   AS +   L SK        D+ AP+           PA  S  +       
Sbjct: 752  --PPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAK 809

Query: 909  EVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLE-----------DLSPCPASCGSGV 957
               +     +        T  P  P     E  P E           DLS   ++  S +
Sbjct: 810  TTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSM 869

Query: 958  VTTVTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPS 1017
              T T+SG  P      S        SRP +T  ++ +    KP  T+  +  S LA  +
Sbjct: 870  KKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRL--SRLATNT 927

Query: 1018 SSPD 1021
            S+PD
Sbjct: 928  SAPD 931


>gi|38505156 transcription elongation factor A protein 2 isoform b
           [Homo sapiens]
          Length = 272

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 45/174 (25%), Positives = 72/174 (41%), Gaps = 19/174 (10%)

Query: 597 RPWLSATPSSGASAARQAG---PAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAP 653
           + W     +S A A R+ G   P P ++  AS+    S       R P  P +    P P
Sbjct: 47  KSWKKLLDASDAKA-RERGRGMPLPTSSRDASEAPDPSRKRPELPRAPSTPRITTFPPVP 105

Query: 654 GRLGAMSAAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNL 713
               A               +R   +E+L   +    D +    +  +++  IE+ +F  
Sbjct: 106 VTCDA---------------VRNKCREMLTAALQTDHDHVAIGADCERLSAQIEECIFRD 150

Query: 714 FQVTDNRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKEL 767
              TD +YK++ RS + NLKD KN  L   VL   I+  ++  +  EE+ S EL
Sbjct: 151 VGNTDMKYKNRVRSRISNLKDAKNPDLRRNVLCGAITPQQIAVMTSEEMASDEL 204


>gi|4507385 transcription elongation factor A protein 2 isoform a
           [Homo sapiens]
          Length = 299

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 45/174 (25%), Positives = 72/174 (41%), Gaps = 19/174 (10%)

Query: 597 RPWLSATPSSGASAARQAG---PAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAP 653
           + W     +S A A R+ G   P P ++  AS+    S       R P  P +    P P
Sbjct: 74  KSWKKLLDASDAKA-RERGRGMPLPTSSRDASEAPDPSRKRPELPRAPSTPRITTFPPVP 132

Query: 654 GRLGAMSAAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNL 713
               A               +R   +E+L   +    D +    +  +++  IE+ +F  
Sbjct: 133 VTCDA---------------VRNKCREMLTAALQTDHDHVAIGADCERLSAQIEECIFRD 177

Query: 714 FQVTDNRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKEL 767
              TD +YK++ RS + NLKD KN  L   VL   I+  ++  +  EE+ S EL
Sbjct: 178 VGNTDMKYKNRVRSRISNLKDAKNPDLRRNVLCGAITPQQIAVMTSEEMASDEL 231


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.127    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,600,991
Number of Sequences: 37866
Number of extensions: 3060163
Number of successful extensions: 18300
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 114
Number of HSP's successfully gapped in prelim test: 1003
Number of HSP's that attempted gapping in prelim test: 14259
Number of HSP's gapped (non-prelim): 4665
length of query: 1189
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1076
effective length of database: 13,968,660
effective search space: 15030278160
effective search space used: 15030278160
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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