Guide to the Human Genome
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Search of human proteins with 70909338

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|70909338 SRY (sex determining region Y)-box 6 isoform 1
[Homo sapiens]
         (804 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo...  1605   0.0  
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom...  1598   0.0  
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom...  1540   0.0  
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo...  1483   0.0  
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo...   845   0.0  
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo...   843   0.0  
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo...   422   e-118
gi|41406089 SRY-box 13 [Homo sapiens]                                 361   1e-99
gi|11967991 SRY-box 17 [Homo sapiens]                                 109   1e-23
gi|13899269 SRY-box 7 [Homo sapiens]                                  105   2e-22
gi|8924248 SRY-box 18 [Homo sapiens]                                  104   4e-22
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]        103   5e-22
gi|4507161 SRY-box 11 [Homo sapiens]                                  103   8e-22
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]       102   2e-21
gi|4759162 SRY-box 14 [Homo sapiens]                                  100   4e-21
gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]      100   5e-21
gi|28195386 sex-determining region Y-box 2 [Homo sapiens]             100   7e-21
gi|5902108 SRY-box 21 [Homo sapiens]                                   99   1e-20
gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]        99   2e-20
gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]        98   3e-20
gi|4557853 transcription factor SOX9 [Homo sapiens]                    97   5e-20
gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]        97   5e-20
gi|4507225 sex determining region Y [Homo sapiens]                     97   8e-20
gi|5902106 SRY-box 15 [Homo sapiens]                                   95   2e-19
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom...    88   4e-17
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo...    83   9e-16
gi|112421108 capicua homolog [Homo sapiens]                            68   3e-11
gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens]    66   1e-10
gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens]    66   1e-10
gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens]    66   1e-10

>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
           sapiens]
          Length = 804

 Score = 1605 bits (4155), Expect = 0.0
 Identities = 804/804 (100%), Positives = 804/804 (100%)

Query: 1   MGRMSSKQATSPFACAADGEDAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELP 60
           MGRMSSKQATSPFACAADGEDAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELP
Sbjct: 1   MGRMSSKQATSPFACAADGEDAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELP 60

Query: 61  TLVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTF 120
           TLVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTF
Sbjct: 61  TLVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTF 120

Query: 121 GTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEI 180
           GTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEI
Sbjct: 121 GTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEI 180

Query: 181 KGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQI 240
           KGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQI
Sbjct: 181 KGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQI 240

Query: 241 ARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITY 300
           ARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITY
Sbjct: 241 ARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITY 300

Query: 301 KPGDNYPVQFIPSTMAAAAASGLSPLQLQQLYAAQLASMQVSPGAKMPSTPQPPNTAGTV 360
           KPGDNYPVQFIPSTMAAAAASGLSPLQLQQLYAAQLASMQVSPGAKMPSTPQPPNTAGTV
Sbjct: 301 KPGDNYPVQFIPSTMAAAAASGLSPLQLQQLYAAQLASMQVSPGAKMPSTPQPPNTAGTV 360

Query: 361 SPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNL 420
           SPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNL
Sbjct: 361 SPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNL 420

Query: 421 PNKSSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKAIQEAR 480
           PNKSSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKAIQEAR
Sbjct: 421 PNKSSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKAIQEAR 480

Query: 481 KMREQIQREQQQQQPHGVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLG 540
           KMREQIQREQQQQQPHGVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLG
Sbjct: 481 KMREQIQREQQQQQPHGVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLG 540

Query: 541 PGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRP 600
           PGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRP
Sbjct: 541 PGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRP 600

Query: 601 MNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEK 660
           MNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEK
Sbjct: 601 MNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEK 660

Query: 661 YPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYP 720
           YPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYP
Sbjct: 661 YPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYP 720

Query: 721 GAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMY 780
           GAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMY
Sbjct: 721 GAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMY 780

Query: 781 DDYEDDPKSDYSSENEAPEAVSAN 804
           DDYEDDPKSDYSSENEAPEAVSAN
Sbjct: 781 DDYEDDPKSDYSSENEAPEAVSAN 804


>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
           sapiens]
          Length = 801

 Score = 1598 bits (4139), Expect = 0.0
 Identities = 801/801 (100%), Positives = 801/801 (100%)

Query: 4   MSSKQATSPFACAADGEDAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTLV 63
           MSSKQATSPFACAADGEDAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTLV
Sbjct: 1   MSSKQATSPFACAADGEDAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTLV 60

Query: 64  STIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGTP 123
           STIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGTP
Sbjct: 61  STIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGTP 120

Query: 124 ERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGT 183
           ERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGT
Sbjct: 121 ERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGT 180

Query: 184 PESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQ 243
           PESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQ
Sbjct: 181 PESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQ 240

Query: 244 QQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPG 303
           QQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPG
Sbjct: 241 QQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPG 300

Query: 304 DNYPVQFIPSTMAAAAASGLSPLQLQQLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPT 363
           DNYPVQFIPSTMAAAAASGLSPLQLQQLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPT
Sbjct: 301 DNYPVQFIPSTMAAAAASGLSPLQLQQLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPT 360

Query: 364 GIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNK 423
           GIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNK
Sbjct: 361 GIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNK 420

Query: 424 SSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKAIQEARKMR 483
           SSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKAIQEARKMR
Sbjct: 421 SSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKAIQEARKMR 480

Query: 484 EQIQREQQQQQPHGVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGV 543
           EQIQREQQQQQPHGVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGV
Sbjct: 481 EQIQREQQQQQPHGVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGV 540

Query: 544 IDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNA 603
           IDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNA
Sbjct: 541 IDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNA 600

Query: 604 FMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPN 663
           FMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPN
Sbjct: 601 FMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPN 660

Query: 664 YKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAI 723
           YKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAI
Sbjct: 661 YKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAI 720

Query: 724 TMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMYDDY 783
           TMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMYDDY
Sbjct: 721 TMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMYDDY 780

Query: 784 EDDPKSDYSSENEAPEAVSAN 804
           EDDPKSDYSSENEAPEAVSAN
Sbjct: 781 EDDPKSDYSSENEAPEAVSAN 801


>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
           sapiens]
          Length = 841

 Score = 1540 bits (3987), Expect = 0.0
 Identities = 788/843 (93%), Positives = 788/843 (93%), Gaps = 55/843 (6%)

Query: 3   RMSSKQATSPFACAADGEDAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTL 62
           RMSSKQATSPFACAADGEDAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTL
Sbjct: 13  RMSSKQATSPFACAADGEDAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTL 72

Query: 63  VSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGT 122
           VSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGT
Sbjct: 73  VSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGT 132

Query: 123 PERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKG 182
           PERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKG
Sbjct: 133 PERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKG 192

Query: 183 TPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIAR 242
           TPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIAR
Sbjct: 193 TPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIAR 252

Query: 243 QQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKP 302
           QQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKP
Sbjct: 253 QQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKP 312

Query: 303 GDNYPVQFIPSTMAAAAASGLSPLQLQ--------------------------------- 329
           GDNYPVQFIPSTMAAAAASGLSPLQLQ                                 
Sbjct: 313 GDNYPVQFIPSTMAAAAASGLSPLQLQKGHVSHPQINQRLKGLSDRFGRNLDTFEHGGGH 372

Query: 330 --------QLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPTGIKNEKRGTSPVTQVKDE 381
                   QLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPTGIKNEKRGTSPVTQVKDE
Sbjct: 373 SYNHKQIEQLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPTGIKNEKRGTSPVTQVKDE 432

Query: 382 AAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPSPIGGSLGRGSSLG 441
           AAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPSPIGGSLGRGSSL 
Sbjct: 433 AAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPSPIGGSLGRGSSL- 491

Query: 442 KWKSQHQEETYELDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGK 501
                        DILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGK
Sbjct: 492 -------------DILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGK 538

Query: 502 LSSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGVIDLTRPEDAEGSKAMNGS 561
           LSSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGVIDLTRPEDAEGSKAMNGS
Sbjct: 539 LSSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGVIDLTRPEDAEGSKAMNGS 598

Query: 562 AAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPD 621
           AAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPD
Sbjct: 599 AAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPD 658

Query: 622 MHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKL 681
           MHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKL
Sbjct: 659 MHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKL 718

Query: 682 RIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSST 741
           RIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSST
Sbjct: 719 RIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSST 778

Query: 742 SASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMYDDYEDDPKSDYSSENEAPEAV 801
           SASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMYDDYEDDPKSDYSSENEAPEAV
Sbjct: 779 SASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMYDDYEDDPKSDYSSENEAPEAV 838

Query: 802 SAN 804
           SAN
Sbjct: 839 SAN 841


>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
           sapiens]
          Length = 808

 Score = 1483 bits (3838), Expect = 0.0
 Identities = 767/842 (91%), Positives = 767/842 (91%), Gaps = 75/842 (8%)

Query: 4   MSSKQATSPFACAADGEDAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTLV 63
           MSSKQATSPFACAADGEDAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTLV
Sbjct: 1   MSSKQATSPFACAADGEDAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTLV 60

Query: 64  STIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGTP 123
           STIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGTP
Sbjct: 61  STIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGTP 120

Query: 124 ERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGT 183
           ERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGT
Sbjct: 121 ERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGT 180

Query: 184 PESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQ 243
           PESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQ
Sbjct: 181 PESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQ 240

Query: 244 QQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPG 303
           QQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPG
Sbjct: 241 QQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPG 300

Query: 304 DNYPVQFIPSTMAAAAASGLSPLQLQ---------------------------------- 329
           DNYPVQFIPSTMAAAAASGLSPLQLQ                                  
Sbjct: 301 DNYPVQFIPSTMAAAAASGLSPLQLQKGHVSHPQINQRLKGLSDRFGRNLDTFEHGGGHS 360

Query: 330 -------QLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPTGIKNEKRGTSPVTQVKDEA 382
                  QLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPTGIKNEKRGTSPVTQVKDEA
Sbjct: 361 YNHKQIEQLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPTGIKNEKRGTSPVTQVKDEA 420

Query: 383 AAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPSPIGGSLGRGSSLGK 442
           AAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPSPIGGSLGRGSSL  
Sbjct: 421 AAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPSPIGGSLGRGSSL-- 478

Query: 443 WKSQHQEETYELDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKL 502
                       DILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKL
Sbjct: 479 ------------DILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKL 526

Query: 503 SSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGVIDLTRPEDAEGSKAMNGSA 562
           SSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGVIDLTRPEDAEG        
Sbjct: 527 SSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGVIDLTRPEDAEG-------- 578

Query: 563 AKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDM 622
                       GATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDM
Sbjct: 579 ------------GATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDM 626

Query: 623 HNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLR 682
           HNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLR
Sbjct: 627 HNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLR 686

Query: 683 IGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTS 742
           IGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTS
Sbjct: 687 IGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTS 746

Query: 743 ASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMYDDYEDDPKSDYSSENEAPEAVS 802
           ASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMYDDYEDDPKSDYSSENEAPEAVS
Sbjct: 747 ASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMYDDYEDDPKSDYSSENEAPEAVS 806

Query: 803 AN 804
           AN
Sbjct: 807 AN 808


>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
           sapiens]
          Length = 763

 Score =  845 bits (2184), Expect = 0.0
 Identities = 482/812 (59%), Positives = 572/812 (70%), Gaps = 71/812 (8%)

Query: 3   RMSSKQATSPFACAADGEDAMTQDLTSREK--EEGSDQHVASHLPLHPIMHNKPHSEELP 60
           RMSSK+  SP+   ADGE AM   +TSR+K  EE SD   A HLPLH    NKPHSEE  
Sbjct: 13  RMSSKRPASPYG-EADGEVAM---VTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQ 68

Query: 61  TLVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDR-EIMTSVT 119
            +    Q+     +  S    ME + NK+ S ++  N+STSP K +EG R   E ++S  
Sbjct: 69  PVSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTA 128

Query: 120 FGTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGE 179
            GTPERRKGSLADVVDTLKQ+K+EE+ + E E++  +EKLLSKDWK+K+  + +    GE
Sbjct: 129 LGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNF-GE 187

Query: 180 IKGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQ 239
           IKGTPESLAEKERQL  MI QL SLREQLLAAHDEQKKLAASQIEKQRQQM+LA+QQQEQ
Sbjct: 188 IKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQ 247

Query: 240 IARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGIT 299
           IARQQQQLLQQQHKINLLQQQIQVQG +PPLMIP+FP DQRTLAAAA  QQGFL PPG +
Sbjct: 248 IARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAA--QQGFLLPPGFS 305

Query: 300 YKPG--DNYPVQFIPSTMAAAAAS--GLSPLQLQQLYAAQLASMQVSPGAKMPSTPQPPN 355
           YK G  D YPVQ IP+TMAAAAA+  GL PLQLQQLYAAQLA+MQVSPG K+P  PQ  N
Sbjct: 306 YKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQG-N 364

Query: 356 TAGTVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKT 415
               VSPT I  +K   SP  + KDE A QPLNLS++PKT++  KSPTSPT    PA + 
Sbjct: 365 LGAAVSPTSIHTDKSTNSPPPKSKDEVA-QPLNLSAKPKTSDG-KSPTSPTSPHMPALRI 422

Query: 416 SPVNLPNKSSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKA 475
           +    P K+S+P+ +     R S++G                          D D V KA
Sbjct: 423 NSGAGPLKASVPAALASPSARVSTIG-----------------------YLNDHDAVTKA 459

Query: 476 IQEARKMREQIQREQQQQQPHGVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNE 535
           IQEAR+M+EQ++REQQ      +DGK++ +N++GLN+CR EKE+T  E+L  QL  K NE
Sbjct: 460 IQEARQMKEQLRREQQV-----LDGKVAVVNSLGLNNCRTEKEKTTLESLTQQLAVKQNE 514

Query: 536 DGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEP 595
           +GK    ++D     D++GS                    A V+E+R+YR++RGR S+EP
Sbjct: 515 EGKFSHAMMDFNLSGDSDGS--------------------AGVSESRIYRESRGRGSNEP 554

Query: 596 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 655
           HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWK+M+N EKQPYYEEQARLSK
Sbjct: 555 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 614

Query: 656 IHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGT 715
            HLEKYP+YKYKPRPKRTC+VDGKKLRIGEYK +MR+RRQEMRQ+F VGQQ QIPI T  
Sbjct: 615 QHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIAT-A 673

Query: 716 GVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGN---EMIN 772
           GVVYPGAI MA   PSP + S+ SS S+SPEP +PVIQSTYG+K +   +      E IN
Sbjct: 674 GVVYPGAIAMA-GMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDIN 732

Query: 773 GEDEMEMYDDYEDDPKSDYSSENEAPEAVSAN 804
           GE   E YD+ EDDP  DY S++E   A  AN
Sbjct: 733 GEIYDE-YDEEEDDPDVDYGSDSENHIAGQAN 763


>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
           sapiens]
          Length = 750

 Score =  843 bits (2179), Expect = 0.0
 Identities = 481/811 (59%), Positives = 571/811 (70%), Gaps = 71/811 (8%)

Query: 4   MSSKQATSPFACAADGEDAMTQDLTSREK--EEGSDQHVASHLPLHPIMHNKPHSEELPT 61
           MSSK+  SP+   ADGE AM   +TSR+K  EE SD   A HLPLH    NKPHSEE   
Sbjct: 1   MSSKRPASPYG-EADGEVAM---VTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQP 56

Query: 62  LVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDR-EIMTSVTF 120
           +    Q+     +  S    ME + NK+ S ++  N+STSP K +EG R   E ++S   
Sbjct: 57  VSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTAL 116

Query: 121 GTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEI 180
           GTPERRKGSLADVVDTLKQ+K+EE+ + E E++  +EKLLSKDWK+K+  + +    GEI
Sbjct: 117 GTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNF-GEI 175

Query: 181 KGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQI 240
           KGTPESLAEKERQL  MI QL SLREQLLAAHDEQKKLAASQIEKQRQQM+LA+QQQEQI
Sbjct: 176 KGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQI 235

Query: 241 ARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITY 300
           ARQQQQLLQQQHKINLLQQQIQVQG +PPLMIP+FP DQRTLAAAA  QQGFL PPG +Y
Sbjct: 236 ARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAA--QQGFLLPPGFSY 293

Query: 301 KPG--DNYPVQFIPSTMAAAAAS--GLSPLQLQQLYAAQLASMQVSPGAKMPSTPQPPNT 356
           K G  D YPVQ IP+TMAAAAA+  GL PLQLQQLYAAQLA+MQVSPG K+P  PQ  N 
Sbjct: 294 KAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQG-NL 352

Query: 357 AGTVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTS 416
              VSPT I  +K   SP  + KDE A QPLNLS++PKT++  KSPTSPT    PA + +
Sbjct: 353 GAAVSPTSIHTDKSTNSPPPKSKDEVA-QPLNLSAKPKTSDG-KSPTSPTSPHMPALRIN 410

Query: 417 PVNLPNKSSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKAI 476
               P K+S+P+ +     R S++G                          D D V KAI
Sbjct: 411 SGAGPLKASVPAALASPSARVSTIG-----------------------YLNDHDAVTKAI 447

Query: 477 QEARKMREQIQREQQQQQPHGVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNED 536
           QEAR+M+EQ++REQQ      +DGK++ +N++GLN+CR EKE+T  E+L  QL  K NE+
Sbjct: 448 QEARQMKEQLRREQQV-----LDGKVAVVNSLGLNNCRTEKEKTTLESLTQQLAVKQNEE 502

Query: 537 GKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPH 596
           GK    ++D     D++GS                    A V+E+R+YR++RGR S+EPH
Sbjct: 503 GKFSHAMMDFNLSGDSDGS--------------------AGVSESRIYRESRGRGSNEPH 542

Query: 597 IKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKI 656
           IKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWK+M+N EKQPYYEEQARLSK 
Sbjct: 543 IKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQ 602

Query: 657 HLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTG 716
           HLEKYP+YKYKPRPKRTC+VDGKKLRIGEYK +MR+RRQEMRQ+F VGQQ QIPI T  G
Sbjct: 603 HLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIAT-AG 661

Query: 717 VVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGN---EMING 773
           VVYPGAI MA   PSP + S+ SS S+SPEP +PVIQSTYG+K +   +      E ING
Sbjct: 662 VVYPGAIAMA-GMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDING 720

Query: 774 EDEMEMYDDYEDDPKSDYSSENEAPEAVSAN 804
           E   E YD+ EDDP  DY S++E   A  AN
Sbjct: 721 EIYDE-YDEEEDDPDVDYGSDSENHIAGQAN 750


>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
           sapiens]
          Length = 377

 Score =  422 bits (1086), Expect = e-118
 Identities = 235/427 (55%), Positives = 289/427 (67%), Gaps = 55/427 (12%)

Query: 381 EAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPSPIGGSLGRGSSL 440
           +  AQPLNLS++PKT++  KSPTSPT    PA + +    P K+S+P+ +     R S++
Sbjct: 3   DEVAQPLNLSAKPKTSDG-KSPTSPTSPHMPALRINSGAGPLKASVPAALASPSARVSTI 61

Query: 441 GKWKSQHQEETYELDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDG 500
           G                          D D V KAIQEAR+M+EQ++REQQ      +DG
Sbjct: 62  G-----------------------YLNDHDAVTKAIQEARQMKEQLRREQQV-----LDG 93

Query: 501 KLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGVIDLTRPEDAEGSKAMNG 560
           K++ +N++GLN+CR EKE+T  E+L  QL  K NE+GK    ++D     D++GS     
Sbjct: 94  KVAVVNSLGLNNCRTEKEKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGS----- 148

Query: 561 SAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFP 620
                          A V+E+R+YR++RGR S+EPHIKRPMNAFMVWAKDERRKILQAFP
Sbjct: 149 ---------------AGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFP 193

Query: 621 DMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKK 680
           DMHNSNISKILGSRWK+M+N EKQPYYEEQARLSK HLEKYP+YKYKPRPKRTC+VDGKK
Sbjct: 194 DMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKK 253

Query: 681 LRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSS 740
           LRIGEYK +MR+RRQEMRQ+F VGQQ QIPI T  GVVYPGAI MA   PSP + S+ SS
Sbjct: 254 LRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIAT-AGVVYPGAIAMA-GMPSPHLPSEHSS 311

Query: 741 TSASPEPSLPVIQSTYGMKTDGGSLAGN---EMINGEDEMEMYDDYEDDPKSDYSSENEA 797
            S+SPEP +PVIQSTYG+K +   +      E INGE   E YD+ EDDP  DY S++E 
Sbjct: 312 VSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYDE-YDEEEDDPDVDYGSDSEN 370

Query: 798 PEAVSAN 804
             A  AN
Sbjct: 371 HIAGQAN 377


>gi|41406089 SRY-box 13 [Homo sapiens]
          Length = 622

 Score =  361 bits (927), Expect = 1e-99
 Identities = 260/673 (38%), Positives = 341/673 (50%), Gaps = 143/673 (21%)

Query: 121 GTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEI 180
           G+PE ++  +++     ++K   +  R  +E    +EKLLS DWKE+    N+ E   ++
Sbjct: 82  GSPEPKRPGVSEAASGSQEKL--DFNRNLKEVVPAIEKLLSSDWKERFLGRNSMEAK-DV 138

Query: 181 KGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQI 240
           KGT ESLAEKE QL  MI QL +LR+QLL AH EQK +AA   EKQ+QQM+LARQQQEQI
Sbjct: 139 KGTQESLAEKELQLLVMIHQLSTLRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQI 198

Query: 241 ARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITY 300
           A+QQQQL+QQQHKINLLQQQIQ Q +MP +MIP FP   + L     +Q      P I  
Sbjct: 199 AKQQQQLIQQQHKINLLQQQIQ-QVNMPYVMIPAFPPSHQPLPVTPDSQLALPIQP-IPC 256

Query: 301 KPGDNYPVQFIPSTMAAAAASGLSPLQLQQLYAAQLASMQVSPGAKMPSTPQPPNTAGTV 360
           KP + YP+Q + S  A                          PGA     P         
Sbjct: 257 KPVE-YPLQLLHSPPAPVVKR---------------------PGAMATHHPL-------- 286

Query: 361 SPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNL 420
                               +  +QPLNL+++PK  E   + +SP+             L
Sbjct: 287 --------------------QEPSQPLNLTAKPKAPELPNTSSSPS-------------L 313

Query: 421 PNKSSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKAIQEAR 480
              S +P P                 H   T +L            G+ D V KAIQ+AR
Sbjct: 314 KMSSCVPRP---------------PSHGGPTRDLQSSPPSLPLGFLGEGDAVTKAIQDAR 358

Query: 481 KMREQIQREQQQQQPHGVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLG 540
           ++               +DG  ++     L S  +   + R E            DG + 
Sbjct: 359 QLLHS--------HSGALDGSPNTPFRKDLISLDSSPAKERLE------------DGCVH 398

Query: 541 PGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRP 600
           P        E+A  S  M+GS                    R + ++R  +    HIKRP
Sbjct: 399 P-------LEEAMLSCDMDGS--------------------RHFPESRNSS----HIKRP 427

Query: 601 MNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEK 660
           MNAFMVWAKDERRKILQAFPDMHNS+ISKILGSRWKSM+NQEKQPYYEEQARLS+ HLEK
Sbjct: 428 MNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEK 487

Query: 661 YPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYP 720
           YP+YKYKPRPKRTCIV+GK+LR+GEYK LMR+RRQ+ RQ + +  Q      + + V+YP
Sbjct: 488 YPDYKYKPRPKRTCIVEGKRLRVGEYKALMRTRRQDARQSYVIPPQAGQVQMSSSDVLYP 547

Query: 721 GAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMY 780
            A  M    P  +          S +P++PVI +T  ++ +G        +  + EM  Y
Sbjct: 548 RAAGMPLAQPLVE-----HYVPRSLDPNMPVIVNTCSLREEGEGTDDRHSV-ADGEMYRY 601

Query: 781 ---DDYEDDPKSD 790
              +D E + KSD
Sbjct: 602 SEDEDSEGEEKSD 614


>gi|11967991 SRY-box 17 [Homo sapiens]
          Length = 414

 Score =  109 bits (272), Expect = 1e-23
 Identities = 48/98 (48%), Positives = 68/98 (69%)

Query: 575 GATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSR 634
           G   A +     A GRA  E  I+RPMNAFMVWAKDER+++ Q  PD+HN+ +SK+LG  
Sbjct: 46  GEAPANSGAPAGAAGRAKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKS 105

Query: 635 WKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKR 672
           WK+++  EK+P+ EE  RL   H++ +PNYKY+PR ++
Sbjct: 106 WKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRK 143


>gi|13899269 SRY-box 7 [Homo sapiens]
          Length = 388

 Score =  105 bits (262), Expect = 2e-22
 Identities = 52/119 (43%), Positives = 71/119 (59%), Gaps = 9/119 (7%)

Query: 563 AKLQQYYCWPTGGATVAEARVYRDAR---------GRASSEPHIKRPMNAFMVWAKDERR 613
           A L   Y WP G    A      D +         G   SE  I+RPMNAFMVWAKDER+
Sbjct: 2   ASLLGAYPWPEGLECPALDAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDERK 61

Query: 614 KILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKR 672
           ++    PD+HN+ +SK+LG  WK+++  +K+PY +E  RL   H++ YPNYKY+PR K+
Sbjct: 62  RLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKK 120


>gi|8924248 SRY-box 18 [Homo sapiens]
          Length = 384

 Score =  104 bits (259), Expect = 4e-22
 Identities = 45/83 (54%), Positives = 62/83 (74%)

Query: 590 RASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEE 649
           +A+ E  I+RPMNAFMVWAKDER+++ Q  PD+HN+ +SK+LG  WK ++  EK+P+ EE
Sbjct: 78  QAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEE 137

Query: 650 QARLSKIHLEKYPNYKYKPRPKR 672
             RL   HL  +PNYKY+PR K+
Sbjct: 138 AERLRVQHLRDHPNYKYRPRRKK 160


>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
          Length = 474

 Score =  103 bits (258), Expect = 5e-22
 Identities = 49/100 (49%), Positives = 64/100 (64%)

Query: 572 PTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKIL 631
           PT G+T +      D     +   HIKRPMNAFMVW++ ERRKI++  PDMHN+ ISK L
Sbjct: 34  PTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRL 93

Query: 632 GSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPK 671
           G RWK + + +K P+  E  RL   H+  YP+YKY+PR K
Sbjct: 94  GKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKK 133


>gi|4507161 SRY-box 11 [Homo sapiens]
          Length = 441

 Score =  103 bits (256), Expect = 8e-22
 Identities = 46/76 (60%), Positives = 56/76 (73%)

Query: 596 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 655
           HIKRPMNAFMVW+K ERRKI++  PDMHN+ ISK LG RWK + + EK P+  E  RL  
Sbjct: 48  HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107

Query: 656 IHLEKYPNYKYKPRPK 671
            H+  YP+YKY+PR K
Sbjct: 108 KHMADYPDYKYRPRKK 123


>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
          Length = 391

 Score =  102 bits (253), Expect = 2e-21
 Identities = 44/92 (47%), Positives = 65/92 (70%)

Query: 589 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 648
           G  +++  +KRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK MS  EK+P+ +
Sbjct: 43  GAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFID 102

Query: 649 EQARLSKIHLEKYPNYKYKPRPKRTCIVDGKK 680
           E  RL  +H++++P+YKY+PR K   ++   K
Sbjct: 103 EAKRLRALHMKEHPDYKYRPRRKTKTLLKKDK 134


>gi|4759162 SRY-box 14 [Homo sapiens]
          Length = 240

 Score =  100 bits (250), Expect = 4e-21
 Identities = 44/76 (57%), Positives = 58/76 (76%)

Query: 596 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 655
           HIKRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK +S  EK+PY +E  RL  
Sbjct: 7   HIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRA 66

Query: 656 IHLEKYPNYKYKPRPK 671
            H++++P+YKY+PR K
Sbjct: 67  QHMKEHPDYKYRPRRK 82


>gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]
          Length = 315

 Score =  100 bits (249), Expect = 5e-21
 Identities = 44/76 (57%), Positives = 56/76 (73%)

Query: 596 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 655
           HIKRPMNAFMVW++ ERRKI+  +PDMHN+ ISK LG RW+ + + EK P+  E  RL  
Sbjct: 39  HIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRL 98

Query: 656 IHLEKYPNYKYKPRPK 671
            H+  YP+YKY+PR K
Sbjct: 99  KHMADYPDYKYRPRKK 114


>gi|28195386 sex-determining region Y-box 2 [Homo sapiens]
          Length = 317

 Score =  100 bits (248), Expect = 7e-21
 Identities = 49/108 (45%), Positives = 70/108 (64%), Gaps = 6/108 (5%)

Query: 574 GGATVAEARVYRDARGRASSEP-HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILG 632
           GG + A A     A G   + P  +KRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG
Sbjct: 22  GGNSTAAA-----AGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLG 76

Query: 633 SRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKK 680
           + WK +S  EK+P+ +E  RL  +H++++P+YKY+PR K   ++   K
Sbjct: 77  AEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDK 124


>gi|5902108 SRY-box 21 [Homo sapiens]
          Length = 276

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 41/76 (53%), Positives = 59/76 (77%)

Query: 596 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 655
           H+KRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK ++  EK+P+ +E  RL  
Sbjct: 7   HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66

Query: 656 IHLEKYPNYKYKPRPK 671
           +H++++P+YKY+PR K
Sbjct: 67  MHMKEHPDYKYRPRRK 82


>gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]
          Length = 446

 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 42/92 (45%), Positives = 64/92 (69%)

Query: 589 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 648
           G  + +  +KRPMNAFMVW++ +RRK+    P MHNS ISK LG+ WK +++ EK+P+ +
Sbjct: 131 GGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFID 190

Query: 649 EQARLSKIHLEKYPNYKYKPRPKRTCIVDGKK 680
           E  RL  +H+++YP+YKY+PR K   ++   K
Sbjct: 191 EAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDK 222


>gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]
          Length = 446

 Score = 97.8 bits (242), Expect = 3e-20
 Identities = 40/85 (47%), Positives = 60/85 (70%)

Query: 589 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 648
           G   ++PH+KRPMNAFMVWA+  RRK+   +P +HN+ +SK LG  W+ +S  EK+P+ E
Sbjct: 94  GALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVE 153

Query: 649 EQARLSKIHLEKYPNYKYKPRPKRT 673
           E  RL   H + +P+YKY+PR +++
Sbjct: 154 EAERLRVQHKKDHPDYKYQPRRRKS 178


>gi|4557853 transcription factor SOX9 [Homo sapiens]
          Length = 509

 Score = 97.4 bits (241), Expect = 5e-20
 Identities = 39/85 (45%), Positives = 61/85 (71%)

Query: 589 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 648
           G + ++PH+KRPMNAFMVWA+  RRK+   +P +HN+ +SK LG  W+ ++  EK+P+ E
Sbjct: 97  GSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVE 156

Query: 649 EQARLSKIHLEKYPNYKYKPRPKRT 673
           E  RL   H + +P+YKY+PR +++
Sbjct: 157 EAERLRVQHKKDHPDYKYQPRRRKS 181


>gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]
          Length = 466

 Score = 97.4 bits (241), Expect = 5e-20
 Identities = 39/84 (46%), Positives = 60/84 (71%)

Query: 589 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 648
           G + S+PH+KRPMNAFMVWA+  RRK+   +P +HN+ +SK LG  W+ ++  +K+P+ E
Sbjct: 96  GASKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIE 155

Query: 649 EQARLSKIHLEKYPNYKYKPRPKR 672
           E  RL   H + +P+YKY+PR ++
Sbjct: 156 EAERLRMQHKKDHPDYKYQPRRRK 179


>gi|4507225 sex determining region Y [Homo sapiens]
          Length = 204

 Score = 96.7 bits (239), Expect = 8e-20
 Identities = 41/82 (50%), Positives = 59/82 (71%)

Query: 590 RASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEE 649
           + + +  +KRPMNAF+VW++D+RRK+    P M NS ISK LG +WK ++  EK P+++E
Sbjct: 53  KGNVQDRVKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQE 112

Query: 650 QARLSKIHLEKYPNYKYKPRPK 671
             +L  +H EKYPNYKY+PR K
Sbjct: 113 AQKLQAMHREKYPNYKYRPRRK 134


>gi|5902106 SRY-box 15 [Homo sapiens]
          Length = 233

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 42/75 (56%), Positives = 54/75 (72%)

Query: 597 IKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKI 656
           +KRPMNAFMVW+  +RR++ Q  P MHNS ISK LG++WK +   EK+P+ EE  RL   
Sbjct: 49  VKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRAR 108

Query: 657 HLEKYPNYKYKPRPK 671
           HL  YP+YKY+PR K
Sbjct: 109 HLRDYPDYKYRPRRK 123


>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
           sapiens]
          Length = 753

 Score = 87.8 bits (216), Expect = 4e-17
 Identities = 58/192 (30%), Positives = 94/192 (48%), Gaps = 13/192 (6%)

Query: 596 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 655
           H+KRPMNAFMVWA+  R  + +A P  +N+ IS  LG  W  +S ++K+PYY+E  ++ +
Sbjct: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395

Query: 656 IHLEKYPNYKYKPRP--KRTCIVDGKKLRIGEYKQLMRSRRQEM-----RQFFTVGQQPQ 708
            H E++P + Y+PRP  ++   +    +  G  + ++ +    +       +  V    Q
Sbjct: 396 KHREEFPGWVYQPRPGKRKRFPLSVSNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQ 455

Query: 709 IPITTGTGVVYPG--AITMATTTPSPQMTSDCSSTSAS----PEPSLPVIQSTYGMKTDG 762
            PIT   G   P     T A  +PSP      S +SA+     +PSLPV  +    +  G
Sbjct: 456 NPITHPVGETSPAIQLPTPAVQSPSPVTLFQPSVSSAAQVAVQDPSLPVYPALPPQRFTG 515

Query: 763 GSLAGNEMINGE 774
            S      ++ E
Sbjct: 516 PSQTDTHQLHSE 527


>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
           sapiens]
          Length = 501

 Score = 83.2 bits (204), Expect = 9e-16
 Identities = 34/75 (45%), Positives = 52/75 (69%)

Query: 596 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 655
           H+KRPMNAFMVWA+  R  + +A P  +N+ IS  LG  W  +S ++K+PYY+E  ++ +
Sbjct: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395

Query: 656 IHLEKYPNYKYKPRP 670
            H E++P + Y+PRP
Sbjct: 396 KHREEFPGWVYQPRP 410


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 29/89 (32%), Positives = 54/89 (60%)

Query: 596 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 655
           HI+RPMNAFM+++K  R  + Q  P+  N  +SKILG  W ++  +EKQ Y++   ++ +
Sbjct: 199 HIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKE 258

Query: 656 IHLEKYPNYKYKPRPKRTCIVDGKKLRIG 684
            H + +P++K+  + ++    + K   +G
Sbjct: 259 AHFKAHPDWKWCNKDRKKSSSEAKPTSLG 287



 Score = 31.2 bits (69), Expect = 4.0
 Identities = 51/187 (27%), Positives = 69/187 (36%), Gaps = 30/187 (16%)

Query: 262  QVQGHMP--PLMIPIFPHDQRTLAAAAAAQQG--------FLFPPGITYK--------PG 303
            QVQ  +P  P  + + P         AAA  G        F  PPG +          P 
Sbjct: 824  QVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPT 883

Query: 304  DNYPV-QFIPSTMAAAAASGLSPLQLQQLY-AAQLASMQVSPGAKMPSTPQPPNTAGTVS 361
               P+ Q +PS     A S +SP+Q      +AQL   +V      PS       AG   
Sbjct: 884  PGIPILQSVPSAPPPKAQS-VSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPL 942

Query: 362  PTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLP 421
            P          SP   V  +  AQP +   +  T  PV +P+     L PA+   P + P
Sbjct: 943  PL--------VSPPFSVPVQNGAQPPSKIIQ-LTPVPVSTPSGLVPPLSPATLPGPTSQP 993

Query: 422  NKSSIPS 428
             K  +PS
Sbjct: 994  QKVLLPS 1000


>gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens]
          Length = 602

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 31/85 (36%), Positives = 53/85 (62%), Gaps = 6/85 (7%)

Query: 594 EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARL 653
           +PHIK+P+NAFM++ K+ R K++       ++ I++ILG RW ++S +E+  YYE   + 
Sbjct: 347 KPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKE 406

Query: 654 SKIHLEKYP------NYKYKPRPKR 672
            ++H++ YP      NY  K + KR
Sbjct: 407 RQLHMQLYPGWSARDNYGKKKKRKR 431


>gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens]
          Length = 596

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 31/85 (36%), Positives = 53/85 (62%), Gaps = 6/85 (7%)

Query: 594 EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARL 653
           +PHIK+P+NAFM++ K+ R K++       ++ I++ILG RW ++S +E+  YYE   + 
Sbjct: 324 KPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKE 383

Query: 654 SKIHLEKYP------NYKYKPRPKR 672
            ++H++ YP      NY  K + KR
Sbjct: 384 RQLHMQLYPGWSARDNYGKKKKRKR 408


>gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens]
          Length = 442

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 31/85 (36%), Positives = 53/85 (62%), Gaps = 6/85 (7%)

Query: 594 EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARL 653
           +PHIK+P+NAFM++ K+ R K++       ++ I++ILG RW ++S +E+  YYE   + 
Sbjct: 324 KPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKE 383

Query: 654 SKIHLEKYP------NYKYKPRPKR 672
            ++H++ YP      NY  K + KR
Sbjct: 384 RQLHMQLYPGWSARDNYGKKKKRKR 408


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.125    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,190,168
Number of Sequences: 37866
Number of extensions: 1693025
Number of successful extensions: 16161
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 286
Number of HSP's successfully gapped in prelim test: 721
Number of HSP's that attempted gapping in prelim test: 9050
Number of HSP's gapped (non-prelim): 4772
length of query: 804
length of database: 18,247,518
effective HSP length: 110
effective length of query: 694
effective length of database: 14,082,258
effective search space: 9773087052
effective search space used: 9773087052
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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