BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|13899269 SRY-box 7 [Homo sapiens] (388 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|13899269 SRY-box 7 [Homo sapiens] 815 0.0 gi|11967991 SRY-box 17 [Homo sapiens] 230 1e-60 gi|8924248 SRY-box 18 [Homo sapiens] 222 4e-58 gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens] 129 3e-30 gi|4557853 transcription factor SOX9 [Homo sapiens] 121 1e-27 gi|4507161 SRY-box 11 [Homo sapiens] 120 3e-27 gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens] 119 4e-27 gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens] 119 4e-27 gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 119 5e-27 gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens] 119 5e-27 gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens] 117 2e-26 gi|5902106 SRY-box 15 [Homo sapiens] 117 2e-26 gi|28195386 sex-determining region Y-box 2 [Homo sapiens] 116 3e-26 gi|4759162 SRY-box 14 [Homo sapiens] 116 3e-26 gi|5902108 SRY-box 21 [Homo sapiens] 112 6e-25 gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo... 109 4e-24 gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo... 109 4e-24 gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo... 109 4e-24 gi|4507225 sex determining region Y [Homo sapiens] 106 3e-23 gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 105 7e-23 gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 105 7e-23 gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 105 7e-23 gi|41406089 SRY-box 13 [Homo sapiens] 105 7e-23 gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 104 1e-22 gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo... 92 8e-19 gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom... 92 8e-19 gi|112421108 capicua homolog [Homo sapiens] 64 2e-10 gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo sa... 62 1e-09 gi|18378731 HMG-BOX transcription factor BBX isoform 2 [Homo sap... 62 1e-09 gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens] 57 4e-08 >gi|13899269 SRY-box 7 [Homo sapiens] Length = 388 Score = 815 bits (2106), Expect = 0.0 Identities = 388/388 (100%), Positives = 388/388 (100%) Query: 1 MASLLGAYPWPEGLECPALDAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDER 60 MASLLGAYPWPEGLECPALDAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDER Sbjct: 1 MASLLGAYPWPEGLECPALDAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDER 60 Query: 61 KRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKK 120 KRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKK Sbjct: 61 KRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKK 120 Query: 121 QAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHE 180 QAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHE Sbjct: 121 QAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHE 180 Query: 181 GPAGGGGGGTPSSVDTYPYGLPTPPEMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHLPGH 240 GPAGGGGGGTPSSVDTYPYGLPTPPEMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHLPGH Sbjct: 181 GPAGGGGGGTPSSVDTYPYGLPTPPEMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHLPGH 240 Query: 241 PYSPEYAPSPLHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHL 300 PYSPEYAPSPLHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHL Sbjct: 241 PYSPEYAPSPLHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHL 300 Query: 301 GQLSPPPEHPGFDALDQLSQVELLGDMDRNEFDQYLNTPGHPDSATGAMALSGHVPVSQV 360 GQLSPPPEHPGFDALDQLSQVELLGDMDRNEFDQYLNTPGHPDSATGAMALSGHVPVSQV Sbjct: 301 GQLSPPPEHPGFDALDQLSQVELLGDMDRNEFDQYLNTPGHPDSATGAMALSGHVPVSQV 360 Query: 361 TPTGPTETSLISVLADATATYYNSYSVS 388 TPTGPTETSLISVLADATATYYNSYSVS Sbjct: 361 TPTGPTETSLISVLADATATYYNSYSVS 388 >gi|11967991 SRY-box 17 [Homo sapiens] Length = 414 Score = 230 bits (587), Expect = 1e-60 Identities = 173/415 (41%), Positives = 217/415 (52%), Gaps = 64/415 (15%) Query: 5 LGAYPWPEGLECPALDAELSDGQSPPAVPRPPGDKG---SESRIRRPMNAFMVWAKDERK 61 LG PW E L P D ++ G++P P G G ESRIRRPMNAFMVWAKDERK Sbjct: 27 LGPCPWAESLS-PIGDMKVK-GEAPANSGAPAGAAGRAKGESRIRRPMNAFMVWAKDERK 84 Query: 62 RLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQ 121 RLA QNPDLHNAELSKMLGKSWKALTL++KRP+V+EAERLR+QHMQD+PNYKYRPRR+KQ Sbjct: 85 RLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQ 144 Query: 122 AKRLCKRVDPGFLLSSLSRDQNAL-PEKRSGSRGALGEKEDRGEYSPGTAL--PSLRGCY 178 KRL KRV+ GFL AL PE + LG + + G L P + G Y Sbjct: 145 VKRL-KRVEGGFLHGLAEPQAAALGPEGGRVAMDGLGLQFPEQGFPAGPPLLPPHMGGHY 203 Query: 179 HEGPAGGGGGGTPSSVDTYPYGLPTPPEMSPLDVLEPEQTFFSSPCQ------------- 225 + + G +D YP LPT P+ SPLD ++P+ FF++P Sbjct: 204 RDCQSLGA-----PPLDGYP--LPT-PDTSPLDGVDPDPAFFAAPMPGDCPAAGTYSYAQ 255 Query: 226 -EEHGHPRRIPHLPGHP-YSPEYA----------PSPLHCSH-PLGSLALGQSPGVSMMS 272 ++ P P P HP PE A PS LH + +GS G G M Sbjct: 256 VSDYAGPPEPPAGPMHPRLGPEPAGPSIPGLLAPPSALHVYYGAMGSPGAGGGRGFQMQ- 314 Query: 273 PVPGCPPSPAYYSPATYHPLHSNLQAHLGQLSPPPEH-PGFDALDQLSQVELLGDMDRNE 331 P + +HP GQ SPPPE P D D ELLG++DR E Sbjct: 315 ------PQHQHQHQHQHHP------PGPGQPSPPPEALPCRDGTDPSQPAELLGEVDRTE 362 Query: 332 FDQYLNTPGHPDSATGAMALSGHVPVSQVTPTGPTETSLISVLADA-TATYYNSY 385 F+QYL+ P+ + GH + ++ SV++DA +A YY +Y Sbjct: 363 FEQYLHFVCKPEM---GLPYQGH---DSGVNLPDSHGAISSVVSDASSAVYYCNY 411 >gi|8924248 SRY-box 18 [Homo sapiens] Length = 384 Score = 222 bits (566), Expect = 4e-58 Identities = 171/411 (41%), Positives = 209/411 (50%), Gaps = 81/411 (19%) Query: 2 ASLLGAYPWPEGLECPALDAELSDGQ-SPPAVPRP------PGDKGS-----ESRIRRPM 49 A G P L PA A Q SPP P P P +G ESRIRRPM Sbjct: 30 ADTRGLAAGPAALAAPAAPASPPSPQRSPPRSPEPGRYGLSPAGRGERQAADESRIRRPM 89 Query: 50 NAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDY 109 NAFMVWAKDERKRLA QNPDLHNA LSKMLGK+WK L ++KRP+V+EAERLR+QH++D+ Sbjct: 90 NAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDH 149 Query: 110 PNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNALPE---KRSGSRGALGEKEDRGEYS 166 PNYKYRPRRKKQA++ +R++PG LL L+ Q PE SGS A E Sbjct: 150 PNYKYRPRRKKQARK-ARRLEPGLLLPGLAPPQPP-PEPFPAASGSARAFRE-------- 199 Query: 167 PGTALPSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTPPEMSPLDVLEP-EQTFFSSPCQ 225 LP L G +G GLPT PE SPLD LEP E FF P Sbjct: 200 ----LPPL-GAEFDG-----------------LGLPT-PERSPLDGLEPGEAAFFPPPAA 236 Query: 226 EEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYY- 284 E R P+ YAP+ L P G G ++ + P P + YY Sbjct: 237 PEDCALR--------PFRAPYAPTEL-SRDPGG--CYGAPLAEALRTAPPAAPLAGLYYG 285 Query: 285 ---SPATYHPLHSNLQAHLGQLSPPPEHPGFDALDQLS-QVELLGDMDRNEFDQYLNTPG 340 +P Y G LSPPPE P ++ + L +L D+D EFDQYLN Sbjct: 286 TLGTPGPYP----------GPLSPPPEAPPLESAEPLGPAADLWADVDLTEFDQYLNCSR 335 Query: 341 HPDSATGAMALSGHVPVSQVTPTG---PTETSLISVLADATATYYNSYSVS 388 A G L HV ++++ P P E+SLIS L+DA++ Y S +S Sbjct: 336 TRPDAPG---LPYHVALAKLGPRAMSCPEESSLISALSDASSAVYYSACIS 383 >gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens] Length = 391 Score = 129 bits (325), Expect = 3e-30 Identities = 90/271 (33%), Positives = 136/271 (50%), Gaps = 31/271 (11%) Query: 37 GDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVD 96 G K ++ R++RPMNAFMVW++ +R+++A +NP +HN+E+SK LG WK ++ ++KRP++D Sbjct: 43 GAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFID 102 Query: 97 EAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGAL 156 EA+RLR HM+++P+YKYRPRRK K L K+ SL+ A G+ A+ Sbjct: 103 EAKRLRALHMKEHPDYKYRPRRK--TKTLLKKDK-----YSLAGGLLAAGAGGGGAAVAM 155 Query: 157 GEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPS----SVDTYPYGLPTPPEMSPLDV 212 G G + G L E P G GGG + YP + + + + Sbjct: 156 GVGVGVGAAAVGQRL--------ESPGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAM-M 206 Query: 213 LEPEQTFFSSP---CQEEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGSL---ALGQSP 266 E + + P H HP PH P HP++ + P P+H + +G+L + S Sbjct: 207 QEAQLAYGQHPGAGGAHPHAHPAH-PH-PHHPHAHPHNPQPMH-RYDMGALQYSPISNSQ 263 Query: 267 GVSMMSP--VPGCPPSPAYYSPATYHPLHSN 295 G SP G P A + A H N Sbjct: 264 GYMSASPSGYGGLPYGAAAAAAAAAGGAHQN 294 >gi|4557853 transcription factor SOX9 [Homo sapiens] Length = 509 Score = 121 bits (303), Expect = 1e-27 Identities = 103/335 (30%), Positives = 140/335 (41%), Gaps = 41/335 (12%) Query: 30 PAVPRPPGDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLS 89 P R G ++ ++RPMNAFMVWA+ R++LA Q P LHNAELSK LGK W+ L S Sbjct: 90 PMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNES 149 Query: 90 QKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQ--NALPE 147 +KRP+V+EAERLR+QH +D+P+YKY+PRR+K K + + +S + AL Sbjct: 150 EKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKNGQAEAEEATEQTHISPNAIFKALQA 209 Query: 148 KRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTPP-- 205 S + E GE+S + P + G P G PP Sbjct: 210 DSPHSSSGMSEVHSPGEHSGQSQGPPTPPTTPKTDVQPGKADLKREGRPLPEGGRQPPID 269 Query: 206 -------EMSPLDVLEPEQTFFSSPCQE---EHGHPRRIPHLPGH-PYSPEY-----APS 249 E+S DV+ +TF + + +GHP +P G Y+ Y A + Sbjct: 270 FRDVDIGELSS-DVISNIETFDVNEFDQYLPPNGHP-GVPATHGQVTYTGSYGISSTAAT 327 Query: 250 PLHCSHPLGSLALGQSPGVS---MMSPVPGCPPSPAYYSPATYHPLHSNLQAHLGQLSPP 306 P H S P P P PP P P Q + P Sbjct: 328 PASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPPQPQAAPPQ--------------QPAAP 373 Query: 307 PEHPGFDALDQLSQVELLGDMDRNEFDQYLNTPGH 341 P+ P L LS G R +P H Sbjct: 374 PQQPQAHTLTTLSSEP--GQSQRTHIKTEQLSPSH 406 Score = 30.8 bits (68), Expect = 2.2 Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 8/94 (8%) Query: 278 PPSPAYYSPATYHPLHSNLQAHLGQLSPPPEHPGFDALD----QLSQ--VELLGDMDRNE 331 PP+P P ++L+ L P D D +LS + + D NE Sbjct: 234 PPTPPTTPKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNE 293 Query: 332 FDQYLNTPGHP--DSATGAMALSGHVPVSQVTPT 363 FDQYL GHP + G + +G +S T Sbjct: 294 FDQYLPPNGHPGVPATHGQVTYTGSYGISSTAAT 327 >gi|4507161 SRY-box 11 [Homo sapiens] Length = 441 Score = 120 bits (300), Expect = 3e-27 Identities = 74/180 (41%), Positives = 96/180 (53%), Gaps = 41/180 (22%) Query: 18 ALDAELSDGQ--SPPAVPRPPGD--KGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNA 73 ALD E + SP A+ D K + I+RPMNAFMVW+K ER+++ Q+PD+HNA Sbjct: 18 ALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNA 77 Query: 74 ELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGF 133 E+SK LGK WK L S+K P++ EAERLRL+HM DYP+YKYRPR+K ++DP Sbjct: 78 EISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRPRKKP-------KMDP-- 128 Query: 134 LLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSS 193 S + PEK + G G AGGG GG +S Sbjct: 129 ---SAKPSASQSPEKSAAGGGG-------------------------GSAGGGAGGAKTS 160 >gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens] Length = 466 Score = 119 bits (299), Expect = 4e-27 Identities = 105/322 (32%), Positives = 143/322 (44%), Gaps = 41/322 (12%) Query: 30 PAVPRPPGDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLS 89 P R G S+ ++RPMNAFMVWA+ R++LA Q P LHNAELSK LGK W+ L S Sbjct: 89 PMPVRVNGASKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNES 148 Query: 90 QKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRL-----CK--RVDPGFLLSSLSRDQ 142 KRP+++EAERLR+QH +D+P+YKY+PRR+K K C + G + + + Sbjct: 149 DKRPFIEEAERLRMQHKKDHPDYKYQPRRRKNGKAAQGEAECPGGEAEQGGTAAIQAHYK 208 Query: 143 NALPEKR---SGSRGALGEKEDRGEYS---------PGTALPSLRGCYHEGPAGGGGGGT 190 +A + R GS + G E S P T L S + G GG Sbjct: 209 SAHLDHRHPGEGSPMSDGNPEHPSGQSHGPPTPPTTPKTELQSGKADPKRDGRSMGEGGK 268 Query: 191 P----SSVDTYPYGLPTPPEMSPLDVLEPEQTFFSSPCQEEHGHPRRIP--HLPGHPYSP 244 P +VD M DV E +Q +GHP + G+ Sbjct: 269 PHIDFGNVDIGEISHEVMSNMETFDVAELDQYL------PPNGHPGHVSSYSAAGYGLGS 322 Query: 245 EYAPSPLH---CSHPLG-SLALGQSPGVSMMSPV---PGCPPSPAYYS--PATYHPLHSN 295 A + H S P G +L PGV + V P P +Y+ P+T +++ Sbjct: 323 ALAVASGHSAWISKPPGVALPTVSPPGVDAKAQVKTETAGPQGPPHYTDQPSTSQIAYTS 382 Query: 296 LQ-AHLGQLSPPPEHPGFDALD 316 L H G P P FD D Sbjct: 383 LSLPHYGSAFPSISRPQFDYSD 404 >gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens] Length = 315 Score = 119 bits (299), Expect = 4e-27 Identities = 72/179 (40%), Positives = 88/179 (49%), Gaps = 32/179 (17%) Query: 25 DGQSPPAVPRPPGDKGSE--------SRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELS 76 DG PP P P + E I+RPMNAFMVW++ ER+++ Q PD+HNAE+S Sbjct: 12 DGGPPPPGPGPAEEGAREPGWCKTPSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEIS 71 Query: 77 KMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLS 136 K LG+ W+ L S+K P+V EAERLRL+HM DYP+YKYRPR+K Sbjct: 72 KRLGRRWQLLQDSEKIPFVREAERLRLKHMADYPDYKYRPRKK----------------- 114 Query: 137 SLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVD 195 S A P GS G PG LP G G GGG P D Sbjct: 115 SKGAPAKARPRPPGGSGGG-------SRLKPGPQLPGRGGRRAAGGPLGGGAAAPEDDD 166 >gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] Length = 474 Score = 119 bits (298), Expect = 5e-27 Identities = 70/164 (42%), Positives = 90/164 (54%), Gaps = 19/164 (11%) Query: 35 PPGDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPY 94 P K I+RPMNAFMVW++ ER+++ Q+PD+HNAE+SK LGK WK L S K P+ Sbjct: 49 PSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPF 108 Query: 95 VDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRG 154 + EAERLRL+HM DYP+YKYRPR K+V G SS S ++ P Sbjct: 109 IREAERLRLKHMADYPDYKYRPR---------KKVKSGNANSSSSAAASSKP-------- 151 Query: 155 ALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYP 198 GEK D+ S G G GGGGG + ++ P Sbjct: 152 --GEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKP 193 >gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens] Length = 446 Score = 119 bits (298), Expect = 5e-27 Identities = 105/344 (30%), Positives = 147/344 (42%), Gaps = 81/344 (23%) Query: 37 GDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVD 96 G + R++RPMNAFMVW++ +R+++A++NP +HN+E+SK LG WK LT ++KRP++D Sbjct: 131 GGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFID 190 Query: 97 EAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGAL 156 EA+RLR HM++YP+YKYRPRRK + + L +D+ +LP Sbjct: 191 EAKRLRAVHMKEYPDYKYRPRRKTK--------------TLLKKDKYSLPS--------- 227 Query: 157 GEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYPY----------------G 200 G PG A + A G +DTY + G Sbjct: 228 ------GLLPPGAAAAAAAAA-AAAAAASSPVGVGQRLDTYTHVNGWANGAYSLVQEQLG 280 Query: 201 LPTPPEMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGSL 260 PP M SSP P + G YSP P S+ + Sbjct: 281 YAQPPSM-------------SSPPPPPALPPMHRYDMAGLQYSPMMPPGAQ--SYMNVAA 325 Query: 261 ALGQSPGVSMMSPVPGCPPSPAY-YSPATYHPLHSNLQA-HLGQL---------SPPPEH 309 A + G M+P + AY PAT + A LG + SPPP Sbjct: 326 AAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPP-- 383 Query: 310 PGFDALDQLSQVELLGDMDRNEFDQYLNTPGHPDSATGAMALSG 353 A+ SQ LGD+ R+ YL P D+A A L G Sbjct: 384 ----AIASHSQRACLGDL-RDMISMYL--PPGGDAADAASPLPG 420 >gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens] Length = 446 Score = 117 bits (293), Expect = 2e-26 Identities = 52/83 (62%), Positives = 70/83 (84%) Query: 41 SESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAER 100 ++ ++RPMNAFMVWA+ R++LA Q P LHNAELSK LGK W+ L+ S+KRP+V+EAER Sbjct: 98 AKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAER 157 Query: 101 LRLQHMQDYPNYKYRPRRKKQAK 123 LR+QH +D+P+YKY+PRR+K AK Sbjct: 158 LRVQHKKDHPDYKYQPRRRKSAK 180 >gi|5902106 SRY-box 15 [Homo sapiens] Length = 233 Score = 117 bits (293), Expect = 2e-26 Identities = 88/258 (34%), Positives = 117/258 (45%), Gaps = 55/258 (21%) Query: 14 LECPALDAELSDGQSPP-----AVPRPPGDKGSESRIRRPMNAFMVWAKDERKRLAVQNP 68 LE PA A S P P PG E +++RPMNAFMVW+ +R+++A QNP Sbjct: 14 LEPPAATAAASSSSGPQEREGAGSPAAPGTLPLE-KVKRPMNAFMVWSSAQRRQMAQQNP 72 Query: 69 DLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKR 128 +HN+E+SK LG WK L +KRP+V+EA+RLR +H++DYP+YKYRPRRK Sbjct: 73 KMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKYRPRRK--------- 123 Query: 129 VDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGG 188 ++ A P + RG L + PG A P+ G G Sbjct: 124 ----------AKSSGAGPSRCGQGRGNLASGGPL--WGPGYATTQ--------PSRGFGY 163 Query: 189 GTPSSVDTYPYGLPTPPEMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHL---------PG 239 PS Y LP S + P SPC PR L PG Sbjct: 164 RPPSYSTAY---LPGSYGSSHCKLEAP------SPCSLPQSDPRLQGELLPTYTHYLPPG 214 Query: 240 H--PYSPEYAPSPLHCSH 255 PY+P A +P+ +H Sbjct: 215 SPTPYNPPLAGAPMPLTH 232 >gi|28195386 sex-determining region Y-box 2 [Homo sapiens] Length = 317 Score = 116 bits (291), Expect = 3e-26 Identities = 54/112 (48%), Positives = 79/112 (70%), Gaps = 1/112 (0%) Query: 26 GQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKA 85 G + A K S R++RPMNAFMVW++ +R+++A +NP +HN+E+SK LG WK Sbjct: 22 GGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKL 81 Query: 86 LTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRK-KQAKRLCKRVDPGFLLS 136 L+ ++KRP++DEA+RLR HM+++P+YKYRPRRK K + K PG LL+ Sbjct: 82 LSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLA 133 >gi|4759162 SRY-box 14 [Homo sapiens] Length = 240 Score = 116 bits (291), Expect = 3e-26 Identities = 77/203 (37%), Positives = 105/203 (51%), Gaps = 19/203 (9%) Query: 45 IRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQ 104 I+RPMNAFMVW++ +R+++A +NP +HN+E+SK LG WK L+ ++KRPY+DEA+RLR Q Sbjct: 8 IKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQ 67 Query: 105 HMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNALPEKRSG-----SRGALGEK 159 HM+++P+YKYRPRRK K L K+ F L L + P K +G S G L Sbjct: 68 HMKEHPDYKYRPRRK--PKNLLKKDRYVFPLPYLG---DTDPLKAAGLPVGASDGLLSAP 122 Query: 160 EDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTP--PEMSPLDVLEPEQ 217 E + P + P Y + P+ L T P S L Sbjct: 123 EKARAFLPPASAP-----YSLLDPAQFSSSAIQKMGEVPHTLATGALPYASTLGYQNGAF 177 Query: 218 TFFSSPCQEEHGHPRRIPHLPGH 240 S P Q H HP P PG+ Sbjct: 178 GSLSCPSQHTHTHPS--PTNPGY 198 >gi|5902108 SRY-box 21 [Homo sapiens] Length = 276 Score = 112 bits (280), Expect = 6e-25 Identities = 45/75 (60%), Positives = 65/75 (86%) Query: 45 IRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQ 104 ++RPMNAFMVW++ +R+++A +NP +HN+E+SK LG WK LT S+KRP++DEA+RLR Sbjct: 8 VKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAM 67 Query: 105 HMQDYPNYKYRPRRK 119 HM+++P+YKYRPRRK Sbjct: 68 HMKEHPDYKYRPRRK 82 >gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo sapiens] Length = 377 Score = 109 bits (273), Expect = 4e-24 Identities = 51/102 (50%), Positives = 72/102 (70%), Gaps = 1/102 (0%) Query: 20 DAELSDGQSPPAVPRPPGDKGS-ESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKM 78 D++ S G S + R +GS E I+RPMNAFMVWAKDER+++ PD+HN+ +SK+ Sbjct: 144 DSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKI 203 Query: 79 LGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKK 120 LG WKA+T +K+PY +E RL QH++ YP+YKY+PR K+ Sbjct: 204 LGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKR 245 >gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo sapiens] Length = 750 Score = 109 bits (273), Expect = 4e-24 Identities = 51/102 (50%), Positives = 72/102 (70%), Gaps = 1/102 (0%) Query: 20 DAELSDGQSPPAVPRPPGDKGS-ESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKM 78 D++ S G S + R +GS E I+RPMNAFMVWAKDER+++ PD+HN+ +SK+ Sbjct: 517 DSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKI 576 Query: 79 LGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKK 120 LG WKA+T +K+PY +E RL QH++ YP+YKY+PR K+ Sbjct: 577 LGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKR 618 >gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo sapiens] Length = 763 Score = 109 bits (273), Expect = 4e-24 Identities = 51/102 (50%), Positives = 72/102 (70%), Gaps = 1/102 (0%) Query: 20 DAELSDGQSPPAVPRPPGDKGS-ESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKM 78 D++ S G S + R +GS E I+RPMNAFMVWAKDER+++ PD+HN+ +SK+ Sbjct: 530 DSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKI 589 Query: 79 LGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKK 120 LG WKA+T +K+PY +E RL QH++ YP+YKY+PR K+ Sbjct: 590 LGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKR 631 >gi|4507225 sex determining region Y [Homo sapiens] Length = 204 Score = 106 bits (265), Expect = 3e-23 Identities = 51/109 (46%), Positives = 75/109 (68%), Gaps = 7/109 (6%) Query: 42 ESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERL 101 + R++RPMNAF+VW++D+R+++A++NP + N+E+SK LG WK LT ++K P+ EA++L Sbjct: 57 QDRVKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQEAQKL 116 Query: 102 RLQHMQDYPNYKYRPRRKKQAKRLCKR-----VDPGFLLSSLSRDQNAL 145 + H + YPNYKYRPRRK AK L K DP +L S + N L Sbjct: 117 QAMHREKYPNYKYRPRRK--AKMLPKNCSLLPADPASVLCSEVQLDNRL 163 >gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo sapiens] Length = 841 Score = 105 bits (262), Expect = 7e-23 Identities = 52/119 (43%), Positives = 71/119 (59%), Gaps = 9/119 (7%) Query: 2 ASLLGAYPWPEGLECPALDAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDERK 61 A L Y WP G A D + G SE I+RPMNAFMVWAKDER+ Sbjct: 600 AKLQQYYCWPTGGATVAEARVYRDAR---------GRASSEPHIKRPMNAFMVWAKDERR 650 Query: 62 RLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKK 120 ++ PD+HN+ +SK+LG WK+++ +K+PY +E RL H++ YPNYKY+PR K+ Sbjct: 651 KILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKR 709 >gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo sapiens] Length = 801 Score = 105 bits (262), Expect = 7e-23 Identities = 52/119 (43%), Positives = 71/119 (59%), Gaps = 9/119 (7%) Query: 2 ASLLGAYPWPEGLECPALDAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDERK 61 A L Y WP G A D + G SE I+RPMNAFMVWAKDER+ Sbjct: 560 AKLQQYYCWPTGGATVAEARVYRDAR---------GRASSEPHIKRPMNAFMVWAKDERR 610 Query: 62 RLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKK 120 ++ PD+HN+ +SK+LG WK+++ +K+PY +E RL H++ YPNYKY+PR K+ Sbjct: 611 KILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKR 669 >gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo sapiens] Length = 804 Score = 105 bits (262), Expect = 7e-23 Identities = 52/119 (43%), Positives = 71/119 (59%), Gaps = 9/119 (7%) Query: 2 ASLLGAYPWPEGLECPALDAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDERK 61 A L Y WP G A D + G SE I+RPMNAFMVWAKDER+ Sbjct: 563 AKLQQYYCWPTGGATVAEARVYRDAR---------GRASSEPHIKRPMNAFMVWAKDERR 613 Query: 62 RLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKK 120 ++ PD+HN+ +SK+LG WK+++ +K+PY +E RL H++ YPNYKY+PR K+ Sbjct: 614 KILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKR 672 >gi|41406089 SRY-box 13 [Homo sapiens] Length = 622 Score = 105 bits (262), Expect = 7e-23 Identities = 46/89 (51%), Positives = 66/89 (74%), Gaps = 4/89 (4%) Query: 41 SESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAER 100 + S I+RPMNAFMVWAKDER+++ PD+HN+ +SK+LG WK++T +K+PY +E R Sbjct: 420 NSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQAR 479 Query: 101 LRLQHMQDYPNYKYRPRRKK----QAKRL 125 L QH++ YP+YKY+PR K+ + KRL Sbjct: 480 LSRQHLEKYPDYKYKPRPKRTCIVEGKRL 508 >gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo sapiens] Length = 808 Score = 104 bits (260), Expect = 1e-22 Identities = 44/84 (52%), Positives = 62/84 (73%) Query: 37 GDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVD 96 G SE I+RPMNAFMVWAKDER+++ PD+HN+ +SK+LG WK+++ +K+PY + Sbjct: 593 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 652 Query: 97 EAERLRLQHMQDYPNYKYRPRRKK 120 E RL H++ YPNYKY+PR K+ Sbjct: 653 EQARLSKIHLEKYPNYKYKPRPKR 676 >gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo sapiens] Length = 501 Score = 92.0 bits (227), Expect = 8e-19 Identities = 42/104 (40%), Positives = 63/104 (60%) Query: 20 DAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKML 79 D L+ S +P P K ++RPMNAFMVWA+ R LA NP +NAE+S L Sbjct: 312 DVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQL 371 Query: 80 GKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAK 123 G W L+ QK+PY DEA++++ +H +++P + Y+PR K+ + Sbjct: 372 GLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKR 415 >gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo sapiens] Length = 753 Score = 92.0 bits (227), Expect = 8e-19 Identities = 42/104 (40%), Positives = 63/104 (60%) Query: 20 DAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKML 79 D L+ S +P P K ++RPMNAFMVWA+ R LA NP +NAE+S L Sbjct: 312 DVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQL 371 Query: 80 GKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAK 123 G W L+ QK+PY DEA++++ +H +++P + Y+PR K+ + Sbjct: 372 GLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKR 415 >gi|112421108 capicua homolog [Homo sapiens] Length = 1608 Score = 63.9 bits (154), Expect = 2e-10 Identities = 42/149 (28%), Positives = 76/149 (51%), Gaps = 10/149 (6%) Query: 25 DGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWK 84 DG+SP +K + IRRPMNAFM+++K R + ++P+ N +SK+LG+ W Sbjct: 188 DGRSP--------NKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWY 239 Query: 85 ALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNA 144 AL +K+ Y D A +++ H + +P++K+ + +K++ K G + + Sbjct: 240 ALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERS 299 Query: 145 LPEKRSGSRGALGEKEDRGEYSPGTALPS 173 + E +G+ A G + + T L S Sbjct: 300 MSE--TGTAAAPGVSSELLSVAAQTLLSS 326 >gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo sapiens] Length = 941 Score = 61.6 bits (148), Expect = 1e-09 Identities = 32/94 (34%), Positives = 48/94 (51%) Query: 38 DKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDE 97 D+ E R RRPMNAF+++ K R + ++P L N +K+L W L +K+ Y D Sbjct: 73 DESPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDM 132 Query: 98 AERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDP 131 A+ + M+ P YK+ P K K V+P Sbjct: 133 AKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNP 166 >gi|18378731 HMG-BOX transcription factor BBX isoform 2 [Homo sapiens] Length = 911 Score = 61.6 bits (148), Expect = 1e-09 Identities = 32/94 (34%), Positives = 48/94 (51%) Query: 38 DKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDE 97 D+ E R RRPMNAF+++ K R + ++P L N +K+L W L +K+ Y D Sbjct: 73 DESPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDM 132 Query: 98 AERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDP 131 A+ + M+ P YK+ P K K V+P Sbjct: 133 AKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNP 166 >gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens] Length = 602 Score = 56.6 bits (135), Expect = 4e-08 Identities = 26/87 (29%), Positives = 51/87 (58%) Query: 38 DKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDE 97 ++ + I++P+NAFM++ K+ R ++ + +A ++++LG+ W AL+ ++ Y + Sbjct: 343 EEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYEL 402 Query: 98 AERLRLQHMQDYPNYKYRPRRKKQAKR 124 A + R HMQ YP + R K+ KR Sbjct: 403 ARKERQLHMQLYPGWSARDNYGKKKKR 429 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.133 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,789,228 Number of Sequences: 37866 Number of extensions: 1339169 Number of successful extensions: 6361 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 156 Number of HSP's successfully gapped in prelim test: 400 Number of HSP's that attempted gapping in prelim test: 5593 Number of HSP's gapped (non-prelim): 1232 length of query: 388 length of database: 18,247,518 effective HSP length: 104 effective length of query: 284 effective length of database: 14,309,454 effective search space: 4063884936 effective search space used: 4063884936 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.