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Search of human proteins with 13654237
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13654237 protein kinase, DNA-activated, catalytic
polypeptide isoform 1 [Homo sapiens]
(4128 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13654237 protein kinase, DNA-activated, catalytic polypeptide... 8221 0.0
gi|126032350 protein kinase, DNA-activated, catalytic polypeptid... 8145 0.0
gi|113430845 PREDICTED: similar to protein kinase, DNA-activated... 8131 0.0
gi|157266317 ataxia telangiectasia and Rad3 related protein [Hom... 159 7e-38
gi|169165926 PREDICTED: similar to ataxia telangiectasia and Rad... 159 7e-38
gi|4826730 FK506 binding protein 12-rapamycin associated protein... 149 4e-35
gi|20336199 ataxia telangiectasia mutated isoform 2 [Homo sapiens] 133 3e-30
gi|71902540 ataxia telangiectasia mutated isoform 1 [Homo sapiens] 133 3e-30
gi|169218268 PREDICTED: similar to Serine-protein kinase ATM, pa... 133 3e-30
gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens] 122 1e-26
gi|4507691 transformation/transcription domain-associated protei... 74 4e-12
gi|156564405 catalytic phosphatidylinositol 3-kinase delta [Homo... 73 7e-12
gi|21237725 phosphoinositide-3-kinase, catalytic, gamma polypept... 72 1e-11
gi|5453894 catalytic phosphatidylinositol 3-kinase beta [Homo sa... 65 2e-09
gi|169218238 PREDICTED: similar to ataxia telangiectasia and Rad... 52 2e-05
gi|34761064 catalytic phosphatidylinositol 3-kinase 3 [Homo sapi... 50 5e-05
gi|4505809 catalytic phosphatidylinositol 4-kinase beta [Homo sa... 48 2e-04
gi|54792082 phosphoinositide-3-kinase, catalytic, alpha polypept... 45 0.001
gi|194353959 phosphoinositide-3-kinase, class 2 gamma polypeptid... 45 0.001
gi|194097347 phosphoinositide-3-kinase, class 2 beta polypeptide... 42 0.010
gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptid... 42 0.016
gi|148886661 exportin 4 [Homo sapiens] 36 0.69
gi|223941912 coiled-coil domain containing 135 [Homo sapiens] 36 0.90
gi|188497683 FAST kinase domains 1 [Homo sapiens] 35 1.2
gi|41352697 centromere protein I [Homo sapiens] 34 2.6
gi|122937502 transmembrane channel-like 3 [Homo sapiens] 34 3.4
gi|27734911 DAZ interacting protein 1-like [Homo sapiens] 33 5.9
gi|4505807 phosphatidylinositol 4-kinase type 3 alpha isoform 1 ... 33 7.7
gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform ... 33 7.7
gi|12083581 phosphoinositide-specific phospholipase C beta 1 iso... 33 7.7
>gi|13654237 protein kinase, DNA-activated, catalytic polypeptide
isoform 1 [Homo sapiens]
Length = 4128
Score = 8221 bits (21331), Expect = 0.0
Identities = 4128/4128 (100%), Positives = 4128/4128 (100%)
Query: 1 MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS 60
MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS
Sbjct: 1 MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS 60
Query: 61 RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA 120
RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA
Sbjct: 61 RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA 120
Query: 121 AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL 180
AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL
Sbjct: 121 AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL 180
Query: 181 LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE 240
LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE
Sbjct: 181 LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE 240
Query: 241 DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW 300
DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW
Sbjct: 241 DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW 300
Query: 301 CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS 360
CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS
Sbjct: 301 CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS 360
Query: 361 IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDDRVYQMPSFLQSVASV 420
IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDDRVYQMPSFLQSVASV
Sbjct: 361 IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDDRVYQMPSFLQSVASV 420
Query: 421 LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS 480
LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS
Sbjct: 421 LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS 480
Query: 481 TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM 540
TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM
Sbjct: 481 TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM 540
Query: 541 MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV 600
MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV
Sbjct: 541 MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV 600
Query: 601 WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL 660
WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL
Sbjct: 601 WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL 660
Query: 661 PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ 720
PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ
Sbjct: 661 PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ 720
Query: 721 YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI 780
YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI
Sbjct: 721 YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI 780
Query: 781 DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL 840
DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL
Sbjct: 781 DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL 840
Query: 841 SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE 900
SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE
Sbjct: 841 SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE 900
Query: 901 MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ 960
MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ
Sbjct: 901 MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ 960
Query: 961 LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLEAILDGIVDP 1020
LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLEAILDGIVDP
Sbjct: 961 LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLEAILDGIVDP 1020
Query: 1021 VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL 1080
VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL
Sbjct: 1021 VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL 1080
Query: 1081 AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK 1140
AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK
Sbjct: 1081 AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK 1140
Query: 1141 KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG 1200
KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG
Sbjct: 1141 KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG 1200
Query: 1201 NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL 1260
NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL
Sbjct: 1201 NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL 1260
Query: 1261 LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN 1320
LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN
Sbjct: 1261 LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN 1320
Query: 1321 RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA 1380
RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA
Sbjct: 1321 RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA 1380
Query: 1381 SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD 1440
SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD
Sbjct: 1381 SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD 1440
Query: 1441 AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL 1500
AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL
Sbjct: 1441 AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL 1500
Query: 1501 PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY 1560
PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY
Sbjct: 1501 PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY 1560
Query: 1561 SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT 1620
SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT
Sbjct: 1561 SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT 1620
Query: 1621 TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA 1680
TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA
Sbjct: 1621 TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA 1680
Query: 1681 DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV 1740
DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV
Sbjct: 1681 DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV 1740
Query: 1741 DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES 1800
DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES
Sbjct: 1741 DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES 1800
Query: 1801 VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE 1860
VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE
Sbjct: 1801 VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE 1860
Query: 1861 STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY 1920
STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY
Sbjct: 1861 STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY 1920
Query: 1921 DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN 1980
DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN
Sbjct: 1921 DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN 1980
Query: 1981 LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM 2040
LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM
Sbjct: 1981 LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM 2040
Query: 2041 SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL 2100
SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL
Sbjct: 2041 SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL 2100
Query: 2101 VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY 2160
VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY
Sbjct: 2101 VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY 2160
Query: 2161 AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM 2220
AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM
Sbjct: 2161 AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM 2220
Query: 2221 KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV 2280
KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV
Sbjct: 2221 KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV 2280
Query: 2281 MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES 2340
MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES
Sbjct: 2281 MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES 2340
Query: 2341 LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV 2400
LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV
Sbjct: 2341 LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV 2400
Query: 2401 VLCRVEGMTELYFQLKSKDFVQVMRHRDDERQKVCLDIIYKMMPKLKPVELRELLNPVVE 2460
VLCRVEGMTELYFQLKSKDFVQVMRHRDDERQKVCLDIIYKMMPKLKPVELRELLNPVVE
Sbjct: 2401 VLCRVEGMTELYFQLKSKDFVQVMRHRDDERQKVCLDIIYKMMPKLKPVELRELLNPVVE 2460
Query: 2461 FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI 2520
FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI
Sbjct: 2461 FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI 2520
Query: 2521 IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP 2580
IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP
Sbjct: 2521 IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP 2580
Query: 2581 LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ 2640
LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ
Sbjct: 2581 LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ 2640
Query: 2641 QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF 2700
QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF
Sbjct: 2641 QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF 2700
Query: 2701 GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE 2760
GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE
Sbjct: 2701 GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE 2760
Query: 2761 LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM 2820
LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM
Sbjct: 2761 LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM 2820
Query: 2821 DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC 2880
DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC
Sbjct: 2821 DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC 2880
Query: 2881 LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR 2940
LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR
Sbjct: 2881 LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR 2940
Query: 2941 GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD 3000
GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD
Sbjct: 2941 GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD 3000
Query: 3001 CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS 3060
CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS
Sbjct: 3001 CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS 3060
Query: 3061 LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL 3120
LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL
Sbjct: 3061 LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL 3120
Query: 3121 LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD 3180
LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD
Sbjct: 3121 LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD 3180
Query: 3181 DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM 3240
DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM
Sbjct: 3181 DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM 3240
Query: 3241 KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV 3300
KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV
Sbjct: 3241 KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV 3300
Query: 3301 LKTVSLLDENNVSSYLSKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL 3360
LKTVSLLDENNVSSYLSKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL
Sbjct: 3301 LKTVSLLDENNVSSYLSKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL 3360
Query: 3361 ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC 3420
ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC
Sbjct: 3361 ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC 3420
Query: 3421 DQQLRKEEENASVIDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL 3480
DQQLRKEEENASVIDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL
Sbjct: 3421 DQQLRKEEENASVIDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL 3480
Query: 3481 SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY 3540
SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY
Sbjct: 3481 SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY 3540
Query: 3541 SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP 3600
SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP
Sbjct: 3541 SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP 3600
Query: 3601 VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN 3660
VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN
Sbjct: 3601 VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN 3660
Query: 3661 DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA 3720
DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA
Sbjct: 3661 DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA 3720
Query: 3721 GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA 3780
GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA
Sbjct: 3721 GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA 3780
Query: 3781 CSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPRAPPCEYK 3840
CSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPRAPPCEYK
Sbjct: 3781 CSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPRAPPCEYK 3840
Query: 3841 DWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLAL 3900
DWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLAL
Sbjct: 3841 DWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLAL 3900
Query: 3901 RSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMP 3960
RSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMP
Sbjct: 3901 RSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMP 3960
Query: 3961 FRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKM 4020
FRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKM
Sbjct: 3961 FRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKM 4020
Query: 4021 LKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAV 4080
LKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAV
Sbjct: 4021 LKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAV 4080
Query: 4081 ARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEPWM 4128
ARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEPWM
Sbjct: 4081 ARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEPWM 4128
>gi|126032350 protein kinase, DNA-activated, catalytic polypeptide
isoform 2 [Homo sapiens]
Length = 4097
Score = 8145 bits (21135), Expect = 0.0
Identities = 4097/4128 (99%), Positives = 4097/4128 (99%), Gaps = 31/4128 (0%)
Query: 1 MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS 60
MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS
Sbjct: 1 MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS 60
Query: 61 RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA 120
RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA
Sbjct: 61 RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA 120
Query: 121 AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL 180
AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL
Sbjct: 121 AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL 180
Query: 181 LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE 240
LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE
Sbjct: 181 LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE 240
Query: 241 DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW 300
DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW
Sbjct: 241 DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW 300
Query: 301 CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS 360
CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS
Sbjct: 301 CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS 360
Query: 361 IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDDRVYQMPSFLQSVASV 420
IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDDRVYQMPSFLQSVASV
Sbjct: 361 IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDDRVYQMPSFLQSVASV 420
Query: 421 LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS 480
LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS
Sbjct: 421 LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS 480
Query: 481 TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM 540
TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM
Sbjct: 481 TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM 540
Query: 541 MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV 600
MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV
Sbjct: 541 MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV 600
Query: 601 WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL 660
WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL
Sbjct: 601 WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL 660
Query: 661 PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ 720
PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ
Sbjct: 661 PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ 720
Query: 721 YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI 780
YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI
Sbjct: 721 YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI 780
Query: 781 DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL 840
DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL
Sbjct: 781 DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL 840
Query: 841 SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE 900
SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE
Sbjct: 841 SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE 900
Query: 901 MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ 960
MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ
Sbjct: 901 MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ 960
Query: 961 LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLEAILDGIVDP 1020
LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLEAILDGIVDP
Sbjct: 961 LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLEAILDGIVDP 1020
Query: 1021 VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL 1080
VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL
Sbjct: 1021 VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL 1080
Query: 1081 AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK 1140
AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK
Sbjct: 1081 AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK 1140
Query: 1141 KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG 1200
KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG
Sbjct: 1141 KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG 1200
Query: 1201 NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL 1260
NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL
Sbjct: 1201 NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL 1260
Query: 1261 LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN 1320
LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN
Sbjct: 1261 LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN 1320
Query: 1321 RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA 1380
RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA
Sbjct: 1321 RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA 1380
Query: 1381 SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD 1440
SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD
Sbjct: 1381 SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD 1440
Query: 1441 AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL 1500
AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL
Sbjct: 1441 AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL 1500
Query: 1501 PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY 1560
PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY
Sbjct: 1501 PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY 1560
Query: 1561 SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT 1620
SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT
Sbjct: 1561 SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT 1620
Query: 1621 TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA 1680
TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA
Sbjct: 1621 TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA 1680
Query: 1681 DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV 1740
DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV
Sbjct: 1681 DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV 1740
Query: 1741 DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES 1800
DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES
Sbjct: 1741 DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES 1800
Query: 1801 VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE 1860
VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE
Sbjct: 1801 VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE 1860
Query: 1861 STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY 1920
STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY
Sbjct: 1861 STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY 1920
Query: 1921 DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN 1980
DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN
Sbjct: 1921 DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN 1980
Query: 1981 LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM 2040
LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM
Sbjct: 1981 LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM 2040
Query: 2041 SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL 2100
SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL
Sbjct: 2041 SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL 2100
Query: 2101 VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY 2160
VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY
Sbjct: 2101 VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY 2160
Query: 2161 AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM 2220
AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM
Sbjct: 2161 AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM 2220
Query: 2221 KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV 2280
KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV
Sbjct: 2221 KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV 2280
Query: 2281 MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES 2340
MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES
Sbjct: 2281 MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES 2340
Query: 2341 LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV 2400
LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV
Sbjct: 2341 LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV 2400
Query: 2401 VLCRVEGMTELYFQLKSKDFVQVMRHRDDERQKVCLDIIYKMMPKLKPVELRELLNPVVE 2460
VLCRVEGMTELYFQLKSKDFVQVMRHRDDERQKVCLDIIYKMMPKLKPVELRELLNPVVE
Sbjct: 2401 VLCRVEGMTELYFQLKSKDFVQVMRHRDDERQKVCLDIIYKMMPKLKPVELRELLNPVVE 2460
Query: 2461 FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI 2520
FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI
Sbjct: 2461 FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI 2520
Query: 2521 IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP 2580
IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP
Sbjct: 2521 IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP 2580
Query: 2581 LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ 2640
LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ
Sbjct: 2581 LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ 2640
Query: 2641 QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF 2700
QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF
Sbjct: 2641 QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF 2700
Query: 2701 GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE 2760
GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE
Sbjct: 2701 GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE 2760
Query: 2761 LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM 2820
LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM
Sbjct: 2761 LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM 2820
Query: 2821 DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC 2880
DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC
Sbjct: 2821 DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC 2880
Query: 2881 LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR 2940
LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR
Sbjct: 2881 LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR 2940
Query: 2941 GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD 3000
GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD
Sbjct: 2941 GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD 3000
Query: 3001 CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS 3060
CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS
Sbjct: 3001 CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS 3060
Query: 3061 LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL 3120
LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL
Sbjct: 3061 LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL 3120
Query: 3121 LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD 3180
LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD
Sbjct: 3121 LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD 3180
Query: 3181 DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM 3240
DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM
Sbjct: 3181 DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM 3240
Query: 3241 KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV 3300
KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV
Sbjct: 3241 KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV 3300
Query: 3301 LKTVSLLDENNVSSYLSKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL 3360
LKTVSLLDENNVSSYLSKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL
Sbjct: 3301 LKTVSLLDENNVSSYLSKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL 3360
Query: 3361 ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC 3420
ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC
Sbjct: 3361 ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC 3420
Query: 3421 DQQLRKEEENASVIDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL 3480
DQQLRKEEENASVIDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL
Sbjct: 3421 DQQLRKEEENASVIDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL 3480
Query: 3481 SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY 3540
SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY
Sbjct: 3481 SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY 3540
Query: 3541 SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP 3600
SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP
Sbjct: 3541 SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP 3600
Query: 3601 VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN 3660
VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN
Sbjct: 3601 VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN 3660
Query: 3661 DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA 3720
DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA
Sbjct: 3661 DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA 3720
Query: 3721 GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA 3780
GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA
Sbjct: 3721 GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA 3780
Query: 3781 CSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPRAPPCEYK 3840
CSQRALQLRTYSVVPMTS SDPRAPPCEYK
Sbjct: 3781 CSQRALQLRTYSVVPMTS-------------------------------SDPRAPPCEYK 3809
Query: 3841 DWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLAL 3900
DWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLAL
Sbjct: 3810 DWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLAL 3869
Query: 3901 RSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMP 3960
RSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMP
Sbjct: 3870 RSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMP 3929
Query: 3961 FRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKM 4020
FRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKM
Sbjct: 3930 FRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKM 3989
Query: 4021 LKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAV 4080
LKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAV
Sbjct: 3990 LKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAV 4049
Query: 4081 ARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEPWM 4128
ARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEPWM
Sbjct: 4050 ARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEPWM 4097
>gi|113430845 PREDICTED: similar to protein kinase, DNA-activated,
catalytic polypeptide [Homo sapiens]
Length = 4096
Score = 8131 bits (21097), Expect = 0.0
Identities = 4092/4128 (99%), Positives = 4094/4128 (99%), Gaps = 32/4128 (0%)
Query: 1 MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS 60
MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS
Sbjct: 1 MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS 60
Query: 61 RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA 120
RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA
Sbjct: 61 RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA 120
Query: 121 AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL 180
AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL
Sbjct: 121 AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL 180
Query: 181 LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE 240
LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE
Sbjct: 181 LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE 240
Query: 241 DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW 300
DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW
Sbjct: 241 DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW 300
Query: 301 CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS 360
CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS
Sbjct: 301 CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS 360
Query: 361 IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDDRVYQMPSFLQSVASV 420
IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGD RVYQMPSFLQSVASV
Sbjct: 361 IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDYRVYQMPSFLQSVASV 420
Query: 421 LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS 480
LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS
Sbjct: 421 LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS 480
Query: 481 TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM 540
TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM
Sbjct: 481 TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM 540
Query: 541 MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV 600
MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV
Sbjct: 541 MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV 600
Query: 601 WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL 660
WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL
Sbjct: 601 WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL 660
Query: 661 PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ 720
PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ
Sbjct: 661 PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ 720
Query: 721 YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI 780
YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI
Sbjct: 721 YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI 780
Query: 781 DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL 840
DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL
Sbjct: 781 DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL 840
Query: 841 SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE 900
SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE
Sbjct: 841 SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE 900
Query: 901 MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ 960
MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ
Sbjct: 901 MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ 960
Query: 961 LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLEAILDGIVDP 1020
LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTV+LLEAILDGIVDP
Sbjct: 961 LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVSLLEAILDGIVDP 1020
Query: 1021 VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL 1080
VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL
Sbjct: 1021 VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL 1080
Query: 1081 AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK 1140
AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK
Sbjct: 1081 AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK 1140
Query: 1141 KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG 1200
KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG
Sbjct: 1141 KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG 1200
Query: 1201 NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL 1260
NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL
Sbjct: 1201 NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL 1260
Query: 1261 LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN 1320
LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN
Sbjct: 1261 LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN 1320
Query: 1321 RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA 1380
RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA
Sbjct: 1321 RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA 1380
Query: 1381 SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD 1440
SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD
Sbjct: 1381 SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD 1440
Query: 1441 AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL 1500
AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL
Sbjct: 1441 AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL 1500
Query: 1501 PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY 1560
PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY
Sbjct: 1501 PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY 1560
Query: 1561 SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT 1620
SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT
Sbjct: 1561 SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT 1620
Query: 1621 TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA 1680
TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA
Sbjct: 1621 TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA 1680
Query: 1681 DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV 1740
DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV
Sbjct: 1681 DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV 1740
Query: 1741 DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES 1800
DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES
Sbjct: 1741 DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES 1800
Query: 1801 VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE 1860
VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE
Sbjct: 1801 VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE 1860
Query: 1861 STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY 1920
STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY
Sbjct: 1861 STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY 1920
Query: 1921 DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN 1980
DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN
Sbjct: 1921 DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN 1980
Query: 1981 LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM 2040
LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM
Sbjct: 1981 LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM 2040
Query: 2041 SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL 2100
SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL
Sbjct: 2041 SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL 2100
Query: 2101 VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY 2160
VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY
Sbjct: 2101 VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY 2160
Query: 2161 AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM 2220
AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM
Sbjct: 2161 AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM 2220
Query: 2221 KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV 2280
KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV
Sbjct: 2221 KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV 2280
Query: 2281 MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES 2340
MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES
Sbjct: 2281 MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES 2340
Query: 2341 LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV 2400
LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV
Sbjct: 2341 LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV 2400
Query: 2401 VLCRVEGMTELYFQLKSKDFVQVMRHRDDERQKVCLDIIYKMMPKLKPVELRELLNPVVE 2460
VLCRVEGMTELYFQLKSKDFVQVMRHRD ERQKVCLDIIYKMMPKLKPVELRELLNPVVE
Sbjct: 2401 VLCRVEGMTELYFQLKSKDFVQVMRHRD-ERQKVCLDIIYKMMPKLKPVELRELLNPVVE 2459
Query: 2461 FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI 2520
FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI
Sbjct: 2460 FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI 2519
Query: 2521 IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP 2580
IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP
Sbjct: 2520 IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP 2579
Query: 2581 LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ 2640
LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ
Sbjct: 2580 LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ 2639
Query: 2641 QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF 2700
QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF
Sbjct: 2640 QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF 2699
Query: 2701 GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE 2760
GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE
Sbjct: 2700 GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE 2759
Query: 2761 LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM 2820
LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM
Sbjct: 2760 LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM 2819
Query: 2821 DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC 2880
DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC
Sbjct: 2820 DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC 2879
Query: 2881 LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR 2940
LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR
Sbjct: 2880 LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR 2939
Query: 2941 GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD 3000
GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD
Sbjct: 2940 GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD 2999
Query: 3001 CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS 3060
CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS
Sbjct: 3000 CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS 3059
Query: 3061 LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL 3120
LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL
Sbjct: 3060 LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL 3119
Query: 3121 LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD 3180
LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD
Sbjct: 3120 LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD 3179
Query: 3181 DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM 3240
DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM
Sbjct: 3180 DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM 3239
Query: 3241 KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV 3300
KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV
Sbjct: 3240 KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV 3299
Query: 3301 LKTVSLLDENNVSSYLSKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL 3360
LKTVSLLDENNVSSYL+KNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL
Sbjct: 3300 LKTVSLLDENNVSSYLNKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL 3359
Query: 3361 ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC 3420
ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC
Sbjct: 3360 ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC 3419
Query: 3421 DQQLRKEEENASVIDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL 3480
DQQLRKEEENASV DSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL
Sbjct: 3420 DQQLRKEEENASVTDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL 3479
Query: 3481 SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY 3540
SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY
Sbjct: 3480 SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY 3539
Query: 3541 SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP 3600
SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP
Sbjct: 3540 SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP 3599
Query: 3601 VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN 3660
VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN
Sbjct: 3600 VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN 3659
Query: 3661 DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA 3720
DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA
Sbjct: 3660 DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA 3719
Query: 3721 GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA 3780
GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA
Sbjct: 3720 GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA 3779
Query: 3781 CSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPRAPPCEYK 3840
CSQRALQLRTYSVVPMTS SDPRAPPCEYK
Sbjct: 3780 CSQRALQLRTYSVVPMTS-------------------------------SDPRAPPCEYK 3808
Query: 3841 DWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLAL 3900
DWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLAL
Sbjct: 3809 DWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLAL 3868
Query: 3901 RSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMP 3960
RSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMP
Sbjct: 3869 RSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMP 3928
Query: 3961 FRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKM 4020
FRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKM
Sbjct: 3929 FRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKM 3988
Query: 4021 LKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAV 4080
LKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAV
Sbjct: 3989 LKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAV 4048
Query: 4081 ARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEPWM 4128
ARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEPWM
Sbjct: 4049 ARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEPWM 4096
>gi|157266317 ataxia telangiectasia and Rad3 related protein [Homo
sapiens]
Length = 2644
Score = 159 bits (401), Expect = 7e-38
Identities = 116/431 (26%), Positives = 188/431 (43%), Gaps = 82/431 (19%)
Query: 3710 KPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQ 3769
+P P + IAGFD+ V ++ASL++PK+I ++G D + + + K +DLR+D R+ +
Sbjct: 2284 EPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNS 2343
Query: 3770 VMNGILAQDSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYL 3829
++N L +D+ +R L +RTY+V+P+ G+IEW+ NT L+ +L T +EK Y+
Sbjct: 2344 LINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPIL--TKLYKEKGVYM 2401
Query: 3830 SDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVR 3889
+ C ++ K A +E + FR+ + F+R
Sbjct: 2402 TGKELRQC-------------------MLPKSAALSEKLKVFREFLLPRHPPIFHEWFLR 2442
Query: 3890 MSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSA 3949
P ++ + RS + S A++ + +ILG+GDRH N + TG + +DF F
Sbjct: 2443 TFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKG 2502
Query: 3950 TQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEP 4009
F VPE++PFRLT +N M PM GL +R R L + + F+ +P
Sbjct: 2503 ETF-EVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDP 2561
Query: 4010 SFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHE 4069
+W K +K GH
Sbjct: 2562 LVEW----SKPVK--------------------------------------------GHS 2573
Query: 4070 KAPAFRDYVAVARGSKDHNIRAQEPESG------------LSEETQVKCLMDQATDPNIL 4117
KAP V +K H + ++ G LS E V L+ +ATD N+L
Sbjct: 2574 KAPLNETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLL 2633
Query: 4118 GRTWEGWEPWM 4128
+ + GW P+M
Sbjct: 2634 CQMYLGWTPYM 2644
>gi|169165926 PREDICTED: similar to ataxia telangiectasia and Rad3
related protein, partial [Homo sapiens]
Length = 386
Score = 159 bits (401), Expect = 7e-38
Identities = 116/431 (26%), Positives = 188/431 (43%), Gaps = 82/431 (19%)
Query: 3710 KPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQ 3769
+P P + IAGFD+ V ++ASL++PK+I ++G D + + + K +DLR+D R+ +
Sbjct: 26 EPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNS 85
Query: 3770 VMNGILAQDSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYL 3829
++N L +D+ +R L +RTY+V+P+ G+IEW+ NT L+ +L T +EK Y+
Sbjct: 86 LINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPIL--TKLYKEKGVYM 143
Query: 3830 SDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVR 3889
+ C ++ K A +E + FR+ + F+R
Sbjct: 144 TGKELRQC-------------------MLPKSAALSEKLKVFREFLLPRHPPIFHEWFLR 184
Query: 3890 MSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSA 3949
P ++ + RS + S A++ + +ILG+GDRH N + TG + +DF F
Sbjct: 185 TFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKG 244
Query: 3950 TQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEP 4009
F VPE++PFRLT +N M PM GL +R R L + + F+ +P
Sbjct: 245 ETF-EVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDP 303
Query: 4010 SFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHE 4069
+W K +K GH
Sbjct: 304 LVEW----SKPVK--------------------------------------------GHS 315
Query: 4070 KAPAFRDYVAVARGSKDHNIRAQEPESG------------LSEETQVKCLMDQATDPNIL 4117
KAP V +K H + ++ G LS E V L+ +ATD N+L
Sbjct: 316 KAPLNETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLL 375
Query: 4118 GRTWEGWEPWM 4128
+ + GW P+M
Sbjct: 376 CQMYLGWTPYM 386
>gi|4826730 FK506 binding protein 12-rapamycin associated protein 1
[Homo sapiens]
Length = 2549
Score = 149 bits (377), Expect = 4e-35
Identities = 135/544 (24%), Positives = 251/544 (46%), Gaps = 53/544 (9%)
Query: 3487 ISSVPCWQFISW---ISHMVALLDKDQAVA---VQHSVEEITDNYPQAIVYPFIISSESY 3540
+ V Q +W I ++A +D + + + + +I +PQA++YP ++S+S
Sbjct: 1924 VEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKST 1983
Query: 3541 SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP 3600
+ + +K + + + L +Q + ++L +L+ + ++ E ++
Sbjct: 1984 TTARHNAANKILKNMCEHSNTL-----VQQAMMVSEELIRVAILWHEMWHEGLEEASRLY 2038
Query: 3601 VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGK------EFDKHFGKGGSKLLRM 3654
++N++ M+E + + F Q +G+ E+ + + K G+
Sbjct: 2039 FGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGN----- 2093
Query: 3655 KLSDFNDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRN-ELEIPGQYDGRGKPLP 3713
+ D ++ + SK L K+ R+ EL +PG YD +P+
Sbjct: 2094 -VKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPN-QPI- 2150
Query: 3714 EYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNG 3773
+RI + V+ S +RP+++ + G + E FL+KG EDLRQD+RV QLF ++N
Sbjct: 2151 ---IRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNT 2207
Query: 3774 ILAQDSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPR 3833
+LA D ++ L ++ Y+V+P+++ GLI W+ + TL L+ + +E+K L+
Sbjct: 2208 LLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRD--YREKKKILLN--- 2262
Query: 3834 APPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTS 3893
E++ L +M+ +D M + V F + D L + S S
Sbjct: 2263 ---IEHRIML-RMAPDYDHLTLM---------QKVEVFEHAVNNTAGDDLAKLLWLKSPS 2309
Query: 3894 PEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFL 3953
E + R+++ S A++ + +ILG+GDRH +N M+ +G ++ IDFG F A
Sbjct: 2310 SEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTRE 2369
Query: 3954 PVPELMPFRLTRQFINLMLPMKETGL--MYSIMVH-ALRAFRSDPGLLTNTMDVFVKEPS 4010
PE +PFRLTR N M+ TGL Y I H + R + ++ FV +P
Sbjct: 2370 KFPEKIPFRLTRMLTN---AMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPL 2426
Query: 4011 FDWK 4014
+W+
Sbjct: 2427 LNWR 2430
>gi|20336199 ataxia telangiectasia mutated isoform 2 [Homo sapiens]
Length = 1708
Score = 133 bits (335), Expect = 3e-30
Identities = 112/420 (26%), Positives = 178/420 (42%), Gaps = 52/420 (12%)
Query: 3717 VRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILA 3776
V I F + + PK I G D +E LVKG +DLRQD ++Q+FQ+ N +L
Sbjct: 1333 VTIQSFKAEFRLAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQ 1392
Query: 3777 QDSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPRAPP 3836
+++ +R L + TY VVP++ R G++EW TV + + L+N K +D A
Sbjct: 1393 RNTETRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFLVNNEDGAHKRYRPNDFSAFQ 1452
Query: 3837 CEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEA 3896
C+ K + ++ K Y + + V + E + P
Sbjct: 1453 CQKK--MMEVQKKSFEEKYEVFMDVCQNFQPVFRYFCMEKFL--------------DPAI 1496
Query: 3897 FLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVP 3956
+ R + S A I +ILG+GDRH+ N ++ ++ ++ ID G AF + LP P
Sbjct: 1497 WFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQG-KILPTP 1555
Query: 3957 ELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNF 4016
E +PFRLTR ++ M G+ + R+ L ++V + +P FDW
Sbjct: 1556 ETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMN 1615
Query: 4017 EQKMLKKGGSWIQEINVAEKNWYPRQKI--CYAKRKLAGANPAVITCDELLLGHEKAPAF 4074
K L ++Q+ E +P KR L+ + + E +L
Sbjct: 1616 PLKAL-----YLQQRPEDETELHPTLNADDQECKRNLSDIDQSFNKVAERVL-------- 1662
Query: 4075 RDYVAVARGSKDHNIRAQEPESGLSEET------QVKCLMDQATDPNILGRTWEGWEPWM 4128
+R QE G+ E T QV L+ QA DP L R + GW+ W+
Sbjct: 1663 --------------MRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV 1708
>gi|71902540 ataxia telangiectasia mutated isoform 1 [Homo sapiens]
Length = 3056
Score = 133 bits (335), Expect = 3e-30
Identities = 112/420 (26%), Positives = 178/420 (42%), Gaps = 52/420 (12%)
Query: 3717 VRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILA 3776
V I F + + PK I G D +E LVKG +DLRQD ++Q+FQ+ N +L
Sbjct: 2681 VTIQSFKAEFRLAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQ 2740
Query: 3777 QDSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPRAPP 3836
+++ +R L + TY VVP++ R G++EW TV + + L+N K +D A
Sbjct: 2741 RNTETRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFLVNNEDGAHKRYRPNDFSAFQ 2800
Query: 3837 CEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEA 3896
C+ K + ++ K Y + + V + E + P
Sbjct: 2801 CQKK--MMEVQKKSFEEKYEVFMDVCQNFQPVFRYFCMEKFL--------------DPAI 2844
Query: 3897 FLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVP 3956
+ R + S A I +ILG+GDRH+ N ++ ++ ++ ID G AF + LP P
Sbjct: 2845 WFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQG-KILPTP 2903
Query: 3957 ELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNF 4016
E +PFRLTR ++ M G+ + R+ L ++V + +P FDW
Sbjct: 2904 ETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMN 2963
Query: 4017 EQKMLKKGGSWIQEINVAEKNWYPRQKI--CYAKRKLAGANPAVITCDELLLGHEKAPAF 4074
K L ++Q+ E +P KR L+ + + E +L
Sbjct: 2964 PLKAL-----YLQQRPEDETELHPTLNADDQECKRNLSDIDQSFNKVAERVL-------- 3010
Query: 4075 RDYVAVARGSKDHNIRAQEPESGLSEET------QVKCLMDQATDPNILGRTWEGWEPWM 4128
+R QE G+ E T QV L+ QA DP L R + GW+ W+
Sbjct: 3011 --------------MRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV 3056
>gi|169218268 PREDICTED: similar to Serine-protein kinase ATM, partial
[Homo sapiens]
Length = 2934
Score = 133 bits (335), Expect = 3e-30
Identities = 112/420 (26%), Positives = 178/420 (42%), Gaps = 52/420 (12%)
Query: 3717 VRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILA 3776
V I F + + PK I G D +E LVKG +DLRQD ++Q+FQ+ N +L
Sbjct: 2559 VTIQSFKAEFRLAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQ 2618
Query: 3777 QDSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPRAPP 3836
+++ +R L + TY VVP++ R G++EW TV + + L+N K +D A
Sbjct: 2619 RNTETRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFLVNNEDGAHKRYRPNDFSAFQ 2678
Query: 3837 CEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEA 3896
C+ K + ++ K Y + + V + E + P
Sbjct: 2679 CQKK--MMEVQKKSFEEKYEVFMDVCQNFQPVFRYFCMEKFL--------------DPAI 2722
Query: 3897 FLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVP 3956
+ R + S A I +ILG+GDRH+ N ++ ++ ++ ID G AF + LP P
Sbjct: 2723 WFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQG-KILPTP 2781
Query: 3957 ELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNF 4016
E +PFRLTR ++ M G+ + R+ L ++V + +P FDW
Sbjct: 2782 ETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMN 2841
Query: 4017 EQKMLKKGGSWIQEINVAEKNWYPRQKI--CYAKRKLAGANPAVITCDELLLGHEKAPAF 4074
K L ++Q+ E +P KR L+ + + E +L
Sbjct: 2842 PLKAL-----YLQQRPEDETELHPTLNADDQECKRNLSDIDQSFDKVAERVL-------- 2888
Query: 4075 RDYVAVARGSKDHNIRAQEPESGLSEET------QVKCLMDQATDPNILGRTWEGWEPWM 4128
+R QE G+ E T QV L+ QA DP L R + GW+ W+
Sbjct: 2889 --------------MRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV 2934
>gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]
Length = 3661
Score = 122 bits (305), Expect = 1e-26
Identities = 89/366 (24%), Positives = 162/366 (44%), Gaps = 22/366 (6%)
Query: 3659 FNDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVR 3718
F +I L + K + L+E SPW++ E+ +PG+ R V
Sbjct: 2071 FKEIMLSLQQRAQKRASYILRLEEISPWLA----AMTNTEIALPGEVSARDT------VT 2120
Query: 3719 IAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQD 3778
I +T++ + +PK+++ G D + +P+L KG EDL D+R+ Q ++N + A
Sbjct: 2121 IHSVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATI 2180
Query: 3779 SACSQRALQLRTYSVVPMTSRLGLIEWLENTVTL---------KDLLLNTMSQEEKAAYL 3829
+ R YSV P+ +R GLI+W++ L ++ L ++
Sbjct: 2181 NRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQAQKAQDSYQTP 2240
Query: 3830 SDPRAPPCEYKDWLTKMS-GKHDVGAYMLMYKGANRTETVTS-FRKRESKVPADLLKRAF 3887
+P P + + +K+ VG + + + + + + P +LL +
Sbjct: 2241 QNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELMEATPPNLLAKEL 2300
Query: 3888 VRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFG 3947
T+P+ + + +A S A++ + +I+G+GDRHL+N ++ M TG V+ ID+ F
Sbjct: 2301 WSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFE 2360
Query: 3948 SATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVK 4007
+ L VPE +PFR+T+ + G+ L R L ++ FV
Sbjct: 2361 KG-KSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVY 2419
Query: 4008 EPSFDW 4013
+P DW
Sbjct: 2420 DPLVDW 2425
>gi|4507691 transformation/transcription domain-associated protein
[Homo sapiens]
Length = 3830
Score = 73.6 bits (179), Expect = 4e-12
Identities = 115/596 (19%), Positives = 229/596 (38%), Gaps = 100/596 (16%)
Query: 3490 VPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPF--------IISSESYS 3541
VP Q+++WI ++ L + + + + ++ YPQA+ +P I E Y
Sbjct: 3197 VPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPIRTLYLTLKIEQRERYK 3256
Query: 3542 ------------FKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWS 3589
++ + H +E + S L+ G++ + ++W
Sbjct: 3257 SDPGPIRATAPMWRCSRIMHMQRELHPTLLSSLE--GIVDQMV----------WFRENWH 3304
Query: 3590 NDVRAELAKTPVNKKNIEKMYERMY---AALGDPK-APGLGAFRRKFIQTFGKEFDK--- 3642
+V +L ++ + K Y + A+ D K P F +K + TFG +
Sbjct: 3305 EEVLRQL------QQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSN 3358
Query: 3643 ---HFGKGGSKLLRMKLSDFNDITNMLLLK----MNKDSKPPGNLK------ECSPWMS- 3688
F S+ L + LK + D PG++K + W+
Sbjct: 3359 VSTMFSSAASESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKI 3418
Query: 3689 --------------DFKVEFLRN------ELEIPGQYDGRGKPLP-EYHVRIAGFDERVT 3727
+ K FL N E+EIPG++ P P Y+++IA F RV
Sbjct: 3419 LEAKTKQLPKFFLIEEKCRFLSNFSAQTAEVEIPGEFL---MPKPTHYYIKIARFMPRVE 3475
Query: 3728 VMASLRRP-KRIIIRGHDEREHPFLVKGGEDL---RQDQRVEQLFQVMNGILAQDSACSQ 3783
++ +R+ IRGH+ + +P+LV L R+++RV QL +++N L + ++
Sbjct: 3476 IVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTK 3535
Query: 3784 RALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPRAPPCEYKDWL 3843
R L VV ++ ++ L+E ++++L ++ +++ + P Y D L
Sbjct: 3536 RHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKG-----IEHDNPISRYYDRL 3590
Query: 3844 TKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSH 3903
+ + ++ ++ ++ + VP +LK + + + R
Sbjct: 3591 ATVQARGTQASHQVLRDILKEVQS--------NMVPRSMLKEWALHTFPNATDYWTFRKM 3642
Query: 3904 FASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRL 3963
F ALI + ++L + + +A +TG + F AT L +PFRL
Sbjct: 3643 FTIQLALIGFAEFVLHLNRLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDANRPVPFRL 3702
Query: 3964 TRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQK 4019
T + + +G + + M+ R F + + +++ W Q+
Sbjct: 3703 TPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKKTQE 3758
>gi|156564405 catalytic phosphatidylinositol 3-kinase delta [Homo
sapiens]
Length = 1044
Score = 72.8 bits (177), Expect = 7e-12
Identities = 68/252 (26%), Positives = 107/252 (42%), Gaps = 60/252 (23%)
Query: 3724 ERVTVMASLRRPKRIIIRGHDEREHP---FLVKGGEDLRQDQRVEQLFQVMNGILAQDSA 3780
E+ T M S +P I+ + + K G+DLRQD Q+ Q+M+ + Q+
Sbjct: 747 EQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGL 806
Query: 3781 CSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPRAPPCEYK 3840
L++ Y +P R GLIE + + T+ ++ LN + AA+ D
Sbjct: 807 ----DLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALL------ 856
Query: 3841 DWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLAL 3900
+WL +SK P + L RA
Sbjct: 857 NWL-------------------------------KSKNPGEALDRAI------------- 872
Query: 3901 RSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGS-ATQFLPVPELM 3959
F S A C++ ++LGIGDRH +N M+ E+G + IDFGH G+ T+F E +
Sbjct: 873 -EEFTLSCAGYCVATYVLGIGDRHSDNIMI-RESGQLFHIDFGHFLGNFKTKFGINRERV 930
Query: 3960 PFRLTRQFINLM 3971
PF LT F++++
Sbjct: 931 PFILTYDFVHVI 942
>gi|21237725 phosphoinositide-3-kinase, catalytic, gamma polypeptide
[Homo sapiens]
Length = 1102
Score = 71.6 bits (174), Expect = 1e-11
Identities = 65/254 (25%), Positives = 105/254 (41%), Gaps = 63/254 (24%)
Query: 3724 ERVTVMASLRRPKRIIIRGHD-----EREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQD 3778
E+ VMAS ++P + + D + K G+DLRQD + Q+ ++M I +
Sbjct: 799 EKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETE 858
Query: 3779 SACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPRAPPCE 3838
S L L Y + ++G+IE +++ T+ + +T+
Sbjct: 859 SL----DLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNT--------------- 899
Query: 3839 YKDWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFL 3898
GA + E + + K +S + E F
Sbjct: 900 ----------------------GAFKDEVLNHWLKEKSP---------------TEEKFQ 922
Query: 3899 ALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPV-PE 3957
A F S A C++ ++LGIGDRH +N M+ ETG + IDFGH G+ FL + E
Sbjct: 923 AAVERFVYSCAGYCVATFVLGIGDRHNDNIMIT-ETGNLFHIDFGHILGNYKSFLGINKE 981
Query: 3958 LMPFRLTRQFINLM 3971
+PF LT F+ +M
Sbjct: 982 RVPFVLTPDFLFVM 995
>gi|5453894 catalytic phosphatidylinositol 3-kinase beta [Homo
sapiens]
Length = 1070
Score = 64.7 bits (156), Expect = 2e-09
Identities = 61/222 (27%), Positives = 96/222 (43%), Gaps = 57/222 (25%)
Query: 3751 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSRLGLIEWLENTV 3810
+ K G+DLRQD Q+ ++M+ +L +++ R L Y + R GLIE + +
Sbjct: 803 IFKNGDDLRQDMLTLQMLRLMD-LLWKEAGLDLRMLP---YGCLATGDRSGLIEVVSTSE 858
Query: 3811 TLKDLLLNTMSQEEKAAYLSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTS 3870
T+ D+ LN+ + AA+ D +WL + + D
Sbjct: 859 TIADIQLNSSNVAAAAAFNKDALL------NWLKEYNSGDD------------------- 893
Query: 3871 FRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMV 3930
L RA F S A C++ ++LGIGDRH +N MV
Sbjct: 894 ------------LDRAI--------------EEFTLSCAGYCVASYVLGIGDRHSDNIMV 927
Query: 3931 AMETGGVIGIDFGHAFGS-ATQFLPVPELMPFRLTRQFINLM 3971
+TG + IDFGH G+ ++F E +PF LT FI+++
Sbjct: 928 -KKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVI 968
>gi|169218238 PREDICTED: similar to ataxia telangiectasia and Rad3
related protein, partial [Homo sapiens]
Length = 2105
Score = 51.6 bits (122), Expect = 2e-05
Identities = 23/63 (36%), Positives = 42/63 (66%)
Query: 3710 KPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQ 3769
+P P + IAGFD+ V ++ASL++PK+I ++G D + + + K +DLR+D R+ +
Sbjct: 2042 EPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNS 2101
Query: 3770 VMN 3772
++N
Sbjct: 2102 LIN 2104
>gi|34761064 catalytic phosphatidylinositol 3-kinase 3 [Homo sapiens]
Length = 887
Score = 50.1 bits (118), Expect = 5e-05
Identities = 40/166 (24%), Positives = 81/166 (48%), Gaps = 11/166 (6%)
Query: 3645 GKGGSKLLRMKLSDFNDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQ 3704
G +++R L+ + L+ M + GN K+ + +++ L + E
Sbjct: 531 GDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKK-----KNERLQALLGDNEKMNL 585
Query: 3705 YDGRGKPLP-EYHVRIAGF-DERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQ 3762
D PLP E V+I G E T+ S P ++ + D ++P + K G+DLRQDQ
Sbjct: 586 SDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQ 645
Query: 3763 RVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSRLGLIEWLEN 3808
+ Q+ +M+ +L +++ L+L Y V+ +++ G ++++++
Sbjct: 646 LILQIISLMDKLLRKENL----DLKLTPYKVLATSTKHGFMQFIQS 687
Score = 44.7 bits (104), Expect = 0.002
Identities = 22/53 (41%), Positives = 33/53 (62%), Gaps = 1/53 (1%)
Query: 3904 FASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVP 3956
+ S A C+ +ILG+GDRHL+N ++ +TG + IDFG+ G + LP P
Sbjct: 725 YVKSCAGYCVITYILGVGDRHLDNLLLT-KTGKLFHIDFGYILGRDPKPLPPP 776
>gi|4505809 catalytic phosphatidylinositol 4-kinase beta [Homo
sapiens]
Length = 828
Score = 47.8 bits (112), Expect = 2e-04
Identities = 29/81 (35%), Positives = 47/81 (58%), Gaps = 2/81 (2%)
Query: 3891 STSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSAT 3950
S + EAFL+ + +F S A C+ ++L + DRH N ++ E G +I IDFG S+
Sbjct: 652 SYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAE-GHIIHIDFGFILSSSP 710
Query: 3951 QFLPVPELMPFRLTRQFINLM 3971
+ L E F+LT +F+++M
Sbjct: 711 RNLGF-ETSAFKLTTEFVDVM 730
>gi|54792082 phosphoinositide-3-kinase, catalytic, alpha polypeptide
[Homo sapiens]
Length = 1068
Score = 45.1 bits (105), Expect = 0.001
Identities = 28/66 (42%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
Query: 3904 FASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFG-SATQFLPVPELMPFR 3962
F S A C++ +ILGIGDRH +N MV + G + IDFGH +F E +PF
Sbjct: 897 FTRSCAGYCVATFILGIGDRHNSNIMV-KDDGQLFHIDFGHFLDHKKKKFGYKRERVPFV 955
Query: 3963 LTRQFI 3968
LT+ F+
Sbjct: 956 LTQDFL 961
Score = 33.5 bits (75), Expect = 4.5
Identities = 24/98 (24%), Positives = 44/98 (44%), Gaps = 10/98 (10%)
Query: 3724 ERVTVMASLRRPKRIIIRGHDE------REHPFLVKGGEDLRQDQRVEQLFQVMNGILAQ 3777
E +M+S +RP + D + + + K G+DLRQD Q+ ++M I
Sbjct: 767 EECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQN 826
Query: 3778 DSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDL 3815
L++ Y + + +GLIE + N+ T+ +
Sbjct: 827 QGL----DLRMLPYGCLSIGDCVGLIEVVRNSHTIMQI 860
>gi|194353959 phosphoinositide-3-kinase, class 2 gamma polypeptide
[Homo sapiens]
Length = 1445
Score = 45.1 bits (105), Expect = 0.001
Identities = 52/202 (25%), Positives = 80/202 (39%), Gaps = 58/202 (28%)
Query: 3751 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSRLGLIEWLENTV 3810
+ K G+DLRQD V QL QVM+ I Q+ +Q+ Y + GL++ + + V
Sbjct: 919 IFKAGDDLRQDMLVLQLIQVMDNIWLQEGL----DMQMIIYRCLSTGKDQGLVQMVPDAV 974
Query: 3811 TLKDLLLNTMSQEEKAAYLSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTS 3870
TL + + SG G + T+
Sbjct: 975 TLAK----------------------------IHRHSG----------LIGPLKENTIKK 996
Query: 3871 FRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMV 3930
+ + + + AD K ALR+ F S A C+ +ILG+ DRH +N M+
Sbjct: 997 WFSQHNHLKADYEK--------------ALRNFFYSC-AGWCVVTFILGVCDRHNDNIML 1041
Query: 3931 AMETGGVIGIDFGHAFGSATQF 3952
++G + IDFG G A F
Sbjct: 1042 T-KSGHMFHIDFGKFLGHAQTF 1062
>gi|194097347 phosphoinositide-3-kinase, class 2 beta polypeptide
[Homo sapiens]
Length = 1634
Score = 42.4 bits (98), Expect = 0.010
Identities = 52/203 (25%), Positives = 80/203 (39%), Gaps = 60/203 (29%)
Query: 3751 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSR-LGLIEWLENT 3809
+ K G+DLRQD Q+ ++M+ I Q+ R + R +S T R G++E + N
Sbjct: 1081 IFKCGDDLRQDMLTLQMIRIMSKIWVQEGL-DMRMVIFRCFS----TGRGRGMVEMIPNA 1135
Query: 3810 VTLKDLLLNTMSQEEKAAYLSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVT 3869
TL+ + + ++ P A DWL K H+ G
Sbjct: 1136 ETLRKI---QVEHGVTGSFKDRPLA------DWLQK----HNPGE--------------- 1167
Query: 3870 SFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFM 3929
D ++A +F S A C++ ++LGI DRH +N M
Sbjct: 1168 -----------DEYEKAV--------------ENFIYSCAGCCVATYVLGICDRHNDNIM 1202
Query: 3930 VAMETGGVIGIDFGHAFGSATQF 3952
+ TG + IDFG G A F
Sbjct: 1203 L-KTTGHMFHIDFGRFLGHAQMF 1224
>gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptide
[Homo sapiens]
Length = 1686
Score = 41.6 bits (96), Expect = 0.016
Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 6/123 (4%)
Query: 3889 RMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGS 3948
+ + S E + +F S A C++ ++LGI DRH +N M+ TG + IDFG G
Sbjct: 1217 KYNPSEEEYEKASENFIYSCAGCCVATYVLGICDRHNDNIML-RSTGHMFHIDFGKFLGH 1275
Query: 3949 ATQFLPVP-ELMPFRLTRQFINLMLPMKETGLMYSIMV----HALRAFRSDPGLLTNTMD 4003
A F + PF LT ++ ++ + + + V A R L N +
Sbjct: 1276 AQMFGSFKRDRAPFVLTSDMAYVINGGEKPTIRFQLFVDLCCQAYNLIRKQTNLFLNLLS 1335
Query: 4004 VFV 4006
+ +
Sbjct: 1336 LMI 1338
>gi|148886661 exportin 4 [Homo sapiens]
Length = 1151
Score = 36.2 bits (82), Expect = 0.69
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 25/179 (13%)
Query: 169 TVLEKVYELLGLLGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLS 228
T+ + Y+L+ + E+ P ++ E+LF++ + L+ MTS E V CL+ L+
Sbjct: 975 TLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSE----VCQLCLEALT 1030
Query: 229 SLLCNFTKSMEEDPQTSREIFNFVLKAIRPQIDLKRY------AVPSAGLRLFALHASQF 282
L K+ E D +F LK + + L+++ A A L LH +++
Sbjct: 1031 PLAEQCAKAQETDSPLFLATRHF-LKLVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEY 1089
Query: 283 S---TCLLDN------YVSLFEVLLKWCAHT-----NVELKKAALSALESFLKQVSNMV 327
S LL + Y L + K A + + + K A L +LE F+ V ++
Sbjct: 1090 SELVETLLSSQQDPVIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEFMANVGGLL 1148
>gi|223941912 coiled-coil domain containing 135 [Homo sapiens]
Length = 874
Score = 35.8 bits (81), Expect = 0.90
Identities = 23/58 (39%), Positives = 31/58 (53%), Gaps = 10/58 (17%)
Query: 2547 SPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHPLSECEFQEYTIDSDWRFRSTVLTP 2604
+PK E H L +A NF + + + PD P+F HPL+ECE +F ST L P
Sbjct: 88 TPK-EEHLLQVADNFSRQYSHLCPDRV-PLFLHPLNECEVP--------KFVSTTLRP 135
>gi|188497683 FAST kinase domains 1 [Homo sapiens]
Length = 847
Score = 35.4 bits (80), Expect = 1.2
Identities = 31/143 (21%), Positives = 67/143 (46%), Gaps = 26/143 (18%)
Query: 280 SQFSTCLLDNYVSLFEVLLKWC--AHTNVELKKAALSALESFLKQVSNMVAKNAEMHK-N 336
S+FS+CL D ++ ++ K H N+E + LS+L + +S++++++ + N
Sbjct: 156 SEFSSCLADQHLYFSPLMGKIADIVHRNLETTQD-LSSLSVLMVNISSLISRHFQQQLVN 214
Query: 337 KLQYFMEQFYGIIRNVDSNNKELSIAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMF 396
K + + +DS+ ++ +I + ++V + Y L++RC +F
Sbjct: 215 KTELLFD-------TIDSSEVNVAKSIAKF-----------LRNVRYRYQPLLERCNNVF 256
Query: 397 LTQTDTGD----DRVYQMPSFLQ 415
L+ D D ++ + FLQ
Sbjct: 257 LSNVDHLDLDSISKILSVYKFLQ 279
>gi|41352697 centromere protein I [Homo sapiens]
Length = 756
Score = 34.3 bits (77), Expect = 2.6
Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 8/72 (11%)
Query: 822 AQKGFNKVVLKHLKKTKNLSSNEAISLEEIRIRV-VQMLGSLGGQINKNLL------TVT 874
A + +K + KHLK +N++ ++ EEI I + + + G G +N +L TV
Sbjct: 80 ASQNKDKTLEKHLKTVENVAWKNGLASEEIDILLNIALSGKFGNAVNTRILKCMIPATVI 139
Query: 875 SSDEMMKSYVAW 886
S D ++K+ V+W
Sbjct: 140 SEDSVVKA-VSW 150
>gi|122937502 transmembrane channel-like 3 [Homo sapiens]
Length = 1100
Score = 33.9 bits (76), Expect = 3.4
Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 11/95 (11%)
Query: 2093 CMAPLTALVKHMHRSL--GPPQGEE-------DSVPRDLPSWMKFLHGKLGNPIVPLNIR 2143
CM P + SL GP G+E +++ +D P W + G + +P+V L
Sbjct: 631 CMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGSVVGHISSPVVILPAV 690
Query: 2144 LFLAKLVINTEEVFR--PYAKHWLSPLLQLAASEN 2176
L L L+ + + R + H L +Q A SE+
Sbjct: 691 LLLFMLIYYLQSIARSLKLSNHQLKMQIQNARSED 725
>gi|27734911 DAZ interacting protein 1-like [Homo sapiens]
Length = 767
Score = 33.1 bits (74), Expect = 5.9
Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 8/56 (14%)
Query: 3740 IRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGIL--------AQDSACSQRALQ 3787
+RGH +R H + +GG+ +Q+Q VE++ + + L AQ A QR LQ
Sbjct: 181 LRGHIQRRHAGVAEGGKQKKQEQPVEEVLEELRAKLKWTQGELEAQREAERQRQLQ 236
>gi|4505807 phosphatidylinositol 4-kinase type 3 alpha isoform 1 [Homo
sapiens]
Length = 854
Score = 32.7 bits (73), Expect = 7.7
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 3896 AFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSA 3949
AF R +F S A + ++L I DRH N M+ + G +I IDFG F S+
Sbjct: 683 AFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLD-KKGHIIHIDFGFMFESS 735
>gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform 2
[Homo sapiens]
Length = 2044
Score = 32.7 bits (73), Expect = 7.7
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 3896 AFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSA 3949
AF R +F S A + ++L I DRH N M+ + G +I IDFG F S+
Sbjct: 1873 AFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLD-KKGHIIHIDFGFMFESS 1925
>gi|12083581 phosphoinositide-specific phospholipase C beta 1 isoform
a [Homo sapiens]
Length = 1216
Score = 32.7 bits (73), Expect = 7.7
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 11/201 (5%)
Query: 1833 LDALREFFSTIVVDAIDVLKSRFTKLNESTFDTQITKKMGYYKILDVMYSRLPKDDVHAK 1892
L AL + ++D D + + L + + ++ +K + K+L + + ++ + +
Sbjct: 994 LAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQ 1053
Query: 1893 ESKINQVFHGSCITEGNELTKTLIKLCYDAFTENMAGENQLLERRRLYHCAAYNCAISVI 1952
K+ ++ C E EL K + K + TE + + +E + +Y I +
Sbjct: 1054 LKKLKEI----CEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSY---IQEV 1106
Query: 1953 CCVFNELKFYQGFLFSEKPEKNLLIFENLIDLKRRYNFPVEVEVPMERKKKYIEIRKEAR 2012
L+ Q + EK+ I + ++D K + +E E + K+ +EI + +
Sbjct: 1107 VQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEILEFVQ 1166
Query: 2013 EAANG----DSDGPSYMSSLS 2029
EA G DS+ S SLS
Sbjct: 1167 EAMKGKISEDSNHGSAPLSLS 1187
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 151,188,848
Number of Sequences: 37866
Number of extensions: 6716197
Number of successful extensions: 16502
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 16300
Number of HSP's gapped (non-prelim): 171
length of query: 4128
length of database: 18,247,518
effective HSP length: 123
effective length of query: 4005
effective length of database: 13,590,000
effective search space: 54427950000
effective search space used: 54427950000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.