Guide to the Human Genome
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Name: SERGEF Sequence: fasta or formatted (458aa) NCBI GI: 6912330
Description:

deafness locus associated putative guanine nucleotide exchange factor

Referenced in:

Ran and Rag

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.2         42           4
 C cysteine            4.1         19           1
 D aspartate           3.7         17           1
 E glutamate           5.9         27           1
 F phenylalanine       3.1         14           2
 G glycine            11.4         52           4
 H histidine           3.3         15           1
 I isoleucine          2.6         12           2
 K lysine              4.4         20           1
 L leucine             9.2         42           2
 M methionine          1.5          7           1
 N asparagine          3.3         15           1
 P proline             5.7         26           2
 Q glutamine           5.2         24           2
 R arginine            3.5         16           2
 S serine              8.1         37           3
 T threonine           5.5         25           1
 V valine              6.1         28           2
 W tryptophan          2.8         13           1
 Y tyrosine            1.5          7           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   deafness locus associated putative guanine nucleotide... 
HERC3                 0.131   hect domain and RLD 3 
HERC4                 0.128   hect domain and RLD 4 isoform b 
HERC4                 0.128   hect domain and RLD 4 isoform a 
HERC2                 0.116   hect domain and RLD 2 
HERC1                 0.104   guanine nucleotide exchange factor p532 
RPGR                  0.100   retinitis pigmentosa GTPase regulator isoform A [Homo...
RPGR                  0.100   retinitis pigmentosa GTPase regulator isoform C [Hom...
HERC6                 0.085   hect domain and RLD 6 
RCBTB2                0.084   regulator of chromosome condensation and BTB domain c...
RCBTB1                0.083   regulator of chromosome condensation (RCC1) and BTB ...
RCC1                  0.077   regulator of chromosome condensation 1 isoform b [H...
RCC1                  0.077   regulator of chromosome condensation 1 isoform a [H...
RCC1                  0.077   regulator of chromosome condensation 1 isoform c [Hom...
SNHG3-RCC1            0.077   regulator of chromosome condensation 1 
SNHG3-RCC1            0.077   regulator of chromosome condensation 1 
SNHG3-RCC1            0.077   regulator of chromosome condensation 1 
HERC5                 0.073   hect domain and RLD 5 
RCC2                  0.069   regulator of chromosome condensation 2 
RCC2                  0.069   regulator of chromosome condensation 2 
NEK9                  0.065   NIMA-related kinase 9 
NEK8                  0.064   NIMA-related kinase 8 
WBSCR16               0.059   Williams-Beuren syndrome chromosome region 16 
LOC390561             0.058   PREDICTED: similar to hect domain and RLD 2 
LOC390561             0.056   PREDICTED: similar to hect domain and RLD 2 
LOC653375             0.055   PREDICTED: RCC1-like G exchanging factor-like [Homo...
LOC653375             0.055   PREDICTED: RCC1-like G exchanging factor-like [Homo...
LOC100290629          0.052   PREDICTED: hypothetical protein XP_002347563 
IBTK                  0.051   inhibitor of Bruton's tyrosine kinase 
RCCD1                 0.045   RCC1 domain containing 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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