Guide to the Human Genome
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Name: HERC2 Sequence: fasta or formatted (4834aa) NCBI GI: 126032348
Description:

hect domain and RLD 2

Referenced in:

Ran and Rag
Ubiquitin and Related Protein Modifications

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.8        379           3
 C cysteine            2.4        116           2
 D aspartate           5.8        281           3
 E glutamate           6.2        298           4
 F phenylalanine       2.6        128           2
 G glycine             8.2        396           3
 H histidine           2.5        122           2
 I isoleucine          4.5        219           2
 K lysine              5.0        241           2
 L leucine            11.3        547           4
 M methionine          1.8         85           2
 N asparagine          2.8        133           2
 P proline             4.8        234           3
 Q glutamine           4.4        214           2
 R arginine            5.3        255           4
 S serine              8.5        413           4
 T threonine           5.3        254           3
 V valine              7.3        354           3
 W tryptophan          1.6         78           1
 Y tyrosine            1.8         87           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hect domain and RLD 2 
HERC1                 0.068   guanine nucleotide exchange factor p532 
LOC390561             0.063   PREDICTED: similar to hect domain and RLD 2 
LOC100290629          0.063   PREDICTED: hypothetical protein XP_002347563 
LOC390561             0.063   PREDICTED: similar to hect domain and RLD 2 
HERC4                 0.017   hect domain and RLD 4 isoform b 
HERC4                 0.017   hect domain and RLD 4 isoform a 
HECTD3                0.017   HECT domain containing 3 
HERC3                 0.016   hect domain and RLD 3 
LOC100289574          0.015   PREDICTED: hypothetical protein XP_002343479 
C12orf51              0.014   chromosome 12 open reading frame 51 
HERC6                 0.013   hect domain and RLD 6 
RCBTB2                0.013   regulator of chromosome condensation and BTB domain c...
NEK8                  0.013   NIMA-related kinase 8 
RCBTB1                0.012   regulator of chromosome condensation (RCC1) and BTB ...
HERC5                 0.012   hect domain and RLD 5 
ITCH                  0.012   itchy homolog E3 ubiquitin protein ligase 
NEK9                  0.012   NIMA-related kinase 9 
SMURF2                0.011   SMAD specific E3 ubiquitin protein ligase 2 
WWP1                  0.011   WW domain containing E3 ubiquitin protein ligase 1 [...
SERGEF                0.011   deafness locus associated putative guanine nucleotide...
HUWE1                 0.011   HECT, UBA and WWE domain containing 1 
HACE1                 0.011   HECT domain and ankyrin repeat containing, E3 ubiqu...
RCC2                  0.011   regulator of chromosome condensation 2 
RCC2                  0.011   regulator of chromosome condensation 2 
RPGR                  0.011   retinitis pigmentosa GTPase regulator isoform A [Homo...
RPGR                  0.011   retinitis pigmentosa GTPase regulator isoform C [Hom...
SMURF1                0.011   Smad ubiquitination regulatory factor 1 isoform 1 [H...
SMURF1                0.011   Smad ubiquitination regulatory factor 1 isoform 2 [H...
WWP2                  0.011   WW domain containing E3 ubiquitin protein ligase 2 i...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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