Guide to the Human Genome
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Name: HERC4 Sequence: fasta or formatted (1057aa) NCBI GI: 63025188
Description:

hect domain and RLD 4 isoform a

Referenced in:

Ran and Rag
Ubiquitin and Related Protein Modifications

Other entries for this name:
alt prot [1049aa] hect domain and RLD 4 isoform b
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.0         53           2
 C cysteine            2.4         25           2
 D aspartate           5.6         59           2
 E glutamate           6.1         64           2
 F phenylalanine       5.5         58           2
 G glycine             7.9         84           3
 H histidine           2.6         27           1
 I isoleucine          6.1         64           2
 K lysine              6.2         66           3
 L leucine            11.4        120           3
 M methionine          1.5         16           1
 N asparagine          4.8         51           2
 P proline             4.4         46           2
 Q glutamine           4.5         48           3
 R arginine            3.5         37           2
 S serine              6.2         66           3
 T threonine           4.6         49           2
 V valine              7.0         74           3
 W tryptophan          1.3         14           2
 Y tyrosine            3.4         36           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hect domain and RLD 4 isoform a 
HERC4                 0.989   hect domain and RLD 4 isoform b 
HERC3                 0.540   hect domain and RLD 3 
HERC6                 0.294   hect domain and RLD 6 
HERC5                 0.286   hect domain and RLD 5 
HECTD2                0.131   HECT domain containing 2 isoform a 
UBE3A                 0.128   ubiquitin protein ligase E3A isoform 3 
UBE3A                 0.128   ubiquitin protein ligase E3A isoform 1 
UBE3A                 0.128   ubiquitin protein ligase E3A isoform 2 
HERC2                 0.076   hect domain and RLD 2 
HECW2                 0.073   HECT, C2 and WW domain containing E3 ubiquitin prote...
WWP2                  0.072   WW domain containing E3 ubiquitin protein ligase 2 i...
WWP2                  0.072   WW domain containing E3 ubiquitin protein ligase 2 i...
NEDD4L                0.071   neural precursor cell expressed, developmentally do...
NEDD4L                0.071   neural precursor cell expressed, developmentally dow...
NEDD4L                0.071   neural precursor cell expressed, developmentally do...
NEDD4L                0.071   neural precursor cell expressed, developmentally do...
NEDD4L                0.071   neural precursor cell expressed, developmentally do...
NEDD4L                0.071   neural precursor cell expressed, developmentally do...
NEDD4L                0.071   neural precursor cell expressed, developmentally do...
NEDD4L                0.071   neural precursor cell expressed, developmentally do...
NEDD4L                0.071   neural precursor cell expressed, developmentally do...
SMURF2                0.071   SMAD specific E3 ubiquitin protein ligase 2 
HECW1                 0.071   NEDD4-like ubiquitin-protein ligase 1 
SMURF1                0.071   Smad ubiquitination regulatory factor 1 isoform 1 [H...
SMURF1                0.071   Smad ubiquitination regulatory factor 1 isoform 2 [H...
ITCH                  0.069   itchy homolog E3 ubiquitin protein ligase 
NEDD4                 0.068   neural precursor cell expressed, developmentally do...
NEDD4                 0.068   neural precursor cell expressed, developmentally do...
HERC1                 0.068   guanine nucleotide exchange factor p532 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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