IBTK 33456

Name: IBTK	Sequence: fasta or formatted (1353aa)		NCBI GI: 57863304
Description: inhibitor of Bruton's tyrosine kinase		Referenced in: Ran and Rag Non-Receptor Tyrosine Kinase Pathways
Composition: Amino acid Percentage Count Longest homopolymer A alanine 5.6 76 3 C cysteine 2.5 34 1 D aspartate 5.6 76 2 E glutamate 6.0 81 3 F phenylalanine 4.2 57 2 G glycine 6.0 81 2 H histidine 3.4 46 2 I isoleucine 5.0 67 2 K lysine 8.1 109 3 L leucine 9.5 129 2 M methionine 1.9 26 1 N asparagine 4.1 55 2 P proline 4.5 61 3 Q glutamine 3.7 50 2 R arginine 3.8 51 2 S serine 10.3 139 4 T threonine 4.9 66 2 V valine 7.5 101 2 W tryptophan 1.0 14 1 Y tyrosine 2.5 34 1			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 inhibitor of Bruton's tyrosine kinase HERC2 0.025 hect domain and RLD 2 HERC3 0.024 hect domain and RLD 3 HERC1 0.022 guanine nucleotide exchange factor p532 HERC4 0.022 hect domain and RLD 4 isoform b HERC4 0.022 hect domain and RLD 4 isoform a HERC5 0.021 hect domain and RLD 5 RCC2 0.020 regulator of chromosome condensation 2 RCC2 0.020 regulator of chromosome condensation 2 RCBTB2 0.018 regulator of chromosome condensation and BTB domain c... KLHL11 0.018 kelch-like 11 SERGEF 0.018 deafness locus associated putative guanine nucleotide... LOC390561 0.017 PREDICTED: similar to hect domain and RLD 2 SPOP 0.017 speckle-type POZ protein SPOP 0.017 speckle-type POZ protein SPOP 0.017 speckle-type POZ protein SPOP 0.017 speckle-type POZ protein SPOP 0.017 speckle-type POZ protein SPOP 0.017 speckle-type POZ protein LOC100290629 0.017 PREDICTED: hypothetical protein XP_002347563 NEK8 0.017 NIMA-related kinase 8 LOC390561 0.016 PREDICTED: similar to hect domain and RLD 2 KLHL10 0.016 kelch-like 10 MYCBP2 0.016 MYC binding protein 2 NEK9 0.016 NIMA-related kinase 9 KBTBD6 0.016 kelch repeat and BTB (POZ) domain-containing 6 [Homo... KLHL6 0.015 kelch-like 6 SPOPL 0.015 speckle-type POZ protein-like RPGR 0.014 retinitis pigmentosa GTPase regulator isoform A [Homo... RPGR 0.014 retinitis pigmentosa GTPase regulator isoform C [Hom... Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.