Guide to the Human Genome
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Name: HERC1 Sequence: fasta or formatted (4861aa) NCBI GI: 126131099
Description:

guanine nucleotide exchange factor p532

Referenced in:

Ran and Rag
Ubiquitin and Related Protein Modifications

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.4        358           3
 C cysteine            2.5        121           2
 D aspartate           5.1        248           2
 E glutamate           6.7        328           4
 F phenylalanine       2.3        112           2
 G glycine             7.7        375           3
 H histidine           2.7        132           2
 I isoleucine          3.8        185           2
 K lysine              4.3        210           2
 L leucine            11.5        560           4
 M methionine          2.4        116           2
 N asparagine          3.1        151           2
 P proline             4.8        234           4
 Q glutamine           5.0        241           3
 R arginine            5.2        255           2
 S serine              9.9        479           3
 T threonine           5.3        256           3
 V valine              6.6        322           3
 W tryptophan          1.6         76           2
 Y tyrosine            2.1        102           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   guanine nucleotide exchange factor p532 
HERC2                 0.068   hect domain and RLD 2 
HECTD3                0.018   HECT domain containing 3 
HERC3                 0.016   hect domain and RLD 3 
HERC4                 0.015   hect domain and RLD 4 isoform b 
HERC4                 0.015   hect domain and RLD 4 isoform a 
RCBTB2                0.013   regulator of chromosome condensation and BTB domain c...
C12orf51              0.013   chromosome 12 open reading frame 51 
HERC6                 0.013   hect domain and RLD 6 
RPGR                  0.013   retinitis pigmentosa GTPase regulator isoform A [Homo...
RPGR                  0.013   retinitis pigmentosa GTPase regulator isoform C [Hom...
NEDD4                 0.012   neural precursor cell expressed, developmentally do...
NEDD4                 0.012   neural precursor cell expressed, developmentally do...
SMURF2                0.012   SMAD specific E3 ubiquitin protein ligase 2 
RCBTB1                0.012   regulator of chromosome condensation (RCC1) and BTB ...
ITCH                  0.012   itchy homolog E3 ubiquitin protein ligase 
HUWE1                 0.012   HECT, UBA and WWE domain containing 1 
HERC5                 0.012   hect domain and RLD 5 
SMURF1                0.012   Smad ubiquitination regulatory factor 1 isoform 1 [H...
SMURF1                0.012   Smad ubiquitination regulatory factor 1 isoform 2 [H...
LOC100290629          0.012   PREDICTED: hypothetical protein XP_002347563 
HACE1                 0.012   HECT domain and ankyrin repeat containing, E3 ubiqu...
LOC390561             0.011   PREDICTED: similar to hect domain and RLD 2 
WWP2                  0.011   WW domain containing E3 ubiquitin protein ligase 2 i...
WWP2                  0.011   WW domain containing E3 ubiquitin protein ligase 2 i...
LOC390561             0.011   PREDICTED: similar to hect domain and RLD 2 
NEK9                  0.011   NIMA-related kinase 9 
NEDD4L                0.011   neural precursor cell expressed, developmentally do...
NEDD4L                0.011   neural precursor cell expressed, developmentally dow...
NEDD4L                0.011   neural precursor cell expressed, developmentally do...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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