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Search of human proteins with 68163411
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|68163411 activated leukocyte cell adhesion molecule [Homo
sapiens]
(583 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|68163411 activated leukocyte cell adhesion molecule [Homo sap... 1172 0.0
gi|71274107 melanoma cell adhesion molecule [Homo sapiens] 174 2e-43
gi|61742797 basal cell adhesion molecule isoform 2 precursor [Ho... 154 2e-37
gi|31543106 basal cell adhesion molecule isoform 1 precursor [Ho... 154 2e-37
gi|10835203 advanced glycosylation end product-specific receptor... 82 1e-15
gi|26787962 advanced glycosylation end product-specific receptor... 79 2e-14
gi|118572606 hemicentin 1 [Homo sapiens] 79 2e-14
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens] 76 7e-14
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens] 75 1e-13
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens] 75 2e-13
gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens] 72 2e-12
gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens] 72 2e-12
gi|21686977 cell adhesion molecule 4 [Homo sapiens] 69 1e-11
gi|166295173 kin of IRRE like [Homo sapiens] 67 3e-11
gi|98986445 carcinoembryonic antigen-related cell adhesion molec... 67 6e-11
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho... 66 1e-10
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho... 66 1e-10
gi|109150416 peroxidasin [Homo sapiens] 66 1e-10
gi|4507875 vascular cell adhesion molecule 1 isoform a precursor... 60 6e-09
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 60 6e-09
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 60 6e-09
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 60 6e-09
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 59 2e-08
gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo sap... 59 2e-08
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap... 59 2e-08
gi|18201909 vascular cell adhesion molecule 1 isoform b precurso... 58 3e-08
gi|221316762 neurotrimin isoform 4 [Homo sapiens] 57 5e-08
gi|221316757 neurotrimin isoform 3 [Homo sapiens] 57 5e-08
gi|115298665 neurotrimin isoform 2 [Homo sapiens] 57 5e-08
gi|7705413 neurotrimin isoform 1 [Homo sapiens] 57 5e-08
>gi|68163411 activated leukocyte cell adhesion molecule [Homo
sapiens]
Length = 583
Score = 1172 bits (3033), Expect = 0.0
Identities = 583/583 (100%), Positives = 583/583 (100%)
Query: 1 MESKGASSCRLLFCLLISATVFRPGLGWYTVNSAYGDTIIIPCRLDVPQNLMFGKWKYEK 60
MESKGASSCRLLFCLLISATVFRPGLGWYTVNSAYGDTIIIPCRLDVPQNLMFGKWKYEK
Sbjct: 1 MESKGASSCRLLFCLLISATVFRPGLGWYTVNSAYGDTIIIPCRLDVPQNLMFGKWKYEK 60
Query: 61 PDGSPVFIAFRSSTKKSVQYDDVPEYKDRLNLSENYTLSISNARISDEKRFVCMLVTEDN 120
PDGSPVFIAFRSSTKKSVQYDDVPEYKDRLNLSENYTLSISNARISDEKRFVCMLVTEDN
Sbjct: 61 PDGSPVFIAFRSSTKKSVQYDDVPEYKDRLNLSENYTLSISNARISDEKRFVCMLVTEDN 120
Query: 121 VFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPL 180
VFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPL
Sbjct: 121 VFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPL 180
Query: 181 EGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVF 240
EGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVF
Sbjct: 181 EGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVF 240
Query: 241 DIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTL 300
DIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTL
Sbjct: 241 DIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTL 300
Query: 301 TDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASR 360
TDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASR
Sbjct: 301 TDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASR 360
Query: 361 NATVVWMKDNIRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKM 420
NATVVWMKDNIRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKM
Sbjct: 361 NATVVWMKDNIRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKM 420
Query: 421 TKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEEN 480
TKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEEN
Sbjct: 421 TKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEEN 480
Query: 481 VTLTCTAENQLERTVNSLNVSAISIPEHDEADEISDENREKVNDQAKLIVGIVVGLLLAA 540
VTLTCTAENQLERTVNSLNVSAISIPEHDEADEISDENREKVNDQAKLIVGIVVGLLLAA
Sbjct: 481 VTLTCTAENQLERTVNSLNVSAISIPEHDEADEISDENREKVNDQAKLIVGIVVGLLLAA 540
Query: 541 LVAGVVYWLYMKKSKTASKHVNKDLGNMEENKKLEENNHKTEA 583
LVAGVVYWLYMKKSKTASKHVNKDLGNMEENKKLEENNHKTEA
Sbjct: 541 LVAGVVYWLYMKKSKTASKHVNKDLGNMEENKKLEENNHKTEA 583
>gi|71274107 melanoma cell adhesion molecule [Homo sapiens]
Length = 646
Score = 174 bits (441), Expect = 2e-43
Identities = 143/583 (24%), Positives = 260/583 (44%), Gaps = 59/583 (10%)
Query: 36 GDTIIIPCRLDVPQ-NLMFGKWKYEKPDGSPVFIAFRSSTKKSVQYDDVPEYKDRLNLSE 94
G T ++ C L Q NL W + + R +S + EY+ RL+L +
Sbjct: 41 GSTALLKCGLSQSQGNLSHVDWFSVHKEKRTLIFRVRQGQGQS----EPGEYEQRLSLQD 96
Query: 95 N-YTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFL--ETEQL 151
TL+++ DE+ F+C E ++V+K P +P I L + +++
Sbjct: 97 RGATLALTQVTPQDERIFLCQ-GKRPRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEP 155
Query: 152 KKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTK 211
+++ C+ + YP + WY+NG+ L + V I + ++ + LYT+ S L+ + K
Sbjct: 156 EEVATCVGRNGYPIPQVIWYKNGRPLKEEKNRVHIQSSQTVES-SGLYTLQSILKAQLVK 214
Query: 212 ADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCL 271
D F C + Y PSG S + ++YPTE+V ++V P +KEGD + ++CL
Sbjct: 215 EDKDAQFYCELNYRLPSGNHMKESREVTVPVFYPTEKVWLEV-EPVGMLKEGDRVEIRCL 273
Query: 272 GNGNPPPEEFLFYLPGQPEGIRSSNTYTLTD--------VRRNATGDYKCSLIDKKSMIA 323
+GNPPP F + Q R + T D R+ +G Y+C +D +MI+
Sbjct: 274 ADGNPPPH---FSISKQNPSTREAEEETTNDNGVLVLEPARKEHSGRYECQGLDLDTMIS 330
Query: 324 STA----ITVHYL-DLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIR--LRSS 376
+ + V+Y+ D+ ++P+ RQ G +L ++C +S++ W+++ L
Sbjct: 331 LLSEPQELLVNYVSDVRVSPAAP-ERQEGSSLTLTCEAESSQDLEFQWLREETGQVLERG 389
Query: 377 P--SFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKP--QIKMTKKTDPSGLSKT 432
P L + G Y C ++ + GL + + + + + G P K K +
Sbjct: 390 PVLQLHDLKREAGGGYRCVASVPSIPGLNRTQLVNVAIFGPPWMAFKERKVWVKENMVLN 449
Query: 433 IICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVT-LTCTAENQL 491
+ C G P+P I W + G+ S +Q + ++++PE T + CTA N L
Sbjct: 450 LSCEASGHPRPTISWNVNGTASEQDQDPQRVLST----LNVLVTPELLETGVECTASNDL 505
Query: 492 ERTVNSL------------------NVSAISIPEHDEADEISDENR-EKVNDQAKLIVGI 532
+ + L +S + H A+ S E + + + +IV +
Sbjct: 506 GKNTSILFLELVNLTTLTPDSNTTTGLSTSTASPHTRANSTSTERKLPEPESRGVVIVAV 565
Query: 533 VVGLLLAALVAGVVYWLYMKKSKTASKHVNKDLGNMEENKKLE 575
+V +L+ A++ V+Y+LY KK K + K + ++K E
Sbjct: 566 IVCILVLAVLGAVLYFLY-KKGKLPCRRSGKQEITLPPSRKSE 607
>gi|61742797 basal cell adhesion molecule isoform 2 precursor [Homo
sapiens]
Length = 588
Score = 154 bits (389), Expect = 2e-37
Identities = 133/484 (27%), Positives = 216/484 (44%), Gaps = 48/484 (9%)
Query: 98 LSISNARISDEKRFVCML-VTEDNVFEAPTIVKVFKQPSKPEIVSK--ALFLETEQLKKL 154
L ++ A++ DE+ +VC++ EA + VF +P E+ L + + +++
Sbjct: 110 LVLAEAQVGDERDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPNKGTLSVMEDSAQEI 169
Query: 155 GDCISEDSYPDGNITWYRNGKVLH-PLE-GAVVIIFKKEMDPVTQLYTMTSTLEYKTTKA 212
C S + P ITWYRNG+ L P+E + + + + L ++TSTL + K
Sbjct: 170 ATCNSRNGNPAPKITWYRNGQRLEVPVEMNPEGYMTSRTVREASGLLSLTSTLYLRLRKD 229
Query: 213 DIQMPFTCSVTYYGPSGQK-TIHSEQAVFDIYYPTEQVTIQVLPPKNA---IKEGDNITL 268
D F C+ Y P G+ + S ++YPTE V V P ++EGD + L
Sbjct: 230 DRDASFHCAAHYSLPEGRHGRLDSPTFHLTLHYPTEHVQFWVGSPSTPAGWVREGDTVQL 289
Query: 269 KCLGNGNPPPEEFLFYLPGQPEGIRSSN---TYTLTDVRRNATGDYKCSL-----IDKKS 320
C G+G+P PE LF L + E + + N TL V R +G Y C + D
Sbjct: 290 LCRGDGSPSPEYTLFRLQDEQEEVLNVNLEGNLTLEGVTRGQSGTYGCRVEDYDAADDVQ 349
Query: 321 MIASTAITVHYLD-LSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSSP-- 377
+ + + V YLD L L+ ++ + + V+C++ + W KD+ L P
Sbjct: 350 LSKTLELRVAYLDPLELSEGKVLSLPLNSSAVVNCSVHGLPTPALRWTKDSTPLGDGPML 409
Query: 378 SFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTK---KTDPS---GLSK 431
S SS+ + G YVCE +L V L + ++ TL+V+G P++K + K D S G
Sbjct: 410 SLSSITFDSNGTYVCEASLPTVPVLSRTQNFTLLVQGSPELKTAEIEPKADGSWREGDEV 469
Query: 432 TIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVT---LTCTAE 488
T+IC G P P + W+ G + E P G S + + ++ ++C A
Sbjct: 470 TLICSARGHPDPKLSWSQLGG----SPAEPIPGRQGWVSSSLTLKVTSALSRDGISCEAS 525
Query: 489 NQLERTVNSLNVSAISIPEHDEADEISDENREKVNDQAKLIVGIVVGLLLAALVAGVVYW 548
N + + +S P+ +A A + V + VGLLL LV V Y
Sbjct: 526 NPHGNKRHVFHFGTVS-PQTSQA------------GVAVMAVAVSVGLLL--LVVAVFYC 570
Query: 549 LYMK 552
+ K
Sbjct: 571 VRRK 574
>gi|31543106 basal cell adhesion molecule isoform 1 precursor [Homo
sapiens]
Length = 628
Score = 154 bits (389), Expect = 2e-37
Identities = 133/484 (27%), Positives = 216/484 (44%), Gaps = 48/484 (9%)
Query: 98 LSISNARISDEKRFVCML-VTEDNVFEAPTIVKVFKQPSKPEIVSK--ALFLETEQLKKL 154
L ++ A++ DE+ +VC++ EA + VF +P E+ L + + +++
Sbjct: 110 LVLAEAQVGDERDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPNKGTLSVMEDSAQEI 169
Query: 155 GDCISEDSYPDGNITWYRNGKVLH-PLE-GAVVIIFKKEMDPVTQLYTMTSTLEYKTTKA 212
C S + P ITWYRNG+ L P+E + + + + L ++TSTL + K
Sbjct: 170 ATCNSRNGNPAPKITWYRNGQRLEVPVEMNPEGYMTSRTVREASGLLSLTSTLYLRLRKD 229
Query: 213 DIQMPFTCSVTYYGPSGQK-TIHSEQAVFDIYYPTEQVTIQVLPPKNA---IKEGDNITL 268
D F C+ Y P G+ + S ++YPTE V V P ++EGD + L
Sbjct: 230 DRDASFHCAAHYSLPEGRHGRLDSPTFHLTLHYPTEHVQFWVGSPSTPAGWVREGDTVQL 289
Query: 269 KCLGNGNPPPEEFLFYLPGQPEGIRSSN---TYTLTDVRRNATGDYKCSL-----IDKKS 320
C G+G+P PE LF L + E + + N TL V R +G Y C + D
Sbjct: 290 LCRGDGSPSPEYTLFRLQDEQEEVLNVNLEGNLTLEGVTRGQSGTYGCRVEDYDAADDVQ 349
Query: 321 MIASTAITVHYLD-LSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSSP-- 377
+ + + V YLD L L+ ++ + + V+C++ + W KD+ L P
Sbjct: 350 LSKTLELRVAYLDPLELSEGKVLSLPLNSSAVVNCSVHGLPTPALRWTKDSTPLGDGPML 409
Query: 378 SFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTK---KTDPS---GLSK 431
S SS+ + G YVCE +L V L + ++ TL+V+G P++K + K D S G
Sbjct: 410 SLSSITFDSNGTYVCEASLPTVPVLSRTQNFTLLVQGSPELKTAEIEPKADGSWREGDEV 469
Query: 432 TIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVT---LTCTAE 488
T+IC G P P + W+ G + E P G S + + ++ ++C A
Sbjct: 470 TLICSARGHPDPKLSWSQLGG----SPAEPIPGRQGWVSSSLTLKVTSALSRDGISCEAS 525
Query: 489 NQLERTVNSLNVSAISIPEHDEADEISDENREKVNDQAKLIVGIVVGLLLAALVAGVVYW 548
N + + +S P+ +A A + V + VGLLL LV V Y
Sbjct: 526 NPHGNKRHVFHFGTVS-PQTSQA------------GVAVMAVAVSVGLLL--LVVAVFYC 570
Query: 549 LYMK 552
+ K
Sbjct: 571 VRRK 574
>gi|10835203 advanced glycosylation end product-specific receptor
isoform 1 precursor [Homo sapiens]
Length = 404
Score = 82.0 bits (201), Expect = 1e-15
Identities = 65/223 (29%), Positives = 100/223 (44%), Gaps = 6/223 (2%)
Query: 95 NYTLSISNARISDEKRFVCMLVTEDNVFEAPTI-VKVFKQPSKPEIVSKALFLETEQLKK 153
N +L + I DE F C + + V+V++ P KPEIV A L K
Sbjct: 81 NGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQIPGKPEIVDSASELTAGVPNK 140
Query: 154 LGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTK-A 212
+G C+SE SYP G ++W+ +GK L P E V + + P T L+T+ S L +
Sbjct: 141 VGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRHPETGLFTLQSELMVTPARGG 200
Query: 213 DIQMPFTCSVTYYGPSGQ--KTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKC 270
D + F+CS + P + +T + V++ P E+V + V P A+ G +TL C
Sbjct: 201 DPRPTFSCSFSPGLPRHRALRTAPIQPRVWE-PVPLEEVQLVVEPEGGAVAPGGTVTLTC 259
Query: 271 LGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKC 313
P P + + G P + S L ++ G Y C
Sbjct: 260 EVPAQPSP-QIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYSC 301
Score = 36.6 bits (83), Expect = 0.065
Identities = 42/157 (26%), Positives = 60/157 (38%), Gaps = 17/157 (10%)
Query: 428 GLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKII--ISPEENVTLTC 485
G + T+ C V P P I W G V SP + I+ I P++ T +C
Sbjct: 252 GGTVTLTCEVPAQPSPQIHWMKDG---VPLPLPPSPVL-------ILPEIGPQDQGTYSC 301
Query: 486 TAENQLERTVNSLNVSAISIPEHDEADEISDENREKVNDQAKLIVGIVVGLLLAALVAGV 545
A + S VS I +E + A L +GI+ GL AAL+ GV
Sbjct: 302 VATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLA-LALGILGGLGTAALLIGV 360
Query: 546 VYWLYMKKSKTASKHVNKDLGNMEENKKLEENNHKTE 582
+ W + + K N EE ++ E N E
Sbjct: 361 ILW----QRRQRRGEERKAPENQEEEEERAELNQSEE 393
Score = 31.2 bits (69), Expect = 2.8
Identities = 18/70 (25%), Positives = 30/70 (42%), Gaps = 5/70 (7%)
Query: 327 ITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSSPS----FSSL 382
+ + + L + P G G + ++C + A + + WMKD + L PS +
Sbjct: 233 VPLEEVQLVVEPEGGAVAP-GGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEI 291
Query: 383 HYQDAGNYVC 392
QD G Y C
Sbjct: 292 GPQDQGTYSC 301
>gi|26787962 advanced glycosylation end product-specific receptor
isoform 2 precursor [Homo sapiens]
Length = 342
Score = 78.6 bits (192), Expect = 2e-14
Identities = 58/189 (30%), Positives = 89/189 (47%), Gaps = 5/189 (2%)
Query: 95 NYTLSISNARISDEKRFVCMLVTEDNVFEAPTI-VKVFKQPSKPEIVSKALFLETEQLKK 153
N +L + I DE F C + + V+V++ P KPEIV A L K
Sbjct: 67 NGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQIPGKPEIVDSASELTAGVPNK 126
Query: 154 LGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTK-A 212
+G C+SE SYP G ++W+ +GK L P E V + + P T L+T+ S L +
Sbjct: 127 VGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRHPETGLFTLQSELMVTPARGG 186
Query: 213 DIQMPFTCSVTYYGPSGQ--KTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKC 270
D + F+CS + P + +T + V++ P E+V + V P A+ G +TL C
Sbjct: 187 DPRPTFSCSFSPGLPRHRALRTAPIQPRVWE-PVPLEEVQLVVEPEGGAVAPGGTVTLTC 245
Query: 271 LGNGNPPPE 279
P P+
Sbjct: 246 EVPAQPSPQ 254
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 78.6 bits (192), Expect = 2e-14
Identities = 100/441 (22%), Positives = 171/441 (38%), Gaps = 54/441 (12%)
Query: 90 LNLSENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETE 149
L S + L I+ +SDE + C+ V+ A T V + P ++ + E
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE 535
Query: 150 QLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTS-TLEYK 208
+ IS Y N+TW RN + + E A ++ T+ + +LE K
Sbjct: 536 RAVLTCLIISAVDY---NLTWQRNDRDVRLAEPA-------------RIRTLANLSLELK 579
Query: 209 TTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITL 268
+ K + + C V+ G S S +VF +VT V+P + G +++
Sbjct: 580 SVKFNDAGEYHCMVSSEGGS------SAASVFLTVQEPPKVT--VMPKNQSFTGGSEVSI 631
Query: 269 KCLGNGNPPPE-----EFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIA 323
C G P P+ +F + + S T + + G Y C L +
Sbjct: 632 MCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGC-LASNSAGTD 690
Query: 324 STAITVHYLDLS--LNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSS----- 376
T+ Y++ + E+ +GD + C S V W K ++ LR S
Sbjct: 691 KQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLII 750
Query: 377 -PSFSSLHYQ-----DAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDPS--- 427
P L Q DAG+Y C A+ E + +TL V G P + + + D S
Sbjct: 751 DPLLGLLKIQETQDLDAGDYTC-VAINEAG--RATGKITLDV-GSPPVFIQEPADVSMEI 806
Query: 428 GLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIIS---PEENVTLT 484
G + T+ C+V+G+P+P I+W + + ++ I+ + I + T
Sbjct: 807 GSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYI 866
Query: 485 CTAENQLERTVNSLNVSAISI 505
C AENQ + + V+ +
Sbjct: 867 CEAENQFGKIQSETTVTVTGL 887
Score = 64.7 bits (156), Expect = 2e-10
Identities = 100/481 (20%), Positives = 190/481 (39%), Gaps = 72/481 (14%)
Query: 75 KKSVQYDDVPEYKDRLN--LSENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFK 132
+ S Q D P +D + LS L I N +I+D R+VC+ + + V
Sbjct: 2903 RNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHV 2962
Query: 133 QPSKPEIVSKALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEM 192
PS S+ L + L +S +P +++W +N + + ++
Sbjct: 2963 PPSVIGPKSENLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPI-------------KL 3007
Query: 193 DPVTQLYTMTSTLEYKTTKADIQMPFTC-SVTYYGPSGQK---TIHSEQAVFDIYYPTEQ 248
+ T + TL+ K +TC ++ G S +K T++ ++ D + +E
Sbjct: 3008 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKD--HDSES 3065
Query: 249 VTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQP-------EGIRSSNTYTLT 301
+++ ++EG +++L+C N PPP +Y G+ E + +
Sbjct: 3066 LSVV------NVREGTSVSLECESNAVPPPV-ITWYKNGRMITESTHVEILADGQMLHIK 3118
Query: 302 DVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNPSGE------VTRQIGDALPVSCT 355
+ TG Y C I+ +A +L++ + PS E + I + + ++C
Sbjct: 3119 KAEVSDTGQYVCRAIN----VAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCD 3174
Query: 356 ISASRNATVVWMKDNIRLRSSPSF-------------SSLHYQDAGNYVCETALQEVEGL 402
+ T+ W+K++ R+ +S S + + D+GNY C + +EG
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIAS--NMEG- 3231
Query: 403 KKRESLTLIVEGKPQIKMTK-KTDPS---GLSKTIICHVEGFPKPAIQWTITGSGSVINQ 458
K ++ L ++ P + + +D S G + ++C+ G P P IQW G +
Sbjct: 3232 KAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGE 3291
Query: 459 TEE-SPYINGRYYSKIIISPEENVTLTCTAENQLERTVNSLNVSAISIP----EHDEADE 513
TE NG + + TC A N N++ P DEA++
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEK 3351
Query: 514 I 514
+
Sbjct: 3352 L 3352
Score = 64.3 bits (155), Expect = 3e-10
Identities = 102/433 (23%), Positives = 168/433 (38%), Gaps = 66/433 (15%)
Query: 89 RLNLSENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLET 148
R ++ + TL I NA D + C+ + + ++ + P K + +++
Sbjct: 657 RYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAP-------KLMVVQS 709
Query: 149 EQLKKLGDCI----SEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTST 204
E L LGD P + W++ L P ++ DP+ L + T
Sbjct: 710 ELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLII-------DPLLGLLKIQET 762
Query: 205 LEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGD 264
+ +TC +G+ T + D+ P V IQ P +++ G
Sbjct: 763 QDLDAGD------YTCVAI--NEAGRAT---GKITLDVGSPP--VFIQE-PADVSMEIGS 808
Query: 265 NITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTDVRRNAT----------GDYKCS 314
N+TL C G P P L P R + +++ +R A G Y C
Sbjct: 809 NVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICE 868
Query: 315 LIDKKSMIAS-TAITVHYLDLSL-NPSGEVTRQI-GDALPVSCTISASRNATVV-WMKDN 370
++ I S T +TV L L S V I G L + CT+ A W+K++
Sbjct: 869 AENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNS 928
Query: 371 IRLRSSP-----SFSSLHY-----QDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKM 420
L +P S SLH QD G Y C + V G + + +++V P I+
Sbjct: 929 AMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVAS--NVAGTNNKTT-SVVVHVLPTIQH 985
Query: 421 TKK--TDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISP- 477
++ + G+ T+ C G PKP++ W+ G + T + + G S ++SP
Sbjct: 986 GQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGE---LISTSSAKFSAGADGSLYVVSPG 1042
Query: 478 -EENVTLTCTAEN 489
EE+ CTA N
Sbjct: 1043 GEESGEYVCTATN 1055
Score = 63.5 bits (153), Expect = 5e-10
Identities = 101/472 (21%), Positives = 172/472 (36%), Gaps = 69/472 (14%)
Query: 92 LSENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQL 151
LS L++++A+ISD R+ C+ V + ++V+ P+ L ++ +
Sbjct: 2062 LSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAV 2121
Query: 152 KKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTK 211
+ L D+ P +TW ++G HPL KK P + S L+ + +
Sbjct: 2122 ELL---CQSDAIPPPTLTWLKDG---HPL-------LKK---PGLSISENRSVLKIEDAQ 2165
Query: 212 ADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCL 271
+TC T +K + +I+ P L I EG+ I+L C
Sbjct: 2166 VQDTGRYTCEATNVAGKTEKNYN-----VNIWVPPNIGGSDELTQLTVI-EGNLISLLCE 2219
Query: 272 GNGNPPP--------EEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIA 323
+G PPP L G+ + ++ ++ Y C S +A
Sbjct: 2220 SSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSC----VASNVA 2275
Query: 324 STAITVHYLDLSLNP----SGEVTRQI----GDALPVSCTISASRNATVVWMKDNIRLRS 375
TA + L + + P SG +I G ++ + C + TV WMKD L
Sbjct: 2276 GTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIK 2335
Query: 376 SP-----------SFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKT 424
+ ++H D G YVC V G+ ++ L V P I +
Sbjct: 2336 AKGVEILDEGHILQLKNIHVSDTGRYVCVAV--NVAGMTDKK-YDLSVHAPPSI-IGNHR 2391
Query: 425 DPSGL------SKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPE 478
P + S ++ C G P P+I W G ++ + GR + + E
Sbjct: 2392 SPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTME 2450
Query: 479 ENVTLTCTAENQL--ERTVNSLNVSAISIPEHDEADEISDENREKVNDQAKL 528
+ TC N ER + L+V +P H + ++ + K L
Sbjct: 2451 DAGQYTCVVRNAAGEERKIFGLSV---LVPPHIVGENTLEDVKVKEKQSVTL 2499
Score = 57.0 bits (136), Expect = 5e-08
Identities = 95/455 (20%), Positives = 166/455 (36%), Gaps = 57/455 (12%)
Query: 92 LSENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPS-KPEIVSKALFLETEQ 150
L L + NAR +D+ R+ C + + ++ PS K V+ + +
Sbjct: 1504 LDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS 1563
Query: 151 LKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTT 210
L KL +C + P ITWY++G+ + A+ I D L+ + + T
Sbjct: 1564 LIKL-ECETR-GLPMPAITWYKDGQPIMSSSQALYI------DKGQYLHIPRAQVSDSAT 1615
Query: 211 KADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKC 270
+TC V + +K+ H D+Y P P + ++TL+C
Sbjct: 1616 -------YTCHVANVAGTAEKSFH-----VDVYVPPMIEGNLATPLNKQVVIAHSLTLEC 1663
Query: 271 LGNGNPPPEEFLFYLP-GQP----EGIR---SSNTYTLTDVRRNATGDYKCSLIDKKSMI 322
GNP P L +L G P + IR + + G Y C + +
Sbjct: 1664 KAAGNPSP--ILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVA----TSV 1717
Query: 323 ASTAITVHYLDLSLNPS---GEVTR----QIGDALPVSCTISASRNATVVWMKDNIRLRS 375
A + +D+ + P+ G+ T + + L + C ++ S T++W+KD +
Sbjct: 1718 AGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDE 1777
Query: 376 SPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDP----SGLSK 431
F L + V A GL + + + K + ++T P SGLS+
Sbjct: 1778 RDGFKIL--LNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSE 1835
Query: 432 TII---------CHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVT 482
++ C G P P+I W Q +GR E+
Sbjct: 1836 RVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGR 1895
Query: 483 LTCTAENQLERTVNSLNVSAISIPEHDEADEISDE 517
TC A N T + + P ++A ++ +E
Sbjct: 1896 YTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNE 1930
Score = 55.8 bits (133), Expect = 1e-07
Identities = 84/400 (21%), Positives = 155/400 (38%), Gaps = 57/400 (14%)
Query: 88 DRLNLSEN-YTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFL 146
D +N++ N +TL I A+ISD R+ C+ E V + PS ++ L
Sbjct: 2719 DHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNML 2778
Query: 147 ETEQLKKLGDCI---------SEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQ 197
+T + + D I ++ P +TWY++G HPL + ++
Sbjct: 2779 DTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDG---HPLTSSDKVL---------- 2825
Query: 198 LYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPK 257
+ L+ K + +TC +G+ ++ + V + P + LP +
Sbjct: 2826 ILPGGRVLQIPRAKVEDAGRYTCVAV--NEAGEDSLQYDVRV--LVPPIIKGANSDLPEE 2881
Query: 258 NAIKEGDNITLKCLGNGNPPPEEFLFYLPGQP-------EGIRSSNTYTLTDVRRNATGD 310
+ + ++CL +G+P P + GQP + + + + + + G
Sbjct: 2882 VTVLVNKSALIECLSSGSPAPRN-SWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGR 2940
Query: 311 YKCSLIDKK-SMIASTAITVHYLDLSLNPSGE-VTRQIGDALPVSCTISASRNATVVWMK 368
Y C + S + VH + P E +T + + + ++C +S + W+K
Sbjct: 2941 YVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLK 3000
Query: 369 DN--IRLRSS----PSFSSLH-----YQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQ 417
+ I+L ++ P +L D G Y C A+ + KK+ SLT+ V P
Sbjct: 3001 NEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTC-IAINQAGESKKKFSLTVYV--PPS 3057
Query: 418 IK------MTKKTDPSGLSKTIICHVEGFPKPAIQWTITG 451
IK ++ G S ++ C P P I W G
Sbjct: 3058 IKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNG 3097
Score = 52.8 bits (125), Expect = 9e-07
Identities = 100/477 (20%), Positives = 175/477 (36%), Gaps = 76/477 (15%)
Query: 89 RLNLSENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPS-KPEIVSKALFLE 147
R ++ EN L I +A ++D R++CM ++V PS P + + +
Sbjct: 3759 RYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3818
Query: 148 TEQLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTST--L 205
+ P +I W +NG +L+ +D Y + S+ L
Sbjct: 3819 VQTTL----ACEATGIPKPSINWRKNGHLLN-------------VDQNQNSYRLLSSGSL 3861
Query: 206 EYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDN 265
+ D + C+VT ++T+ +T+QV PP A + D
Sbjct: 3862 VIISPSVDDTATYECTVTNGAGDDKRTV--------------DLTVQV-PPSIADEPTDF 3906
Query: 266 ITLK-------CLGNGNPPP-----EEFLFYLP-GQPEGIRSSNTYTLTDVRRNATGDYK 312
+ K C +G P P + + LP G I SS + + N G Y
Sbjct: 3907 LVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYT 3966
Query: 313 CSLIDKKSMIASTAITVHYLD---LSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKD 369
C + + A +T+H + + PS E+ + + + + C + + + + W K+
Sbjct: 3967 C-VARNAAGSAHRHVTLHVHEPPVIQPQPS-ELHVILNNPILLPCEATGTPSPFITWQKE 4024
Query: 370 NIRLRSS-------PS----FSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQI 418
I + +S PS S +DAG Y+C L K + L V+ P I
Sbjct: 4025 GINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGK---IKLNVQVPPVI 4081
Query: 419 KMTKKTDPSGLSK--TIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIIS 476
K + K T+ C +G P P I W G I ++ ++ +
Sbjct: 4082 SPHLKEYVIAVDKPITLSCEADGLPPPDITW--HKDGRAIVESIRQRVLSSGSLQIAFVQ 4139
Query: 477 PEENVTLTCTAENQLERTVNSLNVSAISIPEHDEADEISDENREKVNDQAKLIVGIV 533
P + TC A N + S ++ + +P S E VN+ ++ I+ V
Sbjct: 4140 PGDAGHYTCMAANVAGSSSTSTKLT-VHVPPRIR----STEGHYTVNENSQAILPCV 4191
Score = 52.8 bits (125), Expect = 9e-07
Identities = 60/248 (24%), Positives = 96/248 (38%), Gaps = 31/248 (12%)
Query: 266 ITLKCLGNGNPPPEEFLFYLPGQP--EGIR----SSNTYTLTDVRRNATGDYKCSLIDKK 319
ITL C +G PPP+ ++ G+ E IR SS + + V+ G Y C +
Sbjct: 4096 ITLSCEADGLPPPD-ITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVA 4154
Query: 320 -SMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSSPS 378
S ST +TVH + G T + C + W KDN+ L +
Sbjct: 4155 GSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANL-- 4212
Query: 379 FSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDPS----------- 427
+ G + E + E G + E + +T P+
Sbjct: 4213 LGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLN 4272
Query: 428 -GLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIII---SPEENVTL 483
G + C G P P + WT + ++I +S +NG +S+++I S E++ T
Sbjct: 4273 KGEQLRLSCKATGIPLPKLTWTF--NNNIIPAHFDS--VNG--HSELVIERVSKEDSGTY 4326
Query: 484 TCTAENQL 491
CTAEN +
Sbjct: 4327 VCTAENSV 4334
Score = 52.4 bits (124), Expect = 1e-06
Identities = 81/350 (23%), Positives = 127/350 (36%), Gaps = 66/350 (18%)
Query: 92 LSENYTLSISNARISDEKRFVCMLVT---------EDNVFEAPTIVKVFKQPSKPEIVSK 142
L E + L + N +SD R+VC+ V + +V P+I+ + P +V K
Sbjct: 2342 LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401
Query: 143 ALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMT 202
+ P +ITW+++G + L +V I+ M L M
Sbjct: 2402 ---------NSVSLTCEASGIPLPSITWFKDGWPV-SLSNSVRILSGGRM-----LRLMQ 2446
Query: 203 STLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVF--DIYYPTEQVTIQVLPPKNAI 260
+T+E +TC V + E+ +F + P V L +
Sbjct: 2447 TTMEDAG-------QYTCVV-------RNAAGEERKIFGLSVLVPPHIVGENTLEDVK-V 2491
Query: 261 KEGDNITLKCLGNGNPPPEEFLFYLPGQP-------EGIRSSNTYTLTDVRRNATGDYKC 313
KE ++TL C GNP P E ++ GQP I +T+V+ TG Y C
Sbjct: 2492 KEKQSVTLTCEVTGNPVP-EITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTC 2550
Query: 314 ---SLIDKKSMIASTAITVHYLDLSLNPSG---EVTRQIGDALPVSCTISASRNATVVWM 367
S KS S + V + G +VT + + C + AT+ W
Sbjct: 2551 LASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWF 2610
Query: 368 KDNIRLRSSPSFSSL-----------HYQDAGNYVCETALQEVEGLKKRE 406
KD L S+ + L +AG Y C + E +K E
Sbjct: 2611 KDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660
Score = 48.9 bits (115), Expect = 1e-05
Identities = 57/223 (25%), Positives = 90/223 (40%), Gaps = 27/223 (12%)
Query: 251 IQVLPPKNAIKEGDNITLKC-LGNGNPPPEE-----FLFYLPGQPEGIRSSNTYTLTDVR 304
I + P + EG +TL C L GNP PE L +RS + + V+
Sbjct: 892 IGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQ 951
Query: 305 RNATGDYKCSLIDKKSMI-ASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNAT 363
G+Y C + +T++ VH L + ++ G + + C S + +
Sbjct: 952 LQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPS 1011
Query: 364 VVWMKDNIRLR-SSPSFS-----SLHY-----QDAGNYVCETALQEVEGLKKRESLTLIV 412
V+W K + SS FS SL+ +++G YVC TA K++ LT+ V
Sbjct: 1012 VIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVC-TATNTAGYAKRKVQLTVYV 1070
Query: 413 E--------GKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQW 447
G Q K + + +G T+ C V+ P P I W
Sbjct: 1071 RPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITW 1113
Score = 48.5 bits (114), Expect = 2e-05
Identities = 92/458 (20%), Positives = 163/458 (35%), Gaps = 77/458 (16%)
Query: 88 DRLNLSEN-YTLSISNARISDEKRFVCMLVT----EDNVFEAPTIVKVFKQPSKPEIVSK 142
+R+ +S N TL+I A SD ++ C+ ED +F V + +K E
Sbjct: 3293 ERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKL 3352
Query: 143 ALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMT 202
++T + P I W +NG L PL + ++ ++ + +
Sbjct: 3353 MTLVDTS----INIECRATGTPPPQINWLKNGLPL-PLSSHIRLLAAGQVIRIVRAQV-- 3405
Query: 203 STLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVF-----DIYYPTEQVTIQVLPPK 257
+D+ + +TC + +G H VF D TE++T+
Sbjct: 3406 ---------SDVAV-YTCVAS--NRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL----- 3448
Query: 258 NAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYT-------LTDVRRNATGD 310
+G + ++ C+ +G P P + GQP G+ + T + L +G
Sbjct: 3449 ----KGSSTSMACITDGTPAPS-MAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGK 3503
Query: 311 YKCSLIDKKSMIASTAITVHYLDLSLNPSGE---VTRQIGDALPVSCTISASRNATVVWM 367
Y C ++ ++ I +N S E ++ + + L ++C S + WM
Sbjct: 3504 YTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWM 3563
Query: 368 KDNIRLRSSPS-----------FSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKP 416
KD L + S+ +D G Y C G +E L + V P
Sbjct: 3564 KDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTC--LASSPAGDDDKEYL-VRVHVPP 3620
Query: 417 QIKMTKK----TDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYI----NGR 468
I T + T T+ C + P P I W G + + +P + GR
Sbjct: 3621 NIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNG-----ERLQATPRVRILSGGR 3675
Query: 469 YYSKIIISPEENVTLTCTAENQLERTVNSLNVSAISIP 506
Y + TC A N +T + +++P
Sbjct: 3676 YLQINNADLGDTANYTCVASNIAGKTTREF-ILTVNVP 3712
Score = 46.6 bits (109), Expect = 6e-05
Identities = 90/419 (21%), Positives = 156/419 (37%), Gaps = 94/419 (22%)
Query: 86 YKDRLNLSENYTL-SISNARI--------SDEKRFVCMLVT---------EDNVFEAPTI 127
YKD + ++E+ T+ +++N +I D R+ C + +V PTI
Sbjct: 1395 YKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTI 1454
Query: 128 VKVFKQPSKPEIVSKALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVII 187
+ ++++ + LE + + +PD I W+++GK L
Sbjct: 1455 IGTNFPNEVSVVLNRDVALECQ--------VKGTPFPD--IHWFKDGKPLFL-------- 1496
Query: 188 FKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTE 247
DP +L L K + + + + C+V+ K I IY P
Sbjct: 1497 ----GDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIK-----LTIYIPPS 1547
Query: 248 ----QVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTD- 302
VT + N++ I L+C G P P +Y GQP I SS+ D
Sbjct: 1548 IKGGNVTTDISVLINSL-----IKLECETRGLPMPA-ITWYKDGQP--IMSSSQALYIDK 1599
Query: 303 -----VRRNATGD---YKCSLIDKKSMIASTAITVHYLDLSLNPSGE------VTRQ--I 346
+ R D Y C + + +A TA ++D+ + P E + +Q I
Sbjct: 1600 GQYLHIPRAQVSDSATYTCHVAN----VAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVI 1655
Query: 347 GDALPVSCTISASRNATVVWMKDNIRLRSSPSFS-----------SLHYQDAGNYVCETA 395
+L + C + + + + W+KD + ++++ + S D G Y+C
Sbjct: 1656 AHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVAT 1715
Query: 396 LQEVEGLKKRESLTLI---VEGKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITG 451
E K E L+ +EG + + L + CHV G P P I W G
Sbjct: 1716 SVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLE--LDCHVTGSPPPTIMWLKDG 1772
Score = 45.8 bits (107), Expect = 1e-04
Identities = 66/315 (20%), Positives = 108/315 (34%), Gaps = 54/315 (17%)
Query: 161 DSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTC 220
D P +ITW+++G+ + ++ + Q + +L+ + +TC
Sbjct: 4103 DGLPPPDITWHKDGRAI--------------VESIRQRVLSSGSLQIAFVQPGDAGHYTC 4148
Query: 221 SVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPE- 279
S S ++ P I+ + E L C+ +G P P
Sbjct: 4149 MAANVAGSS-----STSTKLTVHVPPR---IRSTEGHYTVNENSQAILPCVADGIPTPAI 4200
Query: 280 ----------EFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIAST-AIT 328
L +P G L D +G Y C + T ++T
Sbjct: 4201 NWKKDNVLLANLLGKYTAEPYGELILENVVLED-----SGFYTCVANNAAGEDTHTVSLT 4255
Query: 329 VHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDN---------IRLRSSPSF 379
VH L G+V+ G+ L +SC + + W +N + S
Sbjct: 4256 VHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVI 4315
Query: 380 SSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIK---MTKKTDPSGLSKTIICH 436
+ +D+G YVC TA V G K + E P K + +P G + + C
Sbjct: 4316 ERVSKEDSGTYVC-TAENSV-GFVKAIGFVYVKE-PPVFKGDYPSNWIEPLGGNAILNCE 4372
Query: 437 VEGFPKPAIQWTITG 451
V+G P P IQW G
Sbjct: 4373 VKGDPTPTIQWNRKG 4387
Score = 44.7 bits (104), Expect = 2e-04
Identities = 89/420 (21%), Positives = 145/420 (34%), Gaps = 58/420 (13%)
Query: 98 LSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQP--SKPEIVSKALFLETEQLKKLG 155
L + A D ++ C+ E I+KV + P + E + + L+
Sbjct: 3491 LQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELT- 3549
Query: 156 DCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQ 215
CI+ P +TW ++G+ L + D V Q L T + +
Sbjct: 3550 -CIAS-GIPAPKMTWMKDGRPL------------PQTDQV-QTLGGGEVLRISTAQVEDT 3594
Query: 216 MPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGN 275
+TC + P+G ++ + ++ P P + +TL+C +
Sbjct: 3595 GRYTCLAS--SPAGDD---DKEYLVRVHVPPNIAGTDE-PRDITVLRNRQVTLECKSDAV 3648
Query: 276 PPPEEFLFY----LPGQPE-GIRSSNTYT-LTDVRRNATGDYKCSLIDKKSMIASTAITV 329
PPP L P I S Y + + T +Y C S IA
Sbjct: 3649 PPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVA----SNIAGKTTRE 3704
Query: 330 HYLDLSLNPSGEVTRQ-----IGDALPVSCTISASRNATVVWMKDNIRLRSSPS------ 378
L +++ P+ + Q + + + C + W KD L + +
Sbjct: 3705 FILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILE 3764
Query: 379 -----FSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKM--TKKTDPSGLSK 431
S H D G Y+C G +R + L V P I T T +
Sbjct: 3765 NGFLHIQSAHVTDTGRYLCMAT--NAAGTDRRR-IDLQVHVPPSIAPGPTNMTVIVNVQT 3821
Query: 432 TIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISP--EENVTLTCTAEN 489
T+ C G PKP+I W G ++Q + S Y S +IISP ++ T CT N
Sbjct: 3822 TLACEATGIPKPSINWRKNGHLLNVDQNQNS-YRLLSSGSLVIISPSVDDTATYECTVTN 3880
Score = 44.3 bits (103), Expect = 3e-04
Identities = 45/220 (20%), Positives = 89/220 (40%), Gaps = 21/220 (9%)
Query: 250 TIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFY----LPGQPEGIRSSNTYTLTDVRR 305
T LP ++ +G+ + L C G P P+ + +P + + + + V +
Sbjct: 4261 TFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSK 4320
Query: 306 NATGDYKCSLIDKKSMIASTAITVHYLDLSL----NPSGEVTRQIGDALPVSCTISASRN 361
+G Y C+ + + + V+ + + PS + G+A+ ++C +
Sbjct: 4321 EDSGTYVCTAENSVGFVKAIGF-VYVKEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPT 4378
Query: 362 ATVVWMKDNI------RLRSSPSFSSLHY----QDAGNYVCETALQEVEGLKKRESLTLI 411
T+ W + + R+R + S Y +DAG+Y C A E +++ SLTL
Sbjct: 4379 PTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTC-VATNEAGVVERSMSLTLQ 4437
Query: 412 VEGKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITG 451
++ + +G + C G P+P I W+ G
Sbjct: 4438 SPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQG 4477
Score = 42.0 bits (97), Expect = 0.002
Identities = 89/472 (18%), Positives = 169/472 (35%), Gaps = 67/472 (14%)
Query: 92 LSENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQL 151
L++ L I A +SD ++VC + + + V+ PS E + + +ET
Sbjct: 3109 LADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSI-EGPEREVIVETISN 3167
Query: 152 KKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTK 211
C P I W +N K + + V ++ + S L+ ++
Sbjct: 3168 PVTLTC-DATGIPPPTIAWLKNHKRIENSDSLEV-----------RILSGGSKLQIARSQ 3215
Query: 212 ADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQV----LPPKNAIKEGDNIT 267
+TC + QK Y+ + QV V +P ++ G+N+
Sbjct: 3216 HSDSGNYTCIASNMEGKAQK----------YYFLSIQVPPSVAGAEIPSDVSVLLGENVE 3265
Query: 268 LKCLGNGNPPP-----EEFLFYLPGQPEGIRSS---NTYTLTDVRRNATGDYKCSLIDKK 319
L C NG P P ++ G+ E IR S +T + + TG Y C +
Sbjct: 3266 LVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNP- 3324
Query: 320 SMIASTAITVHYLDLSLNPS--------GEVTRQIGDALPVSCTISASRNATVVWMKDNI 371
A + L++ + P+ ++ + ++ + C + + + W+K+ +
Sbjct: 3325 ---AGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGL 3381
Query: 372 RLRSSPSFSSL-----------HYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKM 420
L S L D Y C + + G+ + L V P +
Sbjct: 3382 PLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRA--GVDNKH-YNLQVFAPPNMDN 3438
Query: 421 TKKTDP----SGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIIS 476
+ T+ G S ++ C +G P P++ W G ++ + +G +
Sbjct: 3439 SMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLD-AHLTVSTHGMVLQLLKAE 3497
Query: 477 PEENVTLTCTAENQLERTVNSLNVSAISIPEHDEADEISDENREKVNDQAKL 528
E++ TC A N+ V+ + + P H E +E VN+ +L
Sbjct: 3498 TEDSGKYTCIASNEAGE-VSKHFILKVLEPPHINGSEEHEEISVIVNNPLEL 3548
Score = 41.6 bits (96), Expect = 0.002
Identities = 88/451 (19%), Positives = 161/451 (35%), Gaps = 57/451 (12%)
Query: 87 KDRLNLSENYT-LSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPS--KPEIVSKA 143
K L++SEN + L I +A++ D R+ C E V ++ P+ + +++
Sbjct: 2147 KPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQL 2206
Query: 144 LFLETEQLKKLGDCISEDSYPDGNITWYRNGK-VLHPLEGAVVIIFKKEMDPVTQLYTMT 202
+E + L + P N+ W + G VL G V I+ ++
Sbjct: 2207 TVIEGNLISLLCE---SSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISI----- 2258
Query: 203 STLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKE 262
K+D + ++C + + +K + + +Y P + +
Sbjct: 2259 ------AEKSDAAL-YSCVASNVAGTAKKEYNLQ-----VYIRPTITNSGSHPTEIIVTR 2306
Query: 263 GDNITLKCLGNGNPPPEEFLFYLPGQP-------EGIRSSNTYTLTDVRRNATGDYKCSL 315
G +I+L+C G PPP + G P E + + L ++ + TG Y C
Sbjct: 2307 GKSISLECEVQGIPPPT-VTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVA 2365
Query: 316 IDKKSMIASTAITVHYLDLSLNPSGEVTRQIG----DALPVSCTISASRNATVVWMKDNI 371
++ M + S+ + I +++ ++C S ++ W KD
Sbjct: 2366 VNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGW 2425
Query: 372 RLRSSPSFSSLH-----------YQDAGNYVCETALQEVEGLKKRESLTLI---VEGKPQ 417
+ S S L +DAG Y C E K L+ + G+
Sbjct: 2426 PVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENT 2485
Query: 418 IKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYI--NGRYYSKIII 475
++ K + S T+ C V G P P I W G Q +E+ +I GR+ +
Sbjct: 2486 LEDVKVKEKQ--SVTLTCEVTGNPVPEITWHKDGQPL---QEDEAHHIISGGRFLQITNV 2540
Query: 476 SPEENVTLTCTAENQLERTVNSLNVSAISIP 506
TC A + S +++ P
Sbjct: 2541 QVPHTGRYTCLASSPAGHKSRSFSLNVFVSP 2571
Score = 37.7 bits (86), Expect = 0.029
Identities = 56/285 (19%), Positives = 97/285 (34%), Gaps = 34/285 (11%)
Query: 251 IQVLPPKNAIKEGDNITLKCLGNGNPPPE------EFLFYLPGQPEGIRSSNTYTLTDVR 304
IQ P ++ G + + C G P P + G+ T ++
Sbjct: 1173 IQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQAT 1232
Query: 305 RNATGDYKCSLIDKKSMIASTAITVHYLDL----SLNPSGEVT---RQIGDALPVSCTIS 357
+ G Y C + + T IT+H + L P T R + C
Sbjct: 1233 PSDAGIYTC-VATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAK 1291
Query: 358 ASRNATVVWMKDNIRLRS-SPSFS-----------SLHYQDAGNYVCETALQEVEGLKKR 405
+ T+ W+ + L P S S+ D G Y+C A+ E +++
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYIC-VAVNEAGTTERK 1350
Query: 406 ESLTL----IVEGKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEE 461
+L + +++ K Q+ T + + C VEG P P I W + V +
Sbjct: 1351 YNLKVHVPPVIKDKEQV--TNVSVLLNQLTNLFCEVEGTPSPIIMW-YKDNVQVTESSTI 1407
Query: 462 SPYINGRYYSKIIISPEENVTLTCTAENQLERTVNSLNVSAISIP 506
NG+ +PE+ +C A N + N+ + P
Sbjct: 1408 QTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPP 1452
Score = 36.6 bits (83), Expect = 0.065
Identities = 77/385 (20%), Positives = 140/385 (36%), Gaps = 61/385 (15%)
Query: 98 LSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGDC 157
L I +A+ D +++C+ + E V V P+ + F+ DC
Sbjct: 1697 LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDC 1756
Query: 158 ISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYK----TTKAD 213
S P I W ++G+++ +G +++ +++ V +++T Y+ T D
Sbjct: 1757 HVTGS-PPPTIMWLKDGQLIDERDGFKILLNGRKL--VIAQAQVSNTGLYRCMAANTAGD 1813
Query: 214 IQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGN 273
+ F VT + P TI S +E+V ++ P + L+C+ N
Sbjct: 1814 HKKEF--EVTVHVPP---TIKSSGL-------SERVVVKYKP----------VALQCIAN 1851
Query: 274 GNPPPEEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAI--TVHY 331
G P P + QP N + R + + +A+ A T +
Sbjct: 1852 GIPNPS-ITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQH 1910
Query: 332 LDL------SLNPSGEVTRQ---IGDALPVSCTISASRNATVVWMKDNIRLRSSPSFS-- 380
+ L SL +G++ + + + + + C + + + W KDN L S S +
Sbjct: 1911 IQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFL 1970
Query: 381 ---------SLHYQDAGNYVCETALQEVEGLKKRESLTL----IVEGKPQIKMTKKTDPS 427
S DAG Y C A+ + SL + + G + +P
Sbjct: 1971 NRGQIIDIESAQISDAGIYKC-VAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 428 GLSKTIICHVEGFPKPAIQWTITGS 452
L C G P P++ W GS
Sbjct: 2030 RLE----CEARGIPAPSLTWLKDGS 2050
>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
Length = 398
Score = 76.3 bits (186), Expect = 7e-14
Identities = 74/327 (22%), Positives = 136/327 (41%), Gaps = 45/327 (13%)
Query: 5 GASSCRLLFCLLISATVFRPGLG---------WYTVNSAY-GDTIIIPCRLDVPQNLMFG 54
GA + LL LL+ A + PG W + + G T+++ C++
Sbjct: 2 GAPAASLLLLLLLFACCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVK-------- 53
Query: 55 KWKYEKPDGSPVFIAFRSSTKKSVQYDDVPEYKD-RLNL----SENYTLSISNARISDEK 109
D + + + ++++ + + +D R+ L ++SISN ++DE
Sbjct: 54 -------DHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEG 106
Query: 110 RFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGDCISEDSYPDGNIT 169
+ C + T V A ++V V P KP I L + L +C S S P +T
Sbjct: 107 EYTCSIFTMP-VRTAKSLVTVLGIPQKPIITGYKSSLREKDTATL-NCQSSGSKPAARLT 164
Query: 170 WYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSG 229
W + + LH + + DP + +T++S++ ++ T+ D CSV + G
Sbjct: 165 WRKGDQELHGEPTRI------QEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKG 218
Query: 230 QKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQ- 288
S Q + +Y PT + P +EG + L C G GNP P+++L+ G
Sbjct: 219 ADRSTS-QRIEVLYTPTAMIR----PDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSV 273
Query: 289 -PEGIRSSNTYTLTDVRRNATGDYKCS 314
P + + + ++ +G Y C+
Sbjct: 274 PPLKMTQESALIFPFLNKSDSGTYGCT 300
>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
Length = 432
Score = 75.5 bits (184), Expect = 1e-13
Identities = 57/220 (25%), Positives = 98/220 (44%), Gaps = 15/220 (6%)
Query: 97 TLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGD 156
++SISN ++DE + C + T V A ++V V P KP I L + L +
Sbjct: 128 SISISNVALADEGEYTCSIFTMP-VRTAKSLVTVLGIPQKPIITGYKSSLREKDTATL-N 185
Query: 157 CISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQM 216
C S S P +TW + + LH + + DP + +T++S++ ++ T+ D
Sbjct: 186 CQSSGSKPAARLTWRKGDQELHGEPTRI------QEDPNGKTFTVSSSVTFQVTREDDGA 239
Query: 217 PFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNP 276
CSV + G S Q + +Y PT + P +EG + L C G GNP
Sbjct: 240 SIVCSVNHESLKGADRSTS-QRIEVLYTPTAMIR----PDPPHPREGQKLLLHCEGRGNP 294
Query: 277 PPEEFLFYLPGQ--PEGIRSSNTYTLTDVRRNATGDYKCS 314
P+++L+ G P + + + ++ +G Y C+
Sbjct: 295 VPQQYLWEKEGSVPPLKMTQESALIFPFLNKSDSGTYGCT 334
>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
Length = 437
Score = 74.7 bits (182), Expect = 2e-13
Identities = 78/347 (22%), Positives = 148/347 (42%), Gaps = 41/347 (11%)
Query: 36 GDTIIIPCRLDVPQNLMFGKWKYEKPDGSPVFIAFRSSTKKSVQYDDVPEYKD-RLNLSE 94
G T I+ CR+D N +W + ++++ +DD +D R+ L
Sbjct: 39 GGTAILTCRVDQNDNTSL-QWS--------------NPAQQTLYFDDKKALRDNRIELVR 83
Query: 95 ----NYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQ 150
++S+S+ +SDE ++ C L T V + + V P KP+I + +
Sbjct: 84 ASWHELSISVSDVSLSDEGQYTCSLFTMP-VKTSKAYLTVLGVPEKPQISGFSSPVMEGD 142
Query: 151 LKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTT 210
L +L C + S P +I W++N K + ++ + KE D + +T++STL+++
Sbjct: 143 LMQL-TCKTSGSKPAADIRWFKNDKEIKDVK------YLKEEDANRKTFTVSSTLDFRVD 195
Query: 211 KADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKC 270
++D + C V + S T V +I+Y +++++P +EG + L C
Sbjct: 196 RSDDGVAVICRVDH--ESLNATPQVAMQVLEIHYTP---SVKIIPSTPFPQEGQPLILTC 250
Query: 271 LGNGNPPPEEFLF-----YLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDK-KSMIAS 324
G P PE L+ LP + S + + + G Y+C + A
Sbjct: 251 ESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAE 310
Query: 325 TAITVHYLDLSLNPSGEVTRQIGDAL--PVSCTISASRNATVVWMKD 369
+ VH + +L P+ + + V+ T S + +AT ++D
Sbjct: 311 YVLIVHDVPNTLLPTTIIPSLTTATVTTTVAITTSPTTSATTSSIRD 357
>gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens]
Length = 600
Score = 71.6 bits (174), Expect = 2e-12
Identities = 112/479 (23%), Positives = 186/479 (38%), Gaps = 60/479 (12%)
Query: 91 NLSENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQ 150
+LS + L I A + D+ + C + + + P + V P P I+ +
Sbjct: 105 HLSGEHHLKILRAELQDDAVYECQAI-QAAIRSRPARLTVLVPPDDPVILGGPVIS---- 159
Query: 151 LKKLGD-----CISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTL 205
+ GD C ++++ P +I W R G+V++ GA + K + + ++ STL
Sbjct: 160 -LRAGDPLNLTCHADNAKPAASIIWLRKGEVIN---GAT---YSKTLLRDGKRESIVSTL 212
Query: 206 EYKTTKADIQMPFTCSVTYYG-PSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGD 264
+ C T P G++T DI +P V + V P + E +
Sbjct: 213 FISPGDVENGQSIVCRATNKAIPGGKET----SVTIDIQHPP-LVNLSVEP--QPVLEDN 265
Query: 265 NITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKK-SMIA 323
+T C NP ++ + GQ S Y T + C + + S
Sbjct: 266 VVTFHCSAKANPAVTQYRWAKRGQIIKEASGEVYRTTVDYTYFSEPVSCEVTNALGSTNL 325
Query: 324 STAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDN----IRLRSSPSF 379
S + V++ + +G SC + + + T+VWMK + + +
Sbjct: 326 SRTVDVYFGPRMTTEPQSLLVDLGSDAIFSCAWTGNPSLTIVWMKRGSGVVLSNEKTLTL 385
Query: 380 SSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDP-SGLSKTIICHVE 438
S+ +DAG YVC + V G +RE +TL V G P I T+ G I C +
Sbjct: 386 KSVRQEDAGKYVCRAVVPRV-GAGERE-VTLTVNGPPIISSTQTQHALHGEKGQIKCFIR 443
Query: 439 GFPKP-AIQWT----ITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCTAENQLE- 492
P P I W+ + SG+ +GRY + IS EE V T T N +
Sbjct: 444 STPPPDRIAWSWKENVLESGT-----------SGRYTVE-TISTEEGVISTLTISNIVRA 491
Query: 493 --RTV------NSLNVSAISIPEHDEADEI-SDENREKVNDQAKLIVGIVVGLLLAALV 542
+T+ NS I ++ E+ S E + +I+G+ VG +A LV
Sbjct: 492 DFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFLV 550
>gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens]
Length = 778
Score = 71.6 bits (174), Expect = 2e-12
Identities = 112/479 (23%), Positives = 186/479 (38%), Gaps = 60/479 (12%)
Query: 91 NLSENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQ 150
+LS + L I A + D+ + C + + + P + V P P I+ +
Sbjct: 105 HLSGEHHLKILRAELQDDAVYECQAI-QAAIRSRPARLTVLVPPDDPVILGGPVIS---- 159
Query: 151 LKKLGD-----CISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTL 205
+ GD C ++++ P +I W R G+V++ GA + K + + ++ STL
Sbjct: 160 -LRAGDPLNLTCHADNAKPAASIIWLRKGEVIN---GAT---YSKTLLRDGKRESIVSTL 212
Query: 206 EYKTTKADIQMPFTCSVTYYG-PSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGD 264
+ C T P G++T DI +P V + V P + E +
Sbjct: 213 FISPGDVENGQSIVCRATNKAIPGGKET----SVTIDIQHPP-LVNLSVEP--QPVLEDN 265
Query: 265 NITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKK-SMIA 323
+T C NP ++ + GQ S Y T + C + + S
Sbjct: 266 VVTFHCSAKANPAVTQYRWAKRGQIIKEASGEVYRTTVDYTYFSEPVSCEVTNALGSTNL 325
Query: 324 STAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDN----IRLRSSPSF 379
S + V++ + +G SC + + + T+VWMK + + +
Sbjct: 326 SRTVDVYFGPRMTTEPQSLLVDLGSDAIFSCAWTGNPSLTIVWMKRGSGVVLSNEKTLTL 385
Query: 380 SSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDP-SGLSKTIICHVE 438
S+ +DAG YVC + V G +RE +TL V G P I T+ G I C +
Sbjct: 386 KSVRQEDAGKYVCRAVVPRV-GAGERE-VTLTVNGPPIISSTQTQHALHGEKGQIKCFIR 443
Query: 439 GFPKP-AIQWT----ITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCTAENQLE- 492
P P I W+ + SG+ +GRY + IS EE V T T N +
Sbjct: 444 STPPPDRIAWSWKENVLESGT-----------SGRYTVE-TISTEEGVISTLTISNIVRA 491
Query: 493 --RTV------NSLNVSAISIPEHDEADEI-SDENREKVNDQAKLIVGIVVGLLLAALV 542
+T+ NS I ++ E+ S E + +I+G+ VG +A LV
Sbjct: 492 DFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFLV 550
>gi|21686977 cell adhesion molecule 4 [Homo sapiens]
Length = 388
Score = 68.9 bits (167), Expect = 1e-11
Identities = 81/334 (24%), Positives = 134/334 (40%), Gaps = 53/334 (15%)
Query: 15 LLISATVFRPGLGWYT----VNSAYGDTIIIPCRLDVPQNLMFGKWKYEKPDGSPVFIAF 70
LL+ A PG G V A G I CRL + DGS V I
Sbjct: 12 LLLWAAAAGPGAGQEVQTENVTVAEGGVAEITCRL-------------HQYDGSIVVI-- 56
Query: 71 RSSTKKSVQYDDVPEYKD-RLNLSE----NYTLSISNARISDEKRFVCMLVTEDNVFEAP 125
++ ++++ ++ KD R L E + +S+AR+ DE + C L TED +
Sbjct: 57 QNPARQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIA 116
Query: 126 TIVKVFKQPSKPEIVSKALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVV 185
T+ V P P + + +E +++ C+ S P + WYR+ K L + +
Sbjct: 117 TLT-VLVAPENPVVEVREQAVEGGEVEL--SCLVPRSRPAATLRWYRDRKELKGVSSS-- 171
Query: 186 IIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYG-PSGQKTIHSEQA--VFDI 242
+++++ ST+ ++ + D C PSG HS+Q V D+
Sbjct: 172 -------QENGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPSG----HSKQTQYVLDV 220
Query: 243 YYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLF-----YLPGQPEGIRSSNT 297
Y T ++ + ++EGD + L C GNP P + + LP + E + T
Sbjct: 221 QYSP---TARIHASQAVVREGDTLVLTCAVTGNPRPNQIRWNRGNESLPERAEAV--GET 275
Query: 298 YTLTDVRRNATGDYKCSLIDKKSMIASTAITVHY 331
TL + G Y C +K + + V Y
Sbjct: 276 LTLPGLVSADNGTYTCEASNKHGHARALYVLVVY 309
>gi|166295173 kin of IRRE like [Homo sapiens]
Length = 757
Score = 67.4 bits (163), Expect = 3e-11
Identities = 86/333 (25%), Positives = 132/333 (39%), Gaps = 30/333 (9%)
Query: 96 YTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLG 155
Y L I++A +SD+ + C TE + + V P I + L
Sbjct: 83 YNLEITDAELSDDASYECQ-ATEAALRSRRAKLTVLIPPEDTRIDGGPVILLQAGTPHNL 141
Query: 156 DCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQ 215
C + ++ P I W+R+G EGAV E+ + T S L T DI
Sbjct: 142 TCRAFNAKPAATIIWFRDGT---QQEGAVA---STELLKDGKRETTVSQLLINPTDLDIG 195
Query: 216 MPFTC-SVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNG 274
FTC S+ PSG++T D+++P VT+ + P ++EG+ + C
Sbjct: 196 RVFTCRSMNEAIPSGKET----SIELDVHHPPT-VTLSIEP--QTVQEGERVVFTCQATA 248
Query: 275 NPPPEEFLFYLPGQP----EGIRSSNTYTLTDVRRNATGDYKCSLIDKK-SMIASTAITV 329
NP E L Y + E S T D T C + +K S ST + V
Sbjct: 249 NP---EILGYRWAKGGFLIEDAHESRYETNVDYSF-FTEPVSCEVHNKVGSTNVSTLVNV 304
Query: 330 HYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSSPS----FSSLHYQ 385
H+ + T IG + ++C + T+ W K + + S S S+
Sbjct: 305 HFAPRIVVDPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMVLSNSNQLLLKSVTQA 364
Query: 386 DAGNYVCETALQEVEGLKKRESLTLIVEGKPQI 418
DAG Y C + + G+ +RE + L V G P I
Sbjct: 365 DAGTYTCRAIVPRI-GVAERE-VPLYVNGPPII 395
>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
5 preproprotein [Homo sapiens]
Length = 702
Score = 66.6 bits (161), Expect = 6e-11
Identities = 115/522 (22%), Positives = 203/522 (38%), Gaps = 77/522 (14%)
Query: 32 NSAYGDTIIIPCRLDVPQNLMFGKW-KYEKPDGSPVFIAFRSSTKKSVQYDDVPEYKDRL 90
N A G +++ ++PQ+L W K E+ DG+ I + T+++ P Y R
Sbjct: 44 NVAEGKEVLLLVH-NLPQHLFGYSWYKGERVDGNRQIIGYVIGTQQATPG---PAYSGRE 99
Query: 91 NLSENYTLSISNARISDEKRFVCMLVTEDNVFEAPT-IVKVFKQPSKPEIVSKALFLETE 149
+ N +L I N +D + ++ D V E T +V+ + KP I S +
Sbjct: 100 IIYPNASLLIQNIIQNDTGFYTLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVED 159
Query: 150 QLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLE-YK 208
+ C E D W+ N + L + P QL TL +
Sbjct: 160 KDAVAFTC--EPETQDATYLWWVNNQSL-------------PVSPRLQLSNGNRTLTLFN 204
Query: 209 TTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITL 268
T+ D T S + S+ + ++ Y + TI P + + G+N+ L
Sbjct: 205 VTRND-----TASYKCETQNPVSARRSDSVILNVLYGPDAPTIS--PLNTSYRSGENLNL 257
Query: 269 KCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAIT 328
C N PP ++ +++ G + +S+ + ++ N +G Y C + + + T +T
Sbjct: 258 SCHAASN-PPAQYSWFVNGTFQ--QSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTVT 314
Query: 329 --VHYLD-----LSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSSP---- 377
Y + ++ N S V + DA+ ++C +N T +W +N L SP
Sbjct: 315 TITVYAEPPKPFITSNNSNPVEDE--DAVALTCE-PEIQNTTYLWWVNNQSLPVSPRLQL 371
Query: 378 -------SFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIV---EGKPQIKMTKKTDPS 427
+ S+ D G Y C +Q + + + L V P I +
Sbjct: 372 SNDNRTLTLLSVTRNDVGPYEC--GIQNKLSVDHSDPVILNVLYGPDDPTISPSYTYYRP 429
Query: 428 GLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCTA 487
G++ ++ CH P W I G+ I Q + +I+ I+ + + TC A
Sbjct: 430 GVNLSLSCHAASNPPAQYSWLIDGN---IQQHTQELFISN-------ITEKNSGLYTCQA 479
Query: 488 ENQL----ERTVNSLNVSAISIPEHDEADEISDENREKVNDQ 525
N TV ++ VSA +P+ IS N + V D+
Sbjct: 480 NNSASGHSRTTVKTITVSA-ELPK----PSISSNNSKPVEDK 516
Score = 62.4 bits (150), Expect = 1e-09
Identities = 94/463 (20%), Positives = 170/463 (36%), Gaps = 71/463 (15%)
Query: 98 LSISNARISDEKRFVCMLVTEDNVFEAPTI--VKVFKQPSKPEIVSK-ALFLETEQLKKL 154
L I N +++ + C D T+ + V+ +P KP I S + +E E L
Sbjct: 284 LFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVAL 343
Query: 155 GDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADI 214
E + W+ N + L + P QL TL + +
Sbjct: 344 ---TCEPEIQNTTYLWWVNNQSL-------------PVSPRLQLSNDNRTLTLLSVTRND 387
Query: 215 QMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNG 274
P+ C + + HS+ + ++ Y + TI P + G N++L C
Sbjct: 388 VGPYECGIQ----NKLSVDHSDPVILNVLYGPDDPTIS--PSYTYYRPGVNLSLSCHAAS 441
Query: 275 NPPPEEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKS-----MIASTAITV 329
NPP + + + + G + + + ++++ +G Y C + S + + ++
Sbjct: 442 NPPAQ-YSWLIDGNIQ--QHTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSA 498
Query: 330 HYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSSPSFS--------- 380
S++ + + DA+ +C A +N T +W + L SP
Sbjct: 499 ELPKPSISSNNSKPVEDKDAVAFTCEPEA-QNTTYLWWVNGQSLPVSPRLQLSNGNRTLT 557
Query: 381 --SLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDPS---GLSKTIIC 435
++ DA YVC +Q + + +TL V P + D S G + + C
Sbjct: 558 LFNVTRNDARAYVC--GIQNSVSANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSC 615
Query: 436 HVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCTAENQLERTV 495
H P P W I G + Q + +I I+P N T C N
Sbjct: 616 HSASNPSPQYSWRING---IPQQHTQVLFI-------AKITPNNNGTYACFVSNLATGRN 665
Query: 496 NSLNVSAISIPEHDEADEISDENREKVNDQAKLIVGIVVGLLL 538
NS+ V +I++ + +S A VGI++G+L+
Sbjct: 666 NSI-VKSITVSASGTSPGLS----------AGATVGIMIGVLV 697
>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
sapiens]
Length = 414
Score = 65.9 bits (159), Expect = 1e-10
Identities = 80/317 (25%), Positives = 128/317 (40%), Gaps = 46/317 (14%)
Query: 12 LFCLLISATVFRP---GLGWYT--VNSAYGDTIIIPCRLDVPQNLMFGKWKYEKPDGSPV 66
L LL SA P G +T V G+ I C+++ K D S
Sbjct: 28 LLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVN-------------KSDDS-- 72
Query: 67 FIAFRSSTKKSVQYDDVPEYKDR----LNLSEN-YTLSISNARISDEKRFVCMLVTEDNV 121
I + ++++ + D KD LN S + +S++N ISDE R+ C L T D
Sbjct: 73 VIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYT-DPP 131
Query: 122 FEAPTIVKVFKQPSKPEI-VSKALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPL 180
E+ T + V P I + K +E E+++ +C + S P I W++ L
Sbjct: 132 QESYTTITVLVPPRNLMIDIQKDTAVEGEEIEV--NCTAMASKPATTIRWFKGNTELKG- 188
Query: 181 EGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVF 240
K E++ + +YT+TS L K K D +P C V + +G Q
Sbjct: 189 --------KSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNL---QTQRYL 237
Query: 241 DIYYPTEQVTIQVLPPKNAI-KEGDNITLKCLGNGNPPPEEFLFYLPGQ---PEGIRSSN 296
++ Y QV IQ+ P + +EGD + L C G P P + + S
Sbjct: 238 EVQY-KPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGP 296
Query: 297 TYTLTDVRRNATGDYKC 313
+ ++ + G Y+C
Sbjct: 297 NLFINNLNKTDNGTYRC 313
>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
sapiens]
Length = 442
Score = 65.9 bits (159), Expect = 1e-10
Identities = 80/317 (25%), Positives = 128/317 (40%), Gaps = 46/317 (14%)
Query: 12 LFCLLISATVFRP---GLGWYT--VNSAYGDTIIIPCRLDVPQNLMFGKWKYEKPDGSPV 66
L LL SA P G +T V G+ I C+++ K D S
Sbjct: 28 LLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVN-------------KSDDS-- 72
Query: 67 FIAFRSSTKKSVQYDDVPEYKDR----LNLSEN-YTLSISNARISDEKRFVCMLVTEDNV 121
I + ++++ + D KD LN S + +S++N ISDE R+ C L T D
Sbjct: 73 VIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYT-DPP 131
Query: 122 FEAPTIVKVFKQPSKPEI-VSKALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPL 180
E+ T + V P I + K +E E+++ +C + S P I W++ L
Sbjct: 132 QESYTTITVLVPPRNLMIDIQKDTAVEGEEIEV--NCTAMASKPATTIRWFKGNTELKG- 188
Query: 181 EGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVF 240
K E++ + +YT+TS L K K D +P C V + +G Q
Sbjct: 189 --------KSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNL---QTQRYL 237
Query: 241 DIYYPTEQVTIQVLPPKNAI-KEGDNITLKCLGNGNPPPEEFLFYLPGQ---PEGIRSSN 296
++ Y QV IQ+ P + +EGD + L C G P P + + S
Sbjct: 238 EVQY-KPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGP 296
Query: 297 TYTLTDVRRNATGDYKC 313
+ ++ + G Y+C
Sbjct: 297 NLFINNLNKTDNGTYRC 313
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 65.9 bits (159), Expect = 1e-10
Identities = 73/349 (20%), Positives = 134/349 (38%), Gaps = 50/349 (14%)
Query: 65 PVFIAFRSSTKKSVQYDDVPEYKDRLNLSENYTLSISNARISDEKRFVCMLV-TEDNVFE 123
P I R++ + S++ D RLNL ++ TL I N + +D+ + CM V
Sbjct: 275 PEIIWLRNNNELSMKTDS------RLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKT 328
Query: 124 APTIVKVFKQPSKPEIVSKALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGA 183
++ F P++P V + E + + S +P I+W R + P++
Sbjct: 329 QEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPR 388
Query: 184 VVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIY 243
V I T + L + + CS T + ++H+ F I
Sbjct: 389 VNI-------------TPSGGLYIQNVVQGDSGEYACSAT----NNIDSVHA--TAFIIV 429
Query: 244 YPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPG-------QPEGIRSSN 296
Q T V P + EG + +C GNPPP + + G + + SS
Sbjct: 430 QALPQFT--VTPQDRVVIEGQTVDFQCEAKGNPPP--VIAWTKGGSQLSVDRRHLVLSSG 485
Query: 297 TYTLTDVRRNATGDYKC---SLIDKKSMIASTAITVHYLDLSLNPSGEVTRQIGDALPVS 353
T ++ V + G Y+C ++I + ++A + + + + T ++G + +
Sbjct: 486 TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLP 545
Query: 354 CTISASRNATVVWMKDNIRLRSSPSF----------SSLHYQDAGNYVC 392
C+ + W KD +++ S F + + DAG Y C
Sbjct: 546 CSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPADAGRYEC 594
Score = 53.9 bits (128), Expect = 4e-07
Identities = 67/290 (23%), Positives = 113/290 (38%), Gaps = 49/290 (16%)
Query: 250 TIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFY-----LPGQPE-GIRSSNTYTLTDV 303
T + P + G+++TL+C G+PPP LP P I S + +V
Sbjct: 343 TFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNV 402
Query: 304 RRNATGDYKCSLIDKKSMIASTA-ITVHYL-DLSLNPSGEVTRQIGDALPVSCTISASRN 361
+ +G+Y CS + + +TA I V L ++ P V + G + C +
Sbjct: 403 VQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIE-GQTVDFQCEAKGNPP 461
Query: 362 ATVVWMKDNIRL----------RSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLI 411
+ W K +L + S + D G Y C+ A+ + K LT+
Sbjct: 462 PVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQ-AVNIIGSQKVVAHLTV- 519
Query: 412 VEGKPQIKMTKKTDPS------GLSKTIICHVEGFPKPAIQWT-----ITGSGSVINQTE 460
+P++ + PS G + + C +G P+PAI W +T SG E
Sbjct: 520 ---QPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPE 576
Query: 461 ESPYINGRYYSKIIISPEENVTLTCTAENQLERTVNSLNVS---AISIPE 507
IN + P + C A N T+ S +VS ++++P+
Sbjct: 577 GFLTIND-------VGPADAGRYECVARN----TIGSASVSMVLSVNVPD 615
Score = 49.7 bits (117), Expect = 7e-06
Identities = 48/234 (20%), Positives = 91/234 (38%), Gaps = 34/234 (14%)
Query: 247 EQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPE---------GIRSSNT 297
E+ I P + G+ + C GNP PE + +L E + T
Sbjct: 244 ERPRITSEPQDADVTSGNTVYFTCRAEGNPKPE--IIWLRNNNELSMKTDSRLNLLDDGT 301
Query: 298 YTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTRQ-----IGDALPV 352
+ + + G Y+C + + + +T+ Y P+ + Q +G+++ +
Sbjct: 302 LMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTL 361
Query: 353 SCTISASRNATVVWMKD-------NIRLRSSPSFSSLHYQ-----DAGNYVCETALQEVE 400
C+ + + W + + R+ +PS L+ Q D+G Y C +A ++
Sbjct: 362 ECSATGHPPPRISWTRGDRTPLPVDPRVNITPS-GGLYIQNVVQGDSGEYAC-SATNNID 419
Query: 401 GLKKRESLTLIVEGKPQIKMT--KKTDPSGLSKTIICHVEGFPKPAIQWTITGS 452
+ + +IV+ PQ +T + G + C +G P P I WT GS
Sbjct: 420 SV--HATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGS 471
>gi|4507875 vascular cell adhesion molecule 1 isoform a precursor
[Homo sapiens]
Length = 739
Score = 60.1 bits (144), Expect = 6e-09
Identities = 71/359 (19%), Positives = 141/359 (39%), Gaps = 28/359 (7%)
Query: 97 TLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGD 156
TL+++ +E ++C E E V+++ P PEI + +
Sbjct: 79 TLTMNPVSFGNEHSYLCTATCESRKLEKGIQVEIYSFPKDPEIHLSGPLEAGKPITV--K 136
Query: 157 CISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKA--DI 214
C D YP + + L+G ++ ++ ++ + T +LE T DI
Sbjct: 137 CSVADVYPFDRLE-------IDLLKGDHLMKSQEFLEDADRKSLETKSLEVTFTPVIEDI 189
Query: 215 QMPFTCSVTYYGPSGQKTIHSEQAVFDIY-YPTEQVTIQVLPPKNAIKEGDNITLKCLGN 273
C + QAV ++ Y + + T+ + P ++EG ++T+ C
Sbjct: 190 GKVLVCRAKLHIDEMDSVPTVRQAVKELQVYISPKNTVISVNPSTKLQEGGSVTMTCSSE 249
Query: 274 GNPPPEEFLFYL--PGQPEGIRSSNTYTLTDVRRNATGDYKC---SLIDKKSMIASTAIT 328
G P PE F G + + + T TL +R +G Y C +LI K +
Sbjct: 250 GLPAPEIFWSKKLDNGNLQHLSGNATLTLIAMRMEDSGIYVCEGVNLIGKNRKEVELIVQ 309
Query: 329 VHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVW-------MKDNIR---LRSSPS 378
+ ++P + QIGD++ ++C++ + + W + +R S+ +
Sbjct: 310 EKPFTVEISPGPRIAAQIGDSVMLTCSVMGCESPSFSWRTQIDSPLSGKVRSEGTNSTLT 369
Query: 379 FSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDPSGLSKTIICHV 437
S + +++ +Y+C + K + P+I+M+ +G S T+ C V
Sbjct: 370 LSPVSFENEHSYLCTVTCGHKKLEKGIQVELYSFPRDPEIEMSGGL-VNGSSVTVSCKV 427
Score = 51.2 bits (121), Expect = 3e-06
Identities = 72/343 (20%), Positives = 134/343 (39%), Gaps = 33/343 (9%)
Query: 95 NYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKL 154
N TL++S +E ++C + E V+++ P PEI + +
Sbjct: 365 NSTLTLSPVSFENEHSYLCTVTCGHKKLEKGIQVELYSFPRDPEIEMSGGLVNGSSVTV- 423
Query: 155 GDCISEDSYPDGNITWYRNGKVLHPLEGAVV---IIFKKEMDPVTQLYTMTSTLEYKTTK 211
C YP + + L+G + I F ++ D + L + + + T
Sbjct: 424 -SCKVPSVYPLDRLE-------IELLKGETILENIEFLEDTD-MKSLENKSLEMTFIPTI 474
Query: 212 ADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYY-PTEQVTIQVLPPKNAIKEGDNITLKC 270
D C + + Q+ +Y + T ++ P + ++EG ++ + C
Sbjct: 475 EDTGKALVCQAKLHIDDMEFEPKQRQSTQTLYVNVAPRDTTVLVSPSSILEEGSSVNMTC 534
Query: 271 LGNGNPPPE-EFLFYLP-GQPEGIRSSNTYTLTDVRRNATGDYKCSLID-----KKSMIA 323
L G P P+ + LP G+ + + + T TL + +G Y C I+ +K +
Sbjct: 535 LSQGFPAPKILWSRQLPNGELQPLSENATLTLISTKMEDSGVYLCEGINQAGRSRKEVEL 594
Query: 324 STAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMK-----DNI--RLRSS 376
+T + L+ PS V GD + +SCT ++ K D + + +
Sbjct: 595 IIQVTPKDIKLTAFPSESVKE--GDTVIISCTCGNVPETWIILKKKAETGDTVLKSIDGA 652
Query: 377 PSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIK 419
+ +DAG Y CE+ + L+ SLTL V+G+ K
Sbjct: 653 YTIRKAQLKDAGVYECESKNKVGSQLR---SLTLDVQGRENNK 692
Score = 36.2 bits (82), Expect = 0.086
Identities = 65/310 (20%), Positives = 112/310 (36%), Gaps = 50/310 (16%)
Query: 225 YGPSGQKTIHSEQAVFDIYYPTEQVTIQVLP-PKNAIKEGDNITLKCLGNGNPPPE---- 279
Y G I + ++ + T+++ P P+ A + GD++ L C G P
Sbjct: 289 YVCEGVNLIGKNRKEVELIVQEKPFTVEISPGPRIAAQIGDSVMLTCSVMGCESPSFSWR 348
Query: 280 -EFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNP 338
+ L G+ +++T TL+ V Y C++ + I V +P
Sbjct: 349 TQIDSPLSGKVRSEGTNSTLTLSPVSFENEHSYLCTVTCGHKKLEK-GIQVELYSFPRDP 407
Query: 339 SGEVTRQI--GDALPVSCTISAS-----------RNATVVWMKDNIRLRSSPSFSSLH-- 383
E++ + G ++ VSC + + + T++ +NI SL
Sbjct: 408 EIEMSGGLVNGSSVTVSCKVPSVYPLDRLEIELLKGETIL---ENIEFLEDTDMKSLENK 464
Query: 384 ---------YQDAGN-YVCETALQ----EVEGLKKRESLTLIVEGKPQIKMTKKTDPS-- 427
+D G VC+ L E E +++ + TL V P+ T PS
Sbjct: 465 SLEMTFIPTIEDTGKALVCQAKLHIDDMEFEPKQRQSTQTLYVNVAPR-DTTVLVSPSSI 523
Query: 428 ---GLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTLT 484
G S + C +GFP P I W+ + E P + I E++
Sbjct: 524 LEEGSSVNMTCLSQGFPAPKILWS-----RQLPNGELQPLSENATLTLISTKMEDSGVYL 578
Query: 485 CTAENQLERT 494
C NQ R+
Sbjct: 579 CEGINQAGRS 588
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 60.1 bits (144), Expect = 6e-09
Identities = 65/308 (21%), Positives = 116/308 (37%), Gaps = 46/308 (14%)
Query: 164 PDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVT 223
P+ NITW ++G+ + EG I + L K + +TC+
Sbjct: 2874 PEPNITWDKDGQPVSGAEGKFTI-------------QPSGELLVKNLEGQDAGTYTCTAE 2920
Query: 224 YYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLF 283
++ +H V ++ LP +++ GD + L+C G+P P +
Sbjct: 2921 NAVGRARRRVHLTILVLPVF--------TTLPGDRSLRLGDRLWLRCAARGSPTP-RIGW 2971
Query: 284 YLPGQP--EGIR---SSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLD---LS 335
+ +P EG+ +T V R +G Y C ++ + + VH + L
Sbjct: 2972 TVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSF-VHVKEAPVLQ 3030
Query: 336 LNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSSP----------SFSSLHYQ 385
+ +G ++ + C + + W+KD + LR S +
Sbjct: 3031 GEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERD 3090
Query: 386 DAGNYVCETALQEVEGLKKRESLTLIVEGKP--QIKMTKKTDPSGLSKTIICHVEGFPKP 443
DAG Y C L E E ++ + L+++ P Q++ T SG + C G P P
Sbjct: 3091 DAGRYQC---LAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTP 3147
Query: 444 AIQWTITG 451
I+W G
Sbjct: 3148 TIEWLQAG 3155
Score = 54.3 bits (129), Expect = 3e-07
Identities = 60/274 (21%), Positives = 96/274 (35%), Gaps = 43/274 (15%)
Query: 265 NITLKCLGNGNPPPE-------------EFLFYLPGQPEGIRSSNTYTLTDVRRNATGDY 311
+++L C + +P PE E +F LPG ++T L R + +G Y
Sbjct: 1763 SVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPG-------THTLQLGRARLSDSGMY 1815
Query: 312 KCSLI-----DKKSMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVW 366
C + D+K + S + + P V ++GD +SC A TV W
Sbjct: 1816 TCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTW 1875
Query: 367 MKDN-----------IRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGK 415
KD +R D G Y C+ + E ++ + TL V+
Sbjct: 1876 YKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVR---TFTLTVQVP 1932
Query: 416 PQIKMTKK---TDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSK 472
P + K + +G + C V G P P + W + V + G
Sbjct: 1933 PTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTW-LKDRMPVESSAVHGVVSRGGRLQL 1991
Query: 473 IIISPEENVTLTCTAENQLERTVNSLNVSAISIP 506
+ P + T TC AEN V+ + P
Sbjct: 1992 SRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAP 2025
Score = 48.9 bits (115), Expect = 1e-05
Identities = 56/248 (22%), Positives = 91/248 (36%), Gaps = 21/248 (8%)
Query: 264 DNITLKCLGNGNPPP-----EEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDK 318
+ + L C +G P P +E L G + + G+Y C +
Sbjct: 2772 EEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNS 2831
Query: 319 K-SMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSS- 376
S + T + V + N +++ G + C S + W KD + +
Sbjct: 2832 AGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAE 2891
Query: 377 ------PS----FSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDP 426
PS +L QDAG Y C TA V ++R LT++V ++
Sbjct: 2892 GKFTIQPSGELLVKNLEGQDAGTYTC-TAENAVGRARRRVHLTILVLPVFTTLPGDRSLR 2950
Query: 427 SGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCT 486
G + C G P P I WT+ +E+ G + +S E++ T C
Sbjct: 2951 LGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQD---GGSTLQRAAVSREDSGTYVCW 3007
Query: 487 AENQLERT 494
AEN++ RT
Sbjct: 3008 AENRVGRT 3015
Score = 48.5 bits (114), Expect = 2e-05
Identities = 88/450 (19%), Positives = 172/450 (38%), Gaps = 63/450 (14%)
Query: 98 LSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGDC 157
L++++AR SD R+ C+ V+ +++V PS I+ + L + + +
Sbjct: 844 LTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPS---ILGEELNVSVVANESVALE 900
Query: 158 ISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMP 217
+ P ++W+++G+ L P G + K + + +AD+
Sbjct: 901 CQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALL---------------QVDRADVWDA 945
Query: 218 --FTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGN 275
+TC +K + V ++ E T+ V +EG +L C G
Sbjct: 946 GHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTLTV-------REGHPTSLSCECRGV 998
Query: 276 PPPEEFLFY----LPGQPEGIRSSNTYT----LTDVRRNATGDYKC---SLIDKKSMIAS 324
P P+ LPG+ G++ + L + G Y C +++ S
Sbjct: 999 PFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQ 1058
Query: 325 TAITVH-YLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDN------IRLRSSP 377
+ V + P +V+ + C + TV W +D + L+
Sbjct: 1059 LEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQN 1118
Query: 378 SFSSLHYQDA-----GNYVCETALQEVEGLKKRESLTLIVEGKPQI-----KMTKKTDPS 427
SLH + A G Y C + + G +R+ L V P++ +T T
Sbjct: 1119 QGQSLHVERAQAAHTGRYSC--VAENLAGRAERK-FELSVLVPPELIGDLDPLTNITAAL 1175
Query: 428 GLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTL-TCT 486
T++C G P PAI+W ++ E++ + G + K+ + E++ L +C
Sbjct: 1176 HSPLTLLCEAMGIPPPAIRW--FRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCL 1233
Query: 487 AENQLERTVNSLNVSAISIP--EHDEADEI 514
A N+ + +V + P E+++ +E+
Sbjct: 1234 ASNEAGEARRNFSVEVLVPPSIENEDLEEV 1263
Score = 48.5 bits (114), Expect = 2e-05
Identities = 57/288 (19%), Positives = 105/288 (36%), Gaps = 49/288 (17%)
Query: 260 IKEGDNITLKCLGNGNPPPE----------------EFLFYLPGQP---EGIRSSNTYTL 300
+ EG + L C +G PPP+ FYL G +G+R+S+
Sbjct: 2038 VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAY 2097
Query: 301 TDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASR 360
T V N G+ L ++ T + + SG + + G+ + + C + S
Sbjct: 2098 TCVAHNPAGE-DARLHTVNVLVPPT------IKQGADGSGTLVSRPGELVTMVCPVRGSP 2150
Query: 361 NATVVWMKDNIRLRSSP-----------SFSSLHYQDAGNYVCETALQEVEGLKKRESLT 409
V W+KD + L S S + DAG + C A G+ R + T
Sbjct: 2151 PIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAA--SPAGVADR-NFT 2207
Query: 410 LIVEGKPQIKMTKKTDP----SGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYI 465
L V+ P ++ + + G + C G P P + W G + E+ P +
Sbjct: 2208 LQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSL 2267
Query: 466 NGRYYSKIIISPEENVTLTCTAENQLERTVNSLNVSAISIPEHDEADE 513
+ ++ T +C A ++ ++ + P +++ +
Sbjct: 2268 QLE-----AVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQ 2310
Score = 43.5 bits (101), Expect = 5e-04
Identities = 44/213 (20%), Positives = 78/213 (36%), Gaps = 21/213 (9%)
Query: 309 GDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTRQIGDA-LPVSCTISASRNATVVWM 367
G Y CS + + + P V R + + + + C S T+ W
Sbjct: 2732 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQ 2791
Query: 368 KDNIRLRSSPSFSSL----------HYQDAGNYVCETALQEVEGLKKRESLT----LIVE 413
K+ + + + S L +DAGNY+C + K + +I
Sbjct: 2792 KEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIEN 2851
Query: 414 GKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKI 473
G P + T+ G + C G P+P I W G + + + +G K
Sbjct: 2852 GLPDLSTTE-----GSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKN 2906
Query: 474 IISPEENVTLTCTAENQLERTVNSLNVSAISIP 506
+ + T TCTAEN + R ++++ + +P
Sbjct: 2907 LEGQDAG-TYTCTAENAVGRARRRVHLTILVLP 2938
Score = 40.0 bits (92), Expect = 0.006
Identities = 62/295 (21%), Positives = 104/295 (35%), Gaps = 37/295 (12%)
Query: 266 ITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTL--------TDVRRNATGDYKCSLID 317
+TL C G PPP + + G+ +TY L T + +G Y C L
Sbjct: 1179 LTLLCEAMGIPPPA--IRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSC-LAS 1235
Query: 318 KKSMIASTAITVHYL---DLSLNPSGEVTRQI-GDALPVSCTISASRNATVVWMKDNIRL 373
++ A +V L + EV + + G + C ++ + W KD L
Sbjct: 1236 NEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPL 1295
Query: 374 RSSPSFS-----------SLHYQDAGNYVCETALQEVEGLKKRESLTL----IVEGKPQI 418
+ + AG+Y C A E K + L I+ G
Sbjct: 1296 ARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDS 1355
Query: 419 KMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPE 478
+ T ++IC FP P I W G+ + + G + +I+ + +
Sbjct: 1356 ADEEVTVTVNNPISLICEALAFPSPNITW--MKDGAPFEASRNIQLLPGTHGLQILNAQK 1413
Query: 479 ENV-TLTCTAENQLERTVNSLNVSAISIPEHDEADEISD----ENREKVNDQAKL 528
E+ TC N+L V + +V + P + D + + E + KVN L
Sbjct: 1414 EDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTL 1468
Score = 40.0 bits (92), Expect = 0.006
Identities = 85/422 (20%), Positives = 148/422 (35%), Gaps = 80/422 (18%)
Query: 92 LSENYTLSISNARISDEKRFVCMLVT----EDNVFEA-----PTIVKVFKQPSKPEIVSK 142
L E L I ++SD R++C+ +D F P KV + EI+S+
Sbjct: 1498 LGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSR 1557
Query: 143 --------ALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDP 194
+ E + ++ P ++TWYR + PL D
Sbjct: 1558 EEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQ---PLSAG---------DE 1605
Query: 195 VTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFD---IYYPTEQVTI 251
V+ L L+ +A+ ++C + G+ +H E V I TE++
Sbjct: 1606 VSVLQG-GRVLQIPLVRAENAGRYSCKAS--NEVGEDWLHYELLVLTPPVILGDTEELVE 1662
Query: 252 QVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFY--LPGQP----EGIRSSNTYTLTDVRR 305
+V + ++L+C GNP P LP P + + ++
Sbjct: 1663 EV-----TVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV 1717
Query: 306 NATGDYKCSLIDKKSMIASTAITVHYLDLSLNPS------GEVTRQIGDALPVSCTISAS 359
Y C ++ A +A + L + + P +VT + ++ + C + A
Sbjct: 1718 ADAASYMCVAENQ----AGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAH 1773
Query: 360 RNATVVWMKDNIRLRSSPSFSSL-----------HYQDAGNYVCETALQEVEGLKKRESL 408
N V W KD+ L L D+G Y CE AL +K L
Sbjct: 1774 PNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCE-ALNAAGRDQKLVQL 1832
Query: 409 TLIV--------EGKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTE 460
+++V G + + D + LS C + P+P + W G V+ Q
Sbjct: 1833 SVLVPPAFRQAPRGPQDAVLVRVGDKAVLS----CETDALPEPTVTWYKDGQPLVLAQRT 1888
Query: 461 ES 462
++
Sbjct: 1889 QA 1890
Score = 39.3 bits (90), Expect = 0.010
Identities = 51/236 (21%), Positives = 96/236 (40%), Gaps = 44/236 (18%)
Query: 248 QVTIQVLPPKN--------AIKEGDNITLKCLGNGNPPPEEFLFYLPGQP----EGIRSS 295
+V ++VL P N A+ E ++TL+CL +G PPP + ++ QP G+ S
Sbjct: 686 EVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPP-DVSWFKGHQPVSSWMGVTVS 744
Query: 296 ---NTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYL------DLSLNPSGEVTRQI 346
+ + + G Y+C S +A + + L ++L PS +
Sbjct: 745 VDGRVLRIEQAQLSDAGSYRC----VASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLV 800
Query: 347 GDALPVSCTISASRNATVVWMKDN--IRLRSSP-----------SFSSLHYQDAGNYVCE 393
+ ++C + + + T++W+KD + +P + +S D+G Y C
Sbjct: 801 NTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSC- 859
Query: 394 TALQEVEGLKKRESLTLIVEGKPQI--KMTKKTDPSGLSKTIICHVEGFPKPAIQW 447
A+ V + R+ + L V P I + + + S + C P P + W
Sbjct: 860 VAVSAVG--EDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSW 913
Score = 36.6 bits (83), Expect = 0.065
Identities = 60/291 (20%), Positives = 110/291 (37%), Gaps = 40/291 (13%)
Query: 94 ENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPS--KPEIVSKALFLETEQL 151
+ L I+ + + DE R+ C+ + ++V P+ + +E +
Sbjct: 270 DGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLV 329
Query: 152 KKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTST-LEYKTT 210
+ L + P NITW+++G +L P VV YT L+
Sbjct: 330 QLLCEA---RGVPTPNITWFKDGALL-PTSTKVV-------------YTRGGRQLQLGRA 372
Query: 211 KADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKC 270
++ +TC + + +K D+Y P P G + L+C
Sbjct: 373 QSSDAGVYTCKASNAVGAAEKATR-----LDVYVPPTIEGAGGRPYVVKAVAGRPVALEC 427
Query: 271 LGNGNPPPEEFLFYLPGQPEGIRSSNTYTL-TD---VRRNATGDYKCSLID-KKSMIAST 325
+ G+P P ++ G P + SN L TD +R + G+ L S A
Sbjct: 428 VARGHPSPT-LSWHHEGLP--VAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGE 484
Query: 326 AITVHYLDLSLNPS-------GEVTRQIGDALPVSCTISASRNATVVWMKD 369
A+ + +++ + P G+VT +G L + C S S T+ W+++
Sbjct: 485 AVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQN 535
Score = 36.6 bits (83), Expect = 0.065
Identities = 50/228 (21%), Positives = 83/228 (36%), Gaps = 51/228 (22%)
Query: 260 IKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYT-------LTDVRRNATGDYK 312
+ +G L C G+P P+ ++ G+P ++ + + ++ G Y
Sbjct: 1266 VLDGQTAHLMCNVTGHPQPK-LTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYS 1324
Query: 313 CSLIDKKSMIASTAI---TVHY-LDLSLNPS----------GEVTRQIGDALPVSCTISA 358
C IA+ A+ T H+ L + L P+ EVT + + + + C A
Sbjct: 1325 C--------IAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALA 1376
Query: 359 SRNATVVWMKDNIRLRSSPSFSSL-----------HYQDAGNYVCETALQEVEGLKKRES 407
+ + WMKD +S + L +DAG Y C + E +K
Sbjct: 1377 FPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHV 1436
Query: 408 LTLIVE--------GKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQW 447
LI G+ +K K S L T+ C P P I+W
Sbjct: 1437 EVLIPPSISKDDPLGEVGVKEVKTKVNSTL--TLECESWAVPPPTIRW 1482
Score = 36.2 bits (82), Expect = 0.086
Identities = 68/327 (20%), Positives = 112/327 (34%), Gaps = 70/327 (21%)
Query: 156 DCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQ 215
DC D P ++ W ++G L ++M P + Y +L K +A
Sbjct: 2047 DC-EADGQPPPDVAWLKDGSPLG-----------QDMGPHLRFYLDGGSLVLKGLRASDA 2094
Query: 216 MPFTCSVTYYGPSGQKT-IHSEQAVFDIYYPTEQVTIQVLPPKN-----------AIKEG 263
+TC + P+G+ +H T+ VL P + G
Sbjct: 2095 GAYTCVA--HNPAGEDARLH---------------TVNVLVPPTIKQGADGSGTLVSRPG 2137
Query: 264 DNITLKCLGNGNPPPEEFLFYLPGQPEGIR-------SSNTYTLTDVRRNATGDYKCSLI 316
+ +T+ C G+PP + G P + S +T ++ V+ G + C
Sbjct: 2138 ELVTMVCPVRGSPPIH-VSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAA 2196
Query: 317 DKKSMIASTAITVHYLDLSLNP---SGEVTRQIGDALPVSCTISASRNATVVWMKDNIRL 373
+ + L P +V G + + C V WMKD L
Sbjct: 2197 SPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPL 2256
Query: 374 RS-------SPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDP 426
S S ++ D+G Y C + E R L V P I+ + + P
Sbjct: 2257 LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEA---RRHFQLTVMEPPHIEDSGQ--P 2311
Query: 427 SGLSKT------IICHVEGFPKPAIQW 447
+ LS T ++C +G P+P I W
Sbjct: 2312 TELSLTPGAPMELLCDAQGTPQPNITW 2338
Score = 35.8 bits (81), Expect = 0.11
Identities = 70/307 (22%), Positives = 106/307 (34%), Gaps = 55/307 (17%)
Query: 164 PDGNITWYRNGKVLHPLEG---AVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTC 220
P NITW+++G+ L LE A ++ ++ T L + K+ + +Q P
Sbjct: 2332 PQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAP--- 2388
Query: 221 SVTYYGPSGQKTI---HSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPP 277
GP G + + Q V + +++ P D I L+ + P
Sbjct: 2389 -PNIVGPRGPRFVVGLAPGQLVL-------ECSVEAEPAPKITWHRDGIVLQEDAHTQFP 2440
Query: 278 PEEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLN 337
E +L Q S Y+ T RNA G S + + +H + +
Sbjct: 2441 --ERGRFLQLQALSTADSGDYSCT--ARNAAG----------STSVAFRVEIHTVPTIRS 2486
Query: 338 PSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRL-RSSPSFSSLH----------YQD 386
V + + C V W KD + L SP F L QD
Sbjct: 2487 GPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQD 2546
Query: 387 AGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDPSGLSKT------IICHVEGF 440
AG+Y+C L R+ L V P I PS L+ T + C G
Sbjct: 2547 AGHYLC---LASNSAGSDRQGRDLRVLEPPAI----APSPSNLTLTAHTPALLPCEASGS 2599
Query: 441 PKPAIQW 447
PKP + W
Sbjct: 2600 PKPLVVW 2606
Score = 35.4 bits (80), Expect = 0.15
Identities = 25/72 (34%), Positives = 37/72 (51%), Gaps = 7/72 (9%)
Query: 380 SSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMT-KKTDPSGL---SKTIIC 435
+S+ D+G+Y C+ A EV +R L + V P I+ +K + SG+ S T+ C
Sbjct: 62 ASVSPADSGDYECQ-ATNEVGSTSRRAKLVVYVP--PSIREDGRKANVSGMAGQSLTLEC 118
Query: 436 HVEGFPKPAIQW 447
GFP P I W
Sbjct: 119 DANGFPVPEIVW 130
Score = 33.9 bits (76), Expect = 0.42
Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 4/89 (4%)
Query: 285 LPGQPE-GIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNPSG--- 340
L GQP + + L V +GDY+C ++ + A V Y+ S+ G
Sbjct: 45 LHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKA 104
Query: 341 EVTRQIGDALPVSCTISASRNATVVWMKD 369
V+ G +L + C + +VW+KD
Sbjct: 105 NVSGMAGQSLTLECDANGFPVPEIVWLKD 133
Score = 33.9 bits (76), Expect = 0.42
Identities = 82/383 (21%), Positives = 132/383 (34%), Gaps = 51/383 (13%)
Query: 94 ENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPS--KPEIVSKALFLETEQL 151
EN + + R+ D + C+ + E V+V P+ P + L QL
Sbjct: 2349 ENNSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQL 2408
Query: 152 KKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTK 211
+ +C S ++ P ITW+R+G VL + D TQ L+ +
Sbjct: 2409 --VLEC-SVEAEPAPKITWHRDGIVL-------------QEDAHTQFPERGRFLQLQALS 2452
Query: 212 ADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCL 271
++C+ + S F + T TI+ PP + L C
Sbjct: 2453 TADSGDYSCTA-------RNAAGSTSVAFRVEIHTVP-TIRSGPPAVNVSVNQTALLPCQ 2504
Query: 272 GNGNPPP-----EEFLFYLPGQPE-GIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIAST 325
+G P P ++ + P P I + + V G Y C L +
Sbjct: 2505 ADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLC-LASNSAGSDRQ 2563
Query: 326 AITVHYLD---LSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRL--------- 373
+ L+ ++ +PS AL + C S S VVW KD +L
Sbjct: 2564 GRDLRVLEPPAIAPSPSNLTLTAHTPAL-LPCEASGSPKPLVVWWKDGQKLDFRLQQGAY 2622
Query: 374 RSSPSFSSLHY----QDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDPSGL 429
R PS + L QD+ + C + EV + +T+ V T T
Sbjct: 2623 RLLPSNALLLTAPGPQDSAQFECVVS-NEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMA 2681
Query: 430 SKTIICHVEGFPKPAIQWTITGS 452
+ CH G P P + W+ G+
Sbjct: 2682 PVVLTCHSTGIPAPTVSWSKAGA 2704
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 60.1 bits (144), Expect = 6e-09
Identities = 65/308 (21%), Positives = 116/308 (37%), Gaps = 46/308 (14%)
Query: 164 PDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVT 223
P+ NITW ++G+ + EG I + L K + +TC+
Sbjct: 4065 PEPNITWDKDGQPVSGAEGKFTI-------------QPSGELLVKNLEGQDAGTYTCTAE 4111
Query: 224 YYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLF 283
++ +H V ++ LP +++ GD + L+C G+P P +
Sbjct: 4112 NAVGRARRRVHLTILVLPVF--------TTLPGDRSLRLGDRLWLRCAARGSPTP-RIGW 4162
Query: 284 YLPGQP--EGIR---SSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLD---LS 335
+ +P EG+ +T V R +G Y C ++ + + VH + L
Sbjct: 4163 TVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSF-VHVKEAPVLQ 4221
Query: 336 LNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSSP----------SFSSLHYQ 385
+ +G ++ + C + + W+KD + LR S +
Sbjct: 4222 GEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERD 4281
Query: 386 DAGNYVCETALQEVEGLKKRESLTLIVEGKP--QIKMTKKTDPSGLSKTIICHVEGFPKP 443
DAG Y C L E E ++ + L+++ P Q++ T SG + C G P P
Sbjct: 4282 DAGRYQC---LAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTP 4338
Query: 444 AIQWTITG 451
I+W G
Sbjct: 4339 TIEWLQAG 4346
Score = 54.3 bits (129), Expect = 3e-07
Identities = 60/274 (21%), Positives = 96/274 (35%), Gaps = 43/274 (15%)
Query: 265 NITLKCLGNGNPPPE-------------EFLFYLPGQPEGIRSSNTYTLTDVRRNATGDY 311
+++L C + +P PE E +F LPG ++T L R + +G Y
Sbjct: 2954 SVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPG-------THTLQLGRARLSDSGMY 3006
Query: 312 KCSLI-----DKKSMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVW 366
C + D+K + S + + P V ++GD +SC A TV W
Sbjct: 3007 TCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTW 3066
Query: 367 MKDN-----------IRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGK 415
KD +R D G Y C+ + E ++ + TL V+
Sbjct: 3067 YKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVR---TFTLTVQVP 3123
Query: 416 PQIKMTKK---TDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSK 472
P + K + +G + C V G P P + W + V + G
Sbjct: 3124 PTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTW-LKDRMPVESSAVHGVVSRGGRLQL 3182
Query: 473 IIISPEENVTLTCTAENQLERTVNSLNVSAISIP 506
+ P + T TC AEN V+ + P
Sbjct: 3183 SRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAP 3216
Score = 49.3 bits (116), Expect = 1e-05
Identities = 57/229 (24%), Positives = 87/229 (37%), Gaps = 40/229 (17%)
Query: 248 QVTIQVLPPKNAIKE--GDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTDVRR 305
QV QV P +K G+ + L C+ GNP P+ +G + +R
Sbjct: 1117 QVPPQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQGSVHFAAIRT 1176
Query: 306 NATGDYKCSLIDKKSMIASTAITVHYLDL----SLNPSGEVTRQIGDALPVSCTISASRN 361
+ G Y+C + + A + + L+ + SG + R G+ + C +
Sbjct: 1177 SDAGRYRCEASNSAGVDA-WEVELRVLEPPHWGADETSGLLERVAGENASLPCPARGTPK 1235
Query: 362 ATVVWMKDNIRLRSSPSFSSLHYQ-------------------DAGNYVCETALQEVEGL 402
V W R PS LH Q D+G+Y C+ A EV
Sbjct: 1236 PQVTW-------RKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQ-ATNEVGST 1287
Query: 403 KKRESLTLIVEGKPQIKMT-KKTDPSGL---SKTIICHVEGFPKPAIQW 447
+R L + V P I+ +K + SG+ S T+ C GFP P I W
Sbjct: 1288 SRRAKLVVYVP--PSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVW 1334
Score = 48.9 bits (115), Expect = 1e-05
Identities = 56/248 (22%), Positives = 91/248 (36%), Gaps = 21/248 (8%)
Query: 264 DNITLKCLGNGNPPP-----EEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDK 318
+ + L C +G P P +E L G + + G+Y C +
Sbjct: 3963 EEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNS 4022
Query: 319 K-SMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSS- 376
S + T + V + N +++ G + C S + W KD + +
Sbjct: 4023 AGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAE 4082
Query: 377 ------PS----FSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDP 426
PS +L QDAG Y C TA V ++R LT++V ++
Sbjct: 4083 GKFTIQPSGELLVKNLEGQDAGTYTC-TAENAVGRARRRVHLTILVLPVFTTLPGDRSLR 4141
Query: 427 SGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCT 486
G + C G P P I WT+ +E+ G + +S E++ T C
Sbjct: 4142 LGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQD---GGSTLQRAAVSREDSGTYVCW 4198
Query: 487 AENQLERT 494
AEN++ RT
Sbjct: 4199 AENRVGRT 4206
Score = 48.5 bits (114), Expect = 2e-05
Identities = 88/450 (19%), Positives = 172/450 (38%), Gaps = 63/450 (14%)
Query: 98 LSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGDC 157
L++++AR SD R+ C+ V+ +++V PS I+ + L + + +
Sbjct: 2035 LTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPS---ILGEELNVSVVANESVALE 2091
Query: 158 ISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMP 217
+ P ++W+++G+ L P G + K + + +AD+
Sbjct: 2092 CQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALL---------------QVDRADVWDA 2136
Query: 218 --FTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGN 275
+TC +K + V ++ E T+ V +EG +L C G
Sbjct: 2137 GHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTV-------REGHPTSLSCECRGV 2189
Query: 276 PPPEEFLFY----LPGQPEGIRSSNTYT----LTDVRRNATGDYKC---SLIDKKSMIAS 324
P P+ LPG+ G++ + L + G Y C +++ S
Sbjct: 2190 PFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQ 2249
Query: 325 TAITVH-YLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDN------IRLRSSP 377
+ V + P +V+ + C + TV W +D + L+
Sbjct: 2250 LEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQN 2309
Query: 378 SFSSLHYQDA-----GNYVCETALQEVEGLKKRESLTLIVEGKPQI-----KMTKKTDPS 427
SLH + A G Y C + + G +R+ L V P++ +T T
Sbjct: 2310 QGQSLHVERAQAAHTGRYSC--VAENLAGRAERK-FELSVLVPPELIGDLDPLTNITAAL 2366
Query: 428 GLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTL-TCT 486
T++C G P PAI+W ++ E++ + G + K+ + E++ L +C
Sbjct: 2367 HSPLTLLCEAMGIPPPAIRW--FRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCL 2424
Query: 487 AENQLERTVNSLNVSAISIP--EHDEADEI 514
A N+ + +V + P E+++ +E+
Sbjct: 2425 ASNEAGEARRNFSVEVLVPPSIENEDLEEV 2454
Score = 48.5 bits (114), Expect = 2e-05
Identities = 57/288 (19%), Positives = 105/288 (36%), Gaps = 49/288 (17%)
Query: 260 IKEGDNITLKCLGNGNPPPE----------------EFLFYLPGQP---EGIRSSNTYTL 300
+ EG + L C +G PPP+ FYL G +G+R+S+
Sbjct: 3229 VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAY 3288
Query: 301 TDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASR 360
T V N G+ L ++ T + + SG + + G+ + + C + S
Sbjct: 3289 TCVAHNPAGE-DARLHTVNVLVPPT------IKQGADGSGTLVSRPGELVTMVCPVRGSP 3341
Query: 361 NATVVWMKDNIRLRSSP-----------SFSSLHYQDAGNYVCETALQEVEGLKKRESLT 409
V W+KD + L S S + DAG + C A G+ R + T
Sbjct: 3342 PIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAA--SPAGVADR-NFT 3398
Query: 410 LIVEGKPQIKMTKKTDP----SGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYI 465
L V+ P ++ + + G + C G P P + W G + E+ P +
Sbjct: 3399 LQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSL 3458
Query: 466 NGRYYSKIIISPEENVTLTCTAENQLERTVNSLNVSAISIPEHDEADE 513
+ ++ T +C A ++ ++ + P +++ +
Sbjct: 3459 QLE-----AVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQ 3501
Score = 48.1 bits (113), Expect = 2e-05
Identities = 95/449 (21%), Positives = 148/449 (32%), Gaps = 75/449 (16%)
Query: 89 RLNLSENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLET 148
R+++ TL I D + C E + T+ + P V+ + +
Sbjct: 653 RIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGT-DQETVTLYYTDPPSVSAVNAVVLVAV 711
Query: 149 EQLKKLGDCISEDSYPDGNITWYRNG--KVLHP---LEGAVVIIFKKEMDPVTQLYTMTS 203
+ L P + WYR G +L P G + I +E D T YT +
Sbjct: 712 GEEAVL--VCEASGVPPPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGT--YTCRA 767
Query: 204 TLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEG 263
E A+IQ+ H+ Q + LP ++ G
Sbjct: 768 VNELGDASAEIQLAVG--------------HAPQ-------------LTELPRDVTVELG 800
Query: 264 DNITLKCLGNGNPPPEEFLFYLPGQPEGIR------------SSNTYTLTDVRRNATGDY 311
+ L C G PPP GQP G+R S V Y
Sbjct: 801 RSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPY 860
Query: 312 KC---SLIDKKSMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVV-WM 367
C ++ K A +T H + + V G + + C + A R W+
Sbjct: 861 VCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWL 920
Query: 368 KDNIRLRSSPSFS-----SLHY-----QDAGNYVCETALQEVEGLKKRESLTLIVEGKPQ 417
KD L S SLH + AG Y C G + R+ + L+V+ P+
Sbjct: 921 KDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVAT--NTAGSQHRD-VELVVQVPPR 977
Query: 418 IK--MTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIII 475
I T G+ ++ C G P P I WT + T P+ N ++I
Sbjct: 978 IHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNA----LTSRGPHYNVSKEGTLLI 1033
Query: 476 ---SPEENVTLTCTAENQLERTVNSLNVS 501
S ++ CTA N + + + +S
Sbjct: 1034 AQPSAQDAGAYVCTATNTVGFSSQEMRLS 1062
Score = 47.0 bits (110), Expect = 5e-05
Identities = 44/215 (20%), Positives = 85/215 (39%), Gaps = 15/215 (6%)
Query: 291 GIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTRQ-IGDA 349
G+ S + L V+ +G Y+C+ + + + + + P V + +G+A
Sbjct: 1077 GLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEA 1136
Query: 350 LPVSCTISASRNATVVWMKDNIRL-----RSSPSFSSLHYQDAGNYVCETALQEVEGLKK 404
L ++C + + W KD + L + S F+++ DAG Y CE + G+
Sbjct: 1137 LDLNCVAEGNPEPQLSWSKDGVVLQGRGPQGSVHFAAIRTSDAGRYRCEAS--NSAGVDA 1194
Query: 405 RESLTLIVEGKPQIKMTKKTD-----PSGLSKTIICHVEGFPKPAIQWTITGSGSVINQT 459
E ++E P +T +G + ++ C G PKP + W S ++
Sbjct: 1195 WEVELRVLE--PPHWGADETSGLLERVAGENASLPCPARGTPKPQVTWRKGPSSEPLHGQ 1252
Query: 460 EESPYINGRYYSKIIISPEENVTLTCTAENQLERT 494
+ +SP ++ C A N++ T
Sbjct: 1253 PGVAVLEEGSLFLASVSPADSGDYECQATNEVGST 1287
Score = 44.7 bits (104), Expect = 2e-04
Identities = 50/225 (22%), Positives = 81/225 (36%), Gaps = 41/225 (18%)
Query: 263 GDNITLKCLGNGNPPPEEFLFYLP------GQPE-GIRSSNTYTLTDVRRNATGDYKCSL 315
G+N +L C G P P+ P GQP + + L V +GDY+C
Sbjct: 1221 GENASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQA 1280
Query: 316 IDKKSMIASTAITVHYLDLSLNPSGE---VTRQIGDALPVSCTISASRNATVVWMKDNIR 372
++ + A V Y+ S+ G V+ G +L + C + +VW+KD
Sbjct: 1281 TNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQL 1340
Query: 373 L---------------------RSSPSFSSLHYQ-----DAGNYVCETALQEVEGLKKRE 406
+ R SLH+ D+G Y C Q G +R+
Sbjct: 1341 VGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQ--AGTAQRD 1398
Query: 407 SLTLIVEGKPQIKMTKKTDPSGLSKTII---CHVEGFPKPAIQWT 448
L++ + + GL+ + C G P P ++WT
Sbjct: 1399 FHLLVLTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWT 1443
Score = 43.5 bits (101), Expect = 5e-04
Identities = 45/200 (22%), Positives = 77/200 (38%), Gaps = 25/200 (12%)
Query: 309 GDYKCSLIDKKSM-IASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWM 367
G Y+C+ + + A I V L P+ VT G+ +SC + + W+
Sbjct: 492 GTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWV 551
Query: 368 KDNIRLRSSPS-----------FSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKP 416
+D L +S S + D G Y C + G+ R S+ L+V P
Sbjct: 552 RDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVAS--NANGVT-RASVWLLVREAP 608
Query: 417 QIKMTKKTD--PSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKII 474
Q+ + + G+ + C G+P P I W+ +E I+ +I
Sbjct: 609 QVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQA-----LQEDSRIHVDAQGTLI 663
Query: 475 I---SPEENVTLTCTAENQL 491
I +PE+ +C A N++
Sbjct: 664 IQGVAPEDAGNYSCQATNEV 683
Score = 43.5 bits (101), Expect = 5e-04
Identities = 44/213 (20%), Positives = 78/213 (36%), Gaps = 21/213 (9%)
Query: 309 GDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTRQIGDA-LPVSCTISASRNATVVWM 367
G Y CS + + + P V R + + + + C S T+ W
Sbjct: 3923 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQ 3982
Query: 368 KDNIRLRSSPSFSSL----------HYQDAGNYVCETALQEVEGLKKRESLT----LIVE 413
K+ + + + S L +DAGNY+C + K + +I
Sbjct: 3983 KEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIEN 4042
Query: 414 GKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKI 473
G P + T+ G + C G P+P I W G + + + +G K
Sbjct: 4043 GLPDLSTTE-----GSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKN 4097
Query: 474 IISPEENVTLTCTAENQLERTVNSLNVSAISIP 506
+ + T TCTAEN + R ++++ + +P
Sbjct: 4098 LEGQDAG-TYTCTAENAVGRARRRVHLTILVLP 4129
Score = 40.0 bits (92), Expect = 0.006
Identities = 62/295 (21%), Positives = 104/295 (35%), Gaps = 37/295 (12%)
Query: 266 ITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTL--------TDVRRNATGDYKCSLID 317
+TL C G PPP + + G+ +TY L T + +G Y C L
Sbjct: 2370 LTLLCEAMGIPPPA--IRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSC-LAS 2426
Query: 318 KKSMIASTAITVHYL---DLSLNPSGEVTRQI-GDALPVSCTISASRNATVVWMKDNIRL 373
++ A +V L + EV + + G + C ++ + W KD L
Sbjct: 2427 NEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPL 2486
Query: 374 RSSPSFS-----------SLHYQDAGNYVCETALQEVEGLKKRESLTL----IVEGKPQI 418
+ + AG+Y C A E K + L I+ G
Sbjct: 2487 ARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDS 2546
Query: 419 KMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPE 478
+ T ++IC FP P I W G+ + + G + +I+ + +
Sbjct: 2547 ADEEVTVTVNNPISLICEALAFPSPNITW--MKDGAPFEASRNIQLLPGTHGLQILNAQK 2604
Query: 479 ENV-TLTCTAENQLERTVNSLNVSAISIPEHDEADEISD----ENREKVNDQAKL 528
E+ TC N+L V + +V + P + D + + E + KVN L
Sbjct: 2605 EDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTL 2659
Score = 40.0 bits (92), Expect = 0.006
Identities = 85/422 (20%), Positives = 148/422 (35%), Gaps = 80/422 (18%)
Query: 92 LSENYTLSISNARISDEKRFVCMLVT----EDNVFEA-----PTIVKVFKQPSKPEIVSK 142
L E L I ++SD R++C+ +D F P KV + EI+S+
Sbjct: 2689 LGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSR 2748
Query: 143 --------ALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDP 194
+ E + ++ P ++TWYR + PL D
Sbjct: 2749 EEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQ---PLSAG---------DE 2796
Query: 195 VTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFD---IYYPTEQVTI 251
V+ L L+ +A+ ++C + G+ +H E V I TE++
Sbjct: 2797 VSVLQG-GRVLQIPLVRAENAGRYSCKAS--NEVGEDWLHYELLVLTPPVILGDTEELVE 2853
Query: 252 QVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFY--LPGQP----EGIRSSNTYTLTDVRR 305
+V + ++L+C GNP P LP P + + ++
Sbjct: 2854 EV-----TVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV 2908
Query: 306 NATGDYKCSLIDKKSMIASTAITVHYLDLSLNPS------GEVTRQIGDALPVSCTISAS 359
Y C ++ A +A + L + + P +VT + ++ + C + A
Sbjct: 2909 ADAASYMCVAENQ----AGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAH 2964
Query: 360 RNATVVWMKDNIRLRSSPSFSSL-----------HYQDAGNYVCETALQEVEGLKKRESL 408
N V W KD+ L L D+G Y CE AL +K L
Sbjct: 2965 PNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCE-ALNAAGRDQKLVQL 3023
Query: 409 TLIV--------EGKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTE 460
+++V G + + D + LS C + P+P + W G V+ Q
Sbjct: 3024 SVLVPPAFRQAPRGPQDAVLVRVGDKAVLS----CETDALPEPTVTWYKDGQPLVLAQRT 3079
Query: 461 ES 462
++
Sbjct: 3080 QA 3081
Score = 39.3 bits (90), Expect = 0.010
Identities = 51/236 (21%), Positives = 96/236 (40%), Gaps = 44/236 (18%)
Query: 248 QVTIQVLPPKN--------AIKEGDNITLKCLGNGNPPPEEFLFYLPGQP----EGIRSS 295
+V ++VL P N A+ E ++TL+CL +G PPP + ++ QP G+ S
Sbjct: 1877 EVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPP-DVSWFKGHQPVSSWMGVTVS 1935
Query: 296 ---NTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYL------DLSLNPSGEVTRQI 346
+ + + G Y+C S +A + + L ++L PS +
Sbjct: 1936 VDGRVLRIEQAQLSDAGSYRC----VASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLV 1991
Query: 347 GDALPVSCTISASRNATVVWMKDN--IRLRSSP-----------SFSSLHYQDAGNYVCE 393
+ ++C + + + T++W+KD + +P + +S D+G Y C
Sbjct: 1992 NTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSC- 2050
Query: 394 TALQEVEGLKKRESLTLIVEGKPQI--KMTKKTDPSGLSKTIICHVEGFPKPAIQW 447
A+ V + R+ + L V P I + + + S + C P P + W
Sbjct: 2051 VAVSAVG--EDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSW 2104
Score = 36.6 bits (83), Expect = 0.065
Identities = 60/291 (20%), Positives = 110/291 (37%), Gaps = 40/291 (13%)
Query: 94 ENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPS--KPEIVSKALFLETEQL 151
+ L I+ + + DE R+ C+ + ++V P+ + +E +
Sbjct: 1461 DGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLV 1520
Query: 152 KKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTST-LEYKTT 210
+ L + P NITW+++G +L P VV YT L+
Sbjct: 1521 QLLCEA---RGVPTPNITWFKDGALL-PTSTKVV-------------YTRGGRQLQLGRA 1563
Query: 211 KADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKC 270
++ +TC + + +K D+Y P P G + L+C
Sbjct: 1564 QSSDAGVYTCKASNAVGAAEKATR-----LDVYVPPTIEGAGGRPYVVKAVAGRPVALEC 1618
Query: 271 LGNGNPPPEEFLFYLPGQPEGIRSSNTYTL-TD---VRRNATGDYKCSLID-KKSMIAST 325
+ G+P P ++ G P + SN L TD +R + G+ L S A
Sbjct: 1619 VARGHPSPT-LSWHHEGLP--VAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGE 1675
Query: 326 AITVHYLDLSLNPS-------GEVTRQIGDALPVSCTISASRNATVVWMKD 369
A+ + +++ + P G+VT +G L + C S S T+ W+++
Sbjct: 1676 AVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQN 1726
Score = 36.6 bits (83), Expect = 0.065
Identities = 50/228 (21%), Positives = 83/228 (36%), Gaps = 51/228 (22%)
Query: 260 IKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYT-------LTDVRRNATGDYK 312
+ +G L C G+P P+ ++ G+P ++ + + ++ G Y
Sbjct: 2457 VLDGQTAHLMCNVTGHPQPK-LTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYS 2515
Query: 313 CSLIDKKSMIASTAI---TVHY-LDLSLNPS----------GEVTRQIGDALPVSCTISA 358
C IA+ A+ T H+ L + L P+ EVT + + + + C A
Sbjct: 2516 C--------IAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALA 2567
Query: 359 SRNATVVWMKDNIRLRSSPSFSSL-----------HYQDAGNYVCETALQEVEGLKKRES 407
+ + WMKD +S + L +DAG Y C + E +K
Sbjct: 2568 FPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHV 2627
Query: 408 LTLIVE--------GKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQW 447
LI G+ +K K S L T+ C P P I+W
Sbjct: 2628 EVLIPPSISKDDPLGEVGVKEVKTKVNSTL--TLECESWAVPPPTIRW 2673
Score = 36.2 bits (82), Expect = 0.086
Identities = 68/327 (20%), Positives = 112/327 (34%), Gaps = 70/327 (21%)
Query: 156 DCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQ 215
DC D P ++ W ++G L ++M P + Y +L K +A
Sbjct: 3238 DC-EADGQPPPDVAWLKDGSPLG-----------QDMGPHLRFYLDGGSLVLKGLRASDA 3285
Query: 216 MPFTCSVTYYGPSGQKT-IHSEQAVFDIYYPTEQVTIQVLPPKN-----------AIKEG 263
+TC + P+G+ +H T+ VL P + G
Sbjct: 3286 GAYTCVA--HNPAGEDARLH---------------TVNVLVPPTIKQGADGSGTLVSRPG 3328
Query: 264 DNITLKCLGNGNPPPEEFLFYLPGQPEGIR-------SSNTYTLTDVRRNATGDYKCSLI 316
+ +T+ C G+PP + G P + S +T ++ V+ G + C
Sbjct: 3329 ELVTMVCPVRGSPPIH-VSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAA 3387
Query: 317 DKKSMIASTAITVHYLDLSLNP---SGEVTRQIGDALPVSCTISASRNATVVWMKDNIRL 373
+ + L P +V G + + C V WMKD L
Sbjct: 3388 SPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPL 3447
Query: 374 RS-------SPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDP 426
S S ++ D+G Y C + E R L V P I+ + + P
Sbjct: 3448 LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEA---RRHFQLTVMEPPHIEDSGQ--P 3502
Query: 427 SGLSKT------IICHVEGFPKPAIQW 447
+ LS T ++C +G P+P I W
Sbjct: 3503 TELSLTPGAPMELLCDAQGTPQPNITW 3529
Score = 35.8 bits (81), Expect = 0.11
Identities = 70/307 (22%), Positives = 106/307 (34%), Gaps = 55/307 (17%)
Query: 164 PDGNITWYRNGKVLHPLEG---AVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTC 220
P NITW+++G+ L LE A ++ ++ T L + K+ + +Q P
Sbjct: 3523 PQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAP--- 3579
Query: 221 SVTYYGPSGQKTI---HSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPP 277
GP G + + Q V + +++ P D I L+ + P
Sbjct: 3580 -PNIVGPRGPRFVVGLAPGQLVL-------ECSVEAEPAPKITWHRDGIVLQEDAHTQFP 3631
Query: 278 PEEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLN 337
E +L Q S Y+ T RNA G S + + +H + +
Sbjct: 3632 --ERGRFLQLQALSTADSGDYSCT--ARNAAG----------STSVAFRVEIHTVPTIRS 3677
Query: 338 PSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRL-RSSPSFSSLH----------YQD 386
V + + C V W KD + L SP F L QD
Sbjct: 3678 GPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQD 3737
Query: 387 AGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDPSGLSKT------IICHVEGF 440
AG+Y+C L R+ L V P I PS L+ T + C G
Sbjct: 3738 AGHYLC---LASNSAGSDRQGRDLRVLEPPAI----APSPSNLTLTAHTPALLPCEASGS 3790
Query: 441 PKPAIQW 447
PKP + W
Sbjct: 3791 PKPLVVW 3797
Score = 33.9 bits (76), Expect = 0.42
Identities = 82/383 (21%), Positives = 132/383 (34%), Gaps = 51/383 (13%)
Query: 94 ENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPS--KPEIVSKALFLETEQL 151
EN + + R+ D + C+ + E V+V P+ P + L QL
Sbjct: 3540 ENNSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQL 3599
Query: 152 KKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTK 211
+ +C S ++ P ITW+R+G VL + D TQ L+ +
Sbjct: 3600 --VLEC-SVEAEPAPKITWHRDGIVL-------------QEDAHTQFPERGRFLQLQALS 3643
Query: 212 ADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCL 271
++C+ + S F + T TI+ PP + L C
Sbjct: 3644 TADSGDYSCTA-------RNAAGSTSVAFRVEIHTVP-TIRSGPPAVNVSVNQTALLPCQ 3695
Query: 272 GNGNPPP-----EEFLFYLPGQPE-GIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIAST 325
+G P P ++ + P P I + + V G Y C L +
Sbjct: 3696 ADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLC-LASNSAGSDRQ 3754
Query: 326 AITVHYLD---LSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRL--------- 373
+ L+ ++ +PS AL + C S S VVW KD +L
Sbjct: 3755 GRDLRVLEPPAIAPSPSNLTLTAHTPAL-LPCEASGSPKPLVVWWKDGQKLDFRLQQGAY 3813
Query: 374 RSSPSFSSLHY----QDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDPSGL 429
R PS + L QD+ + C + EV + +T+ V T T
Sbjct: 3814 RLLPSNALLLTAPGPQDSAQFECVVS-NEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMA 3872
Query: 430 SKTIICHVEGFPKPAIQWTITGS 452
+ CH G P P + W+ G+
Sbjct: 3873 PVVLTCHSTGIPAPTVSWSKAGA 3895
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 60.1 bits (144), Expect = 6e-09
Identities = 65/308 (21%), Positives = 116/308 (37%), Gaps = 46/308 (14%)
Query: 164 PDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVT 223
P+ NITW ++G+ + EG I + L K + +TC+
Sbjct: 2783 PEPNITWDKDGQPVSGAEGKFTI-------------QPSGELLVKNLEGQDAGTYTCTAE 2829
Query: 224 YYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLF 283
++ +H V ++ LP +++ GD + L+C G+P P +
Sbjct: 2830 NAVGRARRRVHLTILVLPVF--------TTLPGDRSLRLGDRLWLRCAARGSPTP-RIGW 2880
Query: 284 YLPGQP--EGIR---SSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLD---LS 335
+ +P EG+ +T V R +G Y C ++ + + VH + L
Sbjct: 2881 TVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSF-VHVKEAPVLQ 2939
Query: 336 LNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSSP----------SFSSLHYQ 385
+ +G ++ + C + + W+KD + LR S +
Sbjct: 2940 GEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERD 2999
Query: 386 DAGNYVCETALQEVEGLKKRESLTLIVEGKP--QIKMTKKTDPSGLSKTIICHVEGFPKP 443
DAG Y C L E E ++ + L+++ P Q++ T SG + C G P P
Sbjct: 3000 DAGRYQC---LAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTP 3056
Query: 444 AIQWTITG 451
I+W G
Sbjct: 3057 TIEWLQAG 3064
Score = 54.3 bits (129), Expect = 3e-07
Identities = 60/274 (21%), Positives = 96/274 (35%), Gaps = 43/274 (15%)
Query: 265 NITLKCLGNGNPPPE-------------EFLFYLPGQPEGIRSSNTYTLTDVRRNATGDY 311
+++L C + +P PE E +F LPG ++T L R + +G Y
Sbjct: 1672 SVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPG-------THTLQLGRARLSDSGMY 1724
Query: 312 KCSLI-----DKKSMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVW 366
C + D+K + S + + P V ++GD +SC A TV W
Sbjct: 1725 TCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTW 1784
Query: 367 MKDN-----------IRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGK 415
KD +R D G Y C+ + E ++ + TL V+
Sbjct: 1785 YKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVR---TFTLTVQVP 1841
Query: 416 PQIKMTKK---TDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSK 472
P + K + +G + C V G P P + W + V + G
Sbjct: 1842 PTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTW-LKDRMPVESSAVHGVVSRGGRLQL 1900
Query: 473 IIISPEENVTLTCTAENQLERTVNSLNVSAISIP 506
+ P + T TC AEN V+ + P
Sbjct: 1901 SRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAP 1934
Score = 48.9 bits (115), Expect = 1e-05
Identities = 56/248 (22%), Positives = 91/248 (36%), Gaps = 21/248 (8%)
Query: 264 DNITLKCLGNGNPPP-----EEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDK 318
+ + L C +G P P +E L G + + G+Y C +
Sbjct: 2681 EEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNS 2740
Query: 319 K-SMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSS- 376
S + T + V + N +++ G + C S + W KD + +
Sbjct: 2741 AGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAE 2800
Query: 377 ------PS----FSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDP 426
PS +L QDAG Y C TA V ++R LT++V ++
Sbjct: 2801 GKFTIQPSGELLVKNLEGQDAGTYTC-TAENAVGRARRRVHLTILVLPVFTTLPGDRSLR 2859
Query: 427 SGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCT 486
G + C G P P I WT+ +E+ G + +S E++ T C
Sbjct: 2860 LGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQD---GGSTLQRAAVSREDSGTYVCW 2916
Query: 487 AENQLERT 494
AEN++ RT
Sbjct: 2917 AENRVGRT 2924
Score = 48.5 bits (114), Expect = 2e-05
Identities = 57/288 (19%), Positives = 105/288 (36%), Gaps = 49/288 (17%)
Query: 260 IKEGDNITLKCLGNGNPPPE----------------EFLFYLPGQP---EGIRSSNTYTL 300
+ EG + L C +G PPP+ FYL G +G+R+S+
Sbjct: 1947 VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAY 2006
Query: 301 TDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASR 360
T V N G+ L ++ T + + SG + + G+ + + C + S
Sbjct: 2007 TCVAHNPAGE-DARLHTVNVLVPPT------IKQGADGSGTLVSRPGELVTMVCPVRGSP 2059
Query: 361 NATVVWMKDNIRLRSSP-----------SFSSLHYQDAGNYVCETALQEVEGLKKRESLT 409
V W+KD + L S S + DAG + C A G+ R + T
Sbjct: 2060 PIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAA--SPAGVADR-NFT 2116
Query: 410 LIVEGKPQIKMTKKTDP----SGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYI 465
L V+ P ++ + + G + C G P P + W G + E+ P +
Sbjct: 2117 LQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSL 2176
Query: 466 NGRYYSKIIISPEENVTLTCTAENQLERTVNSLNVSAISIPEHDEADE 513
+ ++ T +C A ++ ++ + P +++ +
Sbjct: 2177 QLE-----AVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQ 2219
Score = 47.8 bits (112), Expect = 3e-05
Identities = 88/450 (19%), Positives = 171/450 (38%), Gaps = 63/450 (14%)
Query: 98 LSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGDC 157
L++++AR SD R+ C+ V+ +++V PS I+ + L + + +
Sbjct: 753 LTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPS---ILGEELNVSVVANESVALE 809
Query: 158 ISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMP 217
+ P ++W+++G+ L P G + K + + +AD+
Sbjct: 810 CQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALL---------------QVDRADVWDA 854
Query: 218 --FTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGN 275
+TC +K + V ++ E T+ V +EG L C G
Sbjct: 855 GHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTV-------REGHPTRLSCECRGV 907
Query: 276 PPPEEFLFY----LPGQPEGIRSSNTYT----LTDVRRNATGDYKC---SLIDKKSMIAS 324
P P+ LPG+ G++ + L + G Y C +++ S
Sbjct: 908 PFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQ 967
Query: 325 TAITVH-YLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDN------IRLRSSP 377
+ V + P +V+ + C + TV W +D + L+
Sbjct: 968 LEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQN 1027
Query: 378 SFSSLHYQDA-----GNYVCETALQEVEGLKKRESLTLIVEGKPQI-----KMTKKTDPS 427
SLH + A G Y C + + G +R+ L V P++ +T T
Sbjct: 1028 QGQSLHVERAQAAHTGRYSC--VAENLAGRAERK-FELSVLVPPELIGDLDPLTNITAAL 1084
Query: 428 GLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTL-TCT 486
T++C G P PAI+W ++ E++ + G + K+ + E++ L +C
Sbjct: 1085 HSPLTLLCEAMGIPPPAIRW--FRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCL 1142
Query: 487 AENQLERTVNSLNVSAISIP--EHDEADEI 514
A N+ + +V + P E+++ +E+
Sbjct: 1143 ASNEAGEARRNFSVEVLVPPSIENEDLEEV 1172
Score = 43.5 bits (101), Expect = 5e-04
Identities = 44/213 (20%), Positives = 78/213 (36%), Gaps = 21/213 (9%)
Query: 309 GDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTRQIGDA-LPVSCTISASRNATVVWM 367
G Y CS + + + P V R + + + + C S T+ W
Sbjct: 2641 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQ 2700
Query: 368 KDNIRLRSSPSFSSL----------HYQDAGNYVCETALQEVEGLKKRESLT----LIVE 413
K+ + + + S L +DAGNY+C + K + +I
Sbjct: 2701 KEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIEN 2760
Query: 414 GKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKI 473
G P + T+ G + C G P+P I W G + + + +G K
Sbjct: 2761 GLPDLSTTE-----GSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKN 2815
Query: 474 IISPEENVTLTCTAENQLERTVNSLNVSAISIP 506
+ + T TCTAEN + R ++++ + +P
Sbjct: 2816 LEGQDAG-TYTCTAENAVGRARRRVHLTILVLP 2847
Score = 40.4 bits (93), Expect = 0.005
Identities = 62/295 (21%), Positives = 105/295 (35%), Gaps = 37/295 (12%)
Query: 266 ITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTL--------TDVRRNATGDYKCSLID 317
+TL C G PPP + + G+ +TY L T + +G Y C L
Sbjct: 1088 LTLLCEAMGIPPPA--IRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSC-LAS 1144
Query: 318 KKSMIASTAITVHYL---DLSLNPSGEVTRQI-GDALPVSCTISASRNATVVWMKDNIRL 373
++ A +V L + EV + + G + C ++ + W KD L
Sbjct: 1145 NEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPL 1204
Query: 374 RSSPSFS-----------SLHYQDAGNYVCETALQEVEGLKKRESLTL----IVEGKPQI 418
+ + AG+Y C A E K + L I+ G
Sbjct: 1205 ARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDS 1264
Query: 419 KMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPE 478
+ T ++IC FP P I W G+ + + G + +I+ + +
Sbjct: 1265 ADEEVTVTVNNPISLICEALAFPSPNITW--MKDGAPFEASRNIQLLPGTHGLQILNAQK 1322
Query: 479 ENV-TLTCTAENQLERTVNSLNVSAISIPEHDEADEISD----ENREKVNDQAKL 528
E+ TC N+L V + +V + P + D +++ E + KVN L
Sbjct: 1323 EDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKTKVNSTLTL 1377
Score = 40.0 bits (92), Expect = 0.006
Identities = 85/422 (20%), Positives = 148/422 (35%), Gaps = 80/422 (18%)
Query: 92 LSENYTLSISNARISDEKRFVCMLVT----EDNVFEA-----PTIVKVFKQPSKPEIVSK 142
L E L I ++SD R++C+ +D F P KV + EI+S+
Sbjct: 1407 LGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSR 1466
Query: 143 --------ALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDP 194
+ E + ++ P ++TWYR + PL D
Sbjct: 1467 EEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQ---PLSAG---------DE 1514
Query: 195 VTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFD---IYYPTEQVTI 251
V+ L L+ +A+ ++C + G+ +H E V I TE++
Sbjct: 1515 VSVLQG-GRVLQIPLVRAENAGRYSCKAS--NEVGEDWLHYELLVLTPPVILGDTEELVE 1571
Query: 252 QVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFY--LPGQP----EGIRSSNTYTLTDVRR 305
+V + ++L+C GNP P LP P + + ++
Sbjct: 1572 EV-----TVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV 1626
Query: 306 NATGDYKCSLIDKKSMIASTAITVHYLDLSLNPS------GEVTRQIGDALPVSCTISAS 359
Y C ++ A +A + L + + P +VT + ++ + C + A
Sbjct: 1627 ADAASYMCVAENQ----AGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAH 1682
Query: 360 RNATVVWMKDNIRLRSSPSFSSL-----------HYQDAGNYVCETALQEVEGLKKRESL 408
N V W KD+ L L D+G Y CE AL +K L
Sbjct: 1683 PNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCE-ALNAAGRDQKLVQL 1741
Query: 409 TLIV--------EGKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTE 460
+++V G + + D + LS C + P+P + W G V+ Q
Sbjct: 1742 SVLVPPAFRQAPRGPQDAVLVRVGDKAVLS----CETDALPEPTVTWYKDGQPLVLAQRT 1797
Query: 461 ES 462
++
Sbjct: 1798 QA 1799
Score = 39.3 bits (90), Expect = 0.010
Identities = 51/236 (21%), Positives = 96/236 (40%), Gaps = 44/236 (18%)
Query: 248 QVTIQVLPPKN--------AIKEGDNITLKCLGNGNPPPEEFLFYLPGQP----EGIRSS 295
+V ++VL P N A+ E ++TL+CL +G PPP + ++ QP G+ S
Sbjct: 595 EVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPP-DVSWFKGHQPVSSWMGVTVS 653
Query: 296 ---NTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYL------DLSLNPSGEVTRQI 346
+ + + G Y+C S +A + + L ++L PS +
Sbjct: 654 VDGRVLRIEQAQLSDAGSYRC----VASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLV 709
Query: 347 GDALPVSCTISASRNATVVWMKDN--IRLRSSP-----------SFSSLHYQDAGNYVCE 393
+ ++C + + + T++W+KD + +P + +S D+G Y C
Sbjct: 710 NTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSC- 768
Query: 394 TALQEVEGLKKRESLTLIVEGKPQI--KMTKKTDPSGLSKTIICHVEGFPKPAIQW 447
A+ V + R+ + L V P I + + + S + C P P + W
Sbjct: 769 VAVSAVG--EDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSW 822
Score = 36.6 bits (83), Expect = 0.065
Identities = 60/291 (20%), Positives = 110/291 (37%), Gaps = 40/291 (13%)
Query: 94 ENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPS--KPEIVSKALFLETEQL 151
+ L I+ + + DE R+ C+ + ++V P+ + +E +
Sbjct: 179 DGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLV 238
Query: 152 KKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTST-LEYKTT 210
+ L + P NITW+++G +L P VV YT L+
Sbjct: 239 QLLCEA---RGVPTPNITWFKDGALL-PTSTKVV-------------YTRGGRQLQLGRA 281
Query: 211 KADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKC 270
++ +TC + + +K D+Y P P G + L+C
Sbjct: 282 QSSDAGVYTCKASNAVGAAEKATR-----LDVYVPPTIEGAGGRPYVVKAVAGRPVALEC 336
Query: 271 LGNGNPPPEEFLFYLPGQPEGIRSSNTYTL-TD---VRRNATGDYKCSLID-KKSMIAST 325
+ G+P P ++ G P + SN L TD +R + G+ L S A
Sbjct: 337 VARGHPSPT-LSWHHEGLP--VAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGE 393
Query: 326 AITVHYLDLSLNPS-------GEVTRQIGDALPVSCTISASRNATVVWMKD 369
A+ + +++ + P G+VT +G L + C S S T+ W+++
Sbjct: 394 AVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQN 444
Score = 36.2 bits (82), Expect = 0.086
Identities = 68/327 (20%), Positives = 112/327 (34%), Gaps = 70/327 (21%)
Query: 156 DCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQ 215
DC D P ++ W ++G L ++M P + Y +L K +A
Sbjct: 1956 DC-EADGQPPPDVAWLKDGSPLG-----------QDMGPHLRFYLDGGSLVLKGLRASDA 2003
Query: 216 MPFTCSVTYYGPSGQKT-IHSEQAVFDIYYPTEQVTIQVLPPKN-----------AIKEG 263
+TC + P+G+ +H T+ VL P + G
Sbjct: 2004 GAYTCVA--HNPAGEDARLH---------------TVNVLVPPTIKQGADGSGTLVSRPG 2046
Query: 264 DNITLKCLGNGNPPPEEFLFYLPGQPEGIR-------SSNTYTLTDVRRNATGDYKCSLI 316
+ +T+ C G+PP + G P + S +T ++ V+ G + C
Sbjct: 2047 ELVTMVCPVRGSPPIH-VSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAA 2105
Query: 317 DKKSMIASTAITVHYLDLSLNP---SGEVTRQIGDALPVSCTISASRNATVVWMKDNIRL 373
+ + L P +V G + + C V WMKD L
Sbjct: 2106 SPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPL 2165
Query: 374 RS-------SPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDP 426
S S ++ D+G Y C + E R L V P I+ + + P
Sbjct: 2166 LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEA---RRHFQLTVMEPPHIEDSGQ--P 2220
Query: 427 SGLSKT------IICHVEGFPKPAIQW 447
+ LS T ++C +G P+P I W
Sbjct: 2221 TELSLTPGAPMELLCDAQGTPQPNITW 2247
Score = 35.8 bits (81), Expect = 0.11
Identities = 70/307 (22%), Positives = 106/307 (34%), Gaps = 55/307 (17%)
Query: 164 PDGNITWYRNGKVLHPLEG---AVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTC 220
P NITW+++G+ L LE A ++ ++ T L + K+ + +Q P
Sbjct: 2241 PQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAP--- 2297
Query: 221 SVTYYGPSGQKTI---HSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPP 277
GP G + + Q V + +++ P D I L+ + P
Sbjct: 2298 -PNIVGPRGPRFVVGLAPGQLVL-------ECSVEAEPAPKITWHRDGIVLQEDAHTQFP 2349
Query: 278 PEEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLN 337
E +L Q S Y+ T RNA G S + + +H + +
Sbjct: 2350 --ERGRFLQLQALSTADSGDYSCT--ARNAAG----------STSVAFRVEIHTVPTIRS 2395
Query: 338 PSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRL-RSSPSFSSLH----------YQD 386
V + + C V W KD + L SP F L QD
Sbjct: 2396 GPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQD 2455
Query: 387 AGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDPSGLSKT------IICHVEGF 440
AG+Y+C L R+ L V P I PS L+ T + C G
Sbjct: 2456 AGHYLC---LASNSAGSDRQGRDLRVLEPPAI----APSPSNLTLTAHTPALLPCEASGS 2508
Query: 441 PKPAIQW 447
PKP + W
Sbjct: 2509 PKPLVVW 2515
Score = 35.4 bits (80), Expect = 0.15
Identities = 47/226 (20%), Positives = 85/226 (37%), Gaps = 47/226 (20%)
Query: 260 IKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYT-------LTDVRRNATGDYK 312
+ +G L C G+P P+ ++ G+P ++ + + ++ G Y
Sbjct: 1175 VLDGQTAHLMCNVTGHPQPK-LTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYS 1233
Query: 313 CSLIDKKSMIASTAI---TVHY-LDLSLNPS----------GEVTRQIGDALPVSCTISA 358
C IA+ A+ T H+ L + L P+ EVT + + + + C A
Sbjct: 1234 C--------IAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALA 1285
Query: 359 SRNATVVWMKDNIRLRSSPSFSSL-----------HYQDAGNYVCETALQEVEGLKKRES 407
+ + WMKD +S + L +DAG Y C + E +K
Sbjct: 1286 FPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHV 1345
Query: 408 LTL----IVEGKPQIKMTKKTDPSGLSKTIICHVEGF--PKPAIQW 447
L I + P ++ K + ++ T+ E + P P I+W
Sbjct: 1346 EVLIPPSISKDDPLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRW 1391
Score = 33.9 bits (76), Expect = 0.42
Identities = 82/383 (21%), Positives = 132/383 (34%), Gaps = 51/383 (13%)
Query: 94 ENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPS--KPEIVSKALFLETEQL 151
EN + + R+ D + C+ + E V+V P+ P + L QL
Sbjct: 2258 ENNSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQL 2317
Query: 152 KKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTK 211
+ +C S ++ P ITW+R+G VL + D TQ L+ +
Sbjct: 2318 --VLEC-SVEAEPAPKITWHRDGIVL-------------QEDAHTQFPERGRFLQLQALS 2361
Query: 212 ADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCL 271
++C+ + S F + T TI+ PP + L C
Sbjct: 2362 TADSGDYSCTA-------RNAAGSTSVAFRVEIHTVP-TIRSGPPAVNVSVNQTALLPCQ 2413
Query: 272 GNGNPPP-----EEFLFYLPGQPE-GIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIAST 325
+G P P ++ + P P I + + V G Y C L +
Sbjct: 2414 ADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLC-LASNSAGSDRQ 2472
Query: 326 AITVHYLD---LSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRL--------- 373
+ L+ ++ +PS AL + C S S VVW KD +L
Sbjct: 2473 GRDLRVLEPPAIAPSPSNLTLTAHTPAL-LPCEASGSPKPLVVWWKDGQKLDFRLQQGAY 2531
Query: 374 RSSPSFSSLHY----QDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDPSGL 429
R PS + L QD+ + C + EV + +T+ V T T
Sbjct: 2532 RLLPSNALLLTAPGPQDSAQFECVVS-NEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMA 2590
Query: 430 SKTIICHVEGFPKPAIQWTITGS 452
+ CH G P P + W+ G+
Sbjct: 2591 PVVLTCHSTGIPAPTVSWSKAGA 2613
Score = 33.5 bits (75), Expect = 0.55
Identities = 94/449 (20%), Positives = 158/449 (35%), Gaps = 83/449 (18%)
Query: 90 LNLSENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEI---VSKALFL 146
L+ + +Y+ +NA K F + +V APTI+ + + E+ V+ + L
Sbjct: 1226 LSSAGHYSCIAANAVGEKTKHF------QLSVLLAPTILGGAEDSADEEVTVTVNNPISL 1279
Query: 147 ETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLE 206
E L ++P NITW ++G P E + I QL T L+
Sbjct: 1280 ICEAL----------AFPSPNITWMKDGA---PFEASRNI----------QLLPGTHGLQ 1316
Query: 207 YKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNI 266
+ + +TC VT K H E + + +V + K +
Sbjct: 1317 ILNAQKEDAGQYTCVVTNELGEAVKNYHVE-VLIPPSISKDDPLAEVGVKEVKTKVNSTL 1375
Query: 267 TLKCLGNGNPPPEEFLFYLPGQP-------EGIRSSNTYTLTDVRRNATGDYKC------ 313
TL+C PPP +Y GQP + + + + + +G Y C
Sbjct: 1376 TLECESWAVPPP-TIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVA 1434
Query: 314 --------SLIDKKSM---IASTAITVHYLDLSLNPSGEVT--RQIGDALP--VSCTISA 358
LI M + + L G VT R+I + P + C +A
Sbjct: 1435 GEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNA 1494
Query: 359 SRNATVVWMKDNIRLRSSPSFSSL-----------HYQDAGNYVCETALQEVEGLKKRES 407
+ W +++ L + S L ++AG Y C+ + + E E
Sbjct: 1495 IPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYEL 1554
Query: 408 LTL---IVEGKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITG---SGSVINQTEE 461
L L ++ G + + + T + + ++ C G P P I W G S S Q E
Sbjct: 1555 LVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLE 1614
Query: 462 SPYINGRYYSKIIISPEENVTLTCTAENQ 490
+G+ + + C AENQ
Sbjct: 1615 ----DGQVLQVSTAEVADAASYMCVAENQ 1639
>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
sapiens]
Length = 848
Score = 58.5 bits (140), Expect = 2e-08
Identities = 59/310 (19%), Positives = 125/310 (40%), Gaps = 37/310 (11%)
Query: 233 IHSEQAVFDIYYPTEQVTIQV--LPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPG--- 287
+ ++ ++ +++ V++QV +P + I G++ C G+ ++ ++ P
Sbjct: 2 LQTKDLIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEK 61
Query: 288 -QPEGIR--------SSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNP 338
P R SS+T T+ + + G YKC + + + + V +
Sbjct: 62 LTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFK 121
Query: 339 SGEVTRQI--GDALPVSCTISASRNATVVW--------MKDNIRL----RSSPSFSSLHY 384
+ ++ G+ + C + +S T++W +K ++R + +
Sbjct: 122 NAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKK 181
Query: 385 QDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIK----MTKKTDPSGLSKTIICHVEGF 440
D G Y CE + G + + +IV P I+ + T G S T++C EGF
Sbjct: 182 TDEGTYRCEGRIL-ARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGF 240
Query: 441 PKPAIQWTITGSGSVINQTEESPYINGRYYSKIII---SPEENVTLTCTAENQLERTVNS 497
P+P + WT G + + ++ YI S++ I + C AEN+ +
Sbjct: 241 PEPTMSWTKDGE-QIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDAT 299
Query: 498 LNVSAISIPE 507
+++ + P+
Sbjct: 300 IHLKVFAKPK 309
Score = 46.6 bits (109), Expect = 6e-05
Identities = 99/459 (21%), Positives = 169/459 (36%), Gaps = 59/459 (12%)
Query: 91 NLSENYTLSISNARISDEKRFVCMLVTED-NVFEAPTIVKVFKQPSKPEIVSKALFLETE 149
N + TL+I NA I D + C++ ED + EA VK+F++ + F E E
Sbjct: 74 NDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGE 133
Query: 150 QLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKT 209
+ D +S S P I W G+ +I KK+ V + + L+ +
Sbjct: 134 DAVIVCDVVS--SLPP-TIIWKHKGRD---------VILKKD---VRFIVLSNNYLQIRG 178
Query: 210 TKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKE-GDNITL 268
K + + C G+ Q + ++ PT Q ++ NA G ++TL
Sbjct: 179 IKKTDEGTYRCEGRILA-RGEINFKDIQVIVNVP-PTIQARQNIV---NATANLGQSVTL 233
Query: 269 KCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTD---------VRRNATGDYKCSLIDKK 319
C G P P Q E Y +D V +N +Y C +K
Sbjct: 234 VCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKA 293
Query: 320 S---------MIASTAITVHYLDLSLNPSGEVT---RQIGDALPVSCTISASRNATV--- 364
+ A IT ++ +VT GD +P +++RN +
Sbjct: 294 GEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEK 353
Query: 365 -----VWMKDNIRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIK 419
+ ++ + R+ SS + S+ Y DAG Y+C TA + + +S+ L V+ P+++
Sbjct: 354 TLDGHMVVRSHARV-SSLTLKSIQYTDAGEYIC-TASNTIG--QDSQSMYLEVQYAPKLQ 409
Query: 420 MTKKTDP-SGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPE 478
G I C V +P I W G + N S + ++P+
Sbjct: 410 GPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPD 469
Query: 479 EN---VTLTCTAENQLERTVNSLNVSAISIPEHDEADEI 514
CTA N++ + + P D++
Sbjct: 470 SENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQV 508
>gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo
sapiens]
Length = 858
Score = 58.5 bits (140), Expect = 2e-08
Identities = 59/310 (19%), Positives = 125/310 (40%), Gaps = 37/310 (11%)
Query: 233 IHSEQAVFDIYYPTEQVTIQV--LPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPG--- 287
+ ++ ++ +++ V++QV +P + I G++ C G+ ++ ++ P
Sbjct: 2 LQTKDLIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEK 61
Query: 288 -QPEGIR--------SSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNP 338
P R SS+T T+ + + G YKC + + + + V +
Sbjct: 62 LTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFK 121
Query: 339 SGEVTRQI--GDALPVSCTISASRNATVVW--------MKDNIRL----RSSPSFSSLHY 384
+ ++ G+ + C + +S T++W +K ++R + +
Sbjct: 122 NAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKK 181
Query: 385 QDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIK----MTKKTDPSGLSKTIICHVEGF 440
D G Y CE + G + + +IV P I+ + T G S T++C EGF
Sbjct: 182 TDEGTYRCEGRIL-ARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGF 240
Query: 441 PKPAIQWTITGSGSVINQTEESPYINGRYYSKIII---SPEENVTLTCTAENQLERTVNS 497
P+P + WT G + + ++ YI S++ I + C AEN+ +
Sbjct: 241 PEPTMSWTKDGE-QIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDAT 299
Query: 498 LNVSAISIPE 507
+++ + P+
Sbjct: 300 IHLKVFAKPK 309
Score = 43.5 bits (101), Expect = 5e-04
Identities = 100/469 (21%), Positives = 169/469 (36%), Gaps = 69/469 (14%)
Query: 91 NLSENYTLSISNARISDEKRFVCMLVTED-NVFEAPTIVKVFKQPSKPEIVSKALFLETE 149
N + TL+I NA I D + C++ ED + EA VK+F++ + F E E
Sbjct: 74 NDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGE 133
Query: 150 QLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKT 209
+ D +S S P I W G+ +I KK+ V + + L+ +
Sbjct: 134 DAVIVCDVVS--SLPP-TIIWKHKGR---------DVILKKD---VRFIVLSNNYLQIRG 178
Query: 210 TKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKE-GDNITL 268
K + + C G+ Q + ++ PT Q ++ NA G ++TL
Sbjct: 179 IKKTDEGTYRCEGRILA-RGEINFKDIQVIVNV-PPTIQARQNIV---NATANLGQSVTL 233
Query: 269 KCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTD---------VRRNATGDYKCSLIDKK 319
C G P P Q E Y +D V +N +Y C +K
Sbjct: 234 VCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKA 293
Query: 320 ---------SMIASTAITVHYLDLSLNPSGEVT---RQIGDALPVSCTISASRNAT---- 363
+ A IT ++ +VT GD +P +++RN +
Sbjct: 294 GEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEK 353
Query: 364 VVW--------------MKDNIRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLT 409
W ++ + R+ SS + S+ Y DAG Y+C TA + + +S+
Sbjct: 354 ASWTRPEKQETLDGHMVVRSHARV-SSLTLKSIQYTDAGEYIC-TASNTIG--QDSQSMY 409
Query: 410 LIVEGKPQIKMTKKTDP-SGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGR 468
L V+ P+++ G I C V +P I W G + N
Sbjct: 410 LEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTP 469
Query: 469 YYSKIIISPEEN---VTLTCTAENQLERTVNSLNVSAISIPEHDEADEI 514
S + ++P+ CTA N++ + + P D++
Sbjct: 470 SASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQV 518
>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
sapiens]
Length = 761
Score = 58.5 bits (140), Expect = 2e-08
Identities = 59/310 (19%), Positives = 125/310 (40%), Gaps = 37/310 (11%)
Query: 233 IHSEQAVFDIYYPTEQVTIQV--LPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPG--- 287
+ ++ ++ +++ V++QV +P + I G++ C G+ ++ ++ P
Sbjct: 2 LQTKDLIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEK 61
Query: 288 -QPEGIR--------SSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNP 338
P R SS+T T+ + + G YKC + + + + V +
Sbjct: 62 LTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFK 121
Query: 339 SGEVTRQI--GDALPVSCTISASRNATVVW--------MKDNIRL----RSSPSFSSLHY 384
+ ++ G+ + C + +S T++W +K ++R + +
Sbjct: 122 NAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKK 181
Query: 385 QDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIK----MTKKTDPSGLSKTIICHVEGF 440
D G Y CE + G + + +IV P I+ + T G S T++C EGF
Sbjct: 182 TDEGTYRCEGRIL-ARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGF 240
Query: 441 PKPAIQWTITGSGSVINQTEESPYINGRYYSKIII---SPEENVTLTCTAENQLERTVNS 497
P+P + WT G + + ++ YI S++ I + C AEN+ +
Sbjct: 241 PEPTMSWTKDGE-QIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDAT 299
Query: 498 LNVSAISIPE 507
+++ + P+
Sbjct: 300 IHLKVFAKPK 309
Score = 46.6 bits (109), Expect = 6e-05
Identities = 99/459 (21%), Positives = 169/459 (36%), Gaps = 59/459 (12%)
Query: 91 NLSENYTLSISNARISDEKRFVCMLVTED-NVFEAPTIVKVFKQPSKPEIVSKALFLETE 149
N + TL+I NA I D + C++ ED + EA VK+F++ + F E E
Sbjct: 74 NDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGE 133
Query: 150 QLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKT 209
+ D +S S P I W G+ +I KK+ V + + L+ +
Sbjct: 134 DAVIVCDVVS--SLPP-TIIWKHKGRD---------VILKKD---VRFIVLSNNYLQIRG 178
Query: 210 TKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKE-GDNITL 268
K + + C G+ Q + ++ PT Q ++ NA G ++TL
Sbjct: 179 IKKTDEGTYRCEGRILA-RGEINFKDIQVIVNVP-PTIQARQNIV---NATANLGQSVTL 233
Query: 269 KCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTD---------VRRNATGDYKCSLIDKK 319
C G P P Q E Y +D V +N +Y C +K
Sbjct: 234 VCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKA 293
Query: 320 S---------MIASTAITVHYLDLSLNPSGEVT---RQIGDALPVSCTISASRNATV--- 364
+ A IT ++ +VT GD +P +++RN +
Sbjct: 294 GEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEK 353
Query: 365 -----VWMKDNIRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIK 419
+ ++ + R+ SS + S+ Y DAG Y+C TA + + +S+ L V+ P+++
Sbjct: 354 TLDGHMVVRSHARV-SSLTLKSIQYTDAGEYIC-TASNTIG--QDSQSMYLEVQYAPKLQ 409
Query: 420 MTKKTDP-SGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPE 478
G I C V +P I W G + N S + ++P+
Sbjct: 410 GPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPD 469
Query: 479 EN---VTLTCTAENQLERTVNSLNVSAISIPEHDEADEI 514
CTA N++ + + P D++
Sbjct: 470 SENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQV 508
>gi|18201909 vascular cell adhesion molecule 1 isoform b precursor
[Homo sapiens]
Length = 647
Score = 57.8 bits (138), Expect = 3e-08
Identities = 94/438 (21%), Positives = 158/438 (36%), Gaps = 60/438 (13%)
Query: 97 TLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGD 156
TL+++ +E ++C E E V+++ P PEI + +
Sbjct: 79 TLTMNPVSFGNEHSYLCTATCESRKLEKGIQVEIYSFPKDPEIHLSGPLEAGKPITV--K 136
Query: 157 CISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKA--DI 214
C D YP + + L+G ++ ++ ++ + T +LE T DI
Sbjct: 137 CSVADVYPFDRLE-------IDLLKGDHLMKSQEFLEDADRKSLETKSLEVTFTPVIEDI 189
Query: 215 QMPFTCSVTYYGPSGQKTIHSEQAVFDIY-YPTEQVTIQVLPPKNAIKEGDNITLKCLGN 273
C + QAV ++ Y + + T+ + P ++EG ++T+ C
Sbjct: 190 GKVLVCRAKLHIDEMDSVPTVRQAVKELQVYISPKNTVISVNPSTKLQEGGSVTMTCSSE 249
Query: 274 GNPPPEEFLFYL--PGQPEGIRSSNTYTLTDVRRNATGDYKC---SLIDKKSMIASTAIT 328
G P PE F G + + + T TL +R +G Y C +LI K +
Sbjct: 250 GLPAPEIFWSKKLDNGNLQHLSGNATLTLIAMRMEDSGIYVCEGVNLIGKNRKEVELIVQ 309
Query: 329 VHYLDLSLNPSGEVTRQIGDALPVSC-----------TISASRNATVVWMKDNIRLRSSP 377
D + SG + G ++ VSC I + T++ +NI
Sbjct: 310 AFPRDPEIEMSGGLVN--GSSVTVSCKVPSVYPLDRLEIELLKGETIL---ENIEFLEDT 364
Query: 378 SFSSLH-----------YQDAGN-YVCETAL----QEVEGLKKRESLTLIVEGKPQIKMT 421
SL +D G VC+ L E E +++ + TL V P+ T
Sbjct: 365 DMKSLENKSLEMTFIPTIEDTGKALVCQAKLHIDDMEFEPKQRQSTQTLYVNVAPR-DTT 423
Query: 422 KKTDPS-----GLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIIS 476
PS G S + C +GFP P I W+ + E P + I
Sbjct: 424 VLVSPSSILEEGSSVNMTCLSQGFPAPKILWS-----RQLPNGELQPLSENATLTLISTK 478
Query: 477 PEENVTLTCTAENQLERT 494
E++ C NQ R+
Sbjct: 479 MEDSGVYLCEGINQAGRS 496
>gi|221316762 neurotrimin isoform 4 [Homo sapiens]
Length = 316
Score = 57.0 bits (136), Expect = 5e-08
Identities = 51/221 (23%), Positives = 91/221 (41%), Gaps = 29/221 (13%)
Query: 192 MDPVTQLYTMTST---LEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQ 248
+DP L + T T +E + + P+TCSV +H + + +
Sbjct: 84 LDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVH---LIVQVSPKIVE 140
Query: 249 VTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTY-TLTDVRRNA 307
++ + +I EG+NI+L C+ G P P ++ + G S + Y + + R
Sbjct: 141 ISSDI-----SINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGITREQ 195
Query: 308 TGDYKCSLIDKKS--MIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVV 365
+GDY+CS + + ++ +TV+Y G +G + C SA +A
Sbjct: 196 SGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGV-PVGQKGTLQCEASAVPSAEFQ 254
Query: 366 WMKDN---------IRLRSSPSFSSLHY-----QDAGNYVC 392
W KD+ +++ + P S L + D GNY C
Sbjct: 255 WYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTC 295
>gi|221316757 neurotrimin isoform 3 [Homo sapiens]
Length = 355
Score = 57.0 bits (136), Expect = 5e-08
Identities = 51/221 (23%), Positives = 91/221 (41%), Gaps = 29/221 (13%)
Query: 192 MDPVTQLYTMTST---LEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQ 248
+DP L + T T +E + + P+TCSV +H + + +
Sbjct: 84 LDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVH---LIVQVSPKIVE 140
Query: 249 VTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTY-TLTDVRRNA 307
++ + +I EG+NI+L C+ G P P ++ + G S + Y + + R
Sbjct: 141 ISSDI-----SINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGITREQ 195
Query: 308 TGDYKCSLIDKKS--MIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVV 365
+GDY+CS + + ++ +TV+Y G +G + C SA +A
Sbjct: 196 SGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGV-PVGQKGTLQCEASAVPSAEFQ 254
Query: 366 WMKDN---------IRLRSSPSFSSLHY-----QDAGNYVC 392
W KD+ +++ + P S L + D GNY C
Sbjct: 255 WYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTC 295
>gi|115298665 neurotrimin isoform 2 [Homo sapiens]
Length = 344
Score = 57.0 bits (136), Expect = 5e-08
Identities = 51/221 (23%), Positives = 91/221 (41%), Gaps = 29/221 (13%)
Query: 192 MDPVTQLYTMTST---LEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQ 248
+DP L + T T +E + + P+TCSV +H + + +
Sbjct: 84 LDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVH---LIVQVSPKIVE 140
Query: 249 VTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTY-TLTDVRRNA 307
++ + +I EG+NI+L C+ G P P ++ + G S + Y + + R
Sbjct: 141 ISSDI-----SINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGITREQ 195
Query: 308 TGDYKCSLIDKKS--MIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVV 365
+GDY+CS + + ++ +TV+Y G +G + C SA +A
Sbjct: 196 SGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGV-PVGQKGTLQCEASAVPSAEFQ 254
Query: 366 WMKDN---------IRLRSSPSFSSLHY-----QDAGNYVC 392
W KD+ +++ + P S L + D GNY C
Sbjct: 255 WYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTC 295
>gi|7705413 neurotrimin isoform 1 [Homo sapiens]
Length = 344
Score = 57.0 bits (136), Expect = 5e-08
Identities = 51/221 (23%), Positives = 91/221 (41%), Gaps = 29/221 (13%)
Query: 192 MDPVTQLYTMTST---LEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQ 248
+DP L + T T +E + + P+TCSV +H + + +
Sbjct: 84 LDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVH---LIVQVSPKIVE 140
Query: 249 VTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTY-TLTDVRRNA 307
++ + +I EG+NI+L C+ G P P ++ + G S + Y + + R
Sbjct: 141 ISSDI-----SINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGITREQ 195
Query: 308 TGDYKCSLIDKKS--MIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVV 365
+GDY+CS + + ++ +TV+Y G +G + C SA +A
Sbjct: 196 SGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGV-PVGQKGTLQCEASAVPSAEFQ 254
Query: 366 WMKDN---------IRLRSSPSFSSLHY-----QDAGNYVC 392
W KD+ +++ + P S L + D GNY C
Sbjct: 255 WYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTC 295
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,968,030
Number of Sequences: 37866
Number of extensions: 1066270
Number of successful extensions: 3893
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 242
Number of HSP's that attempted gapping in prelim test: 2439
Number of HSP's gapped (non-prelim): 1285
length of query: 583
length of database: 18,247,518
effective HSP length: 108
effective length of query: 475
effective length of database: 14,157,990
effective search space: 6725045250
effective search space used: 6725045250
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.