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Search of human proteins with 66346706
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66346706 neuronal growth regulator 1 [Homo sapiens]
(354 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66346706 neuronal growth regulator 1 [Homo sapiens] 728 0.0
gi|45594240 limbic system-associated membrane protein [Homo sapi... 364 e-101
gi|7705413 neurotrimin isoform 1 [Homo sapiens] 322 4e-88
gi|115298665 neurotrimin isoform 2 [Homo sapiens] 320 1e-87
gi|4505505 opioid binding protein/cell adhesion molecule-like is... 320 2e-87
gi|221316762 neurotrimin isoform 4 [Homo sapiens] 318 4e-87
gi|221316757 neurotrimin isoform 3 [Homo sapiens] 318 4e-87
gi|59939900 opioid binding protein/cell adhesion molecule-like i... 316 2e-86
gi|157819143 IgLON family member 5 [Homo sapiens] 259 3e-69
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 105 5e-23
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 105 5e-23
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ... 105 5e-23
gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens] 99 4e-21
gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens] 99 4e-21
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 97 2e-20
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap... 97 2e-20
gi|118572606 hemicentin 1 [Homo sapiens] 96 5e-20
gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 96 5e-20
gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo sap... 94 2e-19
gi|7662320 leucine-rich repeats and immunoglobulin-like domains ... 89 6e-18
gi|7657359 contactin 5 isoform long [Homo sapiens] 89 8e-18
gi|28373129 contactin 5 isoform short [Homo sapiens] 89 8e-18
gi|109150416 peroxidasin [Homo sapiens] 87 2e-17
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens] 87 3e-17
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 86 5e-17
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 86 5e-17
gi|142976733 surface glycoprotein, Ig superfamily member [Homo s... 86 5e-17
gi|139948432 adlican [Homo sapiens] 83 3e-16
gi|40255157 leucine-rich repeats and immunoglobulin-like domains... 82 7e-16
gi|209862903 leucine-rich repeats and immunoglobulin-like domain... 82 7e-16
>gi|66346706 neuronal growth regulator 1 [Homo sapiens]
Length = 354
Score = 728 bits (1880), Expect = 0.0
Identities = 354/354 (100%), Positives = 354/354 (100%)
Query: 1 MDMMLLVQGACCSNQWLAAVLLSLCCLLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRC 60
MDMMLLVQGACCSNQWLAAVLLSLCCLLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRC
Sbjct: 1 MDMMLLVQGACCSNQWLAAVLLSLCCLLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRC 60
Query: 61 YLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSV 120
YLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSV
Sbjct: 61 YLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSV 120
Query: 121 QTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAK 180
QTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAK
Sbjct: 121 QTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAK 180
Query: 181 PFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRS 240
PFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRS
Sbjct: 181 PFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRS 240
Query: 241 GLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAA 300
GLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAA
Sbjct: 241 GLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAA 300
Query: 301 NKLGTTNASLPLNPPSTAQYGITGSADVLFSCWYLVLTLSSFTSIFYLKNAILQ 354
NKLGTTNASLPLNPPSTAQYGITGSADVLFSCWYLVLTLSSFTSIFYLKNAILQ
Sbjct: 301 NKLGTTNASLPLNPPSTAQYGITGSADVLFSCWYLVLTLSSFTSIFYLKNAILQ 354
>gi|45594240 limbic system-associated membrane protein [Homo
sapiens]
Length = 338
Score = 364 bits (935), Expect = e-101
Identities = 185/324 (57%), Positives = 236/324 (72%), Gaps = 5/324 (1%)
Query: 17 LAAVLLSLCCLLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRSS 76
L VLL L CLLP+ LP +SVDF DN+ VR+GDTA+LRC +ED SK AWLNRS
Sbjct: 12 LPLVLLRLLCLLPTGLPV-RSVDFN-RGTDNITVRQGDTAILRCVVEDKNSKVAWLNRSG 69
Query: 77 IIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQ 136
IIFAG DKWS+DPRV + + +YSL+IQ VDV D+G YTCSVQTQH P+T QV+L VQ
Sbjct: 70 IIFAGHDKWSLDPRVELEKRHSLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQ 129
Query: 137 VPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFE-NGQYLDIYGITR 195
VPPKI +IS+D+TVNEG+NVTL C+A G+PEP I+WRH++P+ + FE +YL+I GITR
Sbjct: 130 VPPKISNISSDVTVNEGSNVTLVCMANGRPEPVITWRHLTPTGREFEGEEEYLEILGITR 189
Query: 196 DQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAF 255
+Q+G+YEC A N+VS DV++VKV VN+ PTI E KS T GR ++CE + VP P F
Sbjct: 190 EQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNEATTGRQASLKCEASAVPAPDF 249
Query: 256 EWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPP 315
EWY+ + ++ N G+ I++ +S LTVTNVT+EH+GNYTCVAANKLG TNASL L P
Sbjct: 250 EWYRDDTRI-NSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNASLVLFRP 308
Query: 316 STAQYGITGSADVLFSCWYLVLTL 339
+ + GI GS + W L +L
Sbjct: 309 GSVR-GINGSISLAVPLWLLAASL 331
>gi|7705413 neurotrimin isoform 1 [Homo sapiens]
Length = 344
Score = 322 bits (824), Expect = 4e-88
Identities = 158/323 (48%), Positives = 223/323 (69%), Gaps = 3/323 (0%)
Query: 17 LAAVLLSLCCLLPSCLPAGQS-VDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRS 75
L V L L L+P+ +P FP A+DN+ VR+G++A LRC +++ ++ AWLNRS
Sbjct: 14 LVVVSLRLLFLVPTGVPVRSGDATFP-KAMDNVTVRQGESATLRCTIDNRVTRVAWLNRS 72
Query: 76 SIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTV 135
+I++AG DKW +DPRV + + + YS++IQNVDV D+GPYTCSVQT + P+T +VHL V
Sbjct: 73 TILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV 132
Query: 136 QVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPF-ENGQYLDIYGIT 194
QV PKI +IS+D+++NEG N++LTC+ATG+PEP+++WRHISP A F +YL+I GIT
Sbjct: 133 QVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGIT 192
Query: 195 RDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPA 254
R+Q+G+YECSA NDV+ P VR+VKV VN+ P I E K V G+ G ++CE + VP
Sbjct: 193 REQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAE 252
Query: 255 FEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNP 314
F+WYK +K+L G++G+ ++N S L NV++ +GNYTCVA+NKLG TNAS+ L
Sbjct: 253 FQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFG 312
Query: 315 PSTAQYGITGSADVLFSCWYLVL 337
P G++ W L L
Sbjct: 313 PGAVSEVSNGTSRRAGCVWLLPL 335
>gi|115298665 neurotrimin isoform 2 [Homo sapiens]
Length = 344
Score = 320 bits (820), Expect = 1e-87
Identities = 156/326 (47%), Positives = 219/326 (67%), Gaps = 2/326 (0%)
Query: 13 SNQWLAAVLLSLCCLLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWL 72
S W L+ CL FP A+DN+ VR+G++A LRC +++ ++ AWL
Sbjct: 11 SISWAIFTGLAALCLFQGVPVRSGDATFP-KAMDNVTVRQGESATLRCTIDNRVTRVAWL 69
Query: 73 NRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVH 132
NRS+I++AG DKW +DPRV + + + YS++IQNVDV D+GPYTCSVQT + P+T +VH
Sbjct: 70 NRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVH 129
Query: 133 LTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPF-ENGQYLDIY 191
L VQV PKI +IS+D+++NEG N++LTC+ATG+PEP+++WRHISP A F +YL+I
Sbjct: 130 LIVQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQ 189
Query: 192 GITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVP 251
GITR+Q+G+YECSA NDV+ P VR+VKV VN+ P I E K V G+ G ++CE + VP
Sbjct: 190 GITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVP 249
Query: 252 PPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLP 311
F+WYK +K+L G++G+ ++N S L NV++ +GNYTCVA+NKLG TNAS+
Sbjct: 250 SAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIM 309
Query: 312 LNPPSTAQYGITGSADVLFSCWYLVL 337
L P G++ W L L
Sbjct: 310 LFGPGAVSEVSNGTSRRAGCVWLLPL 335
>gi|4505505 opioid binding protein/cell adhesion molecule-like
isoform a preproprotein [Homo sapiens]
Length = 345
Score = 320 bits (819), Expect = 2e-87
Identities = 161/329 (48%), Positives = 220/329 (66%), Gaps = 4/329 (1%)
Query: 17 LAAVLLSLCCLLPSCLPAGQS-VDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRS 75
L V L L L+P+ +P FP A+DN+ VR+G++A LRC ++D ++ AWLNRS
Sbjct: 14 LVVVSLRLLFLVPTGVPVRSGDATFP-KAMDNVTVRQGESATLRCTIDDRVTRVAWLNRS 72
Query: 76 SIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTV 135
+I++AG DKWS+DPRV I YS+ IQNVDV D+GPYTCSVQT + P+T +VHL V
Sbjct: 73 TILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV 132
Query: 136 QVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKP--FENGQYLDIYGI 193
QVPP+I +IS+D+TVNEG++VTL CLA G+PEP+++WRH+S +YL+I I
Sbjct: 133 QVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDI 192
Query: 194 TRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPP 253
RDQ+GEYECSA NDV+ PDVRKVK+ VN+ P I + K+ V+ G+ G++ CE + VP
Sbjct: 193 KRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMA 252
Query: 254 AFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 313
F+W+K E +L G G+ I+N S LT NV+++ +GNYTCVA NKLG TNAS+ L
Sbjct: 253 EFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 312
Query: 314 PPSTAQYGITGSADVLFSCWYLVLTLSSF 342
P G+ ++ L W L+ F
Sbjct: 313 GPGAVIDGVNSASRALACLWLSGTLLAHF 341
>gi|221316762 neurotrimin isoform 4 [Homo sapiens]
Length = 316
Score = 318 bits (816), Expect = 4e-87
Identities = 153/298 (51%), Positives = 216/298 (72%), Gaps = 3/298 (1%)
Query: 17 LAAVLLSLCCLLPSCLPAGQS-VDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRS 75
L V L L L+P+ +P FP A+DN+ VR+G++A LRC +++ ++ AWLNRS
Sbjct: 14 LVVVSLRLLFLVPTGVPVRSGDATFP-KAMDNVTVRQGESATLRCTIDNRVTRVAWLNRS 72
Query: 76 SIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTV 135
+I++AG DKW +DPRV + + + YS++IQNVDV D+GPYTCSVQT + P+T +VHL V
Sbjct: 73 TILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV 132
Query: 136 QVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPF-ENGQYLDIYGIT 194
QV PKI +IS+D+++NEG N++LTC+ATG+PEP+++WRHISP A F +YL+I GIT
Sbjct: 133 QVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGIT 192
Query: 195 RDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPA 254
R+Q+G+YECSA NDV+ P VR+VKV VN+ P I E K V G+ G ++CE + VP
Sbjct: 193 REQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAE 252
Query: 255 FEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
F+WYK +K+L G++G+ ++N S L NV++ +GNYTCVA+NKLG TNAS+ L
Sbjct: 253 FQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIML 310
>gi|221316757 neurotrimin isoform 3 [Homo sapiens]
Length = 355
Score = 318 bits (816), Expect = 4e-87
Identities = 153/298 (51%), Positives = 216/298 (72%), Gaps = 3/298 (1%)
Query: 17 LAAVLLSLCCLLPSCLPAGQS-VDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRS 75
L V L L L+P+ +P FP A+DN+ VR+G++A LRC +++ ++ AWLNRS
Sbjct: 14 LVVVSLRLLFLVPTGVPVRSGDATFP-KAMDNVTVRQGESATLRCTIDNRVTRVAWLNRS 72
Query: 76 SIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTV 135
+I++AG DKW +DPRV + + + YS++IQNVDV D+GPYTCSVQT + P+T +VHL V
Sbjct: 73 TILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV 132
Query: 136 QVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPF-ENGQYLDIYGIT 194
QV PKI +IS+D+++NEG N++LTC+ATG+PEP+++WRHISP A F +YL+I GIT
Sbjct: 133 QVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGIT 192
Query: 195 RDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPA 254
R+Q+G+YECSA NDV+ P VR+VKV VN+ P I E K V G+ G ++CE + VP
Sbjct: 193 REQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAE 252
Query: 255 FEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
F+WYK +K+L G++G+ ++N S L NV++ +GNYTCVA+NKLG TNAS+ L
Sbjct: 253 FQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIML 310
>gi|59939900 opioid binding protein/cell adhesion molecule-like
isoform b preproprotein [Homo sapiens]
Length = 338
Score = 316 bits (809), Expect = 2e-86
Identities = 156/329 (47%), Positives = 215/329 (65%), Gaps = 3/329 (0%)
Query: 16 WLAAVLLSLCCLLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRS 75
W+ + +P FP A+DN+ VR+G++A LRC ++D ++ AWLNRS
Sbjct: 7 WVVFSATTALLFIPGVPVRSGDATFP-KAMDNVTVRQGESATLRCTIDDRVTRVAWLNRS 65
Query: 76 SIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTV 135
+I++AG DKWS+DPRV I YS+ IQNVDV D+GPYTCSVQT + P+T +VHL V
Sbjct: 66 TILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV 125
Query: 136 QVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKP--FENGQYLDIYGI 193
QVPP+I +IS+D+TVNEG++VTL CLA G+PEP+++WRH+S +YL+I I
Sbjct: 126 QVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDI 185
Query: 194 TRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPP 253
RDQ+GEYECSA NDV+ PDVRKVK+ VN+ P I + K+ V+ G+ G++ CE + VP
Sbjct: 186 KRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMA 245
Query: 254 AFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 313
F+W+K E +L G G+ I+N S LT NV+++ +GNYTCVA NKLG TNAS+ L
Sbjct: 246 EFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 305
Query: 314 PPSTAQYGITGSADVLFSCWYLVLTLSSF 342
P G+ ++ L W L+ F
Sbjct: 306 GPGAVIDGVNSASRALACLWLSGTLLAHF 334
>gi|157819143 IgLON family member 5 [Homo sapiens]
Length = 336
Score = 259 bits (662), Expect = 3e-69
Identities = 136/304 (44%), Positives = 192/304 (63%), Gaps = 7/304 (2%)
Query: 18 AAVLLSLCCLLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRSSI 77
AA L L + L QS++F A DN V +GD A L C++++ ++ AWLNRS+I
Sbjct: 15 AAALAGLAVISRGLL--SQSLEFNSPA-DNYTVCEGDNATLSCFIDEHVTRVAWLNRSNI 71
Query: 78 IFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQV 137
++AG D+W+ DPRV + ++S+ I V + D+G YTCS QT+H P T QV+L V V
Sbjct: 72 LYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHV 131
Query: 138 PPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQ 197
P +I +IS+ +TVNEG NV L CLA G+PEP+++WR + G+ L+I I R Q
Sbjct: 132 PARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFT--SEGEILEISDIQRGQ 189
Query: 198 AGEYECSAENDV-SFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFE 256
AGEYEC N V S PD R+V V VN+ PTI ++ S GR+ L+RCE VPP F+
Sbjct: 190 AGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQ 249
Query: 257 WYKGEKKLFNG-QQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPP 315
WYK ++ L +G +G+ +Q TRS+L NV+ H+GNYTC AAN+LG ++AS+ L P
Sbjct: 250 WYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRP 309
Query: 316 STAQ 319
+ +
Sbjct: 310 GSLE 313
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 105 bits (263), Expect = 5e-23
Identities = 76/273 (27%), Positives = 117/273 (42%), Gaps = 24/273 (8%)
Query: 47 NMMVRKGDTAVLRC-YLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQI 105
N+ V G+TAVL C L + W+ W V P + D SL+I
Sbjct: 408 NVTVSPGETAVLSCRVLGEAPYNLTWVR----------DWRVLPASTGRVAQLADLSLEI 457
Query: 106 QNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGK 165
+ TD G Y C + V L V+ P++ ++ ++G V ++C A+G
Sbjct: 458 SGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGY 517
Query: 166 PEPSISWRHISPSAKP-----FENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVV 220
P P ISW S + + + L I G+ + AG Y C A N+V D V +
Sbjct: 518 PTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVG-TDQETVTLY 576
Query: 221 VNFAPTIQEIKSGT-VTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTR 279
P++ + + V G ++ CE +GVPPP WY+G G + I+ S+
Sbjct: 577 YTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRG------GLEMILAPEGSSS 630
Query: 280 SILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
L + + G YTC A N+LG +A + L
Sbjct: 631 GKLRIPAAQERDAGTYTCRAVNELGDASAEIQL 663
Score = 77.8 bits (190), Expect = 1e-14
Identities = 61/227 (26%), Positives = 93/227 (40%), Gaps = 24/227 (10%)
Query: 98 KRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVT 157
+ D SL + G Y+C + V L VQVPP+I+ + NEG +
Sbjct: 818 RADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPAS 877
Query: 158 LTCLATGKPEPSISWRHIS-------PSAKPFENGQYLDIYGITRDQAGEYECSAENDVS 210
L C+A+G P P+I+W + P + G L +D AG Y C+A N V
Sbjct: 878 LPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQD-AGAYVCTATNTVG 936
Query: 211 FPDVRKVKVVVNFAPTIQEIKSG--------TVTPGRSGLIRCEGAGVPPPAFEWYKGEK 262
F +++++ VN P I S T G + CE G PPP W K +
Sbjct: 937 FSS-QEMRLSVNTKPRIHMNGSRNANVPLQVTAKAGEEVTLDCEAKGSPPPLVTWTKDSR 995
Query: 263 KL--FNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTN 307
+ + G++ L + V G+Y C A+N G+ +
Sbjct: 996 PVPPITNRYGLL-----PSGSLRLAQVQVGDSGHYECTASNPAGSAS 1037
Score = 70.1 bits (170), Expect = 3e-12
Identities = 60/227 (26%), Positives = 91/227 (40%), Gaps = 23/227 (10%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLA 162
L+I D G YTC + + ++ L V P++ ++ D+TV G + L C A
Sbjct: 633 LRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRA 692
Query: 163 TGKPEPSISWR--------------HISPSAKPFENGQYLDIYGITRDQAGEYECSAEND 208
TG+P P+++WR S S +P + L + + Y C A N
Sbjct: 693 TGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQP--DSGVLFFESVAPEDQAPYVCEARNV 750
Query: 209 VSFPDVRKVKVVVNFAPTIQEIKSGT--VTPGRSGLIRC-EGAGVPPPAFEWYKGEKKLF 265
+V AP + T V G+ + C AG P P W K + L
Sbjct: 751 FGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLP 810
Query: 266 NGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
G + I + S L + QEH G Y+CVA N G+ + + L
Sbjct: 811 PGSRHSIRADGS----LHLDRALQEHAGRYSCVATNTAGSQHRDVEL 853
Score = 65.9 bits (159), Expect = 5e-11
Identities = 58/232 (25%), Positives = 92/232 (39%), Gaps = 13/232 (5%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTV--QVPPKIYDISNDMTVNEGTNVTLTC 160
L ++V D PY C + + L V PP+I + + V EG V+L C
Sbjct: 730 LFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPC 789
Query: 161 LA-TGKPEPSISW----RHISPSAK-PFENGQYLDIYGITRDQAGEYECSAENDVSFPDV 214
+ G+P P W R + P ++ L + ++ AG Y C A N
Sbjct: 790 IVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQH- 848
Query: 215 RKVKVVVNFAPTIQEIKSGTVT-PGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIII 273
R V++VV P I + +T G + C +GVP P W K L +
Sbjct: 849 RDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHY-- 906
Query: 274 QNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPSTAQYGITGS 325
N S L + + + G Y C A N +G ++ + L+ + + + GS
Sbjct: 907 -NVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGS 957
Score = 64.3 bits (155), Expect = 2e-10
Identities = 53/228 (23%), Positives = 93/228 (40%), Gaps = 17/228 (7%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCL 161
S +I ++G Y C+ ++ + + V PP + ++TV+ G L+C
Sbjct: 363 SWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCR 422
Query: 162 ATGKPEPSISWRHISPSAKPFENGQY-------LDIYGITRDQAGEYECSAENDVSFPDV 214
G+ +++W P G+ L+I GI G Y+C A N +
Sbjct: 423 VLGEAPYNLTWVR-DWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASN-ANGVTR 480
Query: 215 RKVKVVVNFAPTIQ-EIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIII 273
V ++V AP + S + G + C +G P P W + + L +
Sbjct: 481 ASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSR---- 536
Query: 274 QNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL---NPPSTA 318
+ + L + V E GNY+C A N++GT ++ L +PPS +
Sbjct: 537 IHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVS 584
Score = 45.8 bits (107), Expect = 6e-05
Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 3/138 (2%)
Query: 189 DIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGA 248
+I ++ + G YEC+A + + VV + P + + TV+PG + ++ C
Sbjct: 365 EILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVL 424
Query: 249 GVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNA 308
G P W + + ++ G + Q L ++ + G Y CVA+N G T A
Sbjct: 425 GEAPYNLTWVR-DWRVLPASTGRVAQLADLS--LEISGIIPTDGGRYQCVASNANGVTRA 481
Query: 309 SLPLNPPSTAQYGITGSA 326
S+ L Q I S+
Sbjct: 482 SVWLLVREAPQVSIHTSS 499
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 105 bits (263), Expect = 5e-23
Identities = 76/273 (27%), Positives = 117/273 (42%), Gaps = 24/273 (8%)
Query: 47 NMMVRKGDTAVLRC-YLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQI 105
N+ V G+TAVL C L + W+ W V P + D SL+I
Sbjct: 525 NVTVSPGETAVLSCRVLGEAPYNLTWVR----------DWRVLPASTGRVAQLADLSLEI 574
Query: 106 QNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGK 165
+ TD G Y C + V L V+ P++ ++ ++G V ++C A+G
Sbjct: 575 SGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGY 634
Query: 166 PEPSISWRHISPSAKP-----FENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVV 220
P P ISW S + + + L I G+ + AG Y C A N+V D V +
Sbjct: 635 PTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVG-TDQETVTLY 693
Query: 221 VNFAPTIQEIKSGT-VTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTR 279
P++ + + V G ++ CE +GVPPP WY+G G + I+ S+
Sbjct: 694 YTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRG------GLEMILAPEGSSS 747
Query: 280 SILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
L + + G YTC A N+LG +A + L
Sbjct: 748 GKLRIPAAQERDAGTYTCRAVNELGDASAEIQL 780
Score = 85.9 bits (211), Expect = 5e-17
Identities = 70/226 (30%), Positives = 96/226 (42%), Gaps = 15/226 (6%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLA 162
LQI+ VD+ D+G YTC+ +V L V VPP I + V E +VTL CLA
Sbjct: 1850 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLA 1909
Query: 163 TGKPEPSISW----RHISP--SAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRK 216
+G P P +SW + +S +G+ L I AG Y C A N ++R
Sbjct: 1910 SGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELR- 1968
Query: 217 VKVVVNFAP--TIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYK-GEKKLFNGQQGIII 273
+ VN P T+ G V + C G P P W K G G G +
Sbjct: 1969 YGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPG--L 2026
Query: 274 QNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPS 316
Q F +LT+ + G Y+CVA + +G + L PPS
Sbjct: 2027 QVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPS 2072
Score = 82.8 bits (203), Expect = 4e-16
Identities = 93/323 (28%), Positives = 134/323 (41%), Gaps = 32/323 (9%)
Query: 21 LLSLCCLLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRSSIIFA 80
L+ L L+P PA + P D ++VR GD AVL C + A + +
Sbjct: 3020 LVQLSVLVP---PAFRQA--PRGPQDAVLVRVGDKAVLSCETD------ALPEPTVTWYK 3068
Query: 81 GGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPK 140
G + R +R L+IQ V+D G Y+C V LTVQVPP
Sbjct: 3069 DGQPLVLAQRTQALRGGQR---LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPP- 3124
Query: 141 IYDISNDMTVNE--GTNVTLTCLATGKPEPSISW----RHISPSA--KPFENGQYLDIYG 192
++ TV++ G+ + LTC +G P P+++W + SA G L +
Sbjct: 3125 TFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSR 3184
Query: 193 ITRDQAGEYECSAENDVSFPDVRKVKVV-VNFAPTIQE---IKSGTVTPGRSGLIRCEGA 248
+ QAG Y C AEN + + RK VV V AP I+ + V G+ + CE
Sbjct: 3185 LQPAQAGTYTCVAENTQA--EARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEAD 3242
Query: 249 GVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNA 308
G PPP W K L G ++ + L + + G YTCVA N G
Sbjct: 3243 GQPPPDVAWLKDGSPL-GQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDAR 3301
Query: 309 SLPLN--PPSTAQYGITGSADVL 329
+N P T + G GS ++
Sbjct: 3302 LHTVNVLVPPTIKQGADGSGTLV 3324
Score = 82.0 bits (201), Expect = 7e-16
Identities = 60/208 (28%), Positives = 85/208 (40%), Gaps = 26/208 (12%)
Query: 112 DDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSIS 171
D + C V + +TV VPP I D D TV V LTC +TG P P++S
Sbjct: 3830 DSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVS 3889
Query: 172 WR-------------HISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVK 218
W +SPS E GQ L I+ AG Y CSA N + V
Sbjct: 3890 WSKAGAQLGARGSGYRVSPSG-ALEIGQALPIH------AGRYTCSARNSAGVAH-KHVF 3941
Query: 219 VVVNFAPTIQEIKSGT-VTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFS 277
+ V +P ++ + S L+ CE +G+P P W K + G ++
Sbjct: 3942 LTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQ 4001
Query: 278 TRSILTVTNVTQEHFGNYTCVAANKLGT 305
R + + + E GNY C+A N G+
Sbjct: 4002 LR----IAHASPEDAGNYLCIAKNSAGS 4025
Score = 80.5 bits (197), Expect = 2e-15
Identities = 61/230 (26%), Positives = 100/230 (43%), Gaps = 20/230 (8%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY---DISNDMTVNEGTNVTLT 159
L + + +G YTC + + L V VPP+I + ++V + TL
Sbjct: 2220 LYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLE 2279
Query: 160 CLATGKPEPSISW-RHISPSAKPF-----ENGQYLDIYGITRDQAGEYECSAENDVSFPD 213
C ATGKP P+++W R P GQ L + G Y C AEN +
Sbjct: 2280 CNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAE 2339
Query: 214 VRKVKVVVNFAPTI----QEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQ 269
RK ++ V P + + + T + CE G+PPPA W++GE+ + G+
Sbjct: 2340 -RKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGED 2398
Query: 270 GIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLP---LNPPS 316
++ + +L +T ++ G Y+C+A+N+ G + L PPS
Sbjct: 2399 TYLL---AGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPS 2445
Score = 79.7 bits (195), Expect = 4e-15
Identities = 63/220 (28%), Positives = 94/220 (42%), Gaps = 27/220 (12%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLA 162
L+I + D G Y C + + L VQVPP I + D++ EG++ L C A
Sbjct: 4002 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKA 4061
Query: 163 TGKPEPSISW----RHISPSAKPF---ENGQYLDIYGITRDQAGEYECSAENDVSFPDVR 215
G PEP+I+W + +S + F +G+ L + + AG Y C+AEN V R
Sbjct: 4062 RGSPEPNITWDKDGQPVSGAEGKFTIQPSGELL-VKNLEGQDAGTYTCTAENAVGRAR-R 4119
Query: 216 KVKVVVNFAPTIQEIKSGTVTPGRSGL-------IRCEGAGVPPPAFEWYKGEKKLFNGQ 268
+V + + P T PG L +RC G P P W ++ + G
Sbjct: 4120 RVHLTILVLPVF------TTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG- 4172
Query: 269 QGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNA 308
+ S L V++E G Y C A N++G T A
Sbjct: 4173 ----VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQA 4208
Score = 79.0 bits (193), Expect = 6e-15
Identities = 63/227 (27%), Positives = 96/227 (42%), Gaps = 11/227 (4%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCL 161
SL++ V V D G Y C+ + + L VQVPP++ + V G + L C+
Sbjct: 1083 SLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCV 1142
Query: 162 ATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVV 221
A G PEP +SW + + I AG Y C A N D +V++ V
Sbjct: 1143 AEGNPEPQLSWSKDGVVLQGRGPQGSVHFAAIRTSDAGRYRCEASNSAGV-DAWEVELRV 1201
Query: 222 NFAPTI-QEIKSGTV--TPGRSGLIRCEGAGVPPPAFEWYKG-EKKLFNGQQGIIIQNFS 277
P + SG + G + + C G P P W KG + +GQ G+ +
Sbjct: 1202 LEPPHWGADETSGLLERVAGENASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLE-- 1259
Query: 278 TRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL---NPPSTAQYG 321
L + +V+ G+Y C A N++G+T+ L PPS + G
Sbjct: 1260 -EGSLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDG 1305
Score = 78.6 bits (192), Expect = 8e-15
Identities = 75/270 (27%), Positives = 116/270 (42%), Gaps = 31/270 (11%)
Query: 50 VRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVD 109
+R GD LRC A++G+ R W+V+ R ++++D +Q
Sbjct: 4140 LRLGDRLWLRC-----AARGSPTPRIG--------WTVNDRPVTEGVSEQDGGSTLQRAA 4186
Query: 110 VT--DDGPYTCSVQTQ--HTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGK 165
V+ D G Y C + + T VH+ + P + + + G ++ L C+ G
Sbjct: 4187 VSREDSGTYVCWAENRVGRTQAVSFVHVK-EAPVLQGEAFSYLVEPVGGSIQLDCVVRGD 4245
Query: 166 PEPSISW------RHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKV 219
P P I W S +NG L I+ RD AG Y+C AEN++ + V +
Sbjct: 4246 PVPDIHWIKDGLPLRGSHLRHQLQNGS-LTIHRTERDDAGRYQCLAENEMGVAK-KVVIL 4303
Query: 220 VVNFAPTIQ-EIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFST 278
V+ AP Q E + TV G +RC+ G P P EW + + L ++ + + S
Sbjct: 4304 VLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGS- 4362
Query: 279 RSILTVTNVTQEHFGNYTCVAANKLGTTNA 308
L + NV G Y CVA N LG+ A
Sbjct: 4363 ---LWLENVETGDAGTYDCVAHNLLGSATA 4389
Score = 75.9 bits (185), Expect = 5e-14
Identities = 62/238 (26%), Positives = 101/238 (42%), Gaps = 38/238 (15%)
Query: 101 YSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY--DISNDMTVNE-----G 153
+ LQI N D G YTC V + H+ V +PP I D ++ V E
Sbjct: 2595 HGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVN 2654
Query: 154 TNVTLTCLATGKPEPSISW----RHISPSAK--PFENGQYLDIYGITRDQAGEYECSAEN 207
+ +TL C + P P+I W + ++PS++ G+ L I +G Y C A N
Sbjct: 2655 STLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATN 2714
Query: 208 DVSFPDVRKVKVVVNFAPTIQEI---------------KSGTVTPGRS------GLIRCE 246
V+ D + V++ P Q++ G VT R + C+
Sbjct: 2715 -VAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCD 2773
Query: 247 GAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 304
+PPP WY+ ++ L G + ++Q +L + V E+ G Y+C A+N++G
Sbjct: 2774 TNAIPPPDLTWYREDQPLSAGDEVSVLQG---GRVLQIPLVRAENAGRYSCKASNEVG 2828
Score = 74.3 bits (181), Expect = 2e-13
Identities = 72/270 (26%), Positives = 103/270 (38%), Gaps = 44/270 (16%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPK--IYDISNDMTVNEGTNVTLT 159
S+ + +D G Y C +V L V PP + S + G N +L
Sbjct: 1168 SVHFAAIRTSDAGRYRCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASLP 1227
Query: 160 CLATGKPEPSISWR--------HISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSF 211
C A G P+P ++WR H P E G L + ++ +G+YEC A N+V
Sbjct: 1228 CPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGS-LFLASVSPADSGDYECQATNEVGS 1286
Query: 212 PDVRKVKVVVNFAPTIQEIKSGTVTPGRSG---LIRCEGAGVPPPAFEWYKGEK------ 262
R+ K+VV P+I+E G +G + C+ G P P W K +
Sbjct: 1287 TS-RRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPL 1345
Query: 263 -------KLFNGQQG---IIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNAS--- 309
L GQ G ++ + S L + + G Y+C A N+ GT
Sbjct: 1346 GWAGYGWDLGWGQVGGHRLLDEGQS----LHFPRIQEGDSGLYSCRAENQAGTAQRDFHL 1401
Query: 310 LPLNPPSTAQYGIT------GSADVLFSCW 333
L L PPS G ADV CW
Sbjct: 1402 LVLTPPSVLGAGAAQEVLGLAGADVELQCW 1431
Score = 73.9 bits (180), Expect = 2e-13
Identities = 63/232 (27%), Positives = 94/232 (40%), Gaps = 19/232 (8%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY----DISNDMTVNEGTNVTL 158
LQI V + G Y+C + + L V PP I ++ ++TVN + V+L
Sbjct: 2806 LQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSL 2865
Query: 159 TCLATGKPEPSISWRH------ISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFP 212
C A G P P+ISW SP + E+GQ L + A Y C AEN
Sbjct: 2866 QCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA 2925
Query: 213 DVRKVKVVVNFAPTIQ--EIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQG 270
+ + + V P I +++ T S + C+ P P WYK + L G++
Sbjct: 2926 E-KLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEV 2984
Query: 271 IIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPSTAQ 319
++ T L + G YTC A N G + L+ PP+ Q
Sbjct: 2985 FLLPGTHT---LQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQ 3033
Score = 72.8 bits (177), Expect = 4e-13
Identities = 61/222 (27%), Positives = 96/222 (43%), Gaps = 20/222 (9%)
Query: 96 LNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKI--YDISNDMTVNEG 153
L+ ++L+I V + D G +TC + L VQVPP + + ND+ V G
Sbjct: 3362 LHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRG 3421
Query: 154 TNVTLTCLATGKPEPSISWRHISPS--AKPFENGQYLDIYGITRDQAGEYECSAENDVSF 211
+ V L C A G P P +SW ++ E G L + + +G Y C A ++
Sbjct: 3422 SLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAG- 3480
Query: 212 PDVRKVKVVVNFAPTIQEIKSGT---VTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQ 268
R ++ V P I++ T +TPG + C+ G P P W+K +GQ
Sbjct: 3481 EARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHK------DGQ 3534
Query: 269 QGIIIQNFSTRS-ILTVTNVTQEHFGNYTCVAANKLGTTNAS 309
++N S + +L V + G YTC+A + G S
Sbjct: 3535 ALTRLENNSRATRVLRVRDA-----GLYTCLAESPAGAIEKS 3571
Score = 72.4 bits (176), Expect = 6e-13
Identities = 56/214 (26%), Positives = 88/214 (41%), Gaps = 18/214 (8%)
Query: 101 YSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDI----SNDMTVNEGTNV 156
++LQ+ ++D G YTC V L+V VPP + + V G
Sbjct: 2991 HTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKA 3050
Query: 157 TLTCLATGKPEPSISWRH------ISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVS 210
L+C PEP+++W ++ + GQ L+I G Y C N V+
Sbjct: 3051 VLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSN-VA 3109
Query: 211 FPDVRKVKVVVNFAPTIQEIKSGTVT--PGRSGLIRCEGAGVPPPAFEWYKGEKKL-FNG 267
VR + V PT + K+ TV+ G ++ C+ +GVP P W K + +
Sbjct: 3110 GEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSA 3169
Query: 268 QQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAAN 301
G++ S L ++ + G YTCVA N
Sbjct: 3170 VHGVV----SRGGRLQLSRLQPAQAGTYTCVAEN 3199
Score = 72.0 bits (175), Expect = 8e-13
Identities = 66/251 (26%), Positives = 103/251 (41%), Gaps = 20/251 (7%)
Query: 98 KRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVT 157
+R LQ+Q + D G Y+C+ + ++ + + P I + V+
Sbjct: 3632 ERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTAL 3691
Query: 158 LTCLATGKPEPSISWRH----ISPSAKPFE---NGQYLDIYGITRDQAGEYECSAENDVS 210
L C A G P P +SWR + P + FE G L I + AG Y C A N
Sbjct: 3692 LPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGS-LRIQPVLAQDAGHYLCLASNSAG 3750
Query: 211 FPDVRKVKVVVNFAPTIQEIKSG-TVTPGRSGLIRCEGAGVPPPAFEWYK-GEKKLFNGQ 268
D + + V P I S T+T L+ CE +G P P W+K G+K F Q
Sbjct: 3751 -SDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQ 3809
Query: 269 QGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPSTA----QYG 321
QG + L +T + + CV +N++G + + PP+ A +
Sbjct: 3810 QG--AYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFT 3867
Query: 322 ITGSADVLFSC 332
+T A V+ +C
Sbjct: 3868 VTMMAPVVLTC 3878
Score = 70.9 bits (172), Expect = 2e-12
Identities = 61/224 (27%), Positives = 85/224 (37%), Gaps = 30/224 (13%)
Query: 101 YSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY--DISNDMTVNEGTNVTL 158
+ L++ D G Y+C + + V VPP I D+ + V +G L
Sbjct: 2406 WMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHL 2465
Query: 159 TCLATGKPEPSISW------------RHISPSAKPFENGQYLDIYGITRDQAGEYECSAE 206
C TG P+P ++W HISP +G L + AG Y C A
Sbjct: 2466 MCNVTGHPQPKLTWFKDGRPLARGDAHHISP------DGVLLQVLQANLSSAGHYSCIAA 2519
Query: 207 NDVSFPDVRKVKVVVNFAPTI------QEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKG 260
N V + ++ V APTI + TVT + CE P P W K
Sbjct: 2520 NAVG-EKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMK- 2577
Query: 261 EKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 304
+ F + IQ L + N +E G YTCV N+LG
Sbjct: 2578 DGAPFEASRN--IQLLPGTHGLQILNAQKEDAGQYTCVVTNELG 2619
Score = 70.1 bits (170), Expect = 3e-12
Identities = 60/227 (26%), Positives = 91/227 (40%), Gaps = 23/227 (10%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLA 162
L+I D G YTC + + ++ L V P++ ++ D+TV G + L C A
Sbjct: 750 LRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRA 809
Query: 163 TGKPEPSISWR--------------HISPSAKPFENGQYLDIYGITRDQAGEYECSAEND 208
TG+P P+++WR S S +P + L + + Y C A N
Sbjct: 810 TGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQP--DSGVLFFESVAPEDQAPYVCEARNV 867
Query: 209 VSFPDVRKVKVVVNFAPTIQEIKSGT--VTPGRSGLIRC-EGAGVPPPAFEWYKGEKKLF 265
+V AP + T V G+ + C AG P P W K + L
Sbjct: 868 FGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLP 927
Query: 266 NGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
G + I + S L + QEH G Y+CVA N G+ + + L
Sbjct: 928 PGSRHSIRADGS----LHLDRALQEHAGRYSCVATNTAGSQHRDVEL 970
Score = 68.9 bits (167), Expect = 6e-12
Identities = 66/256 (25%), Positives = 96/256 (37%), Gaps = 38/256 (14%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCL 161
SL+IQ V D G Y C L V PP I +++T+ T L C
Sbjct: 3727 SLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCE 3786
Query: 162 ATGKPEPSISWRHISPSAKPFENGQYLDI------YGITRDQA-----------GEYECS 204
A+G P+P + W +++GQ LD Y + A ++EC
Sbjct: 3787 ASGSPKPLVVW---------WKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECV 3837
Query: 205 AENDVSFPDVRKVKVVVNFAPTIQEIKSG-TVTPGRSGLIRCEGAGVPPPAFEWYKGEKK 263
N+V R +V V+ PTI + ++ TVT ++ C G+P P W K +
Sbjct: 3838 VSNEVGEAH-RLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQ 3896
Query: 264 LFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGT-------TNASLPLNPPS 316
L G + S L + H G YTC A N G T + P+ P
Sbjct: 3897 LGARGSGYRV---SPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPL 3953
Query: 317 TAQYGITGSADVLFSC 332
+ +VL C
Sbjct: 3954 PSVVRAVAEEEVLLPC 3969
Score = 68.6 bits (166), Expect = 8e-12
Identities = 60/237 (25%), Positives = 98/237 (41%), Gaps = 24/237 (10%)
Query: 85 WSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDI 144
W D +S ++ SLQ++ V D G Y+C ++ LTV PP I D
Sbjct: 3440 WMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDS 3499
Query: 145 S--NDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYE 202
++++ G + L C A G P+P+I+W + EN RD AG Y
Sbjct: 3500 GQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRD-AGLYT 3558
Query: 203 CSAENDVSFPDVRKVKVVVNFAPTIQEIKSGT----VTPGRSGLIRCEGAGVPPPAFEWY 258
C AE+ + + +V V P I + + PG+ ++ C P P W+
Sbjct: 3559 CLAESPAGAIE-KSFRVRVQAPPNIVGPRGPRFVVGLAPGQL-VLECSVEAEPAPKITWH 3616
Query: 259 KGEKKLFNGQQGIIIQ-----NFSTRS-ILTVTNVTQEHFGNYTCVAANKLGTTNAS 309
+ GI++Q F R L + ++ G+Y+C A N G+T+ +
Sbjct: 3617 R---------DGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVA 3664
Score = 67.8 bits (164), Expect = 1e-11
Identities = 59/230 (25%), Positives = 90/230 (39%), Gaps = 19/230 (8%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY--DISNDMTVNEGTNVTLT 159
SL + D G Y+C + Q HL V PP + + ++ G +V L
Sbjct: 1370 SLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQ 1429
Query: 160 CLATGKPEPSISWRHI-------SPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFP 212
C +G P P + W P + E+GQ L I G G Y+C A +
Sbjct: 1430 CWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAG-Q 1488
Query: 213 DVRKVKVVVNFAPTI-QEIKSGTVTPGRSGLIR--CEGAGVPPPAFEWYKGEKKLFNGQQ 269
R ++ V+ PTI ++G V L++ CE GVP P W+K L +
Sbjct: 1489 QARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTK 1548
Query: 270 GIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPS 316
+ + L + G YTC A+N +G + L+ PP+
Sbjct: 1549 VVYTRGGRQ---LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPT 1595
Score = 67.8 bits (164), Expect = 1e-11
Identities = 57/223 (25%), Positives = 91/223 (40%), Gaps = 16/223 (7%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNE---GTNVTLT 159
LQ+ +D G YTC L V VPP I V + G V L
Sbjct: 1558 LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALE 1617
Query: 160 CLATGKPEPSISWRHIS-PSAKPFE-----NGQYLDIYGITRDQAGEYECSAENDVSFPD 213
C+A G P P++SW H P A+ E +G L + +G Y C A +
Sbjct: 1618 CVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAG-EA 1676
Query: 214 VRKVKVVVNFAPTI---QEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQG 270
V + V V P + + + T G+ + C+ +G P P +W + + ++
Sbjct: 1677 VLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRP---AEEL 1733
Query: 271 IIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 313
+Q S + L + +V +H G + C A N+ GT A + ++
Sbjct: 1734 AGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVS 1776
Score = 67.4 bits (163), Expect = 2e-11
Identities = 65/249 (26%), Positives = 98/249 (39%), Gaps = 24/249 (9%)
Query: 96 LNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKI---YDISNDMTVNE 152
L + SL ++ G Y+C + + L+V VPP++ D ++T
Sbjct: 2307 LQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAAL 2366
Query: 153 GTNVTLTCLATGKPEPSISWRHISPSAKPFEN------GQYLDIYGITRDQAGEYECSAE 206
+ +TL C A G P P+I W P E+ G L + +G Y C A
Sbjct: 2367 HSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLAS 2426
Query: 207 NDVSFPDVRKVKVVVNFAPTIQE------IKSGTVTPGRSGLIRCEGAGVPPPAFEWYKG 260
N+ R V V P+I+ IK V G++ + C G P P W+K
Sbjct: 2427 NEAG-EARRNFSVEVLVPPSIENEDLEEVIK---VLDGQTAHLMCNVTGHPQPKLTWFKD 2482
Query: 261 EKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG--TTNASLPLNPPSTA 318
+ L G I + +L V G+Y+C+AAN +G T + L + T
Sbjct: 2483 GRPLARGDAHHISPD---GVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTI 2539
Query: 319 QYGITGSAD 327
G SAD
Sbjct: 2540 LGGAEDSAD 2548
Score = 65.9 bits (159), Expect = 5e-11
Identities = 64/257 (24%), Positives = 96/257 (37%), Gaps = 32/257 (12%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVN--EGTNVTLT 159
SL + +V D G Y C + + + L V VPP I + V+ G ++TL
Sbjct: 1262 SLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLE 1321
Query: 160 CLATGKPEPSISWRHISPSA---------------------KPFENGQYLDIYGITRDQA 198
C A G P P I W + + + GQ L I +
Sbjct: 1322 CDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDS 1381
Query: 199 GEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGL---IRCEGAGVPPPAF 255
G Y C AEN R ++V P++ + G +G ++C +GVP P
Sbjct: 1382 GLYSCRAENQAGTAQ-RDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQV 1440
Query: 256 EWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN-- 313
EW K + + G + +Q +T ++V E G Y CVA + G L
Sbjct: 1441 EWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDE--GRYQCVAFSPAGQQARDFQLRVH 1498
Query: 314 -PPSTAQYGITGSADVL 329
PP+ TG V+
Sbjct: 1499 APPTIWGSNETGEVAVM 1515
Score = 64.3 bits (155), Expect = 2e-10
Identities = 53/228 (23%), Positives = 93/228 (40%), Gaps = 17/228 (7%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCL 161
S +I ++G Y C+ ++ + + V PP + ++TV+ G L+C
Sbjct: 480 SWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCR 539
Query: 162 ATGKPEPSISWRHISPSAKPFENGQY-------LDIYGITRDQAGEYECSAENDVSFPDV 214
G+ +++W P G+ L+I GI G Y+C A N +
Sbjct: 540 VLGEAPYNLTWVR-DWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASN-ANGVTR 597
Query: 215 RKVKVVVNFAPTIQ-EIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIII 273
V ++V AP + S + G + C +G P P W + + L +
Sbjct: 598 ASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSR---- 653
Query: 274 QNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL---NPPSTA 318
+ + L + V E GNY+C A N++GT ++ L +PPS +
Sbjct: 654 IHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVS 701
Score = 64.3 bits (155), Expect = 2e-10
Identities = 56/220 (25%), Positives = 87/220 (39%), Gaps = 13/220 (5%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTV--QVPPKIYDISNDMTVNEGTNVTLTC 160
L ++V D PY C + + L V PP+I + + V EG V+L C
Sbjct: 847 LFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPC 906
Query: 161 LA-TGKPEPSISW----RHISPSAK-PFENGQYLDIYGITRDQAGEYECSAENDVSFPDV 214
+ G+P P W R + P ++ L + ++ AG Y C A N
Sbjct: 907 IVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQH- 965
Query: 215 RKVKVVVNFAPTIQEIKSGTVT-PGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIII 273
R V++VV P I + +T G + C +GVP P W K L +
Sbjct: 966 RDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHY-- 1023
Query: 274 QNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 313
N S L + + + G Y C A N +G ++ + L+
Sbjct: 1024 -NVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLS 1062
Score = 60.5 bits (145), Expect = 2e-09
Identities = 61/233 (26%), Positives = 92/233 (39%), Gaps = 25/233 (10%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLA 162
L + + +D G Y+C + V L V +PP I +++V +V L C +
Sbjct: 2035 LTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQS 2094
Query: 163 TGKPEPSISW----RHISP-------SAKPFENGQYLDIYGITRDQAGEYECSAENDVSF 211
P P +SW R + P + K D++ AG Y C A N
Sbjct: 2095 HAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVW-----DAGHYTCEALNQAGH 2149
Query: 212 PDVRKVKVVVNFAPT--IQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQ 269
+ + + V AP ++E + TV G + CE GVP P W K + L +
Sbjct: 2150 SE-KHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPL--PGE 2206
Query: 270 GIIIQNFSTRSILTVTNVTQ-EHFGNYTCVAANKLGTTNASLPLN---PPSTA 318
G +Q+ S L Q G YTC +N +G ++ L L PP A
Sbjct: 2207 GAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIA 2259
Score = 58.9 bits (141), Expect = 7e-09
Identities = 62/238 (26%), Positives = 87/238 (36%), Gaps = 29/238 (12%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHL---TVQVPPKIY---DISNDMTVNEGTN 155
SL ++ + +D G YTC H P L V VPP I D S + G
Sbjct: 3274 SLVLKGLRASDAGAYTC---VAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGEL 3330
Query: 156 VTLTCLATGKPEPSISWRH------ISPSAKPFENGQYLDIYGITRDQAGEYECSAENDV 209
VT+ C G P +SW +S +G L I + AG + C A +
Sbjct: 3331 VTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPA 3390
Query: 210 SFPDVRKVKVVVNFAPTIQEIK-SGTVTPGRSGLIR--CEGAGVPPPAFEWYKGEKKLFN 266
D R + V P ++ ++ V R L+ CE GVP P W K + L +
Sbjct: 3391 GVAD-RNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLS 3449
Query: 267 GQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL---NPPSTAQYG 321
Q+ L + V G Y+CVA ++ G L PP G
Sbjct: 3450 -------QSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSG 3500
Score = 57.0 bits (136), Expect = 3e-08
Identities = 39/132 (29%), Positives = 60/132 (45%), Gaps = 9/132 (6%)
Query: 98 KRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVT 157
+ D SL + G Y+C + V L VQVPP+I+ + NEG +
Sbjct: 935 RADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPAS 994
Query: 158 LTCLATGKPEPSISWRHIS-------PSAKPFENGQYLDIYGITRDQAGEYECSAENDVS 210
L C+A+G P P+I+W + P + G L +D AG Y C+A N V
Sbjct: 995 LPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQD-AGAYVCTATNTVG 1053
Query: 211 FPDVRKVKVVVN 222
F +++++ VN
Sbjct: 1054 FSS-QEMRLSVN 1064
Score = 52.8 bits (125), Expect = 5e-07
Identities = 38/125 (30%), Positives = 51/125 (40%), Gaps = 7/125 (5%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCL 161
SL I + D G Y C + + V L +Q P DMTV G +V L C
Sbjct: 4272 SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQ 4331
Query: 162 ATGKPEPSISW------RHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVR 215
ATG+P P+I W S + +G L + + AG Y+C A N + R
Sbjct: 4332 ATGEPTPTIEWLQAGQPLRASRRLRTLPDGS-LWLENVETGDAGTYDCVAHNLLGSATAR 4390
Query: 216 KVKVV 220
VV
Sbjct: 4391 AFLVV 4395
Score = 45.8 bits (107), Expect = 6e-05
Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 3/138 (2%)
Query: 189 DIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGA 248
+I ++ + G YEC+A + + VV + P + + TV+PG + ++ C
Sbjct: 482 EILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVL 541
Query: 249 GVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNA 308
G P W + + ++ G + Q L ++ + G Y CVA+N G T A
Sbjct: 542 GEAPYNLTWVR-DWRVLPASTGRVAQLADLS--LEISGIIPTDGGRYQCVASNANGVTRA 598
Query: 309 SLPLNPPSTAQYGITGSA 326
S+ L Q I S+
Sbjct: 599 SVWLLVREAPQVSIHTSS 616
Score = 35.8 bits (81), Expect = 0.060
Identities = 30/133 (22%), Positives = 49/133 (36%), Gaps = 11/133 (8%)
Query: 198 AGEYECSAENDVSFPDVRKVKVVVNFAPTIQE-IKSGTVTPGRSGLIRCEGAGVPPPAFE 256
+G YEC+A N R V + V P +Q + V G + + C G P P
Sbjct: 1094 SGHYECTASNPAGSASHRYV-LGVQVPPQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLS 1152
Query: 257 WYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPS 316
W K G+++Q + + + G Y C A+N G + L
Sbjct: 1153 WSK---------DGVVLQGRGPQGSVHFAAIRTSDAGRYRCEASNSAGVDAWEVELRVLE 1203
Query: 317 TAQYGITGSADVL 329
+G ++ +L
Sbjct: 1204 PPHWGADETSGLL 1216
Score = 28.9 bits (63), Expect = 7.3
Identities = 25/95 (26%), Positives = 34/95 (35%), Gaps = 12/95 (12%)
Query: 47 NMMVRKGDTAVLRCYLEDGASKGA-WLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQI 105
+M VR GD LRC + WL + R S D SL +
Sbjct: 4317 DMTVRSGDDVALRCQATGEPTPTIEWLQAGQPL-----------RASRRLRTLPDGSLWL 4365
Query: 106 QNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPK 140
+NV+ D G Y C T + L V+ P+
Sbjct: 4366 ENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 4400
>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
sapiens]
Length = 790
Score = 105 bits (263), Expect = 5e-23
Identities = 76/273 (27%), Positives = 117/273 (42%), Gaps = 24/273 (8%)
Query: 47 NMMVRKGDTAVLRC-YLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQI 105
N+ V G+TAVL C L + W+ W V P + D SL+I
Sbjct: 524 NVTVSPGETAVLSCRVLGEAPYNLTWVR----------DWRVLPASTGRVAQLADLSLEI 573
Query: 106 QNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGK 165
+ TD G Y C + V L V+ P++ ++ ++G V ++C A+G
Sbjct: 574 SGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGY 633
Query: 166 PEPSISWRHISPSAKP-----FENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVV 220
P P ISW S + + + L I G+ + AG Y C A N+V D V +
Sbjct: 634 PTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVG-TDQETVTLY 692
Query: 221 VNFAPTIQEIKSGT-VTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTR 279
P++ + + V G ++ CE +GVPPP WY+G G + I+ S+
Sbjct: 693 YTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRG------GLEMILAPEGSSS 746
Query: 280 SILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
L + + G YTC A N+LG +A + L
Sbjct: 747 GKLRIPAAQERDAGTYTCRAVNELGDASAEIQL 779
Score = 64.3 bits (155), Expect = 2e-10
Identities = 53/228 (23%), Positives = 93/228 (40%), Gaps = 17/228 (7%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCL 161
S +I ++G Y C+ ++ + + V PP + ++TV+ G L+C
Sbjct: 479 SWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCR 538
Query: 162 ATGKPEPSISWRHISPSAKPFENGQY-------LDIYGITRDQAGEYECSAENDVSFPDV 214
G+ +++W P G+ L+I GI G Y+C A N +
Sbjct: 539 VLGEAPYNLTWVR-DWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASN-ANGVTR 596
Query: 215 RKVKVVVNFAPTIQ-EIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIII 273
V ++V AP + S + G + C +G P P W + + L +
Sbjct: 597 ASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSR---- 652
Query: 274 QNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL---NPPSTA 318
+ + L + V E GNY+C A N++GT ++ L +PPS +
Sbjct: 653 IHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVS 700
Score = 45.8 bits (107), Expect = 6e-05
Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 3/138 (2%)
Query: 189 DIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGA 248
+I ++ + G YEC+A + + VV + P + + TV+PG + ++ C
Sbjct: 481 EILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVL 540
Query: 249 GVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNA 308
G P W + + ++ G + Q L ++ + G Y CVA+N G T A
Sbjct: 541 GEAPYNLTWVR-DWRVLPASTGRVAQLADLS--LEISGIIPTDGGRYQCVASNANGVTRA 597
Query: 309 SLPLNPPSTAQYGITGSA 326
S+ L Q I S+
Sbjct: 598 SVWLLVREAPQVSIHTSS 615
>gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]
Length = 1018
Score = 99.4 bits (246), Expect = 4e-21
Identities = 65/226 (28%), Positives = 106/226 (46%), Gaps = 11/226 (4%)
Query: 87 VDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISN 146
++P S + ++ L+I N+ + D+G Y C + Q + VQ P+ + N
Sbjct: 279 LEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHIN 338
Query: 147 DMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAE 206
D V+ G+++ C+ATGKP P+I W + + G+ L +Y +T + AG Y+C AE
Sbjct: 339 DTEVDIGSDLYWPCVATGKPIPTIRW---LKNGYAYHKGE-LRLYDVTFENAGMYQCIAE 394
Query: 207 NDVSFPDVRKVKVVVNFAPTIQ---EIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKK 263
N ++ APT + K G +I C+ P P F W KG +
Sbjct: 395 NTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEW 454
Query: 264 LFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNAS 309
L N + +I ++ S L + N+T+ G YTC A N G N++
Sbjct: 455 LVNSSRILIWEDGS----LEINNITRNDGGIYTCFAENNRGKANST 496
Score = 82.0 bits (201), Expect = 7e-16
Identities = 78/292 (26%), Positives = 113/292 (38%), Gaps = 42/292 (14%)
Query: 40 FPWAAVDNMMVRKGDTAVLRC----YLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSIST 95
FP + V++G VL C + D S LN + ++D R +S
Sbjct: 138 FPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFI------TMDKRRFVSQ 191
Query: 96 LNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTM----------QVHLTVQVPPKIYDIS 145
N +L I NV+ +D G Y+C V + +++ T P I
Sbjct: 192 TNG---NLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQF 248
Query: 146 NDMTVNEGTNVTLTCLATGKPEPSISWRHI----SPSAKPFENGQYLDIYGITRDQAGEY 201
D+ G NVTL C A G P P I WR + +A+ +G L I+ I + G Y
Sbjct: 249 KDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDEGIY 308
Query: 202 ECSAENDVSFPDVRKVKVVVN-FAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKG 260
EC AEN + D + ++ V F ++ I V G C G P P W K
Sbjct: 309 ECEAEN-IRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKN 367
Query: 261 EKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
G+ L + +VT E+ G Y C+A N G A+ L
Sbjct: 368 GYAYHKGE-------------LRLYDVTFENAGMYQCIAENTYGAIYANAEL 406
Score = 52.0 bits (123), Expect = 8e-07
Identities = 51/224 (22%), Positives = 89/224 (39%), Gaps = 15/224 (6%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDIS---NDMTVNEGTNVTLT 159
L++ +V + G Y C + + L + ++++ + +G V +
Sbjct: 376 LRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIE 435
Query: 160 CLATGKPEPSISWRH------ISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPD 213
C P+P SW S +E+G L+I ITR+ G Y C AEN+ +
Sbjct: 436 CKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGS-LEINNITRNDGGIYTCFAENNRGKAN 494
Query: 214 VRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPP--AFEW-YKGEKKLFNGQQG 270
V+ + I + +T G + ++C + P F W + G FN +
Sbjct: 495 STGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENI 554
Query: 271 IIIQNF--STRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
+NF + L + N +H G YTC A + ++AS L
Sbjct: 555 HYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADL 598
Score = 42.4 bits (98), Expect = 6e-04
Identities = 54/230 (23%), Positives = 84/230 (36%), Gaps = 43/230 (18%)
Query: 48 MMVRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQN 107
++ KG ++ C K + ++ G +W V+ S L D SL+I N
Sbjct: 424 ILAAKGGRVIIEC-------KPKAAPKPKFSWSKGTEWLVN---SSRILIWEDGSLEINN 473
Query: 108 VDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY--DISNDMTVNEGTNVTLTCLATGK 165
+ D G YTC + L + P +I I+ D+TV E N T+ C A+
Sbjct: 474 ITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGE--NATMQCAASFD 531
Query: 166 PEPSIS--WR-------------HISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVS 210
P ++ W H + NG+ L I AG Y C+A+
Sbjct: 532 PALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELL-IRNAQLKHAGRYTCTAQT--- 587
Query: 211 FPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKG 260
+V N + + + G PG G +R E A W +G
Sbjct: 588 --------IVDNSSASADLVVRG--PPGPPGGLRIEDIRATSVALTWSRG 627
>gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens]
Length = 1007
Score = 99.4 bits (246), Expect = 4e-21
Identities = 65/226 (28%), Positives = 106/226 (46%), Gaps = 11/226 (4%)
Query: 87 VDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISN 146
++P S + ++ L+I N+ + D+G Y C + Q + VQ P+ + N
Sbjct: 268 LEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHIN 327
Query: 147 DMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAE 206
D V+ G+++ C+ATGKP P+I W + + G+ L +Y +T + AG Y+C AE
Sbjct: 328 DTEVDIGSDLYWPCVATGKPIPTIRW---LKNGYAYHKGE-LRLYDVTFENAGMYQCIAE 383
Query: 207 NDVSFPDVRKVKVVVNFAPTIQ---EIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKK 263
N ++ APT + K G +I C+ P P F W KG +
Sbjct: 384 NTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEW 443
Query: 264 LFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNAS 309
L N + +I ++ S L + N+T+ G YTC A N G N++
Sbjct: 444 LVNSSRILIWEDGS----LEINNITRNDGGIYTCFAENNRGKANST 485
Score = 82.0 bits (201), Expect = 7e-16
Identities = 78/292 (26%), Positives = 113/292 (38%), Gaps = 42/292 (14%)
Query: 40 FPWAAVDNMMVRKGDTAVLRC----YLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSIST 95
FP + V++G VL C + D S LN + ++D R +S
Sbjct: 127 FPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFI------TMDKRRFVSQ 180
Query: 96 LNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTM----------QVHLTVQVPPKIYDIS 145
N +L I NV+ +D G Y+C V + +++ T P I
Sbjct: 181 TNG---NLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQF 237
Query: 146 NDMTVNEGTNVTLTCLATGKPEPSISWRHI----SPSAKPFENGQYLDIYGITRDQAGEY 201
D+ G NVTL C A G P P I WR + +A+ +G L I+ I + G Y
Sbjct: 238 KDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDEGIY 297
Query: 202 ECSAENDVSFPDVRKVKVVVN-FAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKG 260
EC AEN + D + ++ V F ++ I V G C G P P W K
Sbjct: 298 ECEAEN-IRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKN 356
Query: 261 EKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
G+ L + +VT E+ G Y C+A N G A+ L
Sbjct: 357 GYAYHKGE-------------LRLYDVTFENAGMYQCIAENTYGAIYANAEL 395
Score = 52.0 bits (123), Expect = 8e-07
Identities = 51/224 (22%), Positives = 89/224 (39%), Gaps = 15/224 (6%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDIS---NDMTVNEGTNVTLT 159
L++ +V + G Y C + + L + ++++ + +G V +
Sbjct: 365 LRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIE 424
Query: 160 CLATGKPEPSISWRH------ISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPD 213
C P+P SW S +E+G L+I ITR+ G Y C AEN+ +
Sbjct: 425 CKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGS-LEINNITRNDGGIYTCFAENNRGKAN 483
Query: 214 VRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPP--AFEW-YKGEKKLFNGQQG 270
V+ + I + +T G + ++C + P F W + G FN +
Sbjct: 484 STGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENI 543
Query: 271 IIIQNF--STRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
+NF + L + N +H G YTC A + ++AS L
Sbjct: 544 HYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADL 587
Score = 42.4 bits (98), Expect = 6e-04
Identities = 54/230 (23%), Positives = 84/230 (36%), Gaps = 43/230 (18%)
Query: 48 MMVRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQN 107
++ KG ++ C K + ++ G +W V+ S L D SL+I N
Sbjct: 413 ILAAKGGRVIIEC-------KPKAAPKPKFSWSKGTEWLVN---SSRILIWEDGSLEINN 462
Query: 108 VDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY--DISNDMTVNEGTNVTLTCLATGK 165
+ D G YTC + L + P +I I+ D+TV E N T+ C A+
Sbjct: 463 ITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGE--NATMQCAASFD 520
Query: 166 PEPSIS--WR-------------HISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVS 210
P ++ W H + NG+ L I AG Y C+A+
Sbjct: 521 PALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELL-IRNAQLKHAGRYTCTAQT--- 576
Query: 211 FPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKG 260
+V N + + + G PG G +R E A W +G
Sbjct: 577 --------IVDNSSASADLVVRG--PPGPPGGLRIEDIRATSVALTWSRG 616
>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
sapiens]
Length = 848
Score = 97.4 bits (241), Expect = 2e-20
Identities = 66/216 (30%), Positives = 96/216 (44%), Gaps = 15/216 (6%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLA 162
L I+ VD D+ Y C + + + +HL V PKI + N + VTLTC A
Sbjct: 272 LTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEA 331
Query: 163 TGKPEPSISW----RHISPSAKPFENGQY---------LDIYGITRDQAGEYECSAENDV 209
+G P PSI+W R+IS K + L + I AGEY C+A N +
Sbjct: 332 SGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTI 391
Query: 210 SFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYK-GEKKLFNGQ 268
D + + + V +AP +Q + G I CE P W++ G+ +
Sbjct: 392 G-QDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNY 450
Query: 269 QGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 304
I I N + S L VT ++ FGNY C A N++G
Sbjct: 451 SNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIG 486
Score = 80.9 bits (198), Expect = 2e-15
Identities = 62/230 (26%), Positives = 103/230 (44%), Gaps = 23/230 (10%)
Query: 103 LQIQNVDVTDDGPYTCS--VQTQHTPRTMQVHLTVQVPPKIYDISN--DMTVNEGTNVTL 158
LQI+ + TD+G Y C + + + + V VPP I N + T N G +VTL
Sbjct: 174 LQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTL 233
Query: 159 TCLATGKPEPSISWRHISPSAKPFENGQ---------YLDIYGITRDQAGEYECSAENDV 209
C A G PEP++SW + E+ + L I + ++ EY C AEN
Sbjct: 234 VCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKA 293
Query: 210 SFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGL-IRCEGAGVPPPAFEW------YKGEK 262
D + + V P I +++ T + + CE +G P P+ W E+
Sbjct: 294 GEQDA-TIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEE 352
Query: 263 KLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
K +G +++++ + S LT+ ++ G Y C A+N +G + S+ L
Sbjct: 353 KTLDGH--MVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYL 400
Score = 77.4 bits (189), Expect = 2e-14
Identities = 62/239 (25%), Positives = 100/239 (41%), Gaps = 20/239 (8%)
Query: 90 RVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY--DISND 147
R+S+ + +L I N ++ D G Y C V T + + V++ K+ +
Sbjct: 68 RISVVWNDDSSSTLTIYNANIDDAGIYKC-VVTGEDGSESEATVNVKIFQKLMFKNAPTP 126
Query: 148 MTVNEGTNVTLTCLATGKPEPSISWRH-----ISPSAKPF--ENGQYLDIYGITRDQAGE 200
EG + + C P+I W+H I F + YL I GI + G
Sbjct: 127 QEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGT 186
Query: 201 YECS----AENDVSFPDVRKVKVVVNFAPTI---QEIKSGTVTPGRSGLIRCEGAGVPPP 253
Y C A +++F D ++V+VN PTI Q I + T G+S + C+ G P P
Sbjct: 187 YRCEGRILARGEINFKD---IQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEP 243
Query: 254 AFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
W K +++ + S LT+ V + Y C+A NK G +A++ L
Sbjct: 244 TMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHL 302
Score = 45.4 bits (106), Expect = 8e-05
Identities = 34/142 (23%), Positives = 62/142 (43%), Gaps = 13/142 (9%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCL 161
SL ++++ TD G Y C+ + ++L VQ PK+ T EG V +TC
Sbjct: 369 SLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW-EGNQVNITCE 427
Query: 162 ATGKPEPSISW---RHISPSAK-------PFENGQYLDIYGITRDQAGEYECSAENDVSF 211
P +ISW + PS+ + YL++ + + G Y C+A N +
Sbjct: 428 VFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQ 487
Query: 212 PDVRKVKVVVN--FAPTIQEIK 231
+ + V + +P+I +++
Sbjct: 488 ESLEFILVQADTPSSPSIDQVE 509
Score = 33.9 bits (76), Expect = 0.23
Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 3/76 (3%)
Query: 233 GTVTPGRSGLIRCEGAG-VPPPAFEWYK--GEKKLFNGQQGIIIQNFSTRSILTVTNVTQ 289
G ++ G S C+ AG W+ GEK N Q+ ++ N + S LT+ N
Sbjct: 29 GEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANI 88
Query: 290 EHFGNYTCVAANKLGT 305
+ G Y CV + G+
Sbjct: 89 DDAGIYKCVVTGEDGS 104
>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
sapiens]
Length = 761
Score = 97.4 bits (241), Expect = 2e-20
Identities = 66/216 (30%), Positives = 96/216 (44%), Gaps = 15/216 (6%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLA 162
L I+ VD D+ Y C + + + +HL V PKI + N + VTLTC A
Sbjct: 272 LTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEA 331
Query: 163 TGKPEPSISW----RHISPSAKPFENGQY---------LDIYGITRDQAGEYECSAENDV 209
+G P PSI+W R+IS K + L + I AGEY C+A N +
Sbjct: 332 SGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTI 391
Query: 210 SFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYK-GEKKLFNGQ 268
D + + + V +AP +Q + G I CE P W++ G+ +
Sbjct: 392 G-QDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNY 450
Query: 269 QGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 304
I I N + S L VT ++ FGNY C A N++G
Sbjct: 451 SNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIG 486
Score = 80.9 bits (198), Expect = 2e-15
Identities = 62/230 (26%), Positives = 103/230 (44%), Gaps = 23/230 (10%)
Query: 103 LQIQNVDVTDDGPYTCS--VQTQHTPRTMQVHLTVQVPPKIYDISN--DMTVNEGTNVTL 158
LQI+ + TD+G Y C + + + + V VPP I N + T N G +VTL
Sbjct: 174 LQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTL 233
Query: 159 TCLATGKPEPSISWRHISPSAKPFENGQ---------YLDIYGITRDQAGEYECSAENDV 209
C A G PEP++SW + E+ + L I + ++ EY C AEN
Sbjct: 234 VCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKA 293
Query: 210 SFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGL-IRCEGAGVPPPAFEW------YKGEK 262
D + + V P I +++ T + + CE +G P P+ W E+
Sbjct: 294 GEQDA-TIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEE 352
Query: 263 KLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
K +G +++++ + S LT+ ++ G Y C A+N +G + S+ L
Sbjct: 353 KTLDGH--MVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYL 400
Score = 77.4 bits (189), Expect = 2e-14
Identities = 62/239 (25%), Positives = 100/239 (41%), Gaps = 20/239 (8%)
Query: 90 RVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY--DISND 147
R+S+ + +L I N ++ D G Y C V T + + V++ K+ +
Sbjct: 68 RISVVWNDDSSSTLTIYNANIDDAGIYKC-VVTGEDGSESEATVNVKIFQKLMFKNAPTP 126
Query: 148 MTVNEGTNVTLTCLATGKPEPSISWRH-----ISPSAKPF--ENGQYLDIYGITRDQAGE 200
EG + + C P+I W+H I F + YL I GI + G
Sbjct: 127 QEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGT 186
Query: 201 YECS----AENDVSFPDVRKVKVVVNFAPTI---QEIKSGTVTPGRSGLIRCEGAGVPPP 253
Y C A +++F D ++V+VN PTI Q I + T G+S + C+ G P P
Sbjct: 187 YRCEGRILARGEINFKD---IQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEP 243
Query: 254 AFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
W K +++ + S LT+ V + Y C+A NK G +A++ L
Sbjct: 244 TMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHL 302
Score = 45.4 bits (106), Expect = 8e-05
Identities = 34/142 (23%), Positives = 62/142 (43%), Gaps = 13/142 (9%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCL 161
SL ++++ TD G Y C+ + ++L VQ PK+ T EG V +TC
Sbjct: 369 SLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW-EGNQVNITCE 427
Query: 162 ATGKPEPSISW---RHISPSAK-------PFENGQYLDIYGITRDQAGEYECSAENDVSF 211
P +ISW + PS+ + YL++ + + G Y C+A N +
Sbjct: 428 VFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQ 487
Query: 212 PDVRKVKVVVN--FAPTIQEIK 231
+ + V + +P+I +++
Sbjct: 488 ESLEFILVQADTPSSPSIDQVE 509
Score = 33.9 bits (76), Expect = 0.23
Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 3/76 (3%)
Query: 233 GTVTPGRSGLIRCEGAG-VPPPAFEWYK--GEKKLFNGQQGIIIQNFSTRSILTVTNVTQ 289
G ++ G S C+ AG W+ GEK N Q+ ++ N + S LT+ N
Sbjct: 29 GEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANI 88
Query: 290 EHFGNYTCVAANKLGT 305
+ G Y CV + G+
Sbjct: 89 DDAGIYKCVVTGEDGS 104
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 95.9 bits (237), Expect = 5e-20
Identities = 75/243 (30%), Positives = 108/243 (44%), Gaps = 17/243 (6%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISND----MTVNEGTNVT 157
+LQI V+D G YTC Q + LTV VPP I D ++ + V EGT+V+
Sbjct: 3019 TLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVS 3078
Query: 158 LTCLATGKPEPSISW----RHISPS--AKPFENGQYLDIYGITRDQAGEYECSAENDVSF 211
L C + P P I+W R I+ S + +GQ L I G+Y C A N V+
Sbjct: 3079 LECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAIN-VAG 3137
Query: 212 PDVRKVKVVVNFAPTIQEIKSGTV--TPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQ 269
D + + V P+I+ + + T + C+ G+PPP W K K++ N
Sbjct: 3138 RDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIEN-SD 3196
Query: 270 GIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPSTAQYGITGSA 326
+ ++ S S L + GNYTC+A+N G L+ PPS A I
Sbjct: 3197 SLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDV 3256
Query: 327 DVL 329
VL
Sbjct: 3257 SVL 3259
Score = 94.4 bits (233), Expect = 1e-19
Identities = 69/223 (30%), Positives = 108/223 (48%), Gaps = 16/223 (7%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLA 162
L ++NV + D G YTC T V LTV V P ++ D+++N+G + L+C A
Sbjct: 4224 LILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKA 4283
Query: 163 TGKPEPSISW---RHISPSAKPFENGQY-LDIYGITRDQAGEYECSAENDVSFPDVRKVK 218
TG P P ++W +I P+ NG L I ++++ +G Y C+AEN V F V+ +
Sbjct: 4284 TGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGF--VKAIG 4341
Query: 219 VVVNFAPTI--QEIKSGTVTP-GRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQN 275
V P + + S + P G + ++ CE G P P +W +K + + I+
Sbjct: 4342 FVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQW---NRKGVDIEISHRIRQ 4398
Query: 276 FSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL---NPP 315
S L + E G+YTCVA N+ G S+ L +PP
Sbjct: 4399 LGNGS-LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 92.8 bits (229), Expect = 4e-19
Identities = 72/221 (32%), Positives = 94/221 (42%), Gaps = 15/221 (6%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLA 162
L IQ+ VTD G Y C ++ L V VPP I +MTV TL C A
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEA 3827
Query: 163 TGKPEPSISWR---HI------SPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPD 213
TG P+PSI+WR H+ S + +G L I + D YEC+ N D
Sbjct: 3828 TGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS-LVIISPSVDDTATYECTVTNGAG-DD 3885
Query: 214 VRKVKVVVNFAPTI-QEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGII 272
R V + V P+I E VT +I C +GVP P+ W K +L G
Sbjct: 3886 KRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYR 3945
Query: 273 IQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 313
I + IL H G YTCVA N G+ + + L+
Sbjct: 3946 ILSSGAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLH 3983
Score = 92.4 bits (228), Expect = 5e-19
Identities = 69/240 (28%), Positives = 104/240 (43%), Gaps = 28/240 (11%)
Query: 85 WSVDPRVSISTLNKR---DYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKI 141
W D R + ++ +R SLQI V D G YTC + LTV VPP+I
Sbjct: 4112 WHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRI 4171
Query: 142 YDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISP---------SAKPFENGQYLDIYG 192
TVNE + L C+A G P P+I+W+ + +A+P+ L +
Sbjct: 4172 RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---LILEN 4228
Query: 193 ITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSG-TVTPGRSGLIRCEGAGVP 251
+ + +G Y C A N+ + D V + V+ PT E+ ++ G + C+ G+P
Sbjct: 4229 VVLEDSGFYTCVA-NNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIP 4287
Query: 252 PPAFEWYKGEKKLFNGQQGIIIQNFST---RSILTVTNVTQEHFGNYTCVAANKLGTTNA 308
P W FN II +F + S L + V++E G Y C A N +G A
Sbjct: 4288 LPKLTW------TFN--NNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKA 4339
Score = 92.0 bits (227), Expect = 7e-19
Identities = 72/244 (29%), Positives = 112/244 (45%), Gaps = 27/244 (11%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKI---YDISNDMTVNEGTNVTLT 159
LQ++N+ V+D G Y C + L+V PP I + +++V E +V+LT
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLT 2407
Query: 160 CLATGKPEPSISWRH------ISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPD 213
C A+G P PSI+W +S S + G+ L + T + AG+Y C N +
Sbjct: 2408 CEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAG--E 2465
Query: 214 VRKVKVVVNFAP-------TIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFN 266
RK+ + P T++++K V +S + CE G P P W+K + L
Sbjct: 2466 ERKIFGLSVLVPPHIVGENTLEDVK---VKEKQSVTLTCEVTGNPVPEITWHKDGQPLQE 2522
Query: 267 GQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPSTAQYGIT 323
+ II S L +TNV H G YTC+A++ G + S LN P+ A G
Sbjct: 2523 DEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSD 2579
Query: 324 GSAD 327
G+ +
Sbjct: 2580 GNPE 2583
Score = 91.7 bits (226), Expect = 9e-19
Identities = 79/289 (27%), Positives = 125/289 (43%), Gaps = 19/289 (6%)
Query: 46 DNMMVRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQI 105
+N+ V G+ AVL C + R+ D +P I TL + SL++
Sbjct: 527 NNVTVTPGERAVLTCLIISAVDYNLTWQRND-----RDVRLAEP-ARIRTL--ANLSLEL 578
Query: 106 QNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGK 165
++V D G Y C V ++ V LTVQ PPK+ + + + G+ V++ C ATG
Sbjct: 579 KSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGY 638
Query: 166 PEPSISWR-----HISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVV 220
P+P I+W + + L I AG Y C A N D + +
Sbjct: 639 PKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAG-TDKQNSTLR 697
Query: 221 VNFAPTIQEIKSG-TVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTR 279
AP + ++S V G ++ C+ +G+PPP +W+KG+ +L +II
Sbjct: 698 YIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLEL-RPSTFLIID--PLL 754
Query: 280 SILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPSTAQYGITGSADV 328
+L + G+YTCVA N+ G + L+ S + I ADV
Sbjct: 755 GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVF-IQEPADV 802
Score = 87.8 bits (216), Expect = 1e-17
Identities = 76/287 (26%), Positives = 117/287 (40%), Gaps = 44/287 (15%)
Query: 50 VRKGDTAVLRCYLEDG--ASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQN 107
V +G L C L G + W+ S+++ +P +++ + D SL I+
Sbjct: 901 VIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ-------NPYITV----RSDGSLHIER 949
Query: 108 VDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKPE 167
V + D G YTC + V V P I ++ EG VTL C A+G P+
Sbjct: 950 VQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPK 1009
Query: 168 PSISWRH----ISPSAKPFENGQYLDIYGIT--RDQAGEYECSAENDVSFPDVRKVKVVV 221
PS+ W IS S+ F G +Y ++ +++GEY C+A N + RKV++ V
Sbjct: 1010 PSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAK-RKVQLTV 1068
Query: 222 NFAPTIQEIKSG---------TVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGII 272
P + + G +V G + CE +PPP W K + +
Sbjct: 1069 YVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQ---------L 1119
Query: 273 IQNFSTR------SILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 313
I FS R + +T G Y CVA N G ++ LN
Sbjct: 1120 ISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLN 1166
Score = 85.5 bits (210), Expect = 7e-17
Identities = 66/219 (30%), Positives = 88/219 (40%), Gaps = 18/219 (8%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY--DISNDMTVNEGTNVTLTC 160
LQI +D G YTC L++QVPP + +I +D++V G NV L C
Sbjct: 3209 LQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVC 3268
Query: 161 LATGKPEPSISW-RHISPSA-------KPFENGQYLDIYGITRDQAGEYECSAENDVSFP 212
A G P P I W + P A + NG L+IYG G+Y C A N
Sbjct: 3269 NANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3328
Query: 213 DVRKVKVVVNFAPTIQ----EIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQ 268
D R + V PTI+ E + S I C G PPP W K L
Sbjct: 3329 D-RIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSS 3387
Query: 269 QGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTN 307
I+ + ++ + YTCVA+N+ G N
Sbjct: 3388 H---IRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDN 3423
Score = 85.5 bits (210), Expect = 7e-17
Identities = 73/246 (29%), Positives = 96/246 (39%), Gaps = 20/246 (8%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCL 161
SL I + V D Y C+V V LTVQVPP I D D V + +TC
Sbjct: 3860 SLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCT 3919
Query: 162 ATGKPEPSISWRHISPSAKPFENGQ------YLDIYGITRDQAGEYECSAENDVSFPDVR 215
A+G P PSI W P +G ++I + AG Y C A N R
Sbjct: 3920 ASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAH-R 3978
Query: 216 KVKVVVNFAPTIQEIKSGT-VTPGRSGLIRCEGAGVPPPAFEWYK-GEKKLFNGQQGIII 273
V + V+ P IQ S V L+ CE G P P W K G +G+ ++
Sbjct: 3979 HVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVL 4038
Query: 274 QNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN-------PPSTAQYGITGSA 326
+ L ++ +E G Y CVA N GT + LN P +Y I
Sbjct: 4039 PSGG----LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHLKEYVIAVDK 4094
Query: 327 DVLFSC 332
+ SC
Sbjct: 4095 PITLSC 4100
Score = 84.7 bits (208), Expect = 1e-16
Identities = 79/288 (27%), Positives = 114/288 (39%), Gaps = 28/288 (9%)
Query: 82 GDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKI 141
G++ PRV I + + LQI N D+ D YTC T + LTV VPP I
Sbjct: 3659 GERLQATPRVRILSGGRY---LQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNI 3715
Query: 142 YDISNDMTVNEGTNVTLTCLATGKPEPSISWR---------HISPSAKPFENGQYLDIYG 192
+ + + L C+A G P P I+WR H S ENG +L I
Sbjct: 3716 KGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSI--LENG-FLHIQS 3772
Query: 193 ITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSG-TVTPGRSGLIRCEGAGVP 251
G Y C A N + D R++ + V+ P+I + TV + CE G+P
Sbjct: 3773 AHVTDTGRYLCMATN-AAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIP 3831
Query: 252 PPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLP 311
P+ W K L N Q + L + + + + Y C N G ++
Sbjct: 3832 KPSINWRK-NGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVD 3890
Query: 312 LN---PPSTA----QYGITGSADVLFSCWYLVLTLSSFTSIFYLKNAI 352
L PPS A + +T A + +C + F SI + KN I
Sbjct: 3891 LTVQVPPSIADEPTDFLVTKHAPAVITC---TASGVPFPSIHWTKNGI 3935
Score = 84.0 bits (206), Expect = 2e-16
Identities = 67/231 (29%), Positives = 98/231 (42%), Gaps = 21/231 (9%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKI--YDISNDMTVNEGTNVTLTC 160
L+I++ V D G YTC ++ + VPP I D +TV EG ++L C
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLC 2218
Query: 161 LATGKPEPSISWRHI-SP-------SAKPFENGQYLDIYGITRDQAGEYECSAENDVSFP 212
++G P P++ W+ SP + G+ L I + A Y C A N V+
Sbjct: 2219 ESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASN-VAGT 2277
Query: 213 DVRKVKVVVNFAPTIQEIKSGT----VTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQ 268
++ + V PTI S VT G+S + CE G+PPP W K L +
Sbjct: 2278 AKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAK 2337
Query: 269 QGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPS 316
++ IL + N+ G Y CVA N G T+ L+ PPS
Sbjct: 2338 G---VEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPS 2385
Score = 82.0 bits (201), Expect = 7e-16
Identities = 68/241 (28%), Positives = 99/241 (41%), Gaps = 22/241 (9%)
Query: 81 GGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPK 140
GG VD +S D +L I +D G YTC ++ L VQ PP
Sbjct: 1207 GGSTMLVDGEHHVSN---PDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPT 1263
Query: 141 IYDIS--NDMTVNE---GTNVTLTCLATGKPEPSISWRH-------ISPSAKPFENGQYL 188
+ D+ + T E + C A G P+P+I W H P E+G L
Sbjct: 1264 VEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLL 1323
Query: 189 DIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTI---QEIKSGTVTPGRSGLIRC 245
I +T GEY C A N+ + RK + V+ P I +++ + +V + + C
Sbjct: 1324 VIASVTPYDNGEYICVAVNEAGTTE-RKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFC 1382
Query: 246 EGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGT 305
E G P P WYK ++ + IQ + IL + T E G Y+C A N GT
Sbjct: 1383 EVEGTPSPIIMWYKDNVQV---TESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGT 1439
Query: 306 T 306
+
Sbjct: 1440 S 1440
Score = 82.0 bits (201), Expect = 7e-16
Identities = 65/229 (28%), Positives = 94/229 (41%), Gaps = 19/229 (8%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKI----YDISNDMTVNEGTNVTL 158
LQI V D G YTC + ++Q + V VPP I D+ ++TV + +
Sbjct: 2833 LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALI 2892
Query: 159 TCLATGKPEPSISWRHISPSA------KPFENGQYLDIYGITRDQAGEYECSAENDVSFP 212
CL++G P P SW+ K NG+ L I G Y C AEN
Sbjct: 2893 ECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSA 2952
Query: 213 DVRKVKVVVNFAPTIQEIKSGTVTPGRSGLI--RCEGAGVPPPAFEWYKGEKKLFNGQQG 270
+ + V+ P++ KS +T + I CE +G PPP W K E+ +
Sbjct: 2953 K-KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNT 3011
Query: 271 IIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPS 316
+I+ T L + G YTC+A N+ G + L PPS
Sbjct: 3012 LIVPGGRT---LQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPS 3057
Score = 81.6 bits (200), Expect = 1e-15
Identities = 67/236 (28%), Positives = 96/236 (40%), Gaps = 19/236 (8%)
Query: 83 DKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY 142
D W V S+ L+ L++ + D G YTC V+ L+V VPP I
Sbjct: 2423 DGWPVSLSNSVRILSG-GRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIV 2481
Query: 143 --DISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFE------NGQYLDIYGIT 194
+ D+ V E +VTLTC TG P P I+W + E G++L I +
Sbjct: 2482 GENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQ 2541
Query: 195 RDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSG------TVTPGRSGLIRCEGA 248
G Y C A + R + V +PTI + S TV + CE
Sbjct: 2542 VPHTGRYTCLASSPAGHKS-RSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAY 2600
Query: 249 GVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 304
PP W+K L + + I+ T IL N +++ G Y+CVA N+ G
Sbjct: 2601 SYPPATITWFKDGTPLESNRNIRILPGGRTLQIL---NAQEDNAGRYSCVATNEAG 2653
Score = 80.9 bits (198), Expect = 2e-15
Identities = 62/219 (28%), Positives = 92/219 (42%), Gaps = 19/219 (8%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCL 161
S++I +D G Y C T V L V VPPKI + V G V + C
Sbjct: 1134 SMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCN 1193
Query: 162 ATGKPEPSISWRHISPSAKPFENGQY--------LDIYGITRDQAGEYECSAENDVSFPD 213
A G P P I+W + +G++ L I T AG Y C A N ++ D
Sbjct: 1194 AQGTPLPVITWS--KGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATN-IAGTD 1250
Query: 214 VRKVKVVVNFAPTIQEIKSGTVTPGRSGLIR------CEGAGVPPPAFEWYKGEKKLFNG 267
++ + V PT+++++ T + + C G P P +W ++L
Sbjct: 1251 ETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGR 1310
Query: 268 QQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTT 306
+ GI I T +L + +VT G Y CVA N+ GTT
Sbjct: 1311 EPGISILEDGT--LLVIASVTPYDNGEYICVAVNEAGTT 1347
Score = 80.1 bits (196), Expect = 3e-15
Identities = 76/291 (26%), Positives = 117/291 (40%), Gaps = 30/291 (10%)
Query: 46 DNMMVRKGDTAVLRCYLEDG--ASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSL 103
+ + V KG + + C + DG A AWL G +D +++ST L
Sbjct: 3443 EEITVLKGSSTSMAC-ITDGTPAPSMAWLR-------DGQPLGLDAHLTVST---HGMVL 3491
Query: 104 QIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKI--YDISNDMTVNEGTNVTLTCL 161
Q+ + D G YTC + + L V PP I + +++V + LTC+
Sbjct: 3492 QLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELTCI 3551
Query: 162 ATGKPEPSISWRH------ISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPD-- 213
A+G P P ++W + + G+ L I + G Y C A + D
Sbjct: 3552 ASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKE 3611
Query: 214 -VRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGII 272
+ +V V N A T E + TV R + C+ VPPP W + ++L Q
Sbjct: 3612 YLVRVHVPPNIAGT-DEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERL---QATPR 3667
Query: 273 IQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNAS--LPLNPPSTAQYG 321
++ S L + N NYTCVA+N G T L +N P + G
Sbjct: 3668 VRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGG 3718
Score = 79.0 bits (193), Expect = 6e-15
Identities = 67/250 (26%), Positives = 97/250 (38%), Gaps = 23/250 (9%)
Query: 75 SSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLT 134
S II D V +I T+N L++ D G Y+C ++
Sbjct: 1389 SPIIMWYKDNVQVTESSTIQTVNNGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFNID 1447
Query: 135 VQVPPKIY--DISNDMTVNEGTNVTLTCLATGKPEPSISWRHIS-------PSAKPFENG 185
V VPP I + N+++V +V L C G P P I W P+ + + G
Sbjct: 1448 VLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG 1507
Query: 186 QYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIR- 244
Q L + R+ G Y+C+ N + +K+ + P+I K G VT S LI
Sbjct: 1508 QVLHLKNARRNDKGRYQCTVSNAAG-KQAKDIKLTIYIPPSI---KGGNVTTDISVLINS 1563
Query: 245 -----CEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVA 299
CE G+P PA WYK + + + Q + I L + YTC
Sbjct: 1564 LIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDK---GQYLHIPRAQVSDSATYTCHV 1620
Query: 300 ANKLGTTNAS 309
AN GT S
Sbjct: 1621 ANVAGTAEKS 1630
Score = 78.6 bits (192), Expect = 8e-15
Identities = 77/292 (26%), Positives = 116/292 (39%), Gaps = 36/292 (12%)
Query: 53 GDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTD 112
G+ + + +L+DG A N + I AGG K L+I + D
Sbjct: 1667 GNPSPILTWLKDGVPVKA--NDNIRIEAGGKK------------------LEIMSAQEID 1706
Query: 113 DGPYTCSVQTQHTPRTMQVHLTVQVPPKIY--DISNDMTVNEGTNVTLTCLATGKPEPSI 170
G Y C + + ++ + V VPP I D ++ V + L C TG P P+I
Sbjct: 1707 RGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTI 1766
Query: 171 SWRHISP------SAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFA 224
W K NG+ L I G Y C A N ++ +V V+
Sbjct: 1767 MWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAG-DHKKEFEVTVHVP 1825
Query: 225 PTIQE--IKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSIL 282
PTI+ + V + ++C G+P P+ W K ++ + Q + IQ S+ +L
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQ--SSGRVL 1883
Query: 283 TVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPSTAQYGITGSADVLFS 331
+ E G YTCVA N G T + L+ PPS G + VL S
Sbjct: 1884 QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVS 1935
Score = 78.6 bits (192), Expect = 8e-15
Identities = 65/229 (28%), Positives = 92/229 (40%), Gaps = 18/229 (7%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY--DISNDMTVNEGTNVTLTC 160
L+I V D G YTC + + + V VPP I D D+TV VTL C
Sbjct: 3584 LRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLEC 3643
Query: 161 LATGKPEPSISW------RHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDV 214
+ P P I+W +P + G+YL I Y C A N ++
Sbjct: 3644 KSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASN-IAGKTT 3702
Query: 215 RKVKVVVNFAPTIQ-EIKSGTVTPGRSGLIRCEGAGVPPPAFEWYK-GEKKLFNGQQGII 272
R+ + VN P I+ +S + +S ++ C GVP P W K G N + I
Sbjct: 3703 REFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSI 3762
Query: 273 IQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPSTA 318
++N L + + G Y C+A N GT + L PPS A
Sbjct: 3763 LEN----GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIA 3807
Score = 78.2 bits (191), Expect = 1e-14
Identities = 64/223 (28%), Positives = 92/223 (41%), Gaps = 14/223 (6%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTN-VTLTCL 161
L I+ +V+D G Y C HL V VPP I ++ V +N VTLTC
Sbjct: 3115 LHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCD 3174
Query: 162 ATGKPEPSISW--------RHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPD 213
ATG P P+I+W S + G L I +G Y C A N +
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN-MEGKA 3233
Query: 214 VRKVKVVVNFAPTIQ--EIKSG-TVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQG 270
+ + + P++ EI S +V G + + C G+P P +W K K + +G+
Sbjct: 3234 QKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETE 3293
Query: 271 IIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 313
I + + S L + G YTCVA N G + LN
Sbjct: 3294 RIRVS-ANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLN 3335
Score = 77.4 bits (189), Expect = 2e-14
Identities = 65/217 (29%), Positives = 88/217 (40%), Gaps = 12/217 (5%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLA 162
LQI D G Y C Q ++ L VQVPP I + + +TL+C A
Sbjct: 4043 LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEA 4102
Query: 163 TGKPEPSISW----RHISPSAKP--FENGQYLDIYGITRDQAGEYECSAENDVSFPDVRK 216
G P P I+W R I S + +G L I + AG Y C A N V+
Sbjct: 4103 DGLPPPDITWHKDGRAIVESIRQRVLSSGS-LQIAFVQPGDAGHYTCMAAN-VAGSSSTS 4160
Query: 217 VKVVVNFAPTIQEIKSG-TVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQN 275
K+ V+ P I+ + TV ++ C G+P PA W K L N +
Sbjct: 4161 TKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEP 4220
Query: 276 FSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
+ L + NV E G YTCVA N G ++ L
Sbjct: 4221 YGE---LILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254
Score = 77.0 bits (188), Expect = 2e-14
Identities = 71/266 (26%), Positives = 105/266 (39%), Gaps = 37/266 (13%)
Query: 79 FAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVP 138
+ G D V+I+ ++LQI+ ++D G YTC + + +QVP
Sbjct: 2709 YKDGQPLKSDDHVNIAA---NGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVP 2765
Query: 139 P---KIYDISN-----------DMTVNEGTNVTLTCLATGKPEPSISW----RHISPSAK 180
P K+++I N D+ +N ++L C P P+++W ++ S K
Sbjct: 2766 PSFQKLWEIGNMLDTGRNGEAKDVIIN--NPISLYCETNAAPPPTLTWYKDGHPLTSSDK 2823
Query: 181 P--FENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSG----- 233
G+ L I + AG Y C A N+ D + V V P I+ S
Sbjct: 2824 VLILPGGRVLQIPRAKVEDAGRYTCVAVNEAG-EDSLQYDVRVLVPPIIKGANSDLPEEV 2882
Query: 234 TVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFG 293
TV +S LI C +G P P W K + L + N IL + N G
Sbjct: 2883 TVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSN---GRILQILNTQITDIG 2939
Query: 294 NYTCVAANKLGTTNASLPLN---PPS 316
Y CVA N G+ LN PPS
Sbjct: 2940 RYVCVAENTAGSAKKYFNLNVHVPPS 2965
Score = 76.6 bits (187), Expect = 3e-14
Identities = 70/234 (29%), Positives = 94/234 (40%), Gaps = 19/234 (8%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLA 162
L+IQ D G YTC + T ++ L V PP D+++ G+NVTL C
Sbjct: 757 LKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYV 816
Query: 163 TGKPEPSISWRHISPS---AKPFENGQY-------LDIYGITRDQAGEYECSAENDV-SF 211
G PEP+I WR + ++PF L I + G Y C AEN
Sbjct: 817 QGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKI 876
Query: 212 PDVRKVKVVVNFAPTIQEIKS-GTVTPGRSGLIRCE-GAGVPPPAFEWYKGEKKLFNGQQ 269
V V AP I S V G+ + C AG P P W K L
Sbjct: 877 QSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPY 936
Query: 270 GIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTN--ASLPLNPPSTAQYG 321
+ + S L + V + G YTCVA+N GT N S+ ++ T Q+G
Sbjct: 937 ITVRSDGS----LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHG 986
Score = 74.7 bits (182), Expect = 1e-13
Identities = 70/248 (28%), Positives = 104/248 (41%), Gaps = 21/248 (8%)
Query: 85 WSVDPRV-----SISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPP 139
W D R+ S++ LN R + I++ ++D G Y C + L V V P
Sbjct: 1954 WYKDNRLLSGSTSMTFLN-RGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAP 2012
Query: 140 KIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENG-QYLD---IYGITR 195
I +N + V V L C A G P PS++W F NG Q L I +T
Sbjct: 2013 SISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTS 2072
Query: 196 DQ---AGEYECSAENDVSFPDVRKVKVVVNFAPTIQ-EIKSGTVTPGRSGLIRCEGAGVP 251
Q G Y C A N + R + + V P I E ++ +V ++ + C+ +P
Sbjct: 2073 AQISDTGRYTCVAVN-AAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIP 2131
Query: 252 PPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLP 311
PP W K L + G+ I RS+L + + + G YTC A N G T +
Sbjct: 2132 PPTLTWLKDGHPLLK-KPGLSIS--ENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYN 2188
Query: 312 LN---PPS 316
+N PP+
Sbjct: 2189 VNIWVPPN 2196
Score = 72.4 bits (176), Expect = 6e-13
Identities = 57/215 (26%), Positives = 90/215 (41%), Gaps = 15/215 (6%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDIS-NDMTVNEGTNVTLTCL 161
L I V++ G Y C + +TV VPP I ++ V + V L C+
Sbjct: 1790 LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCI 1849
Query: 162 ATGKPEPSISW-------RHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDV 214
A G P PSI+W + K +G+ L I + AG Y C A N
Sbjct: 1850 ANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQ- 1908
Query: 215 RKVKVVVNFAPTIQE---IKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGI 271
+ +++ V+ P++++ + + TV + C+ AG P P WYK + +L +G +
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYK-DNRLLSGSTSM 1967
Query: 272 IIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTT 306
N I+ + + G Y CVA N G T
Sbjct: 1968 TFLN--RGQIIDIESAQISDAGIYKCVAINSAGAT 2000
Score = 70.1 bits (170), Expect = 3e-12
Identities = 63/237 (26%), Positives = 90/237 (37%), Gaps = 27/237 (11%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISND-----MTVNEGTNVT 157
LQI NV V G YTC + ++ L V V P I + +D +TV + +
Sbjct: 2535 LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTS 2594
Query: 158 LTCLATGKPEPSISWRHISPSAKPFEN------GQYLDIYGITRDQAGEYECSAENDVSF 211
L C A P +I+W + N G+ L I D AG Y C A N+
Sbjct: 2595 LVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG- 2653
Query: 212 PDVRKVKVVVNFAPTIQE---------IKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEK 262
++ +V V P I + K + + + CE +P + WYK +
Sbjct: 2654 EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ 2713
Query: 263 KLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPS 316
L + I N T L + G YTCVA+N G +N PPS
Sbjct: 2714 PLKSDDHVNIAANGHT---LQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPS 2767
Score = 69.3 bits (168), Expect = 5e-12
Identities = 48/212 (22%), Positives = 84/212 (39%), Gaps = 13/212 (6%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCL 161
+L I V ++D+G Y C + Q V PP + + N++TV G LTCL
Sbjct: 483 NLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCL 542
Query: 162 ATGKPEPSISWRHISPSAKPFENGQY-------LDIYGITRDQAGEYECSAENDVSFPDV 214
+ +++W+ + E + L++ + + AGEY C ++
Sbjct: 543 IISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSE-GGSSA 601
Query: 215 RKVKVVVNFAPTIQEI-KSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIII 273
V + V P + + K+ + T G I C G P P W + + +
Sbjct: 602 ASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHR---- 657
Query: 274 QNFSTRSILTVTNVTQEHFGNYTCVAANKLGT 305
++ L + N + G Y C+A+N GT
Sbjct: 658 YRMTSDGTLFIKNAAPKDAGIYGCLASNSAGT 689
Score = 68.6 bits (166), Expect = 8e-12
Identities = 54/218 (24%), Positives = 87/218 (39%), Gaps = 14/218 (6%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY-DISNDMTVNEGTNVTLTCL 161
L I+ V D G Y C+ + + V+ PP D ++ G N L C
Sbjct: 4313 LVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCE 4372
Query: 162 ATGKPEPSISWRH------ISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVR 215
G P P+I W IS + NG L IYG + AG+Y C A N+ + R
Sbjct: 4373 VKGDPTPTIQWNRKGVDIEISHRIRQLGNGS-LAIYGTVNEDAGDYTCVATNEAGVVE-R 4430
Query: 216 KVKVVVNFAPTIQ-EIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQ 274
+ + + P I E + G ++ C+ G P P W + + + ++
Sbjct: 4431 SMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLS 4490
Query: 275 NFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
N S L + + +E + CVA N +G+ +P+
Sbjct: 4491 NNS----LYIADAQKEDTSEFECVARNLMGSVLVRVPV 4524
Score = 67.0 bits (162), Expect = 2e-11
Identities = 50/218 (22%), Positives = 93/218 (42%), Gaps = 25/218 (11%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDI--SNDMTVNEGTNVTLTC 160
++I V+D YTC + +L V PP + + + ++TV +G++ ++ C
Sbjct: 3398 IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMAC 3457
Query: 161 LATGKPEPSISW----------RHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVS 210
+ G P PS++W H++ S +G L + + +G+Y C A N+
Sbjct: 3458 ITDGTPAPSMAWLRDGQPLGLDAHLTVST----HGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 211 FPDVRKVKVVVNFAPT----IQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFN 266
+V K ++ P +E + +V + C +G+P P W K + L
Sbjct: 3514 --EVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQ 3571
Query: 267 GQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 304
Q +Q +L ++ E G YTC+A++ G
Sbjct: 3572 TDQ---VQTLGGGEVLRISTAQVEDTGRYTCLASSPAG 3606
Score = 63.9 bits (154), Expect = 2e-10
Identities = 56/230 (24%), Positives = 84/230 (36%), Gaps = 31/230 (13%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYD--------ISNDMTVNEG 153
+LQI N + G Y+C + + V +PP I ++ +
Sbjct: 2630 TLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVN 2689
Query: 154 TNVTLTCLATGKPEPSISWRHISPSAKPFE------NGQYLDIYGITRDQAGEYECSAEN 207
+TL C A P S+SW K + NG L I G Y C A N
Sbjct: 2690 NTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASN 2749
Query: 208 DVSFPDVRKVKVVVNFAPTIQEI--KSGTVTPGRSG-----------LIRCEGAGVPPPA 254
++ D V + P+ Q++ + GR+G + CE PPP
Sbjct: 2750 -IAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPT 2808
Query: 255 FEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 304
WYK L + + +I+ +L + E G YTCVA N+ G
Sbjct: 2809 LTWYKDGHPLTSSDKVLILPG---GRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 62.8 bits (151), Expect = 5e-10
Identities = 62/243 (25%), Positives = 98/243 (40%), Gaps = 20/243 (8%)
Query: 96 LNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY-DISNDMT--VNE 152
++K Y L I V+D YTC V H+ V VPP I +++ + V
Sbjct: 1597 IDKGQY-LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVI 1655
Query: 153 GTNVTLTCLATGKPEPSISWRHISPSAKPFEN------GQYLDIYGITRDQAGEYECSAE 206
++TL C A G P P ++W K +N G+ L+I G+Y C A
Sbjct: 1656 AHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVAT 1715
Query: 207 NDVSFPDVRKVKVVVNFAPTIQ---EIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKK 263
+ ++ K +V V P I+ E V + C G PPP W K + +
Sbjct: 1716 SVAGEKEI-KYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLK-DGQ 1773
Query: 264 LFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPSTAQY 320
L + + G I + ++ V+ + G Y C+AAN G + PP+
Sbjct: 1774 LIDERDGFKILLNGRKLVIAQAQVS--NTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSS 1831
Query: 321 GIT 323
G++
Sbjct: 1832 GLS 1834
Score = 60.8 bits (146), Expect = 2e-09
Identities = 68/239 (28%), Positives = 97/239 (40%), Gaps = 30/239 (12%)
Query: 92 SISTLNK-RDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQ--VPPKIYDISNDM 148
S+S++++ R +L I N+ +D G Y C + Q + +TV V P I +
Sbjct: 840 SVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVA 899
Query: 149 TVNEGTNVTLTC-LATGKPEPSISWRHISPSAKPFENGQY-------LDIYGITRDQAGE 200
V EG +TL C L G P P W I SA +N L I + GE
Sbjct: 900 NVIEGQQLTLPCTLLAGNPIPERRW--IKNSAMLLQNPYITVRSDGSLHIERVQLQDGGE 957
Query: 201 YECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVT-PGRSGLIRCEGAGVPPPAFEWYK 259
Y C A N V+ + + VVV+ PTIQ + T G + C+ +G P P+ W K
Sbjct: 958 YTCVASN-VAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSK 1016
Query: 260 GEKKLFNGQQGIIIQNFSTR------SILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
+G +I S + L V + E G Y C A N G + L
Sbjct: 1017 ---------KGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQL 1066
Score = 59.7 bits (143), Expect = 4e-09
Identities = 58/217 (26%), Positives = 83/217 (38%), Gaps = 20/217 (9%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKI---YDISNDMTVNEGTNVTL 158
+L I +D G YTC +L V V P I D + + T++ +
Sbjct: 3303 TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI 3362
Query: 159 TCLATGKPEPSISWRH------ISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFP 212
C ATG P P I+W +S + GQ + I Y C A N
Sbjct: 3363 ECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGV- 3421
Query: 213 DVRKVKVVVNFAPTIQEIKSG----TVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQ 268
D + + V FAP + G TV G S + C G P P+ W + + L G
Sbjct: 3422 DNKHYNLQV-FAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPL--GL 3478
Query: 269 QGIIIQNFSTRS-ILTVTNVTQEHFGNYTCVAANKLG 304
+ ST +L + E G YTC+A+N+ G
Sbjct: 3479 DAHL--TVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Score = 53.5 bits (127), Expect = 3e-07
Identities = 45/174 (25%), Positives = 68/174 (39%), Gaps = 19/174 (10%)
Query: 39 DFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNK 98
D+P N + G A+L C ++ + NR VD +S
Sbjct: 4354 DYP----SNWIEPLGGNAILNCEVKGDPTPTIQWNRKG----------VDIEISHRIRQL 4399
Query: 99 RDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTL 158
+ SL I D G YTC + + LT+Q PP I + +N G + L
Sbjct: 4400 GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIIL 4459
Query: 159 TCLATGKPEPSISWRHISPSAKPFE-----NGQYLDIYGITRDQAGEYECSAEN 207
C ATG+P+P+I+W S + + L I ++ E+EC A N
Sbjct: 4460 NCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARN 4513
>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
[Homo sapiens]
Length = 1093
Score = 95.9 bits (237), Expect = 5e-20
Identities = 63/222 (28%), Positives = 99/222 (44%), Gaps = 15/222 (6%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTM--QVHLTVQVPPKIYDISNDMTVNEGTNVTLTC 160
L ++ V +G Y C + T H T + LTV V P +D+T+ T L C
Sbjct: 562 LHLRQVTFGHEGRYQCVI-TNHFGSTYSHKARLTVNVLPSFTKTPHDITIRTTTMARLEC 620
Query: 161 LATGKPEPSISWRHISPSAKPFENGQYL------DIYGITR---DQAGEYECSAENDVSF 211
ATG P P I+W+ + P + + D++ IT D AG Y C+A+N
Sbjct: 621 AATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQNSAGS 680
Query: 212 PDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGI 271
V+ + ++ V+ G + ++C+ G PPP W+KG++ L ++
Sbjct: 681 ISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHH 740
Query: 272 IIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 313
+ + +L V NV E G YTC +N LGT A L+
Sbjct: 741 LTPD---NQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLS 779
Score = 28.9 bits (63), Expect = 7.3
Identities = 18/62 (29%), Positives = 24/62 (38%), Gaps = 7/62 (11%)
Query: 252 PPAFEWYKGEKKLFNGQQGIII-------QNFSTRSILTVTNVTQEHFGNYTCVAANKLG 304
P F W K + L N + + +IL + VT H G Y CV N G
Sbjct: 525 PMTFAWKKDNEVLTNADMENFVHVHAQDGEVMEYTTILHLRQVTFGHEGRYQCVITNHFG 584
Query: 305 TT 306
+T
Sbjct: 585 ST 586
>gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo
sapiens]
Length = 858
Score = 94.0 bits (232), Expect = 2e-19
Identities = 68/226 (30%), Positives = 99/226 (43%), Gaps = 25/226 (11%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLA 162
L I+ VD D+ Y C + + + +HL V PKI + N + VTLTC A
Sbjct: 272 LTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEA 331
Query: 163 TGKPEPSISW----RHISPSAKPF----ENGQYLDIYGITRD---------------QAG 199
+G P PSI+W R+IS K E + LD + + R AG
Sbjct: 332 SGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAG 391
Query: 200 EYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYK 259
EY C+A N + D + + + V +AP +Q + G I CE P W++
Sbjct: 392 EYICTASNTIG-QDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFR 450
Query: 260 -GEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 304
G+ + I I N + S L VT ++ FGNY C A N++G
Sbjct: 451 DGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIG 496
Score = 77.4 bits (189), Expect = 2e-14
Identities = 62/239 (25%), Positives = 100/239 (41%), Gaps = 20/239 (8%)
Query: 90 RVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY--DISND 147
R+S+ + +L I N ++ D G Y C V T + + V++ K+ +
Sbjct: 68 RISVVWNDDSSSTLTIYNANIDDAGIYKC-VVTGEDGSESEATVNVKIFQKLMFKNAPTP 126
Query: 148 MTVNEGTNVTLTCLATGKPEPSISWRH-----ISPSAKPF--ENGQYLDIYGITRDQAGE 200
EG + + C P+I W+H I F + YL I GI + G
Sbjct: 127 QEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGT 186
Query: 201 YECS----AENDVSFPDVRKVKVVVNFAPTI---QEIKSGTVTPGRSGLIRCEGAGVPPP 253
Y C A +++F D ++V+VN PTI Q I + T G+S + C+ G P P
Sbjct: 187 YRCEGRILARGEINFKD---IQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEP 243
Query: 254 AFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
W K +++ + S LT+ V + Y C+A NK G +A++ L
Sbjct: 244 TMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHL 302
Score = 76.6 bits (187), Expect = 3e-14
Identities = 59/238 (24%), Positives = 103/238 (43%), Gaps = 29/238 (12%)
Query: 103 LQIQNVDVTDDGPYTCS--VQTQHTPRTMQVHLTVQVPPKIYDISN--DMTVNEGTNVTL 158
LQI+ + TD+G Y C + + + + V VPP I N + T N G +VTL
Sbjct: 174 LQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTL 233
Query: 159 TCLATGKPEPSISWRHISPSAKPFENGQ---------YLDIYGITRDQAGEYECSAENDV 209
C A G PEP++SW + E+ + L I + ++ EY C AEN
Sbjct: 234 VCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKA 293
Query: 210 SFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGL-IRCEGAGVPPPAFEWYKGEKKLFNGQ 268
D + + V P I +++ T + + CE +G P P+ W + + + +
Sbjct: 294 GEQDA-TIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEE 352
Query: 269 QG--------------IIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
+ +++++ + S LT+ ++ G Y C A+N +G + S+ L
Sbjct: 353 KASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYL 410
Score = 45.4 bits (106), Expect = 8e-05
Identities = 34/142 (23%), Positives = 62/142 (43%), Gaps = 13/142 (9%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCL 161
SL ++++ TD G Y C+ + ++L VQ PK+ T EG V +TC
Sbjct: 379 SLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW-EGNQVNITCE 437
Query: 162 ATGKPEPSISW---RHISPSAK-------PFENGQYLDIYGITRDQAGEYECSAENDVSF 211
P +ISW + PS+ + YL++ + + G Y C+A N +
Sbjct: 438 VFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQ 497
Query: 212 PDVRKVKVVVN--FAPTIQEIK 231
+ + V + +P+I +++
Sbjct: 498 ESLEFILVQADTPSSPSIDQVE 519
Score = 33.9 bits (76), Expect = 0.23
Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 3/76 (3%)
Query: 233 GTVTPGRSGLIRCEGAG-VPPPAFEWYK--GEKKLFNGQQGIIIQNFSTRSILTVTNVTQ 289
G ++ G S C+ AG W+ GEK N Q+ ++ N + S LT+ N
Sbjct: 29 GEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANI 88
Query: 290 EHFGNYTCVAANKLGT 305
+ G Y CV + G+
Sbjct: 89 DDAGIYKCVVTGEDGS 104
>gi|7662320 leucine-rich repeats and immunoglobulin-like domains 2
[Homo sapiens]
Length = 1065
Score = 89.0 bits (219), Expect = 6e-18
Identities = 60/222 (27%), Positives = 94/222 (42%), Gaps = 15/222 (6%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQH--TPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTC 160
L + NV+ TD+G Y C V T H + + + LTV P D+T+ G L C
Sbjct: 565 LHLFNVNFTDEGKYQCIV-TNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGAMARLEC 623
Query: 161 LATGKPEPSISWRHISPSAKPFENGQYL------DIYGITR---DQAGEYECSAENDVSF 211
A G P P ISW+ + P + + D++ I + G Y C A+N
Sbjct: 624 AAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNTAGG 683
Query: 212 PDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGI 271
V+ I+ ++ TVT G + +++C G P P W K + L ++
Sbjct: 684 LSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHF 743
Query: 272 IIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 313
+ +L + + E G YTC+ +N LGT + LN
Sbjct: 744 FA---AANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLN 782
Score = 57.0 bits (136), Expect = 3e-08
Identities = 50/200 (25%), Positives = 74/200 (37%), Gaps = 22/200 (11%)
Query: 139 PKIYDISNDMTVNEGTNVTLTCLATGKPEPSIS--WRHIS----------------PSAK 180
P+I + G NVTLTC A + +S WR S + +
Sbjct: 498 PQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSEILYDVDTENFVRYWQQAGE 557
Query: 181 PFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSG-TVTPGR 239
E L ++ + G+Y+C N +K K+ VN P+ + T+ G
Sbjct: 558 ALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGA 617
Query: 240 SGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVA 299
+ C G P P W K F + + + + NV E G Y+C+A
Sbjct: 618 MARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMA 677
Query: 300 ANKLG--TTNASLP-LNPPS 316
N G + NASL L PS
Sbjct: 678 QNTAGGLSANASLTVLETPS 697
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 88.6 bits (218), Expect = 8e-18
Identities = 64/234 (27%), Positives = 102/234 (43%), Gaps = 13/234 (5%)
Query: 92 SISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVN 151
S + L K L+I NV + D G Y C + + + L V P + ND ++
Sbjct: 343 SKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLD 402
Query: 152 EGTNVTLTCLATGKPEPSISWRH----ISPSAKPFENGQYLDIYGITRDQAGEYECSAEN 207
G+ + C ATGKP P+ W +SP ++ L I+ + + AG Y+C AEN
Sbjct: 403 SGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQCLAEN 462
Query: 208 DVSFPDVRKVKVVVNFAPTI---QEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKL 264
++ APT Q K+ VT + +I C+ G P P W KG++ +
Sbjct: 463 KYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAV 522
Query: 265 FNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTN--ASLPLNPPS 316
++ I+ + S R + N ++ G Y C N G+ ASL + P+
Sbjct: 523 RENKRIAILPDGSLR----ILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPT 572
Score = 81.6 bits (200), Expect = 1e-15
Identities = 65/232 (28%), Positives = 93/232 (40%), Gaps = 32/232 (13%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISND-------------- 147
+L I V +D G Y C V+ T + V PP + ND
Sbjct: 253 NLYISKVQTSDVGSYICLVKNTVT------NARVLSPPTPLTLRNDGVMGEYEPKIEVHF 306
Query: 148 ---MTVNEGTNVTLTCLATGKPEPSISWRHIS---PSAKPFENGQ-YLDIYGITRDQAGE 200
+T +GT V + C A G P P+I+W ++ PS Q L+I + D AG
Sbjct: 307 PFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQAVLEIPNVQLDDAGI 366
Query: 201 YECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKG 260
YEC AEN R V + ++++ + G C+ G P P + W K
Sbjct: 367 YECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKN 426
Query: 261 EKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
L + Q + + N +L + NV Q G Y C+A NK G AS L
Sbjct: 427 GVPL-SPQSRVEMVN----GVLMIHNVNQSDAGMYQCLAENKYGAIYASAEL 473
Score = 34.3 bits (77), Expect = 0.17
Identities = 49/230 (21%), Positives = 78/230 (33%), Gaps = 30/230 (13%)
Query: 116 YTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDM---TVNEGTNVTLTCLATGKPEPSISW 172
Y + H+ + +V P +D+ T ++ V L C G P PS W
Sbjct: 76 YYSPINLYHSSDAFKQDESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRW 135
Query: 173 RHISPSAKPFENGQYLDIYGI-------TRDQAGEYECSAENDVSFPDVRKVKVVVNFAP 225
+ +Y I G +G Y+C A N V +++
Sbjct: 136 LRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQCLATNTVG--------SILSREA 187
Query: 226 TIQEIKSGTVT-PGRSGLIRCEGAGV-----PPP-----AFEWYKGEKKLFNGQQGIIIQ 274
T+Q G + RS + EG GV PPP + W E F +
Sbjct: 188 TLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFI 247
Query: 275 NFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPSTAQYGITG 324
+ T + L ++ V G+Y C+ N + P P + G+ G
Sbjct: 248 SQETGN-LYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMG 296
Score = 30.0 bits (66), Expect = 3.3
Identities = 17/63 (26%), Positives = 28/63 (44%)
Query: 100 DYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLT 159
D SL+I N +D+G Y C + + L+V+ P +I + G ++ L
Sbjct: 533 DGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLN 592
Query: 160 CLA 162
C A
Sbjct: 593 CKA 595
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 88.6 bits (218), Expect = 8e-18
Identities = 64/234 (27%), Positives = 102/234 (43%), Gaps = 13/234 (5%)
Query: 92 SISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVN 151
S + L K L+I NV + D G Y C + + + L V P + ND ++
Sbjct: 269 SKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLD 328
Query: 152 EGTNVTLTCLATGKPEPSISWRH----ISPSAKPFENGQYLDIYGITRDQAGEYECSAEN 207
G+ + C ATGKP P+ W +SP ++ L I+ + + AG Y+C AEN
Sbjct: 329 SGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQCLAEN 388
Query: 208 DVSFPDVRKVKVVVNFAPTI---QEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKL 264
++ APT Q K+ VT + +I C+ G P P W KG++ +
Sbjct: 389 KYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAV 448
Query: 265 FNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTN--ASLPLNPPS 316
++ I+ + S R + N ++ G Y C N G+ ASL + P+
Sbjct: 449 RENKRIAILPDGSLR----ILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPT 498
Score = 81.6 bits (200), Expect = 1e-15
Identities = 65/232 (28%), Positives = 93/232 (40%), Gaps = 32/232 (13%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISND-------------- 147
+L I V +D G Y C V+ T + V PP + ND
Sbjct: 179 NLYISKVQTSDVGSYICLVKNTVT------NARVLSPPTPLTLRNDGVMGEYEPKIEVHF 232
Query: 148 ---MTVNEGTNVTLTCLATGKPEPSISWRHIS---PSAKPFENGQ-YLDIYGITRDQAGE 200
+T +GT V + C A G P P+I+W ++ PS Q L+I + D AG
Sbjct: 233 PFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQAVLEIPNVQLDDAGI 292
Query: 201 YECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKG 260
YEC AEN R V + ++++ + G C+ G P P + W K
Sbjct: 293 YECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKN 352
Query: 261 EKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
L + Q + + N +L + NV Q G Y C+A NK G AS L
Sbjct: 353 GVPL-SPQSRVEMVN----GVLMIHNVNQSDAGMYQCLAENKYGAIYASAEL 399
Score = 33.9 bits (76), Expect = 0.23
Identities = 44/194 (22%), Positives = 67/194 (34%), Gaps = 27/194 (13%)
Query: 149 TVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGI-------TRDQAGEY 201
T ++ V L C G P PS W + +Y I G +G Y
Sbjct: 38 TDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHY 97
Query: 202 ECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVT-PGRSGLIRCEGAGV-----PPP-- 253
+C A N V +++ T+Q G + RS + EG GV PPP
Sbjct: 98 QCLATNTVG--------SILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHS 149
Query: 254 ---AFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASL 310
+ W E F + + T + L ++ V G+Y C+ N +
Sbjct: 150 PEIIYSWVFNEFPSFVAEDSRRFISQETGN-LYISKVQTSDVGSYICLVKNTVTNARVLS 208
Query: 311 PLNPPSTAQYGITG 324
P P + G+ G
Sbjct: 209 PPTPLTLRNDGVMG 222
Score = 30.0 bits (66), Expect = 3.3
Identities = 17/63 (26%), Positives = 28/63 (44%)
Query: 100 DYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLT 159
D SL+I N +D+G Y C + + L+V+ P +I + G ++ L
Sbjct: 459 DGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLN 518
Query: 160 CLA 162
C A
Sbjct: 519 CKA 521
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 87.0 bits (214), Expect = 2e-17
Identities = 78/251 (31%), Positives = 102/251 (40%), Gaps = 31/251 (12%)
Query: 87 VDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISN 146
VDPRV+I+ L IQNV D G Y CS + VQ P+
Sbjct: 385 VDPRVNITPSG----GLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQ 440
Query: 147 DMTVNEGTNVTLTCLATGKPEPSISW-----------RHISPSAKPFENGQYLDIYGITR 195
D V EG V C A G P P I+W RH+ S+ L I G+
Sbjct: 441 DRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGT------LRISGVAL 494
Query: 196 DQAGEYECSAENDV-SFPDVRKVKVVVNFAPTIQEIKSG-TVTPGRSGLIRCEGAGVPPP 253
G+YEC A N + S V + V P I S TV G + + C G P P
Sbjct: 495 HDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEP 554
Query: 254 AFEWYK-GEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNAS--L 310
A W K G + +G+ I S LT+ +V G Y CVA N +G+ + S L
Sbjct: 555 AITWNKDGVQVTESGKFHI-----SPEGFLTINDVGPADAGRYECVARNTIGSASVSMVL 609
Query: 311 PLNPPSTAQYG 321
+N P ++ G
Sbjct: 610 SVNVPDVSRNG 620
Score = 80.5 bits (197), Expect = 2e-15
Identities = 77/289 (26%), Positives = 116/289 (40%), Gaps = 42/289 (14%)
Query: 50 VRKGDTAVLRCYLEDGASKGA-WLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNV 108
V G+T C E WL ++ + D R+++ D +L IQN
Sbjct: 257 VTSGNTVYFTCRAEGNPKPEIIWLRNNNEL-----SMKTDSRLNLLD----DGTLMIQNT 307
Query: 109 DVTDDGPYTCSVQ-TQHTPRTMQVHLTV---QVPPKIYDISNDMTVNEGTNVTLTCLATG 164
TD G Y C + +T +V L P + V G +VTL C ATG
Sbjct: 308 QETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECSATG 367
Query: 165 KPEPSISWRH-------ISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKV 217
P P ISW + P +G L I + + +GEY CSA N++ V
Sbjct: 368 HPPPRISWTRGDRTPLPVDPRVNITPSGG-LYIQNVVQGDSGEYACSATNNID--SVHAT 424
Query: 218 KVVVNFAPTIQEIKSGTVTP-------GRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQG 270
++ +Q + TVTP G++ +CE G PPP W KG +L ++
Sbjct: 425 AFII-----VQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRH 479
Query: 271 IIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTN--ASLPLNPPST 317
+++ + L ++ V G Y C A N +G+ A L + P T
Sbjct: 480 LVLSS----GTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVT 524
Score = 63.2 bits (152), Expect = 3e-10
Identities = 51/198 (25%), Positives = 80/198 (40%), Gaps = 18/198 (9%)
Query: 139 PKIYDISNDMTVNEGTNVTLTCLATGKPEPSISW--RHISPSAKPFENGQYLD-----IY 191
P+I D V G V TC A G P+P I W + S K LD I
Sbjct: 246 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQ 305
Query: 192 GITRDQAGEYECSAENDVSFPDVRKVKVVVNF-----APT-IQEIKSGTVTPGRSGLIRC 245
G Y+C A+N +V+ +V + + PT + + ++ V G S + C
Sbjct: 306 NTQETDQGIYQCMAKNVAG--EVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLEC 363
Query: 246 EGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGT 305
G PPP W +G++ + N + L + NV Q G Y C A N + +
Sbjct: 364 SATGHPPPRISWTRGDRTPLPVDPRV---NITPSGGLYIQNVVQGDSGEYACSATNNIDS 420
Query: 306 TNASLPLNPPSTAQYGIT 323
+A+ + + Q+ +T
Sbjct: 421 VHATAFIIVQALPQFTVT 438
>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
Length = 398
Score = 86.7 bits (213), Expect = 3e-17
Identities = 82/350 (23%), Positives = 136/350 (38%), Gaps = 37/350 (10%)
Query: 17 LAAVLLSLCCLLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGA-WLNRS 75
L +LL CC P Q PW + + ++ G T VL+C ++D W N +
Sbjct: 9 LLLLLLFACCWAPGGANLSQDDSQPWTSDETVVA--GGTVVLKCQVKDHEDSSLQWSNPA 66
Query: 76 SIIFAGGDKWSV-DPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLT 134
G+K ++ D R+ + T + S+ I NV + D+G YTCS+ T +
Sbjct: 67 QQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTV 126
Query: 135 VQVPPKIYDISNDMTVNEGTNVTLTCLATG-KPEPSISWR-------------HISPSAK 180
+ +P K ++ E TL C ++G KP ++WR P+ K
Sbjct: 127 LGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGK 186
Query: 181 PFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKV--KVVVNFAPTIQEIKSGTVTP- 237
F + D CS ++ R ++ V + PT I+ P
Sbjct: 187 TFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAM-IRPDPPHPR 245
Query: 238 -GRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYT 296
G+ L+ CEG G P P ++ L+ + + + S L + + G Y
Sbjct: 246 EGQKLLLHCEGRGNPVP-------QQYLWEKEGSVPPLKMTQESALIFPFLNKSDSGTYG 298
Query: 297 CVAANKLGTTNASLPLN-------PPSTAQYGITGSADVLFSCWYLVLTL 339
C A + +G+ A LN P S++ Y V F + L++ L
Sbjct: 299 CTATSNMGSYKAYYTLNVNDPSPVPSSSSTYHAIIGGIVAFIVFLLLIML 348
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 85.9 bits (211), Expect = 5e-17
Identities = 70/226 (30%), Positives = 96/226 (42%), Gaps = 15/226 (6%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLA 162
LQI+ VD+ D+G YTC+ +V L V VPP I + V E +VTL CLA
Sbjct: 659 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLA 718
Query: 163 TGKPEPSISW----RHISP--SAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRK 216
+G P P +SW + +S +G+ L I AG Y C A N ++R
Sbjct: 719 SGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELR- 777
Query: 217 VKVVVNFAP--TIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYK-GEKKLFNGQQGIII 273
+ VN P T+ G V + C G P P W K G G G +
Sbjct: 778 YGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPG--L 835
Query: 274 QNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPS 316
Q F +LT+ + G Y+CVA + +G + L PPS
Sbjct: 836 QVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPS 881
Score = 82.8 bits (203), Expect = 4e-16
Identities = 93/323 (28%), Positives = 134/323 (41%), Gaps = 32/323 (9%)
Query: 21 LLSLCCLLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRSSIIFA 80
L+ L L+P PA + P D ++VR GD AVL C + A + +
Sbjct: 1829 LVQLSVLVP---PAFRQA--PRGPQDAVLVRVGDKAVLSCETD------ALPEPTVTWYK 1877
Query: 81 GGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPK 140
G + R +R L+IQ V+D G Y+C V LTVQVPP
Sbjct: 1878 DGQPLVLAQRTQALRGGQR---LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPP- 1933
Query: 141 IYDISNDMTVNE--GTNVTLTCLATGKPEPSISW----RHISPSA--KPFENGQYLDIYG 192
++ TV++ G+ + LTC +G P P+++W + SA G L +
Sbjct: 1934 TFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSR 1993
Query: 193 ITRDQAGEYECSAENDVSFPDVRKVKVV-VNFAPTIQE---IKSGTVTPGRSGLIRCEGA 248
+ QAG Y C AEN + + RK VV V AP I+ + V G+ + CE
Sbjct: 1994 LQPAQAGTYTCVAENTQA--EARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEAD 2051
Query: 249 GVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNA 308
G PPP W K L G ++ + L + + G YTCVA N G
Sbjct: 2052 GQPPPDVAWLKDGSPL-GQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDAR 2110
Query: 309 SLPLN--PPSTAQYGITGSADVL 329
+N P T + G GS ++
Sbjct: 2111 LHTVNVLVPPTIKQGADGSGTLV 2133
Score = 82.0 bits (201), Expect = 7e-16
Identities = 60/208 (28%), Positives = 85/208 (40%), Gaps = 26/208 (12%)
Query: 112 DDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSIS 171
D + C V + +TV VPP I D D TV V LTC +TG P P++S
Sbjct: 2639 DSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVS 2698
Query: 172 WR-------------HISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVK 218
W +SPS E GQ L I+ AG Y CSA N + V
Sbjct: 2699 WSKAGAQLGARGSGYRVSPSG-ALEIGQALPIH------AGRYTCSARNSAGVAH-KHVF 2750
Query: 219 VVVNFAPTIQEIKSGT-VTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFS 277
+ V +P ++ + S L+ CE +G+P P W K + G ++
Sbjct: 2751 LTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQ 2810
Query: 278 TRSILTVTNVTQEHFGNYTCVAANKLGT 305
R + + + E GNY C+A N G+
Sbjct: 2811 LR----IAHASPEDAGNYLCIAKNSAGS 2834
Score = 80.5 bits (197), Expect = 2e-15
Identities = 61/230 (26%), Positives = 100/230 (43%), Gaps = 20/230 (8%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY---DISNDMTVNEGTNVTLT 159
L + + +G YTC + + L V VPP+I + ++V + TL
Sbjct: 1029 LYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLE 1088
Query: 160 CLATGKPEPSISW-RHISPSAKPF-----ENGQYLDIYGITRDQAGEYECSAENDVSFPD 213
C ATGKP P+++W R P GQ L + G Y C AEN +
Sbjct: 1089 CNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAE 1148
Query: 214 VRKVKVVVNFAPTI----QEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQ 269
RK ++ V P + + + T + CE G+PPPA W++GE+ + G+
Sbjct: 1149 -RKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGED 1207
Query: 270 GIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLP---LNPPS 316
++ + +L +T ++ G Y+C+A+N+ G + L PPS
Sbjct: 1208 TYLL---AGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPS 1254
Score = 79.7 bits (195), Expect = 4e-15
Identities = 63/220 (28%), Positives = 94/220 (42%), Gaps = 27/220 (12%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLA 162
L+I + D G Y C + + L VQVPP I + D++ EG++ L C A
Sbjct: 2811 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKA 2870
Query: 163 TGKPEPSISW----RHISPSAKPF---ENGQYLDIYGITRDQAGEYECSAENDVSFPDVR 215
G PEP+I+W + +S + F +G+ L + + AG Y C+AEN V R
Sbjct: 2871 RGSPEPNITWDKDGQPVSGAEGKFTIQPSGELL-VKNLEGQDAGTYTCTAENAVGRAR-R 2928
Query: 216 KVKVVVNFAPTIQEIKSGTVTPGRSGL-------IRCEGAGVPPPAFEWYKGEKKLFNGQ 268
+V + + P T PG L +RC G P P W ++ + G
Sbjct: 2929 RVHLTILVLPVF------TTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG- 2981
Query: 269 QGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNA 308
+ S L V++E G Y C A N++G T A
Sbjct: 2982 ----VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQA 3017
Score = 78.6 bits (192), Expect = 8e-15
Identities = 75/270 (27%), Positives = 116/270 (42%), Gaps = 31/270 (11%)
Query: 50 VRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVD 109
+R GD LRC A++G+ R W+V+ R ++++D +Q
Sbjct: 2949 LRLGDRLWLRC-----AARGSPTPRIG--------WTVNDRPVTEGVSEQDGGSTLQRAA 2995
Query: 110 VT--DDGPYTCSVQTQ--HTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGK 165
V+ D G Y C + + T VH+ + P + + + G ++ L C+ G
Sbjct: 2996 VSREDSGTYVCWAENRVGRTQAVSFVHVK-EAPVLQGEAFSYLVEPVGGSIQLDCVVRGD 3054
Query: 166 PEPSISW------RHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKV 219
P P I W S +NG L I+ RD AG Y+C AEN++ + V +
Sbjct: 3055 PVPDIHWIKDGLPLRGSHLRHQLQNGS-LTIHRTERDDAGRYQCLAENEMGVAK-KVVIL 3112
Query: 220 VVNFAPTIQ-EIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFST 278
V+ AP Q E + TV G +RC+ G P P EW + + L ++ + + S
Sbjct: 3113 VLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGS- 3171
Query: 279 RSILTVTNVTQEHFGNYTCVAANKLGTTNA 308
L + NV G Y CVA N LG+ A
Sbjct: 3172 ---LWLENVETGDAGTYDCVAHNLLGSATA 3198
Score = 75.9 bits (185), Expect = 5e-14
Identities = 62/238 (26%), Positives = 101/238 (42%), Gaps = 38/238 (15%)
Query: 101 YSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY--DISNDMTVNE-----G 153
+ LQI N D G YTC V + H+ V +PP I D ++ V E
Sbjct: 1404 HGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVN 1463
Query: 154 TNVTLTCLATGKPEPSISW----RHISPSAK--PFENGQYLDIYGITRDQAGEYECSAEN 207
+ +TL C + P P+I W + ++PS++ G+ L I +G Y C A N
Sbjct: 1464 STLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATN 1523
Query: 208 DVSFPDVRKVKVVVNFAPTIQEI---------------KSGTVTPGRS------GLIRCE 246
V+ D + V++ P Q++ G VT R + C+
Sbjct: 1524 -VAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCD 1582
Query: 247 GAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 304
+PPP WY+ ++ L G + ++Q +L + V E+ G Y+C A+N++G
Sbjct: 1583 TNAIPPPDLTWYREDQPLSAGDEVSVLQG---GRVLQIPLVRAENAGRYSCKASNEVG 1637
Score = 73.9 bits (180), Expect = 2e-13
Identities = 63/232 (27%), Positives = 94/232 (40%), Gaps = 19/232 (8%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY----DISNDMTVNEGTNVTL 158
LQI V + G Y+C + + L V PP I ++ ++TVN + V+L
Sbjct: 1615 LQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSL 1674
Query: 159 TCLATGKPEPSISWRH------ISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFP 212
C A G P P+ISW SP + E+GQ L + A Y C AEN
Sbjct: 1675 QCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA 1734
Query: 213 DVRKVKVVVNFAPTIQ--EIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQG 270
+ + + V P I +++ T S + C+ P P WYK + L G++
Sbjct: 1735 E-KLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEV 1793
Query: 271 IIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPSTAQ 319
++ T L + G YTC A N G + L+ PP+ Q
Sbjct: 1794 FLLPGTHT---LQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQ 1842
Score = 72.8 bits (177), Expect = 4e-13
Identities = 61/222 (27%), Positives = 96/222 (43%), Gaps = 20/222 (9%)
Query: 96 LNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKI--YDISNDMTVNEG 153
L+ ++L+I V + D G +TC + L VQVPP + + ND+ V G
Sbjct: 2171 LHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRG 2230
Query: 154 TNVTLTCLATGKPEPSISWRHISPS--AKPFENGQYLDIYGITRDQAGEYECSAENDVSF 211
+ V L C A G P P +SW ++ E G L + + +G Y C A ++
Sbjct: 2231 SLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAG- 2289
Query: 212 PDVRKVKVVVNFAPTIQEIKSGT---VTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQ 268
R ++ V P I++ T +TPG + C+ G P P W+K +GQ
Sbjct: 2290 EARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHK------DGQ 2343
Query: 269 QGIIIQNFSTRS-ILTVTNVTQEHFGNYTCVAANKLGTTNAS 309
++N S + +L V + G YTC+A + G S
Sbjct: 2344 ALTRLENNSRATRVLRVRDA-----GLYTCLAESPAGAIEKS 2380
Score = 72.4 bits (176), Expect = 6e-13
Identities = 56/214 (26%), Positives = 88/214 (41%), Gaps = 18/214 (8%)
Query: 101 YSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDI----SNDMTVNEGTNV 156
++LQ+ ++D G YTC V L+V VPP + + V G
Sbjct: 1800 HTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKA 1859
Query: 157 TLTCLATGKPEPSISWRH------ISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVS 210
L+C PEP+++W ++ + GQ L+I G Y C N V+
Sbjct: 1860 VLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSN-VA 1918
Query: 211 FPDVRKVKVVVNFAPTIQEIKSGTVT--PGRSGLIRCEGAGVPPPAFEWYKGEKKL-FNG 267
VR + V PT + K+ TV+ G ++ C+ +GVP P W K + +
Sbjct: 1919 GEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSA 1978
Query: 268 QQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAAN 301
G++ S L ++ + G YTCVA N
Sbjct: 1979 VHGVV----SRGGRLQLSRLQPAQAGTYTCVAEN 2008
Score = 72.0 bits (175), Expect = 8e-13
Identities = 66/251 (26%), Positives = 103/251 (41%), Gaps = 20/251 (7%)
Query: 98 KRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVT 157
+R LQ+Q + D G Y+C+ + ++ + + P I + V+
Sbjct: 2441 ERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTAL 2500
Query: 158 LTCLATGKPEPSISWRH----ISPSAKPFE---NGQYLDIYGITRDQAGEYECSAENDVS 210
L C A G P P +SWR + P + FE G L I + AG Y C A N
Sbjct: 2501 LPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGS-LRIQPVLAQDAGHYLCLASNSAG 2559
Query: 211 FPDVRKVKVVVNFAPTIQEIKSG-TVTPGRSGLIRCEGAGVPPPAFEWYK-GEKKLFNGQ 268
D + + V P I S T+T L+ CE +G P P W+K G+K F Q
Sbjct: 2560 -SDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQ 2618
Query: 269 QGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPSTA----QYG 321
QG + L +T + + CV +N++G + + PP+ A +
Sbjct: 2619 QG--AYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFT 2676
Query: 322 ITGSADVLFSC 332
+T A V+ +C
Sbjct: 2677 VTMMAPVVLTC 2687
Score = 70.9 bits (172), Expect = 2e-12
Identities = 61/224 (27%), Positives = 85/224 (37%), Gaps = 30/224 (13%)
Query: 101 YSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY--DISNDMTVNEGTNVTL 158
+ L++ D G Y+C + + V VPP I D+ + V +G L
Sbjct: 1215 WMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHL 1274
Query: 159 TCLATGKPEPSISW------------RHISPSAKPFENGQYLDIYGITRDQAGEYECSAE 206
C TG P+P ++W HISP +G L + AG Y C A
Sbjct: 1275 MCNVTGHPQPKLTWFKDGRPLARGDAHHISP------DGVLLQVLQANLSSAGHYSCIAA 1328
Query: 207 NDVSFPDVRKVKVVVNFAPTI------QEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKG 260
N V + ++ V APTI + TVT + CE P P W K
Sbjct: 1329 NAVG-EKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMK- 1386
Query: 261 EKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 304
+ F + IQ L + N +E G YTCV N+LG
Sbjct: 1387 DGAPFEASRN--IQLLPGTHGLQILNAQKEDAGQYTCVVTNELG 1428
Score = 68.9 bits (167), Expect = 6e-12
Identities = 66/256 (25%), Positives = 96/256 (37%), Gaps = 38/256 (14%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCL 161
SL+IQ V D G Y C L V PP I +++T+ T L C
Sbjct: 2536 SLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCE 2595
Query: 162 ATGKPEPSISWRHISPSAKPFENGQYLDI------YGITRDQA-----------GEYECS 204
A+G P+P + W +++GQ LD Y + A ++EC
Sbjct: 2596 ASGSPKPLVVW---------WKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECV 2646
Query: 205 AENDVSFPDVRKVKVVVNFAPTIQEIKSG-TVTPGRSGLIRCEGAGVPPPAFEWYKGEKK 263
N+V R +V V+ PTI + ++ TVT ++ C G+P P W K +
Sbjct: 2647 VSNEVGEAH-RLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQ 2705
Query: 264 LFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGT-------TNASLPLNPPS 316
L G + S L + H G YTC A N G T + P+ P
Sbjct: 2706 LGARGSGYRV---SPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPL 2762
Query: 317 TAQYGITGSADVLFSC 332
+ +VL C
Sbjct: 2763 PSVVRAVAEEEVLLPC 2778
Score = 68.6 bits (166), Expect = 8e-12
Identities = 60/237 (25%), Positives = 98/237 (41%), Gaps = 24/237 (10%)
Query: 85 WSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDI 144
W D +S ++ SLQ++ V D G Y+C ++ LTV PP I D
Sbjct: 2249 WMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDS 2308
Query: 145 S--NDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYE 202
++++ G + L C A G P+P+I+W + EN RD AG Y
Sbjct: 2309 GQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRD-AGLYT 2367
Query: 203 CSAENDVSFPDVRKVKVVVNFAPTIQEIKSGT----VTPGRSGLIRCEGAGVPPPAFEWY 258
C AE+ + + +V V P I + + PG+ ++ C P P W+
Sbjct: 2368 CLAESPAGAIE-KSFRVRVQAPPNIVGPRGPRFVVGLAPGQL-VLECSVEAEPAPKITWH 2425
Query: 259 KGEKKLFNGQQGIIIQ-----NFSTRS-ILTVTNVTQEHFGNYTCVAANKLGTTNAS 309
+ GI++Q F R L + ++ G+Y+C A N G+T+ +
Sbjct: 2426 R---------DGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVA 2473
Score = 67.8 bits (164), Expect = 1e-11
Identities = 57/223 (25%), Positives = 91/223 (40%), Gaps = 16/223 (7%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNE---GTNVTLT 159
LQ+ +D G YTC L V VPP I V + G V L
Sbjct: 367 LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALE 426
Query: 160 CLATGKPEPSISWRHIS-PSAKPFE-----NGQYLDIYGITRDQAGEYECSAENDVSFPD 213
C+A G P P++SW H P A+ E +G L + +G Y C A +
Sbjct: 427 CVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAG-EA 485
Query: 214 VRKVKVVVNFAPTI---QEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQG 270
V + V V P + + + T G+ + C+ +G P P +W + + ++
Sbjct: 486 VLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRP---AEEL 542
Query: 271 IIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 313
+Q S + L + +V +H G + C A N+ GT A + ++
Sbjct: 543 AGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVS 585
Score = 67.4 bits (163), Expect = 2e-11
Identities = 65/249 (26%), Positives = 98/249 (39%), Gaps = 24/249 (9%)
Query: 96 LNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKI---YDISNDMTVNE 152
L + SL ++ G Y+C + + L+V VPP++ D ++T
Sbjct: 1116 LQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAAL 1175
Query: 153 GTNVTLTCLATGKPEPSISWRHISPSAKPFEN------GQYLDIYGITRDQAGEYECSAE 206
+ +TL C A G P P+I W P E+ G L + +G Y C A
Sbjct: 1176 HSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLAS 1235
Query: 207 NDVSFPDVRKVKVVVNFAPTIQE------IKSGTVTPGRSGLIRCEGAGVPPPAFEWYKG 260
N+ R V V P+I+ IK V G++ + C G P P W+K
Sbjct: 1236 NEAG-EARRNFSVEVLVPPSIENEDLEEVIK---VLDGQTAHLMCNVTGHPQPKLTWFKD 1291
Query: 261 EKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG--TTNASLPLNPPSTA 318
+ L G I + +L V G+Y+C+AAN +G T + L + T
Sbjct: 1292 GRPLARGDAHHISPD---GVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTI 1348
Query: 319 QYGITGSAD 327
G SAD
Sbjct: 1349 LGGAEDSAD 1357
Score = 59.7 bits (143), Expect = 4e-09
Identities = 61/233 (26%), Positives = 92/233 (39%), Gaps = 25/233 (10%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLA 162
L + + +D G Y+C + V L V +PP I +++V +V L C +
Sbjct: 844 LTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQS 903
Query: 163 TGKPEPSISW----RHISP-------SAKPFENGQYLDIYGITRDQAGEYECSAENDVSF 211
P P +SW R + P + K D++ AG Y C A N
Sbjct: 904 HAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVW-----DAGHYTCEALNQAGR 958
Query: 212 PDVRKVKVVVNFAPT--IQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQ 269
+ + + V AP ++E + TV G + CE GVP P W K + L +
Sbjct: 959 SE-KHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPL--PGE 1015
Query: 270 GIIIQNFSTRSILTVTNVTQ-EHFGNYTCVAANKLGTTNASLPLN---PPSTA 318
G +Q+ S L Q G YTC +N +G ++ L L PP A
Sbjct: 1016 GAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIA 1068
Score = 58.9 bits (141), Expect = 7e-09
Identities = 62/238 (26%), Positives = 87/238 (36%), Gaps = 29/238 (12%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHL---TVQVPPKIY---DISNDMTVNEGTN 155
SL ++ + +D G YTC H P L V VPP I D S + G
Sbjct: 2083 SLVLKGLRASDAGAYTC---VAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGEL 2139
Query: 156 VTLTCLATGKPEPSISWRH------ISPSAKPFENGQYLDIYGITRDQAGEYECSAENDV 209
VT+ C G P +SW +S +G L I + AG + C A +
Sbjct: 2140 VTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPA 2199
Query: 210 SFPDVRKVKVVVNFAPTIQEIK-SGTVTPGRSGLIR--CEGAGVPPPAFEWYKGEKKLFN 266
D R + V P ++ ++ V R L+ CE GVP P W K + L +
Sbjct: 2200 GVAD-RNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLS 2258
Query: 267 GQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL---NPPSTAQYG 321
Q+ L + V G Y+CVA ++ G L PP G
Sbjct: 2259 -------QSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSG 2309
Score = 57.8 bits (138), Expect = 1e-08
Identities = 52/214 (24%), Positives = 83/214 (38%), Gaps = 16/214 (7%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY--DISNDMTVNEGTNVTLTC 160
L+I V D+G Y C + + L V PP I+ + + ++ V E V L C
Sbjct: 274 LRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLC 333
Query: 161 LATGKPEPSISW------RHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDV 214
A G P P+I+W S G+ L + AG Y C A N V +
Sbjct: 334 EARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAE- 392
Query: 215 RKVKVVVNFAPTIQEIKSG----TVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQG 270
+ ++ V PTI+ GR + C G P P W+ + +
Sbjct: 393 KATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNES 452
Query: 271 IIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 304
+ + S+L + + + G Y+CVA++ G
Sbjct: 453 RL---ETDGSVLRLESPGEASSGLYSCVASSPAG 483
Score = 52.8 bits (125), Expect = 5e-07
Identities = 47/177 (26%), Positives = 71/177 (40%), Gaps = 17/177 (9%)
Query: 153 GTNVTLTCLATGKPEPSISWRHI-------SPSAKPFENGQYLDIYGITRDQAGEYECSA 205
G +V L C +G P P + W P + E+GQ L I G G Y+C A
Sbjct: 232 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVA 291
Query: 206 ENDVSFPDVRKVKVVVNFAPTI-QEIKSGTVTPGRSGLIR--CEGAGVPPPAFEWYKGEK 262
+ R ++ V+ PTI ++G V L++ CE GVP P W+K
Sbjct: 292 FSPAG-QQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGA 350
Query: 263 KLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPS 316
L + + + L + G YTC A+N +G + L+ PP+
Sbjct: 351 LLPTSTKVVYTRGGRQ---LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPT 404
Score = 52.8 bits (125), Expect = 5e-07
Identities = 38/125 (30%), Positives = 51/125 (40%), Gaps = 7/125 (5%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCL 161
SL I + D G Y C + + V L +Q P DMTV G +V L C
Sbjct: 3081 SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQ 3140
Query: 162 ATGKPEPSISW------RHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVR 215
ATG+P P+I W S + +G L + + AG Y+C A N + R
Sbjct: 3141 ATGEPTPTIEWLQAGQPLRASRRLRTLPDGS-LWLENVETGDAGTYDCVAHNLLGSATAR 3199
Query: 216 KVKVV 220
VV
Sbjct: 3200 AFLVV 3204
Score = 51.6 bits (122), Expect = 1e-06
Identities = 33/111 (29%), Positives = 49/111 (44%), Gaps = 13/111 (11%)
Query: 160 CLATGKPEPSISWR--------HISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSF 211
C G P+P ++WR H P E G L + ++ +G+YEC A N+V
Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGS-LFLASVSPADSGDYECQATNEVGS 82
Query: 212 PDVRKVKVVVNFAPTIQEIKSGTVTPGRSG---LIRCEGAGVPPPAFEWYK 259
R+ K+VV P+I+E G +G + C+ G P P W K
Sbjct: 83 TS-RRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLK 132
Score = 44.3 bits (103), Expect = 2e-04
Identities = 60/272 (22%), Positives = 91/272 (33%), Gaps = 49/272 (18%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVN--EGTNVTLT 159
SL + +V D G Y C + + + L V VPP I + V+ G ++TL
Sbjct: 58 SLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLE 117
Query: 160 CLATGKPEPSI----------------------SWRHISPSAKPFENGQYLDIYGITRDQ 197
C A G P P I W + + + GQ L I +
Sbjct: 118 CDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVG-GHRLLDEGQSLHFPRIQPGR 176
Query: 198 AGEYECSAENDVS--------------FPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGL- 242
+G A FP P++ + G +G
Sbjct: 177 SGRRGAQAGGSAQTKAPWXAGLAGFEQFPTPHAFSPPA--PPSVLGAGAAQEVLGLAGAD 234
Query: 243 --IRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAA 300
++C +GVP P EW K + + G + +Q +T ++V E G Y CVA
Sbjct: 235 VELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDE--GRYQCVAF 292
Query: 301 NKLGTTNASLPLN---PPSTAQYGITGSADVL 329
+ G L PP+ TG V+
Sbjct: 293 SPAGQQARDFQLRVHAPPTIWGSNETGEVAVM 324
Score = 36.2 bits (82), Expect = 0.046
Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 7/81 (8%)
Query: 245 CEGAGVPPPAFEWYKG-EKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKL 303
C G P P W KG + +GQ G+ + + L + +V+ G+Y C A N++
Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGS---LFLASVSPADSGDYECQATNEV 80
Query: 304 GTTNASLPL---NPPSTAQYG 321
G+T+ L PPS + G
Sbjct: 81 GSTSRRAKLVVYVPPSIREDG 101
Score = 28.9 bits (63), Expect = 7.3
Identities = 25/95 (26%), Positives = 34/95 (35%), Gaps = 12/95 (12%)
Query: 47 NMMVRKGDTAVLRCYLEDGASKGA-WLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQI 105
+M VR GD LRC + WL + R S D SL +
Sbjct: 3126 DMTVRSGDDVALRCQATGEPTPTIEWLQAGQPL-----------RASRRLRTLPDGSLWL 3174
Query: 106 QNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPK 140
+NV+ D G Y C T + L V+ P+
Sbjct: 3175 ENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 3209
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 85.9 bits (211), Expect = 5e-17
Identities = 70/226 (30%), Positives = 96/226 (42%), Gaps = 15/226 (6%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLA 162
LQI+ VD+ D+G YTC+ +V L V VPP I + V E +VTL CLA
Sbjct: 568 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLA 627
Query: 163 TGKPEPSISW----RHISP--SAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRK 216
+G P P +SW + +S +G+ L I AG Y C A N ++R
Sbjct: 628 SGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELR- 686
Query: 217 VKVVVNFAP--TIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYK-GEKKLFNGQQGIII 273
+ VN P T+ G V + C G P P W K G G G +
Sbjct: 687 YGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPG--L 744
Query: 274 QNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPS 316
Q F +LT+ + G Y+CVA + +G + L PPS
Sbjct: 745 QVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPS 790
Score = 82.8 bits (203), Expect = 4e-16
Identities = 93/323 (28%), Positives = 134/323 (41%), Gaps = 32/323 (9%)
Query: 21 LLSLCCLLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRSSIIFA 80
L+ L L+P PA + P D ++VR GD AVL C + A + +
Sbjct: 1738 LVQLSVLVP---PAFRQA--PRGPQDAVLVRVGDKAVLSCETD------ALPEPTVTWYK 1786
Query: 81 GGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPK 140
G + R +R L+IQ V+D G Y+C V LTVQVPP
Sbjct: 1787 DGQPLVLAQRTQALRGGQR---LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPP- 1842
Query: 141 IYDISNDMTVNE--GTNVTLTCLATGKPEPSISW----RHISPSA--KPFENGQYLDIYG 192
++ TV++ G+ + LTC +G P P+++W + SA G L +
Sbjct: 1843 TFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSR 1902
Query: 193 ITRDQAGEYECSAENDVSFPDVRKVKVV-VNFAPTIQE---IKSGTVTPGRSGLIRCEGA 248
+ QAG Y C AEN + + RK VV V AP I+ + V G+ + CE
Sbjct: 1903 LQPAQAGTYTCVAENTQA--EARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEAD 1960
Query: 249 GVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNA 308
G PPP W K L G ++ + L + + G YTCVA N G
Sbjct: 1961 GQPPPDVAWLKDGSPL-GQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDAR 2019
Query: 309 SLPLN--PPSTAQYGITGSADVL 329
+N P T + G GS ++
Sbjct: 2020 LHTVNVLVPPTIKQGADGSGTLV 2042
Score = 82.0 bits (201), Expect = 7e-16
Identities = 60/208 (28%), Positives = 85/208 (40%), Gaps = 26/208 (12%)
Query: 112 DDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSIS 171
D + C V + +TV VPP I D D TV V LTC +TG P P++S
Sbjct: 2548 DSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVS 2607
Query: 172 WR-------------HISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVK 218
W +SPS E GQ L I+ AG Y CSA N + V
Sbjct: 2608 WSKAGAQLGARGSGYRVSPSG-ALEIGQALPIH------AGRYTCSARNSAGVAH-KHVF 2659
Query: 219 VVVNFAPTIQEIKSGT-VTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFS 277
+ V +P ++ + S L+ CE +G+P P W K + G ++
Sbjct: 2660 LTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQ 2719
Query: 278 TRSILTVTNVTQEHFGNYTCVAANKLGT 305
R + + + E GNY C+A N G+
Sbjct: 2720 LR----IAHASPEDAGNYLCIAKNSAGS 2743
Score = 80.5 bits (197), Expect = 2e-15
Identities = 61/230 (26%), Positives = 100/230 (43%), Gaps = 20/230 (8%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY---DISNDMTVNEGTNVTLT 159
L + + +G YTC + + L V VPP+I + ++V + TL
Sbjct: 938 LYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLE 997
Query: 160 CLATGKPEPSISW-RHISPSAKPF-----ENGQYLDIYGITRDQAGEYECSAENDVSFPD 213
C ATGKP P+++W R P GQ L + G Y C AEN +
Sbjct: 998 CNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAE 1057
Query: 214 VRKVKVVVNFAPTI----QEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQ 269
RK ++ V P + + + T + CE G+PPPA W++GE+ + G+
Sbjct: 1058 -RKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGED 1116
Query: 270 GIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLP---LNPPS 316
++ + +L +T ++ G Y+C+A+N+ G + L PPS
Sbjct: 1117 TYLL---AGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPS 1163
Score = 79.7 bits (195), Expect = 4e-15
Identities = 63/220 (28%), Positives = 94/220 (42%), Gaps = 27/220 (12%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLA 162
L+I + D G Y C + + L VQVPP I + D++ EG++ L C A
Sbjct: 2720 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKA 2779
Query: 163 TGKPEPSISW----RHISPSAKPF---ENGQYLDIYGITRDQAGEYECSAENDVSFPDVR 215
G PEP+I+W + +S + F +G+ L + + AG Y C+AEN V R
Sbjct: 2780 RGSPEPNITWDKDGQPVSGAEGKFTIQPSGELL-VKNLEGQDAGTYTCTAENAVGRAR-R 2837
Query: 216 KVKVVVNFAPTIQEIKSGTVTPGRSGL-------IRCEGAGVPPPAFEWYKGEKKLFNGQ 268
+V + + P T PG L +RC G P P W ++ + G
Sbjct: 2838 RVHLTILVLPVF------TTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG- 2890
Query: 269 QGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNA 308
+ S L V++E G Y C A N++G T A
Sbjct: 2891 ----VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQA 2926
Score = 77.0 bits (188), Expect = 2e-14
Identities = 75/270 (27%), Positives = 115/270 (42%), Gaps = 31/270 (11%)
Query: 50 VRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVD 109
+R GD LRC A++G+ R W+V+ R ++++D +Q
Sbjct: 2858 LRLGDRLWLRC-----AARGSPTPRIG--------WTVNDRPVTEGVSEQDGGSTLQRAA 2904
Query: 110 VT--DDGPYTCSVQTQ--HTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGK 165
V+ D G Y C + + T VH+ + P + + + G ++ L C+ G
Sbjct: 2905 VSREDSGTYVCWAENRVGRTQAVSFVHVK-EAPVLQGEAFSYLVEPVGGSIQLDCVVRGD 2963
Query: 166 PEPSISW------RHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKV 219
P P I W S +NG L I RD AG Y+C AEN++ + V +
Sbjct: 2964 PVPDIHWIKDGLPLRGSHLRHQLQNGS-LTIRRTERDDAGRYQCLAENEMGVAK-KVVIL 3021
Query: 220 VVNFAPTIQ-EIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFST 278
V+ AP Q E + TV G +RC+ G P P EW + + L ++ + + S
Sbjct: 3022 VLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGS- 3080
Query: 279 RSILTVTNVTQEHFGNYTCVAANKLGTTNA 308
L + NV G Y CVA N LG+ A
Sbjct: 3081 ---LWLENVETGDAGTYDCVAHNLLGSATA 3107
Score = 75.1 bits (183), Expect = 9e-14
Identities = 62/238 (26%), Positives = 101/238 (42%), Gaps = 38/238 (15%)
Query: 101 YSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY--DISNDMTVNE-----G 153
+ LQI N D G YTC V + H+ V +PP I D ++ V E
Sbjct: 1313 HGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKTKVN 1372
Query: 154 TNVTLTCLATGKPEPSISW----RHISPSAK--PFENGQYLDIYGITRDQAGEYECSAEN 207
+ +TL C + P P+I W + ++PS++ G+ L I +G Y C A N
Sbjct: 1373 STLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATN 1432
Query: 208 DVSFPDVRKVKVVVNFAPTIQEI---------------KSGTVTPGRS------GLIRCE 246
V+ D + V++ P Q++ G VT R + C+
Sbjct: 1433 -VAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCD 1491
Query: 247 GAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 304
+PPP WY+ ++ L G + ++Q +L + V E+ G Y+C A+N++G
Sbjct: 1492 TNAIPPPDLTWYREDQPLSAGDEVSVLQG---GRVLQIPLVRAENAGRYSCKASNEVG 1546
Score = 73.9 bits (180), Expect = 2e-13
Identities = 63/232 (27%), Positives = 94/232 (40%), Gaps = 19/232 (8%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY----DISNDMTVNEGTNVTL 158
LQI V + G Y+C + + L V PP I ++ ++TVN + V+L
Sbjct: 1524 LQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSL 1583
Query: 159 TCLATGKPEPSISWRH------ISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFP 212
C A G P P+ISW SP + E+GQ L + A Y C AEN
Sbjct: 1584 QCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA 1643
Query: 213 DVRKVKVVVNFAPTIQ--EIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQG 270
+ + + V P I +++ T S + C+ P P WYK + L G++
Sbjct: 1644 E-KLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEV 1702
Query: 271 IIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPSTAQ 319
++ T L + G YTC A N G + L+ PP+ Q
Sbjct: 1703 FLLPGTHT---LQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQ 1751
Score = 72.8 bits (177), Expect = 4e-13
Identities = 61/222 (27%), Positives = 96/222 (43%), Gaps = 20/222 (9%)
Query: 96 LNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKI--YDISNDMTVNEG 153
L+ ++L+I V + D G +TC + L VQVPP + + ND+ V G
Sbjct: 2080 LHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRG 2139
Query: 154 TNVTLTCLATGKPEPSISWRHISPS--AKPFENGQYLDIYGITRDQAGEYECSAENDVSF 211
+ V L C A G P P +SW ++ E G L + + +G Y C A ++
Sbjct: 2140 SLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAG- 2198
Query: 212 PDVRKVKVVVNFAPTIQEIKSGT---VTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQ 268
R ++ V P I++ T +TPG + C+ G P P W+K +GQ
Sbjct: 2199 EARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHK------DGQ 2252
Query: 269 QGIIIQNFSTRS-ILTVTNVTQEHFGNYTCVAANKLGTTNAS 309
++N S + +L V + G YTC+A + G S
Sbjct: 2253 ALTRLENNSRATRVLRVRDA-----GLYTCLAESPAGAIEKS 2289
Score = 72.4 bits (176), Expect = 6e-13
Identities = 56/214 (26%), Positives = 88/214 (41%), Gaps = 18/214 (8%)
Query: 101 YSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDI----SNDMTVNEGTNV 156
++LQ+ ++D G YTC V L+V VPP + + V G
Sbjct: 1709 HTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKA 1768
Query: 157 TLTCLATGKPEPSISWRH------ISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVS 210
L+C PEP+++W ++ + GQ L+I G Y C N V+
Sbjct: 1769 VLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSN-VA 1827
Query: 211 FPDVRKVKVVVNFAPTIQEIKSGTVT--PGRSGLIRCEGAGVPPPAFEWYKGEKKL-FNG 267
VR + V PT + K+ TV+ G ++ C+ +GVP P W K + +
Sbjct: 1828 GEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSA 1887
Query: 268 QQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAAN 301
G++ S L ++ + G YTCVA N
Sbjct: 1888 VHGVV----SRGGRLQLSRLQPAQAGTYTCVAEN 1917
Score = 72.0 bits (175), Expect = 8e-13
Identities = 66/251 (26%), Positives = 103/251 (41%), Gaps = 20/251 (7%)
Query: 98 KRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVT 157
+R LQ+Q + D G Y+C+ + ++ + + P I + V+
Sbjct: 2350 ERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTAL 2409
Query: 158 LTCLATGKPEPSISWRH----ISPSAKPFE---NGQYLDIYGITRDQAGEYECSAENDVS 210
L C A G P P +SWR + P + FE G L I + AG Y C A N
Sbjct: 2410 LPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGS-LRIQPVLAQDAGHYLCLASNSAG 2468
Query: 211 FPDVRKVKVVVNFAPTIQEIKSG-TVTPGRSGLIRCEGAGVPPPAFEWYK-GEKKLFNGQ 268
D + + V P I S T+T L+ CE +G P P W+K G+K F Q
Sbjct: 2469 -SDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQ 2527
Query: 269 QGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPSTA----QYG 321
QG + L +T + + CV +N++G + + PP+ A +
Sbjct: 2528 QG--AYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFT 2585
Query: 322 ITGSADVLFSC 332
+T A V+ +C
Sbjct: 2586 VTMMAPVVLTC 2596
Score = 70.9 bits (172), Expect = 2e-12
Identities = 61/224 (27%), Positives = 85/224 (37%), Gaps = 30/224 (13%)
Query: 101 YSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY--DISNDMTVNEGTNVTL 158
+ L++ D G Y+C + + V VPP I D+ + V +G L
Sbjct: 1124 WMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHL 1183
Query: 159 TCLATGKPEPSISW------------RHISPSAKPFENGQYLDIYGITRDQAGEYECSAE 206
C TG P+P ++W HISP +G L + AG Y C A
Sbjct: 1184 MCNVTGHPQPKLTWFKDGRPLARGDAHHISP------DGVLLQVLQANLSSAGHYSCIAA 1237
Query: 207 NDVSFPDVRKVKVVVNFAPTI------QEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKG 260
N V + ++ V APTI + TVT + CE P P W K
Sbjct: 1238 NAVG-EKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMK- 1295
Query: 261 EKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 304
+ F + IQ L + N +E G YTCV N+LG
Sbjct: 1296 DGAPFEASRN--IQLLPGTHGLQILNAQKEDAGQYTCVVTNELG 1337
Score = 68.9 bits (167), Expect = 6e-12
Identities = 66/256 (25%), Positives = 96/256 (37%), Gaps = 38/256 (14%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCL 161
SL+IQ V D G Y C L V PP I +++T+ T L C
Sbjct: 2445 SLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCE 2504
Query: 162 ATGKPEPSISWRHISPSAKPFENGQYLDI------YGITRDQA-----------GEYECS 204
A+G P+P + W +++GQ LD Y + A ++EC
Sbjct: 2505 ASGSPKPLVVW---------WKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECV 2555
Query: 205 AENDVSFPDVRKVKVVVNFAPTIQEIKSG-TVTPGRSGLIRCEGAGVPPPAFEWYKGEKK 263
N+V R +V V+ PTI + ++ TVT ++ C G+P P W K +
Sbjct: 2556 VSNEVGEAH-RLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQ 2614
Query: 264 LFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGT-------TNASLPLNPPS 316
L G + S L + H G YTC A N G T + P+ P
Sbjct: 2615 LGARGSGYRV---SPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPL 2671
Query: 317 TAQYGITGSADVLFSC 332
+ +VL C
Sbjct: 2672 PSVVRAVAEEEVLLPC 2687
Score = 68.6 bits (166), Expect = 8e-12
Identities = 60/237 (25%), Positives = 98/237 (41%), Gaps = 24/237 (10%)
Query: 85 WSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDI 144
W D +S ++ SLQ++ V D G Y+C ++ LTV PP I D
Sbjct: 2158 WMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDS 2217
Query: 145 S--NDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYE 202
++++ G + L C A G P+P+I+W + EN RD AG Y
Sbjct: 2218 GQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRD-AGLYT 2276
Query: 203 CSAENDVSFPDVRKVKVVVNFAPTIQEIKSGT----VTPGRSGLIRCEGAGVPPPAFEWY 258
C AE+ + + +V V P I + + PG+ ++ C P P W+
Sbjct: 2277 CLAESPAGAIE-KSFRVRVQAPPNIVGPRGPRFVVGLAPGQL-VLECSVEAEPAPKITWH 2334
Query: 259 KGEKKLFNGQQGIIIQ-----NFSTRS-ILTVTNVTQEHFGNYTCVAANKLGTTNAS 309
+ GI++Q F R L + ++ G+Y+C A N G+T+ +
Sbjct: 2335 R---------DGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVA 2382
Score = 67.8 bits (164), Expect = 1e-11
Identities = 59/230 (25%), Positives = 90/230 (39%), Gaps = 19/230 (8%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY--DISNDMTVNEGTNVTLT 159
SL + D G Y+C + Q HL V PP + + ++ G +V L
Sbjct: 88 SLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQ 147
Query: 160 CLATGKPEPSISWRHI-------SPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFP 212
C +G P P + W P + E+GQ L I G G Y+C A +
Sbjct: 148 CWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAG-Q 206
Query: 213 DVRKVKVVVNFAPTI-QEIKSGTVTPGRSGLIR--CEGAGVPPPAFEWYKGEKKLFNGQQ 269
R ++ V+ PTI ++G V L++ CE GVP P W+K L +
Sbjct: 207 QARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTK 266
Query: 270 GIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN---PPS 316
+ + L + G YTC A+N +G + L+ PP+
Sbjct: 267 VVYTRGGRQ---LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPT 313
Score = 67.8 bits (164), Expect = 1e-11
Identities = 57/223 (25%), Positives = 91/223 (40%), Gaps = 16/223 (7%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNE---GTNVTLT 159
LQ+ +D G YTC L V VPP I V + G V L
Sbjct: 276 LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALE 335
Query: 160 CLATGKPEPSISWRHIS-PSAKPFE-----NGQYLDIYGITRDQAGEYECSAENDVSFPD 213
C+A G P P++SW H P A+ E +G L + +G Y C A +
Sbjct: 336 CVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAG-EA 394
Query: 214 VRKVKVVVNFAPTI---QEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQG 270
V + V V P + + + T G+ + C+ +G P P +W + + ++
Sbjct: 395 VLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRP---AEEL 451
Query: 271 IIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 313
+Q S + L + +V +H G + C A N+ GT A + ++
Sbjct: 452 AGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVS 494
Score = 67.4 bits (163), Expect = 2e-11
Identities = 65/249 (26%), Positives = 98/249 (39%), Gaps = 24/249 (9%)
Query: 96 LNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKI---YDISNDMTVNE 152
L + SL ++ G Y+C + + L+V VPP++ D ++T
Sbjct: 1025 LQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAAL 1084
Query: 153 GTNVTLTCLATGKPEPSISWRHISPSAKPFEN------GQYLDIYGITRDQAGEYECSAE 206
+ +TL C A G P P+I W P E+ G L + +G Y C A
Sbjct: 1085 HSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLAS 1144
Query: 207 NDVSFPDVRKVKVVVNFAPTIQE------IKSGTVTPGRSGLIRCEGAGVPPPAFEWYKG 260
N+ R V V P+I+ IK V G++ + C G P P W+K
Sbjct: 1145 NEAG-EARRNFSVEVLVPPSIENEDLEEVIK---VLDGQTAHLMCNVTGHPQPKLTWFKD 1200
Query: 261 EKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG--TTNASLPLNPPSTA 318
+ L G I + +L V G+Y+C+AAN +G T + L + T
Sbjct: 1201 GRPLARGDAHHISPD---GVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTI 1257
Query: 319 QYGITGSAD 327
G SAD
Sbjct: 1258 LGGAEDSAD 1266
Score = 60.5 bits (145), Expect = 2e-09
Identities = 61/233 (26%), Positives = 92/233 (39%), Gaps = 25/233 (10%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLA 162
L + + +D G Y+C + V L V +PP I +++V +V L C +
Sbjct: 753 LTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQS 812
Query: 163 TGKPEPSISW----RHISP-------SAKPFENGQYLDIYGITRDQAGEYECSAENDVSF 211
P P +SW R + P + K D++ AG Y C A N
Sbjct: 813 HAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVW-----DAGHYTCEALNQAGH 867
Query: 212 PDVRKVKVVVNFAPT--IQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQ 269
+ + + V AP ++E + TV G + CE GVP P W K + L +
Sbjct: 868 SE-KHYNLNVWVAPVFPLRESHTLTVREGHPTRLSCECRGVPFPKISWRKDGQPL--PGE 924
Query: 270 GIIIQNFSTRSILTVTNVTQ-EHFGNYTCVAANKLGTTNASLPLN---PPSTA 318
G +Q+ S L Q G YTC +N +G ++ L L PP A
Sbjct: 925 GAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIA 977
Score = 58.9 bits (141), Expect = 7e-09
Identities = 62/238 (26%), Positives = 87/238 (36%), Gaps = 29/238 (12%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHL---TVQVPPKIY---DISNDMTVNEGTN 155
SL ++ + +D G YTC H P L V VPP I D S + G
Sbjct: 1992 SLVLKGLRASDAGAYTC---VAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGEL 2048
Query: 156 VTLTCLATGKPEPSISWRH------ISPSAKPFENGQYLDIYGITRDQAGEYECSAENDV 209
VT+ C G P +SW +S +G L I + AG + C A +
Sbjct: 2049 VTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPA 2108
Query: 210 SFPDVRKVKVVVNFAPTIQEIK-SGTVTPGRSGLIR--CEGAGVPPPAFEWYKGEKKLFN 266
D R + V P ++ ++ V R L+ CE GVP P W K + L +
Sbjct: 2109 GVAD-RNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLS 2167
Query: 267 GQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL---NPPSTAQYG 321
Q+ L + V G Y+CVA ++ G L PP G
Sbjct: 2168 -------QSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSG 2218
Score = 53.1 bits (126), Expect = 4e-07
Identities = 38/125 (30%), Positives = 52/125 (41%), Gaps = 7/125 (5%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCL 161
SL I+ + D G Y C + + V L +Q P DMTV G +V L C
Sbjct: 2990 SLTIRRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQ 3049
Query: 162 ATGKPEPSISW------RHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVR 215
ATG+P P+I W S + +G L + + AG Y+C A N + R
Sbjct: 3050 ATGEPTPTIEWLQAGQPLRASRRLRTLPDGS-LWLENVETGDAGTYDCVAHNLLGSATAR 3108
Query: 216 KVKVV 220
VV
Sbjct: 3109 AFLVV 3113
Score = 52.0 bits (123), Expect = 8e-07
Identities = 55/222 (24%), Positives = 82/222 (36%), Gaps = 32/222 (14%)
Query: 137 VPPKIYDISNDMTVN--EGTNVTLTCLATGKPEPSISWRHISPSA--------------- 179
VPP I + V+ G ++TL C A G P P I W +
Sbjct: 15 VPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGW 74
Query: 180 ------KPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSG 233
+ + GQ L I +G Y C AEN R ++V P++ +
Sbjct: 75 GQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQ-RDFHLLVLTPPSVLGAGAA 133
Query: 234 TVTPGRSGL---IRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQE 290
G +G ++C +GVP P EW K + + G + +Q +T ++V E
Sbjct: 134 QEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDE 193
Query: 291 HFGNYTCVAANKLGTTNASLPLN---PPSTAQYGITGSADVL 329
G Y CVA + G L PP+ TG V+
Sbjct: 194 --GRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVM 233
Score = 28.9 bits (63), Expect = 7.3
Identities = 25/95 (26%), Positives = 34/95 (35%), Gaps = 12/95 (12%)
Query: 47 NMMVRKGDTAVLRCYLEDGASKGA-WLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQI 105
+M VR GD LRC + WL + R S D SL +
Sbjct: 3035 DMTVRSGDDVALRCQATGEPTPTIEWLQAGQPL-----------RASRRLRTLPDGSLWL 3083
Query: 106 QNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPK 140
+NV+ D G Y C T + L V+ P+
Sbjct: 3084 ENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 3118
>gi|142976733 surface glycoprotein, Ig superfamily member [Homo
sapiens]
Length = 1264
Score = 85.9 bits (211), Expect = 5e-17
Identities = 72/247 (29%), Positives = 101/247 (40%), Gaps = 32/247 (12%)
Query: 98 KRDYS-LQIQNVDVTDDGPYTCSVQTQHTP-RTMQVHLTVQVPPKIYDISNDMTVNEGTN 155
+R YS L +VD D G Y+C + + + + V I D V+ G
Sbjct: 269 RRLYSHLATDSVDPADSGNYSCMAGNKSGDVKYVTYMVNVLEHASISKGLQDQIVSLGAT 328
Query: 156 VTLTCLATGKPEPSISWRH----ISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSF 211
V TC G P P+ +W H I PSA+ G L I G+T + G Y+C A+N + F
Sbjct: 329 VHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTAGNGLKISGVTVEDVGMYQCVADNGIGF 388
Query: 212 PDVRKVKVVVN---FAPTIQEIK-SGTVTPGRSGLIRCEGAGVPPPAFEWY--------- 258
+ N F P I S V G + C +G+P P WY
Sbjct: 389 MHSTGRLEIENDGGFKPVIITAPVSAKVADGDFVTLSCNASGLPVPVIRWYDSHGLITSH 448
Query: 259 -------KGEKKLFNGQQGIIIQ------NFSTRSILTVTNVTQEHFGNYTCVAANKLGT 305
K K + +G+ ++ + + S L + VTQEH G Y C AAN+ GT
Sbjct: 449 PSQVLRSKSRKSQLSRPEGLNLEPVYFVLSQAGASSLHIQAVTQEHAGKYICEAANEHGT 508
Query: 306 TNASLPL 312
T A L
Sbjct: 509 TQAEASL 515
Score = 59.7 bits (143), Expect = 4e-09
Identities = 57/223 (25%), Positives = 92/223 (41%), Gaps = 30/223 (13%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLT------VQVPPKIYDI-------SNDM 148
+LQI NV + D G Y C+ + P T Q+ + + P D+ S +
Sbjct: 175 NLQILNVSLEDKGSYKCAA---YNPVTHQLKVEPIGRKLLVSRPSSDDVHILHPTHSQAL 231
Query: 149 TVNEGTNVTLTCLATGKPEPSISW----RHISPSAKPFENGQYLDIYGITRDQAGEYECS 204
V + VTL C+ +G P P + W + I+P + +L + +G Y C
Sbjct: 232 AVLSRSPVTLECVVSGVPAPQVYWLKDGQDIAPGSNWRRLYSHLATDSVDPADSGNYSCM 291
Query: 205 AENDVSFPDVRKVKVVVN---FAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGE 261
A N DV+ V +VN A + ++ V+ G + C+ G P P W+
Sbjct: 292 AGNKSG--DVKYVTYMVNVLEHASISKGLQDQIVSLGATVHFTCDVHGNPAPNCTWFHNA 349
Query: 262 KKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 304
+ + + + N L ++ VT E G Y CVA N +G
Sbjct: 350 QPIHPSARHLTAGNG-----LKISGVTVEDVGMYQCVADNGIG 387
>gi|139948432 adlican [Homo sapiens]
Length = 2828
Score = 83.2 bits (204), Expect = 3e-16
Identities = 69/242 (28%), Positives = 106/242 (43%), Gaps = 18/242 (7%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHL--TVQVPPKIYDISNDMTVNEGTNVTLT 159
+L I+ V V D G Y C+ H M V L TVQ P + D+TV G + +
Sbjct: 1912 TLVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTVYLGDTIAME 1971
Query: 160 CLATGKPEPSISW----RHISPSAKPFE------NGQYLDIYGITRDQAGEYECSAENDV 209
CLA G P P ISW R + + P E + L I + G Y+C A N
Sbjct: 1972 CLAKGTPAPQISWIFPDRRVWQTVSPVEGRITLHENRTLSIKEASFSDRGVYKCVASN-A 2030
Query: 210 SFPDVRKVKVVVNFAPTI---QEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFN 266
+ D +++ V P + +++++ ++ PG S I C P P+ W G+
Sbjct: 2031 AGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVLGDGTQIR 2090
Query: 267 GQQGIIIQNF-STRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN-PPSTAQYGITG 324
Q + F L + N+ + G Y CVAAN +G+ ++ LN + A ITG
Sbjct: 2091 PSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLNVQRAAANARITG 2150
Query: 325 SA 326
++
Sbjct: 2151 TS 2152
Score = 66.2 bits (160), Expect = 4e-11
Identities = 78/307 (25%), Positives = 125/307 (40%), Gaps = 53/307 (17%)
Query: 48 MMVRKGDTAVLRCYLE-DGASKGAWLNRSS-IIFAGGDKWSVDPRVSISTLNKRDYSLQI 105
+ V GD + C + + K WL+ ++ +I +K+ + +D +L I
Sbjct: 2356 VQVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQI----------YQDGTLLI 2405
Query: 106 QNVDVTDDGPYTCSVQTQ--HTPRTMQVHLTVQVPPKIYDISNDM-TVNE----GTNVTL 158
Q +D G YTC V+ +T+ +H+ VQ PPKI N + TV E G+ +
Sbjct: 2406 QKAQRSDSGNYTCLVRNSAGEDRKTVWIHVNVQ-PPKINGNPNPITTVREIAAGGSRKLI 2464
Query: 159 TCLATGKPEPSISWRHISPSAKP----------FENGQYLDIYGITRDQAGEYECSAEND 208
C A G P P + W P NG LDI + + + + C A N+
Sbjct: 2465 DCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVHGNGS-LDIRSLRKSDSVQLVCMARNE 2523
Query: 209 VSFPDVRKVKVVVNFAPTIQEI------KSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEK 262
+ R + + P + I + T G + + C AG P P+ W
Sbjct: 2524 GG--EARLILQLTVLEPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWV---- 2577
Query: 263 KLFNG---QQGIIIQNFSTRS--ILTVTNVTQEHFGNYTCVAANKLGTT----NASLPLN 313
L NG Q G +Q F ++ +L ++ ++ G Y CVA N G T + + L
Sbjct: 2578 -LPNGTDLQSGQQLQRFYHKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLK 2636
Query: 314 PPSTAQY 320
P + QY
Sbjct: 2637 PEANKQY 2643
Score = 63.5 bits (153), Expect = 3e-10
Identities = 77/284 (27%), Positives = 121/284 (42%), Gaps = 40/284 (14%)
Query: 47 NMMVRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKW-SVDPRVSISTLNKRDYSLQI 105
++ V GDT + C +KG + S IF W +V P TL++ + +L I
Sbjct: 1959 DVTVYLGDTIAMECL-----AKGTPAPQISWIFPDRRVWQTVSPVEGRITLHE-NRTLSI 2012
Query: 106 QNVDVTDDGPYTCSVQTQHTPRTMQVHLTV-QVPPKIY-DISNDMTVNEGTNVTLTCLAT 163
+ +D G Y C ++ + L V +PP I+ + ++++ G ++ + C A
Sbjct: 2013 KEASFSDRGVYKCVASNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAK 2072
Query: 164 GKPEPSISW-----RHISPS------AKPFENGQYLDIYGITRDQAGEYECSAENDVSFP 212
P PS+ W I PS F NG L I + +G YEC A N V
Sbjct: 2073 AAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGT-LYIRNLAPKDSGRYECVAANLVGSA 2131
Query: 213 DVRKVKVVVNFAPTIQEIKSGT------VTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFN 266
R V++ V A I +GT V G + + C +G P P W K++ +
Sbjct: 2132 R-RTVQLNVQRAAANARI-TGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRMID 2189
Query: 267 GQQGIIIQNFSTR------SILTVTNVTQEHFGNYTCVAANKLG 304
+ +F +R L V +VT + G+Y CVA NK+G
Sbjct: 2190 A-----LFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVG 2228
Score = 61.2 bits (147), Expect = 1e-09
Identities = 75/281 (26%), Positives = 112/281 (39%), Gaps = 39/281 (13%)
Query: 50 VRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNK--RDYSLQIQN 107
VR G T L C AS W I++ K +D S + K + +L +++
Sbjct: 2158 VRYGGTLKLDC----SASGDPW---PRILWRLPSKRMIDALFSFDSRIKVFANGTLVVKS 2210
Query: 108 VDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPP-KI-YDISNDMTVNEGTNVTLTCLATGK 165
V D G Y C + + + + + V + P KI + ND V G ++ + C+ATG
Sbjct: 2211 VTDKDAGDYLCVARNKVGDDYVVLKVDVVMKPAKIEHKEENDHKVFYGGDLKVDCVATGL 2270
Query: 166 PEPSISWRHISPSA-----------------KPFENGQ-YLDIYGITRDQAGEYECSAEN 207
P P ISW S F NG Y + G+ + G+Y C AEN
Sbjct: 2271 PNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREE--GDYTCFAEN 2328
Query: 208 DVSFPDVR-KVKVVVNFAPTIQEIKSGTVTP-GRSGLIRCEGAGVPPPAFEWYKGEKKLF 265
V ++R +VKVV A + P G + CE G P P W K+
Sbjct: 2329 QVGKDEMRVRVKVVTAPATIRNKTYLAVQVPYGDVVTVACEAKGEPMPKVTWLSPTNKVI 2388
Query: 266 --NGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 304
+ ++ I Q+ L + + GNYTC+ N G
Sbjct: 2389 PTSSEKYQIYQD----GTLLIQKAQRSDSGNYTCLVRNSAG 2425
Score = 60.5 bits (145), Expect = 2e-09
Identities = 56/228 (24%), Positives = 88/228 (38%), Gaps = 20/228 (8%)
Query: 102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVP---PKIYD-ISNDMTVNEGTNVT 157
SL I+++ +D C + + + + LTV P P +D IS +T G ++
Sbjct: 2502 SLDIRSLRKSDSVQLVCMARNEGGEARLILQLTVLEPMEKPIFHDPISEKITAMAGHTIS 2561
Query: 158 LTCLATGKPEPSISWRHISPSAKPFENGQYLD-----------IYGITRDQAGEYECSAE 206
L C A G P PS+ W + P+ ++GQ L I G++ AG Y C A
Sbjct: 2562 LNCSAAGTPTPSLVW--VLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVDAGAYRCVAR 2619
Query: 207 NDVSFPDVRKVKVVVNFAPTIQEIKSGTVT--PGRSGLIRCEGAGVPPPAFEWYKGEKKL 264
N + R V + V P + V+ G + + C G F W
Sbjct: 2620 NAAGHTE-RLVSLKVGLKPEANKQYHNLVSIINGETLKLPCTPPGAGQGRFSWTLPNGMH 2678
Query: 265 FNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 312
G Q + + LTV + G Y C + G + S+P+
Sbjct: 2679 LEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPV 2726
Score = 53.5 bits (127), Expect = 3e-07
Identities = 58/228 (25%), Positives = 90/228 (39%), Gaps = 23/228 (10%)
Query: 97 NKRDYSLQIQNVDVTDDGPYTCSVQTQ--HTPRTMQVHLTVQVPPKIYDISNDMTVNEGT 154
+K D L I + D G Y C + HT R + + + ++ P N +++ G
Sbjct: 2595 HKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLK-PEANKQYHNLVSIINGE 2653
Query: 155 NVTLTCLATGKPEPSISWRHISPSAKPFENGQ------YLDIYGITRDQA-----GEYEC 203
+ L C G + SW P+ E Q LD +T +A G Y C
Sbjct: 2654 TLKLPCTPPGAGQGRFSWT--LPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVC 2711
Query: 204 SAENDVSFPDVRKVKVVV-NFAPTIQEIKSGTV--TPGRSGLIRCEGAGVPPPAFEWYKG 260
E + P V + V+V + P I + + PG + + C G+P W
Sbjct: 2712 RMETEYG-PSVTSIPVIVIAYPPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWELP 2770
Query: 261 EKK-LFNGQQGIIIQN--FSTRSILTVTNVTQEHFGNYTCVAANKLGT 305
+K L G Q + N + LT+ + TQ G Y C+A N LG+
Sbjct: 2771 DKSHLKAGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKCMAKNILGS 2818
Score = 51.2 bits (121), Expect = 1e-06
Identities = 57/236 (24%), Positives = 92/236 (38%), Gaps = 22/236 (9%)
Query: 84 KWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYD 143
+W + P + I LN+R + + V ++ Y+ ++ T+ T R + V + P
Sbjct: 430 EWVMQPSIDIQ-LNRRQSTAK--KVLLSYYTQYSQTISTKDT-RQARGRSWVMIEPS-GA 484
Query: 144 ISNDMTVNEGTNVTLTCLATGKPEPSISW----------RHISPSAK-PFENGQYLDIYG 192
+ D TV EG L+C PSI W P +K + +L I
Sbjct: 485 VQRDQTVLEGGPCQLSCNVKASESPSIFWVLPDGSILKAPMDDPDSKFSILSSGWLRIKS 544
Query: 193 ITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVT----PGRSGLIRCEGA 248
+ +G Y+C A+ V R V V+ +P+ Q + TVT PG S + C
Sbjct: 545 MEPSDSGLYQCIAQ--VRDEMDRMVYRVLVQSPSTQPAEKDTVTIGKNPGESVTLPCNAL 602
Query: 249 GVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 304
+P W +++ N L++ V G Y CVA N+ G
Sbjct: 603 AIPEAHLSWILPNRRIINDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQQG 658
Score = 48.9 bits (115), Expect = 7e-06
Identities = 44/187 (23%), Positives = 79/187 (42%), Gaps = 29/187 (15%)
Query: 148 MTVNEGTNVTLTCLATGKPEPSISWRHISPSA-----------KPFENGQYLDIYGITRD 196
++V T+ C ATGKP+P ++W +S A + +NG L I +
Sbjct: 1863 VSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKNGT-LVIRKVQVQ 1921
Query: 197 QAGEYECSAENDVSFPDVRKVKVVVNFAPTIQE-------IKSGTVTPGRSGLIRCEGAG 249
G+Y C+A N ++VV + T+Q+ + TV G + + C G
Sbjct: 1922 DRGQYMCTASNLHGLD-----RMVVLLSVTVQQPQILASHYQDVTVYLGDTIAMECLAKG 1976
Query: 250 VPPPAFEWYKGEKKLF---NGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTT 306
P P W +++++ + +G I L++ + G Y CVA+N G
Sbjct: 1977 TPAPQISWIFPDRRVWQTVSPVEGRI--TLHENRTLSIKEASFSDRGVYKCVASNAAGAD 2034
Query: 307 NASLPLN 313
+ ++ L+
Sbjct: 2035 SLAIRLH 2041
>gi|40255157 leucine-rich repeats and immunoglobulin-like domains 3
isoform 2 [Homo sapiens]
Length = 1119
Score = 82.0 bits (201), Expect = 7e-16
Identities = 50/221 (22%), Positives = 91/221 (41%), Gaps = 13/221 (5%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQH-TPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCL 161
L+++ V+ +G Y C + + +++ LTV + P D+T+ G L C
Sbjct: 566 LRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECA 625
Query: 162 ATGKPEPSISWRHISPSAKPFENGQYLD---------IYGITRDQAGEYECSAENDVSFP 212
A G P P I+W+ + P + + I + + G Y C+A+N
Sbjct: 626 AVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSI 685
Query: 213 DVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGII 272
V+ ++ + TVT G + +++C G PPP W K + L ++
Sbjct: 686 SANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFF 745
Query: 273 IQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 313
+ +L + + G YTC +N LGT ++ L+
Sbjct: 746 A---AGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLS 783
>gi|209862903 leucine-rich repeats and immunoglobulin-like domains 3
isoform 1 [Homo sapiens]
Length = 1059
Score = 82.0 bits (201), Expect = 7e-16
Identities = 50/221 (22%), Positives = 91/221 (41%), Gaps = 13/221 (5%)
Query: 103 LQIQNVDVTDDGPYTCSVQTQH-TPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCL 161
L+++ V+ +G Y C + + +++ LTV + P D+T+ G L C
Sbjct: 506 LRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECA 565
Query: 162 ATGKPEPSISWRHISPSAKPFENGQYLD---------IYGITRDQAGEYECSAENDVSFP 212
A G P P I+W+ + P + + I + + G Y C+A+N
Sbjct: 566 AVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSI 625
Query: 213 DVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGII 272
V+ ++ + TVT G + +++C G PPP W K + L ++
Sbjct: 626 SANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFF 685
Query: 273 IQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 313
+ +L + + G YTC +N LGT ++ L+
Sbjct: 686 A---AGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLS 723
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,632,796
Number of Sequences: 37866
Number of extensions: 667716
Number of successful extensions: 5908
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 259
Number of HSP's successfully gapped in prelim test: 225
Number of HSP's that attempted gapping in prelim test: 1902
Number of HSP's gapped (non-prelim): 2211
length of query: 354
length of database: 18,247,518
effective HSP length: 103
effective length of query: 251
effective length of database: 14,347,320
effective search space: 3601177320
effective search space used: 3601177320
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.