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Search of human proteins with 62243248
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62243248 insulin-like growth factor binding protein 3
isoform a precursor [Homo sapiens]
(297 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62243248 insulin-like growth factor binding protein 3 isoform... 625 e-179
gi|62243068 insulin-like growth factor binding protein 3 isoform... 605 e-173
gi|10834982 insulin-like growth factor binding protein 5 [Homo s... 232 3e-61
gi|62243290 insulin-like growth factor binding protein 4 precurs... 152 4e-37
gi|55925576 insulin-like growth factor binding protein 2, 36kDa ... 149 3e-36
gi|11321593 insulin-like growth factor binding protein 6 [Homo s... 132 4e-31
gi|4504615 insulin-like growth factor binding protein 1 precurso... 121 6e-28
gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens] 60 2e-09
gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteo... 55 7e-08
gi|93141003 testican 3 isoform 1 [Homo sapiens] 52 5e-07
gi|93141001 testican 3 isoform 2 [Homo sapiens] 52 5e-07
gi|7662036 sparc/osteonectin, cwcv and kazal-like domains proteo... 52 5e-07
gi|56090548 insulin-like growth factor binding protein-like 1 [H... 51 1e-06
gi|22129776 HtrA serine peptidase 3 [Homo sapiens] 49 5e-06
gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens] 48 9e-06
gi|144953895 nidogen 2 precursor [Homo sapiens] 48 1e-05
gi|4504619 insulin-like growth factor binding protein 7 [Homo sa... 47 3e-05
gi|115298674 nidogen 1 precursor [Homo sapiens] 46 5e-05
gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens] 45 6e-05
gi|5901946 endothelial cell-specific molecule 1 isoform a precur... 45 1e-04
gi|208022668 endothelial cell-specific molecule 1 isoform b prec... 45 1e-04
gi|78190498 secreted modular calcium-binding protein 1 isoform 1... 43 3e-04
gi|11545873 secreted modular calcium-binding protein 1 isoform 2... 43 3e-04
gi|19923632 Kazal-type serine peptidase inhibitor domain 1 precu... 41 0.001
gi|55770862 thyroglobulin [Homo sapiens] 41 0.001
gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] 40 0.002
gi|4507923 WNT1 inducible signaling pathway protein 2 precursor ... 38 0.009
gi|218505670 epithelial cell adhesion molecule precursor [Homo s... 36 0.036
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo... 36 0.036
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo... 36 0.036
>gi|62243248 insulin-like growth factor binding protein 3 isoform a
precursor [Homo sapiens]
Length = 297
Score = 625 bits (1613), Expect = e-179
Identities = 297/297 (100%), Positives = 297/297 (100%)
Query: 1 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE 60
MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE
Sbjct: 1 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE 60
Query: 61 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV 120
LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
Sbjct: 61 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV 120
Query: 121 SRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII 180
SRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII
Sbjct: 121 SRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII 180
Query: 181 IKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG 240
IKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG
Sbjct: 181 IKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG 240
Query: 241 VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK 297
VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
Sbjct: 241 VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK 297
>gi|62243068 insulin-like growth factor binding protein 3 isoform b
precursor [Homo sapiens]
Length = 291
Score = 605 bits (1560), Expect = e-173
Identities = 291/297 (97%), Positives = 291/297 (97%), Gaps = 6/297 (2%)
Query: 1 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE 60
MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE
Sbjct: 1 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE 60
Query: 61 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV 120
LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
Sbjct: 61 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV 120
Query: 121 SRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII 180
SRLRAYLLPAPPAPG NASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII
Sbjct: 121 SRLRAYLLPAPPAPG------NASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII 174
Query: 181 IKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG 240
IKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG
Sbjct: 175 IKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG 234
Query: 241 VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK 297
VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
Sbjct: 235 VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK 291
>gi|10834982 insulin-like growth factor binding protein 5 [Homo
sapiens]
Length = 272
Score = 232 bits (591), Expect = 3e-61
Identities = 123/282 (43%), Positives = 157/282 (55%), Gaps = 40/282 (14%)
Query: 8 LWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGC 67
L A L LL GP + LG V CEPCD +AL+ C P P C ELV+EPGC
Sbjct: 3 LLTAVLLLLAAYAGP--------AQSLGSFVHCEPCDEKALSMCPPSPLGC-ELVKEPGC 53
Query: 68 GCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYL 127
GCC+TCAL+EGQ CG+YTERC GLRC P DE +PL ALL GRG+C+N +
Sbjct: 54 GCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYRE----- 108
Query: 128 LPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSS-THRVSDPK-FHPLHSKIIIIKKGH 185
+ + +R + E P+ S PK F P H++I +K
Sbjct: 109 -----------------QVKIERDSREHEEPTTSEMAEETYSPKIFRPKHTRISELKAEA 151
Query: 186 AKDSQRYKVDYESQSTDTQNFSS-------ESKRETEYGPCRREMEDTLNHLKFLNVLSP 238
K +R K+ +N + E ++E+E GPCRR ME +L LK + P
Sbjct: 152 VKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKASPRMVP 211
Query: 239 RGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPG 280
R V++PNCD+KGFYK+KQC+PS+GRKRG CWCVDKYG LPG
Sbjct: 212 RAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPG 253
>gi|62243290 insulin-like growth factor binding protein 4 precursor
[Homo sapiens]
Length = 258
Score = 152 bits (383), Expect = 4e-37
Identities = 93/270 (34%), Positives = 121/270 (44%), Gaps = 42/270 (15%)
Query: 31 SAGLGP-----VVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCGIYT 85
+AG GP + C PC LA+C PP C ELVREPGCGCC TCAL G PCG+YT
Sbjct: 13 AAGPGPSLGDEAIHCPPCSEEKLARCRPPVG-CEELVREPGCGCCATCALGLGMPCGVYT 71
Query: 86 ERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGEPPAPGNASE 145
RCGSGLRC P +PL L+ G+G+C+ + + ++ L P+ G+ P +
Sbjct: 72 PRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQPSDKDEGDHPNNSFSPC 131
Query: 146 SEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQN 205
S DR ++K AK R
Sbjct: 132 SAHDRRC----------------------------LQKHFAKIRDR---STSGGKMKVNG 160
Query: 206 FSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVH---IPNCDKKGFYKKKQCRPSKG 262
E R G C+ E+ L L + ++ IPNCD+ G + KQC P+
Sbjct: 161 APREDARPVPQGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALD 220
Query: 263 RKRGFCWCVD-KYGQPLP-GYTTKGKEDVH 290
+RG CWCVD K G LP G KG+ D H
Sbjct: 221 GQRGKCWCVDRKTGVKLPGGLEPKGELDCH 250
>gi|55925576 insulin-like growth factor binding protein 2, 36kDa
[Homo sapiens]
Length = 328
Score = 149 bits (376), Expect = 3e-36
Identities = 99/312 (31%), Positives = 138/312 (44%), Gaps = 52/312 (16%)
Query: 13 LTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAV--------------- 57
L LL+LL G A G A + RC PC LA C PPP
Sbjct: 21 LPLLLLLLG---ASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMP 77
Query: 58 CAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNA 117
CAELVREPGCGCC CA EG+ CG+YT RCG GLRC P P PLQAL+ G G C
Sbjct: 78 CAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEKR 137
Query: 118 SAVSRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRV----SDPKFHP 173
+P +++ +D S G + V ST + P
Sbjct: 138 RDAE--------------YGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKP 183
Query: 174 LHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETE----YGPCRREMEDTLNH 229
L S + + K +++++ + + E ++ PC++E++ L
Sbjct: 184 LKSGMKELAVFREKVTEQHR---QMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLER 240
Query: 230 LKFLNVLSPRG-------VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVD-KYGQPLPGY 281
+ + + RG +HIPNCDK G Y KQC+ S +RG CWCV+ G+ + G
Sbjct: 241 ISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGA 300
Query: 282 -TTKGKEDVHCY 292
T +G + H +
Sbjct: 301 PTIRGDPECHLF 312
>gi|11321593 insulin-like growth factor binding protein 6 [Homo
sapiens]
Length = 240
Score = 132 bits (332), Expect = 4e-31
Identities = 82/254 (32%), Positives = 112/254 (44%), Gaps = 50/254 (19%)
Query: 29 ASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLT--CALSEGQPCGIYTE 86
A+S G G + RC C A C P V E P GC C EGQ CG+YT
Sbjct: 19 AASPG-GALARCPGCGQGVQAGC-PGGCVEEEDGGSPAEGCAEAEGCLRREGQECGVYTP 76
Query: 87 RCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGEPPAPGNASES 146
C GL+C P D+ PL+ALL GRG C+ P PA +
Sbjct: 77 NCAPGLQCHPPKDDEAPLRALLLGRGRCL------------------PARAPAVAEENPK 118
Query: 147 EEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNF 206
E AG+ V+ + +P ST
Sbjct: 119 ESKPQAGTARPQDVNRRDQQRNP----------------------------GTSTTPSQP 150
Query: 207 SSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRG 266
+S ++TE GPCRR ++ L L+ + +++PNCD +GFY+K+QCR S+G++RG
Sbjct: 151 NSAGVQDTEMGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRG 210
Query: 267 FCWCVDKYGQPLPG 280
CWCVD+ G+ LPG
Sbjct: 211 PCWCVDRMGKSLPG 224
>gi|4504615 insulin-like growth factor binding protein 1 precursor
[Homo sapiens]
Length = 259
Score = 121 bits (304), Expect = 6e-28
Identities = 82/248 (33%), Positives = 109/248 (43%), Gaps = 41/248 (16%)
Query: 39 RCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSP 98
+C PC A LA C P A C+E+ R GCGCC CAL G CG+ T RC GL C+ P
Sbjct: 29 QCAPCSAEKLALCPPVSASCSEVTRSAGCGCCPMCALPLGAACGVATARCARGLSCRALP 88
Query: 99 DEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESP 158
E +PL AL G+G CV S S AP A AGS ESP
Sbjct: 89 GEQQPLHALTRGQGACVQESDAS--------APHAA----------------EAGSPESP 124
Query: 159 -SVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQST-DTQNFSSESKRETEY 216
S T FH + A + + + +++ ST D + +
Sbjct: 125 ESTEITEEELLDNFHLM-----------APSEEDHSILWDAISTYDGSKALHVTNIKKWK 173
Query: 217 GPCRREMEDTLNHLKFLNVLSPRGV---HIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDK 273
PCR E+ + L S + ++PNC+K GFY +QC S + G CWCV
Sbjct: 174 EPCRIELYRVVESLAKAQETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLCWCVYP 233
Query: 274 Y-GQPLPG 280
+ G+ +PG
Sbjct: 234 WNGKRIPG 241
>gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens]
Length = 480
Score = 60.5 bits (145), Expect = 2e-09
Identities = 46/121 (38%), Positives = 54/121 (44%), Gaps = 22/121 (18%)
Query: 10 AAALTLLVLLRGPP----VARAGASSA-GLGPVVRCEPCDARALAQCAPPPAVCAELVRE 64
AA L LL+LL P ++RAG S+ G RCEP A+C P P C
Sbjct: 6 AALLPLLLLLLAAPASAQLSRAGRSAPLAAGCPDRCEP------ARCPPQPEHCEGGRAR 59
Query: 65 PGCGCCLTCALSEGQPCGIYTERCGSGLRC------QPSPDEARPLQALLDGRGLCVNAS 118
CGCC C EG CG+ CG GL+C S R QA GLCV AS
Sbjct: 60 DACGCCEVCGAPEGAACGLQEGPCGEGLQCVVPFGVPASATVRRRAQA-----GLCVCAS 114
Query: 119 A 119
+
Sbjct: 115 S 115
>gi|4759164 sparc/osteonectin, cwcv and kazal-like domains
proteoglycan 1 precursor [Homo sapiens]
Length = 439
Score = 55.1 bits (131), Expect = 7e-08
Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 7/68 (10%)
Query: 218 PCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQP 277
PC+ EM K ++L G IP C+++G+YK QC S G+ CWCVDKYG
Sbjct: 312 PCQNEMNRIQKLSKGKSLL---GAFIPRCNEEGYYKATQCHGSTGQ----CWCVDKYGNE 364
Query: 278 LPGYTTKG 285
L G +G
Sbjct: 365 LAGSRKQG 372
>gi|93141003 testican 3 isoform 1 [Homo sapiens]
Length = 433
Score = 52.4 bits (124), Expect = 5e-07
Identities = 28/71 (39%), Positives = 36/71 (50%), Gaps = 7/71 (9%)
Query: 218 PCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQP 277
PC+ E+ N K V G +IP CD+ G+YK QC S G+ CWCVD+YG
Sbjct: 313 PCQTELS---NIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQ----CWCVDRYGNE 365
Query: 278 LPGYTTKGKED 288
+ G G D
Sbjct: 366 VMGSRINGVAD 376
>gi|93141001 testican 3 isoform 2 [Homo sapiens]
Length = 436
Score = 52.4 bits (124), Expect = 5e-07
Identities = 28/71 (39%), Positives = 36/71 (50%), Gaps = 7/71 (9%)
Query: 218 PCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQP 277
PC+ E+ N K V G +IP CD+ G+YK QC S G+ CWCVD+YG
Sbjct: 316 PCQTELS---NIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQ----CWCVDRYGNE 368
Query: 278 LPGYTTKGKED 288
+ G G D
Sbjct: 369 VMGSRINGVAD 379
>gi|7662036 sparc/osteonectin, cwcv and kazal-like domains
proteoglycan (testican) 2 isoform 2 [Homo sapiens]
Length = 424
Score = 52.4 bits (124), Expect = 5e-07
Identities = 23/49 (46%), Positives = 29/49 (59%), Gaps = 4/49 (8%)
Query: 240 GVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKED 288
G+ IP+CD+ G+Y+K QC S G CWCVD+ G L G T G D
Sbjct: 331 GIFIPSCDEDGYYRKMQCDQSSGD----CWCVDQLGLELTGTRTHGSPD 375
>gi|56090548 insulin-like growth factor binding protein-like 1 [Homo
sapiens]
Length = 278
Score = 51.2 bits (121), Expect = 1e-06
Identities = 42/115 (36%), Positives = 51/115 (44%), Gaps = 10/115 (8%)
Query: 5 RPTLWAAALTLLVLLRGPPVARA-GASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVR 63
R +L L LL+L PP++ + G G G +C PC AP PA +
Sbjct: 3 RLSLLLPLLLLLLLPLLPPLSPSLGIRDVG-GRRPKCGPCRPEGCPAPAPCPAPGISALD 61
Query: 64 EPGCGCCLTCALSEGQPCGIYT-ERCGSGLRCQPSPDEARPLQALLDGRGLCVNA 117
E CGCC C +EG CG RCG GL C A P +G GLCV A
Sbjct: 62 E--CGCCARCLGAEGASCGGRAGGRCGPGLVCASQAAGAAP-----EGTGLCVCA 109
>gi|22129776 HtrA serine peptidase 3 [Homo sapiens]
Length = 453
Score = 48.9 bits (115), Expect = 5e-06
Identities = 33/88 (37%), Positives = 35/88 (39%), Gaps = 18/88 (20%)
Query: 8 LWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGC 67
L AAL L L R PP A PC AR P P V + C
Sbjct: 6 LLLAALAALALAREPPAA----------------PCPARCDVSRCPSPRCPGGYVPDL-C 48
Query: 68 GCCLTCALSEGQPC-GIYTERCGSGLRC 94
CCL CA SEG+PC G CG L C
Sbjct: 49 NCCLVCAASEGEPCGGPLDSPCGESLEC 76
>gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens]
Length = 457
Score = 48.1 bits (113), Expect = 9e-06
Identities = 43/153 (28%), Positives = 65/153 (42%), Gaps = 22/153 (14%)
Query: 137 PPAPGNASESEEDRSA-GSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKD-SQRYKV 194
P PG+ +E R G S + S D L ++ +G +D + RY
Sbjct: 151 PRCPGSVNEKLPQREGTGKTVSLQIFSVLNSDDAAAPALETQ----PQGDEEDIASRYPT 206
Query: 195 DYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG--VHIPNCDKKGFY 252
+ Q QN ++++ + C +E + L K P+ V IP C G Y
Sbjct: 207 LWTEQVKSRQNKTNKNSVSS----CDQEHQSALEEAK-----QPKNDNVVIPECAHGGLY 257
Query: 253 KKKQCRPSKGRKRGFCWCV-DKYGQPLPGYTTK 284
K QC PS G+CWCV G+P+PG +T+
Sbjct: 258 KPVQCHPS----TGYCWCVLVDTGRPIPGTSTR 286
Score = 38.1 bits (87), Expect = 0.009
Identities = 40/163 (24%), Positives = 59/163 (36%), Gaps = 35/163 (21%)
Query: 123 LRAYLLPAPPAPGEPPAPGNASESEEDRS-----AGSVESPSVSSTHRVSDPKFHPLHSK 177
L A LLP PA + ++D+ AGS + P +S R +
Sbjct: 11 LLAGLLPPVPAQKFSALTFLRVDQDKDKDCSLDCAGSPQKPLCASDGRTFLSRCE----- 65
Query: 178 IIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLS 237
++ KD Q ++ Y D +E K E R+E +
Sbjct: 66 ---FQRAKCKDPQ-LEIAYRGNCKDVSRCVAERKYTQEQA--RKEFQQ------------ 107
Query: 238 PRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPG 280
V IP C+ G Y + QC G +CWCV G+P+ G
Sbjct: 108 ---VFIPECNDDGTYSQVQCHSYTG----YCWCVTPNGRPISG 143
>gi|144953895 nidogen 2 precursor [Homo sapiens]
Length = 1375
Score = 47.8 bits (112), Expect = 1e-05
Identities = 23/51 (45%), Positives = 27/51 (52%), Gaps = 5/51 (9%)
Query: 242 HIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPG-YTTKGKEDVHC 291
HIP CD++G + QC S G FCWCVD G +PG T G HC
Sbjct: 959 HIPQCDEQGNFLPLQCHGSTG----FCWCVDPDGHEVPGTQTPPGSTPPHC 1005
Score = 38.9 bits (89), Expect = 0.006
Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 9/63 (14%)
Query: 219 CRREMEDTLNHLKFLNVLSPRG-VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQP 277
C R E+ L H +PR ++P CD G + QC K FCWCVDK G+
Sbjct: 1019 CERWRENLLEHYGG----TPRDDQYVPQCDDLGHFIPLQCHG----KSDFCWCVDKDGRE 1070
Query: 278 LPG 280
+ G
Sbjct: 1071 VQG 1073
>gi|4504619 insulin-like growth factor binding protein 7 [Homo
sapiens]
Length = 282
Score = 46.6 bits (109), Expect = 3e-05
Identities = 33/94 (35%), Positives = 41/94 (43%), Gaps = 18/94 (19%)
Query: 8 LWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAP-PPAVCAELVREPG 66
L AA L LL+L P++ + +S C PC+ A C P PP C
Sbjct: 11 LGAAGLLLLLL----PLSSSSSSDT-------CGPCEP---ASCPPLPPLGCLLGETRDA 56
Query: 67 CGCCLTCALSEGQPC---GIYTERCGSGLRCQPS 97
CGCC CA EG+PC G C G+ C S
Sbjct: 57 CGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKS 90
>gi|115298674 nidogen 1 precursor [Homo sapiens]
Length = 1247
Score = 45.8 bits (107), Expect = 5e-05
Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 4/56 (7%)
Query: 238 PRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYS 293
P G+ +P CD G Y QC S G+CWCVD+ G+ + G T+ C S
Sbjct: 870 PPGLFVPECDAHGHYAPTQCHGS----TGYCWCVDRDGREVEGTRTRPGMTPPCLS 921
>gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens]
Length = 357
Score = 45.4 bits (106), Expect = 6e-05
Identities = 27/70 (38%), Positives = 31/70 (44%), Gaps = 5/70 (7%)
Query: 34 LGPVVRCEPCDARALAQCAPPPAVCAELVRE--PGCGCCLTCALSEGQPCGIYTERC--G 89
LG V + C + +C P CA VR GC CCL CA G+ C E C
Sbjct: 26 LGQVAATQRCPPQCPGRCPATPPTCAPGVRAVLDGCSCCLVCARQRGESCS-DLEPCDES 84
Query: 90 SGLRCQPSPD 99
SGL C S D
Sbjct: 85 SGLYCDRSAD 94
>gi|5901946 endothelial cell-specific molecule 1 isoform a precursor
[Homo sapiens]
Length = 184
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 10/63 (15%)
Query: 43 CDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPC-----GIYTERCGSGLRCQPS 97
CD+ ++C P C V + CGCC CA G+ C G+ +CG GLRCQPS
Sbjct: 32 CDS---SECKSSPR-CKRTVLDD-CGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPS 86
Query: 98 PDE 100
E
Sbjct: 87 NGE 89
>gi|208022668 endothelial cell-specific molecule 1 isoform b
precursor [Homo sapiens]
Length = 134
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 10/63 (15%)
Query: 43 CDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPC-----GIYTERCGSGLRCQPS 97
CD+ ++C P C V + CGCC CA G+ C G+ +CG GLRCQPS
Sbjct: 32 CDS---SECKSSPR-CKRTVLDD-CGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPS 86
Query: 98 PDE 100
E
Sbjct: 87 NGE 89
>gi|78190498 secreted modular calcium-binding protein 1 isoform 1
[Homo sapiens]
Length = 435
Score = 43.1 bits (100), Expect = 3e-04
Identities = 26/68 (38%), Positives = 35/68 (51%), Gaps = 10/68 (14%)
Query: 219 CRREMEDTLNHLKFLNVLSPR-GVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCV-DKYGQ 276
C +E + L + +PR G+ IP C G YK QC S G+CWCV G+
Sbjct: 227 CDQERQSALEEAQ----QNPREGIVIPECAPGGLYKPVQCHQS----TGYCWCVLVDTGR 278
Query: 277 PLPGYTTK 284
PLPG +T+
Sbjct: 279 PLPGTSTR 286
Score = 40.0 bits (92), Expect = 0.002
Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 8/79 (10%)
Query: 219 CRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPL 278
CR E L K V +P C + G + + QC G +CWCV G+P+
Sbjct: 95 CRLERAQALEQAK----KPQEAVFVPECGEDGSFTQVQCHTYTG----YCWCVTPDGKPI 146
Query: 279 PGYTTKGKEDVHCYSMQSK 297
G + + K V S+ K
Sbjct: 147 SGSSVQNKTPVCSGSVTDK 165
>gi|11545873 secreted modular calcium-binding protein 1 isoform 2
[Homo sapiens]
Length = 434
Score = 43.1 bits (100), Expect = 3e-04
Identities = 26/68 (38%), Positives = 35/68 (51%), Gaps = 10/68 (14%)
Query: 219 CRREMEDTLNHLKFLNVLSPR-GVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCV-DKYGQ 276
C +E + L + +PR G+ IP C G YK QC S G+CWCV G+
Sbjct: 227 CDQERQSALEEAQ----QNPREGIVIPECAPGGLYKPVQCHQS----TGYCWCVLVDTGR 278
Query: 277 PLPGYTTK 284
PLPG +T+
Sbjct: 279 PLPGTSTR 286
Score = 40.0 bits (92), Expect = 0.002
Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 8/79 (10%)
Query: 219 CRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPL 278
CR E L K V +P C + G + + QC G +CWCV G+P+
Sbjct: 95 CRLERAQALEQAK----KPQEAVFVPECGEDGSFTQVQCHTYTG----YCWCVTPDGKPI 146
Query: 279 PGYTTKGKEDVHCYSMQSK 297
G + + K V S+ K
Sbjct: 147 SGSSVQNKTPVCSGSVTDK 165
>gi|19923632 Kazal-type serine peptidase inhibitor domain 1
precursor [Homo sapiens]
Length = 304
Score = 41.2 bits (95), Expect = 0.001
Identities = 31/97 (31%), Positives = 38/97 (39%), Gaps = 18/97 (18%)
Query: 13 LTLLVLLRGPPVARAGASSAG---------LGPVVRCEPCDARALAQCAPPPAVCAELVR 63
L LLV+L PP + L C PC +CA P A VR
Sbjct: 17 LLLLVVLTPPPTGARPSPGPDYLRRGWMRLLAEGEGCAPCRPE---ECAAPRGCLAGRVR 73
Query: 64 EPGCGCCLTCALSEGQPCGI-----YTERCGSGLRCQ 95
+ CGCC CA EGQ C + + CG L C+
Sbjct: 74 D-ACGCCWECANLEGQLCDLDPSAHFYGHCGEQLECR 109
>gi|55770862 thyroglobulin [Homo sapiens]
Length = 2768
Score = 40.8 bits (94), Expect = 0.001
Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 6/49 (12%)
Query: 237 SPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKG 285
+P + +P+C +G Y+ QC G CWCV+ +G+ LPG +G
Sbjct: 611 TPERLFVPSCTTEGSYEDVQCFS------GECWCVNSWGKELPGSRVRG 653
Score = 38.1 bits (87), Expect = 0.009
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 4/44 (9%)
Query: 240 GVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTT 283
G ++P CD G ++ QC G CWCVD+ G +PG T
Sbjct: 1025 GPYMPQCDAFGSWEPVQCHAGTGH----CWCVDEKGGFIPGSLT 1064
Score = 37.0 bits (84), Expect = 0.021
Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 6/55 (10%)
Query: 242 HIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQS 296
++P+C + G Y+ QC+ G CWCVD G+ + G +G E C QS
Sbjct: 315 YVPSCRRNGDYQAVQCQTE-----GPCWCVDAQGKEMHGTRQQG-EPPSCAEGQS 363
Score = 32.3 bits (72), Expect = 0.52
Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 8/64 (12%)
Query: 219 CRREMEDTLNHLKFLNVLSPRG--VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQ 276
C + E ++ L P G + +P C +G + QC S+ C+CVD GQ
Sbjct: 658 CPTDCEKQRARMQSLMGSQPAGSTLFVPACTSEGHFLPVQCFNSE------CYCVDAEGQ 711
Query: 277 PLPG 280
+PG
Sbjct: 712 AIPG 715
Score = 30.0 bits (66), Expect = 2.6
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 5/52 (9%)
Query: 242 HIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYS 293
++P C + G ++ QC+ + GR CWCV G + G G+ V C S
Sbjct: 48 YVPQCAEDGSFQTVQCQ-NDGRS---CWCVGANGSEVLGSRQPGR-PVACLS 94
Score = 30.0 bits (66), Expect = 2.6
Identities = 14/45 (31%), Positives = 20/45 (44%), Gaps = 4/45 (8%)
Query: 242 HIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGK 286
++P C G Y QC + + CWCVD G + G G+
Sbjct: 116 YLPQCQDSGDYAPVQCDVQQVQ----CWCVDAEGMEVYGTRQLGR 156
Score = 28.1 bits (61), Expect = 9.7
Identities = 14/45 (31%), Positives = 22/45 (48%), Gaps = 5/45 (11%)
Query: 242 HIPNCDKK-GFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKG 285
++P C + G + QC ++G CWCV G+ +PG G
Sbjct: 1165 YVPACRAEDGGFSPVQCDQAQGS----CWCVMDSGEEVPGTRVTG 1205
>gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]
Length = 1036
Score = 40.4 bits (93), Expect = 0.002
Identities = 32/95 (33%), Positives = 41/95 (43%), Gaps = 20/95 (21%)
Query: 8 LWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGC 67
L + L LL+LL AR+G + + C PCD + P C + + C
Sbjct: 16 LLVSLLGLLLLL-----ARSGTRA------LVCLPCDESKCEE----PRNCPGSIVQGVC 60
Query: 68 GCCLTCALSEGQPC----GIYTERCGSGLRCQPSP 98
GCC TCA + C GIY C GLRC P
Sbjct: 61 GCCYTCASQRNESCGGTFGIY-GTCDRGLRCVIRP 94
>gi|4507923 WNT1 inducible signaling pathway protein 2 precursor
[Homo sapiens]
Length = 250
Score = 38.1 bits (87), Expect = 0.009
Identities = 20/60 (33%), Positives = 25/60 (41%), Gaps = 1/60 (1%)
Query: 38 VRCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCG-IYTERCGSGLRCQP 96
VR + C PP + GCGCC CA G+PC ++ GL CQP
Sbjct: 21 VRTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVCQP 80
>gi|218505670 epithelial cell adhesion molecule precursor [Homo
sapiens]
Length = 314
Score = 36.2 bits (82), Expect = 0.036
Identities = 14/36 (38%), Positives = 21/36 (58%), Gaps = 5/36 (13%)
Query: 240 GVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYG 275
G++ P+CD+ G +K KQC + CWCV+ G
Sbjct: 93 GLYDPDCDESGLFKAKQCNGT-----SMCWCVNTAG 123
>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
sapiens]
Length = 870
Score = 36.2 bits (82), Expect = 0.036
Identities = 48/168 (28%), Positives = 62/168 (36%), Gaps = 29/168 (17%)
Query: 20 RGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVC-----AELVREPGCGCCLTCA 74
R P V A + PV P A + P PA A V PG A
Sbjct: 576 RDPEVPTVPAEAPAPSPVPLTTPASAE---EAIPLPASSDSERSASSVEGPGGALYARVA 632
Query: 75 LSEGQPCGIYTERCGSGL------RCQPSPDEA-RPLQALLDGRGLCVNASAVSRLRAYL 127
E +P E G L R P PD A +P + + G+ +A+A R
Sbjct: 633 RREARPARARGEIGGLSLSPSPERRKPPPPDPATKPKVSWIHGKH---SAAAAGRA---- 685
Query: 128 LPAPPAPGEP--PAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHP 173
P+PP PG P+P + D+SA +VE S R DP P
Sbjct: 686 -PSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGS----PRTRDPTPRP 728
>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
sapiens]
Length = 865
Score = 36.2 bits (82), Expect = 0.036
Identities = 48/168 (28%), Positives = 62/168 (36%), Gaps = 29/168 (17%)
Query: 20 RGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVC-----AELVREPGCGCCLTCA 74
R P V A + PV P A + P PA A V PG A
Sbjct: 571 RDPEVPTVPAEAPAPSPVPLTTPASAE---EAIPLPASSDSERSASSVEGPGGALYARVA 627
Query: 75 LSEGQPCGIYTERCGSGL------RCQPSPDEA-RPLQALLDGRGLCVNASAVSRLRAYL 127
E +P E G L R P PD A +P + + G+ +A+A R
Sbjct: 628 RREARPARARGEIGGLSLSPSPERRKPPPPDPATKPKVSWIHGKH---SAAAAGRA---- 680
Query: 128 LPAPPAPGEP--PAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHP 173
P+PP PG P+P + D+SA +VE S R DP P
Sbjct: 681 -PSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGS----PRTRDPTPRP 723
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,539,238
Number of Sequences: 37866
Number of extensions: 805906
Number of successful extensions: 6604
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 171
Number of HSP's that attempted gapping in prelim test: 6156
Number of HSP's gapped (non-prelim): 587
length of query: 297
length of database: 18,247,518
effective HSP length: 102
effective length of query: 195
effective length of database: 14,385,186
effective search space: 2805111270
effective search space used: 2805111270
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.