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Search of human proteins with 13449287
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13449287 NG3 protein [Homo sapiens]
(293 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13449287 NG3 protein [Homo sapiens] 623 e-179
gi|41393583 EGF-like-domain, multiple 7 [Homo sapiens] 160 1e-39
gi|7705889 EGF-like-domain, multiple 7 [Homo sapiens] 160 1e-39
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 92 4e-19
gi|13124888 epidermal growth factor-like protein 6 precursor [Ho... 79 4e-15
gi|75709198 nephronectin [Homo sapiens] 78 1e-14
gi|66346695 fibrillin 2 precursor [Homo sapiens] 69 6e-12
gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] 68 1e-11
gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] 67 1e-11
gi|56237021 fibrillin 3 precursor [Homo sapiens] 65 9e-11
gi|55770876 notch4 preproprotein [Homo sapiens] 64 2e-10
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 64 2e-10
gi|148886654 polydom [Homo sapiens] 62 5e-10
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 62 8e-10
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 62 8e-10
gi|4557679 jagged 1 precursor [Homo sapiens] 61 1e-09
gi|189491647 fibulin 7 isoform 2 [Homo sapiens] 61 1e-09
gi|134244285 Notch homolog 3 [Homo sapiens] 61 1e-09
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 61 1e-09
gi|24041035 notch 2 preproprotein [Homo sapiens] 60 2e-09
gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] 60 2e-09
gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] 60 2e-09
gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] 60 2e-09
gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] 60 2e-09
gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] 60 2e-09
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 60 2e-09
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 60 2e-09
gi|4506121 protein Z, vitamin K-dependent plasma glycoprotein [H... 60 3e-09
gi|24430141 fibrillin 1 precursor [Homo sapiens] 59 4e-09
gi|153792110 HEG homolog 1 [Homo sapiens] 59 7e-09
>gi|13449287 NG3 protein [Homo sapiens]
Length = 293
Score = 623 bits (1607), Expect = e-179
Identities = 293/293 (100%), Positives = 293/293 (100%)
Query: 1 MGSRAELCTLLGGFSFLLLLIPGEGAKGGSLRESQGVCSKQTLVVPLHYNESYSQPVYKP 60
MGSRAELCTLLGGFSFLLLLIPGEGAKGGSLRESQGVCSKQTLVVPLHYNESYSQPVYKP
Sbjct: 1 MGSRAELCTLLGGFSFLLLLIPGEGAKGGSLRESQGVCSKQTLVVPLHYNESYSQPVYKP 60
Query: 61 YLTLCAGRRICSTYRTMYRVMWREVRREVQQTHAVCCQGWKKRHPGALTCEAICAKPCLN 120
YLTLCAGRRICSTYRTMYRVMWREVRREVQQTHAVCCQGWKKRHPGALTCEAICAKPCLN
Sbjct: 61 YLTLCAGRRICSTYRTMYRVMWREVRREVQQTHAVCCQGWKKRHPGALTCEAICAKPCLN 120
Query: 121 GGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDG 180
GGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDG
Sbjct: 121 GGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDG 180
Query: 181 RTCMEGSPEPPTSASILSVAVREAEKDERALKQEIHELRGRLERLEQWAGQAGAWVRAVL 240
RTCMEGSPEPPTSASILSVAVREAEKDERALKQEIHELRGRLERLEQWAGQAGAWVRAVL
Sbjct: 181 RTCMEGSPEPPTSASILSVAVREAEKDERALKQEIHELRGRLERLEQWAGQAGAWVRAVL 240
Query: 241 PVPPEELQPEQVAELWGRGDRIESLSDQVLLLEERLGACSCEDNSLGLGVNHR 293
PVPPEELQPEQVAELWGRGDRIESLSDQVLLLEERLGACSCEDNSLGLGVNHR
Sbjct: 241 PVPPEELQPEQVAELWGRGDRIESLSDQVLLLEERLGACSCEDNSLGLGVNHR 293
>gi|41393583 EGF-like-domain, multiple 7 [Homo sapiens]
Length = 273
Score = 160 bits (405), Expect = 1e-39
Identities = 97/273 (35%), Positives = 139/273 (50%), Gaps = 17/273 (6%)
Query: 19 LLIPGEGAKGGSLRESQGVCSKQTLVVPLHYNESYSQPVYKPYLTLCAGRRICSTYRTMY 78
LL+ G + R + VC+ + P+ +ES+ Q VY+P+LT C G R CSTYRT+Y
Sbjct: 12 LLVLAVGGTEHAYRPGRRVCAVRAHGDPV--SESFVQRVYQPFLTTCDGHRACSTYRTIY 69
Query: 79 RVMWREVRREVQ-QTHAVCCQGWKKRH--PGALTCEAICAKPCLNGGVCVRPDQCECAPG 135
R +R + CC GWK+ PGA AIC PC NGG CV+P +C C G
Sbjct: 70 RTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGA-AICQPPCRNGGSCVQPGRCRCPAG 128
Query: 136 WGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCMEGSPEPPTSAS 195
W G C DVDEC C C NTAGS+ C C L DG C+ P + +
Sbjct: 129 WRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKGGPPRVAPN 188
Query: 196 ILSVAVREAEKDERALKQEIHELRGRLERLEQWAGQAGAWVRAVLPVPPEELQPEQ---V 252
V + A+K+E+ L+ R++ LE+ A + ++ E P+ +
Sbjct: 189 PTGV--------DSAMKEEVQRLQSRVDLLEEKLQLVLAPLHSLASQALEHGLPDPGSLL 240
Query: 253 AELWGRGDRIESLSDQVLLLEERLGACSCEDNS 285
+ + RI+SLS+Q+ LEE+LG+CSC+ +S
Sbjct: 241 VHSFQQLGRIDSLSEQISFLEEQLGSCSCKKDS 273
>gi|7705889 EGF-like-domain, multiple 7 [Homo sapiens]
Length = 273
Score = 160 bits (405), Expect = 1e-39
Identities = 97/273 (35%), Positives = 139/273 (50%), Gaps = 17/273 (6%)
Query: 19 LLIPGEGAKGGSLRESQGVCSKQTLVVPLHYNESYSQPVYKPYLTLCAGRRICSTYRTMY 78
LL+ G + R + VC+ + P+ +ES+ Q VY+P+LT C G R CSTYRT+Y
Sbjct: 12 LLVLAVGGTEHAYRPGRRVCAVRAHGDPV--SESFVQRVYQPFLTTCDGHRACSTYRTIY 69
Query: 79 RVMWREVRREVQ-QTHAVCCQGWKKRH--PGALTCEAICAKPCLNGGVCVRPDQCECAPG 135
R +R + CC GWK+ PGA AIC PC NGG CV+P +C C G
Sbjct: 70 RTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGA-AICQPPCRNGGSCVQPGRCRCPAG 128
Query: 136 WGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCMEGSPEPPTSAS 195
W G C DVDEC C C NTAGS+ C C L DG C+ P + +
Sbjct: 129 WRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKGGPPRVAPN 188
Query: 196 ILSVAVREAEKDERALKQEIHELRGRLERLEQWAGQAGAWVRAVLPVPPEELQPEQ---V 252
V + A+K+E+ L+ R++ LE+ A + ++ E P+ +
Sbjct: 189 PTGV--------DSAMKEEVQRLQSRVDLLEEKLQLVLAPLHSLASQALEHGLPDPGSLL 240
Query: 253 AELWGRGDRIESLSDQVLLLEERLGACSCEDNS 285
+ + RI+SLS+Q+ LEE+LG+CSC+ +S
Sbjct: 241 VHSFQQLGRIDSLSEQISFLEEQLGSCSCKKDS 273
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 92.4 bits (228), Expect = 4e-19
Identities = 57/160 (35%), Positives = 77/160 (48%), Gaps = 17/160 (10%)
Query: 37 VCSKQTLVV-----PLHYNESYSQPVYKP---YLTLCAGRRICSTYRTMYRVMWREVRRE 88
VC++Q L + P S++ PV+K + C G RT+Y + +R+V
Sbjct: 47 VCAEQELTLVGRRQPCVQALSHTVPVWKAGCGWQAWCVGHE----RRTVYYMGYRQVYTT 102
Query: 89 VQQTHAVCCQGWKKR--HPGALTCEAICAKPCLNGGVCV--RPDQCECAPGWGGKHCHVD 144
+T CC+GW ++ G L+ E A C +GG CV C C PG+ G C D
Sbjct: 103 EARTVLRCCRGWMQQPDEEGCLSAEC-SASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYD 161
Query: 145 VDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCM 184
VDECRT C H C NT GS+ C C L D RTC+
Sbjct: 162 VDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCL 201
Score = 60.5 bits (145), Expect = 2e-09
Identities = 38/111 (34%), Positives = 49/111 (44%), Gaps = 16/111 (14%)
Query: 85 VRREVQQTHAVCCQGWKKRHPGALTCEAICAKPCLN-GGVCVRPDQ-------CECAPGW 136
V+ + + C G++ + G + PC N G C+ Q CEC G+
Sbjct: 218 VQLTITRHRCQCRPGFQLQEDGR---HCVRRSPCANRNGSCMHRCQVVRGLARCECHVGY 274
Query: 137 ----GGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTC 183
GK C DVDEC + C+H C NT GSF C C LG DGR C
Sbjct: 275 QLAADGKACE-DVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQC 324
Score = 51.2 bits (121), Expect = 1e-06
Identities = 42/138 (30%), Positives = 52/138 (37%), Gaps = 30/138 (21%)
Query: 96 CCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLC 155
CCQ +PG C G + D C C DVDEC +S C
Sbjct: 381 CCQQVCTNNPGGYECGCYA-------GYRLSADGCGCE----------DVDECASSRGGC 423
Query: 156 SHHCFNTAGSFTCGCPHDLVLGVDGRTC-------MEGSPEPPTSASILSVAVREAE--- 205
HHC N AGSF C C L D R C ++ E P + +AV + E
Sbjct: 424 EHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQ 483
Query: 206 ---KDERALKQEIHELRG 220
D+ +E ELRG
Sbjct: 484 LFQDDDVGADEEEAELRG 501
Score = 44.3 bits (103), Expect = 1e-04
Identities = 37/113 (32%), Positives = 46/113 (40%), Gaps = 17/113 (15%)
Query: 84 EVRREVQQTHAVCCQGWKKRHPGALTCEAICAKPCLNGGVCVRP-DQCECAPGWGGKHCH 142
E+R E T C H +LTC+ C NGG C+ D C+C GW G C+
Sbjct: 498 ELRGEHTLTEKFVCLDDSFGHDCSLTCD-----DCRNGGTCLLGLDGCDCPEGWTGLICN 552
Query: 143 VDVDECRTSITLCSHHCF----NTAGSFT--CGCPHDLVLGVDGRTCMEGSPE 189
+ T CS C T S T C CP GV G C +G P+
Sbjct: 553 -ETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPP----GVSGTNCEDGCPK 600
Score = 43.1 bits (100), Expect = 3e-04
Identities = 34/112 (30%), Positives = 41/112 (36%), Gaps = 23/112 (20%)
Query: 110 CEAICAKPCLNGGVCVRPD-QCECAPGWGGKHCHVDVDECRTSITL---CSHH----CFN 161
CE C+ C NGG+C + C C GW G+HC + R CS H C
Sbjct: 1301 CEHTCS--CRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEP 1358
Query: 162 TAGSFTCG-------CPHDLVLGVDGR------TCMEGSPEPPTSASILSVA 200
G+ CG C H G G C G+P P S L A
Sbjct: 1359 ATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPA 1410
Score = 42.4 bits (98), Expect = 5e-04
Identities = 32/99 (32%), Positives = 39/99 (39%), Gaps = 12/99 (12%)
Query: 95 VCCQGWKKRHPGALTCEAICAKPCLNGGVC-VRPDQCECAPGWGGKHCHVDVDECRTSIT 153
VC GW +C+ C+ C N G C C CAPGW G C D
Sbjct: 816 VCPAGWY-----GPSCQTRCS--CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPD 868
Query: 154 LCSHHCFNTAGSFTCGCPHDLVL---GVDGRTCMEGSPE 189
CSH C +AG +C L L G G C + P+
Sbjct: 869 -CSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQ 906
Score = 41.2 bits (95), Expect = 0.001
Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 11/82 (13%)
Query: 112 AICAKPCLNGGVCVRPDQCECAPGW----GGKHCH----VDVDECRTSITLCSHHCFNTA 163
A CA CLN + C C G+ G+ C+ V+ C + CSH C +T+
Sbjct: 294 AQCAHGCLNTQGSFK---CVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTS 350
Query: 164 GSFTCGCPHDLVLGVDGRTCME 185
C CP L D RTC++
Sbjct: 351 AGPLCTCPRGYELDTDQRTCID 372
Score = 37.7 bits (86), Expect = 0.012
Identities = 26/77 (33%), Positives = 28/77 (36%), Gaps = 14/77 (18%)
Query: 104 HPGALTCEAICAKPCLNGGVCVRPD-QCECAPGWGGKHCHVDVDECRTSI--TLCSHHCF 160
H C CA C NG C QC CAPGW G C + C + C H C
Sbjct: 993 HTYGHNCSQACA--CFNGASCDPVHGQCHCAPGWMGPSC---LQACPAGLYGDNCRHSCL 1047
Query: 161 NTAG------SFTCGCP 171
G S C CP
Sbjct: 1048 CQNGGTCDPVSGHCACP 1064
Score = 31.2 bits (69), Expect = 1.1
Identities = 34/122 (27%), Positives = 39/122 (31%), Gaps = 25/122 (20%)
Query: 96 CCQGWK-----KRHPGAL---TCEAICAKPCLNGGVCVRPD-QCECAPGWGGKHCHVDV- 145
C GW + P L C C C NGG C C C GW G C +
Sbjct: 1020 CAPGWMGPSCLQACPAGLYGDNCRHSCL--CQNGGTCDPVSGHCACPEGWAGLACEKECL 1077
Query: 146 -----DECRTS-----ITLCSHH---CFNTAGSFTCGCPHDLVLGVDGRTCMEGSPEPPT 192
CR S LC H C AG C + G G C + PP
Sbjct: 1078 PRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPG 1137
Query: 193 SA 194
+A
Sbjct: 1138 AA 1139
Score = 30.8 bits (68), Expect = 1.5
Identities = 23/85 (27%), Positives = 29/85 (34%), Gaps = 16/85 (18%)
Query: 114 CAKPCLNGGVCVR--PDQCECAPGWGGKHCHVDVDE------CRTSITLCSH--HCFNTA 163
C+ C GG QC C PG G+ C D E C+ C H C
Sbjct: 740 CSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPET 799
Query: 164 GSFTCGCPHDLVLGVDGRTCMEGSP 188
G+ C + G G C + P
Sbjct: 800 GACLC------LPGFVGSRCQDVCP 818
Score = 30.4 bits (67), Expect = 1.9
Identities = 24/67 (35%), Positives = 27/67 (40%), Gaps = 15/67 (22%)
Query: 130 CECAPGWGGKHCHVDVDECRTSI--TLCSHHCFNTAG------SFTCGCPHDLVLGVDGR 181
C C PG G C++D CR C+ HC G S C C V G G
Sbjct: 1449 CLCPPGRSGATCNLD---CRRGQFGPSCTLHCDCGGGADCDPVSGQCHC----VDGYMGP 1501
Query: 182 TCMEGSP 188
TC EG P
Sbjct: 1502 TCREGGP 1508
Score = 28.1 bits (61), Expect = 9.6
Identities = 24/80 (30%), Positives = 29/80 (36%), Gaps = 20/80 (25%)
Query: 96 CCQGWKKRHPGALTCEAICAKPCLNGGVCVRP-DQCECAPGWGGKHCHVDVDECRTSITL 154
C +G+ +H C C C N G C R C C PG G+ CH+
Sbjct: 598 CPKGYYGKH-----CRKKCN--CANRGRCHRLYGACLCDPGLYGRFCHL----------T 640
Query: 155 CSHHCFNTAGSFTCGC--PH 172
C F S C C PH
Sbjct: 641 CPPWAFGPGCSEECQCVQPH 660
>gi|13124888 epidermal growth factor-like protein 6 precursor [Homo
sapiens]
Length = 553
Score = 79.3 bits (194), Expect = 4e-15
Identities = 40/97 (41%), Positives = 49/97 (50%), Gaps = 8/97 (8%)
Query: 92 THAVCCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTS 151
T CC GW++ G CEA C C G CV P++C C PG+ GK C DV+EC
Sbjct: 45 TKLACCYGWRRNSKGV--CEATCEPGC-KFGECVGPNKCRCFPGYTGKTCSQDVNECGMK 101
Query: 152 ITLCSHHCFNTAGSFTCGCPHDLVL-----GVDGRTC 183
C H C NT GS+ C C +L V+ RTC
Sbjct: 102 PRPCQHRCVNTHGSYKCFCLSGHMLMPDATCVNSRTC 138
Score = 45.4 bits (106), Expect = 6e-05
Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 20/138 (14%)
Query: 130 CECAPGW-----GGKHCHVDVDECRTSITLCSHH--CFNTAGSFTCGCPHDLVLGVDGRT 182
C+C G+ G++ +D++EC CSHH CFNT GSF C C +G
Sbjct: 200 CKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQG--YKGNGLR 257
Query: 183 CMEGSPEPPTSASILSVAVREAEKDERALKQEIHELRGRLERLEQWAGQAGAWVRAV-LP 241
C ++I +V+E + +K I +L +++ A P
Sbjct: 258 C----------SAIPENSVKEVLRAPGTIKDRIKKLLAHKNSMKKKAKIKNVTPEPTRTP 307
Query: 242 VPPEELQPEQVAELWGRG 259
P LQP E+ RG
Sbjct: 308 TPKVNLQPFNYEEIVSRG 325
Score = 34.3 bits (77), Expect = 0.13
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 10/69 (14%)
Query: 109 TCEAI-CAKPCLN---GGVCVRPDQ-CECAPGWGGKHCHVDVDECRTSITLCSHH--CFN 161
TC I C C + G C+ P AP G+ C +D+DEC + +C ++ C N
Sbjct: 137 TCAMINCQYSCEDTEEGPQCLCPSSGLRLAPN--GRDC-LDIDECASGKVICPYNRRCVN 193
Query: 162 TAGSFTCGC 170
T GS+ C C
Sbjct: 194 TFGSYYCKC 202
>gi|75709198 nephronectin [Homo sapiens]
Length = 565
Score = 77.8 bits (190), Expect = 1e-14
Identities = 33/85 (38%), Positives = 49/85 (57%), Gaps = 3/85 (3%)
Query: 96 CCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLC 155
CC GW ++ G C+ +C C +G C+ P++C+C PG+ GK C+ D++EC C
Sbjct: 44 CCWGWARQSWGQ--CQPVCQPRCKHGE-CIGPNKCKCHPGYAGKTCNQDLNECGLKPRPC 100
Query: 156 SHHCFNTAGSFTCGCPHDLVLGVDG 180
H C NT GS+ C C + +L DG
Sbjct: 101 KHRCMNTYGSYKCYCLNGYMLMPDG 125
Score = 37.7 bits (86), Expect = 0.012
Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 10/84 (11%)
Query: 96 CCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQ--CEC-APGW----GGKHCHVDVDEC 148
C G+ G+ + C+ G V Q C+C +PG G+ C VDVDEC
Sbjct: 115 CLNGYMLMPDGSCSSALTCSMANCQYGCDVVKGQIRCQCPSPGLQLAPDGRTC-VDVDEC 173
Query: 149 RTSITLCSH--HCFNTAGSFTCGC 170
T C C NT GS+ C C
Sbjct: 174 ATGRASCPRFRQCVNTFGSYICKC 197
Score = 37.7 bits (86), Expect = 0.012
Identities = 24/63 (38%), Positives = 31/63 (49%), Gaps = 11/63 (17%)
Query: 130 CECAPGW-----GGKH-CHVDVDECRTSITLCSH--HCFNTAGSFTCGCPHDLVLGVDGR 181
C+C G+ GGK+ CH D+DEC CS C+N GS+ C C DG
Sbjct: 195 CKCHKGFDLMYIGGKYQCH-DIDECSLGQYQCSSFARCYNIRGSYKCKCKEG--YQGDGL 251
Query: 182 TCM 184
TC+
Sbjct: 252 TCV 254
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 68.6 bits (166), Expect = 6e-12
Identities = 34/82 (41%), Positives = 47/82 (57%), Gaps = 9/82 (10%)
Query: 111 EAICAKPCLNGGVCVRPD---QCECAPGW----GGKHCHVDVDECRTSITLCSHHCFNTA 163
E CLNG +C+ D +C C PG+ G++C DVDEC+T + HC N+
Sbjct: 620 ECTTTNMCLNG-MCINEDGSFKCICKPGFVLAPNGRYC-TDVDECQTPGICMNGHCINSE 677
Query: 164 GSFTCGCPHDLVLGVDGRTCME 185
GSF C CP L +G+DGR C++
Sbjct: 678 GSFRCDCPPGLAVGMDGRVCVD 699
Score = 52.8 bits (125), Expect = 4e-07
Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 7/115 (6%)
Query: 96 CCQGWKKRHPG-ALTCEAICAKPCLNGGVCVRPDQ--CECAPGWGG---KHCHVDVDECR 149
C G+K+ G + + + PC NG P C+C G+ K +D+DEC
Sbjct: 521 CNMGYKQDANGDCIDVDECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECI 580
Query: 150 TSITLCSH-HCFNTAGSFTCGCPHDLVLGVDGRTCMEGSPEPPTSASILSVAVRE 203
+ LC + C NT GSF C C L DG+ C++ T+ + + + E
Sbjct: 581 QNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINE 635
Score = 52.8 bits (125), Expect = 4e-07
Identities = 25/61 (40%), Positives = 34/61 (55%), Gaps = 5/61 (8%)
Query: 129 QCECAPGW----GGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCM 184
+C C G+ G C +D+DEC S C++ C NT GS+ C CP VL DG+TC
Sbjct: 2473 RCFCKVGYTTDISGTSC-IDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCK 2531
Query: 185 E 185
+
Sbjct: 2532 D 2532
Score = 48.9 bits (115), Expect = 5e-06
Identities = 36/102 (35%), Positives = 44/102 (43%), Gaps = 16/102 (15%)
Query: 97 CQGWKKRHPGALTCEAICAKPCLNGGV------CVRPD---QCECAPGW----GGKHCHV 143
C +R P C I C+ GV CV D QC C G+ GK+C V
Sbjct: 560 CHAGFQRTPTKQAC--IDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNC-V 616
Query: 144 DVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCME 185
D DEC T+ + C N GSF C C VL +GR C +
Sbjct: 617 DHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTD 658
Score = 46.2 bits (108), Expect = 3e-05
Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 10/107 (9%)
Query: 88 EVQQTHAVCCQGWKKRHPGAL---TCEAICAKPCLNGGVCVRPD---QCECAPGWGGK-- 139
E+ +C +G++ G T E + + G C + +C C PG+ K
Sbjct: 1993 EIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSE 2052
Query: 140 HCHVDVDECRTSITLCSH-HCFNTAGSFTCGCPHDLVLGVDGRTCME 185
+C +D++EC +C C NT G F C CP VL +GR C +
Sbjct: 2053 NC-IDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFD 2098
Score = 46.2 bits (108), Expect = 3e-05
Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 7/97 (7%)
Query: 96 CCQGWKKRHPGAL---TCEAICAKPCLNGGVC--VRPDQCECAPGW--GGKHCHVDVDEC 148
C G+ + G T E PC NG + +C C G+ G D++EC
Sbjct: 2198 CPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINEC 2257
Query: 149 RTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCME 185
+ LC+ C NT GS+ C CP L D + C +
Sbjct: 2258 AQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKD 2294
Score = 46.2 bits (108), Expect = 3e-05
Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 11/99 (11%)
Query: 96 CCQGWKKRHPGALTCEAICAKPCLNG--GVCVRPD---QCECAPGWG----GKHCHVDVD 146
C G+ + H + ++P L G G+C CEC G+ G +C DVD
Sbjct: 2558 CPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCE-DVD 2616
Query: 147 ECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCME 185
EC + C H C N G + CGCP + C++
Sbjct: 2617 ECDGNHR-CQHGCQNILGGYRCGCPQGYIQHYQWNQCVD 2654
Score = 45.8 bits (107), Expect = 4e-05
Identities = 22/60 (36%), Positives = 33/60 (55%), Gaps = 6/60 (10%)
Query: 129 QCECAPGW----GGKHCHVDVDECRTSITLCSHH-CFNTAGSFTCGCPHDLVLGVDGRTC 183
+C C G+ G++C +D+DEC + LC + C NT GS++C CP V + TC
Sbjct: 792 RCNCNSGYEPDASGRNC-IDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETC 850
Score = 45.8 bits (107), Expect = 4e-05
Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 3/60 (5%)
Query: 129 QCECAPGWGG---KHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCME 185
QC C PG+ + D+DEC C C N+ GS+ C C L DGR+C +
Sbjct: 1224 QCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCAD 1283
Score = 45.8 bits (107), Expect = 4e-05
Identities = 26/63 (41%), Positives = 31/63 (49%), Gaps = 10/63 (15%)
Query: 116 KPCLNGGVCVRPD---QCECAPGW----GGKHCHVDVDECRTSITLCSHHCFNTAGSFTC 168
KPC +C + QC C G+ GK C D+DEC+T C C NT G FTC
Sbjct: 2500 KPC--NYICKNTEGSYQCSCPRGYVLQEDGKTCK-DLDECQTKQHNCQFLCVNTLGGFTC 2556
Query: 169 GCP 171
CP
Sbjct: 2557 KCP 2559
Score = 45.1 bits (105), Expect = 8e-05
Identities = 27/80 (33%), Positives = 30/80 (37%), Gaps = 9/80 (11%)
Query: 93 HAVCCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSI 152
H+ CC GWK G IC C G C RP+ C C+ G C SI
Sbjct: 94 HSYCCPGWKTLPGGNQCIVPICRNSC-GDGFCSRPNMCTCSSGQISSTCG------SKSI 146
Query: 153 TLCSHHCFN--TAGSFTCGC 170
CS C N T C C
Sbjct: 147 QQCSVRCMNGGTCADDHCQC 166
Score = 44.7 bits (104), Expect = 1e-04
Identities = 48/169 (28%), Positives = 64/169 (37%), Gaps = 40/169 (23%)
Query: 51 ESYSQPVYKPYLTLC------AGRRICSTYRTMYRVMWREVRREVQQTHAVCCQGWKKRH 104
E +P K Y TLC A R T R Y+ + E + +C G +
Sbjct: 1038 EECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDI-----NECKAFPGMCTYGKCRNT 1092
Query: 105 PGALTC-----------EAICA-------KPCLNG-GVCVRPD---QCECAPGWGG---- 138
G+ C E C P L G G+CV +CEC G+
Sbjct: 1093 IGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMM 1152
Query: 139 -KHCHVDVDECRTSITLC-SHHCFNTAGSFTCGCPHDLVLGVDGRTCME 185
K+C +D+DEC + LC C NT GSF C CP L C++
Sbjct: 1153 MKNC-MDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVD 1200
Score = 44.3 bits (103), Expect = 1e-04
Identities = 37/130 (28%), Positives = 47/130 (36%), Gaps = 40/130 (30%)
Query: 92 THAVCCQ--GWKKRHPGALTCEAICAKP--CLNG-------GVCVRPDQCECAPGW---- 136
T +CC G HP CE A+P C G G C D+C+ PG
Sbjct: 235 TKTLCCATIGRAWGHP----CEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGG 290
Query: 137 ------GGKHCHV--------------DVDECRTSITLC-SHHCFNTAGSFTCGCPHDLV 175
G C D+DEC +C + C NT GS+ C CP V
Sbjct: 291 NCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYV 350
Query: 176 LGVDGRTCME 185
DG C++
Sbjct: 351 TSTDGSRCID 360
Score = 43.5 bits (101), Expect = 2e-04
Identities = 27/110 (24%), Positives = 44/110 (40%), Gaps = 19/110 (17%)
Query: 44 VVPLHYNESYSQPVYKPYLTLCAGRRICSTYRTMYRVMWREVRREVQQTHAVCCQGW--- 100
+VP+ N +P + C+ +I ST + + +QQ C G
Sbjct: 111 IVPICRNSCGDGFCSRPNMCTCSSGQISSTCGS----------KSIQQCSVRCMNGGTCA 160
Query: 101 ------KKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVD 144
+K + G + +C C NGG C+ P++C C G+ G C D
Sbjct: 161 DDHCQCQKGYIGTYCGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERD 210
Score = 43.1 bits (100), Expect = 3e-04
Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 9/73 (12%)
Query: 121 GGVCVRPD---QCECAPGW----GGKHCHVDVDECRTSITLCSHH-CFNTAGSFTCGCPH 172
GG C+ QCEC G+ + C D+DEC +C C+NT G++TC CP
Sbjct: 1663 GGNCINTFGSFQCECPQGYYLSEDTRICE-DIDECFAHPGVCGPGTCYNTLGNYTCICPP 1721
Query: 173 DLVLGVDGRTCME 185
+ + G CM+
Sbjct: 1722 EYMQVNGGHNCMD 1734
Score = 43.1 bits (100), Expect = 3e-04
Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 8/99 (8%)
Query: 95 VCCQGWKKRHPGALTCEAI-CAKPCLNGGVC---VRPDQCECAPGWGGKHCH--VDVDEC 148
+C G+K + + C + G C V C C PG+ H + +D+DEC
Sbjct: 1918 ICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDEC 1977
Query: 149 RTSI-TLCSH-HCFNTAGSFTCGCPHDLVLGVDGRTCME 185
+ +C + CFN GSF C C L DG+ C++
Sbjct: 1978 SSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCID 2016
Score = 43.1 bits (100), Expect = 3e-04
Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 5/47 (10%)
Query: 129 QCECAPGWG----GKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCP 171
+C C G+ CH DV+EC +S C++ C NT G + CGCP
Sbjct: 2677 KCACPSGFSFDQFSSACH-DVNECSSSKNPCNYGCSNTEGGYLCGCP 2722
Score = 42.4 bits (98), Expect = 5e-04
Identities = 27/105 (25%), Positives = 44/105 (41%), Gaps = 12/105 (11%)
Query: 92 THAVCCQGWKKRHPGALTCEAICAKPCLNGGV---CVRPD---QCECAPGWG----GKHC 141
T+ C + P C I +NGG C + +C C+ G+ G+ C
Sbjct: 1222 TYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSC 1281
Query: 142 HVDVDECRTSITLCSH-HCFNTAGSFTCGCPHDLVLGVDGRTCME 185
D+DEC + +C C N G + C C + +D +TC++
Sbjct: 1282 -ADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCID 1325
Score = 42.0 bits (97), Expect = 6e-04
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 129 QCECAPGWGGKHCHV-DVDECRTSITLCSH-HCFNTAGSFTCGCPHDLVLGVDGRTCME 185
+C C+ G+ G DVDEC +I LC + C N G++ C C D R+C +
Sbjct: 1433 RCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQD 1491
Score = 41.6 bits (96), Expect = 8e-04
Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 129 QCECAPGWGGKHCH-VDVDECRTSITLCSHH--CFNTAGSFTCGCPHDLVLGVDGRTCME 185
+C C GW G +D+DEC CS + C NT GS+ C C DG TC +
Sbjct: 1392 KCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFT--GDGFTCSD 1449
Score = 41.6 bits (96), Expect = 8e-04
Identities = 33/111 (29%), Positives = 48/111 (43%), Gaps = 27/111 (24%)
Query: 92 THAVCC----QGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGW--GGKHCHVDV 145
T + CC +GW + CE +C P G C PG+ G+ D+
Sbjct: 2406 TKSECCCDGGRGWGHQ------CE-LCPLP----GTAQYKKICPHGPGYTTDGR----DI 2450
Query: 146 DECRTSITLCSH-HCFNTAGSFTCGCPHDLVLGVDGRTCME-----GSPEP 190
DEC+ LC++ C NT GSF C C + G +C++ SP+P
Sbjct: 2451 DECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKP 2501
Score = 41.2 bits (95), Expect = 0.001
Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 130 CECAPGWG----GKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCME 185
C C G+ G +C D+DEC I + C NT G + C CP D L G C++
Sbjct: 1515 CICDDGYELDRTGGNC-TDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVD 1573
Score = 40.8 bits (94), Expect = 0.001
Identities = 19/41 (46%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 144 DVDECRTSITLCSH-HCFNTAGSFTCGCPHDLVLGVDGRTC 183
D+DEC+ LC +C NT GSF C CP L D R C
Sbjct: 1650 DIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRIC 1690
Score = 40.4 bits (93), Expect = 0.002
Identities = 18/43 (41%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 144 DVDECRTSITLCSH-HCFNTAGSFTCGCPHDLVLGVDGRTCME 185
DV+EC +C + C N+ GSF C CP L L GR C++
Sbjct: 955 DVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLD 997
Score = 38.9 bits (89), Expect = 0.005
Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 144 DVDECRTSITLCSH-HCFNTAGSFTCGCPHDLVLGVDGRTCME 185
DV+EC S +CS+ C NT GSF C CP L G C++
Sbjct: 2171 DVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVD 2213
Score = 38.9 bits (89), Expect = 0.005
Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 6/61 (9%)
Query: 130 CECAPGWG----GKHCHVDVDECRTSITLCSH-HCFNTAGSFTCGCPHDLVLGVDGRTCM 184
C C PG G+ C VD +ECRT +C + C N GS+ C C G C+
Sbjct: 2321 CICPPGMARRPDGEGC-VDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECL 2379
Query: 185 E 185
+
Sbjct: 2380 D 2380
Score = 38.5 bits (88), Expect = 0.007
Identities = 26/81 (32%), Positives = 35/81 (43%), Gaps = 14/81 (17%)
Query: 118 CLNGGVCVRPD---QCECAPGWGGKHCHV---DVDECRTSITLCSHH--CFNTAGSFTCG 169
C NG VC+ +CEC G+ + D+DEC LC + C N+ GS+ C
Sbjct: 1819 CANG-VCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCE 1877
Query: 170 CPHDLVLG-----VDGRTCME 185
C L VD C+E
Sbjct: 1878 CAAGFKLSPNGACVDRNECLE 1898
Score = 37.0 bits (84), Expect = 0.021
Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 10/91 (10%)
Query: 105 PGALT-CEAICAKPCLNGGVCVRPDQCE--------CAPGWGGKHCHVDVDECRTSITLC 155
PGA+T E CA P G +P + C+ G G D++EC +C
Sbjct: 720 PGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDIC 779
Query: 156 SHH-CFNTAGSFTCGCPHDLVLGVDGRTCME 185
++ C N GS+ C C GR C++
Sbjct: 780 ANGICENLRGSYRCNCNSGYEPDASGRNCID 810
Score = 36.6 bits (83), Expect = 0.027
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 11/80 (13%)
Query: 113 ICAKPCLNGGVCVRPDQCECAPGWG----GKHCHVDVDECRTSITLCSHH---CFNTAGS 165
+CA C+N +C C G+ K C D+DEC + C C N G+
Sbjct: 2263 LCAFRCMN---TFGSYECTCPIGYALREDQKMCK-DLDECAEGLHDCESRGMMCKNLIGT 2318
Query: 166 FTCGCPHDLVLGVDGRTCME 185
F C CP + DG C++
Sbjct: 2319 FMCICPPGMARRPDGEGCVD 2338
Score = 36.2 bits (82), Expect = 0.035
Identities = 27/86 (31%), Positives = 35/86 (40%), Gaps = 13/86 (15%)
Query: 92 THAVCCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGWG-----GKHCHVDVD 146
T +CC + CE PC G C PG+ GK VD+D
Sbjct: 1758 TKRMCCCTYNVGKAWNKPCE-----PCPTPGTADFKTICGNIPGFTFDIHTGKA--VDID 1810
Query: 147 ECRTSITLCSHH-CFNTAGSFTCGCP 171
EC+ +C++ C N GSF C CP
Sbjct: 1811 ECKEIPGICANGVCINQIGSFRCECP 1836
Score = 35.8 bits (81), Expect = 0.046
Identities = 29/91 (31%), Positives = 38/91 (41%), Gaps = 15/91 (16%)
Query: 108 LTCEAICAKPCLNG-GVCVRPD---------QCECAPGW--GGKHCHVDVDECRTSITLC 155
L CE I C NG +C R +CECA G+ VD +EC +C
Sbjct: 1846 LVCEDI--DECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVC 1903
Query: 156 SHH-CFNTAGSFTCGCPHDLVLGVDGRTCME 185
SH C + GS+ C C + D CM+
Sbjct: 1904 SHGLCVDLQGSYQCICHNGFKASQDQTMCMD 1934
Score = 34.7 bits (78), Expect = 0.10
Identities = 22/66 (33%), Positives = 26/66 (39%), Gaps = 15/66 (22%)
Query: 119 LNGGVCVRPDQCECAPGWGGKHCHV------------DVDECRTSITLCSHH--CFNTAG 164
LN +C+ +CE G HC + DVDEC C H C N G
Sbjct: 1331 LNSNICMF-GECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPG 1389
Query: 165 SFTCGC 170
SF C C
Sbjct: 1390 SFKCSC 1395
Score = 34.3 bits (77), Expect = 0.13
Identities = 37/136 (27%), Positives = 48/136 (35%), Gaps = 41/136 (30%)
Query: 50 NESYSQPVYKPYLTLCAGRRICSTYRTMYRVMWREVRREVQQTHAVCCQGWKKRHPGALT 109
NE SQP +LC + IC + C +G+ G L
Sbjct: 2573 NECGSQP------SLCGAKGICQNTPGSFS--------------CECQRGFSLDATG-LN 2611
Query: 110 CEAI--------CAKPCLN--GGVCVRPDQCECAPGW----GGKHCHVDVDECRTSITLC 155
CE + C C N GG +C C G+ C VD +EC
Sbjct: 2612 CEDVDECDGNHRCQHGCQNILGGY-----RCGCPQGYIQHYQWNQC-VDENECSNPNACG 2665
Query: 156 SHHCFNTAGSFTCGCP 171
S C+NT GS+ C CP
Sbjct: 2666 SASCYNTLGSYKCACP 2681
Score = 32.7 bits (73), Expect = 0.39
Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 15/94 (15%)
Query: 120 NGGVCVRPD---QCECAPGWGG----KHCHVDVDECRTSITLCSH-HCFNTAGSFTCGCP 171
+GG C +C C G+ K C +DV+EC + +C C NT GSF C C
Sbjct: 1295 DGGQCTNIPGEYRCLCYDGFMASMDMKTC-IDVNECDLNSNICMFGECENTKGSFICHCQ 1353
Query: 172 --HDLVLGVDGRT----CMEGSPEPPTSASILSV 199
+ + G G T C G+ AS L++
Sbjct: 1354 LGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNI 1387
Score = 30.4 bits (67), Expect = 1.9
Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 6/60 (10%)
Query: 130 CECAPGW----GGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCME 185
C C PG+ + C D++EC ++ + + C N GSF C C L G C++
Sbjct: 835 CTCPPGYVFRTETETCE-DINECESNPCV-NGACRNNLGSFNCECSPGSKLSSTGLICID 892
Score = 29.6 bits (65), Expect = 3.3
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 7/74 (9%)
Query: 118 CLNGGVCVRPD--QCECAPGW----GGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCP 171
C NG P +CEC G+ + C D+DEC C N G F C C
Sbjct: 1460 CENGQCLNVPGAYRCECEMGFTPASDSRSCQ-DIDECSFQNICVFGTCNNLPGMFHCICD 1518
Query: 172 HDLVLGVDGRTCME 185
L G C +
Sbjct: 1519 DGYELDRTGGNCTD 1532
>gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens]
Length = 810
Score = 67.8 bits (164), Expect = 1e-11
Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 6/82 (7%)
Query: 110 CEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLCSHH--CFNTAGSFT 167
C A C + C GG CV P++C C G+ G HC D+DEC I C +H C N G +
Sbjct: 515 CRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYH 574
Query: 168 CGC----PHDLVLGVDGRTCME 185
C C D + G +C++
Sbjct: 575 CECRSGFHDDGTYSLSGESCID 596
>gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]
Length = 763
Score = 67.4 bits (163), Expect = 1e-11
Identities = 29/64 (45%), Positives = 34/64 (53%), Gaps = 2/64 (3%)
Query: 110 CEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDEC--RTSITLCSHHCFNTAGSFT 167
C A C + C GG CV P++C C G+ G HC D+DEC RT C N AG F
Sbjct: 515 CRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECALRTHTCWNDSACINLAGGFD 574
Query: 168 CGCP 171
C CP
Sbjct: 575 CLCP 578
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 64.7 bits (156), Expect = 9e-11
Identities = 34/82 (41%), Positives = 46/82 (56%), Gaps = 9/82 (10%)
Query: 111 EAICAKPCLNGGVCVRPD---QCECAPGW----GGKHCHVDVDECRTSITLCSHHCFNTA 163
E + C+NG VC+ D C C PG+ GG +C +D+DEC+T + HC NT
Sbjct: 534 ECATSTMCVNG-VCLNEDGSFSCLCKPGFLLAPGGHYC-MDIDECQTPGICVNGHCTNTE 591
Query: 164 GSFTCGCPHDLVLGVDGRTCME 185
GSF C C L +G DGR C++
Sbjct: 592 GSFRCQCLGGLAVGTDGRVCVD 613
Score = 52.8 bits (125), Expect = 4e-07
Identities = 28/72 (38%), Positives = 39/72 (54%), Gaps = 7/72 (9%)
Query: 121 GGVCVRPD---QCECAPGWG-GKHCHV--DVDECRTSITLCSHH-CFNTAGSFTCGCPHD 173
GG CV QCEC PG+ +H + D+DEC T +C C+NT G++TC CP +
Sbjct: 1576 GGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAE 1635
Query: 174 LVLGVDGRTCME 185
+ G CM+
Sbjct: 1636 YLQVNGGNNCMD 1647
Score = 51.6 bits (122), Expect = 8e-07
Identities = 44/160 (27%), Positives = 57/160 (35%), Gaps = 34/160 (21%)
Query: 60 PYLTLCAGRRICSTYRTMYRVMWREVRREVQQ-THAVCC----QGWKKRH-----PGALT 109
P LT C R + + + M R + + T A CC +GW R PG
Sbjct: 2287 PTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSA 2346
Query: 110 CEAICAKPCLNGGVCVRPDQC----------ECAPGWGGKHCH--------------VDV 145
+C D+C EC G CH +D+
Sbjct: 2347 YRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 2406
Query: 146 DECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCME 185
DEC C+ C NT GSF C CP +L DGRTC +
Sbjct: 2407 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKD 2446
Score = 50.8 bits (120), Expect = 1e-06
Identities = 36/101 (35%), Positives = 46/101 (45%), Gaps = 18/101 (17%)
Query: 98 QGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCE----CAPGWG---GKHCHVDVDECRT 150
QG R T A PC ++CE CA G+ G C DV+EC +
Sbjct: 826 QGASLRSECCATLGAAWGSPC---------ERCEIDPACARGFARMTGVTCD-DVNECES 875
Query: 151 SITLCSH-HCFNTAGSFTCGCPHDLVLGVDGRTCMEGSPEP 190
+C + C NTAGSF C CP L+L GR C++ EP
Sbjct: 876 FPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEP 916
Score = 50.8 bits (120), Expect = 1e-06
Identities = 49/188 (26%), Positives = 72/188 (38%), Gaps = 14/188 (7%)
Query: 8 CTLLGGFSFLLLLIPGEGAKGGSLRESQGVCSKQTLVVPLHYNESYSQPVYKPYLTLCAG 67
C GF++ +L+ E RES + + +P Y ++ C G
Sbjct: 1746 CECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVG 1805
Query: 68 RRICSTYRTMYRVMWREVRREVQQTHAVCCQGWKKRHPGALTCEAI--CAKPCLNGGVC- 124
R C R + V + + ++ C + C I C + G C
Sbjct: 1806 RNEC---REIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCK 1862
Query: 125 --VRPDQCECAPGWGGKH---CHVDVDECRTSI-TLCSH-HCFNTAGSFTCGCPHDLVLG 177
+ C C PG+ H C VD DEC T + +C HC NTAGSF C C L
Sbjct: 1863 NIIGSYNCLCFPGFVVTHNGDC-VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELT 1921
Query: 178 VDGRTCME 185
DG+ C++
Sbjct: 1922 ADGKNCVD 1929
Score = 50.1 bits (118), Expect = 2e-06
Identities = 36/126 (28%), Positives = 45/126 (35%), Gaps = 23/126 (18%)
Query: 83 REVRREVQQTHAVCCQGWKKRHPGALTCEAICAKPCLNGGV-CVRPDQCE---------C 132
RE E + VC G G+ CE G+ CV D+C C
Sbjct: 2082 REDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTC 2141
Query: 133 APGWGGKHCHV-------------DVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVD 179
GG C D+DEC + LC+ C NT GS+ C CP L D
Sbjct: 2142 TNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLRED 2201
Query: 180 GRTCME 185
G C +
Sbjct: 2202 GAMCRD 2207
Score = 49.3 bits (116), Expect = 4e-06
Identities = 31/95 (32%), Positives = 43/95 (45%), Gaps = 6/95 (6%)
Query: 115 AKPCLNGGVCVRPD--QCECAPGWGG---KHCHVDVDECRTSITLCS-HHCFNTAGSFTC 168
+ PC +G P C C PG+ + VDVDEC S LC C NT GSF C
Sbjct: 455 SSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQC 514
Query: 169 GCPHDLVLGVDGRTCMEGSPEPPTSASILSVAVRE 203
C L DG+ C++ + ++ + V + E
Sbjct: 515 VCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNE 549
Score = 48.5 bits (114), Expect = 7e-06
Identities = 36/119 (30%), Positives = 46/119 (38%), Gaps = 29/119 (24%)
Query: 95 VCCQGWKKRHPGALTCEAI------------------CAKPCL--NGGVCVRPD---QCE 131
+C QG PG+ CE CA+ L GG C D +C+
Sbjct: 1038 LCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQ 1097
Query: 132 CAPGWG----GKHCHVDVDECRTSITLCSH-HCFNTAGSFTCGCPHDLVLGVDGRTCME 185
C PG G C D+DEC S LC H C N G+F C C D + C++
Sbjct: 1098 CPPGHELTAKGTACE-DIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVD 1155
Score = 48.5 bits (114), Expect = 7e-06
Identities = 23/60 (38%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
Query: 129 QCECAPGWGG---KHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCME 185
QC C G+ + VD++ECR C HC NT GS+ C C L DGR C +
Sbjct: 1137 QCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACAD 1196
Score = 48.1 bits (113), Expect = 9e-06
Identities = 41/157 (26%), Positives = 53/157 (33%), Gaps = 38/157 (24%)
Query: 65 CAGRRICSTYRTMYRVMWR----------EVRREVQQTHAVCCQGWKKRHPGALTCEA-- 112
C+ R C YR R E R E + +C G PG CE
Sbjct: 1332 CSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEM 1391
Query: 113 ---------IC--AKPCLNGGVCVRPDQCECAPGW-------------GGKHCHVDVDEC 148
C C G +C CE PG GG +C D++EC
Sbjct: 1392 GFDPTEDHRACQDVDECAQGNLCAF-GSCENLPGMFRCICNGGYELDRGGGNC-TDINEC 1449
Query: 149 RTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCME 185
+ + C NT GS+ C CP D L G C++
Sbjct: 1450 ADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVD 1486
Score = 47.4 bits (111), Expect = 2e-05
Identities = 33/106 (31%), Positives = 46/106 (43%), Gaps = 18/106 (16%)
Query: 93 HAVCCQGWKKRHPGALTCEAICAKPCLN-GGVCVRPDQCE---------CAPGWG--GKH 140
H +C G++ G + CL+ G C+ P C+ C PG+ H
Sbjct: 1911 HCLCQDGFELTADGK---NCVDTNECLSLAGTCL-PGTCQNLEGSFRCICPPGFQVQSDH 1966
Query: 141 CHVDVDECRTSITLCSHH-CFNTAGSFTCGCPHDLVLGVDGRTCME 185
C +D+DEC LC C N+ GSF C CP VL +G C +
Sbjct: 1967 C-IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFD 2011
Score = 47.0 bits (110), Expect = 2e-05
Identities = 34/96 (35%), Positives = 41/96 (42%), Gaps = 10/96 (10%)
Query: 109 TCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTC 168
TC + + L G CV P + GG C +VDEC CS+ C NT G F C
Sbjct: 2578 TCGSASCRNTLGGFRCVCPSGFDFDQALGG--CQ-EVDECAGRRGPCSYSCANTPGGFLC 2634
Query: 169 GCPHDLVLGVDGRTCMEG---SPEP---PTSASILS 198
GCP G C+ G SP P P +LS
Sbjct: 2635 GCPQGYFRAGQGH-CVSGLGFSPGPQDTPDKEELLS 2669
Score = 46.2 bits (108), Expect = 3e-05
Identities = 36/110 (32%), Positives = 44/110 (40%), Gaps = 13/110 (11%)
Query: 86 RREVQQTHAVCCQGWK--KRHPGALTCEAICAKPCLNG-GVCVRPD---QCECAPGWGG- 138
R V H C G+ + + P L G G CV +CEC PG+
Sbjct: 1003 RNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESG 1062
Query: 139 ----KHCHVDVDECRTSITLC-SHHCFNTAGSFTCGCPHDLVLGVDGRTC 183
K+C +DVDEC LC C NT GS+ C CP L G C
Sbjct: 1063 FMLMKNC-MDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Score = 45.1 bits (105), Expect = 8e-05
Identities = 34/104 (32%), Positives = 46/104 (44%), Gaps = 13/104 (12%)
Query: 93 HAVCCQGWKKRHPGALTC----EAICAKPCLNGGVCVRPD---QCECAPGW----GGKHC 141
H C G++ P C E I + + G CV + QC C G+ GK+C
Sbjct: 471 HCRCYPGFQAT-PTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 529
Query: 142 HVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCME 185
VD +EC TS + C N GSF+C C +L G CM+
Sbjct: 530 -VDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMD 572
Score = 44.7 bits (104), Expect = 1e-04
Identities = 53/201 (26%), Positives = 72/201 (35%), Gaps = 26/201 (12%)
Query: 2 GSRAELCTLLGGFSFLLLLIPGEG--AKGGSLRESQ---GVCSKQTLVVPLHYNESYSQP 56
G R ELC L G ++ L G G A+G + E + +C+ + L + Q
Sbjct: 2333 GPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQA 2392
Query: 57 VYKP--YLTLCAGRRICSTYRTMYRVMWREVRREVQQTHAVCCQGWKKRHPGALTCEAI- 113
Y P T C CS + + + + C +G+ G TC+ +
Sbjct: 2393 GYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCS---CPRGYLLEEDGR-TCKDLD 2448
Query: 114 --------CAKPCLNGGVCVRPDQCECAPGWGGKH-CHVDVDECRTSITLCSHH--CFNT 162
C C+N V C C PG+ H D DEC C H C NT
Sbjct: 2449 ECTSRQHNCQFLCVN---TVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNT 2505
Query: 163 AGSFTCGCPHDLVLGVDGRTC 183
GSF C C L G C
Sbjct: 2506 PGSFRCECHQGFTLVSSGHGC 2526
Score = 43.1 bits (100), Expect = 3e-04
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 11/74 (14%)
Query: 101 KKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCF 160
+K + G + + IC + C NGG C+ P++C C G+ G C D RT CF
Sbjct: 138 QKGYTGTVCGQPICDRGCHNGGRCIGPNRCACVYGFMGPQCERDY---RTG------PCF 188
Query: 161 NTAGSFTCGCPHDL 174
G GC H L
Sbjct: 189 GQVGPE--GCQHQL 200
Score = 42.0 bits (97), Expect = 6e-04
Identities = 31/94 (32%), Positives = 38/94 (40%), Gaps = 15/94 (15%)
Query: 93 HAVCCQGWKKRHPGALTCEA-ICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTS 151
HA CC GW+ PG C IC + C G C +P+ C CA G C V +
Sbjct: 65 HAYCCPGWRT-FPGRSQCVVPICRRAC-GEGFCSQPNLCTCADGTLAPSCGV------SR 116
Query: 152 ITLCSHHCFN--TAGSFTCGCPHDLVLGVDGRTC 183
+ CS C N T +C C G G C
Sbjct: 117 GSGCSVSCMNGGTCRGASCLCQK----GYTGTVC 146
Score = 41.2 bits (95), Expect = 0.001
Identities = 28/96 (29%), Positives = 38/96 (39%), Gaps = 24/96 (25%)
Query: 95 VCCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPG---WGGKHCHVDVDECRTS 151
+C GW + PG+ +C C PG W DVDEC +S
Sbjct: 734 LCDNGWCQNSPGSYSCS--------------------CPPGFHFWQDTEICKDVDECLSS 773
Query: 152 ITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCMEGS 187
+ S C N AGS+TC C L G C++ +
Sbjct: 774 PCV-SGVCRNLAGSYTCKCGPGSRLDPSGTFCLDST 808
Score = 41.2 bits (95), Expect = 0.001
Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 17/98 (17%)
Query: 105 PGALTCEAICAKPCLNGGV----CVRPDQCE----CAPGWG--------GKHCHVDVDEC 148
PG + C GV C P+ E C G G G+ + DV+EC
Sbjct: 931 PGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNEC 990
Query: 149 RTSITLCSHH-CFNTAGSFTCGCPHDLVLGVDGRTCME 185
+ LC+H C NT GSF C C L R C +
Sbjct: 991 KVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTD 1028
Score = 40.8 bits (94), Expect = 0.001
Identities = 29/84 (34%), Positives = 34/84 (40%), Gaps = 18/84 (21%)
Query: 88 EVQQTHAVCCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDE 147
E ++ VC QG PG C +C G PD C VDVDE
Sbjct: 1199 ECEENPRVCDQGHCTNMPGGHRC--LCYD-----GFMATPDMRTC----------VDVDE 1241
Query: 148 CRTSITLCSH-HCFNTAGSFTCGC 170
C + +C H C NT GSF C C
Sbjct: 1242 CDLNPHICLHGDCENTKGSFVCHC 1265
Score = 40.4 bits (93), Expect = 0.002
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 12/77 (15%)
Query: 120 NGGV---CVRPD---QCECAPGWG----GKHCHVDVDECRTSITLCSH-HCFNTAGSFTC 168
NGG C+ + +C C G+ G+ C DVDEC + +C HC N G C
Sbjct: 1163 NGGCDVHCINTEGSYRCSCGQGYSLMPDGRAC-ADVDECEENPRVCDQGHCTNMPGGHRC 1221
Query: 169 GCPHDLVLGVDGRTCME 185
C + D RTC++
Sbjct: 1222 LCYDGFMATPDMRTCVD 1238
Score = 40.4 bits (93), Expect = 0.002
Identities = 20/45 (44%), Positives = 23/45 (51%), Gaps = 5/45 (11%)
Query: 130 CECAPGW--GGKHCHVDVDECRTSITLCSHH--CFNTAGSFTCGC 170
C C PGW G CH D+DEC + CS C N GS+ C C
Sbjct: 1306 CRCLPGWVGDGFECH-DLDECVSQEHRCSPRGDCLNVPGSYRCTC 1349
Score = 39.3 bits (90), Expect = 0.004
Identities = 32/112 (28%), Positives = 42/112 (37%), Gaps = 14/112 (12%)
Query: 96 CCQGWKKRHPGALTCEAICAKP--CLNGGVCVRPD---QCECAPGW----GGKHCHVDVD 146
C G+ + H + A+P C G C +CEC G+ G C DV+
Sbjct: 2472 CPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCE-DVN 2530
Query: 147 ECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCM---EGSPEPPTSAS 195
EC C H C N G + C CP C+ E + PPT S
Sbjct: 2531 EC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGS 2581
Score = 38.9 bits (89), Expect = 0.005
Identities = 26/76 (34%), Positives = 32/76 (42%), Gaps = 8/76 (10%)
Query: 96 CCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLC 155
C G + H + C K + CV P PG G+ C D +EC LC
Sbjct: 2211 CADGQQDCHARGMEC-----KNLIGTFACVCPPGMRPLPG-SGEGC-TDDNECHAQPDLC 2263
Query: 156 SH-HCFNTAGSFTCGC 170
+ C NTAGSF C C
Sbjct: 2264 VNGRCVNTAGSFRCDC 2279
Score = 37.0 bits (84), Expect = 0.021
Identities = 27/91 (29%), Positives = 38/91 (41%), Gaps = 10/91 (10%)
Query: 105 PGALT-CEAICAKPCLNGG----VCVRPDQCE----CAPGWGGKHCHVDVDECRTSITLC 155
PG +T E CA P G +C D E C+ G G D++EC +C
Sbjct: 634 PGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGRDINECALDPEVC 693
Query: 156 SHH-CFNTAGSFTCGCPHDLVLGVDGRTCME 185
++ C N GS+ C C G G+ C +
Sbjct: 694 ANGVCENLRGSYRCVCNLGYEAGASGKDCTD 724
Score = 34.7 bits (78), Expect = 0.10
Identities = 30/90 (33%), Positives = 39/90 (43%), Gaps = 20/90 (22%)
Query: 92 THAVCCQGWKKRHPGALTCEAICAKPCLNGGVCVRPD-QCEC---APGW-----GGKHCH 142
T +CC + CEA C P + PD Q C APG+ GK
Sbjct: 1670 TRKMCCCSYNIGQAWNRPCEA-CPTP-------ISPDYQILCGNQAPGFLTDIHTGKP-- 1719
Query: 143 VDVDECRTSITLCSHH-CFNTAGSFTCGCP 171
+D+DEC +C++ C N GSF C CP
Sbjct: 1720 LDIDECGEIPAICANGICINQIGSFRCECP 1749
Score = 33.9 bits (76), Expect = 0.17
Identities = 28/88 (31%), Positives = 35/88 (39%), Gaps = 26/88 (29%)
Query: 92 THAVCC----QGWKKRHPGALTCEAICAKP--CLNGGVC-VRPDQCECAPGWGGKHCHVD 144
T A+CC + W L CE A+P C G + + C+ D
Sbjct: 206 TKALCCATVGRAW------GLPCELCPAQPHPCRRGFIPNIHTGACQ------------D 247
Query: 145 VDECRTSITLCSH-HCFNTAGSFTCGCP 171
VDEC+ LC C N GSF C CP
Sbjct: 248 VDECQAVPGLCQGGSCVNMVGSFHCRCP 275
Score = 30.8 bits (68), Expect = 1.5
Identities = 30/90 (33%), Positives = 37/90 (41%), Gaps = 18/90 (20%)
Query: 96 CCQGWKKRHPGAL-TCEAI--CA-KPCLNGGVCVRPDQ---CECAPGW----GGKHCHVD 144
C G++ PG + TCE I C+ P L C + C C G+ G C D
Sbjct: 2152 CADGFE---PGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCR-D 2207
Query: 145 VDECRTSITLC---SHHCFNTAGSFTCGCP 171
VDEC C C N G+F C CP
Sbjct: 2208 VDECADGQQDCHARGMECKNLIGTFACVCP 2237
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 63.5 bits (153), Expect = 2e-10
Identities = 39/99 (39%), Positives = 46/99 (46%), Gaps = 10/99 (10%)
Query: 115 AKPCLNGGVCVRPD---QCECAPGWGGKHCHVDVDECRTSITLC--SHHCFNTAGSFTCG 169
A PC+NGGVC+ QC C PG+ G C DV+EC C C NT GSF C
Sbjct: 162 ANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCL 221
Query: 170 CPHDLVLGVDGRTC-MEGSPEPPTSASILSVAVREAEKD 207
CP +G +G C + P PP S EKD
Sbjct: 222 CP----VGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKD 256
Score = 52.4 bits (124), Expect = 5e-07
Identities = 32/94 (34%), Positives = 43/94 (45%), Gaps = 8/94 (8%)
Query: 93 HAVCCQGWKKRHPGALTCEAICAKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECR 149
H +C G + + T E A PCLN C + QC C PG+ G C D+DECR
Sbjct: 498 HCLCPPGLEGQLCEVETNECASA-PCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECR 556
Query: 150 TSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTC 183
+S C + G+F C C + G +G C
Sbjct: 557 SSPCANGGQCQDQPGAFHCKC----LPGFEGPRC 586
Score = 52.4 bits (124), Expect = 5e-07
Identities = 30/94 (31%), Positives = 48/94 (51%), Gaps = 10/94 (10%)
Query: 115 AKPCLNGGVCVRPDQ---CECAPGWGGKHCHVDVDECRTSITLCSHH--CFNTAGSFTCG 169
++PC NG C+ C+CAPG+ G++C ++D C++ C +H C G F C
Sbjct: 936 SRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQ--PCHNHGTCTPKPGGFHCA 993
Query: 170 CPHDLV-LGVDGRT--CMEGSPEPPTSASILSVA 200
CP V L +G C++ P +A+ S+A
Sbjct: 994 CPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLA 1027
Score = 52.0 bits (123), Expect = 6e-07
Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 3/65 (4%)
Query: 110 CEAICAKPCLNGGVCVRPD---QCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSF 166
CE C NGG C C C GWGG C ++D+C + C + GSF
Sbjct: 318 CETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSF 377
Query: 167 TCGCP 171
+C CP
Sbjct: 378 SCLCP 382
Score = 52.0 bits (123), Expect = 6e-07
Identities = 27/74 (36%), Positives = 35/74 (47%), Gaps = 11/74 (14%)
Query: 115 AKPCLNGGVCVRPDQ-----CECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCG 169
+ PC NGG C DQ C+C PG+ G C +VDEC + C + G+F C
Sbjct: 557 SSPCANGGQC--QDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCL 614
Query: 170 CPHDLVLGVDGRTC 183
CP G G+ C
Sbjct: 615 CPS----GFTGQLC 624
Score = 48.5 bits (114), Expect = 7e-06
Identities = 22/47 (46%), Positives = 26/47 (55%), Gaps = 5/47 (10%)
Query: 130 CECAPGWGGKHCHVDVDEC---RTSITLCSH--HCFNTAGSFTCGCP 171
C C PG+ G CH D+DEC + + C H C NT GSF C CP
Sbjct: 418 CLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCP 464
Score = 45.4 bits (106), Expect = 6e-05
Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 10/83 (12%)
Query: 117 PCLNGGVCVRPDQ----CECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPH 172
PCLNGG C P C C P G C D C ++ C N G+F+C C
Sbjct: 737 PCLNGGSC-NPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLC-- 793
Query: 173 DLVLGVDGRTCMEGSPEPPTSAS 195
+G G C EG P + S
Sbjct: 794 --AMGFQGPRC-EGKLRPSCADS 813
Score = 45.4 bits (106), Expect = 6e-05
Identities = 23/62 (37%), Positives = 30/62 (48%), Gaps = 7/62 (11%)
Query: 130 CECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGS---FTCGCPHDLVLGVDGRTCMEG 186
C+C PG G+ C V++D C + C TAGS F C CP G +G TC
Sbjct: 1032 CQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPK----GFEGPTCSHR 1087
Query: 187 SP 188
+P
Sbjct: 1088 AP 1089
Score = 45.1 bits (105), Expect = 8e-05
Identities = 30/74 (40%), Positives = 34/74 (45%), Gaps = 10/74 (13%)
Query: 118 CLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRT-SITLCSH--HCFNTAGSFTCGCP 171
C NGG C + C C W G C DVDEC T C + C N+AGSF C C
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVC- 343
Query: 172 HDLVLGVDGRTCME 185
V G G +C E
Sbjct: 344 ---VSGWGGTSCEE 354
Score = 45.1 bits (105), Expect = 8e-05
Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 7/70 (10%)
Query: 117 PCLNGGVCVRPD---QCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHD 173
PC +GG C+ C C PG+ G C D +EC + C + +F C CP
Sbjct: 445 PCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPP- 503
Query: 174 LVLGVDGRTC 183
G++G+ C
Sbjct: 504 ---GLEGQLC 510
Score = 43.1 bits (100), Expect = 3e-04
Identities = 28/103 (27%), Positives = 37/103 (35%), Gaps = 16/103 (15%)
Query: 93 HAVCCQGW---------KKRHPGALTCEAICAKPCLNGGVCVRPDQ---CECAPGWGGKH 140
H +C QGW AL+ + C NGG+CV C C PG+ G
Sbjct: 867 HCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSL 926
Query: 141 CHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTC 183
C V+ C + C + C C G DG+ C
Sbjct: 927 CQDHVNPCESRPCQNGATCMAQPSGYLCQC----APGYDGQNC 965
Score = 42.7 bits (99), Expect = 4e-04
Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 4/85 (4%)
Query: 90 QQTHAVCCQGWKKRHPGALTCEAICAKPCLNGGVCV-RPD--QCECAPGWGGKHCHVDVD 146
Q++ VC GW A I A PC +GG C +P C C G+ G C ++
Sbjct: 673 QRSSCVCDVGWTGPECEAELGGCISA-PCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMT 731
Query: 147 ECRTSITLCSHHCFNTAGSFTCGCP 171
C + L C + G + C CP
Sbjct: 732 ACHSGPCLNGGSCNPSPGGYYCTCP 756
Score = 38.1 bits (87), Expect = 0.009
Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 7/61 (11%)
Query: 118 CLNGGVC-VRPDQ------CECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGC 170
C NGG C + P++ C C PG+ G C V+ D C + C + ++TC C
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC 302
Query: 171 P 171
P
Sbjct: 303 P 303
Score = 37.4 bits (85), Expect = 0.016
Identities = 22/76 (28%), Positives = 29/76 (38%), Gaps = 9/76 (11%)
Query: 114 CAKP----CLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCG 169
CA P + G C R C C GW G C ++ C ++ C+ + C
Sbjct: 658 CAPPEDNCTCHHGHCQR-SSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCT 716
Query: 170 CPHDLVLGVDGRTCME 185
CP G G TC E
Sbjct: 717 CP----TGYTGPTCSE 728
Score = 36.6 bits (83), Expect = 0.027
Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 4/61 (6%)
Query: 114 CA-KPCLNGGVCVRPDQ---CECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCG 169
CA PC N C Q C C G+ G C +D C + HC T SF C
Sbjct: 810 CADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCL 869
Query: 170 C 170
C
Sbjct: 870 C 870
Score = 35.0 bits (79), Expect = 0.078
Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 7/57 (12%)
Query: 105 PGALTCEAICAKPCLNGGVCVR----PDQCECAPGWGGKHCHVDVDECRTSITLCSH 157
P L C + +PC NGG C+ C+CAPG+ G+ C D C+ + LC +
Sbjct: 23 PRGLLCGSF-PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNA-QLCQN 76
Score = 32.7 bits (73), Expect = 0.39
Identities = 22/68 (32%), Positives = 28/68 (41%), Gaps = 13/68 (19%)
Query: 118 CLNGGVCVR------PDQCECAPGWGGKHCHVD--VDEC-RTSITLCSHHCFNTAG---- 164
C +GG+C+ P +C C G+GG C C S L + C T G
Sbjct: 1096 CHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGP 1155
Query: 165 SFTCGCPH 172
F C CPH
Sbjct: 1156 GFRCSCPH 1163
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 63.5 bits (153), Expect = 2e-10
Identities = 40/131 (30%), Positives = 59/131 (45%), Gaps = 11/131 (8%)
Query: 33 ESQGVCSK-QTLVVPLHYNESYSQPVYKPYLTLCAGRRI---CSTYRTMYRVMWREVRRE 88
E VCS ++ V + ESY+ P + Y T C C+ +R Y+ +R R
Sbjct: 23 EDPNVCSHWESYAVTVQ--ESYAHPFDQIYYTRCTDILNWFKCTRHRISYKTAYRRGLRT 80
Query: 89 VQQTHAVCCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDEC 148
+ + + CC G+ + C +C + C++G CV PD C C PGWGG C D
Sbjct: 81 MYRRRSQCCPGY---YESGDFCIPLCTEECVHGR-CVSPDTCHCEPGWGGPDCSSGCDSD 136
Query: 149 RTSITLCSHHC 159
CS+ C
Sbjct: 137 HWG-PHCSNRC 146
Score = 37.7 bits (86), Expect = 0.012
Identities = 19/53 (35%), Positives = 22/53 (41%), Gaps = 4/53 (7%)
Query: 108 LTCEAICAKPCLNGGVCVRPD-QCECAPGWGGKHCHVDVDECRTSITLCSHHC 159
L C C C NG C D C C PGW G C + + + CS HC
Sbjct: 487 LNCNESCT--CANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLN-CSEHC 536
Score = 37.4 bits (85), Expect = 0.016
Identities = 34/129 (26%), Positives = 40/129 (31%), Gaps = 24/129 (18%)
Query: 110 CEAICAKPCLNGGVCVR-PDQCECAPGWGGKHCHVDV------DECRTSITL-----CSH 157
CE C PC NGG C +C C PGW G C C C H
Sbjct: 228 CELRC--PCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDH 285
Query: 158 ---HCFNTAGSFTCGCPHDLVLGVDGRTCME-------GSPEPPTSASILSVAVREAEKD 207
C TAG C + G G C + G P T A +
Sbjct: 286 VTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQ 345
Query: 208 ERALKQEIH 216
ER + +H
Sbjct: 346 ERLCPEGLH 354
Score = 35.8 bits (81), Expect = 0.046
Identities = 27/97 (27%), Positives = 33/97 (34%), Gaps = 26/97 (26%)
Query: 93 HAVCCQGWKKRHPGALTCEAICAK-----------PCLNGGVCVRPD-QCECAPGWGGKH 140
H C GW + C++ C C NGG C D CECAPG+ G
Sbjct: 550 HCCCLAGWT-----GIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPL 604
Query: 141 CHVDVDE------CRTSITLCSHH---CFNTAGSFTC 168
C C LC H C + +G C
Sbjct: 605 CQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICEC 641
Score = 35.0 bits (79), Expect = 0.078
Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 3/33 (9%)
Query: 110 CEAICAKPCLNGGVCVRPD-QCECAPGWGGKHC 141
C +C+ C N G C D C+C PGW GK C
Sbjct: 663 CAQLCS--CANNGTCSPIDGSCQCFPGWIGKDC 693
Score = 33.1 bits (74), Expect = 0.30
Identities = 15/33 (45%), Positives = 17/33 (51%), Gaps = 3/33 (9%)
Query: 110 CEAICAKPCLNGGVCVRPD-QCECAPGWGGKHC 141
C +IC+ C NGG C D C C GW G C
Sbjct: 446 CSSICS--CNNGGTCSPVDGSCTCKEGWQGLDC 476
Score = 31.6 bits (70), Expect = 0.87
Identities = 20/69 (28%), Positives = 24/69 (34%), Gaps = 16/69 (23%)
Query: 130 CECAPGWGGKHCHVDV------DECRTSITLCSH--HCFNTAGSFTCG-------CPHDL 174
C C PGW G HC+ D C+ T C + C + G TC C
Sbjct: 379 CTCQPGWSGHHCNESCPVGYYGDGCQLPCT-CQNGADCHSITGGCTCAPGFMGEVCAVSC 437
Query: 175 VLGVDGRTC 183
G G C
Sbjct: 438 AAGTYGPNC 446
Score = 30.8 bits (68), Expect = 1.5
Identities = 18/53 (33%), Positives = 19/53 (35%), Gaps = 7/53 (13%)
Query: 96 CCQGWKKRH------PGALTCEAICAKPCLNGGVCVRPD-QCECAPGWGGKHC 141
C GW + PG A C NG C D C C PGW G C
Sbjct: 684 CFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFC 736
Score = 29.6 bits (65), Expect = 3.3
Identities = 18/59 (30%), Positives = 25/59 (42%), Gaps = 17/59 (28%)
Query: 95 VCCQGWKKRHPGALTCEAICAK-----------PCLNGGVC-VRPDQCECAPGWGGKHC 141
VC G++ CE +CA C +G C R +C CAPG+ G +C
Sbjct: 162 VCAAGFR-----GWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYC 215
Score = 29.3 bits (64), Expect = 4.3
Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 11/55 (20%)
Query: 96 CCQGWK-----KRHPGAL---TCEAICAKPCLNGGVCVR-PDQCECAPGWGGKHC 141
C GW +R P A C +C C NG C +C C G+ G+HC
Sbjct: 727 CTPGWTGLFCTQRCPAAFFGKDCGRVCQ--CQNGASCDHISGKCTCRTGFTGQHC 779
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 62.4 bits (150), Expect = 5e-10
Identities = 30/66 (45%), Positives = 32/66 (48%), Gaps = 13/66 (19%)
Query: 96 CCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLC 155
C +GW G L E IC PCLNGG CV P QC+C PGW G CH V C
Sbjct: 3490 CPEGWM----GRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAV---------C 3536
Query: 156 SHHCFN 161
C N
Sbjct: 3537 QSPCLN 3542
Score = 53.1 bits (126), Expect = 3e-07
Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 3/60 (5%)
Query: 115 AKPCLNGGVCV---RPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCP 171
+ PCLN G+CV +C C G+ G HC +V+EC+++ L + C + G F C CP
Sbjct: 1275 SSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCP 1334
Score = 53.1 bits (126), Expect = 3e-07
Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 12/65 (18%)
Query: 110 CEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFN---TAGSF 166
C A+C PC NGG+C RP+ C C GW G+ C + C C N +
Sbjct: 3468 CRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPI---------CILPCLNGGRCVAPY 3518
Query: 167 TCGCP 171
C CP
Sbjct: 3519 QCDCP 3523
Score = 52.4 bits (124), Expect = 5e-07
Identities = 21/46 (45%), Positives = 26/46 (56%), Gaps = 4/46 (8%)
Query: 96 CCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGWGGKHC 141
C GW G+ A+C PCLNGG CVRP++C C W G +C
Sbjct: 3522 CPPGWT----GSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNC 3563
Score = 48.1 bits (113), Expect = 9e-06
Identities = 32/97 (32%), Positives = 41/97 (42%), Gaps = 8/97 (8%)
Query: 101 KKRHPGALTCEAICA-KPCLNGGVCVRPDQ---CECAPGWGGKHCHVDVDECRTSITLCS 156
KKRH + C PC N G C + + C C G+ G C D+DEC L +
Sbjct: 1184 KKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNN 1243
Query: 157 HHCFNTAGSFTCGCPHDLVLGVDGRTCMEGSPEPPTS 193
C + G F C CP G G+ C E E +S
Sbjct: 1244 GVCKDLVGEFICECPS----GYTGQRCEENINECSSS 1276
Score = 47.0 bits (110), Expect = 2e-05
Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 7/72 (9%)
Query: 115 AKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCP 171
++PC NG C +C CA G+ G HC ++++EC+++ C + S++C C
Sbjct: 1351 SQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQ 1410
Query: 172 HDLVLGVDGRTC 183
G G+ C
Sbjct: 1411 P----GFSGKRC 1418
Score = 45.8 bits (107), Expect = 4e-05
Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 3/57 (5%)
Query: 117 PCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGC 170
PCLN GVC V CEC G+ G+ C +++EC +S L C + + C C
Sbjct: 1239 PCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTC 1295
Score = 43.9 bits (102), Expect = 2e-04
Identities = 24/61 (39%), Positives = 30/61 (49%), Gaps = 7/61 (11%)
Query: 115 AKPCLNGGVCVRPDQ-----CECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCG 169
+ PCLN VC DQ C+C PG+ G C +VDEC + C + A SF C
Sbjct: 1313 SNPCLNNAVC--EDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCL 1370
Query: 170 C 170
C
Sbjct: 1371 C 1371
Score = 33.1 bits (74), Expect = 0.30
Identities = 28/85 (32%), Positives = 34/85 (40%), Gaps = 17/85 (20%)
Query: 118 CLNGGVCVRPDQCECAPG--WGG--KHCHVDVDECRTSITLCSHH--CFNTAGSFTCGCP 171
C NG + + C W G C +DVDEC CS H C N GS+ C C
Sbjct: 1716 CNNGYYLLGDSRMFCTDNGSWNGVSPSC-LDVDECAVGSD-CSEHASCLNVDGSYICSCV 1773
Query: 172 HDLVLGVDGRTCME-------GSPE 189
DG+ C E G+PE
Sbjct: 1774 PPYT--GDGKNCAEPIKCKAPGNPE 1796
Score = 31.6 bits (70), Expect = 0.87
Identities = 16/53 (30%), Positives = 22/53 (41%), Gaps = 4/53 (7%)
Query: 95 VCCQGWKKRHPGALTCEAICAKPCLNGGVCV---RPDQCECAPGWGGKHCHVD 144
+C G+ H L + PC N CV C+C PG+ GK C +
Sbjct: 1370 LCAAGFTGSHC-ELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1421
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 61.6 bits (148), Expect = 8e-10
Identities = 38/113 (33%), Positives = 55/113 (48%), Gaps = 17/113 (15%)
Query: 95 VCCQGWKKRHPGALT--CEAICAKPCLNGGVCVRPD---QCECAPGWGGKHCHVDVDECR 149
+C GW+ R T C + PC NGG+CV +CECAPG+ G C +++DEC+
Sbjct: 738 ICRDGWEGRTCTHNTNDCNPL---PCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQ 794
Query: 150 TSITLCSHHCFNTAGSFTCGCPH-------DLVLGVDGRTC-MEGSPEPPTSA 194
+S C + + C CP V+G GR+C G+P P S+
Sbjct: 795 SSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGF-GRSCWSRGTPFPHGSS 846
Score = 57.8 bits (138), Expect = 1e-08
Identities = 33/106 (31%), Positives = 43/106 (40%), Gaps = 16/106 (15%)
Query: 85 VRREVQQTHAVCCQGWKKRHPGALTCE----AICAKPCLNGGVCVRPD---QCECAPGWG 137
+ E Q C G+ R+ CE A + PC NGG C +C C GW
Sbjct: 324 INAEPDQYRCTCPDGYSGRN-----CEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWS 378
Query: 138 GKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTC 183
G C +D+DEC ++ C + F C CP V G TC
Sbjct: 379 GPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWV----GATC 420
Score = 55.8 bits (133), Expect = 4e-08
Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 8/92 (8%)
Query: 95 VCCQGWKKRHPGALTCEAICAKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTS 151
VC +G+ RH L + + PC +GG+C C C G+ G C VDVD C S
Sbjct: 447 VCPRGFGGRHC-ELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPS 505
Query: 152 ITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTC 183
C+N G + C CP D G+ C
Sbjct: 506 PCRNGARCYNLEGDYYCACPDDF----GGKNC 533
Score = 52.8 bits (125), Expect = 4e-07
Identities = 32/102 (31%), Positives = 43/102 (42%), Gaps = 15/102 (14%)
Query: 88 EVQQTHAVCCQGWKKRHPGALTCEAI---CAKPCLNGGVC---VRPDQCECAPGWGGKHC 141
+V +C + W TC+ C C +GG C V QC C G+GG+HC
Sbjct: 403 QVDGFECICPEQWV-----GATCQLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHC 457
Query: 142 HVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTC 183
++ DEC +S C + A F C CP G G C
Sbjct: 458 ELERDECASSPCHSGGLCEDLADGFHCHCPQ----GFSGPLC 495
Score = 50.1 bits (118), Expect = 2e-06
Identities = 32/101 (31%), Positives = 42/101 (41%), Gaps = 13/101 (12%)
Query: 89 VQQTHAVCCQGWKKR--HPGALTCEAICAKPCLNGGVCVRPD---QCECAPGWGGKHCHV 143
V + C GWK + H C+A C NGG C +C C PGW G C V
Sbjct: 655 VNDFYCACDDGWKGKTCHSREFQCDAYT---CSNGGTCYDSGDTFRCACPPGWKGSTCAV 711
Query: 144 DVD-ECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTC 183
+ C + + C + SF+C C G +GRTC
Sbjct: 712 AKNSSCLPNPCVNGGTCVGSGASFSCICRD----GWEGRTC 748
Score = 47.8 bits (112), Expect = 1e-05
Identities = 31/96 (32%), Positives = 36/96 (37%), Gaps = 23/96 (23%)
Query: 96 CCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLC 155
C GW+ R C+ P G CV P QC C WGG C D++ C
Sbjct: 264 CSYGWQGRF-----CDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCG------ 312
Query: 156 SHH-------CFNT-AGSFTCGCPHDLVLGVDGRTC 183
SHH C N + C CP G GR C
Sbjct: 313 SHHPCTNGGTCINAEPDQYRCTCPD----GYSGRNC 344
Score = 45.1 bits (105), Expect = 8e-05
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 7/71 (9%)
Query: 116 KPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPH 172
+PC NGG C V +C C GW G+ C + ++C C++ F C C
Sbjct: 605 QPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDD 664
Query: 173 DLVLGVDGRTC 183
G G+TC
Sbjct: 665 ----GWKGKTC 671
Score = 43.9 bits (102), Expect = 2e-04
Identities = 28/99 (28%), Positives = 37/99 (37%), Gaps = 8/99 (8%)
Query: 88 EVQQTHAVCCQGWKKRHPGALTCEAICAKPCLNGGVC---VRPDQCECAPGWGGKHCHVD 144
EV C GW+ + + PC + G C V C C GW GK CH
Sbjct: 616 EVDAFRCFCPSGWEGELCDTNPNDCL-PDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSR 674
Query: 145 VDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTC 183
+C C+++ +F C CP G G TC
Sbjct: 675 EFQCDAYTCSNGGTCYDSGDTFRCACPP----GWKGSTC 709
Score = 43.1 bits (100), Expect = 3e-04
Identities = 39/139 (28%), Positives = 51/139 (36%), Gaps = 31/139 (22%)
Query: 90 QQTHAVCCQGWKKRHPGALTCEAICAKPC--LNGGVCVRPDQCECAPGWGGKHCHVDVDE 147
Q + C GW G EA+C + C L+GG C P +C C+ GW G+ C DE
Sbjct: 225 QYGNKACMDGWM----GKECKEAVCKQGCNLLHGG-CTVPGECRCSYGWQGRFC----DE 275
Query: 148 CRTSITLCSH---------HCFNTAGSFT-------CGCPHDLVLGVDGRTCMEGSPEPP 191
C C H +C G CG H +G TC+ P+
Sbjct: 276 C-VPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPC---TNGGTCINAEPDQY 331
Query: 192 TSASILSVAVREAEKDERA 210
+ R EK E A
Sbjct: 332 RCTCPDGYSGRNCEKAEHA 350
Score = 36.2 bits (82), Expect = 0.035
Identities = 16/54 (29%), Positives = 24/54 (44%), Gaps = 4/54 (7%)
Query: 130 CECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTC 183
C C G+ G +CH ++D+C C + +F C CP G +G C
Sbjct: 584 CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPS----GWEGELC 633
Score = 34.7 bits (78), Expect = 0.10
Identities = 30/96 (31%), Positives = 37/96 (38%), Gaps = 12/96 (12%)
Query: 93 HAVCCQGWKKRHPGALTCEA---ICA-KPCLNGGVCVRPD---QCECAPGWGGKHCHVDV 145
H C QG+ G L CE +C PC NG C + C C +GGK+C V
Sbjct: 483 HCHCPQGFS----GPL-CEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPR 537
Query: 146 DECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGR 181
+ C C + AG G V G GR
Sbjct: 538 EPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGR 573
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 61.6 bits (148), Expect = 8e-10
Identities = 38/113 (33%), Positives = 55/113 (48%), Gaps = 17/113 (15%)
Query: 95 VCCQGWKKRHPGALT--CEAICAKPCLNGGVCVRPD---QCECAPGWGGKHCHVDVDECR 149
+C GW+ R T C + PC NGG+CV +CECAPG+ G C +++DEC+
Sbjct: 776 ICRDGWEGRTCTHNTNDCNPL---PCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQ 832
Query: 150 TSITLCSHHCFNTAGSFTCGCPH-------DLVLGVDGRTC-MEGSPEPPTSA 194
+S C + + C CP V+G GR+C G+P P S+
Sbjct: 833 SSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGF-GRSCWSRGTPFPHGSS 884
Score = 58.2 bits (139), Expect = 9e-09
Identities = 36/117 (30%), Positives = 46/117 (39%), Gaps = 22/117 (18%)
Query: 85 VRREVQQTHAVCCQGWKKRHPGALTCE----AICAKPCLNGGVCVRPD---QCECAPGWG 137
+ E Q C G+ R+ CE A + PC NGG C +C C GW
Sbjct: 324 INAEPDQYRCTCPDGYSGRN-----CEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWS 378
Query: 138 GKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCM------EGSP 188
G C +D+DEC ++ C + F C CP V G TC EG P
Sbjct: 379 GPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWV----GATCQLDANECEGKP 431
Score = 55.8 bits (133), Expect = 4e-08
Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 8/92 (8%)
Query: 95 VCCQGWKKRHPGALTCEAICAKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTS 151
VC +G+ RH L + + PC +GG+C C C G+ G C VDVD C S
Sbjct: 485 VCPRGFGGRHC-ELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPS 543
Query: 152 ITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTC 183
C+N G + C CP D G+ C
Sbjct: 544 PCRNGARCYNLEGDYYCACPDDF----GGKNC 571
Score = 54.7 bits (130), Expect = 1e-07
Identities = 32/94 (34%), Positives = 40/94 (42%), Gaps = 15/94 (15%)
Query: 96 CCQGWKKRHPGALTCEAI---CAKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECR 149
C GWK + C C C +GG C V QC C G+GG+HC ++ DEC
Sbjct: 449 CIPGWK-----GINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECA 503
Query: 150 TSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTC 183
+S C + A F C CP G G C
Sbjct: 504 SSPCHSGGLCEDLADGFHCHCPQ----GFSGPLC 533
Score = 53.1 bits (126), Expect = 3e-07
Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 12/73 (16%)
Query: 116 KPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSH--HCFNTAGSFTCGC 170
KPCLN C + C+C PGW G +CH++V++CR C H C + + C C
Sbjct: 430 KPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQ---CQHGGTCKDLVNGYQCVC 486
Query: 171 PHDLVLGVDGRTC 183
P G GR C
Sbjct: 487 PR----GFGGRHC 495
Score = 50.1 bits (118), Expect = 2e-06
Identities = 32/101 (31%), Positives = 42/101 (41%), Gaps = 13/101 (12%)
Query: 89 VQQTHAVCCQGWKKR--HPGALTCEAICAKPCLNGGVCVRPD---QCECAPGWGGKHCHV 143
V + C GWK + H C+A C NGG C +C C PGW G C V
Sbjct: 693 VNDFYCACDDGWKGKTCHSREFQCDAYT---CSNGGTCYDSGDTFRCACPPGWKGSTCAV 749
Query: 144 DVD-ECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTC 183
+ C + + C + SF+C C G +GRTC
Sbjct: 750 AKNSSCLPNPCVNGGTCVGSGASFSCICRD----GWEGRTC 786
Score = 47.8 bits (112), Expect = 1e-05
Identities = 31/96 (32%), Positives = 36/96 (37%), Gaps = 23/96 (23%)
Query: 96 CCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLC 155
C GW+ R C+ P G CV P QC C WGG C D++ C
Sbjct: 264 CSYGWQGRF-----CDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCG------ 312
Query: 156 SHH-------CFNT-AGSFTCGCPHDLVLGVDGRTC 183
SHH C N + C CP G GR C
Sbjct: 313 SHHPCTNGGTCINAEPDQYRCTCPD----GYSGRNC 344
Score = 47.4 bits (111), Expect = 2e-05
Identities = 25/78 (32%), Positives = 32/78 (41%), Gaps = 4/78 (5%)
Query: 96 CCQGWKKRHPGALTCEAICAKPCLNGGVCVRPD---QCECAPGWGGKHCHVDVDECRTSI 152
C GW AL + + PC GG CV +C C W G C +D +EC
Sbjct: 373 CPSGWSGP-TCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKP 431
Query: 153 TLCSHHCFNTAGSFTCGC 170
L + C N G + C C
Sbjct: 432 CLNAFSCKNLIGGYYCDC 449
Score = 45.1 bits (105), Expect = 8e-05
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 7/71 (9%)
Query: 116 KPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPH 172
+PC NGG C V +C C GW G+ C + ++C C++ F C C
Sbjct: 643 QPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDD 702
Query: 173 DLVLGVDGRTC 183
G G+TC
Sbjct: 703 ----GWKGKTC 709
Score = 43.9 bits (102), Expect = 2e-04
Identities = 28/99 (28%), Positives = 37/99 (37%), Gaps = 8/99 (8%)
Query: 88 EVQQTHAVCCQGWKKRHPGALTCEAICAKPCLNGGVC---VRPDQCECAPGWGGKHCHVD 144
EV C GW+ + + PC + G C V C C GW GK CH
Sbjct: 654 EVDAFRCFCPSGWEGELCDTNPNDCL-PDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSR 712
Query: 145 VDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTC 183
+C C+++ +F C CP G G TC
Sbjct: 713 EFQCDAYTCSNGGTCYDSGDTFRCACPP----GWKGSTC 747
Score = 43.1 bits (100), Expect = 3e-04
Identities = 39/139 (28%), Positives = 51/139 (36%), Gaps = 31/139 (22%)
Query: 90 QQTHAVCCQGWKKRHPGALTCEAICAKPC--LNGGVCVRPDQCECAPGWGGKHCHVDVDE 147
Q + C GW G EA+C + C L+GG C P +C C+ GW G+ C DE
Sbjct: 225 QYGNKACMDGWM----GKECKEAVCKQGCNLLHGG-CTVPGECRCSYGWQGRFC----DE 275
Query: 148 CRTSITLCSH---------HCFNTAGSFT-------CGCPHDLVLGVDGRTCMEGSPEPP 191
C C H +C G CG H +G TC+ P+
Sbjct: 276 C-VPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPC---TNGGTCINAEPDQY 331
Query: 192 TSASILSVAVREAEKDERA 210
+ R EK E A
Sbjct: 332 RCTCPDGYSGRNCEKAEHA 350
Score = 36.2 bits (82), Expect = 0.035
Identities = 16/54 (29%), Positives = 24/54 (44%), Gaps = 4/54 (7%)
Query: 130 CECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTC 183
C C G+ G +CH ++D+C C + +F C CP G +G C
Sbjct: 622 CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPS----GWEGELC 671
Score = 34.7 bits (78), Expect = 0.10
Identities = 30/96 (31%), Positives = 37/96 (38%), Gaps = 12/96 (12%)
Query: 93 HAVCCQGWKKRHPGALTCEA---ICA-KPCLNGGVCVRPD---QCECAPGWGGKHCHVDV 145
H C QG+ G L CE +C PC NG C + C C +GGK+C V
Sbjct: 521 HCHCPQGFS----GPL-CEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPR 575
Query: 146 DECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGR 181
+ C C + AG G V G GR
Sbjct: 576 EPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGR 611
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 61.2 bits (147), Expect = 1e-09
Identities = 35/107 (32%), Positives = 48/107 (44%), Gaps = 24/107 (22%)
Query: 95 VCCQGWKKRHPGALTCEAICAK--------PCLNGGVCVRPD---QCECAPGWGGKHCHV 143
VC +GW+ ICA+ PC N G CV D +CECAPG+ G C +
Sbjct: 769 VCKEGWEG---------PICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRI 819
Query: 144 DVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCMEGSPEP 190
+++EC++S C + + C CP G G C E S P
Sbjct: 820 NINECQSSPCAFGATCVDEINGYRCVCPP----GHSGAKCQEVSGRP 862
Score = 55.5 bits (132), Expect = 6e-08
Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 7/72 (9%)
Query: 115 AKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCP 171
+ PCLNGG C + QC C G+ G C +D+D C + C+N A + C CP
Sbjct: 493 SNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCP 552
Query: 172 HDLVLGVDGRTC 183
D +G+ C
Sbjct: 553 ED----YEGKNC 560
Score = 54.3 bits (129), Expect = 1e-07
Identities = 27/73 (36%), Positives = 32/73 (43%), Gaps = 7/73 (9%)
Query: 114 CAKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGC 170
C C N C V +C C PG+ G HC D+DEC ++ L HC N F C C
Sbjct: 454 CLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLC 513
Query: 171 PHDLVLGVDGRTC 183
P G G C
Sbjct: 514 P----TGFSGNLC 522
Score = 53.9 bits (128), Expect = 2e-07
Identities = 32/102 (31%), Positives = 44/102 (43%), Gaps = 16/102 (15%)
Query: 89 VQQTHAVCCQGWKKRHPGALTCEAI---CAK-PCLNGGVC---VRPDQCECAPGWGGKHC 141
V +C GW+ + CE C++ PC NGG C V C+C GW GK C
Sbjct: 648 VNSYKCICSDGWEGAY-----CETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTC 702
Query: 142 HVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTC 183
H +C + C++ +F C CP G +G TC
Sbjct: 703 HSRDSQCDEATCNNGGTCYDEGDAFKCMCPG----GWEGTTC 740
Score = 52.0 bits (123), Expect = 6e-07
Identities = 32/94 (34%), Positives = 42/94 (44%), Gaps = 14/94 (14%)
Query: 96 CCQGWKKRHPGALTCEAIC-AKPCLNGGVCVRPD---QCECAPGWGGKHCHVDVDECRTS 151
C +G+ P E C + PC N G C +CEC+PGW G C ++D+C S
Sbjct: 324 CPEGYSG--PNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDC--S 379
Query: 152 ITLCSH--HCFNTAGSFTCGCPHDLVLGVDGRTC 183
CSH C + F C CP G+TC
Sbjct: 380 PNNCSHGGTCQDLVNGFKCVCPPQWT----GKTC 409
Score = 48.5 bits (114), Expect = 7e-06
Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 10/83 (12%)
Query: 104 HPGALTCEAICAKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCF 160
H CE+ PC NGG C V +C C+ GW G +C ++++C + C
Sbjct: 627 HENINDCES---NPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCR 683
Query: 161 NTAGSFTCGCPHDLVLGVDGRTC 183
+ F C C + G G+TC
Sbjct: 684 DLVNDFYCDCKN----GWKGKTC 702
Score = 47.4 bits (111), Expect = 2e-05
Identities = 33/106 (31%), Positives = 41/106 (38%), Gaps = 20/106 (18%)
Query: 94 AVCCQGWKKRH-----PG---------ALTCEAICAKPCLNGGVCVRPDQCECAPGWGGK 139
A+C QG +H PG L C+ P G+C P QC C WGG+
Sbjct: 232 AICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQ 291
Query: 140 HCHVDVDECRT-SITLCSHHCFNTA-GSFTCGCPHDLVLGVDGRTC 183
C D++ C T L C NT + C CP G G C
Sbjct: 292 LCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPE----GYSGPNC 333
Score = 47.0 bits (110), Expect = 2e-05
Identities = 26/79 (32%), Positives = 34/79 (43%), Gaps = 6/79 (7%)
Query: 96 CCQGWKKRHPGALTCEAICA-KPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTS 151
C GW P T C+ C +GG C V +C C P W GK C +D +EC
Sbjct: 362 CSPGWTG--PTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK 419
Query: 152 ITLCSHHCFNTAGSFTCGC 170
+ + C N S+ C C
Sbjct: 420 PCVNAKSCKNLIASYYCDC 438
Score = 45.1 bits (105), Expect = 8e-05
Identities = 31/103 (30%), Positives = 43/103 (41%), Gaps = 16/103 (15%)
Query: 93 HAVCCQGWK---KRHPGALTCEA---ICA--KPCLNGGVCVR--PD--QCECAPGWGGKH 140
H +C + W+ + + G C+ C +PCLNGG C PD QC C G+ G +
Sbjct: 273 HGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPN 332
Query: 141 CHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTC 183
C + C + C T+ F C C G G TC
Sbjct: 333 CEIAEHACLSDPCHNRGSCKETSLGFECECSP----GWTGPTC 371
Score = 39.7 bits (91), Expect = 0.003
Identities = 21/79 (26%), Positives = 30/79 (37%), Gaps = 3/79 (3%)
Query: 95 VCCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQ---CECAPGWGGKHCHVDVDECRTS 151
+C GW+ + PC NGG CV + C C GW G C + ++C
Sbjct: 730 MCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPH 789
Query: 152 ITLCSHHCFNTAGSFTCGC 170
S C + + C C
Sbjct: 790 PCYNSGTCVDGDNWYRCEC 808
Score = 37.0 bits (84), Expect = 0.021
Identities = 31/112 (27%), Positives = 41/112 (36%), Gaps = 17/112 (15%)
Query: 89 VQQTHAVCCQGWKKR--HPGALTCEAICAKPCLNGGVCVRPD---QCECAPGWGGKHCHV 143
V + C GWK + H C+ C NGG C +C C GW G C++
Sbjct: 686 VNDFYCDCKNGWKGKTCHSRDSQCDEAT---CNNGGTCYDEGDAFKCMCPGGWEGTTCNI 742
Query: 144 DVD-ECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCMEG----SPEP 190
+ C + C SFTC C G +G C + SP P
Sbjct: 743 ARNSSCLPNPCHNGGTCVVNGESFTCVCKE----GWEGPICAQNTNDCSPHP 790
Score = 34.3 bits (77), Expect = 0.13
Identities = 11/41 (26%), Positives = 22/41 (53%)
Query: 130 CECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGC 170
C+C G+ G +CH ++++C ++ C + S+ C C
Sbjct: 615 CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCIC 655
Score = 30.4 bits (67), Expect = 1.9
Identities = 14/38 (36%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Query: 117 PCLNGGVCVRPDQ---CECAPGWGGKHCHVDVDECRTS 151
PC NG C C+C + GK+C D CRT+
Sbjct: 533 PCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTT 570
>gi|189491647 fibulin 7 isoform 2 [Homo sapiens]
Length = 393
Score = 61.2 bits (147), Expect = 1e-09
Identities = 47/145 (32%), Positives = 58/145 (40%), Gaps = 17/145 (11%)
Query: 56 PVYKPYLTLCA-GRRICSTYRTMYRVMW--REVRREVQQTHAVCCQG--WKKRHPGALTC 110
PV P L A GR+ S Y + V + R V + VC W P
Sbjct: 78 PVSCPALNTPADGRKFGSKYLVDHEVHFTCNPGFRLVGPSSVVCLPNGTWTGEQPHCRGI 137
Query: 111 EAICAKPCLNGGVCVR---PDQCECAPGWGGKHCH----VDVDECRT-----SITLCSHH 158
++PC NGG CV +C C PG G C DV+EC LC H
Sbjct: 138 SECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTDVNECELYGQEGRPRLCMHA 197
Query: 159 CFNTAGSFTCGCPHDLVLGVDGRTC 183
C NT GS+ C CP DG++C
Sbjct: 198 CVNTPGSYRCTCPGGYRTLADGKSC 222
Score = 35.4 bits (80), Expect = 0.060
Identities = 28/81 (34%), Positives = 32/81 (39%), Gaps = 20/81 (24%)
Query: 113 ICAKPCLNGGVCVRPDQCECAPGW----GGKHCHVDVDECRTSITLCSHH--CFNTAGSF 166
+C C+N R C C G+ GK C DVDEC +C C NT GSF
Sbjct: 193 LCMHACVNTPGSYR---CTCPGGYRTLADGKSCE-DVDECVGLQPVCPQGTTCINTGGSF 248
Query: 167 TCGCPHDLVLGVDGRTCMEGS 187
C P C EGS
Sbjct: 249 QCVSPE----------CPEGS 259
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 60.8 bits (146), Expect = 1e-09
Identities = 40/113 (35%), Positives = 50/113 (44%), Gaps = 19/113 (16%)
Query: 65 CAGRRICSTYRTMYRVMWREVRREVQQTHAVCCQGWKKRHPGALTCEAICAKPCLNGGVC 124
CAGR +C + V + C +G+ R P + + PC +G C
Sbjct: 87 CAGRGVCQS----------SVVAGTARFSCRCPRGF--RGPDCSLPDPCLSSPCAHGARC 134
Query: 125 -VRPDQ---CECAPGWGGKHCHVDVDECRTSITLCSH--HCFNTAGSFTCGCP 171
V PD C C PG+ G+ C DVDECR C H C NT GSF C CP
Sbjct: 135 SVGPDGRFLCSCPPGYQGRSCRSDVDECRVG-EPCRHGGTCLNTPGSFRCQCP 186
Score = 59.3 bits (142), Expect = 4e-09
Identities = 31/81 (38%), Positives = 40/81 (49%), Gaps = 9/81 (11%)
Query: 118 CLNGGVCV---RPDQCECAPGWGGKHCHVDVDECRTSITLCSH--HCFNTAGSFTCGCPH 172
CLNGG CV C+C P W G+ C DVDEC+ C + CFNT G +C C
Sbjct: 245 CLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVC-- 302
Query: 173 DLVLGVDGRTCMEGSPEPPTS 193
V G G +C + + T+
Sbjct: 303 --VNGWTGESCSQNIDDCATA 321
Score = 52.4 bits (124), Expect = 5e-07
Identities = 31/76 (40%), Positives = 35/76 (46%), Gaps = 8/76 (10%)
Query: 117 PCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHD 173
PCLNGG C V C C PG+ G C DVDEC S C + SFTC CP
Sbjct: 857 PCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDEC-LSNPCGPGTCTDHVASFTCTCPP- 914
Query: 174 LVLGVDGRTCMEGSPE 189
G G C + P+
Sbjct: 915 ---GYGGFHCEQDLPD 927
Score = 52.4 bits (124), Expect = 5e-07
Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 12/86 (13%)
Query: 93 HAVCCQGWKKRHPGALTCEA----ICAKPCLNGGVC---VRPDQCECAPGWGGKHCHVDV 145
+ VC +G H CE A+PC +GG C + CEC PG+ G +C DV
Sbjct: 1069 YCVCPEGRTGSH-----CEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDV 1123
Query: 146 DECRTSITLCSHHCFNTAGSFTCGCP 171
DEC + C + + C CP
Sbjct: 1124 DECASQPCQHGGSCIDLVARYLCSCP 1149
Score = 52.0 bits (123), Expect = 6e-07
Identities = 34/87 (39%), Positives = 38/87 (43%), Gaps = 15/87 (17%)
Query: 93 HAVCCQGWKKRHPGALTCEAICA---KPCLNGGVCVR-PDQ---CECAPGWGGKHCHVDV 145
H C G + R CE + PC +GG C P Q C C GW G C DV
Sbjct: 757 HCTCPPGVQGRQ-----CELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDV 811
Query: 146 DECRTSITLCSHH--CFNTAGSFTCGC 170
DEC C H C N AGSF+C C
Sbjct: 812 DEC-AGPAPCGPHGICTNLAGSFSCTC 837
Score = 51.2 bits (121), Expect = 1e-06
Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 7/69 (10%)
Query: 118 CLNGGVCVRP---DQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDL 174
C NGG C C C GW G+ C ++D+C T++ C + SF C CP
Sbjct: 285 CHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACP--- 341
Query: 175 VLGVDGRTC 183
+G G C
Sbjct: 342 -MGKTGLLC 349
Score = 50.8 bits (120), Expect = 1e-06
Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
Query: 115 AKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCP 171
+ PC+NGGVC V C C G+ G C +DVDEC ++ C + + C C
Sbjct: 475 SSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCA 534
Query: 172 HDLVLGVDGRTCMEGSPEP 190
+ R + SP+P
Sbjct: 535 EGFEGTLCDRNVDDCSPDP 553
Score = 50.4 bits (119), Expect = 2e-06
Identities = 26/67 (38%), Positives = 30/67 (44%), Gaps = 7/67 (10%)
Query: 111 EAICAKPCLNGGVC-VRPDQ----CECAPGWGGKHCHVDVDECRTSITLCSH--HCFNTA 163
+A + PC +C P C C PG+ G C DVDEC C H C NT
Sbjct: 353 DACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQ 412
Query: 164 GSFTCGC 170
GSF C C
Sbjct: 413 GSFLCQC 419
Score = 50.1 bits (118), Expect = 2e-06
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 9/81 (11%)
Query: 114 CA-KPCLNGGVCVRPDQ----CECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTC 168
CA PC NGG C + C C PG+ G++C V+VD+C L C + ++ C
Sbjct: 201 CAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNC 260
Query: 169 GCPHDLVLGVDGRTCMEGSPE 189
CP + G+ C E E
Sbjct: 261 QCPPEWT----GQFCTEDVDE 277
Score = 48.9 bits (115), Expect = 5e-06
Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 7/70 (10%)
Query: 117 PCLNGGVCV-RPDQ--CECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHD 173
PC N C+ R Q C C G+ G +C VD+DEC++S + C + F+C CP
Sbjct: 439 PCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPS- 497
Query: 174 LVLGVDGRTC 183
G G TC
Sbjct: 498 ---GFSGSTC 504
Score = 45.8 bits (107), Expect = 4e-05
Identities = 30/98 (30%), Positives = 39/98 (39%), Gaps = 15/98 (15%)
Query: 105 PGALTCEAICAKPCLNGGVCV----RPDQCECAPGWGGKHCHVDVDECRTSIT----LCS 156
PGA + PC NGG C R C C PGW G+ C ++ D C + +C
Sbjct: 36 PGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGPCAGRGVCQ 94
Query: 157 HHCFNTAGSFTCGCPHDLVLGVDGRTCMEGSPEPPTSA 194
F+C CP G G C P+P S+
Sbjct: 95 SSVVAGTARFSCRCPR----GFRGPDC--SLPDPCLSS 126
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 7/75 (9%)
Query: 112 AICAKPCLNGGVCVRPDQ---CECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTC 168
+I A PC + G CV C+C G+ G C DV+EC + C + G FTC
Sbjct: 396 SIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTC 455
Query: 169 GCPHDLVLGVDGRTC 183
C + G G C
Sbjct: 456 IC----MAGFTGTYC 466
Score = 43.5 bits (101), Expect = 2e-04
Identities = 23/78 (29%), Positives = 32/78 (41%), Gaps = 3/78 (3%)
Query: 96 CCQGWKKRHPGALTCEAICAKPCLNGGVCVR---PDQCECAPGWGGKHCHVDVDECRTSI 152
C QGW+ E PC G+C C C G+ G C D+++C +
Sbjct: 798 CPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNP 857
Query: 153 TLCSHHCFNTAGSFTCGC 170
L C + GSF+C C
Sbjct: 858 CLNGGSCQDGVGSFSCSC 875
Score = 42.7 bits (99), Expect = 4e-04
Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 7/66 (10%)
Query: 118 CLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLG 177
C++G + C CAPG+ G C VDECR+ C + + C CP G
Sbjct: 559 CVDG---IASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPS----G 611
Query: 178 VDGRTC 183
G C
Sbjct: 612 TTGVNC 617
Score = 42.4 bits (98), Expect = 5e-04
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 4/59 (6%)
Query: 115 AKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGC 170
+ PC G C V C C PG+GG HC D+ +C S C + SF+C C
Sbjct: 893 SNPC-GPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLC 950
Score = 42.4 bits (98), Expect = 5e-04
Identities = 31/104 (29%), Positives = 41/104 (39%), Gaps = 29/104 (27%)
Query: 93 HAVCCQGWKKRHPGALTCEAI--------------CA-KPCLNGGVC---VRPDQCECAP 134
H C+G+ G CE + CA +PC +GG C V C C P
Sbjct: 1095 HGGTCRGYM----GGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPP 1150
Query: 135 GWGGKHCHVDVDECRTSITL-----CSHH--CFNTAGSFTCGCP 171
G G C ++ D+C L C H+ C + G F C CP
Sbjct: 1151 GTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCP 1194
Score = 42.0 bits (97), Expect = 6e-04
Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 6/59 (10%)
Query: 118 CLNGGVCVR---PDQCECAPGWGGKHCHVDVDECRTSITLCSH--HCF-NTAGSFTCGC 170
CL+ G CV +C C PG+ G C D++ECR+ +H C + G F C C
Sbjct: 1176 CLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLC 1234
Score = 41.6 bits (96), Expect = 8e-04
Identities = 26/83 (31%), Positives = 32/83 (38%), Gaps = 9/83 (10%)
Query: 114 CAKPCLNGGVCVRPD---QCECAPGWGGKHCHVDV--DECRTSITLCSHHCFNTAGSFTC 168
CA + G+C +C C PGW G C + D C + C + F C
Sbjct: 699 CAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHC 758
Query: 169 GCPHDLVLGVDGRTCMEGSPEPP 191
CP GV GR C SP P
Sbjct: 759 TCPP----GVQGRQCELLSPCTP 777
Score = 41.6 bits (96), Expect = 8e-04
Identities = 20/56 (35%), Positives = 23/56 (41%), Gaps = 3/56 (5%)
Query: 118 CLNGGVCV---RPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGC 170
C NGG CV C C PG+ G HC + D C + L C F C C
Sbjct: 933 CFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTC 988
Score = 41.2 bits (95), Expect = 0.001
Identities = 23/67 (34%), Positives = 29/67 (43%), Gaps = 11/67 (16%)
Query: 116 KPCLNGGVCVRPDQ-CECAPGWGGKHCHVDVDECRTSIT--------LC--SHHCFNTAG 164
+PC NGG CV+ C C PGW G+ C + CR + LC C +
Sbjct: 1007 QPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDS 1066
Query: 165 SFTCGCP 171
S C CP
Sbjct: 1067 SHYCVCP 1073
Score = 39.7 bits (91), Expect = 0.003
Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 3/61 (4%)
Query: 114 CAKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGC 170
CA GVC + C C PG+ G C+V+++EC +S C + F C C
Sbjct: 624 CASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLC 683
Query: 171 P 171
P
Sbjct: 684 P 684
Score = 37.0 bits (84), Expect = 0.021
Identities = 36/120 (30%), Positives = 47/120 (39%), Gaps = 30/120 (25%)
Query: 115 AKPCLNGGVCVRPD---QCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCP 171
++PCL+GGVC +C C + G C VD C C T G++ C CP
Sbjct: 968 SRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT-GAY-CLCP 1025
Query: 172 HDLVLGVDGRTCMEGSPEPPTSASILSVAVREAEKDERALKQEIHELRGRLERLEQWAGQ 231
G GR C I S+ REA ++ RLE+L Q GQ
Sbjct: 1026 P----GWSGRLC-----------DIRSLPCREAAA----------QIGVRLEQLCQAGGQ 1060
Score = 36.2 bits (82), Expect = 0.035
Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 8/51 (15%)
Query: 97 CQGWKKRHPGALTCEAICAKPCLNGGVCVRPD------QCECAPGWGGKHC 141
C+ + PGA A PCL+GG C RP +C CA GW G C
Sbjct: 1324 CRSFPGSPPGASNASCAAA-PCLHGGSC-RPAPLAPFFRCACAQGWTGPRC 1372
Score = 33.9 bits (76), Expect = 0.17
Identities = 14/40 (35%), Positives = 23/40 (57%), Gaps = 3/40 (7%)
Query: 115 AKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTS 151
++PC +GG C V C C G G +C V++D+C ++
Sbjct: 588 SQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASN 627
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 60.8 bits (146), Expect = 1e-09
Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 51 ESYSQPVYKPYLTLCAGRRI---CSTYRTMYRVMWREVRREVQQTHAVCCQGWKKRHPGA 107
ESY P + Y T C C+ +R YR +R + + + + CC G+ +
Sbjct: 46 ESYPHPFDQIYYTSCTDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGF---YESG 102
Query: 108 LTCEAICAKPCLNGGVCVRPDQCECAPGWGGKHC 141
C CA C++G C+ P+ C+C PGWGG +C
Sbjct: 103 EMCVPHCADKCVHGR-CIAPNTCQCEPGWGGTNC 135
Score = 41.2 bits (95), Expect = 0.001
Identities = 25/69 (36%), Positives = 30/69 (43%), Gaps = 14/69 (20%)
Query: 108 LTCEAICAKPCLNGGVCVRPD-QCECAPGWGGKHCHVDVDECRTSITL-----CSH--HC 159
LTC+ CLNGG C D C CAPGW G+ C + + + CSH C
Sbjct: 497 LTCQ------CLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGC 550
Query: 160 FNTAGSFTC 168
T G C
Sbjct: 551 HPTTGHCRC 559
Score = 36.2 bits (82), Expect = 0.035
Identities = 21/51 (41%), Positives = 22/51 (43%), Gaps = 4/51 (7%)
Query: 110 CEAICAKPCLNGGVCVR-PDQCECAPGWGGKHCHVDVDECRTSITLCSHHC 159
CE C PC NGGVC +C C GW G C E R CS C
Sbjct: 234 CEQRC--PCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKN-CSQEC 281
Score = 36.2 bits (82), Expect = 0.035
Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 6/45 (13%)
Query: 118 CLNGGVC-VRPDQCECAPGWGGKHCHVDVDEC--RTSITLCSHHC 159
C NGG C QC C+PG+ G+ C DEC T LC+ C
Sbjct: 283 CHNGGTCDAATGQCHCSPGYTGERCQ---DECPVGTYGVLCAETC 324
Score = 34.3 bits (77), Expect = 0.13
Identities = 33/121 (27%), Positives = 40/121 (33%), Gaps = 40/121 (33%)
Query: 93 HAVCCQGWKKRHPGALTCEAICAKP-----------CLNGGVCVRPDQ-CECAPGWG--- 137
H C GW H C+++CA+ C NG C D CECAPG+
Sbjct: 556 HCRCLPGWSGVH-----CDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTT 610
Query: 138 ----------GKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCMEGS 187
G C +C S C H T C D + G G C E
Sbjct: 611 CQRICSPGFYGHRCSQTCPQCVHSSGPCHH--------ITGLC--DCLPGFTGALCNEVC 660
Query: 188 P 188
P
Sbjct: 661 P 661
Score = 34.3 bits (77), Expect = 0.13
Identities = 20/58 (34%), Positives = 23/58 (39%), Gaps = 4/58 (6%)
Query: 110 CEAICAKPCLNGGVCVRPDQ-CECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSF 166
C IC C N G C D+ C+C PGW G C C H C G+F
Sbjct: 669 CAGICT--CTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPN-CIHTCNCHNGAF 723
Score = 32.3 bits (72), Expect = 0.51
Identities = 12/25 (48%), Positives = 15/25 (60%), Gaps = 1/25 (4%)
Query: 118 CLNGGVCVRPD-QCECAPGWGGKHC 141
C NG C D +C+C PGW G +C
Sbjct: 718 CHNGAFCSAYDGECKCTPGWTGLYC 742
Score = 31.6 bits (70), Expect = 0.87
Identities = 14/33 (42%), Positives = 15/33 (45%), Gaps = 3/33 (9%)
Query: 110 CEAICAKPCLNGGVCVR-PDQCECAPGWGGKHC 141
C IC CLN C C C+PGW G C
Sbjct: 798 CRQIC--DCLNNSTCDHITGTCYCSPGWKGARC 828
Score = 31.2 bits (69), Expect = 1.1
Identities = 22/76 (28%), Positives = 27/76 (35%), Gaps = 8/76 (10%)
Query: 118 CLNGGVCVR-PDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSF------TCGC 170
C NG C +C C PG+ G C D+ C C G C C
Sbjct: 197 CQNGATCDHVTGECRCPPGYTGAFCE-DLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSC 255
Query: 171 PHDLVLGVDGRTCMEG 186
P + V G+ C EG
Sbjct: 256 PSGWMGTVCGQPCPEG 271
Score = 31.2 bits (69), Expect = 1.1
Identities = 30/108 (27%), Positives = 36/108 (33%), Gaps = 32/108 (29%)
Query: 96 CCQGWKKRHPGALTCEAICAKPCLNGGV---------CVRPD-------QCECAPGWGGK 139
C GW+ C PC +G C D C C PGW G
Sbjct: 516 CAPGWRGEK---------CELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGV 566
Query: 140 HCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVL----GVDGRTC 183
HC E R CS C+ G+ +C P D + G G TC
Sbjct: 567 HCDSVCAEGRWGPN-CSLPCYCKNGA-SCS-PDDGICECAPGFRGTTC 611
Score = 29.3 bits (64), Expect = 4.3
Identities = 19/69 (27%), Positives = 24/69 (34%), Gaps = 14/69 (20%)
Query: 129 QCECAPGWGGKHCHVDVD-----ECRTSITLCSH--HCFNTAGSFTCG-------CPHDL 174
+C C PGW G +C+ E I C + C + G TC C
Sbjct: 384 ECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPC 443
Query: 175 VLGVDGRTC 183
LG G C
Sbjct: 444 PLGTYGINC 452
Score = 28.9 bits (63), Expect = 5.6
Identities = 14/33 (42%), Positives = 16/33 (48%), Gaps = 3/33 (9%)
Query: 110 CEAICAKPCLNGGVCVR-PDQCECAPGWGGKHC 141
C IC C NG C QC C G+ G+HC
Sbjct: 755 CALICQ--CQNGADCDHISGQCTCRTGFMGRHC 785
Score = 28.5 bits (62), Expect = 7.3
Identities = 13/37 (35%), Positives = 16/37 (43%), Gaps = 3/37 (8%)
Query: 108 LTCEAICAKPCLNGGVCVRPD-QCECAPGWGGKHCHV 143
+ C + C C N VC D C C GW G C +
Sbjct: 450 INCSSRCG--CKNDAVCSPVDGSCTCKAGWHGVDCSI 484
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 60.5 bits (145), Expect = 2e-09
Identities = 31/85 (36%), Positives = 39/85 (45%), Gaps = 13/85 (15%)
Query: 110 CEAICA----KPCLNGGVCVRPDQ-----CECAPGWGGKHCHVDVDECRTSITLCSHHCF 160
C+ + A PC N VC C CAPGW G+ C +D+DEC + + C
Sbjct: 830 CQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCH 889
Query: 161 NTAGSFTCGCPHDLVLGVDGRTCME 185
NT GS+ C CP G G C E
Sbjct: 890 NTQGSYMCECPP----GFSGMDCEE 910
Score = 57.0 bits (136), Expect = 2e-08
Identities = 35/113 (30%), Positives = 51/113 (45%), Gaps = 20/113 (17%)
Query: 95 VCCQGWKKRHPGALTCEA----ICAKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDE 147
+C GW + CE + PC NGG C V +C C G+ G +C V++DE
Sbjct: 744 LCDAGWV-----GINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDE 798
Query: 148 CRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCM----EGSPEPPTSASI 196
C ++ L CF+ +TC C VL G+ C SP P +A++
Sbjct: 799 CASNPCLNQGTCFDDISGYTCHC----VLPYTGKNCQTVLAPCSPNPCENAAV 847
Score = 53.1 bits (126), Expect = 3e-07
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Query: 95 VCCQGWKKRHPGALTCEAICAKPCLNGGVCVRPD---QCECAPGWGGKHCHVDVDECRTS 151
+C GW+ + + + +KPC+N G+C CEC PG+ G C D+D+C +
Sbjct: 860 LCAPGWQGQRC-TIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLAN 918
Query: 152 ITLCSHHCFNTAGSFTCGC 170
C + +F+C C
Sbjct: 919 PCQNGGSCMDGVNTFSCLC 937
Score = 51.6 bits (122), Expect = 8e-07
Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 7/73 (9%)
Query: 115 AKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCP 171
++PC NGG C V C+C G+ G HC +++EC S C + SF+C CP
Sbjct: 955 SEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCP 1014
Query: 172 HDLVLGVDGRTCM 184
+G G C+
Sbjct: 1015 ----VGFTGSFCL 1023
Score = 51.2 bits (121), Expect = 1e-06
Identities = 29/73 (39%), Positives = 32/73 (43%), Gaps = 9/73 (12%)
Query: 118 CLNGGVCV---RPDQCECAPGWGGKHCHVDVDECRTSITLCSH--HCFNTAGSFTCGCPH 172
C NGGVCV C C P W G+ C DVDEC C + C N G + C C
Sbjct: 269 CQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVC-- 326
Query: 173 DLVLGVDGRTCME 185
V G G C E
Sbjct: 327 --VNGWSGDDCSE 337
Score = 51.2 bits (121), Expect = 1e-06
Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 110 CEAICAKPCLNGGVCVRPD---QCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSF 166
C + PC + G CV D CEC G+ G C +D++EC + C + G F
Sbjct: 419 CAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGF 478
Query: 167 TCGC 170
TC C
Sbjct: 479 TCLC 482
Score = 50.8 bits (120), Expect = 1e-06
Identities = 31/103 (30%), Positives = 44/103 (42%), Gaps = 12/103 (11%)
Query: 95 VCCQGWKKRHPGALTCEAICAKPCLNGGVCV---RPDQCECAPGWGGKHCHVDVDECRTS 151
+C G+K H L + PC+N G CV QC C PG+ G C +D+D+C ++
Sbjct: 481 LCMPGFKGVHC-ELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSST 539
Query: 152 ITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCMEG----SPEP 190
L C + + C C G G C E P+P
Sbjct: 540 PCLNGAKCIDHPNGYECQC----ATGFTGVLCEENIDNCDPDP 578
Score = 49.7 bits (117), Expect = 3e-06
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 7/74 (9%)
Query: 115 AKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCP 171
+ PC +G C + +CEC PG+ G +C +VDEC+ C + F C CP
Sbjct: 1155 SNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCP 1214
Query: 172 HDLVLGVDGRTCME 185
G G C E
Sbjct: 1215 P----GTRGLLCEE 1224
Score = 49.3 bits (116), Expect = 4e-06
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 10/78 (12%)
Query: 111 EAICAKPCLNGGVCV---RPDQCECAPGWGGKHCHVDVDECRTSITLCSH--HCFNTAGS 165
+A + PC NG C C+C G+ G+ C DV+EC C H C N GS
Sbjct: 146 DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIP-GHCQHGGTCLNLPGS 204
Query: 166 FTCGCPHDLVLGVDGRTC 183
+ C CP G G+ C
Sbjct: 205 YQCQCPQ----GFTGQYC 218
Score = 48.9 bits (115), Expect = 5e-06
Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 4/60 (6%)
Query: 115 AKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCP 171
+ PC++G +C + C C+PG+ G+ C++D+DEC ++ C N F C CP
Sbjct: 651 SNPCIHG-ICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICP 709
Score = 48.5 bits (114), Expect = 7e-06
Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 7/72 (9%)
Query: 115 AKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCP 171
A PC NGG C V C C PG+ G C D++EC + C + S+TC C
Sbjct: 917 ANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQ 976
Query: 172 HDLVLGVDGRTC 183
G DG C
Sbjct: 977 ----AGFDGVHC 984
Score = 46.6 bits (109), Expect = 3e-05
Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 118 CLNGGVCVRPDQ---CECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCP 171
C NGG C + C C GW G C ++D+C + C + SF+C CP
Sbjct: 309 CQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCP 365
Score = 46.6 bits (109), Expect = 3e-05
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 7/69 (10%)
Query: 118 CLNGGVCV---RPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDL 174
C NGG CV C C G+ G C +++EC + L C + G++ C CP
Sbjct: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCP--- 1052
Query: 175 VLGVDGRTC 183
LG G+ C
Sbjct: 1053 -LGYTGKNC 1060
Score = 45.8 bits (107), Expect = 4e-05
Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 7/81 (8%)
Query: 96 CCQGWKKRHPGALTCEAICA-KPCLNGGVCVRPD----QCECAPGWGGKHCHVDVDECRT 150
C QG+ ++ +L CA PC+NGG C + +C C PG+ G C ++D+C
Sbjct: 209 CPQGFTGQYCDSLYVP--CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPN 266
Query: 151 SITLCSHHCFNTAGSFTCGCP 171
C + ++ C CP
Sbjct: 267 HRCQNGGVCVDGVNTYNCRCP 287
Score = 45.4 bits (106), Expect = 6e-05
Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 117 PCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCP 171
PC N C + C C PG+ G HC ++++EC+++ + + C + F C CP
Sbjct: 464 PCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCP 521
Score = 43.9 bits (102), Expect = 2e-04
Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 10/73 (13%)
Query: 115 AKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHH-CFNTAGSFTCGC 170
+ PCLN G C V QC C PG G +C ++ D+C ++ C H C + ++C C
Sbjct: 613 SSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASN--PCIHGICMDGINRYSCVC 670
Query: 171 PHDLVLGVDGRTC 183
G G+ C
Sbjct: 671 SP----GFTGQRC 679
Score = 43.9 bits (102), Expect = 2e-04
Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
Query: 116 KPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDEC-RTSITLCSHHCFNTAGSFTCGC 170
+PC NGG C V +C C PG G C ++D+C R L C + G ++C C
Sbjct: 1194 QPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRC 1252
Score = 43.1 bits (100), Expect = 3e-04
Identities = 25/68 (36%), Positives = 31/68 (45%), Gaps = 8/68 (11%)
Query: 111 EAICAKPCLNGGVC-VRPDQ----CECAPGWGGKHCHVDVDEC-RTSITLCSH--HCFNT 162
+A + PC G +C P C C G+ G C DVDEC + C H C NT
Sbjct: 377 DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNT 436
Query: 163 AGSFTCGC 170
G+F C C
Sbjct: 437 DGAFHCEC 444
Score = 43.1 bits (100), Expect = 3e-04
Identities = 34/106 (32%), Positives = 40/106 (37%), Gaps = 24/106 (22%)
Query: 95 VCCQGWKKRHPGALTCEA---ICAK-PCLNGGVCV----RPDQ--CECAPGWGGKHCHVD 144
VC + RH CE +C + PCLNGG C PD C C PG+ G C
Sbjct: 1291 VCRSAFTGRH-----CETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSS 1345
Query: 145 VDE--CRTSITLCSHHCFNTAGSFTCGC--PHDLVLGVDGRTCMEG 186
+ CR C +TA C C P D G C G
Sbjct: 1346 CGQVKCRK-----GEQCVHTASGPRCFCPSPRDCESGCASSPCQHG 1386
Score = 40.8 bits (94), Expect = 0.001
Identities = 24/105 (22%), Positives = 43/105 (40%), Gaps = 16/105 (15%)
Query: 91 QTHAVCCQGWKKRHPGA--LTCEAICAKP-------CLNGGVCVRPDQ---CECAPGWGG 138
++ +C GW + ++C+ ++ C + GVC+ C+C G+ G
Sbjct: 1084 ESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTG 1143
Query: 139 KHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTC 183
+C +DEC ++ C + G + C C V G G C
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCEC----VPGYQGVNC 1184
Score = 40.8 bits (94), Expect = 0.001
Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 9/60 (15%)
Query: 118 CLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHH----CFNTAGSFTCGC 170
CLNGG C + C C PG+ G+ C D++EC ++ CS C + C C
Sbjct: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSN--PCSSEGSLDCIQLTNDYLCVC 1292
Score = 40.4 bits (93), Expect = 0.002
Identities = 23/73 (31%), Positives = 31/73 (42%), Gaps = 9/73 (12%)
Query: 115 AKPCLNGGVCVRPD----QCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGC 170
++PCLNGG C +C C G+ GK C D C + C A F+C C
Sbjct: 112 SRPCLNGGTCHMLSRDTYECTCQVGFTGKECQW-TDACLSHPCANGSTCTTVANQFSCKC 170
Query: 171 PHDLVLGVDGRTC 183
+ G G+ C
Sbjct: 171 ----LTGFTGQKC 179
Score = 39.3 bits (90), Expect = 0.004
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 5/79 (6%)
Query: 95 VCCQGWKKRHPGALTCEAIC-AKPCLNGGVC--VRPDQCECAPGWGGKHCHVDVDECRTS 151
+C +G HP + C + PC++G + +C C GW G +C VD +EC ++
Sbjct: 707 ICPEG--PHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSN 764
Query: 152 ITLCSHHCFNTAGSFTCGC 170
C N + C C
Sbjct: 765 PCQNGGTCDNLVNGYRCTC 783
Score = 37.4 bits (85), Expect = 0.016
Identities = 20/58 (34%), Positives = 24/58 (41%), Gaps = 3/58 (5%)
Query: 117 PCLNGGVCVR---PDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCP 171
PCLN G CV +C C G+ GK+C V+ C S C C CP
Sbjct: 1033 PCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCP 1090
Score = 37.0 bits (84), Expect = 0.021
Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 7/71 (9%)
Query: 105 PGALTCEAICAK-PCLNGGVCVRPDQ-----CECAPGWGGKHCHVDVDECRTSITLC-SH 157
P CE+ CA PC +GG C Q C+CAP + G C + T C S
Sbjct: 1369 PSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQ 1428
Query: 158 HCFNTAGSFTC 168
+C + A C
Sbjct: 1429 YCADKARDGVC 1439
Score = 36.2 bits (82), Expect = 0.035
Identities = 14/41 (34%), Positives = 19/41 (46%)
Query: 130 CECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGC 170
C C PG+ G C +DEC +S L C + + C C
Sbjct: 593 CICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNC 633
Score = 33.9 bits (76), Expect = 0.17
Identities = 34/105 (32%), Positives = 39/105 (37%), Gaps = 21/105 (20%)
Query: 95 VCCQGWKKRHPGALTCEAI--CA-KPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDEC 148
VC GW G E I CA C G C V C C G G CH+D D C
Sbjct: 325 VCVNGWS----GDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLD-DAC 379
Query: 149 RTSI----TLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCMEGSPE 189
++ LC + N G + C CP G G C E E
Sbjct: 380 ISNPCHKGALCDTNPLN--GQYICTCPQ----GYKGADCTEDVDE 418
Score = 32.7 bits (73), Expect = 0.39
Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 11/81 (13%)
Query: 116 KPCLNGGVCVR----PDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTA--GSFTCG 169
+PC+N G+CV C+C G+ G++C D C + C A G TC
Sbjct: 33 EPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATCR 91
Query: 170 CPHDLVLGVDGRTCMEGSPEP 190
C G G C + P
Sbjct: 92 C----ASGFTGEDCQYSTSHP 108
Score = 30.0 bits (66), Expect = 2.5
Identities = 18/57 (31%), Positives = 20/57 (35%), Gaps = 7/57 (12%)
Query: 130 CECAPGWGGKHCHVDVDECRTSITLCSHHC---FNTAGSFTCGCPHDLVLGVDGRTC 183
C C + G+HC VD C L C N F C CP G G C
Sbjct: 1290 CVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPP----GFSGARC 1342
>gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]
Length = 839
Score = 60.5 bits (145), Expect = 2e-09
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
Query: 109 TCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLCSH--HCFNTAGSF 166
TC+A C C NGG C+ + C C G+ G C D+DEC C +C N G +
Sbjct: 543 TCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPGWY 602
Query: 167 TCGC 170
C C
Sbjct: 603 HCEC 606
Score = 34.7 bits (78), Expect = 0.10
Identities = 30/112 (26%), Positives = 46/112 (41%), Gaps = 27/112 (24%)
Query: 88 EVQQTHAVC--CQGW---KKRHPGA-------LTCEAICAKPCLNGGVCVRPDQCECAPG 135
++ +H+ C C+G+ +RH L A+C+ C +G +R D C
Sbjct: 407 QITLSHSCCKVCKGYDFCSERHNCMENSICRNLNDRAVCS--CRDGFRALREDNAYCE-- 462
Query: 136 WGGKHCHVDVDECRTSITLCSHH--CFNTAGSFTCGCPHDLVLGVDGRTCME 185
D+DEC C + C NT GSF C C + +D +C E
Sbjct: 463 --------DIDECAEGRHYCRENTMCVNTPGSFMCICKTGYI-RIDDYSCTE 505
Score = 31.6 bits (70), Expect = 0.87
Identities = 31/120 (25%), Positives = 45/120 (37%), Gaps = 16/120 (13%)
Query: 64 LCAGRRICSTYRTMYRVMWREVRREVQQTHAVCCQ-GWKKRHPGALTCEAI--CAKP--- 117
+C G CS + M + R + C+ G++ CE I CA+
Sbjct: 417 VCKGYDFCSE---RHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHY 473
Query: 118 CLNGGVCVRPD---QCECAPGWG--GKHCHVDVDECRTSITLCSHH--CFNTAGSFTCGC 170
C +CV C C G+ + + DEC T+ C + CFNT G C C
Sbjct: 474 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVC 533
>gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]
Length = 815
Score = 60.5 bits (145), Expect = 2e-09
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
Query: 109 TCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLCSH--HCFNTAGSF 166
TC+A C C NGG C+ + C C G+ G C D+DEC C +C N G +
Sbjct: 519 TCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPGWY 578
Query: 167 TCGC 170
C C
Sbjct: 579 HCEC 582
Score = 34.7 bits (78), Expect = 0.10
Identities = 30/112 (26%), Positives = 46/112 (41%), Gaps = 27/112 (24%)
Query: 88 EVQQTHAVC--CQGW---KKRHPGA-------LTCEAICAKPCLNGGVCVRPDQCECAPG 135
++ +H+ C C+G+ +RH L A+C+ C +G +R D C
Sbjct: 383 QITLSHSCCKVCKGYDFCSERHNCMENSICRNLNDRAVCS--CRDGFRALREDNAYCE-- 438
Query: 136 WGGKHCHVDVDECRTSITLCSHH--CFNTAGSFTCGCPHDLVLGVDGRTCME 185
D+DEC C + C NT GSF C C + +D +C E
Sbjct: 439 --------DIDECAEGRHYCRENTMCVNTPGSFMCICKTGYI-RIDDYSCTE 481
Score = 31.6 bits (70), Expect = 0.87
Identities = 31/120 (25%), Positives = 45/120 (37%), Gaps = 16/120 (13%)
Query: 64 LCAGRRICSTYRTMYRVMWREVRREVQQTHAVCCQ-GWKKRHPGALTCEAI--CAKP--- 117
+C G CS + M + R + C+ G++ CE I CA+
Sbjct: 393 VCKGYDFCSE---RHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHY 449
Query: 118 CLNGGVCVRPD---QCECAPGWG--GKHCHVDVDECRTSITLCSHH--CFNTAGSFTCGC 170
C +CV C C G+ + + DEC T+ C + CFNT G C C
Sbjct: 450 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVC 509
>gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 60.5 bits (145), Expect = 2e-09
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
Query: 109 TCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLCSH--HCFNTAGSF 166
TC+A C C NGG C+ + C C G+ G C D+DEC C +C N G +
Sbjct: 520 TCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPGWY 579
Query: 167 TCGC 170
C C
Sbjct: 580 HCEC 583
Score = 34.7 bits (78), Expect = 0.10
Identities = 30/112 (26%), Positives = 46/112 (41%), Gaps = 27/112 (24%)
Query: 88 EVQQTHAVC--CQGW---KKRHPGA-------LTCEAICAKPCLNGGVCVRPDQCECAPG 135
++ +H+ C C+G+ +RH L A+C+ C +G +R D C
Sbjct: 384 QITLSHSCCKVCKGYDFCSERHNCMENSICRNLNDRAVCS--CRDGFRALREDNAYCE-- 439
Query: 136 WGGKHCHVDVDECRTSITLCSHH--CFNTAGSFTCGCPHDLVLGVDGRTCME 185
D+DEC C + C NT GSF C C + +D +C E
Sbjct: 440 --------DIDECAEGRHYCRENTMCVNTPGSFMCICKTGYI-RIDDYSCTE 482
Score = 31.6 bits (70), Expect = 0.87
Identities = 31/120 (25%), Positives = 45/120 (37%), Gaps = 16/120 (13%)
Query: 64 LCAGRRICSTYRTMYRVMWREVRREVQQTHAVCCQ-GWKKRHPGALTCEAI--CAKP--- 117
+C G CS + M + R + C+ G++ CE I CA+
Sbjct: 394 VCKGYDFCSE---RHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHY 450
Query: 118 CLNGGVCVRPD---QCECAPGWG--GKHCHVDVDECRTSITLCSHH--CFNTAGSFTCGC 170
C +CV C C G+ + + DEC T+ C + CFNT G C C
Sbjct: 451 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVC 510
>gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]
Length = 866
Score = 60.5 bits (145), Expect = 2e-09
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
Query: 109 TCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLCSH--HCFNTAGSF 166
TC+A C C NGG C+ + C C G+ G C D+DEC C +C N G +
Sbjct: 570 TCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPGWY 629
Query: 167 TCGC 170
C C
Sbjct: 630 HCEC 633
Score = 34.7 bits (78), Expect = 0.10
Identities = 30/112 (26%), Positives = 46/112 (41%), Gaps = 27/112 (24%)
Query: 88 EVQQTHAVC--CQGW---KKRHPGA-------LTCEAICAKPCLNGGVCVRPDQCECAPG 135
++ +H+ C C+G+ +RH L A+C+ C +G +R D C
Sbjct: 434 QITLSHSCCKVCKGYDFCSERHNCMENSICRNLNDRAVCS--CRDGFRALREDNAYCE-- 489
Query: 136 WGGKHCHVDVDECRTSITLCSHH--CFNTAGSFTCGCPHDLVLGVDGRTCME 185
D+DEC C + C NT GSF C C + +D +C E
Sbjct: 490 --------DIDECAEGRHYCRENTMCVNTPGSFMCICKTGYI-RIDDYSCTE 532
Score = 31.6 bits (70), Expect = 0.87
Identities = 31/120 (25%), Positives = 45/120 (37%), Gaps = 16/120 (13%)
Query: 64 LCAGRRICSTYRTMYRVMWREVRREVQQTHAVCCQ-GWKKRHPGALTCEAI--CAKP--- 117
+C G CS + M + R + C+ G++ CE I CA+
Sbjct: 444 VCKGYDFCSE---RHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHY 500
Query: 118 CLNGGVCVRPD---QCECAPGWG--GKHCHVDVDECRTSITLCSHH--CFNTAGSFTCGC 170
C +CV C C G+ + + DEC T+ C + CFNT G C C
Sbjct: 501 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVC 560
>gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 60.5 bits (145), Expect = 2e-09
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
Query: 109 TCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITLCSH--HCFNTAGSF 166
TC+A C C NGG C+ + C C G+ G C D+DEC C +C N G +
Sbjct: 520 TCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPGWY 579
Query: 167 TCGC 170
C C
Sbjct: 580 HCEC 583
Score = 34.7 bits (78), Expect = 0.10
Identities = 30/112 (26%), Positives = 46/112 (41%), Gaps = 27/112 (24%)
Query: 88 EVQQTHAVC--CQGW---KKRHPGA-------LTCEAICAKPCLNGGVCVRPDQCECAPG 135
++ +H+ C C+G+ +RH L A+C+ C +G +R D C
Sbjct: 384 QITLSHSCCKVCKGYDFCSERHNCMENSICRNLNDRAVCS--CRDGFRALREDNAYCE-- 439
Query: 136 WGGKHCHVDVDECRTSITLCSHH--CFNTAGSFTCGCPHDLVLGVDGRTCME 185
D+DEC C + C NT GSF C C + +D +C E
Sbjct: 440 --------DIDECAEGRHYCRENTMCVNTPGSFMCICKTGYI-RIDDYSCTE 482
Score = 31.6 bits (70), Expect = 0.87
Identities = 31/120 (25%), Positives = 45/120 (37%), Gaps = 16/120 (13%)
Query: 64 LCAGRRICSTYRTMYRVMWREVRREVQQTHAVCCQ-GWKKRHPGALTCEAI--CAKP--- 117
+C G CS + M + R + C+ G++ CE I CA+
Sbjct: 394 VCKGYDFCSE---RHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHY 450
Query: 118 CLNGGVCVRPD---QCECAPGWG--GKHCHVDVDECRTSITLCSHH--CFNTAGSFTCGC 170
C +CV C C G+ + + DEC T+ C + CFNT G C C
Sbjct: 451 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVC 510
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 60.1 bits (144), Expect = 2e-09
Identities = 36/129 (27%), Positives = 56/129 (43%), Gaps = 19/129 (14%)
Query: 54 SQPVYKPYLTLCAGRRICSTYRTMYRVMWREVRREVQQTHAVCCQGWKKRHPGALTCEAI 113
S+P +P+ G C +YR ++R+V + + CC G+ + C +
Sbjct: 52 SEPCERPW----EGPHTCPQPTVVYRTVYRQVVKTDHRQRLQCCHGFYESRG---FCVPL 104
Query: 114 CAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSI--------TLCSHHCFNTAGS 165
CA+ C++G CV P+QC+C PGW G C EC + C ++ S
Sbjct: 105 CAQECVHGR-CVAPNQCQCVPGWRGDDCS---SECAPGMWGPQCDKPCSCGNNSSCDPKS 160
Query: 166 FTCGCPHDL 174
C CP L
Sbjct: 161 GVCSCPSGL 169
Score = 43.1 bits (100), Expect = 3e-04
Identities = 32/105 (30%), Positives = 41/105 (39%), Gaps = 29/105 (27%)
Query: 96 CCQGWKKRH-----------PGALTCEAICAKPCLNGGVC-VRPDQCECAPGWGGKHCHV 143
C GW H PG C+ C CL+GGVC C+CAPG+ G HC
Sbjct: 382 CLPGWAGLHCNESCPQDTHGPG---CQEHCL--CLHGGVCQATSGLCQCAPGYTGPHC-- 434
Query: 144 DVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLG-VDGR-TCMEG 186
+LC + S C C + + +DG C EG
Sbjct: 435 --------ASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEG 471
Score = 39.7 bits (91), Expect = 0.003
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 21/87 (24%)
Query: 95 VCCQGWKKRH------PGA--LTCEAICAKPCLNGGVCV-RPDQCECAPGWGGKHCHVDV 145
VC +GW++ + PG +C A C C + VC + C C PGW G HC +
Sbjct: 467 VCKEGWQRGNCSVPCPPGTWGFSCNASCQ--CAHEAVCSPQTGACTCTPGWHGAHCQLP- 523
Query: 146 DECRTSITLCSHHCFNTAGSFTCGCPH 172
C F + C C H
Sbjct: 524 ---------CPKGQFGEGCASRCDCDH 541
Score = 37.4 bits (85), Expect = 0.016
Identities = 29/102 (28%), Positives = 39/102 (38%), Gaps = 18/102 (17%)
Query: 93 HAVCCQG-WKKRHPGALTCEAICAKPCLNGGVCVRPD-QCECAPGWGGKHCHVDVDECRT 150
H C +G W + C C C NGG C+ + C CAPG+ G C R
Sbjct: 564 HLSCPEGLW------GVNCSNTCT--CKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRY 615
Query: 151 SITL----CSHHCFNTAGSFTCGCPHDLVLGVDGRTCMEGSP 188
C++H F + TC C + G G C + P
Sbjct: 616 GKRCVPCKCANHSFCHPSNGTCYC----LAGWTGPDCSQPCP 653
Score = 36.6 bits (83), Expect = 0.027
Identities = 33/122 (27%), Positives = 44/122 (36%), Gaps = 20/122 (16%)
Query: 118 CLNGGVCVR-PDQCECAPGWGGKHCHVDV-------DECRTSITLCSHHCFNTAGSFTCG 169
C NGG+C R QC CAPG+ G C + D T CF G+ C
Sbjct: 278 CHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGA--CL 335
Query: 170 CPHDLVLGVDGRTCMEG-SPEPPTSASILSVAVREAEKDERALKQEIHELRGRLERLEQW 228
C H G G C + P+ ++ + +R H + G L W
Sbjct: 336 CEH----GFTGDRCTDRLCPD-----GFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGW 386
Query: 229 AG 230
AG
Sbjct: 387 AG 388
Score = 34.3 bits (77), Expect = 0.13
Identities = 21/76 (27%), Positives = 27/76 (35%), Gaps = 18/76 (23%)
Query: 96 CCQGWKKRHPGALTCEAICAKPCLNGGVCVRPD------------QCECAPGWGGKHCHV 143
C GW H C+ C K G R D +C+C GW G CH+
Sbjct: 511 CTPGWHGAH-----CQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHL 565
Query: 144 DVDECRTSITLCSHHC 159
E + CS+ C
Sbjct: 566 SCPEGLWGVN-CSNTC 580
Score = 33.9 bits (76), Expect = 0.17
Identities = 35/112 (31%), Positives = 39/112 (34%), Gaps = 15/112 (13%)
Query: 96 CCQGWKKRHPGALTCEAICAKPCLNGGVCVRPD-QCECAPGWGGKHCHVDVDECRTSITL 154
C Q H G C C C +GG C D C C GW G HC ++ T
Sbjct: 648 CSQPCPPGHWGE-NCAQTCQ--CHHGGTCHPQDGSCICPLGWTGHHC-LEGCPLGTFGAN 703
Query: 155 CSHHCFNTAG------SFTCGCPHDLVLGVDGRTCMEGSPEPPTSASILSVA 200
CS C G + C CP G G C G EP T VA
Sbjct: 704 CSQPCQCGPGEKCHPETGACVCPP----GHSGAPCRIGIQEPFTVMPTTPVA 751
Score = 32.3 bits (72), Expect = 0.51
Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 2/53 (3%)
Query: 108 LTCEAICAKPCLNGGVCVRPD-QCECAPGWGGKHCHVDVDECRTSITLCSHHC 159
L+C+A C + C + +C C PGW G HC+ + T C HC
Sbjct: 357 LSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQ-DTHGPGCQEHC 408
Score = 31.6 bits (70), Expect = 0.87
Identities = 14/31 (45%), Positives = 15/31 (48%), Gaps = 1/31 (3%)
Query: 118 CLNGGVCVRPD-QCECAPGWGGKHCHVDVDE 147
C NGGV P C C PGW G C + E
Sbjct: 235 CQNGGVFQTPQGSCSCPPGWMGTICSLPCPE 265
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 60.1 bits (144), Expect = 2e-09
Identities = 25/62 (40%), Positives = 34/62 (54%), Gaps = 3/62 (4%)
Query: 115 AKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCP 171
+ PC NG VC + C C PG+ G+HC ++VDEC + C N G +TC CP
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICP 213
Query: 172 HD 173
H+
Sbjct: 214 HN 215
Score = 50.8 bits (120), Expect = 1e-06
Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 115 AKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCP 171
++PCLNG C + C+CAPG+ G HC ++ DEC + L C + ++C C
Sbjct: 230 SQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCT 289
Query: 172 HDLVLGVDGRTCM 184
G T M
Sbjct: 290 GSGFTGTHCETLM 302
Score = 50.8 bits (120), Expect = 1e-06
Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 106 GALTCEAICAKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSH-HCFN 161
G L + PCL+GG C C C GW GKHC +++DEC ++ C H +C +
Sbjct: 1136 GCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN--PCIHGNCSD 1193
Query: 162 TAGSFTCGC 170
++ C C
Sbjct: 1194 RVAAYHCTC 1202
Score = 49.3 bits (116), Expect = 4e-06
Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Query: 93 HAVCCQGWKKRHPGALTCEAICAKPCLNGGVC--VRPDQCECAPGWGGKHCHVDVDECRT 150
H C GW +H L + + PC++G V C C PG+ G +C VD+D C++
Sbjct: 1162 HCSCPLGWSGKHC-ELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQS 1220
Query: 151 SITLCSHHCFNTAGSFTCGC 170
C + ++C C
Sbjct: 1221 HQCANGATCISHTNGYSCLC 1240
Score = 47.0 bits (110), Expect = 2e-05
Identities = 19/44 (43%), Positives = 25/44 (56%)
Query: 130 CECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHD 173
C C PG+ G HC DV+EC ++ C N G++TC CP D
Sbjct: 383 CICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFD 426
Score = 42.4 bits (98), Expect = 5e-04
Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Query: 96 CCQGWKKRHPGALTCEAICAKPCLNGGVCVRPD---QCECAPGWGGKHCHVDVDECRTSI 152
C G++ RH L + + PC N C+ C C + G +C +++DEC +
Sbjct: 174 CVPGYQGRHCD-LEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQP 232
Query: 153 TLCSHHCFNTAGSFTCGC 170
L C + G++ C C
Sbjct: 233 CLNGATCQDALGAYFCDC 250
Score = 42.0 bits (97), Expect = 6e-04
Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 8/74 (10%)
Query: 114 CAK-PCLNGGVCVRPD---QCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCG 169
C K C +GG+C + C C G+ G+ C +D DEC +S C + ++C
Sbjct: 114 CGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCF 173
Query: 170 CPHDLVLGVDGRTC 183
C V G GR C
Sbjct: 174 C----VPGYQGRHC 183
Score = 41.6 bits (96), Expect = 8e-04
Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 118 CLNGGVCVRPD---QCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGC 170
C NGG C +C C PG+ G+ C D+DEC + + C + F C C
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLC 1323
Score = 38.5 bits (88), Expect = 0.007
Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 5/79 (6%)
Query: 96 CCQGWKKRHPGALTCEAICAKPCLNGGVCVRPD---QCEC-APGWGGKHCHVDVDECRTS 151
C G+ H L + ++PCL+GG+CV + C C G+ G HC + C +
Sbjct: 250 CAPGFLGDHC-ELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSK 308
Query: 152 ITLCSHHCFNTAGSFTCGC 170
+ C ++ ++TC C
Sbjct: 309 PCHNNATCEDSVDNYTCHC 327
Score = 37.7 bits (86), Expect = 0.012
Identities = 16/48 (33%), Positives = 24/48 (50%), Gaps = 3/48 (6%)
Query: 115 AKPCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHC 159
+KPC N C V C C PG+ G C +D++EC ++ + C
Sbjct: 307 SKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGEC 354
Score = 34.3 bits (77), Expect = 0.13
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 10/69 (14%)
Query: 114 CAK-PCLNGGVC---VRPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCG 169
CA PC+NGG+C + QC C + G+ C VD+ + S F T GS T
Sbjct: 1301 CASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLIS------DIFTTIGSVTVA 1354
Query: 170 CPHDLVLGV 178
L+L +
Sbjct: 1355 LLLILLLAI 1363
Score = 32.3 bits (72), Expect = 0.51
Identities = 20/74 (27%), Positives = 25/74 (33%), Gaps = 9/74 (12%)
Query: 115 AKPCLNGGVCV-----RPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCG 169
+ PC CV R C+C PG+ G C + C + C C
Sbjct: 76 SNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCI 135
Query: 170 CPHDLVLGVDGRTC 183
CP G GR C
Sbjct: 136 CP----AGYAGRFC 145
>gi|4506121 protein Z, vitamin K-dependent plasma glycoprotein [Homo
sapiens]
Length = 400
Score = 59.7 bits (143), Expect = 3e-09
Identities = 34/105 (32%), Positives = 50/105 (47%), Gaps = 8/105 (7%)
Query: 84 EVRREVQQTHAVCCQGWKKRHPGALTCEAICAKPCLNGGVC---VRPDQCECAPGWGGKH 140
E REV + V + W+ R+ G C ++PCL+ G C + C C+PG+ G +
Sbjct: 66 EEAREVFENEVVTDEFWR-RYKGGSPC---ISQPCLHNGSCQDSIWGYTCTCSPGYEGSN 121
Query: 141 CHVDVDECRTSITL-CSHHCFNTAGSFTCGCPHDLVLGVDGRTCM 184
C + +EC T C H C S+TC C LG D + C+
Sbjct: 122 CELAKNECHPERTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCV 166
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 59.3 bits (142), Expect = 4e-09
Identities = 37/104 (35%), Positives = 54/104 (51%), Gaps = 14/104 (13%)
Query: 93 HAVCCQGWKKRHPGALTCEAI--CA--KPCLNGGVCVRPD---QCECAPGW----GGKHC 141
H VC G+ G CE + C+ CLNG +C+ D +C C PG+ G++C
Sbjct: 554 HCVCNAGFHVTRDGK-NCEDMDECSIRNMCLNG-MCINEDGSFKCICKPGFQLASDGRYC 611
Query: 142 HVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCME 185
D++EC T + C NT GS+ C C L +G+DGR C++
Sbjct: 612 K-DINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVD 654
Score = 48.5 bits (114), Expect = 7e-06
Identities = 28/81 (34%), Positives = 37/81 (45%), Gaps = 4/81 (4%)
Query: 109 TCEAICAKPCLNGGV--CVRPDQCECAPGW--GGKHCHVDVDECRTSITLCSHHCFNTAG 164
T E PC NG + +C C G+ G D++EC + LC+ C NT G
Sbjct: 2167 TDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYG 2226
Query: 165 SFTCGCPHDLVLGVDGRTCME 185
S+ C CP VL D R C +
Sbjct: 2227 SYECKCPVGYVLREDRRMCKD 2247
Score = 47.8 bits (112), Expect = 1e-05
Identities = 32/83 (38%), Positives = 38/83 (45%), Gaps = 11/83 (13%)
Query: 110 CEAICAKPCLNGGVCVRPD---QCECAPGW--GGKHCHVDVDECRTSITLCSHH--CFNT 162
CE I A C VC +C C+PGW G C D+DEC +CS H C NT
Sbjct: 1326 CE-IGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKC-TDLDECSNGTHMCSQHADCKNT 1383
Query: 163 AGSFTCGCPHDLVLGVDGRTCME 185
GS+ C C DG TC +
Sbjct: 1384 MGSYRCLCKEGYT--GDGFTCTD 1404
Score = 47.8 bits (112), Expect = 1e-05
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 9/75 (12%)
Query: 118 CLNGGVCVRPD---QCECAPGWG----GKHCHVDVDECRTSITLCSHHCFNTAGSFTCGC 170
C NG CV C C G+ G C VD++EC + C+ C NT GS+ C C
Sbjct: 2413 CRNGE-CVNDRGSYHCICKTGYTPDITGTSC-VDLNECNQAPKPCNFICKNTEGSYQCSC 2470
Query: 171 PHDLVLGVDGRTCME 185
P +L DGR+C +
Sbjct: 2471 PKGYILQEDGRSCKD 2485
Score = 47.0 bits (110), Expect = 2e-05
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 8/101 (7%)
Query: 93 HAVCCQGWKKRHPGALTCEAI-CAKPCLNGGVC---VRPDQCECAPGWGGKHCH--VDVD 146
+ +C G+K + + C + G C + C C G+ H + +DVD
Sbjct: 1873 YCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVD 1932
Query: 147 ECRTSI-TLCSH-HCFNTAGSFTCGCPHDLVLGVDGRTCME 185
EC + LC + C NT GSF C C + DGRTC++
Sbjct: 1933 ECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVD 1973
Score = 46.6 bits (109), Expect = 3e-05
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 4/52 (7%)
Query: 93 HAVCCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVD 144
H +C +G+ H G + +C CLNGG CV P++C C G+ G C D
Sbjct: 133 HCLCQKGYIGTHCG----QPVCESGCLNGGRCVAPNRCACTYGFTGPQCERD 180
Score = 46.6 bits (109), Expect = 3e-05
Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 28/101 (27%)
Query: 124 CVRPDQCECAPGWGGKHCH-----------------------VDVDECRTSITLCSHHCF 160
CV ++C A GG CH D++EC ++ CS+ C
Sbjct: 2605 CVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCS 2664
Query: 161 NTAGSFTCGCPHDLV-LG----VDGRTCMEGSPEPPTSASI 196
NT G + CGCP +G V G G+PEPP S +
Sbjct: 2665 NTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGNPEPPVSGEM 2705
Score = 46.2 bits (108), Expect = 3e-05
Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 3/57 (5%)
Query: 130 CECAPGWGGKHCH-VDVDECRTSITLCSHH--CFNTAGSFTCGCPHDLVLGVDGRTC 183
C+C PG+ H +D +EC + I LC C NT GSFTC C L G +C
Sbjct: 2509 CKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSC 2565
Score = 45.8 bits (107), Expect = 4e-05
Identities = 31/98 (31%), Positives = 43/98 (43%), Gaps = 9/98 (9%)
Query: 94 AVCCQGWKKRHPGALTCEAICAKPCLNGGVCVR---PDQCECAPGWG----GKHCHVDVD 146
A+C G G+ E G+C +C C G+ GK+C VD++
Sbjct: 709 ALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNC-VDIN 767
Query: 147 ECRTSITLCSH-HCFNTAGSFTCGCPHDLVLGVDGRTC 183
EC + LC + C NT GSF C CP + D +TC
Sbjct: 768 ECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTC 805
Score = 45.4 bits (106), Expect = 6e-05
Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 122 GVCVRPD---QCECAPGWG--GKHCHVDVDECRTSITLCS-HHCFNTAGSFTCGCPHDLV 175
G C D +C C PG+ + C D+DEC +C+ C NT GSF C CP
Sbjct: 1987 GTCQNLDGSYRCICPPGYSLQNEKCE-DIDECVEEPEICALGTCSNTEGSFKCLCPEGFS 2045
Query: 176 LGVDGRTCME 185
L GR C +
Sbjct: 2046 LSSSGRRCQD 2055
Score = 45.1 bits (105), Expect = 8e-05
Identities = 30/91 (32%), Positives = 39/91 (42%), Gaps = 16/91 (17%)
Query: 93 HAVCCQGWKKRHPGALTCEAI-----CAKPCLNGGVCVRPD---QCECAPGW----GGKH 140
H +C G+ G +C + KPC +C + QC C G+ G+
Sbjct: 2426 HCICKTGYTPDITGT-SCVDLNECNQAPKPC--NFICKNTEGSYQCSCPKGYILQEDGRS 2482
Query: 141 CHVDVDECRTSITLCSHHCFNTAGSFTCGCP 171
C D+DEC T C C NT G FTC CP
Sbjct: 2483 CK-DLDECATKQHNCQFLCVNTIGGFTCKCP 2512
Score = 44.7 bits (104), Expect = 1e-04
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 5/58 (8%)
Query: 132 CAPGWG---GKHCHVDVDECRTSITLCSHH-CFNTAGSFTCGCPHDLVLGVDGRTCME 185
C G+ G C D+DEC +C + C NT GSF C CP + L GR C++
Sbjct: 896 CGKGYSRIKGTQCE-DIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLD 952
Score = 44.7 bits (104), Expect = 1e-04
Identities = 34/123 (27%), Positives = 47/123 (38%), Gaps = 26/123 (21%)
Query: 88 EVQQTHAVCCQGWKKRHPGALTCE-------AICAKPCLNGGVCVRPD------------ 128
E + +C G PG CE + K C + C P+
Sbjct: 1407 ECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPG 1466
Query: 129 --QCECAPGW----GGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRT 182
+CEC G+ G +C DV+EC T S +C NT GS+ C CP D L
Sbjct: 1467 LFRCECEIGYELDRSGGNC-TDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVG 1525
Query: 183 CME 185
C++
Sbjct: 1526 CVD 1528
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 14/106 (13%)
Query: 93 HAVCCQGWKKRHPGALTCEAICAKPC------LNGGVCVRPD---QCECAPGW----GGK 139
+ + C G + P +T C GG C+ QC C G+ +
Sbjct: 1585 YKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTR 1644
Query: 140 HCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCME 185
C DV+EC T C+NT G++TC CP D + G CM+
Sbjct: 1645 VCD-DVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMD 1689
Score = 43.5 bits (101), Expect = 2e-04
Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 16/91 (17%)
Query: 108 LTCEAICAKPCLNGGVCVRPDQC---------ECAPGW---GGKHCHVDVDECRTSITLC 155
L CE I C NG VC R +C +C PG+ C+ D +EC+ +C
Sbjct: 1804 LVCEDI--DECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCN-DRNECQEIPNIC 1860
Query: 156 SH-HCFNTAGSFTCGCPHDLVLGVDGRTCME 185
SH C +T GSF C C D C++
Sbjct: 1861 SHGQCIDTVGSFYCLCHTGFKTNDDQTMCLD 1891
Score = 43.1 bits (100), Expect = 3e-04
Identities = 29/82 (35%), Positives = 36/82 (43%), Gaps = 8/82 (9%)
Query: 110 CEAICAKPCLNGGVCVR---PDQCECAPGWGGKHCH---VDVDECRTSITLCSHHCFNTA 163
CE + A C NG CV QC C PG+ VD+DEC C C N+
Sbjct: 1159 CE-LSAHLCPNGR-CVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSE 1216
Query: 164 GSFTCGCPHDLVLGVDGRTCME 185
GS+ C C L D R+C +
Sbjct: 1217 GSYECSCQPGFALMPDQRSCTD 1238
Score = 42.4 bits (98), Expect = 5e-04
Identities = 37/133 (27%), Positives = 46/133 (34%), Gaps = 40/133 (30%)
Query: 92 THAVCCQ--GWKKRHPGALTCEAICAKP--CLNG-------GVCVRPDQCECAPGW---- 136
T +CC G HP CE A+P C G G C D+C+ PG
Sbjct: 205 TKTLCCATVGRAWGHP----CEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGG 260
Query: 137 ------GGKHCHV--------------DVDECRTSITLCSH-HCFNTAGSFTCGCPHDLV 175
G C D+DEC T +C C NT S+ C CP
Sbjct: 261 NCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFY 320
Query: 176 LGVDGRTCMEGSP 188
DG C++ P
Sbjct: 321 TSPDGTRCIDVRP 333
Score = 42.4 bits (98), Expect = 5e-04
Identities = 35/128 (27%), Positives = 48/128 (37%), Gaps = 23/128 (17%)
Query: 79 RVMWREVRREVQQTHAVCCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGWGG 138
RV+ V Q +C G PG+ CE G C+ D+CE P GG
Sbjct: 443 RVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGG 502
Query: 139 K----------HCHV------------DVDECRTSITLCSH-HCFNTAGSFTCGCPHDLV 175
+ C D+DEC + +C++ C NT GSF C C
Sbjct: 503 ECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFH 562
Query: 176 LGVDGRTC 183
+ DG+ C
Sbjct: 563 VTRDGKNC 570
Score = 42.0 bits (97), Expect = 6e-04
Identities = 26/86 (30%), Positives = 32/86 (37%), Gaps = 12/86 (13%)
Query: 93 HAVCCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCEC-----APGWGGK---HCHVD 144
+A CC GWK G IC C G C RP+ C C AP G + HC++
Sbjct: 64 NAYCCPGWKTLPGGNQCIVPICRHSC-GDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNI- 121
Query: 145 VDECRTSITLCSHHCFNTAGSFTCGC 170
C + HC G C
Sbjct: 122 --RCMNGGSCSDDHCLCQKGYIGTHC 145
Score = 41.6 bits (96), Expect = 8e-04
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 7/63 (11%)
Query: 130 CECAPGWG------GKHCHVDVDECRTSITLCSH-HCFNTAGSFTCGCPHDLVLGVDGRT 182
C PG+ GK D++EC+ +LC+H C NT GSF C C L + R
Sbjct: 1008 CPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERN 1067
Query: 183 CME 185
C +
Sbjct: 1068 CTD 1070
Score = 41.6 bits (96), Expect = 8e-04
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Query: 129 QCECAPGWGGK-HCHVDVDECRTSITLCSH-HCFNTAGSFTCGCPHDLVLGVDGRTC 183
+C C G+ G D+DEC ++ LC + C N G + C C V DG+ C
Sbjct: 1388 RCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKAC 1444
Score = 41.2 bits (95), Expect = 0.001
Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 6/61 (9%)
Query: 130 CECAPGW----GGKHCHVDVDECRTSITLCSH-HCFNTAGSFTCGCPHDLVLGVDGRTCM 184
C C PG+ G+ C VD +EC+T +C + C NT GS+TC C + C+
Sbjct: 2274 CICGPGYQRRPDGEGC-VDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECL 2332
Query: 185 E 185
+
Sbjct: 2333 D 2333
Score = 40.8 bits (94), Expect = 0.001
Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 10/91 (10%)
Query: 105 PGALTCEAICAKPCLNGGV---CVRPD---QCECAPGWG---GKHCHVDVDECRTSITLC 155
P L C I +NGG C + +C C PG+ + D+DEC + +C
Sbjct: 1190 PDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNIC 1249
Query: 156 SH-HCFNTAGSFTCGCPHDLVLGVDGRTCME 185
C N G + C C + D +TC++
Sbjct: 1250 DGGQCTNIPGEYRCLCYDGFMASEDMKTCVD 1280
Score = 39.7 bits (91), Expect = 0.003
Identities = 21/51 (41%), Positives = 27/51 (52%), Gaps = 6/51 (11%)
Query: 143 VDVDECRTSITLCSH-HCFNTAGSFTCGCPHDLVLG----VDGRTCMEGSP 188
VD+DEC+ +C H C NT GS+ C CP +L VD C G+P
Sbjct: 2126 VDMDECKEP-DVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVGNP 2175
Score = 39.7 bits (91), Expect = 0.003
Identities = 23/75 (30%), Positives = 31/75 (41%), Gaps = 9/75 (12%)
Query: 118 CLNGGVCVRPD---QCECAPGWG----GKHCHVDVDECRTSITLCSHHCFNTAGSFTCGC 170
C + G+C CEC G+ G C DVDEC + C H C N G + C C
Sbjct: 2535 CGSKGICQNTPGSFTCECQRGFSLDQTGSSCE-DVDECEGNHR-CQHGCQNIIGGYRCSC 2592
Query: 171 PHDLVLGVDGRTCME 185
P + C++
Sbjct: 2593 PQGYLQHYQWNQCVD 2607
Score = 38.9 bits (89), Expect = 0.005
Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 10/73 (13%)
Query: 122 GVCVRPD---QCECAPGWGG-----KHCHVDVDECRTSITLCSHH-CFNTAGSFTCGCPH 172
G CV +C+C G+ K+C +D+DEC+ LC C NT GS+ C CP
Sbjct: 1084 GQCVNTPGDFECKCDEGYESGFMMMKNC-MDIDECQRDPLLCRGGVCHNTEGSYRCECPP 1142
Query: 173 DLVLGVDGRTCME 185
L + C++
Sbjct: 1143 GHQLSPNISACID 1155
Score = 38.9 bits (89), Expect = 0.005
Identities = 19/46 (41%), Positives = 22/46 (47%), Gaps = 5/46 (10%)
Query: 130 CECAPGWGGKHCHV---DVDECRTSITLCSHH--CFNTAGSFTCGC 170
C C G+ GK D++EC C H C NTAGSF C C
Sbjct: 1305 CHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSC 1350
Score = 37.4 bits (85), Expect = 0.016
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 6/47 (12%)
Query: 129 QCECAPGWG----GKHCHVDVDECRTSITLCSH-HCFNTAGSFTCGC 170
+C C G+ ++C D+DECR S LC C NT G F C C
Sbjct: 1052 KCRCDSGFALDSEERNC-TDIDECRISPDLCGRGQCVNTPGDFECKC 1097
Score = 35.8 bits (81), Expect = 0.046
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 18/91 (19%)
Query: 95 VCCQGWKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGWGGKHCHVDVDECRTSITL 154
+C G + PG+ C C K G +PD C D+DEC +S +
Sbjct: 775 LCDNGQCRNTPGSFVCT--CPK-----GFIYKPDLKTCE----------DIDECESSPCI 817
Query: 155 CSHHCFNTAGSFTCGCPHDLVLGVDGRTCME 185
+ C N+ GSF C C + L C+E
Sbjct: 818 -NGVCKNSPGSFICECSSESTLDPTKTICIE 847
Score = 35.4 bits (80), Expect = 0.060
Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 6/54 (11%)
Query: 122 GVCVRPD---QCECAPGW--GGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGC 170
G C+ D +CEC G+ G C VD DEC + C N G F C C
Sbjct: 2140 GQCINTDGSYRCECPFGYILAGNEC-VDTDECSVGNPCGNGTCKNVIGGFECTC 2192
Score = 35.0 bits (79), Expect = 0.078
Identities = 15/30 (50%), Positives = 18/30 (60%), Gaps = 1/30 (3%)
Query: 143 VDVDECRTSITLCSHH-CFNTAGSFTCGCP 171
VD+DECR +C + C N GSF C CP
Sbjct: 1765 VDIDECREIPGVCENGVCINMVGSFRCECP 1794
Score = 33.5 bits (75), Expect = 0.23
Identities = 21/58 (36%), Positives = 29/58 (50%), Gaps = 11/58 (18%)
Query: 122 GVCVR---PDQCECAPGWGGKH----CHVDVDECRTSITLCSHH--CFNTAGSFTCGC 170
GVC+ +CEC G+ C D+DEC+ +C + C NTAGS+ C C
Sbjct: 1780 GVCINMVGSFRCECPVGFFYNDKLLVCE-DIDECQNG-PVCQRNAECINTAGSYRCDC 1835
Score = 33.1 bits (74), Expect = 0.30
Identities = 23/59 (38%), Positives = 29/59 (49%), Gaps = 9/59 (15%)
Query: 120 NGGVCVRPD---QCECAPGWGG----KHCHVDVDECRTSITLC-SHHCFNTAGSFTCGC 170
+GG C +C C G+ K C VDV+EC + +C S C NT GSF C C
Sbjct: 1250 DGGQCTNIPGEYRCLCYDGFMASEDMKTC-VDVNECDLNPNICLSGTCENTKGSFICHC 1307
Score = 30.8 bits (68), Expect = 1.5
Identities = 15/58 (25%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 129 QCECAPGWGGKHCHVDVDECRTSITLCSHH-CFNTAGSFTCGCPHDLVLGVDGRTCME 185
Q C+ G G D++EC +C + C N G++ C C + G+ C++
Sbjct: 708 QALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVD 765
Score = 29.6 bits (65), Expect = 3.3
Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 16/103 (15%)
Query: 96 CCQGWKKRHPGAL-TCEAI--CAK-PCLNGGVCVRPD---QCECAPGW---GGKHCHVDV 145
C +G++ PG + TCE I CA+ P L CV +C+C G+ + D
Sbjct: 2192 CEEGFE---PGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDE 2248
Query: 146 DECRTSITLCSH---HCFNTAGSFTCGCPHDLVLGVDGRTCME 185
DEC C+ C N G++ C C DG C++
Sbjct: 2249 DECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVD 2291
>gi|153792110 HEG homolog 1 [Homo sapiens]
Length = 1381
Score = 58.5 bits (140), Expect = 7e-09
Identities = 29/64 (45%), Positives = 34/64 (53%), Gaps = 6/64 (9%)
Query: 114 CA-KPCLNGGVCV-----RPDQCECAPGWGGKHCHVDVDECRTSITLCSHHCFNTAGSFT 167
CA PCL+ G CV R C C P W G C VDV+EC ++ + C NT GSF
Sbjct: 989 CAVNPCLHNGECVADNTSRGYHCRCPPSWQGDDCSVDVNECLSNPCPSTAMCNNTQGSFI 1048
Query: 168 CGCP 171
C CP
Sbjct: 1049 CKCP 1052
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.452
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,762,353
Number of Sequences: 37866
Number of extensions: 692415
Number of successful extensions: 4172
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 187
Number of HSP's successfully gapped in prelim test: 135
Number of HSP's that attempted gapping in prelim test: 2581
Number of HSP's gapped (non-prelim): 1320
length of query: 293
length of database: 18,247,518
effective HSP length: 101
effective length of query: 192
effective length of database: 14,423,052
effective search space: 2769225984
effective search space used: 2769225984
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.