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Search of human proteins with 58865339
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58865339 defensin, beta 121 [Homo sapiens]
(76 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58865339 defensin, beta 121 [Homo sapiens] 158 8e-40
gi|23503331 defensin, beta 123 precursor [Homo sapiens] 67 4e-12
gi|16905373 beta-defensin 118 [Homo sapiens] 54 3e-08
gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens] 52 1e-07
gi|116517226 beta-defensin 135 [Homo sapiens] 50 3e-07
gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens] 45 1e-05
gi|46409558 beta-defensin 32 precursor [Homo sapiens] 44 4e-05
gi|76563936 defensin, beta 125 preproprotein [Homo sapiens] 43 6e-05
gi|83582798 beta-defensin 115 [Homo sapiens] 42 8e-05
gi|82734223 beta-defensin 124 [Homo sapiens] 40 3e-04
gi|83582800 beta-defensin 116 [Homo sapiens] 40 3e-04
gi|13624333 defensin, beta 126 preproprotein [Homo sapiens] 38 0.002
gi|21040279 defensin, beta 127 preproprotein [Homo sapiens] 37 0.003
gi|169166494 PREDICTED: hypothetical protein [Homo sapiens] 35 0.017
gi|50344744 beta-defensin 108B [Homo sapiens] 35 0.017
gi|83582802 beta-defensin 128 [Homo sapiens] 35 0.017
gi|18250304 beta defensin 129 precursor [Homo sapiens] 35 0.017
gi|103485139 defensin, beta 104A precursor [Homo sapiens] 34 0.022
gi|103485137 defensin, beta 104B precursor [Homo sapiens] 34 0.022
gi|239753808 PREDICTED: hypothetical protein [Homo sapiens] 33 0.050
gi|239748372 PREDICTED: hypothetical protein [Homo sapiens] 33 0.050
gi|74136827 beta-defensin 134 [Homo sapiens] 33 0.050
gi|22748611 defensin, beta 106A precursor [Homo sapiens] 31 0.19
gi|103485143 defensin, beta 106B precursor [Homo sapiens] 31 0.19
gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens] 31 0.25
gi|239751980 PREDICTED: defensin, beta 117 [Homo sapiens] 31 0.25
gi|239746467 PREDICTED: defensin, beta 117 [Homo sapiens] 31 0.25
gi|239744548 PREDICTED: hypothetical protein XP_002343194 [Homo ... 30 0.32
gi|82734219 beta-defensin 114 [Homo sapiens] 30 0.32
gi|4506105 prolactin precursor [Homo sapiens] 29 0.72
>gi|58865339 defensin, beta 121 [Homo sapiens]
Length = 76
Score = 158 bits (400), Expect = 8e-40
Identities = 76/76 (100%), Positives = 76/76 (100%)
Query: 1 MKLLLLLLTVTLLLAQVTPVMKCWGKSGRCRTTCKESEVYYILCKTEAKCCVDPKYVPVK 60
MKLLLLLLTVTLLLAQVTPVMKCWGKSGRCRTTCKESEVYYILCKTEAKCCVDPKYVPVK
Sbjct: 1 MKLLLLLLTVTLLLAQVTPVMKCWGKSGRCRTTCKESEVYYILCKTEAKCCVDPKYVPVK 60
Query: 61 PKLTDTNTSLESTSAV 76
PKLTDTNTSLESTSAV
Sbjct: 61 PKLTDTNTSLESTSAV 76
>gi|23503331 defensin, beta 123 precursor [Homo sapiens]
Length = 67
Score = 66.6 bits (161), Expect = 4e-12
Identities = 31/60 (51%), Positives = 37/60 (61%), Gaps = 2/60 (3%)
Query: 1 MKLLLLLLTVTLLLAQVTP--VMKCWGKSGRCRTTCKESEVYYILCKTEAKCCVDPKYVP 58
MKLLLL LTV LLL+Q+TP +CW G+CR C + E Y+ C CCV PKY P
Sbjct: 1 MKLLLLTLTVLLLLSQLTPGGTQRCWNLYGKCRYRCSKKERVYVYCINNKMCCVKPKYQP 60
>gi|16905373 beta-defensin 118 [Homo sapiens]
Length = 123
Score = 53.9 bits (128), Expect = 3e-08
Identities = 26/56 (46%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Query: 1 MKLLLLLLTVTLLLAQVTPVM----KCWGKSGRCRTTCKESEVYYILCKTEAKCCV 52
MKLLLL L + +LL QV P KCW +SG CR CK+ E CK CC+
Sbjct: 1 MKLLLLALPMLVLLPQVIPAYSGEKKCWNRSGHCRKQCKDGEAVKDTCKNLRACCI 56
>gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens]
Length = 88
Score = 51.6 bits (122), Expect = 1e-07
Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Query: 1 MKLLLLLLTVTLLLAQVTPVMKCWGKSGRCRTTCKESEVYYILCKTEAKCCVDPKYVPVK 60
MKLL L L + L + + ++CW G CR CK+ E I C+ +CCV +Y+ ++
Sbjct: 1 MKLLYLFLAILLAIEEPVISVECW-MDGHCRLLCKDGEDSIIRCRNRKRCCVPSRYLTIQ 59
Query: 61 P 61
P
Sbjct: 60 P 60
>gi|116517226 beta-defensin 135 [Homo sapiens]
Length = 77
Score = 50.4 bits (119), Expect = 3e-07
Identities = 27/68 (39%), Positives = 33/68 (48%), Gaps = 12/68 (17%)
Query: 4 LLLLLTVTLLLAQVTP------------VMKCWGKSGRCRTTCKESEVYYILCKTEAKCC 51
+LL L V LL V P CW G CR C ++E Y ILC T CC
Sbjct: 6 VLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCC 65
Query: 52 VDPKYVPV 59
V+PKY+P+
Sbjct: 66 VNPKYLPI 73
>gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens]
Length = 84
Score = 45.4 bits (106), Expect = 1e-05
Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 6/73 (8%)
Query: 1 MKLLLLLLTVTLLLAQVT-----PVMKCWGKSGRCRTTCKESEVYYILCKTEAKCCVDPK 55
MKLL L L + L + + +++C G SG CR +CK++E Y+ C+ CC+
Sbjct: 1 MKLLYLFLAILLAIEEPVISGKRHILRCMGNSGICRASCKKNEQPYLYCRNCQSCCLQ-S 59
Query: 56 YVPVKPKLTDTNT 68
Y+ + + NT
Sbjct: 60 YMRISISGKEENT 72
>gi|46409558 beta-defensin 32 precursor [Homo sapiens]
Length = 95
Score = 43.5 bits (101), Expect = 4e-05
Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 1 MKLLLLLLTVTLLLAQVTPVM----KCWGKS-GRCRTTCKESEVYYILCKTEAKCCVDPK 55
MK LLL+L L QV P KC + G CRT C E +C KCC+
Sbjct: 1 MKFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCCISYS 60
Query: 56 YVPVKPKL 63
++P KP L
Sbjct: 61 FLP-KPDL 67
>gi|76563936 defensin, beta 125 preproprotein [Homo sapiens]
Length = 156
Score = 42.7 bits (99), Expect = 6e-05
Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 5/57 (8%)
Query: 1 MKLLLLLLTVTLLLAQVTP----VMKCWGKS-GRCRTTCKESEVYYILCKTEAKCCV 52
M +L+L + LL +VT KCW + G CR C ++E Y +LC+ + CC+
Sbjct: 1 MNILMLTFIICGLLTRVTKGSFEPQKCWKNNVGHCRRRCLDTERYILLCRNKLSCCI 57
>gi|83582798 beta-defensin 115 [Homo sapiens]
Length = 88
Score = 42.4 bits (98), Expect = 8e-05
Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 7/76 (9%)
Query: 1 MKLLLLLLTVTLLLAQVTP---VMKCWGKSGRCRTTCKESEVYYILCKTEAKCCVDPKYV 57
+KL +L L V ++LAQ P + +C+ +GRCR +CKE E C + CCV PK
Sbjct: 13 IKLSVLALVVLVVLAQTAPDGWIRRCYYGTGRCRKSCKEIERKKEKCGEKHICCV-PK-- 69
Query: 58 PVKPKLTDTNTSLEST 73
K KL+ + E++
Sbjct: 70 -EKDKLSHIHDQKETS 84
>gi|82734223 beta-defensin 124 [Homo sapiens]
Length = 71
Score = 40.4 bits (93), Expect = 3e-04
Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 4/56 (7%)
Query: 1 MKLLLLLLTVTLLLAQV----TPVMKCWGKSGRCRTTCKESEVYYILCKTEAKCCV 52
M LLL L L+L V + +CW G C+T C E Y LC + CC+
Sbjct: 1 MTQLLLFLVALLVLGHVPSGRSEFKRCWKGQGACQTYCTRQETYMHLCPDASLCCL 56
>gi|83582800 beta-defensin 116 [Homo sapiens]
Length = 102
Score = 40.4 bits (93), Expect = 3e-04
Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 14/66 (21%)
Query: 1 MKLLLLLLTVTLLLAQVTP---VMKCWGKS-----------GRCRTTCKESEVYYILCKT 46
MK L+ + + ++LAQ TP GKS G CR C+E E+ Y+ C
Sbjct: 4 MKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPN 63
Query: 47 EAKCCV 52
+ KCC+
Sbjct: 64 DQKCCL 69
>gi|13624333 defensin, beta 126 preproprotein [Homo sapiens]
Length = 111
Score = 37.7 bits (86), Expect = 0.002
Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 8/60 (13%)
Query: 1 MKLLLLLLTVTLLLAQVTP----VMKCWGKSGRCRTTCKESEVY----YILCKTEAKCCV 52
MK LL L V +LLAQ+ V KC G C+ CK E++ + +C + CCV
Sbjct: 1 MKSLLFTLAVFMLLAQLVSGNWYVKKCLNDVGICKKKCKPEEMHVKNGWAMCGKQRDCCV 60
>gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]
Length = 99
Score = 37.4 bits (85), Expect = 0.003
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 6/65 (9%)
Query: 6 LLLTVTLLLAQVTPVM----KCWGK--SGRCRTTCKESEVYYILCKTEAKCCVDPKYVPV 59
L + + +LL Q V KCW G CR C+ +EV LC+ CC++ K +
Sbjct: 3 LFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKELEA 62
Query: 60 KPKLT 64
K+T
Sbjct: 63 CKKIT 67
>gi|169166494 PREDICTED: hypothetical protein [Homo sapiens]
Length = 73
Score = 34.7 bits (78), Expect = 0.017
Identities = 17/63 (26%), Positives = 29/63 (46%), Gaps = 5/63 (7%)
Query: 1 MKLLLLLLTVTLLLAQVTPVMK-----CWGKSGRCRTTCKESEVYYILCKTEAKCCVDPK 55
M++ +LL + ++QV P C +G CR C E+E++ C CC+
Sbjct: 1 MRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCCLPLG 60
Query: 56 YVP 58
+ P
Sbjct: 61 HQP 63
>gi|50344744 beta-defensin 108B [Homo sapiens]
Length = 73
Score = 34.7 bits (78), Expect = 0.017
Identities = 17/63 (26%), Positives = 29/63 (46%), Gaps = 5/63 (7%)
Query: 1 MKLLLLLLTVTLLLAQVTPVMK-----CWGKSGRCRTTCKESEVYYILCKTEAKCCVDPK 55
M++ +LL + ++QV P C +G CR C E+E++ C CC+
Sbjct: 1 MRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSQPCCLPLG 60
Query: 56 YVP 58
+ P
Sbjct: 61 HQP 63
>gi|83582802 beta-defensin 128 [Homo sapiens]
Length = 93
Score = 34.7 bits (78), Expect = 0.017
Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
Query: 1 MKLLLLLLTVTL-LLAQVTPVMKCWGK-SGRCRTTCKESEVYYILCKTEAKCCVD 53
MKL L+L+ + +L + KC+ K +G CR CK E Y I C + CC +
Sbjct: 1 MKLFLVLIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCAN 55
>gi|18250304 beta defensin 129 precursor [Homo sapiens]
Length = 183
Score = 34.7 bits (78), Expect = 0.017
Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 5/61 (8%)
Query: 1 MKLLLLLLTVTLLLAQVTP----VMKCWGKSGRCRTTCKESEVYYILCKTEAKCCVDPKY 56
MKLL + +L QV + +C GRCR C E CK + KCCV PK
Sbjct: 1 MKLLFPIFASLMLQYQVNTEFIGLRRCLMGLGRCRDHCNVDEKEIQKCKMK-KCCVGPKV 59
Query: 57 V 57
V
Sbjct: 60 V 60
>gi|103485139 defensin, beta 104A precursor [Homo sapiens]
Length = 72
Score = 34.3 bits (77), Expect = 0.022
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 7/59 (11%)
Query: 1 MKLLLLLLTVTLLLAQVTPVMK-------CWGKSGRCRTTCKESEVYYILCKTEAKCCV 52
M+ L+LLL ++LLL Q PV C + RCR C+ E C CC+
Sbjct: 1 MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCL 59
>gi|103485137 defensin, beta 104B precursor [Homo sapiens]
Length = 72
Score = 34.3 bits (77), Expect = 0.022
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 7/59 (11%)
Query: 1 MKLLLLLLTVTLLLAQVTPVMK-------CWGKSGRCRTTCKESEVYYILCKTEAKCCV 52
M+ L+LLL ++LLL Q PV C + RCR C+ E C CC+
Sbjct: 1 MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCL 59
>gi|239753808 PREDICTED: hypothetical protein [Homo sapiens]
Length = 83
Score = 33.1 bits (74), Expect = 0.050
Identities = 16/63 (25%), Positives = 29/63 (46%), Gaps = 5/63 (7%)
Query: 1 MKLLLLLLTVTLLLAQVTPVMK-----CWGKSGRCRTTCKESEVYYILCKTEAKCCVDPK 55
+++ +LL + ++QV P C +G CR C E+E++ C CC+
Sbjct: 11 VRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCCLPLG 70
Query: 56 YVP 58
+ P
Sbjct: 71 HQP 73
>gi|239748372 PREDICTED: hypothetical protein [Homo sapiens]
Length = 83
Score = 33.1 bits (74), Expect = 0.050
Identities = 16/63 (25%), Positives = 29/63 (46%), Gaps = 5/63 (7%)
Query: 1 MKLLLLLLTVTLLLAQVTPVMK-----CWGKSGRCRTTCKESEVYYILCKTEAKCCVDPK 55
+++ +LL + ++QV P C +G CR C E+E++ C CC+
Sbjct: 11 VRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCCLPLG 70
Query: 56 YVP 58
+ P
Sbjct: 71 HQP 73
>gi|74136827 beta-defensin 134 [Homo sapiens]
Length = 66
Score = 33.1 bits (74), Expect = 0.050
Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 22 KCWGKSGRCRTTCKESEVYYILCKTEAKCCVDPKYVP 58
KC+ K+G CR C ESE+ C + +CCV P
Sbjct: 31 KCY-KNGICRLECYESEMLVAYCMFQLECCVKGNPAP 66
>gi|22748611 defensin, beta 106A precursor [Homo sapiens]
Length = 65
Score = 31.2 bits (69), Expect = 0.19
Identities = 16/54 (29%), Positives = 21/54 (38%), Gaps = 3/54 (5%)
Query: 1 MKLLLLLLTVTLLLAQVTPVM---KCWGKSGRCRTTCKESEVYYILCKTEAKCC 51
M+ L L V L KC G C+ C ++E LC+ KCC
Sbjct: 1 MRTFLFLFAVLFFLTPAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCC 54
>gi|103485143 defensin, beta 106B precursor [Homo sapiens]
Length = 65
Score = 31.2 bits (69), Expect = 0.19
Identities = 16/54 (29%), Positives = 21/54 (38%), Gaps = 3/54 (5%)
Query: 1 MKLLLLLLTVTLLLAQVTPVM---KCWGKSGRCRTTCKESEVYYILCKTEAKCC 51
M+ L L V L KC G C+ C ++E LC+ KCC
Sbjct: 1 MRTFLFLFAVLFFLTPAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCC 54
>gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens]
Length = 53
Score = 30.8 bits (68), Expect = 0.25
Identities = 12/30 (40%), Positives = 13/30 (43%)
Query: 23 CWGKSGRCRTTCKESEVYYILCKTEAKCCV 52
CW G CR CK E CK CC+
Sbjct: 18 CWIIKGHCRKNCKPGEQVKKPCKNGDYCCI 47
>gi|239751980 PREDICTED: defensin, beta 117 [Homo sapiens]
Length = 53
Score = 30.8 bits (68), Expect = 0.25
Identities = 12/30 (40%), Positives = 13/30 (43%)
Query: 23 CWGKSGRCRTTCKESEVYYILCKTEAKCCV 52
CW G CR CK E CK CC+
Sbjct: 18 CWIIKGHCRKNCKPGEQVKKPCKNGDYCCI 47
>gi|239746467 PREDICTED: defensin, beta 117 [Homo sapiens]
Length = 53
Score = 30.8 bits (68), Expect = 0.25
Identities = 12/30 (40%), Positives = 13/30 (43%)
Query: 23 CWGKSGRCRTTCKESEVYYILCKTEAKCCV 52
CW G CR CK E CK CC+
Sbjct: 18 CWIIKGHCRKNCKPGEQVKKPCKNGDYCCI 47
>gi|239744548 PREDICTED: hypothetical protein XP_002343194 [Homo
sapiens]
Length = 192
Score = 30.4 bits (67), Expect = 0.32
Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 6/55 (10%)
Query: 3 LLLLLLTVTLLLAQVTPVM-----KCWGKSGRCRT-TCKESEVYYILCKTEAKCC 51
LLL+LL ++LL+ V + C SG CR CK E C+ KCC
Sbjct: 69 LLLILLLFSILLSPVRGALGPAEVHCLSLSGVCRRDVCKVVEDQIGACRRRMKCC 123
>gi|82734219 beta-defensin 114 [Homo sapiens]
Length = 69
Score = 30.4 bits (67), Expect = 0.32
Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 6/53 (11%)
Query: 5 LLLLTVTLLLAQVTPVMKCWGKSGRCRTTCKESEVYYILCKTEAK-CCVDPKY 56
+L T TL+ A +C + GRC+ C ESE +C K CC + Y
Sbjct: 16 ILPATCTLVNAD-----RCTKRYGRCKRDCLESEKQIDICSLPRKICCTEKLY 63
>gi|4506105 prolactin precursor [Homo sapiens]
Length = 227
Score = 29.3 bits (64), Expect = 0.72
Identities = 14/34 (41%), Positives = 21/34 (61%)
Query: 3 LLLLLLTVTLLLAQVTPVMKCWGKSGRCRTTCKE 36
LLLLL++ LL V P+ C G + RC+ T ++
Sbjct: 12 LLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRD 45
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.132 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,609,167
Number of Sequences: 37866
Number of extensions: 91540
Number of successful extensions: 239
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 205
Number of HSP's gapped (non-prelim): 33
length of query: 76
length of database: 18,247,518
effective HSP length: 48
effective length of query: 28
effective length of database: 16,429,950
effective search space: 460038600
effective search space used: 460038600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Search text |
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.