Guide to the Human Genome
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Name: PRL Sequence: fasta or formatted (227aa) NCBI GI: 4506105
Description:

prolactin precursor

Referenced in:

Proteins Measured in Common Diagnostic Tests
Growth Hormone and Related Hormones
Ovary, Uterus and Placenta
Pituitary

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.3         12           2
 C cysteine            3.1          7           1
 D aspartate           3.5          8           1
 E glutamate           7.9         18           2
 F phenylalanine       2.2          5           1
 G glycine             4.0          9           2
 H histidine           4.0          9           1
 I isoleucine          6.2         14           2
 K lysine              5.3         12           1
 L leucine            14.1         32           5
 M methionine          2.6          6           1
 N asparagine          5.3         12           3
 P proline             4.4         10           1
 Q glutamine           4.4         10           2
 R arginine            5.3         12           2
 S serine              9.3         21           2
 T threonine           3.5          8           1
 V valine              5.3         12           2
 W tryptophan          1.3          3           1
 Y tyrosine            3.1          7           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   prolactin precursor 
GH1                   0.115   growth hormone 1 isoform 1 
GH1                   0.108   growth hormone 1 isoform 2 
CSH1                  0.101   chorionic somatomammotropin hormone 1 isoform 1 [Homo...
CSH2                  0.101   chorionic somatomammotropin hormone 2 isoform 1 [Hom...
GH2                   0.089   growth hormone 2 isoform 1 
GH2                   0.083   growth hormone 2 isoform 4 
CSHL1                 0.071   chorionic somatomammotropin hormone-like 1 isoform 1...
CSH1                  0.067   chorionic somatomammotropin hormone 1 isoform 2 [Hom...
CSH2                  0.067   chorionic somatomammotropin hormone 2 isoform 2 [Hom...
CSHL1                 0.067   chorionic somatomammotropin hormone-like 1 isoform 2...
GH2                   0.048   growth hormone 2 isoform 3 
GH2                   0.048   growth hormone 2 isoform 2 
GH1                   0.048   growth hormone 1 isoform 3 
CCDC136               0.037   coiled-coil domain containing 136 
CSHL1                 0.032   chorionic somatomammotropin hormone-like 1 isoform 4...
CSHL1                 0.025   chorionic somatomammotropin hormone-like 1 isoform 3...
N4BP1                 0.023   Nedd4 binding protein 1 
GH1                   0.021   growth hormone 1 isoform 4 
LOC100293689          0.021   PREDICTED: similar to chorionic somatomammotropin h...
CSH1                  0.021   chorionic somatomammotropin hormone 1 isoform 3 [Hom...
CSH2                  0.021   chorionic somatomammotropin hormone 2 isoform 3 [Hom...
HEG1                  0.016   HEG homolog 1 
HIVEP2                0.014   human immunodeficiency virus type I enhancer bindin...
EFCAB5                0.011   EF-hand calcium binding domain 5 isoform a 
PVRL4                 0.011   poliovirus receptor-related 4 
SVIL                  0.009   supervillin isoform 2 
INPP4B                0.009   inositol polyphosphate-4-phosphatase, type II, 105k...
INPP4B                0.009   inositol polyphosphate-4-phosphatase, type II, 105k...
DEFB121               0.009   defensin, beta 121 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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