Guide to the Human Genome
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Search of human proteins with 57864582

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|57864582 hornerin [Homo sapiens]
         (2850 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|57864582 hornerin [Homo sapiens]                                  5881   0.0  
gi|62122917 filaggrin family member 2 [Homo sapiens]                 1315   0.0  
gi|60097902 filaggrin [Homo sapiens]                                  903   0.0  
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]   262   3e-69
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                       219   4e-56
gi|171916097 repetin [Homo sapiens]                                   197   2e-49
gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo sa...   181   1e-44
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma...   139   4e-32
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]         133   3e-30
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]          128   9e-29
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]       127   2e-28
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                       126   3e-28
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...   126   3e-28
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...   119   3e-26
gi|7706635 cornulin [Homo sapiens]                                    118   7e-26
gi|239757861 PREDICTED: similar to armadillo repeat containing, ...   117   2e-25
gi|109255251 loricrin [Homo sapiens]                                  117   2e-25
gi|89276766 trophinin isoform 5 [Homo sapiens]                        112   7e-24
gi|239744892 PREDICTED: hypothetical protein XP_002344252 [Homo ...   111   9e-24
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]    109   3e-23
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]    109   3e-23
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...   105   6e-22
gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo ...   105   8e-22
gi|186928827 dermokine isoform 5 precursor [Homo sapiens]             105   8e-22
gi|186928829 dermokine isoform 4 precursor [Homo sapiens]             104   1e-21
gi|28559039 mediator complex subunit 1 [Homo sapiens]                 104   1e-21
gi|186928825 dermokine isoform 3 precursor [Homo sapiens]             103   2e-21
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]           103   2e-21
gi|33504489 dermokine isoform 2 precursor [Homo sapiens]              102   4e-21
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...   102   4e-21

>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 5881 bits (15258), Expect = 0.0
 Identities = 2850/2850 (100%), Positives = 2850/2850 (100%)

Query: 1    MPKLLQGVITVIDVFYQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQS 60
            MPKLLQGVITVIDVFYQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQS
Sbjct: 1    MPKLLQGVITVIDVFYQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQS 60

Query: 61   LDRDHNKKVDFTEYLLMIFKLVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEEN 120
            LDRDHNKKVDFTEYLLMIFKLVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEEN
Sbjct: 61   LDRDHNKKVDFTEYLLMIFKLVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEEN 120

Query: 121  KRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYG 180
            KRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYG
Sbjct: 121  KRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYG 180

Query: 181  EQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQ 240
            EQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQ
Sbjct: 181  EQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQ 240

Query: 241  SSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQG 300
            SSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQG
Sbjct: 241  SSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQG 300

Query: 301  SGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSG 360
            SGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSG
Sbjct: 301  SGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSG 360

Query: 361  YSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGS 420
            YSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGS
Sbjct: 361  YSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGS 420

Query: 421  GQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQ 480
            GQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQ
Sbjct: 421  GQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQ 480

Query: 481  HGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQS 540
            HGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQS
Sbjct: 481  HGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQS 540

Query: 541  PSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQH 600
            PSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQH
Sbjct: 541  PSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQH 600

Query: 601  GSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSP 660
            GSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSP
Sbjct: 601  GSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSP 660

Query: 661  SRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGS 720
            SRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGS
Sbjct: 661  SRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGS 720

Query: 721  SHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVR 780
            SHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVR
Sbjct: 721  SHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVR 780

Query: 781  HGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSS 840
            HGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSS
Sbjct: 781  HGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSS 840

Query: 841  QGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGS 900
            QGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGS
Sbjct: 841  QGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGS 900

Query: 901  GQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQH 960
            GQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQH
Sbjct: 901  GQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQH 960

Query: 961  GSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQ 1020
            GSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQ
Sbjct: 961  GSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQ 1020

Query: 1021 SSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG 1080
            SSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG
Sbjct: 1021 SSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG 1080

Query: 1081 STSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPS 1140
            STSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPS
Sbjct: 1081 STSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPS 1140

Query: 1141 YGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS 1200
            YGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS
Sbjct: 1141 YGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS 1200

Query: 1201 GQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQ 1260
            GQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQ
Sbjct: 1201 GQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQ 1260

Query: 1261 HGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQS 1320
            HGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQS
Sbjct: 1261 HGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQS 1320

Query: 1321 STFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGS 1380
            STFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGS
Sbjct: 1321 STFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGS 1380

Query: 1381 GSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRG 1440
            GSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRG
Sbjct: 1381 GSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRG 1440

Query: 1441 ERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSG 1500
            ERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSG
Sbjct: 1441 ERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSG 1500

Query: 1501 SGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG 1560
            SGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG
Sbjct: 1501 SGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG 1560

Query: 1561 QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGR 1620
            QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGR
Sbjct: 1561 QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGR 1620

Query: 1621 SSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG 1680
            SSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG
Sbjct: 1621 SSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG 1680

Query: 1681 SSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSS 1740
            SSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSS
Sbjct: 1681 SSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSS 1740

Query: 1741 RGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST 1800
            RGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST
Sbjct: 1741 RGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST 1800

Query: 1801 GQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGR 1860
            GQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGR
Sbjct: 1801 GQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGR 1860

Query: 1861 HGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSS 1920
            HGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSS
Sbjct: 1861 HGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSS 1920

Query: 1921 SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPY 1980
            SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPY
Sbjct: 1921 SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPY 1980

Query: 1981 ESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSS 2040
            ESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSS
Sbjct: 1981 ESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSS 2040

Query: 2041 SHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPG 2100
            SHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPG
Sbjct: 2041 SHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPG 2100

Query: 2101 LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYG 2160
            LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYG
Sbjct: 2101 LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYG 2160

Query: 2161 QHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGH 2220
            QHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGH
Sbjct: 2161 QHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGH 2220

Query: 2221 SSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHG 2280
            SSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHG
Sbjct: 2221 SSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHG 2280

Query: 2281 SGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSG 2340
            SGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSG
Sbjct: 2281 SGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSG 2340

Query: 2341 FGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGS 2400
            FGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGS
Sbjct: 2341 FGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGS 2400

Query: 2401 RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGL 2460
            RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGL
Sbjct: 2401 RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGL 2460

Query: 2461 GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS 2520
            GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS
Sbjct: 2461 GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS 2520

Query: 2521 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 2580
            QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH
Sbjct: 2521 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 2580

Query: 2581 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS 2640
            ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS
Sbjct: 2581 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS 2640

Query: 2641 GHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESG 2700
            GHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESG
Sbjct: 2641 GHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESG 2700

Query: 2701 SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYG 2760
            SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYG
Sbjct: 2701 SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYG 2760

Query: 2761 RHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHD 2820
            RHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHD
Sbjct: 2761 RHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHD 2820

Query: 2821 GGSSGSYFLSFPSSTSPYEYVQEQRCYFYQ 2850
            GGSSGSYFLSFPSSTSPYEYVQEQRCYFYQ
Sbjct: 2821 GGSSGSYFLSFPSSTSPYEYVQEQRCYFYQ 2850


>gi|62122917 filaggrin family member 2 [Homo sapiens]
          Length = 2391

 Score = 1315 bits (3402), Expect = 0.0
 Identities = 985/2447 (40%), Positives = 1212/2447 (49%), Gaps = 422/2447 (17%)

Query: 1    MPKLLQGVITVIDVFYQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQS 60
            M  LL+ V+TVIDVFY+Y  Q GE  TL+K ELKELLE E H +LKNP+DPDTVD+I+  
Sbjct: 1    MTDLLRSVVTVIDVFYKYTKQDGECGTLSKGELKELLEKELHPVLKNPDDPDTVDVIMHM 60

Query: 61   LDRDHNKKVDFTEYLLMIFKLVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEEN 120
            LDRDH++++DFTE+LLMIFKL  A NK++ K+YC+ SGSK     H+HQEE+ ETE++E 
Sbjct: 61   LDRDHDRRLDFTEFLLMIFKLTMACNKVLSKEYCKASGSKKHRRGHRHQEEESETEEDEE 120

Query: 121  KR--QESSFSHSSWSAGENDSYSR-NVRGSLKPGTESISRRLSFQRDFSGQHN------- 170
                 +S + HSSWS GE   YS  + RG++K    S SRRL  Q + S   N       
Sbjct: 121  DTPGHKSGYRHSSWSEGEEHGYSSGHSRGTVKCRHGSNSRRLGRQGNLSSSGNQEGSQKR 180

Query: 171  --------SYSGQSSSYGEQN------------SDSHQSSGRGQCGSGSGQSPNYGQHG- 209
                    S+SG    +G  +            S S +S    + GSGS      G  G 
Sbjct: 181  YHRSSCGHSWSGGKDRHGSSSVELRERINKSHISPSRESGEEYESGSGSNSWERKGHGGL 240

Query: 210  ---------------------------SGSGQSSSNDTHGSGSGQSSGFS--QHKSSSGQ 240
                                       SGSG S    +H  G   SSG    Q+ SSS Q
Sbjct: 241  SCGLETSGHESNSTQSRIREQKLGSSCSGSGDSGRR-SHACGYSNSSGCGRPQNASSSCQ 299

Query: 241  SS---------GYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSY-------- 283
            S           Y Q G  SG   G G HG  SG    G     S+  S SY        
Sbjct: 300  SHRFGGQGNQFSYIQSGCQSGIKGGQG-HGCVSGGQPSGCGQPESNPCSQSYSQRGYGAR 358

Query: 284  ----------------------GQHGSGSRQSLGHGRQ---------------------- 299
                                  GQ+GSG  QS  +G+                       
Sbjct: 359  ENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQ 418

Query: 300  -GSGSRQSPSHVRHGSGSGHSSSH-----------GQHGSGSSYSYSRGHYESGSGQTSG 347
             GSGS QS S  +HG+G   SS             GQH S SS S     + S SG+TSG
Sbjct: 419  YGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSG 478

Query: 348  FGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESAS 407
            FGQH SGSGQSSG+ + GSGSG SS  GQHGS SGQ+S  GQHGS S QSS +GQHES S
Sbjct: 479  FGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRS 538

Query: 408  RHSSGRGQHSSGSGQSPGHGQRGS-----------GSGQSPSSGQHGTGFGRSSSSGPYV 456
            R SS  GQH SGS QS G+GQ GS           GSGQS   GQ+G+G G+SS  G + 
Sbjct: 539  RQSS-YGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHG 597

Query: 457  SGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSS 516
            SGSG SSGFG HES S  SS Y QH SGS  SSG+GQHGSR  Q+S   + GS +  S+ 
Sbjct: 598  SGSGQSSGFGQHESRSGQSS-YGQHSSGSSQSSGYGQHGSR--QTSGFGQHGSGSSQSTG 654

Query: 517  YGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES 576
            +GQ+GSGS QS G  +H SGSGQ  S   G+HES S   SSYG HG+GS +SS  G + S
Sbjct: 655  FGQYGSGSGQSSGFGQHVSGSGQ--SSGFGQHESRSGH-SSYGQHGFGSSQSSGYGQHGS 711

Query: 577  GSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSH 636
             SG +SG G  E  SGQSS +GQHGS SG SS  GQHGS SGQSS  GQH + SGQ SS+
Sbjct: 712  SSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQ-SSY 770

Query: 637  GQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSG 696
            GQH SGSSQSS YGQ   GS Q+   G+HGS    S+ +GQ+GSGSG S+  G HGS SG
Sbjct: 771  GQHSSGSSQSSGYGQH--GSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSG 828

Query: 697  QSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHG 756
            QSSGFG        S Y QHGSGSS SSGY +HGS SGQ+S   QH SSSG  S +GQHG
Sbjct: 829  QSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHG 888

Query: 757  SGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASG 816
            SGS QSSG G+ G+GSG      +H S S H SS+GQHGSG+S SS  G + S SGQ  G
Sbjct: 889  SGSGQSSGFGQHGTGSGQYSGFGQHESRS-HQSSYGQHGSGSSQSSGYGQHGSSSGQTFG 947

Query: 817  FGQHESGSGQ--GYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESAS 874
            FGQH SGSGQ  G+ QHGS SG  S  G+H S SG+SS  GQH+S S Q S+YGQH S S
Sbjct: 948  FGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQ-SNYGQHGSGS 1006

Query: 875  HHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGH 934
              +SG G+HGS SGQ+ G GQ  S SGQ   +G+HGSGS +SS  G+HG+GSGQSSGFG 
Sbjct: 1007 SQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQ 1066

Query: 935  KSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSL 994
              S  + S Y QHGSGS  SS Y QHGS SGQ+S   QH   SG SS +GQ+GSGS QS 
Sbjct: 1067 YESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSS 1126

Query: 995  GHGQHGSGSGQSP----------SPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGS 1044
            G GQHGSG+G+S             S G+HG+GS QSS  G + SGSG ++S G + SGS
Sbjct: 1127 GFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGS 1186

Query: 1045 GHSSGLGHRESRSGQSSGYGQHGSSSGH---------------SSTHGQHGSTSGQSSSC 1089
             + S  G   S SGQS+G+GQ+GS SG                S+ HG+  +T GQ+ + 
Sbjct: 1187 DNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETTHGQTINT 1246

Query: 1090 GQHGAS-SGQSSSHGQHGS---GSSQS------------------------SGYGRQGSG 1121
             +H  S  GQS+  G   +    SSQS                        S Y + GS 
Sbjct: 1247 TRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGST 1306

Query: 1122 SGQSPG--HGQRG-------SGSRQSPSYGRHGSGSGRSSSS------------------ 1154
              +  G  HGQRG       SG  QS   G   SG  R S S                  
Sbjct: 1307 VRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQ 1366

Query: 1155 ----GQHGSGLGESSGFGH--HESSSGQSSSYSQHG-SGSGHSSGYGQHGSRSGQSSRGE 1207
                 Q GS  GES    H  HE++ GQ+   + HG SG G S+   Q GSR+    RG 
Sbjct: 1367 EQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQST---QRGSRT-TGRRGS 1422

Query: 1208 RHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPS--RGRHGSGLGHSS-----SHGQ 1260
             H  SS S  H G       Q   HG+ GS  G S S   GRHG+  G +      +H  
Sbjct: 1423 GHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYH 1482

Query: 1261 HGSGSGRSSS----RGPYESRSGHSSVF--GQH-ESGSGHSSAYSQHGSGSG-----HFC 1308
            HG  + R SS    RG   S S  S V   G H  SG  H  + SQHG         H  
Sbjct: 1483 HGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESIIHDRHRI 1542

Query: 1309 SQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSR----GR 1364
            + GQ G T+  S +  ++ + TG S + G + +  S+S+    H  GS +  SR    G+
Sbjct: 1543 THGQTGDTTRHSYSGHEQTTQTG-SRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTYGQ 1601

Query: 1365 HGS---------GSGHSSSYGQHGSGSGWSSS------------SGRHGSGSGQSSGFGH 1403
             GS            H +++GQ G  +G S S            +GR  S   +SS    
Sbjct: 1602 AGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHSESSDSEV 1661

Query: 1404 HESSSWQSSGCTQHGSGSGHSSSY----EQHGSRSGQSSRGERHG------SSSGSSSSY 1453
            H   S   +G T   +GS H  S     E+HG+  GQ+    RH       ++   S + 
Sbjct: 1662 HSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRHAHYHHGLTTQTGSRTT 1721

Query: 1454 GQHGSG---------------SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYG 1498
            G+ GSG               +     HGQ  S  G+S S    RHG+  GQ+   + + 
Sbjct: 1722 GRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGTIHGQTGDTTRHA 1781

Query: 1499 -SGSGWSSSRGPYESGSSHSSGLGHRE-SRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 1556
             SG G S+  G   +G   S   GH E S S   SG+ Q   S GH  THGQ GS  G+S
Sbjct: 1782 HSGHGQSTQTGSRTTGRRSS---GHSEYSDSEGHSGFSQRPHSRGH--THGQAGSQHGES 1836

Query: 1557 SSC--GQHGASSGQ---SSSHGQHGSGSSQSSG---YGRQGSGSGQSPGHGQRGSGSRQS 1608
             S    +HG + GQ   +S H Q G G S  SG    GR+ SG  +S        GS   
Sbjct: 1837 ESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDSEVHSGGSHTH 1896

Query: 1609 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHG---SGSGHSSGYGQ 1665
                   SG   S +  QHG    ES+    H+++ GQ+   ++HG    G    +G   
Sbjct: 1897 -------SGHTHSQARSQHGE--SESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRT 1947

Query: 1666 HGSR-SGQSSRGERHG----SSSRSSSRYGQHGSGSRQ--SSGHGRQGSGSGQSPSRGRH 1718
             G R SG S   +  G    S + S   +GQ GS   +  SS H R G+  GQ+    RH
Sbjct: 1948 TGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRH 2007

Query: 1719 G-SGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHG-SGSGH 1776
            G SG G S+  G   +G  R+S    Y    GHS V   H SG  H  A SQHG SGS  
Sbjct: 2008 GHSGHGQSTQRGSRTTGR-RASGHSEYSDSEGHSGVSHTH-SGHAHGQAGSQHGESGSS- 2064

Query: 1777 FCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQ---SSSYGQQGSGSGQSPSRG 1833
                 +HG+T GQ          TG ++ H   G G S    S + G++GSG  +S    
Sbjct: 2065 --VHERHGTTHGQ----------TGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSE 2112

Query: 1834 RHGSGSGHSSS---YGQHGSGSGWSSSS--GRHGSGSGQSSGFGHHESSSWQSSGYTQHG 1888
             H SG  H+ S   YGQ  S  G S S+  GR G+  G             Q+   T+HG
Sbjct: 2113 VH-SGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHG-------------QTGDTTRHG 2158

Query: 1889 SGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSS-SSYGQHGSGSRQSLGHGQHGSGSGQSP 1947
              SGH  S     +++G  + G Q  S S SS S      S +     H Q GS  GQS 
Sbjct: 2159 Q-SGHGQS-----TQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSG 2212

Query: 1948 SPSRGRHGSGSGQSSSYGPYGS-GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQH 2006
            S   GR G+  GQ+     +   G G S+ RG   +G     G GH ES   +   +G H
Sbjct: 2213 SSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTG---RRGSGHSESSDSEVHSWGSH 2269

Query: 2007 GSSSGH-------------SSTHGQHGSASGQSSSCGQHGASS-GQSSSHGQHGSGSS-- 2050
             + SGH             S+ HG+  +  GQ+    +HG S  GQS+  G   S +S  
Sbjct: 2270 -THSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQSTQTGSRSSRASHF 2328

Query: 2051 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH 2097
            QS    RQ  GS Q   HG  G         G   SG  R S S  H
Sbjct: 2329 QSHSSERQRHGSSQVWKHGSYGPAEYDYGHTGYGPSGGSRKSISNSH 2375



 Score = 1248 bits (3230), Expect = 0.0
 Identities = 925/2259 (40%), Positives = 1164/2259 (51%), Gaps = 226/2259 (10%)

Query: 710  SSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQH--GSSSGLSSSYGQHGSGSHQSSGHGR 767
            S  Y +      H  G+R H     ++   E+   G  SG   S    G     SSGH R
Sbjct: 90   SKEYCKASGSKKHRRGHR-HQEEESETEEDEEDTPGHKSGYRHSSWSEGEEHGYSSGHSR 148

Query: 768  QGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCS-SSCGHYESGSGQASGFGQHESGSGQ 826
                  H  +  R G     SSS  Q GS      SSCGH  SG                
Sbjct: 149  GTVKCRHGSNSRRLGRQGNLSSSGNQEGSQKRYHRSSCGHSWSG---------------- 192

Query: 827  GYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSG 886
            G  +HGS+S     +      S    S  +++S SG +S   +             H S 
Sbjct: 193  GKDRHGSSSVELRERINKSHISPSRESGEEYESGSGSNSWERKGHGGLSCGLETSGHESN 252

Query: 887  SGQSPGHGQR-GSGSGQSPSYGRHGSGSGRSSSSG----RHGSGSGQSSGFGHKSSSGQS 941
            S QS    Q+ GS    S   GR     G S+SSG    ++ S S QS  FG     G  
Sbjct: 253  STQSRIREQKLGSSCSGSGDSGRRSHACGYSNSSGCGRPQNASSSCQSHRFG---GQGNQ 309

Query: 942  SGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGS 1001
              Y Q G  SG     + HG  SG          S+  S SY Q G G+R++ G  Q+  
Sbjct: 310  FSYIQSGCQSGIKGG-QGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGAREN-GQPQNCG 367

Query: 1002 G---SGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSG 1058
            G   +G S S   G++GSG  QS S G +  GS     R    S S   S      S S 
Sbjct: 368  GQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGS---CGRFSNSSSSNEFSKCDQYGSGSS 424

Query: 1059 QSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 1118
            QS+ + QHG+    SS   QH   SGQ+  CGQH ++S QS  + QHGS S ++SG+G+ 
Sbjct: 425  QSTSFEQHGTGLSQSSGFEQHVCGSGQT--CGQHESTSSQSLGYDQHGSSSGKTSGFGQH 482

Query: 1119 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSS 1178
            GSGSGQS G GQ GSGS QS  +G+HGS SG+SS  GQHGS  G+SSGFG HES S QSS
Sbjct: 483  GSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSS 542

Query: 1179 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSG 1238
             Y QHGSGS  SSGYGQ+GSR  ++S   +HG  SG S+ +GQ+GSGS QSSG G+ GSG
Sbjct: 543  -YGQHGSGSSQSSGYGQYGSR--ETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSG 599

Query: 1239 SGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYS 1298
            SG S   G+H S  G SS +GQH SGS +SS  G + SR   +S FGQH SGS  S+ + 
Sbjct: 600  SGQSSGFGQHESRSGQSS-YGQHSSGSSQSSGYGQHGSRQ--TSGFGQHGSGSSQSTGFG 656

Query: 1299 QHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQ 1358
            Q+GSGSG     GQH S SGQSS F Q  S +G SS YG  G GSSQSSGYG+HG+ SGQ
Sbjct: 657  QYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSS-YGQHGFGSSQSSGYGQHGSSSGQ 715

Query: 1359 SPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHG 1418
            +   G+H   SG SSS+GQHGSGSG SS  G+HGSGSGQSSGFG HES S QSS   QH 
Sbjct: 716  TSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSS-YGQHS 774

Query: 1419 SGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS 1478
            SGS  SS Y QHGSR  Q+S   +HGS S  S+ +GQ+GSGS QS G GQHGSGSGQS  
Sbjct: 775  SGSSQSSGYGQHGSR--QTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSG 832

Query: 1479 PSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGS 1538
               G+H S S QSS Y  +GSGS  SS  G + S S  +SG G   S SGQ SG+GQHGS
Sbjct: 833  --FGQHESRSHQSS-YGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGS 889

Query: 1539 SSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGH 1598
             SG SS  GQHG+ SGQ S  GQH + S Q SS+GQHGSGSSQSSGYG+ GS SGQ+ G 
Sbjct: 890  GSGQSSGFGQHGTGSGQYSGFGQHESRSHQ-SSYGQHGSGSSQSSGYGQHGSSSGQTFGF 948

Query: 1599 GQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSG 1658
            GQ  SGS QS  +G+HGSGSG+SS  GQH SG G+SSGFG HES S Q S+Y QHGSGS 
Sbjct: 949  GQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQ-SNYGQHGSGSS 1007

Query: 1659 HSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRH 1718
             SSGYGQHGS SGQ++   +H SSS   S +GQHGSGS QSSG G+ G+GSGQS   G++
Sbjct: 1008 QSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQY 1067

Query: 1719 GSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFC 1778
             S     SS+GQHGSGS +SS  G + S SG +S FGQH  GSG SS + Q+GSGSG   
Sbjct: 1068 ES-RSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSS 1126

Query: 1779 SQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSG 1838
              GQHGS +G+SS F Q    +GQ SS+GQHG+GSSQSS  GQ  SGSG + S G+H SG
Sbjct: 1127 GFGQHGSGTGKSSGFAQHEYRSGQ-SSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSG 1185

Query: 1839 SGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHG---------- 1888
            S + SS GQH S SG S+  G++GSGSGQS+G G  ES   + SG T HG          
Sbjct: 1186 SDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVE-SGSTVHGRQETTHGQTI 1244

Query: 1889 SGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLG-HGQHGSGSGQSP 1947
            + + HS S +   +++G      +  S S +S S        R S   H Q GS   +S 
Sbjct: 1245 NTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSG 1304

Query: 1948 SPSRGRHGSGSGQSSSYGPYG-SGSGWSSSRGPYESGS---GHS--------SGLGHRES 1995
            S  R R G+  GQ      +G SG G S+  G   SG     HS        SG+ HR  
Sbjct: 1305 STVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPH 1364

Query: 1996 RSGQ--SSGYGQHGSSSG-----HSSTHGQHGSASGQSSSCGQHGASSGQSS-SHGQHGS 2047
               Q  S    QHG S       H +T+GQ G A+G   S   HG S+ + S + G+ GS
Sbjct: 1365 SQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHS--GHGQSTQRGSRTTGRRGS 1422

Query: 2048 GSSQSSGYGRQGSGS----GQSPGHGQRGS--GSRQSPSYGRHGSGSGRSSSSGQH---- 2097
            G S+SS       GS     Q   HGQ GS  G   S  +GRHG+  G++  + +H    
Sbjct: 1423 GHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYH 1482

Query: 2098 -------GPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR--GER 2148
                   G       G GH ESS  +  S   H + SGH+  +GQ GS+ G+S     +R
Sbjct: 1483 HGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSH-THSGHT--HGQSGSQHGESESIIHDR 1539

Query: 2149 HGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRS 2208
            H  +      +GQ G  +R S     Q + +G S + GR  +    S+    H  GS R 
Sbjct: 1540 HRIT------HGQTGDTTRHSYSGHEQTTQTG-SRTTGRQRTSHSESTDSEVHSGGSHRP 1592

Query: 2209 SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHG-STSGQSSTFDQEG 2267
             SR     ++G      +      H + + Q G  +GH  S   HG ST   S T  ++ 
Sbjct: 1593 HSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGH--SHSGHGQSTQRGSRTTGRQR 1650

Query: 2268 SSTGQSSSHGQHG--SGSSQSSSYGQQGSGSGQSPS--RGRHGSGSGHSSSYGQHG---- 2319
            SS  +SS    H   S +    ++GQ GS  GQS S    RHG+  G +    +H     
Sbjct: 1651 SSHSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRHAHYHH 1710

Query: 2320 --SGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSS----YEQHGSR 2373
              +    S ++GR GSG  + S    +   S   SG+T   + S H  S    +E+HG+ 
Sbjct: 1711 GLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGTI 1770

Query: 2374 SGQSSRGERHG-SSSGSSSSYGQHGSGSRQS----------------------LGHGQHG 2410
             GQ+    RH  S  G S+  G   +G R S                        HGQ G
Sbjct: 1771 HGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAG 1830

Query: 2411 SGSGQSPSPSRGRHGSGSGQSSSYSPYG-SGSGWSSSRGPYESG---SGHS--------S 2458
            S  G+S S    RHG+  GQ+   S +  SG G S+  G   +G   SGHS        S
Sbjct: 1831 SQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDSEVHS 1890

Query: 2459 GLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHG-ASSGQ-----SSSH 2512
            G  H  S    S    QHG S   S+ H +H +T GQ+    +HG  S GQ     S + 
Sbjct: 1891 GGSHTHSGHTHSQARSQHGES--ESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTT 1948

Query: 2513 GQHGSGSSQ-SSGYGRQG-SGSGQSPGHGQRGSGSRQSPS--YGRHGSGSGRSSSSGQHG 2568
            G+ GSG S+ S   G  G S +     HGQ GS   +S S  + RHG+  G+++ + +HG
Sbjct: 1949 GRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHG 2008

Query: 2569 -SGLGESSGFGHHESSSGQSSSYSQHGSGSGHSS--------GYGQHGSRSGQ--SSRGE 2617
             SG G+S+  G   ++  ++S +S++    GHS          +GQ GS+ G+  SS  E
Sbjct: 2009 HSGHGQSTQRG-SRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSSVHE 2067

Query: 2618 RHGSSSGSS------SHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSS---- 2667
            RHG++ G +      +H G   S  R S   GR+GSG  +S     H SG+ H+ S    
Sbjct: 2068 RHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVH-SGVSHTHSGHTY 2126

Query: 2668 ---HGQHG-SGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSG---SGHFCSQ 2720
                 QHG SGS     +G    + G ++  GQ  SG G S+      +G   S H  S 
Sbjct: 2127 GQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQ--SGHGQSTQTGSRTTGRQRSSHSESS 2184

Query: 2721 G----QHGSTSGQSSTFDQEGSSTGQSSSYGH--RGSGSSQSSGYGRHG-AGSGQSLSH- 2772
                    S +    T  Q GS  GQS S GH  +G+   Q+    RH   G GQS    
Sbjct: 2185 DSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRG 2244

Query: 2773 ----GRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQ 2807
                GR GSG  +SS    H  GS   SG+ Q  +GS Q
Sbjct: 2245 SRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQ 2283



 Score = 1227 bits (3174), Expect = 0.0
 Identities = 949/2424 (39%), Positives = 1206/2424 (49%), Gaps = 291/2424 (12%)

Query: 225  SGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYG 284
            SG       H+    +S          GH SGY     R    S GE H  SSG S    
Sbjct: 97   SGSKKHRRGHRHQEEESETEEDEEDTPGHKSGY-----RHSSWSEGEEHGYSSGHSRGTV 151

Query: 285  Q--HGSGSRQSLGHGRQGSGSRQSPSHVR-HGSGSGHSSSHGQHGSGSSYSYSRGHYESG 341
            +  HGS SR+    G   S   Q  S  R H S  GHS S G+   GSS    R      
Sbjct: 152  KCRHGSNSRRLGRQGNLSSSGNQEGSQKRYHRSSCGHSWSGGKDRHGSSSVELRERINKS 211

Query: 342  SGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYG 401
                     H S S +S    + GSGS     +G HG  S    +SG H S+S QS    
Sbjct: 212  ---------HISPSRESGEEYESGSGSNSWERKG-HGGLSCGLETSG-HESNSTQSRIRE 260

Query: 402  QHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGY 461
            Q           G   SGSG S   G+R    G S SSG      GR  ++         
Sbjct: 261  QK---------LGSSCSGSGDS---GRRSHACGYSNSSG-----CGRPQNAS-------- 295

Query: 462  SSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHG 521
            SS   H      +   Y Q G  SG   G G HG  SG    G  Q  S   S SY Q G
Sbjct: 296  SSCQSHRFGGQGNQFSYIQSGCQSGIKGGQG-HGCVSGGQPSGCGQPESNPCSQSYSQRG 354

Query: 522  SGSRQSLGHSRHGSG---SGQSPSPSRGRHESGSRQSSSYGPHGYGS-GRSSSRGP---- 573
             G+R++ G  ++  G   +G S S   G++ SG  QS S G H YGS GR S+       
Sbjct: 355  YGAREN-GQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEF 413

Query: 574  -----YESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGA 628
                 Y SGS  S+      +   QSSG+ QH   SG   T GQH STS QS    QHG+
Sbjct: 414  SKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQ--TCGQHESTSSQSLGYDQHGS 471

Query: 629  TSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWS--- 685
            +SG++S  GQHGSGS QSS +GQ GSGSGQS   G+HGS  G SS +GQHGS SG S   
Sbjct: 472  SSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGF 531

Query: 686  ---------SSNGPHGSVSGQSSGFG------------HKSGSGQSSGYSQHGSGSSHSS 724
                     SS G HGS S QSSG+G            H  GSGQS+G+ Q+GSGS  SS
Sbjct: 532  GQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSS 591

Query: 725  GYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSS 784
            G+ +HGS SGQSS   QH S SG  SSYGQH SGS QSSG+G+   GS  +    +HGS 
Sbjct: 592  GFGQHGSGSGQSSGFGQHESRSG-QSSYGQHSSGSSQSSGYGQH--GSRQTSGFGQHGSG 648

Query: 785  SGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSG-QGYSQHGSASGHFSSQGR 843
            S  S+  GQ+GSG+  SS  G + SGSGQ+SGFGQHES SG   Y QHG  S   S  G+
Sbjct: 649  SSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQ 708

Query: 844  HGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQS 903
            HGS+SGQ+S  GQH+ SSGQSSS+GQH S S  +SG G+HGSGSGQS G GQ  S SGQS
Sbjct: 709  HGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQS 768

Query: 904  PSYGRHGSGSGRSSSSGRHGSGSGQSSGFG-HKSSSGQSSGYTQHGSGSGHSSSYEQHGS 962
             SYG+H SGS +SS  G+H  GS Q+SGFG H S S QS+G+ Q+GSGSG S+ + QHGS
Sbjct: 769  -SYGQHSSGSSQSSGYGQH--GSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGS 825

Query: 963  RSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSS 1022
             SGQSS   QH S S   SSYGQHGSGS QS G+GQHGS SGQ  +   G+H S SGQ S
Sbjct: 826  GSGQSSGFGQHESRS-HQSSYGQHGSGSSQSSGYGQHGSSSGQ--TSGFGQHRSSSGQYS 882

Query: 1023 SYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGST 1082
             +G + SGSG SS  G + +GSG  SG G  ESRS QSS YGQHGS S  SS +GQHGS+
Sbjct: 883  GFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSS-YGQHGSGSSQSSGYGQHGSS 941

Query: 1083 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG 1142
            SGQ+   GQH + SGQSS  GQHGSGS QSSG+G+  SGSG+S G GQ  S S QS +YG
Sbjct: 942  SGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQS-NYG 1000

Query: 1143 RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQ 1202
            +HGSGS +SS  GQHGS  G+++GFG H SSSGQ S + QHGSGS  SSG+GQHG+ SGQ
Sbjct: 1001 QHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQ 1060

Query: 1203 SSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHG 1262
            SS   ++ S S  SS YGQHGSGS QSSG+G+ GS SG +   G+H  G G SS  GQ+G
Sbjct: 1061 SSGFGQYESRSRQSS-YGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYG 1119

Query: 1263 SGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSST 1322
            SGSG+SS  G + S +G SS F QHE  SG SS Y QHG+GS      GQH S SG +++
Sbjct: 1120 SGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSS-YGQHGTGSSQSSGCGQHESGSGPTTS 1178

Query: 1323 FDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSS--YGQHGS 1380
            F Q  S +   SS G   S S QS+G+G++G+GSGQS   G+  S    S S  +G+  +
Sbjct: 1179 FGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQET 1238

Query: 1381 GSGWSSSSGRHG-SGSGQSSGFG-----HHESSSWQSSGCTQHGSGSGHSSSY------- 1427
              G + ++ RH  SG GQS+  G        SS  ++S    H   S   S +       
Sbjct: 1239 THGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGS 1298

Query: 1428 ----------EQHGSRSGQSSRGERHG-SSSGSSSSYGQHGSGSR--------------- 1461
                       + G+  GQ     RHG S  G S+  G   SG +               
Sbjct: 1299 HYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVHSG 1358

Query: 1462 -------QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYG-SGSGWSSSRGPYESG 1513
                   Q   H Q GS  G+S S    RH +  GQ+   + +G SG G S+ RG   +G
Sbjct: 1359 VSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSRTTG 1418

Query: 1514 SSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC--GQHGASSGQ--- 1568
                 G GH ES   +    G H   S    THGQ GS  G+S S   G+HG + GQ   
Sbjct: 1419 ---RRGSGHSESSDSEVHSGGSHRPQS-QEQTHGQAGSQHGESGSTVHGRHGTTHGQTGD 1474

Query: 1569 SSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSS--SSGQ 1626
            ++ H  +  G S   G          S   G+RGSG  +S     H  GS   S  + GQ
Sbjct: 1475 TTRHAHYHHGKSTQRG----------SSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQ 1524

Query: 1627 HGSGLGESSGFGH--HESSSGQSSSYSQHGSGSGH-------SSGYGQHGSRSGQSSRGE 1677
             GS  GES    H  H  + GQ+   ++H S SGH       S   G+  +   +S+  E
Sbjct: 1525 SGSQHGESESIIHDRHRITHGQTGDTTRH-SYSGHEQTTQTGSRTTGRQRTSHSESTDSE 1583

Query: 1678 RH-GSSSRSSSR---YGQHGSGSRQS--SGHGRQGSGSGQ-SPSRGRHGSGLGHSSSHGQ 1730
             H G S R  SR   YGQ GS   +   + H R G+  GQ   + G   SG G S+  G 
Sbjct: 1584 VHSGGSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGS 1643

Query: 1731 HGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSG-----HFCSQGQHGS 1785
              +G  RSS     +S   HS V   H +G  H  A SQHG         H  + GQ G 
Sbjct: 1644 RTTGRQRSSHSESSDSEV-HSGVSHTH-TGHTHGQAGSQHGQSESIVPERHGTTHGQTGD 1701

Query: 1786 TSGQSSTFDQEGSSTGQSSSHGQHGSGSSQ-SSSYGQQG---SGSGQSPSRGRHGSGSGH 1841
            T+  +       + TG S + G+ GSG S+ S S G  G   + SG +  + R   G   
Sbjct: 1702 TTRHAHYHHGLTTQTG-SRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESE 1760

Query: 1842 SSSYGQHGSGSGWSSSSGRHG-SGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQH 1900
            S  + +HG+  G +  + RH  SG GQS+  G   ++  +SSG++++    GHS      
Sbjct: 1761 SIVHERHGTIHGQTGDTTRHAHSGHGQSTQTG-SRTTGRRSSGHSEYSDSEGHS------ 1813

Query: 1901 GSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQ 1960
            G      SRG  HG  +GS     +     R    HGQ G  SG S S   G   S    
Sbjct: 1814 GFSQRPHSRGHTHG-QAGSQHGESESIVDERHGTTHGQTGDTSGHSQS---GHGQSTQSG 1869

Query: 1961 SSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG 2020
            SS+ G   SG   SS    +  GS   SG  H ++RS       QHG S   S+ H +H 
Sbjct: 1870 SSTTGRRRSGHSESSDSEVHSGGSHTHSGHTHSQARS-------QHGES--ESTVHKRHQ 1920

Query: 2021 SASGQSSSCGQHG-ASSGQ-----SSSHGQHGSGSSQ-SSGYGRQG-SGSGQSPGHGQRG 2072
            +  GQ+    +HG  S GQ     S + G+ GSG S+ S   G  G S +     HGQ G
Sbjct: 1921 TTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAG 1980

Query: 2073 SGSRQSPS--YGRHGSGSGRSSSSGQHG-PGLGESSGFGHHESSSGQSSSYSQHGSGSGH 2129
            S   +S S  + RHG+  G+++ + +HG  G G+S+  G   ++  ++S +S++    GH
Sbjct: 1981 SHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRG-SRTTGRRASGHSEYSDSEGH 2039

Query: 2130 SS--------GYGQHGSRSGQ--SSRGERHGSS---SGSSSRYGQHGSG---SRQSSGHG 2173
            S          +GQ GS+ G+  SS  ERHG++   +G ++R+   G G    R S   G
Sbjct: 2040 SGVSHTHSGHAHGQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAG 2099

Query: 2174 RQGSGSGHSPSRGRHG------SGSGHSSSHGQHG-SGSGRSSSRGPYESRSGHSSVFGQ 2226
            R+GSG   S     H       SG  +  +  QHG SGS     +G    ++G ++  GQ
Sbjct: 2100 RRGSGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQ 2159

Query: 2227 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGS--GSS 2284
              SG G S+      +G      +  H  +S   S    E S T    +H Q GS  G S
Sbjct: 2160 --SGHGQSTQTGSRTTGR----QRSSHSESS--DSEVHSEASPTHSGHTHSQAGSRHGQS 2211

Query: 2285 QSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 2344
             SS +G+QG+  GQ+    RH       + YG   S    S ++GR GSG  +SS    H
Sbjct: 2212 GSSGHGRQGTTHGQTGDTTRH-------AHYGYGQSTQRGSRTTGRRGSGHSESSDSEVH 2264

Query: 2345 ESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSL 2404
               S   SG+ Q  +GS      +Q    S    R E     +G ++ +G  G G     
Sbjct: 2265 SWGSHTHSGHIQGQAGS------QQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQSTQT 2318

Query: 2405 GHGQHGSGSGQSPSPSRGRHGSGS-GQSSSYSPYGSGSGWSSSRGPYESG-SGHSSGLGH 2462
            G     +   QS S  R RHGS    +  SY P             Y+ G +G+    G 
Sbjct: 2319 GSRSSRASHFQSHSSERQRHGSSQVWKHGSYGP-----------AEYDYGHTGYGPSGGS 2367

Query: 2463 RESRSGQSSGYGQHGSSSGHSSTH 2486
            R+S S     +    +++   S H
Sbjct: 2368 RKSISNSHLSWSTDSTANKQLSRH 2391



 Score = 1174 bits (3038), Expect = 0.0
 Identities = 833/2011 (41%), Positives = 1032/2011 (51%), Gaps = 253/2011 (12%)

Query: 1018 SGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS--- 1074
            SG       +R     S +    E   GH SG  H     G+     +HG SSGHS    
Sbjct: 97   SGSKKHRRGHRHQEEESETEEDEEDTPGHKSGYRHSSWSEGE-----EHGYSSGHSRGTV 151

Query: 1075 --THGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 1132
               HG +    G+  +    G   G    + +   G S S G  R GS S +      + 
Sbjct: 152  KCRHGSNSRRLGRQGNLSSSGNQEGSQKRYHRSSCGHSWSGGKDRHGSSSVELRERINKS 211

Query: 1133 --SGSRQSPSYGRHGSGSGRSSSSGQHGSGLG-ESSGFGHHESSSGQSSSYSQHGSGSGH 1189
              S SR+S      GSGS      G  G   G E+SG   HES+S QS    Q    S  
Sbjct: 212  HISPSRESGEEYESGSGSNSWERKGHGGLSCGLETSG---HESNSTQSRIREQKLGSS-- 266

Query: 1190 SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHG 1249
             SG G  G RS         G S+ S     Q+ S S QS   G QG+   +  S  + G
Sbjct: 267  CSGSGDSGRRSHAC------GYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSG 320

Query: 1250 --SGLGHSSSHGQHGSGSGRSSSRGPYESRSGHS----------SVFGQHESGSGHSSAY 1297
               G GH    G   SG G+  S    +S S             +  GQ  +GS  SS  
Sbjct: 321  IKGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCC 380

Query: 1298 SQHGSGSGHFCSQGQH----------GSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSS 1347
             Q+GSG    CS GQH           S+S + S  DQ GS + QS+S+   G+G SQSS
Sbjct: 381  GQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSS 440

Query: 1348 GYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESS 1407
            G+ +H  GSGQ+   G+H S S  S  Y QHGS SG +S  G+HGSGSGQSSGFG   S 
Sbjct: 441  GFEQHVCGSGQTC--GQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSG 498

Query: 1408 SWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHG 1467
            S QSSG  QHGS SG SS + QHGS SGQSS   +H S S   SSYGQHGSGS QS G+G
Sbjct: 499  SGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRS-RQSSYGQHGSGSSQSSGYG 557

Query: 1468 QHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRS 1527
            Q+GS      +   G+HG GSGQS+ +  YGSGSG SS  G + SGS  SSG G  ESRS
Sbjct: 558  QYGSRE----TSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRS 613

Query: 1528 GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGR 1587
            GQSS YGQH S S  SS +GQHGS   Q+S  GQHG+ S QS+  GQ+GSGS QSSG+G+
Sbjct: 614  GQSS-YGQHSSGSSQSSGYGQHGSR--QTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQ 670

Query: 1588 QGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS 1647
              SGSGQS G GQ  S S  S SYG+HG GS +SS  GQHGS  G++SGFG HE SSGQS
Sbjct: 671  HVSGSGQSSGFGQHESRSGHS-SYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQS 729

Query: 1648 SSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGS 1707
            SS+ QHGSGSG SSG+GQHGS SGQSS   +H S S  SS YGQH SGS QSSG+G+ GS
Sbjct: 730  SSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSS-YGQHSSGSSQSSGYGQHGS 788

Query: 1708 GSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAY 1767
               Q+   G+HGSG   S+  GQ+GSGSG+S+  G + S SG SS FGQHES S H S+Y
Sbjct: 789  R--QTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRS-HQSSY 845

Query: 1768 SQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSG 1827
             QHGSGS      GQHGS+SGQ+S F Q  SS+GQ S  GQHGSGS QSS +GQ G+GSG
Sbjct: 846  GQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSG 905

Query: 1828 QSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQH 1887
            Q    G+H S S H SSYGQHGSGS  SS  G+HGS SGQ+ GFG H S S QSSG+ QH
Sbjct: 906  QYSGFGQHESRS-HQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQH 964

Query: 1888 GSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSP 1947
            GSGSG SS + QH S SG+SS   QH S S S S+YGQHGSGS QS G+GQHGS SGQ+ 
Sbjct: 965  GSGSGQSSGFGQHESGSGKSSGFGQHESRS-SQSNYGQHGSGSSQSSGYGQHGSSSGQTT 1023

Query: 1948 SPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHG 2007
                G+H S SGQ S +G +GSGS  SS  G + +GSG SSG G  ESRS QSS YGQHG
Sbjct: 1024 G--FGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSS-YGQHG 1080

Query: 2008 SSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG 2067
            S S  SS +GQHGS SGQ+S  GQH   SGQSS  GQ+GSGS QSSG+G+ GSG+G+S G
Sbjct: 1081 SGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSG 1140

Query: 2068 HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGS 2127
              Q    S QS SYG+HG+GS +SS  GQH  G G ++ FG H S S   SS  QH S S
Sbjct: 1141 FAQHEYRSGQS-SYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDS 1199

Query: 2128 GHSSGYGQHGSRSGQSS---RGERHGSSSGSS---------------SRYGQHGSGSRQS 2169
            G S+G+GQ+GS SGQS+   +GE     SGS+               +R+ Q G G    
Sbjct: 1200 GQSTGFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQ 1259

Query: 2170 SG----------------------------------------------HGRQGSGSGHSP 2183
            +G                                                RQG+  G   
Sbjct: 1260 TGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRG 1319

Query: 2184 SRGRHG-SGSGHSSSHGQHGSGSGRSS-------------SRGPYESRSGHSSVFGQHES 2229
               RHG SG G S+  G   SG  R S             S  P+     HS    QH  
Sbjct: 1320 DTTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGE 1379

Query: 2230 GSG-----HSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGS- 2283
                    H + Y Q G  +GH  S G   ST   S T  + GS   +SS    H  GS 
Sbjct: 1380 SESTVHERHETTYGQTGEATGHGHS-GHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSH 1438

Query: 2284 ---SQSSSYGQQGSGSGQSPS--RGRHGSGSGHSSSYGQHG------SGSGWSSSSGRHG 2332
               SQ  ++GQ GS  G+S S   GRHG+  G +    +H       S    SS++GR G
Sbjct: 1439 RPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRG 1498

Query: 2333 SGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSS----YEQHGSRSGQSSRGERHGSSSG 2388
            SG  +SS    H   S   SG+T   SGS H  S    +++H    GQ+    RH  S  
Sbjct: 1499 SGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGH 1558

Query: 2389 SSSSYGQHGSGSRQSLGHGQ------HGSGS----------GQSPSPSRG-------RHG 2425
              ++     +  RQ   H +      H  GS          GQ+ S           RHG
Sbjct: 1559 EQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTVHERHG 1618

Query: 2426 SGSGQSSSYSPYG-SGSGWSSSRGPYESG---SGHS--------SGLGHRESRSGQSSGY 2473
            +  GQ    + +  SG G S+ RG   +G   S HS        SG+ H  +        
Sbjct: 1619 TTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHGQAG 1678

Query: 2474 GQHGSSSG-----HSSTHGQHGSTSGQSSSCGQHGASSGQSS-SHGQHGSGSSQ---SSG 2524
             QHG S       H +THGQ G T+  +     HG ++   S + G+ GSG S+   S G
Sbjct: 1679 SQHGQSESIVPERHGTTHGQTGDTTRHAHY--HHGLTTQTGSRTTGRRGSGHSEYSDSEG 1736

Query: 2525 Y-GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHG-SGLGESSGFGHHES 2582
            Y G   + SG + G  +   G  +S  + RHG+  G++  + +H  SG G+S+  G   +
Sbjct: 1737 YSGVSHTHSGHTHGQARSQHGESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQTGSR-T 1795

Query: 2583 SSGQSSSYSQHGSGSGHSS----------GYGQHGSRSGQSSR--GERHGSSSGSSSHYG 2630
            +  +SS +S++    GHS            +GQ GS+ G+S     ERHG++ G +    
Sbjct: 1796 TGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQHGESESIVDERHGTTHGQTGDTS 1855

Query: 2631 QHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGH 2690
             H       SGHG Q + SG S + GR  SG   SS    H  GS   S     ++R  H
Sbjct: 1856 GHSQ-----SGHG-QSTQSGSSTT-GRRRSGHSESSDSEVHSGGSHTHSGHTHSQARSQH 1908

Query: 2691 ----SSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGST----SGQSSTFDQEGSS--- 2739
                S+V  +H++  G +   ++HG  S     Q    +T    SG S   D EG S   
Sbjct: 1909 GESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVS 1968

Query: 2740 -TGQSSSYGHRGSG--SSQSSGYGRHGAGSGQSLSHGRHG-SGSGQSSSYGQHGSGSGQS 2795
             T    ++G  GS    S SS + RHG   GQ+    RHG SG GQS+  G   +G  ++
Sbjct: 1969 HTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGR-RA 2027

Query: 2796 SGYSQHGSGSGQDGYSYCKGGSNHDGGSSGS 2826
            SG+S++    G  G S+   G  H  G +GS
Sbjct: 2028 SGHSEYSDSEGHSGVSHTHSGHAH--GQAGS 2056



 Score = 1120 bits (2898), Expect = 0.0
 Identities = 837/2061 (40%), Positives = 1058/2061 (51%), Gaps = 261/2061 (12%)

Query: 123  QESSFSHSSWSAGENDSYSRNVRGSLKP-GTESISRRLSFQRDFSGQHNSYSGQSSSYGE 181
            Q +SF        ++  + ++V GS +  G    +   S   D   QH S SG++S +G+
Sbjct: 425  QSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYD---QHGSSSGKTSGFGQ 481

Query: 182  QNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQS 241
              S S QSSG GQCGSGSGQS  +GQHGS SGQSS    HGS SGQSSGF QH+S S QS
Sbjct: 482  HGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQS 541

Query: 242  SGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGS 301
            S Y QHGSGS  SSGYGQ+GSR  ++S   +H   SG S+ +GQ+GSGS QS G G+ GS
Sbjct: 542  S-YGQHGSGSSQSSGYGQYGSR--ETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGS 598

Query: 302  GSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGY 361
            GS QS    +H S SG SS +GQH SGSS S   G+ + GS QTSGFGQH SGS QS+G+
Sbjct: 599  GSGQSSGFGQHESRSGQSS-YGQHSSGSSQS--SGYGQHGSRQTSGFGQHGSGSSQSTGF 655

Query: 362  SKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSG 421
             ++GSGSG SS  GQH S SGQ+S  GQH S S  SS YGQH   S  SSG GQH S SG
Sbjct: 656  GQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSS-YGQHGFGSSQSSGYGQHGSSSG 714

Query: 422  QSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQH 481
            Q+ G GQ    SGQS S GQHG+G G+SS  G + SGSG SSGFG HES S  SS Y QH
Sbjct: 715  QTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSS-YGQH 773

Query: 482  GSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSP 541
             SGS  SSG+GQHGSR  Q+S   + GS +  S+ +GQ+GSGS QS G  +HGSGSGQS 
Sbjct: 774  SSGSSQSSGYGQHGSR--QTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSS 831

Query: 542  SPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHG 601
                G+HES S QSS YG HG GS +SS  G + S SG +SG G   S SGQ SG+GQHG
Sbjct: 832  G--FGQHESRSHQSS-YGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHG 888

Query: 602  SSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPS 661
            S SG SS  GQHG+ SGQ S  GQH + S Q SS+GQHGSGSSQSS YGQ GS SGQ+  
Sbjct: 889  SGSGQSSGFGQHGTGSGQYSGFGQHESRSHQ-SSYGQHGSGSSQSSGYGQHGSSSGQTFG 947

Query: 662  RGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSS 721
             G+H S  G SS +GQHGSGSG SS  G H S SG+SSGFG        S Y QHGSGSS
Sbjct: 948  FGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSS 1007

Query: 722  HSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRH 781
             SSGY +HGS SGQ++   QH SSSG  S +GQHGSGS QSSG G+ G+GSG S    ++
Sbjct: 1008 QSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQY 1067

Query: 782  GSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQ--GYSQHGSASGHFS 839
             S S   SS+GQHGSG+S SS  G + S SGQ SGFGQH  GSGQ  G+ Q+GS SG  S
Sbjct: 1068 ESRS-RQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSS 1126

Query: 840  SQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSG 899
              G+HGS +G+SS   QH+  SGQ SSYGQH + S  +SG G+H SGSG +   GQ  SG
Sbjct: 1127 GFGQHGSGTGKSSGFAQHEYRSGQ-SSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSG 1185

Query: 900  SGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHG----------- 948
            S    S G+H S SG+S+  G++GSGSGQS+G G   S    SG T HG           
Sbjct: 1186 SDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETTHGQTIN 1245

Query: 949  ------SGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSY----------GQH--GSGS 990
                  SG G S+      +R  +SS+SE   S   S  S+          G H   SGS
Sbjct: 1246 TTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGS 1305

Query: 991  ----RQSLGHGQHGSGSGQSPSPSRGRHG-SGSGQSSSYGPYRSGSGWSS---------- 1035
                RQ   HGQ G  +         RHG SG GQS+  G   SG    S          
Sbjct: 1306 TVRRRQGTTHGQRGDTT---------RHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVH 1356

Query: 1036 ---SRGPYESGSGHS-SGLGHRESRS----GQSSGYGQHGSSSGH------------SST 1075
               S  P+     HS +G  H ES S       + YGQ G ++GH            S T
Sbjct: 1357 SGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSRT 1416

Query: 1076 HGQHGSTSGQSSSCGQHGASS----GQSSSHGQHGS--GSSQSSGYGRQGSGSGQS---- 1125
             G+ GS   +SS    H   S     Q  +HGQ GS  G S S+ +GR G+  GQ+    
Sbjct: 1417 TGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTT 1476

Query: 1126 -PGHGQRG-SGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS--GQSSS-- 1179
               H   G S  R S + GR GSG   SS S  H  G    SG  H +S S  G+S S  
Sbjct: 1477 RHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESII 1536

Query: 1180 -------YSQHGSGSGHSSGYGQHGSRSGQSSRGER---HGSSSGSSSH----------- 1218
                   + Q G  + HS    +  +++G  + G +   H  S+ S  H           
Sbjct: 1537 HDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSRE 1596

Query: 1219 --YGQHGS---------GSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGR 1267
              YGQ GS           R  + HG+ G  +GHS       SG G S+  G   +G  R
Sbjct: 1597 HTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHS------HSGHGQSTQRGSRTTGRQR 1650

Query: 1268 SSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSG-----HFCSQGQHGSTSGQSST 1322
            SS     +S   HS V   H +G  H  A SQHG         H  + GQ G T+  +  
Sbjct: 1651 SSHSESSDSEV-HSGVSHTH-TGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRHAHY 1708

Query: 1323 FDQEGSSTGQSSSYGHRGSGSSQ---SSGY-GRHGAGSGQSPSRGRHGSGSGHSSSYGQH 1378
                 + TG S + G RGSG S+   S GY G     SG +  + R   G   S  + +H
Sbjct: 1709 HHGLTTQTG-SRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERH 1767

Query: 1379 GSGSGWSSSSGRHG-SGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQS 1437
            G+  G +  + RH  SG GQS+  G   ++  +SSG +++    GHS      G      
Sbjct: 1768 GTIHGQTGDTTRHAHSGHGQSTQTG-SRTTGRRSSGHSEYSDSEGHS------GFSQRPH 1820

Query: 1438 SRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPY 1497
            SRG  HG +        QHG    +S+   +HG+  GQ+   S G   SG GQS+     
Sbjct: 1821 SRGHTHGQAG------SQHGES--ESIVDERHGTTHGQTGDTS-GHSQSGHGQSTQ---- 1867

Query: 1498 GSGSGWSSSRGPYESGSSHS---SGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSG 1554
             SGS  +  R    S SS S   SG  H  S    S    QHG S   S+ H +H +T G
Sbjct: 1868 -SGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHTHSQARSQHGES--ESTVHKRHQTTHG 1924

Query: 1555 QSSSCGQHG-ASSGQ-----SSSHGQHGSGSSQ-SSGYGRQG-SGSGQSPGHGQRGSGSR 1606
            Q+    +HG  S GQ     S + G+ GSG S+ S   G  G S +     HGQ GS   
Sbjct: 1925 QTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYP 1984

Query: 1607 QSPS--YGRHGSGSGRSSSSGQHG-SGLGESSGFGHHESSSGQSSSYSQHGSGSGHSS-- 1661
            +S S  + RHG+  G+++ + +HG SG G+S+  G   ++  ++S +S++    GHS   
Sbjct: 1985 ESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRG-SRTTGRRASGHSEYSDSEGHSGVS 2043

Query: 1662 ------GYGQHGSRSGQ--SSRGERHGSSSRSSSRYGQHGSGSRQS-SGHGRQGSGSGQS 1712
                   +GQ GS+ G+  SS  ERHG++      +GQ G  +R + SGHG+  S    S
Sbjct: 2044 HTHSGHAHGQAGSQHGESGSSVHERHGTT------HGQTGDTTRHAHSGHGQ--STQRGS 2095

Query: 1713 PSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGH----SSVFGQHESGSGHSSAYS 1768
             + GR GSG   SS    H   S   S     ++RS H    S++ G+  +  G +   +
Sbjct: 2096 RTAGRRGSGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTT 2155

Query: 1769 QHGSGSGHFCSQGQHGSTSGQ---------SSTFDQEGSSTGQSSSHGQHGS--GSSQSS 1817
            +HG  SGH  S      T+G+          S    E S T    +H Q GS  G S SS
Sbjct: 2156 RHGQ-SGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSS 2214

Query: 1818 SYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESS 1877
             +G+QG+  GQ+    RH       + YG   S    S ++GR GSG  +SS    H   
Sbjct: 2215 GHGRQGTTHGQTGDTTRH-------AHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWG 2267

Query: 1878 SWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHG 1937
            S   SG+ Q  +GS      +Q    S    R E     +G ++ +G  G G     G  
Sbjct: 2268 SHTHSGHIQGQAGS------QQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQSTQTGSR 2321

Query: 1938 QHGSGSGQSPSPSRGRHGSGS-GQSSSYGPYGSGSGWSSSRGPYESG-SGHSSGLGHRES 1995
               +   QS S  R RHGS    +  SYGP             Y+ G +G+    G R+S
Sbjct: 2322 SSRASHFQSHSSERQRHGSSQVWKHGSYGP-----------AEYDYGHTGYGPSGGSRKS 2370

Query: 1996 RSGQSSGYGQHGSSSGHSSTH 2016
             S     +    +++   S H
Sbjct: 2371 ISNSHLSWSTDSTANKQLSRH 2391



 Score = 1104 bits (2855), Expect = 0.0
 Identities = 779/1776 (43%), Positives = 948/1776 (53%), Gaps = 201/1776 (11%)

Query: 1212 SSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSS-SHGQ-HGSGSGRSS 1269
            +SGS  H   H     +S     +    GH        SG  HSS S G+ HG  SG S 
Sbjct: 96   ASGSKKHRRGHRHQEEESETEEDEEDTPGHK-------SGYRHSSWSEGEEHGYSSGHS- 147

Query: 1270 SRGPYESRSGHSSV-FGQH----ESGSGHSSAYSQHGSGSGHFCSQGQ--HGSTSGQSST 1322
             RG  + R G +S   G+      SG+   S    H S  GH  S G+  HGS+S +   
Sbjct: 148  -RGTVKCRHGSNSRRLGRQGNLSSSGNQEGSQKRYHRSSCGHSWSGGKDRHGSSSVELRE 206

Query: 1323 FDQEG--SSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQH-G 1379
               +   S + +S      GSGS+     G  G   G   S   H S S  S    Q  G
Sbjct: 207  RINKSHISPSRESGEEYESGSGSNSWERKGHGGLSCGLETSG--HESNSTQSRIREQKLG 264

Query: 1380 SGSGWSSSSGR--HGSGSGQSSGFGHHESSSWQSSGCTQHG-SGSGHSSSYEQHGSRSGQ 1436
            S    S  SGR  H  G   SSG G  +++S   S C  H   G G+  SY Q G +SG 
Sbjct: 265  SSCSGSGDSGRRSHACGYSNSSGCGRPQNAS---SSCQSHRFGGQGNQFSYIQSGCQSGI 321

Query: 1437 SSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR--GRHGSGSGQSSSY 1494
               G+ HG  SG   S       +  S  + Q G G+ ++  P    G+  +GS QSS  
Sbjct: 322  KG-GQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCC 380

Query: 1495 SPYGSGSGWSSSRGPYESGS----SHSSGLGHRE------SRSGQSSGYGQHGSSSGHSS 1544
              YGSG   S S G +E GS    S+SS            S S QS+ + QHG+    SS
Sbjct: 381  GQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSS 440

Query: 1545 THGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSG 1604
               QH   SGQ+  CGQH ++S QS  + QHGS S ++SG+G+ GSGSGQS G GQ GSG
Sbjct: 441  GFEQHVCGSGQT--CGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSG 498

Query: 1605 SRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYG 1664
            S QS  +G+HGS SG+SS  GQHGS  G+SSGFG HES S QSS Y QHGSGS  SSGYG
Sbjct: 499  SGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSS-YGQHGSGSSQSSGYG 557

Query: 1665 QHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGH 1724
            Q+GSR  ++S   +HG  S  S+ +GQ+GSGS QSSG G+ GSGSGQS   G+H S  G 
Sbjct: 558  QYGSR--ETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQ 615

Query: 1725 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHG 1784
            SS +GQH SGS +SS  G + SR   +S FGQH SGS  S+ + Q+GSGSG     GQH 
Sbjct: 616  SS-YGQHSSGSSQSSGYGQHGSRQ--TSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHV 672

Query: 1785 STSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSS 1844
            S SGQSS F Q  S +G SS +GQHG GSSQSS YGQ GS SGQ+   G+H   SG SSS
Sbjct: 673  SGSGQSSGFGQHESRSGHSS-YGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSS 731

Query: 1845 YGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRS 1904
            +GQHGSGSG SS  G+HGSGSGQSSGFG HES S QSS Y QH SGS  SS Y QHGSR 
Sbjct: 732  FGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSS-YGQHSSGSSQSSGYGQHGSR- 789

Query: 1905 GQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY 1964
             Q+S   QHGS S  S+ +GQ+GSGS QS G GQHGSGSGQS     G+H S S QSS Y
Sbjct: 790  -QTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSG--FGQHESRSHQSS-Y 845

Query: 1965 GPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASG 2024
            G +GSGS  SS  G + S SG +SG G   S SGQ SG+GQHGS SG SS  GQHG+ SG
Sbjct: 846  GQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSG 905

Query: 2025 QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 2084
            Q S  GQH + S Q SS+GQHGSGSSQSSGYG+ GS SGQ+ G GQ  SGS QS  +G+H
Sbjct: 906  QYSGFGQHESRSHQ-SSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQH 964

Query: 2085 GSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 2144
            GSGSG+SS  GQH  G G+SSGFG HES S Q S+Y QHGSGS  SSGYGQHGS SGQ++
Sbjct: 965  GSGSGQSSGFGQHESGSGKSSGFGQHESRSSQ-SNYGQHGSGSSQSSGYGQHGSSSGQTT 1023

Query: 2145 RGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSG 2204
               +H SSSG  S +GQHGSGS QSSG G+ G+GSG S   G++ S S   SS+GQHGSG
Sbjct: 1024 GFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRS-RQSSYGQHGSG 1082

Query: 2205 SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD 2264
            S +SS  G + S SG +S FGQH  GSG SS + Q+GSGSG     GQHGS +G+SS F 
Sbjct: 1083 SSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFA 1142

Query: 2265 QEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGW 2324
            Q    +GQ SS+GQHG+GSSQSS  GQ  SGSG + S G+H SGS + SS GQH S SG 
Sbjct: 1143 QHEYRSGQ-SSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQ 1201

Query: 2325 SSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHG----------SGSGHSSSYEQHGSRS 2374
            S+  G++GSGSGQS+G G  ES   + SG T HG          + + HS S +   +++
Sbjct: 1202 STGFGQYGSGSGQSTGLGQGESQQVE-SGSTVHGRQETTHGQTINTTRHSQSGQGQSTQT 1260

Query: 2375 GQSSRGERHGSSSGSSSSYGQHGSGSRQSLG-HGQHGSGSGQSPSPSRGRHGSGSGQSSS 2433
            G      R  S S +S S        R S   H Q GS   +S S  R R G+  GQ   
Sbjct: 1261 GSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGD 1320

Query: 2434 YSPYG-SGSGWSSSRGPYESGS---GHS--------SGLGHRESRSGQ--SSGYGQHGSS 2479
             + +G SG G S+  G   SG     HS        SG+ HR     Q  S    QHG S
Sbjct: 1321 TTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGES 1380

Query: 2480 SGHSSTHGQHGSTSGQSSSCGQHGASS-GQSSSH-----GQHGSGSSQSSGYGRQGSGS- 2532
               S+ H +H +T GQ+     HG S  GQS+       G+ GSG S+SS       GS 
Sbjct: 1381 --ESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSH 1438

Query: 2533 ---GQSPGHGQRGS--GSRQSPSYGRHGSGSGR-------------------SSSSGQHG 2568
                Q   HGQ GS  G   S  +GRHG+  G+                   SS++G+ G
Sbjct: 1439 RPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRG 1498

Query: 2569 SGLGES------SGFGHHESSSGQSSSYSQHGSGSG-----HSSGYGQHGSRSGQSSRGE 2617
            SG  ES      SG  H  S      S SQHG         H   +GQ G  +  S  G 
Sbjct: 1499 SGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGH 1558

Query: 2618 RHGSSSGS-------SSH----------------------YGQHGSGSRQS--SGHGRQG 2646
               + +GS       +SH                      YGQ GS   +   + H R G
Sbjct: 1559 EQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTVHERHG 1618

Query: 2647 SGSGQ-SPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSS 2705
            +  GQ   + G   SG G S+  G   +G  RSS     +S + HS V   H +G  H  
Sbjct: 1619 TTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHSESSDSEV-HSGVSHTH-TGHTHGQ 1676

Query: 2706 AYSQHGSGSG-----HFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSS--- 2757
            A SQHG         H  + GQ G T+  +       + TG S + G RGSG S+ S   
Sbjct: 1677 AGSQHGQSESIVPERHGTTHGQTGDTTRHAHYHHGLTTQTG-SRTTGRRGSGHSEYSDSE 1735

Query: 2758 --------------GYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHG-SGSGQ-------- 2794
                          G  R   G  +S+ H RHG+  GQ+    +H  SG GQ        
Sbjct: 1736 GYSGVSHTHSGHTHGQARSQHGESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQTGSRT 1795

Query: 2795 ----SSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGS 2826
                SSG+S++    G  G+S       H  G +GS
Sbjct: 1796 TGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGS 1831



 Score =  679 bits (1753), Expect = 0.0
 Identities = 438/916 (47%), Positives = 516/916 (56%), Gaps = 88/916 (9%)

Query: 1981 ESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS-----THGQHGSASGQSSSCGQHGAS 2035
            E   GH SG  H     G+     +HG SSGHS       HG +    G+  +    G  
Sbjct: 120  EDTPGHKSGYRHSSWSEGE-----EHGYSSGHSRGTVKCRHGSNSRRLGRQGNLSSSGNQ 174

Query: 2036 SGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG--SGSRQSPSYGRHGSGSGRSSS 2093
             G    + +   G S S G  R GS S +      +   S SR+S      GSGS     
Sbjct: 175  EGSQKRYHRSSCGHSWSGGKDRHGSSSVELRERINKSHISPSRESGEEYESGSGSNSWER 234

Query: 2094 SGQHGPGLG-ESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSS 2152
             G  G   G E+SG   HES+S QS    Q    S   SG G  G RS         G S
Sbjct: 235  KGHGGLSCGLETSG---HESNSTQSRIREQKLGSS--CSGSGDSGRRSHAC------GYS 283

Query: 2153 SGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHG--SGSGHSSSHGQHGSGSGRSSS 2210
            + S     Q+ S S QS   G QG+   +  S  + G   G GH    G   SG G+  S
Sbjct: 284  NSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQPES 343

Query: 2211 RGPYESRSGHS----------SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQH------- 2253
                +S S             +  GQ  +GS  SS   Q+GSG    CS GQH       
Sbjct: 344  NPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGR 403

Query: 2254 ---GSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSG 2310
                S+S + S  DQ GS + QS+S  QHG+G SQSS + Q   GSGQ+   G+H S S 
Sbjct: 404  FSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTC--GQHESTSS 461

Query: 2311 HSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQH 2370
             S  Y QHGS SG +S  G+HGSGSGQSSGFG   S S QSSG+ QHGS SG SS + QH
Sbjct: 462  QSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQH 521

Query: 2371 GSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQ 2430
            GS SGQSS   +H S S   SSYGQHGSGS QS G+GQ+GS      +   G+HG GSGQ
Sbjct: 522  GSVSGQSSGFGQHESRS-RQSSYGQHGSGSSQSSGYGQYGSRE----TSGFGQHGLGSGQ 576

Query: 2431 SSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG 2490
            S+ +  YGSGSG SS  G + SGSG SSG G  ESRSGQSS YGQH S S  SS +GQHG
Sbjct: 577  STGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSS-YGQHSSGSSQSSGYGQHG 635

Query: 2491 STSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPS 2550
            S   Q+S  GQHG+ S QS+  GQ+GSGS QSSG+G+  SGSGQS G GQ  S S  S S
Sbjct: 636  SR--QTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHS-S 692

Query: 2551 YGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS 2610
            YG+HG GS +SS  GQHGS  G++SGFG HE SSGQSSS+ QHGSGSG SSG+GQHGS S
Sbjct: 693  YGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGS 752

Query: 2611 GQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGS-----------GSGQSPSRGRHG 2659
            GQSS   +H S SG SS YGQH SGS QSSG+G+ GS           GS QS   G++G
Sbjct: 753  GQSSGFGQHESRSGQSS-YGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYG 811

Query: 2660 SGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCS 2719
            SG G S+  GQHGSGSG+SS  G +ESR  H S +GQH SGS  SS Y QHGS SG    
Sbjct: 812  SGSGQSAGFGQHGSGSGQSSGFGQHESR-SHQSSYGQHGSGSSQSSGYGQHGSSSGQTSG 870

Query: 2720 QGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGA----------GSGQS 2769
             GQH S+SGQ S F Q GS +GQSS +G  G+GS Q SG+G+H +          GSG S
Sbjct: 871  FGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSS 930

Query: 2770 LS--HGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGS-SGS 2826
             S  +G+HGS SGQ+  +GQH SGSGQSSG+ QHGSGSGQ       G   H+ GS   S
Sbjct: 931  QSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQS-----SGFGQHESGSGKSS 985

Query: 2827 YFLSFPSSTSPYEYVQ 2842
             F    S +S   Y Q
Sbjct: 986  GFGQHESRSSQSNYGQ 1001


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score =  903 bits (2333), Expect = 0.0
 Identities = 998/3150 (31%), Positives = 1285/3150 (40%), Gaps = 411/3150 (13%)

Query: 1    MPKLLQGVITVIDVFYQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQS 60
            M  LL+ +  +I++F QY+ +    DTL+K ELKELLE EF QILKNP+DPD VD+ +  
Sbjct: 1    MSTLLENIFAIINLFKQYSKKDKNTDTLSKKELKELLEKEFRQILKNPDDPDMVDVFMDH 60

Query: 61   LDRDHNKKVDFTEYLLMIFKLVQARNKIIGKDYCQVSGSKLRDDTH--QHQEEQEETEKE 118
            LD DHNKK+DFTE+LLM+FKL QA  +   K+   +SG K R  +H  +H++ ++E  KE
Sbjct: 61   LDIDHNKKIDFTEFLLMVFKLAQAYYESTRKENLPISGHKHRKHSHHDKHEDNKQEENKE 120

Query: 119  ENKRQESSFSHSSWSAGENDSYS-RNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSS 177
              KR  S    ++    +  S S R   G     +     R  +      +    +  +S
Sbjct: 121  NRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNS 180

Query: 178  SYGEQNSDSHQSSG------------RGQCGSGSGQSPNYG---QHGSGSG--------Q 214
            S  E+N   +   G            +     G     N G   Q    SG        Q
Sbjct: 181  SKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQ 240

Query: 215  SSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHG-SRSGQSSRGERH 273
              + DT  S   ++  + + +SS G+SS           S    Q   +R  + SR  + 
Sbjct: 241  DEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQD 300

Query: 274  RSSSGSSSSYGQH-GSGSRQSLGHGRQGS--GSRQSPSHVRHGSGSGHSS-SHGQHGSGS 329
            R S G S    +H GS SR   G   + S  GSR   SH    +  GHS+ S  Q G+  
Sbjct: 301  RDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRH 360

Query: 330  SYSYSRGHYESGSGQ--TSGFGQHESGSGQSSGYSKH-----GSGSGHSSSQGQHGSTSG 382
            + + SRG   S   Q  +S   +H SG  QS+  S+H     G  S   S +G  GS+  
Sbjct: 361  AETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGS 420

Query: 383  QASSSGQHGSSSRQSSSYG---------QHESASRHSSGRGQHSSGSG---------QSP 424
            QAS S  H  +S   S  G          H+ ++R  SG     SGS             
Sbjct: 421  QASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDS 480

Query: 425  GHGQRGSGSG--------QSPSSGQHGTG-FGRSSSSGPYVSGSGYSSGFGHHESS---S 472
             HG+ G+ +G        Q+  S +H     G+ +  G   S  G   G  HHE S   S
Sbjct: 481  AHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQG-SHHEQSVNRS 539

Query: 473  EHSSGYTQHGSGSGHS-SGHGQHGSRSG--QSSRGERQGSSAGSSSSYGQHGSGSRQSLG 529
             HS  +  H +  G S + HGQ GSRS   Q+   E+ G     S S     S    S  
Sbjct: 540  GHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSR 599

Query: 530  HSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGR---SSSRGPYESGSGHS-SGLG 585
            HS+ G G    P  SR +  S S+ S S G H   S R   S+SR  + S    S  G  
Sbjct: 600  HSQVGQGQSSGPRTSRNQGSSVSQDSDSQG-HSEDSERWSGSASRNHHGSAQEQSRDGSR 658

Query: 586  HQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQ 645
            H  S     +G+G    SS  S T     S+SGQ++S  +   +S       +H   S+ 
Sbjct: 659  HPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSAD 718

Query: 646  SSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKS 705
            SSR+   G+G GQ+ S  R   D GH  S G   + S   S +    SVSG     GH  
Sbjct: 719  SSRH--SGTGHGQASSAVR---DSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQA-GHHQ 772

Query: 706  GSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSE-QHGSSSGL--SSSYGQHGSGSHQS 762
             S Q S   + G  S  S  +    S   QS  S    G S+G+   S + Q    S  S
Sbjct: 773  QSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHS 832

Query: 763  SGHGRQGSGSGH--SPSRVRHGS-------SSGHSSSHGQHGSGTSCSSSCGHYESGSGQ 813
            +    Q +  GH  S  R R GS        SGHS SH  H +     S     +SGS  
Sbjct: 833  ASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQG-RSDASRGQSGSRS 891

Query: 814  ASGFGQHE----SGSGQGYSQHGSASGHFS----SQGRHGSTSGQSSSSGQHDSSSGQSS 865
            AS   ++E     GS    S+H  AS H      SQ   G + G  +S  Q  S S  S 
Sbjct: 892  ASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSD 951

Query: 866  SYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRH-GS 924
            S G  E +   +    R+  GS Q     Q   GS    S+    +G G S+ S R  G+
Sbjct: 952  SEGHSEDSERWSGSASRNHRGSAQE----QSRHGSRHPRSHHEDRAGHGHSADSSRQSGT 1007

Query: 925  GSGQSSGFGHKSSS---GQSSGYTQHGSGSGHSSSYEQHGS----RSGQSSRSEQHGSSS 977
               ++S  G  +SS    +SS   +HGS    S+   +H      ++  + R   H  SS
Sbjct: 1008 PHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSS 1067

Query: 978  GS--SSSYGQHGSGSRQSL-GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWS 1034
            GS  S S G       QS+ GHGQ G         +R   G  SG+S S+    S    S
Sbjct: 1068 GSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQS 1127

Query: 1035 -SSRGPYESGSGHSSGLGHRESR---------SGQSSGYGQHGSSSG--HSSTHGQHGST 1082
             S+ G   + +G   G  H ++R          GQ +     GS  G    S H Q    
Sbjct: 1128 ESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDR 1187

Query: 1083 SGQSSSCGQHGASSGQS-SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSY 1141
            SG S S   H  S G+S +SHGQ GS S+           S Q+    Q G GSR S S 
Sbjct: 1188 SGHSGSHHSHTTSQGRSDASHGQSGSRSA-----------SRQTRKDKQSGDGSRHSGS- 1235

Query: 1142 GRHGSGSGRSSSSGQHGSGLGESSG---FGHHESSSGQSSSYSQHGSGSGHSSG---YGQ 1195
             RH   +  + SS     G  +SSG     H  SS  Q S   +H   S   SG      
Sbjct: 1236 -RHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNH 1294

Query: 1196 HGSRSGQSSRGERH-GSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPS---RGRHGSG 1251
            HGS   QS  G RH G      + +G     SRQS  H  + S  G + S   + R   G
Sbjct: 1295 HGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPG 1354

Query: 1252 LGHSSSHGQHGSGSGRSSSRGPYESR-----SGHSSVFGQHESGS-GHS-----SAYSQH 1300
              H S H Q  + S R S  G  ++      SGH    G   + S GHS      + S H
Sbjct: 1355 ERHGSRH-QQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAH 1413

Query: 1301 GSGSGHFCS-----QGQHGSTSGQSSTF-------DQEGSSTGQS--SSYGHRGSGSSQS 1346
            G    H  S     +GQ G +SG+S +F       +Q  S+ GQ+  S+ G +GS   Q+
Sbjct: 1414 GQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQA 1473

Query: 1347 SGYGRHGAG-SGQSPSRGRHGS------GSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSS 1399
                RH A   GQ   RG  GS      GS H  S  + G  SG+  S       S  S 
Sbjct: 1474 RNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGH-SGYHHSHTTPQGRSDASH 1532

Query: 1400 GFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGER--HGSSSGSSSSYGQHG 1457
            G     S+S Q+    Q G GS HS S     S    SSR  +   G S+GS +S  Q  
Sbjct: 1533 GQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGS 1592

Query: 1458 SGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHS 1517
            S S+     G       +S S SR  +GS   QS   S          +   + + SS  
Sbjct: 1593 SVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQ 1652

Query: 1518 SGLGHRESRSGQSSGYGQHGSSSGHSSTHG---QHGSTSGQSSSCGQHGASS--GQSSSH 1572
            SG  H E+ SG  +   Q  + S     HG   Q  + S   S  G+   SS  G S + 
Sbjct: 1653 SGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNR 1712

Query: 1573 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRG--SGSRQSPSYGRHGSGSGRS--------- 1621
            G  GS +S S G+  +      S  HGQ G    S Q  + G+ G  SGRS         
Sbjct: 1713 GSSGSQASDSEGHSEESDTQSVS-AHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVST 1771

Query: 1622 -----SSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS--GH--SSGYGQHGSRSGQ 1672
                 S+ G+ G   G      H ++      S SQ G  +  GH  SS  G+ GS   Q
Sbjct: 1772 HEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQ 1831

Query: 1673 SSRGERHG--------SSSRSSSRYGQHGSG--SRQSSGHGRQGSGSGQSPSRGRHGSGL 1722
            S     H         S  RS    GQ GS   SRQ+    + G GS  S SR    S  
Sbjct: 1832 SVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSR 1891

Query: 1723 GHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS------GH 1776
              SS H Q G G     S GP  SR+  SSV  Q     GHS   S+  SGS      G 
Sbjct: 1892 ADSSRHSQVGQG----QSSGPRTSRNQGSSV-SQDSDSQGHSED-SERWSGSASRNHLGS 1945

Query: 1777 FCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHG 1836
               Q + GS    S   D+ G      SS  Q G+  ++SSS GQ  S   Q+ S     
Sbjct: 1946 AWEQSRDGSRHPGSHHEDRAGHGHSADSSR-QSGTRHTESSSRGQAASSHEQARSSAGER 2004

Query: 1837 SGSGH---SSSYGQH-GSGSGWSSS----SGRHG-SGSGQSSGFGHHESSSWQSSGYTQH 1887
             GS H   S+   +H G G G +SS    SG  G SGS  S   GH E S  QS   +  
Sbjct: 2005 HGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQS--VSAQ 2062

Query: 1888 GSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSP 1947
            G    H  S++       +S+RG Q G SSG S      GS   Q   H Q  S  GQS 
Sbjct: 2063 GKAGPHQQSHK-------ESARG-QSGESSGRS------GSFLYQVSTHEQSESTHGQSA 2108

Query: 1948 SPSRGRHGSGSGQSSSYGPY-GSGSGWSSSRGPYESGSGHSSGLGHRES--RSGQSSGYG 2004
              + GR GS   Q+     +  S  G  + RG      G   G    +S  RSG S  + 
Sbjct: 2109 PSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHH 2168

Query: 2005 QHGSSSGHS-STHGQHG--SASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG 2061
             H +S G S ++ GQ G  SAS ++    Q G  S  S SH    S  + SS +   G G
Sbjct: 2169 SHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQG 2228

Query: 2062 SGQSP-----------------GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGES 2104
                P                 GH +       S S   HGS   +S    +H     E 
Sbjct: 2229 QSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHED 2288

Query: 2105 -SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGS---SSGSSSRYG 2160
             +G GH   SS QS ++    S  G ++          +SS GERHGS    S  SSR+ 
Sbjct: 2289 RAGHGHSAESSRQSGTHHAENSSGGQAAS----SHEQARSSAGERHGSHHQQSADSSRHS 2344

Query: 2161 QHGSGSRQS----SGHGRQGSGSGHSPSRGRHGSGSGHS-SSHGQHG--SGSGRSSSRGP 2213
              G G   S    SGH R  SGS  S S G        S S+HGQ G    S + S+RG 
Sbjct: 2345 GIGHGQASSAVRDSGH-RGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGR 2403

Query: 2214 YESRSGHSSVF----GQHE------------SGSGHSSAYSQHGSGSGHFCSQ------- 2250
               RSG S  F      HE            +G    S + Q    S H  SQ       
Sbjct: 2404 SAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIH 2463

Query: 2251 GQHGSTSG--QSSTFDQEGSSTGQSSSHGQHGSGSSQS-SSYGQQGSGSGQSPSRGRHGS 2307
            G  GS+SG  Q S ++Q    +G S SH  H +   +S +S+G  GS S    +R    S
Sbjct: 2464 GHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQS 2523

Query: 2308 GSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSY 2367
            G G   S  +H   S  + SSG    G GQS   G   S +W SS ++Q     GHS   
Sbjct: 2524 GDGSRHSGSRHHEASSRADSSGHSQVGQGQSE--GPRTSRNWGSS-FSQDSDSQGHSEDS 2580

Query: 2368 EQ---------HGSRSGQSSRGERHGSS--------SGSSSSYGQHGSGSRQSLGHGQHG 2410
            E+         HGS   Q   G RH  S          S+ S  Q G+   Q+   GQ  
Sbjct: 2581 ERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAA 2640

Query: 2411 SGSGQSPSPSRGRHGSGSGQSSSYSPY-GSGSGWSSS-------RGPYESGSGHSSGLGH 2462
            S   Q+ S +  RHGS   QS+  S + G G G +SS       RG   SGS  S   GH
Sbjct: 2641 SSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRG--YSGSQASDNEGH 2698

Query: 2463 RESRSGQS-SGYGQHGS--SSGHSSTHGQHGSTSGQSSSCGQHGASSGQS-SSHGQHGSG 2518
             E    QS S +GQ GS   S   S  G+ G TSG S S     ++  QS SSHG  G  
Sbjct: 2699 SEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTG-- 2756

Query: 2519 SSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFG 2578
                S  GRQGS       H Q    SR S       S  G+ +  G  GS  G   G+ 
Sbjct: 2757 ---PSTRGRQGS------RHEQAQDSSRHS------ASQDGQDTIRGHPGSSRGGRQGYH 2801

Query: 2579 HHES--SSGQSSSYSQHGSGSGHS-SGYGQHGSRSG--------QSSRGERHGSSSGSSS 2627
            H  S  SSG S S+  H +  G S +  GQ GSRS         QS  G RH   SGS  
Sbjct: 2802 HEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRH---SGSRH 2858

Query: 2628 HYGQ-HGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYES 2686
            H    H   SR S     Q  GS +S    R GS +   S    H   S R S      S
Sbjct: 2859 HEASTHADISRHSQAVQGQSEGSRRS---RRQGSSVSQDSDSEGHSEDSERWSGSA---S 2912

Query: 2687 RLGHSSVFGQHESGSGHSSAYSQHGSGSGHFC-SQGQHGSTSGQSSTFDQEGSSTGQS-S 2744
            R  H S   Q   GS H  ++ +  +G GH   S  Q G+   Q+S+  Q  SS  Q+ S
Sbjct: 2913 RNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARS 2972

Query: 2745 SYGHR-GSGSSQSSGYGRH-GAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSS---GYS 2799
            S G R GS   QS+   RH G G GQ+ S  R     G S S      G  + S     S
Sbjct: 2973 SAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVS 3032

Query: 2800 QHG-SGSGQDGY-SYCKGGSNHDGGSSGSY 2827
             HG +GS Q  +    +G S    G SGS+
Sbjct: 3033 AHGQAGSHQQSHQESARGRSGETSGHSGSF 3062



 Score =  820 bits (2119), Expect = 0.0
 Identities = 1007/3251 (30%), Positives = 1298/3251 (39%), Gaps = 571/3251 (17%)

Query: 85   RNKIIGKDYCQVSGSKLRD-----DTHQH-QEEQEETE-KEENKRQESSFSHSSWSAGEN 137
            RN+   +D  + SGS+  +     D  +H Q  Q ++E    ++RQ SS S  S S G +
Sbjct: 897  RNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHS 956

Query: 138  D-------SYSRNVRGSLKPGTESISRR-LSFQRDFSGQ-HNSYSGQSSS--YGEQNSDS 186
            +       S SRN RGS +  +   SR   S   D +G  H++ S + S   + E +S  
Sbjct: 957  EDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGG 1016

Query: 187  HQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQ 246
              +S   Q  S  G+     +HGS   QS+ +  H SG  +    S  + S    S  SQ
Sbjct: 1017 QAASSHEQARSSPGE-----RHGSRHQQSADSSRH-SGIPRRQASSAVRDSGHWGSSGSQ 1070

Query: 247  HGSGSGHS--------SGYGQHG--SRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSL-- 294
                 GHS        SG+GQ G   +S Q S  +     SG S S+    S   QS   
Sbjct: 1071 ASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESA 1130

Query: 295  -GHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHES 353
             G  R  +G RQ   H +    S HS+S  Q G  +     R H   GS +    G H  
Sbjct: 1131 HGRTRTSTGRRQGSHHEQARDSSRHSAS--QEGQDTI----RAH--PGSRRGGRQGSHHE 1182

Query: 354  GSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGR 413
             S   SG+S  GS   H++SQG+  ++ GQ+ S     S+SRQ+    Q    SRHS  R
Sbjct: 1183 QSVDRSGHS--GSHHSHTTSQGRSDASHGQSGSR----SASRQTRKDKQSGDGSRHSGSR 1236

Query: 414  GQHSSGSGQSPGHGQRGSGSGQSPSSGQH-GTGFGRSSSSGPYVSGSGYSSGFGHHESSS 472
               ++    S  H Q G        + +H G+   + S S  +   S   SG     S +
Sbjct: 1237 HHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSA---SRN 1293

Query: 473  EHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQ-GSSAGSSSSYGQ------------ 519
             H S   Q   GS H   H +  +  G S+   RQ G+    SSS+GQ            
Sbjct: 1294 HHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSP 1353

Query: 520  ---HGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES 576
               HGS  +QS   SRH SG G   + S  R +SG R SS  G     S   S     +S
Sbjct: 1354 GERHGSRHQQSADSSRH-SGIGHRQASSAVR-DSGHRGSS--GSQVTNSEGHSEDSDTQS 1409

Query: 577  GSGHSSGLGHQESRSGQSSGYGQHGSSSGHS-------STHGQHGSTSGQS--SSCGQHG 627
             S H     HQ+S   + S  GQ G SSG S       S+H Q  ST GQ+  S+ G+ G
Sbjct: 1410 VSAHGQAGPHQQSH--KESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQG 1467

Query: 628  ATSGQSSSHGQHGS---------GSSQSSRYGQQGSGSGQSPSRGRHGSDFGHS------ 672
            +   Q+ +  +H +         G   SSR G+QGS   QS  R  H S + HS      
Sbjct: 1468 SRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGH-SGYHHSHTTPQG 1526

Query: 673  ---SSYGQHGSGSGWSSSNGPHGSVSG-QSSGFGHKSGSGQ--SSGYSQHGSG-SSHSSG 725
               +S+GQ G  S    +     S  G + SG  H   S +  SS +SQ G G S+ S  
Sbjct: 1527 RSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKT 1586

Query: 726  YRKHGSRSGQSSRSEQHGSSS---GLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHG 782
             R+ GS   Q   SE H   S     S+S   +GS   QS  HG +   S H   R  HG
Sbjct: 1587 SRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSR-HGSRNPRS-HQEDRASHG 1644

Query: 783  SSSGHS----SSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESG-----SGQGYSQHGS 833
             S+  S    + H +  SG   +SS     S  G+  G    +S      SG G  Q  S
Sbjct: 1645 HSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSS 1704

Query: 834  ASGHFSSQGRHGSTSGQSSSSGQHDSSSGQS-SSYGQH--ESASHHASGRGRHGSGSGQS 890
              G   ++G  GS +  S S G  + S  QS S++GQ      SH  S RG+ G  SG+S
Sbjct: 1705 VVGDSGNRGSSGSQA--SDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRS 1762

Query: 891  PGHGQRGSGSGQSPS-YGRHGSGSG--------RSSSSGRHG-SGSGQSSGFGHKSSSG- 939
                 + S   QS S +GR G  +G        ++  S RH  S  GQ +  GH  SS  
Sbjct: 1763 GSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRG 1822

Query: 940  --QSSGYTQHGSGSGHSSSYEQH--------------GSRS--GQSSRSEQHGSSSGSSS 981
              Q S Y Q    SGHS S+  H              GSRS   Q+   +Q G  S  S 
Sbjct: 1823 GRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSG 1882

Query: 982  SYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYE 1041
            S     S    S  H Q G G    P  SR +  S S  S S G       WS S     
Sbjct: 1883 SRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNH 1942

Query: 1042 SGSGHSS---GLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQ 1098
             GS       G  H  S     +G+G    SS  S T     S+ GQ++S  +   SS  
Sbjct: 1943 LGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSA- 2001

Query: 1099 SSSHGQH----GSGSSQSSGYGRQGSGSGQSPGHGQRG-SGSRQSPSYGRHGSGSGRSSS 1153
               HG H     + SS+ SG G  G  S      G RG SGS+ S S G H   S   S 
Sbjct: 2002 GERHGSHHQLQSADSSRHSGIGH-GQASSAVRDSGHRGYSGSQASDSEG-HSEDSDTQSV 2059

Query: 1154 SGQHGSGLGESSGFGHHESSSGQSSSYS-QHGSGSGHSSGYGQHGSRSGQS--SRGERHG 1210
            S Q  +G  + S   H ES+ GQS   S + GS     S + Q  S  GQS  S G R G
Sbjct: 2060 SAQGKAGPHQQS---HKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQG 2116

Query: 1211 SSSGSSSHYGQHGSGSRQSSGHGRQGSGSGH-SPSRG-RHGSGL-------GHSSSHGQH 1261
            S      HY Q    SR S+    Q +  GH  PSRG R GS         GHS SH  H
Sbjct: 2117 S------HYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSH 2170

Query: 1262 GSGSGRS-SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQS 1320
             +  GRS +SRG   SRS     + + +SG G   + S H   S    S        GQS
Sbjct: 2171 TTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQS 2230

Query: 1321 S---TFDQEGSSTGQSS-SYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYG 1376
            S   T    GSS  Q S S GH      +S    R+  GS Q  SR     GS H  S+ 
Sbjct: 2231 SGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSR----DGSRHPRSHH 2286

Query: 1377 QHGSGSGWSSSSGRH-GSGSGQSSGFGHHESSSWQ--SSGCTQHGSGSGHSSSYEQH-GS 1432
            +  +G G S+ S R  G+   ++S  G   SS  Q  SS   +HGS    S+   +H G 
Sbjct: 2287 EDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI 2346

Query: 1433 RSGQSSRGER---HGSSSGS--SSSYGQHGSGSRQSLG-HGQHGSGSGQSPSPSRGRHGS 1486
              GQ+S   R   H  SSGS  S S G       QS+  HGQ G         +RGR   
Sbjct: 2347 GHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAG 2406

Query: 1487 GSGQSSSY-----------SPYG-SGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYG 1534
             SG+S S+           S +G +G+     +G +   +  SS   H  S+ GQ + +G
Sbjct: 2407 RSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSR--HSTSQEGQDTIHG 2464

Query: 1535 QHGSSSG---------------HSSTHGQHGSTSGQSSSCGQHGAS---SGQSSSHGQHG 1576
              GSSSG               HS +H  H ++ G+S +   H  S   S Q+ +  Q G
Sbjct: 2465 HPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSG 2524

Query: 1577 SGSSQSSGYGRQGSGSGQSPGHGQRGS----GSRQSPSYGR----------HGSGSGR-- 1620
             GS  S     + S    S GH Q G     G R S ++G           H   S R  
Sbjct: 2525 DGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWS 2584

Query: 1621 -SSSSGQHGS--------------------GLGES------SGFGHHESSSGQSSSYSQH 1653
             S+S   HGS                    G G S      SG  H ++SSG  ++ S  
Sbjct: 2585 GSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHE 2644

Query: 1654 GSGSGHSSGYGQHGSRSGQSSR--GERHGSSSRSSSRYGQHG-SGSRQS----------- 1699
             + S     +G H  +S  SSR  G  HG +S +    G  G SGS+ S           
Sbjct: 2645 QARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDT 2704

Query: 1700 ---SGHGRQGSG--SGQSPSRGRHGSGLGHS--------------SSHGQHG-------- 1732
               S HG+ GS   S Q  +RGR G   GHS              SSHG  G        
Sbjct: 2705 QSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQG 2764

Query: 1733 --------------SGSGRSSSRG-PYESRSGHSSVFGQHE-SGSGHSSAYSQHGSGSGH 1776
                          S  G+ + RG P  SR G      +H    SGHS ++  H +  G 
Sbjct: 2765 SRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGR 2824

Query: 1777 F-CSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSS----SYGQQGSGSGQSPS 1831
               S+GQ GS S   +T ++E S  G   S  +H   S+ +     S   QG   G   S
Sbjct: 2825 SDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRS 2884

Query: 1832 RGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQS----------------SGFGHHE 1875
            R +  S S  S S G       WS S+ R+  GS Q                 +G GH  
Sbjct: 2885 RRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSA 2944

Query: 1876 SSSWQS-SGYTQHGSGSGHSSSYEQ--------HGS---RSGQSSR--GEQHGSSSGSSS 1921
             SS QS + +TQ  SG   +SS+EQ        HGS   +S  SSR  G  HG +S +  
Sbjct: 2945 DSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVR 3004

Query: 1922 SYGQHG-SGSRQS--------------LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY-- 1964
              G  G SGS+ S                HGQ GS        +RGR G  SG S S+  
Sbjct: 3005 DSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLY 3064

Query: 1965 -----GPYGSGSGWS--SSRGPYES-------GSGHSSGL-------GHRESRSGQSSGY 2003
                     S  GW+  S+RG   S        S HS+         GH  S  G   GY
Sbjct: 3065 QVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGY 3124

Query: 2004 GQHGS--SSGHSSTHGQHGSASGQS-SSCGQHGASSGQSSSHGQHGSGSSQSSGYGR--- 2057
                S  SSGHS +H  H ++ G+S +S GQ G+ S   ++  +  SG S      R   
Sbjct: 3125 HHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHE 3184

Query: 2058 --------------QGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGR--SSSSGQHGPGL 2101
                          QG   G      Q  S S+ S S G H   S R   S+S  H   +
Sbjct: 3185 ASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEG-HSEDSERWSGSASRNHRGSV 3243

Query: 2102 GESSGFG------HHESSSGQSSSYS---QHGSGSGHSSGYGQHGSRSGQ--SSRGERHG 2150
             E S  G      HHE  +G   S     Q G+    +S  GQ  S   Q  SS GERHG
Sbjct: 3244 QEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHG 3303

Query: 2151 S---SSGSSSRY-----GQHGSGSRQSSGHGRQGS----GSGHSP-----SRGRHGSGSG 2193
            S    S  SSR+     GQ  S  R S   G  GS      GHS      S   HG    
Sbjct: 3304 SRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGP 3363

Query: 2194 HSSSHGQH-----GSGSGRS-------SSRGPYESRSGHSSVFGQHESGSGHSSAY--SQ 2239
            H  SH +      G  SGRS       S+    ES  G +        GS H  A   S+
Sbjct: 3364 HQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSR 3423

Query: 2240 HG-SGSGHFCSQGQHGST--SGQSSTFDQEGSSTGQSSSHGQHGSGSSQS-SSYGQQGSG 2295
            H  S  G    +G  GS+    Q S ++Q    +G S SH  H +   +S +S GQ GS 
Sbjct: 3424 HSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSR 3483

Query: 2296 SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYT 2355
            S    +R    SG G   S+  H   S  + SS    SG GQS+G     +S  Q S  +
Sbjct: 3484 SASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAG---PRTSRNQGSSVS 3540

Query: 2356 QHGSGSGHSSSYEQ---------HGSRSGQSSRGERHGSSSGSS-SSYGQHGSGSRQSLG 2405
            Q     GHS   E+          GS   QS  G RH +S     + +G     SRQS  
Sbjct: 3541 QDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGT 3600

Query: 2406 H-------GQHGSGSGQSPSPSRGRHGSGSGQSSSYSPY-GSGSGWSSS-------RGPY 2450
            H       GQ  S   Q+ S +  RHGS   QS+  S + G G G +SS       RG  
Sbjct: 3601 HHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRG-- 3658

Query: 2451 ESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSS-CGQHGASSGQS 2509
             SGS  S   GH E    QS     HG +  H  +H +  ST G+S+   G+ G+   Q 
Sbjct: 3659 SSGSQASDSEGHSEDSDTQS--VSAHGQAGPHQQSHQE--STRGRSAGRSGRSGSFLYQV 3714

Query: 2510 SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH-GSGSGRSSSSGQHG 2568
            S+H Q        S +GR G  +G     G++GS   Q+    RH  S  G+ +  G  G
Sbjct: 3715 STHEQ------SESAHGRAGPSTG-----GRQGSRHEQARDSSRHSASQEGQDTIRGHPG 3763

Query: 2569 SGLGESSGFGHHES--SSGQSSSYSQHGSGSGHS-SGYGQHGSRSGQSSRGERHGSSSGS 2625
            S  G   G  H +S   SG S S+  H +  G S + +GQ GSRS          S  GS
Sbjct: 3764 SRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGS 3823

Query: 2626 SSHYGQHGSGSRQ--SSGHGRQGSGSGQSPSRG-RHGSGLGHSSSHGQHGSGSGRSSSRG 2682
                 +H   S Q  SS H + G G      R  R GS +   S    +   S R S   
Sbjct: 3824 RHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESA 3883

Query: 2683 PYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEG--SST 2740
               SR  H S   Q   GS H       GS      S  Q       SST  + G  SS 
Sbjct: 3884 ---SRNHHGSSREQSRDGSRHP------GSSHRDTASHVQSSPVQSDSSTAKEHGHFSSL 3934

Query: 2741 GQSSSY----GHRGSGSS------QSSGYGRHGAGSGQSLSHGRHGSGS---GQSS-SYG 2786
             Q S+Y      RGS  S      QS G  R    SG    HG +GS     G+S   + 
Sbjct: 3935 SQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGSADYDYGESGFRHS 3994

Query: 2787 QHGSGSGQSSG--YSQH-----GSGSGQDGYSYCKGGSNHDGGSSGSYFLSFPSSTSPYE 2839
            QHGS S  S+   + +       S  G+D   Y     N D G  G         +    
Sbjct: 3995 QHGSVSYNSNPVVFKERSDICKASAFGKDHPRYYATYINKDPGLCG----HSSDISKQLG 4050

Query: 2840 YVQEQRCYFYQ 2850
            + Q QR Y+Y+
Sbjct: 4051 FSQSQRYYYYE 4061


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score =  262 bits (670), Expect = 3e-69
 Identities = 308/1281 (24%), Positives = 424/1281 (33%), Gaps = 87/1281 (6%)

Query: 212  SGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRS------- 264
            S  S  ++ + SG+ + SG   H+   G+         G G+ S + + G +S       
Sbjct: 40   SNVSVQDELNASGTIKESGVLVHEGDRGRQENTQDGHKGEGNGSKWAEVGGKSFSTYSTL 99

Query: 265  -GQSSRGERHRSSSGSSSSYGQHGSGSRQS--LGHGRQGSGS-RQSPSHVRHGSGSGHSS 320
              +    E     +G + +YG  G   ++     +G QG  S   +       + +G++ 
Sbjct: 100  ANEEGNIEGWNGDTGKAETYGHDGIHGKEENITANGIQGQVSIIDNAGATNRSNTNGNTD 159

Query: 321  SHGQHGSGSSYSYSR--------GHYESGS-GQTSGFGQHESGSGQSSGYSKHGSGSGHS 371
             + Q+G      ++         G   +GS   T    +    S ++ G +   +   +S
Sbjct: 160  KNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINS 219

Query: 372  SSQGQHGS--TSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQR 429
               G   +  T G    +G   S    S + G  E     S       +G+G+   +  +
Sbjct: 220  KRNGTKEAEVTPGTGEDAGLDNSDGSPSGN-GADEDEDEGSGDDEDEEAGNGKDSSNNSK 278

Query: 430  GSGSGQSPSSGQHGTGFGRSSSSGPYVSGSG----YSSGFGHHESSSEHSSGYTQHGSGS 485
            G           H +  G++S S  Y    G    ++   G   S SE +S      +GS
Sbjct: 279  GQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGS 338

Query: 486  --------------------------GHSSGHGQ------HGSRSGQSSRGERQGSSAGS 513
                                       H+ G  Q       G  SG  +  +  G     
Sbjct: 339  QRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEG 398

Query: 514  SSSYGQH----GSGSRQSLGHSRHGSGSGQSPSP-SRGRHESGSRQSSSYGPHGYGSGRS 568
                GQH    G G+ ++ G   +  G GQ   P ++  H +    S+S G   Y     
Sbjct: 399  KEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDK 458

Query: 569  SSRGPYESGSGHSSGLGHQESRS-GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHG 627
            S +G   + S  S+G     S S   SS  G    +S  S  +G    + G         
Sbjct: 459  SMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDST 518

Query: 628  ATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHS--SSYGQHGSGSGWS 685
            + +  S S+G   +G+  + +     SG G+S S     SD  +S  SS       S  +
Sbjct: 519  SDTNNSDSNGNGNNGNDDNDK---SDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSN 575

Query: 686  SSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSS 745
            SS+    S S  S      S    +S  S   S SS SS           SS+SE   S 
Sbjct: 576  SSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSD 635

Query: 746  SGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCG 805
            S   S      S     +      S S +S        SS  SSS     S  S  SS  
Sbjct: 636  SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS 695

Query: 806  HYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSS 865
               S S  +S     +S S    S + ++S   SS     S S  SS S     SS  S 
Sbjct: 696  SNSSESSDSSDSSDSDS-SDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSD 754

Query: 866  SYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSG 925
            S    +S++   S      S S  S         S  S S     S    +SS     S 
Sbjct: 755  SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSD 814

Query: 926  SGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQ 985
            S  S       SS  S       S     SS    GS S  S+RS+   SS  S SS   
Sbjct: 815  SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSS 874

Query: 986  HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSG 1045
            + S S  S       S S +S + S     S S  S S     S     SS     S S 
Sbjct: 875  NSSDSSDS-------SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESS 927

Query: 1046 HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQH 1105
            +SS   +    S  S       SS+   S++    S S  SS      +S   +SS    
Sbjct: 928  NSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSD 987

Query: 1106 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESS 1165
             S SS SS      S S  S         S  S S     S +   SS     S   +SS
Sbjct: 988  SSDSSDSSD-SSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSS 1046

Query: 1166 GFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSG 1225
                 +SS    SS S   S S  SS        S  S   E   SS  S+S      S 
Sbjct: 1047 -----DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101

Query: 1226 SRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFG 1285
            S  SS        S  S S     S     SS     S S  SS        S  S    
Sbjct: 1102 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161

Query: 1286 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQ 1345
              +S     S+ S   S S           +S  S + D   SS    SS     S SS 
Sbjct: 1162 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1221

Query: 1346 SSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHE 1405
            SS        +  S S     S    +SS     S S  S+S     S S   SG G++ 
Sbjct: 1222 SSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNN 1281

Query: 1406 SSSWQSSGCTQHGSGSGHSSS 1426
             S    S     GS S HS+S
Sbjct: 1282 GS---DSDSDSEGSDSNHSTS 1299



 Score =  262 bits (670), Expect = 3e-69
 Identities = 301/1280 (23%), Positives = 429/1280 (33%), Gaps = 73/1280 (5%)

Query: 1157 HGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS--------GQSSRGER 1208
            + SG  + SG   HE   G+  +      G G+ S + + G +S         +    E 
Sbjct: 49   NASGTIKESGVLVHEGDRGRQENTQDGHKGEGNGSKWAEVGGKSFSTYSTLANEEGNIEG 108

Query: 1209 HGSSSGSSSHYGQHGSGSRQSS--GHGRQGSGS----GHSPSRGRHGSGLGHSSSHGQHG 1262
                +G +  YG  G   ++ +   +G QG  S      + +R         ++ +G  G
Sbjct: 109  WNGDTGKAETYGHDGIHGKEENITANGIQGQVSIIDNAGATNRSNTNGNTDKNTQNGDVG 168

Query: 1263 SGSGRSS-----SRGPYESRSGHSS-----VFGQHESGSGHSSAYSQHGSGSGHFCSQGQ 1312
                          GP  + S +S+     +        G++S  +   +   +   + +
Sbjct: 169  DAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAE 228

Query: 1313 HGSTSGQSSTFDQ-EGSSTGQSSSYGH-RGSGSSQS--SGYGRHGAGSGQSPSRGRHGSG 1368
                +G+ +  D  +GS +G  +      GSG  +   +G G+  + + +      HG  
Sbjct: 229  VTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKE 288

Query: 1369 SGHSSSYGQHGSGSGWSSSSGR---HGSGSGQSSGFGHHESSSWQSSGCTQHGSGS---G 1422
              H SS GQ+     +    G+   H    G  +      S+       +Q    +    
Sbjct: 289  DDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLN 348

Query: 1423 HSSSY----------EQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 1472
            H  S           E H     Q    E  G SSG+ +   + G G+      GQHG  
Sbjct: 349  HRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMI 408

Query: 1473 SGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSG 1532
             G+    ++G   +  G      P G+  G S++        S S+  G+        S 
Sbjct: 409  LGKGNVKTQGEVVNIEGPGQKSEP-GNKVGHSNT-------GSDSNSDGYDSYDFDDKSM 460

Query: 1533 YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS 1592
             G   +SS  S+ +    S S  +SS    G +S  S     +G+GS            +
Sbjct: 461  QGDDPNSSDESNGNDDANSESDNNSS--SRGDASYNSDESKDNGNGSDSKGAEDDDSDST 518

Query: 1593 GQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ 1652
              +      G+G+  +    +  SG G+S SS    S   +SS      +SS  S S   
Sbjct: 519  SDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSS---DSS------NSSDSSDSSDS 569

Query: 1653 HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQS 1712
              S S  SS      S S  SS  +   SS+ S S      S S  SS      S S +S
Sbjct: 570  DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS 629

Query: 1713 PSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGS 1772
             S          SS      S     SS     S S  SS     +S    SS+ S + S
Sbjct: 630  ESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSS--DSSDSSDSSSSSDSSNSS 687

Query: 1773 GSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSR 1832
             S           +S  S + D + S +  SS+     S SS SS      + S  S S 
Sbjct: 688  DSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS 747

Query: 1833 GRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSG 1892
                S     SS   + S S  S SS    S    +S   +  S+S  SS  +     S 
Sbjct: 748  DSSNSSDSSDSSDSSNSSDS--SDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805

Query: 1893 HSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG 1952
             S S +   S    SS      +SS SS S     S        G     S +S S +  
Sbjct: 806  SSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSS 865

Query: 1953 RHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGH 2012
                 S  S+S     S     SS     S S +SS     +S +   S    + S S  
Sbjct: 866  DSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSE 925

Query: 2013 SSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 2072
            SS    + ++S  S+S     +S   +SS   + S SS SS      S S  S       
Sbjct: 926  SSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS----DSSDSNSSDSSDSSN 981

Query: 2073 SGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 2132
            S      S     S S  SS+S         S      +SS+   SS S   S S  SS 
Sbjct: 982  SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041

Query: 2133 YGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGS 2192
                   S  S       SS  S S      S S  SS        S  S S     S  
Sbjct: 1042 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101

Query: 2193 GHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ 2252
               SS     S S  SS        S  S      +S +   S+ S   S S        
Sbjct: 1102 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161

Query: 2253 HGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHS 2312
               +S  S + D   SS    SS     S SS SS        S  S S     S     
Sbjct: 1162 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1221

Query: 2313 SSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGS 2372
            SS     S S  SS S      S  S+     +SS   SS  T   +    S S   +G+
Sbjct: 1222 SSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSS--DSSDSTSDSNDESDSQSKSGNGN 1279

Query: 2373 RSGQSSRGERHGSSSGSSSS 2392
             +G  S  +  GS S  S+S
Sbjct: 1280 NNGSDSDSDSEGSDSNHSTS 1299



 Score =  260 bits (664), Expect = 2e-68
 Identities = 326/1331 (24%), Positives = 455/1331 (34%), Gaps = 112/1331 (8%)

Query: 1198 SRSGQSSRGERHGSS----SGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLG 1253
            +RS  S + E + S     SG   H G  G       GH  +G+GS  +   G+  S   
Sbjct: 38   ARSNVSVQDELNASGTIKESGVLVHEGDRGRQENTQDGHKGEGNGSKWAEVGGKSFST-- 95

Query: 1254 HSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQH 1313
            +S+   + G+  G +   G  E+  GH  + G+ E+ + +                    
Sbjct: 96   YSTLANEEGNIEGWNGDTGKAETY-GHDGIHGKEENITANG------------------- 135

Query: 1314 GSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSS-GYGRHGAGSGQSPSRGRHGSGSGHS 1372
                GQ S  D  G+ T +S++ G+    +     G   H          G   +GS +S
Sbjct: 136  --IQGQVSIIDNAGA-TNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNS 192

Query: 1373 S---------SYGQHGSGSGWSS--SSGRHGS-------GSGQSSGFGHHESSSWQSSGC 1414
            +         S    G+ S  +   +S R+G+       G+G+ +G  + + S   +   
Sbjct: 193  TDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGAD 252

Query: 1415 TQHGSGSGHSSSYEQ-HGSRSGQSSRGER---HGSSSGSSSSYGQHGSGSRQSLGHGQHG 1470
                 GSG     E  +G  S  +S+G+    HG      SS GQ+              
Sbjct: 253  EDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEY-------- 304

Query: 1471 SGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSH---SSGLGHRESRS 1527
                  P      H    G  +S S   S         P ++GS     +  L HRES+ 
Sbjct: 305  ----YDPEGKEDPHNEVDGDKTSKSEENSAGI------PEDNGSQRIEDTQKLNHRESKR 354

Query: 1528 GQSSGYGQHGSSS-GHSSTHGQH--GSTSGQSSSCGQHGASSGQSSSHGQHG----SGSS 1580
             ++    +  + + G S   G    G +SG  +   + G  +      GQHG     G+ 
Sbjct: 355  VENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNV 414

Query: 1581 QSSGYGRQGSGSGQSP------GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGES 1634
            ++ G      G GQ        GH   GS S    S G         S  G   +   ES
Sbjct: 415  KTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSN---SDGYDSYDFDDKSMQGDDPNSSDES 471

Query: 1635 SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGS 1694
            +  G+ +++S   ++ S  G  S +S     +G+ S      +    S+  ++    +G+
Sbjct: 472  N--GNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGN 529

Query: 1695 GSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF 1754
            G+  +  + +  SG G+S S     S    +SS     S S  S S    +S S  S   
Sbjct: 530  GNNGNDDNDKSDSGKGKSDSSDSDSSD-SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSS 588

Query: 1755 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSS 1814
               +S S  SS  S     S    S     S+  +S +   E  S+   S      S SS
Sbjct: 589  DSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS 648

Query: 1815 QSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 1874
             SS        S  S S       S  S S     S S   SS+    S S  SS     
Sbjct: 649  DSSDNSDSSDSSNSSNS-------SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSES 701

Query: 1875 ESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSL 1934
              SS  S   +   S S +S+S +   S S  SS       SS SS S     S      
Sbjct: 702  SDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 761

Query: 1935 GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRE 1994
             +    S S  S   S   + S S  SS+       S  S S    +S     S      
Sbjct: 762  SNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS 821

Query: 1995 SRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG 2054
            + S  S+      SS+   S+     S    S S  +  +S+   SS     S SS SS 
Sbjct: 822  NSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS- 880

Query: 2055 YGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSS 2114
                 S S +S         S  S S     S S  SS S         S+   +  SS 
Sbjct: 881  ---DSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD 937

Query: 2115 GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGR 2174
              +SS S   S S +SS    + S S  SS      SS  S S      S S  SS    
Sbjct: 938  SSNSSDSSDSSDSSNSSD-SSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSD 996

Query: 2175 QGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHS 2234
                S  S S     S    +SS   + S S  SS        S  S      +S    +
Sbjct: 997  SSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSN 1056

Query: 2235 SAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGS 2294
            S+ S   S S           +S  S + D   SS    SS     S SS SS       
Sbjct: 1057 SSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1116

Query: 2295 GSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGY 2354
             S  S S     S     SS   + S S  SS S      S  S      +SS    S  
Sbjct: 1117 SSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSD 1176

Query: 2355 TQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSG 2414
            + + S S  SS        S  S   +   SS  S SS     S S  S       S S 
Sbjct: 1177 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS----SDSSDSN 1232

Query: 2415 QSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYG 2474
            +S   S     S S  SS  S   S S  S+S    ES S   SG G   + +G  S   
Sbjct: 1233 ESSDSSDSSDSSDSSNSSDSSD-SSDSSDSTSDSNDESDSQSKSGNG---NNNGSDSDSD 1288

Query: 2475 QHGSSSGHSST 2485
              GS S HS++
Sbjct: 1289 SEGSDSNHSTS 1299



 Score =  258 bits (660), Expect = 5e-68
 Identities = 318/1342 (23%), Positives = 440/1342 (32%), Gaps = 140/1342 (10%)

Query: 549  ESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSS 608
            + G ++++  G  G G+G   +    +S S +S+    + +  G +   G+   + GH  
Sbjct: 65   DRGRQENTQDGHKGEGNGSKWAEVGGKSFSTYSTLANEEGNIEGWNGDTGK-AETYGHDG 123

Query: 609  THGQHGSTS-----GQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRG 663
             HG+  + +     GQ S     GAT+ +S+++G     ++Q+   G  G          
Sbjct: 124  IHGKEENITANGIQGQVSIIDNAGATN-RSNTNGNTDK-NTQNGDVGDAG---------- 171

Query: 664  RHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGS----- 718
             H  D       G   +GS  S+ N     +       G+ S         ++G+     
Sbjct: 172  -HNEDVAVVQEDGPQVAGSNNSTDNEDE-IIENSCRNEGNTSEITPQINSKRNGTKEAEV 229

Query: 719  --GSSHSSGY-RKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHS 775
              G+   +G     GS SG  +  ++   S          G    + +G+G+  S +   
Sbjct: 230  TPGTGEDAGLDNSDGSPSGNGADEDEDEGS----------GDDEDEEAGNGKDSSNNSKG 279

Query: 776  PSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSAS 835
                 HG    H SS GQ+                           S S + Y   G   
Sbjct: 280  QEGQDHGKEDDHDSSIGQN---------------------------SDSKEYYDPEGKED 312

Query: 836  GHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGR---------HGSG 886
             H    G   S S ++S+    D+ S +       +  +H  S R           H  G
Sbjct: 313  PHNEVDGDKTSKSEENSAGIPEDNGSQRIEDT---QKLNHRESKRVENRITKESETHAVG 369

Query: 887  SGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSS-----------GFGHK 935
              Q  G   +G  SG        G G+      G+HG   G+ +           G G K
Sbjct: 370  KSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQK 429

Query: 936  SSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLG 995
            S  G   G++  GS S +S  Y+ +                    S  G   + S +S G
Sbjct: 430  SEPGNKVGHSNTGSDS-NSDGYDSY---------------DFDDKSMQGDDPNSSDESNG 473

Query: 996  HGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRES 1055
            +    S S  + S SRG     S +S       +G+G S S+G  +  S  +S     ++
Sbjct: 474  NDDANSESDNNSS-SRGDASYNSDESKD-----NGNG-SDSKGAEDDDSDSTS-----DT 521

Query: 1056 RSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGY 1115
             +  S+G G +G+     S  G+  S S  S S     +S    SS       +S S   
Sbjct: 522  NNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSD 581

Query: 1116 GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 1175
                  S  S       S S  S         S  S SS          S     +S S 
Sbjct: 582  SSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSD 641

Query: 1176 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQ 1235
             S S S   S +  SS      + S  S   +   SSS S S      S S  SS     
Sbjct: 642  SSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSES 701

Query: 1236 GSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 1295
               S  S S     S   +S+S     S S  SS        S +SS     +S     S
Sbjct: 702  SDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD-------SSNSS-----DSSDSSDS 749

Query: 1296 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAG 1355
            + S   S S    +      +S  S + D   SS    SS     S SS SS        
Sbjct: 750  SNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS 809

Query: 1356 SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCT 1415
            S  S S     S S  SS+       S  S SS    S  G  S   +   SS  S    
Sbjct: 810  SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD 869

Query: 1416 QHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ 1475
               S +   SS     + S  SS      +SS S SS   + S S  S       S S  
Sbjct: 870  SSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDS-------SNSSD 922

Query: 1476 SPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQ 1535
            S   S     S S  SS+ S     S  S+S     S SS+SS   +    S  +S    
Sbjct: 923  SSESSNSSDNSNSSDSSNSSDSSDSSDSSNS-----SDSSNSSDSSNSSDSSDSNSSDSS 977

Query: 1536 HGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQS 1595
              S+S  SS       +S  S S     +S    SS   + S SS SS        S  S
Sbjct: 978  DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037

Query: 1596 PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGS 1655
                   S      S   + S S  SS S         S      ESS    SS S   S
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097

Query: 1656 GSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSR 1715
             S  SS        S  S   +   SS  S S      S S  SS        S  S S 
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSS 1157

Query: 1716 GRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSG 1775
                S     SS     S S  SS        S  S      +S     S+ S   S S 
Sbjct: 1158 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1217

Query: 1776 HFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRH 1835
                      +S  + + D   SS    SS+    S SS SS      +    S S+  +
Sbjct: 1218 DSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGN 1277

Query: 1836 GSGSGHSSSYGQHGSGSGWSSS 1857
            G+ +G  S     GS S  S+S
Sbjct: 1278 GNNNGSDSDSDSEGSDSNHSTS 1299



 Score =  256 bits (655), Expect = 2e-67
 Identities = 312/1309 (23%), Positives = 441/1309 (33%), Gaps = 100/1309 (7%)

Query: 1564 ASSGQSSSHGQHGSGSSQSSGY----GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG 1619
            A S  S     + SG+ + SG     G +G       GH   G+GS+ +   G+  S S 
Sbjct: 38   ARSNVSVQDELNASGTIKESGVLVHEGDRGRQENTQDGHKGEGNGSKWAEVGGK--SFST 95

Query: 1620 RSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERH 1679
             S+ + + G+  G +         +G++ +Y   G   G       +G + GQ S  +  
Sbjct: 96   YSTLANEEGNIEGWNG-------DTGKAETYGHDGI-HGKEENITANGIQ-GQVSIIDNA 146

Query: 1680 GSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSS 1739
            G+++RS++            +G+  + + +G     G H   +      G   +GS  S+
Sbjct: 147  GATNRSNT------------NGNTDKNTQNGDVGDAG-HNEDVAVVQEDGPQVAGSNNST 193

Query: 1740 SRGPYESRS-----GHSSVFGQHESGSGHSSAYSQHGSGSGHFCS-QGQHGSTSGQSSTF 1793
                    +     G++S      +   + +  ++   G+G         GS SG  +  
Sbjct: 194  DNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADE 253

Query: 1794 DQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSG 1853
            D++  S         +G  SS +S  GQ+G           HG    H SS GQ+     
Sbjct: 254  DEDEGSGDDEDEEAGNGKDSSNNSK-GQEGQD---------HGKEDDHDSSIGQNSDSKE 303

Query: 1854 W-----------------SSSSGRHGSGSGQSSG---------FGHHESSSWQSSGYTQ- 1886
            +                 +S S  + +G  + +G           H ES   ++    + 
Sbjct: 304  YYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKES 363

Query: 1887 --HGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHG----SGSRQSLGHGQHG 1940
              H  G       E  G  SG  +  ++ G  +      GQHG     G+ ++ G   + 
Sbjct: 364  ETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNI 423

Query: 1941 SGSGQSPSPSRGRHGSGSGQSSSYGPYGSGS-GWSSSRGPYESGSGHSSGLGHRESRSGQ 1999
             G GQ   P      S +G  S+   Y S      S +G   + S  S+G     S S  
Sbjct: 424  EGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDN 483

Query: 2000 SSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 2059
            +S     G +S +S     +G+ S    +      S+  +++   +G+G++ +    +  
Sbjct: 484  NSS--SRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSD 541

Query: 2060 SGSGQSPGHGQRGS-GSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSS 2118
            SG G+S       S  S  S S     S S  S+SS        +SS     +SS   +S
Sbjct: 542  SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNS 601

Query: 2119 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSG 2178
            S S   S S  SS           SS+ E   S S S S      S     +      S 
Sbjct: 602  SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN 661

Query: 2179 SGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYS 2238
            S +S         S  SSS     S     SS     S S  SS     +S     S+ S
Sbjct: 662  SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721

Query: 2239 QHGSGSGHFCSQGQHGSTSGQSS-TFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSG 2297
                      S     S S  SS + D   SS    SS   + S SS SS        S 
Sbjct: 722  NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781

Query: 2298 QSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQH 2357
             S S     S     SS     S S  SS S    S S  S      +SS+   S  + +
Sbjct: 782  SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDS----SDSSDSDSSNSSDSSNSSDSSDSSN 837

Query: 2358 GSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSP 2417
             S S  SS     GS S  S+R +   SS  S SS   + S S  S       S S +S 
Sbjct: 838  SSDSSDSSD-SSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS-------SDSNESS 889

Query: 2418 SPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHG 2477
            + S     S S  S S     S     SS     S S +SS   +    S  S       
Sbjct: 890  NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSD 949

Query: 2478 SSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG 2537
            SS+   S++    S S  SS      +S   +SS     S SS SS      + S  S  
Sbjct: 950  SSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1009

Query: 2538 HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS 2597
                 S +    S     S S  SS S         S      +SS+   SS S   S S
Sbjct: 1010 SDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1069

Query: 2598 GHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGR 2657
              SS        S  S   +   SS  S S      S S  SS        S  S S   
Sbjct: 1070 SDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1129

Query: 2658 HGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHF 2717
              S     SS+    S S  SS           S      +S     S+ S   S S   
Sbjct: 1130 SDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1189

Query: 2718 CSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGS 2777
                    +S  S + D   SS    SS     S SS SS        S  S S     S
Sbjct: 1190 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNS 1249

Query: 2778 GSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGS 2826
                 SS     +        SQ  SG+G +       GS+ D  S GS
Sbjct: 1250 SDSSDSSDSSDSTSDSNDESDSQSKSGNGNN------NGSDSDSDSEGS 1292



 Score =  256 bits (653), Expect = 3e-67
 Identities = 298/1305 (22%), Positives = 427/1305 (32%), Gaps = 84/1305 (6%)

Query: 1337 GHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 1396
            G RG   +   G+   G GS  +   G+  S S +S+   + G+  GW+  +G+      
Sbjct: 64   GDRGRQENTQDGHKGEGNGSKWAEVGGK--SFSTYSTLANEEGNIEGWNGDTGK------ 115

Query: 1397 QSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQH 1456
             +  +GH +    +    T +G   G  S  +  G+ +  ++ G    ++         H
Sbjct: 116  -AETYGH-DGIHGKEENITANGI-QGQVSIIDNAGATNRSNTNGNTDKNTQNGDVGDAGH 172

Query: 1457 GSGSRQSLGHGQHGSGSGQSPSPSRG---RHGSGSGQSSSYSPYGSGSGWSSSRGPYESG 1513
                      G   +GS  S               G +S  +P  +     +       G
Sbjct: 173  NEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPG 232

Query: 1514 SSHSSGLGHRE-SRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH 1572
            +   +GL + + S SG  +   +   S         +G  S  +S  GQ G   G+   H
Sbjct: 233  TGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSK-GQEGQDHGKEDDH 291

Query: 1573 GQH-GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGL 1631
                G  S     Y  +G     +   G + S S ++ +     +GS R          +
Sbjct: 292  DSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQR----------I 341

Query: 1632 GESSGFGHHESSSGQSSSYSQ---HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSR 1688
             ++    H ES   ++    +   H  G     G    G  SG  +  +  G  +     
Sbjct: 342  EDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKED 401

Query: 1689 YGQHG----SGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPY 1744
             GQHG     G+ ++ G      G GQ   +   G+ +GHS++              G  
Sbjct: 402  KGQHGMILGKGNVKTQGEVVNIEGPGQ---KSEPGNKVGHSNT--------------GSD 444

Query: 1745 ESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS 1804
             +  G+ S     +S  G     S   +G+    S+  + S+S   ++++ + S      
Sbjct: 445  SNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESK----- 499

Query: 1805 SHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 1864
                +G+GS    +       +  + +   +G+G+  +    +  SG G S SS    S 
Sbjct: 500  ---DNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSD 556

Query: 1865 SGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYG 1924
            S  SS       S    S  +     S   SS       S  S+  +   SS  S SS  
Sbjct: 557  SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS 616

Query: 1925 QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGS 1984
               S S+      +  S    S S S   + S S  +S      S    +SS     S S
Sbjct: 617  SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSD-----SSDSSNSSNSSDSSDS 671

Query: 1985 GHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQ 2044
              SS     +S S   S      S S  SS   +   +S  S S     + S  S+S   
Sbjct: 672  SDSS-----DSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726

Query: 2045 HGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGES 2104
              S SS SS        S  S       S      S     S S  SS S         +
Sbjct: 727  DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD-----SSN 781

Query: 2105 SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGS 2164
            S   +  S+S  SS  S     S  S       S    SS      +SS SS       S
Sbjct: 782  SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841

Query: 2165 GSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRS--SSRGPYESRSGHSS 2222
                 S  G     S  S S     S     SS+    S S  S  SS     S S +SS
Sbjct: 842  SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS 901

Query: 2223 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSG 2282
                 +S +   S+ S + S S    +   + ++S  S++ D   SS   +SS   + S 
Sbjct: 902  DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961

Query: 2283 SSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFG 2342
            SS SS      S      S     S S  SS        S  S SS    S    +S   
Sbjct: 962  SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021

Query: 2343 HHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQ 2402
             + S S  SS  +     S  S S     S S  SS       SS SS S     S    
Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDS-----SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1076

Query: 2403 SLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGH 2462
                    S S  S + S     S S  SS  S     S  S S    +S     S    
Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136

Query: 2463 RESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQS 2522
              S S  SS   +  SS    S+     S S  SS       SS  S S     S  S  
Sbjct: 1137 DSSNSSDSSDSSE--SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1194

Query: 2523 SGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHES 2582
            S      S S  S         S  S S     S     SS     S   +SS       
Sbjct: 1195 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSD 1254

Query: 2583 SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSS 2627
            SS  S S S     S   S  G +G+ +G  S  +  GS S  S+
Sbjct: 1255 SSDSSDSTSDSNDESDSQSKSG-NGNNNGSDSDSDSEGSDSNHST 1298



 Score =  255 bits (652), Expect = 4e-67
 Identities = 321/1352 (23%), Positives = 443/1352 (32%), Gaps = 111/1352 (8%)

Query: 986  HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSG 1045
            + SG+ +  G   H    G+  +   G  G G+G           S W+   G  +S S 
Sbjct: 49   NASGTIKESGVLVHEGDRGRQENTQDGHKGEGNG-----------SKWAEVGG--KSFST 95

Query: 1046 HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQH 1105
            +S+      +  G +   G+   + GH   HG+  + +      G  G  S   ++   +
Sbjct: 96   YSTLANEEGNIEGWNGDTGK-AETYGHDGIHGKEENITAN----GIQGQVSIIDNAGATN 150

Query: 1106 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH-----GSG 1160
             S ++ ++    Q    G + GH +  +  ++    G   +GS  S+ +           
Sbjct: 151  RSNTNGNTDKNTQNGDVGDA-GHNEDVAVVQED---GPQVAGSNNSTDNEDEIIENSCRN 206

Query: 1161 LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYG 1220
             G +S      +S    +  ++   G+G  +G     S    S  G       GS     
Sbjct: 207  EGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDN--SDGSPSGNGADEDEDEGS----- 259

Query: 1221 QHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGH 1280
              G    + +G+G+  S +        HG    H SS GQ+   S       P      H
Sbjct: 260  --GDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQN---SDSKEYYDPEGKEDPH 314

Query: 1281 SSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRG 1340
            + V G   S S  +SA     +GS       +         +   E   T +S ++    
Sbjct: 315  NEVDGDKTSKSEENSAGIPEDNGSQRI----EDTQKLNHRESKRVENRITKESETHA--- 367

Query: 1341 SGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGS--GSGWSSSSGR--HGSGSG 1396
             G SQ  G    G  SG        G G+      GQHG   G G   + G   +  G G
Sbjct: 368  VGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPG 427

Query: 1397 QSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSS-GSSSSYGQ 1455
            Q S                + G+  GHS++        G  S  + + S      S  G 
Sbjct: 428  QKS----------------EPGNKVGHSNT--------GSDSNSDGYDSYDFDDKSMQGD 463

Query: 1456 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSS 1515
              + S +S G+    S S  + S SRG     S +S       +G+G S S+G  +  S 
Sbjct: 464  DPNSSDESNGNDDANSESDNNSS-SRGDASYNSDESKD-----NGNG-SDSKGAEDDDSD 516

Query: 1516 HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQH 1575
             +S     ++ +  S+G G +G+     S  G+  S S  S S     +S    SS    
Sbjct: 517  STS-----DTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDS 571

Query: 1576 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESS 1635
               +S S         S  S       S S  S         S  S SS          S
Sbjct: 572  SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631

Query: 1636 GFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSG 1695
                 +S S  S S S   S +  SS      + S  S   +   SSS S S      S 
Sbjct: 632  DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691

Query: 1696 SRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFG 1755
            S  SS        S  S S     S   +S+S     S S  SS        S +SS   
Sbjct: 692  SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD-------SSNSS--- 741

Query: 1756 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQ 1815
              +S     S+ S   S S    +      +S  S + D   SS    SS+    S SS 
Sbjct: 742  --DSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSN 799

Query: 1816 SSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHE 1875
            SS        S  S S     S S  SS+       S  S SS    S  G  S   +  
Sbjct: 800  SSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRS 859

Query: 1876 SSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLG 1935
             SS  S       S +   SS     + S  SS      +SS S SS   + S S  S  
Sbjct: 860  DSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDS-- 917

Query: 1936 HGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRES 1995
                 S S  S   S     S S  SS+     S     SS     S S +SS   +   
Sbjct: 918  -----SNSSDSSESSNSSDNSNSSDSSN-----SSDSSDSSDSSNSSDSSNSSDSSNSSD 967

Query: 1996 RSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGY 2055
             S  +S      S+S  SS       +S  S S     +S    SS   + S SS SS  
Sbjct: 968  SSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDS 1027

Query: 2056 GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSG 2115
                  S  S       S      S   + S S  SS S         S      ESS  
Sbjct: 1028 SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS 1087

Query: 2116 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQ 2175
              SS S   S S  SS        S  S   +   SS  S S      S S  SS     
Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDS 1147

Query: 2176 GSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 2235
               S  S S     S     SS     S S  SS        S  S      +S     S
Sbjct: 1148 SESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1207

Query: 2236 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 2295
            + S   S S           +S  + + D   SS    SS+    S SS SS      + 
Sbjct: 1208 SDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSND 1267

Query: 2296 SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSS 2327
               S S+  +G+ +G  S     GS S  S+S
Sbjct: 1268 ESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299



 Score =  254 bits (648), Expect = 1e-66
 Identities = 293/1144 (25%), Positives = 394/1144 (34%), Gaps = 79/1144 (6%)

Query: 152  TESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSG 211
            T  I+ +++ +R+ + +     G     G  NSD   S          G   +  +  +G
Sbjct: 210  TSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEE-AG 268

Query: 212  SGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSG----YSQHGSGSGHSSGYGQHGSRSGQS 267
            +G+ SSN++ G           H SS GQ+S     Y   G    H+   G   S+S ++
Sbjct: 269  NGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEEN 328

Query: 268  SRG-------------------ERHRSSSGSSSSYGQHGSGSRQSLGHGRQG--SGSRQS 306
            S G                   E  R  +  +     H  G  Q  G   +G  SG+R  
Sbjct: 329  SAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNI 388

Query: 307  PSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGS 366
               V  G G+      GQHG              G+ +T G   +  G GQ S   + G+
Sbjct: 389  TKEV--GKGNEGKEDKGQHGMILG---------KGNVKTQGEVVNIEGPGQKS---EPGN 434

Query: 367  GSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGH 426
              GHS+       T   ++S G         S  G   ++S  S+G    +S S  +   
Sbjct: 435  KVGHSN-------TGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSS- 486

Query: 427  GQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSG 486
              RG  S  S  S  +G G   S S G     S  +S     ++++  S+G   +G+   
Sbjct: 487  -SRGDASYNSDESKDNGNG---SDSKGAEDDDSDSTS-----DTNNSDSNGNGNNGNDDN 537

Query: 487  HSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRG 546
              S  G+  S S  S   +   SS  S SS       +  S   S     S  S S S  
Sbjct: 538  DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSD 597

Query: 547  RHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGH 606
               S S  SS        S  S S       S   S     +S+S  S       S +  
Sbjct: 598  --SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSD 655

Query: 607  SSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHG 666
            SS      ++S  S S     ++S   SS+    S SS SS   +    S  S S     
Sbjct: 656  SSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDS 715

Query: 667  SDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGY 726
            SD  +S+S     S S   SS+  + S S  SS   + S S  SS  S + S SS SS  
Sbjct: 716  SDSSNSNSSDSDSSNSS-DSSDSSNSSDSSDSSDSSNSSDSSDSSD-SSNSSDSSDSSD- 772

Query: 727  RKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSG 786
                S S  SS S    +SS  S S     S +   S      S S  S S     SS  
Sbjct: 773  SSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDS 832

Query: 787  HSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGS 846
              SS+    S +S SS     +S +   S      S S    +   S+    S++  + S
Sbjct: 833  SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS 892

Query: 847  TSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSY 906
             S  SS+S   DSS   +SS     S S  +S      S S  +       + S  S S 
Sbjct: 893  DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS----ESSNSSDNSNSSDSSNSSDSSDSS 948

Query: 907  GRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQ 966
                S    +SS   + S S  S+      SS  S       S     SS   + S S  
Sbjct: 949  DSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSD 1008

Query: 967  SSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGP 1026
            SS S    +SS SS+S     S            S S  S   S   + S S  SS    
Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1068

Query: 1027 YRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 1086
                S  S S    ES     S      S S  SS      S S  SS       +S  S
Sbjct: 1069 SSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSS----DSSDSSDSSDSSDSSDSSNSS 1124

Query: 1087 SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS 1146
             S     +S    SS+    S SS+SS      S S  S         S  S S     S
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSESS----DSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1180

Query: 1147 GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 1206
                 SS     S   +SS     +SS    SS S   S S  SS        S  +   
Sbjct: 1181 SDSSDSSDSSDSSDSSDSS-----DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESS 1235

Query: 1207 ERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSG 1266
            +   SS  S S      S S  SS      +    S S+  +G+  G  S     GS S 
Sbjct: 1236 DSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSN 1295

Query: 1267 RSSS 1270
             S+S
Sbjct: 1296 HSTS 1299



 Score =  251 bits (641), Expect = 7e-66
 Identities = 316/1326 (23%), Positives = 436/1326 (32%), Gaps = 102/1326 (7%)

Query: 1482 GRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSG 1541
            G  G        +   G+GS W+   G  +S S++S+      +  G +   G+   + G
Sbjct: 64   GDRGRQENTQDGHKGEGNGSKWAEVGG--KSFSTYSTLANEEGNIEGWNGDTGK-AETYG 120

Query: 1542 HSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQR 1601
            H   HG+  + +      G  G  S   ++   + S ++ ++    Q    G + GH + 
Sbjct: 121  HDGIHGKEENITAN----GIQGQVSIIDNAGATNRSNTNGNTDKNTQNGDVGDA-GHNED 175

Query: 1602 GSGSRQSPSYGRHGSGSGRSSSSGQH-----GSGLGESSGFGHHESSSGQSSSYSQHGSG 1656
             +  ++    G   +GS  S+ +            G +S      +S    +  ++   G
Sbjct: 176  VAVVQED---GPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPG 232

Query: 1657 SGHSSGY-GQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSR 1715
            +G  +G     GS SG  +  +    S          G    + +G+G+  S + +    
Sbjct: 233  TGEDAGLDNSDGSPSGNGADEDEDEGS----------GDDEDEEAGNGKDSSNNSKGQEG 282

Query: 1716 GRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSG 1775
              HG    H SS GQ+   S       P      H+ V G   S S  +SA     +GS 
Sbjct: 283  QDHGKEDDHDSSIGQN---SDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQ 339

Query: 1776 HFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRH 1835
                  +         +   E   T +S +H     G SQ      +G  SG        
Sbjct: 340  RI----EDTQKLNHRESKRVENRITKESETHAV---GKSQDKGIEIKGPSSGNRNITKEV 392

Query: 1836 GSGSGHSSSYGQHGS--GSGWSSSSGR--HGSGSGQSSGFGHHESSSWQSSGYTQHGSGS 1891
            G G+      GQHG   G G   + G   +  G GQ S                + G+  
Sbjct: 393  GKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKS----------------EPGNKV 436

Query: 1892 GHSSSYEQHGSRSGQSSRGEQHGSSS-GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPS 1950
            GHS++        G  S  + + S      S  G   + S +S G+    S S  + S S
Sbjct: 437  GHSNT--------GSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSS-S 487

Query: 1951 RGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSS 2010
            RG     S +S       +G+G S S+G  +  S  +S     ++ +  S+G G +G+  
Sbjct: 488  RGDASYNSDESKD-----NGNG-SDSKGAEDDDSDSTS-----DTNNSDSNGNGNNGNDD 536

Query: 2011 GHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 2070
               S  G+  S S  S S     +S    SS       +S S         S  S     
Sbjct: 537  NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSS 596

Query: 2071 RGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 2130
              S S  S         S  S SS          S     +S S  S S S   S +  S
Sbjct: 597  DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDS 656

Query: 2131 SGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGS 2190
            S      + S  S   +   SSS S S      S S  SS        S  S S     S
Sbjct: 657  SDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS 716

Query: 2191 GSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ 2250
             S +S+S     S S  SS        S +SS     +S     S+ S   S S    + 
Sbjct: 717  DSSNSNSSDSDSSNSSDSSD-------SSNSS-----DSSDSSDSSNSSDSSDSSDSSNS 764

Query: 2251 GQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSG 2310
                 +S  S + D   SS    SS+    S SS SS        S  S S     S S 
Sbjct: 765  SDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSS 824

Query: 2311 HSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQH 2370
             SS+       S  S SS    S  G  S   +   SS  S       S +   SS    
Sbjct: 825  DSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD 884

Query: 2371 GSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQ 2430
             + S  SS      +SS S SS   + S S  S       S S  S   S     S S  
Sbjct: 885  SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDS-------SNSSDSSESSNSSDNSNSSD 937

Query: 2431 SSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG 2490
            SS+ S     S  S+S     S S +SS   +    S  +S      S+S  SS      
Sbjct: 938  SSNSSDSSDSSDSSNS-----SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992

Query: 2491 STSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPS 2550
             +S  S S     +S    SS   + S SS SS        S  S       S      S
Sbjct: 993  DSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052

Query: 2551 YGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS 2610
               + S S  SS S         S      ESS    SS S   S S  SS        S
Sbjct: 1053 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1112

Query: 2611 GQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQ 2670
              S   +   SS  S S      S S  SS        S  S S     S     SS   
Sbjct: 1113 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS 1172

Query: 2671 HGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQS 2730
              S S  SS           S      +S     S+ S   S S           +S  +
Sbjct: 1173 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSN 1232

Query: 2731 STFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGS 2790
             + D   SS    SS     S SS SS           S S   +G+ +G  S     GS
Sbjct: 1233 ESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGS 1292

Query: 2791 GSGQSS 2796
             S  S+
Sbjct: 1293 DSNHST 1298



 Score =  242 bits (618), Expect = 3e-63
 Identities = 264/1140 (23%), Positives = 367/1140 (32%), Gaps = 36/1140 (3%)

Query: 20   TQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQSLDRDHNKKVDFTEYL---- 75
            TQ+G+       E   +++ +  Q+  + N  D  D I+++  R+     + T  +    
Sbjct: 162  TQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKR 221

Query: 76   --LMIFKLVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWS 133
                  ++     +  G D    S S    D  + +   ++ ++E    ++SS ++S   
Sbjct: 222  NGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSS-NNSKGQ 280

Query: 134  AGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRG 193
             G++     +   S+  G  S S+           HN   G  +S  E+NS         
Sbjct: 281  EGQDHGKEDDHDSSI--GQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGS 338

Query: 194  QCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGH 253
            Q    + +  +       +  +  ++TH  G  Q  G      SSG  +   + G G+  
Sbjct: 339  QRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEG 398

Query: 254  SSGYGQHGSRSGQSS----------RGERHRSSSGSSSSYGQHGSGSR-----------Q 292
                GQHG   G+ +           G   +S  G+   +   GS S            +
Sbjct: 399  KEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDK 458

Query: 293  SLGHGRQGSGSRQSPSHVRHGSGSGHSSSHG--QHGSGSSYSYSRGHYESGSGQTSGFGQ 350
            S+      S    + +   +     +SSS G   + S  S     G    G+        
Sbjct: 459  SMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDST 518

Query: 351  HESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHS 410
             ++ +  S+G   +G+     S  G+  S S  + SS    SS    SS      ++  S
Sbjct: 519  SDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSS 578

Query: 411  SGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHES 470
                  S  S  S       S S  S  S         S SS      S   S     +S
Sbjct: 579  DSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS 638

Query: 471  SSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGH 530
             S+ S   +   S +  SS      + S  S   +   SS+ S SS     S S  S   
Sbjct: 639  KSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNS 698

Query: 531  SRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESR 590
            S     S  S S S    +S +  SS            SS     S S  SS        
Sbjct: 699  SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758

Query: 591  SGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQS-SSHGQHGSGSSQSSRY 649
            S  S+      SS    S+   + S S  SS+      +S  S SS+    S SS SS  
Sbjct: 759  SDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDS 818

Query: 650  GQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQ 709
                S    + S     S+   SS       GS   SSN    S S  SS     S S  
Sbjct: 819  DSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD 878

Query: 710  SSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQG 769
            SS  S   S  S +S      S S  S  S+   SS    SS     S S  SS +    
Sbjct: 879  SSDSSD--SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSS 936

Query: 770  SGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYS 829
              S  S S     SS+   SS+    S +S SS     +S     S      S S     
Sbjct: 937  DSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSD 996

Query: 830  QHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQ 889
               S++   SS     S S  SS S     SS  S S    +S+    S      S S  
Sbjct: 997  SSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSN 1056

Query: 890  SPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGS 949
            S         S  S S     S     SS     S S  SS     S S  SS  +    
Sbjct: 1057 SSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1116

Query: 950  GSGHS-SSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS 1008
             S  S SS     S S  SS S     SS SS S     S            S S  S  
Sbjct: 1117 SSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSD 1176

Query: 1009 PSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGS 1068
             S     S S  SS        S  S S    +S     S      S S  SS   +   
Sbjct: 1177 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSD 1236

Query: 1069 SSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGH 1128
            SS  S +     S+    SS      S     S  Q  SG+  ++G        G    H
Sbjct: 1237 SSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNH 1296



 Score =  225 bits (573), Expect = 6e-58
 Identities = 229/871 (26%), Positives = 291/871 (33%), Gaps = 33/871 (3%)

Query: 118  EENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSS 177
            ++   Q    + S  S G +D+ S +   S   G  S +   S +   +G  +   G   
Sbjct: 456  DDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYN---SDESKDNGNGSDSKGAED 512

Query: 178  SYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSS 237
               +  SD++ S   G   +G+  +    +  SG G+S S+D+  S S  SS  S    S
Sbjct: 513  DDSDSTSDTNNSDSNGNGNNGNDDND---KSDSGKGKSDSSDSDSSDSSNSSDSSDSSDS 569

Query: 238  SGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHG 297
                S  S     S   S        S  S+  +   SS  S SS     S S+      
Sbjct: 570  DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS 629

Query: 298  RQGSG-----SRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHE 352
               S      S  S S+    S +  SS      + S  S S    +S S   S      
Sbjct: 630  ESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDS 689

Query: 353  SGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSS-SYGQHESASRHSS 411
            S S  SS  S+    S  S S     S S  ++SS    S+S  SS S    +S+    S
Sbjct: 690  SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS 749

Query: 412  GRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESS 471
                 SS S  S         S  S SS    +     SS+    S S  SS   +   S
Sbjct: 750  SNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS 809

Query: 472  SEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHS 531
            S+ S       S S  SS        S  S   +   SS GS S      S +R    +S
Sbjct: 810  SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD-----SSNRSDSSNS 864

Query: 532  RHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRS 591
               S S  S + S     S S +SS+       S  S S     S S  SS   +    S
Sbjct: 865  SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS 924

Query: 592  GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQ 651
              S+      SS   +S+     S S  SS       +S  S S   + S SS SS    
Sbjct: 925  ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD 984

Query: 652  QGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSS 711
                S  S S     SD  +SS        S   SSN    S S  SS     S S  SS
Sbjct: 985  SSDSSDSSDS--SDSSDSSNSSDSSDSSDSS--DSSNSSDSSNSSDSSNSSDSSDSSDSS 1040

Query: 712  GYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSG 771
              S   S SS SS        S  S  S+   SS    SS     S S  SS        
Sbjct: 1041 D-SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDS 1099

Query: 772  SGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQH 831
            S  S S     SS    SS   + S +S SS        S  +      ES         
Sbjct: 1100 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSD---- 1155

Query: 832  GSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSP 891
                   SS     S S  SS S     SS  S S    +S+    S      S S  S 
Sbjct: 1156 -------SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1208

Query: 892  GHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGS 951
                    S  S S     S     SS     S S  SS     S S  SS  T   +  
Sbjct: 1209 DSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDE 1268

Query: 952  GHSSSYEQHGSRSGQSSRSEQHGSSSGSSSS 982
              S S   +G+ +G  S S+  GS S  S+S
Sbjct: 1269 SDSQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299



 Score =  212 bits (539), Expect = 5e-54
 Identities = 219/861 (25%), Positives = 295/861 (34%), Gaps = 24/861 (2%)

Query: 103  DDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQ 162
            DD     ++   +++       +S S ++ S+  + SY+ +       G++S        
Sbjct: 456  DDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDS 515

Query: 163  RDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHG 222
               S  +NS S  + + G  ++D    SG+G+  S    S +   + S S  SS +D+  
Sbjct: 516  DSTSDTNNSDSNGNGNNGNDDNDK-SDSGKGKSDSSDSDSSD-SSNSSDSSDSSDSDSSD 573

Query: 223  SGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSS 282
            S S   S  S   SS    S  S   S S  SS        S  S   +    SS S S 
Sbjct: 574  SNSSSDSDSSDSDSSDSSDSD-SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632

Query: 283  YGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGS 342
                 S S  S  +    S +  S       + S  S S     S SS   S     S S
Sbjct: 633  SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692

Query: 343  GQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQ 402
              +S   +    S  S   S   S S +S+S     S S  +S S     SS  S S   
Sbjct: 693  SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNS 752

Query: 403  HESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYS 462
             +S+    S     SS S  S       + S  + SS    +    +SS     S S  S
Sbjct: 753  SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDS 812

Query: 463  SGFGHHESSSEHSSGYTQHGSGSGHSS-----GHGQHGSRSGQSSRGERQGSSAGSSSSY 517
            S     +SS+   S  +   S S +SS          GS S  S+R +   SS  S SS 
Sbjct: 813  SDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD 872

Query: 518  GQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESG 577
              + S S  S   S   S S  S   S       S  S+S       +   SS     S 
Sbjct: 873  SSNSSDSSDS-SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931

Query: 578  SGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHG 637
            + +SS   +    S  S       SS+   S++    S S  S S     ++    SS  
Sbjct: 932  NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS 991

Query: 638  QHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSS--SNGPHGSVS 695
               S SS SS        S  S S     S     SS     S S  SS  S+    S S
Sbjct: 992  SDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1051

Query: 696  GQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQH 755
              SS     S S  SS  S   S SS SS   +    S  S+ S+   SS    SS    
Sbjct: 1052 SDSSNSSDSSDSSDSSD-SSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSD 1110

Query: 756  GSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQAS 815
             S S  SS        S  S S     SS+   SS     S +S SS        S  + 
Sbjct: 1111 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSD 1170

Query: 816  GFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASH 875
                 +S +    S    +S   SS     S S  SS S     SS  S S    +S+  
Sbjct: 1171 SSDSSDSSNSSDSSDSSDSSD--SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1228

Query: 876  HASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHK 935
              S      S S  S         S  S S       +  S S  + G+G          
Sbjct: 1229 SDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNG---------- 1278

Query: 936  SSSGQSSGYTQHGSGSGHSSS 956
            +++G  S     GS S HS+S
Sbjct: 1279 NNNGSDSDSDSEGSDSNHSTS 1299



 Score =  188 bits (478), Expect = 6e-47
 Identities = 197/781 (25%), Positives = 267/781 (34%), Gaps = 21/781 (2%)

Query: 97   SGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRG----SLKPGT 152
            +G+   DD  +    + +++  ++   +SS S  S  + ++DS   N       S    +
Sbjct: 529  NGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSS 588

Query: 153  ESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGS 212
            +S     S   + S   +S     SS    +SDS   S + +  S    S +     + S
Sbjct: 589  DSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS 648

Query: 213  GQS-------SSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSG 265
              S       SSN ++ S S  SS  S   SSS  S+  S   S S  SS   +    S 
Sbjct: 649  DSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN--SSDSSDSSDSSNSSESSDSSD 706

Query: 266  QSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQH 325
             S       S S +S+S     S S  S         S  S S   + S S  SS     
Sbjct: 707  SSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS--SNSSDSSDSSDSSNS 764

Query: 326  GSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQAS 385
               S  S S    +S +   S    + S S  SS  S   + S  S S     S S  +S
Sbjct: 765  SDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSS 824

Query: 386  SSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTG 445
             S     SS  S+S    +S S  S G    SS    S         S  S SS    + 
Sbjct: 825  DSSNSSDSSDSSNSSDSSDS-SDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS 883

Query: 446  FGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGE 505
                SS+    S S  SS     +SS+   S  + + S S  SS    + + S  S+  +
Sbjct: 884  DSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD 943

Query: 506  RQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGS 565
               SS  S+SS   + S S  S   S   S      S S    +S     SS       S
Sbjct: 944  SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003

Query: 566  GRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQ 625
              SS        S  S      +S +   S      S S  SS       +S  S S   
Sbjct: 1004 SDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1063

Query: 626  HGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWS 685
              ++    SS     S SS+SS      + S  S S     S    S S     S     
Sbjct: 1064 SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDS----SDSSDSSDSSDSSD 1119

Query: 686  SSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSS 745
            SSN    S S  SS     S S  SS  S   S SS SS        S  S  S+   SS
Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSD-SSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1178

Query: 746  SGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCG 805
            +   SS     S S  SS        S  S S     SS    SS     S ++ SS   
Sbjct: 1179 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSS 1238

Query: 806  HYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSS 865
                 S  ++     +S      +   +      S+  +G+ +G  S S    S S  S+
Sbjct: 1239 DSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHST 1298

Query: 866  S 866
            S
Sbjct: 1299 S 1299



 Score =  187 bits (474), Expect = 2e-46
 Identities = 188/713 (26%), Positives = 243/713 (34%), Gaps = 8/713 (1%)

Query: 92   DYCQVSGSKLRDDTHQHQEEQEETEKEENKRQES-SFSHSSWSAGENDSYSRNVRGSLKP 150
            D    S S    D+    +  + ++  ++K   S S S SS S  ++DS   N   S   
Sbjct: 594  DSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDN 653

Query: 151  GTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGS 210
               S S   S   D S   +S    SSS    +SDS  SS        S  S +     S
Sbjct: 654  SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS 713

Query: 211  GSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRG 270
             S  SS++++  S S  SS  S   +SS  S       S     S    + S S  SS  
Sbjct: 714  DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 773

Query: 271  ERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSS 330
                 SS SS S     S       +    S S  S            +SS   + S SS
Sbjct: 774  SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833

Query: 331  YSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQH 390
             S +       S  + G     S    SS  S     S  S+S     S+    SS+   
Sbjct: 834  DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893

Query: 391  GSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSS 450
             S S  SS     +S++   S    +SS S +S       + S  S SS    +    +S
Sbjct: 894  SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS 953

Query: 451  SSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSS 510
            S     S S  SS      SS    S  +   S S  SS        S  S   +   SS
Sbjct: 954  SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013

Query: 511  AGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSS 570
              S+SS   + S S  S   S   S S  S   S     S S  SS        S  S S
Sbjct: 1014 DSSNSSDSSNSSDSSNS-SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1072

Query: 571  RGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATS 630
                +S     S      S S  SS      S S  SS       +S  S S     ++ 
Sbjct: 1073 SDSSDSSDSSESSDSSDSSNSSDSS----DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1128

Query: 631  GQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGP 690
               SS     S SS SS   +    S  S S     S     SS     S S   SS+  
Sbjct: 1129 SSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS-DSSDSS 1187

Query: 691  HGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSS 750
              S S  SS     S S  SS  S   S SS SS        S  +  S+   SS    S
Sbjct: 1188 DSSDSSDSSDSSDSSDSSDSSD-SSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDS 1246

Query: 751  SYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSS 803
            S     S S  SS      +    S S+  +G+++G  S     GS ++ S+S
Sbjct: 1247 SNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299



 Score = 41.6 bits (96), Expect = 0.011
 Identities = 35/160 (21%), Positives = 56/160 (35%), Gaps = 2/160 (1%)

Query: 86   NKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVR 145
            N     D  + S S    D+    +  + ++  ++    +S   S  S   + S S +  
Sbjct: 1140 NSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1199

Query: 146  GSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNY 205
             S      S S   S   D S   +S     S+    +SDS  SS        S  S + 
Sbjct: 1200 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSS 1259

Query: 206  GQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYS 245
                  + +S S     SG+G ++G      S G  S +S
Sbjct: 1260 DSTSDSNDESDSQSK--SGNGNNNGSDSDSDSEGSDSNHS 1297



 Score = 36.6 bits (83), Expect = 0.36
 Identities = 55/274 (20%), Positives = 96/274 (35%), Gaps = 48/274 (17%)

Query: 2608 SRSGQSSRGERHGSS----SGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLG 2663
            +RS  S + E + S     SG   H G  G       GH  +G+GS  +   G+  S   
Sbjct: 38   ARSNVSVQDELNASGTIKESGVLVHEGDRGRQENTQDGHKGEGNGSKWAEVGGKSFST-- 95

Query: 2664 HSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHES-----------------------G 2700
            +S+   + G+  G +   G  E+  GH  + G+ E+                        
Sbjct: 96   YSTLANEEGNIEGWNGDTGKAET-YGHDGIHGKEENITANGIQGQVSIIDNAGATNRSNT 154

Query: 2701 SGHSSAYSQHGS--GSGHFCS-----------QGQHGSTSGQSSTFDQEGSSTGQSSSYG 2747
            +G++   +Q+G    +GH               G + ST  +    +    + G +S   
Sbjct: 155  NGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEIT 214

Query: 2748 HRGSGSSQSSGYGRHGAGSGQSLS-HGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSG 2806
             + +     +       G+G+        GS SG  +   +   GSG         +G+G
Sbjct: 215  PQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDED-EGSGDDE---DEEAGNG 270

Query: 2807 QDGYSYCKGGSNHDGGSSGSYFLSFPSSTSPYEY 2840
            +D  +  KG    D G    +  S   ++   EY
Sbjct: 271  KDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEY 304


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score =  219 bits (557), Expect = 4e-56
 Identities = 643/2887 (22%), Positives = 1036/2887 (35%), Gaps = 362/2887 (12%)

Query: 123  QESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSY---SGQSSSY 179
            QES+ SHSS S   + + S     +L  G ES +    F  +    H +    S  SS  
Sbjct: 1048 QESTTSHSS-SGSTDTALSPGSTTALSFGQESTT----FHSNPGSTHTTLFPDSTTSSGI 1102

Query: 180  GEQNSDSHQSSG--RGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSS 237
             E ++  H S+G  R      S  SP         G+S++  TH + +  +       ++
Sbjct: 1103 VEASTRVHSSTGSPRTTLSPASSTSPGL------QGESTAFQTHPASTHTTPSPPSTATA 1156

Query: 238  SGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHG 297
              + S       GS  ++ +    + SG S +     SS  +S   G   S +  +    
Sbjct: 1157 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS---GTTPSSAHSTTSGR 1213

Query: 298  RQGSGSRQSPSHVRHGSGSGHSSSHG-QHGSGSSYSYSRGHYESGSGQTSGFGQHESGSG 356
             + + SR SP      +  G +++ G    S + YS  R    S +   S       G G
Sbjct: 1214 GESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPR----SPTTTLSPASMTSLGVG 1269

Query: 357  QSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSS-----------SYGQHES 405
            + S  S+   GS HS+      +T G +  S    SSSR S+           S    E 
Sbjct: 1270 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEP 1329

Query: 406  ASRHSSGRGQHSS---GSGQSPGHGQRGSGSGQSPSSGQHG-------TGFGRSSSSGPY 455
             + HS     H++       + G  +  +    SP+S Q G          G  S++ P 
Sbjct: 1330 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPS 1389

Query: 456  VSGS---------GYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGER 506
             SGS           +SG     + S  S   T+  +  G S        +S       R
Sbjct: 1390 SSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPG-SPTTPSLSEKSTTFYTSPR 1448

Query: 507  QGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSG 566
               +  S ++    G     S  HS+ GS      + +    +S +    S  P    S 
Sbjct: 1449 SPDATLSPATTTSSGVSEESSTSHSQPGS------THTTAFPDSTTTSDLSQEPTTSHSS 1502

Query: 567  RSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQ--------------HGSSSGHSSTHGQ 612
            + S+      GS  +S LG Q +    S G  +                S+  HSST   
Sbjct: 1503 QGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSL 1562

Query: 613  HGS-TSGQSSSCG-QHGATSGQS--SSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSD 668
            H + T   S+S G Q  +T+ QS  SS     S    ++   +  +     PS       
Sbjct: 1563 HTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHF 1622

Query: 669  FGHSSSYGQHGSGSGWSSSNGPHGSV-----SGQSSGFGHKSGSGQSSGYSQHGS--GSS 721
               S++ G+    +   SS G  G+      S  S   G  + S  SSG ++  +  GS+
Sbjct: 1623 SASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGST 1682

Query: 722  HSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSG--SGHSPSRV 779
             ++G  +  +    S RS     S   ++S    G     ++ H R GS   +    S  
Sbjct: 1683 TTAGLSEKSTTFYSSPRSPDTTLSPASTTS---SGVSEESTTSHSRPGSTHTTAFPGSTT 1739

Query: 780  RHGSSSGHSSSHGQHGS-------GTSCSSSCG------HYESGSGQASGFGQHESGSGQ 826
              G S   ++SH   GS       G++ +SS G      H   GS + +    + + SG 
Sbjct: 1740 MPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGL 1799

Query: 827  GYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQS---------------SSYGQHE 871
                  S   H S+   H + S   S++ Q +S++ QS               S++ +  
Sbjct: 1800 ---LEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELS 1856

Query: 872  SASHHA--SGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQS 929
            + SH +  S    H S S  + G  +  +    SP          RS++SG       +S
Sbjct: 1857 TTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGL----VEES 1912

Query: 930  SGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSG 989
            + +     S Q+  + +  + SG S       S +  +  S    +S+        H S 
Sbjct: 1913 TAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSP 1972

Query: 990  SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSG---WSSSRGPYESGSGH 1046
               +  H    S +      S   H S     +   P RS +      S+  P  SGS  
Sbjct: 1973 GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSME 2032

Query: 1047 SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHG 1106
            ++ L    +  G S       S++ HSS      +T+   +S    G S   ++SH + G
Sbjct: 2033 TTALPGSTTTPGLSEK-----STTFHSSPRSP--ATTLSPASTTSSGVSEESTTSHSRPG 2085

Query: 1107 S-------GSSQSSGYGRQGSGSGQSPGHGQR----GSGSRQSPSYGRHGSGSGRSSSSG 1155
            S        S+ + G  R  + S  SPG         S +   PS     S S   S+  
Sbjct: 2086 STHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDT 2145

Query: 1156 QHGSGLGESSGFGHHESSSGQSSSYSQHGS---GSGHSSGYGQHGSRSGQSSRGERHGSS 1212
                G   +  FG  ES++  SS  S H +    S  SSG  +  +R   S+   R   S
Sbjct: 2146 ALSPGSTTALSFGQ-ESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS 2204

Query: 1213 SGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRG 1272
              SS+  G  G    +S+      + +  +PS     +     S+      GS  ++   
Sbjct: 2205 PASSTSPGLQG----ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFP 2260

Query: 1273 PYESRSGHS---SVFGQHESGSGH--SSAYSQHGSGSGHFCSQGQHGSTS-----GQSST 1322
               + SGHS   ++F      SG   SSA+S          S+   GST      G ++T
Sbjct: 2261 ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTT 2320

Query: 1323 FDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGS 1382
                G S   ++ Y    S ++  S       G G+  +  R   GS HS+      +  
Sbjct: 2321 ---PGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTP 2377

Query: 1383 GWSSSSGRHGS---GSGQSSGFGHHESSSWQSSGCTQHGS--GSGHSSSYEQHGSRSGQS 1437
            G S  S    S   GS +++ F    ++S +    T   S   S H++ + +  + SG +
Sbjct: 2378 GLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLT 2437

Query: 1438 SRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPY 1497
                    S  S+ +      G   +L     G  S   PS S G  G+    + S +  
Sbjct: 2438 EESTAFPGSPASTQT------GLPATLTTADLGEESTTFPSSS-GSTGTTLSPARSTTSG 2490

Query: 1498 GSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSS 1557
              G    S   P  + ++   G     S S +S+ +  + S     +T     +TS    
Sbjct: 2491 LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTF--YTSPRSPDATLSPATTTSS--- 2545

Query: 1558 SCGQHGASSGQSSSHGQHGS-------GSSQSSGYGRQGSGSGQSPGHGQR----GSGSR 1606
                 G S   S+SH Q GS        S+ + G  R  + S  SPG         S + 
Sbjct: 2546 -----GVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT 2600

Query: 1607 QSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGS---GSGHSSGY 1663
              PS     S S   S+      G   +  FG  ES++  SS  S H +    S  SSG 
Sbjct: 2601 SGPSQESTTSHSSPGSTDTALSPGSTTALSFGQ-ESTTFHSSPGSTHTTLFPDSTTSSGI 2659

Query: 1664 GQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLG 1723
             +  +R   S+   R   S  SS+  G  G    +S+      + +  +PS     +   
Sbjct: 2660 VEASTRVHSSTGSPRTTLSPASSTSPGLQG----ESTTFQTHPASTHTTPSPPSTATAPV 2715

Query: 1724 HSSSHGQHGSGSGRSSSRGPYESRSGHS---SVFGQHESGSGH--SSAYSQHGSGSGHFC 1778
              S+      GS  ++      + SGHS   ++F      SG   SSA+S          
Sbjct: 2716 EESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT 2775

Query: 1779 SQGQHGSTS-----GQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRG 1833
            S+   GST      G ++T    G S   ++ +    S ++  S       G G+  +  
Sbjct: 2776 SRISPGSTEITTLPGSTTT---PGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTS 2832

Query: 1834 RHGSGSGHSSSYGQHGSGSGWSSSSGRHGS---GSGQSSGFGHHESSSWQSSGYTQHGS- 1889
            R   GS HS+      +  G S  S    S   GS +++ F    ++S +    T   S 
Sbjct: 2833 RSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSR 2892

Query: 1890 -GSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS 1948
              S H++ + +  + SG +        S  S+ +      G   +L     G  S   PS
Sbjct: 2893 PASTHTTLFTEDSTTSGLTEESTAFPGSPASTQT------GLPATLTTADLGEESTTFPS 2946

Query: 1949 PSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGS 2008
             S G  G+    + S      G    S   P  + +    G     S S +S+ +     
Sbjct: 2947 SS-GSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTF----- 3000

Query: 2009 SSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP-- 2066
                  T  +   A+   ++    G S   S+SH Q GS  + +       SG  Q P  
Sbjct: 3001 -----YTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTA 3055

Query: 2067 GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSG--QSSSYSQHG 2124
             H  +GS            S  G+ S++    PG  E++       +SG  ++S+ +   
Sbjct: 3056 SHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSS 3115

Query: 2125 SGSGHSSGYGQHGSRSGQSSRGERHGS-SSGSSSRYGQHGSGSR----QSSGHGRQGSG- 2178
            +GS H++      + +G         S  S S +     G+ +      ++ H R  S  
Sbjct: 3116 TGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTP 3175

Query: 2179 ----SGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQH-----ES 2229
                S  S + GR    +   SS G  G+          + +RS  S + G+       S
Sbjct: 3176 TTHFSASSTTLGRSEESTTVHSSPGATGTAL--------FPTRSATSVLVGEPTTSPISS 3227

Query: 2230 GSGHSSAYSQHGSGSG------HFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGS-- 2281
            GS  ++A     + +G       F S  +   T+   ++    G S   ++SH + GS  
Sbjct: 3228 GSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTH 3287

Query: 2282 -----GSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 2336
                 GS+      Q+ + S  SP     GS     S      S  G  S++   G GS 
Sbjct: 3288 TTAFPGSTTMPGVSQESTASHSSP-----GSTDTTLSPGSTTASSLGPESTTFHSGPGST 3342

Query: 2337 QSSGFGHHESSSW--QSSGYTQHGSGSGHSS-SYEQHGSRSGQSSRGERHGSSSGSSS-- 2391
            +++    + ++S   ++S      +GS H++ S     +R G+S+  +   +S  ++   
Sbjct: 3343 ETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAP 3402

Query: 2392 ----------SYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSG- 2440
                      S   HGS S     H    S +      S   H S    +++ SP  S  
Sbjct: 3403 PTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT 3462

Query: 2441 SGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG 2500
            SG       Y S  G +  +   ES +  +SG G+  ++S  S+TH    + S  S+   
Sbjct: 3463 SGLVEESTTYHSSPGSTQTMHFPESDT--TSGRGEESTTSHSSTTHTISSAPSTTSALVE 3520

Query: 2501 QHGA-SSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG 2559
            +  +  S   S+   H   SS +SG   + + S  S    Q  +G+   P+        G
Sbjct: 3521 EPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS----QDATGTIVLPARSTTSVLLG 3576

Query: 2560 RSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERH 2619
             S++S    SG  E++      ++ G S       S + HSS       RS  ++     
Sbjct: 3577 ESTTS-PISSGSMETTALPGSTTTPGLSEK-----STTFHSS------PRSPATTLSPAS 3624

Query: 2620 GSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSS 2679
             +SSG S       S SR  S H      S  +P   RH +     +SH   GS     +
Sbjct: 3625 TTSSGVSEE--STTSHSRPGSTHTTAFPDSTTTPGLSRHST-----TSHSSPGS---TDT 3674

Query: 2680 SRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSS 2739
            +  P  +    SS     ES + HSS+                 GST    S       S
Sbjct: 3675 TLLPASTTTSGSS----QESTTSHSSS-----------------GSTDTALSPGSTTALS 3713

Query: 2740 TGQSSSYGHRGSGSSQSSGYGRHGAGSG----QSLSHGRHGSGSGQSSSYGQHGSG-SGQ 2794
             GQ S+  H   GS+ ++ +      SG     +  H   GS     S       G  G+
Sbjct: 3714 FGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGE 3773

Query: 2795 SSGYSQH 2801
            S+ +  H
Sbjct: 3774 STAFQTH 3780



 Score =  216 bits (551), Expect = 2e-55
 Identities = 662/2989 (22%), Positives = 1069/2989 (35%), Gaps = 491/2989 (16%)

Query: 123  QESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLS---FQRDFSGQHNSYSGQSSSY 179
            QE S +  SW +  + + S        PGT +    +S     R  S     +S  S++ 
Sbjct: 1577 QEESTTFQSWPSSSDTTPS-------PPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTL 1629

Query: 180  GEQNSDSHQSSGRGQCGSG-----SGQSPNYGQHGSGSGQSSSNDTHG-SGSGQSSGFSQ 233
            G     +   S  G  G+      S  S   G+  +    S S +T    GS  ++G S+
Sbjct: 1630 GRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSE 1689

Query: 234  HKSS---------------SGQSSGYSQHGS------GSGHSSGYGQHGSRSGQSSRGER 272
              ++               S  SSG S+  +      GS H++ +    +  G S     
Sbjct: 1690 KSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTA 1749

Query: 273  HRSSSGSSSSYGQHGSGSRQSLG------HGRQGS-------------GSRQSPSHVRHG 313
              SS GS+ +    GS +  SLG      H   GS             G  ++ + V   
Sbjct: 1750 SHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSS 1809

Query: 314  SGSGHSS--------SHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGS--GQSSGYSK 363
            +GS H++          G+  +  S+  S+    +    TS F +  + S    SS  + 
Sbjct: 1810 TGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTT 1869

Query: 364  HGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQS 423
            H S S  +  + +  +T   +  +     S  +S++ G  E ++ + S     S GS Q+
Sbjct: 1870 HFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHS-----SPGSTQT 1924

Query: 424  PGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGS 483
                +  + SG+S  S    +    + SS P  + +       +H S     S  T H  
Sbjct: 1925 MHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPG---STATTHFP 1981

Query: 484  GSGHSSGHGQHG--SRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSP 541
             S  +SG  +    S S Q + G     +  ++S      + S  S G     +  G + 
Sbjct: 1982 DSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTT 2041

Query: 542  SPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHG 601
            +P     +S +  SS   P    S  S++     SG    S   H    S  ++ +    
Sbjct: 2042 TPGLSE-KSTTFHSSPRSPATTLSPASTT----SSGVSEESTTSHSRPGSTHTTAFPDST 2096

Query: 602  SSSG---HSST-HGQHGSTSGQ--SSSCGQHGATSGQSSSHGQHGS-------GSSQSSR 648
            ++ G   HS+T H   GST      +S    G +   ++SH   GS       GS+ +  
Sbjct: 2097 TTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALS 2156

Query: 649  YGQQGSGSGQSPSRGRHGSDFGHS--SSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSG 706
            +GQ+ +    SP    H + F  S  SS     S    SS+  P  ++S  SS       
Sbjct: 2157 FGQESTTFHSSPG-STHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASST--SPGL 2213

Query: 707  SGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHG 766
             G+S+ +  H + S+H++      + +     +  H S     ++   H   S  +SGH 
Sbjct: 2214 QGESTAFQTHPA-STHTTPSPPSTATAPVEESTTYHRSPGSTPTT---HFPASSTTSGHS 2269

Query: 767  RQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYE----SGSGQASGFGQHES 822
             + +    SP       SS HS++ G+ G  T+   S G  E     GS    G  +   
Sbjct: 2270 EKSTIFHSSPDASGTTPSSAHSTTSGR-GESTTSRISPGSTEITTLPGSTTTPGLSE--- 2325

Query: 823  GSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGR 882
                       AS  F S  R  +T+   S +       G+ S+  + +  S H++    
Sbjct: 2326 -----------ASTTFYSSPRSPTTT--LSPASMTSLGVGEESTTSRSQPGSTHSTV--- 2369

Query: 883  HGSGSGQSPGHGQRGS-------GSGQSPSYGRHGSGS--GRSSSSGRHGSGSGQSSGFG 933
                S  +PG  +  +       GS ++  + R  + S  G   ++      S  ++ F 
Sbjct: 2370 -SPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFT 2428

Query: 934  HKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRS--EQHGSSSGSSSSYGQHGSGSR 991
              S++   SG T+  +    S +  Q G  +  ++    E+  +   SS S G   S +R
Sbjct: 2429 EDSTT---SGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPAR 2485

Query: 992  QSL-GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGP---------YE 1041
             +  G     + S  SPS +      GS  + S    +S + ++S R P           
Sbjct: 2486 STTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSE-KSTTFYTSPRSPDATLSPATTTS 2544

Query: 1042 SGSGHSSGLGHRESRSGQSSGYGQHGSSSG---HSST-HGQHGSTSGQ--SSSCGQHGAS 1095
            SG    S   H +  S  ++ +    ++ G   HS+T H   GST      +S    G S
Sbjct: 2545 SGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPS 2604

Query: 1096 SGQSSSHGQHGS-------GSSQSSGYGRQGSGSGQSPGH--------GQRGSGSRQSPS 1140
               ++SH   GS       GS+ +  +G++ +    SPG             SG  ++ +
Sbjct: 2605 QESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAST 2664

Query: 1141 YGRHGSGSGRS--SSSGQHGSGL-GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHG 1197
                 +GS R+  S +     GL GES+ F  H +S+  + S     +     S      
Sbjct: 2665 RVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRS 2724

Query: 1198 SRSGQSSRGERHGSSSGSSS-----HYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGL 1252
              S  ++      ++SG S      H     SG+  SS H         + SR   GS  
Sbjct: 2725 PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE 2784

Query: 1253 -----GHSSSHG-QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGH 1306
                 G +++ G    S +  SS R P  + S  S        G G  S  S+   GS H
Sbjct: 2785 ITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMT----SLGVGEESTTSRSQPGSTH 2840

Query: 1307 FCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGS--GQSPSRGR 1364
                    +T G S     E S+T  SSS      GS++++ + R    S  G+ P+   
Sbjct: 2841 STVSPASTTTPGLS-----EESTTVYSSS-----PGSTETTVFPRSTTTSVRGEEPTTFH 2890

Query: 1365 HGSGSGHSSSYGQHGSGSG----------------------------------WSSSSGR 1390
                S H++ + +  + SG                                  + SSSG 
Sbjct: 2891 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGS 2950

Query: 1391 HGS----GSGQSSGFGHHESSSWQSSGCTQHGS--GSGHSSSYEQHGS------RSGQSS 1438
             G+        +SG     + S  S   T+  +  GS  + S  +  +      RS  ++
Sbjct: 2951 TGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 3010

Query: 1439 RGERHGSSSG----SSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY 1494
                  +SSG    SS+S+ Q GS    +       SG  Q P+ S    GS     S  
Sbjct: 3011 LSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPG 3070

Query: 1495 SPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSG 1554
            S   S  G  S+      G + ++ L      SG         S+  HSST   H + + 
Sbjct: 3071 STTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEA-----STPTHSSTGSLHTTLTP 3125

Query: 1555 QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSG------SRQS 1608
             SS+    G     ++      S  +  S  G   +    S  +  R S       S  S
Sbjct: 3126 ASSTSA--GLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASS 3183

Query: 1609 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS---GQSSSYSQHGSGSGHSSGYGQ 1665
             + GR    +   SS G  G+ L     F    ++S   G+ ++ S   SGS  ++    
Sbjct: 3184 TTLGRSEESTTVHSSPGATGTAL-----FPTRSATSVLVGEPTT-SPISSGSTETTALPG 3237

Query: 1666 HGSRSGQSSRGERHGSSSRSS------SRYGQHGSGSRQSSGHGRQGS-------GSGQS 1712
              + +G S +     SS RS       +     G     ++ H R GS       GS   
Sbjct: 3238 STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTM 3297

Query: 1713 PSRGRHGSGLGHSSSHGQHGS-------GSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 1765
            P     G     ++SH   GS       GS  +SS GP ES + HS        GS  ++
Sbjct: 3298 P-----GVSQESTASHSSPGSTDTTLSPGSTTASSLGP-ESTTFHSG------PGSTETT 3345

Query: 1766 AYSQHGSGSGHF-CSQGQHGSTSGQSSTFDQEGSSTGQ---------------------- 1802
                + + SG    S   H ST    +T    GS+T Q                      
Sbjct: 3346 LLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTT 3405

Query: 1803 --------SSSHGQ-------HGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQ 1847
                    ++SHG        H S SS +    ++ +    SP           S++ G 
Sbjct: 3406 TSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGL 3465

Query: 1848 HGSGSGWSSSSGR----HGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGS- 1902
                + + SS G     H   S  +SG G   ++S  S+ +T   + S  S+  E+  S 
Sbjct: 3466 VEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSY 3525

Query: 1903 RSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSS 1962
             S   S    H   S ++S   +  + S  S         +G    P+R       G+S+
Sbjct: 3526 HSSPGSTATTHFPDSSTTSGRSEESTASHSSQ------DATGTIVLPARSTTSVLLGEST 3579

Query: 1963 SYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSA 2022
            +               P  SGS  ++ L    +  G S       S++ HSS      + 
Sbjct: 3580 T--------------SPISSGSMETTALPGSTTTPGLSEK-----STTFHSSPRSPATTL 3620

Query: 2023 SGQSSSCGQHGASSGQSSSHGQHGS-------GSSQSSGYGRQGSGSGQSPGH------- 2068
            S  S++    G S   ++SH + GS        S+ + G  R  + S  SPG        
Sbjct: 3621 SPASTTSS--GVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP 3678

Query: 2069 -GQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGS-- 2125
                 SGS Q  +     SGS  ++ S    PG   +  FG  ES++  SS  S H +  
Sbjct: 3679 ASTTTSGSSQESTTSHSSSGSTDTALS----PGSTTALSFGQ-ESTTFHSSPGSTHTTLF 3733

Query: 2126 -GSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPS 2184
              S  SSG  +  +R   S+   R   S  SS+  G  G    +S+      + +  +PS
Sbjct: 3734 PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQG----ESTAFQTHPASTHTTPS 3789

Query: 2185 RGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHS---SVFGQHESGSGH--SSAYSQ 2239
                 +     S+      GS  ++      + SGHS   ++F      SG   SSA+S 
Sbjct: 3790 PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHST 3849

Query: 2240 HGSGSGHFCSQGQHGSTS-----GQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGS 2294
                     S+   GST      G ++T    G S   ++ +    S ++  S       
Sbjct: 3850 TSGRGESTTSRISPGSTEITTLPGSTTT---PGLSEASTTFYSSPRSPTTTLSPASMTSL 3906

Query: 2295 GSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS---GSGQSSGFGHHESSSWQS 2351
            G G+  +  R   GS HS+      +  G S  S    S   GS +++ F    ++S + 
Sbjct: 3907 GVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRR 3966

Query: 2352 SGYTQHGS--GSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQ- 2408
               T   S   S H++ + +  + SG +        S  S+ + G   + +   LG    
Sbjct: 3967 EEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQT-GLPATLTTADLGEEST 4025

Query: 2409 ---HGSGS-GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRG-PYESGSGHSSGLGHR 2463
                 SGS G   SP+R       G+S+      S +  ++  G P        S   + 
Sbjct: 4026 TFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYT 4085

Query: 2464 ESRSGQSSGYGQHGSSSG----HSSTHGQHGSTSGQS--SSCGQHGASSGQSSSHGQHGS 2517
              RS  ++      +SSG     S++H Q GST   +   S    G S   ++SH   GS
Sbjct: 4086 SPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGS 4145

Query: 2518 -------GSSQSSGYGRQGSGSGQSPGHGQR----------GSGSRQSPSYGRHGSGSGR 2560
                   GS+ +S  G+Q +    SPG  +           G     +P++   GS    
Sbjct: 4146 TEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTT 4205

Query: 2561 SSSSGQHGSGLGE-SSGFGHHESSSGQ----------------------SSSYSQHGSGS 2597
             + +    +GL E S+ F    SSS                        SS+ + H S S
Sbjct: 4206 LTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSAS 4265

Query: 2598 GHSSGYGQHGS--RSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSR 2655
              + G  +  +   S   + G     +  ++S      + S  SSG     +  G + + 
Sbjct: 4266 STTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTA 4325

Query: 2656 GRHGSGLGHSSSHGQHG---SGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAY----S 2708
            G         SS        S +  +SS    ES   HS        GS H++A+    +
Sbjct: 4326 GLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS------RPGSMHTTAFPSSTT 4379

Query: 2709 QHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSS 2757
              G       S    GST    S      SS G  S+  H   GS++++
Sbjct: 4380 MPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETT 4428



 Score =  209 bits (531), Expect = 4e-53
 Identities = 664/2967 (22%), Positives = 1052/2967 (35%), Gaps = 401/2967 (13%)

Query: 123  QESSFSHS-SWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGE 181
            QES+ SHS   S     S       SL P + +      + +      N+    +S   E
Sbjct: 334  QESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNT---TTSGLLE 390

Query: 182  QNSDSHQSSGRGQCG-SGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSS--S 238
             ++  H S+G      S S  + + G+  +     SS DT  + SG +S F +  ++  S
Sbjct: 391  ASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHS 450

Query: 239  GQSSGYSQHGSGSGHSSGYGQHGS-------------------RSGQSSRGERHRSSSGS 279
              SS  + H S S  + G+ +  +                    SG       +  S GS
Sbjct: 451  SPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGS 510

Query: 280  SSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGS-----GHSSSHGQHGSGSSYSYS 334
            + +   H   S  + GH  + +    S +H +  + S      H+S H   GS  +  + 
Sbjct: 511  TQT--MHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFR 568

Query: 335  RGHYESGSGQTSGFGQHESGSGQSSGYSKHGS--------------GSGHSSSQGQHGST 380
                 SG  + S    H S    ++     GS               SG   +    GST
Sbjct: 569  DSSTISGRSEESK-ASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGST 627

Query: 381  SGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPG--HGQRGSGSGQSPS 438
            +    S       S   S    H  AS  SSG  + S+ S   PG  H     GS   P 
Sbjct: 628  TKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG 687

Query: 439  SGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSR- 497
              Q  T    +S S P  + +  S G              T    G  +++ H + GS  
Sbjct: 688  LSQEST----ASHSSPGPTDTTLSPG------------STTASSLGPEYTTFHSRPGSTE 731

Query: 498  -----SGQSSRGERQGSSAGSSSSYGQH------GSGSRQSLGHSRHGSGSGQSPSPSRG 546
                    ++ G  + S    SS+   H      GS +RQ    + H   S +   P+  
Sbjct: 732  TTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPP 791

Query: 547  RHESG-------SRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQES----RSGQSS 595
               S        S  S S  P  + S RS++ G  E  + + S  G  ++     S  +S
Sbjct: 792  TTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTS 851

Query: 596  GYGQHGSSSGHSSTHGQHGSTSGQS----------SSCGQHGATSGQSSSHGQHGSGSSQ 645
            G G+  ++S  S+TH    + S  S          SS G    T    SS     S  S 
Sbjct: 852  GRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEEST 911

Query: 646  SSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKS 705
            +S   Q  +G+   P+R       G S++       SG   +    GS +  + G   +S
Sbjct: 912  ASHSSQDATGTIVLPARSTTSVLLGESTT---SPISSGSMETTALPGSTT--TPGLSERS 966

Query: 706  GSGQSSGYSQH---GSGSSHSSGYRKHG--SRSGQSSRSEQHGSSSGLSSSYGQHGSGSH 760
             +  SS  S        S+ SSG  +    SRS   S        S  +    +H + SH
Sbjct: 967  TTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSH 1026

Query: 761  QSSGH------GRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCS----SSCGHYESG 810
             S G           + SG S       SSSG + +    GS T+ S    S+  H   G
Sbjct: 1027 SSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPG 1086

Query: 811  SGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQH 870
            S   + F    + SG       S   H S+     + S  SS+S       G+S+++  H
Sbjct: 1087 STHTTLFPDSTTSSG---IVEASTRVHSSTGSPRTTLSPASSTS---PGLQGESTAFQTH 1140

Query: 871  ESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGS---GSG 927
             +++H         +   +      R  GS  +  +    + SG S  S    S    SG
Sbjct: 1141 PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASG 1200

Query: 928  QSSGFGHKSSSGQSSGYTQHGS-GSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQH 986
             +    H ++SG+    T   S GS   ++     +  G S  S    SS  S ++    
Sbjct: 1201 TTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT--TL 1258

Query: 987  GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESG-SG 1045
               S  SLG G+  + S   P  +       S  +       S + +SSSRG  E+    
Sbjct: 1259 SPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSE-ESTTVYSSSRGSTETTVFP 1317

Query: 1046 HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQH 1105
            HS+      S  G+         +S H++   +  +TSG +    +  A  G  +S    
Sbjct: 1318 HST----TTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTE---ESTAFPGSPASTQTG 1370

Query: 1106 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHG----SGL 1161
               +  ++  G + +    S G     +G++ SP+         RS++SG  G    S L
Sbjct: 1371 LPATLTTADLGEESTTFPSSSG----STGTKLSPA---------RSTTSGLVGESTPSRL 1417

Query: 1162 GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQ 1221
              SS        S  + S S+  S + ++S      + S  ++     G S  SS+ + Q
Sbjct: 1418 SPSSTETTTLPGSPTTPSLSEK-STTFYTSPRSPDATLSPATTTSS--GVSEESSTSHSQ 1474

Query: 1222 HGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHS 1281
             GS    +       S     P+      G    S+      GS  +SS G  +S + HS
Sbjct: 1475 PGSTHTTAFPDSTTTSDLSQEPTTSHSSQG----STEATLSPGSTTASSLG-QQSTTFHS 1529

Query: 1282 SVFGQHE----------SGSGHSSAYSQHGSGSGHFCSQGQHGSTSG---QSSTFDQEGS 1328
            S  G  E          SG   +S  +   +GS H        +++G   +S+TF    S
Sbjct: 1530 SP-GDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPS 1588

Query: 1329 STGQS-SSYGHRGSGSSQSSGYGRHGAG------SGQSPSRGRHGSGSGHSSSYGQHGSG 1381
            S+  + S  G   +    S+ Y    +       S  S + GR    +   SS G  G+ 
Sbjct: 1589 SSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTA 1648

Query: 1382 --SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSR 1439
                 S++S   G  +      G  E+++   S  T   +G    S+      RS  ++ 
Sbjct: 1649 LFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT---AGLSEKSTTFYSSPRSPDTTL 1705

Query: 1440 GERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGS 1499
                 +SSG S       S SR    H     GS   P  S+    S S   S+ +    
Sbjct: 1706 SPASTTSSGVSEE--STTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSP 1763

Query: 1500 GSGWSSSRGPYESGSSHSSGLGHRESR----SGQSSGYGQHGSSSGHSSTHGQHGSTSGQ 1555
            GS  +SS GP ES + HSS  G  E+     +  +SG     S+  HSST   H + S  
Sbjct: 1764 GSTTASSLGP-ESTTFHSSP-GSTETTLLPDNTTASGL-LEASTPVHSSTGSPHTTLSPA 1820

Query: 1556 SSSCGQHGASSGQS--SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 1613
             S+  Q  +++ QS  SS     +  + +S +    + S  SP        S  S + GR
Sbjct: 1821 GSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGR 1880

Query: 1614 -------HGSGSGRS---SSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGY 1663
                   H S    +   S +    SGL E S   H    S Q+  + +  + SG S   
Sbjct: 1881 SEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRS--- 1937

Query: 1664 GQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGR-HGSGL 1722
                SR+  SS      S   ++S   +  +    S G          S + GR   S  
Sbjct: 1938 --EESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTA 1995

Query: 1723 GHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSG------H 1776
             HSS   Q  +G+    +R       G S+      SGS  ++A     +  G       
Sbjct: 1996 SHSS---QDATGTIVLPARSTTSVLLGESTT-SPISSGSMETTALPGSTTTPGLSEKSTT 2051

Query: 1777 FCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGS-------------GSSQSSSYGQQG 1823
            F S  +  +T+   ++    G S   ++SH + GS             G S+ S+     
Sbjct: 2052 FHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 2111

Query: 1824 SGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 1883
             GS  +       + SG S       S  G + ++   GS +  S G    ES+++ SS 
Sbjct: 2112 PGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFG---QESTTFHSS- 2167

Query: 1884 YTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1943
                  GS H++ +    + SG      +  SS+GS  +     S    S   G  G  +
Sbjct: 2168 -----PGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPAS----STSPGLQGEST 2218

Query: 1944 GQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRG--PYESGSGHSSGLGHRESRSGQSS 2001
                 P+   H + S  S++  P    + +  S G  P       S+  GH E  +   S
Sbjct: 2219 AFQTHPA-STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHS 2277

Query: 2002 GYGQHGS--SSGHSSTHGQHGSASGQSS-----------SCGQHGASSGQSSSHGQHGS- 2047
                 G+  SS HS+T G+  S + + S           S    G S   ++ +    S 
Sbjct: 2278 SPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSP 2337

Query: 2048 ------GSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGL 2101
                   S  S G G + + S   PG     + S  SP+       S  S++     PG 
Sbjct: 2338 TTTLSPASMTSLGVGEESTTSRSQPG----STHSTVSPASTTTPGLSEESTTVYSSSPGS 2393

Query: 2102 GESSGFGHHESSS--GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRY 2159
             E++ F    ++S  G+  +       S H++ + +  + SG +        S  S+   
Sbjct: 2394 TETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQ-- 2451

Query: 2160 GQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSG 2219
                +G   +      G  S   PS     SGS  ++      + SG      P  SR  
Sbjct: 2452 ----TGLPATLTTADLGEESTTFPS----SSGSTGTTLSPARSTTSGLVGESTP--SRLS 2501

Query: 2220 HSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQH 2279
             SS       GS  + + S+    S  F +  +    +   +T    G S   S+SH Q 
Sbjct: 2502 PSSTETTTLPGSPTTPSLSEK---STTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQP 2558

Query: 2280 GS-------------GSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS 2326
            GS             G S+ S+      GS  +       + SG S       S  G + 
Sbjct: 2559 GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTD 2618

Query: 2327 SSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSS 2386
            ++   GS +  S G    ES+++ SS       GS H++ +    + SG      R  SS
Sbjct: 2619 TALSPGSTTALSFG---QESTTFHSS------PGSTHTTLFPDSTTSSGIVEASTRVHSS 2669

Query: 2387 SGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSS 2446
            +GS  +     S    S   G  G  +     P+   H + S  S++ +P    + +  S
Sbjct: 2670 TGSPRTTLSPAS----STSPGLQGESTTFQTHPA-STHTTPSPPSTATAPVEESTTYHRS 2724

Query: 2447 RG--PYESGSGHSSGLGHRESRSGQSSGYGQHGS--SSGHSSTHGQHGSTSGQSS----- 2497
             G  P       S+  GH E  +   S     G+  SS HS+T G+  ST+ + S     
Sbjct: 2725 PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE 2784

Query: 2498 ------SCGQHGASSGQSSSHGQHGS-------GSSQSSGYGRQGSGSGQSPGHGQRGSG 2544
                  S    G S   ++ +    S        S  S G G + + S   PG     + 
Sbjct: 2785 ITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG----STH 2840

Query: 2545 SRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS--GQSSSYSQHGSGSGHSSG 2602
            S  SP+       S  S++      G  E++ F    ++S  G+  +       S H++ 
Sbjct: 2841 STVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTL 2900

Query: 2603 YGQHGSRSGQSSRGERHGSSSGS----------SSHYGQHGSGSRQSSGHGRQGSGSGQS 2652
            + +  + SG +        S  S          ++  G+  +    SSG     +G+  S
Sbjct: 2901 FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSG----STGTTLS 2956

Query: 2653 PSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGS 2712
            P+R      +G S+                   SRL  SS       GS  + + S+   
Sbjct: 2957 PARSTTSGLVGEST------------------PSRLSPSSTETTTLPGSPTTPSLSE--K 2996

Query: 2713 GSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQS--- 2769
             +  + S     +T   ++T     S   + SS  H   GS+ ++ +      SG S   
Sbjct: 2997 STTFYTSPRSPDATLSPATT---TSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEP 3053

Query: 2770 -LSHGRHGS-------GSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDG 2821
              SH   GS       GS  +SS GQ  +    S G ++          S     S    
Sbjct: 3054 TASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTH 3113

Query: 2822 GSSGSYFLSFPSSTSPYEYVQEQRCYF 2848
             S+GS   +   ++S    +QE+   F
Sbjct: 3114 SSTGSLHTTLTPASSTSAGLQEESTTF 3140



 Score =  201 bits (511), Expect = 9e-51
 Identities = 650/2864 (22%), Positives = 1039/2864 (36%), Gaps = 419/2864 (14%)

Query: 198  GSGQSPNYGQHGSG--SGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSS 255
            GS  +P+  +  +   +   S + T    +  SSG S+  S+S     +SQ   GS H++
Sbjct: 1429 GSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTS-----HSQ--PGSTHTT 1481

Query: 256  GYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHG-- 313
             +    + S  S       SS GS+ +    GS +  SLG  +Q +    SP        
Sbjct: 1482 AFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLG--QQSTTFHSSPGDTETTLL 1539

Query: 314  ------SGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSG 367
                  SG   +S+     +GS ++       + +  TS   Q ES + QS         
Sbjct: 1540 PDDTITSGLVEASTPTHSSTGSLHTTL-----TPASSTSAGLQEESTTFQSWP------- 1587

Query: 368  SGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHG 427
            S   ++    G+T+     S  +   SR SS+   H SAS  + GR + S+    SPG  
Sbjct: 1588 SSSDTTPSPPGTTAAPVEVSTTY--HSRPSSTPTTHFSASSTTLGRSEESTTVHSSPG-- 1643

Query: 428  QRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGH 487
               +G+   P+        G  ++S P  SGS  ++        S  ++G ++  S + +
Sbjct: 1644 --ATGTALFPTRSATSVLVGEPTTS-PISSGSTETTAL----PGSTTTAGLSEK-STTFY 1695

Query: 488  SSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGS-------GSRQSLGHSRHGSGSGQS 540
            SS      + S  S+     G S  S++S+ + GS       GS    G S+  + S  S
Sbjct: 1696 SSPRSPDTTLSPASTTSS--GVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSS 1753

Query: 541  PSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQH 600
            P  +      GS  +SS GP        S+      GS  ++ L    + SG        
Sbjct: 1754 PGSTDTTLSPGSTTASSLGPE-------STTFHSSPGSTETTLLPDNTTASGLLEA---- 1802

Query: 601  GSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQS--SSHGQHGSGSSQSSRYGQQGSGSGQ 658
             S+  HSST   H + S   S+  Q  +T+ QS  SS     +  + +S + +  + S  
Sbjct: 1803 -STPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHG 1861

Query: 659  SPSRGRHGSDFGHSSSYGQ-------HGSGSGWSSSNGPHGSVSG----QSSGFGHKSGS 707
            SPS          S++ G+       H S    +++  P  S +     +S+ +    GS
Sbjct: 1862 SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGS 1921

Query: 708  GQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGR 767
             Q+     H   SS +SG R   SR+  SS +    S    +S+  +  +  H S G   
Sbjct: 1922 TQT----MHFPESSTASG-RSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPG--- 1973

Query: 768  QGSGSGHSP-SRVRHGSSSGHSSSHG-QHGSGTSCSSSCGHYESGSGQASGFGQHESGSG 825
              + + H P S    G S   ++SH  Q  +GT    +        G+++      SGS 
Sbjct: 1974 -STATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT-SPISSGSM 2031

Query: 826  QGYSQHGSA--------SGHFSSQGRHGSTS---GQSSSSGQHDSSSGQSSSYGQ-HESA 873
            +  +  GS         S  F S  R  +T+     ++SSG  + S+   S  G  H +A
Sbjct: 2032 ETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTA 2091

Query: 874  ---SHHASGRGRHGSGSGQSPGHGQR----GSGSGQSPSYGRHGSGSGRSSSSGRHGSGS 926
               S    G  RH + S  SPG         S +   PS     S S   S+      GS
Sbjct: 2092 FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGS 2151

Query: 927  GQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQH 986
              +  FG +S++  SS       GS H++ +    + SG    S +  SS+GS  +    
Sbjct: 2152 TTALSFGQESTTFHSS------PGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSP 2205

Query: 987  GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRG--PYESGS 1044
             S    S   G  G  +     P+   H + S  S++  P    + +  S G  P     
Sbjct: 2206 AS----STSPGLQGESTAFQTHPA-STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFP 2260

Query: 1045 GHSSGLGHRESRSGQSSGYGQHGS--SSGHSSTHGQHGSTSGQSS-----------SCGQ 1091
              S+  GH E  +   S     G+  SS HS+T G+  ST+ + S           S   
Sbjct: 2261 ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTT 2320

Query: 1092 HGASSGQSSSHGQHGS-------GSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 1144
             G S   ++ +    S        S  S G G + + S   PG     + S  SP+    
Sbjct: 2321 PGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG----STHSTVSPASTTT 2376

Query: 1145 GSGSGRSSSSGQHGSGLGESSGFGHHESSS--GQSSSYSQHGSGSGHSSGYGQHGSRSGQ 1202
               S  S++      G  E++ F    ++S  G+  +       S H++ + +  + SG 
Sbjct: 2377 PGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGL 2436

Query: 1203 SSRGERHGSSSGSS----------SHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGL 1252
            +        S  S+          +  G+  +    SSG     +G+  SP+R      +
Sbjct: 2437 TEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSG----STGTTLSPARSTTSGLV 2492

Query: 1253 GHSSSHGQHGSGSGRSSSRGP--YESRSGHSSVFGQH--------------ESGSGHSSA 1296
            G S+      S +  ++  G     S S  S+ F                  SG    S+
Sbjct: 2493 GESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESS 2552

Query: 1297 YSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSY----GHRGSGSSQSSGYGRH 1352
             S    GS H  +     +T G S       SS G + +         SG SQ S     
Sbjct: 2553 TSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHS 2612

Query: 1353 GAGS---------------GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQ 1397
              GS               GQ  +      GS H++ +    + SG   +S R  S +G 
Sbjct: 2613 SPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS 2672

Query: 1398 -----------SSGFGHHESSSWQSSGCTQHGSGSGHSSSY----EQHGSRSGQSSRGER 1442
                       S G    ES+++Q+   + H + S  S++     E         S    
Sbjct: 2673 PRTTLSPASSTSPGL-QGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT 2731

Query: 1443 HGSSSGSSSSYGQHG---------SGSRQSLGHGQHGSGSGQSPSPSRGRHGS------- 1486
            H  +S ++S + +           SG+  S  H    SG G+S + SR   GS       
Sbjct: 2732 HFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTT-SGRGESTT-SRISPGSTEITTLP 2789

Query: 1487 GSGQSSSYSPYGSGSGWSSSRGPYES---GSSHSSGLGHRESRSGQSSGYGQHGSSSGHS 1543
            GS  +   S   S + +SS R P  +    S  S G+G   + S    G      S   +
Sbjct: 2790 GSTTTPGLSE-ASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAST 2848

Query: 1544 STHG-QHGSTSGQSSSCGQHGAS-------------------SGQSSSHGQHGSGSSQSS 1583
            +T G    ST+  SSS G    +                   S  +S+H    +  S +S
Sbjct: 2849 TTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTS 2908

Query: 1584 GYGRQGSGSGQSPGHGQRGSGS--------RQSPSYGRHGSGSG------RSSSSGQHG- 1628
            G   + +    SP   Q G  +         +S ++      +G      RS++SG  G 
Sbjct: 2909 GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGE 2968

Query: 1629 ---SGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRS 1685
               S L  SS        S  + S S+  S + ++S      + S  ++     G S  S
Sbjct: 2969 STPSRLSPSSTETTTLPGSPTTPSLSEK-STTFYTSPRSPDATLSPATTTSS--GVSEES 3025

Query: 1686 SSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYE 1745
            S+ + Q GS    +       SG  Q P+      G    S+      GS  +SS G  +
Sbjct: 3026 STSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQG----STEATLSPGSTTASSLGQ-Q 3080

Query: 1746 SRSGHSSVFGQHE----------SGSGHSSAYSQHGSGSGHFCSQGQHGSTSG---QSST 1792
            S + HSS  G  E          SG   +S  +   +GS H        +++G   +S+T
Sbjct: 3081 STTFHSSP-GDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTT 3139

Query: 1793 FDQEGSSTGQSSSH-GQHGSGSSQSSSYGQQGSG------SGQSPSRGRHGSGSGHSSSY 1845
            F    SS+  + S  G   +    S++Y  + S       S  S + GR    +   SS 
Sbjct: 3140 FQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP 3199

Query: 1846 GQHGSG--SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSR 1903
            G  G+      S++S   G  +      G  E+++   S  T   +G    S+      R
Sbjct: 3200 GATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT---AGLSEKSTTFYSSPR 3256

Query: 1904 SGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSS 1963
            S  ++      +SSG S       S SR    H     GS   P  S+    S S   S+
Sbjct: 3257 SPDTTLSPASTTSSGVSEE--STTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGST 3314

Query: 1964 YGPYGSGSGWSSSRGPYESGSGHSSGLGHRESR----SGQSSGYGQHGSSSGHSSTHGQH 2019
                  GS  +SS GP ES + HS G G  E+     +  +SG  +  S+  HSST   H
Sbjct: 3315 DTTLSPGSTTASSLGP-ESTTFHS-GPGSTETTLLPDNTTASGLLE-ASTPVHSSTGSPH 3371

Query: 2020 GSASGQSSSCGQHGASSGQS--SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ 2077
             + S   S+  Q  +++ QS  +S     +  + +S +    + S  SP        S  
Sbjct: 3372 TTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS 3431

Query: 2078 SPSYGRHGSGSGRSSS----SGQHGPGLGESSGFGHHESS--SGQSSSYSQHGSGSGHSS 2131
            S + GR    +   SS    +    P    +SG     ++  S   S+ + H   S  +S
Sbjct: 3432 STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTS 3491

Query: 2132 GYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSG 2191
            G G+  + S  SS      S+  ++S   +  +    S G          S + GR    
Sbjct: 3492 GRGEESTTS-HSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES 3550

Query: 2192 SGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQG 2251
            +   SS  Q  +G+    +R       G S+      SGS  ++A     +  G      
Sbjct: 3551 TASHSS--QDATGTIVLPARSTTSVLLGESTT-SPISSGSMETTALPGSTTTPGLSEKST 3607

Query: 2252 QHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGH 2311
               S+    +T     S+T    S     S S   S++      S  +P   RH + S H
Sbjct: 3608 TFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTS-H 3666

Query: 2312 SSSYGQHG---------SGSGWSSSSGRHGSGSGQSS-GFGHHESSSWQSSGYTQHGS-G 2360
            SS               SGS   S++    SGS  ++   G   + S+     T H S G
Sbjct: 3667 SSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPG 3726

Query: 2361 SGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPS 2420
            S H++ +    + SG      R  SS+GS  +     S    S   G  G  +     P+
Sbjct: 3727 STHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPAS----STSPGLQGESTAFQTHPA 3782

Query: 2421 RGRHGSGSGQSSSYSPYGSGSGWSSSRG--PYESGSGHSSGLGHRESRSGQSSGYGQHGS 2478
               H + S  S++ +P    + +  S G  P       S+  GH E  +   S     G+
Sbjct: 3783 -STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGT 3841

Query: 2479 --SSGHSSTHGQHGSTSGQSS-----------SCGQHGASSGQSSSHGQHGS-------G 2518
              SS HS+T G+  ST+ + S           S    G S   ++ +    S        
Sbjct: 3842 TPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPA 3901

Query: 2519 SSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFG 2578
            S  S G G + + S   PG     + S  SP+       S  S++      G  E++ F 
Sbjct: 3902 SMTSLGVGEESTTSRSQPG----STHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFP 3957

Query: 2579 HHESSSGQSSSYSQHGS--GSGHSSGYGQHGSRSGQSSRGERHGSSSGSS---------- 2626
               ++S +    +   S   S H++ + +  + SG +        S  S+          
Sbjct: 3958 RSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTT 4017

Query: 2627 SHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRS-------- 2678
            +  G+  +    SSG     +G+  SP+R      +G S+      S +  +        
Sbjct: 4018 ADLGEESTTFPSSSG----STGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTT 4073

Query: 2679 ------------SSRGP---------YESRLGHSSVFGQHESGSGHSSAYSQHGSGSG-- 2715
                        S R P           S +   S     + GS H++A+    + SG  
Sbjct: 4074 PSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLS 4133

Query: 2716 --HFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSS 2757
                 S    GST    S      SS GQ S+  H   G ++++
Sbjct: 4134 QEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETT 4177



 Score =  196 bits (498), Expect = 3e-49
 Identities = 633/2830 (22%), Positives = 988/2830 (34%), Gaps = 416/2830 (14%)

Query: 203  PNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQ--HGSGSGHSSGYGQH 260
            P+   HGS    SS   TH S    +SG  +  ++   S G +Q  H   S  +SG G+ 
Sbjct: 800  PSTTSHGS---PSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 856

Query: 261  GSRSGQSSRGERHRSSSGSSSSYG-------QHGSGSRQSLGHGRQGS--GSRQSPSHVR 311
             + S  S+    H  SS  S++          H S    +  H    S    R   S   
Sbjct: 857  STTSHSSTT---HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTAS 913

Query: 312  HGSGSGHSSSHGQHGSGSSY---SYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGS 368
            H S     +      S +S      +     SGS +T+      +  G S   +   S  
Sbjct: 914  HSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSP 973

Query: 369  GHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQ 428
               ++     ST+    S     S SR  S++      S  + G  +HS+ S  SPG   
Sbjct: 974  RSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTD 1033

Query: 429  RGSGSGQSPSSGQHGTGFGRSSSSG----PYVSGSGYSSGFGHHESSSEHSSGYTQHGS- 483
                   + +SG         SSSG        GS  +  FG  ES++ HS+  + H + 
Sbjct: 1034 TTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFG-QESTTFHSNPGSTHTTL 1092

Query: 484  --GSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSP 541
               S  SSG  +  +R   S+   R   S  SS+S G  G    +S     H + +  +P
Sbjct: 1093 FPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQG----ESTAFQTHPASTHTTP 1148

Query: 542  SPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHG 601
            SP      +   +S++Y        RS    P       S+  GH E  +   S     G
Sbjct: 1149 SPP-STATAPVEESTTY-------HRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASG 1200

Query: 602  S--SSGHSSTHGQHGSTSGQSS-----------SCGQHGATSGQSSSHGQHGSGSSQSSR 648
            +  SS HS+T G+  ST+ + S           S    G +   ++ +    S ++  S 
Sbjct: 1201 TTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSP 1260

Query: 649  YGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSG--------WSSSNG-------PHG- 692
                  G G+  +  R      HS+      +  G        +SSS G       PH  
Sbjct: 1261 ASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHST 1320

Query: 693  --SVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSS 750
              SV G+     H   S  +S ++   +  S +SG  +  +    S  S Q G  + L++
Sbjct: 1321 TTSVHGEEPTTFH---SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTT 1377

Query: 751  S-YGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCG---- 805
            +  G+  +    SSG     +G+  SP+R       G S+      S T  ++  G    
Sbjct: 1378 ADLGEESTTFPSSSG----STGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTT 1433

Query: 806  ------------HYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSS 853
                           S     S      SG  +  S   S  G   +     ST+    S
Sbjct: 1434 PSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLS 1493

Query: 854  SGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGS 913
                 S S Q S+       S  AS  G+  +    SPG  +       + + G   + +
Sbjct: 1494 QEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEAST 1553

Query: 914  GRSSSSGRHGS----GSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 969
               SS+G   +     S  S+G   +S++ QS             SS +   S  G ++ 
Sbjct: 1554 PTHSSTGSLHTTLTPASSTSAGLQEESTTFQS-----------WPSSSDTTPSPPGTTAA 1602

Query: 970  SEQHGSS--SGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPY 1027
              +  ++  S  SS+   H S S  +LG  +           S   H S     ++  P 
Sbjct: 1603 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEE----------STTVHSSPGATGTALFPT 1652

Query: 1028 RSGSG---WSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSG 1084
            RS +       +  P  SGS  ++ L    + +G S       S++ +SS      + S 
Sbjct: 1653 RSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLS-----EKSTTFYSSPRSPDTTLSP 1707

Query: 1085 QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 1144
             S++    G S   ++SH + GS  + +        GS   PG  Q  + S  SP     
Sbjct: 1708 ASTT--SSGVSEESTTSHSRPGSTHTTAF------PGSTTMPGVSQESTASHSSP----- 1754

Query: 1145 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 1204
            GS     S      S LG  S   H    S +++    + + SG         S    SS
Sbjct: 1755 GSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGL-----LEASTPVHSS 1809

Query: 1205 RGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSG 1264
             G  H + S +       GS +RQ    G   +      S+    +    +S+  +  + 
Sbjct: 1810 TGSPHTTLSPA-------GSTTRQ----GESTTFQSWPSSKDTMPAPPTTTSAFVELSTT 1858

Query: 1265 SGRSSSRGPYESRSGHSSVFGQ-HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF 1323
            S  S S  P    S  S+  G+  ES + HSS                   +T+   S  
Sbjct: 1859 SHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPV-----------------ATATTPSPA 1901

Query: 1324 DQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQS-PSRGRHGSGSGHSSSYGQHGSGS 1382
                S   + S+  H   GS+Q+  +      SG+S  SR  H S +   SS     S  
Sbjct: 1902 RSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSAL 1961

Query: 1383 GWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGER 1442
                +S     GS  ++ F    ++S +S   T   S    + +       +     GE 
Sbjct: 1962 VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES 2021

Query: 1443 HGS--SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSG 1500
              S  SSGS  +    GS +   L               S   H S    +++ SP  + 
Sbjct: 2022 TTSPISSGSMETTALPGSTTTPGLS------------EKSTTFHSSPRSPATTLSPASTT 2069

Query: 1501 SGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSG---HSST-HGQHGSTSGQ- 1555
            S          SG S  S   H    S  ++ +    ++ G   HS+T H   GST    
Sbjct: 2070 S----------SGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL 2119

Query: 1556 -SSSCGQHGASSGQSSSHGQHGS-------GSSQSSGYGRQGSGSGQSPG--------HG 1599
              +S    G S   ++SH   GS       GS+ +  +G++ +    SPG          
Sbjct: 2120 LPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS 2179

Query: 1600 QRGSGSRQSPSYGRHGSGSGRS--SSSGQHGSGL-GESSGFGHHESSSG----------- 1645
               SG  ++ +     +GS R+  S +     GL GES+ F  H +S+            
Sbjct: 2180 TTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATA 2239

Query: 1646 --QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHG 1703
              + S+      GS  ++ +    + SG S +     SS           SG+  SS H 
Sbjct: 2240 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSS--------PDASGTTPSSAHS 2291

Query: 1704 RQGSGSGQSPSRGRHGSG-----LGHSSSHG-QHGSGSGRSSSRGPYESRSGHSSVFGQH 1757
                    + SR   GS       G +++ G    S +  SS R P  + S  S      
Sbjct: 2292 TTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMT---- 2347

Query: 1758 ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSS 1817
              G G  S  S+   GS H        +T G S     E S+T  SSS      GS++++
Sbjct: 2348 SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLS-----EESTTVYSSS-----PGSTETT 2397

Query: 1818 SYGQQGSGS--GQSPSRGRHGSGSGHSSSYGQHGSGSGWS-SSSGRHGSGSGQSSGFGHH 1874
             + +  + S  G+ P+       S H++ + +  + SG +  S+   GS +   +G    
Sbjct: 2398 VFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPAT 2457

Query: 1875 ESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSL 1934
             +++      T   S SG + +       +     GE   S    SS+      GS  + 
Sbjct: 2458 LTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTP 2517

Query: 1935 GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRE 1994
               +  +    SP        S     S      SG    SS    + GS H++      
Sbjct: 2518 SLSEKSTTFYTSPR-------SPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAF---- 2566

Query: 1995 SRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGS------- 2047
              S  + G  +H S++ HSS      +    S++    G S   ++SH   GS       
Sbjct: 2567 PDSTTTPGLSRH-STTSHSSPGSTDTTLLPASTTTS--GPSQESTTSHSSPGSTDTALSP 2623

Query: 2048 GSSQSSGYGRQGSGSGQSPG--------HGQRGSGSRQSPSYGRHGSGSGRS--SSSGQH 2097
            GS+ +  +G++ +    SPG             SG  ++ +     +GS R+  S +   
Sbjct: 2624 GSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASST 2683

Query: 2098 GPGL-GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSS 2156
             PGL GES+ F  H +S+  + S     +     S        S  ++      ++SG S
Sbjct: 2684 SPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHS 2743

Query: 2157 SR-----YGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGS-----GHSSSHG-QHGSGS 2205
             +          SG+  SS H         + SR   GS       G +++ G    S +
Sbjct: 2744 EKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTT 2803

Query: 2206 GRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 2265
              SS R P  + S  S        G G  S  S+   GS H        +T G S     
Sbjct: 2804 FYSSPRSPTTTLSPASMT----SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLS----- 2854

Query: 2266 EGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS--GQSPSRGRHGSGSGHSSSYGQHGSGSG 2323
            E S+T  SSS      GS++++ + +  + S  G+ P+       S H++ + +  + SG
Sbjct: 2855 EESTTVYSSS-----PGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSG 2909

Query: 2324 ----------------------------------WSSSSGRHGS----GSGQSSGFGHHE 2345
                                              + SSSG  G+        +SG     
Sbjct: 2910 LTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGES 2969

Query: 2346 SSSWQSSGYTQHGS--GSGHSSSYEQHGS------RSGQSSRGERHGSSSG----SSSSY 2393
            + S  S   T+  +  GS  + S  +  +      RS  ++      +SSG    SS+S+
Sbjct: 2970 TPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSH 3029

Query: 2394 GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESG 2453
             Q GS    +       SG  Q P+ S    GS     S  S   S  G  S+      G
Sbjct: 3030 SQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPG 3089

Query: 2454 SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHG 2513
               ++ L      SG         S+  HSST   H + +  SS+    G     ++   
Sbjct: 3090 DTETTLLPDDTITSGL-----VEASTPTHSSTGSLHTTLTPASSTSA--GLQEESTTFQS 3142

Query: 2514 QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSG------SRQSPSYGRHGSGSGRSSSSGQH 2567
               S  +  S  G   +    S  +  R S       S  S + GR    +   SS G  
Sbjct: 3143 WPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGAT 3202

Query: 2568 GSGL-----GESSGFGHHES---SSGQSSSYSQHGS----GSGHSSGYGQHGSRSGQSSR 2615
            G+ L       S   G   +   SSG + + +  GS    G    S       RS  ++ 
Sbjct: 3203 GTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTL 3262

Query: 2616 GERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGS 2675
                 +SSG S       S SR  S H     GS   P     G     ++SH   GS  
Sbjct: 3263 SPASTTSSGVSEE--STTSHSRPGSTHTTAFPGSTTMP-----GVSQESTASHSSPGSTD 3315

Query: 2676 GRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHF-CSQGQHGSTSGQSSTFD 2734
               S      S LG  S       GS  ++    + + SG    S   H ST    +T  
Sbjct: 3316 TTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLS 3375

Query: 2735 QEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSG-QSLSHGRHGSGSGQSSSYGQHGSGSG 2793
              GS+T Q  S   +   +S+ +        S    LS   HGS    SS+   H S S 
Sbjct: 3376 PAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGS---PSSTPTTHFSASS 3432

Query: 2794 QSSGYSQHGS 2803
             + G S+  +
Sbjct: 3433 TTLGRSEEST 3442



 Score =  190 bits (483), Expect = 2e-47
 Identities = 619/2707 (22%), Positives = 962/2707 (35%), Gaps = 390/2707 (14%)

Query: 385  SSSGQHGSSSRQSSSYGQHESASRHSSGRGQ---------HSSGSGQSPGHGQR------ 429
            +S G  G    +  S G   S    ++G  +         HS+ SG S   G        
Sbjct: 115  ASPGDDGDGRAEGFSLGLPLSEQARAAGAREKERQETVINHSTFSGFSQITGSTVNTSIG 174

Query: 430  -GSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHS 488
              + S  +PSS    T F     S  +++GS  +  F    ++S HS   T   SG G +
Sbjct: 175  GNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEESTVSHSGPG-A 233

Query: 489  SGHGQHGSRSGQS-SRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGR 547
            +G     S S  S   GE + S   S+S       GS  + G S   +    SP  S  R
Sbjct: 234  TGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPR-SPDR 292

Query: 548  HESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHS 607
              S +R +SS      G    S+      G  H+       +  G S       S  G +
Sbjct: 293  TLSPARTTSS------GVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGST 346

Query: 608  STHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGS 667
             T    G+T+   SS G    T   S  + +       ++  G   + +    S G   +
Sbjct: 347  DTTLSPGTTT--PSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHT 404

Query: 668  DFGHSSSYGQHGSGS---GWSSSNGPHGSVSGQSSGFGHKS---GSGQSSGYSQHGSGSS 721
                SSS    G  +    W SS     + SG +S F   S    S  SS  + H S SS
Sbjct: 405  TLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASS 464

Query: 722  HSSGYRKHGS-------RSGQSSRSEQHGSSSGLSSSYGQHGS-GSHQSSGHGRQGSGSG 773
             + G+ +  +        +  +    +  +S  +  S   H S GS Q+       + SG
Sbjct: 465  TTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSG 524

Query: 774  HSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGH--YESGSGQASGFGQHESGSGQGYSQH 831
            HS        S+ H+ S     S  S +++  H  Y S  G        +S +  G S+ 
Sbjct: 525  HSEESATFHGSTTHTKS-----STPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEE 579

Query: 832  GSASGHFSSQGRHGST---SGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSG 888
              AS   SS     +T   +G + S    DS+    SS     +A            GS 
Sbjct: 580  SKAS--HSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTAL----------PGST 627

Query: 889  QSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHG 948
              PG  ++ +    SP            S    H   S  SSG   +S++  S       
Sbjct: 628  TKPGLSEKSTTFYSSP-----------RSPDTTHLPASMTSSGVSEESTTSHSR------ 670

Query: 949  SGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLG------HGQHGSG 1002
             GS H++++    +  G S  S    SS G + +    GS +  SLG      H + GS 
Sbjct: 671  PGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGST 730

Query: 1003 S----GQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHS--SGLGHRESR 1056
                   + + S     S    SS+  P+ + S   S+    ES + HS  S    R + 
Sbjct: 731  ETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAP 790

Query: 1057 SGQSSGYGQ-----HGSSSGHSSTH-GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS 1110
               +S + +     HGS S   +TH     +TSG       + +S G  S+   H   S 
Sbjct: 791  PTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPG--STQTMHFPESD 848

Query: 1111 QSSGYGRQGSGSGQSPGHG------------------QRGSGSRQSPSYGRHGSGSGRS- 1151
             +SG G + + S  S  H                       GS  +  +    + SGRS 
Sbjct: 849  TTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSE 908

Query: 1152 ----SSSGQHGSG-------------LGESSGFGHHESSSGQSSSYSQHGS----GSGHS 1190
                S S Q  +G             LGES+       SSG   + +  GS    G    
Sbjct: 909  ESTASHSSQDATGTIVLPARSTTSVLLGEST---TSPISSGSMETTALPGSTTTPGLSER 965

Query: 1191 SGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGS 1250
            S       RS  ++      +SSG S       S SR  S H      S  +P   RH  
Sbjct: 966  STTFHSSPRSPATTLSPASTTSSGVSEE--STTSRSRPGSTHTTAFPDSTTTPGLSRHS- 1022

Query: 1251 GLGHSSSHGQHGSGS-----GRSSSRGP-YESRSGHSSVFGQHESGSGHSSAYSQHGSGS 1304
                ++SH   GS         +++ GP  ES + HSS      + S  S+     G  S
Sbjct: 1023 ----TTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQES 1078

Query: 1305 GHFCSQGQHGSTSGQSSTFDQEGSSTG--QSSSYGHRGSGSSQSSGYGRHGAGSGQSPSR 1362
              F S    GST   ++ F    +S+G  ++S+  H  +GS +++           SP+ 
Sbjct: 1079 TTFHS--NPGST--HTTLFPDSTTSSGIVEASTRVHSSTGSPRTT----------LSPAS 1124

Query: 1363 GRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSG 1422
                   G S+++  H + +  + S     +   + S   H    S  ++      + SG
Sbjct: 1125 STSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSG 1184

Query: 1423 HSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP--- 1479
            HS   +     S   + G    S+  ++S  G+  + SR S G  +  +  G + +P   
Sbjct: 1185 HSE--KSTIFHSSPDASGTTPSSAHSTTSGRGE-STTSRISPGSTEITTLPGSTTTPGLS 1241

Query: 1480 --SRGRHGSGSGQSSSYSPYGS---GSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYG 1534
              S   + S    +++ SP      G G  S+    + GS+HS+      +  G S    
Sbjct: 1242 EASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLS---- 1297

Query: 1535 QHGSSSGHSSTHGQHGST-SGQSSSCGQHGAS-----SGQSSSHGQHGSGSSQSSGYGRQ 1588
               S++ +SS+ G   +T    S++   HG       S  +S+H    +  S +SG   +
Sbjct: 1298 -EESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEE 1356

Query: 1589 GSGSGQSPGHGQRG---------SGSRQSPSYGRHGSGSGRSSSSGQHGSGL-GESSGFG 1638
             +    SP   Q G          G   +      GS   + S +    SGL GES+   
Sbjct: 1357 STAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGEST--- 1413

Query: 1639 HHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG----------ERHGSSSRSSSR 1688
               S    SS+ +    GS  +    +  +    S R              G S  SS+ 
Sbjct: 1414 --PSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTS 1471

Query: 1689 YGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRS 1748
            + Q GS    +       S   Q P+      G    S+      GS  +SS G  +S +
Sbjct: 1472 HSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQG----STEATLSPGSTTASSLG-QQSTT 1526

Query: 1749 GHSSVFGQHE----------SGSGHSSAYSQHGSGSGHFCSQGQHGSTSG---QSSTFDQ 1795
             HSS  G  E          SG   +S  +   +GS H        +++G   +S+TF  
Sbjct: 1527 FHSSP-GDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQS 1585

Query: 1796 EGSSTGQS-SSHGQHGSGSSQSSSYGQQGSG------SGQSPSRGRHGSGSGHSSSYGQH 1848
              SS+  + S  G   +    S++Y  + S       S  S + GR    +   SS G  
Sbjct: 1586 WPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGAT 1645

Query: 1849 GSG--SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQ 1906
            G+      S++S   G  +      G  E+++   S  T   +G    S+      RS  
Sbjct: 1646 GTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT---AGLSEKSTTFYSSPRSPD 1702

Query: 1907 SSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGP 1966
            ++      +SSG S       S SR    H     GS   P  S+    S S   S+   
Sbjct: 1703 TTLSPASTTSSGVSEE--STTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTT 1760

Query: 1967 YGSGSGWSSSRGPYESGSGHSSGLGHRESR----SGQSSGYGQHGSSSGHSSTHGQHGSA 2022
               GS  +SS GP ES + HSS  G  E+     +  +SG     S+  HSST   H + 
Sbjct: 1761 LSPGSTTASSLGP-ESTTFHSSP-GSTETTLLPDNTTASGL-LEASTPVHSSTGSPHTTL 1817

Query: 2023 SGQSSSCGQHGASSGQS--------------------SSHGQHGSGSSQSSGYGRQGSGS 2062
            S   S+  Q  +++ QS                     S   HGS SS  + +    S S
Sbjct: 1818 SPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTH---FSAS 1874

Query: 2063 GQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQ 2122
              + G  +  +    SP          RS++S     GL E S   H    S Q+  + +
Sbjct: 1875 STTLGRSEESTTVHSSPVATATTPSPARSTTS-----GLVEESTAYHSSPGSTQTMHFPE 1929

Query: 2123 HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHS 2182
              + SG S       SR+  SS      S   ++S   +  +    S G          S
Sbjct: 1930 SSTASGRS-----EESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSS 1984

Query: 2183 PSRGR-HGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHG 2241
             + GR   S + HSS   Q  +G+    +R       G S+      SGS  ++A     
Sbjct: 1985 TTSGRSEESTASHSS---QDATGTIVLPARSTTSVLLGESTT-SPISSGSMETTALPGST 2040

Query: 2242 SGSG------HFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGS-------------G 2282
            +  G       F S  +  +T+   ++    G S   ++SH + GS             G
Sbjct: 2041 TTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPG 2100

Query: 2283 SSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFG 2342
             S+ S+      GS  +       + SG S       S  G + ++   GS +  S G  
Sbjct: 2101 LSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFG-- 2158

Query: 2343 HHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQ 2402
              ES+++ SS       GS H++ +    + SG      R  SS+GS  +     S    
Sbjct: 2159 -QESTTFHSS------PGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPAS---- 2207

Query: 2403 SLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRG--PYESGSGHSSGL 2460
            S   G  G  +     P+   H + S  S++ +P    + +  S G  P       S+  
Sbjct: 2208 STSPGLQGESTAFQTHPA-STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTS 2266

Query: 2461 GHRESRSGQSSGYGQHGS--SSGHSSTHGQHGSTSGQSS-----------SCGQHGASSG 2507
            GH E  +   S     G+  SS HS+T G+  ST+ + S           S    G S  
Sbjct: 2267 GHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEA 2326

Query: 2508 QSSSHGQHGS-------GSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGR 2560
             ++ +    S        S  S G G + + S   PG     + S  SP+       S  
Sbjct: 2327 STTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG----STHSTVSPASTTTPGLSEE 2382

Query: 2561 SSSSGQHGSGLGESSGFGHHESSS--GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 2618
            S++      G  E++ F    ++S  G+  +       S H++ + +  + SG +     
Sbjct: 2383 STTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTA 2442

Query: 2619 HGSSSGS----------SSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSH 2668
               S  S          ++  G+  +    SSG     +G+  SP+R      +G S+  
Sbjct: 2443 FPGSPASTQTGLPATLTTADLGEESTTFPSSSG----STGTTLSPARSTTSGLVGESTPS 2498

Query: 2669 GQHGSGSGRSSSRG-PYESRLGHSSV--FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGS 2725
                S +  ++  G P    L   S   +    S     S  +   SG     S      
Sbjct: 2499 RLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQP 2558

Query: 2726 TSGQSSTFDQEGSSTGQS--SSYGHRGSGSSQSSGYGRHGAGSGQS----LSHGRHGS-- 2777
             S  ++ F    ++ G S  S+  H   GS+ ++        SG S     SH   GS  
Sbjct: 2559 GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTD 2618

Query: 2778 -----GSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGS--YFLS 2830
                 GS  + S+GQ  +    S G +           S     S     S+GS    LS
Sbjct: 2619 TALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS 2678

Query: 2831 FPSSTSP 2837
              SSTSP
Sbjct: 2679 PASSTSP 2685



 Score =  181 bits (460), Expect = 7e-45
 Identities = 643/2859 (22%), Positives = 992/2859 (34%), Gaps = 392/2859 (13%)

Query: 173  SGQSSSYGEQNSDSHQSSGRGQCGS--GSGQSPNYGQHGSGSGQS--SSNDTHGSGSGQS 228
            S  SS   E+++ SH   G     +   S  +P   +H + S  S  S++ T    S  +
Sbjct: 2067 STTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT 2126

Query: 229  SGFSQHKSSSGQSSGYSQHGSGSGHSSG--YGQHGSRSGQSSRGERHRS-------SSG- 278
            SG SQ  ++S  S G +      G ++   +GQ  S +  SS G  H +       SSG 
Sbjct: 2127 SGPSQESTTSHSSPGSTDTALSPGSTTALSFGQE-STTFHSSPGSTHTTLFPDSTTSSGI 2185

Query: 279  ---SSSSYGQHGS-----GSRQSLGHGRQGSGSR-QSPSHVRHGSGSGHSSSHGQHGSGS 329
               S+  +   GS         S   G QG  +  Q+     H + S  S++       +
Sbjct: 2186 VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEEST 2245

Query: 330  SYSYSRG-----HYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQA 384
            +Y  S G     H+ + S  TSG  +  +    S   S     S HS++ G+  ST+ + 
Sbjct: 2246 TYHRSPGSTPTTHFPASS-TTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRI 2304

Query: 385  S-----------SSGQHGSSSRQSSSYGQHES-------ASRHSSGRGQHSSGSGQSPG- 425
            S           S+   G S   ++ Y    S       AS  S G G+ S+ S   PG 
Sbjct: 2305 SPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGS 2364

Query: 426  -HGQRGSGSGQSPSSGQHGTGFGRSSSSG---------PYVSGSGYSSGFGHHESSSEHS 475
             H      S  +P   +  T    SS            P  S  G      H   +S H+
Sbjct: 2365 THSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHT 2424

Query: 476  SGYTQHGSGSG---------HSSGHGQHGSRSGQSSR--GERQGSSAGSSSSYGQHGSGS 524
            + +T+  + SG          S    Q G  +  ++   GE   +   SS S G   S +
Sbjct: 2425 TLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPA 2484

Query: 525  RQSL-GHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHG---YGSGRS-----SSRGPYE 575
            R +  G     + S  SPS +      GS  + S        Y S RS     S      
Sbjct: 2485 RSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 2544

Query: 576  SGSGHSSGLGHQESRSGQSSGYGQHGSSSG---HSST-HGQHGSTSGQ--SSSCGQHGAT 629
            SG    S   H +  S  ++ +    ++ G   HS+T H   GST      +S    G +
Sbjct: 2545 SGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPS 2604

Query: 630  SGQSSSHGQHGS-------GSSQSSRYGQQGSGSGQSPSRGRHGSDFGHS--SSYGQHGS 680
               ++SH   GS       GS+ +  +GQ+ +    SP    H + F  S  SS     S
Sbjct: 2605 QESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPG-STHTTLFPDSTTSSGIVEAS 2663

Query: 681  GSGWSSSNGPHGSVSGQSS---GFGHKSGSGQSSGYSQHGSGSSHSSG----------YR 727
                SS+  P  ++S  SS   G   +S + Q+   S H + S  S+           +R
Sbjct: 2664 TRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHR 2723

Query: 728  KHGSRSGQ----SSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGS 783
              GS        SS +  H   S +  S     SG+  SS H         + SR+  GS
Sbjct: 2724 SPGSTPTTHFPASSTTSGHSEKSTIFHS-SPDASGTTPSSAHSTTSGRGESTTSRISPGS 2782

Query: 784  SS-----GHSSSHGQHGSGTSCSSSCGHYESGSGQAS----GFGQHESGS-GQGYSQHGS 833
            +      G +++ G   + T+  SS     +    AS    G G+  + S  Q  S H +
Sbjct: 2783 TEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHST 2842

Query: 834  ASGHFSSQG--RHGSTSGQSSSSGQHDSS----SGQSSSYGQHESASHH----------- 876
             S   ++       ST+  SSS G  +++    S  +S  G+  +  H            
Sbjct: 2843 VSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFT 2902

Query: 877  ----ASGRGRHGSGSGQSPGHGQRG-------SGSGQSPSYGRHGSGSGRSSSSGRHGSG 925
                 SG     +    SP   Q G       +  G+  +     SGS  ++ S    + 
Sbjct: 2903 EDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTT 2962

Query: 926  SGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQ----------HGS 975
            SG   G    S    SS  T    GS  + S  +  +    S RS             G 
Sbjct: 2963 SGLV-GESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGV 3021

Query: 976  SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGS-------GSGQSSSYGPYR 1028
            S  SS+S+ Q GS    +       SG  Q P+ S    GS       GS  +SS G  +
Sbjct: 3022 SEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLG--Q 3079

Query: 1029 SGSGWSSSRGPYES----GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG--QHGST 1082
              + + SS G  E+        +SGL    + +  S+G   H + +  SST    Q  ST
Sbjct: 3080 QSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTG-SLHTTLTPASSTSAGLQEEST 3138

Query: 1083 SGQS---------SSCGQHGAS--------SGQSSSHGQHGSGSSQSSGYGRQGSGSGQS 1125
            + QS         S  G   A         S  SS+   H S SS + G   + +    S
Sbjct: 3139 TFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSS 3198

Query: 1126 PGHGQRGSGSRQSPSYGRHGS------GSGRSSSSGQHGS----GLGESSGFGHHE---- 1171
            PG         +S +    G        SG + ++   GS    GL E S   +      
Sbjct: 3199 PGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP 3258

Query: 1172 ---------SSSGQS--SSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYG 1220
                     +SSG S  S+ S    GS H++ +    +  G S       SS GS+    
Sbjct: 3259 DTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTL 3318

Query: 1221 QHGSGSRQSSG------HGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSS-SRGP 1273
              GS +  S G      H   GS            SGL  +S+     +GS  ++ S   
Sbjct: 3319 SPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAG 3378

Query: 1274 YESRSGHSSVFGQHESGSGHSSA------------YSQHGSGSG----HFCSQGQHGSTS 1317
              +R G S+ F    +    + A             + HGS S     HF +       S
Sbjct: 3379 STTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRS 3438

Query: 1318 GQSSTFDQEGSSTG---------------QSSSYGHRGSGSSQSSGYGRHGAGSGQSPSR 1362
             +S+T      +T                +S++Y H   GS+Q+  +      SG+    
Sbjct: 3439 EESTTVHSSPVATATTPSPARSTTSGLVEESTTY-HSSPGSTQTMHFPESDTTSGRGEES 3497

Query: 1363 GRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS-GSGQSSGFGHHESSSWQSSGCTQHGSGS 1421
                S + H+ S     + +     +  H S GS  ++ F    ++S +S   T   S  
Sbjct: 3498 TTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ 3557

Query: 1422 GHSSSYEQHGSRSGQSSRGERHGS--SSGSSSSYGQHGSGSRQSLGH------------- 1466
              + +       +     GE   S  SSGS  +    GS +   L               
Sbjct: 3558 DATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPA 3617

Query: 1467 ------GQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGL 1520
                      SG  +  + S  R GS    +   S    G    S+      GS+ ++ L
Sbjct: 3618 TTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLL 3677

Query: 1521 GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS 1580
                + SG S       SSSG + T    GST+  S         S   S+H      S+
Sbjct: 3678 PASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDST 3737

Query: 1581 QSSGY----GRQGSGSGQ-----SPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGL 1631
             SSG      R  S +G      SP          +S ++  H + +  + S     +  
Sbjct: 3738 TSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAP 3797

Query: 1632 GESSGFGHHESSSGQSSSYSQHGSGSGHS------------SGYGQHGSRSGQSSRGERH 1679
             E S   H    S  ++ +    + SGHS            SG     + S  S RGE  
Sbjct: 3798 VEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGEST 3857

Query: 1680 GSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSS 1739
             S     S       GS  + G     +    SP      S     S       G G  S
Sbjct: 3858 TSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPR-----SPTTTLSPASMTSLGVGEES 3912

Query: 1740 SRGPYESRSGHSSVFGQHESGSGHS-SAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGS 1798
            +    +  S HS+V     +  G S  + + + S  G   +     ST+      +    
Sbjct: 3913 TTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTF 3972

Query: 1799 STGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHG-------SGSGHSSSYGQHGSG 1851
             +  +S+H    +  S +S   ++ +    SP+  + G       +  G  S+     SG
Sbjct: 3973 HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSG 4032

Query: 1852 SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQ----HGSRSGQS 1907
            S  +  S    + SG          S   +   T  GS +  S S +        RS  +
Sbjct: 4033 STGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA 4092

Query: 1908 SRGEQHGSSSG----SSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSS 1963
            +      +SSG    SS+S+ Q GS    +       SG  Q P+ S    GS     S 
Sbjct: 4093 TLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSP 4152

Query: 1964 YGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSAS 2023
                 S  G  S+      G   ++ L      SG         S+  HSST   H + +
Sbjct: 4153 GSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGL-----VEASTPTHSSTGSLHTTLT 4207

Query: 2024 GQSSSCG--QHGASSGQS--SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSP 2079
              SS+    Q  +++ QS  SS     S  S ++      +     P        S  S 
Sbjct: 4208 PASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASST 4267

Query: 2080 SYGRHGSGSGRSSSSGQHG----PGLGESSGFGHHESSSGQSSSYSQHGS--GSGHSSGY 2133
            + GR    +   SS G  G    P    +S      ++S  SS  ++  +  GS  ++G 
Sbjct: 4268 TLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGL 4327

Query: 2134 GQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGS--GSGHSPSRGRHGSG 2191
             +  +    S R      S  S++     G     ++ H R GS   +    S    G  
Sbjct: 4328 SEKSTTFYSSPRSPDTTLSPASTT---SSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVS 4384

Query: 2192 SGHSSSHGQHGS-------GSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS 2244
               ++SH   GS       GS  +SS GP ES + HSS       GS  ++    + + S
Sbjct: 4385 QESTASHSSPGSTDTTLSPGSTTASSLGP-ESTTFHSS------PGSTETTLLPDNTTAS 4437

Query: 2245 GHF-CSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRG 2303
            G    S   H ST    +T    GS+T Q            +S+++    +    +P+  
Sbjct: 4438 GLLEASTPVHSSTGSPHTTLSPAGSTTRQ-----------GESTTFQSWPNSKDTTPAPP 4486

Query: 2304 RHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHES---SSWQSSGYTQHGSG 2360
               S     S+   HGS    SS+   H S S  + G     +   SS  ++  T   + 
Sbjct: 4487 TTTSAFVELST-TSHGSP---SSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPAR 4542

Query: 2361 SGHSSSYEQHGS-RSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSP-- 2417
            S  S   E+  +  S   S    H   S ++S  G+  + S  S  H    + S  S   
Sbjct: 4543 STTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALV 4602

Query: 2418 SPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHG 2477
                  H S    ++++ P  S +   S        S  ++G     +RS  S   G+  
Sbjct: 4603 EEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGEST 4662

Query: 2478 S---SSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ 2534
            +   SSG   T    GST+    S       S  SS+   H S SS + G   + +    
Sbjct: 4663 TSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHS 4722

Query: 2535 SPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGS-GLGESSGFGHHESSSGQSSSYSQH 2593
            SP        +  +PS  R  +      S+  H S G  ++  F    ++SG+S      
Sbjct: 4723 SP------VATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTS 4776

Query: 2594 GSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSP 2653
             S + H+       + S        + SS GS +    H   S  +SG   + + S  SP
Sbjct: 4777 HSSTTHTIS-SPPSTTSALVEEPTSYHSSPGSIA--TTHFPESSTTSGRSEESTASHSSP 4833

Query: 2654 SRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSS 2692
                      H ++ G+    +    S G  E+ L  ++
Sbjct: 4834 DTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTA 4872



 Score =  153 bits (387), Expect = 2e-36
 Identities = 467/2108 (22%), Positives = 750/2108 (35%), Gaps = 260/2108 (12%)

Query: 176  SSSYGEQNSDSHQSSGR--------GQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQ 227
            SS   E++S SH   G             SG  Q P      S S Q S+  T   GS  
Sbjct: 3018 SSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPT----ASHSSQGSTEATLSPGSTT 3073

Query: 228  SSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQ-HGSRSGQSSRGERHRS-SSGSSSSYG- 284
            +S   Q  ++   S G ++       +   G    S    SS G  H + +  SS+S G 
Sbjct: 3074 ASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGL 3133

Query: 285  QHGSGSRQSLGHGRQGS----GSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRG---- 336
            Q  S + QS       +    G+  +P  V     S  SS+   H S SS +  R     
Sbjct: 3134 QEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEEST 3193

Query: 337  --HYESGSGQTSGFGQHESGS---GQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHG 391
              H   G+  T+ F    + S   G+ +  S   SGS  +++     +T+G +  S    
Sbjct: 3194 TVHSSPGATGTALFPTRSATSVLVGEPTT-SPISSGSTETTALPGSTTTAGLSEKSTTFY 3252

Query: 392  SSSRQ----------SSSYGQHESASRHSSGRGQHSS---GSGQSPGHGQRGSGSGQSPS 438
            SS R           +SS    ES + HS     H++   GS   PG  Q  + S  SP 
Sbjct: 3253 SSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPG 3312

Query: 439  SGQHGTGFGRSSSSGPYVSGSGYSSGFGHHE----------------SSSEHSSGYTQHG 482
            S       G +++S      + + SG G  E                S+  HSS  + H 
Sbjct: 3313 STDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHT 3372

Query: 483  SGSGHSSGHGQHGSRSGQSSRGERQGSSAG----------SSSSYGQ-------HGSGSR 525
            + S   S   Q  S + QS    +  + A           S++S+G        H S S 
Sbjct: 3373 TLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASS 3432

Query: 526  QSLGHSRHGS-------GSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGS 578
             +LG S   +        +  +PSP+R        +S++Y      S   S++  +   S
Sbjct: 3433 TTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYH-----SSPGSTQTMHFPES 3487

Query: 579  GHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQ 638
              +SG G + + S  S+    H  SS  S+T       +   SS G    T    SS   
Sbjct: 3488 DTTSGRGEESTTSHSST---THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTS 3544

Query: 639  HGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQS 698
              S  S +S   Q  +G+   P+R       G S++       SG   +    GS +  +
Sbjct: 3545 GRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT---SPISSGSMETTALPGSTT--T 3599

Query: 699  SGFGHKSGSGQSSGYSQHGS---GSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQH 755
             G   KS +  SS  S   +    S+ SSG  +  + S     S     ++    S    
Sbjct: 3600 PGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTH---TTAFPDSTTTP 3656

Query: 756  GSGSHQSSGHGRQGSGSGH--SPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQ 813
            G   H ++ H   GS        S    GSS   ++SH   GS  +  S       GS  
Sbjct: 3657 GLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSP------GSTT 3710

Query: 814  ASGFGQHESG--SGQG------YSQHGSASGHFSSQGRHGSTSGQ-----SSSSGQHDSS 860
            A  FGQ  +   S  G      +    ++SG   +  R  S++G      S +S      
Sbjct: 3711 ALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL 3770

Query: 861  SGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSG 920
             G+S+++  H +++H         +   +      R  GS  +  +    + SG S  S 
Sbjct: 3771 QGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKST 3830

Query: 921  RHGSG---SGQSSGFGHKSSSGQSSGYTQHGS-GSGHSSSYEQHGSRSGQSSRSEQHGSS 976
               S    SG +    H ++SG+    T   S GS   ++     +  G S  S    SS
Sbjct: 3831 IFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSS 3890

Query: 977  SGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSS 1036
              S ++       S  SLG G+  + S   P  +       S  +       S + +SSS
Sbjct: 3891 PRSPTT--TLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSE-ESTTVYSSS 3947

Query: 1037 RGPYESG---SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG---QHGSTSGQSSSCG 1090
             G  E+       ++ +   E  +  S     H +     ST     +  +    S +  
Sbjct: 3948 PGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAST 4007

Query: 1091 QHG-------ASSGQSSSHGQHGSGS---------SQSSGYGRQGSGSGQSPGHGQRGS- 1133
            Q G       A  G+ S+     SGS         S +SG   + + S  SP   +  + 
Sbjct: 4008 QTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTL 4067

Query: 1134 -GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 1192
             GS  +PS     +    S  S         ++  G  E SS   +S+SQ   GS H++ 
Sbjct: 4068 PGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESS---TSHSQ--PGSTHTTA 4122

Query: 1193 YGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHG--- 1249
            +    + SG S       SS GS+        GS  +S  G+Q +    SP         
Sbjct: 4123 FPDSTTTSGLSQEPTTSHSSQGSTE--ATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP 4180

Query: 1250 -----SGLGHSSSHGQHGSGSGRSSSRGPYESRSG---HSSVFGQHESGSGHSSAYSQHG 1301
                 SGL  +S+     +GS  ++      + +G    S+ F    S S  + +     
Sbjct: 4181 DDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTT 4240

Query: 1302 SGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQS--SSYGHRGSGSSQSSGYGRHGAGSGQ- 1358
            +      +      +S  ++ F    ++ G+S  S+  H   G++ ++ +    A S   
Sbjct: 4241 AVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLV 4300

Query: 1359 -SPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGF---GHHESSSWQSSGC 1414
              P+     SGS  +++     + +G S  S    S               SS       
Sbjct: 4301 GEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEEST 4360

Query: 1415 TQHGS-GSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1473
            T H   GS H++++    +  G S       SS GS+ +    GS +  SLG        
Sbjct: 4361 TSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLG-------- 4412

Query: 1474 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYES--GSSHSSGLGHRESRSGQSS 1531
               P  +      GS +++      + SG   +  P  S  GS H++      S +G ++
Sbjct: 4413 ---PESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTT-----LSPAGSTT 4464

Query: 1532 GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG 1591
              G+        ST  Q    S  ++       S+    S   HGS SS  + +    S 
Sbjct: 4465 RQGE--------STTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHF---SA 4513

Query: 1592 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS 1651
            S  + G  +  +    SP          RS++SG     L E S   H    S   S+ +
Sbjct: 4514 SSTTLGRSEESTTVHSSPVATATTPSPARSTTSG-----LVEESTTYH----SSPGSTQT 4564

Query: 1652 QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQ 1711
             H   S  +SG G+  + S  SS      S+  ++S   +  +    S G          
Sbjct: 4565 MHFPESNTTSGRGEESTTS-HSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDS 4623

Query: 1712 SPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHG 1771
            S + GR        SS  Q  +G+    +R       G S+      SGS  ++A     
Sbjct: 4624 STTSGRSEESTASHSS--QDATGTIVLPARSTTSVLLGESTT-SPISSGSMETTALPGST 4680

Query: 1772 SGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPS 1831
            +  G           S +S+TF    SST  +     H S SS +    ++ +    SP 
Sbjct: 4681 TTPG----------LSEKSTTFHSSPSSTPTT-----HFSASSTTLGRSEESTTVHSSPV 4725

Query: 1832 RGRHGSGSGHSSSYGQHGSGSGWSSSSGR----HGSGSGQSSGFGHHESSSWQSSGYTQH 1887
                      S++ G     + + SS G     H   S  +SG      +S  S+ +T  
Sbjct: 4726 ATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTIS 4785

Query: 1888 GSGSGHSSSYEQHGS-RSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQS 1946
               S  S+  E+  S  S   S    H   S ++S   +  + S  S         +G +
Sbjct: 4786 SPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSS------PDTNGIT 4839

Query: 1947 PSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQH 2006
            P P+         +S+++         + +      G    S + +  SRS   +     
Sbjct: 4840 PLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQT---LS 4896

Query: 2007 GSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ-- 2064
             +S   SS  G+  S   Q+ S   H  +   S++     SG SQ S       GS +  
Sbjct: 4897 PASMTSSSISGEPTSLYSQAEST--HTTAFPASTTT----SGLSQESTTFHSKPGSTETT 4950

Query: 2065 -SPGHGQRGSGSRQ-SPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQ 2122
             SPG     S +++ +  + + GS     S +    PGL E S   +    S +++++S 
Sbjct: 4951 LSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSH 5010

Query: 2123 HGSGSGHS 2130
              + S HS
Sbjct: 5011 SNTMSIHS 5018



 Score = 40.4 bits (93), Expect = 0.025
 Identities = 70/339 (20%), Positives = 119/339 (35%), Gaps = 33/339 (9%)

Query: 169  HNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGS-GSGQ 227
            H S S  +    E+++  H S         +  +P+  +  +      S   H S GS Q
Sbjct: 4703 HFSASSTTLGRSEESTTVHSSP------VATATTPSPARSTTSGLVEESTAYHSSPGSTQ 4756

Query: 228  SSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHG 287
            +  F +  ++SG+S       S + H+       + S        + SS GS ++   H 
Sbjct: 4757 TMHFPESSTASGRSEESRTSHSSTTHTIS-SPPSTTSALVEEPTSYHSSPGSIAT--THF 4813

Query: 288  SGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYES---GSGQ 344
              S  + G   + + S  SP          H ++ G+    +++  S G  E+    +  
Sbjct: 4814 PESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTAT 4873

Query: 345  TSGFGQHES---GSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYG 401
            T G     +    S +S   +   +    SS  G+  S   QA S+      +  ++S  
Sbjct: 4874 TPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGL 4933

Query: 402  QHESASRHSSGRGQHSSGSGQSPG--------------HGQRGSGSGQSPSSGQHGTGFG 447
              ES + HS      S+ +  SPG              H Q GS       +     G  
Sbjct: 4934 SQESTTFHSK---PGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLS 4990

Query: 448  RSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSG 486
              S++     GS  ++ F H  + S HS   T      G
Sbjct: 4991 EESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPG 5029


>gi|171916097 repetin [Homo sapiens]
          Length = 784

 Score =  197 bits (500), Expect = 2e-49
 Identities = 238/805 (29%), Positives = 332/805 (41%), Gaps = 134/805 (16%)

Query: 1   MPKLLQGVITVIDVFYQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQS 60
           M +LL  +++VIDVF++YA  +G+   L K ELK+LL  EF  IL+ PNDP+TV+ IL  
Sbjct: 1   MAQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNL 60

Query: 61  LDRDHNKKVDFTEYLLMIFKLVQA-RNKIIGKDY----------------CQVSGSKLRD 103
           LD+D +  +DF EYLL++F+LVQA  +K+  K +                C+  G+  R 
Sbjct: 61  LDQDRDGHIDFHEYLLLVFQLVQACYHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQ 120

Query: 104 DTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQR 163
              +H+EE++ +   + +RQ+    H      + DS+        +    S   R    +
Sbjct: 121 HRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPER----Q 176

Query: 164 DFSGQHNSYSGQSSSY----GEQNSDSHQSSGRGQCGSGSGQSPNYGQ-HGSGSGQSSSN 218
           D    HN    Q   +     E+ S    S  +    S SGQ+   G        +    
Sbjct: 177 DRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQ 236

Query: 219 DTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSG 278
           D+H    GQS   +Q   + GQ+S ++Q  +    S  Y     R GQ   G       G
Sbjct: 237 DSH---YGQSERHTQQSETLGQASHFNQ--TNQQKSGSYCGQSERLGQ-ELGCGQTDRQG 290

Query: 279 SSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHY 338
            SS YGQ     RQ   +   G   RQ          S H S   + G  S YS      
Sbjct: 291 QSSHYGQ---TDRQDQSY-HYGQTDRQGQ--------SSHYSQTDRQGQSSHYS-----Q 333

Query: 339 ESGSGQTSGFGQHESGSGQSSGY---SKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSR 395
               GQ+S +GQ +   GQ   Y   ++ G GS +S    Q     GQ+S  GQ  +   
Sbjct: 334 PDRQGQSSHYGQMDR-KGQCYHYDQTNRQGQGSHYSQPNRQ-----GQSSHYGQPDTQD- 386

Query: 396 QSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPY 455
           QSS YGQ        + R   SS  GQ+   GQ  S   Q    GQ G+ +G++      
Sbjct: 387 QSSHYGQ--------TDRQDQSSHYGQTERQGQ-SSHYSQMDRQGQ-GSHYGQTDR---- 432

Query: 456 VSGSGYSSGFGHHESSSEHSS-GYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSS 514
               G SS +G  +   ++S  G T      G SS +GQ   R GQSS    Q    G S
Sbjct: 433 ---QGQSSHYGQPDRQGQNSHYGQTDR---QGQSSHYGQ-TDRQGQSSH-YSQPDKQGQS 484

Query: 515 SSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPY 574
           S YG+     RQ   +  +G   GQ  S   G+ +   RQ  S+    YG        P 
Sbjct: 485 SHYGKI---DRQDQSY-HYGQPDGQGQSSHYGQTD---RQGQSF---HYGQ-------PD 527

Query: 575 ESG-SGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQS 633
             G S H S    Q  R GQSS YGQ                  GQSS  GQ     GQS
Sbjct: 528 RQGQSSHYS----QMDRQGQSSHYGQ--------------TDRQGQSSHYGQTD-RQGQS 568

Query: 634 SSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGS 693
             +GQ      QSS Y Q  +G  Q  ++   G++    +SY +    SG  S   P G 
Sbjct: 569 YHYGQ-TDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTP-GQ 626

Query: 694 VSGQSSGFGHKSGSGQSSGY--------SQHGSGSSHSSGYRK----HGSRSGQSSRSEQ 741
              Q+ G G +S   Q +G+        SQH      +   ++    H  R  QS  SEQ
Sbjct: 627 EGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQ 686

Query: 742 HGSSSGLSSSYGQHGS-GSHQSSGH 765
               +    S+G+  S  + +  GH
Sbjct: 687 GHRQAQTRQSHGEGLSHWAEEEQGH 711



 Score =  134 bits (336), Expect = 2e-30
 Identities = 198/672 (29%), Positives = 259/672 (38%), Gaps = 100/672 (14%)

Query: 722  HSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSH----QSSGHGR--QGSGSGHS 775
            H    + HG R+ Q  R ++         + G+     H    Q+S H +  +  G  H 
Sbjct: 87   HKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHH 146

Query: 776  PSRVRHGSSSGHSSSHGQ----HGSGTSCSSSCGHYESGSGQASGFG-------QHESGS 824
                R    S H  S  Q    H S         H+     Q   F          +S S
Sbjct: 147  GQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSS 206

Query: 825  GQGYSQHGSASGHFSSQGRHGSTSG-----QSSSSGQHDSSSGQSSSYGQHESASH-HAS 878
            G+  S H S SG    QG   + +      Q S  GQ +  + QS + GQ   ASH + +
Sbjct: 207  GKKVS-HKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQ---ASHFNQT 262

Query: 879  GRGRHGSGSGQSPGHGQRGSGSGQSPSYGR--HGSGSGRSSSSGRHGSGS--GQSSGFGH 934
             + + GS  GQS   GQ   G GQ+   G+  H   + R   S  +G     GQSS +  
Sbjct: 263  NQQKSGSYCGQSERLGQE-LGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQ 321

Query: 935  KSSSGQSSGYTQHGSGSGHSSSYEQ-----------HGSRSGQSSRSEQHGSSSGSSSSY 983
                GQSS Y+Q     G SS Y Q             +R GQ S   Q  +  G SS Y
Sbjct: 322  TDRQGQSSHYSQPDR-QGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQP-NRQGQSSHY 379

Query: 984  GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPY-RSGSGWSSSRGPYES 1042
            GQ  +  + S     +G    Q  S   G+     GQSS Y    R G G   S      
Sbjct: 380  GQPDTQDQSS----HYGQTDRQDQSSHYGQT-ERQGQSSHYSQMDRQGQG---SHYGQTD 431

Query: 1043 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH 1102
              G SS  G  + R GQ+S YGQ     G SS +GQ     GQSS   Q     GQSS +
Sbjct: 432  RQGQSSHYGQPD-RQGQNSHYGQT-DRQGQSSHYGQT-DRQGQSSHYSQPD-KQGQSSHY 487

Query: 1103 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG---RHGSGSGRSSSSGQHGS 1159
            G+      QS  YG Q  G GQS  +GQ      QS  YG   R G  S  S    Q   
Sbjct: 488  GKIDR-QDQSYHYG-QPDGQGQSSHYGQTDRQG-QSFHYGQPDRQGQSSHYSQMDRQ--- 541

Query: 1160 GLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR--GERHGSSSGSSS 1217
              G+SS +G  +   GQSS Y Q     G S  YGQ   R GQSS     + G   G + 
Sbjct: 542  --GQSSHYGQTDRQ-GQSSHYGQTDR-QGQSYHYGQT-DRQGQSSHYIQSQTGEIQGQNK 596

Query: 1218 HYGQHGSGSRQSS---GHGRQGSGSGHSPSR-GRHGSGLGHSSSHGQHGSGSGRSSSRGP 1273
            ++ Q   G+R++S     GR G  S  +P + G    G G  S   Q    +G       
Sbjct: 597  YF-QGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQ---NGHQVWEPE 652

Query: 1274 YESRSGHSSVFGQHE----------------SGSGHSSAYSQ--HGSGSGHFCSQGQHGS 1315
             +S+     +  Q +                S  GH  A ++  HG G  H+  + Q   
Sbjct: 653  EDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQ 712

Query: 1316 TSGQSSTFDQEG 1327
            T  + S   QEG
Sbjct: 713  TWDRHSHESQEG 724



 Score =  130 bits (327), Expect = 2e-29
 Identities = 202/679 (29%), Positives = 265/679 (39%), Gaps = 96/679 (14%)

Query: 2110 HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRY---GQHGSGS 2166
            ++S  G++S   +   G+      G  G +  Q    ER  S      R      HG   
Sbjct: 91   NKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPE 150

Query: 2167 RQS--SGHG---RQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSG-- 2219
            RQ   S HG   +Q   S HS    R    S H+ S  Q    S   S R   +S SG  
Sbjct: 151  RQDRDSHHGQSEKQDRDSHHSQPE-RQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKK 209

Query: 2220 --HSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHG 2277
              H S  GQ +   GH  A ++        C +    S  GQS    Q+  + GQ+S   
Sbjct: 210  VSHKSTSGQAK-WQGHIFALNR--------CEKPIQDSHYGQSERHTQQSETLGQASHFN 260

Query: 2278 QHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS-- 2335
            Q  +   +S SY  Q    GQ    G+     G SS YGQ    +     S  +G     
Sbjct: 261  Q--TNQQKSGSYCGQSERLGQELGCGQTDR-QGQSSHYGQ----TDRQDQSYHYGQTDRQ 313

Query: 2336 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQ--------HGSRSGQSSRGERHGSSS 2387
            GQSS +   +    QSS Y+Q     G SS Y Q        H  ++ +  +G  +   +
Sbjct: 314  GQSSHYSQTDRQG-QSSHYSQPDR-QGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPN 371

Query: 2388 --GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPY---GSGSG 2442
              G SS YGQ  +  + S     +G    Q  S   G+     GQSS YS     G GS 
Sbjct: 372  RQGQSSHYGQPDTQDQSS----HYGQTDRQDQSSHYGQT-ERQGQSSHYSQMDRQGQGSH 426

Query: 2443 WSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQH 2502
            +  +        G SS  G  + R GQ+S YGQ     G SS +GQ     GQSS   Q 
Sbjct: 427  YGQT-----DRQGQSSHYGQPD-RQGQNSHYGQT-DRQGQSSHYGQT-DRQGQSSHYSQP 478

Query: 2503 GASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG---RHGSGSG 2559
                GQSS +G+      QS  YG Q  G GQS  +GQ      QS  YG   R G  S 
Sbjct: 479  D-KQGQSSHYGKIDR-QDQSYHYG-QPDGQGQSSHYGQTDRQG-QSFHYGQPDRQGQSSH 534

Query: 2560 RSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR--GE 2617
             S    Q     G+SS +G  +   GQSS Y Q     G S  YGQ   R GQSS     
Sbjct: 535  YSQMDRQ-----GQSSHYGQTDRQ-GQSSHYGQTDR-QGQSYHYGQT-DRQGQSSHYIQS 586

Query: 2618 RHGSSSGSSSHYGQHGSGSRQSS---GHGRQGSGSGQSPSR-GRHGSGLGHSSSHGQHGS 2673
            + G   G + ++ Q   G+R++S     GR G  S Q+P + G    G G  S   Q   
Sbjct: 587  QTGEIQGQNKYF-QGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNG 645

Query: 2674 GS------------GRSSSRGPYESRLGHSSVFGQH-ESGSGHSSAYSQ--HGSGSGHFC 2718
                           +  ++   E  L H     Q   S  GH  A ++  HG G  H+ 
Sbjct: 646  HQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWA 705

Query: 2719 SQGQHGSTSGQSSTFDQEG 2737
             + Q   T  + S   QEG
Sbjct: 706  EEEQGHQTWDRHSHESQEG 724



 Score =  127 bits (320), Expect = 1e-28
 Identities = 202/712 (28%), Positives = 260/712 (36%), Gaps = 117/712 (16%)

Query: 253 HSSGYGQHGSRSGQSSRGERHRSSSGSSSSYG-QHGSGSRQSLGHGRQGSGSRQS-PSHV 310
           H      HG R+ Q  RG+          + G QH     +   +       RQ   SH 
Sbjct: 87  HKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHH 146

Query: 311 RHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYS----KHGS 366
                    S HGQ     S    R  + S   +      H     Q   +S    +  S
Sbjct: 147 GQPERQDRDSHHGQ-----SEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQS 201

Query: 367 GSGHSSSQGQHGSTSGQASSSGQHGSSSR-----QSSSYGQHESASRHSSGRGQHS---- 417
               S  +  H STSGQA   G   + +R     Q S YGQ E  ++ S   GQ S    
Sbjct: 202 QDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQ 261

Query: 418 -----SGS--GQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHES 470
                SGS  GQS   GQ   G GQ+   GQ             Y  G     G   H S
Sbjct: 262 TNQQKSGSYCGQSERLGQE-LGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYS 320

Query: 471 SSEH---SSGYTQHGSGSGHSSGHGQ--------HGSRSGQSSRGER--QGSSAGSSSSY 517
            ++    SS Y+Q     G SS +GQ        H  ++ +  +G    Q +  G SS Y
Sbjct: 321 QTDRQGQSSHYSQPDR-QGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHY 379

Query: 518 GQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESG 577
           GQ  +  + S     +G    Q  S   G+ E    QSS Y       G+ S  G  +  
Sbjct: 380 GQPDTQDQSS----HYGQTDRQDQSSHYGQTERQG-QSSHYSQMDR-QGQGSHYGQTDR- 432

Query: 578 SGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHG 637
            G SS  G Q  R GQ+S YGQ     G SS +GQ     GQSS   Q     GQSS +G
Sbjct: 433 QGQSSHYG-QPDRQGQNSHYGQT-DRQGQSSHYGQT-DRQGQSSHYSQPDK-QGQSSHYG 488

Query: 638 QHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQ---HGSGSGWSSSNGPHGSV 694
           +      QS  YGQ   G GQS   G+     G S  YGQ    G  S +S  +      
Sbjct: 489 KIDR-QDQSYHYGQP-DGQGQSSHYGQTDRQ-GQSFHYGQPDRQGQSSHYSQMDR----- 540

Query: 695 SGQSSGFGHKSGSGQSSGYSQHG-SGSSHSSGYRKHGSRSGQSSRSEQ------------ 741
            GQSS +G     GQSS Y Q    G S+  G      R GQSS   Q            
Sbjct: 541 QGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQT---DRQGQSSHYIQSQTGEIQGQNKY 597

Query: 742 -HGSSSGLSSSY----GQHGSGSHQSSGH-GRQGSGSGHSPSRVRHGSSSGHS------- 788
             G+     +SY    G+ G  S Q+ G  G Q  G G      R    +GH        
Sbjct: 598 FQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQS---RDSQQNGHQVWEPEED 654

Query: 789 SSHGQHG----------------SGTSCSSSCGHYESGSGQASGFG-QHESGSGQGYSQH 831
           S H QH                    SCSS  GH ++ + Q+ G G  H +   QG+ Q 
Sbjct: 655 SQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGH-QT 713

Query: 832 GSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRH 883
                H S +G  G+   ++    Q+     + +   +HE  SH    R  H
Sbjct: 714 WDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTH--EHEQ-SHQRRDRQTH 762



 Score =  124 bits (311), Expect = 1e-27
 Identities = 199/679 (29%), Positives = 260/679 (38%), Gaps = 96/679 (14%)

Query: 1640 HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRY---GQHGSGS 1696
            ++S  G++S   +   G+      G  G +  Q    ER  S      R      HG   
Sbjct: 91   NKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPE 150

Query: 1697 RQS--SGHGRQGSGSGQS----PSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSG- 1749
            RQ   S HG+       S    P R    S   H+ S  Q    S   S R   +S SG 
Sbjct: 151  RQDRDSHHGQSEKQDRDSHHSQPERQDRDSH--HNQSERQDKDFSFDQSERQSQDSSSGK 208

Query: 1750 ---HSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSH 1806
               H S  GQ +   GH  A ++        C +    S  GQS    Q+  + GQ+S  
Sbjct: 209  KVSHKSTSGQAK-WQGHIFALNR--------CEKPIQDSHYGQSERHTQQSETLGQASHF 259

Query: 1807 GQ-----HGSGSSQSSSYGQQGSGSGQSPSRGR---HGSGSGHSSSYGQHGSGSGWSSSS 1858
             Q      GS   QS   GQ+  G GQ+  +G+   +G       SY    +     SS 
Sbjct: 260  NQTNQQKSGSYCGQSERLGQE-LGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSH 318

Query: 1859 GRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSG 1918
                   GQSS +   +    QSS Y Q     G    Y+Q  +R GQ S   Q  +  G
Sbjct: 319  YSQTDRQGQSSHYSQPDRQG-QSSHYGQMDR-KGQCYHYDQT-NRQGQGSHYSQP-NRQG 374

Query: 1919 SSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPY---GSGSGWSS 1975
             SS YGQ  +  + S     +G    Q  S   G+     GQSS Y      G GS +  
Sbjct: 375  QSSHYGQPDTQDQSS----HYGQTDRQDQSSHYGQT-ERQGQSSHYSQMDRQGQGSHYGQ 429

Query: 1976 SRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGAS 2035
            +        G SS  G  + R GQ+S YGQ     G SS +GQ     GQSS   Q    
Sbjct: 430  T-----DRQGQSSHYGQPD-RQGQNSHYGQT-DRQGQSSHYGQT-DRQGQSSHYSQPD-K 480

Query: 2036 SGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG---RHGSGSGRSS 2092
             GQSS +G+      QS  YG Q  G GQS  +GQ      QS  YG   R G  S  S 
Sbjct: 481  QGQSSHYGKIDR-QDQSYHYG-QPDGQGQSSHYGQTDRQG-QSFHYGQPDRQGQSSHYSQ 537

Query: 2093 SSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR--GERHG 2150
               Q     G+SS +G  +   GQSS Y Q     G S  YGQ   R GQSS     + G
Sbjct: 538  MDRQ-----GQSSHYGQTDRQ-GQSSHYGQTDR-QGQSYHYGQT-DRQGQSSHYIQSQTG 589

Query: 2151 SSSGSSSRYGQHGSGSRQSS---GHGRQGSGSGHSPSR-GRHGSGSGHSSSHGQHGSGSG 2206
               G + +Y Q   G+R++S     GR G  S  +P + G    G G  S   Q    +G
Sbjct: 590  EIQGQN-KYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQ---NG 645

Query: 2207 RSSSRGPYESRSGHSSVFGQHE----------------SGSGHSSAYSQ--HGSGSGHFC 2248
                    +S+     +  Q +                S  GH  A ++  HG G  H+ 
Sbjct: 646  HQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWA 705

Query: 2249 SQGQHGSTSGQSSTFDQEG 2267
             + Q   T  + S   QEG
Sbjct: 706  EEEQGHQTWDRHSHESQEG 724



 Score =  115 bits (288), Expect = 6e-25
 Identities = 182/679 (26%), Positives = 239/679 (35%), Gaps = 109/679 (16%)

Query: 1893 HSSSYEQHGSRSGQSSRGEQHGSS----SGSSSSYGQHGSGSRQSLGHGQ--HGSGSGQS 1946
            H    + HG R+ Q  RG++          +   + Q     RQ+  H Q     G    
Sbjct: 87   HKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHH 146

Query: 1947 PSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQH 2006
              P R    S  GQS             S     +  S H+      +  S   S     
Sbjct: 147  GQPERQDRDSHHGQSEKQ----DRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQ 202

Query: 2007 GSSSGHSSTHGQHGSASGQSSSCGQ-----------HGASSGQSSSHGQHGSGSSQSSGY 2055
             SSSG   +   H S SGQ+   G              +  GQS  H Q      Q+S +
Sbjct: 203  DSSSGKKVS---HKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHF 259

Query: 2056 G-----RQGSGSGQSPGHGQR-GSGSRQSPSYGRHGSGSGRSSSSGQHG--PGLGESSGF 2107
                  + GS  GQS   GQ  G G         H   + R   S  +G     G+SS +
Sbjct: 260  NQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHY 319

Query: 2108 GHHESSSGQSSSYSQHGSGSGHSSGYGQ--------HGSRSGQSSRGERHG--SSSGSSS 2157
               +   GQSS YSQ     G SS YGQ        H  ++ +  +G  +   +  G SS
Sbjct: 320  SQTD-RQGQSSHYSQ-PDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSS 377

Query: 2158 RYGQHGSGSRQSSGHGR--QGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYE 2215
             YGQ  +   QSS +G+  +   S H     R G  S H S   + G GS    +     
Sbjct: 378  HYGQPDT-QDQSSHYGQTDRQDQSSHYGQTERQGQ-SSHYSQMDRQGQGSHYGQT----- 430

Query: 2216 SRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 2275
             R G SS +GQ +   G +S Y Q     G     GQ     GQSS + Q     GQSS 
Sbjct: 431  DRQGQSSHYGQPDR-QGQNSHYGQ-TDRQGQSSHYGQ-TDRQGQSSHYSQP-DKQGQSSH 486

Query: 2276 HGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQ---HGSGSGWSSSSGRHG 2332
            +G+      QS  YGQ   G GQS   G+     G S  YGQ    G  S +S    +  
Sbjct: 487  YGKI-DRQDQSYHYGQP-DGQGQSSHYGQ-TDRQGQSFHYGQPDRQGQSSHYSQMDRQ-- 541

Query: 2333 SGSGQSSGFGHHESSSWQSS-GYTQHGSGSGHSSSYEQHGSRSG--QSSRGERHGSSSGS 2389
               GQSS +G  +     S  G T     S H    ++ G  S   QS  GE  G     
Sbjct: 542  ---GQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQG----- 593

Query: 2390 SSSYGQHGSGSRQSL---GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSS 2446
             + Y Q   G+R++      G+ G  S Q+P    G    G G  S  S       W   
Sbjct: 594  QNKYFQGTEGTRKASYVEQSGRSGRLSQQTPG-QEGYQNQGQGFQSRDSQQNGHQVWE-- 650

Query: 2447 RGPYESGSGH------------------------SSGLGHRESRSGQSSGYG-QHGSSSG 2481
              P E    H                        SS  GHR++++ QS G G  H +   
Sbjct: 651  --PEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEE 708

Query: 2482 HSSTHGQHGSTSGQSSSCG 2500
                     S   Q   CG
Sbjct: 709  QGHQTWDRHSHESQEGPCG 727



 Score =  115 bits (287), Expect = 8e-25
 Identities = 163/587 (27%), Positives = 220/587 (37%), Gaps = 62/587 (10%)

Query: 2266 EGSSTGQSSSHGQHGSGSSQSSSY----GQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSG 2321
            +  S G  +S  + G   +Q   +    G+Q     +   +  H S          HG  
Sbjct: 90   DNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQP 149

Query: 2322 SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGE 2381
                  S  HG    Q     H +        +           S++Q   +S  SS G+
Sbjct: 150  ERQDRDS-HHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGK 208

Query: 2382 R--HGSSSGSSSSYGQHGSGSR-----QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY 2434
            +  H S+SG +   G   + +R     Q   +GQ    + QS +  +  H + + Q  S 
Sbjct: 209  KVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSG 268

Query: 2435 SPYGSGSGWSSSRGPYESG-SGHSSGLGHRESRSGQSSGYGQ---HGSSSGHSSTHGQHG 2490
            S  G         G  ++   G SS  G  + R  QS  YGQ    G SS +S T  Q  
Sbjct: 269  SYCGQSERLGQELGCGQTDRQGQSSHYGQTD-RQDQSYHYGQTDRQGQSSHYSQTDRQ-- 325

Query: 2491 STSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGY---GRQGSGSGQSPGHGQRGSGSRQ 2547
               GQSS   Q     GQSS +GQ      Q   Y    RQG GS  S  + Q  S    
Sbjct: 326  ---GQSSHYSQPDRQ-GQSSHYGQMDR-KGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYG 380

Query: 2548 SPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHG 2607
             P      S  G++    Q       SS +G  E   GQSS YSQ     G  S YGQ  
Sbjct: 381  QPDTQDQSSHYGQTDRQDQ-------SSHYGQTERQ-GQSSHYSQMDR-QGQGSHYGQT- 430

Query: 2608 SRSGQSS---RGERHGSSS--------GSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRG 2656
             R GQSS   + +R G +S        G SSHYGQ  +  +  S H  Q    GQS   G
Sbjct: 431  DRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQ--TDRQGQSSHYSQPDKQGQSSHYG 488

Query: 2657 RHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQ--HGSGS 2714
            +        S H     G G+SS  G  + R G S  +GQ +   G SS YSQ      S
Sbjct: 489  KIDRQ--DQSYHYGQPDGQGQSSHYGQTD-RQGQSFHYGQPDR-QGQSSHYSQMDRQGQS 544

Query: 2715 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGR 2774
             H+    + G +S    T  Q     GQS  YG       QSS Y +   G  Q  +   
Sbjct: 545  SHYGQTDRQGQSSHYGQTDRQ-----GQSYHYGQTDR-QGQSSHYIQSQTGEIQGQNKYF 598

Query: 2775 HGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDG 2821
             G+   + +SY +    SG+ S  +    G    G  +    S  +G
Sbjct: 599  QGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNG 645



 Score =  108 bits (269), Expect = 1e-22
 Identities = 196/694 (28%), Positives = 252/694 (36%), Gaps = 128/694 (18%)

Query: 1072 HSSTHGQHGSTSGQSSSCGQHGASS-----GQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 1126
            H   +  HG  + Q    GQ GA            H Q      Q+S + +     G S 
Sbjct: 87   HKLDNKSHGGRTSQQER-GQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSH 145

Query: 1127 GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG 1186
             HGQ     R S     HG    +   S  H S         HH  S  Q   +S     
Sbjct: 146  -HGQPERQDRDS----HHGQSEKQDRDS--HHSQPERQDRDSHHNQSERQDKDFS----- 193

Query: 1187 SGHSSGYGQHGSRSGQSSRGER--HGSSSGSS------------------SHYGQHGSGS 1226
                  + Q   +S  SS G++  H S+SG +                  SHYGQ    +
Sbjct: 194  ------FDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHT 247

Query: 1227 RQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQ 1286
            +QS   G+  +   +  ++ + GS  G S   GQ   G G++        R G SS +GQ
Sbjct: 248  QQSETLGQ--ASHFNQTNQQKSGSYCGQSERLGQE-LGCGQTD-------RQGQSSHYGQ 297

Query: 1287 --HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGH--RGSG 1342
               +  S H     + G  S +  +  Q     GQSS + Q     GQSS YG   R   
Sbjct: 298  TDRQDQSYHYGQTDRQGQSSHYSQTDRQ-----GQSSHYSQPDRQ-GQSSHYGQMDRKGQ 351

Query: 1343 SSQSSGYGRHGAGSGQS-PSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGF 1401
                    R G GS  S P+R       G SS YGQ  +     SS         QSS +
Sbjct: 352  CYHYDQTNRQGQGSHYSQPNR------QGQSSHYGQPDTQD--QSSHYGQTDRQDQSSHY 403

Query: 1402 GHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSS---RGERHGSSS--------GSS 1450
            G  E    QSS  +Q     G  S Y Q   R GQSS   + +R G +S        G S
Sbjct: 404  GQTERQG-QSSHYSQMDR-QGQGSHYGQT-DRQGQSSHYGQPDRQGQNSHYGQTDRQGQS 460

Query: 1451 SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGS--GSGWSSSRG 1508
            S YGQ     + S  H       GQS       +G    Q  SY  YG   G G SS  G
Sbjct: 461  SHYGQTDRQGQSS--HYSQPDKQGQS-----SHYGKIDRQDQSYH-YGQPDGQGQSSHYG 512

Query: 1509 PYE-SGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSG 1567
              +  G S   G   +  R GQSS Y Q     G SS +GQ     GQSS  GQ     G
Sbjct: 513  QTDRQGQSFHYG---QPDRQGQSSHYSQM-DRQGQSSHYGQT-DRQGQSSHYGQTDRQ-G 566

Query: 1568 QSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSS--SSG 1625
            QS  +GQ      QSS Y +  +G  Q      +G+   +  SY      SGR S  + G
Sbjct: 567  QSYHYGQTDR-QGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPG 625

Query: 1626 QHG---SGLG----ESSGFGHHESSSGQSSSYSQH-------------GSGSGHSSGYGQ 1665
            Q G    G G    +S   GH      + S + QH               G    S   +
Sbjct: 626  QEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSE 685

Query: 1666 HGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQS 1699
             G R  Q+ +    G S  +    G H +  R S
Sbjct: 686  QGHRQAQTRQSHGEGLSHWAEEEQG-HQTWDRHS 718



 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 62/240 (25%), Positives = 80/240 (33%), Gaps = 23/240 (9%)

Query: 2599 HSSGYGQHGSRSGQSSRGERHGSS----SGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPS 2654
            H      HG R+ Q  RG+           +   + Q     RQ+S H +     G S  
Sbjct: 87   HKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDS-- 144

Query: 2655 RGRHGSG--LGHSSSHGQHGSGSGRSSSRGP--YESRLGHSSVFGQHESGSGHSSAYSQH 2710
               HG        S HGQ       S    P   +    H+    Q +  S   S     
Sbjct: 145  --HHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQ 202

Query: 2711 GSGSGHFCSQGQHGSTSGQSSTFDQ-----EGSSTGQSSSYGHRGSGSSQSSGYGRHGAG 2765
             S SG   S   H STSGQ+                Q S YG     + QS   G+  A 
Sbjct: 203  DSSSGKKVS---HKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQ--AS 257

Query: 2766 SGQSLSHGRHGSGSGQSSSYGQH-GSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSS 2824
                 +  + GS  GQS   GQ  G G     G S H   + +   SY  G ++  G SS
Sbjct: 258  HFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSS 317


>gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo
            sapiens]
          Length = 1067

 Score =  181 bits (458), Expect = 1e-44
 Identities = 261/1028 (25%), Positives = 353/1028 (34%), Gaps = 134/1028 (13%)

Query: 521  GSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGH 580
            GSGSR    H   G GS     PS+GR + G   +  +    Y +     RGP       
Sbjct: 100  GSGSRSRFSHRTRGGGSSPQRPPSQGRPDDGRGYAGYFDLWPYRAPMPRKRGPPPRHWAS 159

Query: 581  SSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHG----STSGQSSSCGQHGATSGQSSSH 636
                    S    S G G  G +   S   G  G      +G         ++  +    
Sbjct: 160  PPHKRATPSSLAHSVGCGMRGKAPTVSGQDGYSGLQPRRWAGPPHKRAVPRSSLARIGGS 219

Query: 637  GQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDF-----GHSSSYGQHGSGSGWSSSNGPH 691
            G  G   +   + G  G    +     R   DF      +S  Y  H S   +    G  
Sbjct: 220  GMPGKAPAVWGQDGYSGPRVREPLPPCRDPGDFVPALRDYSRRYYGHSSVPDYRPLRG-- 277

Query: 692  GSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSS 751
                G  +G+      G+   Y+ H S  S+    + +G   G +       S  G    
Sbjct: 278  ---DGNQNGY-----RGRDHEYTDHPSKGSYREPLKSYGGPCGAAPVWGTPPSYGG-GCR 328

Query: 752  YGQHGSGSHQSSGHGRQGS----------GSGHSPSRVRHGSSSGHSSSHGQHGSGTSCS 801
            Y ++   S  +   GR                HSP     G S   SSS+G   S     
Sbjct: 329  YEEYQGNSPDACSEGRSSEALPVVLPDAYSRDHSPKAYSGGRS---SSSNGYSRSDRYGE 385

Query: 802  SSC-GHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSS-QGRHGSTSGQSSSSGQHDS 859
              C   Y   S  A   G++ S +  G S H    G +   +GR         S+  H  
Sbjct: 386  EGCYEEYRGRSPDAHSGGRNSSSNSYGQSHHYGGEGRYEEYRGRSHEARSGGRSTDAHSR 445

Query: 860  SSGQSSSYGQHESASHH--ASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSS 917
                 +  G H+S+S      G GR+    G+S       +  G SP    +  G   SS
Sbjct: 446  GRSDDAYSGGHDSSSWSDCCGGGGRYEEYQGRS----LDANSGGCSPE--AYSGGHDNSS 499

Query: 918  SSGRHGSGSGQSSGFGHK--SSSGQSSGYTQHGSGSGHSSSYEQ---HGSRSGQSSRSEQ 972
             S R+G G       GH   ++SG  S  T  G  S  S+SY Q   +G       R   
Sbjct: 500  WSDRYGVGGHYEENRGHSLDANSGGRSPDTHSGGHSSSSNSYGQSHRYGGEGRYEYRGRS 559

Query: 973  HGSSSG------------SSSSYGQHGSGS--RQSLGHGQHGSGSGQSPSPSRGRHGSGS 1018
            H + SG            SSS   ++G G    +  G     +  G+SP+   G H S S
Sbjct: 560  HDAHSGGCSADAYSGGHDSSSQSNRYGGGGCYEEYRGRSLDANSGGRSPNAYSGGHDSSS 619

Query: 1019 -----GQSSSYGPYRSGS--GWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG 1071
                 G    Y  YR  S    S  R P     GH S        SGQS+ YG  G    
Sbjct: 620  WSHRYGGGGRYEEYRGRSLDANSGGRSPDAYSGGHDS--------SGQSNCYGGGGR--- 668

Query: 1072 HSSTHGQ--HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHG 1129
            +    G+    ++ G+S      G  S   S+    G    +  G+    +  G+SP   
Sbjct: 669  YEEYRGRLLDANSGGRSPDAYSGGHDSSSQSNRYGGGGRYEEYRGHSLDANSGGRSPDTY 728

Query: 1130 QRG-SGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSG 1188
             RG   S QS  YG    G GRS  +         SSG      S G  SS   H  G G
Sbjct: 729  SRGHDSSSQSDHYG----GGGRSLDA--------NSSGRLPDAYSGGHDSSSRSHRYGGG 776

Query: 1189 HSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQS--SGHGRQGSGSGHSPSRG 1246
                Y ++  RS  ++ G R       +++ G H S SR     G GR     GHS    
Sbjct: 777  --GRYEEYRGRSLDANSGGR-----SPNAYSGGHNSSSRNDPCRGGGRYEENRGHSLD-- 827

Query: 1247 RHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGH 1306
                   +S  H  +    GR SS   Y+ RS      G +E   G S  +  H  G   
Sbjct: 828  ------ANSGGHSPNAYSGGRDSSSNSYD-RSHRYGGGGHYEEYRGRS--HDTHSRGRSP 878

Query: 1307 FCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSS-QSSGYGRHGAGSGQSPSRGRH 1365
                G H  T   S   D   +S G+S  YG  G     Q      +G G G + S   H
Sbjct: 879  DAHSGDH-YTEAYSRGRDSFSNSYGRSDHYGRGGCYEEYQGRSPNAYGGGRGLNSSNNSH 937

Query: 1366 GSGS--GHSSSYGQHGSGSGWSSSSGRHGS-----GSGQSSGFGHHE----SSSWQSSGC 1414
            G     G    Y ++   S  + S GR  S      S +  G GH+E    S     SG 
Sbjct: 938  GRSHRYGGGGRYEEYRGPSPDAHSGGRDSSIKSYGLSDRYGGGGHYEEYQGSLPDAYSGD 997

Query: 1415 TQHGSGS-GHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHG-SGSRQSLGHGQHGS- 1471
                S S G S  Y +   R G+  RG      +GS   +  +  SG R   G G+ G  
Sbjct: 998  HDRSSNSYGRSDRYSRGRDRVGRPDRGLPLPMETGSPPLHDSYSRSGCRVPRGGGRQGGR 1057

Query: 1472 ---GSGQS 1476
               G G+S
Sbjct: 1058 FERGEGRS 1065



 Score =  169 bits (427), Expect = 5e-41
 Identities = 239/914 (26%), Positives = 333/914 (36%), Gaps = 160/914 (17%)

Query: 167  GQHNSYSGQSSSYGEQNSDSHQ----SSGRGQCGSGS--GQSPNYGQHGSGSGQSSSNDT 220
            G  N Y G+   Y +  S         S  G CG+    G  P+YG  G    +   N  
Sbjct: 279  GNQNGYRGRDHEYTDHPSKGSYREPLKSYGGPCGAAPVWGTPPSYGG-GCRYEEYQGNSP 337

Query: 221  HGSGSGQSS---------GFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGE 271
                 G+SS          +S+  S    S G S   +G   S  YG+ G         E
Sbjct: 338  DACSEGRSSEALPVVLPDAYSRDHSPKAYSGGRSSSSNGYSRSDRYGEEGCY-------E 390

Query: 272  RHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSY 331
             +R  S  + S G++ S +     H   G G  +      H + SG  S+       S  
Sbjct: 391  EYRGRSPDAHSGGRNSSSNSYGQSHHYGGEGRYEEYRGRSHEARSGGRSTDAHSRGRSDD 450

Query: 332  SYSRGHYESG-SGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQH 390
            +YS GH  S  S    G G++E   G+              S     G  S +A S G  
Sbjct: 451  AYSGGHDSSSWSDCCGGGGRYEEYQGR--------------SLDANSGGCSPEAYSGGHD 496

Query: 391  GSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSP-----GHGQRGSGSGQSPSSGQHGTG 445
             SS       G H   +R   G    ++  G+SP     GH    +  GQS   G  G  
Sbjct: 497  NSSWSDRYGVGGHYEENR---GHSLDANSGGRSPDTHSGGHSSSSNSYGQSHRYGGEGRY 553

Query: 446  FGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQH-GSRSGQSSRG 504
              R  S   +  G    +  G H+SSS+ +    ++G G  +    G+   + SG  S  
Sbjct: 554  EYRGRSHDAHSGGCSADAYSGGHDSSSQSN----RYGGGGCYEEYRGRSLDANSGGRSPN 609

Query: 505  ERQGSSAGSSSSYGQHGSGSR--QSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHG 562
               G    SS S+ ++G G R  +  G S   +  G+SP    G H+S S QS+ YG   
Sbjct: 610  AYSGGHDSSSWSH-RYGGGGRYEEYRGRSLDANSGGRSPDAYSGGHDS-SGQSNCYG--- 664

Query: 563  YGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSS 622
             G GR      YE   G              S G      S GH S              
Sbjct: 665  -GGGR------YEEYRG--------RLLDANSGGRSPDAYSGGHDS-------------- 695

Query: 623  CGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSG-QSPSRGRHGSDFGHSSSYGQHGSG 681
                   S QS+ +G  G G  +  R     + SG +SP     G D   SSS   H  G
Sbjct: 696  -------SSQSNRYG--GGGRYEEYRGHSLDANSGGRSPDTYSRGHD---SSSQSDHYGG 743

Query: 682  SGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSS--GYRKHGSRSGQSSRS 739
             G S      G +    SG GH S    SS   ++G G  +    G     +  G+S  +
Sbjct: 744  GGRSLDANSSGRLPDAYSG-GHDS----SSRSHRYGGGGRYEEYRGRSLDANSGGRSPNA 798

Query: 740  EQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSP---SRVRHGSSSGHSSSHGQHGS 796
               G +S   +   + G    ++ GH    +  GHSP   S  R  SS+ +  SH ++G 
Sbjct: 799  YSGGHNSSSRNDPCRGGGRYEENRGHSLDANSGGHSPNAYSGGRDSSSNSYDRSH-RYGG 857

Query: 797  GTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQ 856
            G       GHYE   G++     H++ S +G S    +  H++     G  S  S+S G+
Sbjct: 858  G-------GHYEEYRGRS-----HDTHS-RGRSPDAHSGDHYTEAYSRGRDS-FSNSYGR 903

Query: 857  HDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRS 916
             D   G+   Y +++  S +A G GR  + S  S G   R  G G+   Y        R 
Sbjct: 904  SD-HYGRGGCYEEYQGRSPNAYGGGRGLNSSNNSHGRSHRYGGGGRYEEY--------RG 954

Query: 917  SSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSS 976
             S   H  G         + SS +S G +    G GH   Y+  GS     S     G  
Sbjct: 955  PSPDAHSGG---------RDSSIKSYGLSDRYGGGGHYEEYQ--GSLPDAYS-----GDH 998

Query: 977  SGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS---GQSSSYGPYRSGSGW 1033
              SS+SYG+     R S G  + G      P P      +GS     S S    R   G 
Sbjct: 999  DRSSNSYGR---SDRYSRGRDRVGRPDRGLPLPME----TGSPPLHDSYSRSGCRVPRGG 1051

Query: 1034 SSSRGPYESGSGHS 1047
                G +E G G S
Sbjct: 1052 GRQGGRFERGEGRS 1065



 Score =  162 bits (410), Expect = 4e-39
 Identities = 284/1074 (26%), Positives = 377/1074 (35%), Gaps = 181/1074 (16%)

Query: 987  GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGH 1046
            GSGSR    H   G GS     PS+GR   G G +  +  +   +     RGP      H
Sbjct: 100  GSGSRSRFSHRTRGGGSSPQRPPSQGRPDDGRGYAGYFDLWPYRAPMPRKRGPPPR---H 156

Query: 1047 SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHG 1106
             +   H+ +            SS  HS   G  G     S   G  G    + +    H 
Sbjct: 157  WASPPHKRATP----------SSLAHSVGCGMRGKAPTVSGQDGYSGLQPRRWAGP-PHK 205

Query: 1107 SGSSQSSGYGRQGSGS-GQSPG-HGQRG-SGSR-QSPSYGRHGSGSGRSSSSGQHGSGLG 1162
                +SS     GSG  G++P   GQ G SG R + P       G    +         G
Sbjct: 206  RAVPRSSLARIGGSGMPGKAPAVWGQDGYSGPRVREPLPPCRDPGDFVPALRDYSRRYYG 265

Query: 1163 ESSGFGHHE-SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYG- 1220
             SS   +      G  + Y       G    Y  H S+       + +G   G++  +G 
Sbjct: 266  HSSVPDYRPLRGDGNQNGYR------GRDHEYTDHPSKGSYREPLKSYGGPCGAAPVWGT 319

Query: 1221 --QHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGL------GHSSSHGQHGSGSGRSSSRG 1272
               +G G R     G     S  + S GR    L       +S  H       GRSSS  
Sbjct: 320  PPSYGGGCRYEEYQGN----SPDACSEGRSSEALPVVLPDAYSRDHSPKAYSGGRSSSSN 375

Query: 1273 PYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQ 1332
             Y SRS             G    Y ++   S    S G++ S++           S GQ
Sbjct: 376  GY-SRSDRY----------GEEGCYEEYRGRSPDAHSGGRNSSSN-----------SYGQ 413

Query: 1333 SSSYGHRGSGSSQS--SGYGRHGAGSGQSPSRGRHG---SGSGHSSSYGQH-GSGSGWSS 1386
            S  YG  G        S   R G  S  + SRGR     SG   SSS+    G G  +  
Sbjct: 414  SHHYGGEGRYEEYRGRSHEARSGGRSTDAHSRGRSDDAYSGGHDSSSWSDCCGGGGRYEE 473

Query: 1387 SSGR----HGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHG--SRSGQSSRG 1440
              GR    +  G    +  G H++SSW      ++G G GH      H   + SG  S  
Sbjct: 474  YQGRSLDANSGGCSPEAYSGGHDNSSWSD----RYGVG-GHYEENRGHSLDANSGGRSPD 528

Query: 1441 ERHGSSSGSSSSYGQH----GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSP 1496
               G  S SS+SYGQ     G G  +  G        G S     G H S    SS  + 
Sbjct: 529  THSGGHSSSSNSYGQSHRYGGEGRYEYRGRSHDAHSGGCSADAYSGGHDS----SSQSNR 584

Query: 1497 YGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 1556
            YG G  +   RG   S  ++S G        G  S    H    G     G++    G+S
Sbjct: 585  YGGGGCYEEYRG--RSLDANSGGRSPNAYSGGHDSSSWSHRYGGG-----GRYEEYRGRS 637

Query: 1557 SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS 1616
                  G S    S  G H S S QS+ YG  G             SG R   +Y     
Sbjct: 638  LDANSGGRSPDAYS--GGHDS-SGQSNCYGGGGRYEEYRGRLLDANSGGRSPDAYS---G 691

Query: 1617 GSGRSSSSGQHGSG--LGESSGFGHHESSSGQS-SSYSQHGSGSGHSSGYGQHGSRSGQS 1673
            G   SS S ++G G    E  G     +S G+S  +YS+    S  S  YG  G     +
Sbjct: 692  GHDSSSQSNRYGGGGRYEEYRGHSLDANSGGRSPDTYSRGHDSSSQSDHYGGGGRSLDAN 751

Query: 1674 SRG---ERHGSSSRSSSRYGQHGSGSRQSSGHGRQ--GSGSGQSPSRGRHGSGLGHSSSH 1728
            S G   + +     SSSR  ++G G R     GR    +  G+SP+     SG  +SSS 
Sbjct: 752  SSGRLPDAYSGGHDSSSRSHRYGGGGRYEEYRGRSLDANSGGRSPNAY---SGGHNSSSR 808

Query: 1729 GQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHS-SAYSQHGSGSGHFCSQGQHGSTS 1787
                 G GR      YE   GHS       +  GHS +AYS     S +   +       
Sbjct: 809  NDPCRGGGR------YEENRGHSL----DANSGGHSPNAYSGGRDSSSNSYDRSHRYGGG 858

Query: 1788 GQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGS--GHSSSY 1845
            G    +        +  SH  H  G S  +  G   +   ++ SRGR    +  G S  Y
Sbjct: 859  GHYEEY--------RGRSHDTHSRGRSPDAHSGDHYT---EAYSRGRDSFSNSYGRSDHY 907

Query: 1846 GQ--------------HGSGSGWSSSSGRHGSGSGQSSGFGHHE--------------SS 1877
            G+              +G G G +SS+  HG  S +  G G +E               S
Sbjct: 908  GRGGCYEEYQGRSPNAYGGGRGLNSSNNSHGR-SHRYGGGGRYEEYRGPSPDAHSGGRDS 966

Query: 1878 SWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHG 1937
            S +S G +    G GH   Y+  GS     S     G    SS+SYG+     R S G  
Sbjct: 967  SIKSYGLSDRYGGGGHYEEYQ--GSLPDAYS-----GDHDRSSNSYGR---SDRYSRGRD 1016

Query: 1938 QHGSGSGQSPSP----SRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHS 1987
            + G      P P    S   H S S +S    P G G       G +E G G S
Sbjct: 1017 RVGRPDRGLPLPMETGSPPLHDSYS-RSGCRVPRGGG----RQGGRFERGEGRS 1065



 Score =  162 bits (410), Expect = 4e-39
 Identities = 260/1011 (25%), Positives = 339/1011 (33%), Gaps = 180/1011 (17%)

Query: 1927 GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGP------- 1979
            GSGSR    H   G GS     PS+GR   G G +  +  +   +     RGP       
Sbjct: 100  GSGSRSRFSHRTRGGGSSPQRPPSQGRPDDGRGYAGYFDLWPYRAPMPRKRGPPPRHWAS 159

Query: 1980 ------YESGSGHSSGLGHRESRSGQSSGYGQHG--------------------SSSGHS 2013
                    S   HS G G R      S   G  G                    +  G S
Sbjct: 160  PPHKRATPSSLAHSVGCGMRGKAPTVSGQDGYSGLQPRRWAGPPHKRAVPRSSLARIGGS 219

Query: 2014 STHGQHGSASGQSS-----------SCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS 2062
               G+  +  GQ              C   G        + +   G S    Y R   G 
Sbjct: 220  GMPGKAPAVWGQDGYSGPRVREPLPPCRDPGDFVPALRDYSRRYYGHSSVPDY-RPLRGD 278

Query: 2063 GQSPG----------HGQRGSGSRQSPSYG-------------RHGSGSGRSSSSGQHGP 2099
            G   G          H  +GS      SYG              +G G       G    
Sbjct: 279  GNQNGYRGRDHEYTDHPSKGSYREPLKSYGGPCGAAPVWGTPPSYGGGCRYEEYQGNSPD 338

Query: 2100 GLGES-----------SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHG------SRSGQ 2142
               E              +    S    S   S   +G   S  YG+ G       RS  
Sbjct: 339  ACSEGRSSEALPVVLPDAYSRDHSPKAYSGGRSSSSNGYSRSDRYGEEGCYEEYRGRSPD 398

Query: 2143 SSRGERHGSSS--GSSSRYGQHG--SGSRQSSGHGRQGSGSGHSPSRGRHG---SGSGHS 2195
            +  G R+ SS+  G S  YG  G     R  S   R G  S  + SRGR     SG   S
Sbjct: 399  AHSGGRNSSSNSYGQSHHYGGEGRYEEYRGRSHEARSGGRSTDAHSRGRSDDAYSGGHDS 458

Query: 2196 SSHGQHGSGSGRSSSRGPYESRSGHSSVFG---QHESGSGHSSAYSQHGSGSGHFCSQGQ 2252
            SS      G GR      Y+ RS  ++  G   +  SG   +S++S      GH+     
Sbjct: 459  SSWSDCCGGGGRYEE---YQGRSLDANSGGCSPEAYSGGHDNSSWSDRYGVGGHYEENRG 515

Query: 2253 HGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSG---- 2308
            H S    S     +  S G SSS   +G    QS  YG +G    +  S   H  G    
Sbjct: 516  H-SLDANSGGRSPDTHSGGHSSSSNSYG----QSHRYGGEGRYEYRGRSHDAHSGGCSAD 570

Query: 2309 ---SGH--SSSYGQHGSGSGWSSSSGR----HGSGSGQSSGFGHHESSSWQSSGYTQHGS 2359
                GH  SS   ++G G  +    GR    +  G   ++  G H+SSSW       H  
Sbjct: 571  AYSGGHDSSSQSNRYGGGGCYEEYRGRSLDANSGGRSPNAYSGGHDSSSW------SHRY 624

Query: 2360 GSGHSSSYEQHGSRSGQSSRGERHGSS-SGSSSSYGQ---HGSGSRQSLGHGQ--HGSGS 2413
            G G    YE++  RS  ++ G R   + SG   S GQ   +G G R     G+    +  
Sbjct: 625  GGG--GRYEEYRGRSLDANSGGRSPDAYSGGHDSSGQSNCYGGGGRYEEYRGRLLDANSG 682

Query: 2414 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGY 2473
            G+SP    G H S    SS  + YG G       G YE   GHS       +  G+S   
Sbjct: 683  GRSPDAYSGGHDS----SSQSNRYGGG-------GRYEEYRGHSLD----ANSGGRSPDT 727

Query: 2474 GQHGSSSGHSSTHGQHGSTSGQSSSCGQ-----HGASSGQSSSHGQHGSGS-SQSSGYGR 2527
               G  S   S H   G  S  ++S G+      G     S SH   G G   +  G   
Sbjct: 728  YSRGHDSSSQSDHYGGGGRSLDANSSGRLPDAYSGGHDSSSRSHRYGGGGRYEEYRGRSL 787

Query: 2528 QGSGSGQSPG--HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 2585
              +  G+SP    G   S SR  P  G       R  S   +  G   ++  G  +SSS 
Sbjct: 788  DANSGGRSPNAYSGGHNSSSRNDPCRGGGRYEENRGHSLDANSGGHSPNAYSGGRDSSSN 847

Query: 2586 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQ--SSGHG 2643
                  ++G G GH   Y   G      SRG    + SG   HY +  S  R   S+ +G
Sbjct: 848  SYDRSHRYG-GGGHYEEY--RGRSHDTHSRGRSPDAHSG--DHYTEAYSRGRDSFSNSYG 902

Query: 2644 RQ---GSGSGQSPSRGR----HGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQ 2696
            R    G G      +GR    +G G G +SS+  HG  S R    G YE   G S     
Sbjct: 903  RSDHYGRGGCYEEYQGRSPNAYGGGRGLNSSNNSHGR-SHRYGGGGRYEEYRGPSP--DA 959

Query: 2697 HESG---SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGS 2753
            H  G   S  S   S    G GH+  + Q       S   D+  +S G+S  Y      S
Sbjct: 960  HSGGRDSSIKSYGLSDRYGGGGHY-EEYQGSLPDAYSGDHDRSSNSYGRSDRY------S 1012

Query: 2754 SQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSG 2804
                  GR   G    +  G        S S  +   G G+  G  + G G
Sbjct: 1013 RGRDRVGRPDRGLPLPMETGSPPLHDSYSRSGCRVPRGGGRQGGRFERGEG 1063



 Score =  156 bits (395), Expect = 2e-37
 Identities = 277/1094 (25%), Positives = 367/1094 (33%), Gaps = 200/1094 (18%)

Query: 925  GSGQSSGFGHKSSSGQSS-------GYTQHGSG-SGHSSSYEQHGSRSGQSSRSEQHGSS 976
            GSG  S F H++  G SS       G    G G +G+   +        +     +H +S
Sbjct: 100  GSGSRSRFSHRTRGGGSSPQRPPSQGRPDDGRGYAGYFDLWPYRAPMPRKRGPPPRHWAS 159

Query: 977  SGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGP---------- 1026
                     H   +  SL H       G++P+ S     SG       GP          
Sbjct: 160  P-------PHKRATPSSLAHSVGCGMRGKAPTVSGQDGYSGLQPRRWAGPPHKRAVPRSS 212

Query: 1027 -YRSGSGWSSSRGPYESGSGHSSGLGHRE-------------SRSGQSSGYGQHGSSSGH 1072
              R G      + P   G    SG   RE             +    S  Y  H S   +
Sbjct: 213  LARIGGSGMPGKAPAVWGQDGYSGPRVREPLPPCRDPGDFVPALRDYSRRYYGHSSVPDY 272

Query: 1073 SSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHG--- 1129
                G            G      G+   +  H S  S        G   G +P  G   
Sbjct: 273  RPLRGD-----------GNQNGYRGRDHEYTDHPSKGSYREPLKSYGGPCGAAPVWGTPP 321

Query: 1130 QRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGE--SSGFGHHESSSGQSSSYSQHGSGS 1187
              G G R    Y  +   S  + S G+    L       +    S    S   S   +G 
Sbjct: 322  SYGGGCR----YEEYQGNSPDACSEGRSSEALPVVLPDAYSRDHSPKAYSGGRSSSSNGY 377

Query: 1188 GHSSGYGQHG------SRSGQSSRGERHGSSS--GSSSHYGQHGSGS--RQSSGHGRQGS 1237
              S  YG+ G       RS  +  G R+ SS+  G S HYG  G     R  S   R G 
Sbjct: 378  SRSDRYGEEGCYEEYRGRSPDAHSGGRNSSSNSYGQSHHYGGEGRYEEYRGRSHEARSGG 437

Query: 1238 GSGHSPSRGRHGSGL--GHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 1295
             S  + SRGR       GH SS      G G     G YE   G S       SG     
Sbjct: 438  RSTDAHSRGRSDDAYSGGHDSSSWSDCCGGG-----GRYEEYQGRSL---DANSGGCSPE 489

Query: 1296 AYS---QHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYG-- 1350
            AYS    + S S  +   G +    G S       +++G  S   H G  SS S+ YG  
Sbjct: 490  AYSGGHDNSSWSDRYGVGGHYEENRGHSLD-----ANSGGRSPDTHSGGHSSSSNSYGQS 544

Query: 1351 -RHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSW 1409
             R+G G G+   RGR         S+  H  G    + SG H S S         +S+ +
Sbjct: 545  HRYG-GEGRYEYRGR---------SHDAHSGGCSADAYSGGHDSSS---------QSNRY 585

Query: 1410 QSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGER--HGSSSGSSSSYGQH--GSGSR--QS 1463
               GC            YE++  RS  ++ G R  +  S G  SS   H  G G R  + 
Sbjct: 586  GGGGC------------YEEYRGRSLDANSGGRSPNAYSGGHDSSSWSHRYGGGGRYEEY 633

Query: 1464 LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRG---PYESGSSHSSGL 1520
             G     +  G+SP    G H S SGQS+    YG G  +   RG      SG       
Sbjct: 634  RGRSLDANSGGRSPDAYSGGHDS-SGQSNC---YGGGGRYEEYRGRLLDANSGGRSPDAY 689

Query: 1521 GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS 1580
                  S QS+ YG  G    +   H    ++ G+S      G  S   S H   G  S 
Sbjct: 690  SGGHDSSSQSNRYGGGGRYEEYRG-HSLDANSGGRSPDTYSRGHDSSSQSDHYGGGGRSL 748

Query: 1581 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 1640
             ++  GR       S GH    S S +    GR+    GRS  +   G      SG GH+
Sbjct: 749  DANSSGR--LPDAYSGGH-DSSSRSHRYGGGGRYEEYRGRSLDANSGGRSPNAYSG-GHN 804

Query: 1641 ESS-SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQS 1699
             SS +       ++    GHS      G      S G    SSS S  R  ++G G    
Sbjct: 805  SSSRNDPCRGGGRYEENRGHSLDANSGGHSPNAYSGG--RDSSSNSYDRSHRYGGGGHYE 862

Query: 1700 SGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHES 1759
               GR    S  + SRGR  S   HS  H       GR S    Y  RS H    G +E 
Sbjct: 863  EYRGR----SHDTHSRGR--SPDAHSGDHYTEAYSRGRDSFSNSY-GRSDHYGRGGCYEE 915

Query: 1760 GSGHSSAYSQHGSGSGHFCSQGQHGSTS--GQSSTFDQEGSSTGQSSSHGQHGSGSSQSS 1817
              G S   + +G G G   S   HG +   G    +++    +  + S G+     S   
Sbjct: 916  YQGRSP--NAYGGGRGLNSSNNSHGRSHRYGGGGRYEEYRGPSPDAHSGGR----DSSIK 969

Query: 1818 SYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESS 1877
            SYG             R+G G GH   Y                  GS   +  G H+ S
Sbjct: 970  SYGLS----------DRYG-GGGHYEEY-----------------QGSLPDAYSGDHDRS 1001

Query: 1878 SWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHG-SGSRQSLGH 1936
            S          +  G S  Y +   R G+  RG      +GS   +  +  SG R   G 
Sbjct: 1002 S----------NSYGRSDRYSRGRDRVGRPDRGLPLPMETGSPPLHDSYSRSGCRVPRGG 1051

Query: 1937 GQHGS----GSGQS 1946
            G+ G     G G+S
Sbjct: 1052 GRQGGRFERGEGRS 1065



 Score =  149 bits (377), Expect = 3e-35
 Identities = 238/902 (26%), Positives = 313/902 (34%), Gaps = 160/902 (17%)

Query: 1560 GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHG---QRGSGSRQSPSYGRHGS 1616
            G      G+   +  H S  S        G   G +P  G     G G R    Y  +  
Sbjct: 279  GNQNGYRGRDHEYTDHPSKGSYREPLKSYGGPCGAAPVWGTPPSYGGGCR----YEEYQG 334

Query: 1617 GSGRSSSSGQHGSGLGE--SSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHG------S 1668
             S  + S G+    L       +    S    S   S   +G   S  YG+ G       
Sbjct: 335  NSPDACSEGRSSEALPVVLPDAYSRDHSPKAYSGGRSSSSNGYSRSDRYGEEGCYEEYRG 394

Query: 1669 RSGQSSRGERHGSSSRSSSRYGQHGSGS----RQSSGHGRQGSGSGQSPSRGRHGSGL-- 1722
            RS  +  G R+ SS+     +   G G     R  S   R G  S  + SRGR       
Sbjct: 395  RSPDAHSGGRNSSSNSYGQSHHYGGEGRYEEYRGRSHEARSGGRSTDAHSRGRSDDAYSG 454

Query: 1723 GHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYS---QHGSGSGHFCS 1779
            GH SS      G G     G YE   G S       SG     AYS    + S S  +  
Sbjct: 455  GHDSSSWSDCCGGG-----GRYEEYQGRSL---DANSGGCSPEAYSGGHDNSSWSDRYGV 506

Query: 1780 QGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQG--SGSGQSPSRGRHGS 1837
             G +    G S   +  G S    S     G  SS S+SYGQ     G G+   RGR   
Sbjct: 507  GGHYEENRGHSLDANSGGRSPDTHS-----GGHSSSSNSYGQSHRYGGEGRYEYRGR--- 558

Query: 1838 GSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSY 1897
                  S+  H  G    + SG H S S              QS+ Y       G    Y
Sbjct: 559  ------SHDAHSGGCSADAYSGGHDSSS--------------QSNRY-------GGGGCY 591

Query: 1898 EQHGSRS-GQSSRGEQHGSSSG---SSSSYGQHGSGSR--QSLGHGQHGSGSGQSPSPSR 1951
            E++  RS   +S G    + SG   SSS   ++G G R  +  G     +  G+SP    
Sbjct: 592  EEYRGRSLDANSGGRSPNAYSGGHDSSSWSHRYGGGGRYEEYRGRSLDANSGGRSPDAYS 651

Query: 1952 GRHGSGSGQSSSYGPYGSGSGW--------SSSRGPYESGSGHSSGLGHRESRSGQSSGY 2003
            G H S SGQS+ YG  G    +        S  R P     GH S      S+S +  G 
Sbjct: 652  GGHDS-SGQSNCYGGGGRYEEYRGRLLDANSGGRSPDAYSGGHDS-----SSQSNRYGGG 705

Query: 2004 GQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSG 2063
            G++    GHS       ++ G+S      G  S   S H   G  S  ++  GR      
Sbjct: 706  GRYEEYRGHS----LDANSGGRSPDTYSRGHDSSSQSDHYGGGGRSLDANSSGR--LPDA 759

Query: 2064 QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESS-SGQSSSYSQ 2122
             S GH    S S +    GR+    GRS  +   G      SG GH+ SS +       +
Sbjct: 760  YSGGH-DSSSRSHRYGGGGRYEEYRGRSLDANSGGRSPNAYSG-GHNSSSRNDPCRGGGR 817

Query: 2123 HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGH- 2181
            +    GHS      G      S G    SSS S  R  ++G G     GH  +  G  H 
Sbjct: 818  YEENRGHSLDANSGGHSPNAYSGG--RDSSSNSYDRSHRYGGG-----GHYEEYRGRSHD 870

Query: 2182 SPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHG 2241
            + SRGR  S   HS  H       GR S    Y  RS H    G +E   G S   + +G
Sbjct: 871  THSRGR--SPDAHSGDHYTEAYSRGRDSFSNSY-GRSDHYGRGGCYEEYQGRSP--NAYG 925

Query: 2242 SGSGHFCSQGQHGSTS--GQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQS 2299
             G G   S   HG +   G    +++    +  + S G+     S   SYG         
Sbjct: 926  GGRGLNSSNNSHGRSHRYGGGGRYEEYRGPSPDAHSGGR----DSSIKSYGLS------- 974

Query: 2300 PSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGS 2359
                R+G G GH   Y                  GS   +  G H+ SS          +
Sbjct: 975  ---DRYG-GGGHYEEY-----------------QGSLPDAYSGDHDRSS----------N 1003

Query: 2360 GSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHG-SGSRQSLGHGQHGS----GSG 2414
              G S  Y +   R G+  RG      +GS   +  +  SG R   G G+ G     G G
Sbjct: 1004 SYGRSDRYSRGRDRVGRPDRGLPLPMETGSPPLHDSYSRSGCRVPRGGGRQGGRFERGEG 1063

Query: 2415 QS 2416
            +S
Sbjct: 1064 RS 1065



 Score =  149 bits (375), Expect = 5e-35
 Identities = 201/777 (25%), Positives = 271/777 (34%), Gaps = 106/777 (13%)

Query: 160  SFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGS-GSGQSSSN 218
            ++ RD S +  S    SSS G   SD                   YG+ G     +  S 
Sbjct: 356  AYSRDHSPKAYSGGRSSSSNGYSRSD------------------RYGEEGCYEEYRGRSP 397

Query: 219  DTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGY--GQHGSRSGQSSRGERHRSS 276
            D H  G          ++SS  S G S H  G G    Y    H +RSG  S     R  
Sbjct: 398  DAHSGG----------RNSSSNSYGQSHHYGGEGRYEEYRGRSHEARSGGRSTDAHSRGR 447

Query: 277  SGSSSSYGQH--------GSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSG 328
            S  + S G          G G R     GR    +    S   +  G  +SS   ++G G
Sbjct: 448  SDDAYSGGHDSSSWSDCCGGGGRYEEYQGRSLDANSGGCSPEAYSGGHDNSSWSDRYGVG 507

Query: 329  SSYSYSRGH---YESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQ-HGSTSGQA 384
              Y  +RGH     SG           S S  S G S    G G    +G+ H + SG  
Sbjct: 508  GHYEENRGHSLDANSGGRSPDTHSGGHSSSSNSYGQSHRYGGEGRYEYRGRSHDAHSGGC 567

Query: 385  SS---SGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQ 441
            S+   SG H SSS QS+ YG       +  GR   ++  G+SP         G   SS  
Sbjct: 568  SADAYSGGHDSSS-QSNRYGGGGCYEEY-RGRSLDANSGGRSP----NAYSGGHDSSSWS 621

Query: 442  HGTGFG------RSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHG 495
            H  G G      R  S      G    +  G H+SS + +     +G G  +    G+  
Sbjct: 622  HRYGGGGRYEEYRGRSLDANSGGRSPDAYSGGHDSSGQSNC----YGGGGRYEEYRGRLL 677

Query: 496  SRSGQSSRGERQGSSAGSSSSYGQHGSGSR--QSLGHSRHGSGSGQSPSPSRGRHESGSR 553
              +      +       SSS   ++G G R  +  GHS   +  G+SP      H+S S 
Sbjct: 678  DANSGGRSPDAYSGGHDSSSQSNRYGGGGRYEEYRGHSLDANSGGRSPDTYSRGHDSSS- 736

Query: 554  QSSSYGPHGYG-SGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQ 612
            QS  YG  G      SS R P     GH S      SRS +  G G++    G S     
Sbjct: 737  QSDHYGGGGRSLDANSSGRLPDAYSGGHDS-----SSRSHRYGGGGRYEEYRGRSLDANS 791

Query: 613  HGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSP---SRGRHGSDF 669
             G +    S  G H ++S      G  G    ++  +    +  G SP   S GR  S  
Sbjct: 792  GGRSPNAYS--GGHNSSSRNDPCRG--GGRYEENRGHSLDANSGGHSPNAYSGGRDSSSN 847

Query: 670  GHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKH 729
             +  S+ ++G G  +    G       +       SG   +  YS+     S+S G   H
Sbjct: 848  SYDRSH-RYGGGGHYEEYRGRSHDTHSRGRSPDAHSGDHYTEAYSRGRDSFSNSYGRSDH 906

Query: 730  GSRSG-----QSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSS 784
              R G     Q      +G   GL+SS   HG  SH+  G GR     G SP       S
Sbjct: 907  YGRGGCYEEYQGRSPNAYGGGRGLNSSNNSHGR-SHRYGGGGRYEEYRGPSPD----AHS 961

Query: 785  SGHSSSHGQHGSGTSCSSSCGHYE--SGSGQASGFGQHESGSGQGYSQHGSASGHFSSQG 842
             G  SS   +G         GHYE   GS   +  G H+  S              +S G
Sbjct: 962  GGRDSSIKSYGLSDRYGGG-GHYEEYQGSLPDAYSGDHDRSS--------------NSYG 1006

Query: 843  RHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSG 899
            R    S      G+ D         G       ++    R   G G+  G  +RG G
Sbjct: 1007 RSDRYSRGRDRVGRPDRGLPLPMETGSPPLHDSYSRSGCRVPRGGGRQGGRFERGEG 1063



 Score =  143 bits (360), Expect = 3e-33
 Identities = 247/1015 (24%), Positives = 322/1015 (31%), Gaps = 199/1015 (19%)

Query: 287  GSGSRQSLGHGRQGSGS--RQSPSHVRHGSGSGH------------------------SS 320
            GSGSR    H  +G GS  ++ PS  R   G G+                        +S
Sbjct: 100  GSGSRSRFSHRTRGGGSSPQRPPSQGRPDDGRGYAGYFDLWPYRAPMPRKRGPPPRHWAS 159

Query: 321  SHGQHGSGSSYSYS-----RGHYESGSGQTSGFG-QHESGSGQSSGYSKHGSGSGHSSSQ 374
               +  + SS ++S     RG   + SGQ    G Q    +G     +   S        
Sbjct: 160  PPHKRATPSSLAHSVGCGMRGKAPTVSGQDGYSGLQPRRWAGPPHKRAVPRSSLARIGGS 219

Query: 375  GQHGSTSGQASSSGQHGSSSRQ----SSSYGQHESASRHSSGRGQ-HSS--------GSG 421
            G  G         G  G   R+        G    A R  S R   HSS        G G
Sbjct: 220  GMPGKAPAVWGQDGYSGPRVREPLPPCRDPGDFVPALRDYSRRYYGHSSVPDYRPLRGDG 279

Query: 422  QSPGHGQRGSGSGQSPSSGQH-------------------------GTGFGRSSSSGPYV 456
               G+  R       PS G +                         G  +     + P  
Sbjct: 280  NQNGYRGRDHEYTDHPSKGSYREPLKSYGGPCGAAPVWGTPPSYGGGCRYEEYQGNSPDA 339

Query: 457  SGSGYSS---------GFGHHESSSEHSSGYTQHGSGSGHSSGHGQHG------SRSGQS 501
               G SS          +    S   +S G +   +G   S  +G+ G       RS  +
Sbjct: 340  CSEGRSSEALPVVLPDAYSRDHSPKAYSGGRSSSSNGYSRSDRYGEEGCYEEYRGRSPDA 399

Query: 502  SRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSG--QSPSPSRGRHE---SGSRQSS 556
              G R  SS     S+   G G  +      H + SG   + + SRGR +   SG   SS
Sbjct: 400  HSGGRNSSSNSYGQSHHYGGEGRYEEYRGRSHEARSGGRSTDAHSRGRSDDAYSGGHDSS 459

Query: 557  SYGPHGYGSGR------------SSSRGPYESGSGHSSGL--------GHQESRSGQSSG 596
            S+     G GR            S    P     GH +          GH E   G S  
Sbjct: 460  SWSDCCGGGGRYEEYQGRSLDANSGGCSPEAYSGGHDNSSWSDRYGVGGHYEENRGHSLD 519

Query: 597  YGQHG-SSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSG------------S 643
                G S   HS  H    ++ GQS   G  G    +  SH  H  G            S
Sbjct: 520  ANSGGRSPDTHSGGHSSSSNSYGQSHRYGGEGRYEYRGRSHDAHSGGCSADAYSGGHDSS 579

Query: 644  SQSSRYGQQG--------SGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVS 695
            SQS+RYG  G        S    S  R  +    GH SS   H  G G         S+ 
Sbjct: 580  SQSNRYGGGGCYEEYRGRSLDANSGGRSPNAYSGGHDSSSWSHRYGGGGRYEEYRGRSLD 639

Query: 696  GQSSGFGHK--SGSGQSSGYSQHGSGSSHSSGYRKH--GSRSGQSSRSEQHGSSSGLSSS 751
              S G      SG   SSG S    G      YR     + SG  S     G     S S
Sbjct: 640  ANSGGRSPDAYSGGHDSSGQSNCYGGGGRYEEYRGRLLDANSGGRSPDAYSGGHDSSSQS 699

Query: 752  YGQHGSGSHQS-SGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYES- 809
                G G ++   GH    +  G SP     G  S   S H   G  +  ++S G     
Sbjct: 700  NRYGGGGRYEEYRGHSLDANSGGRSPDTYSRGHDSSSQSDHYGGGGRSLDANSSGRLPDA 759

Query: 810  -GSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYG 868
               G  S    H  G G  Y ++   S   +S GR       ++ SG H+SSS      G
Sbjct: 760  YSGGHDSSSRSHRYGGGGRYEEYRGRSLDANSGGR-----SPNAYSGGHNSSSRNDPCRG 814

Query: 869  QHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQ 928
                           G    ++ GH    +  G SP    +    GR SSS  +      
Sbjct: 815  ---------------GGRYEENRGHSLDANSGGHSP----NAYSGGRDSSSNSYDRSHRY 855

Query: 929  SSGFGHKSSSGQSSGYTQHG-SGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHG 987
              G  ++   G+S      G S   HS  +       G+ S S    +S G S  YG+ G
Sbjct: 856  GGGGHYEEYRGRSHDTHSRGRSPDAHSGDHYTEAYSRGRDSFS----NSYGRSDHYGR-G 910

Query: 988  SGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHS 1047
                +  G   +  G G+  + S   H    G+S  YG    G  +   RGP  S   HS
Sbjct: 911  GCYEEYQGRSPNAYGGGRGLNSSNNSH----GRSHRYG---GGGRYEEYRGP--SPDAHS 961

Query: 1048 SGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGS 1107
             G        G S  YG  G        H +    S   +  G H  S   S+S+G+   
Sbjct: 962  GGRDSSIKSYGLSDRYGGGG--------HYEEYQGSLPDAYSGDHDRS---SNSYGRSDR 1010

Query: 1108 GSSQSSGYGRQGSG------SGQSPGHGQRG-SGSRQSPSYGRHGS----GSGRS 1151
             S      GR   G      +G  P H     SG R     GR G     G GRS
Sbjct: 1011 YSRGRDRVGRPDRGLPLPMETGSPPLHDSYSRSGCRVPRGGGRQGGRFERGEGRS 1065



 Score =  112 bits (281), Expect = 4e-24
 Identities = 176/710 (24%), Positives = 251/710 (35%), Gaps = 99/710 (13%)

Query: 102  RDDTHQHQEEQEETEKEENKRQESSFS----HSSWS-----AGENDSYSRNV----RGSL 148
            R  +H+ +     T+     R + ++S     SSWS      G  + Y         G  
Sbjct: 427  RGRSHEARSGGRSTDAHSRGRSDDAYSGGHDSSSWSDCCGGGGRYEEYQGRSLDANSGGC 486

Query: 149  KPGTESISRRLSFQRD---FSGQHNSYSGQS--SSYGEQNSDSHQSSGRGQCGSGSGQSP 203
             P   S     S   D     G +    G S  ++ G ++ D+H S G     +  GQS 
Sbjct: 487  SPEAYSGGHDNSSWSDRYGVGGHYEENRGHSLDANSGGRSPDTH-SGGHSSSSNSYGQSH 545

Query: 204  NYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSR 263
             YG  G    +  S+D H SG   +  +S    SS QS+ Y   G        Y ++  R
Sbjct: 546  RYGGEGRYEYRGRSHDAH-SGGCSADAYSGGHDSSSQSNRYGGGGC-------YEEYRGR 597

Query: 264  SGQSSRGERHRS--SSGSSSSYGQH--GSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHS 319
            S  ++ G R  +  S G  SS   H  G G R     GR    +    S   +  G   S
Sbjct: 598  SLDANSGGRSPNAYSGGHDSSSWSHRYGGGGRYEEYRGRSLDANSGGRSPDAYSGGHDSS 657

Query: 320  SSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGS 379
                 +G G  Y   RG     +        +  G   SS  +++G G  +   +G    
Sbjct: 658  GQSNCYGGGGRYEEYRGRLLDANSGGRSPDAYSGGHDSSSQSNRYGGGGRYEEYRGH--- 714

Query: 380  TSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSS 439
             S  A+S G      R   +Y    S    SS +  H  G G+S       + SG+ P +
Sbjct: 715  -SLDANSGG------RSPDTY----SRGHDSSSQSDHYGGGGRS----LDANSSGRLPDA 759

Query: 440  GQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSG 499
              +  G   SS S  Y  G  Y    G   S   +S G + +    GH+S       R G
Sbjct: 760  --YSGGHDSSSRSHRYGGGGRYEEYRG--RSLDANSGGRSPNAYSGGHNSSSRNDPCRGG 815

Query: 500  ---QSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSR-HGSGSGQSPSPSRGR-HESGSRQ 554
               + +RG    +++G  S     G     S  + R H  G G      RGR H++ SR 
Sbjct: 816  GRYEENRGHSLDANSGGHSPNAYSGGRDSSSNSYDRSHRYGGGGHYEEYRGRSHDTHSR- 874

Query: 555  SSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHG 614
                       GRS      ++ SG      +   R   S+ YG+    S H    G + 
Sbjct: 875  -----------GRSP-----DAHSGDHYTEAYSRGRDSFSNSYGR----SDHYGRGGCYE 914

Query: 615  STSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQG---SGSGQSPSRGRHGSDFGH 671
               G+S +   +G   G +SS+  HG    +S RYG  G      G SP     G D   
Sbjct: 915  EYQGRSPNA--YGGGRGLNSSNNSHG----RSHRYGGGGRYEEYRGPSPDAHSGGRD-SS 967

Query: 672  SSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGS 731
              SYG      G        GS+    SG   +S        + +G    +S G R    
Sbjct: 968  IKSYGLSDRYGGGGHYEEYQGSLPDAYSGDHDRSS-------NSYGRSDRYSRG-RDRVG 1019

Query: 732  RSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRH 781
            R  +         S  L  SY +  SG     G GRQG        R R+
Sbjct: 1020 RPDRGLPLPMETGSPPLHDSYSR--SGCRVPRGGGRQGGRFERGEGRSRY 1067



 Score = 97.8 bits (242), Expect = 1e-19
 Identities = 166/713 (23%), Positives = 233/713 (32%), Gaps = 118/713 (16%)

Query: 2163 GSGSRQSSGHGRQGSGSG--HSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGH 2220
            GSGSR    H  +G GS     PS+GR   G G++         +     RGP       
Sbjct: 100  GSGSRSRFSHRTRGGGSSPQRPPSQGRPDDGRGYAGYFDLWPYRAPMPRKRGPPP----- 154

Query: 2221 SSVFGQHESGSGHSSAYSQ---HGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHG 2277
                 +H +   H  A      H  G G    +G+  + SGQ    D       +  +  
Sbjct: 155  -----RHWASPPHKRATPSSLAHSVGCG---MRGKAPTVSGQ----DGYSGLQPRRWAGP 202

Query: 2278 QHGSGSSQSSSYGQQGSGS-GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 2336
             H     +SS     GSG  G++P+             +GQ     G+S    R      
Sbjct: 203  PHKRAVPRSSLARIGGSGMPGKAPA------------VWGQ----DGYSGPRVREPLPPC 246

Query: 2337 QSSG-------------FGHHESSSWQS-SGYTQHGSGSGHSSSYEQHGSRSGQSSRGER 2382
            +  G             +GH     ++   G        G    Y  H S+       + 
Sbjct: 247  RDPGDFVPALRDYSRRYYGHSSVPDYRPLRGDGNQNGYRGRDHEYTDHPSKGSYREPLKS 306

Query: 2383 HGSSSGSSSSYG---QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGS 2439
            +G   G++  +G    +G G R       +    G SP           G+SS   P   
Sbjct: 307  YGGPCGAAPVWGTPPSYGGGCR-------YEEYQGNSPD------ACSEGRSSEALPVVL 353

Query: 2440 GSGWSSSRGP--YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTS--GQ 2495
               +S    P  Y  G   SS    R  R G+   Y ++   S  + + G++ S++  GQ
Sbjct: 354  PDAYSRDHSPKAYSGGRSSSSNGYSRSDRYGEEGCYEEYRGRSPDAHSGGRNSSSNSYGQ 413

Query: 2496 SSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQR------GSGSRQSP 2549
            S   G  G          +  SG   +  + R  S    S GH         G G R   
Sbjct: 414  SHHYGGEGRYEEYRGRSHEARSGGRSTDAHSRGRSDDAYSGGHDSSSWSDCCGGGGRYEE 473

Query: 2550 SYGRH-----GSGSGRSSSSGQHGSGLGESSGFG-HHESSSGQSSSYSQHG-SGSGHSSG 2602
              GR      G  S  + S G   S   +  G G H+E + G S   +  G S   HS G
Sbjct: 474  YQGRSLDANSGGCSPEAYSGGHDNSSWSDRYGVGGHYEENRGHSLDANSGGRSPDTHSGG 533

Query: 2603 YGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL 2662
            +    +  GQS R             YG  G    +   H     G       G H S  
Sbjct: 534  HSSSSNSYGQSHR-------------YGGEGRYEYRGRSHDAHSGGCSADAYSGGHDS-- 578

Query: 2663 GHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ 2722
              SS   ++G G      RG   S   +S     +    GH S+   H  G G     G+
Sbjct: 579  --SSQSNRYGGGGCYEEYRG--RSLDANSGGRSPNAYSGGHDSSSWSHRYGGG-----GR 629

Query: 2723 HGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQS-SGYGRHGAGSGQSLSHGRHG----- 2776
            +    G+S   +  G S    S  GH  SG S    G GR+    G+ L     G     
Sbjct: 630  YEEYRGRSLDANSGGRSPDAYSG-GHDSSGQSNCYGGGGRYEEYRGRLLDANSGGRSPDA 688

Query: 2777 -SGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGSYF 2828
             SG   SSS      G G+   Y  H   +   G S       HD  S   ++
Sbjct: 689  YSGGHDSSSQSNRYGGGGRYEEYRGHSLDANSGGRSPDTYSRGHDSSSQSDHY 741



 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 156/639 (24%), Positives = 223/639 (34%), Gaps = 114/639 (17%)

Query: 2280 GSGSSQSSSYGQQGSGSG--QSPSRGRHGSGSGHSSSYG-----------QHGSGSGWSS 2326
            GSGS    S+  +G GS   + PS+GR   G G++  +            +      W+S
Sbjct: 100  GSGSRSRFSHRTRGGGSSPQRPPSQGRPDDGRGYAGYFDLWPYRAPMPRKRGPPPRHWAS 159

Query: 2327 --------SSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHG-SRSGQS 2377
                    SS  H  G G              S    +  +G  H  +  +   +R G S
Sbjct: 160  PPHKRATPSSLAHSVGCGMRGKAPTVSGQDGYSGLQPRRWAGPPHKRAVPRSSLARIGGS 219

Query: 2378 SRGERHGSSSGSSSSYGQHG-SGSR------------------QSLGHGQHGSGSGQSPS 2418
                  G    + + +GQ G SG R                  +      +G  S     
Sbjct: 220  ------GMPGKAPAVWGQDGYSGPRVREPLPPCRDPGDFVPALRDYSRRYYGHSSVPDYR 273

Query: 2419 PSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYES-----------GSGHSSGLGHR-ESR 2466
            P RG  G+ +G       Y       S R P +S           G+  S G G R E  
Sbjct: 274  PLRG-DGNQNGYRGRDHEYTDHPSKGSYREPLKSYGGPCGAAPVWGTPPSYGGGCRYEEY 332

Query: 2467 SGQSSGYGQHGSSS---------GHSSTHGQHGSTSGQSSSCGQHGASS--GQSSSHGQH 2515
             G S      G SS          +S  H     + G+SSS   +  S   G+   + ++
Sbjct: 333  QGNSPDACSEGRSSEALPVVLPDAYSRDHSPKAYSGGRSSSSNGYSRSDRYGEEGCYEEY 392

Query: 2516 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESS 2575
               S  +   GR  S +     H   G G  +      H + SG  S+   H  G  + +
Sbjct: 393  RGRSPDAHSGGRNSSSNSYGQSHHYGGEGRYEEYRGRSHEARSGGRSTDA-HSRGRSDDA 451

Query: 2576 GFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG----ERHGSSSGSSSHYGQ 2631
              G H+SSS     +S    G G    Y ++  RS  ++ G    E +     +SS   +
Sbjct: 452  YSGGHDSSS-----WSDCCGGGGR---YEEYQGRSLDANSGGCSPEAYSGGHDNSSWSDR 503

Query: 2632 HGSGSR--QSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLG 2689
            +G G    ++ GH    +  G+SP      SG GHSSS   +G  S R    G YE R G
Sbjct: 504  YGVGGHYEENRGHSLDANSGGRSPDTH---SG-GHSSSSNSYGQ-SHRYGGEGRYEYR-G 557

Query: 2690 HSSVFGQHESGSGHSSAYSQHG-----SGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS 2744
             S     H++ SG  SA +  G     S S  +   G +    G+S   +  G S    S
Sbjct: 558  RS-----HDAHSGGCSADAYSGGHDSSSQSNRYGGGGCYEEYRGRSLDANSGGRSPNAYS 612

Query: 2745 SYGHRGSGSSQSSGYGRHGAGSGQSLSHGRH---GSGSGQSSSYGQHGSGSGQSSGYSQH 2801
                   G   SS   R+G G       GR     SG     +Y      SGQS+ Y   
Sbjct: 613  G------GHDSSSWSHRYGGGGRYEEYRGRSLDANSGGRSPDAYSGGHDSSGQSNCY--- 663

Query: 2802 GSGSGQDGYSYCKGGSNHDGGSSGSYFLSFPSSTSPYEY 2840
            G G   + Y      +N  G S  +Y     SS+    Y
Sbjct: 664  GGGGRYEEYRGRLLDANSGGRSPDAYSGGHDSSSQSNRY 702


>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
            [Homo sapiens]
          Length = 526

 Score =  139 bits (350), Expect = 4e-32
 Identities = 150/509 (29%), Positives = 193/509 (37%), Gaps = 52/509 (10%)

Query: 1015 GSGSGQSSSYGPY--RSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGH 1072
            G G  Q SS  PY  +S SG+S S     SG G SS   + +S   Q++GYG   +  G+
Sbjct: 22   GQGYSQQSSQ-PYGQQSYSGYSQSTDT--SGYGQSSYSSYGQS---QNTGYGTQSTPQGY 75

Query: 1073 SSTHGQHGSTS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS-GQSP 1126
             ST G   S S     GQ SS   +G     SS+ G +GS SSQSS YG+  SGS  Q P
Sbjct: 76   GSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS-SSQSSSYGQPQSGSYSQQP 134

Query: 1127 GHG--QRGSGSRQS--PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSS--- 1179
             +G  Q+  G +QS  P  G        SSS G  G G G + G      SSG  S    
Sbjct: 135  SYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGY 194

Query: 1180 YSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS 1239
             +Q  SG G S GYGQ   R G+   G   G   G   +    G    +  G GR G G 
Sbjct: 195  GNQDQSGGGGSGGYGQQ-DRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGG 253

Query: 1240 GHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF---GQHESGSGHSSA 1296
                 RG      G      +H S    S +   +    G +        +    G    
Sbjct: 254  MGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKT 313

Query: 1297 YSQHGSGSGHFCSQGQHGSTSGQSS-TFDQEGSSTGQSSSY-GHRGSGSSQSSGYGRHGA 1354
              + G    +  +  + G   G+++ +FD   S+      + G   SG+     +    A
Sbjct: 314  NKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRA 373

Query: 1355 GSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQ---- 1410
               +    GR G G G     G+ G G G S   GR G  SG   G G   +  W+    
Sbjct: 374  DFNRGGGNGRGGRGRG--GPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNP 431

Query: 1411 ---------SSGCTQ------HGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQ 1455
                      + C Q       G G G   S+   G   G   RG R G   G     G 
Sbjct: 432  TCENMNFSWRNECNQCKAPKPDGPGGGPGGSH--MGGNYGDDRRGGRGGYDRGGYRGRGG 489

Query: 1456 HGSGSRQSLGHGQHGSGSGQSPSPSRGRH 1484
               G R   G G  G G G     SRG H
Sbjct: 490  DRGGFRGGRGGGDRG-GFGPGKMDSRGEH 517



 Score =  136 bits (343), Expect = 3e-31
 Identities = 150/540 (27%), Positives = 214/540 (39%), Gaps = 75/540 (13%)

Query: 2169 SSGHGRQGSGS-GHSPSRGRHGSGSGHSSSHGQHG-SGSGRSSSRGPYESRSGHSSVFGQ 2226
            S+ + +Q + S G  P++   G     S  +GQ   SG  +S+    Y  +S +SS    
Sbjct: 3    SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGY-GQSSYSSYGQS 61

Query: 2227 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQS 2286
              +G G  S    +GS  G+  SQ    S+ GQ S++   G     SS+ G +GS SSQS
Sbjct: 62   QNTGYGTQSTPQGYGSTGGYGSSQSSQ-SSYGQQSSYPGYGQQPAPSSTSGSYGS-SSQS 119

Query: 2287 SSYGQQGSGS-GQSPSRGRHGSGSGHSSSYGQ---HGSGSGWSSSSGRHGSGSGQSSGFG 2342
            SSYGQ  SGS  Q PS G      G   SY     +G  + ++SSSG  G G G    +G
Sbjct: 120  SSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSG-GGGGGGGGGNYG 178

Query: 2343 HHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSG--S 2400
              +SS   SSG    GSG G+ +  +  G  SG   + +R G   G S   G  G G  +
Sbjct: 179  QDQSS--MSSG---GGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYN 233

Query: 2401 RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGL 2460
            R S G+   G G G+      GR G G      ++ +G         GP + GS H S  
Sbjct: 234  RSSGGYEPRGRGGGRG-----GRGGMGGSDRGGFNKFG---------GPRDQGSRHDSEQ 279

Query: 2461 GHRESRSGQSSGYGQH----------------------GSSSGHSSTHGQHGSTSGQS-- 2496
             + ++ +    G G++                      G    +  T  + G   G++  
Sbjct: 280  DNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATV 339

Query: 2497 SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS 2556
            S      A +      G+  SG+     +  + +   +  G+G+ G G R  P  GR G 
Sbjct: 340  SFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRG-RGGP-MGRGGY 397

Query: 2557 GSGRSSSSGQHGSGLGESSGFGHHESS-------SGQSSSYSQHG----------SGSGH 2599
            G G S   G+ G   G   G G   +        + ++ ++S              G G 
Sbjct: 398  GGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGG 457

Query: 2600 SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHG-RQGSGSGQSPSRGRH 2658
              G    G   G   RG R G   G     G    G R   G G R G G G+  SRG H
Sbjct: 458  GPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEH 517



 Score =  133 bits (335), Expect = 2e-30
 Identities = 153/542 (28%), Positives = 211/542 (38%), Gaps = 79/542 (14%)

Query: 1699 SSGHGRQGSGS-GQSPSRGRHGSGLGHSSSHGQHG-SGSGRSSSRGPYESRSGHSSVFGQ 1756
            S+ + +Q + S G  P++   G     S  +GQ   SG  +S+    Y  +S +SS    
Sbjct: 3    SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGY-GQSSYSSYGQS 61

Query: 1757 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQS 1816
              +G G  S    +GS  G+  SQ    S+ GQ S++   G     SS+ G +GS SSQS
Sbjct: 62   QNTGYGTQSTPQGYGSTGGYGSSQSSQ-SSYGQQSSYPGYGQQPAPSSTSGSYGS-SSQS 119

Query: 1817 SSYGQQGSGS-GQSPSRGRHGSGSGHSSSYGQ---HGSGSGWSSSSGRHGSGSGQSSGFG 1872
            SSYGQ  SGS  Q PS G      G   SY     +G  + ++SSSG  G G G    +G
Sbjct: 120  SSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSG-GGGGGGGGGNYG 178

Query: 1873 HHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQ 1932
              +SS   SSG    GSG G+                G Q  S  G S  YGQ   G R 
Sbjct: 179  QDQSS--MSSG---GGSGGGY----------------GNQDQSGGGGSGGYGQQDRGGRG 217

Query: 1933 SLGHGQHGSGSGQSPSPSRGRH---GSGSGQSSSYGPYGSG-SGWSSSRGPYESGSGHSS 1988
              G G  G G G   + S G +   G G G+    G  GS   G++   GP + GS H S
Sbjct: 218  RGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDS 277

Query: 1989 GLGHRESRSGQSSGYGQH----------------------GSSSGHSSTHGQHGSASGQS 2026
               + ++ +    G G++                      G    +  T  + G   G++
Sbjct: 278  EQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEA 337

Query: 2027 --SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 2084
              S      A +      G+  SG+     +  + +   +  G+G+ G G R  P  GR 
Sbjct: 338  TVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRG-RGGP-MGRG 395

Query: 2085 GSGSGRSSSSGQHGPGLGESSGFGHHESS-------SGQSSSYSQHG----------SGS 2127
            G G G S   G+ G   G   G G   +        + ++ ++S              G 
Sbjct: 396  GYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGP 455

Query: 2128 GHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHG-RQGSGSGHSPSRG 2186
            G   G    G   G   RG R G   G     G    G R   G G R G G G   SRG
Sbjct: 456  GGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRG 515

Query: 2187 RH 2188
             H
Sbjct: 516  EH 517



 Score =  130 bits (326), Expect = 2e-29
 Identities = 143/543 (26%), Positives = 191/543 (35%), Gaps = 94/543 (17%)

Query: 1485 GSGSGQSSSYSPYG--SGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGH 1542
            G G  Q SS  PYG  S SG+S S      G S  S  G       Q++GYG   +  G+
Sbjct: 22   GQGYSQQSS-QPYGQQSYSGYSQSTDTSGYGQSSYSSYGQ-----SQNTGYGTQSTPQGY 75

Query: 1543 SSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 1602
             ST G   S S QSS         GQ SS+           GYG+Q + S  S   G  G
Sbjct: 76   GSTGGYGSSQSSQSSY--------GQQSSY----------PGYGQQPAPSSTS---GSYG 114

Query: 1603 SGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS-----GQSSSYSQHGSGS 1657
            S S QS SYG+  SG     S  Q  S  G+   +G  +S +     GQ + Y+    G 
Sbjct: 115  SSS-QSSSYGQPQSG-----SYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGG 168

Query: 1658 GHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGS---GSRQSSGHGRQGSGSGQSPS 1714
            G   G G +G      S G   G    +  + G  GS   G +   G GR GSG G    
Sbjct: 169  GGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGG 228

Query: 1715 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS 1774
             G +    G     G+ G   GR    G    R G +   G  + GS H S      + +
Sbjct: 229  GGGYNRSSGGYEPRGRGGGRGGRGGMGG--SDRGGFNKFGGPRDQGSRHDSEQDNSDNNT 286

Query: 1775 GHFCSQGQHGSTSGQSSTFDQEG-----SSTGQSSSH----------------------- 1806
                  G++ +    +  F Q G       TGQ   +                       
Sbjct: 287  IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPS 346

Query: 1807 ---------GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSS 1857
                     G+  SG+    S+  + +   +    GR G G G     G+ G G G S  
Sbjct: 347  AKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRG--GPMGRGGYGGGGSGG 404

Query: 1858 SGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSS 1917
             GR G  SG   G G   +  W+    T         +   Q      ++ + +  G   
Sbjct: 405  GGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQ-----CKAPKPDGPGGGP 459

Query: 1918 GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSR 1977
            G S   G +G   R   G    G   G+       R G G G    +GP     G   SR
Sbjct: 460  GGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGP-----GKMDSR 514

Query: 1978 GPY 1980
            G +
Sbjct: 515  GEH 517



 Score =  128 bits (322), Expect = 7e-29
 Identities = 151/537 (28%), Positives = 205/537 (38%), Gaps = 65/537 (12%)

Query: 2278 QHGSGSSQSSS--YGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 2335
            Q G G SQ SS  YGQQ S SG S S    G G    SSYGQ    +G+ + S   G GS
Sbjct: 20   QPGQGYSQQSSQPYGQQ-SYSGYSQSTDTSGYGQSSYSSYGQ-SQNTGYGTQSTPQGYGS 77

Query: 2336 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQ 2395
              + G+G  +SS           S  G  SSY  +G +   SS    +GSSS  SSSYGQ
Sbjct: 78   --TGGYGSSQSSQ----------SSYGQQSSYPGYGQQPAPSSTSGSYGSSS-QSSSYGQ 124

Query: 2396 HGSGS---RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSG--WSSSRGPY 2450
              SGS   + S G  Q   G  QS +P +G        SSS    G G G  +   +   
Sbjct: 125  PQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSM 184

Query: 2451 ESGSGHSSGLGHR-ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQS 2509
             SG G   G G++ +S  G S GYGQ           G+ GS  G     G +  SSG  
Sbjct: 185  SSGGGSGGGYGNQDQSGGGGSGGYGQQDRGG-----RGRGGSGGGGGGGGGGYNRSSGGY 239

Query: 2510 SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGS 2569
               G+ G       G G +G   G   G   +  G R   S  RH S    S ++     
Sbjct: 240  EPRGRGG-------GRGGRGGMGGSDRGGFNKFGGPRDQGS--RHDSEQDNSDNNTIFVQ 290

Query: 2570 GLGES---SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSS 2626
            GLGE+        +    G   +  + G    +     + G   G+++       S+ ++
Sbjct: 291  GLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAA 350

Query: 2627 SHY--GQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPY 2684
              +  G+  SG+        + +   +    GR G G G     G +G G      RG +
Sbjct: 351  IDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGF 410

Query: 2685 ESRLGHSSVFGQHESGSGH--SSAYSQHGSGSGHFCSQ-----------GQHGSTSGQSS 2731
             S  G     GQ  +G     +           + C+Q           G  GS  G + 
Sbjct: 411  PS--GGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNY 468

Query: 2732 TFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQH 2788
              D+ G   G     G+RG G  +    G  G G        R G G G+  S G+H
Sbjct: 469  GDDRRGGRGGYDRG-GYRGRGGDRGGFRGGRGGGD-------RGGFGPGKMDSRGEH 517



 Score =  128 bits (321), Expect = 9e-29
 Identities = 151/569 (26%), Positives = 206/569 (36%), Gaps = 83/569 (14%)

Query: 475  SSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHG-SGSRQSLGHSRH 533
            S+ YTQ  + S     +G + ++ GQ       G S  SS  YGQ   SG  QS   S +
Sbjct: 3    SNDYTQQATQS-----YGAYPTQPGQ-------GYSQQSSQPYGQQSYSGYSQSTDTSGY 50

Query: 534  GSGSGQSPSPSRGRHESGSRQSSSYG----PHGYGSGRSSSRGPYESGSGHSSGLGHQES 589
            G  S  S          G  Q++ YG    P GYGS      G Y S     S  G Q S
Sbjct: 51   GQSSYSS---------YGQSQNTGYGTQSTPQGYGS-----TGGYGSSQSSQSSYGQQSS 96

Query: 590  RSGQ------SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGS-- 641
              G       SS  G +GSSS  SS++GQ      QS S  Q  +  GQ  S+GQ  S  
Sbjct: 97   YPGYGQQPAPSSTSGSYGSSS-QSSSYGQ-----PQSGSYSQQPSYGGQQQSYGQQQSYN 150

Query: 642  ---GSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQS 698
               G  Q ++Y     G G     G +G D    SS G  G G G    +G      G S
Sbjct: 151  PPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSG-----GGGS 205

Query: 699  SGFGHKSGSGQSSGYSQHGSG------SSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSY 752
             G+G +   G+  G S  G G      +  S GY   G   G+  R    GS  G    +
Sbjct: 206  GGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRG---GF 262

Query: 753  GQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSG 812
             + G    Q S H  +   S ++   V+    +    S   +        +  + ++G  
Sbjct: 263  NKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKT--NKKTGQP 320

Query: 813  QASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHES 872
              + +   E+G  +G           S      + +      G+  S +    S+    +
Sbjct: 321  MINLYTDRETGKLKG-------EATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRA 373

Query: 873  ASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSG------- 925
              +   G GR G G G   G G  G G G S   GR G  SG     G+  +G       
Sbjct: 374  DFNRGGGNGRGGRGRGGPMGRG--GYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNP 431

Query: 926  SGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQ 985
            + ++  F  ++   Q       G G G   S+   G   G   R  + G   G     G 
Sbjct: 432  TCENMNFSWRNECNQCKAPKPDGPGGGPGGSH--MGGNYGDDRRGGRGGYDRGGYRGRGG 489

Query: 986  HGSGSRQSLGHGQHGSGSGQSPSPSRGRH 1014
               G R   G G  G G G     SRG H
Sbjct: 490  DRGGFRGGRGGGDRG-GFGPGKMDSRGEH 517



 Score =  128 bits (321), Expect = 9e-29
 Identities = 138/533 (25%), Positives = 185/533 (34%), Gaps = 116/533 (21%)

Query: 1955 GSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 2014
            G G  Q SS  PYG  S    S+    SG G SS   + +S   Q++GYG   +  G+ S
Sbjct: 22   GQGYSQQSSQ-PYGQQSYSGYSQSTDTSGYGQSSYSSYGQS---QNTGYGTQSTPQGYGS 77

Query: 2015 THGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSG 2074
            T G +GS+    SS GQ  +  G    +GQ  + SS S  YG     S QS  +GQ  SG
Sbjct: 78   TGG-YGSSQSSQSSYGQQSSYPG----YGQQPAPSSTSGSYG----SSSQSSSYGQPQSG 128

Query: 2075 S-RQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGY 2133
            S  Q PSYG      G+  S   + P  G            GQ + Y+    G G   G 
Sbjct: 129  SYSQQPSYGGQQQSYGQQQS---YNPPQGY-----------GQQNQYNSSSGGGGGGGGG 174

Query: 2134 GQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGS---RQSSGHGRQGSGSGHSPSRGRHGS 2190
            G +G      S G   G   G+  + G  GSG    +   G GR GSG G     G +  
Sbjct: 175  GNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNR 234

Query: 2191 GSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ 2250
             SG     G+ G   GR    G    R G +   G  + GS H S      + +      
Sbjct: 235  SSGGYEPRGRGGGRGGRGGMGG--SDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGL 292

Query: 2251 GQHGSTSGQSSTFDQEG-----SSTGQSSSH----------------------------- 2276
            G++ +    +  F Q G       TGQ   +                             
Sbjct: 293  GENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAID 352

Query: 2277 ---GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS 2333
               G+  SG+    S+  + +   +    GR G G G     G+ G G G S   GR G 
Sbjct: 353  WFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRG--GPMGRGGYGGGGSGGGGRGGF 410

Query: 2334 GSGQSSGFGHHESSSWQSSGYT-------------------QHGSGSGHSSSY------- 2367
             SG   G G   +  W+    T                     G G G   S+       
Sbjct: 411  PSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGD 470

Query: 2368 EQHGSRSGQS------------------SRGERHGSSSGSSSSYGQHGSGSRQ 2402
            ++ G R G                      G+R G   G   S G+H    R+
Sbjct: 471  DRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRE 523



 Score =  127 bits (318), Expect = 2e-28
 Identities = 148/544 (27%), Positives = 212/544 (38%), Gaps = 83/544 (15%)

Query: 1229 SSGHGRQGSGS-GHSPSRGRHGSGLGHSSSHGQHG-SGSGRSSSRGPYESRSGHSSVFGQ 1286
            S+ + +Q + S G  P++   G     S  +GQ   SG  +S+    Y  +S +SS    
Sbjct: 3    SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGY-GQSSYSSYGQS 61

Query: 1287 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQS 1346
              +G G  S    +GS  G+  SQ    S+ GQ S++   G     SS+ G  GS SSQS
Sbjct: 62   QNTGYGTQSTPQGYGSTGGYGSSQSSQ-SSYGQQSSYPGYGQQPAPSSTSGSYGS-SSQS 119

Query: 1347 SGYGRHGAGS-GQSPSRGRHGSGSGHSSSYGQ---HGSGSGWSSSSGRHGSGSGQSSGFG 1402
            S YG+  +GS  Q PS G      G   SY     +G  + ++SSSG  G G G    +G
Sbjct: 120  SSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSG-GGGGGGGGGNYG 178

Query: 1403 HHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSG--S 1460
              +SS   SSG    GSG G+ +  +  G  SG   + +R G   G S   G  G G  +
Sbjct: 179  QDQSS--MSSG---GGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYN 233

Query: 1461 RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGL 1520
            R S G+   G G G+      GR G G      ++ +G         GP + GS H S  
Sbjct: 234  RSSGGYEPRGRGGGRG-----GRGGMGGSDRGGFNKFG---------GPRDQGSRHDSEQ 279

Query: 1521 GHRESRSGQSSGYGQH----------------------GSSSGHSSTHGQHGSTSGQSSS 1558
             + ++ +    G G++                      G    +  T  + G   G+++ 
Sbjct: 280  DNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATV 339

Query: 1559 C---------------GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGS 1603
                            G+  + +    S     +  ++  G GR G G G   G G  G 
Sbjct: 340  SFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGG 399

Query: 1604 GSRQSPSYGRHGSGSGRSSSSGQHGSG-------LGESSGFG-HHESSSGQSSSYSQHGS 1655
            G   S   GR G  SG     GQ  +G         E+  F   +E +  ++      G 
Sbjct: 400  GG--SGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGG 457

Query: 1656 GSGHSSGYGQHG-SRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPS 1714
            G G S   G +G  R G     +R G   R   R G  G       G  R G G G+  S
Sbjct: 458  GPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGG----RGGGDRGGFGPGKMDS 513

Query: 1715 RGRH 1718
            RG H
Sbjct: 514  RGEH 517



 Score =  123 bits (309), Expect = 2e-27
 Identities = 153/550 (27%), Positives = 207/550 (37%), Gaps = 92/550 (16%)

Query: 749  SSSYG----QHGSG-SHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQH---GSGTSC 800
            + SYG    Q G G S QSS    Q S SG+S S    G      SS+GQ    G GT  
Sbjct: 11   TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQS 70

Query: 801  SSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSS 860
            +        G G   G+G  +S S   Y Q  S  G+       G     SS+SG + SS
Sbjct: 71   TPQ------GYGSTGGYGSSQS-SQSSYGQQSSYPGY-------GQQPAPSSTSGSYGSS 116

Query: 861  SGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGR---HGSGSGRSS 917
            S QSSSYGQ +S S+             Q P +G +    GQ  SY     +G  +  +S
Sbjct: 117  S-QSSSYGQPQSGSY------------SQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNS 163

Query: 918  SSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSS 977
            SSG  G G G    +G   SS  S G    GSG G+ +  +  G  SG   + ++ G   
Sbjct: 164  SSGGGGGGGG-GGNYGQDQSSMSSGG----GSGGGYGNQDQSGGGGSGGYGQQDRGGRGR 218

Query: 978  GSSSSYGQHGSG--SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY----GPYRSGS 1031
            G S   G  G G  +R S G+   G G G+      GR G G      +    GP   GS
Sbjct: 219  GGSGGGGGGGGGGYNRSSGGYEPRGRGGGRG-----GRGGMGGSDRGGFNKFGGPRDQGS 273

Query: 1032 GWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST---------HGQHGST 1082
               S +   ++ +    GLG   +    +  + Q G    +  T           + G  
Sbjct: 274  RHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKL 333

Query: 1083 SGQSSSCGQHGASSGQSSS--HGQHGSGS-------------SQSSGYGRQGSGSGQSPG 1127
             G+++       S+  +     G+  SG+             ++  G GR G G G   G
Sbjct: 334  KGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMG 393

Query: 1128 HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSG-------LGESSGFG-HHESSSGQSSS 1179
             G  G G   S   GR G  SG     GQ  +G         E+  F   +E +  ++  
Sbjct: 394  RGGYGGGG--SGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPK 451

Query: 1180 YSQHGSGSGHSSGYGQHGS--RSGQSS--RGERHGSSSGSSSHYGQHGSGSRQSSGHGRQ 1235
                G G G S   G +G   R G+    RG   G         G  G G R   G G+ 
Sbjct: 452  PDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKM 511

Query: 1236 GSGSGHSPSR 1245
             S   H   R
Sbjct: 512  DSRGEHRQDR 521



 Score =  123 bits (309), Expect = 2e-27
 Identities = 155/557 (27%), Positives = 195/557 (35%), Gaps = 143/557 (25%)

Query: 1961 SSSYGPYGS--GSGWSS-SRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG 2017
            + SYG Y +  G G+S  S  PY    G  S  G+  S+S  +SGYGQ   SS       
Sbjct: 11   TQSYGAYPTQPGQGYSQQSSQPY----GQQSYSGY--SQSTDTSGYGQSSYSS------- 57

Query: 2018 QHGSASGQSSSCGQHGASSGQS-SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 2076
                  GQS + G    S+ Q   S G +GS  S  S YG+Q S     PG+GQ+ + S 
Sbjct: 58   -----YGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSS----YPGYGQQPAPSS 108

Query: 2077 QSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQH 2136
             S SYG     S +SSS GQ                   QS SYSQ  S  G    YGQ 
Sbjct: 109  TSGSYG----SSSQSSSYGQP------------------QSGSYSQQPSYGGQQQSYGQQ 146

Query: 2137 GSRSGQSSRGER--HGSSS------GSSSRYGQH----GSGSRQSSGHGRQ----GSGSG 2180
             S +     G++  + SSS      G    YGQ      SG     G+G Q    G GSG
Sbjct: 147  QSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSG 206

Query: 2181 HSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYE-----------------SRSGHSSV 2223
                + R G G G  S  G  G G G + S G YE                  R G +  
Sbjct: 207  GYGQQDRGGRGRG-GSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKF 265

Query: 2224 FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEG-----SSTGQSSSH-- 2276
             G  + GS H S      + +      G++ +    +  F Q G       TGQ   +  
Sbjct: 266  GGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLY 325

Query: 2277 ------------------------------GQHGSGSSQSSSYGQQGSGSGQSPSRGRHG 2306
                                          G+  SG+    S+  + +   +    GR G
Sbjct: 326  TDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGG 385

Query: 2307 SGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYT----------- 2355
             G G     G+ G G G S   GR G  SG   G G   +  W+    T           
Sbjct: 386  RGRG--GPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNE 443

Query: 2356 --------QHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHG 2407
                      G G G   S+   G   G   RG R G   G     G    G R   G G
Sbjct: 444  CNQCKAPKPDGPGGGPGGSH--MGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGG 501

Query: 2408 QHGSGSGQSPSPSRGRH 2424
              G G G     SRG H
Sbjct: 502  DRG-GFGPGKMDSRGEH 517



 Score =  123 bits (309), Expect = 2e-27
 Identities = 121/403 (30%), Positives = 160/403 (39%), Gaps = 27/403 (6%)

Query: 2425 GSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 2484
            G G  Q SS  PYG  S    S+    SG G SS   + +S   Q++GYG   +  G+ S
Sbjct: 22   GQGYSQQSS-QPYGQQSYSGYSQSTDTSGYGQSSYSSYGQS---QNTGYGTQSTPQGYGS 77

Query: 2485 THGQHGSTS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS-GQSPGH 2538
            T G   S S     GQ SS   +G     SS+ G +GS SSQSS YG+  SGS  Q P +
Sbjct: 78   TGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS-SSQSSSYGQPQSGSYSQQPSY 136

Query: 2539 G--QRGSGSRQS--PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSY---S 2591
            G  Q+  G +QS  P  G        SSS G  G G G + G      SSG  S     +
Sbjct: 137  GGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGN 196

Query: 2592 QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQ 2651
            Q  SG G S GYGQ   R G+   G   G   G   +    G    +  G GR G G   
Sbjct: 197  QDQSGGGGSGGYGQQ-DRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMG 255

Query: 2652 SPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVF---GQHESGSGHSSAYS 2708
               RG      G      +H S    S +   +   LG +        +    G      
Sbjct: 256  GSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNK 315

Query: 2709 QHGSGSGHFCSQGQHGSTSGQSS-TFDQEGSSTGQSSSY-GHRGSGSSQSSGYGRHGAGS 2766
            + G    +  +  + G   G+++ +FD   S+      + G   SG+     +    A  
Sbjct: 316  KTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADF 375

Query: 2767 GQSLSHGRHGSGSG---QSSSYGQHGSGSGQSSGYSQHGSGSG 2806
             +   +GR G G G       YG  GSG G   G+   G G G
Sbjct: 376  NRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGG 418



 Score =  121 bits (304), Expect = 9e-27
 Identities = 160/558 (28%), Positives = 205/558 (36%), Gaps = 89/558 (15%)

Query: 646  SSRYGQQGSGS-GQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHK 704
            S+ Y QQ + S G  P++   G     S  YGQ  S SG+S S                 
Sbjct: 3    SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQ-SYSGYSQSTDT-------------- 47

Query: 705  SGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSG 764
            SG GQSS YS +G   S ++GY    +  G  S    +GSS    SSYGQ  S      G
Sbjct: 48   SGYGQSS-YSSYGQ--SQNTGYGTQSTPQGYGSTGG-YGSSQSSQSSYGQQSS----YPG 99

Query: 765  HGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHES-G 823
            +G+Q + S  S S   +GSSS  SSS+GQ  SG     S     S  GQ   +GQ +S  
Sbjct: 100  YGQQPAPSSTSGS---YGSSS-QSSSYGQPQSG-----SYSQQPSYGGQQQSYGQQQSYN 150

Query: 824  SGQGY---SQHGSASGHFSSQGRHGS--------TSGQSSSSG---QHDSSSGQSSSYGQ 869
              QGY   +Q+ S+SG     G  G+        +SG  S  G   Q  S  G S  YGQ
Sbjct: 151  PPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQ 210

Query: 870  HESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQS 929
             +       GRGR GSG G   G G     SG    Y   G G GR    G  GS  G  
Sbjct: 211  QDRG-----GRGRGGSGGGGGGGGGGYNRSSG---GYEPRGRGGGRGGRGGMGGSDRGGF 262

Query: 930  SGFG--------HKSSSGQSSGYTQHGSGSGHSSSYE------------QHGSRSGQSS- 968
            + FG        H S    S   T    G G + + E            +   ++GQ   
Sbjct: 263  NKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMI 322

Query: 969  ---RSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYG 1025
                  + G   G ++        ++ ++        SG     S     +   +    G
Sbjct: 323  NLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNG 382

Query: 1026 PYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQ 1085
                G G    RG Y  G G S G G     SG   G GQ  +                 
Sbjct: 383  RGGRGRGGPMGRGGY--GGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSW 440

Query: 1086 SSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG--- 1142
             + C Q  A        G  GS    + G  R+G   G   G G RG G  +    G   
Sbjct: 441  RNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRG-GYRGRGGDRGGFRGGRG 499

Query: 1143 ---RHGSGSGRSSSSGQH 1157
               R G G G+  S G+H
Sbjct: 500  GGDRGGFGPGKMDSRGEH 517



 Score =  121 bits (303), Expect = 1e-26
 Identities = 145/539 (26%), Positives = 193/539 (35%), Gaps = 73/539 (13%)

Query: 1764 SSAYSQHGSGS-GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQ 1822
            S+ Y+Q  + S G + +Q   G +   S  + Q+ S +G S S    G G S  SSYGQ 
Sbjct: 3    SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQ-SYSGYSQSTDTSGYGQSSYSSYGQS 61

Query: 1823 ---GSGSGQSP----SRGRHGSGSGHSSSYGQHGSGSGW------SSSSGRHGSGSGQSS 1869
               G G+  +P    S G +GS     SSYGQ  S  G+      SS+SG +GS S QSS
Sbjct: 62   QNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS-SSQSS 120

Query: 1870 GFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSG 1929
             +G  +S S     Y+Q  S  G   SY Q  S +     G+Q+  +S S    G  G G
Sbjct: 121  SYGQPQSGS-----YSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGG 175

Query: 1930 SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSG 1989
            +           G  QS   S G  G G G     G  GSG      RG    G     G
Sbjct: 176  N----------YGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGG 225

Query: 1990 LGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGS 2049
             G     +  S GY   G   G     G  GS  G      + G    Q S H      S
Sbjct: 226  GGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRG---GFNKFGGPRDQGSRHDSEQDNS 282

Query: 2050 SQSS----GYGRQGSGSGQSPGHGQRG-------SGSRQSPSYGRHGSG--SGRSSSSGQ 2096
              ++    G G   +    +    Q G       +G      Y    +G   G ++ S  
Sbjct: 283  DNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD 342

Query: 2097 HGPGLGESSGFGHHESSSGQ--SSSYSQHGSGSGHSSGYGQHG-SRSGQSSRGERHGSSS 2153
              P    +  +   +  SG     S++   +      G G+ G  R G   RG   G  S
Sbjct: 343  DPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGS 402

Query: 2154 GSSSRYGQHGSGSRQSSGHGRQGSGSGHSP-------------------SRGRHGSGSGH 2194
            G   R G    G     G G+Q +G    P                   +    G G G 
Sbjct: 403  GGGGRGGFPSGG---GGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGP 459

Query: 2195 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQH 2253
              SH     G  R   RG Y+ R G+    G      G      + G G G   S+G+H
Sbjct: 460  GGSHMGGNYGDDRRGGRGGYD-RGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEH 517



 Score =  119 bits (299), Expect = 3e-26
 Identities = 147/543 (27%), Positives = 202/543 (37%), Gaps = 63/543 (11%)

Query: 1333 SSSYG----HRGSGSSQSSG--YGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS 1386
            + SYG      G G SQ S   YG+    SG S S    G G    SSYGQ    +G+ +
Sbjct: 11   TQSYGAYPTQPGQGYSQQSSQPYGQQSY-SGYSQSTDTSGYGQSSYSSYGQ-SQNTGYGT 68

Query: 1387 SSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSS 1446
             S   G GS  + G+G  +SS           S  G  SSY  +G +   SS    +GSS
Sbjct: 69   QSTPQGYGS--TGGYGSSQSSQ----------SSYGQQSSYPGYGQQPAPSSTSGSYGSS 116

Query: 1447 SGSSSSYGQHGSGS---RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGW 1503
            S  SSSYGQ  SGS   + S G  Q   G  QS +P +G +G    Q +S S  G G G 
Sbjct: 117  S-QSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQG-YGQ-QNQYNSSSGGGGGGGG 173

Query: 1504 SSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHG 1563
              + G  +S  S   G G       QS G G  G         G+ GS  G     G + 
Sbjct: 174  GGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYN 233

Query: 1564 ASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSS 1623
             SSG     G+ G       G G +G   G   G   +  G R   S  RH S    S +
Sbjct: 234  RSSGGYEPRGRGG-------GRGGRGGMGGSDRGGFNKFGGPRDQGS--RHDSEQDNSDN 284

Query: 1624 SGQHGSGLGES---SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG 1680
            +     GLGE+        +    G   +  + G    +     + G   G+++      
Sbjct: 285  NTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDP 344

Query: 1681 SSSRSSSRY--GQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRS 1738
             S++++  +  G+  SG+        + +   +    GR G G G     G +G G    
Sbjct: 345  PSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGG 404

Query: 1739 SSRGPYESRSGHSSVFGQHESGSGH--SSAYSQHGSGSGHFCSQ-----------GQHGS 1785
              RG + S  G     GQ  +G     +           + C+Q           G  GS
Sbjct: 405  GGRGGFPSGGGGGG--GQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGS 462

Query: 1786 TSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSY 1845
              G +   D+ G   G     G  G G  +    G +G G        R G G G   S 
Sbjct: 463  HMGGNYGDDRRGGRGGYDRG-GYRGRGGDRGGFRGGRGGGD-------RGGFGPGKMDSR 514

Query: 1846 GQH 1848
            G+H
Sbjct: 515  GEH 517



 Score =  115 bits (287), Expect = 8e-25
 Identities = 146/574 (25%), Positives = 205/574 (35%), Gaps = 71/574 (12%)

Query: 176 SSSYGEQNSDSHQSSGRGQCGSGSGQ--SPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQ 233
           S+ Y +Q + S+ +    Q G G  Q  S  YGQ  S SG S S DT G G    S + Q
Sbjct: 3   SNDYTQQATQSYGAYPT-QPGQGYSQQSSQPYGQQ-SYSGYSQSTDTSGYGQSSYSSYGQ 60

Query: 234 HKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGER-----HRSSSGSSSSYGQHGS 288
                 Q++GY    +  G+ S  G   S+S QSS G++     +      SS+ G +GS
Sbjct: 61  -----SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS 115

Query: 289 GSRQS-LGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSG 347
            S+ S  G  + GS S+Q PS+       G   S+GQ     SY+  +G+     GQ + 
Sbjct: 116 SSQSSSYGQPQSGSYSQQ-PSY------GGQQQSYGQQ---QSYNPPQGY-----GQQNQ 160

Query: 348 FGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESAS 407
           +     G G   G   +G      SS G  G   G    SG  G     S  YGQ +   
Sbjct: 161 YNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGG-----SGGYGQQDRGG 215

Query: 408 RHSSGRGQHSSGSG-----QSPGHGQRGSGSGQSPSSGQHGTGFGR-SSSSGPYVSGSGY 461
           R   G G    G G      S G+  RG G G+    G  G+  G  +   GP   GS  
Sbjct: 216 RGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGS-- 273

Query: 462 SSGFGHHESSSEHSSGYTQHGSGSGHS---SGHGQHGSRSGQSSRGERQGSSAGSSSSYG 518
                 H+S  ++S   T    G G +        +  + G     ++ G    +  +  
Sbjct: 274 -----RHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDR 328

Query: 519 QHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGS 578
           + G    ++         +  +     G+  SG+    S+        R    G    G 
Sbjct: 329 ETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGR 388

Query: 579 GHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQ 638
           G   G G          GYG  GS  G     G+ G  SG     GQ  A   +  +   
Sbjct: 389 GGPMGRG----------GYGGGGSGGG-----GRGGFPSGGGGGGGQQRAGDWKCPNPTC 433

Query: 639 HGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQS 698
                S  +   Q  +     P  G  GS  G   +YG    G       G +    G  
Sbjct: 434 ENMNFSWRNECNQCKAPKPDGPGGGPGGSHMG--GNYGDDRRGGRGGYDRGGYRGRGGDR 491

Query: 699 SGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSR 732
            GF    G G   G+   G G   S G  +   R
Sbjct: 492 GGFRGGRGGGDRGGF---GPGKMDSRGEHRQDRR 522



 Score =  114 bits (286), Expect = 1e-24
 Identities = 136/514 (26%), Positives = 187/514 (36%), Gaps = 93/514 (18%)

Query: 172 YSGQSSS-YGEQN----SDSHQSSGRGQCGSGS-GQSPNYGQHGSGSGQSSSNDTHGSGS 225
           YS QSS  YG+Q+    S S  +SG GQ    S GQS N G +G+ S       T G GS
Sbjct: 25  YSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTG-YGTQSTPQGYGSTGGYGS 83

Query: 226 GQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSY-G 284
            QSS     +SS GQ S Y  +G     SS  G +GS S  SS G+    S     SY G
Sbjct: 84  SQSS-----QSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGG 138

Query: 285 QHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQ 344
           Q  S  +Q   +  QG G +   +    G G G        G G +Y   +    SG G 
Sbjct: 139 QQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGG--------GGGGNYGQDQSSMSSGGGS 190

Query: 345 TSGFG-QHESGSGQSSGYSKH---------------GSGSGHSSSQGQH---GSTSGQAS 385
             G+G Q +SG G S GY +                G G G++ S G +   G   G+  
Sbjct: 191 GGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGG 250

Query: 386 SSGQHGSSSRQSSSY-GQHESASRHSSGRGQHSSGSGQSPGHGQR--------------- 429
             G  GS     + + G  +  SRH S +    + +    G G+                
Sbjct: 251 RGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGI 310

Query: 430 ---GSGSGQ-----------SPSSGQHGTGFGRSSSS--------GPYVSGSGYSSGFGH 467
                 +GQ               G+    F    S+        G   SG+     F  
Sbjct: 311 IKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFAT 370

Query: 468 HESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSG---- 523
             +      G  + G G G   G G +G   G S  G R G  +G     GQ  +G    
Sbjct: 371 RRADFNRGGGNGRGGRGRGGPMGRGGYG--GGGSGGGGRGGFPSGGGGGGGQQRAGDWKC 428

Query: 524 ---SRQSLGHS-RHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSG 579
              + +++  S R+     ++P P       G     S+    YG  R   RG Y+ G  
Sbjct: 429 PNPTCENMNFSWRNECNQCKAPKPD----GPGGGPGGSHMGGNYGDDRRGGRGGYDRGGY 484

Query: 580 HSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQH 613
              G      R G+  G  + G   G   + G+H
Sbjct: 485 RGRGGDRGGFRGGRGGG-DRGGFGPGKMDSRGEH 517



 Score =  111 bits (277), Expect = 1e-23
 Identities = 143/559 (25%), Positives = 197/559 (35%), Gaps = 84/559 (15%)

Query: 303 SRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHES--GSGQSSG 360
           S+QS       S SG+S S    G G S SYS      G  Q +G+G   +  G G + G
Sbjct: 26  SQQSSQPYGQQSYSGYSQSTDTSGYGQS-SYS----SYGQSQNTGYGTQSTPQGYGSTGG 80

Query: 361 YSKHGSGSGHSSSQGQHGSTSGQ------ASSSGQHGSSSRQSSSYGQHESAS---RHSS 411
           Y   GS     SS GQ  S  G       +S+SG +GSSS QSSSYGQ +S S   + S 
Sbjct: 81  Y---GSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSS-QSSSYGQPQSGSYSQQPSY 136

Query: 412 GRGQHSSGSGQS----PGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGH 467
           G  Q S G  QS     G+GQ+   +  S   G  G G           SG G   G+G+
Sbjct: 137 GGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGN 196

Query: 468 HESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQS 527
            + S    SG    G G     G G+ GS  G    G                G  +R S
Sbjct: 197 QDQSGGGGSG----GYGQQDRGGRGRGGSGGGGGGGG----------------GGYNRSS 236

Query: 528 LGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQ 587
            G+   G G G+      G  + G       GP   GS   S +   ++ +    GLG  
Sbjct: 237 GGYEPRGRGGGRGGRGGMGGSDRGGFNKFG-GPRDQGSRHDSEQDNSDNNTIFVQGLGEN 295

Query: 588 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSS 647
            +    +  + Q G    +  T    G       +  + G   G+++        +  + 
Sbjct: 296 VTIESVADYFKQIGIIKTNKKT----GQPMINLYTDRETGKLKGEATVSFDDPPSAKAAI 351

Query: 648 RY--GQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKS 705
            +  G++ SG+    S     +DF      G+ G G G     G +G         G  S
Sbjct: 352 DWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYG---------GGGS 402

Query: 706 GSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGH 765
           G G   G+   G G     G ++ G     +   E    S    +   Q  +      G 
Sbjct: 403 GGGGRGGFPSGGGG---GGGQQRAGDWKCPNPTCENMNFS--WRNECNQCKAPKPDGPGG 457

Query: 766 GRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSG 825
           G  GS  G +    R G   G+                 G Y    G   GF     G  
Sbjct: 458 GPGGSHMGGNYGDDRRGGRGGYDR---------------GGYRGRGGDRGGFRGGRGGGD 502

Query: 826 QGYSQHGSASGHFSSQGRH 844
           +G    G   G   S+G H
Sbjct: 503 RG----GFGPGKMDSRGEH 517



 Score = 92.4 bits (228), Expect = 6e-18
 Identities = 124/483 (25%), Positives = 170/483 (35%), Gaps = 69/483 (14%)

Query: 128 SHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQ------SSSYGE 181
           S+SS+   +N  Y           T       S Q  + GQ +SY G       SS+ G 
Sbjct: 54  SYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSY-GQQSSYPGYGQQPAPSSTSGS 112

Query: 182 QNSDSHQSSGRGQCGSGS--------GQSPNYGQHGS-----GSGQ-----SSSNDTHGS 223
             S S QSS  GQ  SGS        GQ  +YGQ  S     G GQ     SSS    G 
Sbjct: 113 YGSSS-QSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGG 171

Query: 224 GSGQSSGFSQHKSSSGQSSGY---SQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSS 280
           G G + G  Q   SSG  SG    +Q  SG G S GYGQ         RG R R  SG  
Sbjct: 172 GGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQ-------DRGGRGRGGSGGG 224

Query: 281 SSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSG-SGHSSSHGQHGSGSSYSYSRGHYE 339
              G  G  +R S G+  +G G  +       GS   G +   G    GS +   + + +
Sbjct: 225 GG-GGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSD 283

Query: 340 SGSGQTSGFGQHESGSGQSSGY---------SKHGSGSGHSSSQGQHGSTSGQASSSGQH 390
           + +    G G++ +    +  +          K G    +  +  + G   G+A+ S   
Sbjct: 284 NNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDD 343

Query: 391 GSSSRQSSSY--GQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGR 448
             S++ +  +  G+  S +          +   +  G+G+ G G G     G +G G   
Sbjct: 344 PPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSG 403

Query: 449 SSSSGPYVSGSGYSSGFGHHESS-----------------SEHSSGYTQHGSGSGHSSGH 491
               G + SG G   G G   +                  +E +        G G   G 
Sbjct: 404 GGGRGGFPSGGG--GGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGG 461

Query: 492 GQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESG 551
              G   G   RG R G   G     G    G R   G    G G G     SRG H   
Sbjct: 462 SHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRG-GFGPGKMDSRGEHRQD 520

Query: 552 SRQ 554
            R+
Sbjct: 521 RRE 523



 Score = 92.0 bits (227), Expect = 7e-18
 Identities = 87/263 (33%), Positives = 109/263 (41%), Gaps = 37/263 (14%)

Query: 2574 SSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHG 2633
            +  +G + +  GQ   YSQ  S       YGQ  S SG S   +  G    S S YGQ  
Sbjct: 11   TQSYGAYPTQPGQG--YSQQSS-----QPYGQQ-SYSGYSQSTDTSGYGQSSYSSYGQS- 61

Query: 2634 SGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGR------SSSRGPYESR 2687
                Q++G+G Q +  G   S G +GS     SS+GQ  S  G       SS+ G Y S 
Sbjct: 62   ----QNTGYGTQSTPQGYG-STGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSS 116

Query: 2688 LGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS-----GQSSTFDQEGSSTGQ 2742
               SS +GQ +SGS     YSQ  S  G   S GQ  S +     GQ + ++      G 
Sbjct: 117  -SQSSSYGQPQSGS-----YSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGG 170

Query: 2743 SSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHG 2802
                G+ G   S  S  G  G G G      +  SG G S  YGQ   G G+  G S  G
Sbjct: 171  GGGGGNYGQDQSSMSSGGGSGGGYG-----NQDQSGGGGSGGYGQQDRG-GRGRGGSGGG 224

Query: 2803 SGSGQDGYSYCKGGSNHDGGSSG 2825
             G G  GY+   GG    G   G
Sbjct: 225  GGGGGGGYNRSSGGYEPRGRGGG 247



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 97/311 (31%), Positives = 128/311 (41%), Gaps = 49/311 (15%)

Query: 2522 SSGYGRQGSGS-GQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 2580
            S+ Y +Q + S G  P    +G   + S  YG+  S SG S S+        ++SG+G  
Sbjct: 3    SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQ-SYSGYSQST--------DTSGYGQ- 52

Query: 2581 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS 2640
                   SSYS +G     ++GYG   +  G  S G  +GSS  S S YGQ  S      
Sbjct: 53   -------SSYSSYGQSQ--NTGYGTQSTPQGYGSTGG-YGSSQSSQSSYGQQSS----YP 98

Query: 2641 GHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHES- 2699
            G+G+Q + S  S   G +GS    SSS+GQ  SGS    S+ P  S  G    +GQ +S 
Sbjct: 99   GYGQQPAPSSTS---GSYGSS-SQSSSYGQPQSGS---YSQQP--SYGGQQQSYGQQQSY 149

Query: 2700 ----GSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTG---QSSSYGHRGSG 2752
                G G  + Y+    G G     G +G      S+    G   G   QS   G  G G
Sbjct: 150  NPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYG 209

Query: 2753 SSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSY 2812
                 G GR G+G G     G +   SG    Y   G G G+       G   G D   +
Sbjct: 210  QQDRGGRGRGGSGGGGGGGGGGYNRSSG---GYEPRGRGGGRGG----RGGMGGSDRGGF 262

Query: 2813 CKGGSNHDGGS 2823
             K G   D GS
Sbjct: 263  NKFGGPRDQGS 273



 Score = 89.7 bits (221), Expect = 4e-17
 Identities = 101/326 (30%), Positives = 125/326 (38%), Gaps = 51/326 (15%)

Query: 2514 QHGSGSSQSSG--YGRQGSGSGQSPGHGQRGSGSRQSPSYGR-HGSGSGRSSSSGQHGSG 2570
            Q G G SQ S   YG+Q S SG S      G G     SYG+   +G G  S+      G
Sbjct: 20   QPGQGYSQQSSQPYGQQ-SYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTP----QG 74

Query: 2571 LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYG 2630
             G + G+G  +SS    SSY       G  S Y  +G +   SS    +GSSS SSS YG
Sbjct: 75   YGSTGGYGSSQSSQ---SSY-------GQQSSYPGYGQQPAPSSTSGSYGSSSQSSS-YG 123

Query: 2631 QHGSGSRQSSGHGRQGSGSGQSPSRGRHGS-----GLGHSSSHGQHGSGSGRSSSRGPYE 2685
            Q  SGS     + +Q S  GQ  S G+  S     G G  + +     G G     G Y 
Sbjct: 124  QPQSGS-----YSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNY- 177

Query: 2686 SRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQH-GSTSGQSSTFDQEGSSTGQSS 2744
                          G   SS  S  GSG G + +Q Q  G  SG     D+ G   G S 
Sbjct: 178  --------------GQDQSSMSSGGGSGGG-YGNQDQSGGGGSGGYGQQDRGGRGRGGSG 222

Query: 2745 SYGHRGSG--SSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHG 2802
              G  G G  +  S GY   G G G+    GR G G      + + G    Q S +    
Sbjct: 223  GGGGGGGGGYNRSSGGYEPRGRGGGRG---GRGGMGGSDRGGFNKFGGPRDQGSRHDSEQ 279

Query: 2803 SGSGQDGYSYCKGGSNHDGGSSGSYF 2828
              S  +       G N    S   YF
Sbjct: 280  DNSDNNTIFVQGLGENVTIESVADYF 305



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 47/140 (33%), Positives = 56/140 (40%), Gaps = 14/140 (10%)

Query: 2708 SQHGSGSGHFCSQ--GQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAG 2765
            +Q G G     SQ  GQ  S SG S + D  G      SSYG      SQ++GYG     
Sbjct: 19   TQPGQGYSQQSSQPYGQQ-SYSGYSQSTDTSGYGQSSYSSYGQ-----SQNTGYGTQSTP 72

Query: 2766 SGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDG-YSYCKGGSNHDGGSS 2824
             G   S G +GS     SSYGQ  S      GY Q  + S   G Y      S++    S
Sbjct: 73   QGYG-STGGYGSSQSSQSSYGQQSS----YPGYGQQPAPSSTSGSYGSSSQSSSYGQPQS 127

Query: 2825 GSYFLSFPSSTSPYEYVQEQ 2844
            GSY            Y Q+Q
Sbjct: 128  GSYSQQPSYGGQQQSYGQQQ 147


>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
          Length = 592

 Score =  133 bits (334), Expect = 3e-30
 Identities = 159/602 (26%), Positives = 208/602 (34%), Gaps = 73/602 (12%)

Query: 1530 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 1589
            S  YGQ G      ST+G  GS     +S    G      SS+GQ+ SG S    YG+  
Sbjct: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSS---YGQSQ 60

Query: 1590 SGSGQSPG--HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS 1647
            SG  QS G    Q+ S   Q P Y   G      SS  Q G            + S  Q 
Sbjct: 61   SGYSQSYGGYENQKQSSYSQQP-YNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQ 119

Query: 1648 SSYSQHGSGSGHSSGYGQHG---SRSGQSSRGERHGSSS------RSSSRYGQ--HGSGS 1696
            S Y QH       S Y Q     S++ QS   +R   S       R  SRYG+   G G 
Sbjct: 120  SGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGG 179

Query: 1697 RQSSGHGRQG-SGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF- 1754
             Q  G GR G    G+ P  G  G   G   + G H     R+ +    ++ S ++++F 
Sbjct: 180  SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDN-SDNNTIFV 238

Query: 1755 ------------GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS-TFDQEGSSTG 1801
                        G+     G      + G    +  +    G   G+++ +FD   S+  
Sbjct: 239  QGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKA 298

Query: 1802 QSS-SHGQHGSGSSQSSSYG------QQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGW 1854
                  G+   G+    S+        +G GSG     GR G G G+    G  G G   
Sbjct: 299  AIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGG----GRRGRG-GYRGRGGFQGRGGDP 353

Query: 1855 SSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHG 1914
             S      + S  +  F    S +  +    +    SG       +G   G   RG + G
Sbjct: 354  KSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGG 413

Query: 1915 SSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY-----GPYGS 1969
               G        G G  +S G G  G  SG      R   G G  +   Y     G YG 
Sbjct: 414  DRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGG 473

Query: 1970 --GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSS 2027
              G G+   RG Y    G   G G R    G   GYG  G   G+    G +G    +  
Sbjct: 474  DRGGGYGGDRGGYGGDRGGGYG-GDRGGYGGDRGGYG--GDRGGYGGDRGGYGGDRSRGG 530

Query: 2028 SCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSG 2087
              G  G  SG          G  +S GYG   SG G     G RG G      YG    G
Sbjct: 531  YGGDRGGGSGY---------GGDRSGGYGGDRSGGGYG---GDRGGG------YGGDRGG 572

Query: 2088 SG 2089
             G
Sbjct: 573  YG 574



 Score =  126 bits (317), Expect = 3e-28
 Identities = 155/612 (25%), Positives = 212/612 (34%), Gaps = 75/612 (12%)

Query: 710  SSGYSQHGSGSSHSSGYRKHGSRS-GQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQ 768
            S  Y Q G      S Y   GS+  GQ+S+S   G      SSYGQ+ SG    S +G+ 
Sbjct: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYS-GYGQTTDSSYGQNYSGY---SSYGQS 59

Query: 769  GSGSGHSPSRVRHGSSSGHSSS-HGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQG 827
             SG   S     +   S +S   +   G   +  SS     S  G+A  + Q + G    
Sbjct: 60   QSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESS----GSQGGRAPSYDQPDYGQQDS 115

Query: 828  YSQHGSASGHFSSQGRHGSTSGQSSSSGQHDS-SSGQSSSYGQHESASHHAS-------- 878
            Y Q      H       GS   QS+   QHDS S  Q S + Q E+ SHH          
Sbjct: 116  YDQQSGYDQH------QGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSR 169

Query: 879  -GRGRHGSGSGQSPGHGQRG-SGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKS 936
             G    G G  Q  G G+ G    G+ P  G  G   G   + G H     ++       
Sbjct: 170  YGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESD 229

Query: 937  SSGQSSGYTQHGSGSGHSSS-----YEQHG-----SRSGQSS----RSEQHGSSSGSSSS 982
            +S  ++ + Q G G G S+      ++Q G      ++G+        +  G   G ++ 
Sbjct: 230  NSDNNTIFVQ-GLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATV 288

Query: 983  YGQHGSGSRQSLG-------HGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSS 1035
                   ++ ++        HG     S  +  P   R G   G     G YR   G+  
Sbjct: 289  SFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQG 348

Query: 1036 SRGPYESG-------SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSS 1088
              G  +SG       S  +     R S +  +    +    SG       +G   G    
Sbjct: 349  RGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGR 408

Query: 1089 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 1148
             G+ G   G        G G  +SSG G  G  SG   G G R  G       G +G   
Sbjct: 409  GGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG-GDRSGGGYGGDRGGGYGGDR 467

Query: 1149 GRSSSSGQHGSGLGESSGFGHHESS--SGQSSSY-SQHGSGSGHSSGY-GQHGSRSGQSS 1204
            G      + G   G+  G+G        G    Y    G   G   GY G  G   G  S
Sbjct: 468  GGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRS 527

Query: 1205 RGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSG 1264
            RG   G   G S      G G  +S G+G   SG G+    G  G G G     G  G  
Sbjct: 528  RGGYGGDRGGGS------GYGGDRSGGYGGDRSGGGYG---GDRGGGYG-----GDRGGY 573

Query: 1265 SGRSSSRGPYES 1276
             G+   R  Y +
Sbjct: 574  GGKMGGRNDYRN 585



 Score =  126 bits (317), Expect = 3e-28
 Identities = 165/607 (27%), Positives = 206/607 (33%), Gaps = 83/607 (13%)

Query: 1060 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 1119
            S  YGQ G      ST+G  GS     +S    G      SS+GQ+ SG S    YG+  
Sbjct: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSS---YGQSQ 60

Query: 1120 SGSGQSPG--HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS 1177
            SG  QS G    Q+ S   Q P Y   G      SS  Q G            + S  Q 
Sbjct: 61   SGYSQSYGGYENQKQSSYSQQP-YNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQ 119

Query: 1178 SSYSQHGSGSGHSSGYGQHG---SRSGQSSRGERHGSSSGSS------SHYGQ--HGSGS 1226
            S Y QH       S Y Q     S++ QS   +R   S  +       S YG+   G G 
Sbjct: 120  SGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGG 179

Query: 1227 RQSSGHGRQG-SGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFG 1285
             Q  G GR G    G  P  G  G   G   + G H     R+ +    ++ S ++++F 
Sbjct: 180  SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDN-SDNNTIFV 238

Query: 1286 QHESGSGHSSAYSQHG---SGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS-SYGHRGS 1341
            Q   G G   +  Q G      G   +  + G       T    G   G+++ S+    S
Sbjct: 239  Q---GLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPS 295

Query: 1342 GSSQ---SSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQS 1398
              +      G   HG     S +  R     G  S  G+ G G G+    G  G G    
Sbjct: 296  AKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRG-GYRGRGGFQGRGGDPK 354

Query: 1399 SG-------------FGHHESSSW---------QSSGCTQHGSGSGHSSSYEQHGSRSGQ 1436
            SG             F    S +          + SG    G G G    Y   G R G 
Sbjct: 355  SGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGD 414

Query: 1437 SS--RGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY 1494
                 G+R G   G   S G   SG R   G+G   SG G       G  G G G     
Sbjct: 415  RGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYG-----GDRGGGYGGDRG- 468

Query: 1495 SPYGS--GSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGST 1552
              YG   G G+   RG Y        G G R    G   GYG  G   G+    G +G  
Sbjct: 469  GGYGGDRGGGYGGDRGGYGGDRGGGYG-GDRGGYGGDRGGYG--GDRGGYGGDRGGYGGD 525

Query: 1553 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG 1612
              +    G  G  SG          G  +S GYG   SG G     G RG G      YG
Sbjct: 526  RSRGGYGGDRGGGSGY---------GGDRSGGYGGDRSGGGYG---GDRGGG------YG 567

Query: 1613 RHGSGSG 1619
                G G
Sbjct: 568  GDRGGYG 574



 Score =  125 bits (314), Expect = 6e-28
 Identities = 159/602 (26%), Positives = 213/602 (35%), Gaps = 56/602 (9%)

Query: 2000 SSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 2059
            S  YGQ G      ST+G  GS     +S    G      SS+GQ+ SG S    YG+  
Sbjct: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSS---YGQSQ 60

Query: 2060 SGSGQSPG--HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQS 2117
            SG  QS G    Q+ S   Q P Y   G      SS  Q G            + S  Q 
Sbjct: 61   SGYSQSYGGYENQKQSSYSQQP-YNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQ 119

Query: 2118 SSYSQHGSGSGHSSGYGQHG---SRSGQSSRGERHGSSSGSS------SRYGQ--HGSGS 2166
            S Y QH       S Y Q     S++ QS   +R   S  +       SRYG+   G G 
Sbjct: 120  SGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGG 179

Query: 2167 RQSSGHGRQG-SGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFG 2225
             Q  G GR G    G  P  G  G   G   + G H     R+ +    ++ S ++++F 
Sbjct: 180  SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDN-SDNNTIFV 238

Query: 2226 QHESGSGHSSAYSQHGS---GSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSG 2282
            Q   G G   +  Q G      G   +  + G       T    G   G+++        
Sbjct: 239  Q---GLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPS 295

Query: 2283 SSQSSSY--GQQGSGS--GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQS 2338
            +  +  +  G++  G+    S +  R     G  S  G+ G G G+    G  G G    
Sbjct: 296  AKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRG-GYRGRGGFQGRGGDPK 354

Query: 2339 SGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGS 2398
            SG     + S  +  + +  S +  +    +    SG   RG  +G   G     G+   
Sbjct: 355  SGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGR--G 412

Query: 2399 GSRQSLGHGQHGSGSGQSPSPSRG----RHGSGSGQSSSYSPYGS--GSGWSSSRGPYES 2452
            G R   G  + G G G   S   G    R G G G   S   YG   G G+   RG    
Sbjct: 413  GDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRG---G 469

Query: 2453 GSGHSSGLGHRESRSGQSS--GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSS 2510
            G G   G G+   R G     G G  G   G+    G +G   G     G      G   
Sbjct: 470  GYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG---GDRGGYGGDRGGYGGDR 526

Query: 2511 SHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSG 2570
            S G +G      SGYG   SG     G+G    G R    YG    G G     G +G  
Sbjct: 527  SRGGYGGDRGGGSGYGGDRSG-----GYG----GDRSGGGYG-GDRGGGYGGDRGGYGGK 576

Query: 2571 LG 2572
            +G
Sbjct: 577  MG 578



 Score =  124 bits (311), Expect = 1e-27
 Identities = 162/608 (26%), Positives = 213/608 (35%), Gaps = 104/608 (17%)

Query: 2092 SSSGQHGPGLGES---SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 2148
            S SG +G   GE    S +G+  S     +S S  G G    S YGQ+   SG SS G+ 
Sbjct: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQN--YSGYSSYGQ- 58

Query: 2149 HGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRS 2208
              S SG S  YG +    +QSS   +  +  G   +    GS  G + S+ Q   G   S
Sbjct: 59   --SQSGYSQSYGGY-ENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDS 115

Query: 2209 SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGS 2268
                 Y+ +SG+    G ++  S +   +  +      + SQ ++ S   Q    D   S
Sbjct: 116  -----YDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDV--S 168

Query: 2269 STGQSSSHGQHGSGSSQSSSYGQQG-SGSGQSPSRGRHGSGSGHSSSYGQH---GSGSGW 2324
              G+ +     G G SQ    G+ G    G+ P  G  G   G   ++G H   G  +  
Sbjct: 169  RYGEDN----RGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDA 224

Query: 2325 SSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHG-------SGSGHSSSY---------- 2367
             S S    + +    G G   S+      + Q G       +G    + Y          
Sbjct: 225  DSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKG 284

Query: 2368 ----------------------EQHGS--------RSGQSSRGERHGSSSGSSSSYGQHG 2397
                                  E HG+        R  +  RG   GS  G     G  G
Sbjct: 285  EATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGG--GSGGGRRGRGGYRG 342

Query: 2398 SGSRQSLGHGQHGSGSGQSPSPSRGRHG----SGSGQSSSYSPYGSGSGWSSSRGPYESG 2453
             G  Q  G G   SG    P+PS G       +   Q +   P  S       RG    G
Sbjct: 343  RGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRG---RG 398

Query: 2454 SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHG 2513
             G   G   R  R G   GYG   S  G+       G  SG  S  G  G  SG      
Sbjct: 399  YGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG------ 452

Query: 2514 QHGSGSSQSSGY-GRQGSGSGQSPGHG----QRGSGSRQSPSYG--RHGSGSGRSSSSGQ 2566
              G G  +  GY G +G G G   G G    + G G  +   YG  R G G  R    G 
Sbjct: 453  -GGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGD 511

Query: 2567 HGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH----SSGYGQHGSRSGQSSRGERHGSS 2622
             G   G+  G+G   S  G        G GSG+    S GYG  G RSG    G+R G  
Sbjct: 512  RGGYGGDRGGYGGDRSRGGYG---GDRGGGSGYGGDRSGGYG--GDRSGGGYGGDRGGGY 566

Query: 2623 SGSSSHYG 2630
             G    YG
Sbjct: 567  GGDRGGYG 574



 Score =  120 bits (301), Expect = 2e-26
 Identities = 150/587 (25%), Positives = 190/587 (32%), Gaps = 72/587 (12%)

Query: 223 SGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSS 282
           SGS   SG  Q   S+  + G   +G  S   SGYGQ    +  SS G+ +       SS
Sbjct: 4   SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQ----TTDSSYGQNY----SGYSS 55

Query: 283 YGQHGSGSRQSLG-HGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESG 341
           YGQ  SG  QS G +  Q   S     +   G      SS  Q G   SY       +  
Sbjct: 56  YGQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDS 115

Query: 342 SGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYG 401
             Q SG+ QH+    + S Y +       S SQ Q    S + + S       R  S YG
Sbjct: 116 YDQQSGYDQHQGSYDEQSNYDQQHD----SYSQNQQSYHSQRENYSHHTQDDRRDVSRYG 171

Query: 402 QHESASRHSSGRGQHSSG---SGQSPGHGQRGSGSGQSPSSGQH---GTGFGRSSSSGPY 455
           +       S G G+   G    G+ P  G  G   G   + G H   G      S S   
Sbjct: 172 EDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNS 231

Query: 456 VSGSGYSSGFGHHESSSEHSSGYTQHG------------------SGSGHSSGHGQ---- 493
            + + +  G G   S+ +    + Q G                    +G   G       
Sbjct: 232 DNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFD 291

Query: 494 -----------------HGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLG--HSRHG 534
                            HG+    S    R     G  S  G+ G G  +  G    R G
Sbjct: 292 DPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGG 351

Query: 535 ---SGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES-GSGHSSGLGHQESR 590
              SG    P+PS G      R S +            S G +   G G   G   +  R
Sbjct: 352 DPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGR 411

Query: 591 SGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYG 650
            G   GYG   S  G+       G  SG  S  G  G  SG    +G    G     R G
Sbjct: 412 GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG--GGYGGDRGGGYGGDRGG 469

Query: 651 QQGS--GSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSG 708
             G   G G    RG +G D G      + G G       G  G   G   G+G     G
Sbjct: 470 GYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRG 529

Query: 709 QSSGYSQHGS--GSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYG 753
              G    GS  G   S GY   G RSG     ++ G   G    YG
Sbjct: 530 GYGGDRGGGSGYGGDRSGGY--GGDRSGGGYGGDRGGGYGGDRGGYG 574



 Score =  119 bits (299), Expect = 3e-26
 Identities = 167/644 (25%), Positives = 218/644 (33%), Gaps = 111/644 (17%)

Query: 968  SRSEQHGSSSGSSSSYGQHGSGSRQSLGHG-QHGSGSGQSPSPSRGRHGSG--------S 1018
            S S  +G S G   SY  +G+   Q  G   Q  SG GQ+   S G++ SG        S
Sbjct: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQS 61

Query: 1019 GQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ--HGSSSGHSSTH 1076
            G S SYG Y +    S S+ PY +  G    +    S+ G++  Y Q  +G    +    
Sbjct: 62   GYSQSYGGYENQKQSSYSQQPYNN-QGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQS 120

Query: 1077 G--QH-GSTSGQSSSCGQHGA-SSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 1132
            G  QH GS   QS+   QH + S  Q S H Q  + S  +    R  S  G+      RG
Sbjct: 121  GYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGED----NRG 176

Query: 1133 SGSRQSPSYGRHG-SGSGRSSSSGQHGSGLGESSGFGHH-----------ESSSGQSSSY 1180
             G  Q    GR G    GR   +G  G   G    FG H           ES +  +++ 
Sbjct: 177  YGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTI 236

Query: 1181 SQHGSGSGHSSGY-GQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS 1239
               G G G S+   G+   + G     ++ G      + Y    +G  +    G      
Sbjct: 237  FVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPM--INLYTDKDTGKPK----GEATVSF 290

Query: 1240 GHSPSRGRHGSGLGHSSSHGQ----------------HGSGSGRSSSRGPYESRSGHSSV 1283
               PS             HG                  GSG GR   RG Y  R G    
Sbjct: 291  DDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRG-RGGYRGRGGFQGR 349

Query: 1284 FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGS 1343
             G  +SG            G+ +F    +  S +  +    ++   +G          G 
Sbjct: 350  GGDPKSGDW---VCPNPSCGNMNFA---RRNSCNQCNEPRPEDSRPSG----------GD 393

Query: 1344 SQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGH 1403
             +  GYG      G+   RGR G G G    YG   SG G+       G  SG  SG G+
Sbjct: 394  FRGRGYG------GERGYRGRGGRG-GDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGY 446

Query: 1404 HESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQS 1463
                     G  + G G G        G R G    G+R G   G    YG         
Sbjct: 447  ---------GGDRSGGGYGGDRGGGYGGDRGG-GYGGDRGGGYGGDRGGYG--------- 487

Query: 1464 LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHR 1523
               G  G G G       G  G   G    Y     G G   SRG Y  G     G G+ 
Sbjct: 488  ---GDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGY--GGDRGGGSGYG 542

Query: 1524 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSG 1567
              RSG   GYG   S  G+    G      G     G +G   G
Sbjct: 543  GDRSG---GYGGDRSGGGYGGDRG-----GGYGGDRGGYGGKMG 578



 Score =  117 bits (294), Expect = 1e-25
 Identities = 163/609 (26%), Positives = 208/609 (34%), Gaps = 106/609 (17%)

Query: 1622 SSSGQHGSGLGES---SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1678
            S SG +G   GE    S +G+  S     +S S  G G    S YGQ+   SG SS G+ 
Sbjct: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQN--YSGYSSYGQS 59

Query: 1679 HGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRS 1738
                S+S   Y       +QSS   +  +  GQ  +    GS  G + S+ Q   G   S
Sbjct: 60   QSGYSQSYGGY----ENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDS 115

Query: 1739 SSRGPYESRSGHSSVFGQHESGSGHSSAY-SQHGSGSGHFCSQGQHGSTSGQSSTFDQEG 1797
                 Y+ +SG+     QH+      S Y  QH S S    +Q  + S     S   Q+ 
Sbjct: 116  -----YDQQSGYD----QHQGSYDEQSNYDQQHDSYSQ---NQQSYHSQRENYSHHTQDD 163

Query: 1798 SSTGQSSSHGQHGSGSSQSSSYGQQG-SGSGQSPSRGRHGSGSGHSSSYGQH---GSGSG 1853
                        G G SQ    G+ G    G+ P  G  G   G   ++G H   G  + 
Sbjct: 164  RRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTD 223

Query: 1854 WSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHG-------SGSGHSSSY--------- 1897
              S S    + +    G G   S+      + Q G       +G    + Y         
Sbjct: 224  ADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPK 283

Query: 1898 -----------------------EQHG--------SRSGQSSRGEQHGSSSGSSSSYGQH 1926
                                   E HG        +R  +  RG   GS  G     G  
Sbjct: 284  GEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRG--GGSGGGRRGRGGYR 341

Query: 1927 GSGSRQSLGHGQHGSGSGQSPSPSRGR----HGSGSGQSSSYGPYGSGSGWSSSRGPYES 1982
            G G  Q  G G   SG    P+PS G       +   Q +   P  S       RG    
Sbjct: 342  GRGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRG---R 397

Query: 1983 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSH 2042
            G G   G   R  R G   GYG   S  G+       G  SG  S  G  G  SG     
Sbjct: 398  GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG----- 452

Query: 2043 GQHGSGSSQSSGY-GRQGSGSGQSPGHG----QRGSGSRQSPSYG--RHGSGSGRSSSSG 2095
               G G  +  GY G +G G G   G G    + G G  +   YG  R G G  R    G
Sbjct: 453  --GGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGG 510

Query: 2096 QHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGH----SSGYGQHGSRSGQSSRGERHGS 2151
              G   G+  G+G   S  G        G GSG+    S GYG  G RSG    G+R G 
Sbjct: 511  DRGGYGGDRGGYGGDRSRGGYG---GDRGGGSGYGGDRSGGYG--GDRSGGGYGGDRGGG 565

Query: 2152 SSGSSSRYG 2160
              G    YG
Sbjct: 566  YGGDRGGYG 574



 Score =  116 bits (291), Expect = 3e-25
 Identities = 151/628 (24%), Positives = 218/628 (34%), Gaps = 82/628 (13%)

Query: 802  SSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTS-GQSSS--SGQHD 858
            S  G Y    G+   +  + +   QGY   G AS  +S  G+   +S GQ+ S  S    
Sbjct: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGY---GQASQSYSGYGQTTDSSYGQNYSGYSSYGQ 58

Query: 859  SSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSS 918
            S SG S SYG +E+    +  +  + +  GQ       GS  G++PSY +          
Sbjct: 59   SQSGYSQSYGGYENQKQSSYSQQPYNN-QGQQQNMESSGSQGGRAPSYDQ---------- 107

Query: 919  SGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSG 978
                         +G + S  Q SGY QH       S+Y+Q        S S+   S   
Sbjct: 108  -----------PDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQ-----HDSYSQNQQSYHS 151

Query: 979  SSSSYGQHGSGSRQSLG-HGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSR 1037
               +Y  H    R+ +  +G+   G G S    RGR   G       GP    SG    R
Sbjct: 152  QRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGR---GGYDKDGRGPMTGSSG--GDR 206

Query: 1038 GPYESGSGHSSGLGHRESRSGQS----------SGYGQHGSSSGHSSTHGQHG-----ST 1082
            G +++  GH    G R     +S           G G+  S+        Q G       
Sbjct: 207  GGFKNFGGHRD-YGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKK 265

Query: 1083 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG 1142
            +G+          +G+             S+          +  G+  + S + + P + 
Sbjct: 266  TGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFM 325

Query: 1143 R-HGSGSGRSSSSGQHGSGLGESSGFGHHESS-------SGQSSSYSQHGSGSGHSSGYG 1194
            R  GSG GR    G  G G  +  G G  +S        S  + ++++  S +  +    
Sbjct: 326  RGGGSGGGRRGRGGYRGRGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRP 384

Query: 1195 QHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGH 1254
            +    SG   RG  +G   G     G+   G R   G  R G G G   S G   SG   
Sbjct: 385  EDSRPSGGDFRGRGYGGERGYRGRGGR--GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRS 442

Query: 1255 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHG 1314
               +G   SG G    RG      G+       + G G+         G G+   +G +G
Sbjct: 443  GGGYGGDRSGGGYGGDRG-----GGYGG-----DRGGGYGG-----DRGGGYGGDRGGYG 487

Query: 1315 STSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSS 1374
               G     D+ G    +    G RG       GYG   +  G    RG  GSG G   S
Sbjct: 488  GDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRG-GGSGYGGDRS 546

Query: 1375 YGQHGSGSGWSSSSGRHGSGSGQSSGFG 1402
             G  G  SG      R G   G   G+G
Sbjct: 547  GGYGGDRSGGGYGGDRGGGYGGDRGGYG 574



 Score =  116 bits (290), Expect = 4e-25
 Identities = 162/642 (25%), Positives = 208/642 (32%), Gaps = 117/642 (18%)

Query: 1443 HGSSSGSSSSYGQHGSGSRQSLGHG-QHGSGSGQSPSPSRGRHGSGSGQSSSYSPYG-SG 1500
            +G S G   SY  +G+   Q  G   Q  SG GQ+   S G++ SG      YS YG S 
Sbjct: 7    YGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSG------YSSYGQSQ 60

Query: 1501 SGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH-----GQHGSTSGQ 1555
            SG+S S G YE+    SS      +  GQ       GS  G + ++     GQ  S   Q
Sbjct: 61   SGYSQSYGGYEN-QKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQ 119

Query: 1556 SSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP----------GHGQRGSGS 1605
            S      G+   QS+   QH S S     Y  Q                  G   RG G 
Sbjct: 120  SGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGG 179

Query: 1606 RQSPSYGRHG-SGSGRSSSSGQHGSGLGESSGFGHH-----------ESSSGQSSSYSQH 1653
             Q    GR G    GR   +G  G   G    FG H           ES +  +++    
Sbjct: 180  SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQ 239

Query: 1654 GSGSGHSSGY-GQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQS 1712
            G G G S+   G+   + G     ++ G      + Y    +G  +    G         
Sbjct: 240  GLGEGVSTDQVGEFFKQIGIIKTNKKTGKPM--INLYTDKDTGKPK----GEATVSFDDP 293

Query: 1713 PSRGRHGSGLGHSSSHGQ----------------HGSGSGRSSSRGPYESRSGHSSVFGQ 1756
            PS             HG                  GSG GR   RG Y  R G     G 
Sbjct: 294  PSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRG-RGGYRGRGGFQGRGGD 352

Query: 1757 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTS-GQSSTFDQEGSSTGQSSSHGQHGSGSSQ 1815
             +SG                 C     G+ +  + ++ +Q      + S   +   G  +
Sbjct: 353  PKSGDW--------------VCPNPSCGNMNFARRNSCNQCNEPRPEDS---RPSGGDFR 395

Query: 1816 SSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHE 1875
               YG      G+   RGR G G G    YG   SG G+       G  SG  SG G+  
Sbjct: 396  GRGYG------GERGYRGRGGRG-GDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGY-- 446

Query: 1876 SSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLG 1935
                   G  + G G G        G R G    G++ G   G    YG           
Sbjct: 447  -------GGDRSGGGYGGDRGGGYGGDRGG-GYGGDRGGGYGGDRGGYG----------- 487

Query: 1936 HGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRES 1995
             G  G G G       G  G   G    YG    G G   SRG Y    G  SG G    
Sbjct: 488  -GDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG---- 542

Query: 1996 RSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSG 2037
               +S GYG   S  G+    G      G     G +G   G
Sbjct: 543  -GDRSGGYGGDRSGGGYGGDRG-----GGYGGDRGGYGGKMG 578



 Score =  115 bits (289), Expect = 5e-25
 Identities = 159/605 (26%), Positives = 212/605 (35%), Gaps = 72/605 (11%)

Query: 124 ESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQN 183
           ++S S+S +    + SY +N  G    G        S+    + + +SYS Q   Y  Q 
Sbjct: 30  QASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYENQKQSSYSQQP--YNNQG 87

Query: 184 SDSHQSSGRGQCGSG-SGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKS-SSGQS 241
              +  S   Q G   S   P+YGQ  S   QS  +   GS   QS+   QH S S  Q 
Sbjct: 88  QQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQ 147

Query: 242 SGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGS 301
           S +SQ  + S H+    +  SR G+ +RG            YG    G R   G+ + G 
Sbjct: 148 SYHSQRENYSHHTQDDRRDVSRYGEDNRG------------YGGSQGGGRGRGGYDKDGR 195

Query: 302 GSRQSPSHVRHGSGSGHSSSHGQHG------SGSSYSYSRGHYESGSGQ---TSGFGQHE 352
           G     S    G G  +   H  +G      S S  S +   +  G G+   T   G+  
Sbjct: 196 GPMTGSSGGDRG-GFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFF 254

Query: 353 SGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQ----HESASR 408
              G      K G    +  +    G   G+A+ S     S++ +  +      H +  +
Sbjct: 255 KQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIK 314

Query: 409 HSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHH 468
            S    +     G   G G+RG G G     G  G G    S      + S  +  F   
Sbjct: 315 VSFATRRPEFMRGGGSGGGRRGRG-GYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARR 373

Query: 469 ESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSL 528
            S ++ +    +    SG       +G   G   RG R G   G    YG    G R   
Sbjct: 374 NSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGG----YG----GDR--- 422

Query: 529 GHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQE 588
                 SG G     S G   SG R    YG    G G    RG    G G   G G+  
Sbjct: 423 ------SGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRG---GGYGGDRGGGYGG 473

Query: 589 SRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSR 648
            R G   GYG  G   G+    G  G   G     G  G   G    +G    G      
Sbjct: 474 DRGG---GYG--GDRGGYG---GDRGGGYG-----GDRGGYGGDRGGYGGDRGG------ 514

Query: 649 YGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGS-GWSSSNGPHGSVSGQSSGFGHKSGS 707
           YG    G G   SRG +G D G  S YG   SG  G   S G +G   G   G G + G 
Sbjct: 515 YGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYG-GDRGGY 573

Query: 708 GQSSG 712
           G   G
Sbjct: 574 GGKMG 578



 Score =  115 bits (288), Expect = 6e-25
 Identities = 155/595 (26%), Positives = 211/595 (35%), Gaps = 57/595 (9%)

Query: 176 SSSYGEQNSDSHQSSGRGQCGS-GSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQH 234
           S SYG+   +    S  G  GS G GQ+    Q  SG GQ++ +    + SG SS + Q 
Sbjct: 4   SGSYGQSGGEQQSYSTYGNPGSQGYGQA---SQSYSGYGQTTDSSYGQNYSGYSS-YGQS 59

Query: 235 KSSSGQS-SGYSQHGSGSGHSSGYGQHGSRSGQSSRGERH-RSSSGSSSSYGQHGSGSRQ 292
           +S   QS  GY      S     Y   G +    S G +  R+ S     YGQ  S  +Q
Sbjct: 60  QSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQ 119

Query: 293 SLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHE 352
           S     QGS   QS    +H S S +  S+  H    +YS+   H +      S +G+  
Sbjct: 120 SGYDQHQGSYDEQSNYDQQHDSYSQNQQSY--HSQRENYSH---HTQDDRRDVSRYGEDN 174

Query: 353 SGSGQSSG-------YSKHGSGSGHSSSQGQHGSTS--------GQASSSGQHGSSSRQS 397
            G G S G       Y K G G    SS G  G           G  + +     +S  +
Sbjct: 175 RGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNN 234

Query: 398 SSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSS---GP 454
           + + Q       +   G+     G    + + G       +    G   G ++ S    P
Sbjct: 235 TIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPP 294

Query: 455 YVSGS-GYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGS 513
               +  +  G   H +  + S    +     G  SG G+ G R G   RG  QG     
Sbjct: 295 SAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRG-RGGYRGRGGFQGRGGDP 353

Query: 514 SSSYGQHGSGSRQSLGHSRHGS-GSGQSPSPSRGRHESGSRQSSSYG-PHGYGS--GRSS 569
            S      + S  ++  +R  S      P P   R   G  +   YG   GY    GR  
Sbjct: 354 KSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGG 413

Query: 570 SRGPY---ESGSGH----SSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQ-HGSTSGQSS 621
            RG Y    SG G+    SSG G+   RSG   GYG   S  G+    G  +G   G   
Sbjct: 414 DRGGYGGDRSGGGYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGGDRGGGYGGDRGGGY 471

Query: 622 SCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFG-------HSSS 674
              + G   G    +G    G     R G  G   G    RG +G D G           
Sbjct: 472 GGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGY 531

Query: 675 YGQHGSGSGWSS--SNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYR 727
            G  G GSG+    S G  G  SG   G+G   G G       +G      + YR
Sbjct: 532 GGDRGGGSGYGGDRSGGYGGDRSG--GGYGGDRGGGYGGDRGGYGGKMGGRNDYR 584



 Score =  115 bits (287), Expect = 8e-25
 Identities = 149/596 (25%), Positives = 206/596 (34%), Gaps = 67/596 (11%)

Query: 2151 SSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSS 2210
            S SGS   YGQ G   +  S +G  GS      S+   G G    SS+GQ+ SG    SS
Sbjct: 2    SDSGS---YGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGY---SS 55

Query: 2211 RGPYESRSGHSSVFGQHESGSGHSSAYSQHG-SGSGHFCSQGQHGSTSGQSSTFDQ---- 2265
             G  +S+SG+S  +G +E+     S+YSQ   +  G   +    GS  G++ ++DQ    
Sbjct: 56   YG--QSQSGYSQSYGGYENQK--QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYG 111

Query: 2266 EGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHS----------SSY 2315
            +  S  Q S + QH     + S+Y QQ     Q+  +  H     +S          S Y
Sbjct: 112  QQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQN-QQSYHSQRENYSHHTQDDRRDVSRY 170

Query: 2316 GQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSG 2375
            G+   G G S   GR G G     G G    SS    G  ++  G           S S 
Sbjct: 171  GEDNRGYGGSQGGGR-GRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESD 229

Query: 2376 QSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQS-----PSPSRGRHGSGSGQ 2430
             S          G   S  Q G   +Q +G  +    +G+           G+    +  
Sbjct: 230  NSDNNTIFVQGLGEGVSTDQVGEFFKQ-IGIIKTNKKTGKPMINLYTDKDTGKPKGEATV 288

Query: 2431 SSSYSPYGSGS----------------GWSSSRGPYESGSGHSSGLGHRESRSGQSSGYG 2474
            S    P    +                 +++ R  +  G G   G   R    G+    G
Sbjct: 289  SFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQG 348

Query: 2475 QHGSSSG------HSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 2528
            + G          + S    + +     + C +      + S     G G     GY  +
Sbjct: 349  RGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGR 408

Query: 2529 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSS 2588
            G   G   G+G    G R    YG   S  G  S     G   G+ SG G+     G   
Sbjct: 409  GGRGGDRGGYG----GDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYG 464

Query: 2589 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHY-GQHGSGSRQSSGHGRQGS 2647
                 G G     GYG  G R G    G+R G   G    Y G  G       G+G    
Sbjct: 465  GDRGGGYGGDRGGGYG--GDRGGYG--GDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRG 520

Query: 2648 GSGQSPSRGRHGSGLGHSSSHGQHGSGS-GRSSSRGPYESRLGHSSVFGQHESGSG 2702
            G G   SRG +G   G  S +G   SG  G   S G Y    G    +G    G G
Sbjct: 521  GYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGG--YGGDRGGYG 574



 Score =  110 bits (276), Expect = 2e-23
 Identities = 161/610 (26%), Positives = 220/610 (36%), Gaps = 67/610 (10%)

Query: 1152 SSSGQHGSGLGES---SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1208
            S SG +G   GE    S +G+  S     +S S  G G    S YGQ+   SG SS G+ 
Sbjct: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQN--YSGYSSYGQ- 58

Query: 1209 HGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRS 1268
              S SG S  YG +    +QSS   +  +  G   +    GS  G + S+ Q   G   S
Sbjct: 59   --SQSGYSQSYGGY-ENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDS 115

Query: 1269 SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGS 1328
                 Y+ +SG+    G ++  S +   +  +      + SQ ++ S   Q    D    
Sbjct: 116  -----YDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDV--- 167

Query: 1329 STGQSSSYG--HRGSGSSQSSGYGRHGAGS-GQSPSRGRHGSGSGHSSSYGQH---GSGS 1382
                 S YG  +RG G SQ  G GR G    G+ P  G  G   G   ++G H   G  +
Sbjct: 168  -----SRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRT 222

Query: 1383 GWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGER 1442
               S S    + +    G G   S+        Q G    +  + +   +       G+ 
Sbjct: 223  DADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKP 282

Query: 1443 HGSSSGSSSSYGQHGSGSRQSLGHGQHG-----SGSGQSPSPSRGRHGSGSGQSSSYSPY 1497
             G ++ S        +      G   HG     S + + P   RG  GSG G+       
Sbjct: 283  KGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGG-GSGGGRR------ 335

Query: 1498 GSGSGWSSSRGPYES-GSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 1556
              G G    RG ++  G    SG     + S  +  + +  S +  +    +    SG  
Sbjct: 336  --GRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGD 393

Query: 1557 SSCGQHGASSGQSSSHGQHGSGSSQSSGYG--RQGSGSGQSPGHGQRGSGSRQSPSYGRH 1614
                 +G   G+    G+ G G  +  GYG  R G G G     G   SG R    YG  
Sbjct: 394  FRGRGYG---GERGYRGRGGRGGDRG-GYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGD 449

Query: 1615 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 1674
             SG G     G  G G G   G G+     G        G G G   GYG  G R G   
Sbjct: 450  RSGGGYG---GDRGGGYGGDRGGGYGGDRGG--------GYG-GDRGGYG--GDRGG-GY 494

Query: 1675 RGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHG-- 1732
             G+R G         G  G       G+G   S  G    RG  GSG G   S G  G  
Sbjct: 495  GGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRG-GGSGYGGDRSGGYGGDR 553

Query: 1733 SGSGRSSSRG 1742
            SG G    RG
Sbjct: 554  SGGGYGGDRG 563



 Score =  110 bits (275), Expect = 2e-23
 Identities = 161/616 (26%), Positives = 216/616 (35%), Gaps = 85/616 (13%)

Query: 2249 SQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSG 2308
            S GQ G      ST+   GS     +S    G G +  SSYGQ  SG     S G+  S 
Sbjct: 6    SYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYS---SYGQ--SQ 60

Query: 2309 SGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHS---- 2364
            SG+S SYG +      SS S +  +  GQ        S   ++  Y Q   G   S    
Sbjct: 61   SGYSQSYGGY-ENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQ 119

Query: 2365 SSYEQH-GSRSGQSSRGERHGSSSGSSSSY-------GQHGSGSRQSLG-HGQHGSGSGQ 2415
            S Y+QH GS   QS+  ++H S S +  SY         H    R+ +  +G+   G G 
Sbjct: 120  SGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGG 179

Query: 2416 SPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSS---- 2471
            S    RGR   G        P    SG    RG +++  GH    G R     +S     
Sbjct: 180  SQGGGRGR---GGYDKDGRGPMTGSSG--GDRGGFKNFGGHRD-YGPRTDADSESDNSDN 233

Query: 2472 ------GYGQHGSSSGHSSTHGQHG-----STSGQSSSCGQHGASSGQSSSHGQHGSGSS 2520
                  G G+  S+        Q G       +G+          +G+            
Sbjct: 234  NTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDP 293

Query: 2521 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHG-SGSGRSSSSGQHGSGLGESSGFGH 2579
             S+          +  G+  + S + + P + R G SG GR    G  G G  +  G G 
Sbjct: 294  PSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRG-GD 352

Query: 2580 HESS-------SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQH 2632
             +S        S  + ++++  S +  +    +    SG   RG  +G   G     G+ 
Sbjct: 353  PKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGR- 411

Query: 2633 GSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSS 2692
              G R   G  R G G G   S G   SG      +G   SG G    RG      G+  
Sbjct: 412  -GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGG-----GYGG 465

Query: 2693 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYG-HRGS 2751
                 + G G+       G G G     G  G   G     D+ G   G    YG  RG 
Sbjct: 466  -----DRGGGYGG---DRGGGYG-----GDRGGYGG-----DRGGGYGGDRGGYGGDRGG 507

Query: 2752 GSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYS 2811
                  GYG    G G   S G +G   G  S YG   SG     GY    SG    GY 
Sbjct: 508  YGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSG-----GYGGDRSGG---GYG 559

Query: 2812 YCKGGSNHDGGSSGSY 2827
              +GG    GG  G Y
Sbjct: 560  GDRGGGY--GGDRGGY 573



 Score =  106 bits (265), Expect = 3e-22
 Identities = 151/615 (24%), Positives = 198/615 (32%), Gaps = 67/615 (10%)

Query: 2234 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQG 2293
            S +Y Q G     + + G  GS     ++    G      SS+GQ+ SG S   SYGQ  
Sbjct: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYS---SYGQSQ 60

Query: 2294 SGSGQSPSRGRHGSGSGHSSS-YGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 2352
            SG  QS     +   S +S   Y   G      SS  + G            + S  Q S
Sbjct: 61   SGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQS 120

Query: 2353 GYTQHGSGSGHSSSYEQHG---SRSGQSSRGERHGSSSGSS------SSYGQ--HGSGSR 2401
            GY QH       S+Y+Q     S++ QS   +R   S  +       S YG+   G G  
Sbjct: 121  GYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGS 180

Query: 2402 QSLGHGQHG---SGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSS 2458
            Q  G G+ G    G G     S G  G G      +  YG  +   S     ++ +    
Sbjct: 181  QGGGRGRGGYDKDGRGPMTGSSGGDRG-GFKNFGGHRDYGPRTDADSESDNSDNNTIFVQ 239

Query: 2459 GLGHRESRSGQSSGYGQHGSSSGHSST---------HGQHGSTSGQSSSCGQHGASSGQS 2509
            GLG   S       + Q G    +  T             G   G+++       S+  +
Sbjct: 240  GLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAA 299

Query: 2510 ----SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSG 2565
                     HG+    S    R     G   G G+RG G  +    G  G G    S   
Sbjct: 300  IDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRG-GFQGRGGDPKSGDW 358

Query: 2566 QHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGS 2625
               +    +  F    S +  +    +    SG       +G   G   RG R G   G 
Sbjct: 359  VCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGY 418

Query: 2626 SSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGS-GSGRSSSRGPY 2684
                   G G  +SSG G  G  SG      R G G G     G  G  G G    RG  
Sbjct: 419  GGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRG-- 476

Query: 2685 ESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS 2744
                     +G    G G        G   G+   +G +G            G   G   
Sbjct: 477  -------GGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGG---------DRGGYGGDRG 520

Query: 2745 SYGHRGSGSSQSSGYGR-HGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGS 2803
             YG    G     GYG   G GSG          G  +S  YG   SG G   G    G 
Sbjct: 521  GYG----GDRSRGGYGGDRGGGSGY---------GGDRSGGYGGDRSGGGY-GGDRGGGY 566

Query: 2804 GSGQDGYSYCKGGSN 2818
            G  + GY    GG N
Sbjct: 567  GGDRGGYGGKMGGRN 581



 Score =  106 bits (264), Expect = 4e-22
 Identities = 158/629 (25%), Positives = 210/629 (33%), Gaps = 100/629 (15%)

Query: 1755 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSS 1814
            G +    G   +YS +G+       Q    S SG   T D   SS GQ+ S G    G S
Sbjct: 5    GSYGQSGGEQQSYSTYGNPGSQGYGQASQ-SYSGYGQTTD---SSYGQNYS-GYSSYGQS 59

Query: 1815 QS--------------SSYGQQG-SGSGQSPSRGRHGSGSGHSSSYGQ--HGSGSGWSSS 1857
            QS              SSY QQ  +  GQ  +    GS  G + SY Q  +G    +   
Sbjct: 60   QSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQ 119

Query: 1858 SG---RHGSGSGQSSGFGHHES-SSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQH 1913
            SG     GS   QS+    H+S S  Q S ++Q  + S H+    +  SR G+ +RG   
Sbjct: 120  SGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRG--- 176

Query: 1914 GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYG---PYGSG 1970
                     YG    G R   G+ + G G      P  G  G   G   ++G    YG  
Sbjct: 177  ---------YGGSQGGGRGRGGYDKDGRG------PMTGSSGGDRGGFKNFGGHRDYGPR 221

Query: 1971 SGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS---------THGQHGS 2021
            +   S     ++ +    GLG   S       + Q G    +           T    G 
Sbjct: 222  TDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGK 281

Query: 2022 ASGQSSSCGQHGASSGQS----SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ 2077
              G+++       S+  +         HG+    S    R     G   G G+RG G  +
Sbjct: 282  PKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYR 341

Query: 2078 SPSYGRHG-SGSGRSSSSGQ---HGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGY 2133
                GR G  G G    SG      P  G +  F    S +  +    +    SG     
Sbjct: 342  ----GRGGFQGRGGDPKSGDWVCPNPSCG-NMNFARRNSCNQCNEPRPEDSRPSGGDFRG 396

Query: 2134 GQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSG 2193
              +G   G   RG R G   G        G G  +SSG G  G  SG      R G G G
Sbjct: 397  RGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYG 456

Query: 2194 HSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQH 2253
                 G  G G G     G    R G    +G    G G        G   G+   +G +
Sbjct: 457  -----GDRGGGYGGDRGGGYGGDRGGG---YGGDRGGYGGDRGGGYGGDRGGYGGDRGGY 508

Query: 2254 GSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSS 2313
            G   G            G     G +G   S+    G +G GSG          G   S 
Sbjct: 509  GGDRG------------GYGGDRGGYGGDRSRGGYGGDRGGGSGY---------GGDRSG 547

Query: 2314 SYGQHGSGSGWSSSSGRHGSGSGQSSGFG 2342
             YG   SG G+    G  G   G   G+G
Sbjct: 548  GYGGDRSGGGYGGDRG--GGYGGDRGGYG 574



 Score =  105 bits (262), Expect = 6e-22
 Identities = 154/641 (24%), Positives = 227/641 (35%), Gaps = 88/641 (13%)

Query: 312 HGSGSGHSSSHGQHGSGSSYSYSRGHYE-SGSGQTSGFGQHESGSGQS-SGYSKHG-SGS 368
           +G   G   S+  +G+  S  Y +     SG GQT+     +S  GQ+ SGYS +G S S
Sbjct: 7   YGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTT-----DSSYGQNYSGYSSYGQSQS 61

Query: 369 GHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQ 428
           G+S S G +           Q  SS  Q     Q +  +  SSG     + S   P +GQ
Sbjct: 62  GYSQSYGGY---------ENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQ 112

Query: 429 RGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGY-TQHGSGSGH 487
           + S   QS          G     G Y   S Y      H+S S++   Y +Q  + S H
Sbjct: 113 QDSYDQQS----------GYDQHQGSYDEQSNYDQ---QHDSYSQNQQSYHSQRENYSHH 159

Query: 488 SSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGR 547
           +    +  SR G+ +RG            YG    G R   G+ + G G     + S G 
Sbjct: 160 TQDDRRDVSRYGEDNRG------------YGGSQGGGRGRGGYDKDGRGP---MTGSSGG 204

Query: 548 HESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHS 607
              G +    +  +G  +   S     ++ +    GLG   S    +   G+     G  
Sbjct: 205 DRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVS----TDQVGEFFKQIGII 260

Query: 608 STHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRY--GQQGSGSGQSPSRGRH 665
            T+ + G       +    G   G+++        +  +  +  G++  G+    S    
Sbjct: 261 KTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATR 320

Query: 666 GSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSG-------SGQSSGYSQHGS 718
             +F         GSG G     G  G    Q  G   KSG       S  +  +++  S
Sbjct: 321 RPEFMRGG-----GSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNS 375

Query: 719 GSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSR 778
            +  +    +    SG   R   +G   G     G+ G       G+G   SG G+   R
Sbjct: 376 CNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGD----RGGYGGDRSGGGYGGDR 431

Query: 779 VRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHF 838
              G  SG  S  G  G       S G Y  G  +  G+G  + G G G  + G   G+ 
Sbjct: 432 SSGGGYSGDRSGGGYGGD-----RSGGGY--GGDRGGGYGG-DRGGGYGGDRGG---GYG 480

Query: 839 SSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGS 898
             +G +G   G     G      G    YG       +   RG +G    +    G RG 
Sbjct: 481 GDRGGYGGDRG-GGYGGDRGGYGGDRGGYGGDRGG--YGGDRGGYGGDRSRGGYGGDRGG 537

Query: 899 GSG----QSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHK 935
           GSG    +S  YG   SG G     G  G   G   G+G K
Sbjct: 538 GSGYGGDRSGGYGGDRSGGGYGGDRG--GGYGGDRGGYGGK 576



 Score =  103 bits (257), Expect = 2e-21
 Identities = 150/619 (24%), Positives = 206/619 (33%), Gaps = 65/619 (10%)

Query: 385 SSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGT 444
           S SG +G S  +  SY  + +    S G GQ S          Q  SG GQ+  S  +G 
Sbjct: 2   SDSGSYGQSGGEQQSYSTYGNPG--SQGYGQAS----------QSYSGYGQTTDSS-YGQ 48

Query: 445 GFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSG---YTQHGSGSGHSSGHGQHGSRSGQS 501
            +   SS G   S SGYS  +G +E+  + S     Y   G      S   Q G      
Sbjct: 49  NYSGYSSYGQ--SQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYD 106

Query: 502 SRGERQGSSAGSSSSYGQH-GSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGP 560
                Q  S    S Y QH GS   QS    +H S S           +S   Q  +Y  
Sbjct: 107 QPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYS--------QNQQSYHSQRENYSH 158

Query: 561 HGYGSGRSSSR-GPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQ 619
           H     R  SR G    G G S G G          GY       G     G  G   G 
Sbjct: 159 HTQDDRRDVSRYGEDNRGYGGSQGGGRGR------GGY----DKDGRGPMTGSSGGDRGG 208

Query: 620 SSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSR-GRHGSDFGHSSSYGQH 678
             + G H     ++ +  +  S +S ++    QG G G S  + G      G   +  + 
Sbjct: 209 FKNFGGHRDYGPRTDADSE--SDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKT 266

Query: 679 GSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSR 738
           G       ++   G   G+++       S +++             G   HG+    S  
Sbjct: 267 GKPMINLYTDKDTGKPKGEATVSFDDPPSAKAA--------IDWFDGKEFHGNIIKVSFA 318

Query: 739 SEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGT 798
           + +     G  S  G+ G G ++  G G QG G           + S  + +  +  S  
Sbjct: 319 TRRPEFMRGGGSGGGRRGRGGYRGRG-GFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCN 377

Query: 799 SCSSSCGHYESGSG---QASGFGQHESGSGQ--------GYSQHGSASGHFSSQGRHGST 847
            C+         SG   +  G+G      G+        GY    S  G+   +   G  
Sbjct: 378 QCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGY 437

Query: 848 SGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYG 907
           SG  S  G     SG    YG      +     G +G   G   G  + G G  +   YG
Sbjct: 438 SGDRSGGGYGGDRSG--GGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYG 495

Query: 908 --RHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSG 965
             R G G  R    G  G   G   G+G   S G   G    GSG G   S    G RSG
Sbjct: 496 GDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSG 555

Query: 966 QSSRSEQHGSSSGSSSSYG 984
                ++ G   G    YG
Sbjct: 556 GGYGGDRGGGYGGDRGGYG 574



 Score =  103 bits (256), Expect = 3e-21
 Identities = 144/609 (23%), Positives = 190/609 (31%), Gaps = 60/609 (9%)

Query: 1285 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQE-GSSTGQSSSYGHRGSGS 1343
            G +    G   +YS +G+       Q    S SG   T D   G +    SSYG   SG 
Sbjct: 5    GSYGQSGGEQQSYSTYGNPGSQGYGQASQ-SYSGYGQTTDSSYGQNYSGYSSYGQSQSGY 63

Query: 1344 SQS-SGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFG 1402
            SQS  GY      S         G      SS  Q G    +            Q SG+ 
Sbjct: 64   SQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYD 123

Query: 1403 HHESS-SWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQ--HGSG 1459
             H+ S   QS+   QH S S +  SY          ++ +R        S YG+   G G
Sbjct: 124  QHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRR-----DVSRYGEDNRGYG 178

Query: 1460 SRQSLGHGQHG---SGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSH 1516
              Q  G G+ G    G G     S G  G G      +  YG  +   S     ++ +  
Sbjct: 179  GSQGGGRGRGGYDKDGRGPMTGSSGGDRG-GFKNFGGHRDYGPRTDADSESDNSDNNTIF 237

Query: 1517 SSGLGHRESRSGQSSGYGQHGSSSGHSS---------THGQHGSTSGQSSSCGQHGASSG 1567
              GLG   S       + Q G    +           T    G   G+++       S+ 
Sbjct: 238  VQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAK 297

Query: 1568 QS----SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSS 1623
             +         HG+    S    R     G   G G+RG G  +    G  G G    S 
Sbjct: 298  AAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRG-GFQGRGGDPKSG 356

Query: 1624 SGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSS 1683
                 +    +  F    S +  +    +    SG       +G   G   RG R G   
Sbjct: 357  DWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRG 416

Query: 1684 RSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGP 1743
                     G G  +SSG G  G  SG      R G G G     G  G G G     G 
Sbjct: 417  GYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYG-----GDRGGGYGGDRGGGY 471

Query: 1744 YESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQS 1803
               R G    +G    G G        G   G+   +G +G   G            G  
Sbjct: 472  GGDRGGG---YGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRG------------GYG 516

Query: 1804 SSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS 1863
               G +G   S+    G +G GSG          G   S  YG   SG G+    G  G 
Sbjct: 517  GDRGGYGGDRSRGGYGGDRGGGSGY---------GGDRSGGYGGDRSGGGYGGDRG--GG 565

Query: 1864 GSGQSSGFG 1872
              G   G+G
Sbjct: 566  YGGDRGGYG 574



 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 129/522 (24%), Positives = 178/522 (34%), Gaps = 61/522 (11%)

Query: 106 HQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDF 165
           +Q Q++  E+   +  R  S   +     G+ DSY +      + G +        Q ++
Sbjct: 85  NQGQQQNMESSGSQGGRAPS---YDQPDYGQQDSYDQ------QSGYDQHQGSYDEQSNY 135

Query: 166 SGQHNSYSGQSSSYGEQNSD-SHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSG 224
             QH+SYS    SY  Q  + SH +    +  S  G+  N G  GS  G          G
Sbjct: 136 DQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGED-NRGYGGSQGGGRGRGGYDKDG 194

Query: 225 SGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHR---SSSGSSS 281
            G  +G     SS G   G+   G   GH   YG       +S   + +       G   
Sbjct: 195 RGPMTG-----SSGGDRGGFKNFG---GHRD-YGPRTDADSESDNSDNNTIFVQGLGEGV 245

Query: 282 SYGQHGSGSRQ-SLGHGRQGSG----SRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRG 336
           S  Q G   +Q  +    + +G    +  +        G    S      + ++  +  G
Sbjct: 246 STDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDG 305

Query: 337 HYESGSGQTSGFG----QHESGSGQSSGYSKHGSGSGHSSSQGQHGS-TSGQ---ASSSG 388
               G+     F     +   G G   G    G   G    QG+ G   SG     + S 
Sbjct: 306 KEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSC 365

Query: 389 QHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSG----QHGT 444
            + + +R++S    +E     S   G    G G     G RG G       G    + G 
Sbjct: 366 GNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGG 425

Query: 445 GFGRSSSSGPYVSGSGYSSGFGHHES----SSEHSSGY-TQHGSGSGHSSGHGQHGSRSG 499
           G+G   SSG   SG     G+G   S      +   GY    G G G   G G  G R G
Sbjct: 426 GYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGG 485

Query: 500 QSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSG---SGQSPSPSRGRHESGSRQSS 556
               G+R G   G    YG    G R   G  R G G    G     SRG +  G R   
Sbjct: 486 YG--GDRGGGYGGDRGGYG----GDRGGYGGDRGGYGGDRGGYGGDRSRGGY-GGDRGGG 538

Query: 557 SYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYG 598
           S    GYG  RS   G   SG G+    G      G   GYG
Sbjct: 539 S----GYGGDRSGGYGGDRSGGGYGGDRG--GGYGGDRGGYG 574



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 118/507 (23%), Positives = 154/507 (30%), Gaps = 66/507 (13%)

Query: 93  YCQVSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDS-YSRNVRGSLKPG 151
           Y Q  GS      +  Q +     ++    Q  ++SH +     + S Y  + RG    G
Sbjct: 122 YDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGY--GG 179

Query: 152 TESISR-RLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSG-RGQCGSGSGQSPNYGQHG 209
           ++   R R  + +D  G     SG     G +N   H+  G R    S S  S N     
Sbjct: 180 SQGGGRGRGGYDKDGRGPMTGSSGGDRG-GFKNFGGHRDYGPRTDADSESDNSDNNTIFV 238

Query: 210 SGSGQSSSNDTHGSGSGQSSGFSQHKSS------------SGQSSGYSQHGSGSGHSS-- 255
            G G+  S D  G    Q      +K +            +G+  G +        S+  
Sbjct: 239 QGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKA 298

Query: 256 ------GYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSH 309
                 G   HG+    S    R     G  S  G+ G G  +  G G QG G       
Sbjct: 299 AIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRG-GFQGRGGDPKSGD 357

Query: 310 VRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSG 369
               + S  + +  +  S +  +  R      SG          G  +  GY       G
Sbjct: 358 WVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSG----------GDFRGRGYGGERGYRG 407

Query: 370 HSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQR 429
                G  G   G  S  G  G  S      G   S  R   G G   SG G     G R
Sbjct: 408 RGGRGGDRGGYGGDRSGGGYGGDRSS-----GGGYSGDRSGGGYGGDRSGGGYG---GDR 459

Query: 430 GSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSS 489
           G G G     G  G G+G     G      GY    G          G  + G G     
Sbjct: 460 GGGYG-----GDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGG 514

Query: 490 GHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHE 549
             G  G   G  SRG   G   G  S YG   SG     G  R G G G           
Sbjct: 515 YGGDRGGYGGDRSRG-GYGGDRGGGSGYGGDRSG---GYGGDRSGGGYG----------- 559

Query: 550 SGSRQSSSYGPHGYGSGRSSSRGPYES 576
            G R     G  G   G+   R  Y +
Sbjct: 560 -GDRGGGYGGDRGGYGGKMGGRNDYRN 585



 Score = 64.7 bits (156), Expect = 1e-09
 Identities = 67/216 (31%), Positives = 96/216 (44%), Gaps = 24/216 (11%)

Query: 2621 SSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSS 2680
            S SGS   YGQ G   +  S +G  GS      S+   G G    SS+GQ+ SG    SS
Sbjct: 2    SDSGS---YGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSG---YSS 55

Query: 2681 RGPYESRLGHSSVFGQHESGSGHSSAYSQHG-SGSGHFCSQGQHGSTSGQSSTFDQ---- 2735
             G  +S+ G+S  +G +E+     S+YSQ   +  G   +    GS  G++ ++DQ    
Sbjct: 56   YG--QSQSGYSQSYGGYENQK--QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYG 111

Query: 2736 EGSSTGQSSSYG-HRGSGSSQSSGYGRHGAGS-GQSLSHGRHGSGSGQS-------SSYG 2786
            +  S  Q S Y  H+GS   QS+   +H + S  Q   H +  + S  +       S YG
Sbjct: 112  QQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYG 171

Query: 2787 QHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGG 2822
            +   G G S G  +   G  +DG     G S  D G
Sbjct: 172  EDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRG 207



 Score = 63.9 bits (154), Expect = 2e-09
 Identities = 76/256 (29%), Positives = 101/256 (39%), Gaps = 35/256 (13%)

Query: 2562 SSSGQHGSGLGES---SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 2618
            S SG +G   GE    S +G+  S     +S S  G G    S YGQ+   SG SS G+ 
Sbjct: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQN--YSGYSSYGQ- 58

Query: 2619 HGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRS 2678
              S SG S  YG +    +QSS   +  +  GQ  +    GS  G + S+ Q   G   S
Sbjct: 59   --SQSGYSQSYGGY-ENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDS 115

Query: 2679 SSRGPYESRLGHSSVFGQHESGSGHSSAY-SQHGSGSGHFCSQGQHGSTSGQSSTFDQEG 2737
                 Y+ + G+     QH+      S Y  QH S      SQ Q    S + +      
Sbjct: 116  -----YDQQSGYD----QHQGSYDEQSNYDQQHDS-----YSQNQQSYHSQRENYSHHTQ 161

Query: 2738 SSTGQSSSYG--HRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQS 2795
                  S YG  +RG G SQ  G GR G        + + G G    SS G  G G    
Sbjct: 162  DDRRDVSRYGEDNRGYGGSQGGGRGRGG--------YDKDGRGPMTGSSGGDRG-GFKNF 212

Query: 2796 SGYSQHGSGSGQDGYS 2811
             G+  +G  +  D  S
Sbjct: 213  GGHRDYGPRTDADSES 228



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 36/114 (31%), Positives = 49/114 (42%), Gaps = 4/114 (3%)

Query: 2730 SSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHG 2789
            S ++ Q G      S+YG+ GS     +     G G     S+G++ SG    SSYGQ  
Sbjct: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGY---SSYGQSQ 60

Query: 2790 SGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGSYFLSFPSSTSPYEYVQE 2843
            SG  QS G  ++   S      Y   G   +  SSGS     PS   P +Y Q+
Sbjct: 61   SGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQP-DYGQQ 113



 Score = 43.1 bits (100), Expect = 0.004
 Identities = 47/159 (29%), Positives = 60/159 (37%), Gaps = 14/159 (8%)

Query: 2695 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSS 2754
            G +    G   +YS +G+       Q    S SG   T D   SS GQ+ S G+   G S
Sbjct: 5    GSYGQSGGEQQSYSTYGNPGSQGYGQASQ-SYSGYGQTTD---SSYGQNYS-GYSSYGQS 59

Query: 2755 QSSGYGRHGAG---SGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYS 2811
            Q SGY +   G     QS    +  +  GQ  +    GS  G++  Y Q   G  QD Y 
Sbjct: 60   Q-SGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQ-QDSYD 117

Query: 2812 YCKGGSNHDGGSSGSYFLSFPSSTSPYEYVQEQRCYFYQ 2850
               G   H     GSY            Y Q Q+ Y  Q
Sbjct: 118  QQSGYDQH----QGSYDEQSNYDQQHDSYSQNQQSYHSQ 152


>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
          Length = 589

 Score =  128 bits (321), Expect = 9e-29
 Identities = 157/600 (26%), Positives = 211/600 (35%), Gaps = 72/600 (12%)

Query: 1530 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSG-SSQSSGYGRQ 1588
            S  YGQ G      ST+G  GS     +S    G      SS+GQ+ SG SS    Y + 
Sbjct: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQS 63

Query: 1589 GSG---SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGES----SGFGHHE 1641
              G     QS    Q  +   Q  +    GS  GR+ S  Q   G  +S    SG+  H+
Sbjct: 64   YGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQ 123

Query: 1642 SSSGQSSSYSQ-HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQ--HGSGSRQ 1698
             S  + S+Y Q H S S +   Y  H  R   S   +      R  SRYG+   G G  Q
Sbjct: 124  GSYDEQSNYDQQHDSYSQNQQSY--HSQRENYSHHTQ---DDRRDVSRYGEDNRGYGGSQ 178

Query: 1699 SSGHGRQG-SGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF--- 1754
              G GR G    G+ P  G  G   G   + G H     R+ +    ++ S ++++F   
Sbjct: 179  GGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDN-SDNNTIFVQG 237

Query: 1755 ----------GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS-TFDQEGSSTGQS 1803
                      G+     G      + G    +  +    G   G+++ +FD   S+    
Sbjct: 238  LGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAI 297

Query: 1804 S-SHGQHGSGSSQSSSYG------QQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS 1856
                G+   G+    S+        +G GSG     GR G G G+    G  G G    S
Sbjct: 298  DWFDGKEFHGNIIKVSFATRRPEFMRGGGSGG----GRRGRG-GYRGRGGFQGRGGDPKS 352

Query: 1857 SSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSS 1916
                  + S  +  F    S +  +    +    SG       +G   G   RG + G  
Sbjct: 353  GDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDR 412

Query: 1917 SGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY-----GPYGS-- 1969
             G        G G  +S G G  G  SG      R   G G  +   Y     G YG   
Sbjct: 413  GGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDR 472

Query: 1970 GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSC 2029
            G G+   RG Y    G   G G R    G   GYG  G   G+    G +G    +    
Sbjct: 473  GGGYGGDRGGYGGDRGGGYG-GDRGGYGGDRGGYG--GDRGGYGGDRGGYGGDRSRGGYG 529

Query: 2030 GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG 2089
            G  G  SG          G  +S GYG   SG G     G RG G      YG    G G
Sbjct: 530  GDRGGGSGY---------GGDRSGGYGGDRSGGGYG---GDRGGG------YGGDRGGYG 571



 Score =  122 bits (306), Expect = 5e-27
 Identities = 166/611 (27%), Positives = 214/611 (35%), Gaps = 62/611 (10%)

Query: 2039 SSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHG 2098
            S S+GQ G      S YG  GS           G G     SYG++ SG    SS GQ  
Sbjct: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGY---SSYGQ-- 58

Query: 2099 PGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSS-SGSSS 2157
                 S  +G +E+   + SSYSQ          Y   G +    S G + G + S    
Sbjct: 59   ---SYSQSYGGYENQ--KQSSYSQQP--------YNNQGQQQNMESSGSQGGRAPSYDQP 105

Query: 2158 RYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSS-HGQHGSGSGRSSSRGPYES 2216
             YGQ  S  +QS     QGS    S    +H S S +  S H Q  + S  +       S
Sbjct: 106  DYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVS 165

Query: 2217 RSGHSSV-FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 2275
            R G  +  +G  + G      Y + G G     S G  G         D  G  T   S 
Sbjct: 166  RYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDY-GPRTDADSE 224

Query: 2276 HGQHGSGSSQSSSYGQQGSGSGQSPSR-GRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 2334
                 S +S +++   QG G G S  + G      G   +  + G       +    G  
Sbjct: 225  -----SDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKP 279

Query: 2335 SGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYG 2394
             G+++       S+  +  +       G+        +R  +  RG   GS  G     G
Sbjct: 280  KGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVS-FATRRPEFMRGG--GSGGGRRGRGG 336

Query: 2395 QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG----SGSGQSSSYSPYGSGSGWSSSRGPY 2450
              G G  Q  G G   SG    P+PS G       +   Q +   P  S       RG  
Sbjct: 337  YRGRGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRG-- 393

Query: 2451 ESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSS 2510
              G G   G   R  R G   GYG   S  G+       G  SG  S  G  G  SG   
Sbjct: 394  -RGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG--- 449

Query: 2511 SHGQHGSGSSQSSGY-GRQGSGSGQSPGHG----QRGSGSRQSPSYG--RHGSGSGRSSS 2563
                 G G  +  GY G +G G G   G G    + G G  +   YG  R G G  R   
Sbjct: 450  ----GGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGY 505

Query: 2564 SGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH----SSGYGQHGSRSGQSSRGERH 2619
             G  G   G+  G+G   S  G        G GSG+    S GYG  G RSG    G+R 
Sbjct: 506  GGDRGGYGGDRGGYGGDRSRGGYG---GDRGGGSGYGGDRSGGYG--GDRSGGGYGGDRG 560

Query: 2620 GSSSGSSSHYG 2630
            G   G    YG
Sbjct: 561  GGYGGDRGGYG 571



 Score =  121 bits (304), Expect = 9e-27
 Identities = 143/591 (24%), Positives = 199/591 (33%), Gaps = 41/591 (6%)

Query: 594  SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQG 653
            S  YGQ G      ST+G  GS     +S    G      SS+GQ+ SG S   +   Q 
Sbjct: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQS 63

Query: 654  SGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGY 713
             G  ++  +  +     ++    Q+   SG      P    S     +G +    Q SGY
Sbjct: 64   YGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAP----SYDQPDYGQQDSYDQQSGY 119

Query: 714  SQHGSGSSHSSGY-RKHG--SRSGQSSRSEQHGSSSGLS------SSYGQ--HGSGSHQS 762
             QH       S Y ++H   S++ QS  S++   S          S YG+   G G  Q 
Sbjct: 120  DQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQG 179

Query: 763  SGHGRQG-SGSGHSPSRVRHGSSSGHSSSHGQH---GSGTSCSSSCGHYESGSGQASGFG 818
             G GR G    G  P     G   G   + G H   G  T   S   + ++ +    G G
Sbjct: 180  GGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLG 239

Query: 819  QHESGS--GQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHH 876
            +  S    G+ + Q G          +    +G+   +   D  +G+             
Sbjct: 240  EGVSTDQVGEFFKQIGII--------KTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPP 291

Query: 877  ASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGR-HGSGSGRSSSSGRHGSGSGQSSGFGHK 935
            ++          +  G+  + S + + P + R  GSG GR    G  G G  Q  G   K
Sbjct: 292  SAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPK 351

Query: 936  SSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR---SEQHGSSSGSSSSYGQHGSGSRQ 992
            S        +         +S  Q      + SR    +  G   G    Y   G     
Sbjct: 352  SGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGD 411

Query: 993  SLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGH 1052
              G+G   SG G     S G   SG      YG  RSG G+   RG    G G   G G+
Sbjct: 412  RGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRG---GGYGGDRGGGY 468

Query: 1053 RESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGAS-SGQSSSHGQHGSGSSQ 1111
               R G   GYG      G     G  G   G     G +G    G     G +G   S+
Sbjct: 469  GGDRGG---GYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSR 525

Query: 1112 SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLG 1162
                G +G GSG          G R    YG    G G     G +G  +G
Sbjct: 526  GGYGGDRGGGSGYGGDRSGGYGGDRSGGGYG-GDRGGGYGGDRGGYGGKMG 575



 Score =  121 bits (304), Expect = 9e-27
 Identities = 159/599 (26%), Positives = 205/599 (34%), Gaps = 119/599 (19%)

Query: 710  SSGYSQHGSGSSHSSGYRKHGSRS-GQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQ 768
            S  Y Q G      S Y   GS+  GQ+S+S   G      SSYGQ+ SG + S G    
Sbjct: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYS-GYGQTTDSSYGQNYSG-YSSYGQSYS 61

Query: 769  GSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGY 828
             S  G+   +     SS     +   G   +  SS     S  G+A  + Q + G    Y
Sbjct: 62   QSYGGYENQK----QSSYSQQPYNNQGQQQNMESS----GSQGGRAPSYDQPDYGQQDSY 113

Query: 829  SQHGSASGHFSSQGRHGSTSGQSSSSGQHDS-SSGQSSSYGQHESASHHAS--------- 878
             Q      H       GS   QS+   QHDS S  Q S + Q E+ SHH           
Sbjct: 114  DQQSGYDQH------QGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRY 167

Query: 879  -------------GRGRHG-SGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGS 924
                         GRGR G    G+ P  G  G   G   ++G H     R+ +     +
Sbjct: 168  GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDN 227

Query: 925  GSGQS---SGFGHKSSSGQSSGY--------TQHGSGSGHSSSY--EQHGSRSGQSSRS- 970
                +    G G   S+ Q   +        T   +G    + Y  +  G   G+++ S 
Sbjct: 228  SDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSF 287

Query: 971  ----------------EQHGS-------------SSGSSSSYGQHGSGSRQSLGHGQHGS 1001
                            E HG+               G  S  G+ G G  +  G  Q   
Sbjct: 288  DDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRG 347

Query: 1002 GSGQS-----PSPSRGRHG----SGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGH 1052
            G  +S     P+PS G       +   Q +   P  S       RG    G G   G   
Sbjct: 348  GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRG---RGYGGERGYRG 404

Query: 1053 RESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQS 1112
            R  R G   GYG   S  G+       G  SG  S  G  G  SG        G G  + 
Sbjct: 405  RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG-------GGYGGDRG 457

Query: 1113 SGY-GRQGSGSGQSPGHG----QRGSGSRQSPSYG--RHGSGSGRSSSSGQHGSGLGESS 1165
             GY G +G G G   G G    + G G  +   YG  R G G  R    G  G   G+  
Sbjct: 458  GGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRG 517

Query: 1166 GFGHHESSSGQSSSYSQHGSGSGH----SSGYGQHGSRSGQSSRGERHGSSSGSSSHYG 1220
            G+G   S  G        G GSG+    S GYG  G RSG    G+R G   G    YG
Sbjct: 518  GYGGDRSRGGYG---GDRGGGSGYGGDRSGGYG--GDRSGGGYGGDRGGGYGGDRGGYG 571



 Score =  119 bits (299), Expect = 3e-26
 Identities = 156/602 (25%), Positives = 209/602 (34%), Gaps = 59/602 (9%)

Query: 2000 SSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 2059
            S  YGQ G      ST+G  GS     +S    G      SS+GQ+       SGY   G
Sbjct: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQN------YSGYSSYG 57

Query: 2060 SGSGQSPG--HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQS 2117
                QS G    Q+ S   Q P Y   G      SS  Q G            + S  Q 
Sbjct: 58   QSYSQSYGGYENQKQSSYSQQP-YNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQ 116

Query: 2118 SSYSQHGSGSGHSSGYGQHG---SRSGQSSRGERHGSSSGSS------SRYGQ--HGSGS 2166
            S Y QH       S Y Q     S++ QS   +R   S  +       SRYG+   G G 
Sbjct: 117  SGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGG 176

Query: 2167 RQSSGHGRQG-SGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFG 2225
             Q  G GR G    G  P  G  G   G   + G H     R+ +    ++ S ++++F 
Sbjct: 177  SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDN-SDNNTIFV 235

Query: 2226 QHESGSGHSSAYSQHGS---GSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSG 2282
            Q   G G   +  Q G      G   +  + G       T    G   G+++        
Sbjct: 236  Q---GLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPS 292

Query: 2283 SSQSSSY--GQQGSGS--GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQS 2338
            +  +  +  G++  G+    S +  R     G  S  G+ G G G+    G  G G    
Sbjct: 293  AKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRG-GYRGRGGFQGRGGDPK 351

Query: 2339 SGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGS 2398
            SG     + S  +  + +  S +  +    +    SG   RG  +G   G     G+   
Sbjct: 352  SGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGR--G 409

Query: 2399 GSRQSLGHGQHGSGSGQSPSPSRG----RHGSGSGQSSSYSPYGS--GSGWSSSRGPYES 2452
            G R   G  + G G G   S   G    R G G G   S   YG   G G+   RG    
Sbjct: 410  GDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRG---G 466

Query: 2453 GSGHSSGLGHRESRSGQSS--GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSS 2510
            G G   G G+   R G     G G  G   G+    G +G   G     G      G   
Sbjct: 467  GYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG---GDRGGYGGDRGGYGGDR 523

Query: 2511 SHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSG 2570
            S G +G      SGYG   SG     G+G    G R    YG    G G     G +G  
Sbjct: 524  SRGGYGGDRGGGSGYGGDRSG-----GYG----GDRSGGGYG-GDRGGGYGGDRGGYGGK 573

Query: 2571 LG 2572
            +G
Sbjct: 574  MG 575



 Score =  119 bits (297), Expect = 6e-26
 Identities = 166/634 (26%), Positives = 216/634 (34%), Gaps = 122/634 (19%)

Query: 1152 SSSGQHGSGLGES---SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1208
            S SG +G   GE    S +G+  S     +S S  G G    S YGQ+   SG SS G+ 
Sbjct: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQN--YSGYSSYGQS 59

Query: 1209 HGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRS 1268
            +  S G   +        +QSS   +  +  G   +    GS  G + S+ Q   G   S
Sbjct: 60   YSQSYGGYEN-------QKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDS 112

Query: 1269 SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGS 1328
                 Y+ +SG+    G ++  S +   +  +      + SQ ++ S   Q    D    
Sbjct: 113  -----YDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDV--- 164

Query: 1329 STGQSSSYG--HRGSGSSQSSGYGRHGAGS-GQSPSRGRHGSGSGHSSSYGQH---GSGS 1382
                 S YG  +RG G SQ  G GR G    G+ P  G  G   G   ++G H   G  +
Sbjct: 165  -----SRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRT 219

Query: 1383 GWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHG-------SGSGHSSSY-------- 1427
               S S    + +    G G   S+        Q G       +G    + Y        
Sbjct: 220  DADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKP 279

Query: 1428 ------------------------EQHGS--------RSGQSSRGERHGSSSGSSSSYGQ 1455
                                    E HG+        R  +  RG   GS  G     G 
Sbjct: 280  KGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGG--GSGGGRRGRGGY 337

Query: 1456 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHG----SGSGQSSSYSPYGSGSGWSSSRGPYE 1511
             G G  Q  G G   SG    P+PS G       +   Q +   P  S       RG   
Sbjct: 338  RGRGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRG--- 393

Query: 1512 SGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSS 1571
             G     G   R  R G   GYG   S  G+       G  SG  S  G  G  SG    
Sbjct: 394  RGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG---- 449

Query: 1572 HGQHGSGSSQSSGY-GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSG 1630
                G G  +  GY G +G G G     G RG G      YG    G G     G  G G
Sbjct: 450  ---GGYGGDRGGGYGGDRGGGYG-----GDRGGG------YGGDRGGYG-----GDRGGG 490

Query: 1631 L-GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRY 1689
              G+  G+G      G        G   G   GYG   SR G    G+R G S     R 
Sbjct: 491  YGGDRGGYGGDRGGYG-----GDRGGYGGDRGGYGGDRSRGGYG--GDRGGGSGYGGDRS 543

Query: 1690 GQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLG 1723
            G +G G R   G+G    G G    RG +G  +G
Sbjct: 544  GGYG-GDRSGGGYGGD-RGGGYGGDRGGYGGKMG 575



 Score =  118 bits (296), Expect = 7e-26
 Identities = 154/601 (25%), Positives = 211/601 (35%), Gaps = 68/601 (11%)

Query: 167 GQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSG---SGQSSSNDTHGS 223
           G+  SYS    +YG   S  +  + +   G G     +YGQ+ SG    GQS S    G 
Sbjct: 12  GEQQSYS----TYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYGGY 67

Query: 224 GSGQSSGFSQHK-SSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSS 282
            + + S +SQ   ++ GQ       GS  G +  Y Q                       
Sbjct: 68  ENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQ---------------------PD 106

Query: 283 YGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSS-HGQHGSGSSYSYSRGHYESG 341
           YGQ  S  +QS     QGS   QS    +H S S +  S H Q  + S ++       S 
Sbjct: 107 YGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSR 166

Query: 342 SGQTS-GFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTS--------GQASSSGQHGS 392
            G+ + G+G  + G     GY K G G    SS G  G           G  + +     
Sbjct: 167 YGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESD 226

Query: 393 SSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSS 452
           +S  ++ + Q       +   G+     G    + + G       +    G   G ++ S
Sbjct: 227 NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVS 286

Query: 453 ---GPYVSGS-GYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQG 508
               P    +  +  G   H +  + S    +     G  SG G+ G R G   RG  QG
Sbjct: 287 FDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRG-RGGYRGRGGFQG 345

Query: 509 SSAGSSSSYGQHGSGSRQSLGHSRHGS-GSGQSPSPSRGRHESGSRQSSSY-GPHGY--G 564
                 S      + S  ++  +R  S      P P   R   G  +   Y G  GY   
Sbjct: 346 RGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGR 405

Query: 565 SGRSSSRGPY---ESGSGH----SSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTS 617
            GR   RG Y    SG G+    SSG G+   RSG   GYG   S  G+    G  G   
Sbjct: 406 GGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGGDRG--GGYG 461

Query: 618 GQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQ 677
           G     G +G   G      + G G  +   YG  G   G    RG +G D G    YG 
Sbjct: 462 GDRG--GGYGGDRGGGYGGDRGGYGGDRGGGYG--GDRGGYGGDRGGYGGDRG---GYGG 514

Query: 678 HGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSS 737
              G G   S G +G   G  SG+G     G     S  G G     GY   G R G   
Sbjct: 515 DRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGY--GGDRGGYGG 572

Query: 738 R 738
           +
Sbjct: 573 K 573



 Score =  116 bits (290), Expect = 4e-25
 Identities = 149/586 (25%), Positives = 191/586 (32%), Gaps = 73/586 (12%)

Query: 223 SGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSS 282
           SGS   SG  Q   S+  + G   +G  S   SGYGQ    +  SS G+ +       SS
Sbjct: 4   SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQ----TTDSSYGQNY----SGYSS 55

Query: 283 YGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGS 342
           YGQ  S S     + +Q S S+Q   +   G      SS  Q G   SY       +   
Sbjct: 56  YGQSYSQSYGGYENQKQSSYSQQ--PYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSY 113

Query: 343 GQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQ 402
            Q SG+ QH+    + S Y +       S SQ Q    S + + S       R  S YG+
Sbjct: 114 DQQSGYDQHQGSYDEQSNYDQQHD----SYSQNQQSYHSQRENYSHHTQDDRRDVSRYGE 169

Query: 403 HESASRHSSGRGQHSSG---SGQSPGHGQRGSGSGQSPSSGQH---GTGFGRSSSSGPYV 456
                  S G G+   G    G+ P  G  G   G   + G H   G      S S    
Sbjct: 170 DNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSD 229

Query: 457 SGSGYSSGFGHHESSSEHSSGYTQHG------------------SGSGHSSGHGQ----- 493
           + + +  G G   S+ +    + Q G                    +G   G        
Sbjct: 230 NNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDD 289

Query: 494 ----------------HGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLG--HSRHG- 534
                           HG+    S    R     G  S  G+ G G  +  G    R G 
Sbjct: 290 PPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGD 349

Query: 535 --SGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES-GSGHSSGLGHQESRS 591
             SG    P+PS G      R S +            S G +   G G   G   +  R 
Sbjct: 350 PKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRG 409

Query: 592 GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQ 651
           G   GYG   S  G+       G  SG  S  G  G  SG    +G    G     R G 
Sbjct: 410 GDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG--GGYGGDRGGGYGGDRGGG 467

Query: 652 QGS--GSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQ 709
            G   G G    RG +G D G      + G G       G  G   G   G+G     G 
Sbjct: 468 YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGG 527

Query: 710 SSGYSQHGS--GSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYG 753
             G    GS  G   S GY   G RSG     ++ G   G    YG
Sbjct: 528 YGGDRGGGSGYGGDRSGGY--GGDRSGGGYGGDRGGGYGGDRGGYG 571



 Score =  115 bits (289), Expect = 5e-25
 Identities = 153/597 (25%), Positives = 198/597 (33%), Gaps = 82/597 (13%)

Query: 968  SRSEQHGSSSGSSSSYGQHGSGSRQSLGHG-QHGSGSGQSPSPSRGRHGSG-----SGQS 1021
            S S  +G S G   SY  +G+   Q  G   Q  SG GQ+   S G++ SG        S
Sbjct: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYS 61

Query: 1022 SSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS 1081
             SYG Y +    S S+ PY +  G    +    S+ G++  Y Q          +GQ  S
Sbjct: 62   QSYGGYENQKQSSYSQQPYNN-QGQQQNMESSGSQGGRAPSYDQ--------PDYGQQDS 112

Query: 1082 TSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP----------GHGQR 1131
               QS      G+   QS+   QH S S     Y  Q                  G   R
Sbjct: 113  YDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNR 172

Query: 1132 GSGSRQSPSYGRHG-SGSGRSSSSGQHGSGLGESSGFGHH-----------ESSSGQSSS 1179
            G G  Q    GR G    GR   +G  G   G    FG H           ES +  +++
Sbjct: 173  GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNT 232

Query: 1180 YSQHGSGSGHSSG-YGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSG 1238
                G G G S+   G+   + G     ++ G      + Y    +G  +    G     
Sbjct: 233  IFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKP--MINLYTDKDTGKPK----GEATVS 286

Query: 1239 SGHSPSRGRHGSGLGHSSSHGQ----------------HGSGSGRSSSRGPYESRSGHSS 1282
                PS             HG                  GSG GR   RG Y  R G   
Sbjct: 287  FDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGR-RGRGGYRGRGGFQG 345

Query: 1283 VFGQHESGSG--HSSAYSQHGSGSGHFCSQ-GQHGSTSGQSSTFDQEGSSTGQSSSYGHR 1339
              G  +SG     + +         + C+Q  +      + S  D  G   G    Y  R
Sbjct: 346  RGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGR 405

Query: 1340 GSGSSQSSGYG--RHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQ 1397
            G       GYG  R G G G   S G   SG      YG   SG G+    G  G G  +
Sbjct: 406  GGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRG-GGYGGDR 464

Query: 1398 SSGFGHHESSSWQSSGCTQHGSGSGHSSSY--EQHGSRSGQSSRGERHGSSSGSSSSYGQ 1455
              G+G      +   G  + G G      Y  ++ G    +   G   G   G    YG 
Sbjct: 465  GGGYGGDRGGGY---GGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYG- 520

Query: 1456 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGS--GSGWSSSRGPY 1510
             G  SR   G G  G GSG     S G  G  SG       YG   G G+   RG Y
Sbjct: 521  -GDRSRGGYG-GDRGGGSGYGGDRSGGYGGDRSG-----GGYGGDRGGGYGGDRGGY 570



 Score =  115 bits (287), Expect = 8e-25
 Identities = 146/625 (23%), Positives = 212/625 (33%), Gaps = 79/625 (12%)

Query: 802  SSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSS 861
            S  G Y    G+   +  + +   QGY   G AS  +S  G+   +S   + SG      
Sbjct: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGY---GQASQSYSGYGQTTDSSYGQNYSGYSSYGQ 58

Query: 862  GQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGR 921
              S SYG +E+    +  +  + +  GQ       GS  G++PSY               
Sbjct: 59   SYSQSYGGYENQKQSSYSQQPY-NNQGQQQNMESSGSQGGRAPSY--------------- 102

Query: 922  HGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSS 981
                      +G + S  Q SGY QH       S+Y+Q        S S+   S      
Sbjct: 103  ------DQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQ-----HDSYSQNQQSYHSQRE 151

Query: 982  SYGQHGSGSRQSLG-HGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPY 1040
            +Y  H    R+ +  +G+   G G S    RGR   G       GP    SG    RG +
Sbjct: 152  NYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGR---GGYDKDGRGPMTGSSG--GDRGGF 206

Query: 1041 ESGSGHSSGLGHRESRSGQS----------SGYGQHGSSSGHSSTHGQHG-----STSGQ 1085
            ++  GH    G R     +S           G G+  S+        Q G       +G+
Sbjct: 207  KNFGGHRD-YGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGK 265

Query: 1086 SSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR-H 1144
                      +G+             S+          +  G+  + S + + P + R  
Sbjct: 266  PMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGG 325

Query: 1145 GSGSGRSSSSGQHGSGLGESSGFGHHESS-------SGQSSSYSQHGSGSGHSSGYGQHG 1197
            GSG GR    G  G G  +  G G  +S        S  + ++++  S +  +    +  
Sbjct: 326  GSGGGRRGRGGYRGRGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDS 384

Query: 1198 SRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSS 1257
              SG   RG  +G   G     G+   G R   G  R G G G   S G   SG      
Sbjct: 385  RPSGGDFRGRGYGGERGYRGRGGR--GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 442

Query: 1258 HGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS 1317
            +G   SG G    RG      G+       + G G+         G G+   +G +G   
Sbjct: 443  YGGDRSGGGYGGDRG-----GGYGG-----DRGGGYGG-----DRGGGYGGDRGGYGGDR 487

Query: 1318 GQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQ 1377
            G     D+ G    +    G RG       GYG   +  G    RG  GSG G   S G 
Sbjct: 488  GGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRG-GGSGYGGDRSGGY 546

Query: 1378 HGSGSGWSSSSGRHGSGSGQSSGFG 1402
             G  SG      R G   G   G+G
Sbjct: 547  GGDRSGGGYGGDRGGGYGGDRGGYG 571



 Score =  115 bits (287), Expect = 8e-25
 Identities = 161/609 (26%), Positives = 213/609 (34%), Gaps = 83/609 (13%)

Query: 124 ESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHN----SYSGQSSSY 179
           ++S S+S +    + SY +N  G    G        S+ + + G  N    SYS Q   Y
Sbjct: 30  QASQSYSGYGQTTDSSYGQNYSGYSSYGQ-------SYSQSYGGYENQKQSSYSQQP--Y 80

Query: 180 GEQNSDSHQSSGRGQCGSG-SGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKS-S 237
             Q    +  S   Q G   S   P+YGQ  S   QS  +   GS   QS+   QH S S
Sbjct: 81  NNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYS 140

Query: 238 SGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHG 297
             Q S +SQ  + S H+    +  SR G+ +RG            YG    G R   G+ 
Sbjct: 141 QNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRG------------YGGSQGGGRGRGGYD 188

Query: 298 RQGSGSRQSPSHVRHGSGSGHSSSHGQHG------SGSSYSYSRGHYESGSGQ---TSGF 348
           + G G     S    G G  +   H  +G      S S  S +   +  G G+   T   
Sbjct: 189 KDGRGPMTGSSGGDRG-GFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQV 247

Query: 349 GQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQ----HE 404
           G+     G      K G    +  +    G   G+A+ S     S++ +  +      H 
Sbjct: 248 GEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHG 307

Query: 405 SASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSG 464
           +  + S    +     G   G G+RG G G     G  G G    S      + S  +  
Sbjct: 308 NIIKVSFATRRPEFMRGGGSGGGRRGRG-GYRGRGGFQGRGGDPKSGDWVCPNPSCGNMN 366

Query: 465 FGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGS 524
           F    S ++ +    +    SG       +G   G   RG R G   G    YG    G 
Sbjct: 367 FARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGG----YG----GD 418

Query: 525 RQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGL 584
           R         SG G     S G   SG R    YG    G G    RG    G G   G 
Sbjct: 419 R---------SGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRG---GGYGGDRGG 466

Query: 585 GHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSS 644
           G+   R G   GYG  G   G+    G  G   G     G  G   G    +G    G  
Sbjct: 467 GYGGDRGG---GYG--GDRGGYG---GDRGGGYG-----GDRGGYGGDRGGYGGDRGG-- 511

Query: 645 QSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGS-GWSSSNGPHGSVSGQSSGFGH 703
               YG    G G   SRG +G D G  S YG   SG  G   S G +G   G   G G 
Sbjct: 512 ----YGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYG-GD 566

Query: 704 KSGSGQSSG 712
           + G G   G
Sbjct: 567 RGGYGGKMG 575



 Score =  114 bits (285), Expect = 1e-24
 Identities = 156/596 (26%), Positives = 211/596 (35%), Gaps = 62/596 (10%)

Query: 176 SSSYGEQNSDSHQSSGRGQCGS-GSGQSPNYGQHGSGSGQSSSNDTHGSGSGQS-SGFSQ 233
           S SYG+   +    S  G  GS G GQ+    Q  SG GQ++      S  GQ+ SG+S 
Sbjct: 4   SGSYGQSGGEQQSYSTYGNPGSQGYGQA---SQSYSGYGQTTD-----SSYGQNYSGYSS 55

Query: 234 HKSSSGQS-SGYSQHGSGSGHSSGYGQHGSRSGQSSRGERH-RSSSGSSSSYGQHGSGSR 291
           +  S  QS  GY      S     Y   G +    S G +  R+ S     YGQ  S  +
Sbjct: 56  YGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQ 115

Query: 292 QSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQH 351
           QS     QGS   QS    +H S S +  S+  H    +YS+   H +      S +G+ 
Sbjct: 116 QSGYDQHQGSYDEQSNYDQQHDSYSQNQQSY--HSQRENYSH---HTQDDRRDVSRYGED 170

Query: 352 ESGSGQSSG-------YSKHGSGSGHSSSQGQHGSTS--------GQASSSGQHGSSSRQ 396
             G G S G       Y K G G    SS G  G           G  + +     +S  
Sbjct: 171 NRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDN 230

Query: 397 SSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSS---G 453
           ++ + Q       +   G+     G    + + G       +    G   G ++ S    
Sbjct: 231 NTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDP 290

Query: 454 PYVSGS-GYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAG 512
           P    +  +  G   H +  + S    +     G  SG G+ G R G   RG  QG    
Sbjct: 291 PSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRG-RGGYRGRGGFQGRGGD 349

Query: 513 SSSSYGQHGSGSRQSLGHSRHGS-GSGQSPSPSRGRHESGSRQSSSYG-PHGYGS--GRS 568
             S      + S  ++  +R  S      P P   R   G  +   YG   GY    GR 
Sbjct: 350 PKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRG 409

Query: 569 SSRGPY---ESGSGH----SSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQ-HGSTSGQS 620
             RG Y    SG G+    SSG G+   RSG   GYG   S  G+    G  +G   G  
Sbjct: 410 GDRGGYGGDRSGGGYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGGDRGGGYGGDRGGG 467

Query: 621 SSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFG-------HSS 673
               + G   G    +G    G     R G  G   G    RG +G D G          
Sbjct: 468 YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGG 527

Query: 674 SYGQHGSGSGWSS--SNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYR 727
             G  G GSG+    S G  G  SG   G+G   G G       +G      + YR
Sbjct: 528 YGGDRGGGSGYGGDRSGGYGGDRSG--GGYGGDRGGGYGGDRGGYGGKMGGRNDYR 581



 Score =  113 bits (282), Expect = 3e-24
 Identities = 151/601 (25%), Positives = 210/601 (34%), Gaps = 106/601 (17%)

Query: 1635 SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGS 1694
            S  G +  S G+  SYS +G+    S GYGQ    + QS  G  +G ++ SS  YGQ+ S
Sbjct: 2    SDSGSYGQSGGEQQSYSTYGNPG--SQGYGQ----ASQSYSG--YGQTTDSS--YGQNYS 51

Query: 1695 GSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGP----------- 1743
            G         Q  G  ++  +  +     ++    Q+   SG    R P           
Sbjct: 52   GYSSYGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQD 111

Query: 1744 -YESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQ 1802
             Y+ +SG+    G ++  S +   +  +      + SQ ++ S   Q    D   S  G+
Sbjct: 112  SYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDV--SRYGE 169

Query: 1803 SSSHGQHGSGSSQSSSYGQQG-SGSGQSPSRGRHGSGSGHSSSYGQH---GSGSGWSSSS 1858
             +     G G SQ    G+ G    G+ P  G  G   G   ++G H   G  +   S S
Sbjct: 170  DN----RGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSES 225

Query: 1859 GRHGSGSGQSSGFGHHESSSWQSSGYTQHG-------SGSGHSSSY--EQHGSRSGQSSR 1909
                + +    G G   S+      + Q G       +G    + Y  +  G   G+++ 
Sbjct: 226  DNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATV 285

Query: 1910 G-----------------EQHGS-------------SSGSSSSYGQHGSGSRQSLG---- 1935
                              E HG+               G  S  G+ G G  +  G    
Sbjct: 286  SFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQG 345

Query: 1936 -HGQHGSGSGQSPSPSRGR----HGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGL 1990
              G   SG    P+PS G       +   Q +   P  S       RG    G G   G 
Sbjct: 346  RGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRG---RGYGGERGY 402

Query: 1991 GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSS 2050
              R  R G   GYG   S  G+       G  SG  S  G  G  SG        G G  
Sbjct: 403  RGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG-------GGYGGD 455

Query: 2051 QSSGY-GRQGSGSGQSPGHG----QRGSGSRQSPSYG--RHGSGSGRSSSSGQHGPGLGE 2103
            +  GY G +G G G   G G    + G G  +   YG  R G G  R    G  G   G+
Sbjct: 456  RGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGD 515

Query: 2104 SSGFGHHESSSGQSSSYSQHGSGSGH----SSGYGQHGSRSGQSSRGERHGSSSGSSSRY 2159
              G+G   S  G        G GSG+    S GYG  G RSG    G+R G   G    Y
Sbjct: 516  RGGYGGDRSRGGYG---GDRGGGSGYGGDRSGGYG--GDRSGGGYGGDRGGGYGGDRGGY 570

Query: 2160 G 2160
            G
Sbjct: 571  G 571



 Score =  111 bits (278), Expect = 9e-24
 Identities = 175/664 (26%), Positives = 223/664 (33%), Gaps = 95/664 (14%)

Query: 1569 SSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHG 1628
            S S+GQ G      S YG  GS           G G     SYG++ SG    SS GQ  
Sbjct: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGY---SSYGQ-- 58

Query: 1629 SGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSS-SRSSS 1687
                 S  +G +E+   + SSYSQ          Y   G +    S G + G + S    
Sbjct: 59   ---SYSQSYGGYENQ--KQSSYSQQP--------YNNQGQQQNMESSGSQGGRAPSYDQP 105

Query: 1688 RYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGS-GLGHSSSHGQHGSGSGRSSSRGPYES 1746
             YGQ  S  +QS     QGS   QS    +H S      S H Q  + S  +       S
Sbjct: 106  DYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVS 165

Query: 1747 RSGHSSV-FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 1805
            R G  +  +G  + G      Y + G G     S G  G         D  G  T   S 
Sbjct: 166  RYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDY-GPRTDADSE 224

Query: 1806 HGQHGSGSSQSSSYGQQGSGSGQSPSR-GRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 1864
                 S +S +++   QG G G S  + G      G   +  + G       +    G  
Sbjct: 225  -----SDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKP 279

Query: 1865 SGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYG 1924
             G+++       S+  +  +       G+        +R  +  RG   GS  G     G
Sbjct: 280  KGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVS-FATRRPEFMRGG--GSGGGRRGRGG 336

Query: 1925 QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG----SGSGQSSSYGPYGSGSGWSSSRGPY 1980
              G G  Q  G G   SG    P+PS G       +   Q +   P  S       RG  
Sbjct: 337  YRGRGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRG-- 393

Query: 1981 ESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSS 2040
              G G   G   R  R G   GYG   S  G+       G  SG  S  G  G  SG   
Sbjct: 394  -RGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGG-- 450

Query: 2041 SHGQHGSGSSQSSGYGR-QGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGP 2099
                 G G  +  GYG  +G G G     G RG G      YG    G G     G  G 
Sbjct: 451  -----GYGGDRGGGYGGDRGGGYG-----GDRGGG------YGGDRGGYG-----GDRGG 489

Query: 2100 GLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSS--- 2156
            G G                     G   G   GYG  G R G    G+R G     S   
Sbjct: 490  GYG------------------GDRGGYGGDRGGYG--GDRGGYG--GDRGGYGGDRSRGG 527

Query: 2157 ---SRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGP 2213
                R G  G G  +S G+G   SG G+   RG  G   G    +G  G   GR+  R  
Sbjct: 528  YGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRG--GGYGGDRGGYG--GKMGGRNDYRND 583

Query: 2214 YESR 2217
              +R
Sbjct: 584  QRNR 587



 Score =  111 bits (278), Expect = 9e-24
 Identities = 155/612 (25%), Positives = 211/612 (34%), Gaps = 80/612 (13%)

Query: 2249 SQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS---GQSPSRGRH 2305
            S GQ G      ST+   GS     +S    G G +  SSYGQ  SG    GQS S+   
Sbjct: 6    SYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYG 65

Query: 2306 GSGSGHSSSYGQHG-SGSGWSSSSGRHGSGSGQSSGFGH----HESSSWQSSGYTQHGSG 2360
            G  +   SSY Q   +  G   +    GS  G++  +       + S  Q SGY QH   
Sbjct: 66   GYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGS 125

Query: 2361 SGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLG-HGQHGSGSGQSPSP 2419
                S+Y+Q      Q+ +     S      +Y  H    R+ +  +G+   G G S   
Sbjct: 126  YDEQSNYDQQHDSYSQNQQ-----SYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGG 180

Query: 2420 SRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSS-------- 2471
             RGR   G        P    SG    RG +++  GH    G R     +S         
Sbjct: 181  GRGR---GGYDKDGRGPMTGSSG--GDRGGFKNFGGHRD-YGPRTDADSESDNSDNNTIF 234

Query: 2472 --GYGQHGSSSGHSSTHGQHG-----STSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG 2524
              G G+  S+        Q G       +G+          +G+             S+ 
Sbjct: 235  VQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAK 294

Query: 2525 YGRQGSGSGQSPGHGQRGSGSRQSPSYGRHG-SGSGRSSSSGQHGSGLGESSGFGHHESS 2583
                     +  G+  + S + + P + R G SG GR    G  G G  +  G G  +S 
Sbjct: 295  AAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRG-GDPKSG 353

Query: 2584 -------SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGS 2636
                   S  + ++++  S +  +    +    SG   RG  +G   G     G+   G 
Sbjct: 354  DWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGR--GGD 411

Query: 2637 RQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQ 2696
            R   G  R G G G   S G   SG      +G   SG G    RG      G+      
Sbjct: 412  RGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGG-----GYGG---- 462

Query: 2697 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYG-HRGSGSSQ 2755
             + G G+       G G G     G  G   G     D+ G   G    YG  RG     
Sbjct: 463  -DRGGGYGG---DRGGGYG-----GDRGGYGG-----DRGGGYGGDRGGYGGDRGGYGGD 508

Query: 2756 SSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKG 2815
              GYG    G G   S G +G   G  S YG   SG     GY    SG    GY   +G
Sbjct: 509  RGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSG-----GYGGDRSGG---GYGGDRG 560

Query: 2816 GSNHDGGSSGSY 2827
            G    GG  G Y
Sbjct: 561  GGY--GGDRGGY 570



 Score =  108 bits (270), Expect = 8e-23
 Identities = 145/588 (24%), Positives = 192/588 (32%), Gaps = 54/588 (9%)

Query: 2151 SSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSG-----S 2205
            S SGS   YGQ G   +  S +G  GS      S+   G G    SS+GQ+ SG      
Sbjct: 2    SDSGS---YGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQ 58

Query: 2206 GRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 2265
              S S G YE++   SS   Q  +  G        GS  G   S  Q     GQ  ++DQ
Sbjct: 59   SYSQSYGGYENQK-QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQ--PDYGQQDSYDQ 115

Query: 2266 EGSSTGQSSSHGQHGSGSSQSSSYGQ-QGSGSGQSPSRGRHGSGSGHS-SSYGQHGSGSG 2323
            +        S+ +  +   Q  SY Q Q S   Q  +   H        S YG+   G G
Sbjct: 116  QSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYG 175

Query: 2324 WSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERH 2383
             S   GR G G     G G    SS    G  ++  G           S S  S      
Sbjct: 176  GSQGGGR-GRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIF 234

Query: 2384 GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQS-----PSPSRGRHGSGSGQSSSYSPYG 2438
                G   S  Q G   +Q +G  +    +G+           G+    +  S    P  
Sbjct: 235  VQGLGEGVSTDQVGEFFKQ-IGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSA 293

Query: 2439 SGS----------------GWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG- 2481
              +                 +++ R  +  G G   G   R    G+    G+ G     
Sbjct: 294  KAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSG 353

Query: 2482 -----HSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 2536
                 + S    + +     + C +      + S     G G     GY  +G   G   
Sbjct: 354  DWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRG 413

Query: 2537 GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG 2596
            G+G    G R    YG   S  G  S     G   G+ SG G+     G        G G
Sbjct: 414  GYG----GDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYG 469

Query: 2597 SGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHY-GQHGSGSRQSSGHGRQGSGSGQSPSR 2655
                 GYG  G R G    G+R G   G    Y G  G       G+G    G G   SR
Sbjct: 470  GDRGGGYG--GDRGGYG--GDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSR 525

Query: 2656 GRHGSGLGHSSSHGQHGSGS-GRSSSRGPYESRLGHSSVFGQHESGSG 2702
            G +G   G  S +G   SG  G   S G Y    G    +G    G G
Sbjct: 526  GGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGG--YGGDRGGYG 571



 Score =  107 bits (266), Expect = 2e-22
 Identities = 142/583 (24%), Positives = 189/583 (32%), Gaps = 51/583 (8%)

Query: 1686 SSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSG-----SGRSSS 1740
            S  YGQ G   +  S +G  GS      S+   G G    SS+GQ+ SG        S S
Sbjct: 4    SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQS 63

Query: 1741 RGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST 1800
             G YE++   SS   Q  +  G        GS  G   S  Q     GQ  ++DQ+    
Sbjct: 64   YGGYENQK-QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQ--PDYGQQDSYDQQSGYD 120

Query: 1801 GQSSSHGQHGSGSSQSSSYGQ-QGSGSGQSPSRGRHGSGSGHS-SSYGQHGSGSGWSSSS 1858
                S+ +  +   Q  SY Q Q S   Q  +   H        S YG+   G G S   
Sbjct: 121  QHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGG 180

Query: 1859 GRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSG 1918
            GR G G     G G    SS    G  ++  G           S S  S          G
Sbjct: 181  GR-GRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLG 239

Query: 1919 SSSSYGQHGSGSRQSLGHGQHGSGSGQS-----PSPSRGRHGSGSGQSSSYGPYGSGS-- 1971
               S  Q G   +Q +G  +    +G+           G+    +  S    P    +  
Sbjct: 240  EGVSTDQVGEFFKQ-IGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAID 298

Query: 1972 --------------GWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG------ 2011
                           +++ R  +  G G   G   R    G+    G+ G          
Sbjct: 299  WFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCP 358

Query: 2012 HSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQR 2071
            + S    + +     + C +      + S     G G     GY  +G   G   G+G  
Sbjct: 359  NPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYG-- 416

Query: 2072 GSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSS 2131
              G R    YG   S  G  S     G   G+ SG G+     G        G G     
Sbjct: 417  --GDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGG 474

Query: 2132 GYGQHGSRSGQSSRGERHGSSSGSSSRY-GQHGSGSRQSSGHGRQGSGSGHSPSRGRHGS 2190
            GYG  G R G    G+R G   G    Y G  G       G+G    G G   SRG +G 
Sbjct: 475  GYG--GDRGGYG--GDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGG 530

Query: 2191 GSGHSSSHGQHGSGS-GRSSSRGPYESRSGHSSVFGQHESGSG 2232
              G  S +G   SG  G   S G Y    G    +G    G G
Sbjct: 531  DRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGG--YGGDRGGYG 571



 Score =  103 bits (257), Expect = 2e-21
 Identities = 154/634 (24%), Positives = 228/634 (35%), Gaps = 81/634 (12%)

Query: 319 SSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHG 378
           S S+GQ G G   SYS      G+  + G+GQ       S  YS +G  +  S  Q   G
Sbjct: 4   SGSYGQSG-GEQQSYST----YGNPGSQGYGQ------ASQSYSGYGQTTDSSYGQNYSG 52

Query: 379 -STSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGS--GQSPGHGQRGSGSGQ 435
            S+ GQ+ S    G  +++ SSY Q +  +     +   SSGS  G++P + Q     GQ
Sbjct: 53  YSSYGQSYSQSYGGYENQKQSSYSQ-QPYNNQGQQQNMESSGSQGGRAPSYDQ--PDYGQ 109

Query: 436 SPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGY-TQHGSGSGHSSGHGQH 494
             S  Q     G     G Y   S Y      H+S S++   Y +Q  + S H+    + 
Sbjct: 110 QDSYDQQS---GYDQHQGSYDEQSNYDQ---QHDSYSQNQQSYHSQRENYSHHTQDDRRD 163

Query: 495 GSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQ 554
            SR G+ +RG            YG    G R   G+ + G G     + S G    G + 
Sbjct: 164 VSRYGEDNRG------------YGGSQGGGRGRGGYDKDGRG---PMTGSSGGDRGGFKN 208

Query: 555 SSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHG 614
              +  +G  +   S     ++ +    GLG   S    +   G+     G   T+ + G
Sbjct: 209 FGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVS----TDQVGEFFKQIGIIKTNKKTG 264

Query: 615 STSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRY--GQQGSGSGQSPSRGRHGSDFGHS 672
                  +    G   G+++        +  +  +  G++  G+    S      +F   
Sbjct: 265 KPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRG 324

Query: 673 SSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSG-------SGQSSGYSQHGSGSSHSSG 725
                 GSG G     G  G    Q  G   KSG       S  +  +++  S +  +  
Sbjct: 325 G-----GSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEP 379

Query: 726 YRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSS 785
             +    SG   R   +G   G    Y   G       G+G   SG G+   R     SS
Sbjct: 380 RPEDSRPSGGDFRGRGYGGERG----YRGRGGRGGDRGGYGGDRSGGGYGGDR-----SS 430

Query: 786 GHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHG 845
           G   S  + G G     S G Y  G  +  G+G  + G G G  + G   G+   +G +G
Sbjct: 431 GGGYSGDRSGGGYGGDRSGGGY--GGDRGGGYG-GDRGGGYGGDRGG---GYGGDRGGYG 484

Query: 846 STSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSG---- 901
              G     G      G    YG       +   RG +G    +    G RG GSG    
Sbjct: 485 GDRG-GGYGGDRGGYGGDRGGYGGDRGG--YGGDRGGYGGDRSRGGYGGDRGGGSGYGGD 541

Query: 902 QSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHK 935
           +S  YG   SG G     G  G   G   G+G K
Sbjct: 542 RSGGYGGDRSGGGYGGDRG--GGYGGDRGGYGGK 573



 Score =  102 bits (255), Expect = 4e-21
 Identities = 144/592 (24%), Positives = 202/592 (34%), Gaps = 68/592 (11%)

Query: 508  GSSAGSSSSYGQHGSGSRQSLGH-SRHGSGSGQSPSPSRGRHESG-----SRQSSSYGPH 561
            G S G   SY  +G+   Q  G  S+  SG GQ+   S G++ SG        S SYG +
Sbjct: 8    GQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYGGY 67

Query: 562  GYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQ--HGSSSGHSSTHG--QH-GST 616
                  S S+ PY +  G    +    S+ G++  Y Q  +G    +    G  QH GS 
Sbjct: 68   ENQKQSSYSQQPYNN-QGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSY 126

Query: 617  SGQSSSCGQHGATS-GQSSSHGQHGSGSSQS-------SRYGQ--QGSGSGQSPSRGRHG 666
              QS+   QH + S  Q S H Q  + S  +       SRYG+  +G G  Q   RGR G
Sbjct: 127  DEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGG 186

Query: 667  SDF-GHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQH-GSGSSHSS 724
             D  G     G  G   G   + G H     ++        S  ++ + Q  G G S   
Sbjct: 187  YDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQ 246

Query: 725  --------GYRKHGSRSGQSS----RSEQHGSSSGLSS-SYGQHGSGS--------HQSS 763
                    G  K   ++G+        +  G   G ++ S+    S           +  
Sbjct: 247  VGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFH 306

Query: 764  GHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESG 823
            G+  + S +   P  +R G S G     G +          G  +SG         + S 
Sbjct: 307  GNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCP----NPSC 362

Query: 824  SGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRH 883
                +++  S +     +      SG       +    G     G+      +   R   
Sbjct: 363  GNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGG 422

Query: 884  GSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSG 943
            G G  +S G G  G  SG      R G G G     G  G G G   G G+    G   G
Sbjct: 423  GYGGDRSSGGGYSGDRSGGGYGGDRSGGGYG-----GDRGGGYGGDRGGGYGGDRGGGYG 477

Query: 944  YTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1003
              + G G      Y   G R G        G   G    YG    G       G +G   
Sbjct: 478  GDRGGYGGDRGGGY--GGDRGGYGG---DRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDR 532

Query: 1004 GQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESG--SGHSSGLGHR 1053
            G       G  G G  +S  YG  RSG G+   RG    G   G+   +G R
Sbjct: 533  G-------GGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGR 577



 Score = 84.3 bits (207), Expect = 2e-15
 Identities = 131/544 (24%), Positives = 185/544 (34%), Gaps = 64/544 (11%)

Query: 90  GKDYCQVSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAG------ENDSYSRN 143
           G+ Y Q  G       +++Q++   +++  N + +     SS S G      +   Y + 
Sbjct: 57  GQSYSQSYGG------YENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQ 110

Query: 144 VRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSD-SHQSSGRGQCGSGSGQS 202
                + G +        Q ++  QH+SYS    SY  Q  + SH +    +  S  G+ 
Sbjct: 111 DSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGED 170

Query: 203 PNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGS 262
            N G  GS  G          G G  +G     SS G   G+   G   GH   YG    
Sbjct: 171 -NRGYGGSQGGGRGRGGYDKDGRGPMTG-----SSGGDRGGFKNFG---GHRD-YGPRTD 220

Query: 263 RSGQSSRGERHR---SSSGSSSSYGQHGSGSRQ-SLGHGRQGSG----SRQSPSHVRHGS 314
              +S   + +       G   S  Q G   +Q  +    + +G    +  +        
Sbjct: 221 ADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPK 280

Query: 315 GSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFG----QHESGSGQSSGYSKHGSGSGH 370
           G    S      + ++  +  G    G+     F     +   G G   G    G   G 
Sbjct: 281 GEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGR 340

Query: 371 SSSQGQHGS-TSGQ---ASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGH 426
              QG+ G   SG     + S  + + +R++S    +E     S   G    G G     
Sbjct: 341 GGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGER 400

Query: 427 GQRGSGSGQSPSSG----QHGTGFGRSSSSGPYVSGSGYSSGFGHHES----SSEHSSGY 478
           G RG G       G    + G G+G   SSG   SG     G+G   S      +   GY
Sbjct: 401 GYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGY 460

Query: 479 -TQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSG- 536
               G G G   G G  G R G    G+R G   G    YG    G R   G  R G G 
Sbjct: 461 GGDRGGGYGGDRGGGYGGDRGGYG--GDRGGGYGGDRGGYG----GDRGGYGGDRGGYGG 514

Query: 537 --SGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQS 594
              G     SRG +  G R   S    GYG  RS   G   SG G+    G      G  
Sbjct: 515 DRGGYGGDRSRGGY-GGDRGGGS----GYGGDRSGGYGGDRSGGGYGGDRG--GGYGGDR 567

Query: 595 SGYG 598
            GYG
Sbjct: 568 GGYG 571



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 118/507 (23%), Positives = 154/507 (30%), Gaps = 66/507 (13%)

Query: 93  YCQVSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDS-YSRNVRGSLKPG 151
           Y Q  GS      +  Q +     ++    Q  ++SH +     + S Y  + RG    G
Sbjct: 119 YDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGY--GG 176

Query: 152 TESISR-RLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSG-RGQCGSGSGQSPNYGQHG 209
           ++   R R  + +D  G     SG     G +N   H+  G R    S S  S N     
Sbjct: 177 SQGGGRGRGGYDKDGRGPMTGSSGGDRG-GFKNFGGHRDYGPRTDADSESDNSDNNTIFV 235

Query: 210 SGSGQSSSNDTHGSGSGQSSGFSQHKSS------------SGQSSGYSQHGSGSGHSS-- 255
            G G+  S D  G    Q      +K +            +G+  G +        S+  
Sbjct: 236 QGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKA 295

Query: 256 ------GYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSH 309
                 G   HG+    S    R     G  S  G+ G G  +  G G QG G       
Sbjct: 296 AIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRG-GFQGRGGDPKSGD 354

Query: 310 VRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSG 369
               + S  + +  +  S +  +  R      SG          G  +  GY       G
Sbjct: 355 WVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSG----------GDFRGRGYGGERGYRG 404

Query: 370 HSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQR 429
                G  G   G  S  G  G  S      G   S  R   G G   SG G     G R
Sbjct: 405 RGGRGGDRGGYGGDRSGGGYGGDRSS-----GGGYSGDRSGGGYGGDRSGGGYG---GDR 456

Query: 430 GSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSS 489
           G G G     G  G G+G     G      GY    G          G  + G G     
Sbjct: 457 GGGYG-----GDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGG 511

Query: 490 GHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHE 549
             G  G   G  SRG   G   G  S YG   SG     G  R G G G           
Sbjct: 512 YGGDRGGYGGDRSRG-GYGGDRGGGSGYGGDRSG---GYGGDRSGGGYG----------- 556

Query: 550 SGSRQSSSYGPHGYGSGRSSSRGPYES 576
            G R     G  G   G+   R  Y +
Sbjct: 557 -GDRGGGYGGDRGGYGGKMGGRNDYRN 582



 Score = 61.6 bits (148), Expect = 1e-08
 Identities = 73/269 (27%), Positives = 97/269 (36%), Gaps = 37/269 (13%)

Query: 2509 SSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHG 2568
            S S+GQ G      S YG  G     S G+GQ    S+    YG+    S   + SG   
Sbjct: 4    SGSYGQSGGEQQSYSTYGNPG-----SQGYGQ---ASQSYSGYGQTTDSSYGQNYSGYSS 55

Query: 2569 SGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG-SSSGSSS 2627
             G   S  +G +E+   + SSYSQ          Y   G +    S G + G + S    
Sbjct: 56   YGQSYSQSYGGYENQ--KQSSYSQ--------QPYNNQGQQQNMESSGSQGGRAPSYDQP 105

Query: 2628 HYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGS-GLGHSSSHGQHGSGSGRSSSRGPYES 2686
             YGQ  S  +QS     QGS   QS    +H S      S H Q  + S  +       S
Sbjct: 106  DYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVS 165

Query: 2687 RLGHSS-VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 2745
            R G  +  +G  + G      Y + G G          GS+ G    F     + G    
Sbjct: 166  RYGEDNRGYGGSQGGGRGRGGYDKDGRGP-------MTGSSGGDRGGF----KNFGGHRD 214

Query: 2746 YGHRGSGSSQSSGYGRH-----GAGSGQS 2769
            YG R    S+S     +     G G G S
Sbjct: 215  YGPRTDADSESDNSDNNTIFVQGLGEGVS 243



 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 70/253 (27%), Positives = 100/253 (39%), Gaps = 48/253 (18%)

Query: 2575 SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGS 2634
            S  G +  S G+  SYS +G+    S GYGQ    + QS  G  +G ++ SS  YGQ+ S
Sbjct: 2    SDSGSYGQSGGEQQSYSTYGNPG--SQGYGQ----ASQSYSG--YGQTTDSS--YGQNYS 51

Query: 2635 GSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVF 2694
            G           S  GQS           +S S+G + +    S S+ PY ++ G     
Sbjct: 52   GY----------SSYGQS-----------YSQSYGGYENQKQSSYSQQPYNNQ-GQQQNM 89

Query: 2695 GQHESGSGHSSAYSQHGSGSGHFCSQ----GQHGSTSGQSSTFDQEGSSTGQSSSYGHRG 2750
                S  G + +Y Q   G      Q     QH  +  + S +DQ+  S  Q+    H  
Sbjct: 90   ESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYH-- 147

Query: 2751 SGSSQSSGYGRHGAGSGQSLS-HGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDG 2809
               SQ   Y  H     + +S +G    G G     G  G G G+  GY + G G     
Sbjct: 148  ---SQRENYSHHTQDDRRDVSRYGEDNRGYG-----GSQGGGRGR-GGYDKDGRGPMTGS 198

Query: 2810 YSYCKGGSNHDGG 2822
                +GG  + GG
Sbjct: 199  SGGDRGGFKNFGG 211



 Score = 39.7 bits (91), Expect = 0.043
 Identities = 42/114 (36%), Positives = 52/114 (45%), Gaps = 18/114 (15%)

Query: 2737 GSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSG-SGQS 2795
            G S G+  SY   G+  SQ  GYG+    + QS S    G G    SSYGQ+ SG S   
Sbjct: 8    GQSGGEQQSYSTYGNPGSQ--GYGQ----ASQSYS----GYGQTTDSSYGQNYSGYSSYG 57

Query: 2796 SGYSQ-HGSGSGQDGYSYCKGGSNHDG-----GSSGSYFLSFPSSTSPYEYVQE 2843
              YSQ +G    Q   SY +   N+ G      SSGS     PS   P +Y Q+
Sbjct: 58   QSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQP-DYGQQ 110



 Score = 37.4 bits (85), Expect = 0.21
 Identities = 25/92 (27%), Positives = 35/92 (38%), Gaps = 6/92 (6%)

Query: 2754 SQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYC 2813
            S S  YG+ G       ++G  GS     +S    G G    S Y Q+ SG    G SY 
Sbjct: 2    SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYS 61

Query: 2814 KGGSNHDGGSSGSYFLSFPSSTSPYEYVQEQR 2845
            +    ++     SY      S  PY    +Q+
Sbjct: 62   QSYGGYENQKQSSY------SQQPYNNQGQQQ 87



 Score = 37.0 bits (84), Expect = 0.28
 Identities = 43/154 (27%), Positives = 55/154 (35%), Gaps = 32/154 (20%)

Query: 2719 SQGQHGSTSGQSSTFDQEGS-----STGQSSSYGHRGSGSSQSSGYGRHGAG---SGQSL 2770
            S GQ G      ST+   GS     ++   S Y     G +  S YG++ +G    GQS 
Sbjct: 6    SYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGY-----GQTTDSSYGQNYSGYSSYGQSY 60

Query: 2771 SHGRHGSGSGQSSSYGQH--------------GSGSGQSSGYSQHGSGSGQDGYSYCKGG 2816
            S    G  + + SSY Q               GS  G++  Y Q   G  QD Y    G 
Sbjct: 61   SQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQ-QDSYDQQSGY 119

Query: 2817 SNHDGGSSGSYFLSFPSSTSPYEYVQEQRCYFYQ 2850
              H     GSY            Y Q Q+ Y  Q
Sbjct: 120  DQH----QGSYDEQSNYDQQHDSYSQNQQSYHSQ 149


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score =  127 bits (319), Expect = 2e-28
 Identities = 422/1839 (22%), Positives = 596/1839 (32%), Gaps = 266/1839 (14%)

Query: 269  RGERHRSSSGSSSSYGQHGSGSRQSLGH-GRQGSGSRQSPSHVRHGSGSGHSSSHGQ--- 324
            + ER R++ G S SY    S   Q      +Q +     P  +   S S  S +  Q   
Sbjct: 131  KNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKK 190

Query: 325  -----HGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGS 379
                  G  S  S  R   +  S +     + ES   +    +           + +  S
Sbjct: 191  KKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRS 250

Query: 380  TSGQASSSGQHGSSSRQS-SSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPS 438
            T+    S   H S+S  S SS     S SR ++ +   ++ +G+SP       G G +P 
Sbjct: 251  TTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPF 310

Query: 439  SGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSG-------- 490
            S    T   R SS  P  +    SS +   +   +  S      S    S+G        
Sbjct: 311  SEPGTTSTQRPSS--PETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTP 368

Query: 491  -----HG-----------------QHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSL 528
                 HG                      S    R   +       SS  +    S Q  
Sbjct: 369  LLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPT 428

Query: 529  GHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQE 588
              SRH S S +SP P+      GS +  S  P      RS  R   +    H+       
Sbjct: 429  KVSRHASSSPESPKPAPA---PGSHREISSSP--TSKNRSHGRAKRDKSHSHTPSRRMGR 483

Query: 589  SRSGQSSGYGQHGSSS----GHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSS 644
            SRS  ++  G+  S +    GHS +       S  +   G+  +   +  S      G S
Sbjct: 484  SRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWS 543

Query: 645  QSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHK 704
            +S    ++G        R    S      S  +  +  G S S  P    S   +    +
Sbjct: 544  RSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRR 603

Query: 705  SGSGQSSGYSQHGSGSSHSSGYRKHGSRS--GQSSRSEQHGSSSGLSSSYGQHGSGSHQS 762
            S   +S   ++ G   S +   R+  +RS   + SRS      SG S S      G  +S
Sbjct: 604  S---RSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRS 660

Query: 763  SGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHES 822
                R+G     +P+R      SG S S      G S S +     S S      G+  S
Sbjct: 661  RTPARRGRSRSRTPAR-----RSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHS 715

Query: 823  GSGQGYSQHGSASGH----FSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHAS 878
             + Q   + GS+S       +SQ R  S S       +  S   +S S  + ++ S  + 
Sbjct: 716  RTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSL 775

Query: 879  GRGRHGSG-----SGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFG 933
             R   GS        Q+P    R SGS Q  +  R      RSSSS      S   S   
Sbjct: 776  RRSLSGSSPCPKQKSQTPPRRSR-SGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQS 834

Query: 934  HKSSSGQ---SSGYTQHGSGSGHSSSYEQHGSRSGQS-----------SRSEQHGSSSGS 979
            H SSS      SG            + EQ  +   +S           SR+    S SGS
Sbjct: 835  HSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGS 894

Query: 980  SSSYGQHGSGSRQS--------------LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYG 1025
            S    +  +  RQS              +   Q       SPSPSR    +   +S S  
Sbjct: 895  SPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVS 954

Query: 1026 PYRSGSGWSSSRGPYESGSGHSS-------GLGHRESRSGQSSGYGQHGSSSGHSSTHGQ 1078
            P    S   S   P  S SG SS           R+S SG  S Y +  + +        
Sbjct: 955  PC---SNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGP---- 1007

Query: 1079 HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQS 1138
              S SG  S C Q    S  S      GS S  +      G  S   PG    G  S Q 
Sbjct: 1008 --SLSGSKSPCPQE--KSKDSLVQSCPGSLSLCA------GVKSSTPPGESYFGVSSLQL 1057

Query: 1139 PSYGRHGSGSGRSSSSGQHGSGLGESS-GFGHHESSSGQSSSY-SQHGSGSGHSSGYGQH 1196
                      G+S +S  H S          H ES S QS S  S  G  S  SS   + 
Sbjct: 1058 ---------KGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTEL 1108

Query: 1197 GSRSG-QSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHS 1255
             SRS  +  RGE   S    S    +       SS +    S S    SR          
Sbjct: 1109 ASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKM 1168

Query: 1256 SSHGQHGSGSGRSSSRG-----PYESRSGHSSVF-------GQHESGSGHSSAYSQHGSG 1303
            +   Q  + +     +      P + R   S VF        +  SG+G S    +  S 
Sbjct: 1169 ALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSA 1228

Query: 1304 ------------------------SGHFCSQGQHGSTSGQSSTFDQEGS-------STGQ 1332
                                      H  S+ +  STS   S+ + E            Q
Sbjct: 1229 LPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQ 1288

Query: 1333 SSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYG-----QHGSGSGWSSS 1387
            S +        S +S +G    G   SP      +     +S+G     ++    G   +
Sbjct: 1289 SQASLEAVEVPSMASSWG----GPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMN 1344

Query: 1388 SGRHGSGSGQSSGFGHHESSSWQSSGCTQHGS-GSGHSSS------YEQHGSRSGQSSRG 1440
            +G         +G   ++  +  S    +  +  SGHSSS       E+ G  S QS   
Sbjct: 1345 TGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISS 1404

Query: 1441 ----------ERHGSSSGSS-----------SSYGQHGS--GSRQSLGHGQHGSGSGQSP 1477
                       R  SSS SS           S   + GS  G R   G     S SG SP
Sbjct: 1405 PVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSP 1464

Query: 1478 -------SPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQS 1530
                   +PSRGR    S       P    +    SR P  S   ++  L  +  RSG  
Sbjct: 1465 GMKDIPRTPSRGRSECDSSPEPKALPQ---TPRPRSRSP-SSPELNNKCLTPQRERSGSE 1520

Query: 1531 SGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG-RQG 1589
            S   Q    +   +  GQ  S SG S       ++S Q  S       S   +    RQ 
Sbjct: 1521 SSVDQ---KTVARTPLGQR-SRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQR 1576

Query: 1590 SGSGQSPGHGQRGSGSRQSPSYGRHGSG-----SGRSSSSGQHGSGLGES------SGFG 1638
            S SG SP   +  S SR SP   R GS        R++   Q GS               
Sbjct: 1577 SRSGSSP---EVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALP 1633

Query: 1639 HHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQ 1698
                S   S        GS  +    +H  +S  + RG R     ++ SR       SR 
Sbjct: 1634 RRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRS 1693

Query: 1699 SSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHE 1758
            S    R+   S +  SR    S    S +  +H      SS     +SRS          
Sbjct: 1694 SPELTRKARLSRR--SRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRR------ 1745

Query: 1759 SGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSS 1818
                 SS  ++  S  G   S    G    +S +  ++  +T +     +  SGSSQS+S
Sbjct: 1746 --RSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRR-----RDRSGSSQSTS 1798

Query: 1819 YGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSS 1878
              +Q S S    +R R G    HS S  +  S    S +S R   G  ++       S S
Sbjct: 1799 RRRQRSRSRSRVTRRRRGGSGYHSRSPARQES----SRTSSRRRRGRSRTPPTSRKRSRS 1854

Query: 1879 WQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSS 1917
              S    +        +++ +  SR+   SR      +S
Sbjct: 1855 RTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTS 1893



 Score =  124 bits (310), Expect = 2e-27
 Identities = 421/1833 (22%), Positives = 582/1833 (31%), Gaps = 251/1833 (13%)

Query: 704  KSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSS 763
            K   G+ S  S        SS  +KH  RS   S+  +H S +  S           +  
Sbjct: 193  KKDRGRRSESSSPRRERKKSSKKKKH--RSESESKKRKHRSPTPKSKR-------KSKDK 243

Query: 764  GHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCG-HYESGSGQASGFGQHES 822
               R  S +    SR  H S+S  S+S        S S++   H  + +G++        
Sbjct: 244  KRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRR 303

Query: 823  GSGQG-YSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRG 881
            G G   +S+ G+ S    S      T+ +  SS   D    +        S S   S  G
Sbjct: 304  GEGDAPFSEPGTTSTQRPSSPE---TATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTG 360

Query: 882  RHGSGSGQSPGHGQRGSGSGQ---SPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSS 938
                    +P   +R  GS Q   +    +        +S  R  S           SSS
Sbjct: 361  PEPPAP--TPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSS 418

Query: 939  GQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQ 998
              S    Q    S H+SS          S  S +   + GS        +   +S G  +
Sbjct: 419  ESSPPSPQPTKVSRHASS----------SPESPKPAPAPGSHREISSSPTSKNRSHGRAK 468

Query: 999  HGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSG 1058
                   +PS   GR         S  P  +  G S SR P + G   S     R SRS 
Sbjct: 469  RDKSHSHTPSRRMGR---------SRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSA 519

Query: 1059 QSSGYGQHGSSSGHSSTHGQHG-STSGQSSSCGQ-HGASSGQSSSHGQHGSGSSQSSGYG 1116
            Q  G  +     G S +  + G S S  +   G+   A  G+S S      G S+S    
Sbjct: 520  QRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPA 579

Query: 1117 RQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQ 1176
            R+G    ++P   +R S SR +P+  R      RS +  + G     +       + S  
Sbjct: 580  RRGRSRSRTPA--RRRSRSR-TPTRRR-----SRSRTPARRGRSRSRTPARRRSRTRSPV 631

Query: 1177 SSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQG 1236
                              +  +R G+S R         S S      SG  +S    R+G
Sbjct: 632  RRRSRSRSPARRSGRSRSRTPARRGRS-RSRTPARRGRSRSRTPARRSGRSRSRTPARRG 690

Query: 1237 SGSGHSPSRGRHGS------GLGHSSS---HGQHGSGSGRS--SSRGPYESRSGHSSVFG 1285
                 +P RGR  S      G  HS +    G+ GS S R   S      SRS  S    
Sbjct: 691  RSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMK 750

Query: 1286 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQ 1345
            +    S  S + S   S +    S  +  S SG S    Q+  +  + S      SGSSQ
Sbjct: 751  KSRISSRRSRSLSSPRSKAKSRLSLRR--SLSGSSPCPKQKSQTPPRRSR-----SGSSQ 803

Query: 1346 SSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHE 1405
                 R       +P R    S S       +  S    SSSS      SG     G   
Sbjct: 804  PKAKSR-------TPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSIT 856

Query: 1406 SSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQS-- 1463
            S        T         S +E       +S    RH S SGSS    +  +  RQS  
Sbjct: 857  SPQANEQSVTPQ-----RRSCFESSPDPELKSRTPSRH-SCSGSSPPRVKSSTPPRQSPS 910

Query: 1464 ------------LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYE 1511
                        +   Q       SPSPSR    +   +S S SP  +       R  + 
Sbjct: 911  RSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHS 970

Query: 1512 SGSSHSSGLGH----RESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSG 1567
              SS  + +      R+S SG  S Y +  + +          S SG  S C Q    S 
Sbjct: 971  GSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGP------SLSGSKSPCPQE--KSK 1022

Query: 1568 QSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH 1627
             S      GS S  +      G  S   PG    G  S Q           G+S +S  H
Sbjct: 1023 DSLVQSCPGSLSLCA------GVKSSTPPGESYFGVSSLQL---------KGQSQTSPDH 1067

Query: 1628 GSGLGESS-GFGHHESSSGQSSSY-SQHGSGSGHSSGYGQHGSRSG-QSSRGERHGSSSR 1684
             S          H ES S QS S  S  G  S  SS   +  SRS  +  RGE   S   
Sbjct: 1068 RSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPML 1127

Query: 1685 SSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRG-- 1742
             S    +       SS +    S S    SR          +   Q  + +     +   
Sbjct: 1128 KSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKF 1187

Query: 1743 ---PYESRSGHSSVFG-------QHESGSGHSSAYSQHGSGS------------------ 1774
               P + R   S VF        +  SG+G S    +  S                    
Sbjct: 1188 SPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEE 1247

Query: 1775 ------GHFCSQGQHGSTSGQSSTFDQE---GSSTGQSSSHGQHGSGSSQSSSYGQQGSG 1825
                   H  S+ +  STS   S+ + E     S     S  Q    + +  S      G
Sbjct: 1248 PAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGG 1307

Query: 1826 SGQSPSRGRHGSGSGHSSSYGQ----HGSG-------SGWSSSSGRHGSG---------- 1864
               SP      +     +S+G       SG       +G+SS      +G          
Sbjct: 1308 PHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDP 1367

Query: 1865 ----SGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYE--------QHGSRSGQSSRGEQ 1912
                  QS+    H SS        + G  S  S S              RS  +S  E 
Sbjct: 1368 SLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEM 1427

Query: 1913 HGSSSGSSSSYGQHGS--GSRQSLGHGQHGSGSGQSP-------SPSRGRHGSGSGQSSS 1963
                  + S   + GS  G R   G     S SG SP       +PSRGR    S     
Sbjct: 1428 KDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPK 1487

Query: 1964 YGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSAS 2023
              P    +    SR P  S   ++  L  +  RSG  S   Q   +    +  GQ  S S
Sbjct: 1488 ALPQ---TPRPRSRSP-SSPELNNKCLTPQRERSGSESSVDQKTVAR---TPLGQR-SRS 1539

Query: 2024 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG-RQGSGSGQSPGHGQRGSGSRQSPSYG 2082
            G S       ++S Q  S       S   +    RQ S SG SP   +  S SR SP   
Sbjct: 1540 GSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSP---EVDSKSRLSPRRS 1596

Query: 2083 RHGSGS-----------GRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSS 2131
            R GS              +S S     P             S   S        GS  + 
Sbjct: 1597 RSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTE 1656

Query: 2132 GYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSG 2191
               +H  +S  + RG R      + SR       SR S    R+   S  S  R    S 
Sbjct: 1657 SSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRS--RSASSSP 1714

Query: 2192 SGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQG 2251
               S +  +H      SS     +SRS               SS  ++  S  G   S  
Sbjct: 1715 ETRSRTPPRHRRSPSVSSPEPAEKSRSSRRR--------RSASSPRTKTTSRRGRSPSPK 1766

Query: 2252 QHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGH 2311
              G    +S +  ++  +T +        SGSSQS+S  +Q S S    +R R G    H
Sbjct: 1767 PRGLQRSRSRSRREKTRTTRRRDR-----SGSSQSTSRRRQRSRSRSRVTRRRRGGSGYH 1821

Query: 2312 SSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHG 2371
            S S  +  S    S +S R   G  ++       S S  S    +        +++ +  
Sbjct: 1822 SRSPARQES----SRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSR 1877

Query: 2372 SRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSL 2404
            SR+   SR      S   +S   +  S SR S+
Sbjct: 1878 SRTPLISRRR----SRSRTSPVSRRRSRSRTSV 1906



 Score =  123 bits (308), Expect = 3e-27
 Identities = 416/1788 (23%), Positives = 573/1788 (32%), Gaps = 280/1788 (15%)

Query: 915  RSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQS-----SR 969
            RS SS         S    H+S S       +  +      S ++   RS  +     SR
Sbjct: 199  RSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSR 258

Query: 970  SEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS------GQSSS 1023
                 +S+ S+SS     S SR +       + +G+SPSP+ GR G G       G +S+
Sbjct: 259  RAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTST 318

Query: 1024 YGPYRSGSGWSSSRGPYE-SGSGHSSGLGHRESRSGQSSGYG------------QHGSSS 1070
              P    +       PYE            R S S + S  G            +HG S 
Sbjct: 319  QRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSP 378

Query: 1071 GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSS-------GYGRQGSGSG 1123
               +T           S        S   S      S SS+SS          R  S S 
Sbjct: 379  QPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSP 438

Query: 1124 QSPGHGQRGSGSRQSPSYGRHGS-GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ 1182
            +SP         + +P+ G H    S  +S +  HG    + S         G+S S + 
Sbjct: 439  ESP---------KPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPAT 489

Query: 1183 HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHS 1242
               G   S    + G    +S +  R    S S+  +G+  S S Q  G  R     G S
Sbjct: 490  AKRGRSRSRTPTKRGHSRSRSPQWRR----SRSAQRWGR--SRSPQRRGRSRSPQRPGWS 543

Query: 1243 PSRGRHGSGLGHSSSHGQHGSGS----GRSSSRGPYESRSGHSSVFGQHESGS------- 1291
             SR     G   S+  G+  S S    GRS SR P       S    +  S S       
Sbjct: 544  RSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRR 603

Query: 1292 GHSSAYSQHGSGSGHFCSQGQHGSTS--GQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGY 1349
              S   ++ G       ++ +  + S   + S        +G+S S      G S+S   
Sbjct: 604  SRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTP 663

Query: 1350 GRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSW 1409
             R G    ++P+R    SG   S +  + G     +   GR  S S    G  H  S + 
Sbjct: 664  ARRGRSRSRTPAR---RSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSH--SRTP 718

Query: 1410 QSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQH 1469
            Q  G +   S   + S   Q  SRS  S   ++   SS  S S     S ++  L   + 
Sbjct: 719  QRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRS 778

Query: 1470 GSGSGQSPS------PSRGRHGSGSGQSSSYSP----YGSGSGWSSSRGPYESGSSHSSG 1519
             SGS   P       P R R GS   ++ S +P      S S     +    S  SHSS 
Sbjct: 779  LSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSS 838

Query: 1520 LGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSG-QSSSHGQHGSG 1578
              H + +SG     G        +S      S + Q  SC +       +S +  +H   
Sbjct: 839  SPHPKVKSGTPPRQG------SITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRH--- 889

Query: 1579 SSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFG 1638
                       S SG SP   +  +  RQSPS         RSSS       +       
Sbjct: 890  -----------SCSGSSPPRVKSSTPPRQSPS---------RSSSPQPKVKAIISPRQRS 929

Query: 1639 HHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQ 1698
            H  SSS   S  +   +            SRS            SR   RY   GS S  
Sbjct: 930  HSGSSSPSPSRVTSRTT---------PRRSRSVSPC----SNVESRLLPRYSHSGSSSPD 976

Query: 1699 SSGHGRQGSGSGQSPSRGRH-GSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQH 1757
            +           ++P R  H GS   +     Q   G   S S+ P        S+    
Sbjct: 977  T-------KVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLV--- 1026

Query: 1758 ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSS 1817
                       Q   GS   C+  +  +  G+S          GQS +   H S +S S 
Sbjct: 1027 -----------QSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTS-SP 1074

Query: 1818 SYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESS 1877
               Q  S S    S+ +     G S S          SS      S S      G   +S
Sbjct: 1075 EVRQSHSESPSLQSKSQTSPKGGRSRS----------SSPVTELASRSPIRQDRGEFSAS 1124

Query: 1878 SWQSSGYTQHGSG-SGHSSSYEQHGSRS--GQSSRGEQHGSSSGSSSSYGQHGSGS--RQ 1932
                SG +   S     SSSY    S S  GQ SR E   S    +    +  + S  RQ
Sbjct: 1125 PMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQ-SRLETAESKEKMALPPQEDATASPPRQ 1183

Query: 1933 SLGHGQHGSGSGQSPSPSRGR-HGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLG 1991
                         SP P + R   S   + +   P    SG  SS    E  S   +   
Sbjct: 1184 K---------DKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQ 1234

Query: 1992 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSC---GQHGASSGQSSSHGQHGSG 2048
              E            G    H S+  +  S S   SS     +   S     S  Q    
Sbjct: 1235 DEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLE 1294

Query: 2049 SSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG-----RHGSGSGRSSSSG-------- 2095
            + +         G   SP H +  +   +  S+G     R+    G   ++G        
Sbjct: 1295 AVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKED 1354

Query: 2096 QHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG--------- 2146
             +GP L +       +    QS+  S H S         + G  S QS            
Sbjct: 1355 LNGPFLNQLETDPSLDMKE-QSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRT 1413

Query: 2147 -ERHGSSSGSS-----------SRYGQHGS------GSRQSSGHGRQGSGSG-----HSP 2183
              R  SSS SS           SR  + GS      GS   S H   GS  G      +P
Sbjct: 1414 PSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTP 1473

Query: 2184 SRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSG 2243
            SRGR       SS   +    + R  SR P      +  +  Q E     SS   +  + 
Sbjct: 1474 SRGR---SECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVAR 1530

Query: 2244 SGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGS-----------SQSSSYGQQ 2292
            +      GQ  S SG S   D + S++ Q  S       S           S+S S  + 
Sbjct: 1531 T----PLGQR-SRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEV 1585

Query: 2293 GSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 2352
             S S  SP R R GS                 S SS    + + ++        SS +  
Sbjct: 1586 DSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGR 1645

Query: 2353 GYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 2412
            G +  GS S  SS   +H  +S  + RG R      + S        SR           
Sbjct: 1646 GPSPEGSSSTESS--PEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSR----------- 1692

Query: 2413 SGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2472
               SP  +R    S   +S+S SP       + SR P            HR S S  S  
Sbjct: 1693 --SSPELTRKARLSRRSRSASSSPE------TRSRTPPR----------HRRSPSVSSPE 1734

Query: 2473 YGQHGSSS----GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQ--------HGSGSS 2520
              +   SS      SS   +  S  G+S S    G    +S S  +          SGSS
Sbjct: 1735 PAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSS 1794

Query: 2521 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHG 2568
            QS+   RQ S S       +RG     S S  R    S R+SS  + G
Sbjct: 1795 QSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPAR--QESSRTSSRRRRG 1840



 Score =  115 bits (287), Expect = 8e-25
 Identities = 425/1763 (24%), Positives = 582/1763 (33%), Gaps = 240/1763 (13%)

Query: 1171 ESSSGQSSSYSQHGSGSGHSSGYGQHGS----RSGQSSRGERHGSSSGSSS--HYGQHGS 1224
            ESSS +S +  Q         G     S       +SS+ ++H S S S    H      
Sbjct: 176  ESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPK 235

Query: 1225 GSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF 1284
              R+S    R+ S S     + R      H S+     S S  S SR    +   H++  
Sbjct: 236  SKRKSKDKKRKRSRSTTPAPKSRRA----HRSTSADSASSSDTSRSRSRSAAAKTHTTAL 291

Query: 1285 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSS 1344
                +G   S A  + G G   F    + G+TS Q  +   E ++   SS Y  +     
Sbjct: 292  ----AGRSPSPASGRRGEGDAPF---SEPGTTSTQRPS-SPETATKQPSSPYEDKDKDKK 343

Query: 1345 QSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 1404
            + S        +  SPS  R  +G    +         G  S      +   Q       
Sbjct: 344  EKSA-------TRPSPSPERSSTGPEPPAPTPLLAERHG-GSPQPLATTPLSQEPVNPPS 395

Query: 1405 ESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSS----SYGQH---- 1456
            E+S  +     +       SSS E     S Q ++  RH SSS  S     + G H    
Sbjct: 396  EASPTRDRSPPKSPEKLPQSSSSES-SPPSPQPTKVSRHASSSPESPKPAPAPGSHREIS 454

Query: 1457 GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSH 1516
             S + ++  HG+       S +PSR           S SP  +  G S SR P + G S 
Sbjct: 455  SSPTSKNRSHGRAKRDKSHSHTPSRR-------MGRSRSPATAKRGRSRSRTPTKRGHSR 507

Query: 1517 SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG-STSGQSSSCGQ-HGASSGQSSSHGQ 1574
            S     R SRS Q  G  +     G S +  + G S S  +   G+   A  G+S S   
Sbjct: 508  SRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSP 567

Query: 1575 HGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGES 1634
               G S+S    R+G    ++P   +R S SR +P+  R      RS +  + G     +
Sbjct: 568  ATRGRSRSRTPARRGRSRSRTPA--RRRSRSR-TPTRRR-----SRSRTPARRGRSRSRT 619

Query: 1635 SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGS 1694
                   + S                    +  +R G+S R        RS SR     S
Sbjct: 620  PARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRS-RSRTPARRGRSRSRTPARRS 678

Query: 1695 GSRQSSGHGRQGSGSGQSPSRGRHGS------GLGHSSS---HGQHGSGSGRS--SSRGP 1743
            G  +S    R+G    ++P RGR  S      G  HS +    G+ GS S R   S    
Sbjct: 679  GRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQ 738

Query: 1744 YESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQS 1803
              SRS  S    +    S  S + S   S +    S  +  S SG S    Q+  +  + 
Sbjct: 739  RRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR--SLSGSSPCPKQKSQTPPRR 796

Query: 1804 SSHGQ-HGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHG 1862
            S  G       S++     + S S     + +  S   HSSS       SG     G   
Sbjct: 797  SRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSIT 856

Query: 1863 SGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSS 1922
            S             S ++SS   +  S +    S         +SS   +   S  SS  
Sbjct: 857  SPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQ 916

Query: 1923 YGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYES 1982
                   S +   H    SGS  SPSPSR    +   +S S  P    S   S   P  S
Sbjct: 917  PKVKAIISPRQRSH----SGSS-SPSPSRVTSRTTPRRSRSVSPC---SNVESRLLPRYS 968

Query: 1983 GSGHSSG-------LGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGAS 2035
             SG SS           R+S SG  S Y +  + +          S SG  S C Q    
Sbjct: 969  HSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGP------SLSGSKSPCPQE--K 1020

Query: 2036 SGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSG 2095
            S  S      GS S  +      G  S   PG    G  S Q           G+S +S 
Sbjct: 1021 SKDSLVQSCPGSLSLCA------GVKSSTPPGESYFGVSSLQL---------KGQSQTSP 1065

Query: 2096 QH-----GPGLGESSGFGHHESSSGQSSSY-SQHGSGSGHSSGYGQHGSRSG-QSSRGER 2148
             H      P + +S    H ES S QS S  S  G  S  SS   +  SRS  +  RGE 
Sbjct: 1066 DHRSDTSSPEVRQS----HSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEF 1121

Query: 2149 HGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRS 2208
              S    S    +       SS +    S S    SR          +   Q  + +   
Sbjct: 1122 SASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPP 1181

Query: 2209 SSRG-----PYESRSGHSSVFG-------QHESGSGHSSAYSQHGSGS------------ 2244
              +      P + R   S VF        +  SG+G S    +  S              
Sbjct: 1182 RQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEV 1241

Query: 2245 ------------GHFCSQGQHGSTSGQSSTFDQE---GSSTGQSSSHGQHGSGSSQSSSY 2289
                         H  S+ +  STS   S+ + E     S     S  Q    + +  S 
Sbjct: 1242 VEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSM 1301

Query: 2290 GQQGSGSGQSPSRGRHGSGSGHSSSYGQ----HGSGS-GWSSSSGRHGSGSGQSSG-FGH 2343
                 G   SP      +     +S+G       SG  G   ++G         +G F +
Sbjct: 1302 ASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLN 1361

Query: 2344 HESSSWQSSGYTQHGSGSGHSSS------YEQHGSRSGQSSRG----------ERHGSSS 2387
               +        Q    SGHSSS       E+ G  S QS              R  SSS
Sbjct: 1362 QLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSS 1421

Query: 2388 GSS-----------SSYGQHGS--GSRQSLGHGQHGSGSGQSP-------SPSRGRHGSG 2427
             SS           S   + GS  G R   G     S SG SP       +PSRGR    
Sbjct: 1422 ASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECD 1481

Query: 2428 SGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG 2487
            S       P    +    SR P  S   ++  L  +  RSG  S   Q   +    +  G
Sbjct: 1482 SSPEPKALPQ---TPRPRSRSP-SSPELNNKCLTPQRERSGSESSVDQKTVAR---TPLG 1534

Query: 2488 QHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG-RQGSGSGQSPGHGQRGSGSR 2546
            Q  S SG S       ++S Q  S       S   +    RQ S SG SP   +  S SR
Sbjct: 1535 QR-SRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSP---EVDSKSR 1590

Query: 2547 QSPSYGRHGSG-----SGRSSSSGQHGSGLGESSGFGH-----HESSSGQSSSY---SQH 2593
             SP   R GS        R++   Q GS                 S SG SS     S  
Sbjct: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE 1650

Query: 2594 GSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSP 2653
            GS S  SS   +H  +S  + RG R      + S        SR S    R+   S +S 
Sbjct: 1651 GSSSTESSP--EHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRS- 1707

Query: 2654 SRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSG 2713
             R    S    S +  +H      SS     +SR                SS  ++  S 
Sbjct: 1708 -RSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRR--------RSASSPRTKTTSR 1758

Query: 2714 SGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHG 2773
             G   S    G    +S +  ++  +T +        SGSSQS+   R  + S   ++  
Sbjct: 1759 RGRSPSPKPRGLQRSRSRSRREKTRTTRRRDR-----SGSSQSTSRRRQRSRSRSRVTRR 1813

Query: 2774 RHGSGSGQSSSYGQHGSGSGQSS 2796
            R G GSG  S        S  SS
Sbjct: 1814 RRG-GSGYHSRSPARQESSRTSS 1835



 Score =  114 bits (286), Expect = 1e-24
 Identities = 429/1845 (23%), Positives = 593/1845 (32%), Gaps = 280/1845 (15%)

Query: 104  DTHQHQEEQEETEKEENKRQESSFSHS-SWSAGENDSYSRNVRGSLKPGTESISRRLSFQ 162
            +THQ  E  E+    +N+R  ++F  S S+  G +    R  R + +P  E         
Sbjct: 120  ETHQLAELNEK----KNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEP-------P 168

Query: 163  RDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQ----SPNYGQHGSGSGQSSSN 218
            + +S    S S +S +  ++     +  GR    S   +    S    +H S S   S  
Sbjct: 169  KPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSES--ESKK 226

Query: 219  DTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSG 278
              H S + +S   S+ K      S      S   H S      + S  SS   R RS S 
Sbjct: 227  RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRST----SADSASSSDTSRSRSRSA 282

Query: 279  SSSSYGQHGSGSRQSLGHGRQGSGSR-------------QSPSHVRHGSGSGHSSSHGQH 325
            ++ ++    +G   S   GR+G G                SP        S +       
Sbjct: 283  AAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDK 342

Query: 326  GSGSSYSYSRGHYESGSG-----QTSGFGQHESGSGQ---SSGYSKHGSGSGHSSSQGQH 377
               S+   S     S +G      T    +   GS Q   ++  S+        +S  + 
Sbjct: 343  KEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRD 402

Query: 378  GSTSGQ-----ASSSGQHGSSSRQSSSYGQHESASRHS----SGRGQHSSGSGQSPGHGQ 428
             S          SSS +    S Q +   +H S+S  S       G H   S  SP    
Sbjct: 403  RSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREIS-SSPTSKN 461

Query: 429  RGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHS 488
            R  G  +   S  H        S  P  +  G S      +     S       S S   
Sbjct: 462  RSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQR 521

Query: 489  SGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPS---R 545
             G  +   R G+S   +R G S   ++        +R+   HSR  +  G+S S +   R
Sbjct: 522  WGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARR 581

Query: 546  GRHES---GSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGS 602
            GR  S     R+S S  P      RS SR P   G   S     + SR+           
Sbjct: 582  GRSRSRTPARRRSRSRTP---TRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSR 638

Query: 603  SSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSH-GQHGSGSSQSSRYGQQGSGSGQSPS 661
            S    S   +  + + +  S  +  A  G+S S      SG S+S    ++G    ++P 
Sbjct: 639  SPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPR 698

Query: 662  RGRHGSDF----GHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHG 717
            RGR  S      G S S      G   SSS   + S + Q     + S   + S  S   
Sbjct: 699  RGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRR 758

Query: 718  SGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHG-RQGSGSGHSP 776
            S S  S        RS   SR     S SG S    Q      + S  G  Q      +P
Sbjct: 759  SRSLSS-------PRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTP 811

Query: 777  SRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASG 836
             R    SSS       +  S  S SSS  H +  SG                        
Sbjct: 812  PRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSG------------------------ 847

Query: 837  HFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQR 896
               +  R GS +  S  + +   +  + S +         +    RH S SG SP   + 
Sbjct: 848  ---TPPRQGSIT--SPQANEQSVTPQRRSCFESSPDPELKSRTPSRH-SCSGSSPPRVKS 901

Query: 897  GSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSS 956
             +   QSPS         ++  S R  S SG SS    + +S  +   ++  S   +  S
Sbjct: 902  STPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVES 961

Query: 957  -----YEQHGSRSGQSS---RSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS 1008
                 Y   GS S  +     +    S SGS S Y +     +     G   SGS +SP 
Sbjct: 962  RLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPK----VKAQTPPGPSLSGS-KSPC 1016

Query: 1009 PSR-----------GRHGSGSGQSSSYGPYRSGSGWSS--SRGPYESGSGHSSGL----- 1050
            P             G     +G  SS  P  S  G SS   +G  ++   H S       
Sbjct: 1017 PQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEV 1076

Query: 1051 --GHRESRSGQS-SGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGAS----SGQSSSHG 1103
               H ES S QS S     G  S  SS   +  S S      G+  AS    SG S    
Sbjct: 1077 RQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQS 1136

Query: 1104 QHGSGSSQSSGYGRQGSGS--GQS--------------PGHGQRGSGSRQSPSYG----- 1142
            +     S SS Y    S S  GQS              P      S  RQ   +      
Sbjct: 1137 RF---QSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQ 1193

Query: 1143 -----------------RHGSGSGRSSSSGQHGSGLGESSG-------FGHHESSSGQ-- 1176
                             R  SG+G S  + +  S L  SS            E  +GQ  
Sbjct: 1194 DRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQIL 1253

Query: 1177 ---SSSYSQHGSGSGHSSGYGQHG-------SRSGQSSRGERHGSSSGSSSHYGQHGSGS 1226
               SS   +  + +  SS   +          +S   +  E     S +SS  G H S  
Sbjct: 1254 SHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPE 1313

Query: 1227 RQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQ 1286
             +   +      S  SP   R+   LG   + G   S   +    GP+ ++         
Sbjct: 1314 HKELSNSPLRENSFGSPLEFRNSGPLGTEMNTG--FSSEVKEDLNGPFLNQLETDPSLDM 1371

Query: 1287 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQS 1346
             E  S  SS +S            G   + S  S   D    +  +  S     S     
Sbjct: 1372 KEQ-STRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERS--SSASSPEMK 1428

Query: 1347 SGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGW-----SSSSGRHGSGSGQSSGF 1401
             G  R  +   +S S      GSG  S +   GS  G      + S GR    S      
Sbjct: 1429 DGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKA 1488

Query: 1402 --------GHHESSSWQSSGC-TQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSS 1452
                        SS   ++ C T     SG  SS +Q      ++  G+R  S SGSS  
Sbjct: 1489 LPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQ--KTVARTPLGQR--SRSGSSQE 1544

Query: 1453 YGQHGSGSRQSLGHGQHGSGS-GQSPSPSRGRHGSGSG----QSSSYSPYGSGSGWSSS- 1506
                 S S Q          S  ++ +P R R  SGS       S  SP  S SG S   
Sbjct: 1545 LDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEV 1604

Query: 1507 -----RGPYESGSSHSSGLGH--------RESRSGQSS---GYGQHGSSSGHSSTH---- 1546
                   P     S SS            R SRSG SS   G    GSSS  SS      
Sbjct: 1605 KDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPK 1664

Query: 1547 ---GQHGSTSG-------------QSSSCGQHGASSGQSSSHGQHGSGSSQSSG-----Y 1585
                + GS S              +SS          + S   +  S S ++       +
Sbjct: 1665 SRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRH 1724

Query: 1586 GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 1645
             R  S S   P    R S  R+S S  R  + S R  S      GL  S      E +  
Sbjct: 1725 RRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKT-- 1782

Query: 1646 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSS---SRSSSRYGQHGSGSRQSSGH 1702
              ++  +  SGS  S+   +  SRS       R G S   SRS +R     + SR+  G 
Sbjct: 1783 -RTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGR 1841

Query: 1703 GRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESR 1747
             R    S +  SR R        S      +   RS SR P  SR
Sbjct: 1842 SRTPPTS-RKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISR 1885



 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 133/520 (25%), Positives = 181/520 (34%), Gaps = 74/520 (14%)

Query: 120  NKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSY 179
            ++ + SS S      G   + SR  R    PG           RD SG  + +S   SS 
Sbjct: 1415 SRERSSSASSPEMKDGLPRTPSRRSRSGSSPGL----------RDGSGTPSRHSLSGSSP 1464

Query: 180  GEQNSDSHQSSGRGQCGSGS-----GQSPNYGQHGSGSGQSSSN--DTHGSGSGQSSGFS 232
            G ++     S GR +C S        Q+P        S + ++         SG  S   
Sbjct: 1465 GMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVD 1524

Query: 233  QH---KSSSGQ--SSGYSQHGSGSGHSSGYGQHGSRSGQSSRGE-----RHRSSSGSSSS 282
            Q    ++  GQ   SG SQ       +S   +  S S   S+ +     R RS SGSS  
Sbjct: 1525 QKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSP- 1583

Query: 283  YGQHGSGSRQSLGHGRQGSGS--RQSPSHVRHGSGSGHSSSH----------GQHGSGSS 330
              +  S SR S    R GS    +  P           SS             +  SGSS
Sbjct: 1584 --EVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSS 1641

Query: 331  YSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSG-----HSSSQGQHGSTSGQAS 385
             S  RG    GS  T    +H       S  ++ GS S       S +  +  S+     
Sbjct: 1642 -SKGRGPSPEGSSSTESSPEHP----PKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPE 1696

Query: 386  SSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTG 445
             + +   S R  S+    E+ SR      +  S S   P    R S   +S SS +  T 
Sbjct: 1697 LTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTT 1756

Query: 446  FGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGE 505
              R  S  P   G   S      E +    +   +  SGS  S+   +  SRS       
Sbjct: 1757 SRRGRSPSPKPRGLQRSRSRSRREKT---RTTRRRDRSGSSQSTSRRRQRSRSRSRVTRR 1813

Query: 506  RQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHES--------GSRQSSS 557
            R+G S   S S  +  S SR S   SR   G  ++P  SR R  S         SR  +S
Sbjct: 1814 RRGGSGYHSRSPARQES-SRTS---SRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRAS 1869

Query: 558  YGPHGYGSGRSSSRGPYES---GSGHSSGLGHQESRSGQS 594
               H     RS SR P  S       +S +  + SRS  S
Sbjct: 1870 PATH----RRSRSRTPLISRRRSRSRTSPVSRRRSRSRTS 1905



 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 88/327 (26%), Positives = 115/327 (35%), Gaps = 52/327 (15%)

Query: 630  SGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSS-------------YG 676
            S  S S        S SSR GQ  S S   P++ +  S    + S              G
Sbjct: 2412 SAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAG 2471

Query: 677  QHGSGSG----WSSSNGPH-GSVSGQSSGFGHKS-GSGQSSGYSQHGSGSSHSSGYRKHG 730
                 SG     +SS G H G +S  + G  H   G   +S  +Q  S  +     ++  
Sbjct: 2472 SQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERR 2531

Query: 731  SRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHG-----------------------R 767
            S S  SS S    SSS  SSS    GS S  S G                         R
Sbjct: 2532 SSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVR 2591

Query: 768  QGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQG 827
            +G     +P++ +  SSS  SSS     S +S SSS     S S  +S      S S   
Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS-SSSSSSSSSSSSSSSSSSPS 2650

Query: 828  YSQHG------SASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRG 881
             ++ G       AS      G   S S +       DS S  S S  +    S   S R 
Sbjct: 2651 PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRS-LSYSPVERRRPSPQPSPRD 2709

Query: 882  RHGSGSGQSPGHGQRGSGSGQSPSYGR 908
            +  S S +    GQR  G  +SPS+ R
Sbjct: 2710 QQSSSSERGSRRGQR--GDSRSPSHKR 2734



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 69/259 (26%), Positives = 91/259 (35%), Gaps = 26/259 (10%)

Query: 1379 GSGSGWSSSSGRH-GSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQS 1437
            G+ +  +SS+G H G  S  + G  H +     +S   Q  S        ++  S S  S
Sbjct: 2478 GAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSS 2537

Query: 1438 SRGERHGSSSGSSSSYGQHGSGSRQSLGHG---------------------QHGSGSGQS 1476
            S      SSS SSSS    GS S  S G                           G    
Sbjct: 2538 SSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPE 2597

Query: 1477 PSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQH 1536
            P+P++ +  S S  SSS S   S S  SSS     S SS SS      S S   +  G  
Sbjct: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ 2657

Query: 1537 GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHG--QHGSGSSQSSGYGRQGSGSGQ 1594
                  S      G    +S           +S S+   +    S Q S   +Q S S +
Sbjct: 2658 ALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSER 2717

Query: 1595 SPGHGQRGSGSRQSPSYGR 1613
                GQRG    +SPS+ R
Sbjct: 2718 GSRRGQRGDS--RSPSHKR 2734



 Score = 52.4 bits (124), Expect = 6e-06
 Identities = 68/259 (26%), Positives = 90/259 (34%), Gaps = 26/259 (10%)

Query: 2319 GSGSGWSSSSGRH-GSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQS 2377
            G+ +  +SS+G H G  S  + G  H +     +S   Q  S        ++  S S  S
Sbjct: 2478 GAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSS 2537

Query: 2378 SRGERHGSSSGSSSSYGQHGSGSRQSLGHG---------------------QHGSGSGQS 2416
            S      SSS SSSS    GS S  S G                           G    
Sbjct: 2538 SSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPE 2597

Query: 2417 PSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQH 2476
            P+P++ +  S S  SSS S   S S  SSS     S S  SS      S S   +  G  
Sbjct: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ 2657

Query: 2477 GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHG--QHGSGSSQSSGYGRQGSGSGQ 2534
                  S      G    +S           +S S+   +    S Q S   +Q S S +
Sbjct: 2658 ALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSER 2717

Query: 2535 SPGHGQRGSGSRQSPSYGR 2553
                GQRG    +SPS+ R
Sbjct: 2718 GSRRGQRGDS--RSPSHKR 2734



 Score = 52.0 bits (123), Expect = 8e-06
 Identities = 88/326 (26%), Positives = 107/326 (32%), Gaps = 40/326 (12%)

Query: 2205 SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGS------GSGHFCSQGQHGSTSG 2258
            S  S SR   E     SS  GQ  S S    A  Q  S           C   Q    +G
Sbjct: 2412 SAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAG 2471

Query: 2259 QSSTFDQEGSSTGQSSSHGQHGS--------------GSSQSSSYGQQGSG-SGQSPSRG 2303
              S     G+    +SS G H                G   +S+  QQ S  +   P++ 
Sbjct: 2472 SQSL--SSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKE 2529

Query: 2304 RHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSG----------FGHHESSSWQSSG 2353
            R  S S  SSS     S S  SSSS   GS S  S G               S +     
Sbjct: 2530 RRSSSSSSSSSSSSSSSSSS-SSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKE 2588

Query: 2354 YTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 2413
              + G     + +  +  S S  SS      SSS SSSS     S S  S       S S
Sbjct: 2589 AVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---SSSSSSS 2645

Query: 2414 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYES---GSGHSSGLGHRESRSGQS 2470
              SPSP++    +    +S   P        S R P +S       S     R   S Q 
Sbjct: 2646 SSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQP 2705

Query: 2471 SGYGQHGSSSGHSSTHGQHGSTSGQS 2496
            S   Q  SSS   S  GQ G +   S
Sbjct: 2706 SPRDQQSSSSERGSRRGQRGDSRSPS 2731



 Score = 52.0 bits (123), Expect = 8e-06
 Identities = 66/257 (25%), Positives = 84/257 (32%), Gaps = 18/257 (7%)

Query: 845  GSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGS--GQSPGHGQRGSGSGQ 902
            G+ +  +SS+G H+      +    H       +  G     +     P   +R S S  
Sbjct: 2478 GAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSS 2537

Query: 903  SPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHG- 961
            S S     S S  SSSS    SGS  S   G            +  S +       + G 
Sbjct: 2538 SSS---SSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGR 2594

Query: 962  ---------SRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG 1012
                      R   SS S    SSS SSSS     S S  S       S S  SPSP++ 
Sbjct: 2595 PPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP 2654

Query: 1013 RHGSGSGQSSSYGPYRSGSGWSSSRGPYES---GSGHSSGLGHRESRSGQSSGYGQHGSS 1069
               +    +S   P        S R P +S       S     R   S Q S   Q  SS
Sbjct: 2655 GPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSS 2714

Query: 1070 SGHSSTHGQHGSTSGQS 1086
            S   S  GQ G +   S
Sbjct: 2715 SERGSRRGQRGDSRSPS 2731



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 67/259 (25%), Positives = 89/259 (34%), Gaps = 26/259 (10%)

Query: 1849 GSGSGWSSSSGRH-GSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQS 1907
            G+ +  +SS+G H G  S  + G  H +     +S   Q  S        ++  S S  S
Sbjct: 2478 GAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSS 2537

Query: 1908 SRGEQHGSSSGSSSSYGQHGSGSRQSLGHG---------------------QHGSGSGQS 1946
            S      SSS SSSS    GS S  S G                           G    
Sbjct: 2538 SSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPE 2597

Query: 1947 PSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQH 2006
            P+P++ +  S S  SSS     S S  SSS     S S  SS      S S   +  G  
Sbjct: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ 2657

Query: 2007 GSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHG--QHGSGSSQSSGYGRQGSGSGQ 2064
                  S      G    +S           +S S+   +    S Q S   +Q S S +
Sbjct: 2658 ALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSER 2717

Query: 2065 SPGHGQRGSGSRQSPSYGR 2083
                GQRG    +SPS+ R
Sbjct: 2718 GSRRGQRGDS--RSPSHKR 2734



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 87/345 (25%), Positives = 113/345 (32%), Gaps = 31/345 (8%)

Query: 1902 SRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQS 1961
            SR+  S+  +   +S  + S   + G    QSL          +SP PS     S    +
Sbjct: 2407 SRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLL--PPAQDQPRSPVPSAFSDQSRCLIA 2464

Query: 1962 SSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS 2021
             +    GS S  S +     S +G  +G+    +     S  G+  +S+G      Q  S
Sbjct: 2465 QTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTG-----AQQPS 2519

Query: 2022 ASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHG---QRGSGSRQS 2078
            A        +  +SS  SSS     S SS SS     GS S  S G     Q     ++ 
Sbjct: 2520 ALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRV 2579

Query: 2079 PSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS 2138
            PS       + R     +  P   +        SSS  SSS S   S S  SS       
Sbjct: 2580 PSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSS------- 2632

Query: 2139 RSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSH 2198
                        SSS SSS      S S   +  G Q      SP +   G     S   
Sbjct: 2633 ------------SSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRK 2680

Query: 2199 GQHGSGSGRSSSRGPYESR--SGHSSVFGQHESGSGHSSAYSQHG 2241
                    RS S  P E R  S   S   Q  S S   S   Q G
Sbjct: 2681 PIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRG 2725



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 84/321 (26%), Positives = 103/321 (32%), Gaps = 30/321 (9%)

Query: 1265 SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGS------GSGHFCSQGQHGSTSG 1318
            S  S SR   E     SS  GQ  S S    A  Q  S           C   Q    +G
Sbjct: 2412 SAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAG 2471

Query: 1319 QSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQH 1378
             S +      +T  SS+  H G  S  + G      G   + +  +  S         + 
Sbjct: 2472 -SQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKER 2530

Query: 1379 GSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCT----------QHGSGSGHSSSYE 1428
             S S  SSSS    S S  SS      SSS  S G +          +  S +       
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590

Query: 1429 QHG----------SRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS 1478
            + G           R   SS      SSS SSSS     S S  S       S S  SPS
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650

Query: 1479 PSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYES---GSSHSSGLGHRESRSGQSSGYGQ 1535
            P++    +    +S   P        S R P +S     S S     R   S Q S   Q
Sbjct: 2651 PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ 2710

Query: 1536 HGSSSGHSSTHGQHGSTSGQS 1556
              SSS   S  GQ G +   S
Sbjct: 2711 QSSSSERGSRRGQRGDSRSPS 2731



 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 91/367 (24%), Positives = 122/367 (33%), Gaps = 44/367 (11%)

Query: 2431 SSSYSPYGSGSGWSSSRGP---YESGSGHSSG--LGHRESRSGQSSGYGQHGSSSGHSST 2485
            S+  +P  SG+  +S R P   YE  SG +S   L    SR+  S+      +S    S 
Sbjct: 2368 SARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSP 2427

Query: 2486 HGQHGSTSGQSS-SCGQHGASSGQSSSHGQHGS---------GSSQSSGYGRQGSGSGQS 2535
              + G    QS     Q    S   S+                 SQS   G   + +  +
Sbjct: 2428 SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSA 2487

Query: 2536 PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGS 2595
              H   G  S  +P       G   +S+  Q  S L          SSS  SSS S   S
Sbjct: 2488 GDHN--GMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSS 2545

Query: 2596 GSGHSSGYGQHGSRSGQSSRG----------ERHGSSSGSSSHYGQHGS------GSRQS 2639
             S  SS     GS S  S             +R  S + +     + G         R+ 
Sbjct: 2546 SSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKR 2605

Query: 2640 SGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVF----- 2694
                   S S  S S     S    SSS     S S  SSS  P  ++ G  ++      
Sbjct: 2606 RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASP 2665

Query: 2695 -----GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHR 2749
                 G+  S S      S   S S  + S  +    S Q S  DQ+ SS+ + S  G R
Sbjct: 2666 KKPPPGERRSRSPRKPIDSLRDSRSLSY-SPVERRRPSPQPSPRDQQSSSSERGSRRGQR 2724

Query: 2750 GSGSSQS 2756
            G   S S
Sbjct: 2725 GDSRSPS 2731



 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 77/279 (27%), Positives = 94/279 (33%), Gaps = 52/279 (18%)

Query: 1444 GSSSGSSSSYGQHG---SGSRQSLGHGQHG----SGSGQSPS------PSRGRHGSGSGQ 1490
            G+ + ++SS G H    S     + H   G    S   Q PS      P++ R  S S  
Sbjct: 2478 GAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSS 2537

Query: 1491 SSSYSPYGSGSGWSSSRGPYESGSSHSSGLGH------------------------RESR 1526
            SSS S   S S  SSS     SGSS S   G                         RE R
Sbjct: 2538 SSSSSSSSSSSSSSSSSS---SGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGR 2594

Query: 1527 SGQSS-GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGY 1585
              + +    +  SSS  SS+     S+S  SSS     +SS  SSS     S S   +  
Sbjct: 2595 PPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP 2654

Query: 1586 GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 1645
            G Q      SP     G    +SP   R    S R S S  +                S 
Sbjct: 2655 GPQALPKPASPKKPPPGERRSRSP---RKPIDSLRDSRSLSYSP--------VERRRPSP 2703

Query: 1646 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSR 1684
            Q S   Q  S S   S  GQ G     S +  R   S R
Sbjct: 2704 QPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPR 2742



 Score = 48.5 bits (114), Expect = 9e-05
 Identities = 86/313 (27%), Positives = 107/313 (34%), Gaps = 48/313 (15%)

Query: 910  GSGSGRSSSSGRH-GSGSGQSSGFGHKSSSGQ---SSGYTQHGSGSGHSSSYEQHGSRSG 965
            G+ +  +SS+G H G  S  + G  H S  G+   S+G  Q  + +    + E+  S S 
Sbjct: 2478 GAVATTTSSAGDHNGMLSVPAPGVPH-SDVGEPPASTGAQQPSALAALQPAKERRSSSSS 2536

Query: 966  QSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYG 1025
             SS S    SSS SSSS                  S SG S S S G   S         
Sbjct: 2537 SSSSSSSSSSSSSSSSS------------------SSSGSSSSDSEG---SSLPVQPEVA 2575

Query: 1026 PYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQ 1085
              R  S   + +     G         R+ RS  SS      SSS  SS+     S+S  
Sbjct: 2576 LKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSS------SSSSSSSS-----SSSSS 2624

Query: 1086 SSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHG 1145
            SSS     +SS  SSS     S S   +  G Q      SP     G    +SP   R  
Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSP---RKP 2681

Query: 1146 SGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 1205
              S R S S  +                S Q S   Q  S S   S  GQ G     S +
Sbjct: 2682 IDSLRDSRSLSYSP--------VERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHK 2733

Query: 1206 GERHGSSSGSSSH 1218
              R   S     H
Sbjct: 2734 RRRETPSPRPMRH 2746



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 78/290 (26%), Positives = 101/290 (34%), Gaps = 36/290 (12%)

Query: 1907 SSRGEQHGSSSGSSSSYGQHGSGSRQ-SLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYG 1965
            SS G+ +G  S  +        G    S G  Q  + +   P+  R    S S  SSS  
Sbjct: 2485 SSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS 2544

Query: 1966 PYGSGSGWSSSRGPYESGSGHSS-------GLGHRESRSGQSSGYGQHGSSSGHSSTHGQ 2018
               S S  SSS G   S S  SS        L    S +       + G     +    +
Sbjct: 2545 SSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRK 2604

Query: 2019 HGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQS 2078
              S+S  SSS     +SS  SSS     S SS SS      S S  SP   + G  +   
Sbjct: 2605 RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---SSSSSSSSPSPAKPGPQALPK 2661

Query: 2079 P-SYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHG 2137
            P S  +   G  RS S  +    L +S           +S SYS             +  
Sbjct: 2662 PASPKKPPPGERRSRSPRKPIDSLRDS-----------RSLSYSPV-----------ERR 2699

Query: 2138 SRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGR 2187
              S Q S  ++  SSS   SR GQ G    +S  H R+       P R R
Sbjct: 2700 RPSPQPSPRDQQSSSSERGSRRGQRGDS--RSPSHKRRRETPSPRPMRHR 2747



 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 90/344 (26%), Positives = 110/344 (31%), Gaps = 29/344 (8%)

Query: 962  SRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQS 1021
            SR+  S+ S+   +S  + S   + G    QSL          +SP PS     + S QS
Sbjct: 2407 SRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLL--PPAQDQPRSPVPS-----AFSDQS 2459

Query: 1022 SSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS 1081
                   +    S S       +  SS   H    S  + G          +ST  Q  S
Sbjct: 2460 RCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPS 2519

Query: 1082 TSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSY 1141
                     +  +SS  SSS     S SS SS     GS S  S      GS     P  
Sbjct: 2520 ALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDS-----EGSSLPVQPEV 2574

Query: 1142 G--RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 1199
               R  S +     + + G     +       SSS  SSS S   S S  SS        
Sbjct: 2575 ALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSS------- 2627

Query: 1200 SGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHG 1259
            S  SS      SSS SSS      S S   +  G Q      SP +   G     S    
Sbjct: 2628 SSSSSSSSSSSSSSSSSS------SSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKP 2681

Query: 1260 QHGSGSGRSSSRGPYESR--SGHSSVFGQHESGSGHSSAYSQHG 1301
                   RS S  P E R  S   S   Q  S S   S   Q G
Sbjct: 2682 IDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRG 2725



 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 62/249 (24%), Positives = 81/249 (32%), Gaps = 27/249 (10%)

Query: 215  SSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHR 274
            SS+ D +G  S  + G          +S  +Q  S         +  S S  SS      
Sbjct: 2485 SSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS 2544

Query: 275  SSSGSSSSYGQHGSGSRQSLGHG-----------------------RQGSGSRQSPSHVR 311
            SSS SSSS    GS S  S G                         R+G     +P+  +
Sbjct: 2545 SSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRK 2604

Query: 312  HGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHS 371
              S S  SSS     S SS S S     S S  +S      S S   +           S
Sbjct: 2605 RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPAS 2664

Query: 372  SSQGQHGSTSGQASSSGQHGSSSRQSSSYG--QHESASRHSSGRGQHSSGSGQSPGHGQR 429
              +   G    ++           +S SY   +    S   S R Q SS S +    GQR
Sbjct: 2665 PKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQR 2724

Query: 430  GSGSGQSPS 438
              G  +SPS
Sbjct: 2725 --GDSRSPS 2731



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 86/344 (25%), Positives = 108/344 (31%), Gaps = 29/344 (8%)

Query: 1432 SRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQS 1491
            SR+  S+  +   +S  + S   + G    QSL          +SP PS     + S QS
Sbjct: 2407 SRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLL--PPAQDQPRSPVPS-----AFSDQS 2459

Query: 1492 SSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS 1551
                   +    S S       ++ SS   H    S  + G          +ST  Q  S
Sbjct: 2460 RCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPS 2519

Query: 1552 TSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSY 1611
                     +  +SS  SSS     S SS SS     GS S  S      GS     P  
Sbjct: 2520 ALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDS-----EGSSLPVQPEV 2574

Query: 1612 G--RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 1669
               R  S +     + + G     +       SSS  SSS S   S S  SS      S 
Sbjct: 2575 ALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2634

Query: 1670 SGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHG 1729
            S  SS      SSS S ++ G              Q      SP +   G     S    
Sbjct: 2635 SSSSSSSSSSSSSSPSPAKPGP-------------QALPKPASPKKPPPGERRSRSPRKP 2681

Query: 1730 QHGSGSGRSSSRGPYESR--SGHSSVFGQHESGSGHSSAYSQHG 1771
                   RS S  P E R  S   S   Q  S S   S   Q G
Sbjct: 2682 IDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRG 2725



 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 80/342 (23%), Positives = 108/342 (31%), Gaps = 53/342 (15%)

Query: 1668 SRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSS 1727
            SR+  S+  +   +S R+ S   + G    QS     Q       PS     S    + +
Sbjct: 2407 SRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQT 2466

Query: 1728 HGQHGSGSGRSSSRGPYESRSG-HSSVFGQHESGSGHS-------SAYSQHGSGSGHFCS 1779
                GS S  S +     S +G H+ +      G  HS       S  +Q  S       
Sbjct: 2467 TPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQP 2526

Query: 1780 QGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYG------------------- 1820
              +  S+S  SS+     SS+  SSS    GS SS S                       
Sbjct: 2527 AKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAP 2586

Query: 1821 ----QQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHES 1876
                ++G     +P++ +  S S  SSS     S S  SSSS    S S  SS      S
Sbjct: 2587 KEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646

Query: 1877 SSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYG------------ 1924
            SS   +           S      G R  +S R          S SY             
Sbjct: 2647 SSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPS 2706

Query: 1925 ---QHGSGSRQSLGHGQHGSGSG-------QSPSPSRGRHGS 1956
               Q  S S +    GQ G           ++PSP   RH S
Sbjct: 2707 PRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRS 2748



 Score = 46.6 bits (109), Expect = 4e-04
 Identities = 96/384 (25%), Positives = 124/384 (32%), Gaps = 41/384 (10%)

Query: 2372 SRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQS 2431
            SR+  S+  +   +S  + S   + G    QSL          +SP PS     S    +
Sbjct: 2407 SRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLL--PPAQDQPRSPVPSAFSDQSRCLIA 2464

Query: 2432 SSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS 2491
             +    GS S  S +     S +G  +G+    +     S  G+  +S+G      Q  S
Sbjct: 2465 QTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTG-----AQQPS 2519

Query: 2492 TSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSY 2551
                     +  +SS  SSS     S SS SS     GS S  S      GS     P  
Sbjct: 2520 ALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDS-----EGSSLPVQPEV 2574

Query: 2552 G--RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 2609
               R  S +     + + G     +       SSS  SSS S   S S  SS        
Sbjct: 2575 ALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSS------- 2627

Query: 2610 SGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHG 2669
            S  SS      SSS SSS      S S   +  G Q      SP +   G     S    
Sbjct: 2628 SSSSSSSSSSSSSSSSSS------SSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKP 2681

Query: 2670 QHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQ 2729
                   RS S  P E R             S   S   Q  S S     +GQ G +   
Sbjct: 2682 IDSLRDSRSLSYSPVERR-----------RPSPQPSPRDQQSSSSERGSRRGQRGDSRSP 2730

Query: 2730 SSTFDQEGSSTGQSSSYGHRGSGS 2753
            S    +E   T       HR S S
Sbjct: 2731 SHKRRRE---TPSPRPMRHRSSRS 2751



 Score = 46.2 bits (108), Expect = 5e-04
 Identities = 65/234 (27%), Positives = 83/234 (35%), Gaps = 35/234 (14%)

Query: 762  SSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGS-GQASGFGQH 820
            S+G  +  + +   P++ R  SSS  SSS     S +S SSS     S S  + S     
Sbjct: 2512 STGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQ 2571

Query: 821  ESGSGQGYSQHGSASGHFSSQGR-------------HGSTSGQSSSSGQHDSSSGQSSSY 867
               + +       A      +GR               S+S  SSSS    SSS  SSS 
Sbjct: 2572 PEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSS 2631

Query: 868  GQHESASHHASGRGRHGSGSGQSPGHGQRG------SGSGQSPSYGRHGSGSGRSSSSGR 921
                S+S  +S      S S  SP   + G        S + P  G   S S R      
Sbjct: 2632 SSSSSSSSSSS------SSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSL 2685

Query: 922  HGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQ--SSRSEQH 973
              S S   S    +  S Q S   Q  S S       + GSR GQ   SRS  H
Sbjct: 2686 RDSRSLSYSPVERRRPSPQPSPRDQQSSSS-------ERGSRRGQRGDSRSPSH 2732



 Score = 46.2 bits (108), Expect = 5e-04
 Identities = 57/217 (26%), Positives = 71/217 (32%), Gaps = 24/217 (11%)

Query: 1294 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRG--SGSSQSSGYGR 1351
            SS+ S   S S    S     S+S  SS+ D EGSS         +   S +       R
Sbjct: 2532 SSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVR 2591

Query: 1352 HGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS 1411
             G     +P++ +  S S  SSS     S S  SSSS    S S  SS      SSS   
Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651

Query: 1412 SGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYG---------------QH 1456
            +           S      G R  +S R          S SY                Q 
Sbjct: 2652 AKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQ 2711

Query: 1457 GSGSRQSLGHGQHGSGSG-------QSPSPSRGRHGS 1486
             S S +    GQ G           ++PSP   RH S
Sbjct: 2712 SSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRS 2748



 Score = 45.4 bits (106), Expect = 8e-04
 Identities = 68/268 (25%), Positives = 87/268 (32%), Gaps = 39/268 (14%)

Query: 378  GSTSGQASSSGQHGSSSRQSSSYGQHESASRH--SSGRGQHSSGSGQSPGHGQRGSGSGQ 435
            G+ +   SS+G H       +    H        S+G  Q S+ +   P   +R S S  
Sbjct: 2478 GAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSS 2537

Query: 436  SPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHH--------------------ESSSEHS 475
            S SS    +    SSSS    SGS  S   G                      E+  E  
Sbjct: 2538 SSSSSSSSSSSSSSSSSS---SGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGR 2594

Query: 476  SGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGS 535
                        SS      S S  SS      SS+ SSSS     S            S
Sbjct: 2595 PPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-----------SS 2643

Query: 536  GSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES-GSGHSSGLGHQESR--SG 592
             S  SPSP++   ++  + +S   P        S R P +S     S      E R  S 
Sbjct: 2644 SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP 2703

Query: 593  QSSGYGQHGSSSGHSSTHGQHGSTSGQS 620
            Q S   Q  SSS   S  GQ G +   S
Sbjct: 2704 QPSPRDQQSSSSERGSRRGQRGDSRSPS 2731



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 77/299 (25%), Positives = 93/299 (31%), Gaps = 39/299 (13%)

Query: 222  GSGSGQSSGFSQHKSSSGQSSGY-SQHGSGSGHS-------SGYGQHGSRSGQSSRGERH 273
            GS S  S   +   SS+G  +G  S    G  HS       S   Q  S        +  
Sbjct: 2471 GSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKER 2530

Query: 274  RSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSY 333
            RSSS SSSS     S S  S      GS S  S      GS              S    
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDS-----EGSSLPVQPEVALKRVPSPTPA 2585

Query: 334  SRGHYESGSGQ--TSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHG 391
             +     G     T    +  S S  SS  S   S S  SSS     S+S  +SSS    
Sbjct: 2586 PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645

Query: 392  SSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSS 451
            SSS   +  G           +      S + P  G+R S S + P      +   RS S
Sbjct: 2646 SSSPSPAKPGP----------QALPKPASPKKPPPGERRSRSPRKPIDSLRDS---RSLS 2692

Query: 452  SGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSS 510
              P                 S   S   Q  S S   S  GQ G     S +  R+  S
Sbjct: 2693 YSPV-----------ERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPS 2740



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 56/217 (25%), Positives = 72/217 (33%), Gaps = 24/217 (11%)

Query: 2234 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHG--QHGSGSSQSSSYGQ 2291
            SS+ S   S S    S     S+S  SS+ D EGSS          +  S +       +
Sbjct: 2532 SSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVR 2591

Query: 2292 QGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS 2351
            +G     +P++ +  S S  SSS     S S  SSSS    S S  SS      SSS   
Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651

Query: 2352 SGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYG---------------QH 2396
            +           S      G R  +S R          S SY                Q 
Sbjct: 2652 AKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQ 2711

Query: 2397 GSGSRQSLGHGQHGSGSG-------QSPSPSRGRHGS 2426
             S S +    GQ G           ++PSP   RH S
Sbjct: 2712 SSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRS 2748



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 78/330 (23%), Positives = 111/330 (33%), Gaps = 38/330 (11%)

Query: 496  SRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQS 555
            SR+  S+  + + +S  + S   + G    QSL          +SP PS    +S    +
Sbjct: 2407 SRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSL--LPPAQDQPRSPVPSAFSDQSRCLIA 2464

Query: 556  SSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHG---- 611
             +    G  S  S +     S +G  +G+    +     S  G+  +S+G          
Sbjct: 2465 QTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAAL 2524

Query: 612  ----QHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYG----------------- 650
                +  S+S  SSS     ++S  SSS    GS SS S                     
Sbjct: 2525 QPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTP 2584

Query: 651  --QQGSGSGQSP-----SRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGH 703
              ++    G+ P      R R  S    SSS     S S  SSS+    S S  SS    
Sbjct: 2585 APKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644

Query: 704  KSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRS--EQHGSSSGLSSSYGQHGSGSHQ 761
             S S   +           S      G R  +S R   +    S  LS S  +    S Q
Sbjct: 2645 SSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQ 2704

Query: 762  SSGHGRQGSGSGHSPSRVRHGSSSGHSSSH 791
             S   +Q S S     R + G S   S SH
Sbjct: 2705 PSPRDQQSSSSERGSRRGQRGDS--RSPSH 2732



 Score = 42.7 bits (99), Expect = 0.005
 Identities = 73/293 (24%), Positives = 95/293 (32%), Gaps = 25/293 (8%)

Query: 502  SRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPH 561
            S+    G+ A ++SS G H            H S  G+ P+       +G++Q S+    
Sbjct: 2472 SQSLSSGAVATTTSSAGDHNGMLSVPAPGVPH-SDVGEPPA------STGAQQPSALAAL 2524

Query: 562  GYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHG------- 614
                 R SS     S S  SS      S S  SS  G   S S  SS   Q         
Sbjct: 2525 QPAKERRSS----SSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVP 2580

Query: 615  STSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSS 674
            S +       + G     + +  +  S SS SS      S S  S S     S    SSS
Sbjct: 2581 SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2640

Query: 675  YGQHGSGSGWSSSNGPHG---SVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGS 731
                 S S   +  GP       S +    G +                S S    +   
Sbjct: 2641 SSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRR 2700

Query: 732  RSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSS 784
             S Q S  +Q  SSS   S  GQ G     S    R+      SP  +RH SS
Sbjct: 2701 PSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETP----SPRPMRHRSS 2749



 Score = 42.4 bits (98), Expect = 0.007
 Identities = 51/174 (29%), Positives = 69/174 (39%), Gaps = 13/174 (7%)

Query: 2143 SSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSG-SGHSPSRGRHGSGSGHSSSHGQH 2201
            SS G+ +G  S  +        G   +S   +Q S  +   P++ R  S S  SSS    
Sbjct: 2485 SSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS 2544

Query: 2202 GSGSGRSSSR--GPYESRSGHSSVFGQHE-------SGSGHSSAYSQHGSGSGHFCSQGQ 2252
             S S  SSS   G   S S  SS+  Q E       S +       + G       ++ +
Sbjct: 2545 SSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRK 2604

Query: 2253 HGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHG 2306
              S+S  SS+     SS+  SSS     S SS SSS     S S  SPS  + G
Sbjct: 2605 RRSSSSSSSS---SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG 2655



 Score = 41.6 bits (96), Expect = 0.011
 Identities = 74/284 (26%), Positives = 104/284 (36%), Gaps = 25/284 (8%)

Query: 151  GTESISR-RLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQ---SSGRGQCGSGSGQSPNYG 206
            G++S+S   ++     +G HN      +  G  +SD  +   S+G  Q  + +   P   
Sbjct: 2471 GSQSLSSGAVATTTSSAGDHNGMLSVPAP-GVPHSDVGEPPASTGAQQPSALAALQPAKE 2529

Query: 207  QHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYS----------QHGSGSGHSSG 256
            +  S S  SSS+ +  S S  SS  S   SSS  S G S          +  S +     
Sbjct: 2530 RRSSSSSSSSSSSSSSSSSSSSSS-SSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKE 2588

Query: 257  YGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGS 316
              + G     +    + RSSS SSSS     S S  S       S S  S S     S S
Sbjct: 2589 AVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648

Query: 317  GHSSSHGQHGSGSSYSYSR---GHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSS 373
               +  G        S  +   G   S S +       +S S   S   +    S   S 
Sbjct: 2649 PSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERR-RPSPQPSP 2707

Query: 374  QGQHGSTSGQASSSGQHGSSSRQSSSYGQHESAS----RHSSGR 413
            + Q  S+S + S  GQ G  SR  S   + E+ S    RH S R
Sbjct: 2708 RDQQSSSSERGSRRGQRG-DSRSPSHKRRRETPSPRPMRHRSSR 2750



 Score = 39.7 bits (91), Expect = 0.043
 Identities = 60/214 (28%), Positives = 74/214 (34%), Gaps = 27/214 (12%)

Query: 147  SLKPGTES-ISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQC---------- 195
            +L+P  E   S   S     S   +S S  SSS G  +SDS  SS   Q           
Sbjct: 2523 ALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSP 2582

Query: 196  ----------GSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYS 245
                      G     +P   +  S S  SSS+ +  S S  SS  S   SSS  SS  S
Sbjct: 2583 TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642

Query: 246  QHGSGSGHSSGYGQHGSRSGQSSR----GERHRSSSGSSSSYGQHGSGSRQSLGHGRQGS 301
               S S   +  G        S +    GER RS S          S S       R+  
Sbjct: 2643 SSSSSSPSPAKPGPQALPKPASPKKPPPGER-RSRSPRKPIDSLRDSRSLSYSPVERRRP 2701

Query: 302  GSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSR 335
              + SP   +  S S   S  GQ G   S S+ R
Sbjct: 2702 SPQPSPRD-QQSSSSERGSRRGQRGDSRSPSHKR 2734



 Score = 35.8 bits (81), Expect = 0.62
 Identities = 124/495 (25%), Positives = 168/495 (33%), Gaps = 60/495 (12%)

Query: 150  PGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGR-GQCGSGSGQSPNYGQH 208
            P   ++ RR        G+  S  G SS+   ++S  H    R  + GS S   P     
Sbjct: 1627 PAPRALPRRSRSGSSSKGRGPSPEGSSST---ESSPEHPPKSRTARRGSRSSPEPKTKSR 1683

Query: 209  GSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYS--QHGSGSGHSSGYGQHGSRSGQ 266
                 +SS +    +   + S  S+  SSS ++   +  +H      SS      SRS +
Sbjct: 1684 TPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSR 1743

Query: 267  -----SSRGERHRSSSGSSSSYGQHG---------------------SGSRQSLGHGRQG 300
                 SS   +  S  G S S    G                     SGS QS    RQ 
Sbjct: 1744 RRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQR 1803

Query: 301  SGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSG 360
            S SR   +  R G    HS S  +  S  + S  R     G  +T    +  S S  S  
Sbjct: 1804 SRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRR----RGRSRTPPTSRKRSRSRTSPA 1859

Query: 361  YSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGS 420
              K    S   +S   H  +  +     +  S SR +S   +  S SR S  R    S S
Sbjct: 1860 PWKR---SRSRASPATHRRSRSRTPLISRRRSRSR-TSPVSRRRSRSRTSVTR--RRSRS 1913

Query: 421  GQSPGHGQRGSGSGQSP-----SSGQHGTGFGRSSSSGPYVSGSGYSSGFG--HHESSSE 473
              SP   +R S S   P     S  +  T   RS S  P V+     S         S  
Sbjct: 1914 RASP-VSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRS 1972

Query: 474  HSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRH 533
             +S  T+  S S  +S   +  SRS  S    R+  S   +S   +  S SR      R 
Sbjct: 1973 RTSPITRRRSRS-RTSPVTRRRSRSRTSPVTRRR--SRSRTSPVTRRRSRSRTPPAIRRR 2029

Query: 534  GSGSGQSPSPSRGRHESGS-----RQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQE 588
                 ++P   R R  S S     R+S S  P      RS +R P       +SG     
Sbjct: 2030 --SRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDR 2087

Query: 589  SRSGQSSGYGQHGSS 603
            SRS        H  S
Sbjct: 2088 SRSATPPATRNHSGS 2102



 Score = 32.7 bits (73), Expect = 5.3
 Identities = 34/133 (25%), Positives = 41/133 (30%), Gaps = 25/133 (18%)

Query: 2727 SGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYG-------------------------R 2761
            S  SS+     SS+  SSS     SGSS S   G                         R
Sbjct: 2532 SSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVR 2591

Query: 2762 HGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDG 2821
             G     + +  +  S S  SSS     S S  SS  S   S S     S     S+   
Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651

Query: 2822 GSSGSYFLSFPSS 2834
               G   L  P+S
Sbjct: 2652 AKPGPQALPKPAS 2664



 Score = 32.3 bits (72), Expect = 6.9
 Identities = 42/160 (26%), Positives = 51/160 (31%), Gaps = 27/160 (16%)

Query: 144  VRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSP 203
            VR    P      R+       S   +S S  SSS    +S S  SS      S S  SP
Sbjct: 2590 VREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP 2649

Query: 204  NYGQHG--------------SGSGQSSSN----DTHGSGSGQSSGFSQHKSSSGQSSGYS 245
            +  + G               G  +S S     D+       S    + +  S Q S   
Sbjct: 2650 SPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRD 2709

Query: 246  QHGSGSGHSSGYGQHGS---------RSGQSSRGERHRSS 276
            Q  S S   S  GQ G          R   S R  RHRSS
Sbjct: 2710 QQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSS 2749


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score =  126 bits (317), Expect = 3e-28
 Identities = 362/1590 (22%), Positives = 566/1590 (35%), Gaps = 173/1590 (10%)

Query: 365  GSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSP 424
            G G     S G   S   +A+ + +       SS      +A++H      HS+ SG S 
Sbjct: 25   GDGRAEGFSLGLPLSEQARAAGAREKERQEVSSSPDVSELTATKHEETVINHSTFSGFSQ 84

Query: 425  GHGQR-------GSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSG 477
              G          + S  +PSS    T F     S  +++GS  +  F    ++S HS  
Sbjct: 85   ITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEE 144

Query: 478  YTQHGSGSGHSSGHGQHGSRSGQS-SRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSG 536
             T   SG G ++G     S S  S   GE + S   S+S       GS  + G S   + 
Sbjct: 145  STVSHSGPG-ATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTT 203

Query: 537  SGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSG 596
               SP  S  R  S +R +SS      G    S+      G  H+       +  G S  
Sbjct: 204  FYSSPR-SPDRTLSPARTTSS------GVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQE 256

Query: 597  YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGS 656
                 S  G + T    G+T+   SS G    T   S  + +       ++  G   + +
Sbjct: 257  STASHSIPGSTDTTLSPGTTT--PSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEAST 314

Query: 657  GQSPSRGRHGSDFGHSSSYGQHGSGS---GWSSSNGPHGSVSGQSSGFGHKS---GSGQS 710
                S G   +    +SS    G  +    W SS     + SG +S F   S    S  S
Sbjct: 315  PVHSSTGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPS 374

Query: 711  SGYSQHGSGSSHSSGYRKHGS-------RSGQSSRSEQHGSSSGLSSSYGQHGS-GSHQS 762
            S  + H S SS + G+ +  +        +  +    +  +S  +  S   H S GS Q+
Sbjct: 375  STPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQT 434

Query: 763  SGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGH--YESGSGQASGFGQH 820
                   + SGHS        S+ H+ S     S  S +++  H  Y S  G        
Sbjct: 435  MHFPESSTTSGHSEESATFHGSTTHTKS-----STPSTTAALAHTSYHSSLGSTETTHFR 489

Query: 821  ESGSGQGYSQHGSASGHFSSQGRHGST---SGQSSSSGQHDSSSGQSSSYGQHESASHHA 877
            +S +  G S+   AS   SS     +T   +G + S    DS+    SS     +A    
Sbjct: 490  DSSTISGRSEESKAS--HSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTAL--- 544

Query: 878  SGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSS 937
                    GS   PG  ++ +    SP            S    H   S  SSG   +S+
Sbjct: 545  -------PGSTTKPGLSEKSTTFYSSP-----------RSPDTTHLPASMTSSGVSEEST 586

Query: 938  SGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLG-- 995
            +  S        GS H++++    +  G S  S    SS G + +    GS +  SLG  
Sbjct: 587  TSHSR------PGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPE 640

Query: 996  HGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRES 1055
            +    S  G + +     + + SG   +  P       SS+R P+ + S   S      +
Sbjct: 641  YTTFHSRPGSTETTLLPDNTTASGLLEASMPVH-----SSTRSPHTTLSPAGS-----TT 690

Query: 1056 RSGQSSGYGQHGSSSGHSSTHGQHGSTSG-QSSSCGQHGASSGQSSSHGQHGSGSSQSSG 1114
            R G+S+ +  H   S + +      +TS     S   HG+ S   ++   H S  S +SG
Sbjct: 691  RQGESTTF--HSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTT---HISARSTTSG 745

Query: 1115 YGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH--GSGLGESSGFGHHES 1172
               + +    SPG  Q         + GR G  S  S SS  H   S    +S      +
Sbjct: 746  LVEESTTYHSSPGSTQTMHFPESDTTSGR-GEESTTSHSSTTHTISSAPSTTSALVEEPT 804

Query: 1173 S--SGQSSSYSQHGSGSGHSSGYGQH--GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQ 1228
            S  S   S+ + H   S  +SG  +    S S Q + G     +  ++S      + S  
Sbjct: 805  SYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPI 864

Query: 1229 SSGHGRQGSGSGHSPSRG-RHGSGLGHSS--SHGQHGSGSGRSSSRGPYESRSGHSSVFG 1285
            SSG     +  G + + G    S   HSS  S     S +  +SS    ES + HS    
Sbjct: 865  SSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHS---- 920

Query: 1286 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQS-STFDQEGSSTGQSSSYGHRGSGSS 1344
                GS H++A+    +  G      +H +TS  S  + D        ++      + S 
Sbjct: 921  --RPGSTHTTAFPDSTTTPG----LSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSP 974

Query: 1345 QSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 1404
             SSG     A  G + +    G     ++ Y    S     S +    SG  + S   H 
Sbjct: 975  ISSGSTETTALPGSTTTA---GLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS 1031

Query: 1405 ESSSWQSS----GCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGS 1460
               S  ++      T  G     ++S+   GS     S      SS G  S+    G GS
Sbjct: 1032 RPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGS 1091

Query: 1461 RQS--LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGS---------GWSSSRGP 1509
             ++  L      SG  ++ +P    H S     ++ SP GS +          W SS+  
Sbjct: 1092 TETTLLPDNTTASGLLEASTPV---HSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDT 1148

Query: 1510 YESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQS 1569
              +  + +S      + S        HGS S   +TH    ST+         G S   +
Sbjct: 1149 MPAPPTTTSAFVELSTTS--------HGSPSSIPTTHFSASSTT--------FGRSEEST 1192

Query: 1570 SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGS 1629
            + H    + ++  S      SG  +         GS Q+  +    + SGRS  S    S
Sbjct: 1193 TVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHS 1252

Query: 1630 GLGESSGFGHHESSSGQSSSYSQHGS-GSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSR 1688
                +       +S+      S H S GS  ++ + +  + SG+S       ++S SS  
Sbjct: 1253 STTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRS----EESTASHSSPD 1308

Query: 1689 YGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSG--RSSSRGPYES 1746
                       +  GR    +    S G   + L  +++     + S    SSSR P ++
Sbjct: 1309 TNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQT 1368

Query: 1747 RS----GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQ 1802
             S      SS+ G  E  S +S A S H +    F +       S +S+TF  +  ST  
Sbjct: 1369 LSPASMTSSSISG--EPTSLYSQAESTHTTA---FPASTTTSGLSQESTTFHSKPGSTET 1423

Query: 1803 SSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHG 1862
            + S      GS  +SS+ Q+ +     P     GS     S       G    S++    
Sbjct: 1424 TLS-----PGSITTSSFAQEFTTPHSQP-----GSALSTVSPASTTVPGLSEESTTFYSS 1473

Query: 1863 SGSGQSSGFGHHESSSWQSSGYTQHGSGSG 1892
             GS +++ F H  + S  S   T      G
Sbjct: 1474 PGSTETTAFSHSNTMSIHSQQSTPFPDSPG 1503



 Score =  115 bits (288), Expect = 6e-25
 Identities = 339/1546 (21%), Positives = 554/1546 (35%), Gaps = 208/1546 (13%)

Query: 671  HSSSYGQHGSGSGWSSSNGP--HGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRK 728
            H  +   H + SG+S   G   + S+ G ++     S S   + +S +G   +  +G   
Sbjct: 69   HEETVINHSTFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITG--- 125

Query: 729  HGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHS 788
                    S + +H   S  +S + +  + SH   G     +G+   PS         HS
Sbjct: 126  --------STATKHFLDSSTNSGHSEESTVSHSGPG----ATGTTLFPS---------HS 164

Query: 789  SSHGQHGSGTSCSSSCGHYES----GSGQASGFGQHES---GSGQGYSQHGSASGHFSSQ 841
            ++    G   +   +    E+    GS   +G  +  +    S +   +  S +   SS 
Sbjct: 165  ATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSG 224

Query: 842  GRHGSTSGQSSSSGQHDSSSGQSSSY---GQHESASHHASGRGRHGSGSGQSPGH----- 893
                ST+  S     H  +   S++     Q  +ASH   G     + +  SPG      
Sbjct: 225  VSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPG----STDTTLSPGTTTPSS 280

Query: 894  -GQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSG-- 950
             G   +    SP Y +       +++SG   + +   S  G   ++   +  T H     
Sbjct: 281  LGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPASSTTHEGEPT 340

Query: 951  --SGHSSSYEQHGSRSGQSSRSEQHGSS--SGSSSSYGQHGSGSRQSLGHGQHGSGSGQS 1006
                  SS +   + SG +S   +  ++  S  SS+   H S S  +LGH +        
Sbjct: 341  TFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEE------- 393

Query: 1007 PSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQH 1066
               S   H S    +++  P RS +          SG    S   HR   S Q+  + + 
Sbjct: 394  ---STPVHSSPVATATTPPPARSAT----------SGHVEESTAYHRSPGSTQTMHFPES 440

Query: 1067 GSSSGHSSTHGQ-HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQS 1125
             ++SGHS      HGST+   SS     A+   +S H     GS++++ +    + SG+S
Sbjct: 441  STTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSS--LGSTETTHFRDSSTISGRS 498

Query: 1126 PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGS 1185
                +    S  SP           S+ S   G         G  E+++   S+      
Sbjct: 499  ----EESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKP--- 551

Query: 1186 GSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSR 1245
            G    S       RS  ++      +SSG S       S SR  S H     GS   P  
Sbjct: 552  GLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEE--STTSHSRPGSTHTTAFPGSTTMPGL 609

Query: 1246 GRHGSGLGHSS---SHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGS 1302
             +  +   HSS   +      GS  +SS GP E  + HS        GS  ++    + +
Sbjct: 610  SQESTA-SHSSPGPTDTTLSPGSTTASSLGP-EYTTFHS------RPGSTETTLLPDNTT 661

Query: 1303 GSGHF-CSQGQHGSTSGQSSTFDQEGSST--GQSSSYGHRGSGSSQSSGYGRHGAGSGQS 1359
             SG    S   H ST    +T    GS+T  G+S+++ H    S+ +         +   
Sbjct: 662  ASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTF-HSWPSSNDTRPAPPTTTSAFVE 720

Query: 1360 PSRGRHGSGSG--------HSSSYGQHGSGSGWSSSSGR----HGSGSGQSSGFGHHESS 1407
            PS   HGS S          S++ G     + + SS G     H   S  +SG G   ++
Sbjct: 721  PSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTT 780

Query: 1408 SWQSSGCTQHGSGSGHSSSYEQHGS-RSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGH 1466
            S  S+  T   + S  S+  E+  S  S   S    H   S ++S   +    S  S   
Sbjct: 781  SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQ-- 838

Query: 1467 GQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESR 1526
                  +G    P+R  +    G+S++ SP  SGS  +++      GS+ + GL  R   
Sbjct: 839  ----DATGTIVLPARSTNSVLLGESTT-SPISSGSMETTAL----PGSTTTPGLSER--- 886

Query: 1527 SGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGS-------GS 1579
                       S++ HSS      +T+   +S    G S   ++SH + GS        S
Sbjct: 887  -----------STTFHSSPRSP--ATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDS 933

Query: 1580 SQSSGYGRQGSGSGQSPGHGQRG--SGSRQSPSYGRHGSG---SGRSSSSGQHGS----G 1630
            + + G  R  + S  SPG         S  +   G   +    SG + ++   GS    G
Sbjct: 934  TTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAG 993

Query: 1631 LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYG 1690
            L E S   +    S  ++      + SG S       SR G +      GS++       
Sbjct: 994  LSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP----- 1048

Query: 1691 QHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGH 1750
              G     ++ H   GS       R    S LG  S+    G GS  ++      + SG 
Sbjct: 1049 --GVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGL 1106

Query: 1751 SSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQS-----STFDQEGSSTG---- 1801
                    S   HSS  S   + S    +  Q  ST+ QS      T     ++T     
Sbjct: 1107 LEA-----STPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVE 1161

Query: 1802 -QSSSHGQ-------HGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSG 1853
              ++SHG        H S SS +    ++ +    SP           S++ G     + 
Sbjct: 1162 LSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTA 1221

Query: 1854 WSSSSGR----HGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGS-RSGQSS 1908
            + SS G     H   S  +SG      +S  S+ +T     S  S+  E+  S  S   S
Sbjct: 1222 YHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGS 1281

Query: 1909 RGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYG 1968
                H   S ++S   +  + S  S         +G +P P+         +S+++    
Sbjct: 1282 IATTHFPESSTTSGRSEESTASHSS------PDTNGITPLPAHFTTSGRIAESTTFYISP 1335

Query: 1969 SGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSS 2028
                 + +      G    S + +  SRS   +      +S   SS  G+  S   Q+ S
Sbjct: 1336 GSMETTLASTATTPGLSAKSTILYSSSRSPDQT---LSPASMTSSSISGEPTSLYSQAES 1392

Query: 2029 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ---SPGHGQRGSGSRQ-SPSYGRH 2084
               H  +   S++     SG SQ S       GS +   SPG     S +++ +  + + 
Sbjct: 1393 T--HTTAFPASTTT----SGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQP 1446

Query: 2085 GSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 2130
            GS     S +    PGL E S   +    S +++++S   + S HS
Sbjct: 1447 GSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHS 1492



 Score =  114 bits (286), Expect = 1e-24
 Identities = 358/1610 (22%), Positives = 584/1610 (36%), Gaps = 198/1610 (12%)

Query: 551  GSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTH 610
            G  + +S G  G G     S G   S    ++G   +E +   SS      +++ H  T 
Sbjct: 14   GLVEFASPGDDGDGRAEGFSLGLPLSEQARAAGAREKERQEVSSSPDVSELTATKHEETV 73

Query: 611  GQHGSTSGQSSSCGQHGATS-GQSSSHGQHGSGSSQSSRYGQQG------SGSGQSPSRG 663
              H + SG S   G    TS G +++     S S   + +   G      +GS  +    
Sbjct: 74   INHSTFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFL 133

Query: 664  RHGSDFGHSSSYGQHGSGSGWSSSN-GPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSH 722
               ++ GHS       SG G + +   P  S +    G    S    +S  +    GS+ 
Sbjct: 134  DSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTT 193

Query: 723  SSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGS--GHSPSRVR 780
            ++G  +  +    S RS     S   ++S    G     ++ H R G         S   
Sbjct: 194  TAGLSEKSTTFYSSPRSPDRTLSPARTTS---SGVSEKSTTSHSRPGPTHTIAFPDSTTM 250

Query: 781  HGSSSGHSSSHGQHGS-------GTSCSSSCG------HYESGSGQASGFGQHESGSG-- 825
             G S   ++SH   GS       GT+  SS G      H   G  + +    + + SG  
Sbjct: 251  PGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLL 310

Query: 826  --------QGYSQHGSASGHFSSQGRHGSTSGQS--SSSGQHDSSSGQSSSYGQHESASH 875
                       S H + S   S+      T+ QS  SS     + SG +S++ +  +  H
Sbjct: 311  EASTPVHSSTGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYH 370

Query: 876  HA--SGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFG 933
             +  S    H S S  + GH +  +    SP          RS++SG       +S+ + 
Sbjct: 371  SSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGH----VEESTAYH 426

Query: 934  HKSSSGQSSGYTQHGSGSGHSS-SYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGS-GSR 991
                S Q+  + +  + SGHS  S   HGS +   S +    S++ + +    H S GS 
Sbjct: 427  RSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTP---STTAALAHTSYHSSLGST 483

Query: 992  QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSG---WSSSRGPYESGSGHSS 1048
            ++       + SG+S   S+  H S    +++  P  S        S+  P  SGS  ++
Sbjct: 484  ETTHFRDSSTISGRSEE-SKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETT 542

Query: 1049 GLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSG 1108
             L    ++ G S       S++ +SS       T+   +S    G S   ++SH + GS 
Sbjct: 543  ALPGSTTKPGLSEK-----STTFYSSPRSP--DTTHLPASMTSSGVSEESTTSHSRPGST 595

Query: 1109 SSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFG 1168
             + +        GS   PG  Q  + S  SP     G      S      S LG      
Sbjct: 596  HTTAF------PGSTTMPGLSQESTASHSSP-----GPTDTTLSPGSTTASSLGPEYTTF 644

Query: 1169 HHESSSGQSSSYSQHGSGSG--------HSSGYGQHGSRSGQSSRGERHGSSSGSSSHYG 1220
            H    S +++    + + SG        HSS    H + S   S   R G S+  + H  
Sbjct: 645  HSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGST-TRQGEST--TFHSW 701

Query: 1221 QHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYE-SRSG 1279
               + +R +       + +   PS   HGS     ++H      S RS++ G  E S + 
Sbjct: 702  PSSNDTRPAPP---TTTSAFVEPSTTSHGSPSSIPTTHI-----SARSTTSGLVEESTTY 753

Query: 1280 HSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHR 1339
            HSS           S   S  G  S    S   H  +S  S+T     +   + +SY H 
Sbjct: 754  HSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTT----SALVEEPTSY-HS 808

Query: 1340 GSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGS----GWSSSSGRHGSGS 1395
              GS+ ++ +      SG+S       S + HSS   Q  +G+      S++S   G  +
Sbjct: 809  SPGSTATTHFPDSSTTSGRSEE-----SIASHSS---QDATGTIVLPARSTNSVLLGEST 860

Query: 1396 GQSSGFGHHESSSWQSSGCT---QHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSS 1452
                  G  E+++   S  T      S + HSS      + S  S+     G S  S++S
Sbjct: 861  TSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSS--GVSEESTTS 918

Query: 1453 YGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGW--SSSRGPY 1510
            + + GS    +        G  +  + S   H S     ++  P  + +      +  P 
Sbjct: 919  HSRPGSTHTTAFPDSTTTPGLSRHSTTS---HSSPGSTDTTLLPASTTTXLVGEPTTSPI 975

Query: 1511 ESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSS 1570
             SGS+ ++ L    + +G S       S++ +SS      + S  S++    G S   ++
Sbjct: 976  SSGSTETTALPGSTTTAGLS-----EKSTTFYSSPRSPDTTLSPASTT--SSGVSEESTT 1028

Query: 1571 SHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSG 1630
            SH + GS  + +        GS   PG  Q  + S  SP     GS     S      S 
Sbjct: 1029 SHSRPGSTHTTAF------PGSTTMPGVSQESTASHSSP-----GSTDTTLSPRSTTASS 1077

Query: 1631 LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYG 1690
            LG  S   H    S +++    + + SG         S    SS G    + S + S   
Sbjct: 1078 LGPESTTFHSGPGSTETTLLPDNTTASGL-----LEASTPVHSSTGSPRTTLSPAGSTTR 1132

Query: 1691 QHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGH 1750
            Q  S + QS    +    +  +P           ++SHG        S S  P    S  
Sbjct: 1133 QGESTTFQSWPSSKD---TMPAPPTTTSAFVELSTTSHG--------SPSSIPTTHFSAS 1181

Query: 1751 SSVFGQ-HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQH 1809
            S+ FG+  ES + HSS  +   + S              +S+T      ST   SS    
Sbjct: 1182 STTFGRSEESTTVHSSPVAPATTPS------------PARSTTSGLVEESTAYHSS---- 1225

Query: 1810 GSGSSQSSSYGQQGSGSGQS-PSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQS 1868
              GS+Q+  + +  + SG+S  SR  H S +   SS     S      +S     GS  +
Sbjct: 1226 -PGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIAT 1284

Query: 1869 SGFGHHESSSWQSSGYT-QHGSGSGHS-SSYEQHGSRSGQSSRGEQHGSSSGS-----SS 1921
            + F    ++S +S   T  H S   +  +    H + SG+ +       S GS     +S
Sbjct: 1285 THFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLAS 1344

Query: 1922 SYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYE 1981
            +    G  ++ ++ +    S   Q+ SP+     S SG+ +S   Y       ++  P  
Sbjct: 1345 TATTPGLSAKSTILYSSSRS-PDQTLSPASMTSSSISGEPTSL--YSQAESTHTTAFP-- 1399

Query: 1982 SGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST----------HGQHGSASGQSSSCGQ 2031
              S  +SGL    +      G  +   S G  +T          H Q GSA    S    
Sbjct: 1400 -ASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPAST 1458

Query: 2032 HGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSY 2081
                  + S+      GS++++ +    S S     H Q+ +    SP +
Sbjct: 1459 TVPGLSEESTTFYSSPGSTETTAF----SHSNTMSIHSQQSTPFPDSPGF 1504



 Score =  104 bits (260), Expect = 1e-21
 Identities = 285/1290 (22%), Positives = 452/1290 (35%), Gaps = 181/1290 (14%)

Query: 216  SSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRS 275
            +S   H S     +  S   S++ +    +     S   +     G+ S        + S
Sbjct: 312  ASTPVHSSTGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHS 371

Query: 276  SSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSR 335
            S  S+ +   H S S  +LGH  + +    SP           S++ G     ++Y    
Sbjct: 372  SPSSTPT--THFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAY---- 425

Query: 336  GHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSR 395
             H   GS QT  F +  + SG S       S + H S+     ST    ++       S 
Sbjct: 426  -HRSPGSTQTMHFPESSTTSGHS-----EESATFHGSTTHTKSSTPSTTAALAHTSYHSS 479

Query: 396  QSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPY 455
              S+   H   S   SGR + S  S  SP        +   P+        G S+ S P 
Sbjct: 480  LGSTETTHFRDSSTISGRSEESKASHSSPD----AMATTVLPAGSTPSVLVGDSTPS-PI 534

Query: 456  VSGS-------GYSSGFGHHESS----SEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRG 504
             SGS       G ++  G  E S    S   S  T H   S  SSG  +  + S      
Sbjct: 535  SSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTS-----H 589

Query: 505  ERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYG 564
             R GS+  ++        GS    G S+  + S  SP P+      GS  +SS GP  Y 
Sbjct: 590  SRPGSTHTTAF------PGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPE-YT 642

Query: 565  SGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG 624
            +  S        GS  ++ L    + SG         S   HSST   H + S   S+  
Sbjct: 643  TFHS------RPGSTETTLLPDNTTASGL-----LEASMPVHSSTRSPHTTLSPAGSTTR 691

Query: 625  QHGATSGQS--SSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGS 682
            Q  +T+  S  SS+    +  + +S + +  + S  SPS          S++ G     +
Sbjct: 692  QGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEEST 751

Query: 683  GWSSSNGP----HGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGS--RSGQS 736
             + SS G     H   S  +SG G +S +  SS      S  S +S   +  +   S   
Sbjct: 752  TYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPG 811

Query: 737  SRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGS 796
            S +  H   S  +S   +    SH S    +  +G+   P+R         S++    G 
Sbjct: 812  STATTHFPDSSTTSGRSEESIASHSS----QDATGTIVLPAR---------STNSVLLGE 858

Query: 797  GTSCSSSCGHYES----GSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSS 852
             T+   S G  E+    GS    G  +  +      + H S      S     S +  +S
Sbjct: 859  STTSPISSGSMETTALPGSTTTPGLSERST------TFHSSP----RSPATTLSPASTTS 908

Query: 853  SSGQHDSSSGQSSSYGQHESA---SHHASGRGRHGSGSGQSPGHGQR------------- 896
            S    +S++  S     H +A   S    G  RH + S  SPG                 
Sbjct: 909  SGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVG 968

Query: 897  -------GSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGS 949
                    SGS ++ +     + +G S  S    S S +S       +S  SSG ++  +
Sbjct: 969  EPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYS-SPRSPDTTLSPASTTSSGVSEEST 1027

Query: 950  ------GSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1003
                  GS H++++    +  G S  S    SS GS+ +     S +  SLG        
Sbjct: 1028 TSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLG-------- 1079

Query: 1004 GQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGH---SSGLGHRESRSGQS 1060
               P  +    G GS +++      + SG   +  P  S +G    +       +R G+S
Sbjct: 1080 ---PESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGES 1136

Query: 1061 SGYGQHGSSSG---------------HSSTHGQHGS--TSGQSSSCGQHGASSGQSSSHG 1103
            + +    SS                  +++HG   S  T+  S+S    G S   ++ H 
Sbjct: 1137 TTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHS 1196

Query: 1104 QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGE 1163
               + ++  S      SG  +         GS Q+  +    + SGRS  S    S    
Sbjct: 1197 SPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTH 1256

Query: 1164 SSGFGHHESSSGQSSSYSQHGS-GSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQH 1222
            +       +S+      S H S GS  ++ + +  + SG+        S   ++SH    
Sbjct: 1257 TISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGR--------SEESTASHSSPD 1308

Query: 1223 GSGSRQSSGH----GRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSG--RSSSRGPYES 1276
             +G      H    GR    +    S G   + L  +++     + S    SSSR P ++
Sbjct: 1309 TNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQT 1368

Query: 1277 RS----GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQ 1332
             S      SS+ G  E  S +S A S H +    F +       S +S+TF  +  ST  
Sbjct: 1369 LSPASMTSSSISG--EPTSLYSQAESTHTTA---FPASTTTSGLSQESTTFHSKPGSTET 1423

Query: 1333 SSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHG 1392
            + S      GS  +S + +        P     GS     S       G    S++    
Sbjct: 1424 TLS-----PGSITTSSFAQEFTTPHSQP-----GSALSTVSPASTTVPGLSEESTTFYSS 1473

Query: 1393 SGSGQSSGFGHHESSSWQSSGCTQHGSGSG 1422
             GS +++ F H  + S  S   T      G
Sbjct: 1474 PGSTETTAFSHSNTMSIHSQQSTPFPDSPG 1503



 Score = 97.8 bits (242), Expect = 1e-19
 Identities = 305/1357 (22%), Positives = 491/1357 (36%), Gaps = 169/1357 (12%)

Query: 1498 GSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSS 1557
            G G     S G   S  + ++G   +E +   SS      +++ H  T   H + SG S 
Sbjct: 25   GDGRAEGFSLGLPLSEQARAAGAREKERQEVSSSPDVSELTATKHEETVINHSTFSGFSQ 84

Query: 1558 SCGQH-GASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS 1616
              G     S G +++     S S   + +   G             +GS  +  +    +
Sbjct: 85   ITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFI-------TGSTATKHFLDSST 137

Query: 1617 GSGRSSSSGQHGSGLGESSG--FGHHESSS---GQSSSYSQHGSGSGHSSGYGQHGSRSG 1671
             SG S  S    SG G +    F  H ++S   G+  + S   S S  ++      + +G
Sbjct: 138  NSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKT-SPITSASMETTALPGSTTTAG 196

Query: 1672 QSSRGERHGSSSRSS------SRYGQHGSGSRQSSGHGRQGSGSGQS--PSRGRHGSGLG 1723
             S +     SS RS       +R    G   + ++ H R G     +   S    G    
Sbjct: 197  LSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQE 256

Query: 1724 HSSSHGQHGS-------GSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSG- 1775
             ++SH   GS       G+   SS GP ES + HSS       G   ++    + + SG 
Sbjct: 257  STASHSIPGSTDTTLSPGTTTPSSLGP-ESTTFHSS------PGYTKTTRLPDNTTTSGL 309

Query: 1776 -------HFCSQGQHGSTSGQSSTFDQEGSSTGQS--SSHGQHGSGSSQSSSYGQQGSGS 1826
                   H  +   H + S  SST  +   +T QS  SS     + S  +S++ +  +  
Sbjct: 310  LEASTPVHSSTGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTY 369

Query: 1827 GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSS----------SGRHGSGSGQSSGFGHHES 1876
              SPS       S  S++ G     +   SS          +    SG  + S   H   
Sbjct: 370  HSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSP 429

Query: 1877 SSWQSSGYTQHGSGSGHSS-SYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGS-GSRQSL 1934
             S Q+  + +  + SGHS  S   HGS +   S      S++ + +    H S GS ++ 
Sbjct: 430  GSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTP---STTAALAHTSYHSSLGSTETT 486

Query: 1935 GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSG---WSSSRGPYESGSGHSSGLG 1991
                  + SG+S   S+  H S    +++  P GS        S+  P  SGS  ++ L 
Sbjct: 487  HFRDSSTISGRSEE-SKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALP 545

Query: 1992 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQ 2051
               ++ G S       SS     T   H  AS  SS     G S   ++SH + GS  + 
Sbjct: 546  GSTTKPGLSEKSTTFYSSPRSPDT--THLPASMTSS-----GVSEESTTSHSRPGSTHTT 598

Query: 2052 SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHE 2111
            +        GS   PG  Q  + S  SP         G +++S      LG      H  
Sbjct: 599  AF------PGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASS-----LGPEYTTFHSR 647

Query: 2112 SSSGQSSSYSQHGSGSG--------HSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHG 2163
              S +++    + + SG        HSS    H + S            +GS++R G+  
Sbjct: 648  PGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLS-----------PAGSTTRQGEST 696

Query: 2164 S-GSRQSSGHGRQGSGSGHS----PSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYE-SR 2217
            +  S  SS   R    +  S    PS   HGS S   ++H      S RS++ G  E S 
Sbjct: 697  TFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHI-----SARSTTSGLVEEST 751

Query: 2218 SGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHG 2277
            + HSS           S   S  G  S    S   H  +S  S+T       T   SS  
Sbjct: 752  TYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSS-- 809

Query: 2278 QHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGS----GWSSSSGRHGS 2333
                GS+ ++ +    + SG+S       S + HSS   Q  +G+      S++S   G 
Sbjct: 810  ---PGSTATTHFPDSSTTSGRSEE-----SIASHSS---QDATGTIVLPARSTNSVLLGE 858

Query: 2334 GSGQSSGFGHHESSSWQSSGYT---QHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSS 2390
             +      G  E+++   S  T      S + HSS      + S  S+     G S  S+
Sbjct: 859  STTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSS--GVSEEST 916

Query: 2391 SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGW--SSSRG 2448
            +S+ + GS    +        G  +  + S   H S     ++  P  + +      +  
Sbjct: 917  TSHSRPGSTHTTAFPDSTTTPGLSRHSTTS---HSSPGSTDTTLLPASTTTXLVGEPTTS 973

Query: 2449 PYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQ 2508
            P  SGS  ++ L    + +G S       SS     T     ST+    S     + S  
Sbjct: 974  PISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRP 1033

Query: 2509 SSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHG 2568
             S+H     GS+   G  ++ + S  SPG        R + +     S  G  S++   G
Sbjct: 1034 GSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTA-----SSLGPESTTFHSG 1088

Query: 2569 SGLGESSGFGHHESSSG-QSSSYSQHGSGSGHSSGYGQHGS--RSGQSSRGERHGSSSG- 2624
             G  E++    + ++SG   +S   H S     +     GS  R G+S+  +   SS   
Sbjct: 1089 PGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDT 1148

Query: 2625 ------SSSHYGQ-----HGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGS 2673
                  ++S + +     HGS S   + H    S S  +  R    + +  S        
Sbjct: 1149 MPAPPTTTSAFVELSTTSHGSPSSIPTTH---FSASSTTFGRSEESTTVHSSPVAPATTP 1205

Query: 2674 GSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHF-CSQGQHGSTSGQSST 2732
               RS++ G  E    + S       GS  +  + +  + SG    S+  H ST+   S+
Sbjct: 1206 SPARSTTSGLVEESTAYHS-----SPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISS 1260

Query: 2733 FDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQS 2769
                 S+  +  +  H   GS  ++ +      SG+S
Sbjct: 1261 PPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRS 1297



 Score = 61.6 bits (148), Expect = 1e-08
 Identities = 182/818 (22%), Positives = 295/818 (36%), Gaps = 99/818 (12%)

Query: 203  PNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQ--HGSGSGHSSGYGQH 260
            P+   HGS    SS   TH S    +SG  +  ++   S G +Q  H   S  +SG G+ 
Sbjct: 721  PSTTSHGS---PSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 777

Query: 261  GSRSGQSSRGERHRSSSGSSSSYG-------QHGSGSRQSLGHGRQGS--GSRQSPSHVR 311
             + S  S+    H  SS  S++          H S    +  H    S    R   S   
Sbjct: 778  STTSHSSTT---HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIAS 834

Query: 312  HGSGSGHSSSHGQHGSGSSY---SYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGS 368
            H S     +      S +S      +     SGS +T+      +  G S   +   S  
Sbjct: 835  HSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSP 894

Query: 369  GHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQ 428
               ++     ST+    S     S SR  S++      S  + G  +HS+ S  SPG   
Sbjct: 895  RSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG--- 951

Query: 429  RGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHS 488
              + +   P+S    T      ++ P  SGS  ++        S  ++G ++  S + +S
Sbjct: 952  -STDTTLLPASTT--TXLVGEPTTSPISSGSTETTAL----PGSTTTAGLSEK-STTFYS 1003

Query: 489  SGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGS-------GSRQSLGHSRHGSGSGQSP 541
            S      + S  S+     G S  S++S+ + GS       GS    G S+  + S  SP
Sbjct: 1004 SPRSPDTTLSPASTTS--SGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSP 1061

Query: 542  SPSRGRHESGSRQSSSYGPHG--YGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQ 599
              +       S  +SS GP    + SG  S+       +  +SGL               
Sbjct: 1062 GSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGL--------------L 1107

Query: 600  HGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQS--SSHGQHGSGSSQSSRYGQQGSGSG 657
              S+  HSST     + S   S+  Q  +T+ QS  SS     +  + +S + +  + S 
Sbjct: 1108 EASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSH 1167

Query: 658  QSPSR------GRHGSDFGHS-SSYGQHGSGSGWSSSNGPHGSVSG----QSSGFGHKSG 706
             SPS           + FG S  S   H S    +++  P  S +     +S+ +    G
Sbjct: 1168 GSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPG 1227

Query: 707  SGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQS---- 762
            S Q    + H   SS +SG R   SR+  SS +    S    +S+  +  +  H S    
Sbjct: 1228 STQ----TMHFPESSTASG-RSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSI 1282

Query: 763  -----------SGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGS 811
                       SG   + + S  SP          H ++ G+    T+   S G  E+  
Sbjct: 1283 ATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTL 1342

Query: 812  GQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQS-SSYGQH 870
               +      + S   YS     S     Q    ++   SS SG+  S   Q+ S++   
Sbjct: 1343 ASTATTPGLSAKSTILYS-----SSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTA 1397

Query: 871  ESASHHASGRGRHGSGSGQSPGHGQR--GSGSGQSPSYGRHGS--GSGRSSSSGRHGSGS 926
              AS   SG  +  +     PG  +     GS  + S+ +  +   S   S+       S
Sbjct: 1398 FPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPAS 1457

Query: 927  GQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRS 964
                G   +S++  SS  +   +   HS++   H  +S
Sbjct: 1458 TTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQS 1495


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score =  126 bits (316), Expect = 3e-28
 Identities = 361/1563 (23%), Positives = 556/1563 (35%), Gaps = 189/1563 (12%)

Query: 286  HGSGSRQSLGHGRQGSGSRQSPSHVRHGSGS-----GHSSSHGQHGSGSSYSYSRGHYES 340
            H   S  + GH  + +    S +H +  + S      H+S H   GS  +  +      S
Sbjct: 2    HFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTIS 61

Query: 341  GSGQTSGFGQHESGSGQSSGYSKHGS--------------GSGHSSSQGQHGSTSGQASS 386
            G  + S    H S    ++     GS               SG   +    GST+    S
Sbjct: 62   GRSEESK-ASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLS 120

Query: 387  SGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPG--HGQRGSGSGQSPSSGQHGT 444
                   S   S    H  AS  SSG  + S+ S   PG  H     GS   P   Q  T
Sbjct: 121  EKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQEST 180

Query: 445  GFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSR------S 498
                +S S P  + +  S G              T    G  +++ H + GS        
Sbjct: 181  ----ASHSSPGPTDTTLSPG------------STTASSLGPEYTTFHSRPGSTETTLLPD 224

Query: 499  GQSSRGERQGSSAGSSSSYGQH------GSGSRQSLGHSRHGSGSGQSPSPSRGRHESG- 551
              ++ G  + S    SS+   H      GS +RQ    + H   S +   P+     S  
Sbjct: 225  NTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAF 284

Query: 552  ------SRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQES----RSGQSSGYGQHG 601
                  S  S S  P  + S RS++ G  E  + + S  G  ++     S  +SG G+  
Sbjct: 285  VEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEES 344

Query: 602  SSSGHSSTHGQHGSTSGQS----------SSCGQHGATSGQSSSHGQHGSGSSQSSRYGQ 651
            ++S  S+TH    + S  S          SS G    T    SS     S  S +S   Q
Sbjct: 345  TTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ 404

Query: 652  QGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSS 711
              +G+   P+R       G S++       SG   +    GS +  + G   +S +  SS
Sbjct: 405  DATGTIVLPARSTTSVLLGESTT---SPISSGSMETTALPGSTT--TPGLSERSTTFHSS 459

Query: 712  GYSQH---GSGSSHSSGYRKHG--SRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGH- 765
              S        S+ SSG  +    SRS   S        S  +    +H + SH S G  
Sbjct: 460  PRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 519

Query: 766  -----GRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCS----SSCGHYESGSGQASG 816
                     + SG S       SSSG + +    GS T+ S    S+  H   GS   + 
Sbjct: 520  DTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTL 579

Query: 817  FGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHH 876
            F    + SG       S   H S+     + S  SS+S       G+S+++  H +++H 
Sbjct: 580  FPDSTTSSG---IVEASTRVHSSTGSPRTTLSPASSTS---PGLQGESTAFQTHPASTHT 633

Query: 877  ASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGS---GSGQSSGFG 933
                    +   +      R  GS  +  +    + SG S  S    S    SG +    
Sbjct: 634  TPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSA 693

Query: 934  HKSSSGQSSGYTQHGS-GSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQ 992
            H ++SG+    T   S GS   ++     +  G S  S    SS  S ++       S  
Sbjct: 694  HSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT--TLSPASMT 751

Query: 993  SLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESG-SGHSSGLG 1051
            SLG G+  + S   P  +       S  +       S + +SSSRG  E+    HS+   
Sbjct: 752  SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSE-ESTTVYSSSRGSTETTVFPHST--- 807

Query: 1052 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQ 1111
               S  G+         +S H++   +  +TSG +    +  A  G  +S       +  
Sbjct: 808  -TTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTE---ESTAFPGSPASTQTGLPATLT 863

Query: 1112 SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHG----SGLGESSGF 1167
            ++  G + +    S G     +G++ SP+         RS++SG  G    S L  SS  
Sbjct: 864  TADLGEESTTFPSSSG----STGTKLSPA---------RSTTSGLVGESTPSRLSPSSTE 910

Query: 1168 GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSR 1227
                  S  + S S+  S + ++S      + S  ++     G S  SS+ + Q GS   
Sbjct: 911  TTTLPGSPTTPSLSEK-STTFYTSPRSPDATLSPATTTSS--GVSEESSTSHSQPGSTHT 967

Query: 1228 QSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQH 1287
             +       S     P+      G    S+      GS  +SS G  +S + HSS  G  
Sbjct: 968  TAFPDSTTTSDLSQEPTTSHSSQG----STEATLSPGSTTASSLG-QQSTTFHSSP-GDT 1021

Query: 1288 E----------SGSGHSSAYSQHGSGSGHFCSQGQHGSTSG---QSSTFDQEGSSTGQS- 1333
            E          SG   +S  +   +GS H        +++G   +S+TF    SS+  + 
Sbjct: 1022 ETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTP 1081

Query: 1334 SSYGHRGSGSSQSSGYGRHGAG------SGQSPSRGRHGSGSGHSSSYGQHGSG--SGWS 1385
            S  G   +    S+ Y    +       S  S + GR    +   SS G  G+      S
Sbjct: 1082 SPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRS 1141

Query: 1386 SSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGS 1445
            ++S   G  +      G  E+++   S  T   +G    S+      RS  ++      +
Sbjct: 1142 ATSVLVGEPTTSPISSGSTETTALPGSTTT---AGLSEKSTTFYSSPRSPDTTLSPASTT 1198

Query: 1446 SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSS 1505
            SSG S       S SR    H     GS   P  S+    S S   S+ +    GS  +S
Sbjct: 1199 SSGVSEE--STTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTAS 1256

Query: 1506 SRGPYESGSSHSSGLGHRESR----SGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQ 1561
            S GP ES + HSS  G  E+     +  +SG     S+  HSST   H + S   S+  Q
Sbjct: 1257 SLGP-ESTTFHSSP-GSTETTLLPDNTTASGL-LEASTPVHSSTGSPHTTLSPAGSTTRQ 1313

Query: 1562 HGASSGQS--SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR------ 1613
              +++ QS  SS     +  + +S +    + S  SP        S  S + GR      
Sbjct: 1314 GESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTT 1373

Query: 1614 -HGSGSGRS---SSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 1669
             H S    +   S +    SGL E S   H    S Q+  + +  + SG S       SR
Sbjct: 1374 VHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRS-----EESR 1428

Query: 1670 SGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHG 1729
            +  SS      S   ++S   +  +    S G          S + GR        SS  
Sbjct: 1429 TSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPD 1488

Query: 1730 QHG 1732
             +G
Sbjct: 1489 TNG 1491



 Score =  122 bits (307), Expect = 4e-27
 Identities = 357/1586 (22%), Positives = 576/1586 (36%), Gaps = 188/1586 (11%)

Query: 821  ESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGR 880
            ES +  G+S+  SA+ H S+     ST   +++       S   S+   H   S   SGR
Sbjct: 5    ESSTTSGHSEE-SATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGR 63

Query: 881  GRHGSGSGQSP-GHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGS---GSGQSSGFGHKS 936
                  S  SP         +G +PS     S     SS     +   GS    G   KS
Sbjct: 64   SEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKS 123

Query: 937  SSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGH 996
            ++  SS        S  ++      + SG S  S    S  GS+ +    GS +   L  
Sbjct: 124  TTFYSS------PRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLS- 176

Query: 997  GQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESR 1056
             Q  + S  SP P+      GS  +SS GP         +      GS  ++ L    + 
Sbjct: 177  -QESTASHSSPGPTDTTLSPGSTTASSLGP-------EYTTFHSRPGSTETTLLPDNTTA 228

Query: 1057 SGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQS--SSHGQHGSGSSQSSG 1114
            SG         S   HSST   H + S   S+  Q  +++  S  SS     +  + +S 
Sbjct: 229  SGL-----LEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSA 283

Query: 1115 YGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSG----QHGSGLGESSGFGHH 1170
            +    + S  SP        S +S + G     +   SS G     H      +SG G  
Sbjct: 284  FVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 343

Query: 1171 ESSSGQSSSYSQHGSGSGHSSGYGQHGS-RSGQSSRGERHGSSSGSSSHYGQHGSGSRQS 1229
             ++S  S++++   + S  S+   +  S  S   S    H   S ++S   +  + S  S
Sbjct: 344  STTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS 403

Query: 1230 SGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHES 1289
                +  +G+   P+R      LG S++     SGS  +++     +  G S       S
Sbjct: 404  ----QDATGTIVLPARSTTSVLLGESTT-SPISSGSMETTALPGSTTTPGLS-----ERS 453

Query: 1290 GSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGY 1349
             + HSS  S   + S          ST+    + +   S +   S++      S+ + G 
Sbjct: 454  TTFHSSPRSPATTLS--------PASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGL 505

Query: 1350 GRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSS---GFGHHES 1406
             RH   S  SP       GS  ++      + SG S  S    S SG +      G   +
Sbjct: 506  SRHSTTSHSSP-------GSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTA 558

Query: 1407 SSWQSSGCTQHGS-GSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLG 1465
             S+     T H + GS H++ +    + SG      R  SS+GS  +     S    S  
Sbjct: 559  LSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPAS----STS 614

Query: 1466 HGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRG--PYESGSSHSSGLGHR 1523
             G  G  +     P+   H + S  S++ +P    + +  S G  P     + S+  GH 
Sbjct: 615  PGLQGESTAFQTHPA-STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHS 673

Query: 1524 ESRSGQSSGYGQHGS--SSGHSSTHGQHGSTSGQSS-----------SCGQHGASSGQSS 1570
            E  +   S     G+  SS HS+T G+  ST+ + S           S    G S   ++
Sbjct: 674  EKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTT 733

Query: 1571 SHGQHGS-------GSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSS 1623
             +    S        S  S G G + + S   PG     + S  SP+       S  S++
Sbjct: 734  FYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG----STHSTVSPASTTTPGLSEESTT 789

Query: 1624 SGQHGSGLGESSGFGHHESSS--GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGS 1681
                  G  E++ F H  ++S  G+  +       S H++ + +  + SG +        
Sbjct: 790  VYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPG 849

Query: 1682 SSRS----------SSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQH 1731
            S  S          ++  G+  +    SSG     +G+  SP+R      +G S+     
Sbjct: 850  SPASTQTGLPATLTTADLGEESTTFPSSSG----STGTKLSPARSTTSGLVGESTPSRLS 905

Query: 1732 GSGSGRSSSRGP-------------YES-RSGHSSVFGQHESGSGHSSAYSQHGSGSGHF 1777
             S +  ++  G              Y S RS  +++     + SG S   S   S  G  
Sbjct: 906  PSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGST 965

Query: 1778 CSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGS 1837
             +     ST+    + +   S + Q S+      GS+ +SS GQQ +    SP       
Sbjct: 966  HTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTL 1025

Query: 1838 GSGHSSSYGQHGSGSGWSSSSGRHGS----GSGQSSGFGHHESSSWQSSGYTQHGSGSGH 1893
                + + G   + +   SS+G   +     S  S+G    ES+++QS            
Sbjct: 1026 LPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGL-QEESTTFQS-----------W 1073

Query: 1894 SSSYEQHGSRSGQSSRGEQHGSS--SGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR 1951
             SS +   S  G ++   +  ++  S  SS+   H S S  +LG  +  +    SP    
Sbjct: 1074 PSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP---- 1129

Query: 1952 GRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG 2011
            G  G+    + S      G   +S   P  SGS  ++ L    + +G S       S++ 
Sbjct: 1130 GATGTALFPTRSATSVLVGEPTTS---PISSGSTETTALPGSTTTAGLS-----EKSTTF 1181

Query: 2012 HSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQR 2071
            +SS      + S  S++    G S   ++SH + GS  + +        GS   PG  Q 
Sbjct: 1182 YSSPRSPDTTLSPASTT--SSGVSEESTTSHSRPGSTHTTAF------PGSTTMPGVSQE 1233

Query: 2072 GSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSS 2131
             + S  SP     GS     S        LG  S   H    S +++    + + SG   
Sbjct: 1234 STASHSSP-----GSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGL-- 1286

Query: 2132 GYGQHGSRSGQSSRGERHG--SSSGSSSRYG-----QHGSGSRQSSGHGRQGSGSGHSPS 2184
                  S    SS G  H   S +GS++R G     Q    S+ +       + +    S
Sbjct: 1287 ---LEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELS 1343

Query: 2185 RGRHGSGSGHSSSHGQHGSGS-GRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSG 2243
               HGS S   ++H    S + GRS      ES + HSS      + S   S  S  G  
Sbjct: 1344 TTSHGSPSSTPTTHFSASSTTLGRSE-----ESTTVHSSPVATATTPSPARSTTS--GLV 1396

Query: 2244 SGHFCSQGQHGSTSGQSSTFDQEGSSTGQS-SSHGQHGSGSSQSSSYGQQGSGSGQSPSR 2302
                      GST  Q+  F +  +++G+S  S   H S +   SS     S   + P+ 
Sbjct: 1397 EESTAYHSSPGST--QTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTS 1454

Query: 2303 GRHGSGSGHSSSYGQHGSGSGWSSSS 2328
                 GS  ++ + +  + SG S  S
Sbjct: 1455 YHSSPGSIATTHFPESSTTSGRSEES 1480



 Score =  113 bits (282), Expect = 3e-24
 Identities = 349/1525 (22%), Positives = 520/1525 (34%), Gaps = 225/1525 (14%)

Query: 1063 YGQHGSSSGHSSTHGQ-HGSTSGQSSSCGQHGASSGQSSSHGQHGS-------GSSQSSG 1114
            + +  ++SGHS      HGST+   SS     A+   +S H   GS        SS  SG
Sbjct: 3    FPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISG 62

Query: 1115 YGRQGSGSGQSPGHGQRG---SGSRQSPSYGRHGSG---SGRSSSSGQHGS----GLGES 1164
               +   S  SP         +GS  S   G        SG   ++   GS    GL E 
Sbjct: 63   RSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEK 122

Query: 1165 SGFGHHE-------------SSSGQS--SSYSQHGSGSGHSSGYGQHGSRSGQSSRGERH 1209
            S   +               +SSG S  S+ S    GS H++ +    +  G S      
Sbjct: 123  STTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTAS 182

Query: 1210 GSSSGSSSHYGQHGSGSRQSSG------HGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGS 1263
             SS G +      GS +  S G      H R GS            SGL  +S       
Sbjct: 183  HSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASM------ 236

Query: 1264 GSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHG-----SGSGHFC--SQGQHGST 1316
                SS+R P+ + S   S   Q ES + HS   S+       + +  F   S   HGS 
Sbjct: 237  -PVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSP 295

Query: 1317 SGQSSTFDQEGSSTG----QSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHS 1372
            S   +T     S+T     +S++Y H   GS+Q+  +      SG+        S + H+
Sbjct: 296  SSIPTTHISARSTTSGLVEESTTY-HSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHT 354

Query: 1373 SSYGQHGSGSGWSSSSGRHGS-GSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHG 1431
             S     + +     +  H S GS  ++ F    ++S +S   T   S    + +     
Sbjct: 355  ISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPA 414

Query: 1432 SRSGQSSRGERHGS--SSGSSSSYGQHGSGSRQSLGH-------------------GQHG 1470
              +     GE   S  SSGS  +    GS +   L                         
Sbjct: 415  RSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTS 474

Query: 1471 SGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQS 1530
            SG  +  + SR R GS    +   S    G    S+      GS+ ++ L    + SG S
Sbjct: 475  SGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPS 534

Query: 1531 SGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGY----G 1586
                   SSSG + T    GST+  S         S   S+H      S+ SSG      
Sbjct: 535  QESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEAST 594

Query: 1587 RQGSGSGQ-----SPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHE 1641
            R  S +G      SP          +S ++  H + +  + S     +   E S   H  
Sbjct: 595  RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRS 654

Query: 1642 SSSGQSSSYSQHGSGSGHS------------SGYGQHGSRSGQSSRGE------------ 1677
              S  ++ +    + SGHS            SG     + S  S RGE            
Sbjct: 655  PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE 714

Query: 1678 ---------RHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSH 1728
                       G S  S++ Y    S +   S       G G+  +  R   G  HS+  
Sbjct: 715  ITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS 774

Query: 1729 GQHGSGSGRSSSRGPYESRSGHSSVFGQHESG-SGHSSAYSQHGSGSGHFCSQGQHGSTS 1787
                +  G S      ES + +SS  G  E+    HS+  S HG     F     H   +
Sbjct: 775  PASTTTPGLSE-----ESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTF-----HSRPA 824

Query: 1788 GQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQ 1847
               +T   E S+T   +       GS  S+  G   + +          +  G  S+   
Sbjct: 825  STHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLT---------TADLGEESTTFP 875

Query: 1848 HGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQ----HGSR 1903
              SGS  +  S    + SG          S   +   T  GS +  S S +        R
Sbjct: 876  SSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPR 935

Query: 1904 SGQSSRGEQHGSSSG----SSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSG 1959
            S  ++      +SSG    SS+S+ Q GS    +       S   Q P+ S    GS   
Sbjct: 936  SPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEA 995

Query: 1960 QSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQH 2019
              S      S  G  S+      G   ++ L      SG         S+  HSST   H
Sbjct: 996  TLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGL-----VEASTPTHSSTGSLH 1050

Query: 2020 GSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSP 2079
             + +  SS+     A   + S+  Q    SS ++       G+  +P        SR S 
Sbjct: 1051 TTLTPASST----SAGLQEESTTFQSWPSSSDTT---PSPPGTTAAPVEVSTTYHSRPSS 1103

Query: 2080 SYGRHGSGS----GRS--SSSGQHGPGLGESSGFGHHESSS---GQSSSYSQHGSGSGHS 2130
            +   H S S    GRS  S++    PG   ++ F    ++S   G+ ++ S   SGS  +
Sbjct: 1104 TPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTT-SPISSGSTET 1162

Query: 2131 SGYGQHGSRSGQSSRGERHGSSSGSS----SRYGQHGSGSRQSSGHGRQGSGSGHSP--- 2183
            +      + +G S +     SS  S     S      SG  + S       GS H+    
Sbjct: 1163 TALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP 1222

Query: 2184 -SRGRHGSGSGHSSSHGQHGS-------GSGRSSSRGPYESRSGHSS-------VFGQHE 2228
             S    G     ++SH   GS       GS  +SS GP ES + HSS       +   + 
Sbjct: 1223 GSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGP-ESTTFHSSPGSTETTLLPDNT 1281

Query: 2229 SGSGHSSAYSQ-HGSGSGHFCSQGQHGSTS--GQSSTFDQEGSSTG-------------- 2271
            + SG   A +  H S      +    GST+  G+S+TF    SS                
Sbjct: 1282 TASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVE 1341

Query: 2272 -QSSSHGQ-------HGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSG 2323
              ++SHG        H S SS +    ++ +    SP           S++ G     + 
Sbjct: 1342 LSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTA 1401

Query: 2324 WSSSSG----RHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGS-RSGQSS 2378
            + SS G     H   S  +SG      +S  S+ +T     S  S+  E+  S  S   S
Sbjct: 1402 YHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGS 1461

Query: 2379 RGERHGSSSGSSSSYGQHGSGSRQS 2403
                H   S ++S   +  + S  S
Sbjct: 1462 IATTHFPESSTTSGRSEESTASHSS 1486



 Score =  106 bits (265), Expect = 3e-22
 Identities = 342/1582 (21%), Positives = 549/1582 (34%), Gaps = 216/1582 (13%)

Query: 1294 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHG 1353
            SS  S H   S  F     HGST+   S+     ++   +S   H   GS++++ +    
Sbjct: 6    SSTTSGHSEESATF-----HGSTTHTKSSTPSTTAALAHTSY--HSSLGSTETTHFRDSS 58

Query: 1354 AGSGQSP-SRGRHGSGSGHSSSYGQHGSGSG---WSSSSGRHGSGSGQSSGFGHHESSSW 1409
              SG+S  S+  H S    +++    GS        S+     SGS +++      +   
Sbjct: 59   TISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPG 118

Query: 1410 QSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQH 1469
             S   T   S      +     S +      E   S S   S++     GS    G  Q 
Sbjct: 119  LSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQE 178

Query: 1470 GSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQ 1529
             + S  SP P+      GS  +SS  P         +      GS+ ++ L    + SG 
Sbjct: 179  STASHSSPGPTDTTLSPGSTTASSLGP-------EYTTFHSRPGSTETTLLPDNTTASGL 231

Query: 1530 -SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQ-----------------SSS 1571
              +    H S+    +T    GST+ Q  S   H   S +                 ++S
Sbjct: 232  LEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTS 291

Query: 1572 HGQ-------HGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSS 1624
            HG        H S  S +SG   + +    SPG  Q         + GR G  S  S SS
Sbjct: 292  HGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGR-GEESTTSHSS 350

Query: 1625 GQH--GSGLGESSGFGHHESS--SGQSSSYSQHGSGSGHSSGYGQHG--SRSGQSSRGER 1678
              H   S    +S      +S  S   S+ + H   S  +SG  +    S S Q + G  
Sbjct: 351  TTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTI 410

Query: 1679 HGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRS 1738
               +  ++S      + S  SSG     +  G + + G                S +  S
Sbjct: 411  VLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGL------------SERSTTFHS 458

Query: 1739 SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGS 1798
            S R P  + S  S+      SG    S  S+   GS H         T+    +    G 
Sbjct: 459  SPRSPATTLSPASTT----SSGVSEESTTSRSRPGSTH---------TTAFPDSTTTPGL 505

Query: 1799 STGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSS 1858
            S   ++SH   GS  +         SG  Q        S + HSSS           S+ 
Sbjct: 506  SRHSTTSHSSPGSTDTTLLPASTTTSGPSQE-------STTSHSSS----------GSTD 548

Query: 1859 GRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSG 1918
                 GS  +  FG  ES+++ S+       GS H++ +    + SG      +  SS+G
Sbjct: 549  TALSPGSTTALSFGQ-ESTTFHSN------PGSTHTTLFPDSTTSSGIVEASTRVHSSTG 601

Query: 1919 SSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRG 1978
            S  +     S    S   G  G  +     P+   H + S  S++  P    + +  S G
Sbjct: 602  SPRTTLSPAS----STSPGLQGESTAFQTHPA-STHTTPSPPSTATAPVEESTTYHRSPG 656

Query: 1979 --PYESGSGHSSGLGHRESRSGQSSGYGQHGS--SSGHSSTHGQHGSASGQSSSCGQH-- 2032
              P       S+  GH E  +   S     G+  SS HS+T G+  S + + S       
Sbjct: 657  STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT 716

Query: 2033 ---GASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG 2089
               G+++    S       SS  S        S  S G G+  + SR  P     GS   
Sbjct: 717  TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQP-----GSTHS 771

Query: 2090 RSSSSGQHGPGLGESSGFGHHESSSG-------QSSSYSQHGS---------GSGHSSGY 2133
              S +    PGL E S   +  S           S++ S HG           S H++ +
Sbjct: 772  TVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLF 831

Query: 2134 GQHGSRSGQSSRGERHGSSSGSSSR----------YGQHGSGSRQSSGHGRQGSGSGHSP 2183
             +  + SG +        S  S+             G+  +    SSG     +G+  SP
Sbjct: 832  TEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSG----STGTKLSP 887

Query: 2184 SRGRHGSGSGHSSSHGQHGSGSGRSSSRGP-------------YES-RSGHSSVFGQHES 2229
            +R       G S+      S +  ++  G              Y S RS  +++     +
Sbjct: 888  ARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTT 947

Query: 2230 GSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSY 2289
             SG S   S   S  G   +     ST+    + +   S + Q S+      GS+ +SS 
Sbjct: 948  SSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSL 1007

Query: 2290 GQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS----GSGQSSGFGHHE 2345
            GQQ +    SP           + + G   + +   SS+G   +     S  S+G     
Sbjct: 1008 GQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEES 1067

Query: 2346 SS--SWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQS 2403
            ++  SW SS  T        ++  E   +              S  SS+   H S S  +
Sbjct: 1068 TTFQSWPSSSDTTPSPPGTTAAPVEVSTTYH------------SRPSSTPTTHFSASSTT 1115

Query: 2404 LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHR 2463
            LG  +  +    SP    G  G+    + S +    G   +S   P  SGS  ++ L   
Sbjct: 1116 LGRSEESTTVHSSP----GATGTALFPTRSATSVLVGEPTTS---PISSGSTETTALPGS 1168

Query: 2464 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSS 2523
             + +G S       SS     T     ST+    S     + S   S+H     GS+   
Sbjct: 1169 TTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP 1228

Query: 2524 GYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESS 2583
            G  ++ + S  SPG     + +  SP      S  G  S++     G  E++    + ++
Sbjct: 1229 GVSQESTASHSSPG----STDTTLSPG-STTASSLGPESTTFHSSPGSTETTLLPDNTTA 1283

Query: 2584 SG--QSSSYSQHGSGSGHSS-GYGQHGSRSGQSSRGERHGSSSG-------SSSHYGQ-- 2631
            SG  ++S+     +GS H++       +R G+S+  +   SS         ++S + +  
Sbjct: 1284 SGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELS 1343

Query: 2632 ---HGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRL 2688
               HGS S   + H    S S  +  R    + +  S           RS++ G  E   
Sbjct: 1344 TTSHGSPSSTPTTH---FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEEST 1400

Query: 2689 GHSSVFGQHESGSGHSSAYSQHGSGSGHF-CSQGQHGSTSGQSSTFDQEGSSTGQSSSYG 2747
             + S       GS  +  + +  + SG    S+  H ST+   S+     S+  +  +  
Sbjct: 1401 AYHS-----SPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSY 1455

Query: 2748 HRGSGSSQSSGYGRHGAGSGQS 2769
            H   GS  ++ +      SG+S
Sbjct: 1456 HSSPGSIATTHFPESSTTSGRS 1477



 Score = 97.4 bits (241), Expect = 2e-19
 Identities = 297/1329 (22%), Positives = 467/1329 (35%), Gaps = 180/1329 (13%)

Query: 203  PNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQ--HGSGSGHSSGYGQH 260
            P+   HGS    SS   TH S    +SG  +  ++   S G +Q  H   S  +SG G+ 
Sbjct: 287  PSTTSHGS---PSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 343

Query: 261  GSRSGQSSRGERHRSSSGSSSSYG-------QHGSGSRQSLGHGRQGS--GSRQSPSHVR 311
             + S  S+    H  SS  S++          H S    +  H    S    R   S   
Sbjct: 344  STTSHSSTT---HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTAS 400

Query: 312  HGSGSGHSSSHGQHGSGSSY---SYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGS 368
            H S     +      S +S      +     SGS +T+      +  G S   +   S  
Sbjct: 401  HSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSP 460

Query: 369  GHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQ 428
               ++     ST+    S     S SR  S++      S  + G  +HS+ S  SPG   
Sbjct: 461  RSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTD 520

Query: 429  RGSGSGQSPSSGQHGTGFGRSSSSG----PYVSGSGYSSGFGHHESSSEHSSGYTQHGS- 483
                   + +SG         SSSG        GS  +  FG  ES++ HS+  + H + 
Sbjct: 521  TTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFG-QESTTFHSNPGSTHTTL 579

Query: 484  --GSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSP 541
               S  SSG  +  +R   S+   R   S  SS+S G  G    +S     H + +  +P
Sbjct: 580  FPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQG----ESTAFQTHPASTHTTP 635

Query: 542  SPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHG 601
            SP      +   +S++Y        RS    P       S+  GH E  +   S     G
Sbjct: 636  SPP-STATAPVEESTTY-------HRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASG 687

Query: 602  S--SSGHSSTHGQHGSTSGQSS-----------SCGQHGATSGQSSSHGQHGSGSSQSSR 648
            +  SS HS+T G+  ST+ + S           S    G +   ++ +    S ++  S 
Sbjct: 688  TTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSP 747

Query: 649  YGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSG--------WSSSNG-------PHG- 692
                  G G+  +  R      HS+      +  G        +SSS G       PH  
Sbjct: 748  ASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHST 807

Query: 693  --SVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSS 750
              SV G+     H   S  +S ++   +  S +SG  +  +    S  S Q G  + L++
Sbjct: 808  TTSVHGEEPTTFH---SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTT 864

Query: 751  S-YGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCG---- 805
            +  G+  +    SSG     +G+  SP+R       G S+      S T  ++  G    
Sbjct: 865  ADLGEESTTFPSSSG----STGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTT 920

Query: 806  ------------HYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSS 853
                           S     S      SG  +  S   S  G   +     ST+    S
Sbjct: 921  PSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLS 980

Query: 854  SGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGS 913
                 S S Q S+       S  AS  G+  +    SPG  +       + + G   + +
Sbjct: 981  QEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEAST 1040

Query: 914  GRSSSSGRHGS----GSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 969
               SS+G   +     S  S+G   +S++ QS             SS +   S  G ++ 
Sbjct: 1041 PTHSSTGSLHTTLTPASSTSAGLQEESTTFQS-----------WPSSSDTTPSPPGTTAA 1089

Query: 970  SEQHGSS--SGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPY 1027
              +  ++  S  SS+   H S S  +LG  +           S   H S     ++  P 
Sbjct: 1090 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEE----------STTVHSSPGATGTALFPT 1139

Query: 1028 RSGSG---WSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSG 1084
            RS +       +  P  SGS  ++ L    + +G S       S++ +SS      + S 
Sbjct: 1140 RSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLS-----EKSTTFYSSPRSPDTTLSP 1194

Query: 1085 QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 1144
             S++    G S   ++SH + GS  + +        GS   PG  Q  + S  SP     
Sbjct: 1195 ASTT--SSGVSEESTTSHSRPGSTHTTAF------PGSTTMPGVSQESTASHSSP----- 1241

Query: 1145 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 1204
            GS     S      S LG  S   H    S +++    + + SG         S    SS
Sbjct: 1242 GSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGL-----LEASTPVHSS 1296

Query: 1205 RGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSG 1264
             G  H + S +       GS +RQ    G   +      S+    +    +S+  +  + 
Sbjct: 1297 TGSPHTTLSPA-------GSTTRQ----GESTTFQSWPSSKDTMPAPPTTTSAFVELSTT 1345

Query: 1265 SGRSSSRGPYESRSGHSSVFGQ-HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF 1323
            S  S S  P    S  S+  G+  ES + HSS                   +T+   S  
Sbjct: 1346 SHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPV-----------------ATATTPSPA 1388

Query: 1324 DQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQS-PSRGRHGSGSGHSSSYGQHGSGS 1382
                S   + S+  H   GS+Q+  +      SG+S  SR  H S +   SS     S  
Sbjct: 1389 RSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSAL 1448

Query: 1383 GWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCT-QHGSGSGHS-SSYEQHGSRSGQSSRG 1440
                +S     GS  ++ F    ++S +S   T  H S   +  +    H + SG+ +  
Sbjct: 1449 VEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAES 1508

Query: 1441 ERHGSSSGS 1449
                 S GS
Sbjct: 1509 TTFYISPGS 1517



 Score = 75.9 bits (185), Expect = 5e-13
 Identities = 217/941 (23%), Positives = 333/941 (35%), Gaps = 152/941 (16%)

Query: 1884 YTQHGSGSGHSS-SYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGS-GSRQSLGHGQHGS 1941
            + +  + SGHS  S   HGS +   S      S++ + +    H S GS ++       +
Sbjct: 3    FPESSTTSGHSEESATFHGSTTHTKSSTP---STTAALAHTSYHSSLGSTETTHFRDSST 59

Query: 1942 GSGQSPSPSRGRHGSGSGQSSSYGPYGSGSG---WSSSRGPYESGSGHSSGLGHRESRSG 1998
             SG+S   S+  H S    +++  P GS        S+  P  SGS  ++ L    ++ G
Sbjct: 60   ISGRSEE-SKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPG 118

Query: 1999 QSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 2058
             S       SS     T   H  AS  SS     G S   ++SH + GS  + +      
Sbjct: 119  LSEKSTTFYSSPRSPDT--THLPASMTSS-----GVSEESTTSHSRPGSTHTTAF----- 166

Query: 2059 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSS 2118
              GS   PG  Q  + S  SP         G +++S      LG      H    S +++
Sbjct: 167  -PGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASS-----LGPEYTTFHSRPGSTETT 220

Query: 2119 SYSQHGSGSG--------HSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGS-GSRQS 2169
                + + SG        HSS    H + S            +GS++R G+  +  S  S
Sbjct: 221  LLPDNTTASGLLEASMPVHSSTRSPHTTLS-----------PAGSTTRQGESTTFHSWPS 269

Query: 2170 SGHGRQGSGSGHS----PSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFG 2225
            S   R    +  S    PS   HGS S   ++H      S RS++ G  E          
Sbjct: 270  SKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHI-----SARSTTSGLVE---------- 314

Query: 2226 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQ 2285
              ES + HSS  S     + HF    +  +TSG+      E S+T  SS+     S  S 
Sbjct: 315  --ESTTYHSSPGSTQ---TMHF---PESDTTSGRG-----EESTTSHSSTTHTISSAPST 361

Query: 2286 SSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHE 2345
            +S+  ++ +    SP       GS  ++ +    + SG S  S    S    +       
Sbjct: 362  TSALVEEPTSYHSSP-------GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPA 414

Query: 2346 SSSWQ----SSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSR 2401
             S+       S  +   SGS  +++     +  G S R     SS  S ++     S + 
Sbjct: 415  RSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTT- 473

Query: 2402 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLG 2461
                     SG  +  + SR R GS    +   S    G    S+      GS  ++ L 
Sbjct: 474  --------SSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP 525

Query: 2462 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQ 2521
               + SG S       SSSG + T    GST+  S         S   S+H      S+ 
Sbjct: 526  ASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTT 585

Query: 2522 SSGY----GRQGSGSGQ-----SPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLG 2572
            SSG      R  S +G      SP          +S ++  H + +  + S     +   
Sbjct: 586  SSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPV 645

Query: 2573 ESSGFGHHESSSGQSSSYSQHGSGSGHS------------SGYGQHGSRSGQSSRGE--- 2617
            E S   H    S  ++ +    + SGHS            SG     + S  S RGE   
Sbjct: 646  EESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT 705

Query: 2618 ------------------RHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHG 2659
                                G S  S++ Y    S +   S       G G+  +  R  
Sbjct: 706  SRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQ 765

Query: 2660 SGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESG-SGHSSAYSQHGSGSGHFC 2718
             G  HS+      +  G S      ES   +SS  G  E+    HS+  S HG     F 
Sbjct: 766  PGSTHSTVSPASTTTPGLSE-----ESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFH 820

Query: 2719 SQGQHGSTSGQSSTFDQEGSSTG-QSSSYGHRGSGSSQSSG 2758
            S+      S  ++ F ++ +++G    S    GS +S  +G
Sbjct: 821  SR----PASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTG 857



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 141/635 (22%), Positives = 228/635 (35%), Gaps = 80/635 (12%)

Query: 2234 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQG 2293
            SS  S H   S  F     HGST+   S+     ++   +S H     GS++++ +    
Sbjct: 6    SSTTSGHSEESATF-----HGSTTHTKSSTPSTTAALAHTSYHSS--LGSTETTHFRDSS 58

Query: 2294 SGSGQSP-SRGRHGSGSGHSSSYGQHGS--------------GSGWSSSSGRHGSG---- 2334
            + SG+S  S+  H S    +++    GS               SG   ++   GS     
Sbjct: 59   TISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPG 118

Query: 2335 ---------SGQSSGFGHHESSSWQSSGYTQHGS------GSGHSSSYEQHGSRSGQSSR 2379
                     S   S    H  +S  SSG ++  +      GS H++++    +  G S  
Sbjct: 119  LSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQE 178

Query: 2380 GERHGSSSGSSSSYGQHGSGSRQSLG------HGQHGSGSG----QSPSPSRGRHGSGSG 2429
                 SS G + +    GS +  SLG      H + GS        + + S     S   
Sbjct: 179  STASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPV 238

Query: 2430 QSSSYSPYGSGSGWSSSRGPYESGSGHS--SGLGHRESRSGQSSGYGQ-----HGSSSGH 2482
             SS+ SP+ + S   S+    ES + HS  S    R +    +S + +     HGS S  
Sbjct: 239  HSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSI 298

Query: 2483 SSTH-GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQR 2541
             +TH     +TSG       + +S G  S+   H   S  +SG G + + S  S  H   
Sbjct: 299  PTTHISARSTTSGLVEESTTYHSSPG--STQTMHFPESDTTSGRGEESTTSHSSTTHTIS 356

Query: 2542 GSGSRQSPSYGRHGS-GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 2600
             + S  S       S  S   S++  H      +SG     S    +S  SQ  +G+   
Sbjct: 357  SAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSG----RSEESTASHSSQDATGTIVL 412

Query: 2601 SGYGQHGSRSGQSSRGERHGSSSGSSSHYGQH---GSGSRQSSGHGRQGSGSGQSPSRGR 2657
                      G+S+       S  +++  G     G   R ++ H    S +        
Sbjct: 413  PARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPAST 472

Query: 2658 HGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHS--SVFGQHESGSGHSSAYSQHGSGSG 2715
              SG+   S+  +   GS  +++     +  G S  S       GS  ++      + SG
Sbjct: 473  TSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 532

Query: 2716 HFCSQGQHGSTSGQSSTFDQEGSST----GQSSSYGHRGSGSSQSSGYGRHGAGSG---- 2767
                     S+SG + T    GS+T    GQ S+  H   GS+ ++ +      SG    
Sbjct: 533  PSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEA 592

Query: 2768 QSLSHGRHGSGSGQSSSYGQHGSG-SGQSSGYSQH 2801
             +  H   GS     S       G  G+S+ +  H
Sbjct: 593  STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTH 627


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo
            sapiens]
          Length = 2231

 Score =  119 bits (299), Expect = 3e-26
 Identities = 335/1548 (21%), Positives = 492/1548 (31%), Gaps = 201/1548 (12%)

Query: 773  GHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHG 832
            G +P+   H     H  +H  H      +    H+ +   Q + F Q +    Q   Q  
Sbjct: 15   GEAPAAPPHQQHHHHHHAHHHHHH----AHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQ 70

Query: 833  SASGHFSSQGRHGSTSG----------QSSSSGQHDSSSGQS---------SSYGQHESA 873
                  S+    G   G          Q    G  DS++G           S  G  + A
Sbjct: 71   QQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDA 130

Query: 874  SHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSS---SGRHGSGSGQSS 930
                   G    G  + PG G  G+   Q P     G G G ++    +  +GS +  S 
Sbjct: 131  PPKM---GEPAGGRYEHPGLGALGT---QQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG 184

Query: 931  GFGHKSSS--GQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGS 988
            G G ++     Q  G    G G  HS+S    G+          H    G  +S   H  
Sbjct: 185  GPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSH---EGYPNSQCNHYP 241

Query: 989  G-SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHS 1047
            G SR   G G  G G G          G GSG     G   +G   + +     + +  +
Sbjct: 242  GYSRPGAGGGGGGGGGG----------GGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAA 291

Query: 1048 SGLGHRESRSGQSSGYGQHGS----SSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHG 1103
            +G G      G S+GYG   S      G     G  G+ S   ++ G       + +   
Sbjct: 292  AGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQN 351

Query: 1104 QHGSGSSQS------SGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH 1157
            QH SG++ +      S      S  G  P +    +            + +G ++   Q 
Sbjct: 352  QHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQA 411

Query: 1158 GSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSS 1217
             +G+G     G   +++  + + +Q  S    S G    G   G+S              
Sbjct: 412  AAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPG--TPGPTMGRSQGSPMDPMVMKRPQ 469

Query: 1218 HYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESR 1277
             YG   +   Q         GS   P   R+  G+   +     G+ +G    +     +
Sbjct: 470  LYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTP----GAMAGMQYPQQQMPPQ 525

Query: 1278 SGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYG 1337
             G   V G  + G      YSQ      H   Q Q+  +  Q     Q+  S      YG
Sbjct: 526  YGQQGVSGYCQQGQ--QPYYSQQPQPP-HLPPQAQYLPSQSQQRYQPQQDMS---QEGYG 579

Query: 1338 HRGSGSSQSSGYGRH---GAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 1394
             R S    + G   H        + PS     SGS      G   + S   S+SG   S 
Sbjct: 580  TR-SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQ 638

Query: 1395 SGQS----SGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSS 1450
              QS    S F  H S     S      S S   S    + SRSG  S     GS     
Sbjct: 639  GDQSNPAQSPFSPHASP--HLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQ 696

Query: 1451 SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYG-SGSGWSSSRGP 1509
                Q  S S  +L          QSP P      +G+ ++   + YG   +G S S  P
Sbjct: 697  PPGSQSESSSHPALS---------QSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHP 747

Query: 1510 YESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSG-QSSSCGQHGASSGQ 1568
               G  H+     ++S S  S  YG   S  G    + +  + SG  S+S    G   G 
Sbjct: 748  SPGGQMHAGISSFQQSNS--SGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGI 805

Query: 1569 SSSHGQHGSGSSQSSG---YGRQGSGSGQS-PGHGQRGSGSRQSPSYGRHGSGSGRSSSS 1624
            S+++  HG G SQ  G    GR  S   Q+ P  G   S +  SP   + G G G     
Sbjct: 806  SANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQG-GPGM---- 860

Query: 1625 GQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSR 1684
               G  +   +      +++   ++ +   S  G   G  Q G  +  S   +   +SS 
Sbjct: 861  ---GPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSS 917

Query: 1685 SSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPY 1744
              +      S +           G     S G     L   +   + G+    S S+  Y
Sbjct: 918  LMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSY 977

Query: 1745 ESRS-------GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG-QSSTFDQE 1796
             S+        G+  V       S   S++  HG  S    S G   + S  +SS+    
Sbjct: 978  SSQGISQPPTPGNLPVPSPMSPSSASISSF--HGDESDSISSPGWPKTPSSPKSSSSTTT 1035

Query: 1797 GSSTGQSSSHGQHGSGSSQSSSY----GQQGSGSGQSPSRGRHGSGS-------GHSSSY 1845
            G    +    G           Y     ++GS     P+ G+                  
Sbjct: 1036 GEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGL 1095

Query: 1846 GQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSG------SGHSSSYEQ 1899
             Q      W   +     G+  S+       +S     Y Q+          G     E 
Sbjct: 1096 AQVNKNKKWRELATNLNVGTSSSA-------ASSLKKQYIQYLFAFECKIERGEEPPPEV 1148

Query: 1900 HGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSG--QSPSPSRGRHGSG 1957
              +   +     Q  S + S S  G     + QS G        G  + P+P+   HG  
Sbjct: 1149 FSTGDTKKQPKLQPPSPANSGSLQGPQ---TPQSTGSNSMAEVPGDLKPPTPASTPHGQM 1205

Query: 1958 S----GQSSSYGPYGSGSGWSSS----------RGPYESGSGHSSGLGHR--ESRSGQSS 2001
            +    G+SS+   +   S  S S            PY+ G      +G    E       
Sbjct: 1206 TPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFG 1265

Query: 2002 GYGQHGSSSGHSSTHGQHGSAS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG 2056
            G  +   SS    T GQ  ++S      QS S        GQ        S   +   YG
Sbjct: 1266 GMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYG 1325

Query: 2057 RQ----GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHH-E 2111
            +Q    G  SGQ P  G +     Q P+Y RH          G +GP      G  ++ +
Sbjct: 1326 QQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRH--------MDGMYGPPAKRHEGDMYNMQ 1377

Query: 2112 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSG 2171
             SS Q   Y+Q+G            GS SG   R    G      SR    G G  Q+ G
Sbjct: 1378 YSSQQQEMYNQYG------------GSYSGPDRR-PIQGQYPYPYSRERMQGPGQIQTHG 1424

Query: 2172 HGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSG 2219
               Q  G          G     SS   Q    + R+    PY++R G
Sbjct: 1425 IPPQMMG----------GPLQSSSSEGPQQNMWAARNDMPYPYQNRQG 1462



 Score =  105 bits (262), Expect = 6e-22
 Identities = 320/1442 (22%), Positives = 484/1442 (33%), Gaps = 233/1442 (16%)

Query: 468  HESSSEHSSGYTQHGSGS-GHSSGHGQHGSRSGQSSRGE----------RQGSSAGSSSS 516
            H  S+ +S G    G+   G      QHG     ++ G+          + G    +   
Sbjct: 74   HPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPK 133

Query: 517  YGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES 576
             G+   G  +  G    G+       P  G   +   + ++Y    YGS   +S GP   
Sbjct: 134  MGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNY----YGSAAPASGGP--- 186

Query: 577  GSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSH 636
              G  +G    +    QS G G   S+S               +++ G  G+     +SH
Sbjct: 187  --GGRAGPCFDQHGGQQSPGMGMMHSAS---------------AAAAGAPGSMDPLQNSH 229

Query: 637  -GQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVS 695
             G   S  +    Y + G+G G     G  G   G  S  G  G G+G   +    G+V+
Sbjct: 230  EGYPNSQCNHYPGYSRPGAGGG-----GGGGGGGGGGSGGGGGGGGAGAGGAGA--GAVA 282

Query: 696  GQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQH 755
              ++     +G G   GY    +G    S  R+ G   G        G++S   ++ G  
Sbjct: 283  AAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQG--GGMMMGPGGGGAASLSKAAAGSA 340

Query: 756  GSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCS------SSCGHYES 809
              G  + +G  +  SG+  + +++    S    S  G +   +S S      S      +
Sbjct: 341  AGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAA 400

Query: 810  GSGQASGFGQHESGSGQGY---SQHGSASGHFS----------SQGRHGSTSGQSSSSGQ 856
             +G A+G  Q  +G G G    +Q+ +AS  ++          S G  G T G+S  S  
Sbjct: 401  AAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPM 460

Query: 857  HDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSG-SGQSPSYGRHGSGSGR 915
                  +   YG   +          +  GS   PG  +   G  G++P     G+ +G 
Sbjct: 461  DPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTP-----GAMAGM 515

Query: 916  SSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGS 975
                 +     GQ    G+    GQ   Y+Q           +   S+S Q  + +Q  S
Sbjct: 516  QYPQQQMPPQYGQQGVSGY-CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMS 574

Query: 976  SSGSSSSYGQHGSGSRQSLGHGQ---HGSGSGQSPSPSRGRHGSGS------GQSSSYGP 1026
              G       +G+ S+  L  G+         Q   PS     SGS      G  ++   
Sbjct: 575  QEG-------YGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSS 627

Query: 1027 YRSGSGWSSSRG----PYES-----GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG 1077
              S SG +SS+G    P +S      S H S +    S S   S  G + S SG  S   
Sbjct: 628  AVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPAS 687

Query: 1078 QHGS-----TSGQSSSCGQHGASSGQSSSHGQHG-----SGSSQSSGYGRQGSGSGQSPG 1127
              GS       G  S    H A S QS    + G       + Q + YG Q +G   SP 
Sbjct: 688  IPGSQMPPQPPGSQSESSSHPALS-QSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSP- 745

Query: 1128 HGQRGSGSRQSPSYGRHG--SGSGRSSSSGQHG---SGLGESSGFGHHESSSG-QSSSYS 1181
                      SP    H   S   +S+SSG +G   S  G    +    + SG  S+SYS
Sbjct: 746  --------HPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYS 797

Query: 1182 QHGSGSGHSSGYGQHGSRSGQ----------SSRGERHGSSSGSSSHYGQHGSGSRQSSG 1231
              G G G S+    HG    Q           S G ++    G+ S       G  Q  G
Sbjct: 798  GPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGG 857

Query: 1232 HG---------RQGSGSGHSPSRGRHGSGLGHSSSH-GQHGSGSGRSSSRGPYESRSGHS 1281
             G         R+   +  +  +    S      S  G + SG   SSS  PY     +S
Sbjct: 858  PGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSS--PYSQPMNNS 915

Query: 1282 SVFGQHESGSGHSSAYSQHGS-----GSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSY 1336
            S    +     +S A +   S     G     S G+        +   +EG+   +S S 
Sbjct: 916  SSL-MNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSK 974

Query: 1337 -GHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 1395
              +   G SQ    G     S  SPS     S  G  S      S  GW  +     S S
Sbjct: 975  DSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDES---DSISSPGWPKTPSSPKSSS 1031

Query: 1396 GQSSG--------FGHH-ESSSWQSSGCTQHGSGSGHSSSYEQHGSRS------------ 1434
              ++G         G+  E   W     T         SS    G +             
Sbjct: 1032 STTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKE 1091

Query: 1435 ----GQSSRGERH---------GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR 1481
                 Q ++ ++          G+SS ++SS  +      Q L   +     G+ P P  
Sbjct: 1092 IGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQ---YIQYLFAFECKIERGEEPPPEV 1148

Query: 1482 GRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGL----GHRESRSGQSSGYGQ-H 1536
               G    Q     P  + SG  S +GP    S+ S+ +    G  +  +  S+ +GQ  
Sbjct: 1149 FSTGDTKKQPKLQPPSPANSG--SLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMT 1206

Query: 1537 GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 1596
                G SST   H   S  S S      S   ++ + Q   G S     GR      + P
Sbjct: 1207 PMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQ---GMSMPDVMGRMPYEPNKDP 1263

Query: 1597 GHGQRGSGSRQSP--SYGRHGSGS-----GRSSSSGQHGSGLGESSGFGHHESSSGQSSS 1649
              G R       P  + G+  + S      +S S      G+G+   F +  S   +   
Sbjct: 1264 FGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEP 1323

Query: 1650 YSQHGSGSGHSSGYGQHGSRS----GQSSRGERH-------GSSSRSSSRYGQHGSGSRQ 1698
            Y Q   G G  SG   +G        Q    +RH        +       Y    S  +Q
Sbjct: 1324 YGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQ 1383

Query: 1699 S--SGHGRQGSGSGQSPSRGRHG--------SGLGHSSSHG----QHGSGSGRSSSRGPY 1744
               + +G   SG  + P +G++          G G   +HG      G     SSS GP 
Sbjct: 1384 EMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQ 1443

Query: 1745 ES 1746
            ++
Sbjct: 1444 QN 1445



 Score =  103 bits (256), Expect = 3e-21
 Identities = 314/1414 (22%), Positives = 457/1414 (32%), Gaps = 223/1414 (15%)

Query: 1455 QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGS 1514
            QH   +  SLG G  G      P   + +HG     ++       G    S  G  +   
Sbjct: 73   QHPISNNNSLG-GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAP 131

Query: 1515 SHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQ 1574
                 +G       +  G G  G+     +  G  G  +        +G+++  S   G 
Sbjct: 132  PK---MGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGG 188

Query: 1575 HGS------GSSQSSGYGRQGSGSGQSPG------------HGQRGSGSRQSPSYGRHGS 1616
                     G  QS G G   S S  + G             G   S     P Y R G+
Sbjct: 189  RAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGA 248

Query: 1617 GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 1676
            G G     G  G   G   G G     +G  +  +   + +  + G G  G   G SS G
Sbjct: 249  GGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGG--GGGYGGSSAG 306

Query: 1677 ERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSG 1736
                SS R      Q G G     G G  G+ S    + G    G    +   QH SG+ 
Sbjct: 307  YGVLSSPR------QQGGGMMMGPGGG--GAASLSKAAAGSAAGGFQRFAGQNQHPSGAT 358

Query: 1737 RSSSR---GPYESRSGHSSVFGQHESGSG--------HSSAYSQHGSGSGHFCSQGQH-G 1784
             + ++    P      +   + ++ S S          S A +   +  G   + G   G
Sbjct: 359  PTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLG 418

Query: 1785 STSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGS-------------GSGQSPS 1831
               G          +  Q  SH     G+   +    QGS             G G +P 
Sbjct: 419  KDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPH 478

Query: 1832 RGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHES------SSWQSSGYT 1885
                 S      SYG  G         G  G   G  +G  + +            SGY 
Sbjct: 479  SQPQQSSPYPGGSYGPPGP---QRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYC 535

Query: 1886 QHGSGSGHSSSYE-QHGSRSGQ--SSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQ---H 1939
            Q G    +S   +  H     Q   S+ +Q        S  G +G+ S+  L  G+    
Sbjct: 536  QQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEG-YGTRSQPPLAPGKPNHE 594

Query: 1940 GSGSGQSPSPSRGRHGSGS------GQSSSYGPYGSGSGWSSSRG----PYES-----GS 1984
                 Q   PS     SGS      G  ++     S SG +SS+G    P +S      S
Sbjct: 595  DLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHAS 654

Query: 1985 GHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS-----ASGQSSSCGQHGASSGQS 2039
             H S +    S S   S  G + S SG  S     GS       G  S    H A S QS
Sbjct: 655  PHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALS-QS 713

Query: 2040 SSHGQHG-----SGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHG--SGSGRSS 2092
                + G       + Q + YG Q +G   SP           SP    H   S   +S+
Sbjct: 714  PMPQERGFMAGTQRNPQMAQYGPQQTGPSMSP---------HPSPGGQMHAGISSFQQSN 764

Query: 2093 SSGQHGPGLGESSGFGHHES----SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 2148
            SSG +GP + +    G++      S   S+SYS  G G G S+    HG    Q      
Sbjct: 765  SSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVP 824

Query: 2149 HG--SSSGSSSR--YGQHGSGSRQSSGHGRQGSGSGHSP------SRGRHGSG----SGH 2194
             G   S+G  +R   G   S +  S G  +QG G G  P       + +  +     +  
Sbjct: 825  LGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQG-GPGMGPPMPTVNRKAQEAAAAVMQAAA 883

Query: 2195 SSSHGQHGS-----GSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGS-----GS 2244
            +S+  + GS      SG  +S  PY     +SS    +     +S A +   S     G 
Sbjct: 884  NSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSL-MNTQAPPYSMAPAMVNSSAASVGL 942

Query: 2245 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGS-GSSQSSSYGQQGSGSGQSPSRG 2303
                S G+        +   +EG+   +S S   + S G SQ  + G     S  SPS  
Sbjct: 943  ADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSA 1002

Query: 2304 RHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSG--------FGHH-ESSSWQSSGY 2354
               S  G  S      S  GW  +     S S  ++G         G+  E   W     
Sbjct: 1003 SISSFHGDES---DSISSPGWPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYL 1059

Query: 2355 TQHGSGSGHSSSYEQHGSRS----------------GQSSRGERH---------GSSSGS 2389
            T         SS    G +                  Q ++ ++          G+SS +
Sbjct: 1060 TFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSA 1119

Query: 2390 SSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGP 2449
            +SS  +      Q L   +     G+ P P     G    Q     P  + SG  S +GP
Sbjct: 1120 ASSLKKQ---YIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSG--SLQGP 1174

Query: 2450 YESGSGHSSGL----GHRESRSGQSSGYGQ-HGSSSGHSSTHGQHGSTSGQSSSCGQHGA 2504
                S  S+ +    G  +  +  S+ +GQ      G SST   H   S  S S      
Sbjct: 1175 QTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRN 1234

Query: 2505 SSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSP--SYGRHGSGS---- 2558
            S   ++ + Q   G S     GR      + P  G R       P  + G+  + S    
Sbjct: 1235 SMTPNAPYQQ---GMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDM 1291

Query: 2559 -GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS----GQS 2613
              +S S      G+G+   F +  S   +   Y Q   G G  SG   +G        Q 
Sbjct: 1292 YNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQ 1351

Query: 2614 SRGERH-------GSSSGSSSHYGQHGSGSRQS--SGHGRQGSGSGQSPSRGRHG----- 2659
               +RH        +       Y    S  +Q   + +G   SG  + P +G++      
Sbjct: 1352 PNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSR 1411

Query: 2660 ---SGLGHSSSHG----QHGSGSGRSSSRGPYES 2686
                G G   +HG      G     SSS GP ++
Sbjct: 1412 ERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQN 1445



 Score =  100 bits (248), Expect = 3e-20
 Identities = 234/1026 (22%), Positives = 344/1026 (33%), Gaps = 128/1026 (12%)

Query: 233  QHKSSSGQSSGYSQHGSGS-GHSSGYGQHGSRSGQSSRGE----------RHRSSSGSSS 281
            QH  S+  S G +  G+   G      QHG     ++ G+          +      +  
Sbjct: 73   QHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPP 132

Query: 282  SYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESG 341
              G+   G  +  G G    G++Q P  V  G G   +     +  GS+   S G    G
Sbjct: 133  KMGEPAGGRYEHPGLG--ALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGG---PG 187

Query: 342  SGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSR-QSSSY 400
                  F QH        G    G G  HS+S          A+++G  GS    Q+S  
Sbjct: 188  GRAGPCFDQH-------GGQQSPGMGMMHSAS----------AAAAGAPGSMDPLQNSHE 230

Query: 401  GQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTG------FGRSSSSGP 454
            G   S   H  G  +  +G G   G G  G GSG     G  G G         ++++  
Sbjct: 231  GYPNSQCNHYPGYSRPGAGGGGGGGGGG-GGGSGGGGGGGGAGAGGAGAGAVAAAAAAAA 289

Query: 455  YVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSS 514
              +G G   G+G   +     S   Q G G     G G   S S  ++     GS+AG  
Sbjct: 290  AAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAA-----GSAAGGF 344

Query: 515  SSY---GQHGSGSRQSLGHSRHGSGSGQSPSPSR----GRHESGSRQSSSYGPHGYGSGR 567
              +    QH SG+  +L           SPSP      G +   S  S+   P      +
Sbjct: 345  QRFAGQNQHPSGATPTLNQLL------TSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398

Query: 568  SSSRGPYESGSGHSSGLGHQESRSGQ----SSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 623
            +++ G    G   ++G+G  +    Q    S  +      S  + + G  G T G+S   
Sbjct: 399  AAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGS 458

Query: 624  GQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSG 683
                    +   +G   +  SQ  +      GS   P   R+       +     G+ +G
Sbjct: 459  PMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTP----GAMAG 514

Query: 684  WSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHG 743
                        GQ    G+    GQ   YSQ           +   S+S Q  + +Q  
Sbjct: 515  MQYPQQQMPPQYGQQGVSGY-CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDM 573

Query: 744  SSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSS 803
            S  G       +G+ S      G+      +   + R  S    S S     +GT  + S
Sbjct: 574  SQEG-------YGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLS 626

Query: 804  CGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQ 863
                 S SG  S  G   + +   +S H  AS H SS     S S   S  G + S SG 
Sbjct: 627  SA--VSASGSTSSQGDQSNPAQSPFSPH--ASPHLSSIPGGPSPSPVGSPVGSNQSRSGP 682

Query: 864  SSSY-------------GQHESASHHASGRGRHGSGSGQSPGHGQRG--SGSGQSPSYGR 908
             S                Q ES+SH A           QSP   +RG  +G+ ++P   +
Sbjct: 683  ISPASIPGSQMPPQPPGSQSESSSHPA---------LSQSPMPQERGFMAGTQRNPQMAQ 733

Query: 909  HGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSS 968
            +G      S S     G    +G      S  S  Y    S  G   +Y +  + SG  S
Sbjct: 734  YGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPS 793

Query: 969  RS-EQHGSSSGSSSSYGQHGSGSRQSLGHGQHG----SGSGQSPSPSR--GRHGSGSGQS 1021
             S    G   G S++   HG G  Q  G    G    +G    P P        S  G S
Sbjct: 794  ASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMS 853

Query: 1022 SSYGPYRSGSGWSSSRGPYESGSG-HSSGLGHRESRSGQSSGYGQHG--SSSGHSSTHGQ 1078
               GP       + +R   E+ +    +     +SR G   G  Q G  +SS   S    
Sbjct: 854  QQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMN 913

Query: 1079 HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGR-----------QGSGSGQSPG 1127
            + S+   + +     A +  +SS    G     S G  +           +G+   +S  
Sbjct: 914  NSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKS 973

Query: 1128 HGQRGS-GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG 1186
                 S G  Q P+ G     S  S SS    S  G+ S      SS G   + S   S 
Sbjct: 974  KDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDES---DSISSPGWPKTPSSPKSS 1030

Query: 1187 SGHSSG 1192
            S  ++G
Sbjct: 1031 SSTTTG 1036



 Score = 90.9 bits (224), Expect = 2e-17
 Identities = 249/1097 (22%), Positives = 362/1097 (32%), Gaps = 194/1097 (17%)

Query: 1516 HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG----STSGQSSSCGQHGASSGQSSS 1571
            H+  L H  +   Q + + Q            Q      S +      G      G    
Sbjct: 38   HAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDME 97

Query: 1572 HGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGL 1631
              QHG     ++G      G    PG           P   + G         G+   G 
Sbjct: 98   QPQHGGAKDSAAG------GQADPPG----------PPLLSKPGDEDDAPPKMGEPAGGR 141

Query: 1632 GESSGFGHHESSSGQSSSYSQHGSGSG------HSSGYGQHGSRSGQSSRGERHGSSSRS 1685
             E  G G   +   Q    +  G G G       ++ YG     SG        G   R+
Sbjct: 142  YEHPGLG---ALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG--------GPGGRA 190

Query: 1686 SSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYE 1745
               + QHG                 QSP     G G+ HS+S     + +G   S  P +
Sbjct: 191  GPCFDQHGGQ---------------QSP-----GMGMMHSAS----AAAAGAPGSMDPLQ 226

Query: 1746 SRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 1805
            +     S  G   S   H   YS+ G+G G     G  G + G        G   G + +
Sbjct: 227  N-----SHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGG--------GGGGGGAGA 273

Query: 1806 HGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 1865
             G      + +++     +G G     G   +G G  SS  Q G G       G  G+ S
Sbjct: 274  GGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGG--GAAS 331

Query: 1866 GQSSGFGHHESSSWQSSGYTQHGSGS----------------GHSSSYEQHGSRSGQS-- 1907
               +  G       + +G  QH SG+                 +  SY ++ S S     
Sbjct: 332  LSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPP 391

Query: 1908 -SRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGP 1966
             S+ +   +++G+++   Q  +G    LG       +  SP+ +  +  S    S     
Sbjct: 392  PSQPQSQAAAAGAAAGGQQAAAG--MGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPG 449

Query: 1967 YGSGSGWSSSRGPYESGSGHSSGLGHR-ESRSGQSSGY--GQHGSSSGHSSTHGQHGSAS 2023
               G    S   P         G+G    S+  QSS Y  G +G         G  G   
Sbjct: 450  PTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTP 509

Query: 2024 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQS---------------PGH 2068
            G  +  G           +GQ G      SGY +QG     S               P  
Sbjct: 510  G--AMAGMQYPQQQMPPQYGQQGV-----SGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQ 562

Query: 2069 GQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSG 2128
             Q+    +Q  S   +G+ S    + G+  P   + +       SS    S S     +G
Sbjct: 563  SQQRYQPQQDMSQEGYGTRSQPPLAPGK--PNHEDLNLIQQERPSSLPDLSGSIDDLPTG 620

Query: 2129 HSSGYGQHGSRSGQ-SSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGR 2187
              +      S SG  SS+G++   S+ + S +  H S    S   G   S  G SP  G 
Sbjct: 621  TEATLSSAVSASGSTSSQGDQ---SNPAQSPFSPHASPHLSSIPGGPSPSPVG-SPV-GS 675

Query: 2188 HGSGSGHSSSHGQHGS-------GSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQH 2240
            + S SG  S     GS       GS   SS  P  S+S      G   +G+  +   +Q+
Sbjct: 676  NQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG-FMAGTQRNPQMAQY 734

Query: 2241 GSGSGHFCSQGQHGSTSGQS----STFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS 2296
            G       S   H S  GQ     S+F Q  SS          G+   Q S YG QG+ S
Sbjct: 735  GPQQTG-PSMSPHPSPGGQMHAGISSFQQSNSS----------GTYGPQMSQYGPQGNYS 783

Query: 2297 GQSPSRGRHGSGSG-HSSSYGQHGSGSGWSSSSGRHGSGSGQSSG---FGHHESSSWQSS 2352
                   R  + SG  S+SY   G G G S+++  HG G  Q  G    G   S+  Q+ 
Sbjct: 784  -------RPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR 836

Query: 2353 GYTQHGSGSGHSS--SYEQHGSRSG--QSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQ 2408
             +  + S    SS    +Q G   G    +   +   ++ +      + + SRQ    G 
Sbjct: 837  PFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGM 896

Query: 2409 HGSGSGQSPSP-SRGRHGSGSGQSSSYSPY----------GSGSGWSSSRGPYES----- 2452
            + SG   S SP S+  + S S  ++   PY           +  G +    P ES     
Sbjct: 897  NQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLP 956

Query: 2453 --GSGHSSGLGHRESRSGQSSGYGQHGSSS----GHSSTHGQHGSTSGQSSSCGQHGASS 2506
                G   G    ES+S  S  Y   G S     G+         +S   SS   HG  S
Sbjct: 957  LKADGKEEGTPQPESKSKDS--YSSQGISQPPTPGNLPVPSPMSPSSASISSF--HGDES 1012

Query: 2507 GQSSSHGQHGSGSSQSS 2523
               SS G   + SS  S
Sbjct: 1013 DSISSPGWPKTPSSPKS 1029



 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 267/1275 (20%), Positives = 402/1275 (31%), Gaps = 205/1275 (16%)

Query: 169  HNSYSGQSSSYGEQN--SDSHQSSGRGQCGSGSGQS-PNYGQHGSGSGQSSSNDTHGSGS 225
            H++ +  + + G  +   +SH+     QC    G S P  G  G G G        G G 
Sbjct: 209  HSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGG 268

Query: 226  GQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ 285
            G +        +   ++  +   +G G   GYG  GS +G        +   G     G 
Sbjct: 269  GGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYG--GSSAGYGVLSSPRQQGGGMMMGPGG 326

Query: 286  HGSGSRQSLGHGRQGSGSRQSPSHVRHGSGS----------------GHSSSHGQHGSGS 329
             G+ S      G    G ++     +H SG+                 +  S+ ++ S S
Sbjct: 327  GGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPS 386

Query: 330  ----------SYSYSRGHYESGSGQTSGFGQHESGSGQ----SSGYSKHGSGSGHSSSQG 375
                      S + + G    G    +G G  +    Q    S  ++     S  + S G
Sbjct: 387  APPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPG 446

Query: 376  QHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGS--------------G 421
              G T G++  S       ++   YG   +          +  GS              G
Sbjct: 447  TPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQG 506

Query: 422  QSPG--HGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVS----------GSGYSSGFGHHE 469
            ++PG   G +       P  GQ G          PY S           + Y        
Sbjct: 507  RTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQR 566

Query: 470  SSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLG 529
               +       +G+ S      G+         + ER  S    S S     +G+  +L 
Sbjct: 567  YQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLS 626

Query: 530  HSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQES 589
             +   SGS  S      + +  +   S + PH      S   GP  S  G  S +G  +S
Sbjct: 627  SAVSASGSTSS------QGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVG--SPVGSNQS 678

Query: 590  RSGQSSGYGQHGSS-----SGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSS 644
            RSG  S     GS       G  S    H + S QS    + G  +G           + 
Sbjct: 679  RSGPISPASIPGSQMPPQPPGSQSESSSHPALS-QSPMPQERGFMAGTQR--------NP 729

Query: 645  QSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWS---SSNGPHGSVSGQSSGF 701
            Q ++YG Q +G   SP     G      SS+ Q  S   +    S  GP G+ S   +  
Sbjct: 730  QMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYS 789

Query: 702  GHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHG--SSSGLSSS--YGQHGS 757
            G  S S     YS  G G   S+  + HG    Q   +   G   S+G+ +    G   S
Sbjct: 790  GVPSAS-----YSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSS 844

Query: 758  GSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGF 817
             +  S G  +QG G G  P        +  +++     +  S  S  G +          
Sbjct: 845  MTPSSPGMSQQG-GPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFP--------- 894

Query: 818  GQHESG---SGQGYSQ-HGSASGHFSSQGRHGS-----TSGQSSSSGQHDSSSGQSSSYG 868
            G ++SG   S   YSQ   ++S   ++Q    S      +  ++S G  D  S   S   
Sbjct: 895  GMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLP 954

Query: 869  QHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGR----HG- 923
                A     G  +  S S  S        G  Q P+ G     S  S SS      HG 
Sbjct: 955  LPLKADGKEEGTPQPESKSKDS----YSSQGISQPPTPGNLPVPSPMSPSSASISSFHGD 1010

Query: 924  -SGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR----SEQHGSSSG 978
             S S  S G+    SS +SS  T  G              R     R     E+ GS   
Sbjct: 1011 ESDSISSPGWPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVS 1070

Query: 979  SSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH-------GSGSGQSSS----YGPY 1027
            S  + G+      +     +   G  Q     + R        G+ S  +SS    Y  Y
Sbjct: 1071 SLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQY 1130

Query: 1028 RSGSGWSSSRGPYESGSGHSSGLGHRE--------SRSGQSSGYGQHGSSSGHS------ 1073
                     RG        S+G   ++        + SG   G     S+  +S      
Sbjct: 1131 LFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPG 1190

Query: 1074 ---------STHGQ-HGSTSGQSSSCGQHGASSGQSSS----------HGQHGSGSSQSS 1113
                     + HGQ      G+SS+   H   S  S S          +  +  G S   
Sbjct: 1191 DLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPD 1250

Query: 1114 GYGRQGSGSGQSPGHGQRGSGSRQSP--SYGRHGSGS-----GRSSSSGQHGSGLGESSG 1166
              GR      + P  G R       P  + G+  + S      +S S      G+G+   
Sbjct: 1251 VMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQ 1310

Query: 1167 FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS----GQSSRGERH-------GSSSGS 1215
            F +  S   +   Y Q   G G  SG   +G        Q    +RH        +    
Sbjct: 1311 FPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHE 1370

Query: 1216 SSHYGQHGSGSRQS--SGHGRQGSGSGHSPSRGRHG--------SGLGHSSSHG----QH 1261
               Y    S  +Q   + +G   SG    P +G++          G G   +HG      
Sbjct: 1371 GDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMM 1430

Query: 1262 GSGSGRSSSRGPYES 1276
            G     SSS GP ++
Sbjct: 1431 GGPLQSSSSEGPQQN 1445



 Score = 86.7 bits (213), Expect = 3e-16
 Identities = 207/912 (22%), Positives = 298/912 (32%), Gaps = 125/912 (13%)

Query: 1887 HGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQS 1946
            H   + H   +     +  Q  + +Q            QH   +  SLG G  G      
Sbjct: 35   HHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLG-GAGGGAPQPG 93

Query: 1947 PSPSRGRHG-----SGSGQSSSYGPY-----GSGSGWSSSRGPYESGSGHSSGLGHRESR 1996
            P   + +HG     +  GQ+   GP      G         G    G     GLG   ++
Sbjct: 94   PDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQ 153

Query: 1997 SGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCG--------QHGASSGQSSSHGQHGSG 2048
                +  G  G  +     +  +GSA+  S   G        QHG    QS   G   S 
Sbjct: 154  QPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQ--QSPGMGMMHSA 211

Query: 2049 SSQSSGYGRQGSGSGQSPGH-GQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGF 2107
            S+ ++G    GS       H G   S     P Y R G+G G     G  G   G   G 
Sbjct: 212  SAAAAG--APGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG 269

Query: 2108 GHHESSSGQ-----SSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQH 2162
            G     +G      +++ +   +G G   GYG  GS +G            G     G  
Sbjct: 270  GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYG--GSSAGYGVLSSPRQQGGGMMMGPGGG 327

Query: 2163 GSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHS- 2221
            G+ S   +  G    G      + +H SG+  + +           S  G Y   S  S 
Sbjct: 328  GAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSA 387

Query: 2222 -----SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSH 2276
                 S      + +G ++   Q  +G G     G   + +  +    Q+ S    S   
Sbjct: 388  PPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGT 447

Query: 2277 GQHGSGSSQSSSYGQ------QGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGR 2330
                 G SQ S          Q  G G +P      S      SYG  G         G 
Sbjct: 448  PGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQR---YPIGI 504

Query: 2331 HGSGSGQSSGFGHHESSSWQS------SGYTQHGSGSGHSS---------------SYEQ 2369
             G   G  +G  + +            SGY Q G    +S                S  Q
Sbjct: 505  QGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQ 564

Query: 2370 HGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSG 2429
               +  Q    E +G+ S    + G+        +   +  S    S S      G+ + 
Sbjct: 565  QRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEAT 624

Query: 2430 QSSSYSPYGSGSGWSSSRGPYES-----GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 2484
             SS+ S  GS S       P +S      S H S +    S S   S  G + S SG  S
Sbjct: 625  LSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPIS 684

Query: 2485 THGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG-- 2542
                 GS         Q   S  +SSSH                     QSP   +RG  
Sbjct: 685  PASIPGSQMPP-----QPPGSQSESSSH-----------------PALSQSPMPQERGFM 722

Query: 2543 SGSRQSPS---YGRHGSGSGRS---SSSGQHGSGL-----GESSG-FGHHESSSGQSSSY 2590
            +G++++P    YG   +G   S   S  GQ  +G+       SSG +G   S  G   +Y
Sbjct: 723  AGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNY 782

Query: 2591 SQHGSGSG-HSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSG------HG 2643
            S+  + SG  S+ Y   G   G S+  + HG   G S   G    G   S+G       G
Sbjct: 783  SRPPAYSGVPSASYSGPGPGMGISANNQMHG--QGPSQPCGAVPLGRMPSAGMQNRPFPG 840

Query: 2644 RQGSGSGQSPSRGRHGS-GLGHS----SSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHE 2698
               S +  SP   + G  G+G      +   Q  + +   ++    +SR G  S  G ++
Sbjct: 841  NMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQG--SFPGMNQ 898

Query: 2699 SG-SGHSSAYSQ 2709
            SG    SS YSQ
Sbjct: 899  SGLMASSSPYSQ 910



 Score = 84.0 bits (206), Expect = 2e-15
 Identities = 185/854 (21%), Positives = 275/854 (32%), Gaps = 111/854 (12%)

Query: 1999 QSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 2058
            Q   +  H     H + H  H  A  Q  +  Q      Q     Q       S+     
Sbjct: 24   QQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLG 83

Query: 2059 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH---GPGLGESSGFGHHESSSG 2115
            G+G G +P  G       + P +G    G+  S++ GQ    GP L    G         
Sbjct: 84   GAGGG-APQPGP----DMEQPQHG----GAKDSAAGGQADPPGPPLLSKPG-----DEDD 129

Query: 2116 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQ 2175
                  +   G     G G  G++    +     G  +        +GS +  S G G +
Sbjct: 130  APPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGR 189

Query: 2176 GSGSGHSPSRGRHGS--GSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 2233
                   P   +HG     G    H    + +G   S  P ++     S  G   S   H
Sbjct: 190  AG-----PCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQN-----SHEGYPNSQCNH 239

Query: 2234 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQG 2293
               YS+ G+G G     G  G + G        G   G + + G      + +++     
Sbjct: 240  YPGYSRPGAGGGGGGGGGGGGGSGG--------GGGGGGAGAGGAGAGAVAAAAAAAAAA 291

Query: 2294 SGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 2353
            +G G     G   +G G  SS  Q G G       G  G+ S   +  G       + +G
Sbjct: 292  AGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGG--GAASLSKAAAGSAAGGFQRFAG 349

Query: 2354 YTQHGSGS----------------GHSSSYEQHGSRSGQS---SRGERHGSSSGSSSSYG 2394
              QH SG+                 +  SY ++ S S      S+ +   +++G+++   
Sbjct: 350  QNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ 409

Query: 2395 QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGS 2454
            Q  +G    LG       +  SP+ +  +  S    S        G    S   P     
Sbjct: 410  QAAAG--MGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467

Query: 2455 GHSSGLGHR-ESRSGQSSGY--GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSS 2511
                G+G    S+  QSS Y  G +G         G  G T G  +  G           
Sbjct: 468  PQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPG--AMAGMQYPQQQMPPQ 525

Query: 2512 HGQHGSGSSQSSGYGRQGSGSGQS---------------PGHGQRGSGSRQSPSYGRHGS 2556
            +GQ G      SGY +QG     S               P   Q+    +Q  S   +G+
Sbjct: 526  YGQQGV-----SGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGT 580

Query: 2557 GSGRSSSSG------------QHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYG 2604
             S    + G            +  S L + SG    +  +G  ++ S   S SG +S  G
Sbjct: 581  RSQPPLAPGKPNHEDLNLIQQERPSSLPDLSG-SIDDLPTGTEATLSSAVSASGSTSSQG 639

Query: 2605 QHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGH 2664
               + +   S    H S   SS   G   S S   S  G   S SG        GS +  
Sbjct: 640  DQSNPA--QSPFSPHASPHLSSIPGGP--SPSPVGSPVGSNQSRSGPISPASIPGSQMPP 695

Query: 2665 SSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHG 2724
                 Q  S S  + S+ P     G  +       G+  +   +Q+G       S   H 
Sbjct: 696  QPPGSQSESSSHPALSQSPMPQERGFMA-------GTQRNPQMAQYGPQQTG-PSMSPHP 747

Query: 2725 STSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSG-QSLSHGRHGSGSGQSS 2783
            S  GQ          +  S +YG + S       Y R  A SG  S S+   G G G S+
Sbjct: 748  SPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISA 807

Query: 2784 SYGQHGSGSGQSSG 2797
            +   HG G  Q  G
Sbjct: 808  NNQMHGQGPSQPCG 821



 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 209/897 (23%), Positives = 303/897 (33%), Gaps = 99/897 (11%)

Query: 179  YGEQNSDSHQSSGR-GQCGS--GSGQSPNYGQHGSGSGQSSS---------NDTHGSGSG 226
            YG     S    GR G C    G  QSP  G   S S  ++          N   G  + 
Sbjct: 176  YGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNS 235

Query: 227  QSSGFSQHKSSSGQSSGYSQHGSGSGHS-SGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ 285
            Q + +  + S  G   G    G G G S  G G  G+ +G +  G    +++ ++++ G 
Sbjct: 236  QCNHYPGY-SRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGG 294

Query: 286  HGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQT 345
             G G     G    G G   SP       G G     G  G+ S    + G    G  + 
Sbjct: 295  GGGG---GYGGSSAGYGVLSSPRQ----QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRF 347

Query: 346  SGFGQHESGSGQSSGY---SKHGSGSGHSSSQGQHGSTSGQASSSGQ-HGSSSRQSSSYG 401
            +G  QH SG+  +      S       +  S  ++ S S       Q    ++   ++ G
Sbjct: 348  AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407

Query: 402  QHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSS--GPYVSGS 459
              ++A+    G+   +  +  SP        S  + S G  G   GRS  S   P V   
Sbjct: 408  GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467

Query: 460  GYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHG-SRSGQSSRGERQGSSAGSS---- 514
                G G +  S    S     GS       +G  G  R     +G   G+ AG      
Sbjct: 468  PQLYGMGSNPHSQPQQSSPYPGGS-------YGPPGPQRYPIGIQGRTPGAMAGMQYPQQ 520

Query: 515  ---SSYGQHGSGSRQSLGHSRHGSGSGQSPS--------PSRGRHESGSRQSSSYGPHGY 563
                 YGQ G       G   + S   Q P         PS+ +     +Q  S    GY
Sbjct: 521  QMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMS--QEGY 578

Query: 564  GSGRSSSRGPYESGSGHSSGLG--HQESRSGQSSGYGQ-HGSSSGHSSTHGQHGSTSGQS 620
            G   + S+ P   G  +   L    QE  S      G      +G  +T     S SG +
Sbjct: 579  G---TRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGST 635

Query: 621  SSCGQHG--ATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFG-HSSSYGQ 677
            SS G     A S  S     H S           GS  G + SR    S      S    
Sbjct: 636  SSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPP 695

Query: 678  HGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSS 737
               GS   SS+ P  S S      G  +G+ ++   +Q+G   +  S    H S  GQ  
Sbjct: 696  QPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPS-MSPHPSPGGQMH 754

Query: 738  RSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSG-HSPSRVRHGSSSGHSSSHGQHGS 796
                    S  S +YG   S       + R  + SG  S S    G   G S+++  HG 
Sbjct: 755  AGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQ 814

Query: 797  GTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQ 856
            G   S  CG    G   ++G  Q+    G   S   S+ G  S QG  G      +    
Sbjct: 815  GP--SQPCGAVPLGRMPSAGM-QNRPFPGNMSSMTPSSPG-MSQQGGPGMGPPMPTV--- 867

Query: 857  HDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSP-SYGRHGSGSGR 915
              +   Q ++    ++A++ A  R       G  PG  Q G  +  SP S   + S S  
Sbjct: 868  --NRKAQEAAAAVMQAAANSAQSR------QGSFPGMNQSGLMASSSPYSQPMNNSSSLM 919

Query: 916  SSSSGRHG------SGSGQSSGFGHKSSSGQS-------SGYTQHGSGSGHSSSYEQHGS 962
            ++ +  +       + S  S G     S G+S       +   + G+    S S + + S
Sbjct: 920  NTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSS 979

Query: 963  RS-------GQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG 1012
            +        G          SS S SS+    S S  S G  +  S    S S + G
Sbjct: 980  QGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSSPKSSSSTTTG 1036



 Score = 79.7 bits (195), Expect = 4e-14
 Identities = 169/744 (22%), Positives = 246/744 (33%), Gaps = 105/744 (14%)

Query: 2135 QHGSRSGQSSRGE----------RHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPS 2184
            QHG     ++ G+          + G    +  + G+   G  +  G G  G+       
Sbjct: 100  QHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAV 159

Query: 2185 RGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS 2244
             G  G  +     +  +GS +  S   G    R+G    F QH    G  S     G G 
Sbjct: 160  PGGGGGPAAVPEFNNYYGSAAPASGGPG---GRAG--PCFDQH---GGQQSP----GMGM 207

Query: 2245 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGR 2304
             H  S    G+          + S  G  +S   H  G S+  + G  G G G     G 
Sbjct: 208  MHSASAAAAGAPGSMDPL---QNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGG 264

Query: 2305 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHS 2364
             G G G     G  G+G+G  +++    + +    G G          GY    +G G  
Sbjct: 265  GGGGGGA----GAGGAGAGAVAAAAAAAAAAAGGGGGG----------GYGGSSAGYGVL 310

Query: 2365 SSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ-------SP 2417
            SS  Q G        G   G++S S ++ G    G ++  G  QH SG+         SP
Sbjct: 311  SSPRQQGGGMMMGPGGG--GAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSP 368

Query: 2418 SPSRGRHGSGSGQSSSYS----PYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQ---- 2469
            SP    +G    + SS S    P       +++ G    G   ++G+G  +    Q    
Sbjct: 369  SPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAA 428

Query: 2470 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSC---------------GQHGASSGQSSSH-- 2512
            S  +      S  + + G  G T G+S                  G +  S  Q SS   
Sbjct: 429  SPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYP 488

Query: 2513 -GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHG------SGSGRSSSSG 2565
             G +G    Q    G QG   G   G   +    +  P YG+ G       G     S  
Sbjct: 489  GGSYGPPGPQRYPIGIQGRTPGAMAG--MQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQ 546

Query: 2566 QHGSGLGESSGFGHHESSSG----QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGS 2621
                 L   + +   +S       Q  S   +G+ S      G+         + ER  S
Sbjct: 547  PQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSS 606

Query: 2622 SSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSR 2681
                S       +G+  +       SGS  S     + +     S    H S    S   
Sbjct: 607  LPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPA----QSPFSPHASPHLSSIPG 662

Query: 2682 GPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS----GQSSTFDQEG 2737
            GP  S +G  S  G ++S SG  S  S  GS         Q  S+S     QS    + G
Sbjct: 663  GPSPSPVG--SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG 720

Query: 2738 SSTG-----QSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGS 2792
               G     Q + YG + +G S S     H +  GQ  +       S  S +YG   S  
Sbjct: 721  FMAGTQRNPQMAQYGPQQTGPSMSP----HPSPGGQMHAGISSFQQSNSSGTYGPQMSQY 776

Query: 2793 GQSSGYSQHGSGSGQDGYSYCKGG 2816
            G    YS+  + SG    SY   G
Sbjct: 777  GPQGNYSRPPAYSGVPSASYSGPG 800



 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 101/461 (21%), Positives = 151/461 (32%), Gaps = 34/461 (7%)

Query: 2219 GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQ 2278
            G +     H+    H  A+  H     H      H +   Q + F Q+     Q     Q
Sbjct: 15   GEAPAAPPHQQHHHHHHAHHHHH----HAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQ 70

Query: 2279 HGSGS-SQSSSYGQQGSGSGQ-SPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 2336
                  S ++S G  G G+ Q  P   +   G    S+ G      G    S + G    
Sbjct: 71   QQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS-KPGDEDD 129

Query: 2337 QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQH 2396
                 G      ++  G    G+     +     G  +        +GS++ +S      
Sbjct: 130  APPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG----- 184

Query: 2397 GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGH 2456
            G G R      QHG   GQ  SP  G   S S  ++  +P       +S  G   S   H
Sbjct: 185  GPGGRAGPCFDQHG---GQQ-SPGMGMMHSASAAAAG-APGSMDPLQNSHEGYPNSQCNH 239

Query: 2457 SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHG 2516
              G     +  G   G G  G S G     G     +G  +      A++  +   G  G
Sbjct: 240  YPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGG 299

Query: 2517 SGSSQSSGYG------RQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSG 2570
             G S S+GYG      +QG G    PG G  G+ S    + G    G  R +   QH SG
Sbjct: 300  YGGS-SAGYGVLSSPRQQGGGMMMGPGGG--GAASLSKAAAGSAAGGFQRFAGQNQHPSG 356

Query: 2571 LGE------SSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSG 2624
                     +S      S  G    YS   +     S      + +G ++ G++  +  G
Sbjct: 357  ATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMG 416

Query: 2625 SSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHS 2665
                 G   + +  +    +Q S    SP  G  G  +G S
Sbjct: 417  LGKDMGAQYAAASPAWAAAQQRSHPAMSP--GTPGPTMGRS 455



 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 208/921 (22%), Positives = 300/921 (32%), Gaps = 141/921 (15%)

Query: 248  GSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGS------ 301
            G+ +  SS     GS S Q  +      S+ + S +  H S    S+  G   S      
Sbjct: 620  GTEATLSSAVSASGSTSSQGDQ------SNPAQSPFSPHASPHLSSIPGGPSPSPVGSPV 673

Query: 302  GSRQSPSH-VRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSG 360
            GS QS S  +   S  G        GS S  S      +S   Q  GF      + Q + 
Sbjct: 674  GSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQ 733

Query: 361  YSKHGSG---SGHSSSQGQ-HGSTSG--QASSSGQHGSSSRQSSSYGQHESASRHSSGRG 414
            Y    +G   S H S  GQ H   S   Q++SSG +G    Q S YG   + SR  +  G
Sbjct: 734  YGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGP---QMSQYGPQGNYSRPPAYSG 790

Query: 415  QHSSG-SGQSPG---------HGQRGSGS------GQSPSSGQHGTGF-GRSSSSGPYVS 457
              S+  SG  PG         HGQ  S        G+ PS+G     F G  SS  P   
Sbjct: 791  VPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSP 850

Query: 458  GSGYSSGFGH-------HESSSEHSSGYTQHGSGSGHSS-----GHGQHGSRSGQSSRGE 505
            G     G G        +  + E ++   Q  + S  S      G  Q G  +  S   +
Sbjct: 851  GMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQ 910

Query: 506  RQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGR---------HESGSRQSS 556
               +S+   ++     S +   +  S    G     SP   +          E G+ Q  
Sbjct: 911  PMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPE 970

Query: 557  SYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGST 616
            S     Y S +  S+ P        S +    S +  SS +G    S   SS       +
Sbjct: 971  SKSKDSYSS-QGISQPPTPGNLPVPSPMS--PSSASISSFHGDESDSI--SSPGWPKTPS 1025

Query: 617  SGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRY----GQQGSGSGQSPSRGRHGSDFGHS 672
            S +SSS    G    +    G          RY     ++GS     P+ G+   D    
Sbjct: 1026 SPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRL 1085

Query: 673  SSYGQHGSGSGWSSSNGPHGSVSGQSS-GFGHKSGSGQSSGYSQH--------GSGSSHS 723
                +   G    + N     ++   + G    + S     Y Q+          G    
Sbjct: 1086 YVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPP 1145

Query: 724  SGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGH----SPSRV 779
                  G    Q        ++SG        G  + QS+G        G     +P+  
Sbjct: 1146 PEVFSTGDTKKQPKLQPPSPANSG-----SLQGPQTPQSTGSNSMAEVPGDLKPPTPAST 1200

Query: 780  RHGSSS----GHSSSHGQHGSGTSCSSSC----------GHYESGSGQASGFGQHESGSG 825
             HG  +    G SS+   H   +  S S             Y+ G       G+      
Sbjct: 1201 PHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPN 1260

Query: 826  Q----GYSQHGSASGHFSSQGRHGSTS-----GQSSSSGQHDSSSGQSSS--YGQHESAS 874
            +    G  +   +S  F +QG+  ++S      QS S    +   GQ     YG      
Sbjct: 1261 KDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRR 1320

Query: 875  HHASGRGRHGSG--SGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSG- 931
            H   G+   G G  SGQ P  G +     Q P+Y RH          G +G  + +  G 
Sbjct: 1321 HEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRH--------MDGMYGPPAKRHEGD 1372

Query: 932  -FGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGS 990
             +  + SS Q   Y Q+G            GS SG   R  Q G      S     G G 
Sbjct: 1373 MYNMQYSSQQQEMYNQYG------------GSYSGPDRRPIQ-GQYPYPYSRERMQGPGQ 1419

Query: 991  RQSLG-HGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPY--RSGSGWSSSRGPYESGSGHS 1047
             Q+ G   Q   G  QS S    +    + ++    PY  R G G  +   PY  G   +
Sbjct: 1420 IQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPY-PGMNRT 1478

Query: 1048 SGLGHRESRSGQSSGYGQHGS 1068
              +   + R    S +  H S
Sbjct: 1479 DDMMVPDQRINHESQWPSHVS 1499



 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 84/399 (21%), Positives = 128/399 (32%), Gaps = 67/399 (16%)

Query: 2469 QSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 2528
            Q   +  H     H + H  H     Q  +  Q      Q     Q       S+     
Sbjct: 24   QQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLG 83

Query: 2529 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH---GSGLGESSGFGHHESSSG 2585
            G+G G +P  G       + P +G    G+  S++ GQ    G  L    G         
Sbjct: 84   GAGGG-APQPGP----DMEQPQHG----GAKDSAAGGQADPPGPPLLSKPG-----DEDD 129

Query: 2586 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHG-R 2644
                  +   G     G G  G++    +     G  +        +GS +  S G G R
Sbjct: 130  APPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGR 189

Query: 2645 QGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHS 2704
             G    Q   +   G G+ HS+S     + +G   S  P ++     S  G   S   H 
Sbjct: 190  AGPCFDQHGGQQSPGMGMMHSAS----AAAAGAPGSMDPLQN-----SHEGYPNSQCNHY 240

Query: 2705 SAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGA 2764
              YS+ G+G G        G   G        G  +G     G  G+G + +       A
Sbjct: 241  PGYSRPGAGGG--------GGGGGGG------GGGSGGGGGGGGAGAGGAGAGAVAAAAA 286

Query: 2765 GSGQSLSHGRHGSGSGQSSSYG------------QHGSGSGQSSGYSQHGSGSGQDGYSY 2812
             +  +   G  G   G S+ YG              G G G ++  S+  +GS   G+  
Sbjct: 287  AAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQR 346

Query: 2813 CKGGSNHDGGSS--------------GSYFLSFPSSTSP 2837
              G + H  G++               SY  S+P  +SP
Sbjct: 347  FAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSP 385



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 81/328 (24%), Positives = 110/328 (33%), Gaps = 59/328 (17%)

Query: 2390 SSSYGQHGSGSRQSLGHGQHGSGSG--QSPSPSRGRHGSGS----GQSSSYSPYGSGSGW 2443
            ++S    G  + QS G        G  + P+P+   HG  +    G+SS+ S +   S  
Sbjct: 1166 ANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDV 1225

Query: 2444 SSS----------RGPYESGSGHSSGLGHR--ESRSGQSSGYGQHGSSSGHSSTHGQHGS 2491
            S S            PY+ G      +G    E       G  +   SS    T GQ  +
Sbjct: 1226 SDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPN 1285

Query: 2492 TS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ----GSGSGQSPGHGQRG 2542
            +S      QS S        GQ        S   +   YG+Q    G  SGQ P  G + 
Sbjct: 1286 SSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQP 1345

Query: 2543 SGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 2602
                Q P+Y RH  G     +    G          + + SS Q   Y+Q+G        
Sbjct: 1346 GLYPQQPNYKRHMDGMYGPPAKRHEGD-------MYNMQYSSQQQEMYNQYG-------- 1390

Query: 2603 YGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL 2662
                GS SG   R    G      S     G G  Q+ G   Q             G  L
Sbjct: 1391 ----GSYSGPDRR-PIQGQYPYPYSRERMQGPGQIQTHGIPPQ-----------MMGGPL 1434

Query: 2663 GHSSSHG-QHGSGSGRSSSRGPYESRLG 2689
              SSS G Q    + R+    PY++R G
Sbjct: 1435 QSSSSEGPQQNMWAARNDMPYPYQNRQG 1462


>gi|7706635 cornulin [Homo sapiens]
          Length = 495

 Score =  118 bits (296), Expect = 7e-26
 Identities = 129/533 (24%), Positives = 203/533 (38%), Gaps = 57/533 (10%)

Query: 1   MPKLLQGVITVIDVFYQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQS 60
           MP+LLQ +  +I+ F +YA   G    L + ELK LLE EF  ++  P+DP TVD +L+ 
Sbjct: 1   MPQLLQNINGIIEAFRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRL 60

Query: 61  LDRDHNKKVDFTEYLLMIFKLVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEEN 120
           LD DH   V+F E+L+++FK+ QA  K + +      GS+     H    ++    +   
Sbjct: 61  LDEDHTGTVEFKEFLVLVFKVAQACFKTLSESAEGACGSQESGSLHSGASQELGEGQRSG 120

Query: 121 KRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYG 180
                +     +    +    +  RG  +PG ++            GQ    S   SSY 
Sbjct: 121 TEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQT-----------QGQATG-SAWVSSYD 168

Query: 181 EQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQ 240
            Q     Q     Q    SGQ+    + G G  ++ + +       Q+      +     
Sbjct: 169 RQAESQSQERISPQI-QLSGQTEQTQKAGEGK-RNQTTEMRPERQPQT-----REQDRAH 221

Query: 241 SSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQG 300
            +G +  GSG+   +G  Q   +      G   + +  +++          Q+ G    G
Sbjct: 222 QTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATND---------QNRGTETHG 272

Query: 301 SGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSG 360
            G  Q+   V  G     + +H Q  + +    S     S S QT      ES +GQ+ G
Sbjct: 273 QGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQT-----QESTNGQNRG 327

Query: 361 YSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGS 420
              HG G   +S     G T  QA   G H  +  Q  S          S G  +    +
Sbjct: 328 TEIHGQGRSQTSQAVTGGHTQIQA---GSHTETVEQDRS-------QTVSHGGAREQGQT 377

Query: 421 GQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQ 480
              PG GQR      +P +G+   G G++         +G S+  G  E SS H      
Sbjct: 378 QTQPGSGQRWM-QVSNPEAGETVPG-GQAQ--------TGASTESGRQEWSSTHPRRCVT 427

Query: 481 HGSGSGHSSGHGQH----GSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLG 529
            G G    +  G+      SR     R ++       SS+ GQ  + S +  G
Sbjct: 428 EGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRG 480



 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 102/402 (25%), Positives = 146/402 (36%), Gaps = 37/402 (9%)

Query: 190 SGRGQCGSGSGQSPNYGQHGS-GSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHG 248
           S  G CGS    S + G     G GQ S  +   +G GQ    S H+ S   S G ++ G
Sbjct: 92  SAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPG 151

Query: 249 ---SGSGHSSGYGQHGSRSGQSSRGERHRSS---SGSSSSYGQHGSGSRQSLGHGRQGSG 302
               G    S +     R  +S   ER       SG +    + G G R      R    
Sbjct: 152 VQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQ 211

Query: 303 SRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYS 362
            +       H +G   + S  Q  +G++ +  +      +G+TS   Q E+ + Q+ G  
Sbjct: 212 PQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQ-TGRTSKQTQ-EATNDQNRGTE 269

Query: 363 KHGSG---------SGHSSSQ-GQHGSTSGQA---SSSGQHGSSSRQS--SSYGQHESAS 407
            HG G          GH+  Q G H  T  Q     SS Q GS+S Q+  S+ GQ+    
Sbjct: 270 THGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTE 329

Query: 408 RHSSGRGQHSSGSGQSPGHGQRGSGSG----QSPSSGQHGTGFGRSSSSGPYVSGSGYS- 462
            H  GR Q S     + GH Q  +GS     +   S     G  R         GSG   
Sbjct: 330 IHGQGRSQTS--QAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRW 387

Query: 463 SGFGHHESSSEHSSGYTQHGSG--SGHSSGHGQHGSRSGQSSRGERQGSSAGSS--SSYG 518
               + E+      G  Q G+   SG       H  R     +G+RQ +  G      + 
Sbjct: 388 MQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDDHS 447

Query: 519 QHGSGSRQSLG--HSRHGSGSGQSPSPSRGRHESGSRQSSSY 558
           +     R   G  H+   S  GQ  + S  +    +R+  SY
Sbjct: 448 RETVILRLDQGNLHTSVSSAQGQDAAQSEEKRGITARELYSY 489



 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 108/466 (23%), Positives = 157/466 (33%), Gaps = 101/466 (21%)

Query: 324 QHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGH-SSSQGQHGS--- 379
           +   G+  S   G   SG+ Q  G GQ        +G  +H  GS H  S QG  G    
Sbjct: 91  ESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRP 150

Query: 380 ---TSGQASSSGQHGSSSRQSSSYGQHE-SASRHSSGRGQHSSGSGQSPGHGQRGSGSGQ 435
              T GQA+ S    S  RQ+ S  Q   S     SG+ + +    Q  G G+R   +  
Sbjct: 151 GVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQT----QKAGEGKRNQTTEM 206

Query: 436 SPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHG 495
            P          R+  +G  V+GSG  +  G  ++  + SS  T                
Sbjct: 207 RPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQT---------------- 250

Query: 496 SRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQS 555
              G++S+  ++ ++               Q+ G   HG G  Q+     G H       
Sbjct: 251 ---GRTSKQTQEATND--------------QNRGTETHGQGRSQTSQAVTGGHAQIQA-- 291

Query: 556 SSYGPHGYGSGRSSSRGPYESGSGHSSG---LGHQESRSGQSSGYGQHGSSSGHSSTHGQ 612
                   G+   +     E  S H +G      QES +GQ+ G   HG     +S    
Sbjct: 292 --------GTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVT 343

Query: 613 HGSTSGQSSSCGQHGATSGQSSSHG-QHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGH 671
            G T  Q+   G H  T  Q  S    HG    Q           GQ+ +          
Sbjct: 344 GGHTQIQA---GSHTETVEQDRSQTVSHGGAREQ-----------GQTQT---------- 379

Query: 672 SSSYGQHGSGSGWSSSNGPHG--SVSGQSSGFGHKSGSGQSSGYSQH-------GSGSSH 722
                Q GSG  W   + P    +V G  +  G  + SG+    S H       G G   
Sbjct: 380 -----QPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQ 434

Query: 723 ----SSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSG 764
                  +    SR     R +Q    + +SS+ GQ  + S +  G
Sbjct: 435 PTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRG 480



 Score = 68.6 bits (166), Expect = 9e-11
 Identities = 103/414 (24%), Positives = 160/414 (38%), Gaps = 55/414 (13%)

Query: 1847 QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQ 1906
            +   G+  S  SG   SG+ Q  G G    +    +G  QH  GS H  S  Q GSR GQ
Sbjct: 91   ESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQS--QQGSR-GQ 147

Query: 1907 SSRGEQ-HGSSSGSS--SSYGQHGSGSRQS--------LGHGQHGSGSGQSP-------S 1948
            +  G Q  G ++GS+  SSY +      Q          G  +    +G+          
Sbjct: 148  NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207

Query: 1949 PSRGRHGSGSGQSSSYGPYGSGSGWSSSRG---PYESGSGHSSGLGHR---ESRSGQSSG 2002
            P R        ++   G   +GSG  +  G     E  S H +G   +   E+ + Q+ G
Sbjct: 208  PERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRG 267

Query: 2003 YGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS 2062
               HG     +S     G A  Q+ +  Q    + +  S  Q GS S+Q+     Q S +
Sbjct: 268  TETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQT-----QESTN 322

Query: 2063 GQSPG---HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSS 2119
            GQ+ G   HGQ  S + Q+ + G     +G  + + +      + S    H  +  Q  +
Sbjct: 323  GQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQ-----DRSQTVSHGGAREQGQT 377

Query: 2120 YSQHGSG----------SGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQS 2169
             +Q GSG          +G +   GQ  +++G S+   R   SS    R    G G RQ 
Sbjct: 378  QTQPGSGQRWMQVSNPEAGETVPGGQ--AQTGASTESGRQEWSSTHPRRCVTEGQGDRQP 435

Query: 2170 SGHGRQGSGSGHSPSRG--RHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHS 2221
            +  G +     HS      R   G+ H+S     G  + +S  +    +R  +S
Sbjct: 436  TVVGEEWV-DDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRGITARELYS 488



 Score = 65.5 bits (158), Expect = 7e-10
 Identities = 97/368 (26%), Positives = 132/368 (35%), Gaps = 34/368 (9%)

Query: 789  SSHGQHGSGTSCSSSCG-HYESGSGQASGF-------GQHESGSGQGYSQHGSASGHFSS 840
            S+ G  GS  S S   G   E G GQ SG        GQH  GS    SQ GS       
Sbjct: 92   SAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGS-----RG 146

Query: 841  QGRHG-STSGQSSSSGQHDSSSGQSSSYGQHE-SASHHASGRGRHGSGSGQSPGHGQRGS 898
            Q R G  T GQ++ S    S   Q+ S  Q   S     SG+    +   Q  G G+R  
Sbjct: 147  QNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQ----TEQTQKAGEGKRNQ 202

Query: 899  GSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYE 958
             +   P          R+  +G   +GSG  +  G   +  Q S +      +G +S   
Sbjct: 203  TTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQ-----TGRTSKQT 257

Query: 959  QHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS 1018
            Q  + + Q+  +E HG     +S     G    Q+  H Q  + + +  S  +    S  
Sbjct: 258  QEAT-NDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQ 316

Query: 1019 GQSSSYGPYRS----GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 1074
             Q S+ G  R     G G S +      G        H E+     S    HG +     
Sbjct: 317  TQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQ 376

Query: 1075 THGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSG 1134
            T  Q G  SGQ          +G++   GQ  +G+S  S  GRQ   S         G G
Sbjct: 377  TQTQPG--SGQ-RWMQVSNPEAGETVPGGQAQTGASTES--GRQEWSSTHPRRCVTEGQG 431

Query: 1135 SRQSPSYG 1142
             RQ    G
Sbjct: 432  DRQPTVVG 439



 Score = 65.1 bits (157), Expect = 1e-09
 Identities = 83/351 (23%), Positives = 134/351 (38%), Gaps = 39/351 (11%)

Query: 2111 ESSSGQSSSYSQHGSGSGHSSGYGQH-GSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQS 2169
            E + G   S S H SG+    G GQ  G+  G++ +G+ +    GSS R  Q GS  +  
Sbjct: 94   EGACGSQESGSLH-SGASQELGEGQRSGTEVGRAGKGQHY---EGSSHRQSQQGSRGQNR 149

Query: 2170 SGHGRQGSGSGHS--PSRGRHGSG------------SGHSSSHGQHGSGSGRSSSRGPYE 2215
             G   QG  +G +   S  R                SG +    + G G    ++    E
Sbjct: 150  PGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPE 209

Query: 2216 SRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 2275
             +         H++G   + + +Q  +G+     Q     T G++S   QE ++  Q+  
Sbjct: 210  RQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQT-GRTSKQTQEATND-QNRG 267

Query: 2276 HGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 2335
               HG G SQ+S     G    Q+ +  +  + +    S  Q GS S  +  S    +  
Sbjct: 268  TETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRG 327

Query: 2336 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQ 2395
             +  G G  ++S   + G+TQ  +GS H+ + EQ  S++        HG +     +  Q
Sbjct: 328  TEIHGQGRSQTSQAVTGGHTQIQAGS-HTETVEQDRSQT------VSHGGAREQGQTQTQ 380

Query: 2396 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSS 2446
             GSG R             Q  +P  G    G    +  S       WSS+
Sbjct: 381  PGSGQRWM-----------QVSNPEAGETVPGGQAQTGASTESGRQEWSST 420



 Score = 64.3 bits (155), Expect = 2e-09
 Identities = 100/422 (23%), Positives = 157/422 (37%), Gaps = 40/422 (9%)

Query: 1377 QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQ 1436
            +   G+  S  SG   SG+ Q  G G    +    +G  QH  GS H  S  Q GSR   
Sbjct: 91   ESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQS--QQGSRGQN 148

Query: 1437 SSRGERHGSSSGSS--SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY 1494
                +  G ++GS+  SSY +      Q     Q    SGQ+    +   G  + Q++  
Sbjct: 149  RPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQL-SGQTEQTQKAGEGKRN-QTTEM 206

Query: 1495 SPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSG 1554
             P          R P       +   G   + SG  +  G   +    SS   Q G TS 
Sbjct: 207  RP---------ERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSH--QTGRTSK 255

Query: 1555 QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 1614
            Q+       A++ Q+     HG G SQ+S     G    Q+  H Q  + + +  S  + 
Sbjct: 256  QTQE-----ATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQT 310

Query: 1615 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 1674
            GS S ++  S    +   E  G G  ++S   +  ++Q  +GS H+    Q  S++    
Sbjct: 311  GSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGS-HTETVEQDRSQT---- 365

Query: 1675 RGERHGSSSRSSSRYGQHGSGSR------QSSGHGRQG--SGSGQSPSRGRHGSGLGHSS 1726
                HG +        Q GSG R        +G    G  + +G S   GR      H  
Sbjct: 366  --VSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPR 423

Query: 1727 SHGQHGSGSGRSSSRG-PYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGS 1785
                 G G  + +  G  +       +V  + + G+ H+S  S  G  +    S+ + G 
Sbjct: 424  RCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQ--SEEKRGI 481

Query: 1786 TS 1787
            T+
Sbjct: 482  TA 483



 Score = 63.2 bits (152), Expect = 4e-09
 Identities = 109/442 (24%), Positives = 158/442 (35%), Gaps = 55/442 (12%)

Query: 1495 SPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGH-SSTHGQHGSTS 1553
            S    G+  S   G   SG+S   G G R       +G GQH   S H  S  G  G   
Sbjct: 90   SESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNR 149

Query: 1554 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG---SGQSPGHGQRGSGSRQSPS 1610
                + GQ   S+  SS   Q  S S +      Q SG     Q  G G+R   +   P 
Sbjct: 150  PGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPE 209

Query: 1611 YGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS 1670
                     R+  +G+  +G G  +  G  ++    SS        +G +S   Q  + +
Sbjct: 210  RQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQ------TGRTSKQTQEAT-N 262

Query: 1671 GQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQ 1730
             Q+   E HG     +S+    G    Q+  H        Q+P++      +   SSH Q
Sbjct: 263  DQNRGTETHGQGRSQTSQAVTGGHAQIQAGTH-------TQTPTQ-----TVEQDSSH-Q 309

Query: 1731 HGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQS 1790
             GS S ++      ES +G +   G    G G S   SQ  +G GH  +Q Q GS    +
Sbjct: 310  TGSTSTQTQ-----ESTNGQNR--GTEIHGQGRSQT-SQAVTG-GH--TQIQAGS---HT 355

Query: 1791 STFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSG----QSPSRGRHGSGSGHSSSYG 1846
             T +Q+ S T        HG    Q  +  Q GSG       +P  G    G    +   
Sbjct: 356  ETVEQDRSQT------VSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGAS 409

Query: 1847 QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSW-----QSSGYTQHGSGSGHSSSYEQHG 1901
                   WSS+  R     GQ           W     + +   +   G+ H+S     G
Sbjct: 410  TESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQG 469

Query: 1902 SRSGQSSRGEQHGSSSGSSSSY 1923
              + QS   E+ G ++    SY
Sbjct: 470  QDAAQSE--EKRGITARELYSY 489



 Score = 63.2 bits (152), Expect = 4e-09
 Identities = 95/419 (22%), Positives = 156/419 (37%), Gaps = 34/419 (8%)

Query: 2317 QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQ 2376
            +   G+  S  SG   SG+ Q  G G    +    +G  QH  GS H  S  Q GSR   
Sbjct: 91   ESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQS--QQGSRGQN 148

Query: 2377 SSRGERHGSSSGSS--SSYGQHG-SGSRQSLGHGQHGSG-SGQSPSPSRGRHGSGSGQSS 2432
                +  G ++GS+  SSY +   S S++ +      SG + Q+     G+    +    
Sbjct: 149  RPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRP 208

Query: 2433 SYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGST 2492
               P       +   G   +GSG  +  G  ++    SS                Q G T
Sbjct: 209  ERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSH---------------QTGRT 253

Query: 2493 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG 2552
            S Q+       A++ Q+     HG G SQ+S     G    Q+  H Q  + + +  S  
Sbjct: 254  SKQTQE-----ATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSH 308

Query: 2553 RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQ 2612
            + GS S ++  S    +   E  G G  ++S   +  ++Q  +GS H+    Q  S++  
Sbjct: 309  QTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGS-HTETVEQDRSQTVS 367

Query: 2613 SSRGERHGSSS---GSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHG 2669
                   G +    GS   + Q  +     +  G Q   +G S   GR      H     
Sbjct: 368  HGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQ-TGASTESGRQEWSSTHPRRCV 426

Query: 2670 QHGSGSGRSSSRG-PYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS 2727
              G G  + +  G  +       +V  + + G+ H+S  S  G  +    S+ + G T+
Sbjct: 427  TEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQ--SEEKRGITA 483



 Score = 63.2 bits (152), Expect = 4e-09
 Identities = 98/414 (23%), Positives = 150/414 (36%), Gaps = 65/414 (15%)

Query: 1326 EGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGH-SSSYGQHG----- 1379
            EG+   Q S   H  SG+SQ  G G+          +G+H  GS H  S  G  G     
Sbjct: 94   EGACGSQESGSLH--SGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPG 151

Query: 1380 -------SGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSG---HSSSYEQ 1429
                   +GS W SS  R      Q        S   Q SG T+    +G    + + E 
Sbjct: 152  VQTQGQATGSAWVSSYDRQAESQSQ-----ERISPQIQLSGQTEQTQKAGEGKRNQTTEM 206

Query: 1430 HGSRSGQSSRGER-HGSSSGSSSSYGQHGSGSRQSL---GHGQHGSGSGQSPSPSRGR-- 1483
               R  Q+   +R H +    + S  Q  +G+ Q++      Q G  S Q+   +  +  
Sbjct: 207  RPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNR 266

Query: 1484 ----HGSGSGQSS-----SYSPYGSGSGWSSSRGPYESGSSHSSG---LGHRESRSGQSS 1531
                HG G  Q+S      ++   +G+   +     E  SSH +G      +ES +GQ+ 
Sbjct: 267  GTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNR 326

Query: 1532 GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG 1591
            G          +  HGQ  S + Q+ + G     +G  +   +     + S G  R+   
Sbjct: 327  G----------TEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQ 376

Query: 1592 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS 1651
            +   PG GQR      +P        +G +   GQ  +G    S  G  E SS       
Sbjct: 377  TQTQPGSGQRWM-QVSNPE-------AGETVPGGQAQTGASTES--GRQEWSSTHPRRCV 426

Query: 1652 QHGSGSGHSSGYGQH----GSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSG 1701
              G G    +  G+      SR     R ++    +  SS  GQ  + S +  G
Sbjct: 427  TEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRG 480



 Score = 63.2 bits (152), Expect = 4e-09
 Identities = 76/308 (24%), Positives = 122/308 (39%), Gaps = 32/308 (10%)

Query: 1641 ESSSGQSSSYSQHGSGSGHSSGYGQH-GSRSGQSSRGERHGSSSRSSSRYGQHG------ 1693
            E + G   S S H SG+    G GQ  G+  G++ +G+ +  SS   S+ G  G      
Sbjct: 94   EGACGSQESGSLH-SGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGV 152

Query: 1694 ------SGSRQSSGHGRQGSGSGQ---SPSRGRHG-SGLGHSSSHGQHGSGSGRSSSRGP 1743
                  +GS   S + RQ     Q   SP     G +     +  G+    +     R P
Sbjct: 153  QTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQP 212

Query: 1744 YESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQS 1803
                   +   G+  +GSG     +Q  +G+     Q     T G++S   QE ++  Q+
Sbjct: 213  QTREQDRAHQTGETVTGSG-----TQTQAGATQTVEQDSSHQT-GRTSKQTQEATND-QN 265

Query: 1804 SSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS 1863
                 HG G SQ+S     G    Q+ +  +  + +    S  Q GS S  +  S    +
Sbjct: 266  RGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQN 325

Query: 1864 GSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSY 1923
               +  G G  ++S   + G+TQ  +GS H+ + EQ  S++        HG +     + 
Sbjct: 326  RGTEIHGQGRSQTSQAVTGGHTQIQAGS-HTETVEQDRSQT------VSHGGAREQGQTQ 378

Query: 1924 GQHGSGSR 1931
             Q GSG R
Sbjct: 379  TQPGSGQR 386



 Score = 62.8 bits (151), Expect = 5e-09
 Identities = 105/452 (23%), Positives = 169/452 (37%), Gaps = 63/452 (13%)

Query: 1171 ESSSGQSSSYSQHGSGSGHSSGYGQH-GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQS 1229
            E + G   S S H SG+    G GQ  G+  G++ +G+ +    GSS    Q GS  +  
Sbjct: 94   EGACGSQESGSLH-SGASQELGEGQRSGTEVGRAGKGQHY---EGSSHRQSQQGSRGQNR 149

Query: 1230 SGHGRQG--SGSGHSPSRGRHGSGLGHSSSHGQ-HGSGSGRSSSRGPYESRSGHSSVFGQ 1286
             G   QG  +GS    S  R            Q   SG    + +     R+  + +  +
Sbjct: 150  PGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPE 209

Query: 1287 HESGSGHSSAYSQHG---SGSGHFCSQGQHGSTSGQSSTFDQEGS-STGQSSSYGHRGSG 1342
             +  +       Q G   +GSG   +Q Q G+T     T +Q+ S  TG++S      + 
Sbjct: 210  RQPQTREQDRAHQTGETVTGSG---TQTQAGAT----QTVEQDSSHQTGRTSKQTQEAT- 261

Query: 1343 SSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFG 1402
            + Q+ G   HG G  Q+      G     + ++ Q  + +    SS + GS S Q+    
Sbjct: 262  NDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQT---- 317

Query: 1403 HHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQ 1462
              ES++ Q+ G   HG G   +S                             Q  +G   
Sbjct: 318  -QESTNGQNRGTEIHGQGRSQTS-----------------------------QAVTGGHT 347

Query: 1463 SLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGH 1522
             +  G H     Q  S +   HG    Q  + +  GSG  W     P E+G +   G   
Sbjct: 348  QIQAGSHTETVEQDRSQTVS-HGGAREQGQTQTQPGSGQRWMQVSNP-EAGETVPGG--- 402

Query: 1523 RESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASS-GQSSSHGQHGSGSSQ 1581
             ++++G S+  G+   SS H       G    Q +  G+       + +   +   G+  
Sbjct: 403  -QAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLH 461

Query: 1582 SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 1613
            +S    QG  + QS    +RG  +R+  SY R
Sbjct: 462  TSVSSAQGQDAAQS--EEKRGITARELYSYLR 491



 Score = 62.4 bits (150), Expect = 6e-09
 Identities = 96/413 (23%), Positives = 157/413 (38%), Gaps = 31/413 (7%)

Query: 912  GSGRSSSSGRHGSGSGQSSGFGHKSSSGQS-SGYTQHGSGSGHSSSYEQHGSRSGQSSRS 970
            G+  S  SG   SG+ Q  G G +S +    +G  QH  GS H  S  Q GSR       
Sbjct: 95   GACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQS--QQGSRGQNRPGV 152

Query: 971  EQHGSSSGSS--SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYR 1028
            +  G ++GS+  SSY +      Q     Q    SGQ+    +   G  + Q++   P R
Sbjct: 153  QTQGQATGSAWVSSYDRQAESQSQERISPQIQL-SGQTEQTQKAGEGKRN-QTTEMRPER 210

Query: 1029 SGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSS 1088
                    R        H +G    E+ +G  +      + +    +  Q G TS Q+  
Sbjct: 211  QPQTREQDRA-------HQTG----ETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQE 259

Query: 1089 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 1148
                 A++ Q+     HG G SQ+S     G    Q+  H Q  + + +  S  + GS S
Sbjct: 260  -----ATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS 314

Query: 1149 GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1208
             ++  S    +   E  G G  ++S   +  ++Q  +GS H+    Q  S++        
Sbjct: 315  TQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGS-HTETVEQDRSQTVSHGGARE 373

Query: 1209 HGSSS---GSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGS 1265
             G +    GS   + Q  +     +  G Q   +G S   GR      H       G G 
Sbjct: 374  QGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQ-TGASTESGRQEWSSTHPRRCVTEGQGD 432

Query: 1266 GRSSSRG-PYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS 1317
             + +  G  +       +V  + + G+ H+S  S  G  +    S+ + G T+
Sbjct: 433  RQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQ--SEEKRGITA 483



 Score = 61.6 bits (148), Expect = 1e-08
 Identities = 97/414 (23%), Positives = 149/414 (35%), Gaps = 65/414 (15%)

Query: 2266 EGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGH-SSSYGQHG----- 2319
            EG+   Q S  G   SG+SQ    GQ+         +G+H  GS H  S  G  G     
Sbjct: 94   EGACGSQES--GSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPG 151

Query: 2320 -------SGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSG---HSSSYEQ 2369
                   +GS W SS  R      Q        S   Q SG T+    +G    + + E 
Sbjct: 152  VQTQGQATGSAWVSSYDRQAESQSQ-----ERISPQIQLSGQTEQTQKAGEGKRNQTTEM 206

Query: 2370 HGSRSGQSSRGER-HGSSSGSSSSYGQHGSGSRQSL---GHGQHGSGSGQSPSPSRGR-- 2423
               R  Q+   +R H +    + S  Q  +G+ Q++      Q G  S Q+   +  +  
Sbjct: 207  RPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNR 266

Query: 2424 ----HGSGSGQSS-----SYSPYGSGSGWSSSRGPYESGSGHSSG---LGHRESRSGQSS 2471
                HG G  Q+S      ++   +G+   +     E  S H +G      +ES +GQ+ 
Sbjct: 267  GTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNR 326

Query: 2472 GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG 2531
            G          +  HGQ  S + Q+ + G     +G  +   +     + S G  R+   
Sbjct: 327  G----------TEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQ 376

Query: 2532 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS 2591
            +   PG GQR      +P        +G +   GQ  +G    S  G  E SS       
Sbjct: 377  TQTQPGSGQRWM-QVSNPE-------AGETVPGGQAQTGASTES--GRQEWSSTHPRRCV 426

Query: 2592 QHGSGSGHSSGYGQH----GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSG 2641
              G G    +  G+      SR     R ++    +  SS  GQ  + S +  G
Sbjct: 427  TEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRG 480



 Score = 61.6 bits (148), Expect = 1e-08
 Identities = 73/326 (22%), Positives = 118/326 (36%), Gaps = 29/326 (8%)

Query: 564 GSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGH-SSTHGQHG------ST 616
           G+  S   G   SG+    G G +       +G GQH   S H  S  G  G       T
Sbjct: 95  GACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQT 154

Query: 617 SGQSSSCGQHGATSGQSSSHGQH----------GSGSSQSSRYGQQGSGSGQSPSRGRHG 666
            GQ++      +   Q+ S  Q            +  +Q +  G++   +   P R    
Sbjct: 155 QGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQT 214

Query: 667 SDFGHSSSYGQHGSGSGWSSSNGPHGSV-------SGQSSGFGHKSGSGQSSGYSQHGSG 719
            +   +   G+  +GSG  +  G   +V       +G++S    ++ + Q+ G   HG G
Sbjct: 215 REQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQG 274

Query: 720 SSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQ----SSGHGRQGSGSGHS 775
            S +S     G    Q+    Q  + +    S  Q GS S Q    ++G  R     G  
Sbjct: 275 RSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQG 334

Query: 776 PSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSAS 835
            S+     + GH+       + T           G  +  G  Q + GSGQ + Q  +  
Sbjct: 335 RSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPE 394

Query: 836 GHFSSQGRHGSTSGQSSSSGQHDSSS 861
              +  G    T G S+ SG+ + SS
Sbjct: 395 AGETVPGGQAQT-GASTESGRQEWSS 419



 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 97/395 (24%), Positives = 143/395 (36%), Gaps = 62/395 (15%)

Query: 860  SSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSS 919
            S     + G  ES S H        SG+ Q  G GQR SG+      GR G G     SS
Sbjct: 90   SESAEGACGSQESGSLH--------SGASQELGEGQR-SGT----EVGRAGKGQHYEGSS 136

Query: 920  GRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGS 979
             R      Q    G      Q+ G     +GS   SSY++      Q   S Q    SG 
Sbjct: 137  HR----QSQQGSRGQNRPGVQTQG---QATGSAWVSSYDRQAESQSQERISPQI-QLSGQ 188

Query: 980  SSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRG- 1038
            +    + G G R                 P R        ++   G   +GSG  +  G 
Sbjct: 189  TEQTQKAGEGKRNQT----------TEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGA 238

Query: 1039 --PYESGSGHSSGLGHR---ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHG 1093
                E  S H +G   +   E+ + Q+ G   HG     +S     G    Q+ +  Q  
Sbjct: 239  TQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTP 298

Query: 1094 ASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG---HGQRGSGSRQSPSYGRHGSGSGR 1150
              + +  S  Q GS S+Q+     Q S +GQ+ G   HGQ  S + Q+ + G     +G 
Sbjct: 299  TQTVEQDSSHQTGSTSTQT-----QESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGS 353

Query: 1151 SSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG----------SGHSSGYGQHGSRS 1200
             + + +      + S    H  +  Q  + +Q GSG          +G +   GQ  +++
Sbjct: 354  HTETVEQ-----DRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQ--AQT 406

Query: 1201 GQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQ 1235
            G S+   R   SS         G G RQ +  G +
Sbjct: 407  GASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEE 441



 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 98/415 (23%), Positives = 144/415 (34%), Gaps = 67/415 (16%)

Query: 1796 EGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGH-SSSYGQHG----- 1849
            EG+   Q S  G   SG+SQ    GQ+         +G+H  GS H  S  G  G     
Sbjct: 94   EGACGSQES--GSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPG 151

Query: 1850 -------SGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSG---HSSSYEQ 1899
                   +GS W SS  R      Q        S   Q SG T+    +G    + + E 
Sbjct: 152  VQTQGQATGSAWVSSYDRQAESQSQ-----ERISPQIQLSGQTEQTQKAGEGKRNQTTEM 206

Query: 1900 HGSRSGQS---SRGEQHGSSSGSSSSYGQHGSGS--RQSLGHGQHGSGSGQSPSPSRGR- 1953
               R  Q+    R  Q G +   S +  Q G+     Q   H Q G  S Q+   +  + 
Sbjct: 207  RPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSH-QTGRTSKQTQEATNDQN 265

Query: 1954 -----HGSGSGQSS-----SYGPYGSGSGWSSSRGPYESGSGHSSG---LGHRESRSGQS 2000
                 HG G  Q+S      +    +G+   +     E  S H +G      +ES +GQ+
Sbjct: 266  RGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQN 325

Query: 2001 SGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS 2060
             G          +  HGQ  S + Q+ + G     +G  +   +     + S G  R+  
Sbjct: 326  RG----------TEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQG 375

Query: 2061 GSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSY 2120
             +   PG GQR      +P  G    G    +         G S+  G  E SS      
Sbjct: 376  QTQTQPGSGQRWM-QVSNPEAGETVPGGQAQT---------GASTESGRQEWSSTHPRRC 425

Query: 2121 SQHGSGSGHSSGYGQH----GSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSG 2171
               G G    +  G+      SR     R ++    +  SS  GQ  + S +  G
Sbjct: 426  VTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRG 480



 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 94/416 (22%), Positives = 149/416 (35%), Gaps = 28/416 (6%)

Query: 2152 SSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGH-SSSHGQHGSGS-GRS- 2208
            S  +    G   SGS  S      G G       GR G G  +  SSH Q   GS G++ 
Sbjct: 90   SESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNR 149

Query: 2209 ---SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 2265
                ++G     +  SS   Q ES S    +     SG      +   G  +  +    +
Sbjct: 150  PGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPE 209

Query: 2266 EGSSTGQSSSHGQHGSGSSQSSSYGQQGS-------GSGQSPSRGRHGSGSGHSSSYGQH 2318
                T +     Q G   + S +  Q G+        S Q+    +    + +  + G  
Sbjct: 210  RQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTE 269

Query: 2319 GSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSS 2378
              G G S +S     G  Q     H ++ +      + H +GS  + + E   S +GQ+ 
Sbjct: 270  THGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQE---STNGQNR 326

Query: 2379 RGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYG 2438
              E HG     +S   Q  +G    +  G H     Q  S +   HG    Q  + +  G
Sbjct: 327  GTEIHGQGRSQTS---QAVTGGHTQIQAGSHTETVEQDRSQTVS-HGGAREQGQTQTQPG 382

Query: 2439 SGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSS 2498
            SG  W     P E+G     G    ++++G S+  G+   SS H       G    Q + 
Sbjct: 383  SGQRWMQVSNP-EAGETVPGG----QAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTV 437

Query: 2499 CGQHGASS-GQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 2553
             G+       + +   +   G+  +S    QG  + QS    +RG  +R+  SY R
Sbjct: 438  VGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQS--EEKRGITARELYSYLR 491



 Score = 58.5 bits (140), Expect = 9e-08
 Identities = 89/408 (21%), Positives = 144/408 (35%), Gaps = 34/408 (8%)

Query: 2435 SPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGH-SSTHGQHGSTS 2493
            S    G+  S   G   SG+    G G R       +G GQH   S H  S  G  G   
Sbjct: 90   SESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNR 149

Query: 2494 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG---SGQSPGHGQRGSGSRQSPS 2550
                + GQ   S+  SS   Q  S S +      Q SG     Q  G G+R   +   P 
Sbjct: 150  PGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPE 209

Query: 2551 YGRHGSGSGRSSSSGQHGSGLGESSGFGHHES-------SSGQSSSYSQHGSGSGHSSGY 2603
                     R+  +G+  +G G  +  G  ++        +G++S  +Q  + +  + G 
Sbjct: 210  RQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEAT-NDQNRGT 268

Query: 2604 GQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLG 2663
              HG    Q+S+    G +   +  + Q  + + +     + GS S Q+     +G   G
Sbjct: 269  ETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQT-QESTNGQNRG 327

Query: 2664 HSSSHGQHGSGSGRSSSRGPYESRLG-HSSVFGQHES-----GSGHSSAYSQHGSGSGHF 2717
             +  HGQ  S + ++ + G  + + G H+    Q  S     G       +Q   GSG  
Sbjct: 328  -TEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSG-- 384

Query: 2718 CSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGS 2777
              +    S      T     + TG S+  G +   S+        G G  Q    G    
Sbjct: 385  -QRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWV 443

Query: 2778 GS----------GQSSSYGQHGSGSGQSSGYSQHGSG-SGQDGYSYCK 2814
                         Q + +    S  GQ +  S+   G + ++ YSY +
Sbjct: 444  DDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRGITARELYSYLR 491



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 93/410 (22%), Positives = 148/410 (36%), Gaps = 52/410 (12%)

Query: 607 SSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHG 666
           S   G   S + Q    GQ   T    +  GQH  GSS   R  QQGS     P     G
Sbjct: 99  SQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSH--RQSQQGSRGQNRPGVQTQG 156

Query: 667 SDFGHS--SSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQ--------- 715
              G +  SSY +          + P   +SGQ+     K+G G+ +  ++         
Sbjct: 157 QATGSAWVSSYDRQAESQSQERIS-PQIQLSGQTEQT-QKAGEGKRNQTTEMRPERQPQT 214

Query: 716 HGSGSSHSSGYRKHGS----RSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSG 771
                +H +G    GS    ++G +   EQ  S     +S     + + Q+ G    G G
Sbjct: 215 REQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQG 274

Query: 772 SGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQH 831
              +   V  G +   + +H Q  + T    S     S S Q     +  +G  +G   H
Sbjct: 275 RSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQ---ESTNGQNRGTEIH 331

Query: 832 GSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSP 891
           G        QGR  S + Q+ + G     +G  +   + + +   + G  R    +   P
Sbjct: 332 G--------QGR--SQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQP 381

Query: 892 GHGQR-----GSGSGQSPSYGRHGSG----SGRSSSSGRH-------GSGSGQSSGFGHK 935
           G GQR        +G++   G+  +G    SGR   S  H       G G  Q +  G +
Sbjct: 382 GSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEE 441

Query: 936 --SSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSY 983
                 + +   +   G+ H+S     G  + QS   E+ G ++    SY
Sbjct: 442 WVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQS--EEKRGITARELYSY 489



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 97/401 (24%), Positives = 154/401 (38%), Gaps = 46/401 (11%)

Query: 1101 SHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS----GRSSSSGQ 1156
            S    G+  SQ SG     SG+ Q  G GQR          G+H  GS     +  S GQ
Sbjct: 90   SESAEGACGSQESG--SLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQ 147

Query: 1157 HGSGL---GESSGFGHHESSSGQSSSYSQHG-SGSGHSSGYGQHGSRSGQSSRGERHGSS 1212
            +  G+   G+++G     S   Q+ S SQ   S     SG  +   ++G+   G+R+ ++
Sbjct: 148  NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGE---GKRNQTT 204

Query: 1213 SGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRG 1272
                    Q     R +   G   +GSG     G   + +   SSH Q G  S ++    
Sbjct: 205  EMRPERQPQTREQDR-AHQTGETVTGSGTQTQAGATQT-VEQDSSH-QTGRTSKQTQEAT 261

Query: 1273 PYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ-----HGSTSGQSSTFDQEG 1327
              ++R   +   G+ ++    +  ++Q  +G+ H  +  Q         +G +ST  QE 
Sbjct: 262  NDQNRGTETHGQGRSQTSQAVTGGHAQIQAGT-HTQTPTQTVEQDSSHQTGSTSTQTQE- 319

Query: 1328 SSTGQSSSYGHRGSGSSQSS-----GYGRHGAGS-GQSPSRGR-----HGSGSGHSSSYG 1376
            S+ GQ+      G G SQ+S     G+ +  AGS  ++  + R     HG       +  
Sbjct: 320  STNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQT 379

Query: 1377 QHGSGSGWSSSSGRHG--------SGSGQSSGFGHHESSSWQSSGCTQHGSGSGH----S 1424
            Q GSG  W   S            + +G S+  G  E SS     C   G G        
Sbjct: 380  QPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVG 439

Query: 1425 SSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLG 1465
              +    SR     R ++    +  SS+ GQ  + S +  G
Sbjct: 440  EEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRG 480



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 90/417 (21%), Positives = 143/417 (34%), Gaps = 51/417 (12%)

Query: 1414 CTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1473
            C    SGS HS + ++ G        G+R G+  G +              G GQH  GS
Sbjct: 97   CGSQESGSLHSGASQELGE-------GQRSGTEVGRA--------------GKGQHYEGS 135

Query: 1474 G--QSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSS 1531
               QS   SRG++  G           +GS W SS    ++ S     +  +   SGQ+ 
Sbjct: 136  SHRQSQQGSRGQNRPGVQTQGQ----ATGSAWVSSY-DRQAESQSQERISPQIQLSGQTE 190

Query: 1532 GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG 1591
               + G    + +T  +             H      + S  Q  +G++Q+     +   
Sbjct: 191  QTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTV----EQDS 246

Query: 1592 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS 1651
            S Q+    ++   +    + G    G GRS +S     G  +     H ++ +      S
Sbjct: 247  SHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDS 306

Query: 1652 QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQ-GSGSG 1710
             H +GS  +       S +GQ+   E HG     +S+    G    Q+  H         
Sbjct: 307  SHQTGSTSTQ---TQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRS 363

Query: 1711 QSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPY--------ESRSGHSSVFGQHESGSG 1762
            Q+ S   HG       +  Q GSG        P         ++++G S+  G+ E  S 
Sbjct: 364  QTVS---HGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSST 420

Query: 1763 HSSAYSQHGSGSGHFCSQGQHGSTSGQSST----FDQEGSSTGQSSSHGQHGSGSSQ 1815
            H       G G       G+         T     DQ    T  SS+ GQ  + S +
Sbjct: 421  HPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEE 477



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 97/422 (22%), Positives = 154/422 (36%), Gaps = 68/422 (16%)

Query: 962  SRSGQSSRSEQHGSSSGSSSSYGQ-HGSGSRQS-LGHGQHGSGSG--QSPSPSRGRH--- 1014
            S  G     E     SG+S   G+   SG+     G GQH  GS   QS   SRG++   
Sbjct: 92   SAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPG 151

Query: 1015 ------GSGSGQSSSYGPYRSGSGWSSSR-GPYESGSGHS-----SGLG----------H 1052
                   +GS   SSY   R     S  R  P    SG +     +G G           
Sbjct: 152  VQTQGQATGSAWVSSYD--RQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPE 209

Query: 1053 RESRSGQSSGYGQHGSSSGHSSTHGQHGST-SGQSSSCGQHGASSGQSSSHGQHGSGSSQ 1111
            R+ ++ +     Q G +   S T  Q G+T + +  S  Q G +S Q+       +  ++
Sbjct: 210  RQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTE 269

Query: 1112 SSGYGRQGSGSGQSPGHGQRGSGSR-QSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 1170
            + G GR  +    + GH Q  +G+  Q+P+       +    SS Q GS   ++      
Sbjct: 270  THGQGRSQTSQAVTGGHAQIQAGTHTQTPTQ------TVEQDSSHQTGSTSTQT-----Q 318

Query: 1171 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS 1230
            ES++GQ+     HG G           S++ Q+  G      +GS +   +       S 
Sbjct: 319  ESTNGQNRGTEIHGQGR----------SQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSH 368

Query: 1231 GHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG 1290
            G  R+   +   P  G+    + +  + G+   G          ++++G S+  G+ E  
Sbjct: 369  GGAREQGQTQTQPGSGQRWMQVSNPEA-GETVPGG---------QAQTGASTESGRQEWS 418

Query: 1291 SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSST----FDQEGSSTGQSSSYGHRGSGSSQS 1346
            S H       G G       G+         T     DQ    T  SS+ G   + S + 
Sbjct: 419  STHPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEK 478

Query: 1347 SG 1348
             G
Sbjct: 479  RG 480



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 87/379 (22%), Positives = 136/379 (35%), Gaps = 46/379 (12%)

Query: 2284 SQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGH 2343
            S   + G Q SGS  S +    G G    +  G+ G G  +  SS R         G   
Sbjct: 92   SAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQ-----SQQGSRG 146

Query: 2344 HESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQS 2403
                  Q+ G     +GS   SSY+    R  +S   ER       S    Q      Q 
Sbjct: 147  QNRPGVQTQG---QATGSAWVSSYD----RQAESQSQERISPQIQLSGQTEQ-----TQK 194

Query: 2404 LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGS-GWSSSRGPYESGSGHSSGLGH 2462
             G G+    +   P              +  +  GSG+   + +    E  S H +G   
Sbjct: 195  AGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTS 254

Query: 2463 R---ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGS 2519
            +   E+ + Q+ G   HG     +S     G    Q+ +  Q    + +  S  Q GS S
Sbjct: 255  KQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS 314

Query: 2520 SQSSGYGRQGSGSGQSPG---HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSG 2576
            +Q+     Q S +GQ+ G   HGQ  S + Q+ + G     +G  + + +      + S 
Sbjct: 315  TQT-----QESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQ-----DRSQ 364

Query: 2577 FGHHESSSGQSSSYSQHGSG----------SGHSSGYGQHGSRSGQSSRGERHGSSSGSS 2626
               H  +  Q  + +Q GSG          +G +   GQ  +++G S+   R   SS   
Sbjct: 365  TVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQ--AQTGASTESGRQEWSSTHP 422

Query: 2627 SHYGQHGSGSRQSSGHGRQ 2645
                  G G RQ +  G +
Sbjct: 423  RRCVTEGQGDRQPTVVGEE 441



 Score = 53.5 bits (127), Expect = 3e-06
 Identities = 87/403 (21%), Positives = 138/403 (34%), Gaps = 34/403 (8%)

Query: 1902 SRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSL-----GHGQHGSGSG--QSPSPSRGRH 1954
            S S + + G Q   S  S +S  + G G R        G GQH  GS   QS   SRG++
Sbjct: 90   SESAEGACGSQESGSLHSGASQ-ELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQN 148

Query: 1955 GSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 2014
              G           +GS W SS    ++ S     +  +   SGQ+    + G    + +
Sbjct: 149  RPGVQTQGQ----ATGSAWVSSY-DRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQT 203

Query: 2015 THGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSG 2074
            T  +             H      + S  Q  +G++Q+     +   S Q+    ++   
Sbjct: 204  TEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTV----EQDSSHQTGRTSKQTQE 259

Query: 2075 SRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYG 2134
            +    + G    G GRS +S     G  +     H ++ +      S H +GS  +    
Sbjct: 260  ATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQ--- 316

Query: 2135 QHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGH 2194
               S +GQ+   E HG     +S+    G    Q+  H    +          HG     
Sbjct: 317  TQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTE--TVEQDRSQTVSHGGAREQ 374

Query: 2195 SSSHGQHGSGSGRSSSRGPY--------ESRSGHSSVFGQHESGSGHSSAYSQHGSGSGH 2246
              +  Q GSG        P         ++++G S+  G+ E  S H       G G   
Sbjct: 375  GQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQ 434

Query: 2247 FCSQGQHGSTSGQSST----FDQEGSSTGQSSSHGQHGSGSSQ 2285
                G+         T     DQ    T  SS+ GQ  + S +
Sbjct: 435  PTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEE 477



 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 67/278 (24%), Positives = 103/278 (37%), Gaps = 30/278 (10%)

Query: 2557 GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 2616
            G+  S  SG   SG  +  G G    +    +   QH  GS H     Q GSR       
Sbjct: 95   GACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQS--QQGSRGQNRPGV 152

Query: 2617 ERHGSSSGS---SSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGS 2673
            +  G ++GS   SS+  Q  S S++      Q SG  +   +          +  G+   
Sbjct: 153  QTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQK----------AGEGKRNQ 202

Query: 2674 GSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF 2733
             +     R P       +   G+  +GSG     +Q  +G+     Q     T G++S  
Sbjct: 203  TTEMRPERQPQTREQDRAHQTGETVTGSG-----TQTQAGATQTVEQDSSHQT-GRTSKQ 256

Query: 2734 DQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGS- 2792
             QE ++     +  H G G SQ+S     G    Q+ +H +  + + +  S  Q GS S 
Sbjct: 257  TQEATNDQNRGTETH-GQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTST 315

Query: 2793 -------GQSSGYSQHGSGSGQDGYSYCKGGSNHDGGS 2823
                   GQ+ G   HG G  Q   +   G +    GS
Sbjct: 316  QTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGS 353



 Score = 48.9 bits (115), Expect = 7e-05
 Identities = 92/414 (22%), Positives = 139/414 (33%), Gaps = 46/414 (11%)

Query: 1064 GQHGSSSGHSST-----HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 1118
            G   S S HS        GQ   T    +  GQH    G S    Q GS      G   Q
Sbjct: 98   GSQESGSLHSGASQELGEGQRSGTEVGRAGKGQH--YEGSSHRQSQQGSRGQNRPGVQTQ 155

Query: 1119 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSS 1178
                GQ+ G     S  RQ+ S  +    S +   SGQ  +   + +G G    ++    
Sbjct: 156  ----GQATGSAWVSSYDRQAESQSQERI-SPQIQLSGQ--TEQTQKAGEGKRNQTTEMRP 208

Query: 1179 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSG 1238
                       +   G+  + SG  ++     +    SSH  Q G  S+Q+       + 
Sbjct: 209  ERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSH--QTGRTSKQTQEATNDQNR 266

Query: 1239 SGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGH---SSVFGQHESGSGHSS 1295
               +  +GR  +    +  H Q  +G+   +     E  S H   S+     ES +G + 
Sbjct: 267  GTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNR 326

Query: 1296 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST-----GQSSSYGHRGSGSSQSSGYG 1350
                HG G     SQ     T G +    Q GS T      +S +  H   G ++  G  
Sbjct: 327  GTEIHGQGR----SQTSQAVTGGHTQI--QAGSHTETVEQDRSQTVSH---GGAREQGQT 377

Query: 1351 RHGAGSGQ------SPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 1404
            +   GSGQ      +P  G    G    +          WSS+  R     GQ       
Sbjct: 378  QTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTV 437

Query: 1405 ESSSW-----QSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSY 1453
                W     + +   +   G+ H+S     G  + QS   E+ G ++    SY
Sbjct: 438  VGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSE--EKRGITARELYSY 489


>gi|239757861 PREDICTED: similar to armadillo repeat containing,
            X-linked 4 [Homo sapiens]
          Length = 2382

 Score =  117 bits (293), Expect = 2e-25
 Identities = 181/728 (24%), Positives = 255/728 (35%), Gaps = 80/728 (10%)

Query: 1687 SRYGQHGSGSRQSSGHGRQGSGSGQSPSRG------RHGSG----LGHSSSHGQHGSGSG 1736
            +R G+  SG   + G   +G+ +G   S G         SG    L  + + G+  +   
Sbjct: 1273 ARAGEQASGGLWAGGQTSEGTWAGDKASGGAWTGAENQASGGSWALAGNQAIGELWAAGQ 1332

Query: 1737 RSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQE 1796
             S    P    SG S V G+   G   + A +Q   GS      G   S S  +   DQ 
Sbjct: 1333 ASDGSWPGGQASGVSWV-GEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQA 1391

Query: 1797 GSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS 1856
            G  +   +S  Q G GS     +  Q SG G     G   SG        Q  SG  W+ 
Sbjct: 1392 GGGSWAGTSD-QSGGGSKPR--FEDQASGEGSWAGAGGQASGGSMLGPEDQ-SSGRSWAD 1447

Query: 1857 SSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSS 1916
            ++ +   GS      GH + SS  +   T   SG G    +E   +  G  +     G  
Sbjct: 1448 TADQASGGSR----LGHVDQSSGGAWAGTLDQSGGGSKPRFENQTTEEGSWAGA---GGQ 1500

Query: 1917 SGSSSSYGQHGSGSRQSLGH-GQHGSGSGQSPSPSRGRHGS--GSGQSSSYGPYGSGSGW 1973
            +G  S  G     S +S  + G   SG        +   GS  G+G  +S GP       
Sbjct: 1501 AGGGSKVGPEDQSSGRSWANSGDQISGGFLVGIVDQANGGSWTGAGHPASVGPKPIFEDQ 1560

Query: 1974 SSSRGPYESGSGHSSG---LGHRESRSGQS-SGYGQHGSS-----SGHSSTHGQHGSASG 2024
             S RG +        G   LG R+  SG S +G G   S       G  +  G  G ASG
Sbjct: 1561 VSGRGSWADAREQVVGDSRLGLRDQSSGDSWAGTGDQASGWFCVCPGSQTNGGSWGGASG 1620

Query: 2025 QSSSCGQHG----ASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPS 2080
            Q     + G    +S+G   S G   SGS  +       +G    PG   +  G    P 
Sbjct: 1621 QDVGGSRPGPTNQSSAGSWDSPGSQVSGSCWTGAGAVDQAGGCSKPGFEDQAIGGGFWPG 1680

Query: 2081 YGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG--YGQHGS 2138
             G    G  R  S  Q       SSG G    + GQ    ++ G     S G   G    
Sbjct: 1681 AGDQTGGGSRPGSEDQ-------SSGIGSWGVAGGQVLGGARPGPADQSSGGSWAGTGNQ 1733

Query: 2139 RSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSR-GRHGSGSGHSSS 2197
             SG+S  G    +   S   +     G    +G G Q SG   + SR G    G     S
Sbjct: 1734 SSGRSWIGPGDQAVDCSKPEFEDQACGGGSWAGAGSQASGESWAGSRPGNEAIGGSRMGS 1793

Query: 2198 HGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS----GHFC----- 2248
              Q   GS   S     +  SG   V  + E+  G        G G+    G +C     
Sbjct: 1794 EDQATGGSWARSE----DQASGRFQVSFEVEANEGF-----WFGPGAEAVIGSWCWTEEK 1844

Query: 2249 ------SQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGS-SQSSSYGQQGSGSGQSPS 2301
                     +  +T+   S   +E     +  +  +  SGS  +S      GS  G    
Sbjct: 1845 ADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVGAEAG 1904

Query: 2302 RGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYT-QHGSG 2360
             G   +G+G  +  G  G+ +G  + +G  G+G G  SG G     SW     T +   G
Sbjct: 1905 AGAE-AGAGAEAGAGA-GAEAGAEAGAGA-GAGPGTESGAG---VWSWDGDATTVESRLG 1958

Query: 2361 SGHSSSYE 2368
            +G  +  E
Sbjct: 1959 AGEEAGVE 1966



 Score =  105 bits (263), Expect = 5e-22
 Identities = 179/779 (22%), Positives = 270/779 (34%), Gaps = 94/779 (12%)

Query: 1262 GSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS 1321
            GS SG S   G   S +    V     S    + A +++  G G +   G+  S    + 
Sbjct: 1231 GSWSGASDKAGIIRSWA----VACDETSVKSWAGARAENVVGIGTWARAGEQASGGLWAG 1286

Query: 1322 TFDQEGSSTGQSSSYGHRGSGSSQSSG-----YGRHGAGSGQSPSRGRHGSGSGHSSS-- 1374
                EG+  G  +S G      +Q+SG      G    G   +  +   GS  G  +S  
Sbjct: 1287 GQTSEGTWAGDKASGGAWTGAENQASGGSWALAGNQAIGELWAAGQASDGSWPGGQASGV 1346

Query: 1375 --YGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGS 1432
               G+   G  W+ +  +   GS   +G G+  S S+ +    Q G GS   +S +  G 
Sbjct: 1347 SWVGEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGGGSWAGTSDQSGG- 1405

Query: 1433 RSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSS 1492
              G   R E   S  GS +  G   SG    LG     SG   + +  +   GS  G   
Sbjct: 1406 --GSKPRFEDQASGEGSWAGAGGQASGG-SMLGPEDQSSGRSWADTADQASGGSRLG--- 1459

Query: 1493 SYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGST 1552
             +    SG  W        +G+   SG G +     Q++   + GS +G     G     
Sbjct: 1460 -HVDQSSGGAW--------AGTLDQSGGGSKPRFENQTT---EEGSWAGAGGQAGGGSKV 1507

Query: 1553 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG 1612
              +  S G+  A+SG   S G       Q++G    G+G   S G           P + 
Sbjct: 1508 GPEDQSSGRSWANSGDQISGGFLVGIVDQANGGSWTGAGHPASVG---------PKPIFE 1558

Query: 1613 RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS-SSYSQHGSG-----SGHSSGYGQH 1666
               SG G  + + +   G    S  G  + SSG S +      SG      G  +  G  
Sbjct: 1559 DQVSGRGSWADAREQVVG---DSRLGLRDQSSGDSWAGTGDQASGWFCVCPGSQTNGGSW 1615

Query: 1667 GSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSG----SGQSPSRGRHGSGL 1722
            G  SGQ   G R G +++SS+  G   S   Q SG    G+G    +G     G     +
Sbjct: 1616 GGASGQDVGGSRPGPTNQSSA--GSWDSPGSQVSGSCWTGAGAVDQAGGCSKPGFEDQAI 1673

Query: 1723 GHSSSHGQHGSGSGRSSSRGPYESRSGHSS--VFGQHESGSGHSSAYSQHGSGSGHFCSQ 1780
            G     G  G  +G  S  G  +  SG  S  V G    G        Q   GS      
Sbjct: 1674 GGGFWPGA-GDQTGGGSRPGSEDQSSGIGSWGVAGGQVLGGARPGPADQSSGGSW----A 1728

Query: 1781 GQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSG 1840
            G    +SG+S     + +             G    +  G Q SG   + SR  + +  G
Sbjct: 1729 GTGNQSSGRSWIGPGDQAVDCSKPEFEDQACGGGSWAGAGSQASGESWAGSRPGNEAIGG 1788

Query: 1841 HSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG---------YTQHGSGS 1891
                     +G  W+ S  +  SG  Q S         W   G         +T+  +  
Sbjct: 1789 SRMGSEDQATGGSWARSEDQ-ASGRFQVSFEVEANEGFWFGPGAEAVIGSWCWTEEKADI 1847

Query: 1892 GHSSSYEQHGSRSGQSSRGE----------QHGSSSGS---SSSYGQHGSGSRQSLGHGQ 1938
                  +   + + +S  GE          ++ +SSGS   S      GS      G G 
Sbjct: 1848 VSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVGAEAGAGA 1907

Query: 1939 HGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSG-----WSSSRGPYES--GSGHSSGL 1990
                  ++ + +    G+ +G  +  GP G+ SG     W       ES  G+G  +G+
Sbjct: 1908 EAGAGAEAGAGAGAEAGAEAGAGAGAGP-GTESGAGVWSWDGDATTVESRLGAGEEAGV 1965



 Score =  104 bits (259), Expect = 1e-21
 Identities = 184/769 (23%), Positives = 274/769 (35%), Gaps = 89/769 (11%)

Query: 297  GRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSG----FGQHE 352
            G Q SG   +      G+ +G  +S G   +G+    S G +     Q  G     GQ  
Sbjct: 1276 GEQASGGLWAGGQTSEGTWAGDKASGGAW-TGAENQASGGSWALAGNQAIGELWAAGQAS 1334

Query: 353  SGS---GQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRH 409
             GS   GQ+SG S  G  +   S  G     S  + +    G+ S  S   G  + A   
Sbjct: 1335 DGSWPGGQASGVSWVGEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGGG 1394

Query: 410  SSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHE 469
            S       SG G  P    + SG G    +G   +G    S  GP    SG S      +
Sbjct: 1395 SWAGTSDQSGGGSKPRFEDQASGEGSWAGAGGQASG---GSMLGPEDQSSGRSWADTADQ 1451

Query: 470  SSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGS-SSSYGQHGSGSR--- 525
            +S     G+    SG   +    Q G   G   R E Q +  GS + + GQ G GS+   
Sbjct: 1452 ASGGSRLGHVDQSSGGAWAGTLDQSG--GGSKPRFENQTTEEGSWAGAGGQAGGGSKVGP 1509

Query: 526  --QSLGHSRHGSGSGQS-------PSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES 576
              QS G S   SG   S          + G   +G+   +S GP      + S RG +  
Sbjct: 1510 EDQSSGRSWANSGDQISGGFLVGIVDQANGGSWTGAGHPASVGPKPIFEDQVSGRGSWAD 1569

Query: 577  GSGH---SSGLGHQESRSGQS-SGYGQHGSS-----SGHSSTHGQHGSTSGQSSSCGQHG 627
                    S LG ++  SG S +G G   S       G  +  G  G  SGQ     + G
Sbjct: 1570 AREQVVGDSRLGLRDQSSGDSWAGTGDQASGWFCVCPGSQTNGGSWGGASGQDVGGSRPG 1629

Query: 628  ATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSS 687
             T+   SS G   S  SQ S     G+G+    + G     F   +  G    G+G  + 
Sbjct: 1630 PTN--QSSAGSWDSPGSQVSGSCWTGAGA-VDQAGGCSKPGFEDQAIGGGFWPGAGDQTG 1686

Query: 688  NGPHGSVSGQSSGFGHKS-GSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSS 746
             G       QSSG G      GQ  G ++ G  +  SSG    G+ +  S RS       
Sbjct: 1687 GGSRPGSEDQSSGIGSWGVAGGQVLGGARPGP-ADQSSGGSWAGTGNQSSGRSWIGPGDQ 1745

Query: 747  GLSSS---YGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSS 803
             +  S   +     G    +G G Q SG   +      GS  G+ +  G    G+   ++
Sbjct: 1746 AVDCSKPEFEDQACGGGSWAGAGSQASGESWA------GSRPGNEAIGGSR-MGSEDQAT 1798

Query: 804  CGHYESGSGQASGFGQ--HESGSGQGYSQHGSASGHFSS--------------QGRHGST 847
             G +     QASG  Q   E  + +G+     A     S                +  +T
Sbjct: 1799 GGSWARSEDQASGRFQVSFEVEANEGFWFGPGAEAVIGSWCWTEEKADIVSRPDDKDEAT 1858

Query: 848  SGQSSSSGQ--------HDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSG 899
            +   S +G+           +   S S+ + E  ++  S  G       ++    + G+G
Sbjct: 1859 TASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVGAEAGAGAEAGAGAEAGAG 1918

Query: 900  SG-QSPSYGRHGSGSGRSSSSGR-----HGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGH 953
            +G ++ +    G+G+G  + SG       G  +   S  G    +G  S       G   
Sbjct: 1919 AGAEAGAEAGAGAGAGPGTESGAGVWSWDGDATTVESRLGAGEEAGVESWTLARNVGEDE 1978

Query: 954  -----SSSYEQHGSRS---GQSSRSEQHGSSSGSSSSYGQHGSGSRQSL 994
                 S   E+   RS    +S  S    S SG  +S+ + G+G   S+
Sbjct: 1979 LSRESSPDIEEISLRSLFWAESENSNTFRSKSGKDASF-ESGAGDNTSI 2026



 Score = 99.8 bits (247), Expect = 4e-20
 Identities = 181/751 (24%), Positives = 261/751 (34%), Gaps = 94/751 (12%)

Query: 1836 GSGSGHSSSYG---------QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQ 1886
            GS SG S   G            S   W+ +   +  G G  +  G   S    + G T 
Sbjct: 1231 GSWSGASDKAGIIRSWAVACDETSVKSWAGARAENVVGIGTWARAGEQASGGLWAGGQTS 1290

Query: 1887 HGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQS 1946
             G+ +G  +S        G +  G ++ +S GS +  G    G   + G    GS  G  
Sbjct: 1291 EGTWAGDKAS--------GGAWTGAENQASGGSWALAGNQAIGELWAAGQASDGSWPG-- 1340

Query: 1947 PSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRS------GQS 2000
                    G  SG S   G    G  W+ +      GS   +G G+  S S       Q+
Sbjct: 1341 --------GQASGVSW-VGEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQA 1391

Query: 2001 SGYGQHGSS--SGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 2058
             G    G+S  SG  S       ASG+ S  G  G +SG S    +  S     +    Q
Sbjct: 1392 GGGSWAGTSDQSGGGSKPRFEDQASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTADQ 1451

Query: 2059 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGS-----GRSSSSGQHGPGLGESSGFGHHESS 2113
             SG G   GH  + SG   + +  + G GS      +++  G    G G  +G G     
Sbjct: 1452 ASG-GSRLGHVDQSSGGAWAGTLDQSGGGSKPRFENQTTEEGSWA-GAGGQAGGGSKVGP 1509

Query: 2114 SGQSSSYSQHGSGSGHSSGY--GQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGS----- 2166
              QSS  S   SG   S G+  G     +G S  G  H +S G    +    SG      
Sbjct: 1510 EDQSSGRSWANSGDQISGGFLVGIVDQANGGSWTGAGHPASVGPKPIFEDQVSGRGSWAD 1569

Query: 2167 --RQSSGHGRQG---SGSGHS-PSRGRHGSG-----SGHSSSHGQHGSGSGRS---SSRG 2212
               Q  G  R G     SG S    G   SG      G  ++ G  G  SG+    S  G
Sbjct: 1570 AREQVVGDSRLGLRDQSSGDSWAGTGDQASGWFCVCPGSQTNGGSWGGASGQDVGGSRPG 1629

Query: 2213 PY-ESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTG 2271
            P  +S +G     G   SGS  + A +   +G    CS+      +     +   G  TG
Sbjct: 1630 PTNQSSAGSWDSPGSQVSGSCWTGAGAVDQAGG---CSKPGFEDQAIGGGFWPGAGDQTG 1686

Query: 2272 QSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRH 2331
              S  G       QSS  G  G   GQ     R G       S G   +G+G + SSGR 
Sbjct: 1687 GGSRPGSE----DQSSGIGSWGVAGGQVLGGARPGPAD---QSSGGSWAGTG-NQSSGRS 1738

Query: 2332 GSGSG-QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSS 2390
              G G Q+      E       G +  G+GS            SG+S  G R G+ +   
Sbjct: 1739 WIGPGDQAVDCSKPEFEDQACGGGSWAGAGS----------QASGESWAGSRPGNEAIGG 1788

Query: 2391 SSYGQHGSGSRQSLGHGQ-HGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGP 2449
            S  G     +  S    +   SG  Q         G   G  +  +  GS   W+  +  
Sbjct: 1789 SRMGSEDQATGGSWARSEDQASGRFQVSFEVEANEGFWFGPGAE-AVIGSWC-WTEEKAD 1846

Query: 2450 YESG-SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG--QHGSTSGQSSSCGQHGASS 2506
              S             SR+G+ +       +   +S+    +    +   S  G    + 
Sbjct: 1847 IVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVGAEAGAG 1906

Query: 2507 GQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG 2537
             ++ +  + G+G+   +G    G+G+G  PG
Sbjct: 1907 AEAGAGAEAGAGAGAEAG-AEAGAGAGAGPG 1936



 Score = 99.0 bits (245), Expect = 6e-20
 Identities = 209/884 (23%), Positives = 304/884 (34%), Gaps = 160/884 (18%)

Query: 766  GRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASG----FGQHE 821
            G Q SG   +  +   G+ +G  +S G   +G    +S G +     QA G     GQ  
Sbjct: 1276 GEQASGGLWAGGQTSEGTWAGDKASGGAW-TGAENQASGGSWALAGNQAIGELWAAGQAS 1334

Query: 822  SGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRG 881
             GS  G    G ASG         S  G+ +  G    +  Q+S        S   +G G
Sbjct: 1335 DGSWPG----GQASGV--------SWVGEEAIGGSWTGAENQASE------GSWAGAGAG 1376

Query: 882  RHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQS 941
               S S  +    Q G GS    S     SG G         SG G  +G G ++S G  
Sbjct: 1377 NMSSVSYWAGVVDQAGGGSWAGTS---DQSGGGSKPRFEDQASGEGSWAGAGGQASGGSM 1433

Query: 942  SGYTQHGSGSGHSSSYEQ--HGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGH--- 996
             G     SG   + + +Q   GSR G   +S    S    + +  Q G GS+    +   
Sbjct: 1434 LGPEDQSSGRSWADTADQASGGSRLGHVDQS----SGGAWAGTLDQSGGGSKPRFENQTT 1489

Query: 997  ---------GQHGSGSGQSP-SPSRGRHGSGSGQSSSYG------PYRSGSGWSSSRGPY 1040
                     GQ G GS   P   S GR  + SG   S G         +G  W+ +  P 
Sbjct: 1490 EEGSWAGAGGQAGGGSKVGPEDQSSGRSWANSGDQISGGFLVGIVDQANGGSWTGAGHPA 1549

Query: 1041 ESG---------SGH------------SSGLGHRESRSGQS-SGYGQHGSS-----SGHS 1073
              G         SG              S LG R+  SG S +G G   S       G  
Sbjct: 1550 SVGPKPIFEDQVSGRGSWADAREQVVGDSRLGLRDQSSGDSWAGTGDQASGWFCVCPGSQ 1609

Query: 1074 STHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGS 1133
            +  G  G  SGQ     + G ++   SS G   S  SQ SG    G+G+    G G    
Sbjct: 1610 TNGGSWGGASGQDVGGSRPGPTN--QSSAGSWDSPGSQVSGSCWTGAGAVDQAG-GCSKP 1666

Query: 1134 GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG- 1192
            G       G    G+G  +  G       +SSG G    + GQ    ++ G     S G 
Sbjct: 1667 GFEDQAIGGGFWPGAGDQTGGGSRPGSEDQSSGIGSWGVAGGQVLGGARPGPADQSSGGS 1726

Query: 1193 -YGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSR-GRHGS 1250
              G     SG+S  G    +   S   +     G    +G G Q SG   + SR G    
Sbjct: 1727 WAGTGNQSSGRSWIGPGDQAVDCSKPEFEDQACGGGSWAGAGSQASGESWAGSRPGNEAI 1786

Query: 1251 GLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS----GH 1306
            G     S  Q   GS   S     +  SG   V  + E+  G        G G+    G 
Sbjct: 1787 GGSRMGSEDQATGGSWARSE----DQASGRFQVSFEVEANEGF-----WFGPGAEAVIGS 1837

Query: 1307 FC---------------------SQGQHGSTSGQSSTFDQEGSSTG----QSSSYGHRGS 1341
            +C                     S+ + G  +   S  + E  ++     +S    + GS
Sbjct: 1838 WCWTEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGS 1897

Query: 1342 GSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSG---RHGSGSGQS 1398
                 +G G   AG+G     G  G+ +G  +  G  G+G G  S +G     G  +   
Sbjct: 1898 CVGAEAGAGAE-AGAGAEAGAGA-GAEAGAEAGAGA-GAGPGTESGAGVWSWDGDATTVE 1954

Query: 1399 SGFGHHESS---SWQSSGCTQHGSGSGHSS-SYEQHGSRS---GQSSRGERHGSSSGSSS 1451
            S  G  E +   SW  +        S  SS   E+   RS    +S       S SG  +
Sbjct: 1955 SRLGAGEEAGVESWTLARNVGEDELSRESSPDIEEISLRSLFWAESENSNTFRSKSGKDA 2014

Query: 1452 SYGQHGSGSRQSLGH----------------GQHGSGSGQSPSPSRGRHGSGSGQSSSYS 1495
            S+ + G+G   S+                  G   +   +S   ++ +  S S     Y 
Sbjct: 2015 SF-ESGAGDNTSIKDKFEAAGGVDIGSWFCAGNENTSEDKSAPKAKAKKSSESRGIYPYM 2073

Query: 1496 PYGSGSG-------WSSSRGPYESGSSHS-SGLGHRESRSGQSS 1531
              G+G G       WS ++  ++S +S        +++R+G+ +
Sbjct: 2074 VPGAGMGSWDGAMIWSETKFAHQSEASFPVEDESRKQTRTGEKT 2117



 Score = 98.6 bits (244), Expect = 8e-20
 Identities = 178/773 (23%), Positives = 270/773 (34%), Gaps = 85/773 (10%)

Query: 378  GSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSP 437
            GS SG +  +G      R  +      S    +  R ++  G G     G++ SG   + 
Sbjct: 1231 GSWSGASDKAG----IIRSWAVACDETSVKSWAGARAENVVGIGTWARAGEQASGGLWAG 1286

Query: 438  SSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGS- 496
                 GT  G  +S G +      +SG                   GS   +G+   G  
Sbjct: 1287 GQTSEGTWAGDKASGGAWTGAENQASG-------------------GSWALAGNQAIGEL 1327

Query: 497  -RSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQS 555
              +GQ+S G   G  A   S  G+   G   +   ++   GS            +G+  S
Sbjct: 1328 WAAGQASDGSWPGGQASGVSWVGEEAIGGSWTGAENQASEGSWAGAG-------AGNMSS 1380

Query: 556  SSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGS 615
             SY           S       SG  S    ++  SG+ S  G  G +SG  S  G    
Sbjct: 1381 VSYWAGVVDQAGGGSWAGTSDQSGGGSKPRFEDQASGEGSWAGAGGQASG-GSMLGPEDQ 1439

Query: 616  TSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSY 675
            +SG+S +     A+ G    H    SG + +    Q G G     S+ R  +      S+
Sbjct: 1440 SSGRSWADTADQASGGSRLGHVDQSSGGAWAGTLDQSGGG-----SKPRFENQTTEEGSW 1494

Query: 676  GQHGSGSGWSSSNGPHGSVSGQS-SGFGHKSGSG-------QSSGYSQHGSGSSHSSGYR 727
               G  +G  S  GP    SG+S +  G +   G       Q++G S  G+G   S G +
Sbjct: 1495 AGAGGQAGGGSKVGPEDQSSGRSWANSGDQISGGFLVGIVDQANGGSWTGAGHPASVGPK 1554

Query: 728  K--HGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSG-SGHSPSRVRHGSS 784
                   SG+ S ++      G S    +  S     +G G Q SG     P    +G S
Sbjct: 1555 PIFEDQVSGRGSWADAREQVVGDSRLGLRDQSSGDSWAGTGDQASGWFCVCPGSQTNGGS 1614

Query: 785  SGHSSSHGQHGS--GTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQG 842
             G +S     GS  G +  SS G ++S   Q S  G   +G+G      G +   F  Q 
Sbjct: 1615 WGGASGQDVGGSRPGPTNQSSAGSWDSPGSQVS--GSCWTGAGAVDQAGGCSKPGFEDQA 1672

Query: 843  RHGS---TSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHG----SGSGQSPGHGQ 895
              G     +G  +  G    S  QSS  G    A     G  R G    S  G   G G 
Sbjct: 1673 IGGGFWPGAGDQTGGGSRPGSEDQSSGIGSWGVAGGQVLGGARPGPADQSSGGSWAGTGN 1732

Query: 896  RGSGSG-----------QSPSYGRHGSGSGRSSSSGRHGSG-SGQSSGFGHKSSSGQSSG 943
            + SG               P +     G G  + +G   SG S   S  G+++  G   G
Sbjct: 1733 QSSGRSWIGPGDQAVDCSKPEFEDQACGGGSWAGAGSQASGESWAGSRPGNEAIGGSRMG 1792

Query: 944  YTQHGSGSGHSSSYEQHGSR---SGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHG 1000
                 +G   + S +Q   R   S +   +E      G+ +  G     + +        
Sbjct: 1793 SEDQATGGSWARSEDQASGRFQVSFEVEANEGFWFGPGAEAVIGS-WCWTEEKADIVSRP 1851

Query: 1001 SGSGQSPSPSRGRHGSGS---GQSSSYGPYRSGSGWSSSRGPYESGS--GHSSGLGHRES 1055
                ++ + SR R G  +    +  +     SGS W  S      GS  G  +G G  E+
Sbjct: 1852 DDKDEATTASRSRAGEEAMICSRIEAENKASSGS-WIRSEEVAYMGSCVGAEAGAG-AEA 1909

Query: 1056 RSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSG 1108
             +G  +G G  G+ +G  +  G  G+  G  S  G        ++   + G+G
Sbjct: 1910 GAGAEAGAGA-GAEAGAEAGAGA-GAGPGTESGAGVWSWDGDATTVESRLGAG 1960



 Score = 98.6 bits (244), Expect = 8e-20
 Identities = 148/618 (23%), Positives = 216/618 (34%), Gaps = 61/618 (9%)

Query: 2202 GSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS 2261
            GS SG S   G   S +    V     S    + A +++  G G +   G+  S    + 
Sbjct: 1231 GSWSGASDKAGIIRSWA----VACDETSVKSWAGARAENVVGIGTWARAGEQASGGLWAG 1286

Query: 2262 TFDQEGSSTGQSSSHGQHGSGSSQSSS-----YGQQGSGSGQSPSRGRHGSGSGHSSS-- 2314
                EG+  G  +S G      +Q+S       G Q  G   +  +   GS  G  +S  
Sbjct: 1287 GQTSEGTWAGDKASGGAWTGAENQASGGSWALAGNQAIGELWAAGQASDGSWPGGQASGV 1346

Query: 2315 --YGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGS 2372
               G+   G  W+ +  +   GS   +G G+  S S+ +    Q G GS   +S +  G 
Sbjct: 1347 SWVGEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGGGSWAGTSDQSGG- 1405

Query: 2373 RSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSS 2432
              G   R E   S  GS +  G   SG    LG     SG   + +  +   GS  G   
Sbjct: 1406 --GSKPRFEDQASGEGSWAGAGGQASGG-SMLGPEDQSSGRSWADTADQASGGSRLG--- 1459

Query: 2433 SYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGST 2492
             +    SG  W+ +    +SG G      ++ +  G  +G    G  +G  S  G    +
Sbjct: 1460 -HVDQSSGGAWAGTLD--QSGGGSKPRFENQTTEEGSWAG---AGGQAGGGSKVGPEDQS 1513

Query: 2493 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG 2552
            SG+S       A+SG   S G       Q++G    G+G   S G           P + 
Sbjct: 1514 SGRS------WANSGDQISGGFLVGIVDQANGGSWTGAGHPASVG---------PKPIFE 1558

Query: 2553 RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS-SSYSQHGSG-----SGHSSGYGQH 2606
               SG G  + + +   G    S  G  + SSG S +      SG      G  +  G  
Sbjct: 1559 DQVSGRGSWADAREQVVG---DSRLGLRDQSSGDSWAGTGDQASGWFCVCPGSQTNGGSW 1615

Query: 2607 GSRSGQSSRGERHG----SSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL 2662
            G  SGQ   G R G    SS+GS    G   SGS  +       +G    P       G 
Sbjct: 1616 GGASGQDVGGSRPGPTNQSSAGSWDSPGSQVSGSCWTGAGAVDQAGGCSKPGFEDQAIGG 1675

Query: 2663 GHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ 2722
            G     G    G  R  S     S +G   V G    G        Q   GS      G 
Sbjct: 1676 GFWPGAGDQTGGGSRPGSE-DQSSGIGSWGVAGGQVLGGARPGPADQSSGGSW----AGT 1730

Query: 2723 HGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQS 2782
               +SG+S     + +       +  +  G    +G G     SG+S +  R G+ +   
Sbjct: 1731 GNQSSGRSWIGPGDQAVDCSKPEFEDQACGGGSWAGAG--SQASGESWAGSRPGNEAIGG 1788

Query: 2783 SSYGQHGSGSGQSSGYSQ 2800
            S  G     +G S   S+
Sbjct: 1789 SRMGSEDQATGGSWARSE 1806



 Score = 89.0 bits (219), Expect = 6e-17
 Identities = 147/582 (25%), Positives = 198/582 (34%), Gaps = 138/582 (23%)

Query: 2306 GSGSGHSSSYG---------QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQ 2356
            GS SG S   G            S   W+ +   +  G G  +  G   S    + G T 
Sbjct: 1231 GSWSGASDKAGIIRSWAVACDETSVKSWAGARAENVVGIGTWARAGEQASGGLWAGGQTS 1290

Query: 2357 HGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQS 2416
             G+ +G  +S        G +  G  + +S GS +  G    G   + G    GS  G  
Sbjct: 1291 EGTWAGDKAS--------GGAWTGAENQASGGSWALAGNQAIGELWAAGQASDGSWPG-- 1340

Query: 2417 PSPSRGRHGSGSGQSSSYSPYGS---GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGY 2473
                        GQ+S  S  G    G  W+ +      GS   +G G+  S S  +   
Sbjct: 1341 ------------GQASGVSWVGEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVV 1388

Query: 2474 GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSG 2533
             Q G            GS +G S                    SG      +  Q SG G
Sbjct: 1389 DQAGG-----------GSWAGTSDQ------------------SGGGSKPRFEDQASGEG 1419

Query: 2534 QSPGHGQRGSGSRQSPSYGRHGSGSGRS-SSSGQHGSGLGESSGFGHHESSSGQSSSYSQ 2592
               G G + SG       G     SGRS + +    SG    S  GH + SSG + + + 
Sbjct: 1420 SWAGAGGQASGGSM---LGPEDQSSGRSWADTADQASG---GSRLGHVDQSSGGAWAGTL 1473

Query: 2593 HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSR-----QSSGHGRQGS 2647
              SG G         S+    ++    GS +G+    GQ G GS+     QSSG     S
Sbjct: 1474 DQSGGG---------SKPRFENQTTEEGSWAGAG---GQAGGGSKVGPEDQSSGRSWANS 1521

Query: 2648 GSGQS---------PSRGRHGSGLGHSSSHGQ----HGSGSGRSSSRGPYESRLGHSSVF 2694
            G   S          + G   +G GH +S G         SGR S     E  +G S + 
Sbjct: 1522 GDQISGGFLVGIVDQANGGSWTGAGHPASVGPKPIFEDQVSGRGSWADAREQVVGDSRL- 1580

Query: 2695 GQHESGSGHSSAYSQHGSG---SGHFC-------SQGQHGSTSGQSSTFDQEG----SST 2740
            G  +  SG S A    G+G   SG FC       + G  G  SGQ     + G    SS 
Sbjct: 1581 GLRDQSSGDSWA----GTGDQASGWFCVCPGSQTNGGSWGGASGQDVGGSRPGPTNQSSA 1636

Query: 2741 GQSSSYGHRGSGS--------SQSSGYGRHG-----------AGSGQSLSHGRHGSGSGQ 2781
            G   S G + SGS         Q+ G  + G            G+G     G       Q
Sbjct: 1637 GSWDSPGSQVSGSCWTGAGAVDQAGGCSKPGFEDQAIGGGFWPGAGDQTGGGSRPGSEDQ 1696

Query: 2782 SSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGS 2823
            SS  G  G   GQ  G ++ G      G S+   G+   G S
Sbjct: 1697 SSGIGSWGVAGGQVLGGARPGPADQSSGGSWAGTGNQSSGRS 1738



 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 153/621 (24%), Positives = 223/621 (35%), Gaps = 76/621 (12%)

Query: 131  SWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSS 190
            SW+  EN +   +  G+      S+S          G   + +   S  G +     Q+S
Sbjct: 1357 SWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGGGSWAGTSDQSGGGSKPRFEDQAS 1416

Query: 191  GRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSG 250
            G G      GQ+       SG       D     SG+S   +  ++S G   G+    SG
Sbjct: 1417 GEGSWAGAGGQA-------SGGSMLGPED---QSSGRSWADTADQASGGSRLGHVDQSSG 1466

Query: 251  SGHSSGYGQHGSRSGQSSRGERHRSSSGS-SSSYGQHGSGSR-----QSLGHGRQGSGSR 304
               +    Q G   G   R E   +  GS + + GQ G GS+     QS G     SG +
Sbjct: 1467 GAWAGTLDQSG--GGSKPRFENQTTEEGSWAGAGGQAGGGSKVGPEDQSSGRSWANSGDQ 1524

Query: 305  QS-------PSHVRHGS--GSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGS 355
             S             GS  G+GH +S G           RG +     Q  G    +S  
Sbjct: 1525 ISGGFLVGIVDQANGGSWTGAGHPASVGPKPIFEDQVSGRGSWADAREQVVG----DSRL 1580

Query: 356  G---QSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSG 412
            G   QSSG S  G+G     + G      G  ++ G  G +S      GQ    SR    
Sbjct: 1581 GLRDQSSGDSWAGTG---DQASGWFCVCPGSQTNGGSWGGAS------GQDVGGSR-PGP 1630

Query: 413  RGQHSSGSGQSPGHGQRGS---GSGQ-SPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHH 468
              Q S+GS  SPG    GS   G+G    + G    GF   +  G +  G+G  +G G  
Sbjct: 1631 TNQSSAGSWDSPGSQVSGSCWTGAGAVDQAGGCSKPGFEDQAIGGGFWPGAGDQTGGGSR 1690

Query: 469  ESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSG----- 523
              S + SSG    G   G   G    G+R G + +     SS GS +  G   SG     
Sbjct: 1691 PGSEDQSSGIGSWGVAGGQVLG----GARPGPADQ-----SSGGSWAGTGNQSSGRSWIG 1741

Query: 524  --------SRQSLGHSRHGSGS-GQSPSPSRGRHESGSRQ-SSSYGPHGYGSGRSSSRGP 573
                    S+        G GS   + S + G   +GSR  + + G    GS   ++ G 
Sbjct: 1742 PGDQAVDCSKPEFEDQACGGGSWAGAGSQASGESWAGSRPGNEAIGGSRMGSEDQATGGS 1801

Query: 574  YESGSGHSSGLGHQESRSGQSSGYG-QHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQ 632
            +      +SG          + G+    G+ +   S           S    +  AT+  
Sbjct: 1802 WARSEDQASGRFQVSFEVEANEGFWFGPGAEAVIGSWCWTEEKADIVSRPDDKDEATTAS 1861

Query: 633  SSSHGQHGSGSSQSSRYGQQGSGSG-QSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPH 691
             S  G+     S+     +  SGS  +S      GS  G  +  G   +G+G  +  G  
Sbjct: 1862 RSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVGAEAGAGAE-AGAGAEAGAGA- 1919

Query: 692  GSVSGQSSGFGHKSGSGQSSG 712
            G+ +G  +G G  +G G  SG
Sbjct: 1920 GAEAGAEAGAGAGAGPGTESG 1940



 Score = 67.0 bits (162), Expect = 3e-10
 Identities = 143/668 (21%), Positives = 231/668 (34%), Gaps = 88/668 (13%)

Query: 2196 SSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQH--GSGSGHFCSQGQH 2253
            S+  Q  + S R +  G      G+S+   + E+G+G   +       S  G      ++
Sbjct: 999  SAQPQVVANSQRETLPGARNKVKGNSNAISKAEAGAGIMGSVQVQVVASFQGEVLPGAKN 1058

Query: 2254 GSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSG--H 2311
                  ++    E  +    S+  Q  + S   +  G +    G + +  + G+G+G  H
Sbjct: 1059 KVRGNSNAVPKAEAGADTVGSAQPQAVANSQSETLLGARNKVKGNTIAVPKAGTGAGTRH 1118

Query: 2312 SS-------SYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHS 2364
            S+       S G+   G+   S S      + +   +   E+ +  +S  ++ GSG+   
Sbjct: 1119 SAQPQIVAGSQGETLPGARDKSMSTSEAEATAEDEAYAKPEAEAMPTSE-SEGGSGT--- 1174

Query: 2365 SSYEQHGSRSGQSSRGERHGSSSGSSSSYG-QHGSGSRQSLGHGQHGSGSGQSPSPSRGR 2423
                    R  Q +  + + +  G       +     R     G   +    +   +   
Sbjct: 1175 -----QACRKTQPNIHDYYWNGIGVEDWIAAERWIKFRFQTMDGDWENSVSWADDENEAS 1229

Query: 2424 HGSGSGQSSSYSPYGSGS---------GWSSSRGPYESGSGHSSGLGHRESRSGQSSGYG 2474
             GS SG S       S +          W+ +R     G G  +  G + S    + G  
Sbjct: 1230 IGSWSGASDKAGIIRSWAVACDETSVKSWAGARAENVVGIGTWARAGEQASGGLWAGGQT 1289

Query: 2475 QHGS-----SSGHSSTHGQHGSTSGQSSSCGQHGA----SSGQSSSHGQHGSGSSQSSGY 2525
              G+     +SG + T  ++ ++ G  +  G        ++GQ+S     G  +S  S  
Sbjct: 1290 SEGTWAGDKASGGAWTGAENQASGGSWALAGNQAIGELWAAGQASDGSWPGGQASGVSWV 1349

Query: 2526 GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 2585
            G +  G   +    Q   GS         G+G+G  SS   + +G+ + +G G    +S 
Sbjct: 1350 GEEAIGGSWTGAENQASEGSWA-------GAGAGNMSSVS-YWAGVVDQAGGGSWAGTSD 1401

Query: 2586 QSSSYSQ---HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGH 2642
            QS   S+       SG  S  G  G  SG S  G    SS  S +      SG  +  GH
Sbjct: 1402 QSGGGSKPRFEDQASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTADQASGGSRL-GH 1460

Query: 2643 GRQGSGSGQSPSRGRHGSGLG--HSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESG 2700
              Q SG   + +  + G G      +   + GS +G     G      G S V G  +  
Sbjct: 1461 VDQSSGGAWAGTLDQSGGGSKPRFENQTTEEGSWAGAGGQAG------GGSKV-GPEDQS 1513

Query: 2701 SGHSSAYSQHGSGSGHFCS---QGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSS 2757
            SG S A S      G       Q   GS +G            G  +S G +     Q S
Sbjct: 1514 SGRSWANSGDQISGGFLVGIVDQANGGSWTG-----------AGHPASVGPKPIFEDQVS 1562

Query: 2758 GYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGS 2817
            G G       Q +   R G                 QSSG S  G+G    G+     GS
Sbjct: 1563 GRGSWADAREQVVGDSRLGLRD--------------QSSGDSWAGTGDQASGWFCVCPGS 1608

Query: 2818 NHDGGSSG 2825
              +GGS G
Sbjct: 1609 QTNGGSWG 1616


>gi|109255251 loricrin [Homo sapiens]
          Length = 312

 Score =  117 bits (293), Expect = 2e-25
 Identities = 104/296 (35%), Positives = 116/296 (39%), Gaps = 28/296 (9%)

Query: 2516 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESS 2575
            G G    SG G  G   G   G G  GSG   S   G  G G G  SS G  G G+G   
Sbjct: 22   GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCG 81

Query: 2576 GFGHHESSSGQSSSYSQHGSGSGHSSG-YGQHGSRSGQSSRGERHGSSSGSSSHYGQHGS 2634
            G       SG S  YS  G  SG  SG +   G  SG  S G   G SSG  S     G 
Sbjct: 82   G------GSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGG--GGSSGGGSGCFSSGG 133

Query: 2635 GSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVF 2694
            G     G G   SG G    +       G  SS G  G GSG  SS G      G  SV 
Sbjct: 134  GGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGG------GGGSVC 187

Query: 2695 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF---DQEGSSTGQSSSYGHRGS 2751
            G    GSG     S  GSGSG+  SQ    ++     ++      G  +G S  +   G 
Sbjct: 188  GYSGGGSGCGGG-SSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGG 246

Query: 2752 GSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQ 2807
            G S   G G  G GSG  +S G    G G S      G G G S G    GSGSG+
Sbjct: 247  GGSSGCGGGSSGIGSGCIISGGGSVCGGGSSG-----GGGGGSSVG----GSGSGK 293



 Score =  114 bits (285), Expect = 1e-24
 Identities = 109/314 (34%), Positives = 121/314 (38%), Gaps = 27/314 (8%)

Query: 629 TSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSN 688
           TSG     G  GSG      +G  GSG G S      GS  G+S   G  G G G  SS 
Sbjct: 19  TSGGGGGGG--GSGGGGCGFFGGGGSGGGSS------GSGCGYSGGGGYSGGGCGGGSSG 70

Query: 689 GPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGL 748
           G  G   G   G     GSG S  YS  G  S   SG    G   G    S   G SSG 
Sbjct: 71  GGGGGGIGGCGG-----GSGGSVKYSGGGGSSGGGSGCFSSGG-GGSGCFSSGGGGSSGG 124

Query: 749 SSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYE 808
            S     G G     G G   SG G    +     S G  SS G  G G+ C SS G   
Sbjct: 125 GSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGG--- 181

Query: 809 SGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYG 868
            G G   G+    SG G G S  GS SG+ SSQ    ++     S G   S  G S   G
Sbjct: 182 -GGGSVCGYSGGGSGCGGG-SSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSG 239

Query: 869 QHESASHHASGRGRHGSGSGQSP-GHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSG 927
              S      G G  G G G S  G G   SG G     G  G G G SS     GSGSG
Sbjct: 240 CFSS----GGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVG---GSGSG 292

Query: 928 QSSGFGHKSSSGQS 941
           +     H++   Q+
Sbjct: 293 KGVPICHQTQQKQA 306



 Score =  112 bits (279), Expect = 7e-24
 Identities = 104/297 (35%), Positives = 114/297 (38%), Gaps = 30/297 (10%)

Query: 1106 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESS 1165
            G G    SG G  G   G   G G  GSG   S   G  G G G  SS G  G G+G   
Sbjct: 22   GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCG 81

Query: 1166 GFGHHESSSGQSSSYSQHGSGSGHSSG-YGQHGSRSGQSSRGERHGSSSGSSSHYGQHGS 1224
            G       SG S  YS  G  SG  SG +   G  SG  S G   G SSG  S     G 
Sbjct: 82   G------GSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGG--GGSSGGGSGCFSSGG 133

Query: 1225 GSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF 1284
            G     G G   SG G    +       G  SS G  G GSG  SS G      G  SV 
Sbjct: 134  GGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGG------GGGSVC 187

Query: 1285 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS-----YGHR 1339
            G    GSG     S  GSGSG+  SQ    ++     ++   G S+G   S     +   
Sbjct: 188  GYSGGGSGCGGG-SSGGSGSGYVSSQQVTQTSCAPQPSYG--GGSSGGGGSGGSGCFSSG 244

Query: 1340 GSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 1396
            G G S   G G  G GSG   S G    G G S        G G  SS G  GSG G
Sbjct: 245  GGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSS-------GGGGGGSSVGGSGSGKG 294



 Score =  110 bits (276), Expect = 2e-23
 Identities = 116/320 (36%), Positives = 122/320 (38%), Gaps = 53/320 (16%)

Query: 892  GHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSG--FGHKSSSGQSSGYTQHGS 949
            G G  GSG G    +G  GSG G S S   +  G G S G   G  S  G   G    G 
Sbjct: 23   GGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGG 82

Query: 950  GSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 1009
            GSG S  Y   G  S         G  SG  SS G  GSG   S G G  G GSG   S 
Sbjct: 83   GSGGSVKYSGGGGSS---------GGGSGCFSS-GGGGSGCFSSGGGGSSGGGSGCFSSG 132

Query: 1010 SRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSS 1069
              G  G GSG  SS      G G+S      +S  G SSG                 GSS
Sbjct: 133  GGGSSGGGSGCFSS-----GGGGFSGQAVQCQSYGGVSSG-----------------GSS 170

Query: 1070 SGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHG 1129
             G S   G   S  G  S CG  G  SG        G GSS        GSGSG      
Sbjct: 171  GGGS---GCFSSGGGGGSVCGYSGGGSG-------CGGGSS-------GGSGSGYVSSQQ 213

Query: 1130 QRGSGSRQSPSYGRHGSGSGRSSSSGQHGS-GLGESSGFGHHESSSGQSSSYSQHGS-GS 1187
               +     PSYG   SG G S  SG   S G G SSG G   S  G     S  GS   
Sbjct: 214  VTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCG 273

Query: 1188 GHSSGYGQHGSRSGQSSRGE 1207
            G SSG G  GS  G S  G+
Sbjct: 274  GGSSGGGGGGSSVGGSGSGK 293



 Score =  109 bits (273), Expect = 3e-23
 Identities = 102/303 (33%), Positives = 111/303 (36%), Gaps = 46/303 (15%)

Query: 1210 GSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSS 1269
            GS  G    +G  GSG       G  GSG G+S   G  G G G  SS G  G G G   
Sbjct: 28   GSGGGGCGFFGGGGSGG------GSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIG--- 78

Query: 1270 SRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ--EG 1327
              G      G     G   S  G S  +S  G GSG F S G  GS+ G S  F     G
Sbjct: 79   --GCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCF-SSGGGGSSGGGSGCFSSGGGG 135

Query: 1328 SSTGQSSSYGHRGSGSS----QSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSG 1383
            SS G S  +   G G S    Q   YG  G  SG     G  G GSG  SS G  GS  G
Sbjct: 136  SSGGGSGCFSSGGGGFSGQAVQCQSYG--GVSSG-----GSSGGGSGCFSSGGGGGSVCG 188

Query: 1384 WSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERH 1443
            +S      G GS   SG G+  S     + C    S  G SS                  
Sbjct: 189  YSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSG----------------- 231

Query: 1444 GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSG----QSPSPSRGRHGSGSGQSSSYSPYGS 1499
            G  SG S  +   G G     G G  G GSG       S   G    G G  SS    GS
Sbjct: 232  GGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGS 291

Query: 1500 GSG 1502
            G G
Sbjct: 292  GKG 294



 Score =  108 bits (271), Expect = 6e-23
 Identities = 121/335 (36%), Positives = 129/335 (38%), Gaps = 61/335 (18%)

Query: 1345 QSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 1404
            ++SG G  G GSG        G GSG  SS    GSG G+S   G  G G G  S  G  
Sbjct: 18   KTSGGGGGGGGSGGGGCGFFGGGGSGGGSS----GSGCGYSGGGGYSGGGCGGGSSGG-- 71

Query: 1405 ESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSL 1464
                    GC   G GSG S  Y   G            GSS G S  +   G GS    
Sbjct: 72   -GGGGGIGGC---GGGSGGSVKYSGGG------------GSSGGGSGCFSSGGGGS---- 111

Query: 1465 GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRE 1524
              G   SG G S     G   SG G SS     G GSG  SS G   SG +        +
Sbjct: 112  --GCFSSGGGGSSGGGSGCFSSGGGGSS-----GGGSGCFSSGGGGFSGQAVQC-----Q 159

Query: 1525 SRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG 1584
            S  G SSG    GSS G S   G   S  G  S CG  G  SG        G GSS    
Sbjct: 160  SYGGVSSG----GSSGGGS---GCFSSGGGGGSVCGYSGGGSG-------CGGGSS---- 201

Query: 1585 YGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGS-GLGESSGFGHHESS 1643
                GSGSG         +     PSYG   SG G S  SG   S G G SSG G   S 
Sbjct: 202  ---GGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSG 258

Query: 1644 SGQSSSYSQHGS-GSGHSSGYGQHGSRSGQSSRGE 1677
             G     S  GS   G SSG G  GS  G S  G+
Sbjct: 259  IGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGK 293



 Score =  108 bits (270), Expect = 8e-23
 Identities = 105/284 (36%), Positives = 113/284 (39%), Gaps = 16/284 (5%)

Query: 2405 GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSR-GPYESGSGHSSGLGHR 2463
            G G  G GSG       G  GSG G S S   Y  G G+S    G   SG G   G+G  
Sbjct: 21   GGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGC 80

Query: 2464 ESRSGQSSGY-GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQS 2522
               SG S  Y G  GSS G S      G  SG  SS G  G SSG        GSG   S
Sbjct: 81   GGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGG--GGSSG-------GGSGCFSS 131

Query: 2523 SGYGRQGSGSG-QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHE 2581
             G G  G GSG  S G G     + Q  SYG   SG      SG   SG G  S  G+  
Sbjct: 132  GGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSG 191

Query: 2582 SSSGQSSSYSQHGSGSGH-SSGYGQHGSRSGQSS--RGERHGSSSGSSSHYGQHGSGSRQ 2638
              SG     S  GSGSG+ SS      S + Q S   G   G  SG S  +   G G   
Sbjct: 192  GGSGCGGG-SSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSS 250

Query: 2639 SSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRG 2682
              G G  G GSG   S G    G G S   G   S  G  S +G
Sbjct: 251  GCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKG 294



 Score =  108 bits (270), Expect = 8e-23
 Identities = 112/302 (37%), Positives = 117/302 (38%), Gaps = 38/302 (12%)

Query: 191 GRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQS-SGFSQHKSSSGQSSGYSQHGS 249
           G G  GSG G    +G  GSG G S S   +  G G S  G     S  G   G    G 
Sbjct: 23  GGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGG 82

Query: 250 GSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSR--QSP 307
           GSG S  Y   G  SG           SG  SS G  GSG   S G G  G GS    S 
Sbjct: 83  GSGGSVKYSGGGGSSG---------GGSGCFSS-GGGGSGCFSSGGGGSSGGGSGCFSSG 132

Query: 308 SHVRHGSGSGHSSSHGQHGSGSSYS-YSRGHYESGSGQTSGFGQHESGSGQSS--GYSKH 364
                G GSG  SS G   SG +    S G   SG     G G   SG G  S  GYS  
Sbjct: 133 GGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGG 192

Query: 365 GSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSP 424
           GSG G  SS    GS SG  SS     +S     SYG   S    S G G  SSG     
Sbjct: 193 GSGCGGGSS---GGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGG---- 245

Query: 425 GHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSG 484
           G G  G G G S      G G G   S G  V G G S G G          G +  GSG
Sbjct: 246 GGGSSGCGGGSS------GIGSGCIISGGGSVCGGGSSGGGG---------GGSSVGGSG 290

Query: 485 SG 486
           SG
Sbjct: 291 SG 292



 Score =  108 bits (269), Expect = 1e-22
 Identities = 104/284 (36%), Positives = 112/284 (39%), Gaps = 16/284 (5%)

Query: 1935 GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSR-GPYESGSGHSSGLGHR 1993
            G G  G GSG       G  GSG G S S   Y  G G+S    G   SG G   G+G  
Sbjct: 21   GGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGC 80

Query: 1994 ESRSGQSSGY-GQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQS 2052
               SG S  Y G  GSS G S      G  SG  SS G  G SSG        GSG   S
Sbjct: 81   GGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGG--GGSSG-------GGSGCFSS 131

Query: 2053 SGYGRQGSGSG-QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHE 2111
             G G  G GSG  S G G     + Q  SYG   SG      SG    G G  S  G+  
Sbjct: 132  GGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSG 191

Query: 2112 SSSGQSSSYSQHGSGSGH-SSGYGQHGSRSGQSS--RGERHGSSSGSSSRYGQHGSGSRQ 2168
              SG     S  GSGSG+ SS      S + Q S   G   G  SG S  +   G G   
Sbjct: 192  GGSGCGGG-SSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSS 250

Query: 2169 SSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRG 2212
              G G  G GSG   S G    G G S   G   S  G  S +G
Sbjct: 251  GCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKG 294



 Score =  107 bits (267), Expect = 2e-22
 Identities = 105/284 (36%), Positives = 113/284 (39%), Gaps = 16/284 (5%)

Query: 995  GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSR-GPYESGSGHSSGLGHR 1053
            G G  G GSG       G  GSG G S S   Y  G G+S    G   SG G   G+G  
Sbjct: 21   GGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGC 80

Query: 1054 ESRSGQSSGY-GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQS 1112
               SG S  Y G  GSS G S      G  SG  SS G  G SSG        GSG   S
Sbjct: 81   GGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGG--GGSSG-------GGSGCFSS 131

Query: 1113 SGYGRQGSGSG-QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHE 1171
             G G  G GSG  S G G     + Q  SYG   SG      SG   SG G  S  G+  
Sbjct: 132  GGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSG 191

Query: 1172 SSSGQSSSYSQHGSGSGH-SSGYGQHGSRSGQSS--RGERHGSSSGSSSHYGQHGSGSRQ 1228
              SG     S  GSGSG+ SS      S + Q S   G   G  SG S  +   G G   
Sbjct: 192  GGSGCGGG-SSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSS 250

Query: 1229 SSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRG 1272
              G G  G GSG   S G    G G S   G   S  G  S +G
Sbjct: 251  GCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKG 294



 Score =  107 bits (266), Expect = 2e-22
 Identities = 118/315 (37%), Positives = 125/315 (39%), Gaps = 58/315 (18%)

Query: 2320 SGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 2379
            SG G     G  GSG G    FG               G GSG  SS    GS  G S  
Sbjct: 20   SGGG----GGGGGSGGGGCGFFG---------------GGGSGGGSS----GSGCGYSGG 56

Query: 2380 GERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGS 2439
            G   G   G  SS G  G G       G  G GSG S   S G   SG G S  +S  G 
Sbjct: 57   GGYSGGGCGGGSSGGGGGGGI------GGCGGGSGGSVKYSGGGGSSGGG-SGCFSSGGG 109

Query: 2440 GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 2499
            GSG       + SG G SSG G   S    S G G  G  SG  S+ G  G  SGQ+  C
Sbjct: 110  GSGC------FSSGGGGSSGGG---SGCFSSGGGGSSGGGSGCFSSGG--GGFSGQAVQC 158

Query: 2500 GQH-GASSGQSSSHG----QHGSGSSQSSGY--GRQGSGSGQSPGHGQRGSGSRQ----- 2547
              + G SSG SS  G      G G     GY  G  G G G S G G     S+Q     
Sbjct: 159  QSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTS 218

Query: 2548 ---SPSYGRHGSGSGRSSSSGQHGS-GLGESSGFGHHESSSGQSSSYSQHGS-GSGHSSG 2602
                PSYG   SG G S  SG   S G G SSG G   S  G     S  GS   G SSG
Sbjct: 219  CAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSG 278

Query: 2603 YGQHGSRSGQSSRGE 2617
             G  GS  G S  G+
Sbjct: 279  GGGGGSSVGGSGSGK 293



 Score =  106 bits (265), Expect = 3e-22
 Identities = 107/302 (35%), Positives = 115/302 (38%), Gaps = 24/302 (7%)

Query: 1693 GSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSS 1752
            G G    SG G  G   G     G  GSG G+S   G  G G G  SS G      G   
Sbjct: 22   GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGG------GGGG 75

Query: 1753 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSG 1812
              G    GSG S  YS  G  SG     G   S  G S  F    SS G  SS G  GSG
Sbjct: 76   GIGGCGGGSGGSVKYSGGGGSSGG--GSGCFSSGGGGSGCF----SSGGGGSSGG--GSG 127

Query: 1813 SSQSSSYGQQGSGSGQSPSRGRHGSGSG-HSSSYGQHGSGSGWSSSSGRHGSGSGQSSGF 1871
               S   G  G GSG   S G   SG      SYG   SG      SG   SG G  S  
Sbjct: 128  CFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVC 187

Query: 1872 GHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSR 1931
            G+    S    G +  GSGSG+ SS +       Q+S   Q     GSS   G  GSG  
Sbjct: 188  GYSGGGSGCGGG-SSGGSGSGYVSSQQVT-----QTSCAPQPSYGGGSSGGGGSGGSGCF 241

Query: 1932 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLG 1991
             S G G      G S     G   SG G     G  G G G SS  G   SGSG    + 
Sbjct: 242  SSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGG---SGSGKGVPIC 298

Query: 1992 HR 1993
            H+
Sbjct: 299  HQ 300



 Score =  106 bits (265), Expect = 3e-22
 Identities = 110/315 (34%), Positives = 118/315 (37%), Gaps = 45/315 (14%)

Query: 1223 GSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSS 1282
            G G    SG G  G   G     G  GSG G+S   G  G G G  SS G      G   
Sbjct: 22   GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGG------GGGG 75

Query: 1283 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSG 1342
              G    GSG S  YS  G            GS+ G S  F   G  +G  SS    G G
Sbjct: 76   GIGGCGGGSGGSVKYSGGG------------GSSGGGSGCFSSGGGGSGCFSS----GGG 119

Query: 1343 SSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFG 1402
             S   G G   +G G     G  G GSG  SS      G G+S  + +  S  G SSG  
Sbjct: 120  GSSGGGSGCFSSGGG-----GSSGGGSGCFSS-----GGGGFSGQAVQCQSYGGVSSG-- 167

Query: 1403 HHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSG--SSSSYGQHGSGS 1460
                SS   SGC   G G G    Y   GS  G  S G   GS SG  SS    Q     
Sbjct: 168  ---GSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSG---GSGSGYVSSQQVTQTSCAP 221

Query: 1461 RQSLGHGQH-GSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSG 1519
            + S G G   G GSG S   S G  G  SG     S  G GSG   S G    G   S G
Sbjct: 222  QPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSS--GIGSGCIISGGGSVCGGGSSGG 279

Query: 1520 LGHRESRSGQSSGYG 1534
             G   S  G  SG G
Sbjct: 280  GGGGSSVGGSGSGKG 294



 Score =  106 bits (265), Expect = 3e-22
 Identities = 115/328 (35%), Positives = 124/328 (37%), Gaps = 66/328 (20%)

Query: 1340 GSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSS 1399
            G G    SG G  G   G     G  GSG G+S   G  G G G  SS G  G G G   
Sbjct: 22   GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIG--- 78

Query: 1400 GFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSG 1459
                         GC   G GSG S  Y   G            GSS G S  +   G G
Sbjct: 79   -------------GC---GGGSGGSVKYSGGG------------GSSGGGSGCFSSGGGG 110

Query: 1460 SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSG 1519
            S      G   SG G S     G   SG G SS     G GSG  SS G   SG +    
Sbjct: 111  S------GCFSSGGGGSSGGGSGCFSSGGGGSS-----GGGSGCFSSGGGGFSGQAVQC- 158

Query: 1520 LGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS---SSCGQHGASSGQSSSHGQHG 1576
                +S  G SSG G  G  SG  S+ G  GS  G S   S CG  G SSG S S     
Sbjct: 159  ----QSYGGVSSG-GSSGGGSGCFSSGGGGGSVCGYSGGGSGCG--GGSSGGSGSGYVSS 211

Query: 1577 SGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGES-- 1634
               +Q+S   +   G G S G G  GSG   S        G G SS  G   SG+G    
Sbjct: 212  QQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSS-------GGGGGSSGCGGGSSGIGSGCI 264

Query: 1635 -SGFGH---HESSSGQSSSYSQHGSGSG 1658
             SG G      SS G     S  GSGSG
Sbjct: 265  ISGGGSVCGGGSSGGGGGGSSVGGSGSG 292



 Score =  106 bits (265), Expect = 3e-22
 Identities = 111/309 (35%), Positives = 120/309 (38%), Gaps = 39/309 (12%)

Query: 1012 GRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSG-LGHRESRSGQSSGYGQHGSSS 1070
            G  GSG G    +G   SG G S S   Y  G G+S G  G   S  G   G G  G  S
Sbjct: 25   GGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGS 84

Query: 1071 GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSG--QSPGH 1128
            G S  +   G +SG  S C           S G  GSG   S G G  G GSG   S G 
Sbjct: 85   GGSVKYSGGGGSSGGGSGC----------FSSGGGGSGCFSSGGGGSSGGGSGCFSSGGG 134

Query: 1129 GQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSG 1188
            G  G GS    S G  G  SG++     +G   G SSG      SSG  S     G G G
Sbjct: 135  GSSGGGSGCFSSGG--GGFSGQAVQCQSYG---GVSSG-----GSSGGGSGCFSSGGGGG 184

Query: 1189 HSSGYGQHGSRSGQSSRGERHGSSSG--SSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRG 1246
               GY   GS  G  S G   GS SG  SS    Q     + S G G  G G       G
Sbjct: 185  SVCGYSGGGSGCGGGSSG---GSGSGYVSSQQVTQTSCAPQPSYGGGSSGGG-------G 234

Query: 1247 RHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGH 1306
              GSG   S   G      G SS  G     SG  SV G   SG G   + S  GSGSG 
Sbjct: 235  SGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGS-SVGGSGSGK 293

Query: 1307 ---FCSQGQ 1312
                C Q Q
Sbjct: 294  GVPICHQTQ 302



 Score =  105 bits (263), Expect = 5e-22
 Identities = 110/317 (34%), Positives = 120/317 (37%), Gaps = 39/317 (12%)

Query: 2050 SQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESS---- 2105
            +   G G  GSG G     G  GSG       G  GSG G S   G  G G G  S    
Sbjct: 19   TSGGGGGGGGSGGGGCGFFGGGGSGG------GSSGSGCGYSGGGGYSGGGCGGGSSGGG 72

Query: 2106 ---GFGHHESSSGQSSSYSQHGSGSGHSSG-YGQHGSRSGQSSRGERHGSSSGSSSRYGQ 2161
               G G     SG S  YS  G  SG  SG +   G  SG  S G   G SSG       
Sbjct: 73   GGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSG--GGGSSGG------ 124

Query: 2162 HGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSG-HSSSHGQHGSGSGRSSSRGPYESRSGH 2220
             GSG   S G G  G GSG   S G   SG      S+G   SG       G + S  G 
Sbjct: 125  -GSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGG 183

Query: 2221 SSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHG 2280
             SV G    GSG     S  GSGSG+  SQ        Q+S   Q     G S   G  G
Sbjct: 184  GSVCGYSGGGSGCGGG-SSGGSGSGYVSSQ-----QVTQTSCAPQPSYGGGSSGGGGSGG 237

Query: 2281 SGS-SQSSSYGQQGSGSGQSP-SRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQS 2338
            SG  S     G  G G G S    G   SG G     G  G G G SS     GSGSG+ 
Sbjct: 238  SGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVG---GSGSGKG 294

Query: 2339 SGFGHH----ESSSWQS 2351
                H     ++ +W S
Sbjct: 295  VPICHQTQQKQAPTWPS 311



 Score =  105 bits (263), Expect = 5e-22
 Identities = 117/315 (37%), Positives = 124/315 (39%), Gaps = 58/315 (18%)

Query: 1850 SGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 1909
            SG G     G  GSG G    FG               G GSG  SS    GS  G S  
Sbjct: 20   SGGG----GGGGGSGGGGCGFFG---------------GGGSGGGSS----GSGCGYSGG 56

Query: 1910 GEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGS 1969
            G   G   G  SS G  G G       G  G GSG S   S G   SG G     G + S
Sbjct: 57   GGYSGGGCGGGSSGGGGGGGI------GGCGGGSGGSVKYSGGGGSSGGGS----GCFSS 106

Query: 1970 GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSC 2029
            G G S   G + SG G SSG G   S    S G G  G  SG  S+ G  G  SGQ+  C
Sbjct: 107  GGGGS---GCFSSGGGGSSGGG---SGCFSSGGGGSSGGGSGCFSSGG--GGFSGQAVQC 158

Query: 2030 GQHGA-SSGQSSSHGQ----HGSGSSQSSGY--GRQGSGSGQSPGHGQRGSGSRQ----- 2077
              +G  SSG SS  G      G G     GY  G  G G G S G G     S+Q     
Sbjct: 159  QSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTS 218

Query: 2078 ---SPSYGRHGSGSGRSSSSGQHGP-GLGESSGFGHHESSSGQSSSYSQHGS-GSGHSSG 2132
                PSYG   SG G S  SG     G G SSG G   S  G     S  GS   G SSG
Sbjct: 219  CAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSG 278

Query: 2133 YGQHGSRSGQSSRGE 2147
             G  GS  G S  G+
Sbjct: 279  GGGGGSSVGGSGSGK 293



 Score =  105 bits (263), Expect = 5e-22
 Identities = 106/320 (33%), Positives = 115/320 (35%), Gaps = 47/320 (14%)

Query: 2150 GSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSS 2209
            G   G  S  G  G      SG G  GSG G+S   G  G G G  SS G  G G G   
Sbjct: 22   GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIG--- 78

Query: 2210 SRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEG-- 2267
              G      G     G   S  G S  +S  G GSG F S G  GS+ G S  F   G  
Sbjct: 79   --GCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCF-SSGGGGSSGGGSGCFSSGGGG 135

Query: 2268 SSTGQSSSHGQHGSGSS----QSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSG 2323
            SS G S      G G S    Q  SYG   SG       G  G GSG  SS G  GS  G
Sbjct: 136  SSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSG-------GSSGGGSGCFSSGGGGGSVCG 188

Query: 2324 WSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERH 2383
            +S      G GS   SG G+  S     +      S  G SS                  
Sbjct: 189  YSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSG----------------- 231

Query: 2384 GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGW 2443
            G  SG S  +   G G     G G  G GSG   S      G GS         G G G 
Sbjct: 232  GGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSS--------GGGGGG 283

Query: 2444 SSSRGPYESGSGHSSGLGHR 2463
            SS  G   SGSG    + H+
Sbjct: 284  SSVGG---SGSGKGVPICHQ 300



 Score =  105 bits (263), Expect = 5e-22
 Identities = 109/298 (36%), Positives = 118/298 (39%), Gaps = 30/298 (10%)

Query: 1807 GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 1866
            G  GSG      +G  GSG G S      GSG G+S   G  G G G  SS G  G G G
Sbjct: 25   GGGGSGGGGCGFFGGGGSGGGSS------GSGCGYSGGGGYSGGGCGGGSSGGGGGGGIG 78

Query: 1867 QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQH 1926
               G G   S  +   G +  G GSG  SS    G  SG  S G   G SSG        
Sbjct: 79   GCGG-GSGGSVKYSGGGGSS-GGGSGCFSS---GGGGSGCFSSG--GGGSSGG------- 124

Query: 1927 GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGH 1986
            GSG   S G G  G GSG   S   G  G  + Q  SYG   SG       G + SG G 
Sbjct: 125  GSGCFSSGGGGSSGGGSGCFSSGGGGFSGQ-AVQCQSYGGVSSGGSSGGGSGCFSSGGGG 183

Query: 1987 SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHG 2046
             S  G+    SG  SG G  G SSG S +         Q+S   Q     G S   G  G
Sbjct: 184  GSVCGY----SGGGSGCG--GGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGG 237

Query: 2047 SGS-SQSSGYGRQGSGSGQSP-GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLG 2102
            SG  S   G G  G G G S  G G   SG       G  G G G SS  G  G G G
Sbjct: 238  SGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGS-GSGKG 294



 Score =  105 bits (262), Expect = 6e-22
 Identities = 106/308 (34%), Positives = 112/308 (36%), Gaps = 35/308 (11%)

Query: 761  QSSGHGRQGSGSGHSPSRVRHGSSSGHSSSH---GQHGSGTSCSSSCGHYESGSGQASGF 817
            ++SG G  G GSG        G  SG  SS    G  G G      CG   SG G   G 
Sbjct: 18   KTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGI 77

Query: 818  GQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHA 877
            G    GSG      G   G  SS G  G  S     SG   S  G SS  G   S    +
Sbjct: 78   GGCGGGSGGSVKYSG---GGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGG---SGCFSS 131

Query: 878  SGRGRHGSGSGQSPGHGQRGSGSG-QSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKS 936
             G G  G GSG     G   SG   Q  SYG   SG      SG   SG G         
Sbjct: 132  GGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGG--------- 182

Query: 937  SSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGH 996
              G   GY+  GSG G  SS    GS SG  S  +   +S     SYG   SG   S G 
Sbjct: 183  -GGSVCGYSGGGSGCGGGSS---GGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGS 238

Query: 997  GQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESR 1056
            G   SG G       G  G G G S        GSG   S G    G G S G G   S 
Sbjct: 239  GCFSSGGGG------GSSGCGGGSSG------IGSGCIISGGGSVCGGGSSGGGGGGSSV 286

Query: 1057 SGQSSGYG 1064
             G  SG G
Sbjct: 287  GGSGSGKG 294



 Score =  105 bits (262), Expect = 6e-22
 Identities = 111/319 (34%), Positives = 117/319 (36%), Gaps = 53/319 (16%)

Query: 2163 GSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSS 2222
            G G    SG G  G   G     G  GSG G+S   G  G G G  SS G      G   
Sbjct: 22   GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGG------GGGG 75

Query: 2223 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSG 2282
              G    GSG S  YS  G            GS+ G S  F   G  +G  SS G   SG
Sbjct: 76   GIGGCGGGSGGSVKYSGGG------------GSSGGGSGCFSSGGGGSGCFSSGGGGSSG 123

Query: 2283 SSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGS-------GWSSSSGRHGSGS 2335
                      GSG   S   G  G GSG  SS G   SG        G  SS G  G GS
Sbjct: 124  G---------GSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGS 174

Query: 2336 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQ 2395
            G  S  G          GY+  GSG G  SS    GS SG  S  +   +S     SYG 
Sbjct: 175  GCFSSGG----GGGSVCGYSGGGSGCGGGSS---GGSGSGYVSSQQVTQTSCAPQPSYGG 227

Query: 2396 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSG 2455
              SG   S G G   SG G       G  G G G S      G GSG   S G    G G
Sbjct: 228  GSSGGGGSGGSGCFSSGGG------GGSSGCGGGSS------GIGSGCIISGGGSVCGGG 275

Query: 2456 HSSGLGHRESRSGQSSGYG 2474
             S G G   S  G  SG G
Sbjct: 276  SSGGGGGGSSVGGSGSGKG 294



 Score =  105 bits (262), Expect = 6e-22
 Identities = 107/310 (34%), Positives = 126/310 (40%), Gaps = 34/310 (10%)

Query: 1311 GQHGSTSGQSSTFDQEGSSTGQSSS-YGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGS 1369
            G  GS  G    F   GS  G S S  G+ G G     G G   +G G     G  G GS
Sbjct: 25   GGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGS 84

Query: 1370 GHSSSY----GQHGSGSGWSSS----SGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGS 1421
            G S  Y    G  G GSG  SS    SG   SG G SSG G   S  + S G    G GS
Sbjct: 85   GGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGG---SGCFSSGGGGSSGGGS 141

Query: 1422 GHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR 1481
            G  SS    G  SGQ+ + + +G  S   SS G  GSG   S      G G G     S 
Sbjct: 142  GCFSS--GGGGFSGQAVQCQSYGGVSSGGSSGG--GSGCFSS------GGGGGSVCGYSG 191

Query: 1482 GRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSG 1541
            G  G G G S      GSGSG+ SS+   ++  +     G   S  G S G G   S  G
Sbjct: 192  GGSGCGGGSSG-----GSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGG 246

Query: 1542 HSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQR 1601
              S+ G  G +SG  S C     S G S   G    G    S  G  GSG G    H  +
Sbjct: 247  GGSS-GCGGGSSGIGSGC---IISGGGSVCGGGSSGGGGGGSSVGGSGSGKGVPICHQTQ 302

Query: 1602 GSGSRQSPSY 1611
                +Q+P++
Sbjct: 303  ---QKQAPTW 309



 Score =  105 bits (262), Expect = 6e-22
 Identities = 109/298 (36%), Positives = 118/298 (39%), Gaps = 30/298 (10%)

Query: 2277 GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 2336
            G  GSG      +G  GSG G S      GSG G+S   G  G G G  SS G  G G G
Sbjct: 25   GGGGSGGGGCGFFGGGGSGGGSS------GSGCGYSGGGGYSGGGCGGGSSGGGGGGGIG 78

Query: 2337 QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQH 2396
               G G   S  +   G +  G GSG  SS    G  SG  S G   G SSG        
Sbjct: 79   GCGG-GSGGSVKYSGGGGSS-GGGSGCFSS---GGGGSGCFSSG--GGGSSGG------- 124

Query: 2397 GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGH 2456
            GSG   S G G  G GSG   S   G  G  + Q  SY    SG       G + SG G 
Sbjct: 125  GSGCFSSGGGGSSGGGSGCFSSGGGGFSGQ-AVQCQSYGGVSSGGSSGGGSGCFSSGGGG 183

Query: 2457 SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHG 2516
             S  G+    SG  SG G  G SSG S +         Q+S   Q     G S   G  G
Sbjct: 184  GSVCGY----SGGGSGCG--GGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGG 237

Query: 2517 SGS-SQSSGYGRQGSGSGQSP-GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLG 2572
            SG  S   G G  G G G S  G G   SG       G  G G G SS  G  GSG G
Sbjct: 238  SGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGS-GSGKG 294



 Score =  105 bits (261), Expect = 8e-22
 Identities = 107/303 (35%), Positives = 117/303 (38%), Gaps = 42/303 (13%)

Query: 2306 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 2365
            G G G  S  G  G   G  S  G  GSG G S G G+              G G G   
Sbjct: 22   GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYS-------------GGGCG--- 65

Query: 2366 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 2425
                 G  SG    G   G   GS  S    G G     G G   SG G S   S G  G
Sbjct: 66   -----GGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGG 120

Query: 2426 SGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHR-ESRSGQSSGYGQHGSSSGHSS 2484
            S  G S  +S  G GS    S G + SG G  SG   + +S  G SSG G  G  SG  S
Sbjct: 121  SSGGGSGCFSSGGGGSSGGGS-GCFSSGGGGFSGQAVQCQSYGGVSSG-GSSGGGSGCFS 178

Query: 2485 THGQHGSTSGQS---SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQR 2541
            + G  GS  G S   S CG  G SSG S S        +Q+S   +   G G S G G  
Sbjct: 179  SGGGGGSVCGYSGGGSGCG--GGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSG 236

Query: 2542 GSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGES---SGFGH---HESSSGQSSSYSQHGS 2595
            GSG   S        G G SS  G   SG+G     SG G      SS G     S  GS
Sbjct: 237  GSGCFSS-------GGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGS 289

Query: 2596 GSG 2598
            GSG
Sbjct: 290  GSG 292



 Score =  105 bits (261), Expect = 8e-22
 Identities = 105/302 (34%), Positives = 115/302 (38%), Gaps = 38/302 (12%)

Query: 2067 GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSG 2126
            G G  GSG      +G  GSG G S      G G G S G G+     G  S      SG
Sbjct: 23   GGGGGGSGGGGCGFFGGGGSGGGSS------GSGCGYSGGGGYSGGGCGGGS------SG 70

Query: 2127 SGHSSGYGQHGSRSGQSSRGERHGSSSGSSS---RYGQHGSGSRQSSGHGRQGSGSGHSP 2183
             G   G G  G  SG S +    G SSG  S     G  GSG   S G G  G GSG   
Sbjct: 71   GGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFS 130

Query: 2184 SRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSG 2243
            S G   SG G     G   SG G  S +       G  S  G    GSG  S+    G G
Sbjct: 131  SGGGGSSGGG----SGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSS----GGG 182

Query: 2244 SGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRG 2303
             G  C     GS  G  S+    GS +G  SS     +  +   SYG   SG G S   G
Sbjct: 183  GGSVCGYSGGGSGCGGGSS---GGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSG 239

Query: 2304 RHGSGSGHSSS---YGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSG 2360
               SG G  SS    G  G GSG   S G    G G S G G          G +  GSG
Sbjct: 240  CFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGG---------GGSSVGGSG 290

Query: 2361 SG 2362
            SG
Sbjct: 291  SG 292



 Score =  104 bits (260), Expect = 1e-21
 Identities = 98/289 (33%), Positives = 107/289 (37%), Gaps = 27/289 (9%)

Query: 1576 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESS 1635
            G G    SG G  G   G   G G  GSG   S   G  G G G  SS G  G G+G   
Sbjct: 22   GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCG 81

Query: 1636 GFGHHESSSGQSSSYSQHGSGSGHSSG-YGQHGSRSGQSSRGERHGSSSRSSSRYGQHGS 1694
            G       SG S  YS  G  SG  SG +   G  SG  S G   G SS   S     G 
Sbjct: 82   G------GSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGG--GGSSGGGSGCFSSGG 133

Query: 1695 GSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF 1754
            G     G G   SG G    +       G  SS G  G GSG  SS G      G  SV 
Sbjct: 134  GGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGG------GGGSVC 187

Query: 1755 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF---DQEGSSTGQSSSHGQHGS 1811
            G    GSG     S  GSGSG+  SQ    ++     ++      G  +G S      G 
Sbjct: 188  GYSGGGSGCGGG-SSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGG 246

Query: 1812 GSSQSSSYGQQG-------SGSGQSPSRGRHGSGSGHSSSYGQHGSGSG 1853
            G S     G  G       SG G     G  G G G  SS G  GSG G
Sbjct: 247  GGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGG-GSSVGGSGSGKG 294



 Score =  104 bits (260), Expect = 1e-21
 Identities = 107/303 (35%), Positives = 115/303 (37%), Gaps = 40/303 (13%)

Query: 1127 GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG 1186
            G G  GSG      +G  GSG G S      GSG G S G G+     G  S      SG
Sbjct: 23   GGGGGGSGGGGCGFFGGGGSGGGSS------GSGCGYSGGGGYSGGGCGGGS------SG 70

Query: 1187 SGHSSGYGQHGSRSGQSSRGERHGSSSGSSS---HYGQHGSGSRQSSGHGRQGSGSG--H 1241
             G   G G  G  SG S +    G SSG  S     G  GSG   S G G  G GSG   
Sbjct: 71   GGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFS 130

Query: 1242 SPSRGRHGSGLGHSSSHGQHGSGSG-RSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQH 1300
            S   G  G G G  SS G   SG   +  S G   S        G   SG G  S     
Sbjct: 131  SGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYS 190

Query: 1301 GSGSGHFCSQGQH-GSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQS 1359
            G GSG  C  G   GS SG  S+     +S     SYG   SG   S G G   +G G  
Sbjct: 191  GGGSG--CGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGG-- 246

Query: 1360 PSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGS 1419
               G  G G G S      G GSG   S G    G G S G G          G +  GS
Sbjct: 247  --GGSSGCGGGSS------GIGSGCIISGGGSVCGGGSSGGGG---------GGSSVGGS 289

Query: 1420 GSG 1422
            GSG
Sbjct: 290  GSG 292



 Score =  103 bits (258), Expect = 2e-21
 Identities = 116/311 (37%), Positives = 124/311 (39%), Gaps = 43/311 (13%)

Query: 1952 GRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG 2011
            G  GSG G    +G  GSG G S S   Y  G G+S G            G G  G   G
Sbjct: 25   GGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGG----------GCGGGSSGGGGG 74

Query: 2012 HSSTHGQHGSASGQSSSCGQHGASSGQSS---SHGQHGSGSSQSSGYGRQGSGSG--QSP 2066
                 G  G  SG S      G SSG  S   S G  GSG   S G G  G GSG   S 
Sbjct: 75   GGI--GGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSG 132

Query: 2067 GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSG 2126
            G G  G GS    S G  G  SG++     +G   G SSG      SSG  S     G G
Sbjct: 133  GGGSSGGGSGCFSSGG--GGFSGQAVQCQSYG---GVSSG-----GSSGGGSGCFSSGGG 182

Query: 2127 SGHSSGYGQHGSRSGQSSRGERHGSSSG--SSSRYGQHGSGSRQSSGHGRQGSGSGHSPS 2184
             G   GY   GS  G  S G   GS SG  SS +  Q     + S G G   SG G S  
Sbjct: 183  GGSVCGYSGGGSGCGGGSSG---GSGSGYVSSQQVTQTSCAPQPSYGGG--SSGGGGSGG 237

Query: 2185 RGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS 2244
             G   SG G  SS    G G G SS  G     SG  SV G   SG G   + S  GSGS
Sbjct: 238  SGCFSSGGGGGSS----GCGGG-SSGIGSGCIISGGGSVCGGGSSGGGGGGS-SVGGSGS 291

Query: 2245 GH---FCSQGQ 2252
            G     C Q Q
Sbjct: 292  GKGVPICHQTQ 302



 Score =  103 bits (257), Expect = 2e-21
 Identities = 99/296 (33%), Positives = 107/296 (36%), Gaps = 28/296 (9%)

Query: 2046 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESS 2105
            G G    SG G  G   G   G G  GSG   S   G  G G G  SS G  G G+G   
Sbjct: 22   GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCG 81

Query: 2106 GFGHHESSSGQSSSYSQHGSGSGHSSG-YGQHGSRSGQSSRGERHGSSSGSSSRYGQHGS 2164
            G       SG S  YS  G  SG  SG +   G  SG  S G   G SSG  S     G 
Sbjct: 82   G------GSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGG--GGSSGGGSGCFSSGG 133

Query: 2165 GSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSS-- 2222
            G     G G   SG G    +       G  SS G  G GSG  SS G   S  G+S   
Sbjct: 134  GGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGG 193

Query: 2223 --VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHG 2280
                G    GSG     SQ  + +         G +SG        G  +G S      G
Sbjct: 194  SGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSG--------GGGSGGSGCFSSGG 245

Query: 2281 SGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 2336
             G S     G  G GSG   S G    G G S        G G  SS G  GSG G
Sbjct: 246  GGGSSGCGGGSSGIGSGCIISGGGSVCGGGSS-------GGGGGGSSVGGSGSGKG 294



 Score =  103 bits (257), Expect = 2e-21
 Identities = 107/298 (35%), Positives = 116/298 (38%), Gaps = 28/298 (9%)

Query: 2002 GYGQHGSSSGHSSTHGQHGSASGQSSS-CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS 2060
            G G  GS  G     G  GS  G S S CG  G         G   SG     G G  G 
Sbjct: 23   GGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGG 82

Query: 2061 GSGQSPGH-GQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSS 2119
            GSG S  + G  GS    S  +   G GSG  SS G      G SSG G    SSG   S
Sbjct: 83   GSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGG------GGSSGGGSGCFSSGGGGS 136

Query: 2120 YSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGS 2179
                G GSG  S  G  G  SGQ+ + + +G  S   S  G  GSG   S G G  GS  
Sbjct: 137  ---SGGGSGCFSSGG--GGFSGQAVQCQSYGGVSSGGSSGG--GSGCFSSGGGG--GSVC 187

Query: 2180 GHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQ 2239
            G+S      G GS   S  G   S     +S  P  S  G SS  G    GSG S  +S 
Sbjct: 188  GYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGG----GSGGSGCFSS 243

Query: 2240 HGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSG 2297
             G G    C  G  G  SG        GS  G  SS G  G      SS G  GSG G
Sbjct: 244  GGGGGSSGCGGGSSGIGSG--CIISGGGSVCGGGSSGGGGG-----GSSVGGSGSGKG 294



 Score =  103 bits (256), Expect = 3e-21
 Identities = 105/324 (32%), Positives = 125/324 (38%), Gaps = 35/324 (10%)

Query: 2229 SGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSS 2288
            SG G     S  G G G F   G  G +SG    +   G  +G     G  G G      
Sbjct: 20   SGGGGGGGGSG-GGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGG--GGG 76

Query: 2289 YGQQGSGSGQSPS-RGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESS 2347
             G  G GSG S    G  GS  G S  +   G GSG  SS G   SG G         S 
Sbjct: 77   IGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGG---------SG 127

Query: 2348 SWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHG 2407
             + S G    G GSG  SS    G  SGQ+ + + +G  S   SS G  GSG   S    
Sbjct: 128  CFSSGGGGSSGGGSGCFSS--GGGGFSGQAVQCQSYGGVSSGGSSGG--GSGCFSS---- 179

Query: 2408 QHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRS 2467
              G G G     S G  G G G S      GSGSG+ SS+   ++        G   S  
Sbjct: 180  --GGGGGSVCGYSGGGSGCGGGSSG-----GSGSGYVSSQQVTQTSCAPQPSYGGGSSGG 232

Query: 2468 GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGR 2527
            G S G G   S  G  S+ G  G +SG  S C     S G S   G    G    S  G 
Sbjct: 233  GGSGGSGCFSSGGGGGSS-GCGGGSSGIGSGC---IISGGGSVCGGGSSGGGGGGSSVGG 288

Query: 2528 QGSGSGQSPGHGQRGSGSRQSPSY 2551
             GSG G    H  +    +Q+P++
Sbjct: 289  SGSGKGVPICHQTQ---QKQAPTW 309



 Score =  102 bits (255), Expect = 4e-21
 Identities = 112/311 (36%), Positives = 121/311 (38%), Gaps = 41/311 (13%)

Query: 235 KSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSL 294
           K+S G   G    G G G   G G     SG  S G     S G   S G  G GS    
Sbjct: 18  KTSGGGGGGGGSGGGGCGFFGGGG-----SGGGSSGSGCGYSGGGGYSGGGCGGGSSGGG 72

Query: 295 GHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESG 354
           G G  G     S   V++  G G  SS G  G  SS     G + SG G +SG G   SG
Sbjct: 73  GGGGIGGCGGGSGGSVKYSGGGG--SSGGGSGCFSSGGGGSGCFSSGGGGSSGGG---SG 127

Query: 355 SGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRG 414
              S G    G GSG  SS G  G  SGQA           Q  SYG   S      G G
Sbjct: 128 CFSSGGGGSSGGGSGCFSSGG--GGFSGQAV----------QCQSYGGVSSGGSSGGGSG 175

Query: 415 QHSSGSGQSPGHGQRGSGSG-QSPSSGQHGTGFGRS-----SSSGPYVSGSGYSSGFGHH 468
             SSG G     G  G GSG    SSG  G+G+  S     +S  P  S  G SSG G  
Sbjct: 176 CFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGS 235

Query: 469 ESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSL 528
             S   SSG      G G SSG G   S  G        GS  G  SS G  G       
Sbjct: 236 GGSGCFSSG------GGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGG------- 282

Query: 529 GHSRHGSGSGQ 539
           G S  GSGSG+
Sbjct: 283 GSSVGGSGSGK 293



 Score =  102 bits (255), Expect = 4e-21
 Identities = 114/324 (35%), Positives = 123/324 (37%), Gaps = 56/324 (17%)

Query: 592 GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQ 651
           G  SG G  G   G  S  G  GS  G S   G  G   G  SS G  G G       G 
Sbjct: 26  GGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGG------IGG 79

Query: 652 QGSGSGQSPS-RGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQS 710
            G GSG S    G  GS  G S  +   G GSG  SS G  G  SG  SG     G G S
Sbjct: 80  CGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGG--GGSSGGGSGCFSSGGGGSS 137

Query: 711 SGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGS 770
            G    GSG   S G    G  SGQ+ + + +G  S   SS G  GSG   S G G  GS
Sbjct: 138 GG----GSGCFSSGG----GGFSGQAVQCQSYGGVSSGGSSGG--GSGCFSSGGGG--GS 185

Query: 771 GSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQ 830
             G+S      G  S   S  G   S     +SC    S  G +SG G    GSG     
Sbjct: 186 VCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGG----GSG----- 236

Query: 831 HGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQS 890
               SG FSS G  GS+     SSG                       G G   SG G  
Sbjct: 237 ---GSGCFSSGGGGGSSGCGGGSSG----------------------IGSGCIISGGGSV 271

Query: 891 PGHGQRGSGSGQSPSYGRHGSGSG 914
            G G  G G G S S G  GSG G
Sbjct: 272 CGGGSSGGGGGGS-SVGGSGSGKG 294



 Score =  102 bits (254), Expect = 5e-21
 Identities = 102/292 (34%), Positives = 112/292 (38%), Gaps = 44/292 (15%)

Query: 550 SGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSG-LGHQESRSGQSSGYGQHGSSSGHSS 608
           SG      +G  G G G S S   Y  G G+S G  G   S  G   G G  G  SG S 
Sbjct: 29  SGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSV 88

Query: 609 THGQHGSTSGQSSSCGQHGA------TSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSR 662
            +   G +SG  S C   G       +SG   S G  GSG   S   G  G GSG   S 
Sbjct: 89  KYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSG-GGSGCFSSGGGGSSGGGSGCFSSG 147

Query: 663 GRHGS-------DFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQ 715
           G   S        +G  SS G  G GSG  SS G  GSV G S G     GSG   G   
Sbjct: 148 GGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGG-----GSGCGGG--- 199

Query: 716 HGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHS 775
                  SSG    GS SG  S  +   +S     SYG   SG   S G G   SG G  
Sbjct: 200 -------SSG----GSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGG-- 246

Query: 776 PSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQG 827
                 G SSG     G  G G+ C  S G    G G + G G   S  G G
Sbjct: 247 ------GGSSG--CGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSG 290



 Score =  102 bits (253), Expect = 7e-21
 Identities = 111/331 (33%), Positives = 122/331 (36%), Gaps = 43/331 (12%)

Query: 1559 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 1618
            C +     G     G  G G     G G   SGS    G G  G G       G  G G 
Sbjct: 16   CVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGS----GCGYSGGG-------GYSGGGC 64

Query: 1619 GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG-YGQHGSRSGQSSRGE 1677
            G  SS G  G G+G   G       SG S  YS  G  SG  SG +   G  SG  S G 
Sbjct: 65   GGGSSGGGGGGGIGGCGG------GSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSG- 117

Query: 1678 RHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLG-HSSSHGQHGSGSG 1736
              G SS         GSG   S G G  G GSG   S G   SG      S+G   SG  
Sbjct: 118  -GGGSSGG-------GSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGS 169

Query: 1737 RSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQE 1796
                 G + S  G  SV G    GSG     S  GSGSG+  SQ        Q+S   Q 
Sbjct: 170  SGGGSGCFSSGGGGGSVCGYSGGGSGCGGG-SSGGSGSGYVSSQ-----QVTQTSCAPQP 223

Query: 1797 GSSTGQSSSHGQHGSGS-SQSSSYGQQGSGSGQSP-SRGRHGSGSGHSSSYGQHGSGSGW 1854
                G S   G  GSG  S     G  G G G S    G   SG G     G  G G G 
Sbjct: 224  SYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGG 283

Query: 1855 SSSSGRHGSGSGQSSGFGHH----ESSSWQS 1881
            SS     GSGSG+     H     ++ +W S
Sbjct: 284  SSVG---GSGSGKGVPICHQTQQKQAPTWPS 311



 Score =  101 bits (252), Expect = 9e-21
 Identities = 108/306 (35%), Positives = 121/306 (39%), Gaps = 38/306 (12%)

Query: 1054 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSS 1113
            ++  G   G G  G   G     G  G +SG  S CG  G         G   SG     
Sbjct: 18   KTSGGGGGGGGSGGGGCGFFGGGGSGGGSSG--SGCGYSGGGGYSGGGCGGGSSGGGGGG 75

Query: 1114 GYGRQGSGSGQSPGH-GQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHES 1172
            G G  G GSG S  + G  GS    S  +   G GSG  SS G   SG     G G   S
Sbjct: 76   GIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSG----GGSGCFSS 131

Query: 1173 SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGH 1232
              G SS     G GSG  S  G  G  SGQ+ + + +G  S   S  G  GSG   S G 
Sbjct: 132  GGGGSS-----GGGSGCFSSGG--GGFSGQAVQCQSYGGVSSGGSSGG--GSGCFSSGGG 182

Query: 1233 GRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSR-------GPYESRSGHSSVFG 1285
            G  GS  G+S      GSG G  SS    GSGSG  SS+        P  S  G SS  G
Sbjct: 183  G--GSVCGYSGG----GSGCGGGSS---GGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGG 233

Query: 1286 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQ 1345
                GSG S  +S  G G    C  G  G  SG        GS  G  SS G  G  S  
Sbjct: 234  ----GSGGSGCFSSGGGGGSSGCGGGSSGIGSG--CIISGGGSVCGGGSSGGGGGGSSVG 287

Query: 1346 SSGYGR 1351
             SG G+
Sbjct: 288  GSGSGK 293



 Score =  101 bits (252), Expect = 9e-21
 Identities = 106/323 (32%), Positives = 126/323 (39%), Gaps = 39/323 (12%)

Query: 823  GSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGR 882
            G G G    G   G F   G  G +SG               S  G      +   G G 
Sbjct: 22   GGGGGGGSGGGGCGFFGGGGSGGGSSG---------------SGCGYSGGGGYSGGGCGG 66

Query: 883  HGSGSGQSPGHGQRGSGSGQSPSY-GRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQS 941
              SG G   G G  G GSG S  Y G  GS  G S      G GSG  S  G  SS G S
Sbjct: 67   GSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGS 126

Query: 942  SGYTQHGSGS--GHSSSYEQHGSR-SGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQ 998
              ++  G GS  G S  +   G   SGQ+ + + +G  S   SS G  GSG   S G G 
Sbjct: 127  GCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGG--GSGCFSSGGGG- 183

Query: 999  HGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSG 1058
             GS  G S        GSG G  SS G   SGSG+ SS+   ++        G   S  G
Sbjct: 184  -GSVCGYSGG------GSGCGGGSSGG---SGSGYVSSQQVTQTSCAPQPSYGGGSSGGG 233

Query: 1059 QSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 1118
             S G G   S  G  S+ G  G +SG  S C     S G S   G    G    S  G  
Sbjct: 234  GSGGSGCFSSGGGGGSS-GCGGGSSGIGSGC---IISGGGSVCGGGSSGGGGGGSSVGGS 289

Query: 1119 GSGSGQSPGHGQRGSGSRQSPSY 1141
            GSG G    H  +    +Q+P++
Sbjct: 290  GSGKGVPICHQTQ---QKQAPTW 309



 Score =  101 bits (251), Expect = 1e-20
 Identities = 112/307 (36%), Positives = 121/307 (39%), Gaps = 35/307 (11%)

Query: 2124 GSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSP 2183
            G G G  SG G  G   G  S G   GS  G S      G G     G G   SG G   
Sbjct: 22   GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYS------GGGGYSGGGCGGGSSGGGGGG 75

Query: 2184 SRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSG 2243
              G  G GSG S  +   G  SG  S  G + S  G S  F    SG G SS     G G
Sbjct: 76   GIGGCGGGSGGSVKYSGGGGSSGGGS--GCFSSGGGGSGCFS---SGGGGSS-----GGG 125

Query: 2244 SGHFCSQGQHGSTSGQSSTFDQEGSS-TGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSR 2302
            SG F S G  GS+ G S  F   G   +GQ+     +G  SS  SS    G GSG   S 
Sbjct: 126  SGCF-SSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSS----GGGSGCFSSG 180

Query: 2303 GRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSG 2362
            G  GS  G+S   G  G G G S      GSGSG  S     ++S      Y    SG G
Sbjct: 181  GGGGSVCGYSG--GGSGCGGGSSG-----GSGSGYVSSQQVTQTSCAPQPSYGGGSSGGG 233

Query: 2363 HSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG 2422
             S       S  G  S G   G SSG  S     G GS    G G  G G G S   S G
Sbjct: 234  GSGGSGCFSSGGGGGSSG-CGGGSSGIGSGCIISGGGS--VCGGGSSGGGGGGS---SVG 287

Query: 2423 RHGSGSG 2429
              GSG G
Sbjct: 288  GSGSGKG 294



 Score =  100 bits (250), Expect = 2e-20
 Identities = 111/312 (35%), Positives = 122/312 (39%), Gaps = 43/312 (13%)

Query: 1524 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSS 1583
            ++  G   G G  G   G     G  G +SG  S CG  G         G   SG     
Sbjct: 18   KTSGGGGGGGGSGGGGCGFFGGGGSGGGSSG--SGCGYSGGGGYSGGGCGGGSSGGGGGG 75

Query: 1584 GYGRQGSGSGQSPGH-GQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHES 1642
            G G  G GSG S  + G  GS    S  +   G GSG  SS G   SG     G G   S
Sbjct: 76   GIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSG----GGSGCFSS 131

Query: 1643 SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGH 1702
              G SS     G GSG  S  G  G  SGQ+ + + +G  S   S  G  GSG   S G 
Sbjct: 132  GGGGSS-----GGGSGCFSSGG--GGFSGQAVQCQSYGGVSSGGSSGG--GSGCFSSGGG 182

Query: 1703 GRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSR-------GPYESRSGHSSVFG 1755
            G  GS  G S      GSG G  SS    GSGSG  SS+        P  S  G SS  G
Sbjct: 183  G--GSVCGYSGG----GSGCGGGSS---GGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGG 233

Query: 1756 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQ 1815
                GSG S  +S  G G    C  G  G  SG        GS  G  SS G  G     
Sbjct: 234  ----GSGGSGCFSSGGGGGSSGCGGGSSGIGSG--CIISGGGSVCGGGSSGGGGG----- 282

Query: 1816 SSSYGQQGSGSG 1827
             SS G  GSG G
Sbjct: 283  GSSVGGSGSGKG 294



 Score =  100 bits (250), Expect = 2e-20
 Identities = 102/291 (35%), Positives = 109/291 (37%), Gaps = 22/291 (7%)

Query: 1289 SGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSG 1348
            SG G     S  G G G F   G  G +SG    +   G  +G     G  G G     G
Sbjct: 20   SGGGGGGGGSG-GGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGG--GG 76

Query: 1349 YGRHGAGSGQSPS-RGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQ---SSGFGHH 1404
             G  G GSG S    G  GS  G S  +   G GSG  SS G   SG G    SSG G  
Sbjct: 77   IGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGG-- 134

Query: 1405 ESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSL 1464
              SS   SGC   G G G S    Q  S  G SS     G SSG  S     G G     
Sbjct: 135  -GSSGGGSGCFSSGGG-GFSGQAVQCQSYGGVSS-----GGSSGGGSGCFSSGGGGGSVC 187

Query: 1465 GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLG-HR 1523
            G+   GSG G   S      GSGSG  SS     +      S G   SG   S G G   
Sbjct: 188  GYSGGGSGCGGGSSG-----GSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFS 242

Query: 1524 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQ 1574
                G SSG G   S  G        GS  G  SS G  G SS   S  G+
Sbjct: 243  SGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGK 293



 Score =  100 bits (249), Expect = 2e-20
 Identities = 108/313 (34%), Positives = 124/313 (39%), Gaps = 35/313 (11%)

Query: 2464 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSS 2523
            ++  G   G G  G   G     G  G +SG  S CG  G         G   SG     
Sbjct: 18   KTSGGGGGGGGSGGGGCGFFGGGGSGGGSSG--SGCGYSGGGGYSGGGCGGGSSGGGGGG 75

Query: 2524 GYGRQGSGSGQSPGH-GQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHES 2582
            G G  G GSG S  + G  GS    S  +   G GSG  SS G   SG     G G   S
Sbjct: 76   GIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSG----GGSGCFSS 131

Query: 2583 SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGH 2642
              G SS     G GSG  S  G  G  SGQ+ + + +G  S   S  G  GSG   S G 
Sbjct: 132  GGGGSS-----GGGSGCFSSGG--GGFSGQAVQCQSYGGVSSGGSSGG--GSGCFSSGGG 182

Query: 2643 GRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHES--- 2699
            G  GS  G S      GSG G  SS    GSGSG  SS+   ++       +G   S   
Sbjct: 183  G--GSVCGYSGG----GSGCGGGSS---GGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGG 233

Query: 2700 GSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGY 2759
            GSG S  +S  G G    C  G  G  SG        GS  G  SS G  G GSS     
Sbjct: 234  GSGGSGCFSSGGGGGSSGCGGGSSGIGSG--CIISGGGSVCGGGSS-GGGGGGSS----V 286

Query: 2760 GRHGAGSGQSLSH 2772
            G  G+G G  + H
Sbjct: 287  GGSGSGKGVPICH 299



 Score = 98.6 bits (244), Expect = 8e-20
 Identities = 95/299 (31%), Positives = 101/299 (33%), Gaps = 31/299 (10%)

Query: 686 SSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSS 745
           +S G  G       G G   G G   G S  G G S   GY   G   G S      G  
Sbjct: 19  TSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGG----GGG 74

Query: 746 SGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCG 805
            G+    G  G     S G G  G GSG          SSG        G G+ C SS G
Sbjct: 75  GGIGGCGGGSGGSVKYSGGGGSSGGGSGCF--------SSG--------GGGSGCFSSGG 118

Query: 806 HYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSS 865
              SG G           SG G     S  G FS Q     + G  SS G     SG  S
Sbjct: 119 GGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFS 178

Query: 866 SYGQHESASHHASGRGRHGSGSGQSPGHGQRGS------GSGQSPSYGRHGSGSGRSSSS 919
           S G   S   ++ G    G GS    G G   S           PSYG   SG G S  S
Sbjct: 179 SGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGS 238

Query: 920 GRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSG 978
           G   SG G  S      SSG  SG    G GS         GS  G    S   GS SG
Sbjct: 239 GCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGG-----GSSGGGGGGSSVGGSGSG 292



 Score = 98.2 bits (243), Expect = 1e-19
 Identities = 101/283 (35%), Positives = 110/283 (38%), Gaps = 17/283 (6%)

Query: 443 GTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSS 502
           G G G   S G    G G+  G G    SS    GY    SG G  SG G  G  SG   
Sbjct: 21  GGGGGGGGSGG---GGCGFFGGGGSGGGSSGSGCGY----SGGGGYSGGGCGGGSSGGGG 73

Query: 503 RGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHG 562
            G   G   GS  S    G G     G     SG G S   S G   S    S  +   G
Sbjct: 74  GGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGG 133

Query: 563 YGSGRSSSRGPYESGSGHSSGLGHQ-ESRSGQSSGYGQHGSSSGHSSTHGQHGST---SG 618
            GS    S G + SG G  SG   Q +S  G SSG G  G  SG  S+ G  GS    SG
Sbjct: 134 GGSSGGGS-GCFSSGGGGFSGQAVQCQSYGGVSSG-GSSGGGSGCFSSGGGGGSVCGYSG 191

Query: 619 QSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSD-FGHSSSYGQ 677
             S CG  G +SG S S        +Q+S   Q   G G S   G  GS  F      G 
Sbjct: 192 GGSGCG--GGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGS 249

Query: 678 HGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGS 720
            G G G SS  G    +SG  S  G  S  G   G S  GSGS
Sbjct: 250 SGCGGG-SSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGS 291



 Score = 97.8 bits (242), Expect = 1e-19
 Identities = 107/300 (35%), Positives = 113/300 (37%), Gaps = 50/300 (16%)

Query: 1771 GSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSP 1830
            G G G     G  G   G  S     GS  G S   G  G G    SS G  G G G   
Sbjct: 22   GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGC- 80

Query: 1831 SRGRHGSGSGHSSSY----GQHGSGSGWSSS----SGRHGSGSGQSSGFGHHESSSWQSS 1882
                 G GSG S  Y    G  G GSG  SS    SG   SG G SSG G   S  + S 
Sbjct: 81   -----GGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGG---SGCFSSG 132

Query: 1883 GYTQHGSGSGHSSSYEQHGSRSGQSSR-----GEQHGSSSGSSSSYGQHGSGSRQSLGHG 1937
            G    G GSG  SS    G  SGQ+ +     G   G SSG  S     G G     G+ 
Sbjct: 133  GGGSSGGGSGCFSS--GGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYS 190

Query: 1938 QHGSGSGQSPSPSRGRHGSGSGQSS-------------SYGPYGSGSGWSSSRGPYES-G 1983
              GSG G   S      GSGSG  S             SYG   SG G S   G + S G
Sbjct: 191  GGGSGCGGGSSG-----GSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGG 245

Query: 1984 SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS-ASGQSSSCGQHGASSGQSSSH 2042
             G SSG G      G SSG G     SG  S  G   S   G  SS G  G+  G    H
Sbjct: 246  GGGSSGCG------GGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKGVPICH 299



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 103/315 (32%), Positives = 112/315 (35%), Gaps = 36/315 (11%)

Query: 276 SSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSR 335
           +SG     G  G G     G G  G GS         GSG G+S   G  G G       
Sbjct: 19  TSGGGGGGGGSGGGGCGFFGGGGSGGGSS--------GSGCGYSGGGGYSGGGC------ 64

Query: 336 GHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSR 395
           G   SG G   G G    GSG S  YS  G  SG  S     G       SSG  GSS  
Sbjct: 65  GGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSG- 123

Query: 396 QSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQ--HGTGFGRSSSSG 453
                           G G  SSG G S G G     SG    SGQ      +G  SS G
Sbjct: 124 ---------------GGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGG 168

Query: 454 PYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRS-GQSSRGERQGSSAG 512
               GSG  S  G   S   +S G +  G GS   SG G   S+   Q+S   +     G
Sbjct: 169 SSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGG 228

Query: 513 SSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRG 572
           SS   G  GSG   S G        G S     G   SG       G  G G G SS  G
Sbjct: 229 SSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGG 288

Query: 573 PYESGSGHSSGLGHQ 587
              SGSG    + HQ
Sbjct: 289 ---SGSGKGVPICHQ 300



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 106/302 (35%), Positives = 114/302 (37%), Gaps = 31/302 (10%)

Query: 1446 SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSS 1505
            +SG     G  G G     G G  GSG G S        GSG G S      G G G  S
Sbjct: 19   TSGGGGGGGGSGGGGCGFFGGG--GSGGGSS--------GSGCGYSGGGGYSGGGCGGGS 68

Query: 1506 SRGPYESGSSHSSGLGHRESRSGQSSGY-GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGA 1564
                  SG     G+G     SG S  Y G  GSS G S      G  SG  SS G  G 
Sbjct: 69   ------SGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGG--GG 120

Query: 1565 SSGQSSSHGQHGSGSSQSSGYGRQGSGSG-QSPGHGQRGSGSRQSPSYGRHGSGSGRSSS 1623
            SSG        GSG   S G G  G GSG  S G G     + Q  SYG   SG      
Sbjct: 121  SSG-------GGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGG 173

Query: 1624 SGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH-SSGYGQHGSRSGQSS--RGERHG 1680
            SG   SG G  S  G+    SG     S  GSGSG+ SS      S + Q S   G   G
Sbjct: 174  SGCFSSGGGGGSVCGYSGGGSGCGGG-SSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGG 232

Query: 1681 SSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSS 1740
              S  S  +   G G     G G  G GSG   S G    G G S   G   S  G  S 
Sbjct: 233  GGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSG 292

Query: 1741 RG 1742
            +G
Sbjct: 293  KG 294



 Score = 96.7 bits (239), Expect = 3e-19
 Identities = 104/305 (34%), Positives = 116/305 (38%), Gaps = 44/305 (14%)

Query: 1597 GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG 1656
            G G  GSG      +G  GSG G S      GSG G S G G+     G          G
Sbjct: 23   GGGGGGSGGGGCGFFGGGGSGGGSS------GSGCGYSGGGGYSGGGCG---------GG 67

Query: 1657 SGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSR-QSSGHGRQGSGSGQSPSR 1715
            S    G G  G   G S      G S + S   G  G GS   SSG G  GSG   S   
Sbjct: 68   SSGGGGGGGIGGCGGGS------GGSVKYSGGGGSSGGGSGCFSSGGG--GSGCFSSGGG 119

Query: 1716 GRHGSGLGHSSSHGQHGSGSGR---SSSRGPYESRSGHSSVFGQHESG--SGHSSAYSQH 1770
            G  G G G  SS G   SG G    SS  G +  ++     +G   SG  SG  S     
Sbjct: 120  GSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSS 179

Query: 1771 GSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSP 1830
            G G G  C     GS  G  S+    GS +G  SS     +  +   SYG   SG G S 
Sbjct: 180  GGGGGSVCGYSGGGSGCGGGSS---GGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSG 236

Query: 1831 SRGRHGSGSGHSSS---YGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQH 1887
              G   SG G  SS    G  G GSG   S G    G G S G G          G +  
Sbjct: 237  GSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGG---------GGSSVG 287

Query: 1888 GSGSG 1892
            GSGSG
Sbjct: 288  GSGSG 292



 Score = 96.3 bits (238), Expect = 4e-19
 Identities = 104/318 (32%), Positives = 117/318 (36%), Gaps = 41/318 (12%)

Query: 1028 RSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSS 1087
            ++  G     G    G G   G G     SG   GY   G  SG     G  G +SG   
Sbjct: 18   KTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSG----GGCGGGSSGGGG 73

Query: 1088 SCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSG 1147
              G  G   G   S    G G S   G G   SG G        GSG   S   G  G G
Sbjct: 74   GGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGG--------GSGCFSSGGGGSSGGG 125

Query: 1148 SGRSSSSGQHGSGLGE---SSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 1204
            SG  SS G   SG G    SSG G     + Q  SY   G  SG SSG G     SG  S
Sbjct: 126  SGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYG--GVSSGGSSGGG-----SGCFS 178

Query: 1205 RGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSG 1264
             G   GS  G    Y   GSG     G    GSGSG+  S+    +      S+G   SG
Sbjct: 179  SGGGGGSVCG----YSGGGSG---CGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSG 231

Query: 1265 SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHG---SGSGHFCSQGQHGSTSGQSS 1321
             G S   G + S  G  S      SG G  S+    G   SG G  C  G  G   G SS
Sbjct: 232  GGGSGGSGCFSSGGGGGS------SGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSS 285

Query: 1322 TFDQEGSSTGQSSSYGHR 1339
                 GS +G+     H+
Sbjct: 286  V---GGSGSGKGVPICHQ 300



 Score = 95.5 bits (236), Expect = 7e-19
 Identities = 99/285 (34%), Positives = 106/285 (37%), Gaps = 20/285 (7%)

Query: 743  GSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSS 802
            G   G  S  G  G      SG G  GSG G+S      G   G  SS G  G G     
Sbjct: 22   GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIG--- 78

Query: 803  SCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQG--RHGSTSGQSSSSGQHDSS 860
             CG    GS + SG G    G    +S  G  SG FSS G    G  SG  SS G   S 
Sbjct: 79   GCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSG 138

Query: 861  SGQ---SSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGR-S 916
             G    SS  G     +      G   SG     G G   SG G     G  G GSG   
Sbjct: 139  GGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGG 198

Query: 917  SSSGRHGSGSGQSSGFGHKSSSGQSS--GYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHG 974
             SSG  GSG   S      S + Q S  G +  G GSG S  +    S  G    S   G
Sbjct: 199  GSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCF----SSGGGGGSSGCGG 254

Query: 975  SSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSG 1019
             SSG  S     G GS    G G  G G G S   S G  GSG G
Sbjct: 255  GSSGIGSGCIISGGGS--VCGGGSSGGGGGGS---SVGGSGSGKG 294



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 99/298 (33%), Positives = 113/298 (37%), Gaps = 29/298 (9%)

Query: 562 GYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSS 621
           G G G  S  G      G  SG G   S  G S G G  G   G  S+ G  G   G   
Sbjct: 22  GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIG--- 78

Query: 622 SCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSG 681
            CG  G + G     G  GS    S  +   G GSG   S G  GS  G S  +   G G
Sbjct: 79  GCG--GGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGG-GSSGGGSGCFSSGGGG 135

Query: 682 SGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQ 741
               SS G  G  S    GF     SGQ+     +G  SS        G  SG  S    
Sbjct: 136 ----SSGGGSGCFSSGGGGF-----SGQAVQCQSYGGVSS--------GGSSGGGSGCFS 178

Query: 742 HGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCS 801
            G   G    Y   GSG     G    GSGSG+  S+    +S     S+G   SG   S
Sbjct: 179 SGGGGGSVCGYSGGGSG---CGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGS 235

Query: 802 SSCGHYES-GSGQASGFGQHESGSGQG--YSQHGSASGHFSSQGRHGSTSGQSSSSGQ 856
              G + S G G +SG G   SG G G   S  GS  G  SS G  G +S   S SG+
Sbjct: 236 GGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGK 293



 Score = 93.6 bits (231), Expect = 3e-18
 Identities = 97/304 (31%), Positives = 105/304 (34%), Gaps = 14/304 (4%)

Query: 479 TQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSG 538
           T  G G G  SG G  G   G  S G   GS  G S   G  G G          G G G
Sbjct: 19  TSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIG 78

Query: 539 QSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYG 598
                S G  +      SS G  G  S      G + SG G SSG G   S    S G G
Sbjct: 79  GCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGG---SGCFSSGGGG 135

Query: 599 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHG---SGSSQSSRYGQQGSG 655
             G  SG  S+ G  G  SGQ+  C  +G  S   SS G  G   SG    S  G  G G
Sbjct: 136 SSGGGSGCFSSGG--GGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGG 193

Query: 656 SG-QSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYS 714
           SG    S G  GS +  S    Q       S   G  G      SG     G G SSG  
Sbjct: 194 SGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCG 253

Query: 715 QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGH 774
              SG          GS  G  S         G  SS G  GSG      H  Q   +  
Sbjct: 254 GGSSGIGSGCIISGGGSVCGGGS-----SGGGGGGSSVGGSGSGKGVPICHQTQQKQAPT 308

Query: 775 SPSR 778
            PS+
Sbjct: 309 WPSK 312



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 100/295 (33%), Positives = 106/295 (35%), Gaps = 37/295 (12%)

Query: 313 GSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSS 372
           GSG G     G  GSG   S S   Y  G G         SG G   G S  G G G   
Sbjct: 28  GSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGY--------SGGGCGGGSSGGGGGGGIGG 79

Query: 373 SQGQHGS----TSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQ--HSSGSGQSPGH 426
             G  G     + G  SS G  G  S      G   S    SSG G    SSG G S G 
Sbjct: 80  CGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGG 139

Query: 427 GQRGSGSGQSPSSGQ--HGTGFGRSSSSGPYVSGSG-YSSGFGHHESSSEHSSGYTQHGS 483
           G     SG    SGQ      +G  SS G    GSG +SSG G          GY+  GS
Sbjct: 140 GSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGG-----GGSVCGYSGGGS 194

Query: 484 GSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSP 543
           G G   G    GS SG  S  +   +S     SYG   SG   S G     SG G   S 
Sbjct: 195 GCG---GGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSG 251

Query: 544 SRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYG 598
             G            G  G GSG   S G    G G S G G   S  G  SG G
Sbjct: 252 CGG------------GSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKG 294



 Score = 90.1 bits (222), Expect = 3e-17
 Identities = 102/295 (34%), Positives = 112/295 (37%), Gaps = 28/295 (9%)

Query: 357 QSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQH 416
           ++SG    G GSG     G  G   G  S  G  GS    S   G          G G  
Sbjct: 18  KTSGGGGGGGGSG----GGGCGFFGGGGSGGGSSGSGCGYSGGGGY------SGGGCGGG 67

Query: 417 SSGSGQSPGHGQRGSGSG----QSPSSGQHGTGFGRSSS----SGPYVSGSGYSSGFGHH 468
           SSG G   G G  G GSG     S   G  G G G  SS    SG + SG G SSG G  
Sbjct: 68  SSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGG-- 125

Query: 469 ESSSEHSSGYTQHGSGSG-HSSGHGQHGSRS--GQSSRGERQGSSAGSSSSYGQHGSGSR 525
            S    S G    G GSG  SSG G    ++   QS  G   G S+G  S     G G  
Sbjct: 126 -SGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGG 184

Query: 526 QSLGHSRHGSGSGQSPSPSRGRHESGSRQ--SSSYGPH-GYGSGRSSSRGPYESGSGHSS 582
              G+S  GSG G   S   G     S+Q   +S  P   YG G S   G   SG   S 
Sbjct: 185 SVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSG 244

Query: 583 GLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGS-TSGQSSSCGQHGATSGQSSSH 636
           G G      G SSG G     SG  S  G   S   G  SS G  G+  G    H
Sbjct: 245 GGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKGVPICH 299



 Score = 89.7 bits (221), Expect = 4e-17
 Identities = 99/289 (34%), Positives = 108/289 (37%), Gaps = 32/289 (11%)

Query: 365 GSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSP 424
           G G G  S  G  G   G  S  G  GS    S   G          G G  SSG G   
Sbjct: 22  GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYS------GGGCGGGSSGGGGGG 75

Query: 425 GHGQRGSGSG----QSPSSGQHGTGFGRSSS----SGPYVSGSGYSSGFGHHESSSEHSS 476
           G G  G GSG     S   G  G G G  SS    SG + SG G SSG G   S    S 
Sbjct: 76  GIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGG---SGCFSSG 132

Query: 477 GYTQHGSGSG-HSSGHGQHGSRSGQ--SSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRH 533
           G    G GSG  SSG G    ++ Q  S  G   G S+G  S     G G     G+S  
Sbjct: 133 GGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGG 192

Query: 534 GSGSGQSPSPSRGRHESGSRQ--SSSYGPH-GYGSGRSSSRGPYESGSGHSSGLG-HQES 589
           GSG G   S   G     S+Q   +S  P   YG G         SG G S G G     
Sbjct: 193 GSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGG--------SSGGGGSGGSGCFSSG 244

Query: 590 RSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQ 638
             G SSG G   S  G        GS  G  SS G  G +S   S  G+
Sbjct: 245 GGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGK 293



 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 83/237 (35%), Positives = 92/237 (38%), Gaps = 35/237 (14%)

Query: 2600 SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHG 2659
            +SG G  G  SG    G   G  SG     G  GSG   S G G  G G G   S G  G
Sbjct: 19   TSGGGGGGGGSGGGGCGFFGGGGSGG----GSSGSGCGYSGGGGYSGGGCGGGSSGGGGG 74

Query: 2660 SGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCS 2719
             G+G        G GSG            G     G   S  G S  +S  G GSG F S
Sbjct: 75   GGIGGC------GGGSG------------GSVKYSGGGGSSGGGSGCFSSGGGGSGCF-S 115

Query: 2720 QGQHGSTSGQSSTFDQ--EGSSTGQSSSYGHRGSGSS----QSSGYGRHGAGSGQSLSHG 2773
             G  GS+ G S  F     GSS G S  +   G G S    Q   YG   +G       G
Sbjct: 116  SGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSG 175

Query: 2774 RHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSG-----QDGYSYCKGGSNHDGGSSG 2825
               SG G  S  G  G GSG   G S  GSGSG     Q   + C    ++ GGSSG
Sbjct: 176  CFSSGGGGGSVCGYSGGGSGCGGG-SSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSG 231



 Score = 84.3 bits (207), Expect = 2e-15
 Identities = 80/206 (38%), Positives = 83/206 (40%), Gaps = 20/206 (9%)

Query: 2633 GSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSS 2692
            G G    SG G  G   G     G  GSG G+S   G  G G G  SS G      G   
Sbjct: 22   GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGG------GGGG 75

Query: 2693 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSG 2752
              G    GSG S  YS  G  SG     G   S  G S  F    SS G  SS G  GSG
Sbjct: 76   GIGGCGGGSGGSVKYSGGGGSSGG--GSGCFSSGGGGSGCF----SSGGGGSSGG--GSG 127

Query: 2753 SSQSSGYGRHGAGSGQSLSHGRHGSGSG-QSSSYG---QHGSGSGQSSGYSQHGSGSGQD 2808
               S G G  G GSG   S G   SG   Q  SYG     GS  G S  +S  G G    
Sbjct: 128  CFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVC 187

Query: 2809 GYSYCKGGSNHDGGSSGSYFLSFPSS 2834
            GYS   GGS   GGSSG     + SS
Sbjct: 188  GYS--GGGSGCGGGSSGGSGSGYVSS 211



 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 93/272 (34%), Positives = 99/272 (36%), Gaps = 51/272 (18%)

Query: 2568 GSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSS 2627
            G G G  SG G      G  S     GSG G+S G G  G   G  S G   G   G   
Sbjct: 22   GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCG 81

Query: 2628 HYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESR 2687
              G  G   + S G G  G GSG                S G  GSG   S   G   S 
Sbjct: 82   --GGSGGSVKYSGGGGSSGGGSG--------------CFSSGGGGSGCFSSGGGG---SS 122

Query: 2688 LGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD-----QEGSSTGQ 2742
             G S  F    SG G SS     G GSG F S G  G  SGQ+           G S+G 
Sbjct: 123  GGGSGCF---SSGGGGSS-----GGGSGCFSSGG--GGFSGQAVQCQSYGGVSSGGSSGG 172

Query: 2743 SSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSS-------------SYGQHG 2789
             S     G G     GY   G+G G   S    GSGSG  S             SYG   
Sbjct: 173  GSGCFSSGGGGGSVCGYSGGGSGCGGGSS---GGSGSGYVSSQQVTQTSCAPQPSYGGGS 229

Query: 2790 SGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDG 2821
            SG G S G     SG G  G S C GGS+  G
Sbjct: 230  SGGGGSGGSGCFSSGGG-GGSSGCGGGSSGIG 260



 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 91/271 (33%), Positives = 104/271 (38%), Gaps = 44/271 (16%)

Query: 166 SGQHNSYSG----QSSSYGEQNSDSHQSSGRGQCGSGSGQSPNY----GQHGSGSGQSSS 217
           SG    YSG         G  +S      G G CG GSG S  Y    G  G GSG  SS
Sbjct: 47  SGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSS 106

Query: 218 ----NDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSR-SGQSSRGER 272
               +    SG G SSG      SSG   G S  GSG   S G G  G     QS  G  
Sbjct: 107 GGGGSGCFSSGGGGSSGGGSGCFSSG-GGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVS 165

Query: 273 HRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSH---------- 322
              SSG  S     G G     G+   GSG     S    GSGSG+ SS           
Sbjct: 166 SGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSG---GSGSGYVSSQQVTQTSCAPQ 222

Query: 323 --------GQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQ 374
                   G  GSG S  +S G    G G +SG G   SG G     S  GS  G  SS 
Sbjct: 223 PSYGGGSSGGGGSGGSGCFSSG----GGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSG 278

Query: 375 GQHGSTSGQASSSGQ-----HGSSSRQSSSY 400
           G  G +S   S SG+     H +  +Q+ ++
Sbjct: 279 GGGGGSSVGGSGSGKGVPICHQTQQKQAPTW 309



 Score = 59.3 bits (142), Expect = 5e-08
 Identities = 45/132 (34%), Positives = 53/132 (40%), Gaps = 10/132 (7%)

Query: 2699 SGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSG 2758
            SG G     S  G G G F   G  G +SG    +   G  +G     G  G G     G
Sbjct: 20   SGGGGGGGGSG-GGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGG--GGG 76

Query: 2759 YGRHGAGSGQSLSH-GRHGSGSGQSSSYGQHGSGSG--QSSGYSQHGSGSGQDGYSYCKG 2815
             G  G GSG S+ + G  GS  G S  +   G GSG   S G    G GSG     +  G
Sbjct: 77   IGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSG----CFSSG 132

Query: 2816 GSNHDGGSSGSY 2827
            G    GG SG +
Sbjct: 133  GGGSSGGGSGCF 144



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 72/224 (32%), Positives = 75/224 (33%), Gaps = 49/224 (21%)

Query: 165 FSGQHNSYSGQSSSY--GEQNSDSHQSSGRGQCGSGSG--QSPNYGQHGSGSGQSSSNDT 220
           +SG   S  G S  +  G   S    S G G  G GSG   S   G  G GSG  SS   
Sbjct: 90  YSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGG 149

Query: 221 HGSGSG---QSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRS-- 275
             SG     QS G      SSG  SG    G G G   GY   GS  G  S G       
Sbjct: 150 GFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYV 209

Query: 276 -------------------SSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGS 316
                              SSG     G  GSG   S G    G GS          SG 
Sbjct: 210 SSQQVTQTSCAPQPSYGGGSSGGG---GSGGSGCFSSGG----GGGS----------SGC 252

Query: 317 GHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSG 360
           G  SS    G GS    S G    G G + G G   S  G  SG
Sbjct: 253 GGGSS----GIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSG 292



 Score = 41.6 bits (96), Expect = 0.011
 Identities = 32/95 (33%), Positives = 36/95 (37%), Gaps = 17/95 (17%)

Query: 2742 QSSSYGHRGSGS---------SQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGS 2792
            ++S  G  G GS            SG G  G+G G S   G  G G G  SS G  G G 
Sbjct: 18   KTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGI 77

Query: 2793 GQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGSY 2827
            G        G G G  G     GG    GG SG +
Sbjct: 78   G--------GCGGGSGGSVKYSGGGGSSGGGSGCF 104


>gi|89276766 trophinin isoform 5 [Homo sapiens]
          Length = 1431

 Score =  112 bits (279), Expect = 7e-24
 Identities = 204/769 (26%), Positives = 290/769 (37%), Gaps = 90/769 (11%)

Query: 2071 RGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 2130
            RG+ +R   S G   S +G  SSSG    G G + G     S+S  +++    G     S
Sbjct: 725  RGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTS 784

Query: 2131 SGYGQHGSRS-GQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHG 2189
            S +    S S G +       SS  S S  G   + +  S G     SG   + +    G
Sbjct: 785  SSFSSAASISFGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGG 844

Query: 2190 SGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGS-GHSSAYSQHGSGSGHFC 2248
            + SG   +       SG  S+   + S    S+VF    S S G     S      G   
Sbjct: 845  ASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFSSALSTSTGFGGILSTSVCFGGSPS 904

Query: 2249 SQGQHGSTSGQSSTFDQEGSST----GQSSSHGQHGSGSSQSSSYGQQGSGS---GQSPS 2301
            S G  G T   S  F     ++    G  S+    G  SS S+++G   S S     SPS
Sbjct: 905  SSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPS 964

Query: 2302 RGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGS 2361
             G    G+ ++S+      GS  ++S+G  G     S+ FG   S+S    G    G+  
Sbjct: 965  TGAGFGGALNTSA----SFGSVLNTSTG-FGGAMSTSADFGGTLSTSVCFGG--SPGTSV 1017

Query: 2362 GHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR 2421
               S+   +    G  S     G +  +S  +G   S S    G     +  G + S S 
Sbjct: 1018 SFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVSTSA 1077

Query: 2422 GRHGSGSGQSS-SYSPY---GSGSGWSSSRG-------PYESGSGHSSGLGHRESRSGQS 2470
               G+ S  +  S +P    G G  +S+S G         + G   S+ +G   + S   
Sbjct: 1078 SFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSV 1137

Query: 2471 SGYGQHGSS---SGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGR 2527
            S  G HG+S    G  ST    GS S  +   G   ++S   S       G++  S    
Sbjct: 1138 SFGGAHGTSLCFGGAPSTSLCFGSASNTNLCFGGPPSTSACFS-------GATSPSFCDG 1190

Query: 2528 QGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS 2587
              + +G S G+G   +           G G G ++S+G  G GLG S+GF      SG  
Sbjct: 1191 PSTSTGFSFGNGLSTNA----------GFGGGLNTSAG-FGGGLGTSAGF------SGGL 1233

Query: 2588 SSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGS 2647
            S+ S    G G S+G+G  G     +  G   G+S+G S   G               G 
Sbjct: 1234 STSSGFDGGLGTSAGFG--GGPGTSTGFGGGLGTSAGFSGGLGTSA------------GF 1279

Query: 2648 GSGQSPSRGRHGSGLGHSSSHGQH-GSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSA 2706
            G G   S G  G GLG ++S G   G+ +G S         L  S  FG   + S     
Sbjct: 1280 GGGLVTSDG-FGGGLGTNASFGSTLGTSAGFSGG-------LSTSDGFGSRPNASFDRGL 1331

Query: 2707 YSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRG---SGSSQSSGYGRHG 2763
             +  G GSG   S G  G  S  +      G S+G SS  G  G   +G    SG    G
Sbjct: 1332 STIIGFGSGSNTSTGFTGEPSTST------GFSSGPSSIVGFSGGPSTGVGFCSGPSTSG 1385

Query: 2764 AGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSY 2812
               G S   G    G G ++  G  G G   S+G+    +  G  G+SY
Sbjct: 1386 FSGGPSTGAG---FGGGPNTGAG-FGGGPSTSAGFGSGAASLGACGFSY 1430



 Score =  110 bits (276), Expect = 2e-23
 Identities = 196/737 (26%), Positives = 273/737 (37%), Gaps = 77/737 (10%)

Query: 1366 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSS 1425
            G+ +    S G   S +G  SSSG    G G + G     S+S+ ++     G     SS
Sbjct: 726  GASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSS 785

Query: 1426 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1485
            S+    S S   +       SS +S S+G     S  S   G   S SG   + +    G
Sbjct: 786  SFSSAASISFGCAHSTSTSFSSEASISFGGMPCTS-ASFSGGVSSSFSGPLSTSATFSGG 844

Query: 1486 SGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSS----G 1541
            + SG   + S     SG  S+   + S  + S+      S    S+G+G   S+S    G
Sbjct: 845  ASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVF---SSALSTSTGFGGILSTSVCFGG 901

Query: 1542 HSSTHGQHGSTSGQSSSCGQHGASS----GQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG 1597
              S+ G  G T   S   G    +S    G  S+    G  SS S+ +G   S S    G
Sbjct: 902  SPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDG 961

Query: 1598 HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS 1657
                G+G              G  ++S   GS L  S+GFG      G  S+ +  G   
Sbjct: 962  SPSTGAGF------------GGALNTSASFGSVLNTSTGFG------GAMSTSADFGGTL 1003

Query: 1658 GHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGR 1717
              S  +G      G        GS+  +++ YG   S +    G        G SPS   
Sbjct: 1004 STSVCFG------GSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSA 1057

Query: 1718 -HGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGH 1776
              G  L  ++S G   S S   S      + S  +   G   +  G   A+S      G 
Sbjct: 1058 GFGGALNTNASFGCAVSTSASFSG-----AVSTSACFSGAPITNPGFGGAFSTSAGFGGA 1112

Query: 1777 FCSQGQHGSTSGQSSTFDQEGS-STGQSSSHGQ---HGSGSSQSSSYGQQGSGS---GQS 1829
              +    G T   S  F    S S     +HG     G   S S  +G   + +   G  
Sbjct: 1113 LSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLCFGGAPSTSLCFGSASNTNLCFGGP 1172

Query: 1830 PSRGRHGSGS-------GHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 1882
            PS     SG+       G S+S G    G+G S+++G  G G   S+GFG    +S   S
Sbjct: 1173 PSTSACFSGATSPSFCDGPSTSTG-FSFGNGLSTNAG-FGGGLNTSAGFGGGLGTSAGFS 1230

Query: 1883 G--YTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQ---HGSGSRQSLGHG 1937
            G   T  G   G  +S    G     +  G   G+S+G S   G     G G   S G G
Sbjct: 1231 GGLSTSSGFDGGLGTSAGFGGGPGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTSDGFG 1290

Query: 1938 QHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRG-----PYESGSGHSSGL-G 1991
              G G+  S   + G     SG  S+   +GS    S  RG      + SGS  S+G  G
Sbjct: 1291 -GGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDRGLSTIIGFGSGSNTSTGFTG 1349

Query: 1992 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQH-----G 2046
               + +G SSG       SG  ST    G  SG S+S    G S+G     G +     G
Sbjct: 1350 EPSTSTGFSSGPSSIVGFSGGPST--GVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFG 1407

Query: 2047 SGSSQSSGYGRQGSGSG 2063
             G S S+G+G   +  G
Sbjct: 1408 GGPSTSAGFGSGAASLG 1424



 Score =  108 bits (269), Expect = 1e-22
 Identities = 199/755 (26%), Positives = 283/755 (37%), Gaps = 78/755 (10%)

Query: 1601 RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 1660
            RG+ +R   S G   S +G  SSSG    G G + G     S+S  +++    G     S
Sbjct: 725  RGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTS 784

Query: 1661 SGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSG--QSPSRGRH 1718
            S +    S S   +       SS +S  +G     S   SG G   S SG   + +    
Sbjct: 785  SSFSSAASISFGCAHSTSTSFSSEASISFGGMPCTSASFSG-GVSSSFSGPLSTSATFSG 843

Query: 1719 GSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGS-GHSSAYSQHGSGSGHF 1777
            G+  G   +       SG  S+   + S    S+VF    S S G     S      G  
Sbjct: 844  GASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFSSALSTSTGFGGILSTSVCFGGSP 903

Query: 1778 CSQGQHGSTSGQSSTFDQEGSST----GQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRG 1833
             S G  G T   S  F     ++    G  S+    G  SS S+++G  G+ S      G
Sbjct: 904  SSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFG--GTLSTSICFDG 961

Query: 1834 RHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGH 1893
               +G+G   +     S     ++S   G     S+ FG   S+S    G    G+    
Sbjct: 962  SPSTGAGFGGALNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGG--SPGTSVSF 1019

Query: 1894 SSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGR 1953
             S+   +    G  S     G +  +S  +G   S S    G     +  G + S S   
Sbjct: 1020 GSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVSTSASF 1079

Query: 1954 HGSGSGQSSSYGP----YGSGSGWSSSRG-------PYESGSGHSSGLGHRESRSGQSSG 2002
             G+ S  +   G      G G  +S+S G         + G   S+ +G   + S   S 
Sbjct: 1080 SGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSF 1139

Query: 2003 YGQHGSS---SGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 2059
             G HG+S    G  ST    GSAS  +   G   ++S          SG++  S      
Sbjct: 1140 GGAHGTSLCFGGAPSTSLCFGSASNTNLCFGGPPSTSACF-------SGATSPSFCDGPS 1192

Query: 2060 SGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSS 2119
            + +G S G+G   +           G G G ++S+G  G GLG S+GF      SG  S+
Sbjct: 1193 TSTGFSFGNGLSTNA----------GFGGGLNTSAG-FGGGLGTSAGF------SGGLST 1235

Query: 2120 YSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQ---HGSGSRQSSGH-GRQ 2175
             S    G G S+G+G  G     +  G   G+S+G S   G     G G   S G  G  
Sbjct: 1236 SSGFDGGLGTSAGFG--GGPGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGL 1293

Query: 2176 GSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 2235
            G+ +    + G     SG  S+    GS    S  R       G S++ G   SGS  S+
Sbjct: 1294 GTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDR-------GLSTIIG-FGSGSNTST 1345

Query: 2236 AYSQHGSGSGHFCSQGQHGSTSGQSSTFD-QEGSSTGQSSSHGQHGSGSSQSSSYGQQGS 2294
             ++   S S         G +SG SS      G STG     G   SG S   S    G+
Sbjct: 1346 GFTGEPSTS--------TGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPS---TGA 1394

Query: 2295 GSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSG 2329
            G G  P+ G  G G G S+S G  GSG+    + G
Sbjct: 1395 GFGGGPNTGA-GFGGGPSTSAG-FGSGAASLGACG 1427



 Score =  106 bits (265), Expect = 3e-22
 Identities = 209/764 (27%), Positives = 280/764 (36%), Gaps = 96/764 (12%)

Query: 1131 RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 1190
            RG+ +R   S G   S +G  SSSG    G G + G     S+S  +++    G     S
Sbjct: 725  RGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTS 784

Query: 1191 SGYGQHGSRS-GQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHG 1249
            S +    S S G +       SS  S S  G   + +  S G     SG   + +    G
Sbjct: 785  SSFSSAASISFGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGG 844

Query: 1250 SGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGS-GHSSAYSQHGSGSGHFC 1308
            +  G   +       SG  S+   + S    S+VF    S S G     S      G   
Sbjct: 845  ASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFSSALSTSTGFGGILSTSVCFGGSPS 904

Query: 1309 SQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSG 1368
            S G  G T   S  F   G S   S+ +G   S S    G     A  G + S      G
Sbjct: 905  SSGSFGGTLSTSICF---GGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDG 961

Query: 1369 SGHSSSYGQHGSGSGWS-SSSGRHGSGSGQSSGFGHHESSSWQSSGCTQ----HGSGSGH 1423
            S  +      G+G G + ++S   GS    S+GFG   S+S    G        G   G 
Sbjct: 962  SPST------GAGFGGALNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGT 1015

Query: 1424 SSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGR 1483
            S S+                GS+  +++ YG   S +    G        G SPS S G 
Sbjct: 1016 SVSF----------------GSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGF 1059

Query: 1484 HGSGSGQSS---SYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRS----GQSSGYGQH 1536
             G+ +  +S   + S   S SG  S+   +      + G G   S S    G  S     
Sbjct: 1060 GGALNTNASFGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADF 1119

Query: 1537 GSSSGHSSTHGQHGSTSGQSSSCGQHGAS---SGQSSSHGQHGSGSSQSSGYGRQGSGSG 1593
            G +  +S   G   STS   S  G HG S    G  S+    GS S+ +  +G   S S 
Sbjct: 1120 GGTPSNSIGFGAAPSTS--VSFGGAHGTSLCFGGAPSTSLCFGSASNTNLCFGGPPSTSA 1177

Query: 1594 QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS----GQSSS 1649
               G          S S G    G+G S+++G  G GL  S+GFG    +S    G  S+
Sbjct: 1178 CFSGATSPSFCDGPSTSTG-FSFGNGLSTNAG-FGGGLNTSAGFGGGLGTSAGFSGGLST 1235

Query: 1650 YSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQ-GSG 1708
             S    G G S+G+G               G    S+   G  G+ +  S G G   G G
Sbjct: 1236 SSGFDGGLGTSAGFG---------------GGPGTSTGFGGGLGTSAGFSGGLGTSAGFG 1280

Query: 1709 SGQSPSRGRHGSGLGHSSSHGQH-----GSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 1763
             G   S G  G GLG ++S G       G   G S+S G           FG   + S  
Sbjct: 1281 GGLVTSDG-FGGGLGTNASFGSTLGTSAGFSGGLSTSDG-----------FGSRPNASFD 1328

Query: 1764 SSAYSQHGSGSGHFCSQG-------QHGSTSGQSSTFD-QEGSSTGQSSSHGQHGSGSSQ 1815
                +  G GSG   S G         G +SG SS      G STG     G   SG S 
Sbjct: 1329 RGLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSG 1388

Query: 1816 SSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSG 1859
              S    G+G G  P+ G  G G G S+S G  GSG+    + G
Sbjct: 1389 GPS---TGAGFGGGPNTGA-GFGGGPSTSAG-FGSGAASLGACG 1427



 Score =  104 bits (259), Expect = 1e-21
 Identities = 204/760 (26%), Positives = 282/760 (37%), Gaps = 93/760 (12%)

Query: 1950 SRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGS-----GHSSGLGHRESRSGQSSGYG 2004
            S G   S +G  SS G +  G G +    P  S S       S G     S S  S+   
Sbjct: 734  SDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSSSFSSAASI 793

Query: 2005 QHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ 2064
              G +   S++     S S     C     S G SSS     S S+  SG    G G   
Sbjct: 794  SFGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTL 853

Query: 2065 SPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLG----ESSGFGHHESSSGQS--- 2117
            S   G  G  S  S S+G   + S   SS+     G G     S  FG   SSSG     
Sbjct: 854  STTAGFSGVLST-STSFGSAPTTSTVFSSALSTSTGFGGILSTSVCFGGSPSSSGSFGGT 912

Query: 2118 -SSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQG 2176
             S+    G     S+G+G      G  S     G SS +S+ +G  G+ S      G   
Sbjct: 913  LSTSICFGGSPCTSTGFG------GTLSTSVSFGGSSSTSANFG--GTLSTSICFDGSPS 964

Query: 2177 SGSGHSPSRGRHGS-GSGHSSSHGQHGSGS------GRSSSRGPYESRSGHSSVFGQH-E 2228
            +G+G   +     S GS  ++S G  G+ S      G  S+   +    G S  FG    
Sbjct: 965  TGAGFGGALNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALN 1024

Query: 2229 SGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSS 2288
            + +G+  A S +    G   +    G +   S+ F       G  +++   G   S S+S
Sbjct: 1025 TNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFG------GALNTNASFGCAVSTSAS 1078

Query: 2289 YGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSS 2348
            +   G+ S  +   G   +  G   ++       G  S++   G     S GFG   S+S
Sbjct: 1079 FS--GAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTS 1136

Query: 2349 WQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQ 2408
                     G   G S  +       G  S     GS+S ++  +G  G  S  +   G 
Sbjct: 1137 ------VSFGGAHGTSLCF------GGAPSTSLCFGSASNTNLCFG--GPPSTSACFSGA 1182

Query: 2409 HGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGL-GHRESRS 2467
                    PS S G    G+G S++    G G G ++S G +  G G S+G  G   + S
Sbjct: 1183 TSPSFCDGPSTSTG-FSFGNGLSTNA---GFGGGLNTSAG-FGGGLGTSAGFSGGLSTSS 1237

Query: 2468 GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGR 2527
            G   G G      G   T    G   G S+     G S G  +S G  G G   S G+G 
Sbjct: 1238 GFDGGLGTSAGFGGGPGTSTGFGGGLGTSA-----GFSGGLGTSAG-FGGGLVTSDGFGG 1291

Query: 2528 QGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS 2587
                          G G+  S        GS   +S+G  G GL  S GFG   ++S   
Sbjct: 1292 --------------GLGTNAS-------FGSTLGTSAGFSG-GLSTSDGFGSRPNASFDR 1329

Query: 2588 --SSYSQHGSGSGHSSGYGQHGSRSGQSSRGERH--GSSSGSSSHYG-QHGSGSRQSSGH 2642
              S+    GSGS  S+G+    S S   S G     G S G S+  G   G  +   SG 
Sbjct: 1330 GLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGG 1389

Query: 2643 GRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRG 2682
               G+G G  P+ G  G G G S+S G  GSG+    + G
Sbjct: 1390 PSTGAGFGGGPNTGA-GFGGGPSTSAG-FGSGAASLGACG 1427



 Score =  102 bits (254), Expect = 5e-21
 Identities = 215/824 (26%), Positives = 302/824 (36%), Gaps = 133/824 (16%)

Query: 544  SRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSS 603
            SRG   + +R   S G     +G  SS G +  G G + G+    S S  ++     G  
Sbjct: 724  SRG---ASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFG-- 778

Query: 604  SGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRG 663
             G  ST     S +  S  C    +TS  S +    G     S+ +    S S   P   
Sbjct: 779  -GTLSTSSSFSSAASISFGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLST 837

Query: 664  RHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHS 723
                  G SS +G      G  S+      V   S+ FG  S    S+ +S   S  S S
Sbjct: 838  SATFSGGASSGFG------GTLSTTAGFSGVLSTSTSFG--SAPTTSTVFS---SALSTS 886

Query: 724  SGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSR-VRHG 782
            +G+       G  S S   G S   S S+G   S S    G     +G G + S  V  G
Sbjct: 887  TGF------GGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFG 940

Query: 783  SSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQG 842
             SS  S++ G    GT  +S C  ++      +GFG   + S    S   +++G   +  
Sbjct: 941  GSSSTSANFG----GTLSTSIC--FDGSPSTGAGFGGALNTSASFGSVLNTSTGFGGAMS 994

Query: 843  RHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQ 902
                  G  S+S     S G S S+G   SA +  +G G   S +    G        G 
Sbjct: 995  TSADFGGTLSTSVCFGGSPGTSVSFG---SALNTNAGYGGAVSTNTDFGGTLSTSVCFGG 1051

Query: 903  SPSYGR-HGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHG 961
            SPS     G     ++S G   S S   SG    S+    +  T  G G   S+S     
Sbjct: 1052 SPSTSAGFGGALNTNASFGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTS----A 1107

Query: 962  SRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGR-HGSGSGQ 1020
               G  S +   G +  +S  +G   S S  S G G HG+      +PS     GS S  
Sbjct: 1108 GFGGALSTAADFGGTPSNSIGFGAAPSTS-VSFG-GAHGTSLCFGGAPSTSLCFGSASNT 1165

Query: 1021 SSSYG-PYRSGSGWSSSRGP-YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQ 1078
            +  +G P  + + +S +  P +  G   S+G       S  ++G+G      G  +T   
Sbjct: 1166 NLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLS-TNAGFG------GGLNTSAG 1218

Query: 1079 HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQS 1138
             G   G S+     G S G S+S G  G G   S+G+G    G G S G G         
Sbjct: 1219 FGGGLGTSA-----GFSGGLSTSSGFDG-GLGTSAGFG---GGPGTSTGFG--------- 1260

Query: 1139 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS 1198
                      G  +S+G  G GLG S+GFG      G   +    G G G ++ +G    
Sbjct: 1261 ---------GGLGTSAGFSG-GLGTSAGFG------GGLVTSDGFGGGLGTNASFG---- 1300

Query: 1199 RSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQ-----GSGSGHSPSRGRHGSGLG 1253
                S+ G   G S G S+     G GSR ++   R      G GSG + S G       
Sbjct: 1301 ----STLGTSAGFSGGLST---SDGFGSRPNASFDRGLSTIIGFGSGSNTSTG------- 1346

Query: 1254 HSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQH 1313
                 G+  + +G S         SG SS+ G           +S   S    FCS    
Sbjct: 1347 ---FTGEPSTSTGFS---------SGPSSIVG-----------FSGGPSTGVGFCSGPST 1383

Query: 1314 GSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSG 1357
               SG  ST    G      + +   G G S S+G+G   A  G
Sbjct: 1384 SGFSGGPSTGAGFGGGPNTGAGF---GGGPSTSAGFGSGAASLG 1424



 Score =  102 bits (254), Expect = 5e-21
 Identities = 201/767 (26%), Positives = 283/767 (36%), Gaps = 87/767 (11%)

Query: 429  RGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHS 488
            RG+ +    S G   +  G  SSSG +  G G + G     S+S  ++     G     S
Sbjct: 725  RGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTS 784

Query: 489  SGHGQHGSRS-GQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGR 547
            S      S S G +       SS  S S  G   + +  S G S   SG   + +   G 
Sbjct: 785  SSFSSAASISFGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGG 844

Query: 548  HES--GSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSS- 604
              S  G   S++ G  G  S  +S      + +  SS L         S+G+G   S+S 
Sbjct: 845  ASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFSSAL-------STSTGFGGILSTSV 897

Query: 605  ---GHSSTHGQHGSTSGQSSSCGQHGATS----GQSSSHGQHGSGSSQSSRYGQQGSGSG 657
               G  S+ G  G T   S   G    TS    G  S+    G  SS S+ +G   S S 
Sbjct: 898  CFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSI 957

Query: 658  QSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHG 717
                    G+ FG            G  +++   GSV   S+GFG     G  S  +  G
Sbjct: 958  CFDGSPSTGAGFG------------GALNTSASFGSVLNTSTGFG-----GAMSTSADFG 1000

Query: 718  SGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPS 777
               S S  +       G    S   GS+   ++ YG   S +    G        G SPS
Sbjct: 1001 GTLSTSVCF------GGSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPS 1054

Query: 778  RVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGH 837
                    G  +++   G   S S+S     S S   SG      G G  +S      G 
Sbjct: 1055 --TSAGFGGALNTNASFGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGA 1112

Query: 838  FSSQGRHGSTSGQSSSSGQHDSSS-------GQSSSYGQHESASHHASGRGRHGSGSGQS 890
             S+    G T   S   G   S+S       G S  +G   S S             G  
Sbjct: 1113 LSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLCFGGAPSTSLCFGSASNTNLCFGGP 1172

Query: 891  PGHGQRGSGSGQSPSYGRHGSGSGRSSSSG-RHGSGSGQSSGFGHKSSSGQSSGYTQHGS 949
            P      SG+  SPS+       G S+S+G   G+G   ++GFG       S+G+   G 
Sbjct: 1173 PSTSACFSGA-TSPSF-----CDGPSTSTGFSFGNGLSTNAGFG--GGLNTSAGF---GG 1221

Query: 950  GSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 1009
            G G S+ +      SG  S S       G+S+ +G  G G+    G G  G+ +G S   
Sbjct: 1222 GLGTSAGF------SGGLSTSSGFDGGLGTSAGFG-GGPGTSTGFGGGL-GTSAGFSGGL 1273

Query: 1010 SRGRHGSGSGQSSSYGPYRSGSGWSSSRG-PYESGSGHSSGLGHRESRSGQSSGYGQHGS 1068
                 G G G  +S G +  G G ++S G    + +G S GL         S G+G   +
Sbjct: 1274 GTSA-GFGGGLVTSDG-FGGGLGTNASFGSTLGTSAGFSGGL-------STSDGFGSRPN 1324

Query: 1069 SSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGH 1128
            +S         G  SG ++S G     +G+ S+     SG S   G+   G  +G     
Sbjct: 1325 ASFDRGLSTIIGFGSGSNTSTG----FTGEPSTSTGFSSGPSSIVGFS-GGPSTGVGFCS 1379

Query: 1129 GQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 1175
            G   SG    PS G  G G G ++ +G  G G   S+GFG   +S G
Sbjct: 1380 GPSTSGFSGGPSTGA-GFGGGPNTGAG-FGGGPSTSAGFGSGAASLG 1424



 Score =  102 bits (254), Expect = 5e-21
 Identities = 185/718 (25%), Positives = 262/718 (36%), Gaps = 69/718 (9%)

Query: 1836 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 1895
            G+ +    S G   S +G  SSSG    G G + G     S+S+ ++     G     SS
Sbjct: 726  GASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSS 785

Query: 1896 SYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1955
            S+    S S   +       SS +S S+G     S    G G   S SG   + +    G
Sbjct: 786  SFSSAASISFGCAHSTSTSFSSEASISFGGMPCTSASFSG-GVSSSFSGPLSTSATFSGG 844

Query: 1956 SGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSS----G 2011
            + SG   +       SG  S+   + S    S+      S    S+G+G   S+S    G
Sbjct: 845  ASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFS---SALSTSTGFGGILSTSVCFGG 901

Query: 2012 HSSTHGQHGSASGQSSSCGQHGASS----GQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG 2067
              S+ G  G     S   G    +S    G  S+    G  SS S+ +G   S S    G
Sbjct: 902  SPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDG 961

Query: 2068 HGQRGSGS----RQSPSYGRHGSGS----GRSSSSGQHGPGLGESSGFGHHESSSGQSSS 2119
                G+G       S S+G   + S    G  S+S   G  L  S  FG    S G S S
Sbjct: 962  SPSTGAGFGGALNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFG---GSPGTSVS 1018

Query: 2120 YSQHGSGSGHSSGYGQHGSRS----GQSSRGERHGSSSGSSSRYG-----QHGSGSRQSS 2170
            +   GS    ++GYG   S +    G  S     G S  +S+ +G         G   S+
Sbjct: 1019 F---GSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVST 1075

Query: 2171 GHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHES- 2229
                 G+ S  +   G   +  G   +        G  S+   +     +S  FG   S 
Sbjct: 1076 SASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPST 1135

Query: 2230 ----GSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST----GQSSSHGQHGS 2281
                G  H ++    G+ S   C     GS S  +  F    S++    G +S     G 
Sbjct: 1136 SVSFGGAHGTSLCFGGAPSTSLC----FGSASNTNLCFGGPPSTSACFSGATSPSFCDGP 1191

Query: 2282 GSSQSSSYGQ-----QGSGSGQSPSRGRHGSGSGHSSSYG-----QHGSGSGWSSSSGRH 2331
             +S   S+G       G G G + S G  G G G S+ +        G   G  +S+G  
Sbjct: 1192 STSTGFSFGNGLSTNAGFGGGLNTSAG-FGGGLGTSAGFSGGLSTSSGFDGGLGTSAG-F 1249

Query: 2332 GSGSGQSSGFGHHESSSWQSSG--YTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGS 2389
            G G G S+GFG    +S   SG   T  G G G  +S    G     +S G   G+S+G 
Sbjct: 1250 GGGPGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGF 1309

Query: 2390 SSSYG-QHGSGSRQSLGHGQH-----GSGSGQSPSPS-RGRHGSGSGQSSSYSPYGSGSG 2442
            S       G GSR +    +      G GSG + S    G   + +G SS  S     SG
Sbjct: 1310 SGGLSTSDGFGSRPNASFDRGLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSG 1369

Query: 2443 WSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG 2500
              S+   + SG   S   G   + +G   G        G  ST    GS +    +CG
Sbjct: 1370 GPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPSTSAGFGSGAASLGACG 1427



 Score =  102 bits (254), Expect = 5e-21
 Identities = 211/762 (27%), Positives = 281/762 (36%), Gaps = 98/762 (12%)

Query: 319  SSSHGQHGSGSSYSY-----SRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSS 373
            +S+      G+S S+     S G +  G G T G     S S  ++     G     SSS
Sbjct: 727  ASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSSS 786

Query: 374  QGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGS 433
                 S S   + S     SS  S S+G     S   SG G  SS SG           S
Sbjct: 787  FSSAASISFGCAHSTSTSFSSEASISFGGMPCTSASFSG-GVSSSFSGPL---------S 836

Query: 434  GQSPSSGQHGTGFGRSSSSGPYVSG-SGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHG 492
              +  SG   +GFG + S+    SG    S+ FG   ++S      T   S    S+G G
Sbjct: 837  TSATFSGGASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTS------TVFSSALSTSTGFG 890

Query: 493  QHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGS 552
                  G  S     G S  SS S+G   S S    G     +G G + S S      G 
Sbjct: 891  ------GILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTS---VSFGG 941

Query: 553  RQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRS---GQSSGYGQHGSSS----G 605
              S+S    G  S      G   +G+G    L    S       S+G+G   S+S    G
Sbjct: 942  SSSTSANFGGTLSTSICFDGSPSTGAGFGGALNTSASFGSVLNTSTGFGGAMSTSADFGG 1001

Query: 606  HSSTHGQHGSTSGQSSSCGQ----HGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPS 661
              ST    G + G S S G     +    G  S++   G   S S  +G   S S     
Sbjct: 1002 TLSTSVCFGGSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGG 1061

Query: 662  RGRHGSDFGHSSSYGQHGSG--------SGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGY 713
                 + FG + S     SG        SG   +N   G     S+GFG     G  S  
Sbjct: 1062 ALNTNASFGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFG-----GALSTA 1116

Query: 714  SQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSS---SGLSSSYGQHGSGSHQSSGHGRQGS 770
            +  G   S+S G+    S S   S    HG+S    G  S+    GS S+ +   G   S
Sbjct: 1117 ADFGGTPSNSIGFGAAPSTS--VSFGGAHGTSLCFGGAPSTSLCFGSASNTNLCFGGPPS 1174

Query: 771  GSGHSPSRVRHGSSSGHSSSHG-QHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYS 829
             S             G S+S G   G+G S ++  G    G   ++GF     G G G S
Sbjct: 1175 TSACFSGATSPSFCDGPSTSTGFSFGNGLSTNAGFG---GGLNTSAGF-----GGGLGTS 1226

Query: 830  QHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQ 889
              G + G  +S G  G     +   G   +S+G     G     S         G G   
Sbjct: 1227 A-GFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVT 1285

Query: 890  SPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQ--- 946
            S G    G G G + S+     GS   +S+G  G G   S GFG + ++    G +    
Sbjct: 1286 SDGF---GGGLGTNASF-----GSTLGTSAGFSG-GLSTSDGFGSRPNASFDRGLSTIIG 1336

Query: 947  HGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQS 1006
             GSGS  S+ +      +G+ S S   G SSG SS  G  G G    +G     S SG S
Sbjct: 1337 FGSGSNTSTGF------TGEPSTST--GFSSGPSSIVGFSG-GPSTGVGFCSGPSTSGFS 1387

Query: 1007 PSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSS 1048
              PS G  G G G ++  G    G G S+S G    GSG +S
Sbjct: 1388 GGPSTGA-GFGGGPNTGAG---FGGGPSTSAG---FGSGAAS 1422



 Score =  100 bits (250), Expect = 2e-20
 Identities = 200/776 (25%), Positives = 284/776 (36%), Gaps = 102/776 (13%)

Query: 212  SGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGE 271
            +  +S+N     G+   +GFS   S S   +  S  G   G    +G   S S   S   
Sbjct: 714  NADASTNVNFSRGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSN-T 772

Query: 272  RHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSY 331
               S  G+ S+     S +  S G     S S  S + +  G         G   + +S+
Sbjct: 773  ASISFGGTLSTSSSFSSAASISFGCAHSTSTSFSSEASISFG---------GMPCTSASF 823

Query: 332  SYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHG 391
            S          G +S F    S S   SG +  G G   S++ G     SG  S+S   G
Sbjct: 824  S---------GGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAG----FSGVLSTSTSFG 870

Query: 392  SSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGS-------GQSPSSGQHGT 444
            S+   S+ +    S S    G    S   G SP       G+       G SP +    T
Sbjct: 871  SAPTTSTVFSSALSTSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTS---T 927

Query: 445  GFGRS-SSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGH--------------SS 489
            GFG + S+S  +   S  S+ FG   S+S    G    G+G G               S+
Sbjct: 928  GFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPSTGAGFGGALNTSASFGSVLNTST 987

Query: 490  GHGQHGSRS----GQSSRGERQGSSAGSSSSYGQH-----GSGSRQSLGHSRHGSGS--- 537
            G G   S S    G  S     G S G+S S+G       G G   S      G+ S   
Sbjct: 988  GFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSV 1047

Query: 538  --GQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSS 595
              G SPS S G   + +  +S      +G   S+S     + S  +   G   +  G   
Sbjct: 1048 CFGGSPSTSAGFGGALNTNAS------FGCAVSTSASFSGAVSTSACFSGAPITNPGFGG 1101

Query: 596  GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSG 655
             +       G  ST    G T   S+S G   A S   S  G HG+    S  +G   S 
Sbjct: 1102 AFSTSAGFGGALSTAADFGGTP--SNSIGFGAAPSTSVSFGGAHGT----SLCFGGAPST 1155

Query: 656  SGQSPSRGRHGSDFGHSSSYGQHGSGSGWSS-SNGPHGSVSGQSSGFGHKSGSGQSSGYS 714
            S    S       FG   S     SG+   S  +GP       S+GF   +G   ++G+ 
Sbjct: 1156 SLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGP-----STSTGFSFGNGLSTNAGF- 1209

Query: 715  QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGH 774
              G G + S+G+   G   G S+     G S GLS+S G  G     +   G  G+ +G 
Sbjct: 1210 --GGGLNTSAGF---GGGLGTSA-----GFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGF 1259

Query: 775  SPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSA 834
                      SG   +    G G   S   G    G G  + FG    G+  G+S   S 
Sbjct: 1260 GGGLGTSAGFSGGLGTSAGFGGGLVTSDGFG---GGLGTNASFGS-TLGTSAGFSGGLST 1315

Query: 835  SGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRH-GSGSGQSPG- 892
            S  F S+       G S+  G    S+  +   G+  +++  +SG     G   G S G 
Sbjct: 1316 SDGFGSRPNASFDRGLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSGGPSTGV 1375

Query: 893  ---HGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYT 945
                G   SG    PS G  G G G ++ +G  G G   S+GFG  ++S  + G++
Sbjct: 1376 GFCSGPSTSGFSGGPSTGA-GFGGGPNTGAG-FGGGPSTSAGFGSGAASLGACGFS 1429



 Score = 95.9 bits (237), Expect = 5e-19
 Identities = 204/782 (26%), Positives = 282/782 (36%), Gaps = 100/782 (12%)

Query: 896  RGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYT-QHGSGSGHS 954
            RG+ +    S G   S +G  SSSG    G G + G    +S+  S+  +   G     S
Sbjct: 725  RGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTS 784

Query: 955  SSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH 1014
            SS+    S S   + S     SS +S S+G     S    G G   S SG   + +    
Sbjct: 785  SSFSSAASISFGCAHSTSTSFSSEASISFGGMPCTSASFSG-GVSSSFSGPLSTSATFSG 843

Query: 1015 GSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSS---- 1070
            G+ SG   +       SG  S+   + S    S+      S    S+G+G   S+S    
Sbjct: 844  GASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFS---SALSTSTGFGGILSTSVCFG 900

Query: 1071 GHSSTHGQHGSTSGQSSSCGQHGASS----GQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 1126
            G  S+ G  G T   S   G    +S    G  S+    G  SS S+ +G   S S    
Sbjct: 901  GSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFD 960

Query: 1127 GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG 1186
            G    G+G              G  ++S   GS L  S+GFG      G  S+ +  G  
Sbjct: 961  GSPSTGAGF------------GGALNTSASFGSVLNTSTGFG------GAMSTSADFGGT 1002

Query: 1187 SGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRG 1246
               S  +G      G        GS+  +++ YG   S +    G        G SPS  
Sbjct: 1003 LSTSVCFG------GSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTS 1056

Query: 1247 RHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGH 1306
              G G G  +++   G     S+S     S S   S  G   +  G   A+S      G 
Sbjct: 1057 A-GFG-GALNTNASFGCAVSTSASFSGAVSTSACFS--GAPITNPGFGGAFSTSAGFGGA 1112

Query: 1307 FCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGS--GQSPSRGR 1364
              +    G T   S  F   G++   S S+G            G HG     G +PS   
Sbjct: 1113 LSTAADFGGTPSNSIGF---GAAPSTSVSFG------------GAHGTSLCFGGAPSTSL 1157

Query: 1365 -HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGH 1423
              GS S  +  +G   S S   S +       G S+  G     S+ +   T  G G G 
Sbjct: 1158 CFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGF----SFGNGLSTNAGFGGGL 1213

Query: 1424 SSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGR 1483
            ++S    G        G   G S G S+S G  G      LG     +G G  P  S G 
Sbjct: 1214 NTSAGFGGGL------GTSAGFSGGLSTSSGFDGG-----LGTS---AGFGGGPGTSTG- 1258

Query: 1484 HGSGSGQSSSYSP-YGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGH 1542
             G G G S+ +S   G+ +G+    G   +      GLG   + +   S  G     SG 
Sbjct: 1259 FGGGLGTSAGFSGGLGTSAGFG---GGLVTSDGFGGGLG---TNASFGSTLGTSAGFSGG 1312

Query: 1543 SSTHGQHGSTSGQSSSCGQH---GASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHG 1599
             ST    GS    S   G     G  SG ++S G  G  S+ S+G+    S      G  
Sbjct: 1313 LSTSDGFGSRPNASFDRGLSTIIGFGSGSNTSTGFTGEPST-STGFSSGPSSIVGFSGGP 1371

Query: 1600 QRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH 1659
              G G    PS    G   G S+ +G  G G    +GFG   S+S         G GSG 
Sbjct: 1372 STGVGFCSGPSTS--GFSGGPSTGAG-FGGGPNTGAGFGGGPSTSA--------GFGSGA 1420

Query: 1660 SS 1661
            +S
Sbjct: 1421 AS 1422



 Score = 82.4 bits (202), Expect = 6e-15
 Identities = 174/652 (26%), Positives = 249/652 (38%), Gaps = 63/652 (9%)

Query: 2202 GSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS 2261
            G+ +    S G   S +G  S  G    G G +   +   S S    +    G T   SS
Sbjct: 726  GASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSS 785

Query: 2262 TFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS-GQSPSRGRHGSGSGHSSSYGQHGS 2320
            +F    S +         G   S S+S+  + S S G  P      SG G SSS+     
Sbjct: 786  SFSSAASIS--------FGCAHSTSTSFSSEASISFGGMPCTSASFSG-GVSSSF----- 831

Query: 2321 GSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRG 2380
             SG  S+S     G+  SSGFG   S++   SG     +  G + +     S +  +S G
Sbjct: 832  -SGPLSTSATFSGGA--SSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFSSALSTSTG 888

Query: 2381 ERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS------GQSSSY 2434
               G    +S  +G   S S    G        G SP  S G  G+ S      G SS+ 
Sbjct: 889  --FGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTS 946

Query: 2435 SPYGSGSGWSSS-RGPYESGSGHSSGLGHRESRSG---QSSGYGQHGSSS----GHSSTH 2486
            + +G     S    G   +G+G    L    S       S+G+G   S+S    G  ST 
Sbjct: 947  ANFGGTLSTSICFDGSPSTGAGFGGALNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTS 1006

Query: 2487 GQHGSTSGQSSSCGQ----HGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 2542
               G + G S S G     +    G  S++   G   S S  +G  GS S  +   G   
Sbjct: 1007 VCFGGSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFG--GSPSTSAGFGGALN 1064

Query: 2543 SGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS----GQSSSYSQHGSGSG 2598
            + +    +     S SG  S+S         + GFG   S+S    G  S+ +  G    
Sbjct: 1065 TNASFGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPS 1124

Query: 2599 HSSGYGQHGSRSGQSSRGERHGSS---SGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSR 2655
            +S G+G   S S   S G  HG+S    G+ S     GS S  +   G   S S      
Sbjct: 1125 NSIGFGAAPSTS--VSFGGAHGTSLCFGGAPSTSLCFGSASNTNLCFGGPPSTSACFSGA 1182

Query: 2656 GRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSG 2715
                   G S+S G    G+G S++ G +   L  S+ FG    G G S+ +S   S S 
Sbjct: 1183 TSPSFCDGPSTSTG-FSFGNGLSTNAG-FGGGLNTSAGFG---GGLGTSAGFSGGLSTSS 1237

Query: 2716 HFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRH 2775
             F   G  G+++G        G+STG     G  G+ +  S G G      G  ++    
Sbjct: 1238 GF--DGGLGTSAGFGGG---PGTSTGFG---GGLGTSAGFSGGLGTSAGFGGGLVTSDGF 1289

Query: 2776 GSGSGQSSSYGQH-GSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGS 2826
            G G G ++S+G   G+ +G S G S       +   S+ +G S   G  SGS
Sbjct: 1290 GGGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDRGLSTIIGFGSGS 1341



 Score = 66.2 bits (160), Expect = 4e-10
 Identities = 129/510 (25%), Positives = 185/510 (36%), Gaps = 54/510 (10%)

Query: 130  SSWSAGENDSYSRNVRGSLKP-----GTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNS 184
            +S S G + S S N  G+L       G+ S         + S    S    S+ +G   S
Sbjct: 935  TSVSFGGSSSTSANFGGTLSTSICFDGSPSTGAGFGGALNTSASFGSVLNTSTGFGGAMS 994

Query: 185  DSHQSSGR--------GQCGS----GSGQSPNYGQHGSGS------GQSSSNDTHGSGSG 226
             S    G         G  G+    GS  + N G  G+ S      G  S++   G    
Sbjct: 995  TSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPS 1054

Query: 227  QSSGFSQHKSSSGQ-----SSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSS 281
             S+GF    +++       S+  S  G+ S  +   G   +  G            G+ S
Sbjct: 1055 TSAGFGGALNTNASFGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALS 1114

Query: 282  SYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSG---SGHSSSHGQHGSGSSYSYSRGHY 338
            +    G     S+G G   S S        HG+     G  S+    GS S+ +   G  
Sbjct: 1115 TAADFGGTPSNSIGFGAAPSTSVSFGG--AHGTSLCFGGAPSTSLCFGSASNTNLCFGGP 1172

Query: 339  ESGSGQTSGFGQHE--SGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQ 396
             S S   SG        G   S+G+S    G+G S++ G  G  +  A   G  G+S+  
Sbjct: 1173 PSTSACFSGATSPSFCDGPSTSTGFS---FGNGLSTNAGFGGGLNTSAGFGGGLGTSAGF 1229

Query: 397  SSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSS-SGPY 455
            S   G   ++S    G G  S+G G  PG    G G G   S+G  G G G S+   G  
Sbjct: 1230 S---GGLSTSSGFDGGLGT-SAGFGGGPGTST-GFGGGLGTSAGFSG-GLGTSAGFGGGL 1283

Query: 456  VSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSS 515
            V+  G+  G G + S             G   S G G   + S         G  +GS++
Sbjct: 1284 VTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDRGLSTIIGFGSGSNT 1343

Query: 516  SYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYE 575
            S G  G  S  +   S   S  G S  PS G        +S     G+  G S+  G   
Sbjct: 1344 STGFTGEPSTSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTS-----GFSGGPSTGAG--- 1395

Query: 576  SGSGHSSGLGHQESRSGQSSGYGQHGSSSG 605
             G G ++G G     S  S+G+G   +S G
Sbjct: 1396 FGGGPNTGAGFGGGPS-TSAGFGSGAASLG 1424



 Score = 65.9 bits (159), Expect = 6e-10
 Identities = 94/347 (27%), Positives = 128/347 (36%), Gaps = 45/347 (12%)

Query: 212  SGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHS-----SGYGQHGSR--- 263
            SG   +N   G     S+GF    S++    G   +  G G +     S  G HG+    
Sbjct: 1090 SGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLCF 1149

Query: 264  SGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPS-----------HVRH 312
             G  S      S+S ++  +G  G  S  +   G         PS               
Sbjct: 1150 GGAPSTSLCFGSASNTNLCFG--GPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNA 1207

Query: 313  GSGSGHSSSHGQHGS-GSSYSYSRG-----HYESGSGQTSGFGQHESGSGQSSGYSKH-G 365
            G G G ++S G  G  G+S  +S G      ++ G G ++GFG    G G S+G+    G
Sbjct: 1208 GFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFG---GGPGTSTGFGGGLG 1264

Query: 366  SGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPG 425
            + +G S   G      G   +S   G     ++S+G     S   SG    S G G  P 
Sbjct: 1265 TSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPN 1324

Query: 426  HGQR-------GSGSGQSPSSGQHG---TGFGRSSSSGPYVSGSGYSS---GFGHHESSS 472
                       G GSG + S+G  G   T  G SS     V  SG  S   GF    S+S
Sbjct: 1325 ASFDRGLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTS 1384

Query: 473  EHSSG-YTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYG 518
              S G  T  G G G ++G G  G  S  +  G    S      SYG
Sbjct: 1385 GFSGGPSTGAGFGGGPNTGAGFGGGPSTSAGFGSGAASLGACGFSYG 1431



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 87/311 (27%), Positives = 112/311 (36%), Gaps = 39/311 (12%)

Query: 2541 RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS----------GQSSSY 2590
            RG+ +R   S G   S +G  SSSG    G G + G     S+S          G  S+ 
Sbjct: 725  RGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTS 784

Query: 2591 SQHGSGSGHSSGYGQHGSRSGQSSRGERHGS--------SSGSSSHYGQHGSGSRQSSGH 2642
            S   S +  S G     S S  S      G         S G SS +    S S   SG 
Sbjct: 785  SSFSSAASISFGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGG 844

Query: 2643 GRQGSGSGQSPSRGRHGSGLGHSSSHGQHGS-----GSGRSSSRGPYESRLGHSSVFGQH 2697
               G G   S + G  G  L  S+S G   +      S  S+S G +   L  S  FG  
Sbjct: 845  ASSGFGGTLSTTAGFSGV-LSTSTSFGSAPTTSTVFSSALSTSTG-FGGILSTSVCFGGS 902

Query: 2698 ESGSG-HSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQS 2756
             S SG      S      G  C+    G T   S +F   G S+  S+++G   S S   
Sbjct: 903  PSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSF---GGSSSTSANFGGTLSTSICF 959

Query: 2757 SGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQ-HGSGSGQSSGYSQHGSGSGQDGYSYCKG 2815
             G    GAG G +L+          S+S+G    + +G     S      G    S C G
Sbjct: 960  DGSPSTGAGFGGALN---------TSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFG 1010

Query: 2816 GSNHDGGSSGS 2826
            GS     S GS
Sbjct: 1011 GSPGTSVSFGS 1021


>gi|239744892 PREDICTED: hypothetical protein XP_002344252 [Homo
           sapiens]
          Length = 557

 Score =  111 bits (278), Expect = 9e-24
 Identities = 121/503 (24%), Positives = 148/503 (29%), Gaps = 28/503 (5%)

Query: 311 RHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGH 370
           +HG      S    H    S       +     +  G  +H     +  G  KHG     
Sbjct: 51  KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSR 110

Query: 371 SSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRG 430
                +HG    +     +HG +         H  A    SG   H  G   SP  G R 
Sbjct: 111 LIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTH--GDAPSPLSGDRT 168

Query: 431 SGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYS--SGFGHHESSSEHSSGYTQHGSGSGHS 488
            G   SP SG    G   S  SG    G   S   G   H  +    SG  +HG      
Sbjct: 169 HGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSRL 228

Query: 489 SGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRH 548
            G   HG    + S     G +         HG    +  G   HG     +PS   G  
Sbjct: 229 GGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGD----APSRLGGDR 284

Query: 549 ESGSRQSSSYGPHGYGSGRSSSRGPYESGS-----GHSSGLGHQESRSGQSSGYGQHGSS 603
             G   S   G   +G   S   G    G      G     G   SR      +G   S 
Sbjct: 285 THGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSR 344

Query: 604 SGHSSTHGQ----------HGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQG 653
            G   THG           HG    + S    HG    + S    HG   S+ S  G + 
Sbjct: 345 LGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLS--GDRT 402

Query: 654 SGSGQSPSRG--RHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFG-HKSGSGQS 710
            G   SP  G   HG      S    HG      S +  HG       G   H       
Sbjct: 403 HGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPL 462

Query: 711 SGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGS 770
           SG   HG   S  SG R HG    + SR  +HG +    S    HG      SG    G 
Sbjct: 463 SGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSGDRTHGD 522

Query: 771 GSGHSPSRVRHGSSSGHSSSHGQ 793
                    +HG +    S   Q
Sbjct: 523 PLSRLSGDRKHGDAPSPLSGDHQ 545



 Score =  110 bits (276), Expect = 2e-23
 Identities = 122/528 (23%), Positives = 157/528 (29%), Gaps = 36/528 (6%)

Query: 959  QHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS 1018
            +HG      S    H           +H     + +G  +HG     +PS   G    G 
Sbjct: 51   KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGD----APSRLIGDRKHGD 106

Query: 1019 GQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQS--SGYGQHGSSSGHSSTH 1076
              S   G  + G   S   G  + G   S  +G R      S  SG   HG +    S  
Sbjct: 107  APSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGD 166

Query: 1077 GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 1136
              HG      S    HG +  + S   +HG   S+  G    G           R SG R
Sbjct: 167  RTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAP-------SRLSGDR 219

Query: 1137 QSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQH 1196
                  +HG    R      HG      SG   H  +  +      HG      SG   H
Sbjct: 220  ------KHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTH 273

Query: 1197 GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSS 1256
            G    +      HG +         HG    + SG    G     +PSR      LG   
Sbjct: 274  GDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGD----APSR------LGGDR 323

Query: 1257 SHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGST 1316
            +HG+  S      + G   SR G     G   S  G       HG           HG  
Sbjct: 324  THGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRT---HGDAPSRLSGDRTHGDA 380

Query: 1317 SGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYG 1376
              + S     G +  + S     G   S   G   HG    +      HG    H S   
Sbjct: 381  PSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDR 440

Query: 1377 QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQ 1436
             HG           HG      SG   H  +  + SG   HG      S   +HG     
Sbjct: 441  THGDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSP 500

Query: 1437 SSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH 1484
             S    HG +    S    HG    +  G  +H    G +PSP  G H
Sbjct: 501  LSGDCTHGDAPSPLSGDRTHGDPLSRLSGDRKH----GDAPSPLSGDH 544



 Score =  108 bits (271), Expect = 6e-23
 Identities = 119/514 (23%), Positives = 147/514 (28%), Gaps = 26/514 (5%)

Query: 725  GYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSS 784
            G RKHG      S    H           +H     +  G  + G          +HG +
Sbjct: 48   GDRKHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDA 107

Query: 785  SGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRH 844
                    +HG   S     G  + G   +   G            HG A    S    H
Sbjct: 108  PSRLIGDRKHGDAPS--RLIGDRKHGDAPSPLIGDRT---------HGDAPSRLSGDRTH 156

Query: 845  GSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSP 904
            G      S    H  +    S    H  A    SG  +HG    +  G    G    +  
Sbjct: 157  GDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLS 216

Query: 905  SYGRHGSGSGRSSSSGRHGSGSGQSSG-FGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSR 963
               +HG    R      HG    + SG   H  +  +  G   HG      S    HG  
Sbjct: 217  GDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDA 276

Query: 964  SGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSS 1023
              +      HG +         HG    +  G   H    G +PS   G    G   S  
Sbjct: 277  PSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTH----GDAPSRLGGDRTHGEAPSRL 332

Query: 1024 YGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQS--SGYGQHGSSSGHSSTHGQHGS 1081
             G    G   S   G    G   S   G R      S  SG   HG +    S    HG 
Sbjct: 333  SGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGD 392

Query: 1082 TSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGH--GQRGSGSRQSP 1139
               + S    HG +         HG   S+ SG        G +P H  G R  G   SP
Sbjct: 393  APSRLSGDRTHGDAPSPLGGDRTHGDALSRLSG----DRTHGDAPSHLSGDRTHGDAPSP 448

Query: 1140 SYGRHGSGSGRSSSSGQ--HGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHG 1197
              G    G   S  SG   HG  L   SG   H     + S   +HG      SG   HG
Sbjct: 449  LGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHG 508

Query: 1198 SRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSG 1231
                  S    HG      S   +HG      SG
Sbjct: 509  DAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPLSG 542



 Score =  108 bits (269), Expect = 1e-22
 Identities = 119/506 (23%), Positives = 147/506 (29%), Gaps = 15/506 (2%)

Query: 243 GYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSG 302
           G  +HG      SG   H           +HR +        +HG    + +G  + G  
Sbjct: 48  GDRKHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDA 107

Query: 303 SRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYS 362
             +     +HG          +HG   S       +     + SG   H       SG  
Sbjct: 108 PSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDR 167

Query: 363 KHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQ 422
            HG      S    HG    + S   +HG +  +      H  A    SG  +H  G   
Sbjct: 168 THGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKH--GDAP 225

Query: 423 SPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYS--SGFGHHESSSEHSSGYTQ 480
           S   G R  G   S  SG    G   S   G    G   S  SG   H  +     G   
Sbjct: 226 SRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRT 285

Query: 481 HGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQS 540
           HG       G   HG    + S     G +         HG    +  G   H    G +
Sbjct: 286 HGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTH----GDA 341

Query: 541 PSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQS--SGYG 598
           PS   G    G   S   G   +G   S   G    G   S   G +      S  SG  
Sbjct: 342 PSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDR 401

Query: 599 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQ 658
            HG +         HG    + S    HG      S    HG   S     G +  G   
Sbjct: 402 THGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLG--GDRTHGDAP 459

Query: 659 SPSRG--RHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSG-FGHKSGSGQSSGYSQ 715
           SP  G   HG      S    HG      S +  HG      SG   H       SG   
Sbjct: 460 SPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSGDRT 519

Query: 716 HGSGSSHSSGYRKHGSRSGQSSRSEQ 741
           HG   S  SG RKHG      S   Q
Sbjct: 520 HGDPLSRLSGDRKHGDAPSPLSGDHQ 545



 Score =  107 bits (267), Expect = 2e-22
 Identities = 121/528 (22%), Positives = 155/528 (29%), Gaps = 36/528 (6%)

Query: 1899 QHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS 1958
            +HG      S    H           +H     + +G  +HG     +PS   G    G 
Sbjct: 51   KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGD----APSRLIGDRKHGD 106

Query: 1959 GQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQS--SGYGQHGSSSGHSSTH 2016
              S   G    G   S   G  + G   S  +G R      S  SG   HG +    S  
Sbjct: 107  APSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGD 166

Query: 2017 GQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 2076
              HG A    S    HG +  + S   +HG   S+  G    G           R SG R
Sbjct: 167  RTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAP-------SRLSGDR 219

Query: 2077 QSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQH 2136
                  +HG    R      HG      SG   H  +  +      HG      SG   H
Sbjct: 220  ------KHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTH 273

Query: 2137 GSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSS 2196
            G    +      HG +         HG    + SG    G     +PSR       G   
Sbjct: 274  GDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGD----APSR------LGGDR 323

Query: 2197 SHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGST 2256
            +HG+  S      + G   SR G     G   S  G       HG           HG  
Sbjct: 324  THGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRT---HGDAPSRLSGDRTHGDA 380

Query: 2257 SGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYG 2316
              + S     G +  + S    HG   S        G    +      HG    H S   
Sbjct: 381  PSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDR 440

Query: 2317 QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQ 2376
             HG           HG      SG   H  +  + SG   HG      S   +HG     
Sbjct: 441  THGDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSP 500

Query: 2377 SSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH 2424
             S    HG +    S    HG    +  G  +H    G +PSP  G H
Sbjct: 501  LSGDCTHGDAPSPLSGDRTHGDPLSRLSGDRKH----GDAPSPLSGDH 544



 Score =  106 bits (264), Expect = 4e-22
 Identities = 123/530 (23%), Positives = 157/530 (29%), Gaps = 42/530 (7%)

Query: 1437 SSRGER-HGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS---------GQSPSPSRGRHGS 1486
            S RG+R HG +    S    H       +G  +H             G +PS   G    
Sbjct: 45   SYRGDRKHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKH 104

Query: 1487 GSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQS--SGYGQHGSSSGHSS 1544
            G   S        G   S   G  + G + S  +G R      S  SG   HG +    S
Sbjct: 105  GDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLS 164

Query: 1545 THGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSG 1604
                HG      S    HG +  + S   +HG   S+  G    G           R SG
Sbjct: 165  GDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAP-------SRLSG 217

Query: 1605 SRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYG 1664
             R      +HG    R      HG      SG   H  +  +      HG      SG  
Sbjct: 218  DR------KHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDR 271

Query: 1665 QHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGH 1724
             HG    +      HG +         HG    + SG        G +PSR      LG 
Sbjct: 272  THGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTH----GDAPSR------LGG 321

Query: 1725 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHG 1784
              +HG+  S      + G   SR G     G   S  G       HG           HG
Sbjct: 322  DRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRT---HGDAPSRLSGDRTHG 378

Query: 1785 STSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSS 1844
                + S     G +  + S    HG   S        G    +      HG    H S 
Sbjct: 379  DAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSG 438

Query: 1845 YGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRS 1904
               HG           HG      SG   H  +  + SG   HG      S   +HG   
Sbjct: 439  DRTHGDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAP 498

Query: 1905 GQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH 1954
               S    HG +    S    HG    +  G  +H    G +PSP  G H
Sbjct: 499  SPLSGDCTHGDAPSPLSGDRTHGDPLSRLSGDRKH----GDAPSPLSGDH 544



 Score =  102 bits (253), Expect = 7e-21
 Identities = 118/534 (22%), Positives = 153/534 (28%), Gaps = 40/534 (7%)

Query: 376 QHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQ 435
           +HG T    S    H           +H  A     G  +H     +  G  + G    +
Sbjct: 51  KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSR 110

Query: 436 SPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHG 495
                +HG    R      +        G   H  +    SG   HG      SG   HG
Sbjct: 111 LIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHG 170

Query: 496 SRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQS 555
                 S     G +    S   +HG    +  G   HG     +PS   G  + G   S
Sbjct: 171 DAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGD----APSRLSGDRKHGDAPS 226

Query: 556 SSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGS 615
              G   +G   S   G    G           SR G    +G+  S      THG   S
Sbjct: 227 RLGGDRTHGDAPSRLSGDRTHGDA--------PSRLGGDRTHGEAPSRLSGDRTHGDAPS 278

Query: 616 TSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSY 675
             G   + G   +  G   +HG   S  S    +G   S  G   + G   S      ++
Sbjct: 279 RLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTH 338

Query: 676 GQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQ 735
           G   S  G   ++G   S  G      H     + SG   HG   S  SG R HG    +
Sbjct: 339 GDAPSRLGGDRTHGDAPSRLGGDRT--HGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSR 396

Query: 736 SSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHG 795
            S    HG +         HG    + SG    G    H      HG +         HG
Sbjct: 397 LSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHG 456

Query: 796 SGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSG 855
              S  S                        G   HG A    S    HG    + S   
Sbjct: 457 DAPSPLS------------------------GDRTHGDALSRLSGDRTHGDPLSRLSRDR 492

Query: 856 QHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRH 909
           +H  +    S    H  A    SG   HG    +    G R  G   SP  G H
Sbjct: 493 KHGDAPSPLSGDCTHGDAPSPLSGDRTHGDPLSRL--SGDRKHGDAPSPLSGDH 544



 Score =  100 bits (249), Expect = 2e-20
 Identities = 108/513 (21%), Positives = 139/513 (27%), Gaps = 21/513 (4%)

Query: 1860 RHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGS 1919
            +HG      SG   H        G  +H           +HG    +     +HG +   
Sbjct: 51   KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSR 110

Query: 1920 SSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGP 1979
                 +HG    + +G  +HG     +PSP  G    G   S   G    G   S   G 
Sbjct: 111  LIGDRKHGDAPSRLIGDRKHGD----APSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGD 166

Query: 1980 YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQS 2039
               G   S   G R            HG +    S   +HG A  +      HG +  + 
Sbjct: 167  RTHGDAPSPLSGDRT-----------HGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRL 215

Query: 2040 SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGP 2099
            S   +HG   S+  G    G    +  G    G    +      HG    R S    HG 
Sbjct: 216  SGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGD 275

Query: 2100 GLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRY 2159
                  G   H  +  +      HG      SG   HG    +      HG +    S  
Sbjct: 276  APSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGD 335

Query: 2160 GQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSS---SRGPYES 2216
              HG    +  G    G           HG      S    HG    R S   + G   S
Sbjct: 336  RTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPS 395

Query: 2217 RSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSH 2276
            R       G   S  G       HG           HG      S     G +       
Sbjct: 396  RLSGDRTHGDAPSPLGGDRT---HGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGD 452

Query: 2277 GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 2336
              HG   S  S     G    +      HG      S   +HG      S    HG    
Sbjct: 453  RTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPS 512

Query: 2337 QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQ 2369
              SG   H     + SG  +HG      S   Q
Sbjct: 513  PLSGDRTHGDPLSRLSGDRKHGDAPSPLSGDHQ 545



 Score = 99.4 bits (246), Expect = 5e-20
 Identities = 104/461 (22%), Positives = 131/461 (28%), Gaps = 21/461 (4%)

Query: 207 QHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQ 266
           +HG    +   +  HG    +  G  +H  +     G   HG      SG   HG     
Sbjct: 103 KHGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSP 162

Query: 267 SSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHG 326
            S    H  +    S    HG    +  G  + G    +      HG      S   +HG
Sbjct: 163 LSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHG 222

Query: 327 SGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASS 386
              S       +     + SG   H     +  G   HG      S    HG    +   
Sbjct: 223 DAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGG 282

Query: 387 SGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGF 446
              HG +  +      H  A    SG   H  G   S   G R  G   S  SG    G 
Sbjct: 283 DRTHGDAPSRLGGDRTHGDAPSRLSGDRTH--GDAPSRLGGDRTHGEAPSRLSGDRTHGD 340

Query: 447 GRSSSSGPYVSGSGYS--SGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRG 504
             S   G    G   S   G   H  +    SG   HG      SG   HG    + S  
Sbjct: 341 APSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGD 400

Query: 505 ERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYG 564
              G +         HG    +  G   H    G +PS   G    G   S   G   +G
Sbjct: 401 RTHGDAPSPLGGDRTHGDALSRLSGDRTH----GDAPSHLSGDRTHGDAPSPLGGDRTHG 456

Query: 565 SGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG 624
              S   G    G   S           + SG   HG      S   +HG      S   
Sbjct: 457 DAPSPLSGDRTHGDALS-----------RLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDC 505

Query: 625 QHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRH 665
            HG      S    HG   S+ S  G +  G   SP  G H
Sbjct: 506 THGDAPSPLSGDRTHGDPLSRLS--GDRKHGDAPSPLSGDH 544



 Score = 99.0 bits (245), Expect = 6e-20
 Identities = 104/494 (21%), Positives = 136/494 (27%), Gaps = 7/494 (1%)

Query: 824  SGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRH 883
            S +G  +HG      S    H           +H  +  +     +H  A     G  +H
Sbjct: 45   SYRGDRKHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKH 104

Query: 884  GSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSG-FGHKSSSGQSS 942
            G    +  G  + G    +     +HG           HG    + SG   H  +    S
Sbjct: 105  GDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLS 164

Query: 943  GYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 1002
            G   HG      S    HG    + S   +HG +         HG    +  G  +H   
Sbjct: 165  GDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKH--- 221

Query: 1003 SGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQS-- 1060
             G +PS   G    G   S   G    G   S   G    G   S   G R      S  
Sbjct: 222  -GDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRL 280

Query: 1061 SGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS 1120
             G   HG +         HG    + S    HG +  +      HG   S+ SG    G 
Sbjct: 281  GGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGD 340

Query: 1121 GSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSY 1180
               +  G    G    +      HG    R S    HG      SG   H  +  + S  
Sbjct: 341  APSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGD 400

Query: 1181 SQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSG 1240
              HG       G   HG    + S    HG +    S    HG       G    G    
Sbjct: 401  RTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPS 460

Query: 1241 HSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQH 1300
                   HG  L   S    HG    R S    +       S    H       S    H
Sbjct: 461  PLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSGDRTH 520

Query: 1301 GSGSGHFCSQGQHG 1314
            G          +HG
Sbjct: 521  GDPLSRLSGDRKHG 534



 Score = 99.0 bits (245), Expect = 6e-20
 Identities = 113/539 (20%), Positives = 151/539 (28%), Gaps = 41/539 (7%)

Query: 1062 GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG 1121
            G  +HG +    S    H           +H  +  +     +HG   S+  G  + G  
Sbjct: 48   GDRKHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDA 107

Query: 1122 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS 1181
              +  G  + G    +     +HG           HG      SG   H  +    S   
Sbjct: 108  PSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDR 167

Query: 1182 QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGH 1241
             HG      SG   HG    + S   +HG +         HG    + SG  + G     
Sbjct: 168  THGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGD---- 223

Query: 1242 SPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHG 1301
            +PSR      LG   +HG   S      + G   SR G     G+  S     S    HG
Sbjct: 224  APSR------LGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPS---RLSGDRTHG 274

Query: 1302 SGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPS 1361
                       HG    +       G +  + S     G   S+  G   HG    +   
Sbjct: 275  DAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSG 334

Query: 1362 RGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGS 1421
               HG           HG           HG    + SG   H  +  + SG   HG   
Sbjct: 335  DRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAP 394

Query: 1422 GHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR 1481
               S    HG           HG +    S    HG       G   H    G +PSP  
Sbjct: 395  SRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTH----GDAPSPLG 450

Query: 1482 GRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSG 1541
            G    G   S                 P     +H   L        + SG   HG    
Sbjct: 451  GDRTHGDAPS-----------------PLSGDRTHGDAL-------SRLSGDRTHGDPLS 486

Query: 1542 HSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 1600
              S   +HG      S    HG +    S    HG   S+ SG  + G       G  Q
Sbjct: 487  RLSRDRKHGDAPSPLSGDCTHGDAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPLSGDHQ 545



 Score = 99.0 bits (245), Expect = 6e-20
 Identities = 109/497 (21%), Positives = 143/497 (28%), Gaps = 24/497 (4%)

Query: 2317 QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQ 2376
            +HG      S    H        G   H  +  +  G  +HG          +HG    +
Sbjct: 51   KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSR 110

Query: 2377 SSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS---------GQSPSPSRGRHGSG 2427
                 +HG +        +HG      +G   HG            G +PSP  G    G
Sbjct: 111  LIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHG 170

Query: 2428 SGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQS--SGYGQHGSSSGHSST 2485
               S        G   S   G  + G   S   G R      S  SG  +HG +      
Sbjct: 171  DAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSRLGG 230

Query: 2486 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2545
               HG    + S    HG +  +      HG   S+ SG    G    +  G    G   
Sbjct: 231  DRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAP 290

Query: 2546 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2605
             +      HG    R S    HG       G   H  +  + S    HG       G   
Sbjct: 291  SRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRT 350

Query: 2606 HGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHS 2665
            HG    +      HG +    S    HG    + SG        G +PSR      L   
Sbjct: 351  HGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTH----GDAPSR------LSGD 400

Query: 2666 SSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGS 2725
             +HG   S  G   + G   SRL      G   S   H S    HG           HG 
Sbjct: 401  RTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPS---HLSGDRTHGDAPSPLGGDRTHGD 457

Query: 2726 TSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSY 2785
                 S     G +  + S     G   S+ S   +HG           HG      S  
Sbjct: 458  APSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSGD 517

Query: 2786 GQHGSGSGQSSGYSQHG 2802
              HG    + SG  +HG
Sbjct: 518  RTHGDPLSRLSGDRKHG 534



 Score = 98.6 bits (244), Expect = 8e-20
 Identities = 110/513 (21%), Positives = 144/513 (28%), Gaps = 22/513 (4%)

Query: 921  RHGSGSGQSSGFG-HKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGS 979
            +HG      SG   H+       G  +H           +HG    +     +HG +   
Sbjct: 51   KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSR 110

Query: 980  SSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGP 1039
                 +HG    + +G  +HG     +PSP  G    G   S   G    G   S   G 
Sbjct: 111  LIGDRKHGDAPSRLIGDRKHGD----APSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGD 166

Query: 1040 YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQS 1099
               G   S   G R            HG +    S   +HG    +      HG +  + 
Sbjct: 167  RTHGDAPSPLSGDRT-----------HGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRL 215

Query: 1100 SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGS 1159
            S   +HG   S+  G    G    +  G    G    +      HG    R S    HG 
Sbjct: 216  SGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGD 275

Query: 1160 GLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHY 1219
                  G   H  +  +      HG      SG   HG    +      HG +    S  
Sbjct: 276  APSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGD 335

Query: 1220 GQHGSGSRQSSG---HGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYES 1276
              HG    +  G   HG   S  G   + G   S L    +HG   S      + G   S
Sbjct: 336  RTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPS 395

Query: 1277 RSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSY 1336
            R       G   S  G       HG           HG      S     G +       
Sbjct: 396  RLSGDRTHGDAPSPLGGDRT---HGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGD 452

Query: 1337 GHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 1396
               G   S  SG   HG    +      HG      S   +HG      S    HG    
Sbjct: 453  RTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPS 512

Query: 1397 QSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQ 1429
              SG   H     + SG  +HG      S   Q
Sbjct: 513  PLSGDRTHGDPLSRLSGDRKHGDAPSPLSGDHQ 545



 Score = 98.6 bits (244), Expect = 8e-20
 Identities = 99/398 (24%), Positives = 124/398 (31%), Gaps = 17/398 (4%)

Query: 166 SGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYG--QHGSGSGQSSSNDTHGS 223
           SG        S   G++      S   G    G   S   G  +HG    +   + THG 
Sbjct: 151 SGDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGD 210

Query: 224 GSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSY 283
              + SG  +H  +  +  G   HG      SG   HG    +      H  +    S  
Sbjct: 211 APSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGD 270

Query: 284 GQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSG-SSYSYSRGHYESGS 342
             HG    +  G    G    +      HG      S    HG   S     R H E+ S
Sbjct: 271 RTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPS 330

Query: 343 GQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQ 402
            + SG   H     +  G   HG           HG    + S    HG +  + S    
Sbjct: 331 -RLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRT 389

Query: 403 HESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYS 462
           H  A    SG   H  G   SP  G R  G   S  SG    G   S  SG    G   S
Sbjct: 390 HGDAPSRLSGDRTH--GDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPS 447

Query: 463 --SGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQH 520
              G   H  +    SG   HG      SG   HG    + SR  + G +    S    H
Sbjct: 448 PLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTH 507

Query: 521 GSGSRQSLGHSRHG------SGS---GQSPSPSRGRHE 549
           G       G   HG      SG    G +PSP  G H+
Sbjct: 508 GDAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPLSGDHQ 545



 Score = 97.8 bits (242), Expect = 1e-19
 Identities = 110/514 (21%), Positives = 137/514 (26%), Gaps = 19/514 (3%)

Query: 2056 GRQGSGSGQSPGHGQRGSGSRQSPSYG--RHGSGSGRSSSSGQHGPGLGESSGFGHHESS 2113
            G +  G   SP  G R      SP  G  +H     R     +HG       G   H  +
Sbjct: 48   GDRKHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDA 107

Query: 2114 SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHG 2173
              +     +HG       G  +HG           HG +    S    HG      SG  
Sbjct: 108  PSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDR 167

Query: 2174 RQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 2233
              G           HG      S   +HG    R      +       S   +H      
Sbjct: 168  THGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSR 227

Query: 2234 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQG 2293
                  HG           HG    +       G +  + S    HG   S+       G
Sbjct: 228  LGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHG 287

Query: 2294 SGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 2353
                +      HG      S    HG           HG    + SG   H  +  +  G
Sbjct: 288  DAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGG 347

Query: 2354 YTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 2413
               HG           HG    + S    HG +    S    HG    +  G   HG   
Sbjct: 348  DRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGD-- 405

Query: 2414 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGY 2473
              +PSP  G    G   S        G   S   G    G   S   G R          
Sbjct: 406  --APSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRT--------- 454

Query: 2474 GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSG 2533
              HG +    S    HG    + S    HG    + S   +HG   S  SG      G  
Sbjct: 455  --HGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTH--GDA 510

Query: 2534 QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH 2567
             SP  G R  G   S   G    G   S  SG H
Sbjct: 511  PSPLSGDRTHGDPLSRLSGDRKHGDAPSPLSGDH 544



 Score = 96.3 bits (238), Expect = 4e-19
 Identities = 109/513 (21%), Positives = 143/513 (27%), Gaps = 21/513 (4%)

Query: 2031 QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGR 2090
            +HG +    S    H    S   G  +      +  G  + G    +     +HG    R
Sbjct: 51   KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSR 110

Query: 2091 SSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG 2150
                 +HG       G   H  +         HG      SG   HG      S    HG
Sbjct: 111  LIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHG 170

Query: 2151 SSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGR--- 2207
             +    S    HG    + SG  + G           HG      S   +HG    R   
Sbjct: 171  DAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSRLGG 230

Query: 2208 SSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEG 2267
              + G   SR       G   S  G    + +  S      + G   S  G   T     
Sbjct: 231  DRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAP 290

Query: 2268 SSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSS 2327
            S  G   +HG   S  S   ++G   S  G   +   HG      S    HG        
Sbjct: 291  SRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRT---HGEAPSRLSGDRTHGDAPSRLGG 347

Query: 2328 SGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSS 2387
               HG    +  G   H  +  + SG   HG      S    HG    + S    HG + 
Sbjct: 348  DRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAP 407

Query: 2388 GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSR 2447
                    HG    +  G   HG     +PS   G    G   S    P G       + 
Sbjct: 408  SPLGGDRTHGDALSRLSGDRTHGD----APSHLSGDRTHGDAPS----PLGGDRTHGDAP 459

Query: 2448 GPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSG 2507
             P      H   L        + SG   HG      S   +HG      S    HG +  
Sbjct: 460  SPLSGDRTHGDALS-------RLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPS 512

Query: 2508 QSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 2540
              S    HG   S+ SG  + G       G  Q
Sbjct: 513  PLSGDRTHGDPLSRLSGDRKHGDAPSPLSGDHQ 545



 Score = 92.4 bits (228), Expect = 6e-18
 Identities = 100/458 (21%), Positives = 125/458 (27%), Gaps = 10/458 (2%)

Query: 1827 GQSPSR----GRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 1882
            G +PSR     +HG          +HG          +HG       G   H  +  + S
Sbjct: 92   GDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLS 151

Query: 1883 GYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 1942
            G   HG      S    HG      S    HG +    S   +HG    +  G   HG  
Sbjct: 152  GDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGD- 210

Query: 1943 SGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQS-- 2000
               +PS   G    G   S   G    G   S   G    G   S   G R      S  
Sbjct: 211  ---APSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRL 267

Query: 2001 SGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS 2060
            SG   HG +         HG A  +      HG +  + S    HG   S+  G    G 
Sbjct: 268  SGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGE 327

Query: 2061 GSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSY 2120
               +  G    G    +      HG    R      HG      SG   H  +  + S  
Sbjct: 328  APSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGD 387

Query: 2121 SQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSG 2180
              HG      SG   HG           HG +    S    HG      SG    G    
Sbjct: 388  RTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPS 447

Query: 2181 HSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQH 2240
                   HG      S    HG    R S    +       S   +H       S    H
Sbjct: 448  PLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTH 507

Query: 2241 GSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQ 2278
            G           HG    + S   + G +    S   Q
Sbjct: 508  GDAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPLSGDHQ 545



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 97/448 (21%), Positives = 125/448 (27%), Gaps = 8/448 (1%)

Query: 2297 GQSPSR----GRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 2352
            G +PSR     +HG          +HG          +HG       G   H  +  + S
Sbjct: 92   GDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLS 151

Query: 2353 GYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 2412
            G   HG      S    HG      S    HG +    S   +HG    +  G   HG  
Sbjct: 152  GDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDA 211

Query: 2413 SGQ-SPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSS 2471
              + S     G   S  G   ++    S      + G   S  G     G   SR     
Sbjct: 212  PSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDR 271

Query: 2472 GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG 2531
             +G   S  G   THG   S  G   +   HG +  + S    HG   S+  G    G  
Sbjct: 272  THGDAPSRLGGDRTHGDAPSRLGGDRT---HGDAPSRLSGDRTHGDAPSRLGGDRTHGEA 328

Query: 2532 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS 2591
              +  G    G    +      HG    R      HG      SG   H  +  + S   
Sbjct: 329  PSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDR 388

Query: 2592 QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQ 2651
             HG      SG   HG           HG +    S    HG      SG    G     
Sbjct: 389  THGDAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSP 448

Query: 2652 SPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHG 2711
                  HG      S    HG    R S    +   L   S   +H       S    HG
Sbjct: 449  LGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHG 508

Query: 2712 SGSGHFCSQGQHGSTSGQSSTFDQEGSS 2739
                       HG    + S   + G +
Sbjct: 509  DAPSPLSGDRTHGDPLSRLSGDRKHGDA 536



 Score = 90.9 bits (224), Expect = 2e-17
 Identities = 103/463 (22%), Positives = 132/463 (28%), Gaps = 18/463 (3%)

Query: 2304 RHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGH 2363
            +HG          +HG          +HG    +  G   H  +     G   HG     
Sbjct: 90   KHGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSR 149

Query: 2364 SSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG- 2422
             S    HG      S    HG +    S    HG    +  G  +HG     +PS   G 
Sbjct: 150  LSGDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGD----APSRLGGD 205

Query: 2423 -RHGSGSGQSSSYSPYG---SGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGS 2478
              HG    + S    +G   S  G   + G   S        G   SR G    +G+  S
Sbjct: 206  RTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPS 265

Query: 2479 SSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGH 2538
                  THG   S  G   +   HG +  +      HG   S+ SG    G    +  G 
Sbjct: 266  RLSGDRTHGDAPSRLGGDRT---HGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGD 322

Query: 2539 GQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSG 2598
               G    +      HG    R      HG       G   H  +  + S    HG    
Sbjct: 323  RTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPS 382

Query: 2599 HSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRH 2658
              SG   HG    + S    HG +         HG    + SG    G           H
Sbjct: 383  RLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTH 442

Query: 2659 G---SGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSG 2715
            G   S LG   +HG   S      + G   SRL      G   S     S   +HG    
Sbjct: 443  GDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLS---RLSRDRKHGDAPS 499

Query: 2716 HFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSG 2758
                   HG      S     G    + S     G   S  SG
Sbjct: 500  PLSGDCTHGDAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPLSG 542



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 100/471 (21%), Positives = 131/471 (27%), Gaps = 19/471 (4%)

Query: 1340 GSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSS 1399
            G   S+  G  +HG    +     +HG          +HG           HG    + S
Sbjct: 92   GDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLS 151

Query: 1400 GFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSG 1459
            G   H  +    SG   HG      S    HG    + S   +HG +         HG  
Sbjct: 152  GDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDA 211

Query: 1460 SRQSLGHGQHGSGSGQSPSPSRG--RHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHS 1517
              +  G  +HG     +PS   G   HG    + S    +G          P   G   +
Sbjct: 212  PSRLSGDRKHGD----APSRLGGDRTHGDAPSRLSGDRTHGDA--------PSRLGGDRT 259

Query: 1518 SGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGS 1577
             G     SR      +G   S  G   THG   S  G   +   HG +  + S    HG 
Sbjct: 260  HG--EAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRT---HGDAPSRLSGDRTHGD 314

Query: 1578 GSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGF 1637
              S+  G    G    +  G    G    +      HG    R      HG      SG 
Sbjct: 315  APSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGD 374

Query: 1638 GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSR 1697
              H  +  + S    HG      SG   HG           HG +    S    HG    
Sbjct: 375  RTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPS 434

Query: 1698 QSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQH 1757
              SG    G           HG      S    HG    R S    +       S   +H
Sbjct: 435  HLSGDRTHGDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKH 494

Query: 1758 ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQ 1808
                   S    HG           HG    + S   + G +    S   Q
Sbjct: 495  GDAPSPLSGDCTHGDAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPLSGDHQ 545



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 83/369 (22%), Positives = 109/369 (29%), Gaps = 24/369 (6%)

Query: 2472 GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG 2531
            G  +HG +    S    H           +H  +  +     +HG   S+  G  + G  
Sbjct: 48   GDRKHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDA 107

Query: 2532 ---------SGQSPGH--GQRGSGSRQSPSYG--RHGSGSGRSSSSGQHGSGLGESSGFG 2578
                      G +P    G R  G   SP  G   HG    R S    HG      SG  
Sbjct: 108  PSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDR 167

Query: 2579 HHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQ 2638
             H  +    S    HG      SG  +HG    +      HG +    S   +HG    +
Sbjct: 168  THGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSR 227

Query: 2639 SSGHGRQGSGSGQSPSRGRHG---SGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFG 2695
              G    G    +      HG   S LG   +HG+  S      + G   SRLG     G
Sbjct: 228  LGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHG 287

Query: 2696 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQ 2755
               S  G       HG           HG    +       G +  + S     G   S+
Sbjct: 288  DAPSRLGGDRT---HGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSR 344

Query: 2756 SSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKG 2815
              G   HG    +      HG    + S    HG    + SG   HG     D  S   G
Sbjct: 345  LGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHG-----DAPSRLSG 399

Query: 2816 GSNHDGGSS 2824
               H    S
Sbjct: 400  DRTHGDAPS 408


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score =  109 bits (273), Expect = 3e-23
 Identities = 231/1034 (22%), Positives = 351/1034 (33%), Gaps = 115/1034 (11%)

Query: 307  PSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTS-----GFGQHESGSGQSSGY 361
            PS ++         + G+  + ++ +  RG  ++ +GQ S     G  Q      Q    
Sbjct: 21   PSELKKAEQQQREEAGGE--AAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAE 78

Query: 362  SKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSY----GQHESASRHSSGRGQHS 417
            S  G G G + S G  G+     +S+G  G     +++     G     S    G   HS
Sbjct: 79   SNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHS 138

Query: 418  SGSGQSPGHGQRGSGSGQSPSS--------------GQHGTGFGRSSSSG-----PYVSG 458
            + +   P     G   G+SPS+              GQ   G     S G     PY   
Sbjct: 139  AAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGP 198

Query: 459  --SGYSSGFGHHESSSEHS--SGYTQHGSGSGHSSGHGQHGSRSGQSSRGER-----QGS 509
              + +  GF +H+ +S +   S Y         SS  G        ++ G +       S
Sbjct: 199  QQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSAS 258

Query: 510  SAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSS 569
            ++ SSSS+ Q   G+    G S  G G+ Q P+ +   ++  +  SS+ G  GY  G  S
Sbjct: 259  ASSSSSSFAQQRFGAMGGGGPSAAGGGTPQ-PTATPTLNQLLTSPSSARGYQGYPGGDYS 317

Query: 570  SRGPYESGSGHSSGLGHQESRS-GQSSGYGQHGSSSGHSSTHGQHGSTS-GQSSSCGQHG 627
              GP + G+G   G     S+  G ++      ++SG +     H   S G S   GQ  
Sbjct: 318  G-GPQDGGAG--KGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPL 374

Query: 628  ATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSS 687
            A + Q SS      G  +   YG      G +P   + G   G    +G  G   G  + 
Sbjct: 375  ARTPQPSSPMDQ-MGKMRPQPYG------GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP 427

Query: 688  NGPHGSVSGQS-SGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRS----EQH 742
                 ++ G++ S  G  S + Q   Y Q G      SGY + G     + +S    +Q 
Sbjct: 428  QRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGP-----SGYGQQGQTPYYNQQSPHPQQQQ 482

Query: 743  GSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSS 802
               S    S   H   S+Q     +        P   +  S   H  S   + S  S + 
Sbjct: 483  PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTT- 541

Query: 803  SCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHG--STSGQSSSSGQHDSS 860
                            Q    S   YSQ  + S +   Q +    ST  Q ++  Q  S 
Sbjct: 542  ----------------QQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQ 585

Query: 861  SGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSG------SGQS-PSYGRHGSGS 913
              Q ++Y Q          +   GS +  +P       G      S QS PS     SGS
Sbjct: 586  QSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGS 645

Query: 914  GRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQH 973
                  G  G+ S   S  G  SS G+ S   Q        S +  H S      R    
Sbjct: 646  IDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQ--------SPFSPHTSPHLPGIRGPSP 697

Query: 974  GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGW 1033
             S  GS +S  Q  SG            G+   P P  G+  S    S +        G+
Sbjct: 698  -SPVGSPASVAQSRSGPLSPAAV----PGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGY 752

Query: 1034 S--SSRGPYESGSGHSSGLGHRESRSGQ---SSGYGQHGSSSGHSSTHGQHGSTSGQSSS 1088
               + + P  S     S L  R+   GQ     G  Q  S   +    GQ+G   G    
Sbjct: 753  MQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQ 812

Query: 1089 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 1148
               +   +    S G   +G     G G Q  G    P +G    G     S G    G 
Sbjct: 813  PNYNALPNANYPSAGM--AGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGP 870

Query: 1149 GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1208
              ++   Q GSG+    G  + ++     + +    S      GY  + ++ G    G  
Sbjct: 871  NMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGY-PNMNQGGMMGTGPP 929

Query: 1209 HGSSSGSSSHYGQ-HGSGSRQSSGHGRQGSGSGHSPSRGRHGSG---LGHSSSHGQHGSG 1264
            +G   G +S  G  +  G   S G     + +G + S    G G   L  ++       G
Sbjct: 930  YG--QGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADG 987

Query: 1265 SGRSSSRGPYESRS 1278
            + ++ S+    S S
Sbjct: 988  TPKTESKSKKSSSS 1001



 Score =  102 bits (254), Expect = 5e-21
 Identities = 222/1007 (22%), Positives = 318/1007 (31%), Gaps = 114/1007 (11%)

Query: 206  GQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSG 265
            G+  + +GQ S     G              S+G   G    G+GSG   G  +   ++ 
Sbjct: 48   GEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGG---GGAGSGGGPG-AEPDLKNS 103

Query: 266  QSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQH 325
              + G R   ++  +   G  G GS   +G     + +   P     G   G S S    
Sbjct: 104  NGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAA 163

Query: 326  GSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQAS 385
             + + +     H + G  Q+ G    +SG G                  G     +G   
Sbjct: 164  AAAAVF-----HQQHGGQQSPGLAALQSGGG------------------GGLEPYAGPQQ 200

Query: 386  SSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHG-QRGSGSGQSPSSGQHGT 444
            +S  HG  + Q +SY  + SA    +     SS  G +PG G    +GS   PSS    +
Sbjct: 201  NSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASAS 260

Query: 445  G---------FGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHG 495
                      FG     GP  +G G          + + ++  T +   +  SS  G  G
Sbjct: 261  SSSSSFAQQRFGAMGGGGPSAAGGG----------TPQPTATPTLNQLLTSPSSARGYQG 310

Query: 496  SRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQS 555
               G  S G + G +    +       G+  +   +   SG  Q     R  H   S  S
Sbjct: 311  YPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQ----QRSHHAPMSPGS 366

Query: 556  SSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGS 615
            S       G G+  +R P  S      G    +   G +    Q G  SG    HG  G 
Sbjct: 367  SG------GGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ 420

Query: 616  TSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQG-SGSGQSPSRGRHGSDFGHSSS 674
              G  +         G++ S     S + Q   YGQQG SG GQ      +     H   
Sbjct: 421  PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQ 480

Query: 675  YGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSS-GYSQHGSGSSHSSGYRKHGSRS 733
              Q    S    S  PH   S Q            S   YSQ  S   H      + S  
Sbjct: 481  --QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPS-- 536

Query: 734  GQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQ 793
             Q S ++QH  S      Y Q  + S       +Q       P+       + +     Q
Sbjct: 537  -QQSTTQQHPQS---QPPYSQPQAQSPYQQQQPQQ-------PAPSTLSQQAAYPQPQSQ 585

Query: 794  HGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSS 853
                T+ S           Q S   Q  S      S+ G    + S Q R  S    S S
Sbjct: 586  QSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGS 645

Query: 854  SGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGS 913
                D   G   +     S S  +S +G   S   QSP           SP    H  G 
Sbjct: 646  I--DDLPMGTEGALSPGVSTSGISSSQGEQ-SNPAQSP----------FSPHTSPHLPGI 692

Query: 914  GRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQH 973
               S S      S   S  G  S +            SG S S   H S + QSS ++  
Sbjct: 693  RGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSI-MHPSMN-QSSIAQDR 750

Query: 974  GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGW 1033
            G        Y Q      Q        + S + PS  +   G GS Q +S G Y    G 
Sbjct: 751  G--------YMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQ 802

Query: 1034 SSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG------STSGQSS 1087
               +G Y     +++        +G + G    G+       HGQ G         G+ S
Sbjct: 803  YGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAG---GQMHGQPGIPPYGTLPPGRMS 859

Query: 1088 --SCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHG 1145
              S G        ++   Q GSG     G   + +       H    S   + P Y    
Sbjct: 860  HASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMN 919

Query: 1146 SGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 1192
             G G   +   +G G+   +G       + Q   YS  G+ + +S+G
Sbjct: 920  QG-GMMGTGPPYGQGINSMAGM-----INPQGPPYSMGGTMANNSAG 960



 Score =  100 bits (250), Expect = 2e-20
 Identities = 231/1059 (21%), Positives = 352/1059 (33%), Gaps = 115/1059 (10%)

Query: 715  QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQH-GSGSHQSSGHGRQGSGSG 773
            +   G + ++   + G     + + E  G + G     G+    G+  + G G  G+GSG
Sbjct: 33   EEAGGEAAAAAAAERGEMKAAAGQ-ESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSG 91

Query: 774  HSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGS 833
              P     G+     +S+G  G   + +++      G G  S         G G   H  
Sbjct: 92   GGP-----GAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSS-------DGVGAPPH-- 137

Query: 834  ASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQ-SPG 892
                             S+++     + G    YG+  SA   A+    H    GQ SPG
Sbjct: 138  -----------------SAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180

Query: 893  HG--QRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSG 950
                Q G G G  P  G   +       + ++ S     S +   + +   S       G
Sbjct: 181  LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240

Query: 951  SGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPS 1010
            SG +++    GS+   SS +    S+S SSSS+ Q   G+    G    G G+ Q P+ +
Sbjct: 241  SGAAAAA---GSKPPPSSSA----SASSSSSSFAQQRFGAMGGGGPSAAGGGTPQ-PTAT 292

Query: 1011 RGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRS-GQSSGYGQHGSS 1069
               +   +  SS+ G Y+   G   S GP + G+G   G     S+  G ++      ++
Sbjct: 293  PTLNQLLTSPSSARG-YQGYPGGDYSGGPQDGGAG--KGPADMASQCWGAAAAAAAAAAA 349

Query: 1070 SGHSSTHGQHGSTS-GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG-------RQGSG 1121
            SG +     H   S G S   GQ  A + Q SS      G  +   YG       +QG  
Sbjct: 350  SGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQ-MGKMRPQPYGGTNPYSQQQGPP 408

Query: 1122 SGQSPGHGQRGS--GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSS 1179
            SG   GHG  G   GS+    Y     G  +S+  G                S + Q   
Sbjct: 409  SGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGL---------------SYTQQIPP 453

Query: 1180 YSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS 1239
            Y Q G      SGYGQ G     + +         S     Q    S+Q          S
Sbjct: 454  YGQQGP-----SGYGQQGQTPYYNQQ---------SPHPQQQQPPYSQQPPSQTPHAQPS 499

Query: 1240 GHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQ 1299
                 + +          + Q  S      S  PY S+    S   QH         YSQ
Sbjct: 500  YQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQ---STTQQHPQSQ---PPYSQ 553

Query: 1300 HGSGSGHFCSQGQHG--STSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSG 1357
              + S +   Q Q    ST  Q + + Q  S   Q ++Y  +     Q       G+ + 
Sbjct: 554  PQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQAS 613

Query: 1358 QSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQH 1417
             +PS      G    +   Q    S    S        G         S+S  SS  +Q 
Sbjct: 614  SAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISS--SQG 671

Query: 1418 GSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSP 1477
               +   S +  H S      RG    S  GS +S  Q  SG            G+   P
Sbjct: 672  EQSNPAQSPFSPHTSPHLPGIRGPSP-SPVGSPASVAQSRSGPLSPAAV----PGNQMPP 726

Query: 1478 SPSRGRHGSGSGQSSSYSPYGSGSGWS--SSRGPYESGSSHSSGLGHRESRSGQ---SSG 1532
             P  G+  S    S + S      G+   + + P  S     S L  R+   GQ     G
Sbjct: 727  RPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMG 786

Query: 1533 YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS 1592
              Q  S   +    GQ+G   G       +   +    S G   +G     G G Q  G 
Sbjct: 787  SYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGM--AGGINPMGAGGQMHGQ 844

Query: 1593 GQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ 1652
               P +G    G     S G    G   ++   Q GSG+    G  + ++     + +  
Sbjct: 845  PGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVA 904

Query: 1653 HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQS 1712
              S      GY  + ++ G    G  +G    S +    +  G   S G     + +G +
Sbjct: 905  ANSIQNRPPGY-PNMNQGGMMGTGPPYGQGINSMAGM-INPQGPPYSMGGTMANNSAGMA 962

Query: 1713 PSRGRHGSG---LGHSSSHGQHGSGSGRSSSRGPYESRS 1748
             S    G G   L  ++       G+ ++ S+    S S
Sbjct: 963  ASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSS 1001



 Score =  100 bits (248), Expect = 3e-20
 Identities = 216/927 (23%), Positives = 319/927 (34%), Gaps = 114/927 (12%)

Query: 1756 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQ 1815
            Q E   G ++A +           +G+  + +GQ S    EG + G     G+     ++
Sbjct: 31   QREEAGGEAAAAAA--------AERGEMKAAAGQES----EGPAVGPPQPLGKELQDGAE 78

Query: 1816 SSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRH--GSGSGQSSGFGH 1873
            S+     G G G + S G  G+     +S G  G     +++      G G G S G G 
Sbjct: 79   SNG----GGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGA 134

Query: 1874 HESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQS 1933
               S+  +     +G G  +               R     +++ ++  + QHG      
Sbjct: 135  PPHSAAAALPPPAYGFGQPYG--------------RSPSAVAAAAAAVFHQQHGGQQSPG 180

Query: 1934 LGHGQHGSGSGQSP--SPSRGRHGSGSGQS---------SSYGPYGSGSGWSSSRGPYES 1982
            L   Q G G G  P   P +  H  G             S+Y P       SS RG    
Sbjct: 181  LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGG-TP 239

Query: 1983 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSH 2042
            GSG ++  G +   S  +S      +SS  SS   Q   A G        G +   +++ 
Sbjct: 240  GSGAAAAAGSKPPPSSSAS------ASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATP 293

Query: 2043 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLG 2102
              +   +S SS  G QG   G   G  Q G            G+G G +  + Q     G
Sbjct: 294  TLNQLLTSPSSARGYQGYPGGDYSGGPQDG------------GAGKGPADMASQ---CWG 338

Query: 2103 ESSGFGHHESSSGQSSSYSQHGSGS-GHSSGYGQHGSRSGQSS-----RGERHGSSSGSS 2156
             ++      ++SG +   S H   S G S G GQ  +R+ Q S      G+      G +
Sbjct: 339  AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGT 398

Query: 2157 SRYG-QHGSGSRQSSGHGRQGSGSG-HSPSR------GRHGSGSGHSS------SHGQHG 2202
            + Y  Q G  S    GHG  G   G  +P R      GR  S  G  S       +GQ G
Sbjct: 399  NPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQG 458

Query: 2203 -SGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS 2261
             SG G+      Y  +S H     Q    S    + + H   S     Q Q         
Sbjct: 459  PSGYGQQGQTPYYNQQSPHPQ--QQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQP 516

Query: 2262 TFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSG 2321
             + Q+ S      S   + S  S +  + Q        P   +  + S +     Q  + 
Sbjct: 517  PYSQQPSQPPHQQSPAPYPSQQSTTQQHPQ------SQPPYSQPQAQSPYQQQQPQQPAP 570

Query: 2322 SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGE 2381
            S  S  +      S QS    + +         +Q   GS  SS+     S+ GQ    E
Sbjct: 571  STLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQ----E 626

Query: 2382 RHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS-GQSPSPSRGRHGSGSGQSSS-YSPYGS 2439
                S  S  S     SGS   L  G  G+ S G S S      G  S  + S +SP+ S
Sbjct: 627  DMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTS 686

Query: 2440 GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS---TSGQS 2496
                   RGP  S  G  + +   +SRSG  S     G+        GQ  S    S   
Sbjct: 687  -PHLPGIRGPSPSPVGSPASVA--QSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQ 743

Query: 2497 SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS 2556
            SS  Q      ++    Q+ S    S+   RQ SG     G    G GS Q  S G +G 
Sbjct: 744  SSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSG-----GQIHTGMGSYQQNSMGSYGP 798

Query: 2557 GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 2616
              G+    G +      ++    +  S+G +   +  G+G      +GQ G     +   
Sbjct: 799  QGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAG---GQMHGQPGIPPYGTLPP 855

Query: 2617 ERHGSSSGSSSHYGQHGSGSRQSSGHG 2643
             R   +S  +  YG + +      G G
Sbjct: 856  GRMSHASMGNRPYGPNMANMPPQVGSG 882



 Score = 90.1 bits (222), Expect = 3e-17
 Identities = 236/1078 (21%), Positives = 357/1078 (33%), Gaps = 147/1078 (13%)

Query: 497  RSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSS 556
            ++ Q  R E  G +A ++++  + G   + + G    G   G  P P     + G+  + 
Sbjct: 26   KAEQQQREEAGGEAAAAAAA--ERGE-MKAAAGQESEGPAVGP-PQPLGKELQDGAESNG 81

Query: 557  SYGPHGYGSGRSSSRGP-YESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGS 615
              G  G GSG      P  ++ +G++       +   +  G G  GSS G  +    H +
Sbjct: 82   GGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAP--PHSA 139

Query: 616  TSGQSSSCGQHGATSGQSSS----------HGQHGSGSSQSSRYGQQGSGSGQSPSRGRH 665
             +         G   G+S S          H QHG   S      Q G G G  P  G  
Sbjct: 140  AAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQ 199

Query: 666  GSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSG 725
             +   H     Q+ S     S+  P       SS  G   GSG ++              
Sbjct: 200  QNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAA------------- 246

Query: 726  YRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSS 785
                GS+   SS +    S+S  SSS+ Q   G+    G    G G+             
Sbjct: 247  ---AGSKPPPSSSA----SASSSSSSFAQQRFGAMGGGGPSAAGGGTPQP---------- 289

Query: 786  GHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHG 845
              +++   +   TS SS+ G+     G  SG G  + G+G+G +   S            
Sbjct: 290  --TATPTLNQLLTSPSSARGYQGYPGGDYSG-GPQDGGAGKGPADMAS------------ 334

Query: 846  STSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPS 905
               G ++++    ++SG +     H   S  +SG G         P       G  +   
Sbjct: 335  QCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQP 394

Query: 906  YGRHGSGSGRSSSSGRHGSGSGQSSGFGHKS---SSGQSSGYTQHGSGSGHSS----SYE 958
            YG      G +  S + G  SG   G G+      S     Y     G   S+    SY 
Sbjct: 395  YG------GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYT 448

Query: 959  QHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGS--RQSLGHGQHGSGSGQSPSPSRGRHGS 1016
            Q     GQ              S YGQ G      Q   H Q          PS+  H  
Sbjct: 449  QQIPPYGQQ-----------GPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQ 497

Query: 1017 GSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 1076
             S Q     P        SS+ PY   S   S   H++S +   S   Q  ++  H  + 
Sbjct: 498  PSYQQQ---PQSQPPQLQSSQPPY---SQQPSQPPHQQSPAPYPS---QQSTTQQHPQSQ 548

Query: 1077 GQHGSTSGQSSSCGQH-----GASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQR 1131
              +     QS    Q       ++  Q +++ Q  S  SQ + Y +Q     Q       
Sbjct: 549  PPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSF 608

Query: 1132 GSGSRQSPSY-GRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 1190
            GS +  +PS     G     + S     S L + SG    +   G   + S   S SG S
Sbjct: 609  GSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSG-SIDDLPMGTEGALSPGVSTSGIS 667

Query: 1191 SGYGQHG--SRSGQSSRGERH--GSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHS-PSR 1245
            S  G+    ++S  S     H  G    S S  G   S ++  SG     +  G+  P R
Sbjct: 668  SSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPR 727

Query: 1246 GRHG------------SGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 1293
               G            S +     + Q      + SS  P  + S      GQ  +G G 
Sbjct: 728  PPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMG- 786

Query: 1294 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHG 1353
              +Y Q+  GS +    GQ+G   G     +          S G  G  +   +G   HG
Sbjct: 787  --SYQQNSMGS-YGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHG 843

Query: 1354 AGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 1413
                  P  G    G    +S G    G   ++   + GSG     G  + +        
Sbjct: 844  QPG--IPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRK-------- 893

Query: 1414 CTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1473
             TQ  + + H ++        G  +  +  G   G+   YGQ G  S         G  +
Sbjct: 894  -TQETAVAMHVAANSIQNRPPGYPNMNQ--GGMMGTGPPYGQ-GINS-------MAGMIN 942

Query: 1474 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSS 1531
             Q P  S G   + +    + SP   G G      P    ++ + G    ES+S +SS
Sbjct: 943  PQGPPYSMGGTMANNSAGMAASPEMMGLG-DVKLTPATKMNNKADGTPKTESKSKKSS 999



 Score = 85.9 bits (211), Expect = 5e-16
 Identities = 204/933 (21%), Positives = 307/933 (32%), Gaps = 126/933 (13%)

Query: 946  QHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYG---QHGSGSRQSLGHGQHGSG 1002
            +   G   +++  + G     + + E  G + G     G   Q G+ S    G G  GSG
Sbjct: 33   EEAGGEAAAAAAAERGEMKAAAGQ-ESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSG 91

Query: 1003 SGQSPSP----SRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSG 1058
             G    P    S G  G     +++      G G  SS G       HS+         G
Sbjct: 92   GGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGV--GAPPHSAAAALPPPAYG 149

Query: 1059 QSSGYGQHGSSSGHSST---HGQHGSTSGQSSSCGQHGASSG-------QSSSHGQHGSG 1108
                YG+  S+   ++    H QHG       +  Q G   G       Q +SH      
Sbjct: 150  FGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPN 209

Query: 1109 SSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFG 1168
               +S Y  + +    +P +      +  SP  G  GSG+  ++ S    S         
Sbjct: 210  HQYNSYYPNRSAYPPPAPAY------ALSSPRGGTPGSGAAAAAGSKPPPSSSA------ 257

Query: 1169 HHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQ-SSRGERHGSSSGSSSHYGQHGSGSR 1227
               S+S  SSS++Q   G+    G    G  + Q ++    +   +  SS  G  G    
Sbjct: 258  ---SASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGG 314

Query: 1228 QSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQH 1287
              SG G Q  G+G  P+          S   G   + +  +++ G  + RS H+ +    
Sbjct: 315  DYSG-GPQDGGAGKGPADMA-------SQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGS 366

Query: 1288 ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGS--GSSQ 1345
              G G   A +   S       + +     G +    Q+G  +G    +G+ G   GS  
Sbjct: 367  SGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQT 426

Query: 1346 SSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHE 1405
               Y     G  QS   G   S +     YGQ G             SG GQ     ++ 
Sbjct: 427  PQRYPMTMQGRAQSAMGGL--SYTQQIPPYGQQGP------------SGYGQQGQTPYYN 472

Query: 1406 SSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLG 1465
              S       Q    S    S   H   S Q     +      S   Y Q  S       
Sbjct: 473  QQSPHPQ--QQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQ-- 528

Query: 1466 HGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRES 1525
                     QSP+P   +  +      S  PY        ++ PY+             S
Sbjct: 529  ---------QSPAPYPSQQSTTQQHPQSQPPYSQ----PQAQSPYQQQQPQQPA----PS 571

Query: 1526 RSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHG--ASSGQSSSHGQHGSGSSQSS 1583
               Q + Y Q  S     + + Q      Q  S    G  ASS  S +  + G      S
Sbjct: 572  TLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLS 631

Query: 1584 GYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESS 1643
               R  S    S        G+  + S G   S SG SSS G+  +     S F  H S 
Sbjct: 632  LQSRPSSLPDLSGSIDDLPMGTEGALSPGV--STSGISSSQGEQSNPA--QSPFSPHTSP 687

Query: 1644 S------------GQSSSYSQHGSGSGHSSGYGQHGSR------SGQSSRGERHGSSSRS 1685
                         G  +S +Q  S SG  S     G++      SGQS     H S ++S
Sbjct: 688  HLPGIRGPSPSPVGSPASVAQ--SRSGPLSPAAVPGNQMPPRPPSGQSD-SIMHPSMNQS 744

Query: 1686 SSR----YGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLG--HSSSHGQHGSGSGRSS 1739
            S      Y Q      Q S      + S + PS G+  +G+G    +S G +G   G+  
Sbjct: 745  SIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYG 804

Query: 1740 SRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSS 1799
             +G Y  +  ++++   +   +G +   +  G+G          G   GQ          
Sbjct: 805  PQGGYPRQPNYNALPNANYPSAGMAGGINPMGAG----------GQMHGQPGIPPYGTLP 854

Query: 1800 TGQSS--SHGQHGSGSSQSSSYGQQGSGSGQSP 1830
             G+ S  S G    G + ++   Q GSG    P
Sbjct: 855  PGRMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887



 Score = 84.3 bits (207), Expect = 2e-15
 Identities = 197/808 (24%), Positives = 267/808 (33%), Gaps = 115/808 (14%)

Query: 2092 SSSGQH--GPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS-RSGQSSRGER 2148
            +++GQ   GP +G     G  E   G  S+    G G+G   G G     ++   + G R
Sbjct: 52   AAAGQESEGPAVGPPQPLGK-ELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPR 110

Query: 2149 HGSSSGSSSRYGQHGSGSRQSSG---HGRQ----------GSGSGHSPSRGRHGSGSGHS 2195
               ++  +   G  G GS    G   H             G   G SPS     + +   
Sbjct: 111  PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFH 170

Query: 2196 SSHG----------QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSG 2245
              HG          Q G G G     GP ++   H     Q+ S   + SAY        
Sbjct: 171  QQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPA-- 228

Query: 2246 HFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQ--GSGSGQSPSRG 2303
             +      G T G S      GS    SSS     S SS SSS+ QQ  G+  G  PS  
Sbjct: 229  -YALSSPRGGTPG-SGAAAAAGSKPPPSSS----ASASSSSSSFAQQRFGAMGGGGPSAA 282

Query: 2304 RHGSGSGHSSS-----YGQHGSGSGWSSSSGRHGSGSGQSSGFGHHE----SSSW-QSSG 2353
              G+    ++           S  G+    G   SG  Q  G G       S  W  ++ 
Sbjct: 283  GGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAA 342

Query: 2354 YTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 2413
                 + SG +     H   S  SS G     +     S      G  +   +G     S
Sbjct: 343  AAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYS 402

Query: 2414 GQSPSPSRGRHGSG-SGQSSSYSPYGSGSGWS---SSRGPYESGSGHSSGLGHRESRS-- 2467
             Q   PS  + G G  GQ     PYGS +      + +G  +S  G   GL + +     
Sbjct: 403  QQQGPPSGPQQGHGYPGQ-----PYGSQTPQRYPMTMQGRAQSAMG---GLSYTQQIPPY 454

Query: 2468 GQS--SGYGQHGSSSGHS--STHGQHGST--SGQSSSCGQHGASSGQSSSHGQHGSGSSQ 2521
            GQ   SGYGQ G +  ++  S H Q      S Q  S   H   S Q     Q     S 
Sbjct: 455  GQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSS 514

Query: 2522 SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHE 2581
               Y +Q S     P H Q  +      S  +    S    S  Q  S   +        
Sbjct: 515  QPPYSQQPS----QPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAP 570

Query: 2582 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGS-----SSHYGQHGSG- 2635
            S+  Q ++Y Q  S     + Y Q      Q    +  GS + S     SS  GQ     
Sbjct: 571  STLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNL 630

Query: 2636 ---SRQSSGHGRQGS------GSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSS------ 2680
               SR SS     GS      G+  + S G   SG+  SSS G+  + +    S      
Sbjct: 631  SLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGI--SSSQGEQSNPAQSPFSPHTSPH 688

Query: 2681 ----RGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF--- 2733
                RGP  S +G  +   Q  SG    +A   +         Q      SGQS +    
Sbjct: 689  LPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGN---------QMPPRPPSGQSDSIMHP 739

Query: 2734 DQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQ-----SSSYGQH 2788
                SS  Q   Y  R     Q S      A S +  S G+  +G G        SYG  
Sbjct: 740  SMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQ 799

Query: 2789 GSGSGQSSGYSQHGSGSGQDGYSYCKGG 2816
            G   G   GY +  + +     +Y   G
Sbjct: 800  GGQYGPQGGYPRQPNYNALPNANYPSAG 827



 Score = 79.3 bits (194), Expect = 5e-14
 Identities = 204/937 (21%), Positives = 286/937 (30%), Gaps = 173/937 (18%)

Query: 1434 SGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP----SRGRHGSGSG 1489
            +GQ S G   G          Q G+ S    G G  GSG G    P    S G  G    
Sbjct: 54   AGQESEGPAVGPPQPLGKEL-QDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPA 112

Query: 1490 QSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSST---H 1546
             +++ +    G G  SS G       HS+         G    YG+  S+   ++    H
Sbjct: 113  LNNNLTEPPGGGGGGSSDGV--GAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFH 170

Query: 1547 GQHGSTSGQSSSCGQHGASSG-------QSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHG 1599
             QHG       +  Q G   G       Q +SH  HG  + Q + Y            + 
Sbjct: 171  QQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSH-DHGFPNHQYNSY------------YP 217

Query: 1600 QRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH 1659
             R +    +P+Y         S   G  GSG   ++G     SSS  +SS          
Sbjct: 218  NRSAYPPPAPAYALS------SPRGGTPGSGAAAAAGSKPPPSSSASASS---------- 261

Query: 1660 SSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQ-------- 1711
                                     SSS + Q   G+    G    G G+ Q        
Sbjct: 262  -------------------------SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLN 296

Query: 1712 ----SPSRGRHGSGL-GHSSSHGQHGSGSGR-------------------SSSRGPYESR 1747
                SPS  R   G  G   S G    G+G+                   +++ G  + R
Sbjct: 297  QLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQR 356

Query: 1748 SGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHG 1807
            S H+ +      G G   A +   S       + +     G +    Q+G  +G    HG
Sbjct: 357  SHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHG 416

Query: 1808 QHGS--GSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 1865
              G   GS     Y     G  QS   G   S +     YGQ G             SG 
Sbjct: 417  YPGQPYGSQTPQRYPMTMQGRAQSAMGGL--SYTQQIPPYGQQGP------------SGY 462

Query: 1866 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQ 1925
            GQ     ++   S       Q    S    S   H   S Q     Q      S   Y Q
Sbjct: 463  GQQGQTPYYNQQS--PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQ 520

Query: 1926 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWS-----SSRGPY 1980
              S                QSP+P   +  +      S  PY      S       + P 
Sbjct: 521  QPSQPPHQ-----------QSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPA 569

Query: 1981 ESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS-ASGQSSSCGQHGASSGQS 2039
             S     +     +S+  Q + Y Q         +    GS AS   S     G     +
Sbjct: 570  PSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMN 629

Query: 2040 SSHGQHGSGSSQSSGY---GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQ 2096
             S     S     SG       G+    SPG    G  S Q      + + S  S  +  
Sbjct: 630  LSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQ--SNPAQSPFSPHTSP 687

Query: 2097 HGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR------SGQSS---RGE 2147
            H PG+      G   S  G  +S +Q  S SG  S     G++      SGQS       
Sbjct: 688  HLPGIR-----GPSPSPVGSPASVAQ--SRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS 740

Query: 2148 RHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGR--HGSGSGHSSSHGQHGSGS 2205
             + SS      Y Q      Q S      + S   PS G+   G GS   +S G +G   
Sbjct: 741  MNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG 800

Query: 2206 GRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 2265
            G+   +G Y  +  ++++   +   +G +   +  G+G          G   GQ      
Sbjct: 801  GQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAG----------GQMHGQPGIPPY 850

Query: 2266 EGSSTGQSS--SHGQHGSGSSQSSSYGQQGSGSGQSP 2300
                 G+ S  S G    G + ++   Q GSG    P
Sbjct: 851  GTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887



 Score = 72.8 bits (177), Expect = 5e-12
 Identities = 144/618 (23%), Positives = 216/618 (34%), Gaps = 97/618 (15%)

Query: 2226 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQ 2285
            Q E   G ++A +           +G+  + +GQ S    EG + G     G+     ++
Sbjct: 31   QREEAGGEAAAAAA--------AERGEMKAAAGQES----EGPAVGPPQPLGKELQDGAE 78

Query: 2286 SSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRH--GSGSGQSSGFGH 2343
            S+     G G G + S G  G+     +S G  G     +++      G G G S G G 
Sbjct: 79   SNG----GGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGA 134

Query: 2344 HESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQS 2403
               S+  +     +G G  +               R     +++ ++  + QHG      
Sbjct: 135  PPHSAAAALPPPAYGFGQPYG--------------RSPSAVAAAAAAVFHQQHGGQQSPG 180

Query: 2404 LGHGQHGSGSGQSP--SPSRGRHGSGSGQS---------SSYSPYGSGSGWSSSRGPYES 2452
            L   Q G G G  P   P +  H  G             S+Y P       SS RG    
Sbjct: 181  LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGG-TP 239

Query: 2453 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH 2512
            GSG ++  G +   S  +S      SSS  S    + G+  G   S    G +   +++ 
Sbjct: 240  GSGAAAAAGSKPPPSSSASA-----SSSSSSFAQQRFGAMGGGGPSAAG-GGTPQPTATP 293

Query: 2513 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLG 2572
              +   +S SS  G QG   G   G  Q G            G+G G +  + Q     G
Sbjct: 294  TLNQLLTSPSSARGYQGYPGGDYSGGPQDG------------GAGKGPADMASQ---CWG 338

Query: 2573 ESSGFGHHESSSGQSSSYSQHGSGS-GHSSGYGQHGSRSGQSS-----RGERHGSSSGSS 2626
             ++      ++SG +   S H   S G S G GQ  +R+ Q S      G+      G +
Sbjct: 339  AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGT 398

Query: 2627 SHYG-QHGSGSRQSSGHGRQGSGSG-QSPSR------GRHGSGLGHSS------SHGQHG 2672
            + Y  Q G  S    GHG  G   G Q+P R      GR  S +G  S       +GQ G
Sbjct: 399  NPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQG 458

Query: 2673 -SGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS 2731
             SG G+      Y  +  H     Q    S    + + H   S     Q Q         
Sbjct: 459  PSGYGQQGQTPYYNQQSPHPQ--QQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQP 516

Query: 2732 TFDQEGSSTGQSSS---YGHRGSGSSQ----SSGYGRHGAGSGQSLSHGRHGSGS--GQS 2782
             + Q+ S      S   Y  + S + Q       Y +  A S       +  + S   Q 
Sbjct: 517  PYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQ 576

Query: 2783 SSYGQHGSGSGQSSGYSQ 2800
            ++Y Q  S   Q + YSQ
Sbjct: 577  AAYPQPQSQQSQQTAYSQ 594



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 152/705 (21%), Positives = 223/705 (31%), Gaps = 79/705 (11%)

Query: 176 SSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHK 235
           S  +G   + +  ++  G     S  +P       G GQ  +     S      G  + +
Sbjct: 334 SQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQ 393

Query: 236 SSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLG 295
              G +    Q G  SG   G+G  G   G  +      +  G + S     S ++Q   
Sbjct: 394 PYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPP 453

Query: 296 HGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGS 355
           +G+QG                   S +GQ G    Y+    H +          Q    S
Sbjct: 454 YGQQG------------------PSGYGQQGQTPYYNQQSPHPQQ---------QQPPYS 486

Query: 356 GQSSGYSKHGSGSGHSSSQGQHGS-TSGQASSSGQHGSSSRQSSSY---GQHESASRHSS 411
            Q    + H   S     Q Q     S Q   S Q      Q S      Q  +  +H  
Sbjct: 487 QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQ 546

Query: 412 GRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYS-SGFGHHES 470
            +  +S    QSP   Q+      S  S Q      +S  S      + YS   F   + 
Sbjct: 547 SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQS----QQTAYSQQRFPPPQE 602

Query: 471 SSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGH 530
            S+ S G     + S  SS  GQ        SR       +GS       G+    S G 
Sbjct: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPM-GTEGALSPGV 661

Query: 531 SRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESR 590
           S  G  S Q         E  +   S + PH         RGP  S  G  + +   +SR
Sbjct: 662 STSGISSSQG--------EQSNPAQSPFSPH-TSPHLPGIRGPSPSPVGSPASVA--QSR 710

Query: 591 SGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYG 650
           SG  S     G+              SGQS S           +    +   + Q  +Y 
Sbjct: 711 SGPLSPAAVPGNQM-------PPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYS 763

Query: 651 QQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQS 710
               GS  SP +   G       SY Q+  G     S GP G   GQ   +G + G  + 
Sbjct: 764 SPQPGSALSPRQPSGGQIHTGMGSYQQNSMG-----SYGPQG---GQ---YGPQGGYPRQ 812

Query: 711 SGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGS 770
             Y+   + +  S+G    G  +   +  + HG            G  SH S G+   G 
Sbjct: 813 PNYNALPNANYPSAGMA--GGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGP 870

Query: 771 GSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHE------SGS 824
              + P +V     SG     G     T  ++   H  + S Q    G          G+
Sbjct: 871 NMANMPPQV----GSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGT 926

Query: 825 GQGYSQH-GSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYG 868
           G  Y Q   S +G  + QG   S  G  +++    ++S +    G
Sbjct: 927 GPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLG 971



 Score = 35.8 bits (81), Expect = 0.62
 Identities = 92/435 (21%), Positives = 147/435 (33%), Gaps = 36/435 (8%)

Query: 1589 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSS 1648
            GSGS Q P   Q  S S       +  + +    S      G+  S+  G  ++ +  S 
Sbjct: 1137 GSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSD 1196

Query: 1649 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSG 1708
            S  Q  +    + GY    + S    R     +     S     GS    SSG G  G G
Sbjct: 1197 STFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNG-G 1255

Query: 1709 SGQSPSRGRHGSGLGHSS----SHGQHGSGSGRSSSR---GPYESRSGHSS----VFGQH 1757
             G   SR   G GLG+ +     H  +G    R  +    GP  + S  +     +    
Sbjct: 1256 MGDPYSRAA-GPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNP 1314

Query: 1758 ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSS 1817
            +SG    S Y            Q +H S   Q ST   +G+ +G      Q      Q  
Sbjct: 1315 DSGMYSPSRYPPQQQQQ----QQQRHDSYGNQFST---QGTPSGSPFPSQQTTMYQQQQQ 1367

Query: 1818 SYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESS 1877
            +Y +   G+   P++   G       S GQ G          +    S Q +        
Sbjct: 1368 NYKRPMDGTYGPPAKRHEGEMYSVPYSTGQ-GQPQQQQLPPAQPQPASQQQAA-----QP 1421

Query: 1878 SWQSSGYTQHGSG--SGHSSSYEQHGSRSGQSSRGEQHGSS--SGSSSSYGQHGSGSRQS 1933
            S Q   Y Q+G+   +  +++ E+  +   Q+    Q G    S    +  Q     +  
Sbjct: 1422 SPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMM 1481

Query: 1934 LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHR 1993
             G  Q  +   Q  +  +GR+        +Y      S  S+ +GP   G   +  + H 
Sbjct: 1482 GGPIQASAEVAQQGTMWQGRN------DMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHT 1535

Query: 1994 ESRSGQSSGYGQHGS 2008
            + R+     +  HG+
Sbjct: 1536 DQRANHEGSWPSHGT 1550



 Score = 35.0 bits (79), Expect = 1.1
 Identities = 91/435 (20%), Positives = 148/435 (34%), Gaps = 36/435 (8%)

Query: 2059 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSS 2118
            GSGS Q P   Q  S S       +  + +    S     PG+  S+  G  ++ +  S 
Sbjct: 1137 GSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSD 1196

Query: 2119 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSG 2178
            S  Q  +    + GY    + S    R     +     S     GS    SSG G  G G
Sbjct: 1197 STFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNG-G 1255

Query: 2179 SGHSPSRGRHGSGSGHSS----SHGQHGSGSGRSSSR---GPYESRSGHSS----VFGQH 2227
             G   SR   G G G+ +     H  +G    R  +    GP  + S  +     +    
Sbjct: 1256 MGDPYSRAA-GPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNP 1314

Query: 2228 ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSS 2287
            +SG    S Y            Q +H S   Q ST   +G+ +G      Q      Q  
Sbjct: 1315 DSGMYSPSRYPPQQQQQ----QQQRHDSYGNQFST---QGTPSGSPFPSQQTTMYQQQQQ 1367

Query: 2288 SYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESS 2347
            +Y +   G+   P++   G       S GQ G          +    S Q +        
Sbjct: 1368 NYKRPMDGTYGPPAKRHEGEMYSVPYSTGQ-GQPQQQQLPPAQPQPASQQQAA-----QP 1421

Query: 2348 SWQSSGYTQHGSG--SGHSSSYEQHGSRSGQSSRGERHGSS--SGSSSSYGQHGSGSRQS 2403
            S Q   Y Q+G+   +  +++ E+  +   Q+    + G    S    +  Q     +  
Sbjct: 1422 SPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMM 1481

Query: 2404 LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHR 2463
             G  Q  +   Q  +  +GR+        +Y+     S  S+ +GP   G   +  + H 
Sbjct: 1482 GGPIQASAEVAQQGTMWQGRN------DMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHT 1535

Query: 2464 ESRSGQSSGYGQHGS 2478
            + R+     +  HG+
Sbjct: 1536 DQRANHEGSWPSHGT 1550



 Score = 33.9 bits (76), Expect = 2.4
 Identities = 87/445 (19%), Positives = 147/445 (33%), Gaps = 60/445 (13%)

Query: 653  GSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVS-------GQSSGFGHKS 705
            GSGS Q P   +       SSS  + G     + ++ PH  +          S G     
Sbjct: 1137 GSGSMQGPQTPQ-----STSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAF 1191

Query: 706  GSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGH 765
              G  S + +  S  + + GY+   + S    R     +     S     GS    SSG 
Sbjct: 1192 NDGSDSTFQKRNS-MTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQ 1250

Query: 766  GRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSG 825
            G  G            G    +S + G  G G        HY  G      + +  +  G
Sbjct: 1251 GPNG------------GMGDPYSRAAGP-GLGNVAMGPRQHYPYGGP----YDRVRTEPG 1293

Query: 826  QGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSS----SGQSSSYGQHESASHHASGRG 881
             G        G+ S+     +    +  SG +  S      Q     +H+S  +  S +G
Sbjct: 1294 IG------PEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQG 1347

Query: 882  RHGSGS---GQSPGHGQRGSGSGQSPSYGRHGSGSGRSSS---SGRHGSGSGQSSGFGHK 935
               SGS    Q     Q+   + + P  G +G  + R      S  + +G GQ       
Sbjct: 1348 TP-SGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLP 1406

Query: 936  SSSGQSSGYTQHGSGSGHSSSYEQHGSR-----SGQSSRSEQHGSSSGSSSSYGQH---- 986
             +  Q +   Q    S     Y Q+G+      +  + R    G  +     +G+     
Sbjct: 1407 PAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSA 1466

Query: 987  --GSGSRQSLGHGQHGSGSGQSPSPSR-GRHGSGSGQSSSYGPYRSGSGWSSSRGPYESG 1043
              G+ ++Q++     G     S   ++ G    G    +     R  +G S+ +GP   G
Sbjct: 1467 PPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTG-SAPQGPAYHG 1525

Query: 1044 SGHSSGLGHRESRSGQSSGYGQHGS 1068
               +  + H + R+     +  HG+
Sbjct: 1526 VNRTDEMLHTDQRANHEGSWPSHGT 1550



 Score = 32.7 bits (73), Expect = 5.3
 Identities = 88/426 (20%), Positives = 139/426 (32%), Gaps = 44/426 (10%)

Query: 210  SGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGS--GSGHSSGYG-QHGSRSGQ 266
            +GSG      T  S S   +     K  +  S+ +SQ     G   S+  G Q     G 
Sbjct: 1136 AGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGS 1195

Query: 267  SSRGERHRSSS---GSSSSYGQHGSGSRQSLGHGRQGSGS-RQSPSHVRHGSGSGHSSSH 322
             S  ++  S +   G   S        R S    +   GS R++P     GS    SS  
Sbjct: 1196 DSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAP-----GSDPFMSSGQ 1250

Query: 323  GQHGSGSSYSYSR------GHYESGSGQTSGFG------QHESGSGQSSGYSKHGSGSGH 370
            G +G G    YSR      G+   G  Q   +G      + E G G     S        
Sbjct: 1251 GPNG-GMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNL 1309

Query: 371  SSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRG 430
              S    G  S       Q     ++  SYG   S     SG    S    Q     Q+ 
Sbjct: 1310 MPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSG----SPFPSQQTTMYQQQ 1365

Query: 431  SGSGQSPSSGQHGTGFGRSSS---SGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGH 487
              + + P  G +G    R      S PY +G G         +  + +S   Q    S  
Sbjct: 1366 QQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPAS-QQQAAQPSPQ 1424

Query: 488  SSGHGQHGSRSGQSSRGERQGSSAGSSSS-----YGQH------GSGSRQSLGHSRHGSG 536
               + Q+G+    ++    +   AG   +     +G+       G+ ++Q++     G  
Sbjct: 1425 QDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGP 1484

Query: 537  SGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSG 596
               S   ++       R   +Y      S  S+ +GP   G   +  + H + R+     
Sbjct: 1485 IQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGS 1544

Query: 597  YGQHGS 602
            +  HG+
Sbjct: 1545 WPSHGT 1550


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score =  109 bits (273), Expect = 3e-23
 Identities = 231/1034 (22%), Positives = 351/1034 (33%), Gaps = 115/1034 (11%)

Query: 307  PSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTS-----GFGQHESGSGQSSGY 361
            PS ++         + G+  + ++ +  RG  ++ +GQ S     G  Q      Q    
Sbjct: 21   PSELKKAEQQQREEAGGE--AAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAE 78

Query: 362  SKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSY----GQHESASRHSSGRGQHS 417
            S  G G G + S G  G+     +S+G  G     +++     G     S    G   HS
Sbjct: 79   SNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHS 138

Query: 418  SGSGQSPGHGQRGSGSGQSPSS--------------GQHGTGFGRSSSSG-----PYVSG 458
            + +   P     G   G+SPS+              GQ   G     S G     PY   
Sbjct: 139  AAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGP 198

Query: 459  --SGYSSGFGHHESSSEHS--SGYTQHGSGSGHSSGHGQHGSRSGQSSRGER-----QGS 509
              + +  GF +H+ +S +   S Y         SS  G        ++ G +       S
Sbjct: 199  QQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSAS 258

Query: 510  SAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSS 569
            ++ SSSS+ Q   G+    G S  G G+ Q P+ +   ++  +  SS+ G  GY  G  S
Sbjct: 259  ASSSSSSFAQQRFGAMGGGGPSAAGGGTPQ-PTATPTLNQLLTSPSSARGYQGYPGGDYS 317

Query: 570  SRGPYESGSGHSSGLGHQESRS-GQSSGYGQHGSSSGHSSTHGQHGSTS-GQSSSCGQHG 627
              GP + G+G   G     S+  G ++      ++SG +     H   S G S   GQ  
Sbjct: 318  G-GPQDGGAG--KGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPL 374

Query: 628  ATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSS 687
            A + Q SS      G  +   YG      G +P   + G   G    +G  G   G  + 
Sbjct: 375  ARTPQPSSPMDQ-MGKMRPQPYG------GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP 427

Query: 688  NGPHGSVSGQS-SGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRS----EQH 742
                 ++ G++ S  G  S + Q   Y Q G      SGY + G     + +S    +Q 
Sbjct: 428  QRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGP-----SGYGQQGQTPYYNQQSPHPQQQQ 482

Query: 743  GSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSS 802
               S    S   H   S+Q     +        P   +  S   H  S   + S  S + 
Sbjct: 483  PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTT- 541

Query: 803  SCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHG--STSGQSSSSGQHDSS 860
                            Q    S   YSQ  + S +   Q +    ST  Q ++  Q  S 
Sbjct: 542  ----------------QQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQ 585

Query: 861  SGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSG------SGQS-PSYGRHGSGS 913
              Q ++Y Q          +   GS +  +P       G      S QS PS     SGS
Sbjct: 586  QSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGS 645

Query: 914  GRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQH 973
                  G  G+ S   S  G  SS G+ S   Q        S +  H S      R    
Sbjct: 646  IDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQ--------SPFSPHTSPHLPGIRGPSP 697

Query: 974  GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGW 1033
             S  GS +S  Q  SG            G+   P P  G+  S    S +        G+
Sbjct: 698  -SPVGSPASVAQSRSGPLSPAAV----PGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGY 752

Query: 1034 S--SSRGPYESGSGHSSGLGHRESRSGQ---SSGYGQHGSSSGHSSTHGQHGSTSGQSSS 1088
               + + P  S     S L  R+   GQ     G  Q  S   +    GQ+G   G    
Sbjct: 753  MQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQ 812

Query: 1089 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 1148
               +   +    S G   +G     G G Q  G    P +G    G     S G    G 
Sbjct: 813  PNYNALPNANYPSAGM--AGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGP 870

Query: 1149 GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1208
              ++   Q GSG+    G  + ++     + +    S      GY  + ++ G    G  
Sbjct: 871  NMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGY-PNMNQGGMMGTGPP 929

Query: 1209 HGSSSGSSSHYGQ-HGSGSRQSSGHGRQGSGSGHSPSRGRHGSG---LGHSSSHGQHGSG 1264
            +G   G +S  G  +  G   S G     + +G + S    G G   L  ++       G
Sbjct: 930  YG--QGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADG 987

Query: 1265 SGRSSSRGPYESRS 1278
            + ++ S+    S S
Sbjct: 988  TPKTESKSKKSSSS 1001



 Score =  102 bits (254), Expect = 5e-21
 Identities = 222/1007 (22%), Positives = 318/1007 (31%), Gaps = 114/1007 (11%)

Query: 206  GQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSG 265
            G+  + +GQ S     G              S+G   G    G+GSG   G  +   ++ 
Sbjct: 48   GEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGG---GGAGSGGGPG-AEPDLKNS 103

Query: 266  QSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQH 325
              + G R   ++  +   G  G GS   +G     + +   P     G   G S S    
Sbjct: 104  NGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAA 163

Query: 326  GSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQAS 385
             + + +     H + G  Q+ G    +SG G                  G     +G   
Sbjct: 164  AAAAVF-----HQQHGGQQSPGLAALQSGGG------------------GGLEPYAGPQQ 200

Query: 386  SSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHG-QRGSGSGQSPSSGQHGT 444
            +S  HG  + Q +SY  + SA    +     SS  G +PG G    +GS   PSS    +
Sbjct: 201  NSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASAS 260

Query: 445  G---------FGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHG 495
                      FG     GP  +G G          + + ++  T +   +  SS  G  G
Sbjct: 261  SSSSSFAQQRFGAMGGGGPSAAGGG----------TPQPTATPTLNQLLTSPSSARGYQG 310

Query: 496  SRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQS 555
               G  S G + G +    +       G+  +   +   SG  Q     R  H   S  S
Sbjct: 311  YPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQ----QRSHHAPMSPGS 366

Query: 556  SSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGS 615
            S       G G+  +R P  S      G    +   G +    Q G  SG    HG  G 
Sbjct: 367  SG------GGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ 420

Query: 616  TSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQG-SGSGQSPSRGRHGSDFGHSSS 674
              G  +         G++ S     S + Q   YGQQG SG GQ      +     H   
Sbjct: 421  PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQ 480

Query: 675  YGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSS-GYSQHGSGSSHSSGYRKHGSRS 733
              Q    S    S  PH   S Q            S   YSQ  S   H      + S  
Sbjct: 481  --QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPS-- 536

Query: 734  GQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQ 793
             Q S ++QH  S      Y Q  + S       +Q       P+       + +     Q
Sbjct: 537  -QQSTTQQHPQS---QPPYSQPQAQSPYQQQQPQQ-------PAPSTLSQQAAYPQPQSQ 585

Query: 794  HGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSS 853
                T+ S           Q S   Q  S      S+ G    + S Q R  S    S S
Sbjct: 586  QSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGS 645

Query: 854  SGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGS 913
                D   G   +     S S  +S +G   S   QSP           SP    H  G 
Sbjct: 646  I--DDLPMGTEGALSPGVSTSGISSSQGEQ-SNPAQSP----------FSPHTSPHLPGI 692

Query: 914  GRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQH 973
               S S      S   S  G  S +            SG S S   H S + QSS ++  
Sbjct: 693  RGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSI-MHPSMN-QSSIAQDR 750

Query: 974  GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGW 1033
            G        Y Q      Q        + S + PS  +   G GS Q +S G Y    G 
Sbjct: 751  G--------YMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQ 802

Query: 1034 SSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG------STSGQSS 1087
               +G Y     +++        +G + G    G+       HGQ G         G+ S
Sbjct: 803  YGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAG---GQMHGQPGIPPYGTLPPGRMS 859

Query: 1088 --SCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHG 1145
              S G        ++   Q GSG     G   + +       H    S   + P Y    
Sbjct: 860  HASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMN 919

Query: 1146 SGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 1192
             G G   +   +G G+   +G       + Q   YS  G+ + +S+G
Sbjct: 920  QG-GMMGTGPPYGQGINSMAGM-----INPQGPPYSMGGTMANNSAG 960



 Score =  100 bits (250), Expect = 2e-20
 Identities = 231/1059 (21%), Positives = 352/1059 (33%), Gaps = 115/1059 (10%)

Query: 715  QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQH-GSGSHQSSGHGRQGSGSG 773
            +   G + ++   + G     + + E  G + G     G+    G+  + G G  G+GSG
Sbjct: 33   EEAGGEAAAAAAAERGEMKAAAGQ-ESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSG 91

Query: 774  HSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGS 833
              P     G+     +S+G  G   + +++      G G  S         G G   H  
Sbjct: 92   GGP-----GAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSS-------DGVGAPPH-- 137

Query: 834  ASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQ-SPG 892
                             S+++     + G    YG+  SA   A+    H    GQ SPG
Sbjct: 138  -----------------SAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180

Query: 893  HG--QRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSG 950
                Q G G G  P  G   +       + ++ S     S +   + +   S       G
Sbjct: 181  LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240

Query: 951  SGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPS 1010
            SG +++    GS+   SS +    S+S SSSS+ Q   G+    G    G G+ Q P+ +
Sbjct: 241  SGAAAAA---GSKPPPSSSA----SASSSSSSFAQQRFGAMGGGGPSAAGGGTPQ-PTAT 292

Query: 1011 RGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRS-GQSSGYGQHGSS 1069
               +   +  SS+ G Y+   G   S GP + G+G   G     S+  G ++      ++
Sbjct: 293  PTLNQLLTSPSSARG-YQGYPGGDYSGGPQDGGAG--KGPADMASQCWGAAAAAAAAAAA 349

Query: 1070 SGHSSTHGQHGSTS-GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG-------RQGSG 1121
            SG +     H   S G S   GQ  A + Q SS      G  +   YG       +QG  
Sbjct: 350  SGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQ-MGKMRPQPYGGTNPYSQQQGPP 408

Query: 1122 SGQSPGHGQRGS--GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSS 1179
            SG   GHG  G   GS+    Y     G  +S+  G                S + Q   
Sbjct: 409  SGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGL---------------SYTQQIPP 453

Query: 1180 YSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS 1239
            Y Q G      SGYGQ G     + +         S     Q    S+Q          S
Sbjct: 454  YGQQGP-----SGYGQQGQTPYYNQQ---------SPHPQQQQPPYSQQPPSQTPHAQPS 499

Query: 1240 GHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQ 1299
                 + +          + Q  S      S  PY S+    S   QH         YSQ
Sbjct: 500  YQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQ---STTQQHPQSQ---PPYSQ 553

Query: 1300 HGSGSGHFCSQGQHG--STSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSG 1357
              + S +   Q Q    ST  Q + + Q  S   Q ++Y  +     Q       G+ + 
Sbjct: 554  PQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQAS 613

Query: 1358 QSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQH 1417
             +PS      G    +   Q    S    S        G         S+S  SS  +Q 
Sbjct: 614  SAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISS--SQG 671

Query: 1418 GSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSP 1477
               +   S +  H S      RG    S  GS +S  Q  SG            G+   P
Sbjct: 672  EQSNPAQSPFSPHTSPHLPGIRGPSP-SPVGSPASVAQSRSGPLSPAAV----PGNQMPP 726

Query: 1478 SPSRGRHGSGSGQSSSYSPYGSGSGWS--SSRGPYESGSSHSSGLGHRESRSGQ---SSG 1532
             P  G+  S    S + S      G+   + + P  S     S L  R+   GQ     G
Sbjct: 727  RPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMG 786

Query: 1533 YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS 1592
              Q  S   +    GQ+G   G       +   +    S G   +G     G G Q  G 
Sbjct: 787  SYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGM--AGGINPMGAGGQMHGQ 844

Query: 1593 GQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ 1652
               P +G    G     S G    G   ++   Q GSG+    G  + ++     + +  
Sbjct: 845  PGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVA 904

Query: 1653 HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQS 1712
              S      GY  + ++ G    G  +G    S +    +  G   S G     + +G +
Sbjct: 905  ANSIQNRPPGY-PNMNQGGMMGTGPPYGQGINSMAGM-INPQGPPYSMGGTMANNSAGMA 962

Query: 1713 PSRGRHGSG---LGHSSSHGQHGSGSGRSSSRGPYESRS 1748
             S    G G   L  ++       G+ ++ S+    S S
Sbjct: 963  ASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSS 1001



 Score =  100 bits (248), Expect = 3e-20
 Identities = 216/927 (23%), Positives = 319/927 (34%), Gaps = 114/927 (12%)

Query: 1756 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQ 1815
            Q E   G ++A +           +G+  + +GQ S    EG + G     G+     ++
Sbjct: 31   QREEAGGEAAAAAA--------AERGEMKAAAGQES----EGPAVGPPQPLGKELQDGAE 78

Query: 1816 SSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRH--GSGSGQSSGFGH 1873
            S+     G G G + S G  G+     +S G  G     +++      G G G S G G 
Sbjct: 79   SNG----GGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGA 134

Query: 1874 HESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQS 1933
               S+  +     +G G  +               R     +++ ++  + QHG      
Sbjct: 135  PPHSAAAALPPPAYGFGQPYG--------------RSPSAVAAAAAAVFHQQHGGQQSPG 180

Query: 1934 LGHGQHGSGSGQSP--SPSRGRHGSGSGQS---------SSYGPYGSGSGWSSSRGPYES 1982
            L   Q G G G  P   P +  H  G             S+Y P       SS RG    
Sbjct: 181  LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGG-TP 239

Query: 1983 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSH 2042
            GSG ++  G +   S  +S      +SS  SS   Q   A G        G +   +++ 
Sbjct: 240  GSGAAAAAGSKPPPSSSAS------ASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATP 293

Query: 2043 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLG 2102
              +   +S SS  G QG   G   G  Q G            G+G G +  + Q     G
Sbjct: 294  TLNQLLTSPSSARGYQGYPGGDYSGGPQDG------------GAGKGPADMASQ---CWG 338

Query: 2103 ESSGFGHHESSSGQSSSYSQHGSGS-GHSSGYGQHGSRSGQSS-----RGERHGSSSGSS 2156
             ++      ++SG +   S H   S G S G GQ  +R+ Q S      G+      G +
Sbjct: 339  AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGT 398

Query: 2157 SRYG-QHGSGSRQSSGHGRQGSGSG-HSPSR------GRHGSGSGHSS------SHGQHG 2202
            + Y  Q G  S    GHG  G   G  +P R      GR  S  G  S       +GQ G
Sbjct: 399  NPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQG 458

Query: 2203 -SGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS 2261
             SG G+      Y  +S H     Q    S    + + H   S     Q Q         
Sbjct: 459  PSGYGQQGQTPYYNQQSPHPQ--QQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQP 516

Query: 2262 TFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSG 2321
             + Q+ S      S   + S  S +  + Q        P   +  + S +     Q  + 
Sbjct: 517  PYSQQPSQPPHQQSPAPYPSQQSTTQQHPQ------SQPPYSQPQAQSPYQQQQPQQPAP 570

Query: 2322 SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGE 2381
            S  S  +      S QS    + +         +Q   GS  SS+     S+ GQ    E
Sbjct: 571  STLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQ----E 626

Query: 2382 RHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS-GQSPSPSRGRHGSGSGQSSS-YSPYGS 2439
                S  S  S     SGS   L  G  G+ S G S S      G  S  + S +SP+ S
Sbjct: 627  DMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTS 686

Query: 2440 GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS---TSGQS 2496
                   RGP  S  G  + +   +SRSG  S     G+        GQ  S    S   
Sbjct: 687  -PHLPGIRGPSPSPVGSPASVA--QSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQ 743

Query: 2497 SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS 2556
            SS  Q      ++    Q+ S    S+   RQ SG     G    G GS Q  S G +G 
Sbjct: 744  SSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSG-----GQIHTGMGSYQQNSMGSYGP 798

Query: 2557 GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 2616
              G+    G +      ++    +  S+G +   +  G+G      +GQ G     +   
Sbjct: 799  QGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAG---GQMHGQPGIPPYGTLPP 855

Query: 2617 ERHGSSSGSSSHYGQHGSGSRQSSGHG 2643
             R   +S  +  YG + +      G G
Sbjct: 856  GRMSHASMGNRPYGPNMANMPPQVGSG 882



 Score = 90.1 bits (222), Expect = 3e-17
 Identities = 236/1078 (21%), Positives = 357/1078 (33%), Gaps = 147/1078 (13%)

Query: 497  RSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSS 556
            ++ Q  R E  G +A ++++  + G   + + G    G   G  P P     + G+  + 
Sbjct: 26   KAEQQQREEAGGEAAAAAAA--ERGE-MKAAAGQESEGPAVGP-PQPLGKELQDGAESNG 81

Query: 557  SYGPHGYGSGRSSSRGP-YESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGS 615
              G  G GSG      P  ++ +G++       +   +  G G  GSS G  +    H +
Sbjct: 82   GGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAP--PHSA 139

Query: 616  TSGQSSSCGQHGATSGQSSS----------HGQHGSGSSQSSRYGQQGSGSGQSPSRGRH 665
             +         G   G+S S          H QHG   S      Q G G G  P  G  
Sbjct: 140  AAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQ 199

Query: 666  GSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSG 725
             +   H     Q+ S     S+  P       SS  G   GSG ++              
Sbjct: 200  QNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAA------------- 246

Query: 726  YRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSS 785
                GS+   SS +    S+S  SSS+ Q   G+    G    G G+             
Sbjct: 247  ---AGSKPPPSSSA----SASSSSSSFAQQRFGAMGGGGPSAAGGGTPQP---------- 289

Query: 786  GHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHG 845
              +++   +   TS SS+ G+     G  SG G  + G+G+G +   S            
Sbjct: 290  --TATPTLNQLLTSPSSARGYQGYPGGDYSG-GPQDGGAGKGPADMAS------------ 334

Query: 846  STSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPS 905
               G ++++    ++SG +     H   S  +SG G         P       G  +   
Sbjct: 335  QCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQP 394

Query: 906  YGRHGSGSGRSSSSGRHGSGSGQSSGFGHKS---SSGQSSGYTQHGSGSGHSS----SYE 958
            YG      G +  S + G  SG   G G+      S     Y     G   S+    SY 
Sbjct: 395  YG------GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYT 448

Query: 959  QHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGS--RQSLGHGQHGSGSGQSPSPSRGRHGS 1016
            Q     GQ              S YGQ G      Q   H Q          PS+  H  
Sbjct: 449  QQIPPYGQQ-----------GPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQ 497

Query: 1017 GSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 1076
             S Q     P        SS+ PY   S   S   H++S +   S   Q  ++  H  + 
Sbjct: 498  PSYQQQ---PQSQPPQLQSSQPPY---SQQPSQPPHQQSPAPYPS---QQSTTQQHPQSQ 548

Query: 1077 GQHGSTSGQSSSCGQH-----GASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQR 1131
              +     QS    Q       ++  Q +++ Q  S  SQ + Y +Q     Q       
Sbjct: 549  PPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSF 608

Query: 1132 GSGSRQSPSY-GRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 1190
            GS +  +PS     G     + S     S L + SG    +   G   + S   S SG S
Sbjct: 609  GSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSG-SIDDLPMGTEGALSPGVSTSGIS 667

Query: 1191 SGYGQHG--SRSGQSSRGERH--GSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHS-PSR 1245
            S  G+    ++S  S     H  G    S S  G   S ++  SG     +  G+  P R
Sbjct: 668  SSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPR 727

Query: 1246 GRHG------------SGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 1293
               G            S +     + Q      + SS  P  + S      GQ  +G G 
Sbjct: 728  PPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMG- 786

Query: 1294 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHG 1353
              +Y Q+  GS +    GQ+G   G     +          S G  G  +   +G   HG
Sbjct: 787  --SYQQNSMGS-YGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHG 843

Query: 1354 AGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 1413
                  P  G    G    +S G    G   ++   + GSG     G  + +        
Sbjct: 844  QPG--IPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRK-------- 893

Query: 1414 CTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1473
             TQ  + + H ++        G  +  +  G   G+   YGQ G  S         G  +
Sbjct: 894  -TQETAVAMHVAANSIQNRPPGYPNMNQ--GGMMGTGPPYGQ-GINS-------MAGMIN 942

Query: 1474 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSS 1531
             Q P  S G   + +    + SP   G G      P    ++ + G    ES+S +SS
Sbjct: 943  PQGPPYSMGGTMANNSAGMAASPEMMGLG-DVKLTPATKMNNKADGTPKTESKSKKSS 999



 Score = 85.9 bits (211), Expect = 5e-16
 Identities = 204/933 (21%), Positives = 307/933 (32%), Gaps = 126/933 (13%)

Query: 946  QHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYG---QHGSGSRQSLGHGQHGSG 1002
            +   G   +++  + G     + + E  G + G     G   Q G+ S    G G  GSG
Sbjct: 33   EEAGGEAAAAAAAERGEMKAAAGQ-ESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSG 91

Query: 1003 SGQSPSP----SRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSG 1058
             G    P    S G  G     +++      G G  SS G       HS+         G
Sbjct: 92   GGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGV--GAPPHSAAAALPPPAYG 149

Query: 1059 QSSGYGQHGSSSGHSST---HGQHGSTSGQSSSCGQHGASSG-------QSSSHGQHGSG 1108
                YG+  S+   ++    H QHG       +  Q G   G       Q +SH      
Sbjct: 150  FGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPN 209

Query: 1109 SSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFG 1168
               +S Y  + +    +P +      +  SP  G  GSG+  ++ S    S         
Sbjct: 210  HQYNSYYPNRSAYPPPAPAY------ALSSPRGGTPGSGAAAAAGSKPPPSSSA------ 257

Query: 1169 HHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQ-SSRGERHGSSSGSSSHYGQHGSGSR 1227
               S+S  SSS++Q   G+    G    G  + Q ++    +   +  SS  G  G    
Sbjct: 258  ---SASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGG 314

Query: 1228 QSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQH 1287
              SG G Q  G+G  P+          S   G   + +  +++ G  + RS H+ +    
Sbjct: 315  DYSG-GPQDGGAGKGPADMA-------SQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGS 366

Query: 1288 ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGS--GSSQ 1345
              G G   A +   S       + +     G +    Q+G  +G    +G+ G   GS  
Sbjct: 367  SGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQT 426

Query: 1346 SSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHE 1405
               Y     G  QS   G   S +     YGQ G             SG GQ     ++ 
Sbjct: 427  PQRYPMTMQGRAQSAMGGL--SYTQQIPPYGQQGP------------SGYGQQGQTPYYN 472

Query: 1406 SSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLG 1465
              S       Q    S    S   H   S Q     +      S   Y Q  S       
Sbjct: 473  QQSPHPQ--QQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQ-- 528

Query: 1466 HGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRES 1525
                     QSP+P   +  +      S  PY        ++ PY+             S
Sbjct: 529  ---------QSPAPYPSQQSTTQQHPQSQPPYSQ----PQAQSPYQQQQPQQPA----PS 571

Query: 1526 RSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHG--ASSGQSSSHGQHGSGSSQSS 1583
               Q + Y Q  S     + + Q      Q  S    G  ASS  S +  + G      S
Sbjct: 572  TLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLS 631

Query: 1584 GYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESS 1643
               R  S    S        G+  + S G   S SG SSS G+  +     S F  H S 
Sbjct: 632  LQSRPSSLPDLSGSIDDLPMGTEGALSPGV--STSGISSSQGEQSNPA--QSPFSPHTSP 687

Query: 1644 S------------GQSSSYSQHGSGSGHSSGYGQHGSR------SGQSSRGERHGSSSRS 1685
                         G  +S +Q  S SG  S     G++      SGQS     H S ++S
Sbjct: 688  HLPGIRGPSPSPVGSPASVAQ--SRSGPLSPAAVPGNQMPPRPPSGQSD-SIMHPSMNQS 744

Query: 1686 SSR----YGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLG--HSSSHGQHGSGSGRSS 1739
            S      Y Q      Q S      + S + PS G+  +G+G    +S G +G   G+  
Sbjct: 745  SIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYG 804

Query: 1740 SRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSS 1799
             +G Y  +  ++++   +   +G +   +  G+G          G   GQ          
Sbjct: 805  PQGGYPRQPNYNALPNANYPSAGMAGGINPMGAG----------GQMHGQPGIPPYGTLP 854

Query: 1800 TGQSS--SHGQHGSGSSQSSSYGQQGSGSGQSP 1830
             G+ S  S G    G + ++   Q GSG    P
Sbjct: 855  PGRMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887



 Score = 84.3 bits (207), Expect = 2e-15
 Identities = 197/808 (24%), Positives = 267/808 (33%), Gaps = 115/808 (14%)

Query: 2092 SSSGQH--GPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS-RSGQSSRGER 2148
            +++GQ   GP +G     G  E   G  S+    G G+G   G G     ++   + G R
Sbjct: 52   AAAGQESEGPAVGPPQPLGK-ELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPR 110

Query: 2149 HGSSSGSSSRYGQHGSGSRQSSG---HGRQ----------GSGSGHSPSRGRHGSGSGHS 2195
               ++  +   G  G GS    G   H             G   G SPS     + +   
Sbjct: 111  PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFH 170

Query: 2196 SSHG----------QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSG 2245
              HG          Q G G G     GP ++   H     Q+ S   + SAY        
Sbjct: 171  QQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPA-- 228

Query: 2246 HFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQ--GSGSGQSPSRG 2303
             +      G T G S      GS    SSS     S SS SSS+ QQ  G+  G  PS  
Sbjct: 229  -YALSSPRGGTPG-SGAAAAAGSKPPPSSS----ASASSSSSSFAQQRFGAMGGGGPSAA 282

Query: 2304 RHGSGSGHSSS-----YGQHGSGSGWSSSSGRHGSGSGQSSGFGHHE----SSSW-QSSG 2353
              G+    ++           S  G+    G   SG  Q  G G       S  W  ++ 
Sbjct: 283  GGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAA 342

Query: 2354 YTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 2413
                 + SG +     H   S  SS G     +     S      G  +   +G     S
Sbjct: 343  AAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYS 402

Query: 2414 GQSPSPSRGRHGSG-SGQSSSYSPYGSGSGWS---SSRGPYESGSGHSSGLGHRESRS-- 2467
             Q   PS  + G G  GQ     PYGS +      + +G  +S  G   GL + +     
Sbjct: 403  QQQGPPSGPQQGHGYPGQ-----PYGSQTPQRYPMTMQGRAQSAMG---GLSYTQQIPPY 454

Query: 2468 GQS--SGYGQHGSSSGHS--STHGQHGST--SGQSSSCGQHGASSGQSSSHGQHGSGSSQ 2521
            GQ   SGYGQ G +  ++  S H Q      S Q  S   H   S Q     Q     S 
Sbjct: 455  GQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSS 514

Query: 2522 SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHE 2581
               Y +Q S     P H Q  +      S  +    S    S  Q  S   +        
Sbjct: 515  QPPYSQQPS----QPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAP 570

Query: 2582 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGS-----SSHYGQHGSG- 2635
            S+  Q ++Y Q  S     + Y Q      Q    +  GS + S     SS  GQ     
Sbjct: 571  STLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNL 630

Query: 2636 ---SRQSSGHGRQGS------GSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSS------ 2680
               SR SS     GS      G+  + S G   SG+  SSS G+  + +    S      
Sbjct: 631  SLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGI--SSSQGEQSNPAQSPFSPHTSPH 688

Query: 2681 ----RGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF--- 2733
                RGP  S +G  +   Q  SG    +A   +         Q      SGQS +    
Sbjct: 689  LPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGN---------QMPPRPPSGQSDSIMHP 739

Query: 2734 DQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQ-----SSSYGQH 2788
                SS  Q   Y  R     Q S      A S +  S G+  +G G        SYG  
Sbjct: 740  SMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQ 799

Query: 2789 GSGSGQSSGYSQHGSGSGQDGYSYCKGG 2816
            G   G   GY +  + +     +Y   G
Sbjct: 800  GGQYGPQGGYPRQPNYNALPNANYPSAG 827



 Score = 79.3 bits (194), Expect = 5e-14
 Identities = 204/937 (21%), Positives = 286/937 (30%), Gaps = 173/937 (18%)

Query: 1434 SGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP----SRGRHGSGSG 1489
            +GQ S G   G          Q G+ S    G G  GSG G    P    S G  G    
Sbjct: 54   AGQESEGPAVGPPQPLGKEL-QDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPA 112

Query: 1490 QSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSST---H 1546
             +++ +    G G  SS G       HS+         G    YG+  S+   ++    H
Sbjct: 113  LNNNLTEPPGGGGGGSSDGV--GAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFH 170

Query: 1547 GQHGSTSGQSSSCGQHGASSG-------QSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHG 1599
             QHG       +  Q G   G       Q +SH  HG  + Q + Y            + 
Sbjct: 171  QQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSH-DHGFPNHQYNSY------------YP 217

Query: 1600 QRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH 1659
             R +    +P+Y         S   G  GSG   ++G     SSS  +SS          
Sbjct: 218  NRSAYPPPAPAYALS------SPRGGTPGSGAAAAAGSKPPPSSSASASS---------- 261

Query: 1660 SSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQ-------- 1711
                                     SSS + Q   G+    G    G G+ Q        
Sbjct: 262  -------------------------SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLN 296

Query: 1712 ----SPSRGRHGSGL-GHSSSHGQHGSGSGR-------------------SSSRGPYESR 1747
                SPS  R   G  G   S G    G+G+                   +++ G  + R
Sbjct: 297  QLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQR 356

Query: 1748 SGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHG 1807
            S H+ +      G G   A +   S       + +     G +    Q+G  +G    HG
Sbjct: 357  SHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHG 416

Query: 1808 QHGS--GSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 1865
              G   GS     Y     G  QS   G   S +     YGQ G             SG 
Sbjct: 417  YPGQPYGSQTPQRYPMTMQGRAQSAMGGL--SYTQQIPPYGQQGP------------SGY 462

Query: 1866 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQ 1925
            GQ     ++   S       Q    S    S   H   S Q     Q      S   Y Q
Sbjct: 463  GQQGQTPYYNQQS--PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQ 520

Query: 1926 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWS-----SSRGPY 1980
              S                QSP+P   +  +      S  PY      S       + P 
Sbjct: 521  QPSQPPHQ-----------QSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPA 569

Query: 1981 ESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS-ASGQSSSCGQHGASSGQS 2039
             S     +     +S+  Q + Y Q         +    GS AS   S     G     +
Sbjct: 570  PSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMN 629

Query: 2040 SSHGQHGSGSSQSSGY---GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQ 2096
             S     S     SG       G+    SPG    G  S Q      + + S  S  +  
Sbjct: 630  LSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQ--SNPAQSPFSPHTSP 687

Query: 2097 HGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR------SGQSS---RGE 2147
            H PG+      G   S  G  +S +Q  S SG  S     G++      SGQS       
Sbjct: 688  HLPGIR-----GPSPSPVGSPASVAQ--SRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS 740

Query: 2148 RHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGR--HGSGSGHSSSHGQHGSGS 2205
             + SS      Y Q      Q S      + S   PS G+   G GS   +S G +G   
Sbjct: 741  MNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG 800

Query: 2206 GRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 2265
            G+   +G Y  +  ++++   +   +G +   +  G+G          G   GQ      
Sbjct: 801  GQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAG----------GQMHGQPGIPPY 850

Query: 2266 EGSSTGQSS--SHGQHGSGSSQSSSYGQQGSGSGQSP 2300
                 G+ S  S G    G + ++   Q GSG    P
Sbjct: 851  GTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887



 Score = 72.8 bits (177), Expect = 5e-12
 Identities = 144/618 (23%), Positives = 216/618 (34%), Gaps = 97/618 (15%)

Query: 2226 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQ 2285
            Q E   G ++A +           +G+  + +GQ S    EG + G     G+     ++
Sbjct: 31   QREEAGGEAAAAAA--------AERGEMKAAAGQES----EGPAVGPPQPLGKELQDGAE 78

Query: 2286 SSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRH--GSGSGQSSGFGH 2343
            S+     G G G + S G  G+     +S G  G     +++      G G G S G G 
Sbjct: 79   SNG----GGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGA 134

Query: 2344 HESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQS 2403
               S+  +     +G G  +               R     +++ ++  + QHG      
Sbjct: 135  PPHSAAAALPPPAYGFGQPYG--------------RSPSAVAAAAAAVFHQQHGGQQSPG 180

Query: 2404 LGHGQHGSGSGQSP--SPSRGRHGSGSGQS---------SSYSPYGSGSGWSSSRGPYES 2452
            L   Q G G G  P   P +  H  G             S+Y P       SS RG    
Sbjct: 181  LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGG-TP 239

Query: 2453 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH 2512
            GSG ++  G +   S  +S      SSS  S    + G+  G   S    G +   +++ 
Sbjct: 240  GSGAAAAAGSKPPPSSSASA-----SSSSSSFAQQRFGAMGGGGPSAAG-GGTPQPTATP 293

Query: 2513 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLG 2572
              +   +S SS  G QG   G   G  Q G            G+G G +  + Q     G
Sbjct: 294  TLNQLLTSPSSARGYQGYPGGDYSGGPQDG------------GAGKGPADMASQ---CWG 338

Query: 2573 ESSGFGHHESSSGQSSSYSQHGSGS-GHSSGYGQHGSRSGQSS-----RGERHGSSSGSS 2626
             ++      ++SG +   S H   S G S G GQ  +R+ Q S      G+      G +
Sbjct: 339  AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGT 398

Query: 2627 SHYG-QHGSGSRQSSGHGRQGSGSG-QSPSR------GRHGSGLGHSS------SHGQHG 2672
            + Y  Q G  S    GHG  G   G Q+P R      GR  S +G  S       +GQ G
Sbjct: 399  NPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQG 458

Query: 2673 -SGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS 2731
             SG G+      Y  +  H     Q    S    + + H   S     Q Q         
Sbjct: 459  PSGYGQQGQTPYYNQQSPHPQ--QQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQP 516

Query: 2732 TFDQEGSSTGQSSS---YGHRGSGSSQ----SSGYGRHGAGSGQSLSHGRHGSGS--GQS 2782
             + Q+ S      S   Y  + S + Q       Y +  A S       +  + S   Q 
Sbjct: 517  PYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQ 576

Query: 2783 SSYGQHGSGSGQSSGYSQ 2800
            ++Y Q  S   Q + YSQ
Sbjct: 577  AAYPQPQSQQSQQTAYSQ 594



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 152/705 (21%), Positives = 223/705 (31%), Gaps = 79/705 (11%)

Query: 176 SSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHK 235
           S  +G   + +  ++  G     S  +P       G GQ  +     S      G  + +
Sbjct: 334 SQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQ 393

Query: 236 SSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLG 295
              G +    Q G  SG   G+G  G   G  +      +  G + S     S ++Q   
Sbjct: 394 PYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPP 453

Query: 296 HGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGS 355
           +G+QG                   S +GQ G    Y+    H +          Q    S
Sbjct: 454 YGQQG------------------PSGYGQQGQTPYYNQQSPHPQQ---------QQPPYS 486

Query: 356 GQSSGYSKHGSGSGHSSSQGQHGS-TSGQASSSGQHGSSSRQSSSY---GQHESASRHSS 411
            Q    + H   S     Q Q     S Q   S Q      Q S      Q  +  +H  
Sbjct: 487 QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQ 546

Query: 412 GRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYS-SGFGHHES 470
            +  +S    QSP   Q+      S  S Q      +S  S      + YS   F   + 
Sbjct: 547 SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQS----QQTAYSQQRFPPPQE 602

Query: 471 SSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGH 530
            S+ S G     + S  SS  GQ        SR       +GS       G+    S G 
Sbjct: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPM-GTEGALSPGV 661

Query: 531 SRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESR 590
           S  G  S Q         E  +   S + PH         RGP  S  G  + +   +SR
Sbjct: 662 STSGISSSQG--------EQSNPAQSPFSPH-TSPHLPGIRGPSPSPVGSPASVA--QSR 710

Query: 591 SGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYG 650
           SG  S     G+              SGQS S           +    +   + Q  +Y 
Sbjct: 711 SGPLSPAAVPGNQM-------PPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYS 763

Query: 651 QQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQS 710
               GS  SP +   G       SY Q+  G     S GP G   GQ   +G + G  + 
Sbjct: 764 SPQPGSALSPRQPSGGQIHTGMGSYQQNSMG-----SYGPQG---GQ---YGPQGGYPRQ 812

Query: 711 SGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGS 770
             Y+   + +  S+G    G  +   +  + HG            G  SH S G+   G 
Sbjct: 813 PNYNALPNANYPSAGMA--GGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGP 870

Query: 771 GSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHE------SGS 824
              + P +V     SG     G     T  ++   H  + S Q    G          G+
Sbjct: 871 NMANMPPQV----GSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGT 926

Query: 825 GQGYSQH-GSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYG 868
           G  Y Q   S +G  + QG   S  G  +++    ++S +    G
Sbjct: 927 GPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLG 971



 Score = 32.0 bits (71), Expect = 9.0
 Identities = 53/244 (21%), Positives = 81/244 (33%), Gaps = 9/244 (3%)

Query: 2059 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSS 2118
            GSGS Q P   Q  S S       +  + +    S     PG+  S+  G  ++ +  S 
Sbjct: 1137 GSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSD 1196

Query: 2119 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSG 2178
            S  Q  +    + GY    + S    R     +     S     GS    SSG G  G G
Sbjct: 1197 STFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNG-G 1255

Query: 2179 SGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSV--FGQHESGSGHSSA 2236
             G   SR   G G G+ +   +     G     GPY+       +   G   +G+   + 
Sbjct: 1256 MGDPYSRAA-GPGLGNVAMGPRQHYPYG-----GPYDRVRTEPGIGPEGNMSTGAPQPNL 1309

Query: 2237 YSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS 2296
               +     +  S+        Q    D  G+      +       S Q++ Y QQ   S
Sbjct: 1310 MPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVS 1369

Query: 2297 GQSP 2300
              +P
Sbjct: 1370 SPAP 1373


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo
            sapiens]
          Length = 2178

 Score =  105 bits (262), Expect = 6e-22
 Identities = 300/1392 (21%), Positives = 472/1392 (33%), Gaps = 186/1392 (13%)

Query: 468  HESSSEHSSGYTQHGSGS-GHSSGHGQHGSRSGQSSRGE----------RQGSSAGSSSS 516
            H  S+ +S G    G+   G      QHG     ++ G+          + G    +   
Sbjct: 74   HPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPK 133

Query: 517  YGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES 576
             G+   G  +  G    G+       P  G   +   + ++Y    YGS   +S GP   
Sbjct: 134  MGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNY----YGSAAPASGGP--- 186

Query: 577  GSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSH 636
              G  +G    +    QS G G   S+S               +++ G  G+     +SH
Sbjct: 187  --GGRAGPCFDQHGGQQSPGMGMMHSAS---------------AAAAGAPGSMDPLQNSH 229

Query: 637  -GQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVS 695
             G   S  +    Y + G+G G     G  G   G  S  G  G G+G   +    G+V+
Sbjct: 230  EGYPNSQCNHYPGYSRPGAGGG-----GGGGGGGGGGSGGGGGGGGAGAGGAGA--GAVA 282

Query: 696  GQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQH 755
              ++     +G G   GY    +G    S  R+ G   G        G++S   ++ G  
Sbjct: 283  AAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQG--GGMMMGPGGGGAASLSKAAAGSA 340

Query: 756  GSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCS------SSCGHYES 809
              G  + +G  +  SG+  + +++    S    S  G +   +S S      S      +
Sbjct: 341  AGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAA 400

Query: 810  GSGQASGFGQHESGSGQGY---SQHGSASGHFS----------SQGRHGSTSGQSSSSGQ 856
             +G A+G  Q  +G G G    +Q+ +AS  ++          S G  G T G+S  S  
Sbjct: 401  AAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPM 460

Query: 857  HDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSG-SGQSPSYGRHGSGSGR 915
                  +   YG   +          +  GS   PG  +   G  G++P     G+ +G 
Sbjct: 461  DPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTP-----GAMAGM 515

Query: 916  SSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGS 975
                 +     GQ    G+    GQ   Y+Q           +   S+S Q  + +Q  S
Sbjct: 516  QYPQQQMPPQYGQQGVSGY-CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMS 574

Query: 976  SSGSSSSYGQHGSGSRQSLGHGQ---HGSGSGQSPSPSRGRHGSGS------GQSSSYGP 1026
              G       +G+ S+  L  G+         Q   PS     SGS      G  ++   
Sbjct: 575  QEG-------YGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSS 627

Query: 1027 YRSGSGWSSSRG----PYES-----GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG 1077
              S SG +SS+G    P +S      S H S +    S S   S  G + S SG  S   
Sbjct: 628  AVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPAS 687

Query: 1078 QHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG--SGSGQSPGHGQRGSGS 1135
              GS         Q   S  +SSSH       SQS     +G  +G+ ++P   Q G   
Sbjct: 688  IPGSQMPP-----QPPGSQSESSSH----PALSQSPMPQERGFMAGTQRNPQMAQYGP-Q 737

Query: 1136 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSG-HSSGYG 1194
            +  PS   H S  G+  +          S  +G   S  G   +YS+  + SG  S+ Y 
Sbjct: 738  QTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYS 797

Query: 1195 QHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSG------HGRQGSGSGHSPSRGRH 1248
              G   G S+  + HG   G S   G    G   S+G       G   S +  SP   + 
Sbjct: 798  GPGPGMGISANNQMHG--QGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQ 855

Query: 1249 GS-GLGHS----SSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG-SGHSSAYSQHGS 1302
            G  G+G      +   Q  + +   ++    +SR G  S  G ++SG    SS YSQ  +
Sbjct: 856  GGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQG--SFPGMNQSGLMASSSPYSQPMN 913

Query: 1303 GSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSR 1362
             S    +  Q    S   +  +   +S G +       S             G+ Q  S+
Sbjct: 914  NSSSLMNT-QAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESK 972

Query: 1363 GRHGSGSGHSS-------SYGQHGSGSGW----SSSSGRHGSGSGQSSGFGHHESSSWQS 1411
             +  S S  +          G       W     +     GS        G      ++ 
Sbjct: 973  SKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRL 1032

Query: 1412 SGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGS 1471
              C +   G    +  ++    +   + G    ++S     Y Q+       +       
Sbjct: 1033 YVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIER----- 1087

Query: 1472 GSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGL----GHRESRS 1527
              G+ P P     G    Q     P  + SG  S +GP    S+ S+ +    G  +  +
Sbjct: 1088 --GEEPPPEVFSTGDTKKQPKLQPPSPANSG--SLQGPQTPQSTGSNSMAEVPGDLKPPT 1143

Query: 1528 GQSSGYGQ-HGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG 1586
              S+ +GQ      G SST   H   S  S S      S   ++ + Q   G S     G
Sbjct: 1144 PASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQ---GMSMPDVMG 1200

Query: 1587 RQGSGSGQSPGHGQRGSGSRQSP--SYGRHGSGS-----GRSSSSGQHGSGLGESSGFGH 1639
            R      + P  G R       P  + G+  + S      +S S      G+G+   F +
Sbjct: 1201 RMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPY 1260

Query: 1640 HESSSGQSSSYSQHGSGSGHSSGYGQHGSRS----GQSSRGERH-------GSSSRSSSR 1688
              S   +   Y Q   G G  SG   +G        Q    +RH        +       
Sbjct: 1261 GASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDM 1320

Query: 1689 YGQHGSGSRQS--SGHGRQGSGSGQSPSRGRHG--------SGLGHSSSHG----QHGSG 1734
            Y    S  +Q   + +G   SG  + P +G++          G G   +HG      G  
Sbjct: 1321 YNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGP 1380

Query: 1735 SGRSSSRGPYES 1746
               SSS GP ++
Sbjct: 1381 LQSSSSEGPQQN 1392



 Score =  100 bits (248), Expect = 3e-20
 Identities = 220/965 (22%), Positives = 325/965 (33%), Gaps = 116/965 (12%)

Query: 233  QHKSSSGQSSGYSQHGSGS-GHSSGYGQHGSRSGQSSRGE----------RHRSSSGSSS 281
            QH  S+  S G +  G+   G      QHG     ++ G+          +      +  
Sbjct: 73   QHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPP 132

Query: 282  SYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESG 341
              G+   G  +  G G    G++Q P  V  G G   +     +  GS+   S G    G
Sbjct: 133  KMGEPAGGRYEHPGLG--ALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGG---PG 187

Query: 342  SGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSR-QSSSY 400
                  F QH        G    G G  HS+S          A+++G  GS    Q+S  
Sbjct: 188  GRAGPCFDQH-------GGQQSPGMGMMHSAS----------AAAAGAPGSMDPLQNSHE 230

Query: 401  GQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTG------FGRSSSSGP 454
            G   S   H  G  +  +G G   G G  G GSG     G  G G         ++++  
Sbjct: 231  GYPNSQCNHYPGYSRPGAGGGGGGGGGG-GGGSGGGGGGGGAGAGGAGAGAVAAAAAAAA 289

Query: 455  YVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSS 514
              +G G   G+G   +     S   Q G G     G G   S S  ++     GS+AG  
Sbjct: 290  AAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAA-----GSAAGGF 344

Query: 515  SSY---GQHGSGSRQSLGHSRHGSGSGQSPSPSR----GRHESGSRQSSSYGPHGYGSGR 567
              +    QH SG+  +L           SPSP      G +   S  S+   P      +
Sbjct: 345  QRFAGQNQHPSGATPTLNQLL------TSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398

Query: 568  SSSRGPYESGSGHSSGLGHQESRSGQ----SSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 623
            +++ G    G   ++G+G  +    Q    S  +      S  + + G  G T G+S   
Sbjct: 399  AAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGS 458

Query: 624  GQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSG 683
                    +   +G   +  SQ  +      GS   P   R+       +     G+ +G
Sbjct: 459  PMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTP----GAMAG 514

Query: 684  WSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHG 743
                        GQ    G+    GQ   YSQ           +   S+S Q  + +Q  
Sbjct: 515  MQYPQQQMPPQYGQQGVSGY-CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDM 573

Query: 744  SSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSS 803
            S  G       +G+ S      G+      +   + R  S    S S     +GT  + S
Sbjct: 574  SQEG-------YGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLS 626

Query: 804  CGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQ 863
                 S SG  S  G   + +   +S H  AS H SS     S S   S  G + S SG 
Sbjct: 627  SA--VSASGSTSSQGDQSNPAQSPFSPH--ASPHLSSIPGGPSPSPVGSPVGSNQSRSGP 682

Query: 864  SSSY-------------GQHESASHHASGRGRHGSGSGQSPGHGQRG--SGSGQSPSYGR 908
             S                Q ES+SH A           QSP   +RG  +G+ ++P   +
Sbjct: 683  ISPASIPGSQMPPQPPGSQSESSSHPA---------LSQSPMPQERGFMAGTQRNPQMAQ 733

Query: 909  HGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSS 968
            +G      S S     G    +G      S  S  Y    S  G   +Y +  + SG  S
Sbjct: 734  YGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPS 793

Query: 969  RS-EQHGSSSGSSSSYGQHGSGSRQSLGHGQHG----SGSGQSPSPSR--GRHGSGSGQS 1021
             S    G   G S++   HG G  Q  G    G    +G    P P        S  G S
Sbjct: 794  ASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMS 853

Query: 1022 SSYGPYRSGSGWSSSRGPYESGSG-HSSGLGHRESRSGQSSGYGQHG--SSSGHSSTHGQ 1078
               GP       + +R   E+ +    +     +SR G   G  Q G  +SS   S    
Sbjct: 854  QQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMN 913

Query: 1079 HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG---SGSGQSPGHGQRGSGS 1135
            + S+   + +     A +  +SS    G     S G  +        G+  G  Q  S S
Sbjct: 914  NSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKS 973

Query: 1136 RQSPS 1140
            ++S S
Sbjct: 974  KKSSS 978



 Score = 96.3 bits (238), Expect = 4e-19
 Identities = 179/795 (22%), Positives = 277/795 (34%), Gaps = 74/795 (9%)

Query: 1392 GSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSS 1451
            G G      F ++  S+  +SG    G G      ++QHG +      G  H +S+ ++ 
Sbjct: 163  GGGPAAVPEFNNYYGSAAPASG----GPGGRAGPCFDQHGGQQSPGM-GMMHSASAAAAG 217

Query: 1452 SYGQHG--SGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGP 1509
            + G       S +   + Q     G S  P  G  G G G     S  G G G + + G 
Sbjct: 218  APGSMDPLQNSHEGYPNSQCNHYPGYS-RPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGA 276

Query: 1510 YESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQS 1569
                 + ++      +  G   GYG  GSS+G+           G     G  GA+S   
Sbjct: 277  GAGAVAAAAAAAAAAAGGGGGGGYG--GSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSK 334

Query: 1570 SSHGQHGSGSSQSSGYGRQGSGSG-------QSPGHGQRGSGSR-----------QSPSY 1611
            ++ G    G  + +G  +  SG+         SP    R  G               PS 
Sbjct: 335  AAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQ 394

Query: 1612 GRHGSGSGRSSSSGQH---GSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS 1668
             +  + +  +++ GQ    G GLG+  G  +  +S   +++  +    S  +   G  G 
Sbjct: 395  PQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQR----SHPAMSPGTPGP 450

Query: 1669 RSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSH 1728
              G+S          +    YG   +   Q         GS   P   R+  G+   +  
Sbjct: 451  TMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTP- 509

Query: 1729 GQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG 1788
               G+ +G    +     + G   V G  +   G    YSQ      H   Q Q+  +  
Sbjct: 510  ---GAMAGMQYPQQQMPPQYGQQGVSGYCQ--QGQQPYYSQQPQ-PPHLPPQAQYLPSQS 563

Query: 1789 QSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQH 1848
            Q     Q      Q  S   +G+ S    + G+          + R  S    S S    
Sbjct: 564  QQRYQPQ------QDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL 617

Query: 1849 GSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSS 1908
             +G+  + SS    SGS  S G    + S+   S ++ H   S H SS     S S   S
Sbjct: 618  PTGTEATLSSAVSASGSTSSQG----DQSNPAQSPFSPH--ASPHLSSIPGGPSPSPVGS 671

Query: 1909 RGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS----GQSPSPSRGRHGSGSGQSSSY 1964
                + S SG  S     GS         Q  S S     QSP P      +G+ ++   
Sbjct: 672  PVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQM 731

Query: 1965 GPYG-SGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSAS 2023
              YG   +G S S  P   G  H+     ++S S  S  YG   S  G    + +  + S
Sbjct: 732  AQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNS--SGTYGPQMSQYGPQGNYSRPPAYS 789

Query: 2024 G-QSSSCGQHGASSGQSSSHGQHGSGSSQSSG---YGRQGSGSGQS-PGHGQRGSGSRQS 2078
            G  S+S    G   G S+++  HG G SQ  G    GR  S   Q+ P  G   S +  S
Sbjct: 790  GVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSS 849

Query: 2079 PSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS 2138
            P   + G G G        GP +   +      +++   ++ +   S  G   G  Q G 
Sbjct: 850  PGMSQQG-GPGM-------GPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGL 901

Query: 2139 RSGQSSRGERHGSSS 2153
             +  S   +   +SS
Sbjct: 902  MASSSPYSQPMNNSS 916



 Score = 95.5 bits (236), Expect = 7e-19
 Identities = 183/799 (22%), Positives = 273/799 (34%), Gaps = 79/799 (9%)

Query: 1801 GQSSSHGQHGSGSSQSSSYGQQ-----------GSGSGQSPSRGRHGSGSGHSSSYGQHG 1849
            G      QHG G+  S++ GQ            G      P  G    G       G  G
Sbjct: 93   GPDMEQPQHG-GAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALG 151

Query: 1850 SGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 1909
            +     +  G  G G      F ++  S+  +SG    G G      ++QHG +      
Sbjct: 152  TQQPPVAVPGG-GGGPAAVPEFNNYYGSAAPASG----GPGGRAGPCFDQHGGQQSPGM- 205

Query: 1910 GEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGS 1969
            G  H +S+ ++ + G       Q+   G   S     P  SR   G G G     G    
Sbjct: 206  GMMHSASAAAAGAPGS--MDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSG 263

Query: 1970 GSGWSSSRGPYESGSGH-SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSS 2028
            G G     G   +G+G  ++      + +G   G G  GSS+G+           G    
Sbjct: 264  GGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMG 323

Query: 2029 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSG-------QSPGHGQRGSGSR----- 2076
             G  GA+S   ++ G    G  + +G  +  SG+         SP    R  G       
Sbjct: 324  PGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYS 383

Query: 2077 ------QSPSYGRHGSGSGRSSSSGQH---GPGLGESSGFGHHESSSGQSSSYSQHGSGS 2127
                    PS  +  + +  +++ GQ    G GLG+  G  +  +S   +++  +    S
Sbjct: 384  SPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQR----S 439

Query: 2128 GHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGR 2187
              +   G  G   G+S               YG   +   Q         GS   P   R
Sbjct: 440  HPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQR 499

Query: 2188 HGSG-SGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGH 2246
            +  G  G +      G+ +G    +     + G   V G  +   G    YSQ      H
Sbjct: 500  YPIGIQGRTP-----GAMAGMQYPQQQMPPQYGQQGVSGYCQ--QGQQPYYSQQPQ-PPH 551

Query: 2247 FCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHG 2306
               Q Q+  +  Q     Q      Q  S   +G+ S    + G+          + R  
Sbjct: 552  LPPQAQYLPSQSQQRYQPQ------QDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPS 605

Query: 2307 SGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSS 2366
            S    S S     +G+  + SS    SGS  S G    + S+   S ++ H   S H SS
Sbjct: 606  SLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQG----DQSNPAQSPFSPH--ASPHLSS 659

Query: 2367 YEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS----GQSPSPSRG 2422
                 S S   S    + S SG  S     GS         Q  S S     QSP P   
Sbjct: 660  IPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQER 719

Query: 2423 RHGSGSGQSSSYSPYG-SGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG 2481
               +G+ ++   + YG   +G S S  P   G  H+     ++S S  S  YG   S  G
Sbjct: 720  GFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNS--SGTYGPQMSQYG 777

Query: 2482 HSSTHGQHGSTSG-QSSSCGQHGASSGQSSSHGQHGSGSSQSSG---YGRQGSGSGQS-P 2536
                + +  + SG  S+S    G   G S+++  HG G SQ  G    GR  S   Q+ P
Sbjct: 778  PQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRP 837

Query: 2537 GHGQRGSGSRQSPSYGRHG 2555
              G   S +  SP   + G
Sbjct: 838  FPGNMSSMTPSSPGMSQQG 856



 Score = 89.0 bits (219), Expect = 6e-17
 Identities = 234/1041 (22%), Positives = 345/1041 (33%), Gaps = 186/1041 (17%)

Query: 1516 HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG----STSGQSSSCGQHGASSGQSSS 1571
            H+  L H  +   Q + + Q            Q      S +      G      G    
Sbjct: 38   HAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDME 97

Query: 1572 HGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGL 1631
              QHG     ++G      G    PG           P   + G         G+   G 
Sbjct: 98   QPQHGGAKDSAAG------GQADPPG----------PPLLSKPGDEDDAPPKMGEPAGGR 141

Query: 1632 GESSGFGHHESSSGQSSSYSQHGSGSG------HSSGYGQHGSRSGQSSRGERHGSSSRS 1685
             E  G G   +   Q    +  G G G       ++ YG     SG        G   R+
Sbjct: 142  YEHPGLG---ALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG--------GPGGRA 190

Query: 1686 SSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYE 1745
               + QHG                 QSP     G G+ HS+S     + +G   S  P +
Sbjct: 191  GPCFDQHGGQ---------------QSP-----GMGMMHSAS----AAAAGAPGSMDPLQ 226

Query: 1746 SRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 1805
            +     S  G   S   H   YS+ G+G G     G  G + G        G   G + +
Sbjct: 227  N-----SHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGG--------GGGGGGAGA 273

Query: 1806 HGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 1865
             G      + +++     +G G     G   +G G  SS  Q G G       G  G+ S
Sbjct: 274  GGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGG--GAAS 331

Query: 1866 GQSSGFGHHESSSWQSSGYTQHGSGS----------------GHSSSYEQHGSRSGQS-- 1907
               +  G       + +G  QH SG+                 +  SY ++ S S     
Sbjct: 332  LSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPP 391

Query: 1908 -SRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGP 1966
             S+ +   +++G+++   Q  +G    LG       +  SP+ +  +  S    S     
Sbjct: 392  PSQPQSQAAAAGAAAGGQQAAAG--MGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPG 449

Query: 1967 YGSGSGWSSSRGPYESGSGHSSGLGHR-ESRSGQSSGY--GQHGSSSGHSSTHGQHGSAS 2023
               G    S   P         G+G    S+  QSS Y  G +G         G  G   
Sbjct: 450  PTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTP 509

Query: 2024 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQS---------------PGH 2068
            G  +  G           +GQ G      SGY +QG     S               P  
Sbjct: 510  G--AMAGMQYPQQQMPPQYGQQGV-----SGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQ 562

Query: 2069 GQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSG 2128
             Q+    +Q  S   +G+ S    + G+  P   + +       SS    S S     +G
Sbjct: 563  SQQRYQPQQDMSQEGYGTRSQPPLAPGK--PNHEDLNLIQQERPSSLPDLSGSIDDLPTG 620

Query: 2129 HSSGYGQHGSRSGQ-SSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGR 2187
              +      S SG  SS+G++   S+ + S +  H S    S   G   S  G SP  G 
Sbjct: 621  TEATLSSAVSASGSTSSQGDQ---SNPAQSPFSPHASPHLSSIPGGPSPSPVG-SPV-GS 675

Query: 2188 HGSGSGHSSSHGQHGS-------GSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQH 2240
            + S SG  S     GS       GS   SS  P  S+S      G   +G+  +   +Q+
Sbjct: 676  NQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG-FMAGTQRNPQMAQY 734

Query: 2241 GSGSGHFCSQGQHGSTSGQS----STFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS 2296
            G       S   H S  GQ     S+F Q  SS          G+   Q S YG QG+ S
Sbjct: 735  GPQQTG-PSMSPHPSPGGQMHAGISSFQQSNSS----------GTYGPQMSQYGPQGNYS 783

Query: 2297 GQSPSRGRHGSGSG-HSSSYGQHGSGSGWSSSSGRHGSGSGQSSG---FGHHESSSWQSS 2352
                   R  + SG  S+SY   G G G S+++  HG G  Q  G    G   S+  Q+ 
Sbjct: 784  -------RPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR 836

Query: 2353 GYTQHGSGSGHSS--SYEQHGSRSG--QSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQ 2408
             +  + S    SS    +Q G   G    +   +   ++ +      + + SRQ    G 
Sbjct: 837  PFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGM 896

Query: 2409 HGSGSGQSPSP-SRGRHGSGSGQSSSYSPY----------GSGSGWSSSRGPYES----- 2452
            + SG   S SP S+  + S S  ++   PY           +  G +    P ES     
Sbjct: 897  NQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLP 956

Query: 2453 --GSGHSSGLGHRESRSGQSS 2471
                G   G    ES+S +SS
Sbjct: 957  LKADGKEEGTPQPESKSKKSS 977



 Score = 88.6 bits (218), Expect = 8e-17
 Identities = 300/1379 (21%), Positives = 447/1379 (32%), Gaps = 193/1379 (13%)

Query: 1422 GHSSSYEQHGSRSGQSSRGE----------RHGSSSGSSSSYGQHGSGSRQSLGHGQHGS 1471
            G      QHG     ++ G+          + G    +    G+   G  +  G G    
Sbjct: 93   GPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLG--AL 150

Query: 1472 GSGQSPSPSRGRHGSGSGQSSSYSPYGSGS----GWSSSRGPY--ESGSSHSSGLGHRES 1525
            G+ Q P    G  G  +      + YGS +    G     GP   + G   S G+G   S
Sbjct: 151  GTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHS 210

Query: 1526 RSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQH-GASSGQSSSHGQHGSGSSQSSG 1584
             S  ++G    GS     ++H  +      +S C  + G S   +   G  G G    SG
Sbjct: 211  ASAAAAG--APGSMDPLQNSHEGY-----PNSQCNHYPGYSRPGAGGGGGGGGGGGGGSG 263

Query: 1585 YGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS 1644
             G  G G+G + G G     +  + +    G G G                G+G   +  
Sbjct: 264  GGGGGGGAG-AGGAGAGAVAAAAAAAAAAAGGGGG---------------GGYGGSSAGY 307

Query: 1645 GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQ------ 1698
            G  SS  Q G G     G G   S S +++ G   G   R + +  QH SG+        
Sbjct: 308  GVLSSPRQQGGGMMMGPGGGGAASLS-KAAAGSAAGGFQRFAGQ-NQHPSGATPTLNQLL 365

Query: 1699 SSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHE 1758
            +S      S  G  P      +     S      + +G ++      +  G     G   
Sbjct: 366  TSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQY 425

Query: 1759 SGSGHSSAYSQHGSGSGHFCSQGQHGSTSG--QSSTFDQEGSSTGQSSSHGQHGSGSSQS 1816
            + +  + A +Q  S      S G  G T G  Q S  D       Q    G +     Q 
Sbjct: 426  AAASPAWAAAQQRSHPA--MSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQ 483

Query: 1817 SSYGQQGSGSGQSPSR---GRHGSGSGHSS-----------SYGQHGSGSGWSSSSGRHG 1862
            SS    GS     P R   G  G   G  +            YGQ G           + 
Sbjct: 484  SSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYY 543

Query: 1863 SGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRS------GQSSRGEQHGSS 1916
            S   Q     H    +      +Q         S E +G+RS      G+ +  + +   
Sbjct: 544  SQQPQPP---HLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQ 600

Query: 1917 SGSSSSYGQHGSGSRQSLGHGQHGS-GSGQSPSPSRGRHGSGSGQSSS-YGPYGSGSGWS 1974
                SS     SGS   L  G   +  S  S S S    G  S  + S + P+ S    S
Sbjct: 601  QERPSSLPDL-SGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSS 659

Query: 1975 SSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGS--------SSGHSSTHGQHGSASGQS 2026
               GP  S  G  S +G  +SRSG  S     GS        S   SS+H     A  QS
Sbjct: 660  IPGGPSPSPVG--SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSH----PALSQS 713

Query: 2027 SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHG- 2085
                + G  +G           + Q + YG Q +G   SP           SP    H  
Sbjct: 714  PMPQERGFMAGTQR--------NPQMAQYGPQQTGPSMSP---------HPSPGGQMHAG 756

Query: 2086 -SGSGRSSSSGQHGPGLGESSGFGHHES----SSGQSSSYSQHGSGSGHSSGYGQHGSRS 2140
             S   +S+SSG +GP + +    G++      S   S+SYS  G G G S+    HG   
Sbjct: 757  ISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGP 816

Query: 2141 GQSSRGERHG--SSSGSSSR--YGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSS 2196
             Q       G   S+G  +R   G   S +  S G  +QG G G  P            +
Sbjct: 817  SQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQG-GPGMGPPMPT-------VN 868

Query: 2197 SHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG-SGHSSAYSQHGSGSGHFCSQGQHGS 2255
               Q  + +   ++    +SR G  S  G ++SG    SS YSQ  + S    +  Q   
Sbjct: 869  RKAQEAAAAVMQAAANSAQSRQG--SFPGMNQSGLMASSSPYSQPMNNSSSLMNT-QAPP 925

Query: 2256 TSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSS-- 2313
             S   +  +   +S G +       S          +  G+ Q  S+ +  S S  +   
Sbjct: 926  YSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEK 985

Query: 2314 -----SYGQHGSGSGW----SSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHS 2364
                   G       W     +     GS        G      ++     +   G    
Sbjct: 986  ITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQV 1045

Query: 2365 SSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH 2424
            +  ++    +   + G    ++S     Y Q+       +  G       + P P     
Sbjct: 1046 NKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERG-------EEPPPEVFST 1098

Query: 2425 GSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGL----GHRESRSGQSSGYGQ-HGSS 2479
            G    Q     P  + SG  S +GP    S  S+ +    G  +  +  S+ +GQ     
Sbjct: 1099 GDTKKQPKLQPPSPANSG--SLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQ 1156

Query: 2480 SGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHG 2539
             G SST   H   S  S S      S   ++ + Q   G S     GR      + P  G
Sbjct: 1157 GGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQ---GMSMPDVMGRMPYEPNKDPFGG 1213

Query: 2540 QRGSGSRQSP--SYGRHGSGS-----GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ 2592
             R       P  + G+  + S      +S S      G+G+   F +  S   +   Y Q
Sbjct: 1214 MRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQ 1273

Query: 2593 HGSGSGHSSGYGQHGSRS----GQSSRGERH-------GSSSGSSSHYGQHGSGSRQS-- 2639
               G G  SG   +G        Q    +RH        +       Y    S  +Q   
Sbjct: 1274 QYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMY 1333

Query: 2640 SGHGRQGSGSGQSPSRGRHG--------SGLGHSSSHG----QHGSGSGRSSSRGPYES 2686
            + +G   SG  + P +G++          G G   +HG      G     SSS GP ++
Sbjct: 1334 NQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQN 1392



 Score = 86.7 bits (213), Expect = 3e-16
 Identities = 207/912 (22%), Positives = 298/912 (32%), Gaps = 125/912 (13%)

Query: 1887 HGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQS 1946
            H   + H   +     +  Q  + +Q            QH   +  SLG G  G      
Sbjct: 35   HHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLG-GAGGGAPQPG 93

Query: 1947 PSPSRGRHG-----SGSGQSSSYGPY-----GSGSGWSSSRGPYESGSGHSSGLGHRESR 1996
            P   + +HG     +  GQ+   GP      G         G    G     GLG   ++
Sbjct: 94   PDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQ 153

Query: 1997 SGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCG--------QHGASSGQSSSHGQHGSG 2048
                +  G  G  +     +  +GSA+  S   G        QHG    QS   G   S 
Sbjct: 154  QPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQ--QSPGMGMMHSA 211

Query: 2049 SSQSSGYGRQGSGSGQSPGH-GQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGF 2107
            S+ ++G    GS       H G   S     P Y R G+G G     G  G   G   G 
Sbjct: 212  SAAAAG--APGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG 269

Query: 2108 GHHESSSGQ-----SSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQH 2162
            G     +G      +++ +   +G G   GYG  GS +G            G     G  
Sbjct: 270  GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYG--GSSAGYGVLSSPRQQGGGMMMGPGGG 327

Query: 2163 GSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHS- 2221
            G+ S   +  G    G      + +H SG+  + +           S  G Y   S  S 
Sbjct: 328  GAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSA 387

Query: 2222 -----SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSH 2276
                 S      + +G ++   Q  +G G     G   + +  +    Q+ S    S   
Sbjct: 388  PPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGT 447

Query: 2277 GQHGSGSSQSSSYGQ------QGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGR 2330
                 G SQ S          Q  G G +P      S      SYG  G         G 
Sbjct: 448  PGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQR---YPIGI 504

Query: 2331 HGSGSGQSSGFGHHESSSWQS------SGYTQHGSGSGHSS---------------SYEQ 2369
             G   G  +G  + +            SGY Q G    +S                S  Q
Sbjct: 505  QGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQ 564

Query: 2370 HGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSG 2429
               +  Q    E +G+ S    + G+        +   +  S    S S      G+ + 
Sbjct: 565  QRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEAT 624

Query: 2430 QSSSYSPYGSGSGWSSSRGPYES-----GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 2484
             SS+ S  GS S       P +S      S H S +    S S   S  G + S SG  S
Sbjct: 625  LSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPIS 684

Query: 2485 THGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG-- 2542
                 GS         Q   S  +SSSH                     QSP   +RG  
Sbjct: 685  PASIPGSQMPP-----QPPGSQSESSSH-----------------PALSQSPMPQERGFM 722

Query: 2543 SGSRQSPS---YGRHGSGSGRS---SSSGQHGSGL-----GESSG-FGHHESSSGQSSSY 2590
            +G++++P    YG   +G   S   S  GQ  +G+       SSG +G   S  G   +Y
Sbjct: 723  AGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNY 782

Query: 2591 SQHGSGSG-HSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSG------HG 2643
            S+  + SG  S+ Y   G   G S+  + HG   G S   G    G   S+G       G
Sbjct: 783  SRPPAYSGVPSASYSGPGPGMGISANNQMHG--QGPSQPCGAVPLGRMPSAGMQNRPFPG 840

Query: 2644 RQGSGSGQSPSRGRHGS-GLGHS----SSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHE 2698
               S +  SP   + G  G+G      +   Q  + +   ++    +SR G  S  G ++
Sbjct: 841  NMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQG--SFPGMNQ 898

Query: 2699 SG-SGHSSAYSQ 2709
            SG    SS YSQ
Sbjct: 899  SGLMASSSPYSQ 910



 Score = 84.0 bits (206), Expect = 2e-15
 Identities = 185/854 (21%), Positives = 275/854 (32%), Gaps = 111/854 (12%)

Query: 1999 QSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 2058
            Q   +  H     H + H  H  A  Q  +  Q      Q     Q       S+     
Sbjct: 24   QQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLG 83

Query: 2059 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH---GPGLGESSGFGHHESSSG 2115
            G+G G +P  G       + P +G    G+  S++ GQ    GP L    G         
Sbjct: 84   GAGGG-APQPGP----DMEQPQHG----GAKDSAAGGQADPPGPPLLSKPG-----DEDD 129

Query: 2116 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQ 2175
                  +   G     G G  G++    +     G  +        +GS +  S G G +
Sbjct: 130  APPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGR 189

Query: 2176 GSGSGHSPSRGRHGS--GSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 2233
                   P   +HG     G    H    + +G   S  P ++     S  G   S   H
Sbjct: 190  AG-----PCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQN-----SHEGYPNSQCNH 239

Query: 2234 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQG 2293
               YS+ G+G G     G  G + G        G   G + + G      + +++     
Sbjct: 240  YPGYSRPGAGGGGGGGGGGGGGSGG--------GGGGGGAGAGGAGAGAVAAAAAAAAAA 291

Query: 2294 SGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 2353
            +G G     G   +G G  SS  Q G G       G  G+ S   +  G       + +G
Sbjct: 292  AGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGG--GAASLSKAAAGSAAGGFQRFAG 349

Query: 2354 YTQHGSGS----------------GHSSSYEQHGSRSGQS---SRGERHGSSSGSSSSYG 2394
              QH SG+                 +  SY ++ S S      S+ +   +++G+++   
Sbjct: 350  QNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ 409

Query: 2395 QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGS 2454
            Q  +G    LG       +  SP+ +  +  S    S        G    S   P     
Sbjct: 410  QAAAG--MGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467

Query: 2455 GHSSGLGHR-ESRSGQSSGY--GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSS 2511
                G+G    S+  QSS Y  G +G         G  G T G  +  G           
Sbjct: 468  PQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPG--AMAGMQYPQQQMPPQ 525

Query: 2512 HGQHGSGSSQSSGYGRQGSGSGQS---------------PGHGQRGSGSRQSPSYGRHGS 2556
            +GQ G      SGY +QG     S               P   Q+    +Q  S   +G+
Sbjct: 526  YGQQGV-----SGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGT 580

Query: 2557 GSGRSSSSG------------QHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYG 2604
             S    + G            +  S L + SG    +  +G  ++ S   S SG +S  G
Sbjct: 581  RSQPPLAPGKPNHEDLNLIQQERPSSLPDLSG-SIDDLPTGTEATLSSAVSASGSTSSQG 639

Query: 2605 QHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGH 2664
               + +   S    H S   SS   G   S S   S  G   S SG        GS +  
Sbjct: 640  DQSNPA--QSPFSPHASPHLSSIPGGP--SPSPVGSPVGSNQSRSGPISPASIPGSQMPP 695

Query: 2665 SSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHG 2724
                 Q  S S  + S+ P     G  +       G+  +   +Q+G       S   H 
Sbjct: 696  QPPGSQSESSSHPALSQSPMPQERGFMA-------GTQRNPQMAQYGPQQTG-PSMSPHP 747

Query: 2725 STSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSG-QSLSHGRHGSGSGQSS 2783
            S  GQ          +  S +YG + S       Y R  A SG  S S+   G G G S+
Sbjct: 748  SPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISA 807

Query: 2784 SYGQHGSGSGQSSG 2797
            +   HG G  Q  G
Sbjct: 808  NNQMHGQGPSQPCG 821



 Score = 83.6 bits (205), Expect = 3e-15
 Identities = 150/718 (20%), Positives = 229/718 (31%), Gaps = 103/718 (14%)

Query: 169 HNSYSGQSSSYGEQN--SDSHQSSGRGQCGSGSGQS-PNYGQHGSGSGQSSSNDTHGSGS 225
           H++ +  + + G  +   +SH+     QC    G S P  G  G G G        G G 
Sbjct: 209 HSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGG 268

Query: 226 GQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ 285
           G +        +   ++  +   +G G   GYG  GS +G        +   G     G 
Sbjct: 269 GGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYG--GSSAGYGVLSSPRQQGGGMMMGPGG 326

Query: 286 HGSGSRQSLGHGRQGSGSRQSPSHVRHGSGS----------------GHSSSHGQHGSGS 329
            G+ S      G    G ++     +H SG+                 +  S+ ++ S S
Sbjct: 327 GGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPS 386

Query: 330 ----------SYSYSRGHYESGSGQTSGFGQHESGSGQ----SSGYSKHGSGSGHSSSQG 375
                     S + + G    G    +G G  +    Q    S  ++     S  + S G
Sbjct: 387 APPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPG 446

Query: 376 QHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGS--------------G 421
             G T G++  S       ++   YG   +          +  GS              G
Sbjct: 447 TPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQG 506

Query: 422 QSPG--HGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVS----------GSGYSSGFGHHE 469
           ++PG   G +       P  GQ G          PY S           + Y        
Sbjct: 507 RTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQR 566

Query: 470 SSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLG 529
              +       +G+ S      G+         + ER  S    S S     +G+  +L 
Sbjct: 567 YQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLS 626

Query: 530 HSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQES 589
            +   SGS  S      + +  +   S + PH      S   GP  S  G  S +G  +S
Sbjct: 627 SAVSASGSTSS------QGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVG--SPVGSNQS 678

Query: 590 RSGQSSGYGQHGSS-----SGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSS 644
           RSG  S     GS       G  S    H + S QS    + G  +G           + 
Sbjct: 679 RSGPISPASIPGSQMPPQPPGSQSESSSHPALS-QSPMPQERGFMAGTQR--------NP 729

Query: 645 QSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWS---SSNGPHGSVS------ 695
           Q ++YG Q +G   SP     G      SS+ Q  S   +    S  GP G+ S      
Sbjct: 730 QMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYS 789

Query: 696 --GQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHG--------SRSGQSSRSEQHGSS 745
               +S  G   G G S+    HG G S   G    G        +R    + S    SS
Sbjct: 790 GVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSS 849

Query: 746 SGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSS 803
            G+S   G  G G    + + +    +        + + S   S  G + SG   SSS
Sbjct: 850 PGMSQQ-GGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSS 906



 Score = 82.0 bits (201), Expect = 8e-15
 Identities = 199/845 (23%), Positives = 286/845 (33%), Gaps = 86/845 (10%)

Query: 179 YGEQNSDSHQSSGR-GQCGS--GSGQSPNYGQHGSGSGQSSS---------NDTHGSGSG 226
           YG     S    GR G C    G  QSP  G   S S  ++          N   G  + 
Sbjct: 176 YGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNS 235

Query: 227 QSSGFSQHKSSSGQSSGYSQHGSGSGHS-SGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ 285
           Q + +  + S  G   G    G G G S  G G  G+ +G +  G    +++ ++++ G 
Sbjct: 236 QCNHYPGY-SRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGG 294

Query: 286 HGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQT 345
            G G     G    G G   SP       G G     G  G+ S    + G    G  + 
Sbjct: 295 GGGG---GYGGSSAGYGVLSSPRQ----QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRF 347

Query: 346 SGFGQHESGSGQSSGY---SKHGSGSGHSSSQGQHGSTSGQASSSGQ-HGSSSRQSSSYG 401
           +G  QH SG+  +      S       +  S  ++ S S       Q    ++   ++ G
Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407

Query: 402 QHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSS--GPYVSGS 459
             ++A+    G+   +  +  SP        S  + S G  G   GRS  S   P V   
Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467

Query: 460 GYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHG-SRSGQSSRGERQGSSAGSS---- 514
               G G +  S    S     GS       +G  G  R     +G   G+ AG      
Sbjct: 468 PQLYGMGSNPHSQPQQSSPYPGGS-------YGPPGPQRYPIGIQGRTPGAMAGMQYPQQ 520

Query: 515 ---SSYGQHGSGSRQSLGHSRHGSGSGQSPS--------PSRGRHESGSRQSSSYGPHGY 563
                YGQ G       G   + S   Q P         PS+ +     +Q  S    GY
Sbjct: 521 QMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMS--QEGY 578

Query: 564 GSGRSSSRGPYESGSGHSSGLG--HQESRSGQSSGYGQ-HGSSSGHSSTHGQHGSTSGQS 620
           G   + S+ P   G  +   L    QE  S      G      +G  +T     S SG +
Sbjct: 579 G---TRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGST 635

Query: 621 SSCGQHG--ATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFG-HSSSYGQ 677
           SS G     A S  S     H S           GS  G + SR    S      S    
Sbjct: 636 SSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPP 695

Query: 678 HGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSS 737
              GS   SS+ P  S S      G  +G+ ++   +Q+G   +  S    H S  GQ  
Sbjct: 696 QPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPS-MSPHPSPGGQMH 754

Query: 738 RSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSG-HSPSRVRHGSSSGHSSSHGQHGS 796
                   S  S +YG   S       + R  + SG  S S    G   G S+++  HG 
Sbjct: 755 AGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQ 814

Query: 797 GTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQ 856
           G   S  CG    G   ++G  Q+    G   S   S+ G  S QG  G      +    
Sbjct: 815 GP--SQPCGAVPLGRMPSAGM-QNRPFPGNMSSMTPSSPG-MSQQGGPGMGPPMPTV--- 867

Query: 857 HDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSP-SYGRHGSGSGR 915
             +   Q ++    ++A++ A  R       G  PG  Q G  +  SP S   + S S  
Sbjct: 868 --NRKAQEAAAAVMQAAANSAQSR------QGSFPGMNQSGLMASSSPYSQPMNNSSSLM 919

Query: 916 SSSSGRHG------SGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 969
           ++ +  +       + S  S G     S G+S          G      Q  S+S +SS 
Sbjct: 920 NTQAPPYSMAPAMVNSSAASVGLADMMSPGESK-LPLPLKADGKEEGTPQPESKSKKSSS 978

Query: 970 SEQHG 974
           S   G
Sbjct: 979 STTTG 983



 Score = 79.7 bits (195), Expect = 4e-14
 Identities = 169/744 (22%), Positives = 246/744 (33%), Gaps = 105/744 (14%)

Query: 2135 QHGSRSGQSSRGE----------RHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPS 2184
            QHG     ++ G+          + G    +  + G+   G  +  G G  G+       
Sbjct: 100  QHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAV 159

Query: 2185 RGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS 2244
             G  G  +     +  +GS +  S   G    R+G    F QH    G  S     G G 
Sbjct: 160  PGGGGGPAAVPEFNNYYGSAAPASGGPG---GRAG--PCFDQH---GGQQSP----GMGM 207

Query: 2245 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGR 2304
             H  S    G+          + S  G  +S   H  G S+  + G  G G G     G 
Sbjct: 208  MHSASAAAAGAPGSMDPL---QNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGG 264

Query: 2305 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHS 2364
             G G G     G  G+G+G  +++    + +    G G          GY    +G G  
Sbjct: 265  GGGGGGA----GAGGAGAGAVAAAAAAAAAAAGGGGGG----------GYGGSSAGYGVL 310

Query: 2365 SSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ-------SP 2417
            SS  Q G        G   G++S S ++ G    G ++  G  QH SG+         SP
Sbjct: 311  SSPRQQGGGMMMGPGGG--GAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSP 368

Query: 2418 SPSRGRHGSGSGQSSSYS----PYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQ---- 2469
            SP    +G    + SS S    P       +++ G    G   ++G+G  +    Q    
Sbjct: 369  SPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAA 428

Query: 2470 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSC---------------GQHGASSGQSSSH-- 2512
            S  +      S  + + G  G T G+S                  G +  S  Q SS   
Sbjct: 429  SPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYP 488

Query: 2513 -GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHG------SGSGRSSSSG 2565
             G +G    Q    G QG   G   G   +    +  P YG+ G       G     S  
Sbjct: 489  GGSYGPPGPQRYPIGIQGRTPGAMAG--MQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQ 546

Query: 2566 QHGSGLGESSGFGHHESSSG----QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGS 2621
                 L   + +   +S       Q  S   +G+ S      G+         + ER  S
Sbjct: 547  PQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSS 606

Query: 2622 SSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSR 2681
                S       +G+  +       SGS  S     + +     S    H S    S   
Sbjct: 607  LPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPA----QSPFSPHASPHLSSIPG 662

Query: 2682 GPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS----GQSSTFDQEG 2737
            GP  S +G  S  G ++S SG  S  S  GS         Q  S+S     QS    + G
Sbjct: 663  GPSPSPVG--SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG 720

Query: 2738 SSTG-----QSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGS 2792
               G     Q + YG + +G S S     H +  GQ  +       S  S +YG   S  
Sbjct: 721  FMAGTQRNPQMAQYGPQQTGPSMSP----HPSPGGQMHAGISSFQQSNSSGTYGPQMSQY 776

Query: 2793 GQSSGYSQHGSGSGQDGYSYCKGG 2816
            G    YS+  + SG    SY   G
Sbjct: 777  GPQGNYSRPPAYSGVPSASYSGPG 800



 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 101/461 (21%), Positives = 151/461 (32%), Gaps = 34/461 (7%)

Query: 2219 GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQ 2278
            G +     H+    H  A+  H     H      H +   Q + F Q+     Q     Q
Sbjct: 15   GEAPAAPPHQQHHHHHHAHHHHH----HAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQ 70

Query: 2279 HGSGS-SQSSSYGQQGSGSGQ-SPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 2336
                  S ++S G  G G+ Q  P   +   G    S+ G      G    S + G    
Sbjct: 71   QQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS-KPGDEDD 129

Query: 2337 QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQH 2396
                 G      ++  G    G+     +     G  +        +GS++ +S      
Sbjct: 130  APPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG----- 184

Query: 2397 GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGH 2456
            G G R      QHG   GQ  SP  G   S S  ++  +P       +S  G   S   H
Sbjct: 185  GPGGRAGPCFDQHG---GQQ-SPGMGMMHSASAAAAG-APGSMDPLQNSHEGYPNSQCNH 239

Query: 2457 SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHG 2516
              G     +  G   G G  G S G     G     +G  +      A++  +   G  G
Sbjct: 240  YPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGG 299

Query: 2517 SGSSQSSGYG------RQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSG 2570
             G S S+GYG      +QG G    PG G  G+ S    + G    G  R +   QH SG
Sbjct: 300  YGGS-SAGYGVLSSPRQQGGGMMMGPGGG--GAASLSKAAAGSAAGGFQRFAGQNQHPSG 356

Query: 2571 LGE------SSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSG 2624
                     +S      S  G    YS   +     S      + +G ++ G++  +  G
Sbjct: 357  ATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMG 416

Query: 2625 SSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHS 2665
                 G   + +  +    +Q S    SP  G  G  +G S
Sbjct: 417  LGKDMGAQYAAASPAWAAAQQRSHPAMSP--GTPGPTMGRS 455



 Score = 58.9 bits (141), Expect = 7e-08
 Identities = 198/887 (22%), Positives = 292/887 (32%), Gaps = 126/887 (14%)

Query: 248  GSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGS------ 301
            G+ +  SS     GS S Q  +      S+ + S +  H S    S+  G   S      
Sbjct: 620  GTEATLSSAVSASGSTSSQGDQ------SNPAQSPFSPHASPHLSSIPGGPSPSPVGSPV 673

Query: 302  GSRQSPSH-VRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSG 360
            GS QS S  +   S  G        GS S  S      +S   Q  GF      + Q + 
Sbjct: 674  GSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQ 733

Query: 361  YSKHGSG---SGHSSSQGQ-HGSTSG--QASSSGQHGSSSRQSSSYGQHESASRHSSGRG 414
            Y    +G   S H S  GQ H   S   Q++SSG +G    Q S YG   + SR  +  G
Sbjct: 734  YGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGP---QMSQYGPQGNYSRPPAYSG 790

Query: 415  QHSSG-SGQSPGHGQRGSGS--GQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESS 471
              S+  SG  PG G   +    GQ PS        GR  S+G  +    +    G+  S 
Sbjct: 791  VPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAG--MQNRPFP---GNMSSM 845

Query: 472  SEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHS 531
            +  S G +Q G            G      +   +   +A +      + + SRQ     
Sbjct: 846  TPSSPGMSQQGGP----------GMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPG 895

Query: 532  RHGSGSGQSPSP-SRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESR 590
             + SG   S SP S+  + S S  ++   P+       +S          ++ +G  +  
Sbjct: 896  MNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSS---------AASVGLADMM 946

Query: 591  SGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRY- 649
            S   S       + G      Q  S S +SSS    G    +    G          RY 
Sbjct: 947  SPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYL 1006

Query: 650  ---GQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSS-GFGHKS 705
                ++GS     P+ G+   D        +   G    + N     ++   + G    +
Sbjct: 1007 TFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSA 1066

Query: 706  GSGQSSGYSQH--------GSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGS 757
             S     Y Q+          G          G    Q        ++SG        G 
Sbjct: 1067 ASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSG-----SLQGP 1121

Query: 758  GSHQSSGHGRQGSGSGH----SPSRVRHGSSS----GHSSSHGQHGSGTSCSSSC----- 804
             + QS+G        G     +P+   HG  +    G SS+   H   +  S S      
Sbjct: 1122 QTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRN 1181

Query: 805  -----GHYESGSGQASGFGQHESGSGQ----GYSQHGSASGHFSSQGRHGSTS-----GQ 850
                   Y+ G       G+      +    G  +   +S  F +QG+  ++S      Q
Sbjct: 1182 SMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQ 1241

Query: 851  SSSSGQHDSSSGQSSS--YGQHESASHHASGRGRHGSG--SGQSPGHGQRGSGSGQSPSY 906
            S S    +   GQ     YG      H   G+   G G  SGQ P  G +     Q P+Y
Sbjct: 1242 SPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNY 1301

Query: 907  GRHGSGSGRSSSSGRHGSGSGQSSG--FGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRS 964
             RH          G +G  + +  G  +  + SS Q   Y Q+G            GS S
Sbjct: 1302 KRH--------MDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYG------------GSYS 1341

Query: 965  GQSSRSEQHGSSSGSSSSYGQHGSGSRQSLG-HGQHGSGSGQSPSPSRGRHGSGSGQSSS 1023
            G   R  Q G      S     G G  Q+ G   Q   G  QS S    +    + ++  
Sbjct: 1342 GPDRRPIQ-GQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDM 1400

Query: 1024 YGPY--RSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGS 1068
              PY  R G G  +   PY  G   +  +   + R    S +  H S
Sbjct: 1401 PYPYQNRQGPGGPTQAPPY-PGMNRTDDMMVPDQRINHESQWPSHVS 1446



 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 84/399 (21%), Positives = 128/399 (32%), Gaps = 67/399 (16%)

Query: 2469 QSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 2528
            Q   +  H     H + H  H     Q  +  Q      Q     Q       S+     
Sbjct: 24   QQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLG 83

Query: 2529 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH---GSGLGESSGFGHHESSSG 2585
            G+G G +P  G       + P +G    G+  S++ GQ    G  L    G         
Sbjct: 84   GAGGG-APQPGP----DMEQPQHG----GAKDSAAGGQADPPGPPLLSKPG-----DEDD 129

Query: 2586 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHG-R 2644
                  +   G     G G  G++    +     G  +        +GS +  S G G R
Sbjct: 130  APPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGR 189

Query: 2645 QGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHS 2704
             G    Q   +   G G+ HS+S     + +G   S  P ++     S  G   S   H 
Sbjct: 190  AGPCFDQHGGQQSPGMGMMHSAS----AAAAGAPGSMDPLQN-----SHEGYPNSQCNHY 240

Query: 2705 SAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGA 2764
              YS+ G+G G        G   G        G  +G     G  G+G + +       A
Sbjct: 241  PGYSRPGAGGG--------GGGGGGG------GGGSGGGGGGGGAGAGGAGAGAVAAAAA 286

Query: 2765 GSGQSLSHGRHGSGSGQSSSYG------------QHGSGSGQSSGYSQHGSGSGQDGYSY 2812
             +  +   G  G   G S+ YG              G G G ++  S+  +GS   G+  
Sbjct: 287  AAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQR 346

Query: 2813 CKGGSNHDGGSS--------------GSYFLSFPSSTSP 2837
              G + H  G++               SY  S+P  +SP
Sbjct: 347  FAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSP 385



 Score = 48.5 bits (114), Expect = 9e-05
 Identities = 83/328 (25%), Positives = 112/328 (34%), Gaps = 59/328 (17%)

Query: 1450 SSSYGQHGSGSRQSLGHGQHGSGSG--QSPSPSRGRHGSGS----GQSSSYSPYGSGSGW 1503
            ++S    G  + QS G        G  + P+P+   HG  +    G+SS+ S +   S  
Sbjct: 1113 ANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDV 1172

Query: 1504 SSS----------RGPYESGSSHSSGLGHR--ESRSGQSSGYGQHGSSSGHSSTHGQHGS 1551
            S S            PY+ G S    +G    E       G  +   SS    T GQ  +
Sbjct: 1173 SDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPN 1232

Query: 1552 TS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ----GSGSGQSPGHGQRG 1602
            +S      QS S        GQ        S   +   YG+Q    G  SGQ P  G + 
Sbjct: 1233 SSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQP 1292

Query: 1603 SGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 1662
                Q P+Y RH  G     +    G          + + SS Q   Y+Q+G        
Sbjct: 1293 GLYPQQPNYKRHMDGMYGPPAKRHEGD-------MYNMQYSSQQQEMYNQYG-------- 1337

Query: 1663 YGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL 1722
                GS SG   R    G      SR    G G  Q+ G   Q             G  L
Sbjct: 1338 ----GSYSGPDRR-PIQGQYPYPYSRERMQGPGQIQTHGIPPQ-----------MMGGPL 1381

Query: 1723 GHSSSHG-QHGSGSGRSSSRGPYESRSG 1749
              SSS G Q    + R+    PY++R G
Sbjct: 1382 QSSSSEGPQQNMWAARNDMPYPYQNRQG 1409



 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 81/328 (24%), Positives = 111/328 (33%), Gaps = 59/328 (17%)

Query: 1920 SSSYGQHGSGSRQSLGHGQHGSGSG--QSPSPSRGRHGSGS----GQSSSYGPYGSGSGW 1973
            ++S    G  + QS G        G  + P+P+   HG  +    G+SS+   +   S  
Sbjct: 1113 ANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDV 1172

Query: 1974 SSS----------RGPYESGSGHSSGLGHR--ESRSGQSSGYGQHGSSSGHSSTHGQHGS 2021
            S S            PY+ G      +G    E       G  +   SS    T GQ  +
Sbjct: 1173 SDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPN 1232

Query: 2022 AS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ----GSGSGQSPGHGQRG 2072
            +S      QS S        GQ        S   +   YG+Q    G  SGQ P  G + 
Sbjct: 1233 SSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQP 1292

Query: 2073 SGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHH-ESSSGQSSSYSQHGSGSGHSS 2131
                Q P+Y RH          G +GP      G  ++ + SS Q   Y+Q+G       
Sbjct: 1293 GLYPQQPNYKRH--------MDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYG------- 1337

Query: 2132 GYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSG 2191
                 GS SG   R    G      SR    G G  Q+ G   Q  G          G  
Sbjct: 1338 -----GSYSGPDRR-PIQGQYPYPYSRERMQGPGQIQTHGIPPQMMG----------GPL 1381

Query: 2192 SGHSSSHGQHGSGSGRSSSRGPYESRSG 2219
               SS   Q    + R+    PY++R G
Sbjct: 1382 QSSSSEGPQQNMWAARNDMPYPYQNRQG 1409



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 81/328 (24%), Positives = 110/328 (33%), Gaps = 59/328 (17%)

Query: 2390 SSSYGQHGSGSRQSLGHGQHGSGSG--QSPSPSRGRHGSGS----GQSSSYSPYGSGSGW 2443
            ++S    G  + QS G        G  + P+P+   HG  +    G+SS+ S +   S  
Sbjct: 1113 ANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDV 1172

Query: 2444 SSS----------RGPYESGSGHSSGLGHR--ESRSGQSSGYGQHGSSSGHSSTHGQHGS 2491
            S S            PY+ G      +G    E       G  +   SS    T GQ  +
Sbjct: 1173 SDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPN 1232

Query: 2492 TS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ----GSGSGQSPGHGQRG 2542
            +S      QS S        GQ        S   +   YG+Q    G  SGQ P  G + 
Sbjct: 1233 SSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQP 1292

Query: 2543 SGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 2602
                Q P+Y RH  G     +    G          + + SS Q   Y+Q+G        
Sbjct: 1293 GLYPQQPNYKRHMDGMYGPPAKRHEGD-------MYNMQYSSQQQEMYNQYG-------- 1337

Query: 2603 YGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL 2662
                GS SG   R    G      S     G G  Q+ G   Q             G  L
Sbjct: 1338 ----GSYSGPDRR-PIQGQYPYPYSRERMQGPGQIQTHGIPPQ-----------MMGGPL 1381

Query: 2663 GHSSSHG-QHGSGSGRSSSRGPYESRLG 2689
              SSS G Q    + R+    PY++R G
Sbjct: 1382 QSSSSEGPQQNMWAARNDMPYPYQNRQG 1409



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 82/330 (24%), Positives = 109/330 (33%), Gaps = 47/330 (14%)

Query: 962  SRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQS 1021
            S S Q  ++ Q   S+  +   G     +  S  HGQ     G   S +   H   S  S
Sbjct: 1115 SGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQG-GRSSTISVHDPFSDVS 1173

Query: 1022 SSYGPYRSGSGWSSSRGPYESGSGHSSGLGHR--ESRSGQSSGYGQHGSSSGHSSTHGQH 1079
             S  P R+     +   PY+ G      +G    E       G  +   SS    T GQ 
Sbjct: 1174 DSSFPKRNSM---TPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQM 1230

Query: 1080 GSTS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ----GSGSGQSPGHGQ 1130
             ++S      QS S        GQ        S   +   YG+Q    G  SGQ P  G 
Sbjct: 1231 PNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGH 1290

Query: 1131 RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 1190
            +     Q P+Y RH  G     +    G          + + SS Q   Y+Q+G      
Sbjct: 1291 QPGLYPQQPNYKRHMDGMYGPPAKRHEGD-------MYNMQYSSQQQEMYNQYG------ 1337

Query: 1191 SGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGS 1250
                  GS SG   R    G      S     G G  Q+ G   Q             G 
Sbjct: 1338 ------GSYSGPDRR-PIQGQYPYPYSRERMQGPGQIQTHGIPPQ-----------MMGG 1379

Query: 1251 GLGHSSSHG-QHGSGSGRSSSRGPYESRSG 1279
             L  SSS G Q    + R+    PY++R G
Sbjct: 1380 PLQSSSSEGPQQNMWAARNDMPYPYQNRQG 1409


>gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo
            sapiens]
          Length = 1726

 Score =  105 bits (261), Expect = 8e-22
 Identities = 200/965 (20%), Positives = 333/965 (34%), Gaps = 102/965 (10%)

Query: 1512 SGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTS------------GQSSSC 1559
            +GS+  +  GH +  +G +   G    S  + S  G  G+ S            G SS  
Sbjct: 3    TGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGL 62

Query: 1560 GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS-GS 1618
                 S G        G G SQ+  +G   S +G +       + +   P  G  G+  +
Sbjct: 63   AHCSVSGGDGKMDTMIGDGRSQNC-WGASNSNAGINLNLNPNANPAAW-PVLGHEGTVAT 120

Query: 1619 GRSSSSGQHGSGLGESSG--FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 1676
            G  SS     S +G++ G   G+   + G   +     S    +S   Q+ S S Q    
Sbjct: 121  GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTS-TSQNVSFSAQPQNL 179

Query: 1677 ERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL--GHSSSHGQHGSG 1734
               G ++ +      +   + Q++G    G   G       H  GL   + SS  Q   G
Sbjct: 180  NTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGG 239

Query: 1735 SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD 1794
            S    S          +SV+G         ++ S    G+G   +       +G SS   
Sbjct: 240  SAEGIS----------NSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQ 289

Query: 1795 QEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGW 1854
            +EGS      S    G G          G GSG +     H    GH S    +G    W
Sbjct: 290  KEGSGGNAWDSGPPAGPGIL------AWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEW 343

Query: 1855 SSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHG----SGSGHSSSYEQHGSRSGQSSRG 1910
                 +H +      G     S+ W+S   T        G  H +S+ +  S    +S G
Sbjct: 344  GKPPNQHSNSDINGKG-----STGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEG 398

Query: 1911 EQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS---PSRGRHGSGSGQSSSYGPY 1967
               GS + +  S G+ G+G  +    G    G  Q P      R    +G GQ+    P 
Sbjct: 399  SSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQT----PV 454

Query: 1968 GSGSGWSSSRGP-YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQS 2026
               + W     P  E  + + +      +    +SG    GS    ++T    G  +   
Sbjct: 455  KQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPP 514

Query: 2027 SSCGQHGASSGQSSSHGQHGSGS---SQSSGYGRQGSGSGQSPGHGQRGSGSRQ--SPSY 2081
            ++     A++G   S+ +  SG      S       + +    GH   G+ +++  SP++
Sbjct: 515  AAV---PANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTW 571

Query: 2082 GRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSG 2141
            G       +    GQ       + G    +S    SS     G G  + SG+    +RSG
Sbjct: 572  GEPPKPKSQHWGDGQRSNPAWSAGGGDWADS----SSVLGHLGDGKKNGSGWDADSNRSG 627

Query: 2142 QSSRGERHGSSSG---SSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSH 2198
                      +SG   S++     G+   ++   G Q + +  S  +  + S  G ++S 
Sbjct: 628  SGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWA--SKPQDNNVSNWGGAASV 685

Query: 2199 GQHGSG--------SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ 2250
             Q G+G          + SS           S+  + E   G +SA+    + +    + 
Sbjct: 686  KQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDG-TSAWGDPSNYNNKTVNM 744

Query: 2251 GQHGSTSGQSSTFDQEGSSTGQSSSHGQH----------GSGSSQSSSYGQQGSGSGQSP 2300
                +   QSST     ++T  ++S+  H          G+  ++S   G   SG G+ P
Sbjct: 745  WDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGWGEMP 804

Query: 2301 --------SRGRHGSGS----GHSSSYGQ-HGSGSGWSSSSGRHGSGSGQSSGFGHHESS 2347
                    S G   S S      ++++G+   SGSGW           G++       + 
Sbjct: 805  NVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASAL 864

Query: 2348 SWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHG 2407
               +S   Q G GSG             +      + +S  S+SS    G+  ++ L  G
Sbjct: 865  CKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKG 924

Query: 2408 QHGSG 2412
               SG
Sbjct: 925  MKTSG 929



 Score = 88.6 bits (218), Expect = 8e-17
 Identities = 203/963 (21%), Positives = 345/963 (35%), Gaps = 102/963 (10%)

Query: 576  SGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSS 635
            +GS   +  GH +  +G +   G    S  + S  G  G+ S   S+    G  +G SS 
Sbjct: 3    TGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSN-GSAARVWGVATGSSSG 61

Query: 636  HGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVS 695
                             G G  Q+   G   S+ G + +   + + + W    G  G+V+
Sbjct: 62   LAHCSVSGGDGKMDTMIGDGRSQN-CWGASNSNAGINLNLNPNANPAAWPVL-GHEGTVA 119

Query: 696  --GQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSY- 752
                SS     S  GQ+ G +Q+G+ +     +   G+   Q S   Q  +S  +S S  
Sbjct: 120  TGNPSSICSPVSAIGQNMG-NQNGNPTGTLGAW---GNLLPQESTEPQTSTSQNVSFSAQ 175

Query: 753  -------GQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCG 805
                   G + +    SS +      +   P+    G + G  +    H  G   ++   
Sbjct: 176  PQNLNTDGPNNTNPMNSSPNPINAMQTNGLPN---WGMAVGMGAIIPPHLQGLPGANGSS 232

Query: 806  HYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSS 865
              +   G A G      G   G    G+++  FS QG +G T   + S+ Q+ SSS    
Sbjct: 233  VSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFS-QG-NGDTVNSALSAKQNGSSS---- 286

Query: 866  SYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSG---RSSSSGRH 922
                  +     SG     SG    PG    G GSG +     H    G   RS+S+G +
Sbjct: 287  ------AVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVN 340

Query: 923  GS-----GSGQSSGFGHKSSSG-QSSGYTQHG----SGSGHSSSYEQHGSRSGQSSRSEQ 972
            G          +S    K S+G +S   T        G  H +S+ +  S    +S    
Sbjct: 341  GEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSS 400

Query: 973  HGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS---PSRGRHGSGSGQSSSYGPYRS 1029
             GS + +  S G+ G+G  +    G    G  Q P      R    +G GQ+    P + 
Sbjct: 401  DGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQT----PVKQ 456

Query: 1030 GSGWSSSRGP-YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSS 1088
             + W     P  E  + + +      +    +SG    GS    ++T    G  +   ++
Sbjct: 457  NTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAA 516

Query: 1089 CGQHGASSGQSSSHGQHGSGS---SQSSGYGRQGSGSGQSPGHGQRGSGSRQ--SPSYGR 1143
                 A++G   S+ +  SG      S       + +    GH   G+ +++  SP++G 
Sbjct: 517  V---PANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGE 573

Query: 1144 HGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQS 1203
                  +    GQ  +    + G    +S    SS     G G  + SG+    +RSG  
Sbjct: 574  PPKPKSQHWGDGQRSNPAWSAGGGDWADS----SSVLGHLGDGKKNGSGWDADSNRSGSG 629

Query: 1204 SRGERHGSSSG---SSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQ 1260
                    +SG   S++     G+   ++   G Q + +  S  +  + S  G ++S  Q
Sbjct: 630  WNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWA--SKPQDNNVSNWGGAASVKQ 687

Query: 1261 HGSG--------SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ 1312
             G+G          + SS           S+  + E   G +SA+    + +    +   
Sbjct: 688  TGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDG-TSAWGDPSNYNNKTVNMWD 746

Query: 1313 HGSTSGQSS-TFDQEGSSTGQSSSYGHR---------GSGSSQSSGYGRHGAGSGQSP-- 1360
              +   QSS T +   ++T  +S+  HR         G+  ++S   G   +G G+ P  
Sbjct: 747  RNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGWGEMPNV 806

Query: 1361 ------SRGRHGSGS----GHSSSYGQ-HGSGSGWSSSSGRHGSGSGQSSGFGHHESSSW 1409
                  S G   S S      ++++G+   SGSGW           G++       +   
Sbjct: 807  HSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCK 866

Query: 1410 QSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQH 1469
             +S   Q G GSG             +      + +S  S+SS    G+  ++ L  G  
Sbjct: 867  PASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKGMK 926

Query: 1470 GSG 1472
             SG
Sbjct: 927  TSG 929



 Score = 85.9 bits (211), Expect = 5e-16
 Identities = 157/725 (21%), Positives = 264/725 (36%), Gaps = 108/725 (14%)

Query: 482  GSGSGHSSGH-----GQHG-------SRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLG 529
            GS  G+ +GH     G +G       S S QS+ G    +S GS++      +GS   L 
Sbjct: 4    GSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLA 63

Query: 530  HSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES------------- 576
            H     G G+  +          R  + +G     +G + +  P  +             
Sbjct: 64   HCSVSGGDGKMDTMI-----GDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTV 118

Query: 577  GSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQ---HGSTSGQSSSCGQHGATSGQS 633
             +G+ S +    S  GQ+ G  Q+G+ +G     G      ST  Q+S+  Q+ + S Q 
Sbjct: 119  ATGNPSSICSPVSAIGQNMG-NQNGNPTGTLGAWGNLLPQESTEPQTST-SQNVSFSAQP 176

Query: 634  SSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGS 693
             +    G  ++           + Q+      G   G  +    H  G       G +GS
Sbjct: 177  QNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQG-----LPGANGS 231

Query: 694  VSGQSSGFGHKSGSGQSSGYS--QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSS 751
               Q SG   +  S    G S     +G+S+S   + +G     +  ++Q+GSSS +   
Sbjct: 232  SVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQK- 290

Query: 752  YGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGH--YES 809
                     + SG     SG    P  +  G  SG+      +G G   S + GH    +
Sbjct: 291  ---------EGSGGNAWDSGPPAGPGILAWGRGSGN------NGVGNIHSGAWGHPSRST 335

Query: 810  GSGQASGFG----QHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSS 865
             +G    +G    QH +    G    G  S   +SQ       G+  +S    +SSG ++
Sbjct: 336  SNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTA 395

Query: 866  SYGQHESASHHASG-RGRHGSGSGQ-------SPGHGQ-----------RGSGSGQSP-- 904
            S G  + + +H  G  GR G+G G+         GH Q             +G GQ+P  
Sbjct: 396  SEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVK 455

Query: 905  -SYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSR 963
             +       S RS     +G+ +   +     +S G++ G   + + +   S +      
Sbjct: 456  QNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPA 515

Query: 964  S-------GQSSRSEQHGSSS-GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1015
            +       G S+     G    G S S     + +    GH   G+ + +  SP+ G   
Sbjct: 516  AVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPP 575

Query: 1016 SGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG---H 1072
                Q    G  RS   WS+  G +   +  SS LGH        SG+    + SG   +
Sbjct: 576  KPKSQHWGDG-QRSNPAWSAGGGDW---ADSSSVLGHLGDGKKNGSGWDADSNRSGSGWN 631

Query: 1073 SSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQS-----SGYGRQGSGSGQSPG 1127
             +T   +      +++    G + G++   G   + +S+      S +G  G+ S +  G
Sbjct: 632  DTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWG--GAASVKQTG 689

Query: 1128 HGQRG 1132
             G  G
Sbjct: 690  TGWIG 694



 Score = 85.9 bits (211), Expect = 5e-16
 Identities = 160/714 (22%), Positives = 262/714 (36%), Gaps = 71/714 (9%)

Query: 2112 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSG 2171
            S+ G  + +++  +G+  ++G     S S QS+ G    +S+GS++R     +GS     
Sbjct: 5    SAQGNFTGHTKKTNGNNGTNG-ALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLA 63

Query: 2172 HGRQGSGSGHSPSRGRHGSGSGHSSS-HGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG 2230
            H     G G   +      G G S +  G   S +G + +  P  + +    +  +    
Sbjct: 64   HCSVSGGDGKMDTM----IGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVA 119

Query: 2231 SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ--EGSSTGQSSSHGQHGSGSSQSSS 2288
            +G+ S+     S  G      Q+G+ +G    +       ST   +S  Q+ S S+Q  +
Sbjct: 120  TGNPSSICSPVSAIGQNMGN-QNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQN 178

Query: 2289 YGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSS 2348
                G  +    +   +   +  ++     G   G  +    H  G   ++G     SS 
Sbjct: 179  LNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANG-----SSV 233

Query: 2349 WQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQ 2408
             Q SG    GS  G S+S    G   G  + G    S+SG S     +G     +L   Q
Sbjct: 234  SQVSG----GSAEGISNSV--WGLSPGNPATGN---SNSGFSQG---NGDTVNSALSAKQ 281

Query: 2409 HGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGS-GWSSSRGPYESGSGHSSGLGH--RES 2465
            +GS S         + GSG     S  P G G   W    G    G+ HS   GH  R +
Sbjct: 282  NGSSSAVQ------KEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRST 335

Query: 2466 RSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGY 2525
             +G +  +G+  +   +S  +G+ GST  +S S      +      H    + ++ S   
Sbjct: 336  SNGVNGEWGKPPNQHSNSDINGK-GSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTT 394

Query: 2526 GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 2585
              +GS  G         SG+    S GR G+G GR    G    G        H +    
Sbjct: 395  ASEGSSDG---------SGNHNEGSTGREGTGEGRRRDKGIIDQG--------HIQLPRN 437

Query: 2586 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQ 2645
                     +G G +           +S R ER   +   +      G  + Q+S  G +
Sbjct: 438  DLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEA-----WGCAATQASNSGGK 492

Query: 2646 GSGSGQSPSRGRHGSGLGHSSSHG-QHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHS 2704
              GS  + +     SG  ++        +G G S+++ P         V+G   S +  S
Sbjct: 493  NDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAP-----SGPGVWGDSISSTAVS 547

Query: 2705 SAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGA 2764
            +A +   + SGH  S     +   +S T+ +      Q    G R S  + S+G G   A
Sbjct: 548  TAAA---AKSGHAWSGA--ANQEDKSPTWGEPPKPKSQHWGDGQR-SNPAWSAG-GGDWA 600

Query: 2765 GSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSN 2818
             S   L H   G  +G       + SGSG +       SG G    +    G+N
Sbjct: 601  DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTN 654



 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 199/978 (20%), Positives = 365/978 (37%), Gaps = 148/978 (15%)

Query: 236  SSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLG 295
            S+ G  +G+++  +G+  ++G     S S QS+ G    +S+GS++      +GS   L 
Sbjct: 5    SAQGNFTGHTKKTNGNNGTNG-ALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLA 63

Query: 296  HGRQGSGSRQSPSHVRHG----------SGSGHSSSHGQHGSGSSYSYSRGHYESGSGQT 345
            H     G  +  + +  G          S +G + +   + + +++          +G  
Sbjct: 64   HCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNP 123

Query: 346  SGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHES 405
            S      S  GQ+ G +++G+ +G   + G  G+   Q S+  Q  +S+ Q+ S+     
Sbjct: 124  SSICSPVSAIGQNMG-NQNGNPTG---TLGAWGNLLPQESTEPQ--TSTSQNVSFSAQPQ 177

Query: 406  ASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGF 465
                      +   S  +P +  + +G          G   G  +   P++ G   ++G 
Sbjct: 178  NLNTDGPNNTNPMNSSPNPINAMQTNG------LPNWGMAVGMGAIIPPHLQGLPGANG- 230

Query: 466  GHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSR 525
                S S+ S G  +  S S      G   + +  S   +  G +  S+ S  Q+GS S 
Sbjct: 231  ---SSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSS- 286

Query: 526  QSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLG 585
                  + GSG            +SG          G GSG +        G+ HS   G
Sbjct: 287  ---AVQKEGSGG--------NAWDSGPPAGPGILAWGRGSGNNG------VGNIHSGAWG 329

Query: 586  H--QESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC----------GQH------G 627
            H  + + +G +  +G+  +   +S  +G+ GST  +S S           G+H       
Sbjct: 330  HPSRSTSNGVNGEWGKPPNQHSNSDINGK-GSTGWESPSVTSQNPTVQPGGEHMNSWAKA 388

Query: 628  ATSGQSSSHG-QHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGH-----SSSYGQHGSG 681
            A+SG ++S G   GSG+      G++G+G G+   +G    D GH     +    +  S 
Sbjct: 389  ASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGI--IDQGHIQLPRNDLDPRVLSN 446

Query: 682  SGWSSSNGPHGSV-SGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSE 740
            +GW  +     +    + S    +     +  +    + +S+S G +  GS    ++ S 
Sbjct: 447  TGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGG-KNDGSIMNSTNTSS 505

Query: 741  QHG----SSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGS 796
              G      + + ++ G   S +   SG G  G     +       + SGH+ S   +  
Sbjct: 506  VSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQE 565

Query: 797  GTSCSSSCGHYESGSGQASGFGQHE----SGSGQGYSQHGSASGHFSSQGRHGS---TSG 849
                S + G       Q  G GQ      S  G  ++   S  GH     ++GS      
Sbjct: 566  DK--SPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADS 623

Query: 850  QSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQS--PGHGQRGSGSGQSPSYG 907
              S SG +D++   +S +G      +  + +   G+  G++  PG  Q  +   Q  +  
Sbjct: 624  NRSGSGWNDTTRSGNSGWG------NSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVS 677

Query: 908  R-HGSGSGRSSSSGRHG-------SGSGQSSGFGHKSSSG------QSSGYTQHGSGSGH 953
               G+ S + + +G  G         S +++G+   S            G +  G  S +
Sbjct: 678  NWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNY 737

Query: 954  SSSYEQHGSRSG---QSSRSEQHGSSSGSSSSYGQH----------GSGSRQSLGHGQHG 1000
            ++       R+    QSS +    +++ +++S   H          G+   +S   G   
Sbjct: 738  NNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVS 797

Query: 1001 SGSGQSP---SPSRGRHGSGSGQS-------SSYG-PYRSGSGWSS--SRGPYESGSG-- 1045
            SG G+ P   S +    G  S  S       +++G P  SGSGW    +  P   G    
Sbjct: 798  SGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGA 857

Query: 1046 --HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQ--------HGSTSGQSSSCGQHGAS 1095
               +S L    S+S Q  G+G  G     S++  +        + ++   +SSC   G +
Sbjct: 858  PVAASALCKPASKSMQ-EGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNA 916

Query: 1096 SGQSSSHGQHGSGSSQSS 1113
              +    G   SG    +
Sbjct: 917  PKKGLQKGMKTSGKQDEA 934



 Score = 82.4 bits (202), Expect = 6e-15
 Identities = 213/997 (21%), Positives = 357/997 (35%), Gaps = 128/997 (12%)

Query: 1119 GSGSGQSPGHGQRGSGSR-------QSPSYGRHGSGSGRSSSSGQH----GSGLGESSGF 1167
            GS  G   GH ++ +G+        QSPS  +   G+G ++S+G      G   G SSG 
Sbjct: 4    GSAQGNFTGHTKKTNGNNGTNGALVQSPS-NQSALGAGGANSNGSAARVWGVATGSSSGL 62

Query: 1168 GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSS--SHYGQHGSG 1225
             H   S G     +  G G   +  +G   S +G +     + + +      H G   +G
Sbjct: 63   AHCSVSGGDGKMDTMIGDGRSQNC-WGASNSNAGINLNLNPNANPAAWPVLGHEGTVATG 121

Query: 1226 SRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRG---PYESRSGHSS 1282
            +  S            SP      S +G +  + Q+G+ +G   + G   P ES    +S
Sbjct: 122  NPSSIC----------SPV-----SAIGQNMGN-QNGNPTGTLGAWGNLLPQESTEPQTS 165

Query: 1283 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSY------ 1336
               Q+ S S      +  G  + +  +   +   + Q++     G + G  +        
Sbjct: 166  T-SQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQG 224

Query: 1337 --GHRGSGSSQSSGYGRHGAGS---GQSPSRGRHG-SGSGHSSSYGQHGSGSGWSSSSGR 1390
              G  GS  SQ SG    G  +   G SP     G S SG S   G   + +  +  +G 
Sbjct: 225  LPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGS 284

Query: 1391 HGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSS 1450
              +   + SG    +S      G    G GSG++     H    G  SR   +G +    
Sbjct: 285  SSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWG 344

Query: 1451 SSYGQHGSGSRQSLGH--GQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRG 1508
                QH +      G    +  S + Q+P+   G     S   ++ S   +  G S   G
Sbjct: 345  KPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSG 404

Query: 1509 PYESGSS--HSSGLGHRESRSGQSSGYGQ--HGSSSGHSSTHGQHGSTSGQSSSCGQHGA 1564
             +  GS+    +G G R  +     G+ Q           ++   G T  + ++  +   
Sbjct: 405  NHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEE 464

Query: 1565 S--SGQSSSHGQH--GSGSSQSSGYGRQGSGSGQSPGHGQRGSG-SRQSPSYGRHGSGSG 1619
            S  S + + +G    G  ++Q+S  G +  GS  +  +    SG     P+     +G G
Sbjct: 465  SPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG 524

Query: 1620 RSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERH 1679
             S++    G G+             G S S +   + +   SG+   G+ + Q  +    
Sbjct: 525  DSNNKAPSGPGVW------------GDSISSTAVSTAAAAKSGHAWSGA-ANQEDKSPTW 571

Query: 1680 GSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSS 1739
            G   +  S   QH    ++S+     G G     S     S LGH     ++GSG    S
Sbjct: 572  GEPPKPKS---QHWGDGQRSNPAWSAGGGDWADSS-----SVLGHLGDGKKNGSGWDADS 623

Query: 1740 SRGPYESRSGHSSVFGQHESGSGHS-SAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGS 1798
            +R    S SG +       SG G+S +  +  G+  G     G   + +  S   D   S
Sbjct: 624  NR----SGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWA--SKPQDNNVS 677

Query: 1799 STGQSSSHGQHGSG-------SSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSG 1851
            + G ++S  Q G+G         Q  S    G      PS  R       +S++G   + 
Sbjct: 678  NWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNY 737

Query: 1852 SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGE 1911
            +  + +     +   QSS   +  +++  ++  T H                  ++    
Sbjct: 738  NNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTH----------------RVETPPPH 781

Query: 1912 QHGSSSGSSSSYGQHGSG-SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSG 1970
            Q G+    S   G   SG       H +  +  G+  SPS       +G ++   P  SG
Sbjct: 782  QAGTQLNRSPLLGPVSSGWGEMPNVHSKTENSWGEPSSPST---LVDNGTAAWGKPPSSG 838

Query: 1971 SGWSS--SRGPYESGSG----HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQ------ 2018
            SGW    +  P   G       +S L    S+S Q  G+G  G     S++  +      
Sbjct: 839  SGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQ-EGWGSGGDEMNLSTSQWEDEEGDV 897

Query: 2019 -HGSASGQS-SSCGQHGASSGQSSSHGQHGSGSSQSS 2053
             + +AS +S SSC   G +  +    G   SG    +
Sbjct: 898  WNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEA 934



 Score = 77.4 bits (189), Expect = 2e-13
 Identities = 149/712 (20%), Positives = 259/712 (36%), Gaps = 81/712 (11%)

Query: 2059 GSGSGQSPGHGQRGSGSR-------QSPSYGRHGSGSGRSSSSGQH----GPGLGESSGF 2107
            GS  G   GH ++ +G+        QSPS  +   G+G ++S+G      G   G SSG 
Sbjct: 4    GSAQGNFTGHTKKTNGNNGTNGALVQSPS-NQSALGAGGANSNGSAARVWGVATGSSSGL 62

Query: 2108 GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSR 2167
             H   S G     +  G G   +  +G   S +G +     + + +              
Sbjct: 63   AHCSVSGGDGKMDTMIGDGRSQNC-WGASNSNAGINLNLNPNANPAAWPVL--------- 112

Query: 2168 QSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRG---PYESRSGHSSVF 2224
                 G +G+ +  +PS       +   +   Q+G+ +G   + G   P ES    +S  
Sbjct: 113  -----GHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTST- 166

Query: 2225 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSG-- 2282
             Q+ S S      +  G  + +  +   +   + Q++     G + G  +    H  G  
Sbjct: 167  SQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLP 226

Query: 2283 SSQSSSYGQQGSGSGQSPSRGRHG-----SGSGHSSSYGQHGSGSGWSS--SSGRHGSGS 2335
             +  SS  Q   GS +  S    G       +G+S+S    G+G   +S  S+ ++GS S
Sbjct: 227  GANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSS 286

Query: 2336 G---QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSS 2392
                + SG    +S      G    G GSG++     H    G  SR   +G +      
Sbjct: 287  AVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKP 346

Query: 2393 YGQHGSGSRQSLGH--GQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPY 2450
              QH +      G    +  S + Q+P+   G     S   ++ S   +  G S   G +
Sbjct: 347  PNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNH 406

Query: 2451 ESGSGHSSGLGHRESRSG--------------------QSSGYG-----QHGSSSGHSST 2485
              GS    G G    R                       ++G+G     Q+ +     S 
Sbjct: 407  NEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESP 466

Query: 2486 HGQHGSTSG-QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSG 2544
              +  + +G ++  C    AS+    + G   + ++ SS  G   +     P +   G  
Sbjct: 467  RSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDS 526

Query: 2545 SRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYG 2604
            + ++PS G    G   SS++    +       +    +   +S ++ +         G G
Sbjct: 527  NNKAPS-GPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDG 585

Query: 2605 QHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQG--SGSGQSPSRGRHGSGL 2662
            Q  S    S+ G   G  + SSS  G  G G +  SG       SGSG + +     SG 
Sbjct: 586  QR-SNPAWSAGG---GDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGW 641

Query: 2663 GHS-SSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSG 2713
            G+S ++    G+  G +   GP ++    S     + S  G +++  Q G+G
Sbjct: 642  GNSTNTKANPGTNWGETLKPGPQQN--WASKPQDNNVSNWGGAASVKQTGTG 691



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 144/656 (21%), Positives = 233/656 (35%), Gaps = 94/656 (14%)

Query: 169 HNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQS 228
           H S SG          D    +  G   S +G + N   + + +            +G  
Sbjct: 64  HCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNP 123

Query: 229 SGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQ---HGSRSGQSSRGERHRSSSGSSSSYGQ 285
           S      S+ GQ+ G +Q+G+ +G    +G      S   Q+S  + + S S    +   
Sbjct: 124 SSICSPVSAIGQNMG-NQNGNPTGTLGAWGNLLPQESTEPQTSTSQ-NVSFSAQPQNLNT 181

Query: 286 HGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQT 345
            G  +   +        + Q+      G   G  +    H  G       G   S   Q 
Sbjct: 182 DGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLP-----GANGSSVSQV 236

Query: 346 SGFGQHESGSGQSSGYSKHGSGSGHSSS---QGQHGSTSGQASSSGQHGSSSRQSSSYGQ 402
           SG G  E  S    G S     +G+S+S   QG +G T   A S+ Q+GSSS        
Sbjct: 237 SG-GSAEGISNSVWGLSPGNPATGNSNSGFSQG-NGDTVNSALSAKQNGSSS-------- 286

Query: 403 HESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYS 462
             +  +  SG     SG    PG    G GSG +     H   +G  S S        + 
Sbjct: 287 --AVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWG 344

Query: 463 SGFGHHESSSEHSSGYTQHGS------------GSGHSSGHGQHGSRSGQSSRGERQGSS 510
                H +S  +  G T   S            G  H +   +  S    +S G   GS 
Sbjct: 345 KPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSG 404

Query: 511 AGSSSSYGQHGSGSRQ-------SLGHSR-----------HGSGSGQSP----------- 541
             +  S G+ G+G  +         GH +             +G GQ+P           
Sbjct: 405 NHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEE 464

Query: 542 SP-SRGRHESGSR-------QSSSYGPHGYGSGRSSSRGPYESG------SGHSSGLGHQ 587
           SP S  ++++G+        Q+S+ G    GS  +S+     SG      +   +  G  
Sbjct: 465 SPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG 524

Query: 588 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSS 647
           +S +   SG G  G S   ++      + SG + S    GA + +  S      G     
Sbjct: 525 DSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWS----GAANQEDKSPTW---GEPPKP 577

Query: 648 RYGQQGSGSGQSPSRGRHGSDFGHSSSYGQH-----GSGSGWSSSNGPHGSVSGQSSGFG 702
           +    G G   +P+    G D+  SSS   H      +GSGW + +   GS    ++  G
Sbjct: 578 KSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSG 637

Query: 703 HKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSG 758
           + SG G S+  ++   G++     +    ++  S   + + S+ G ++S  Q G+G
Sbjct: 638 N-SGWGNSTN-TKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTG 691



 Score = 62.4 bits (150), Expect = 6e-09
 Identities = 106/463 (22%), Positives = 168/463 (36%), Gaps = 42/463 (9%)

Query: 128 SHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSH 187
           S S  S G  +  S +V G L PG  +     S     +G   + +  +   G  ++   
Sbjct: 232 SVSQVSGGSAEGISNSVWG-LSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQK 290

Query: 188 QSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQH 247
           + SG     SG    P     G GSG +   + H    G  S  + +  +       +QH
Sbjct: 291 EGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQH 350

Query: 248 GSGSGHSSGYGQHGSRSGQSSR-----GERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSG 302
            +   +  G     S S  S       G  H +S   ++S     SG+  S G    GSG
Sbjct: 351 SNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAAS-----SGTTASEG-SSDGSG 404

Query: 303 SRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFG-----QHESGSGQ 357
           +    S  R G+G G     G    G      R   +      +G+G     Q+ +   +
Sbjct: 405 NHNEGSTGREGTGEGRRRDKGIIDQG-HIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFE 463

Query: 358 SSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHS 417
            S  S+  + +G  +     G  + QAS+SG            G+++ +  +S+     S
Sbjct: 464 ESPRSERKNDNGTEA----WGCAATQASNSG------------GKNDGSIMNSTNTSSVS 507

Query: 418 SGSGQSPGHGQRGSGSGQSPSSGQHGTG-FGRSSSSGPYVSGSGYSSGFGHHESSSEHSS 476
                 P      +G G S +    G G +G S SS    + +   SG     ++++   
Sbjct: 508 GWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDK 567

Query: 477 GYTQHGSGSGHSSGHGQHGSRSGQS-SRGERQGSSAGSSSSYGQHGSGSRQSLG--HSRH 533
             T  G      S H   G RS  + S G   G  A SSS  G  G G +   G     +
Sbjct: 568 SPT-WGEPPKPKSQHWGDGQRSNPAWSAG--GGDWADSSSVLGHLGDGKKNGSGWDADSN 624

Query: 534 GSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES 576
            SGSG + +   G    G+  ++   P G   G +   GP ++
Sbjct: 625 RSGSGWNDTTRSGNSGWGNSTNTKANP-GTNWGETLKPGPQQN 666



 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 85/372 (22%), Positives = 132/372 (35%), Gaps = 32/372 (8%)

Query: 2452 SGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTS------------GQSSSC 2499
            +GS   +  GH +  +G +   G    S  + S  G  G+ S            G SS  
Sbjct: 3    TGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGL 62

Query: 2500 GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS-GS 2558
                 S G        G G SQ+  +G   S +G +       + +   P  G  G+  +
Sbjct: 63   AHCSVSGGDGKMDTMIGDGRSQNC-WGASNSNAGINLNLNPNANPAAW-PVLGHEGTVAT 120

Query: 2559 GRSSSSGQHGSGLGESSG--FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 2616
            G  SS     S +G++ G   G+   + G   +     S    +S   Q+ S S Q    
Sbjct: 121  GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTS-TSQNVSFSAQPQNL 179

Query: 2617 ERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL--GHSSSHGQHGSG 2674
               G ++ +  +   +   + Q++G    G   G       H  GL   + SS  Q   G
Sbjct: 180  NTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGG 239

Query: 2675 SGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD 2734
            S    S          +SV+G         ++ S    G+G   +       +G SS   
Sbjct: 240  SAEGIS----------NSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQ 289

Query: 2735 QEGSSTGQSSSYGHRGSG-SSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSG 2793
            +EGS      S    G G  +   G G +G G+  S + G H S S  +   G+ G    
Sbjct: 290  KEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWG-HPSRSTSNGVNGEWGKPPN 348

Query: 2794 QSSGYSQHGSGS 2805
            Q S    +G GS
Sbjct: 349  QHSNSDINGKGS 360



 Score = 38.1 bits (87), Expect = 0.13
 Identities = 94/485 (19%), Positives = 173/485 (35%), Gaps = 58/485 (11%)

Query: 101 LRDDTHQHQEEQEETEKEENKRQES---SFSHSSWSAGENDSYSRNVRG--SLKPGTESI 155
           ++ +T    EE   +E++ +   E+   + + +S S G+ND    N     S+     + 
Sbjct: 454 VKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAP 513

Query: 156 SRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGR----GQCGSGSG----QSPNYGQ 207
              +     +   +N        +G+  S +  S+      G   SG+     +SP +G+
Sbjct: 514 PAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGE 573

Query: 208 HGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQH-GSGSGHSSGYGQHGSRSGQ 266
                 Q       G G   +  +S        SS    H G G  + SG+    +RSG 
Sbjct: 574 PPKPKSQH-----WGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGS 628

Query: 267 SSRGERHRSSSG---SSSSYGQHGSGSRQSLGHG-RQGSGSRQSPSHVRHGSGSGHSSSH 322
                    +SG   S+++    G+   ++L  G +Q   S+   ++V +  G+      
Sbjct: 629 GWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQT 688

Query: 323 GQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQ-----SSGYSKHGSGSGHSS---SQ 374
           G    G          +  S + +G+ +    S +       G S  G  S +++   + 
Sbjct: 689 GTGWIGGPVPVK----QKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNM 744

Query: 375 GQHGSTSGQASSSGQHGSSSRQSSSYGQH--ESASRHSSGR--------GQHSSGSGQSP 424
               +   Q+S++    +++  ++S   H  E+   H +G         G  SSG G+ P
Sbjct: 745 WDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGWGEMP 804

Query: 425 GHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSS-------GFGH------HESS 471
               +   S   PSS       G ++   P  SGSG+          FG         + 
Sbjct: 805 NVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASAL 864

Query: 472 SEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHS 531
            + +S   Q G GSG    +        +        +S  S+SS    G+  ++ L   
Sbjct: 865 CKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKG 924

Query: 532 RHGSG 536
              SG
Sbjct: 925 MKTSG 929


>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
          Length = 398

 Score =  105 bits (261), Expect = 8e-22
 Identities = 108/367 (29%), Positives = 151/367 (41%), Gaps = 57/367 (15%)

Query: 1630 GLGESSGFGHHESSSGQSSSYSQ-HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSR 1688
            G GE+      E S+G +   +  HG G   S G G+   +    + G      S+ S  
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAG------SKVSEA 70

Query: 1689 YGQHGSGSRQSSGHG-RQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGS--------GRSS 1739
             GQ   G+R++ G G RQ  G G + + G       H+  +  H  G         G  +
Sbjct: 71   LGQ---GTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADA 127

Query: 1740 SRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS------GHFCSQGQHGSTSGQSSTF 1793
             RG ++   GH+   G  E+  GH    SQ G G       G   +   HG     + +F
Sbjct: 128  VRGSWQGVPGHN---GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSF 184

Query: 1794 --DQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGR-------HGSGSGHSSS 1844
              + +G+  GQ  + G    G++   +  Q G GS ++ ++          GSG G S+S
Sbjct: 185  GMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNS 244

Query: 1845 YGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRS 1904
             G  GS SG SS SG +G  +  SS  G   SSS  SSG +  GS  G S +    G   
Sbjct: 245  GGGSGSQSG-SSGSGSNGDNNNGSSSGG---SSSGSSSGGSSGGSSGGSSGN---SGGSR 297

Query: 1905 GQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR-GRHGSGSGQSSS 1963
            G S      GSS+GSSS              HG  G G+G  P   + G    GSG+S  
Sbjct: 298  GDSGSESSWGSSTGSSSG------------NHGGSGGGNGHKPGCEKPGNEARGSGESGI 345

Query: 1964 YGPYGSG 1970
             G  G G
Sbjct: 346  QGFRGQG 352



 Score =  104 bits (259), Expect = 1e-21
 Identities = 104/352 (29%), Positives = 147/352 (41%), Gaps = 50/352 (14%)

Query: 2114 SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHG 2173
            SG+ S+ +  G   GH  G G   S     + G+  G ++GS       G G+R++ G G
Sbjct: 26   SGEESTGTNIGEALGH--GLGDALSEGVGKAIGKEAGGAAGSKVSEAL-GQGTREAVGTG 82

Query: 2174 -RQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGS--------GRSSSRGPYESRSGHSSVF 2224
             RQ  G G + + G     + H+  +  H  G         G  + RG ++   GH+   
Sbjct: 83   VRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHN--- 139

Query: 2225 GQHESGSGHSSAYSQHGSGS------GHFCSQGQHGSTSGQSSTF--DQEGSSTGQSSSH 2276
            G  E+  GH    SQ G G       G   +   HG     + +F  + +G+  GQ  + 
Sbjct: 140  GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNG 199

Query: 2277 GQHGSGSSQSSSYGQQGSGSGQSPSRGR-------HGSGSGHSSSYGQHGSGSGWSSSSG 2329
            G    G++   +  Q G GS ++ ++          GSG G S+S G  GS SG SS SG
Sbjct: 200  GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG-SSGSG 258

Query: 2330 RHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGS 2389
             +G  +  SS  G   SSS  SSG +  GS  G S +    G   G S      GSS+GS
Sbjct: 259  SNGDNNNGSSSGG---SSSGSSSGGSSGGSSGGSSGN---SGGSRGDSGSESSWGSSTGS 312

Query: 2390 SSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR-GRHGSGSGQSSSYSPYGSG 2440
            SS              HG  G G+G  P   + G    GSG+S      G G
Sbjct: 313  SSG------------NHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352



 Score =  103 bits (257), Expect = 2e-21
 Identities = 110/379 (29%), Positives = 154/379 (40%), Gaps = 40/379 (10%)

Query: 1366 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSS 1425
            GSG       G+  +G+    + G HG G   S G G       ++ G    G+     S
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68

Query: 1426 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1485
                 G+R    + G R     G++ + G     +  +LG+  H  G     +    RHG
Sbjct: 69   EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124

Query: 1486 SGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSST 1545
            + + + S     G    W +S G    GS    GLG      GQ  G   +    G    
Sbjct: 125  ADAVRGSWQGVPGHNGAWETSGGHGIFGSQ--GGLG------GQGQG---NPGGLGTPWV 173

Query: 1546 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 1605
            HG  G+++G S      GA  GQ  + G    G++      + G GS ++    +  +  
Sbjct: 174  HGYPGNSAG-SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNP 232

Query: 1606 RQSPSYG-RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG-- 1662
              S S G    SG G  S SG  GSG   S+G  ++ SSSG SSS S  G  SG SSG  
Sbjct: 233  PPSGSGGGSSNSGGGSGSQSGSSGSG---SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGS 289

Query: 1663 YGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGH-------GRQGSGSGQSPSR 1715
             G  G   G S      GSS+ SSS  G HG GS   +GH       G +  GSG+S  +
Sbjct: 290  SGNSGGSRGDSGSESSWGSSTGSSS--GNHG-GSGGGNGHKPGCEKPGNEARGSGESGIQ 346

Query: 1716 GRHGSGLGHSSSHGQHGSG 1734
            G  G G+  +  + +   G
Sbjct: 347  GFRGQGVSSNMRNSETSPG 365



 Score =  103 bits (257), Expect = 2e-21
 Identities = 106/379 (27%), Positives = 143/379 (37%), Gaps = 53/379 (13%)

Query: 1836 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 1895
            GSG       G+  +G+    + G HG G   S G G       ++ G    G+     S
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68

Query: 1896 SYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1955
                 G+R    + G +     G++ + G     +  +LG+  H  G     +    RHG
Sbjct: 69   EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124

Query: 1956 SGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST 2015
            + + + S  G  G    W +S G    GS    GLG            GQ   + G   T
Sbjct: 125  ADAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------------GQGQGNPGGLGT 170

Query: 2016 HGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2075
               HG     + S G +     Q +  GQ G+G   + G   QG+ +   PG+G   + +
Sbjct: 171  PWVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASN 224

Query: 2076 RQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2135
            +         SGSG  SS+   G G           S SG S S S   + +G SSG   
Sbjct: 225  QNEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSS 273

Query: 2136 HGSRSGQSSRGERHGSSSGSSSRYGQHGSGS-------RQSSGHGRQGSGSGHSP---SR 2185
             GS SG SS G   GSS  S    G  GS S         S  HG  G G+GH P     
Sbjct: 274  SGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP 333

Query: 2186 GRHGSGSGHSSSHGQHGSG 2204
            G    GSG S   G  G G
Sbjct: 334  GNEARGSGESGIQGFRGQG 352



 Score =  100 bits (249), Expect = 2e-20
 Identities = 103/352 (29%), Positives = 145/352 (41%), Gaps = 50/352 (14%)

Query: 1174 SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHG 1233
            SG+ S+ +  G   GH  G G   S     + G+  G ++GS       G G+R++ G G
Sbjct: 26   SGEESTGTNIGEALGH--GLGDALSEGVGKAIGKEAGGAAGSKVSEAL-GQGTREAVGTG 82

Query: 1234 -RQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGS--------GRSSSRGPYESRSGHSSVF 1284
             RQ  G G + + G       H+  +  H  G         G  + RG ++   GH+   
Sbjct: 83   VRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHN--- 139

Query: 1285 GQHESGSGHSSAYSQHGSGS------GHFCSQGQHGSTSGQSSTF--DQEGSSTGQSSSY 1336
            G  E+  GH    SQ G G       G   +   HG     + +F  + +G+  GQ  + 
Sbjct: 140  GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNG 199

Query: 1337 GHRGSGSSQSSGYGRHGAGSGQSPSRGR-------HGSGSGHSSSYGQHGSGSGWSSSSG 1389
            G    G++      + G GS ++ ++          GSG G S+S G  GS SG SS SG
Sbjct: 200  GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG-SSGSG 258

Query: 1390 RHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGS 1449
             +G  +  SS  G   SSS  SSG +  GS  G S +    G   G S      GSS+GS
Sbjct: 259  SNGDNNNGSSSGG---SSSGSSSGGSSGGSSGGSSGN---SGGSRGDSGSESSWGSSTGS 312

Query: 1450 SSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR-GRHGSGSGQSSSYSPYGSG 1500
            SS              HG  G G+G  P   + G    GSG+S      G G
Sbjct: 313  SSG------------NHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352



 Score = 99.4 bits (246), Expect = 5e-20
 Identities = 105/379 (27%), Positives = 141/379 (37%), Gaps = 53/379 (13%)

Query: 2306 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 2365
            GSG       G+  +G+    + G HG G   S G G       ++ G    G+     S
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68

Query: 2366 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 2425
                 G+R    + G R     G++ + G     +  +LG+  H  G     +    RHG
Sbjct: 69   EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124

Query: 2426 SGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST 2485
            + + + S     G    W +S G    GS    GLG            GQ   + G   T
Sbjct: 125  ADAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------------GQGQGNPGGLGT 170

Query: 2486 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2545
               HG     + S G +     Q +  GQ G+G   + G   QG+ +   PG+G   + +
Sbjct: 171  PWVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASN 224

Query: 2546 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2605
            +         SGSG  SS+   GSG           S SG S S S   + +G SSG   
Sbjct: 225  QNEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSS 273

Query: 2606 HGSRSGQSSRGERHGSSSGSSSHYGQHGSGS-------RQSSGHGRQGSGSGQSP---SR 2655
             GS SG SS G   GSS  S    G  GS S         S  HG  G G+G  P     
Sbjct: 274  SGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP 333

Query: 2656 GRHGSGLGHSSSHGQHGSG 2674
            G    G G S   G  G G
Sbjct: 334  GNEARGSGESGIQGFRGQG 352



 Score = 98.6 bits (244), Expect = 8e-20
 Identities = 115/386 (29%), Positives = 156/386 (40%), Gaps = 64/386 (16%)

Query: 430 GSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSS 489
           GSG      SG+  TG     + G +  G   S G G  ++  + + G     +GS  S 
Sbjct: 17  GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG--KAIGKEAGG----AAGSKVSE 69

Query: 490 GHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHE 549
             GQ G+R    + G RQ    G++ + G     +  +LG++ H  G             
Sbjct: 70  ALGQ-GTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIG------------- 114

Query: 550 SGSRQSSSYGPHGYGSGRSSSRG-PYESGSGHSSGLGHQESRSGQSSGYGQHGSSS---- 604
              RQ+     HG  + R S +G P  +G+  +SG GH     G   G G  G  +    
Sbjct: 115 ---RQAEDVIRHGADAVRGSWQGVPGHNGAWETSG-GH--GIFGSQGGLGGQGQGNPGGL 168

Query: 605 GHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGR 664
           G    HG  G+++G S      GA  GQ  + G    G++      Q G GS ++ ++  
Sbjct: 169 GTPWVHGYPGNSAG-SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE 227

Query: 665 -------HGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHG 717
                   GS  G S+S G  GS SG S S     + +G SSG       G SSG S  G
Sbjct: 228 GCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG-------GSSSGSSSGG 280

Query: 718 SGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSG-HGRQGSGSGHSP 776
           S           GS  G S  S   G S G S S    GS +  SSG HG  G G+GH P
Sbjct: 281 SSG---------GSSGGSSGNS---GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKP 328

Query: 777 SRVRHGS---SSGHSSSHGQHGSGTS 799
              + G+    SG S   G  G G S
Sbjct: 329 GCEKPGNEARGSGESGIQGFRGQGVS 354



 Score = 98.6 bits (244), Expect = 8e-20
 Identities = 106/378 (28%), Positives = 142/378 (37%), Gaps = 52/378 (13%)

Query: 897  GSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSS 956
            GSG       G   +G+    + G HG G   S G G   + G+ +G    G+     S 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG--KAIGKEAG----GAAGSKVSE 69

Query: 957  YEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGS 1016
                G+R    +   Q     G++ + G     +  +LG+  H  G     +    RHG+
Sbjct: 70   ALGQGTREAVGTGVRQV-PGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHGA 125

Query: 1017 GSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 1076
             + + S  G       W +S G    GS    GLG            GQ   + G   T 
Sbjct: 126  DAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------------GQGQGNPGGLGTP 171

Query: 1077 GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 1136
              HG     + S G +     Q +  GQ G+G   + G   QG+ +   PG+G   + ++
Sbjct: 172  WVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASNQ 225

Query: 1137 QSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQH 1196
                     SGSG  SS+   GSG           S SG S S S   + +G SSG    
Sbjct: 226  NEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSSS 274

Query: 1197 GSRSGQSSRGERHGSSSGSSSHYGQHGSGS-------RQSSGHGRQGSGSGHSP---SRG 1246
            GS SG SS G   GSS  S    G  GS S         S  HG  G G+GH P     G
Sbjct: 275  GSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG 334

Query: 1247 RHGSGLGHSSSHGQHGSG 1264
                G G S   G  G G
Sbjct: 335  NEARGSGESGIQGFRGQG 352



 Score = 98.2 bits (243), Expect = 1e-19
 Identities = 110/403 (27%), Positives = 154/403 (38%), Gaps = 60/403 (14%)

Query: 1706 GSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 1765
            GSG       G   +G     + G HG G   S   G            G+   G+  S 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66

Query: 1766 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 1825
                 G G+      G        ++  D  G+  G+++    H  G++     G+Q   
Sbjct: 67   VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAA----HALGNT-GHEIGRQAED 119

Query: 1826 ---SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 1882
                G    RG      GH+ ++   G    + S  G  G G G   G G    + W   
Sbjct: 120  VIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVH- 174

Query: 1883 GYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 1942
            GY  + +GS         G+  GQ   G      + +  +  Q G GS ++    +  + 
Sbjct: 175  GYPGNSAGS---FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT- 230

Query: 1943 SGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2002
               +P PS    GSG G S+S G  GS SG         SGSG +      ++ +G SSG
Sbjct: 231  ---NPPPS----GSGGGSSNSGGGSGSQSG--------SSGSGSNG-----DNNNGSSSG 270

Query: 2003 YGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSG 2061
                GSSSG SS     G +SG SS  G  G S G S S    GS +  SSG +G  G G
Sbjct: 271  GSSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGG 323

Query: 2062 SGQSPG---HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGL 2101
            +G  PG    G    GS +S   G  G G   +  + +  PG+
Sbjct: 324  NGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPGM 366



 Score = 98.2 bits (243), Expect = 1e-19
 Identities = 111/401 (27%), Positives = 157/401 (39%), Gaps = 74/401 (18%)

Query: 365 GSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSP 424
           GSG       G+  + +    + G HG     S   G+           G+ + G+  S 
Sbjct: 17  GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGK---------AIGKEAGGAAGSK 66

Query: 425 GHGQRGSGSGQSPSSG-QHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGS 483
                G G+ ++  +G +   GFG + + G  V  + ++ G   HE   + +    +HG+
Sbjct: 67  VSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQ-AEDVIRHGA 125

Query: 484 GS---------GH------SSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSL 528
            +         GH      S GHG  GS+ G   +G+      G+   +G  G+ S  S 
Sbjct: 126 DAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-SAGSF 184

Query: 529 GHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRG-----PYESGSGHSSG 583
           G +  G+  GQ  +   G    G+    +    GYGS R+S++      P  SGSG  S 
Sbjct: 185 GMNPQGAPWGQGGNG--GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS- 241

Query: 584 LGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGS 643
                S SG  SG  Q GSS   S+    +GS+SG SSS    G++SG SS         
Sbjct: 242 -----SNSGGGSG-SQSGSSGSGSNGDNNNGSSSGGSSS----GSSSGGSSG-------- 283

Query: 644 SQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNG-PHGSVSGQSSGFG 702
                 G  G  SG S              S G  GS S W SS G   G+  G   G G
Sbjct: 284 ------GSSGGSSGNS------------GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNG 325

Query: 703 HKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHG 743
           HK G  +  G    GSG S   G+R  G  S   +     G
Sbjct: 326 HKPGC-EKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPG 365



 Score = 97.8 bits (242), Expect = 1e-19
 Identities = 116/413 (28%), Positives = 161/413 (38%), Gaps = 67/413 (16%)

Query: 1236 GSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 1295
            GSG       G   +G     + G HG G   S   G            G+   G+  S 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66

Query: 1296 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS-SYGHRGSG-SSQSSGYGRHG 1353
                 G G+      G        ++  D  G+  G+++ + G+ G     Q+    RHG
Sbjct: 67   VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAAHALGNTGHEIGRQAEDVIRHG 124

Query: 1354 AGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 1413
            A +     RG      GH+ ++   G    + S  G  G G G   G G    + W    
Sbjct: 125  ADA----VRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVHG- 175

Query: 1414 CTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1473
               +   S  S      G+  GQ   G      + +  +  Q G GS ++    +  +  
Sbjct: 176  ---YPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT-- 230

Query: 1474 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGY 1533
              +P PS    GSG G S+S    G GSG        +SGSS S   G  ++ +G SSG 
Sbjct: 231  --NPPPS----GSGGGSSNS----GGGSG-------SQSGSSGSGSNG--DNNNGSSSGG 271

Query: 1534 GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSGS 1592
               GSSSG SS     G +SG SS  G  G S G S S    GS +  SSG +G  G G+
Sbjct: 272  SSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGN 324

Query: 1593 GQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 1645
            G  PG  + G+ +R          GSG S   G  G G+  SS   + E+S G
Sbjct: 325  GHKPGCEKPGNEAR----------GSGESGIQGFRGQGV--SSNMRNSETSPG 365



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 114/414 (27%), Positives = 160/414 (38%), Gaps = 69/414 (16%)

Query: 2176 GSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 2235
            GSG       G   +G+    + G HG G   S   G            G+   G+  S 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66

Query: 2236 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 2295
                 G G+      G        ++  D  G+  G+++    H  G++     G+Q   
Sbjct: 67   VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAA----HALGNT-GHEIGRQAED 119

Query: 2296 ---SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 2352
                G    RG      GH+ ++   G    + S  G  G G G   G G    + W   
Sbjct: 120  VIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVH- 174

Query: 2353 GYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 2412
            GY  + +GS         G+  GQ   G      + +  +  Q G GS ++    +  + 
Sbjct: 175  GYPGNSAGS---FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT- 230

Query: 2413 SGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2472
               +P PS    GSG G S+S    G GSG         S SG S    + ++ +G SSG
Sbjct: 231  ---NPPPS----GSGGGSSNS----GGGSG---------SQSGSSGSGSNGDNNNGSSSG 270

Query: 2473 YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSG 2531
                GSSSG SS     G +SG SS  G  G S G S S    GS +  SSG +G  G G
Sbjct: 271  GSSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGG 323

Query: 2532 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 2585
            +G  PG  + G+ +R          GSG S   G  G G+  SS   + E+S G
Sbjct: 324  NGHKPGCEKPGNEAR----------GSGESGIQGFRGQGV--SSNMRNSETSPG 365



 Score = 96.7 bits (239), Expect = 3e-19
 Identities = 113/402 (28%), Positives = 152/402 (37%), Gaps = 61/402 (15%)

Query: 782  GSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQ 841
            GS        G+  +GT+   + GH   G G A   G    G   G  + G A+G   S+
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALGH---GLGDALSEGV---GKAIG-KEAGGAAGSKVSE 69

Query: 842  GRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSG 901
                 T     +  +     G + + G     + HA G   H  G               
Sbjct: 70   ALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-------------- 115

Query: 902  QSPSYGRHGSGSGRSSSSG--RHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQ 959
            Q+    RHG+ + R S  G   H      S G G   S G   G  Q   G   +     
Sbjct: 116  QAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHG 175

Query: 960  HGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG-----RH 1014
            +   S  S      G+  G   + G    G+       Q G GS ++ + + G       
Sbjct: 176  YPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS 235

Query: 1015 GSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 1074
            GSG G S+S G    GSG         S SG S    + ++ +G SSG    GSSSG SS
Sbjct: 236  GSGGGSSNSGG----GSG---------SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSS 282

Query: 1075 THGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSGSGQSPGHGQRGS 1133
                 G +SG SS  G  G S G S S    GS +  SSG +G  G G+G  PG  + G+
Sbjct: 283  -----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGN 335

Query: 1134 GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 1175
             +R          GSG S   G  G G+  SS   + E+S G
Sbjct: 336  EAR----------GSGESGIQGFRGQGV--SSNMRNSETSPG 365



 Score = 95.9 bits (237), Expect = 5e-19
 Identities = 101/347 (29%), Positives = 148/347 (42%), Gaps = 46/347 (13%)

Query: 2493 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG--YGRQGSGSGQSPGHGQRGSGSRQSPS 2550
            SG+ S+    G + G++  HG  G   S+  G   G++  G+  S      G G+R++  
Sbjct: 26   SGEEST----GTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVG 80

Query: 2551 YG-RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS---------GH- 2599
             G R   G G + + G        + G   HE    Q+    +HG+ +         GH 
Sbjct: 81   TGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIRHGADAVRGSWQGVPGHN 139

Query: 2600 -----SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPS 2654
                 S G+G  GS+ G   +G+ +    G+   +G  G+ S  S G   QG+  GQ  +
Sbjct: 140  GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-SAGSFGMNPQGAPWGQGGN 198

Query: 2655 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGS 2714
             G    G     +  Q G GS R+S++        +        SGSG  S+ S  GSGS
Sbjct: 199  GGPPNFGTNTQGAVAQPGYGSVRASNQ--------NEGCTNPPPSGSGGGSSNSGGGSGS 250

Query: 2715 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSG--YGRHGAGSGQSLSH 2772
                   Q GS+   S+  +  GSS+G SSS    G  S  SSG   G  G   G S S 
Sbjct: 251  -------QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303

Query: 2773 GRHGSGSGQSS-SYGQHGSGSGQSSGYSQHGS---GSGQDGYSYCKG 2815
               GS +G SS ++G  G G+G   G  + G+   GSG+ G    +G
Sbjct: 304  SSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350



 Score = 95.1 bits (235), Expect = 9e-19
 Identities = 102/338 (30%), Positives = 139/338 (41%), Gaps = 41/338 (12%)

Query: 2001 SGYGQHGSSSGHSSTHGQHGSAS-GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG-RQ 2058
            SG    G++ G +  HG   + S G   + G+    +  S      G G+ ++ G G RQ
Sbjct: 26   SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85

Query: 2059 GSGSGQSPGHGQRGSGS------------RQSPSYGRHGSGSGRSSSSGQHGP-GLGESS 2105
              G G +   G R   +            RQ+    RHG+ + R S  G  G  G  E+S
Sbjct: 86   VPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETS 145

Query: 2106 G----FGHHESSSGQSSSYSQHGSGSGHSSGY-GQHGSRSGQSSRGERHGSS-SGSSSRY 2159
            G    FG      GQ    +  G G+    GY G      G + +G   G   +G    +
Sbjct: 146  GGHGIFGSQGGLGGQGQG-NPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNF 204

Query: 2160 GQHGSGSRQSSGHG-----RQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPY 2214
            G +  G+    G+G      Q  G  + P  G   SG G S+S G  GS SG S S    
Sbjct: 205  GTNTQGAVAQPGYGSVRASNQNEGCTNPPPSG---SGGGSSNSGGGSGSQSGSSGSGSNG 261

Query: 2215 ESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS 2274
            ++ +G SS      S SG SS  S  GS  G   S G  G + G S +    GSSTG SS
Sbjct: 262  DNNNGSSS----GGSSSGSSSGGSSGGSSGG---SSGNSGGSRGDSGSESSWGSSTGSSS 314

Query: 2275 -SHGQHGSGSSQS---SSYGQQGSGSGQSPSRGRHGSG 2308
             +HG  G G+         G +  GSG+S  +G  G G
Sbjct: 315  GNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 114/378 (30%), Positives = 152/378 (40%), Gaps = 52/378 (13%)

Query: 682  SGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQ 741
            SG  S+    G   G   G     G G++ G    G+  S  S     G+R    +   Q
Sbjct: 26   SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85

Query: 742  ---HGSSSGLSSSYGQ--HGSGSHQSSGH--GRQGSGSGHSPSRVRHGSSSGHSSSHGQH 794
                G++  L +  G+  H  G+   +GH  GRQ          +RHG+ +   S  G  
Sbjct: 86   VPGFGAADALGNRVGEAAHALGN---TGHEIGRQAEDV------IRHGADAVRGSWQGVP 136

Query: 795  GSGTSCSSSCGHYESGS-GQASGFGQHESGSGQG----YSQHGSASGHFSSQGRHGSTSG 849
            G   +  +S GH   GS G   G GQ   G G G    +   G+++G F    + G+  G
Sbjct: 137  GHNGAWETSGGHGIFGSQGGLGGQGQGNPG-GLGTPWVHGYPGNSAGSFGMNPQ-GAPWG 194

Query: 850  QSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRH 909
            Q  + G  +  +    +  Q    S  AS +    +    S      GSG G S S G  
Sbjct: 195  QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS------GSGGGSSNSGGGS 248

Query: 910  GSGSGRSSSSGRHGSGSGQSSGFGHK-SSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSS 968
            GS SG S S     + +G SSG     SSSG SSG      GS   SS    GSR G S 
Sbjct: 249  GSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG------GSSGGSSGNSGGSR-GDSG 301

Query: 969  RSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR-GRHGSGSGQSSSYGPY 1027
                 GSS+GSSS              HG  G G+G  P   + G    GSG+S   G +
Sbjct: 302  SESSWGSSTGSSSG------------NHGGSGGGNGHKPGCEKPGNEARGSGESGIQG-F 348

Query: 1028 RSGSGWSSSRGPYESGSG 1045
            R G G SS+    E+  G
Sbjct: 349  R-GQGVSSNMRNSETSPG 365



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 102/338 (30%), Positives = 141/338 (41%), Gaps = 41/338 (12%)

Query: 1061 SGYGQHGSSSGHSSTHGQHGSTS-GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG-RQ 1118
            SG    G++ G +  HG   + S G   + G+    +  S      G G+ ++ G G RQ
Sbjct: 26   SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85

Query: 1119 GSGSGQSPGHGQRGSGS------------RQSPSYGRHGSGSGRSSSSGQHG-SGLGESS 1165
              G G +   G R   +            RQ+    RHG+ + R S  G  G +G  E+S
Sbjct: 86   VPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETS 145

Query: 1166 G----FGHHESSSGQSSSYSQHGSGSGHSSGY-GQHGSRSGQSSRGERHGSS-SGSSSHY 1219
            G    FG      GQ    +  G G+    GY G      G + +G   G   +G   ++
Sbjct: 146  GGHGIFGSQGGLGGQGQG-NPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNF 204

Query: 1220 GQHGSGSRQSSGHG-----RQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPY 1274
            G +  G+    G+G      Q  G  + P  G   SG G S+S G  GS SG S S    
Sbjct: 205  GTNTQGAVAQPGYGSVRASNQNEGCTNPPPSG---SGGGSSNSGGGSGSQSGSSGSGSNG 261

Query: 1275 ESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS 1334
            ++ +G SS      S SG SS  S  GS  G   S G  G + G S +    GSSTG SS
Sbjct: 262  DNNNGSSS----GGSSSGSSSGGSSGGSSGG---SSGNSGGSRGDSGSESSWGSSTGSSS 314

Query: 1335 -SYGHRGSGSSQSSGY---GRHGAGSGQSPSRGRHGSG 1368
             ++G  G G+    G    G    GSG+S  +G  G G
Sbjct: 315  GNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352



 Score = 92.0 bits (227), Expect = 7e-18
 Identities = 109/371 (29%), Positives = 146/371 (39%), Gaps = 31/371 (8%)

Query: 484 GSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSP 543
           GSG + G  Q G  S  ++ GE  G   G + S G   +  +++ G     +GS  S + 
Sbjct: 17  GSGEA-GPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGG----AAGSKVSEAL 71

Query: 544 SRGRHES---GSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQES-RSGQSSGYGQ 599
            +G  E+   G RQ   +G       R          +GH  G   ++  R G  +  G 
Sbjct: 72  GQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131

Query: 600 HGSSSGHSS---THGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQ--QGS 654
                GH+    T G HG    Q    GQ     G   +   HG   + +  +G   QG+
Sbjct: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGA 191

Query: 655 GSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYS 714
             GQ  + G          +  Q G GS  +S+     +    S   G  S SG  SG S
Sbjct: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG-S 250

Query: 715 QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGH 774
           Q GS  S S+G   +GS SG SS     G SSG SS     GS  +     G  GS S  
Sbjct: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG----GSSGNSGGSRGDSGSESSW 306

Query: 775 SPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSA 834
             S    GSSSG+   HG  G G      C   E    +A G G  ESG  QG+   G +
Sbjct: 307 GSST---GSSSGN---HGGSGGGNGHKPGC---EKPGNEARGSG--ESGI-QGFRGQGVS 354

Query: 835 SGHFSSQGRHG 845
           S   +S+   G
Sbjct: 355 SNMRNSETSPG 365



 Score = 89.0 bits (219), Expect = 6e-17
 Identities = 105/383 (27%), Positives = 145/383 (37%), Gaps = 49/383 (12%)

Query: 730  GSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQ--GSGSGHSPSRVRHGSSSGH 787
            GS      +S +  + + +  + G HG G   S G G+       G + S+V      G 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75

Query: 788  SSSHG---QHGSGTSCSSSCGHYESGSGQASGFGQHESG-SGQGYSQHGSASGHFSSQGR 843
              + G   +   G   + + G+    +  A G   HE G   +   +HG+ +   S QG 
Sbjct: 76   REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135

Query: 844  HGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSG-- 901
             G  +G   +SG H     Q    GQ         G+G  G G G    HG  G+ +G  
Sbjct: 136  PGH-NGAWETSGGHGIFGSQGGLGGQ---------GQGNPG-GLGTPWVHGYPGNSAGSF 184

Query: 902  ----QSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQ---HGSGSGHS 954
                Q   +G+ G+G     + G +  G+    G+G   +S Q+ G T     GSG G S
Sbjct: 185  GMNPQGAPWGQGGNGG--PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242

Query: 955  SSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH 1014
            +S    GS+SG S       +++GSSS     GS S         G  SG S   S G  
Sbjct: 243  NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSS---------GGSSGGSSGGSSGNS 293

Query: 1015 GSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 1074
            G   G S S       S W SS G   S SG+  G G            G     SG S 
Sbjct: 294  GGSRGDSGSE------SSWGSSTG---SSSGNHGGSGGGNGHKPGCEKPGNEARGSGESG 344

Query: 1075 THGQHGSTSGQSSSCGQHGASSG 1097
              G  G   G SS+      S G
Sbjct: 345  IQGFRG--QGVSSNMRNSETSPG 365



 Score = 88.6 bits (218), Expect = 8e-17
 Identities = 101/370 (27%), Positives = 147/370 (39%), Gaps = 35/370 (9%)

Query: 974  GSSSGSSSSYGQHGSGSR--QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGS 1031
            GS        G+  +G+   ++LGHG  G    +    + G+   G+  S        G+
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75

Query: 1032 GWSSSRGPYE-SGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG 1090
              +   G  +  G G +  LG+R   +  + G   H      +    +HG+ + + S  G
Sbjct: 76   REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQG 134

Query: 1091 QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG----HGQRGSGSR------QSPS 1140
              G +    +S G HG   SQ  G G QG G+    G    HG  G+ +       Q   
Sbjct: 135  VPGHNGAWETSGG-HGIFGSQG-GLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAP 192

Query: 1141 YGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ--HGSGSGHSSGYGQHGS 1198
            +G+ G+G     + G +  G     G+G   +S+      +    GSG G S+  G  GS
Sbjct: 193  WGQGGNGG--PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGS 250

Query: 1199 RSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGS----GLGH 1254
            +SG S  G    +++GSSS     GS S  SSG    GS      SRG  GS    G   
Sbjct: 251  QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSST 310

Query: 1255 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHG 1314
             SS G HG GSG  +   P   + G+ +       GSG S      G G     S  ++ 
Sbjct: 311  GSSSGNHG-GSGGGNGHKPGCEKPGNEA------RGSGESGIQGFRGQG---VSSNMRNS 360

Query: 1315 STSGQSSTFD 1324
             TS     FD
Sbjct: 361  ETSPGMFNFD 370



 Score = 88.6 bits (218), Expect = 8e-17
 Identities = 97/360 (26%), Positives = 145/360 (40%), Gaps = 30/360 (8%)

Query: 196 GSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSS 255
           GSG       G+  +G+    +   HG G   S G  +   + G+ +G +   +GS  S 
Sbjct: 17  GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGK---AIGKEAGGA---AGSKVSE 69

Query: 256 GYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSG 315
             GQ G+R    + G R     G++ + G     +  +LG+     G RQ+   +RHG+ 
Sbjct: 70  ALGQ-GTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIG-RQAEDVIRHGAD 126

Query: 316 SGHSSSHGQHGSGSSYSYSRGHYESGS-GQTSGFGQHESGSGQSS---GYSKHGSGSGHS 371
           +   S  G  G   ++  S GH   GS G   G GQ   G   +    GY  + +GS   
Sbjct: 127 AVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGM 186

Query: 372 SSQGQHGSTSGQAS--SSGQHGSSSRQSSSYGQHESASRHS---------SGRGQHSSGS 420
           + QG      G     + G +   +     YG   +++++          SG G  +SG 
Sbjct: 187 NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246

Query: 421 GQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQ 480
           G     G  GSGS    ++G    G    SSSG    GS   S  G+   S   S   + 
Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSS-GNSGGSRGDSGSESS 305

Query: 481 HGSGSGHSSG-HGQHGSRSGQSSRGERQGSSA---GSSSSYGQHGSGSRQSLGHSRHGSG 536
            GS +G SSG HG  G  +G     E+ G+ A   G S   G  G G   ++ +S    G
Sbjct: 306 WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPG 365



 Score = 88.6 bits (218), Expect = 8e-17
 Identities = 98/324 (30%), Positives = 129/324 (39%), Gaps = 32/324 (9%)

Query: 2516 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ-SPSYGRHGSGSGRSSSSGQHGSGLGES 2574
            G      SG    G+  G++ GHG   + S     + G+   G+  S  S   G G  E+
Sbjct: 19   GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78

Query: 2575 SGFGHHESSS-GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQ-- 2631
             G G  +    G + +       + H+ G   H     Q+    RHG+ +   S  G   
Sbjct: 79   VGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGVPG 137

Query: 2632 HGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHS 2691
            H      S GHG  GS  G       +  GLG    HG  G+ +G S    P  +  G  
Sbjct: 138  HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG-SFGMNPQGAPWGQG 196

Query: 2692 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGS 2751
               G    G+    A +Q G GS    +Q + G T+   S     GS  G S+S G  GS
Sbjct: 197  GNGGPPNFGTNTQGAVAQPGYGSVRASNQNE-GCTNPPPS-----GSGGGSSNSGGGSGS 250

Query: 2752 GSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYS 2811
             S  SSG G +G  +        +GS SG        GS SG SSG S  GS  G  G S
Sbjct: 251  QSG-SSGSGSNGDNN--------NGSSSG--------GSSSGSSSGGSSGGSSGGSSGNS 293

Query: 2812 YCKGGSNHDGGSSGSYFLSFPSST 2835
               GGS  D GS  S+  S  SS+
Sbjct: 294  ---GGSRGDSGSESSWGSSTGSSS 314



 Score = 88.2 bits (217), Expect = 1e-16
 Identities = 105/364 (28%), Positives = 143/364 (39%), Gaps = 54/364 (14%)

Query: 2471 SGYGQHGSSSGHSSTHGQHGSTS-GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG-RQ 2528
            SG    G++ G +  HG   + S G   + G+    +  S      G G+ ++ G G RQ
Sbjct: 26   SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85

Query: 2529 GSGSGQSPGHGQRGSGS------------RQSPSYGRHGSGSGRSSSSGQHG-SGLGESS 2575
              G G +   G R   +            RQ+    RHG+ + R S  G  G +G  E+S
Sbjct: 86   VPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETS 145

Query: 2576 G----FGHHESSSGQSSSYSQHGSGSGHSSGY-GQHGSRSGQSSRGERHGSS-SGSSSHY 2629
            G    FG      GQ    +  G G+    GY G      G + +G   G   +G   ++
Sbjct: 146  GGHGIFGSQGGLGGQGQG-NPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNF 204

Query: 2630 GQHGSGSRQSSGHG-----RQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPY 2684
            G +  G+    G+G      Q  G    P  G   SG G S+S G  GS SG S S    
Sbjct: 205  GTNTQGAVAQPGYGSVRASNQNEGCTNPPPSG---SGGGSSNSGGGSGSQSGSSGSGSNG 261

Query: 2685 ESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS 2744
            ++  G         S SG SS+ S  G  SG     G  G +SG S      G S G S 
Sbjct: 262  DNNNG---------SSSGGSSSGSSSGGSSG-----GSSGGSSGNS------GGSRGDSG 301

Query: 2745 SYGHRGSGSSQSSG-YGRHGAGSGQS---LSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQ 2800
            S    GS +  SSG +G  G G+G        G    GSG+S   G  G G   +   S+
Sbjct: 302  SESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSE 361

Query: 2801 HGSG 2804
               G
Sbjct: 362  TSPG 365



 Score = 88.2 bits (217), Expect = 1e-16
 Identities = 104/342 (30%), Positives = 137/342 (40%), Gaps = 49/342 (14%)

Query: 1531 SGYGQHGSSSGHSSTHGQHGSTS-GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG-RQ 1588
            SG    G++ G +  HG   + S G   + G+    +  S      G G+ ++ G G RQ
Sbjct: 26   SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85

Query: 1589 GSGSGQSPGHGQRGSGS------------RQSPSYGRHGSGSGRSSSSGQHG-SGLGESS 1635
              G G +   G R   +            RQ+    RHG+ + R S  G  G +G  E+S
Sbjct: 86   VPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETS 145

Query: 1636 G----FGHHESSSGQSSSYSQ-------HG--SGSGHSSGYGQHGSRSGQSSRGERHGSS 1682
            G    FG      GQ             HG    S  S G    G+  GQ   G      
Sbjct: 146  GGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFG 205

Query: 1683 SRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGS--GSGRSSS 1740
            + +     Q G GS ++S    Q  G    P  G   SG G S+S G  GS  GS  S S
Sbjct: 206  TNTQGAVAQPGYGSVRASN---QNEGCTNPPPSG---SGGGSSNSGGGSGSQSGSSGSGS 259

Query: 1741 RGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST 1800
             G  ++ +G SS      S SG SS  S  GS  G   S G  G + G S +    GSST
Sbjct: 260  NG--DNNNGSSS----GGSSSGSSSGGSSGGSSGG---SSGNSGGSRGDSGSESSWGSST 310

Query: 1801 GQSS-SHGQHGSGSSQS---SSYGQQGSGSGQSPSRGRHGSG 1838
            G SS +HG  G G+         G +  GSG+S  +G  G G
Sbjct: 311  GSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352



 Score = 86.7 bits (213), Expect = 3e-16
 Identities = 82/303 (27%), Positives = 122/303 (40%), Gaps = 30/303 (9%)

Query: 180 GEQNSDSHQSSGRGQCGSGSGQSPNYGQH---GSGSGQSS---SNDTHGSGSGQSSGFSQ 233
           G + S++     R   G+G  Q P +G     G+  G+++    N  H  G  Q+    +
Sbjct: 64  GSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIR 122

Query: 234 HKSSS--GQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGS------------ 279
           H + +  G   G   H      S G+G  GS+ G   +G+ +    G+            
Sbjct: 123 HGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG 182

Query: 280 -------SSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYS 332
                   + +GQ G+G   + G   QG+ ++     VR  + +   ++    GSG   S
Sbjct: 183 SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242

Query: 333 YSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGS 392
            S G   S SG +      ++ +G SSG S  GS SG SS     GS+     S G  GS
Sbjct: 243 NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGS 302

Query: 393 SSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSG-SGQSPSSGQHGTGFGRSSS 451
            S   SS G        S G   H  G  + PG+  RGSG SG     GQ  +   R+S 
Sbjct: 303 ESSWGSSTGSSSGNHGGSGGGNGHKPGC-EKPGNEARGSGESGIQGFRGQGVSSNMRNSE 361

Query: 452 SGP 454
           + P
Sbjct: 362 TSP 364



 Score = 85.1 bits (209), Expect = 9e-16
 Identities = 94/363 (25%), Positives = 135/363 (37%), Gaps = 42/363 (11%)

Query: 640 GSGSSQSSRYGQQGSGSGQSPSRGRHGSDF---GHSSSYGQHGSGSGWSSSNGPHGSVSG 696
           GSG +   + G++ +G+    + G    D    G   + G+   G+  S  +   G  + 
Sbjct: 17  GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76

Query: 697 QS--------SGFGHKSGSGQSSGYSQHGSGSS-HSSGYR-----KHGSRSGQSSRSEQH 742
           ++         GFG     G   G + H  G++ H  G +     +HG+ + + S     
Sbjct: 77  EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVP 136

Query: 743 GSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSS 802
           G +    +S G    GS    G   QG+  G     V HG     + S G +  G     
Sbjct: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWV-HGYPGNSAGSFGMNPQGAPWG- 194

Query: 803 SCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGR-------HGSTSGQSSSSG 855
                + G+G    FG +  G+    +Q G  S   S+Q          GS  G S+S G
Sbjct: 195 -----QGGNGGPPNFGTNTQGA---VAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246

Query: 856 QHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGS---- 911
              S SG S S    ++ +  +SG    GS SG S G    GS      S G  GS    
Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306

Query: 912 GSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSE 971
           GS   SSSG HG   G   G GHK    +  G    GSG      +   G  S   +   
Sbjct: 307 GSSTGSSSGNHG---GSGGGNGHKPGC-EKPGNEARGSGESGIQGFRGQGVSSNMRNSET 362

Query: 972 QHG 974
             G
Sbjct: 363 SPG 365



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 61/182 (33%), Positives = 77/182 (42%), Gaps = 20/182 (10%)

Query: 132 WSAGEND---SYSRNVRGSL-KPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSH 187
           W  G N    ++  N +G++ +PG  S+  R S Q +  G  N     S   G  NS   
Sbjct: 193 WGQGGNGGPPNFGTNTQGAVAQPGYGSV--RASNQNE--GCTNPPPSGSGG-GSSNSGGG 247

Query: 188 QSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKS--SSGQSSGYS 245
             S  G  GSGS    N   +GS SG SSS  + G  SG SSG S   S  S G S   S
Sbjct: 248 SGSQSGSSGSGSNGDNN---NGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES 304

Query: 246 QHGSGSGHSSGY-----GQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQG 300
             GS +G SSG      G +G + G    G   R  SG S   G  G G   ++ +    
Sbjct: 305 SWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEAR-GSGESGIQGFRGQGVSSNMRNSETS 363

Query: 301 SG 302
            G
Sbjct: 364 PG 365


>gi|186928829 dermokine isoform 4 precursor [Homo sapiens]
          Length = 386

 Score =  104 bits (260), Expect = 1e-21
 Identities = 103/339 (30%), Positives = 145/339 (42%), Gaps = 42/339 (12%)

Query: 2114 SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHG 2173
            SG+ S+ +  G   GH  G G   S     + G+  G ++GS       G G+R++ G G
Sbjct: 26   SGEESTGTNIGEALGH--GLGDALSEGVGKAIGKEAGGAAGSKVSEAL-GQGTREAVGTG 82

Query: 2174 -RQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGS--------GRSSSRGPYESRSGHSSVF 2224
             RQ  G G + + G     + H+  +  H  G         G  + RG ++   GH+   
Sbjct: 83   VRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHN--- 139

Query: 2225 GQHESGSGHSSAYSQHGSGS------GHFCSQGQHGSTSGQSSTF--DQEGSSTGQSSSH 2276
            G  E+  GH    SQ G G       G   +   HG     + +F  + +G+  GQ  + 
Sbjct: 140  GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNG 199

Query: 2277 GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 2336
            G    G++   +  Q G GS ++ ++    +    S      GSG G S+S G  GS SG
Sbjct: 200  GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS------GSGGGSSNSGGGSGSQSG 253

Query: 2337 QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGE--RHGSSSGSSSSYG 2394
             SSG G        S+G   +GS SG SSS    G  SG SS G     G S G S S  
Sbjct: 254  -SSGSG--------SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES 304

Query: 2395 QHGSGSRQSLG-HGQHGSGSGQSPSPSR-GRHGSGSGQS 2431
              GS +  S G HG  G G+G  P   + G    GSG+S
Sbjct: 305  SWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGES 343



 Score =  103 bits (256), Expect = 3e-21
 Identities = 111/346 (32%), Positives = 148/346 (42%), Gaps = 25/346 (7%)

Query: 1174 SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHG 1233
            SG+ S+ +  G   GH  G G   S     + G+  G ++GS       G G+R++ G G
Sbjct: 26   SGEESTGTNIGEALGH--GLGDALSEGVGKAIGKEAGGAAGSKVSEAL-GQGTREAVGTG 82

Query: 1234 -RQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSG 1292
             RQ  G G + + G       H+   G  G   GR +       R G  +V G  +   G
Sbjct: 83   VRQVPGFGAADALGNRVGEAAHAL--GNTGHEIGRQAED---VIRHGADAVRGSWQGVPG 137

Query: 1293 HSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSS-GYGR 1351
            H+ A+   G G G F SQG  G   GQ      +G+  G  + + H   G+S  S G   
Sbjct: 138  HNGAWETSG-GHGIFGSQGGLG---GQG-----QGNPGGLGTPWVHGYPGNSAGSFGMNP 188

Query: 1352 HGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS 1411
             GA  GQ  + G    G+    +  Q G GS  +S+    G  +   SG G   S+S   
Sbjct: 189  QGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE-GCTNPPPSGSGGGSSNSGGG 247

Query: 1412 SGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGS 1471
            SG     SGSG S+    +GS SG SS G   G SSG SS      SG   S G     S
Sbjct: 248  SGSQSGSSGSG-SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG--SRGDSGSES 304

Query: 1472 GSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHS 1517
              G S   S G HG GSG  + + P G     + +RG  ESG  +S
Sbjct: 305  SWGSSTGSSSGNHG-GSGGGNGHKP-GCEKPGNEARGSGESGIQNS 348



 Score =  102 bits (255), Expect = 4e-21
 Identities = 106/354 (29%), Positives = 148/354 (41%), Gaps = 49/354 (13%)

Query: 1630 GLGESSGFGHHESSSGQSSSYSQ-HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSR 1688
            G GE+      E S+G +   +  HG G   S G G+   +    + G      S+ S  
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAG------SKVSEA 70

Query: 1689 YGQHGSGSRQSSGHG-RQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGS--------GRSS 1739
             GQ   G+R++ G G RQ  G G + + G       H+  +  H  G         G  +
Sbjct: 71   LGQ---GTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADA 127

Query: 1740 SRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS------GHFCSQGQHGSTSGQSSTF 1793
             RG ++   GH+   G  E+  GH    SQ G G       G   +   HG     + +F
Sbjct: 128  VRGSWQGVPGHN---GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSF 184

Query: 1794 --DQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSG 1851
              + +G+  GQ  + G    G++   +  Q G GS ++ ++    +    S      GSG
Sbjct: 185  GMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS------GSG 238

Query: 1852 SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGE 1911
             G S+S G  GS SG SSG G        S+G   +GS SG SSS    G  SG SS G 
Sbjct: 239  GGSSNSGGGSGSQSG-SSGSG--------SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGS 289

Query: 1912 --QHGSSSGSSSSYGQHGSGSRQSLG-HGQHGSGSGQSPSPSR-GRHGSGSGQS 1961
                G S G S S    GS +  S G HG  G G+G  P   + G    GSG+S
Sbjct: 290  SGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGES 343



 Score =  100 bits (249), Expect = 2e-20
 Identities = 107/357 (29%), Positives = 146/357 (40%), Gaps = 40/357 (11%)

Query: 2306 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 2365
            GSG       G+  +G+    + G HG G   S G G       ++ G    G+     S
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68

Query: 2366 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 2425
                 G+R    + G R     G++ + G     +  +LG+  H  G     +    RHG
Sbjct: 69   EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124

Query: 2426 SGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST 2485
            + + + S     G    W +S G    GS    GLG      GQ  G   +    G    
Sbjct: 125  ADAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------GQGQG---NPGGLGTPWV 173

Query: 2486 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2545
            HG  G+++G S      GA  GQ  + G    G++      + G GS ++    +  +  
Sbjct: 174  HGYPGNSAG-SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNP 232

Query: 2546 RQSPSYG-RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG-- 2602
              S S G    SG G  S SG  GSG   S+G  ++ SSSG SSS S  G  SG SSG  
Sbjct: 233  PPSGSGGGSSNSGGGSGSQSGSSGSG---SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGS 289

Query: 2603 YGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGH-------GRQGSGSGQS 2652
             G  G   G S      GSS+GSSS  G HG GS   +GH       G +  GSG+S
Sbjct: 290  SGNSGGSRGDSGSESSWGSSTGSSS--GNHG-GSGGGNGHKPGCEKPGNEARGSGES 343



 Score = 98.6 bits (244), Expect = 8e-20
 Identities = 103/370 (27%), Positives = 140/370 (37%), Gaps = 53/370 (14%)

Query: 1836 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 1895
            GSG       G+  +G+    + G HG G   S G G       ++ G    G+     S
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68

Query: 1896 SYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1955
                 G+R    + G +     G++ + G     +  +LG+  H  G     +    RHG
Sbjct: 69   EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124

Query: 1956 SGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST 2015
            + + + S  G  G    W +S G    GS    GLG            GQ   + G   T
Sbjct: 125  ADAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------------GQGQGNPGGLGT 170

Query: 2016 HGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2075
               HG     + S G +     Q +  GQ G+G   + G   QG+ +   PG+G   + +
Sbjct: 171  PWVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASN 224

Query: 2076 RQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2135
            +         SGSG  SS+   G G           S SG S S S   + +G SSG   
Sbjct: 225  QNEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSS 273

Query: 2136 HGSRSGQSSRGERHGSSSGSSSRYGQHGSGS-------RQSSGHGRQGSGSGHSP---SR 2185
             GS SG SS G   GSS  S    G  GS S         S  HG  G G+GH P     
Sbjct: 274  SGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP 333

Query: 2186 GRHGSGSGHS 2195
            G    GSG S
Sbjct: 334  GNEARGSGES 343



 Score = 98.2 bits (243), Expect = 1e-19
 Identities = 101/373 (27%), Positives = 143/373 (38%), Gaps = 35/373 (9%)

Query: 1576 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ-SPSYGRHGSGSGRSSSSGQHGSGLGES 1634
            G      SG    G+  G++ GHG   + S     + G+   G+  S  S   G G  E+
Sbjct: 19   GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78

Query: 1635 SGFGHHESSS-GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQ-- 1691
             G G  +    G + +       + H+ G   H     Q+    RHG+ +   S  G   
Sbjct: 79   VGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGVPG 137

Query: 1692 HGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHS 1751
            H      S GHG  GS  G       +  GLG    HG  G+ +G S    P  +  G  
Sbjct: 138  HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG-SFGMNPQGAPWGQG 196

Query: 1752 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ-------HGSTSGQSSTFDQEGSSTGQSS 1804
               G    G+    A +Q G GS    +Q +        GS  G S++    GS +G S 
Sbjct: 197  GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG 256

Query: 1805 SHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSS-SYGQHGSGSGWSSSSGRHGS 1863
            S G +G  ++ SSS G     S    S G  G  SG+S  S G  GS S W SS+G    
Sbjct: 257  S-GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG---- 311

Query: 1864 GSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRS-GQSSRGEQHGSSSGSSSS 1922
                 S  G+H  S          G G+GH    E+ G+ + G    G Q+  +S    +
Sbjct: 312  -----SSSGNHGGS----------GGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFN 356

Query: 1923 YGQHGSGSRQSLG 1935
            +       +  LG
Sbjct: 357  FDTFWKNFKSKLG 369



 Score = 95.9 bits (237), Expect = 5e-19
 Identities = 92/333 (27%), Positives = 127/333 (38%), Gaps = 22/333 (6%)

Query: 1106 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ-SPSYGRHGSGSGRSSSSGQHGSGLGES 1164
            G      SG    G+  G++ GHG   + S     + G+   G+  S  S   G G  E+
Sbjct: 19   GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78

Query: 1165 SGFGHHESSS-GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQ-- 1221
             G G  +    G + +       + H+ G   H     Q+    RHG+ +   S  G   
Sbjct: 79   VGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGVPG 137

Query: 1222 HGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHS 1281
            H      S GHG  GS  G       +  GLG    HG  G+ +G S    P  +  G  
Sbjct: 138  HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG-SFGMNPQGAPWGQG 196

Query: 1282 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ-------HGSTSGQSSTFDQEGSSTGQSS 1334
               G    G+    A +Q G GS    +Q +        GS  G S++    GS +G S 
Sbjct: 197  GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG 256

Query: 1335 SYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 1394
            S  +  + +  SSG    G+ SG S      GS      S G  GS S W SS+G     
Sbjct: 257  SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGN 316

Query: 1395 SGQSSGFGHHESSSWQSSGCTQHGS---GSGHS 1424
             G S G   H+       GC + G+   GSG S
Sbjct: 317  HGGSGGGNGHK------PGCEKPGNEARGSGES 343



 Score = 95.5 bits (236), Expect = 7e-19
 Identities = 106/376 (28%), Positives = 143/376 (38%), Gaps = 52/376 (13%)

Query: 1366 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSS 1425
            GSG       G+  +G+    + G HG G   S G G       ++ G    G+     S
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68

Query: 1426 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1485
                 G+R    + G R     G++ + G     +  +LG+  H  G     +    RHG
Sbjct: 69   EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124

Query: 1486 SGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSST 1545
            + + + S     G    W +S G    GS    GLG            GQ   + G   T
Sbjct: 125  ADAVRGSWQGVPGHNGAWETSGGHGIFGSQ--GGLG------------GQGQGNPGGLGT 170

Query: 1546 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 1605
               HG     + S G +     Q +  GQ G+G   + G   QG+ +   PG+G   + +
Sbjct: 171  PWVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASN 224

Query: 1606 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 1665
            +         SGSG  SS+   GSG           S SG S S S   + +G SSG   
Sbjct: 225  QNEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSS 273

Query: 1666 HGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHS 1725
             GS SG SS G   GSS  S    G  GS   +SS     GS SG   + G  G G GH 
Sbjct: 274  SGSSSGGSSGGSSGGSSGNSGGSRGDSGS---ESSWGSSTGSSSG---NHGGSGGGNGHK 327

Query: 1726 ---SSHGQHGSGSGRS 1738
                  G    GSG S
Sbjct: 328  PGCEKPGNEARGSGES 343



 Score = 95.1 bits (235), Expect = 9e-19
 Identities = 100/341 (29%), Positives = 146/341 (42%), Gaps = 46/341 (13%)

Query: 2493 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG--YGRQGSGSGQSPGHGQRGSGSRQSPS 2550
            SG+ S+    G + G++  HG  G   S+  G   G++  G+  S      G G+R++  
Sbjct: 26   SGEEST----GTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVG 80

Query: 2551 YG-RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS---------GH- 2599
             G R   G G + + G        + G   HE    Q+    +HG+ +         GH 
Sbjct: 81   TGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIRHGADAVRGSWQGVPGHN 139

Query: 2600 -----SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPS 2654
                 S G+G  GS+ G   +G+ +    G+   +G  G+ S  S G   QG+  GQ  +
Sbjct: 140  GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-SAGSFGMNPQGAPWGQGGN 198

Query: 2655 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGS 2714
             G    G     +  Q G GS R+S++        +        SGSG  S+ S  GSGS
Sbjct: 199  GGPPNFGTNTQGAVAQPGYGSVRASNQ--------NEGCTNPPPSGSGGGSSNSGGGSGS 250

Query: 2715 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSG--YGRHGAGSGQSLSH 2772
                   Q GS+   S+  +  GSS+G SSS    G  S  SSG   G  G   G S S 
Sbjct: 251  -------QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303

Query: 2773 GRHGSGSGQSS-SYGQHGSGSGQSSGYSQHGS---GSGQDG 2809
               GS +G SS ++G  G G+G   G  + G+   GSG+ G
Sbjct: 304  SSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESG 344



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 103/374 (27%), Positives = 141/374 (37%), Gaps = 49/374 (13%)

Query: 897  GSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSS 956
            GSG       G   +G+    + G HG G   S G G   + G+ +G    G+     S 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG--KAIGKEAG----GAAGSKVSE 69

Query: 957  YEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGS 1016
                G+R    +   Q     G++ + G     +  +LG+  H  G     +    RHG+
Sbjct: 70   ALGQGTREAVGTGVRQV-PGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHGA 125

Query: 1017 GSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 1076
             + + S  G       W +S G    GS    GLG            GQ   + G   T 
Sbjct: 126  DAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------------GQGQGNPGGLGTP 171

Query: 1077 GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 1136
              HG     + S G +     Q +  GQ G+G   + G   QG+ +   PG+G   + ++
Sbjct: 172  WVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASNQ 225

Query: 1137 QSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQH 1196
                     SGSG  SS+   GSG           S SG S S S   + +G SSG    
Sbjct: 226  NEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSSS 274

Query: 1197 GSRSGQSSRGERHGSSSGSSSHYGQHGSGS-------RQSSGHGRQGSGSGHSPSRGRHG 1249
            GS SG SS G   GSS  S    G  GS S         S  HG  G G+GH P   + G
Sbjct: 275  GSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG 334

Query: 1250 SGLGHSSSHGQHGS 1263
            +    S   G   S
Sbjct: 335  NEARGSGESGIQNS 348



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 97/339 (28%), Positives = 133/339 (39%), Gaps = 17/339 (5%)

Query: 2046 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ-SPSYGRHGSGSGRSSSSGQHGPGLGES 2104
            G      SG    G+  G++ GHG   + S     + G+   G+  S  S   G G  E+
Sbjct: 19   GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78

Query: 2105 SGFGHHESSS-GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQ-- 2161
             G G  +    G + +       + H+ G   H     Q+    RHG+ +   S  G   
Sbjct: 79   VGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGVPG 137

Query: 2162 HGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHS 2221
            H      S GHG  GS  G       +  G G    HG  G+ +G S    P  +  G  
Sbjct: 138  HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG-SFGMNPQGAPWGQG 196

Query: 2222 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ-------HGSTSGQSSTFDQEGSSTGQSS 2274
               G    G+    A +Q G GS    +Q +        GS  G S++    GS +G S 
Sbjct: 197  GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG 256

Query: 2275 SHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSS-SYGQHGSGSGWSSSSGRHGS 2333
            S G +G  ++ SSS G     S    S G  G  SG+S  S G  GS S W SS+G   S
Sbjct: 257  S-GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG-SSS 314

Query: 2334 GSGQSSGFGHHESSSWQSSGYTQHGSG-SGHSSSYEQHG 2371
            G+   SG G+      +  G    GSG SG  +S    G
Sbjct: 315  GNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353



 Score = 93.6 bits (231), Expect = 3e-18
 Identities = 108/355 (30%), Positives = 144/355 (40%), Gaps = 31/355 (8%)

Query: 484 GSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSP 543
           GSG + G  Q G  S  ++ GE  G   G + S G   +  +++ G     +GS  S + 
Sbjct: 17  GSGEA-GPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGG----AAGSKVSEAL 71

Query: 544 SRGRHES---GSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQES-RSGQSSGYGQ 599
            +G  E+   G RQ   +G       R          +GH  G   ++  R G  +  G 
Sbjct: 72  GQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131

Query: 600 HGSSSGHSS---THGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQ--QGS 654
                GH+    T G HG    Q    GQ     G   +   HG   + +  +G   QG+
Sbjct: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGA 191

Query: 655 GSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYS 714
             GQ  + G          +  Q G GS  +S+     +    S   G  S SG  SG S
Sbjct: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG-S 250

Query: 715 QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGH 774
           Q GS  S S+G   +GS SG        GSSSG SSS G  G  S  SSG+   G   G 
Sbjct: 251 QSGSSGSGSNGDNNNGSSSG--------GSSSG-SSSGGSSGGSSGGSSGN--SGGSRGD 299

Query: 775 SPSRVRHGSSSGHSS-SHGQHGSGTSCSSSC---GHYESGSGQASGFGQHESGSG 825
           S S    GSS+G SS +HG  G G      C   G+   GSG+ SG    E+  G
Sbjct: 300 SGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE-SGIQNSETSPG 353



 Score = 92.4 bits (228), Expect = 6e-18
 Identities = 106/385 (27%), Positives = 148/385 (38%), Gaps = 57/385 (14%)

Query: 1706 GSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 1765
            GSG       G   +G     + G HG G   S   G            G+   G+  S 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66

Query: 1766 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 1825
                 G G+      G        ++  D  G+  G+++    H  G++     G+Q   
Sbjct: 67   VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAA----HALGNT-GHEIGRQAED 119

Query: 1826 ---SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 1882
                G    RG      GH+ ++   G    + S  G  G G G   G G    + W   
Sbjct: 120  VIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVH- 174

Query: 1883 GYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 1942
            GY  + +GS         G+  GQ   G      + +  +  Q G GS ++    +  + 
Sbjct: 175  GYPGNSAGS---FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT- 230

Query: 1943 SGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2002
               +P PS    GSG G S+S G  GS SG         SGSG +      ++ +G SSG
Sbjct: 231  ---NPPPS----GSGGGSSNSGGGSGSQSG--------SSGSGSNG-----DNNNGSSSG 270

Query: 2003 YGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSG 2061
                GSSSG SS     G +SG SS  G  G S G S S    GS +  SSG +G  G G
Sbjct: 271  GSSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGG 323

Query: 2062 SGQSPGHGQRGSGSRQSPSYGRHGS 2086
            +G  PG  + G+ +R S   G   S
Sbjct: 324  NGHKPGCEKPGNEARGSGESGIQNS 348



 Score = 91.7 bits (226), Expect = 1e-17
 Identities = 107/384 (27%), Positives = 149/384 (38%), Gaps = 55/384 (14%)

Query: 1236 GSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 1295
            GSG       G   +G     + G HG G   S   G            G+   G+  S 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66

Query: 1296 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS-SYGHRGSG-SSQSSGYGRHG 1353
                 G G+      G        ++  D  G+  G+++ + G+ G     Q+    RHG
Sbjct: 67   VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAAHALGNTGHEIGRQAEDVIRHG 124

Query: 1354 AGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 1413
            A +     RG      GH+ ++   G    + S  G  G G G   G G    + W    
Sbjct: 125  ADA----VRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVHG- 175

Query: 1414 CTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1473
               +   S  S      G+  GQ   G      + +  +  Q G GS ++    +  +  
Sbjct: 176  ---YPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT-- 230

Query: 1474 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGY 1533
              +P PS    GSG G S+S    G GSG        +SGSS S   G  ++ +G SSG 
Sbjct: 231  --NPPPS----GSGGGSSNS----GGGSG-------SQSGSSGSGSNG--DNNNGSSSGG 271

Query: 1534 GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSGS 1592
               GSSSG SS     G +SG SS  G  G S G S S    GS +  SSG +G  G G+
Sbjct: 272  SSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGN 324

Query: 1593 GQSPGHGQRGSGSRQSPSYGRHGS 1616
            G  PG  + G+ +R S   G   S
Sbjct: 325  GHKPGCEKPGNEARGSGESGIQNS 348



 Score = 91.7 bits (226), Expect = 1e-17
 Identities = 106/379 (27%), Positives = 150/379 (39%), Gaps = 74/379 (19%)

Query: 365 GSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSP 424
           GSG       G+  + +    + G HG     S   G+           G+ + G+  S 
Sbjct: 17  GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGK---------AIGKEAGGAAGSK 66

Query: 425 GHGQRGSGSGQSPSSG-QHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGS 483
                G G+ ++  +G +   GFG + + G  V  + ++ G   HE   + +    +HG+
Sbjct: 67  VSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQ-AEDVIRHGA 125

Query: 484 GS---------GH------SSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSL 528
            +         GH      S GHG  GS+ G   +G+      G+   +G  G+ S  S 
Sbjct: 126 DAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-SAGSF 184

Query: 529 GHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRG-----PYESGSGHSSG 583
           G +  G+  GQ  +   G    G+    +    GYGS R+S++      P  SGSG  S 
Sbjct: 185 GMNPQGAPWGQGGNG--GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS- 241

Query: 584 LGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGS 643
                S SG  SG  Q GSS   S+    +GS+SG SSS    G++SG SS         
Sbjct: 242 -----SNSGGGSG-SQSGSSGSGSNGDNNNGSSSGGSSS----GSSSGGSSG-------- 283

Query: 644 SQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNG-PHGSVSGQSSGFG 702
                 G  G  SG S              S G  GS S W SS G   G+  G   G G
Sbjct: 284 ------GSSGGSSGNS------------GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNG 325

Query: 703 HKSGSGQSSGYSQHGSGSS 721
           HK G  +  G    GSG S
Sbjct: 326 HKPGC-EKPGNEARGSGES 343



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 104/378 (27%), Positives = 142/378 (37%), Gaps = 59/378 (15%)

Query: 782  GSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQ 841
            GS        G+  +GT+   + GH   G G A   G    G   G  + G A+G   S+
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALGH---GLGDALSEGV---GKAIG-KEAGGAAGSKVSE 69

Query: 842  GRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSG 901
                 T     +  +     G + + G     + HA G   H  G               
Sbjct: 70   ALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-------------- 115

Query: 902  QSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHG 961
            Q+    RHG+ + R S  G  G      +  GH    G   G    G G+          
Sbjct: 116  QAEDVIRHGADAVRGSWQGVPGHNGAWETSGGH-GIFGSQGGLGGQGQGN---------- 164

Query: 962  SRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQS 1021
               G       HG    S+ S+G +  G+      GQ G+G      P+ G +  G+   
Sbjct: 165  --PGGLGTPWVHGYPGNSAGSFGMNPQGAPW----GQGGNGG----PPNFGTNTQGAVAQ 214

Query: 1022 SSYGPYRSGSGWSSSRGPYESGSGHSS-----GLGHRESRSGQ-SSGYGQHGSSSGHSST 1075
              YG  R+ +       P  SGSG  S     G G +   SG  S+G   +GSSSG SS+
Sbjct: 215  PGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSS 274

Query: 1076 HGQHGSTSGQSS------SCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSGSGQSPGH 1128
                GS+SG SS      S G  G S G S S    GS +  SSG +G  G G+G  PG 
Sbjct: 275  ----GSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGC 330

Query: 1129 GQRGSGSRQSPSYGRHGS 1146
             + G+ +R S   G   S
Sbjct: 331  EKPGNEARGSGESGIQNS 348



 Score = 90.9 bits (224), Expect = 2e-17
 Identities = 105/385 (27%), Positives = 148/385 (38%), Gaps = 57/385 (14%)

Query: 2176 GSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 2235
            GSG       G   +G+    + G HG G   S   G            G+   G+  S 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66

Query: 2236 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 2295
                 G G+      G        ++  D  G+  G+++    H  G++     G+Q   
Sbjct: 67   VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAA----HALGNT-GHEIGRQAED 119

Query: 2296 ---SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 2352
                G    RG      GH+ ++   G    + S  G  G G G   G G    + W   
Sbjct: 120  VIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVH- 174

Query: 2353 GYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 2412
            GY  + +GS         G+  GQ   G      + +  +  Q G GS ++    +  + 
Sbjct: 175  GYPGNSAGS---FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT- 230

Query: 2413 SGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2472
               +P PS    GSG G S+S    G GSG         S SG S    + ++ +G SSG
Sbjct: 231  ---NPPPS----GSGGGSSNS----GGGSG---------SQSGSSGSGSNGDNNNGSSSG 270

Query: 2473 YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSG 2531
                GSSSG SS     G +SG SS  G  G S G S S    GS +  SSG +G  G G
Sbjct: 271  GSSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGG 323

Query: 2532 SGQSPGHGQRGSGSRQSPSYGRHGS 2556
            +G  PG  + G+ +R S   G   S
Sbjct: 324  NGHKPGCEKPGNEARGSGESGIQNS 348



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 106/377 (28%), Positives = 155/377 (41%), Gaps = 58/377 (15%)

Query: 196 GSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSS 255
           GSG       G+  +G+    +   HG G   S G  +   + G+ +G +   +GS  S 
Sbjct: 17  GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGK---AIGKEAGGA---AGSKVSE 69

Query: 256 GYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSG 315
             GQ G+R    + G R     G++ + G     +  +LG+     G RQ+   +RHG+ 
Sbjct: 70  ALGQ-GTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIG-RQAEDVIRHGAD 126

Query: 316 SGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQG 375
           +   S  G  G   ++  S GH   GS         + G G        G G G+    G
Sbjct: 127 AVRGSWQGVPGHNGAWETSGGHGIFGS---------QGGLG--------GQGQGNPGGLG 169

Query: 376 Q---HGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQ---- 428
               HG     A S G +     Q + +GQ  +    + G   ++ G+   PG+G     
Sbjct: 170 TPWVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGT--NTQGAVAQPGYGSVRAS 223

Query: 429 -RGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGH 487
            +  G    P SG  G   G S+S G   S SG S    + ++++  SSG +  GS SG 
Sbjct: 224 NQNEGCTNPPPSGSGG---GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG 280

Query: 488 SSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLG-HSRHGSGSGQSP----- 541
           SSG G  G  SG S      G S G S S    GS +  S G H   G G+G  P     
Sbjct: 281 SSG-GSSGGSSGNS------GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP 333

Query: 542 -SPSRGRHESGSRQSSS 557
            + +RG  ESG + S +
Sbjct: 334 GNEARGSGESGIQNSET 350



 Score = 90.1 bits (222), Expect = 3e-17
 Identities = 106/375 (28%), Positives = 141/375 (37%), Gaps = 61/375 (16%)

Query: 682  SGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQ 741
            SG  S+    G   G   G     G G++ G    G+  S  S     G+R    +   Q
Sbjct: 26   SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85

Query: 742  ---HGSSSGLSSSYGQ--HGSGSHQSSGH--GRQGSGSGHSPSRVRHGSSSGHSSSHGQH 794
                G++  L +  G+  H  G+   +GH  GRQ          +RHG+ +   S  G  
Sbjct: 86   VPGFGAADALGNRVGEAAHALGN---TGHEIGRQAEDV------IRHGADAVRGSWQGVP 136

Query: 795  GSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSS 854
            G   +  +S GH   GS    G      G GQG        G   +   HG     + S 
Sbjct: 137  GHNGAWETSGGHGIFGSQGGLG------GQGQGNP------GGLGTPWVHGYPGNSAGSF 184

Query: 855  GQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSG 914
            G +     Q + +GQ                G+G  P  G    G+   P YG   + + 
Sbjct: 185  GMNP----QGAPWGQ---------------GGNGGPPNFGTNTQGAVAQPGYGSVRASNQ 225

Query: 915  RSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHG 974
                +    SGSG     G  S+SG  SG     SGSG +       S  G SS S   G
Sbjct: 226  NEGCTNPPPSGSG-----GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG 280

Query: 975  SSSGSSSSYGQHGSGSRQSLGHGQHGSGS--GQSPSPSRGRHGSGSGQSSSYGPYRSGSG 1032
            SS GSS     +  GSR     G  GS S  G S   S G HG GSG  + + P     G
Sbjct: 281  SSGGSSGGSSGNSGGSR-----GDSGSESSWGSSTGSSSGNHG-GSGGGNGHKPGCEKPG 334

Query: 1033 WSSSRGPYESGSGHS 1047
             + +RG  ESG  +S
Sbjct: 335  -NEARGSGESGIQNS 348



 Score = 88.6 bits (218), Expect = 8e-17
 Identities = 93/314 (29%), Positives = 123/314 (39%), Gaps = 14/314 (4%)

Query: 2516 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ-SPSYGRHGSGSGRSSSSGQHGSGLGES 2574
            G      SG    G+  G++ GHG   + S     + G+   G+  S  S   G G  E+
Sbjct: 19   GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78

Query: 2575 SGFGHHESSS-GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQ-- 2631
             G G  +    G + +       + H+ G   H     Q+    RHG+ +   S  G   
Sbjct: 79   VGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGVPG 137

Query: 2632 HGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHS 2691
            H      S GHG  GS  G       +  GLG    HG  G+ +G S    P  +  G  
Sbjct: 138  HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG-SFGMNPQGAPWGQG 196

Query: 2692 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGS 2751
               G    G+    A +Q G GS    +Q + G T+   S     GS  G S+S G  GS
Sbjct: 197  GNGGPPNFGTNTQGAVAQPGYGSVRASNQNE-GCTNPPPS-----GSGGGSSNSGGGSGS 250

Query: 2752 GSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYS 2811
             S  SSG G +G  +  S S G     S   SS G  G  SG S G S+  SGS     S
Sbjct: 251  QSG-SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG-SRGDSGSESSWGS 308

Query: 2812 YCKGGSNHDGGSSG 2825
                 S + GGS G
Sbjct: 309  STGSSSGNHGGSGG 322



 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 91/346 (26%), Positives = 134/346 (38%), Gaps = 35/346 (10%)

Query: 878  SGRGRHGSGSGQSPGHGQRGSGS-GQSPSYGRHGSGSGRSSSSGRHGSGSGQS------- 929
            SG    G+  G++ GHG   + S G   + G+   G+  S  S   G G+ ++       
Sbjct: 26   SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85

Query: 930  -SGFGHKSSSGQSSGYTQHGSGS-GHSSSYE-----QHGSRSGQSSRSEQHGSSSGSSSS 982
              GFG   + G   G   H  G+ GH    +     +HG+ + + S     G +    +S
Sbjct: 86   VPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETS 145

Query: 983  YGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYES 1042
             G    GS+  LG    G+  G       G  G+ +G   S+G    G+ W       + 
Sbjct: 146  GGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG---SFGMNPQGAPWG------QG 196

Query: 1043 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH 1102
            G+G     G     +    GYG   +S+ +       G T+   S  G   ++SG  S  
Sbjct: 197  GNGGPPNFGTNTQGAVAQPGYGSVRASNQNE------GCTNPPPSGSGGGSSNSGGGSG- 249

Query: 1103 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRG--SGSRQSPSYGRHGSGSGRSSSSGQHGSG 1160
             Q GS  S S+G    GS SG S      G  SG     S G  G   G S S    GS 
Sbjct: 250  SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSS 309

Query: 1161 LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 1206
             G SS  G+H  S G +            + G G+ G ++ ++S G
Sbjct: 310  TGSSS--GNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353



 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 99/362 (27%), Positives = 140/362 (38%), Gaps = 37/362 (10%)

Query: 1340 GSGSSQSSGYGRHGAGSGQSPSRGRHGSGS----GHSSSYGQHGSGSGWSSSSGRHGSGS 1395
            GSG +     G    G+    + G HG G     G   + G+   G+  S  S   G G+
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75

Query: 1396 GQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSS--GSSSSY 1453
             ++ G G  +   + ++    +  G    +          Q+    RHG+ +  GS    
Sbjct: 76   REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135

Query: 1454 GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESG 1513
              H      S GHG  GS  G          G G G     +P G G+ W      Y   
Sbjct: 136  PGHNGAWETSGGHGIFGSQGGLG--------GQGQG-----NPGGLGTPWVHG---YPGN 179

Query: 1514 SSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHG 1573
            S+ S G+  + +  GQ    G     +       Q G  S ++S+  + G ++   S  G
Sbjct: 180  SAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE-GCTNPPPSGSG 238

Query: 1574 QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGE 1633
              G  S+   G G Q SGS  S  +G   +GS         GS SG SSS G  G   G 
Sbjct: 239  --GGSSNSGGGSGSQ-SGSSGSGSNGDNNNGSSSG------GSSSG-SSSGGSSGGSSGG 288

Query: 1634 SSGFGHHESSSGQSSSYSQHGSGSGHSSG-YGQHGSRSGQSSRGERHGSSSRSSSRYGQH 1692
            SS  G+   S G S S S  GS +G SSG +G  G  +G     E+ G+ +R S   G  
Sbjct: 289  SS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ 346

Query: 1693 GS 1694
             S
Sbjct: 347  NS 348



 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 93/336 (27%), Positives = 139/336 (41%), Gaps = 38/336 (11%)

Query: 1083 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG--YGRQGSGSGQSPGHGQRGSGSRQSPS 1140
            SG+ S+    G + G++  HG  G   S+  G   G++  G+  S      G G+R++  
Sbjct: 26   SGEEST----GTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVG 80

Query: 1141 YG-RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS---------GH- 1189
             G R   G G + + G        + G   HE    Q+    +HG+ +         GH 
Sbjct: 81   TGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIRHGADAVRGSWQGVPGHN 139

Query: 1190 -----SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPS 1244
                 S G+G  GS+ G   +G+ +    G+   +G  G+ S  S G   QG+  G   +
Sbjct: 140  GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-SAGSFGMNPQGAPWGQGGN 198

Query: 1245 RGRHGSGLGHSSSHGQHGSGSGRSSSRG-------PYESRSGHSSVFGQHESGSGHSSAY 1297
             G    G     +  Q G GS R+S++        P  S  G S+  G   S SG S + 
Sbjct: 199  GGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSG 258

Query: 1298 SQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSG 1357
            S   + +G        GS+SG SS     GSS    +S G RG   S+SS     G+ SG
Sbjct: 259  SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSS---GNSGGSRGDSGSESSWGSSTGSSSG 315

Query: 1358 QSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS 1393
               + G  G G+GH     + G+ +  S  SG   S
Sbjct: 316  ---NHGGSGGGNGHKPGCEKPGNEARGSGESGIQNS 348



 Score = 83.6 bits (205), Expect = 3e-15
 Identities = 98/362 (27%), Positives = 141/362 (38%), Gaps = 37/362 (10%)

Query: 2280 GSGSSQSSSYGQQGSGSGQSPSRGRHGSGS----GHSSSYGQHGSGSGWSSSSGRHGSGS 2335
            GSG +     G++ +G+    + G HG G     G   + G+   G+  S  S   G G+
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75

Query: 2336 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSS--GSSSSY 2393
             ++ G G  +   + ++    +  G    +          Q+    RHG+ +  GS    
Sbjct: 76   REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135

Query: 2394 GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESG 2453
              H      S GHG  GS  G          G G G     +P G G+ W      Y   
Sbjct: 136  PGHNGAWETSGGHGIFGSQGGLG--------GQGQG-----NPGGLGTPWVHG---YPGN 179

Query: 2454 SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHG 2513
            S  S G+  + +  GQ    G     +       Q G  S ++S+  + G ++   S  G
Sbjct: 180  SAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE-GCTNPPPSGSG 238

Query: 2514 QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGE 2573
              G  S+   G G Q SGS  S  +G   +GS         GS SG SSS G  G   G 
Sbjct: 239  --GGSSNSGGGSGSQ-SGSSGSGSNGDNNNGSSSG------GSSSG-SSSGGSSGGSSGG 288

Query: 2574 SSGFGHHESSSGQSSSYSQHGSGSGHSSG-YGQHGSRSGQSSRGERHGSSSGSSSHYGQH 2632
            SS  G+   S G S S S  GS +G SSG +G  G  +G     E+ G+ +  S   G  
Sbjct: 289  SS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ 346

Query: 2633 GS 2634
             S
Sbjct: 347  NS 348



 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 75/280 (26%), Positives = 112/280 (40%), Gaps = 29/280 (10%)

Query: 180 GEQNSDSHQSSGRGQCGSGSGQSPNYGQH---GSGSGQSS---SNDTHGSGSGQSSGFSQ 233
           G + S++     R   G+G  Q P +G     G+  G+++    N  H  G  Q+    +
Sbjct: 64  GSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIR 122

Query: 234 HKSSS--GQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGS------------ 279
           H + +  G   G   H      S G+G  GS+ G   +G+ +    G+            
Sbjct: 123 HGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG 182

Query: 280 -------SSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYS 332
                   + +GQ G+G   + G   QG+ ++     VR  + +   ++    GSG   S
Sbjct: 183 SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242

Query: 333 YSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGS 392
            S G   S SG +      ++ +G SSG S  GS SG SS     GS+     S G  GS
Sbjct: 243 NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGS 302

Query: 393 SSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSG 432
            S   SS G        S G   H  G  + PG+  RGSG
Sbjct: 303 ESSWGSSTGSSSGNHGGSGGGNGHKPGC-EKPGNEARGSG 341



 Score = 82.4 bits (202), Expect = 6e-15
 Identities = 94/360 (26%), Positives = 139/360 (38%), Gaps = 41/360 (11%)

Query: 1810 GSGSSQSSSYGQQGSGSGQSPSRGRHGSGS----GHSSSYGQHGSGSGWSSSSGRHGSGS 1865
            GSG +     G++ +G+    + G HG G     G   + G+   G+  S  S   G G+
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75

Query: 1866 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSS--GSSSSY 1923
             ++ G G  +   + ++    +  G    +          Q+    +HG+ +  GS    
Sbjct: 76   REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135

Query: 1924 GQHGSGSRQSLGHGQHGS-----GSGQSPSPSRGR---HGSGSGQSSSYGPYGSGSGWSS 1975
              H      S GHG  GS     G GQ      G    HG     + S+G    G+ W  
Sbjct: 136  PGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWG- 194

Query: 1976 SRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGAS 2035
                 + G+G     G     +    GYG   +S+ +        S SG  SS    G+ 
Sbjct: 195  -----QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249

Query: 2036 SGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSG 2095
            S       Q GS  S S+G    GS SG S       SGS    S G  GS  G S +SG
Sbjct: 250  S-------QSGSSGSGSNGDNNNGSSSGGS------SSGSSSGGSSG--GSSGGSSGNSG 294

Query: 2096 QHGPGLGESSGFGHHESSSGQSS-SYSQHGSGSGHSSGYGQHGSRS-GQSSRGERHGSSS 2153
                  G  S +G   SS+G SS ++   G G+GH  G  + G+ + G    G ++  +S
Sbjct: 295  GSRGDSGSESSWG---SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETS 351



 Score = 82.4 bits (202), Expect = 6e-15
 Identities = 100/384 (26%), Positives = 142/384 (36%), Gaps = 62/384 (16%)

Query: 490 GHGQHGS-RSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRH-----GSGSGQSPSP 543
           G G+ G  +SG+ S G   G + G       HG G   S G  +      G  +G   S 
Sbjct: 17  GSGEAGPLQSGEESTGTNIGEALG-------HGLGDALSEGVGKAIGKEAGGAAGSKVSE 69

Query: 544 SRGRHESGSRQSSSYGPHGY-GSGRSSSRGPYESGSGHSSG-LGHQESRSGQSSGYGQHG 601
           + G+   G+R++   G     G G + + G     + H+ G  GH+  R  Q+    +HG
Sbjct: 70  ALGQ---GTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR--QAEDVIRHG 124

Query: 602 SSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPS 661
           + +   S  G  G      +S              G HG   SQ    GQ     G   +
Sbjct: 125 ADAVRGSWQGVPGHNGAWETS--------------GGHGIFGSQGGLGGQGQGNPGGLGT 170

Query: 662 RGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKS-GSGQSSGYSQHGSGS 720
              HG     + S+G +  G+ W           GQ    G  + G+      +Q G GS
Sbjct: 171 PWVHGYPGNSAGSFGMNPQGAPW-----------GQGGNGGPPNFGTNTQGAVAQPGYGS 219

Query: 721 SHSSGYRKHGSR---SGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPS 777
             +S   +  +    SG    S   G  SG  S  G  GSGS+   G    GS SG    
Sbjct: 220 VRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQS--GSSGSGSN---GDNNNGSSSG---- 270

Query: 778 RVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGH 837
               GSSSG SS     GS    S + G     SG  S +G     S   +   G  +GH
Sbjct: 271 ----GSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGH 326

Query: 838 FSSQGRHGSTSGQSSSSGQHDSSS 861
                + G+ +  S  SG  +S +
Sbjct: 327 KPGCEKPGNEARGSGESGIQNSET 350



 Score = 82.0 bits (201), Expect = 8e-15
 Identities = 93/354 (26%), Positives = 130/354 (36%), Gaps = 31/354 (8%)

Query: 987  GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS-GQSSSYGPYRSGSGWSSSRGPYESGSG 1045
            GSG    L  G+  +G+    +   G   + S G   + G    G+  S        G+ 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76

Query: 1046 HSSGLGHRESRS-GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQ 1104
             + G G R+    G +   G     + H+  +  H     Q+    +HGA + + S  G 
Sbjct: 77   EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGV 135

Query: 1105 --HGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLG 1162
              H      S G+G  GS  G   G GQ   G   +P    +   S  S      G+  G
Sbjct: 136  PGHNGAWETSGGHGIFGSQGGLG-GQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWG 194

Query: 1163 ESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ-------HGSRSGQSSRGERHGSSSGS 1215
            +    G     +    + +Q G GS  +S   +        GS  G S+ G   GS SGS
Sbjct: 195  QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGS 254

Query: 1216 SSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYE 1275
            S      GSGS   +G    GS SG        GS  G SS     GS  G S + G   
Sbjct: 255  S------GSGS---NGDNNNGSSSG--------GSSSGSSSGGSSGGSSGGSSGNSGGSR 297

Query: 1276 SRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ-GQHGSTSGQSSTFDQEGS 1328
              SG  S +G     S  +   S  G+G    C + G     SG+S   + E S
Sbjct: 298  GDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETS 351



 Score = 80.9 bits (198), Expect = 2e-14
 Identities = 96/352 (27%), Positives = 136/352 (38%), Gaps = 45/352 (12%)

Query: 640 GSGSSQSSRYGQQGSGSGQSPSRGRHGSDF---GHSSSYGQHGSGSGWSSSNGPHGSVSG 696
           GSG +   + G++ +G+    + G    D    G   + G+   G+  S  +   G  + 
Sbjct: 17  GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76

Query: 697 QS--------SGFGHKSGSGQSSGYSQHGSGSS-HSSGYR-----KHGSRSGQSSRSEQH 742
           ++         GFG     G   G + H  G++ H  G +     +HG+ + + S     
Sbjct: 77  EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVP 136

Query: 743 GSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSS 802
           G +    +S G    GS    G   QG+  G     V HG     + S G +  G     
Sbjct: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWV-HGYPGNSAGSFGMNPQGAPWG- 194

Query: 803 SCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGR-------HGSTSGQSSSSG 855
                + G+G    FG +  G+    +Q G  S   S+Q          GS  G S+S G
Sbjct: 195 -----QGGNGGPPNFGTNTQGA---VAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246

Query: 856 QHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGS---- 911
              S SG S S    ++ +  +SG    GS SG S G    GS      S G  GS    
Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306

Query: 912 GSGRSSSSGRH-GSGSGQSSGFGHKSSSGQSSGYTQHGSG-SGHSSSYEQHG 961
           GS   SSSG H GSG G     GHK    +  G    GSG SG  +S    G
Sbjct: 307 GSSTGSSSGNHGGSGGGN----GHKPGC-EKPGNEARGSGESGIQNSETSPG 353



 Score = 74.7 bits (182), Expect = 1e-12
 Identities = 57/170 (33%), Positives = 74/170 (43%), Gaps = 16/170 (9%)

Query: 174 GQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQ-------HGSGSGQSSSNDTHGSGSG 226
           GQ  + G  N  ++      Q G GS ++ N  +        GSG G S+S    GS SG
Sbjct: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253

Query: 227 QSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQH 286
            S   S   +++G SSG S  GS SG SSG    GS  G S      R  SGS SS+G  
Sbjct: 254 SSGSGSNGDNNNGSSSGGSSSGSSSGGSSG----GSSGGSSGNSGGSRGDSGSESSWG-- 307

Query: 287 GSGSRQSLGHGRQGSGSRQSPSHVRHGS---GSGHSSSHGQHGSGSSYSY 333
            S    S  HG  G G+   P   + G+   GSG S       S   +++
Sbjct: 308 SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFNF 357



 Score = 73.2 bits (178), Expect = 4e-12
 Identities = 90/333 (27%), Positives = 130/333 (39%), Gaps = 55/333 (16%)

Query: 206 GQHGSGSGQSSSNDTHGSGSGQSSGFSQHK-------SSSGQSSGYSQHGSGS-GHSSGY 257
           G+   G+  S  ++  G G+ ++ G    +        + G   G + H  G+ GH  G 
Sbjct: 56  GKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR 115

Query: 258 G-----QHGSRSGQSSRGERHRSSSGSSSSYGQHGS-GSRQSLGHGRQGSGSRQSPSHVR 311
                 +HG+ + + S  +     +G+  + G HG  GS+  LG   QG+        V 
Sbjct: 116 QAEDVIRHGADAVRGS-WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWV- 173

Query: 312 HGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGY-----SKHGS 366
           HG     + S G +  G+ +       + G+G    FG +  G+    GY     S    
Sbjct: 174 HGYPGNSAGSFGMNPQGAPWG------QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE 227

Query: 367 GSGHSSSQGQHGSTSGQASSSG-QHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPG 425
           G  +    G  G +S     SG Q GSS   S S G + + S  SSG     S SG S G
Sbjct: 228 GCTNPPPSGSGGGSSNSGGGSGSQSGSSG--SGSNGDNNNGS--SSG----GSSSGSSSG 279

Query: 426 HGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGS 485
               GS  G   SSG  G   G S S   + S +G SSG                HG GS
Sbjct: 280 GSSGGSSGG---SSGNSGGSRGDSGSESSWGSSTGSSSG---------------NHG-GS 320

Query: 486 GHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYG 518
           G  +GH     + G  +RG  +     S +S G
Sbjct: 321 GGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353



 Score = 67.0 bits (162), Expect = 3e-10
 Identities = 87/331 (26%), Positives = 128/331 (38%), Gaps = 58/331 (17%)

Query: 81  LVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEE-----------NKRQESSFSH 129
           L +   K IGK+    +GSK+ +   Q   E   T   +           N+  E++  H
Sbjct: 47  LSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAA--H 104

Query: 130 SSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSY--SGQSSSYGEQNSDSH 187
           +  + G      R     ++ G +++  R S+Q    G + ++  SG    +G Q     
Sbjct: 105 ALGNTGHE--IGRQAEDVIRHGADAV--RGSWQ-GVPGHNGAWETSGGHGIFGSQGGLGG 159

Query: 188 QSSGR----------GQCGSGSG------QSPNYGQHGSGSGQSSSNDTHGSGSGQSSGF 231
           Q  G           G  G+ +G      Q   +GQ G+G   +   +T G+ +    G 
Sbjct: 160 QGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGS 219

Query: 232 SQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSR 291
            +  + +   +     GSG G S+  G  GS+SG S  G    +++GSSS     GS S 
Sbjct: 220 VRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSG 279

Query: 292 QSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQH 351
            S G G  G            GS      S G  GS SS+  S G   S SG   G G  
Sbjct: 280 GSSG-GSSG------------GSSGNSGGSRGDSGSESSWGSSTG---SSSGNHGGSG-- 321

Query: 352 ESGSGQSSGYSKHGS---GSGHSSSQGQHGS 379
             G+G   G  K G+   GSG S  Q    S
Sbjct: 322 -GGNGHKPGCEKPGNEARGSGESGIQNSETS 351



 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 53/166 (31%), Positives = 66/166 (39%), Gaps = 13/166 (7%)

Query: 132 WSAGEND---SYSRNVRGSL-KPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSH 187
           W  G N    ++  N +G++ +PG  S+  R S Q +  G  N     S   G  NS   
Sbjct: 193 WGQGGNGGPPNFGTNTQGAVAQPGYGSV--RASNQNE--GCTNPPPSGSGG-GSSNSGGG 247

Query: 188 QSSGRGQCGSGSGQSPNYGQH--GSGSGQSSSNDTHGSGSGQS--SGFSQHKSSSGQSSG 243
             S  G  GSGS    N G    GS SG SS   + GS  G S  SG S+  S S  S G
Sbjct: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG 307

Query: 244 YSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSG 289
            S   S   H    G +G + G    G   R S  S     +   G
Sbjct: 308 SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score =  104 bits (259), Expect = 1e-21
 Identities = 190/707 (26%), Positives = 257/707 (36%), Gaps = 122/707 (17%)

Query: 2059 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSS 2118
            GS S  SP +     G   +P      S SG            G++  F    S +  + 
Sbjct: 847  GSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTL 906

Query: 2119 SYSQHGSGSGHSSGYGQH-------------GSRSGQSSRGERHGSSSGSSSRYGQHGSG 2165
                 G  +G +   G +             G     +   E H  S G     G  G  
Sbjct: 907  GVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKE 966

Query: 2166 SRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHG---SGSGRSSSRGPYESRSGHSS 2222
              Q     ++G+G+ +S       SG G  S  G+     S  G+S  + P   ++    
Sbjct: 967  KTQK--RVKEGNGTSNSTL-----SGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEG 1019

Query: 2223 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSST--------FDQEGSSTGQSS 2274
                H S +   +  +  G GS    S G+  +  G ++           +     G+ S
Sbjct: 1020 KSPSHSSSNRPFTPPTSTG-GSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPS 1078

Query: 2275 SHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 2334
            SH Q+ S  S SSS    GS S  S           HSSS     S SG   SS   GS 
Sbjct: 1079 SHSQYTSSGSVSSS----GSKSHHS-----------HSSSSSSSASTSGKMKSSKSEGSS 1123

Query: 2335 SGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYG 2394
            S + S      SS + S G     SGS  S +  Q G + G SS   +HG SSGSSS+  
Sbjct: 1124 SSKLS------SSMYSSQG----SSGSSQSKNSSQSGGKPG-SSPITKHGLSSGSSSTK- 1171

Query: 2395 QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQ-SSSYSPYGSGSGWSSSRGPYESG 2453
                G   SL    + S S  + SPS  R   GS + +S   P       S ++ P  SG
Sbjct: 1172 MKPQGKPSSL---MNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSG 1228

Query: 2454 SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHG 2513
            SG S         SG SS  G   SSSG  S+      T   S+SC    ASS   SS  
Sbjct: 1229 SGGSH-------MSGTSSSSGMK-SSSGLGSSGSLSQKTPPSSNSCT---ASSSSFSS-- 1275

Query: 2514 QHGSGSSQSSGYGRQGSGSGQSPG---------------HGQRGSG-SRQSPSYGRHGSG 2557
               SGSS SS   + GS  G+SP                HG   SG   + P  G+ G  
Sbjct: 1276 ---SGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVS 1332

Query: 2558 SGRSS--SSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 2615
            +  SS   S +H    GE    G  E S    S  S  GS    S           ++S 
Sbjct: 1333 TNSSSHPMSSKHNMSGGEFQ--GKREKSDKDKSKVSTSGSSVDSSK----------KTSE 1380

Query: 2616 GERHGSSSGSSSHYGQHGSGS-----RQSSGHGRQGSGSGQSP---SRGRHGSGLGHSSS 2667
             +  GS+  +     +H  GS     + +     + SG G  P   S   +GS L  S S
Sbjct: 1381 SKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPL-ISGS 1439

Query: 2668 HGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGS 2714
              +H  GS   S    Y  +    ++  + ESGS  +    Q+   S
Sbjct: 1440 TPKHERGSPSHSKSPAYTPQ----NLDSESESGSSIAEKSYQNSPSS 1482



 Score =  101 bits (252), Expect = 9e-21
 Identities = 145/547 (26%), Positives = 201/547 (36%), Gaps = 70/547 (12%)

Query: 480  QHGSGS-GHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSG 538
            +H SGS G     G  G    Q    E  G+S  + S  G      ++S   S  G    
Sbjct: 948  EHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKD 1007

Query: 539  QSPSPSRGRHESGS-RQSSSYGPHGYGSGRSSSRGPYESGSGHSSG-------------L 584
            + P   +   E  S   SSS  P    +    S+ P  +G   +               +
Sbjct: 1008 KPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQI 1067

Query: 585  GHQESRSGQSSGYGQHGSS----SGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHG 640
                   G+ S + Q+ SS    S  S +H  H S+S  S+S      TSG+  S    G
Sbjct: 1068 PKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSAS------TSGKMKSSKSEG 1121

Query: 641  SGSSQ--SSRYGQQGS-GSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSN-GPHGSVSG 696
            S SS+  SS Y  QGS GS QS +  + G   G SS   +HG  SG SS+   P G  S 
Sbjct: 1122 SSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPG-SSPITKHGLSSGSSSTKMKPQGKPSS 1180

Query: 697  QSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHG 756
              +     S    S  +S+   GS   +   K    +  SS+++   S    S S G H 
Sbjct: 1181 LMN--PSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPIS----SGSGGSHM 1234

Query: 757  SGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASG 816
            SG+  SSG  +  SG G          SSG  S      S +  +SS     SGS  +S 
Sbjct: 1235 SGTSSSSGM-KSSSGLG----------SSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSS 1283

Query: 817  FGQHESGSGQGYSQHGSAS-GHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASH 875
              QH S  G+  S++   S      + +HG  +         D   G S++   H  +S 
Sbjct: 1284 QNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSK 1343

Query: 876  HASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSG-------RHGSGS-- 926
            H    G       +S     + S SG S    +  S S    S+G       +H  GS  
Sbjct: 1344 HNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPS 1403

Query: 927  ----------GQSSGFGHKSSSGQSSGYTQ---HGSGSGHSSSYEQHGSRSGQSSRSEQH 973
                      G+SSG G +     S  Y      GS   H      H      + ++   
Sbjct: 1404 IKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDS 1463

Query: 974  GSSSGSS 980
             S SGSS
Sbjct: 1464 ESESGSS 1470



 Score =  101 bits (252), Expect = 9e-21
 Identities = 138/449 (30%), Positives = 175/449 (38%), Gaps = 50/449 (11%)

Query: 189  SSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHG 248
            SS      SGS  S     H S S  SSS+    SG  +SS      SS   SS YS  G
Sbjct: 1078 SSHSQYTSSGSVSSSGSKSHHSHSS-SSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQG 1136

Query: 249  -SGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSS----YGQHGSGSRQSLGHGRQGSGS 303
             SGS  S    Q G + G SS   +H  SSGSSS+     G+  S    SL      S  
Sbjct: 1137 SSGSSQSKNSSQSGGKPG-SSPITKHGLSSGSSSTKMKPQGKPSSLMNPSL------SKP 1189

Query: 304  RQSPSHVRHGSGSGHSSSHGQHGSGS-SYSYSRGHYESGSGQTSGFGQHESGSGQSSGYS 362
              SPSH R   GS   +S  +   G+   S ++    SGSG     G H SG+  SSG  
Sbjct: 1190 NISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSG-----GSHMSGTSSSSG-M 1243

Query: 363  KHGSGSGHSSSQGQH---GSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSG 419
            K  SG G S S  Q     S S  ASSS    S S  SSS  QH S+   S  R +  S 
Sbjct: 1244 KSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSL 1303

Query: 420  SG--QSPGHGQRGSG-SGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSG--FGHHESSSEH 474
            +       HG   SG  G+ P  GQ   G   +SSS P  S    S G   G  E S + 
Sbjct: 1304 TAVIDKLKHGVVTSGPGGEDPLDGQ--MGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKD 1361

Query: 475  SSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGS-----RQSLG 529
             S  +  GS    S           ++S  +  GS+  +     +H  GS     + +L 
Sbjct: 1362 KSKVSTSGSSVDSSK----------KTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQ 1411

Query: 530  HSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPY-----ESGSGHSSGL 584
                 SG G  P  +  ++      S S   H  GS   S    Y     +S S   S +
Sbjct: 1412 KPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSI 1471

Query: 585  GHQESRSGQSSGYGQHGSSSGHSSTHGQH 613
              +  ++  SS  G        +  H +H
Sbjct: 1472 AEKSYQNSPSSDDGIRPLPEYSTEKHKKH 1500



 Score = 99.8 bits (247), Expect = 4e-20
 Identities = 168/677 (24%), Positives = 231/677 (34%), Gaps = 77/677 (11%)

Query: 565  SGRSSSRGP----YESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 620
            +G  SS  P    +  G   +  L + +S+SG    Y    S SG +       S +  +
Sbjct: 846  AGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNT 905

Query: 621  SSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGS 680
                  G  +G++   G + + +   S     G     +     H    G   + G  G 
Sbjct: 906  LGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGK 965

Query: 681  GSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSE 740
                      +G+ +   SG G  S  G+ S    +   S      RK     G   +S 
Sbjct: 966  EKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEG---KSP 1022

Query: 741  QHGSSSG-LSSSYGQHGSGSHQSSGHGRQGSGSGHSPS-----RVRHGSSS-GHSSSHGQ 793
             H SS+   +      GS S  S+G  +   G    P      ++  G+   G  SSH Q
Sbjct: 1023 SHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQ 1082

Query: 794  HGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSS 853
            + S  S SSS                            GS S H        S S  SSS
Sbjct: 1083 YTSSGSVSSS----------------------------GSKSHH--------SHSSSSSS 1106

Query: 854  SGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGS 913
            S         S S G   S    +    +  SGS QS    Q G   G SP   +HG  S
Sbjct: 1107 SASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSP-ITKHGLSS 1165

Query: 914  GRSSSSGR-HGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQ 972
            G SS+  +  G  S   +    K +   S      GS    S      G+     ++S  
Sbjct: 1166 GSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPI 1225

Query: 973  HGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSG 1032
               S GS  S     SG + S G G  GS S ++P  S     S S  SS      SGS 
Sbjct: 1226 SSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSS------SGSS 1279

Query: 1033 WSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHG----SSSGHSSTHGQHGSTSGQSSS 1088
             SSS+  + S  G S     + S +       +HG       G     GQ G ++  SS 
Sbjct: 1280 MSSSQNQHGSSKGKSPSRNKKPSLTAVIDKL-KHGVVTSGPGGEDPLDGQMGVSTNSSS- 1337

Query: 1089 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG------ 1142
               H  SS  + S G+      +S     + S SG S    ++ S S+   S G      
Sbjct: 1338 ---HPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIII 1394

Query: 1143 -RHGSGSGRSSSSGQHGSGLGESSGFG--HHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 1199
             +H  GS  S  +       GESSG G     +SS    S    GS   H  G   H   
Sbjct: 1395 SKHDGGS-PSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKS 1453

Query: 1200 SGQSSRGERHGSSSGSS 1216
               + +     S SGSS
Sbjct: 1454 PAYTPQNLDSESESGSS 1470



 Score = 97.4 bits (241), Expect = 2e-19
 Identities = 175/696 (25%), Positives = 241/696 (34%), Gaps = 83/696 (11%)

Query: 1385 SSSSGRHGSGSGQSSGF--GHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSG------- 1435
            SSSSG   S    S  F   ++E+     +      +GS  S S   H    G       
Sbjct: 810  SSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDL 869

Query: 1436 -----QSSRGERH---GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSG 1487
                 QS  GE +    S SG +  +    S +  +LG    G  +G++      +  + 
Sbjct: 870  LNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTV 929

Query: 1488 -----SGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGH 1542
                 S    + +P       S S+GP  +    +  LG  +++     G G   S+   
Sbjct: 930  DFSIISVAGKALAPADLMEHHSGSQGPLLT----TGDLGKEKTQKRVKEGNGTSNSTLSG 985

Query: 1543 SSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 1602
                 + G  S   S+ G+      +       G   S SS   R  +    + G    G
Sbjct: 986  PGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSS-NRPFTPPTSTGGSKSPG 1044

Query: 1603 SGSRQSPSYGRHGSGSGRSSSSGQHGSGL-GESSGFGHHESSSGQSSSYSQHGSGSGHSS 1661
            S  R     G       + +     G+ + G+ S    + SS   SSS S+  S   HSS
Sbjct: 1045 SAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSK--SHHSHSS 1102

Query: 1662 GYGQHGSRSGQ--SSRGERHGSSSRSSSRYGQHG-SGSRQSSGHGRQGSGSGQSPSRGRH 1718
                  S SG+  SS+ E   SS  SSS Y   G SGS QS    + G   G SP   +H
Sbjct: 1103 SSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPIT-KH 1161

Query: 1719 GSGLGHSS------------------------SHGQHGSGSGR-SSSRGPYESRSGHSSV 1753
            G   G SS                        SH +   GS + +S   P       S  
Sbjct: 1162 GLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKA 1221

Query: 1754 FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGS 1813
                 SGSG  S  S   S SG   S G   S S    T     S T  SSS     SGS
Sbjct: 1222 KSPISSGSG-GSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFS--SSGS 1278

Query: 1814 SQSSSYGQQGSGSGQSPSRGRHGSGSG--HSSSYGQHGSGSGWSSS-SGRHGSGSGQSSG 1870
            S SSS  Q GS  G+SPSR +  S +       +G   SG G      G+ G  +  SS 
Sbjct: 1279 SMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSS- 1337

Query: 1871 FGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGS 1930
              H  SS    SG      G       +    +S  S+ G    SS  +S S     +G 
Sbjct: 1338 --HPMSSKHNMSG------GEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGV 1389

Query: 1931 RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQ--------SSSYG-PYGSGSGWSSSRGPYE 1981
             + +     G         +  + G  SG+        S +YG P  SGS     RG   
Sbjct: 1390 AKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPS 1449

Query: 1982 SGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG 2017
                 +    + +S S   S   +    +  SS  G
Sbjct: 1450 HSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDG 1485



 Score = 96.7 bits (239), Expect = 3e-19
 Identities = 177/677 (26%), Positives = 243/677 (35%), Gaps = 97/677 (14%)

Query: 1589 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSS 1648
            GS S  SP +     G   +P      S SG         S  G++  F    S +  + 
Sbjct: 847  GSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTL 906

Query: 1649 SYSQHGSGSGHSSGYGQH-------------GSRSGQSSRGERHGSSSRSSSRYGQHGSG 1695
                 G  +G +   G +             G     +   E H  S       G  G  
Sbjct: 907  GVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKE 966

Query: 1696 SRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHG---SGSGRSSSRGPYESRSGHSS 1752
              Q     ++G+G+  S       SG G  S  G+     S  G+S  + P   ++    
Sbjct: 967  KTQK--RVKEGNGTSNSTL-----SGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEG 1019

Query: 1753 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSST--------FDQEGSSTGQSS 1804
                H S +   +  +  G GS    S G+  +  G ++           +     G+ S
Sbjct: 1020 KSPSHSSSNRPFTPPTSTG-GSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPS 1078

Query: 1805 SHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 1864
            SH Q          Y   GS S  S S+  H     HSSS     S SG   SS   GS 
Sbjct: 1079 SHSQ----------YTSSGSVS-SSGSKSHH----SHSSSSSSSASTSGKMKSSKSEGSS 1123

Query: 1865 SGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYG 1924
            S + S      SS + S G     SGS  S +  Q G + G SS   +HG SSGSSS+  
Sbjct: 1124 SSKLS------SSMYSSQG----SSGSSQSKNSSQSGGKPG-SSPITKHGLSSGSSST-K 1171

Query: 1925 QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQ-SSSYGPYGSGSGWSSSRGPYESG 1983
                G   SL    + S S  + SPS  R   GS + +S   P       S ++ P  SG
Sbjct: 1172 MKPQGKPSSL---MNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSG 1228

Query: 1984 SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHG 2043
            SG  S +    S SG  S  G   S S    T     S +  SSS    G+S   SSS  
Sbjct: 1229 SG-GSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSS--MSSSQN 1285

Query: 2044 QHGSGSSQSSGYGRQGSGSG--QSPGHGQRGSG-SRQSPSYGRHGSGSGRSS--SSGQHG 2098
            QHGS   +S    ++ S +       HG   SG   + P  G+ G  +  SS   S +H 
Sbjct: 1286 QHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHN 1345

Query: 2099 PGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSR 2158
               GE    G  E S    S  S  GS    S           ++S  +  GS+  +   
Sbjct: 1346 MSGGEFQ--GKREKSDKDKSKVSTSGSSVDSSK----------KTSESKNVGSTGVAKII 1393

Query: 2159 YGQHGSGS-----RQSSGHGRQGSGSGHSP---SRGRHGSG--SGHSSSHGQHGSGSGRS 2208
              +H  GS     + +     + SG G  P   S   +GS   SG +  H +      +S
Sbjct: 1394 ISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKS 1453

Query: 2209 SSRGPY----ESRSGHS 2221
             +  P     ES SG S
Sbjct: 1454 PAYTPQNLDSESESGSS 1470



 Score = 95.5 bits (236), Expect = 7e-19
 Identities = 160/651 (24%), Positives = 227/651 (34%), Gaps = 87/651 (13%)

Query: 962  SRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSG---- 1017
            S+SG         S SG +  +    S +  +LG    G  +G++      +  +     
Sbjct: 874  SQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSI 933

Query: 1018 -SGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 1076
             S    +  P       S S+GP  +    +  LG  +++     G G   S+       
Sbjct: 934  ISVAGKALAPADLMEHHSGSQGPLLT----TGDLGKEKTQKRVKEGNGTSNSTLSGPGLD 989

Query: 1077 GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 1136
             + G  S   S+ G+      +       G   S SS   R  +    + G    GS  R
Sbjct: 990  SKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSS-NRPFTPPTSTGGSKSPGSAGR 1048

Query: 1137 QSPSYGRHGSGSGRSSSSGQHGSGL-GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 1195
                 G       + +     G+ + G+ S    + SS   SSS S+  S   HSS    
Sbjct: 1049 SQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSK--SHHSHSSSSSS 1106

Query: 1196 HGSRSGQSSRGERHGSSSG--SSSHYGQHG-SGSRQSSGHGRQGSGSGHSPSRGRHGSGL 1252
              S SG+    +  GSSS   SSS Y   G SGS QS    + G   G SP   +HG   
Sbjct: 1107 SASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPIT-KHGLSS 1165

Query: 1253 GHSS------------------------SHGQHGSGSGR-SSSRGPYESRSGHSSVFGQH 1287
            G SS                        SH +   GS + +S   P       S      
Sbjct: 1166 GSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPI 1225

Query: 1288 ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSS 1347
             SGSG  S  S   S SG   S G   S S    T     S T  SSS+    SGSS SS
Sbjct: 1226 SSGSG-GSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFS--SSGSSMSS 1282

Query: 1348 GYGRHGAGSGQSPSRG------------RHG---SGSGHSSSY-GQHGSGSGWSS--SSG 1389
               +HG+  G+SPSR             +HG   SG G      GQ G  +  SS   S 
Sbjct: 1283 SQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSS 1342

Query: 1390 RHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGS 1449
            +H    G+    G  E S    S  +  GS    S           ++S  +  GS+  +
Sbjct: 1343 KHNMSGGEFQ--GKREKSDKDKSKVSTSGSSVDSSK----------KTSESKNVGSTGVA 1390

Query: 1450 SSSYGQHGSGS-----RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWS 1504
                 +H  GS     + +L      SG G  P  +  ++  GS   S  +P       S
Sbjct: 1391 KIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKN-YGSPLISGSTPKHERGSPS 1449

Query: 1505 SSRGP------YESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQH 1549
             S+ P       +S S   S +  +  ++  SS  G        +  H +H
Sbjct: 1450 HSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKH 1500



 Score = 95.1 bits (235), Expect = 9e-19
 Identities = 149/558 (26%), Positives = 197/558 (35%), Gaps = 103/558 (18%)

Query: 1823 GSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 1882
            GS S  SP+      G   +       S SG+        S SG +  F    S +  + 
Sbjct: 847  GSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTL 906

Query: 1883 GYTQHGSGSGHS-------------SSYEQHGSRSGQSSRGEQHGSSSG---SSSSYGQH 1926
            G    G  +G +             S     G     +   E H  S G   ++   G+ 
Sbjct: 907  GVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKE 966

Query: 1927 GSGSRQSLGHGQHGS---GSGQSPSPS-RGRHGSGSGQSSSYGPY-------GSGSGWSS 1975
             +  R   G+G   S   G G    P  R R  S  G+S    P        G     SS
Sbjct: 967  KTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSS 1026

Query: 1976 SRGPY----ESGSGHSSGLGHRESRS----------------------GQSSGYGQHGSS 2009
            S  P+     +G   S G   R                          G+ S + Q+ SS
Sbjct: 1027 SNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSS 1086

Query: 2010 ----SGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQ--SSGYGRQGS-GS 2062
                S  S +H  H S+S  S+S      +SG+  S    GS SS+  SS Y  QGS GS
Sbjct: 1087 GSVSSSGSKSHHSHSSSSSSSAS------TSGKMKSSKSEGSSSSKLSSSMYSSQGSSGS 1140

Query: 2063 GQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQ 2122
             QS    Q G     SP   +HG  SG  SSS +  P    SS      S    S S+S+
Sbjct: 1141 SQSKNSSQSGGKPGSSP-ITKHGLSSG--SSSTKMKPQGKPSSLMNPSLSKPNISPSHSR 1197

Query: 2123 HGSGSGHSSGYGQHGSRSGQSSRGERH-GSSSGSSSRYG-QHGSGSRQSSGHGRQGSGSG 2180
               GS   +   +    +  SS+ +    S SG S   G    SG + SSG G  GS S 
Sbjct: 1198 PPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQ 1257

Query: 2181 HSP---------SRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRS------------- 2218
             +P         S     SGS  SSS  QHGS  G+S SR    S +             
Sbjct: 1258 KTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTS 1317

Query: 2219 ---GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 2275
               G   + GQ     G S+  S H   S H  S G+     G+    D++ S    S S
Sbjct: 1318 GPGGEDPLDGQ----MGVSTNSSSHPMSSKHNMSGGEF---QGKREKSDKDKSKVSTSGS 1370

Query: 2276 HGQHGSGSSQSSSYGQQG 2293
                   +S+S + G  G
Sbjct: 1371 SVDSSKKTSESKNVGSTG 1388



 Score = 94.7 bits (234), Expect = 1e-18
 Identities = 174/711 (24%), Positives = 243/711 (34%), Gaps = 126/711 (17%)

Query: 1158 GSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSS 1217
            G+ L +SS  GH +S+   S  +  + + + ++         +G  S       S   ++
Sbjct: 804  GTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPS-------SDSPTN 856

Query: 1218 HYGQHGS-------GSRQSSGHGRQ----GSGSGHSPSRGRHGSGLGHSSSHGQHGSGSG 1266
            H+   G         S+  SG G +     S SG +       S   ++      G  +G
Sbjct: 857  HFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNG 916

Query: 1267 RSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQE 1326
             +  +G  ++ +   S+          +     H    G   + G  G    Q    +  
Sbjct: 917  ETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGN 976

Query: 1327 GSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGR---HGSGSGHSSSYGQHG--SG 1381
            G+S    S  G       +S      G    + P R +    G    HSSS       + 
Sbjct: 977  GTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTS 1036

Query: 1382 SGWSSSSGRHGSGS------------------------GQSSGFGHHESS-SWQSSGCTQ 1416
            +G S S G  G                           G+ S    + SS S  SSG   
Sbjct: 1037 TGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKS 1096

Query: 1417 HGSGSGHSSSYEQHGSRSGQSSRGERHGSSSG--SSSSYGQHGS-GSRQSLGHGQ----- 1468
            H S   HSSS     S SG+    +  GSSS   SSS Y   GS GS QS    Q     
Sbjct: 1097 HHS---HSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKP 1153

Query: 1469 -------HGSGSGQSP----------------------SPSRGRHGSGSGQ-SSSYSPYG 1498
                   HG  SG S                       SPS  R   GS + +S   P  
Sbjct: 1154 GSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVP 1213

Query: 1499 SGSGWSSSRGPYESGS--SHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 1556
                 S ++ P  SGS  SH SG     S SG  S  G   S S    T     S +  S
Sbjct: 1214 GTPPSSKAKSPISSGSGGSHMSG---TSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASS 1270

Query: 1557 SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSG--QSPGHGQRGSG-SRQSPSYGR 1613
            SS    G+S   SSS  QHGS   +S    ++ S +       HG   SG   + P  G+
Sbjct: 1271 SSFSSSGSS--MSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQ 1328

Query: 1614 HGSGSGRSS--SSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSG 1671
             G  +  SS   S +H    GE    G  E S    S  S  GS    S           
Sbjct: 1329 MGVSTNSSSHPMSSKHNMSGGEFQ--GKREKSDKDKSKVSTSGSSVDSSK---------- 1376

Query: 1672 QSSRGERHGSSSRSSSRYGQHGSGS-----RQSSGHGRQGSGSGQSP---SRGRHGSGLG 1723
            ++S  +  GS+  +     +H  GS     + +     + SG G  P   S   +GS L 
Sbjct: 1377 KTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPL- 1435

Query: 1724 HSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS 1774
             S S  +H  GS   S    Y  ++  S    + ESGS  +    Q+   S
Sbjct: 1436 ISGSTPKHERGSPSHSKSPAYTPQNLDS----ESESGSSIAEKSYQNSPSS 1482



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 146/561 (26%), Positives = 193/561 (34%), Gaps = 103/561 (18%)

Query: 2293 GSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 2352
            GS S  SP+      G   +       S SG+        S SG +  F    S +  + 
Sbjct: 847  GSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTL 906

Query: 2353 GYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 2412
            G    G  +G +     + + +   S     G +   +     H       L  G  G  
Sbjct: 907  GVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKE 966

Query: 2413 SGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2472
              Q     R + G+G+  S+   P         SR P   G         +++ +     
Sbjct: 967  KTQK----RVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADT----- 1017

Query: 2473 YGQHGSSSGHSSTHGQHG--STSGQSSSCGQHGASS------------------------ 2506
                G S  HSS++      +++G S S G  G S                         
Sbjct: 1018 ---EGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMV 1074

Query: 2507 GQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQ 2566
            G+ SSH Q+ S  S SS      SGS     H    S S          S SG+  SS  
Sbjct: 1075 GKPSSHSQYTSSGSVSS------SGSKSHHSHSSSSSSS---------ASTSGKMKSSKS 1119

Query: 2567 HGSGLGESSGFGHHESSSGQSSSYSQHGS-GSGHSSGYGQHGSRSGQSSRGERHGSSSGS 2625
             GS            SS   SS YS  GS GS  S    Q G + G SS   +HG SSGS
Sbjct: 1120 EGSS-----------SSKLSSSMYSSQGSSGSSQSKNSSQSGGKPG-SSPITKHGLSSGS 1167

Query: 2626 SSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSS-SRGPY 2684
            SS   +     + SS      S    SPS  R   G    +S  +   G+  SS ++ P 
Sbjct: 1168 SST--KMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPI 1225

Query: 2685 ESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS 2744
             S  G     G H SG+          S SG   S G   S S    T     S T  SS
Sbjct: 1226 SSGSG-----GSHMSGTS---------SSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSS 1271

Query: 2745 SYGHRGSGSSQSSGYGRHGAGSGQS---------------LSHGRHGSG-SGQSSSYGQH 2788
            S+    SGSS SS   +HG+  G+S               L HG   SG  G+    GQ 
Sbjct: 1272 SFS--SSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQM 1329

Query: 2789 GSGSGQSSG--YSQHGSGSGQ 2807
            G  +  SS    S+H    G+
Sbjct: 1330 GVSTNSSSHPMSSKHNMSGGE 1350



 Score = 79.7 bits (195), Expect = 4e-14
 Identities = 116/428 (27%), Positives = 155/428 (36%), Gaps = 57/428 (13%)

Query: 166  SGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGS 225
            S  H+S+S  SSS    +     S   G   S    S    Q  SGS QS ++   G   
Sbjct: 1094 SKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKP 1153

Query: 226  GQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ 285
            G              SS  ++HG  SG SS   +   +   SS      S    S S+ +
Sbjct: 1154 G--------------SSPITKHGLSSGSSS--TKMKPQGKPSSLMNPSLSKPNISPSHSR 1197

Query: 286  HGSGSRQSLGHGRQGSG---SRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGS 342
               GS +     +   G   S ++ S +  GSG  H S     G+ SS           S
Sbjct: 1198 PPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMS-----GTSSSSGMKSSSGLGSS 1252

Query: 343  GQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQ 402
            G  S      S S  +S  S   SGS  SSSQ QHGS+ G++ S  +  S          
Sbjct: 1253 GSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSL--------- 1303

Query: 403  HESASRHSSGRGQHSSG-SGQSPGHGQRG--SGSGQSPSSGQHGTGFGR---------SS 450
              +A       G  +SG  G+ P  GQ G  + S   P S +H    G            
Sbjct: 1304 --TAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKD 1361

Query: 451  SSGPYVSGSGYSSGFGHHESSSEHSSG-----YTQHGSGSGHSSGHGQHGSRSGQSSRGE 505
             S    SGS   S     ES +  S+G      ++H  GS           + G+SS GE
Sbjct: 1362 KSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTL-QKPGESS-GE 1419

Query: 506  RQGSSAGSSSSYGQH-GSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYG 564
                   SS +YG    SGS     H R      +SP+ +    +S S   SS     Y 
Sbjct: 1420 GLRPQMASSKNYGSPLISGSTPK--HERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQ 1477

Query: 565  SGRSSSRG 572
            +  SS  G
Sbjct: 1478 NSPSSDDG 1485



 Score = 62.4 bits (150), Expect = 6e-09
 Identities = 113/518 (21%), Positives = 177/518 (34%), Gaps = 52/518 (10%)

Query: 2332 GSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSS 2391
            G+    SS  GH +S+ + S  +  + + + ++   +     +G  S       S   ++
Sbjct: 804  GTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPS-------SDSPTN 856

Query: 2392 SYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYE 2451
             +   G      L + Q  SG G+          S SG +  +  + S +  +       
Sbjct: 857  HFFHDGVDFNPDLLNSQSQSGFGEEYFDE----SSQSGDNDDFKGFASQALNTLGVPMLG 912

Query: 2452 SGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSS 2511
              +G +   G+ ++ +   S     G +   +     H  + G   + G  G    Q   
Sbjct: 913  GDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRV 972

Query: 2512 HGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGL 2571
               +G+ +S  SG G       +S      G  S+  P   +     G+S S        
Sbjct: 973  KEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGK-SKDKPPKRKKADTEGKSPSHSSSNRPF 1031

Query: 2572 GESSGFGHHESSSGQSSSYSQHGSGSGH-----------SSGYGQHGSRSGQSSRGERHG 2620
               +  G  +S      S +  G  +             +   G+  S S  +S G    
Sbjct: 1032 TPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSV-- 1089

Query: 2621 SSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSS 2680
            SSSGS SH+    S S  +S  G+  S    S S G   S L  S    Q  SGS +S +
Sbjct: 1090 SSSGSKSHHSHSSSSSSSASTSGKMKS----SKSEGSSSSKLSSSMYSSQGSSGSSQSKN 1145

Query: 2681 RGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST 2740
                               G   SS  ++HG  SG   S  +       SS  +   S  
Sbjct: 1146 --------------SSQSGGKPGSSPITKHGLSSGS--SSTKMKPQGKPSSLMNPSLSKP 1189

Query: 2741 GQSSSYGHRGSGSSQSSGYGRHGAGSG-QSLSHGRHGSGSGQSSSYGQHGSGSGQSSGY- 2798
              S S+     GS + +   +   G+   S +     SGSG     G H SG+  SSG  
Sbjct: 1190 NISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSG-----GSHMSGTSSSSGMK 1244

Query: 2799 SQHGSGSGQDGYSYCKGGSNHDGGSSGSYFLSFPSSTS 2836
            S  G GS           SN    SS S+  S  S +S
Sbjct: 1245 SSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSS 1282


>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
          Length = 416

 Score =  103 bits (258), Expect = 2e-21
 Identities = 108/372 (29%), Positives = 147/372 (39%), Gaps = 40/372 (10%)

Query: 897  GSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSS 956
            GSG       G   +G+    + G HG G   S G G   + G+ +G    G+     S 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG--KAIGKEAG----GAAGSKVSE 69

Query: 957  YEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGS 1016
                G+R    +   Q     G++ + G     +  +LG+  H  G     +    RHG+
Sbjct: 70   ALGQGTREAVGTGVRQV-PGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHGA 125

Query: 1017 GSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 1076
             + + S  G       W +S G    GS    GLG      GQ  G   +    G    H
Sbjct: 126  DAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------GQGQG---NPGGLGTPWVH 174

Query: 1077 GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 1136
            G  G+++G S      GA  GQ  + G    G++      + G GS ++    +   G  
Sbjct: 175  GYPGNSAG-SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE---GCT 230

Query: 1137 QSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQH 1196
              P     GSG G S+S G  GS  G S    + ++++G SS  S  GS SG SSG G  
Sbjct: 231  NPPP---SGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG-GSS 286

Query: 1197 GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSG-HGRQGSGSGHSP---SRGRHGSGL 1252
            G  SG S      G S G S      GS +  SSG HG  G G+GH P     G    G 
Sbjct: 287  GGSSGNS------GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGS 340

Query: 1253 GHSSSHGQHGSG 1264
            G S   G  G G
Sbjct: 341  GESGIQGFRGQG 352



 Score =  103 bits (257), Expect = 2e-21
 Identities = 106/379 (27%), Positives = 143/379 (37%), Gaps = 53/379 (13%)

Query: 1836 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 1895
            GSG       G+  +G+    + G HG G   S G G       ++ G    G+     S
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68

Query: 1896 SYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1955
                 G+R    + G +     G++ + G     +  +LG+  H  G     +    RHG
Sbjct: 69   EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124

Query: 1956 SGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST 2015
            + + + S  G  G    W +S G    GS    GLG            GQ   + G   T
Sbjct: 125  ADAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------------GQGQGNPGGLGT 170

Query: 2016 HGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2075
               HG     + S G +     Q +  GQ G+G   + G   QG+ +   PG+G   + +
Sbjct: 171  PWVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASN 224

Query: 2076 RQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2135
            +         SGSG  SS+   G G           S SG S S S   + +G SSG   
Sbjct: 225  QNEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSS 273

Query: 2136 HGSRSGQSSRGERHGSSSGSSSRYGQHGSGS-------RQSSGHGRQGSGSGHSP---SR 2185
             GS SG SS G   GSS  S    G  GS S         S  HG  G G+GH P     
Sbjct: 274  SGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP 333

Query: 2186 GRHGSGSGHSSSHGQHGSG 2204
            G    GSG S   G  G G
Sbjct: 334  GNEARGSGESGIQGFRGQG 352



 Score =  103 bits (256), Expect = 3e-21
 Identities = 109/373 (29%), Positives = 148/373 (39%), Gaps = 41/373 (10%)

Query: 1366 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSS 1425
            GSG       G+  +G+    + G HG G   S G G       ++ G    G+     S
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68

Query: 1426 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1485
                 G+R    + G R     G++ + G     +  +LG+  H  G     +    RHG
Sbjct: 69   EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124

Query: 1486 SGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSST 1545
            + + + S     G    W +S G    GS    GLG      GQ  G   +    G    
Sbjct: 125  ADAVRGSWQGVPGHNGAWETSGGHGIFGSQ--GGLG------GQGQG---NPGGLGTPWV 173

Query: 1546 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 1605
            HG  G+++G S      GA  GQ  + G    G++      + G GS ++    +   G 
Sbjct: 174  HGYPGNSAG-SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE---GC 229

Query: 1606 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 1665
               P     GSG G S+S G  GS  G S    + ++++G SS  S  GS SG SSG G 
Sbjct: 230  TNPPP---SGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG-GS 285

Query: 1666 HGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSG-HGRQGSGSGQSP---SRGRHGSG 1721
             G  SG S  G R  S S SS      GS +  SSG HG  G G+G  P     G    G
Sbjct: 286  SGGSSGNSG-GSRGDSGSESS-----WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARG 339

Query: 1722 LGHSSSHGQHGSG 1734
             G S   G  G G
Sbjct: 340  SGESGIQGFRGQG 352



 Score =  100 bits (248), Expect = 3e-20
 Identities = 114/408 (27%), Positives = 161/408 (39%), Gaps = 52/408 (12%)

Query: 1706 GSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 1765
            GSG       G   +G     + G HG G   S   G            G+   G+  S 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66

Query: 1766 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 1825
                 G G+      G        ++  D  G+  G+++    H  G++     G+Q   
Sbjct: 67   VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAA----HALGNT-GHEIGRQAED 119

Query: 1826 ---SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 1882
                G    RG      GH+ ++   G    + S  G  G G G   G G    + W   
Sbjct: 120  VIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVH- 174

Query: 1883 GYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 1942
            GY  + +GS         G+  GQ   G      + +  +  Q G GS ++    +  + 
Sbjct: 175  GYPGNSAGS---FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT- 230

Query: 1943 SGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2002
               +P PS    GSG G S+S G  GS SG S S    ++ +G SSG     S SG SSG
Sbjct: 231  ---NPPPS----GSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG----GSSSGSSSG 279

Query: 2003 YGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSS-SHGQHGSGSSQSSGY---GRQ 2058
             G  G SSG SS  G  G + G S S    G+S+G SS +HG  G G+    G    G +
Sbjct: 280  -GSSGGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNE 336

Query: 2059 GSGSGQSPGHGQRGSG-SRQSPSYGRHGS----GSGRSSSSGQHGPGL 2101
              GSG+S   G RG G S       + G+    GSG +  + +  PG+
Sbjct: 337  ARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPGM 384



 Score = 99.4 bits (246), Expect = 5e-20
 Identities = 105/379 (27%), Positives = 141/379 (37%), Gaps = 53/379 (13%)

Query: 2306 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 2365
            GSG       G+  +G+    + G HG G   S G G       ++ G    G+     S
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68

Query: 2366 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 2425
                 G+R    + G R     G++ + G     +  +LG+  H  G     +    RHG
Sbjct: 69   EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124

Query: 2426 SGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST 2485
            + + + S     G    W +S G    GS    GLG            GQ   + G   T
Sbjct: 125  ADAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------------GQGQGNPGGLGT 170

Query: 2486 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2545
               HG     + S G +     Q +  GQ G+G   + G   QG+ +   PG+G   + +
Sbjct: 171  PWVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASN 224

Query: 2546 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2605
            +         SGSG  SS+   GSG           S SG S S S   + +G SSG   
Sbjct: 225  QNEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSS 273

Query: 2606 HGSRSGQSSRGERHGSSSGSSSHYGQHGSGS-------RQSSGHGRQGSGSGQSP---SR 2655
             GS SG SS G   GSS  S    G  GS S         S  HG  G G+G  P     
Sbjct: 274  SGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP 333

Query: 2656 GRHGSGLGHSSSHGQHGSG 2674
            G    G G S   G  G G
Sbjct: 334  GNEARGSGESGIQGFRGQG 352



 Score = 98.6 bits (244), Expect = 8e-20
 Identities = 111/399 (27%), Positives = 158/399 (39%), Gaps = 74/399 (18%)

Query: 365 GSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSP 424
           GSG       G+  + +    + G HG     S   G+           G+ + G+  S 
Sbjct: 17  GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGK---------AIGKEAGGAAGSK 66

Query: 425 GHGQRGSGSGQSPSSG-QHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGS 483
                G G+ ++  +G +   GFG + + G  V  + ++ G   HE   + +    +HG+
Sbjct: 67  VSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQ-AEDVIRHGA 125

Query: 484 GS---------GH------SSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSL 528
            +         GH      S GHG  GS+ G   +G+      G+   +G  G+ S  S 
Sbjct: 126 DAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-SAGSF 184

Query: 529 GHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRG-----PYESGSGHSSG 583
           G +  G+  GQ  +   G    G+    +    GYGS R+S++      P  SGSG  S 
Sbjct: 185 GMNPQGAPWGQGGNG--GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS- 241

Query: 584 LGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGS 643
                S SG  SG  Q GSS   S+    +GS+SG SSS    G++SG SS         
Sbjct: 242 -----SNSGGGSG-SQSGSSGSGSNGDNNNGSSSGGSSS----GSSSGGSSG-------- 283

Query: 644 SQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNG-PHGSVSGQSSGFG 702
                 G  G  SG S              S G  GS S W SS G   G+  G   G G
Sbjct: 284 ------GSSGGSSGNS------------GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNG 325

Query: 703 HKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQ 741
           HK G  +  G    GSG S   G+R  G  S     S++
Sbjct: 326 HKPGC-EKPGNEARGSGESGIQGFRGQGVSSNMREISKE 363



 Score = 97.8 bits (242), Expect = 1e-19
 Identities = 113/411 (27%), Positives = 156/411 (37%), Gaps = 61/411 (14%)

Query: 782  GSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQ 841
            GS        G+  +GT+   + GH   G G A   G    G   G  + G A+G   S+
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALGH---GLGDALSEGV---GKAIG-KEAGGAAGSKVSE 69

Query: 842  GRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSG 901
                 T     +  +     G + + G     + HA G   H  G               
Sbjct: 70   ALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-------------- 115

Query: 902  QSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHG 961
            Q+    RHG+ + R S  G  G      +  GH    G   G    G G+          
Sbjct: 116  QAEDVIRHGADAVRGSWQGVPGHNGAWETSGGH-GIFGSQGGLGGQGQGN---------- 164

Query: 962  SRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQS 1021
               G       HG    S+ S+G +  G+      GQ G+G      P+ G +  G+   
Sbjct: 165  --PGGLGTPWVHGYPGNSAGSFGMNPQGAPW----GQGGNGG----PPNFGTNTQGAVAQ 214

Query: 1022 SSYGPYRSGSGWSSSRGPYESGSGHSS-----GLGHRESRSGQ-SSGYGQHGSSSGHSST 1075
              YG  R+ +       P  SGSG  S     G G +   SG  S+G   +GSSSG SS+
Sbjct: 215  PGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSS 274

Query: 1076 HGQHGSTSGQSS--SCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSGSG-----QSPG 1127
                G +SG SS  S G  G S G S S    GS +  SSG +G  G G+G     + PG
Sbjct: 275  GSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG 334

Query: 1128 HGQRGSGSRQSPSYGRHGSG-SGRSSSSGQHGSGL--GESSGFGHHESSSG 1175
            +  RGSG  +S   G  G G S       + G+ L  G    + + E+S G
Sbjct: 335  NEARGSG--ESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPG 383



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 109/370 (29%), Positives = 154/370 (41%), Gaps = 38/370 (10%)

Query: 2493 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG--YGRQGSGSGQSPGHGQRGSGSRQSPS 2550
            SG+ S+    G + G++  HG  G   S+  G   G++  G+  S      G G+R++  
Sbjct: 26   SGEEST----GTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVG 80

Query: 2551 YG-RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS---------GH- 2599
             G R   G G + + G        + G   HE    Q+    +HG+ +         GH 
Sbjct: 81   TGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIRHGADAVRGSWQGVPGHN 139

Query: 2600 -----SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPS 2654
                 S G+G  GS+ G   +G+ +    G+   +G  G+ S  S G   QG+  GQ  +
Sbjct: 140  GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-SAGSFGMNPQGAPWGQGGN 198

Query: 2655 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHS-SVFGQHESGSGHSSAYSQHGSG 2713
             G    G     +  Q G GS R+S++    +    S S  G   SG G  S     GSG
Sbjct: 199  GGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSG 258

Query: 2714 SGHFCSQGQH--GSTSGQSSTFDQEGSSTGQS-SSYGHRGSGSSQSSGYGRHGAGSGQSL 2770
            S    + G    GS+SG SS     GSS G S +S G RG   S+SS     G+ SG   
Sbjct: 259  SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSG--- 315

Query: 2771 SHGRHGSGSGQS---SSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGSY 2827
            +HG  G G+G        G    GSG+S      G G   +     K G+   GGS  +Y
Sbjct: 316  NHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNY 375

Query: 2828 FLSFPSSTSP 2837
                 S TSP
Sbjct: 376  ---RNSETSP 382



 Score = 95.9 bits (237), Expect = 5e-19
 Identities = 117/419 (27%), Positives = 165/419 (39%), Gaps = 61/419 (14%)

Query: 1236 GSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 1295
            GSG       G   +G     + G HG G   S   G            G+   G+  S 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66

Query: 1296 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS-SYGHRGSG-SSQSSGYGRHG 1353
                 G G+      G        ++  D  G+  G+++ + G+ G     Q+    RHG
Sbjct: 67   VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAAHALGNTGHEIGRQAEDVIRHG 124

Query: 1354 AGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 1413
            A +     RG      GH+ ++   G    + S  G  G G G   G G    + W    
Sbjct: 125  ADA----VRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVHG- 175

Query: 1414 CTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1473
               +   S  S      G+  GQ   G      + +  +  Q G GS ++    +  +  
Sbjct: 176  ---YPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT-- 230

Query: 1474 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGY 1533
              +P PS    GSG G S+S    G GSG        +SGSS S   G  ++ +G SSG 
Sbjct: 231  --NPPPS----GSGGGSSNS----GGGSG-------SQSGSSGSGSNG--DNNNGSSSGG 271

Query: 1534 GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSGS 1592
               GSSSG SS     G +SG SS  G  G S G S S    GS +  SSG +G  G G+
Sbjct: 272  SSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGN 324

Query: 1593 GQSPGHGQRGSGSRQSPSYGRHG-SGSGRSSSS---GQHGSGL--GESSGFGHHESSSG 1645
            G  PG  + G+ +R S   G  G  G G SS+     + G+ L  G    + + E+S G
Sbjct: 325  GHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPG 383



 Score = 95.5 bits (236), Expect = 7e-19
 Identities = 119/395 (30%), Positives = 156/395 (39%), Gaps = 38/395 (9%)

Query: 484 GSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSP 543
           GSG + G  Q G  S  ++ GE  G   G + S G   +  +++ G     +GS  S + 
Sbjct: 17  GSGEA-GPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGG----AAGSKVSEAL 71

Query: 544 SRGRHES---GSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQES-RSGQSSGYGQ 599
            +G  E+   G RQ   +G       R          +GH  G   ++  R G  +  G 
Sbjct: 72  GQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131

Query: 600 HGSSSGHSS---THGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQ--QGS 654
                GH+    T G HG    Q    GQ     G   +   HG   + +  +G   QG+
Sbjct: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGA 191

Query: 655 GSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYS 714
             GQ  + G          +  Q G GS  +S+     +    S   G  S SG  SG S
Sbjct: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG-S 250

Query: 715 QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGH 774
           Q GS  S S+G   +GS SG        GSSSG SSS G  G  S  SSG+   G   G 
Sbjct: 251 QSGSSGSGSNGDNNNGSSSG--------GSSSG-SSSGGSSGGSSGGSSGN--SGGSRGD 299

Query: 775 SPSRVRHGSSSGHSS-SHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGS 833
           S S    GSS+G SS +HG  G G      C   E    +A G G  ESG  QG+   G 
Sbjct: 300 SGSESSWGSSTGSSSGNHGGSGGGNGHKPGC---EKPGNEARGSG--ESGI-QGFRGQG- 352

Query: 834 ASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYG 868
                SS  R  S  G     G  D+     +S G
Sbjct: 353 ----VSSNMREISKEGNRLLGGSGDNYRNSETSPG 383



 Score = 95.5 bits (236), Expect = 7e-19
 Identities = 105/371 (28%), Positives = 152/371 (40%), Gaps = 55/371 (14%)

Query: 1787 SGQSSTFDQEGSSTGQSSSHGQHGSGSSQS--SSYGQQGSGSGQSPSRGRHGSGSGHSSS 1844
            SG+ ST    G++ G++  HG  G   S+    + G++  G+  S      G G+  +  
Sbjct: 26   SGEEST----GTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVG 80

Query: 1845 YG-QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGS---------GHS 1894
             G +   G G + + G     +  + G   HE    Q+    +HG+ +         GH+
Sbjct: 81   TGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIRHGADAVRGSWQGVPGHN 139

Query: 1895 SSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQ---HG--SGSRQSLGHGQHGSGSGQSPS- 1948
             ++E  G      S+G   G   G+    G    HG    S  S G    G+  GQ  + 
Sbjct: 140  GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNG 199

Query: 1949 --PSRGRHGSGSGQSSSYG---------------PYGSGSGWSSSRGPYESGSGHSSGLG 1991
              P+ G +  G+     YG               P GSG G S+S G   S SG S    
Sbjct: 200  GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGS 259

Query: 1992 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQ 2051
            + ++ +G SSG    GSSSG SS     G +SG SS  G  G S G S S    GS +  
Sbjct: 260  NGDNNNGSSSGGSSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGS 312

Query: 2052 SSG-YGRQGSGSG-----QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGES- 2104
            SSG +G  G G+G     + PG+  RGSG      +   G  S     S +    LG S 
Sbjct: 313  SSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSG 372

Query: 2105 SGFGHHESSSG 2115
              + + E+S G
Sbjct: 373  DNYRNSETSPG 383



 Score = 95.1 bits (235), Expect = 9e-19
 Identities = 112/408 (27%), Positives = 160/408 (39%), Gaps = 52/408 (12%)

Query: 2176 GSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 2235
            GSG       G   +G+    + G HG G   S   G            G+   G+  S 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66

Query: 2236 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 2295
                 G G+      G        ++  D  G+  G+++    H  G++     G+Q   
Sbjct: 67   VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAA----HALGNT-GHEIGRQAED 119

Query: 2296 ---SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 2352
                G    RG      GH+ ++   G    + S  G  G G G   G G    + W   
Sbjct: 120  VIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVH- 174

Query: 2353 GYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 2412
            GY  + +GS         G+  GQ   G      + +  +  Q G GS ++    +  + 
Sbjct: 175  GYPGNSAGS---FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT- 230

Query: 2413 SGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2472
               +P PS    GSG G S+S    GS SG S S    ++ +G SSG     S SG SSG
Sbjct: 231  ---NPPPS----GSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG----GSSSGSSSG 279

Query: 2473 YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSS-SHGQHGSGSSQSSGY---GRQ 2528
             G  G SSG SS  G  G + G S S    G+S+G SS +HG  G G+    G    G +
Sbjct: 280  -GSSGGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNE 336

Query: 2529 GSGSGQSPGHGQRGSG-SRQSPSYGRHGS----GSGRSSSSGQHGSGL 2571
              GSG+S   G RG G S       + G+    GSG +  + +   G+
Sbjct: 337  ARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPGM 384



 Score = 94.7 bits (234), Expect = 1e-18
 Identities = 105/376 (27%), Positives = 151/376 (40%), Gaps = 45/376 (11%)

Query: 1553 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG--YGRQGSGSGQSPGHGQRGSGSRQSPS 1610
            SG+ S+    G + G++  HG  G   S+  G   G++  G+  S      G G+R++  
Sbjct: 26   SGEEST----GTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVG 80

Query: 1611 YG-RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS---------GH- 1659
             G R   G G + + G        + G   HE    Q+    +HG+ +         GH 
Sbjct: 81   TGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIRHGADAVRGSWQGVPGHN 139

Query: 1660 -----SSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPS 1714
                 S G+G  GS+ G   +G+ +     +   +G  G+ S  S G   QG+  GQ  +
Sbjct: 140  GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-SAGSFGMNPQGAPWGQGGN 198

Query: 1715 RGRHGSGLGHSSSHGQHGSGSGRSSSR-----GPYESRSGHSSVFGQHESGSGHSSAYSQ 1769
             G    G     +  Q G GS R+S++      P  S SG     G   SG G  S    
Sbjct: 199  GGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGG----GSSNSGGGSGSQSGS 254

Query: 1770 HGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQS 1829
             GSGS        +GS+SG SS+    G S+G SS      SG S+  S  +   GS   
Sbjct: 255  SGSGSN---GDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311

Query: 1830 PSRGRH---GSGSGHSSSYGQHGSGSGWSSSSGRHG-SGSGQSSGFGHHESSSWQSSGYT 1885
             S G H   G G+GH     + G+ +  S  SG  G  G G SS          +  G  
Sbjct: 312  SSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLG-- 369

Query: 1886 QHGSGSGHSSSYEQHG 1901
              GSG  + +S    G
Sbjct: 370  --GSGDNYRNSETSPG 383



 Score = 94.7 bits (234), Expect = 1e-18
 Identities = 104/373 (27%), Positives = 159/373 (42%), Gaps = 59/373 (15%)

Query: 2257 SGQSSTFDQEGSSTGQSSSHGQHGSGSSQS--SSYGQQGSGSGQSPSRGRHGSGSGHSSS 2314
            SG+ ST    G++ G++  HG  G   S+    + G++  G+  S      G G+  +  
Sbjct: 26   SGEEST----GTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVG 80

Query: 2315 YG-QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGS---------GHS 2364
             G +   G G + + G     +  + G   HE    Q+    +HG+ +         GH+
Sbjct: 81   TGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIRHGADAVRGSWQGVPGHN 139

Query: 2365 SSYEQHG------SRSGQSSRGER----------HGSSSGSSSSYGQHGSGSRQSLGHGQ 2408
             ++E  G      S+ G   +G+           HG    S+ S+G +  G+    G   
Sbjct: 140  GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNG 199

Query: 2409 HGSGSGQSPSPSRGRHGSGSGQSSSYS-------PYGSGSGWSSSRGPYESGSGHSSGLG 2461
                 G +   +  + G GS ++S+ +       P GSG G S+S G   S SG S    
Sbjct: 200  GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGS 259

Query: 2462 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQ 2521
            + ++ +G SSG    GSSSG SS     G +SG SS  G  G S G S S    GS +  
Sbjct: 260  NGDNNNGSSSGGSSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGS 312

Query: 2522 SSG-YGRQGSGSG-----QSPGHGQRGSGSRQSPSYGRHGSG-SGRSSSSGQHGSGL--G 2572
            SSG +G  G G+G     + PG+  RGSG  +S   G  G G S       + G+ L  G
Sbjct: 313  SSGNHGGSGGGNGHKPGCEKPGNEARGSG--ESGIQGFRGQGVSSNMREISKEGNRLLGG 370

Query: 2573 ESSGFGHHESSSG 2585
                + + E+S G
Sbjct: 371  SGDNYRNSETSPG 383



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 120/419 (28%), Positives = 165/419 (39%), Gaps = 70/419 (16%)

Query: 196 GSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSS 255
           GSG       G+  +G+    +   HG G   S G  +   + G+ +G +   +GS  S 
Sbjct: 17  GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGK---AIGKEAGGA---AGSKVSE 69

Query: 256 GYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSG 315
             GQ G+R    + G R     G++ + G     +  +LG+     G RQ+   +RHG+ 
Sbjct: 70  ALGQ-GTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIG-RQAEDVIRHGAD 126

Query: 316 SGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQG 375
           +   S  G  G   ++  S GH   GS         + G G        G G G+    G
Sbjct: 127 AVRGSWQGVPGHNGAWETSGGHGIFGS---------QGGLG--------GQGQGNPGGLG 169

Query: 376 Q---HGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQ---- 428
               HG     A S G +     Q + +GQ  +    + G   ++ G+   PG+G     
Sbjct: 170 TPWVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGT--NTQGAVAQPGYGSVRAS 223

Query: 429 -RGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGH 487
            +  G    P SG  G   G S+S G    GSG  SG     SS   S+G   +GS SG 
Sbjct: 224 NQNEGCTNPPPSGSGG---GSSNSGG----GSGSQSG-----SSGSGSNGDNNNGSSSGG 271

Query: 488 SSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLG---------HSRHGSGSG 538
           SS     GS SG SS G   GSS  S  S G   SGS  S G         H   G G+G
Sbjct: 272 SSS----GSSSGGSSGGSSGGSSGNSGGSRGD--SGSESSWGSSTGSSSGNHGGSGGGNG 325

Query: 539 QSPSPSR-GRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSG 596
             P   + G    GS +S   G  G G   S+ R   + G+    G G     S  S G
Sbjct: 326 HKPGCEKPGNEARGSGESGIQGFRGQGVS-SNMREISKEGNRLLGGSGDNYRNSETSPG 383



 Score = 88.6 bits (218), Expect = 8e-17
 Identities = 93/314 (29%), Positives = 123/314 (39%), Gaps = 14/314 (4%)

Query: 2516 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ-SPSYGRHGSGSGRSSSSGQHGSGLGES 2574
            G      SG    G+  G++ GHG   + S     + G+   G+  S  S   G G  E+
Sbjct: 19   GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78

Query: 2575 SGFGHHESSS-GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQ-- 2631
             G G  +    G + +       + H+ G   H     Q+    RHG+ +   S  G   
Sbjct: 79   VGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGVPG 137

Query: 2632 HGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHS 2691
            H      S GHG  GS  G       +  GLG    HG  G+ +G S    P  +  G  
Sbjct: 138  HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG-SFGMNPQGAPWGQG 196

Query: 2692 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGS 2751
               G    G+    A +Q G GS    +Q + G T+   S     GS  G S+S G  GS
Sbjct: 197  GNGGPPNFGTNTQGAVAQPGYGSVRASNQNE-GCTNPPPS-----GSGGGSSNSGGGSGS 250

Query: 2752 GSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYS 2811
             S  SSG G +G  +  S S G     S   SS G  G  SG S G S+  SGS     S
Sbjct: 251  QSG-SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG-SRGDSGSESSWGS 308

Query: 2812 YCKGGSNHDGGSSG 2825
                 S + GGS G
Sbjct: 309  STGSSSGNHGGSGG 322



 Score = 88.2 bits (217), Expect = 1e-16
 Identities = 96/349 (27%), Positives = 140/349 (40%), Gaps = 32/349 (9%)

Query: 974  GSSSGSSSSYGQHGSGSR--QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGS 1031
            GS        G+  +G+   ++LGHG  G    +    + G+   G+  S        G+
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75

Query: 1032 GWSSSRGPYE-SGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG 1090
              +   G  +  G G +  LG+R   +  + G   H      +    +HG+ + + S  G
Sbjct: 76   REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQG 134

Query: 1091 QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG----HGQRGSGSR------QSPS 1140
              G +    +S G HG   SQ  G G QG G+    G    HG  G+ +       Q   
Sbjct: 135  VPGHNGAWETSGG-HGIFGSQG-GLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAP 192

Query: 1141 YGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ--HGSGSGHSSGYGQHGS 1198
            +G+ G+G     + G +  G     G+G   +S+      +    GSG G S+  G  GS
Sbjct: 193  WGQGGNGG--PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGS 250

Query: 1199 RSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGS----GLGH 1254
            +SG S  G    +++GSSS     GS S  SSG    GS      SRG  GS    G   
Sbjct: 251  QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSST 310

Query: 1255 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSG 1303
             SS G HG GSG  +   P   + G+ +       GSG S      G G
Sbjct: 311  GSSSGNHG-GSGGGNGHKPGCEKPGNEA------RGSGESGIQGFRGQG 352



 Score = 88.2 bits (217), Expect = 1e-16
 Identities = 108/377 (28%), Positives = 147/377 (38%), Gaps = 43/377 (11%)

Query: 2001 SGYGQHGSSSGHSSTHGQHGSAS-GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG-RQ 2058
            SG    G++ G +  HG   + S G   + G+    +  S      G G+ ++ G G RQ
Sbjct: 26   SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85

Query: 2059 GSGSGQSPGHGQRGSGS------------RQSPSYGRHGSGSGRSSSSGQHGPGLGESSG 2106
              G G +   G R   +            RQ+    RHG+ + R S  G  G        
Sbjct: 86   VPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHN------ 139

Query: 2107 FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGS--SSGSSSRYGQHGS 2164
             G  E+S G     SQ G G       G  G+       G   GS   +   + +GQ G+
Sbjct: 140  -GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGN 198

Query: 2165 GSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSR--GPYESRSGHSS 2222
            G   + G   QG+ +   P  G   + + +        SGSG  SS   G   S+SG S 
Sbjct: 199  GGPPNFGTNTQGAVA--QPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG 256

Query: 2223 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSG 2282
                 ++ +G SS  S  GS SG     G  G +SG SS     G S G S S    GS 
Sbjct: 257  SGSNGDNNNGSSSGGSSSGSSSG-----GSSGGSSGGSS--GNSGGSRGDSGSESSWGSS 309

Query: 2283 S-SQSSSYGQQGSGSGQSP---SRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQS 2338
            + S S ++G  G G+G  P     G    GSG S   G  G G    SS+ R  S  G  
Sbjct: 310  TGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG---VSSNMREISKEGNR 366

Query: 2339 --SGFGHHESSSWQSSG 2353
               G G +  +S  S G
Sbjct: 367  LLGGSGDNYRNSETSPG 383



 Score = 87.8 bits (216), Expect = 1e-16
 Identities = 89/328 (27%), Positives = 132/328 (40%), Gaps = 38/328 (11%)

Query: 180 GEQNSDSHQSSGRGQCGSGSGQSPNYGQH---GSGSGQSS---SNDTHGSGSGQSSGFSQ 233
           G + S++     R   G+G  Q P +G     G+  G+++    N  H  G  Q+    +
Sbjct: 64  GSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIR 122

Query: 234 HKSSS--GQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGS------------ 279
           H + +  G   G   H      S G+G  GS+ G   +G+ +    G+            
Sbjct: 123 HGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG 182

Query: 280 -------SSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYS 332
                   + +GQ G+G   + G   QG+ ++     VR  + +   ++    GSG   S
Sbjct: 183 SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242

Query: 333 YSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGS 392
            S G   S SG +      ++ +G SSG S  GS SG SS     GS+     S G  GS
Sbjct: 243 NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGS 302

Query: 393 SSRQSSSYGQHESASRHSSGRGQHSSGSGQSPG---HGQRGSGSGQSPSSGQHGTGFGRS 449
            S   SS G   S+S +  G G    G+G  PG    G    GSG+S   G  G G   S
Sbjct: 303 ESSWGSSTG---SSSGNHGGSG---GGNGHKPGCEKPGNEARGSGESGIQGFRGQGVS-S 355

Query: 450 SSSGPYVSGSGYSSGFGHHESSSEHSSG 477
           +       G+    G G +  +SE S G
Sbjct: 356 NMREISKEGNRLLGGSGDNYRNSETSPG 383



 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 102/376 (27%), Positives = 141/376 (37%), Gaps = 29/376 (7%)

Query: 987  GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS-GQSSSYGPYRSGSGWSSSRGPYESGSG 1045
            GSG    L  G+  +G+    +   G   + S G   + G    G+  S        G+ 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76

Query: 1046 HSSGLGHRESRS-GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQ 1104
             + G G R+    G +   G     + H+  +  H     Q+    +HGA + + S  G 
Sbjct: 77   EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGV 135

Query: 1105 --HGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLG 1162
              H      S G+G  GS  G   G GQ   G   +P    +   S  S      G+  G
Sbjct: 136  PGHNGAWETSGGHGIFGSQGGLG-GQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWG 194

Query: 1163 ESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ-------HGSRSGQSSRGERHGSSSGS 1215
            +    G     +    + +Q G GS  +S   +        GS  G S+ G   GS SGS
Sbjct: 195  QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGS 254

Query: 1216 SSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSS--SHGQHGSGSGRSSSRGP 1273
            S      GSG   S+G    GS SG S S    G   G SS  S G  G   G S S   
Sbjct: 255  S------GSG---SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305

Query: 1274 YESRSGHSS-VFGQHESGSGHSSAYSQHGS---GSGHFCSQGQHG-STSGQSSTFDQEGS 1328
            + S +G SS   G    G+GH     + G+   GSG    QG  G   S       +EG+
Sbjct: 306  WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGN 365

Query: 1329 STGQSSSYGHRGSGSS 1344
                 S   +R S +S
Sbjct: 366  RLLGGSGDNYRNSETS 381



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 95/349 (27%), Positives = 139/349 (39%), Gaps = 32/349 (9%)

Query: 1444 GSSSGSSSSYGQHGSGSR--QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGS 1501
            GS        G+  +G+   ++LGHG  G    +    + G+   G+  S      G G+
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75

Query: 1502 GWSSSRGPYE-SGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG 1560
              +   G  +  G   +  LG+R   +  + G   H      +    +HG+ + + S  G
Sbjct: 76   REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQG 134

Query: 1561 QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG----HGQRGSGSR------QSPS 1610
              G +    +S G HG   SQ  G G QG G+    G    HG  G+ +       Q   
Sbjct: 135  VPGHNGAWETSGG-HGIFGSQG-GLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAP 192

Query: 1611 YGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ--HGSGSGHSSGYGQHGS 1668
            +G+ G+G     + G +  G     G+G   +S+      +    GSG G S+  G  GS
Sbjct: 193  WGQGGNGG--PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGS 250

Query: 1669 RSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGS----GLGH 1724
            +SG S  G    +++ SSS     GS S  SSG    GS      SRG  GS    G   
Sbjct: 251  QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSST 310

Query: 1725 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSG 1773
             SS G HG GSG  +   P   + G+ +       GSG S      G G
Sbjct: 311  GSSSGNHG-GSGGGNGHKPGCEKPGNEA------RGSGESGIQGFRGQG 352



 Score = 86.7 bits (213), Expect = 3e-16
 Identities = 96/369 (26%), Positives = 138/369 (37%), Gaps = 42/369 (11%)

Query: 640 GSGSSQSSRYGQQGSGSGQSPSRGRHGSDF---GHSSSYGQHGSGSGWSSSNGPHGSVSG 696
           GSG +   + G++ +G+    + G    D    G   + G+   G+  S  +   G  + 
Sbjct: 17  GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76

Query: 697 QS--------SGFGHKSGSGQSSGYSQHGSGSS-HSSGYR-----KHGSRSGQSSRSEQH 742
           ++         GFG     G   G + H  G++ H  G +     +HG+ + + S     
Sbjct: 77  EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVP 136

Query: 743 GSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSS 802
           G +    +S G    GS    G   QG+  G     V HG     + S G +  G     
Sbjct: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWV-HGYPGNSAGSFGMNPQGAPWG- 194

Query: 803 SCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGR-------HGSTSGQSSSSG 855
                + G+G    FG +  G+    +Q G  S   S+Q          GS  G S+S G
Sbjct: 195 -----QGGNGGPPNFGTNTQGA---VAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246

Query: 856 QHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGS---- 911
              S SG S S    ++ +  +SG    GS SG S G    GS      S G  GS    
Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306

Query: 912 GSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSE 971
           GS   SSSG HG   G   G GHK    +  G    GSG      +   G  S     S+
Sbjct: 307 GSSTGSSSGNHG---GSGGGNGHKPGC-EKPGNEARGSGESGIQGFRGQGVSSNMREISK 362

Query: 972 QHGSSSGSS 980
           +     G S
Sbjct: 363 EGNRLLGGS 371



 Score = 82.0 bits (201), Expect = 8e-15
 Identities = 106/404 (26%), Positives = 149/404 (36%), Gaps = 77/404 (19%)

Query: 1914 GSSSGSSSSYGQHGSGSR--QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGS 1971
            GS        G+  +G+   ++LGHG  G    +    + G+   G+  S      G G+
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75

Query: 1972 GWSSSRGPYE-SGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCG 2030
              +   G  +  G G +  LG+R   +  + G      ++GH            Q+    
Sbjct: 76   REAVGTGVRQVPGFGAADALGNRVGEAAHALG------NTGHE--------IGRQAEDVI 121

Query: 2031 QHGASSGQSSSHGQ--HGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 2088
            +HGA + + S  G   H      S G+G  GS  G   G GQ   G   +P    HG   
Sbjct: 122  RHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLG-GQGQGNPGGLGTPWV--HGYPG 178

Query: 2089 GRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 2148
              + S G +  G     G       +G   ++  +  G+    GYG    R+   + G  
Sbjct: 179  NSAGSFGMNPQGAPWGQG------GNGGPPNFGTNTQGAVAQPGYGS--VRASNQNEGCT 230

Query: 2149 HGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRS 2208
            +   SGS       G GS  S G     SGS  S S G + +GS         GS SG S
Sbjct: 231  NPPPSGS-------GGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG------GSSSG-S 276

Query: 2209 SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGS 2268
            SS G                         S  GS  G   S G  G + G S +    GS
Sbjct: 277  SSGG-------------------------SSGGSSGG---SSGNSGGSRGDSGSESSWGS 308

Query: 2269 STGQSS-SHGQHGSGSSQS---SSYGQQGSGSGQSPSRGRHGSG 2308
            STG SS +HG  G G+         G +  GSG+S  +G  G G
Sbjct: 309  STGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 56/193 (29%), Positives = 79/193 (40%), Gaps = 20/193 (10%)

Query: 132 WSAGEND---SYSRNVRGSL-KPGTESISRRLSFQRDF----------SGQHNSYSGQSS 177
           W  G N    ++  N +G++ +PG  S+  R S Q +            G  NS  G  S
Sbjct: 193 WGQGGNGGPPNFGTNTQGAVAQPGYGSV--RASNQNEGCTNPPPSGSGGGSSNSGGGSGS 250

Query: 178 SYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSS 237
             G   S S+  +  G    GS    + G    GS   SS ++ GS  G S   S   SS
Sbjct: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGS-RGDSGSESSWGSS 309

Query: 238 SGQSSG-YSQHGSGSGHSSGYGQHGSRS-GQSSRGERHRSSSGSSSSYGQ-HGSGSRQSL 294
           +G SSG +   G G+GH  G  + G+ + G    G +     G SS+  +    G+R   
Sbjct: 310 TGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLG 369

Query: 295 GHGRQGSGSRQSP 307
           G G     S  SP
Sbjct: 370 GSGDNYRNSETSP 382


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score =  103 bits (257), Expect = 2e-21
 Identities = 168/820 (20%), Positives = 292/820 (35%), Gaps = 99/820 (12%)

Query: 1290 GSGHSSAYSQHGSGSGHFCS-QGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSG 1348
            GSG      Q  +  G     +GQ G+ +G+ +   Q       +    +RG G  +++ 
Sbjct: 53   GSGDKKLRRQKAAAGGKKARLRGQKGAVAGKEAR--QHWQKAAGAGGAENRGGGEQKAAA 110

Query: 1349 YGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSS 1408
             G    G      R R    +   S   +  +    ++ S   G+G+ +++     +S  
Sbjct: 111  AGTKSLGGRGRKPRRRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQG 170

Query: 1409 WQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGE--RHGSSSGSSSSYGQHGSGSRQ---- 1462
             +     Q  + +G  S   +   R G  SRG+  + G    + S +G+   G R+    
Sbjct: 171  GEKP---QKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRR 227

Query: 1463 ---SLGHGQHGSGSGQSPSPSR--GRHGSGSGQSSSYSPYGSGS------------GWSS 1505
               + G  +   G G+ P   R  G+  +  G+S      G G               + 
Sbjct: 228  PKPAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAK 287

Query: 1506 SRGPYESGSSHSS-GLGHRESRS--GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG-- 1560
             RG   +G   ++ G G R  +S  GQ+  +G+ G             + +G     G  
Sbjct: 288  RRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQ 347

Query: 1561 QHGASSGQSSSHGQHGSGSS----QSSGYGRQGSGSGQSPG--HGQRGSGSRQSPSYGRH 1614
            Q  A  G  S   Q   G      ++S  G +  G G   G    +R    R+ P +   
Sbjct: 348  QKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNP 407

Query: 1615 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 1674
               + ++ ++   G G  +    G   + S           G    SG G+   R GQ +
Sbjct: 408  RRRAQKAPAAKPRGGGSKKPRRRGPKAAKS----------RGGKSRSGGGKKPRRRGQKA 457

Query: 1675 RGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSG 1734
            R +   + + S    G    G +++S  G +  G G     G++    G  +      + 
Sbjct: 458  RQKAAEAGAESR---GDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKAT 514

Query: 1735 SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD 1794
            +  + SRG  + R    +V G      G  S   Q    +G   S G  G+   +    +
Sbjct: 515  AAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGA-TSHGGGGNKQSRGGGGN 573

Query: 1795 QEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGW 1854
            +       +++    G G  Q    G Q + +G + SR    SG G   ++ Q  +G+G 
Sbjct: 574  KPRQWGQTAAAAKTRGGGDKQP---GWQKAAAGVTKSR----SGDGGKKAWRQKAAGTGA 626

Query: 1855 SSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHG 1914
             S       G   ++        +W ++G T  GSG G    +++  +   +SS     G
Sbjct: 627  KSRKKPWRRGQKDAAA----AEKAW-ATGATSRGSG-GKQPRWQKPAAAGSESSAAAAVG 680

Query: 1915 SSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG--------RHGSGSGQSSSYGP 1966
              + +     +  + SR   G G   +  G +P   RG        R G G+    S G 
Sbjct: 681  QEAEARKKPRRRRAKSR---GDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGA 737

Query: 1967 YGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQS 2026
               GSG + SR   ++ +  S G G  + R G            G  S  G+    +G  
Sbjct: 738  KSRGSGGAKSRSGKKAAASKSHGGGGAKRRRG-----------GGAKSRSGEKAVTAG-- 784

Query: 2027 SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 2066
               GQ  A++G     G+         G G++ +  G+ P
Sbjct: 785  ---GQKAAAAG-----GKKPPRVKSRGGRGQKAAAGGKKP 816



 Score = 99.4 bits (246), Expect = 5e-20
 Identities = 163/789 (20%), Positives = 279/789 (35%), Gaps = 80/789 (10%)

Query: 1760 GSGHSSAYSQHGSGSGHFCS-QGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSS 1818
            GSG      Q  +  G     +GQ G+ +G+ +   Q       +      G G  ++++
Sbjct: 53   GSGDKKLRRQKAAAGGKKARLRGQKGAVAGKEAR--QHWQKAAGAGGAENRGGGEQKAAA 110

Query: 1819 YGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSS 1878
             G +  G      R R    +   S   +  +    ++ S   G+G+ +++     +S  
Sbjct: 111  AGTKSLGGRGRKPRRRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKS-- 168

Query: 1879 WQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQH--GSSSGSSSSYGQHGSGSRQ---- 1932
             Q     Q  + +G  S   +   R G  SRG++   G    + S +G+   G R+    
Sbjct: 169  -QGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRR 227

Query: 1933 ---SLGHGQHGSGSGQSPSPSR--GRHGSGSGQSSSYGPYGSGS------------GWSS 1975
               + G  +   G G+ P   R  G+  +  G+S      G G               + 
Sbjct: 228  PKPAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAK 287

Query: 1976 SRGPYESGSGHSS-GLGHRESRS--GQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCG-- 2030
             RG   +G   ++ G G R  +S  GQ+  +G+ G             +A+G     G  
Sbjct: 288  RRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQ 347

Query: 2031 QHGASSGQSSSHGQHGSGSS----QSSGYGRQGSGSGQSPG--HGQRGSGSRQSPSYGRH 2084
            Q  A  G  S   Q   G      ++S  G +  G G   G    +R    R+ P +   
Sbjct: 348  QKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNP 407

Query: 2085 GSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 2144
               + ++ ++   G G  +    G   + S           G    SG G+   R GQ +
Sbjct: 408  RRRAQKAPAAKPRGGGSKKPRRRGPKAAKS----------RGGKSRSGGGKKPRRRGQKA 457

Query: 2145 RGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSG 2204
            R  +  + +G+ SR G    G +++S  G +  G G     G++    G  +      + 
Sbjct: 458  R--QKAAEAGAESR-GDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKAT 514

Query: 2205 SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD 2264
            +  + SRG  + R    +V G      G  S   Q    +G   S G  G+   +    +
Sbjct: 515  AAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGA-TSHGGGGNKQSRGGGGN 573

Query: 2265 QEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGW 2324
            +       +++    G G  Q    G Q + +G + SR    SG G   ++ Q  +G+G 
Sbjct: 574  KPRQWGQTAAAAKTRGGGDKQP---GWQKAAAGVTKSR----SGDGGKKAWRQKAAGTGA 626

Query: 2325 SSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHG 2384
             S       G   ++        +W ++G T  GSG G    +++  +   +SS     G
Sbjct: 627  KSRKKPWRRGQKDAAA----AEKAW-ATGATSRGSG-GKQPRWQKPAAAGSESSAAAAVG 680

Query: 2385 SSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSP----------SPSRGRHGSGSGQSSSY 2434
              + +     +  + SR   G G   +  G +P            SRG  G+ S  S   
Sbjct: 681  QEAEARKKPRRRRAKSR---GDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGA 737

Query: 2435 SPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSG 2494
               GSG   S S     +   H  G   R    G  S  G+   ++G        G    
Sbjct: 738  KSRGSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAKSRSGEKAVTAGGQKAAAAGGKKPP 797

Query: 2495 QSSSCGQHG 2503
            +  S G  G
Sbjct: 798  RVKSRGGRG 806



 Score = 98.6 bits (244), Expect = 8e-20
 Identities = 176/859 (20%), Positives = 307/859 (35%), Gaps = 90/859 (10%)

Query: 548  HESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSS------GLGHQESRSGQSSGYGQHG 601
            H   ++ +   GP G   G + +R P E  +  ++        G +   SG      Q  
Sbjct: 6    HRQCNQAAGRAGP-GAPLGAALARTPVELAAESAAPALSAAAAGVKILGSGDKKLRRQKA 64

Query: 602  SSSGHSST-HGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQG-SGSGQS 659
            ++ G  +   GQ G+ +G+ +   QH   +  +      G G  +++  G +   G G+ 
Sbjct: 65   AAGGKKARLRGQKGAVAGKEAR--QHWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRGRK 122

Query: 660  PSR-GRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGS 718
            P R G+  +  G      +    +   S N   G+    ++  G KS  G+    +    
Sbjct: 123  PRRRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAA-GVKSQGGEKPQKAAAAG 181

Query: 719  GSSHSSGYRKHGSRSGQSSRSEQH--GSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSP 776
              S S    K   R G  SR ++   G      S +G+   G  +   H R    +G + 
Sbjct: 182  AKSRSG---KKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKK--HRRPKPAAGGAK 236

Query: 777  SRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASG 836
            SR   G         GQ              ++ +G  S  G+   G  +   + G  + 
Sbjct: 237  SRRGGGKKPQKQRRRGQ--------------KAATGGKSRVGKSRGGGDKKLRRQGQNAA 282

Query: 837  HFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQR 896
               ++ R  +T+G+  ++ +     G  S  GQ+           R G  + ++   G +
Sbjct: 283  LAGAKRRGAATAGEKPAA-KGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTK 341

Query: 897  GSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQ-HGSGSGHSS 955
              G GQ  +         +    G+       S+        G   G  +    G G   
Sbjct: 342  RGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKK 401

Query: 956  SYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP--SRGR 1013
               Q+  R  Q + + +     G S    + G  + +S G G+  SG G+ P     + R
Sbjct: 402  PRWQNPRRRAQKAPAAK--PRGGGSKKPRRRGPKAAKSRG-GKSRSGGGKKPRRRGQKAR 458

Query: 1014 HGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQ-SSGYGQHGSSSGH 1072
              +    + S G  + G   +S+ G    G G  S  G    R GQ +   G+  +++G 
Sbjct: 459  QKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKATAAGA 518

Query: 1073 SS------------THGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQS-SGYGRQG 1119
             S              G      G  S   Q   ++G ++SHG  G G+ QS  G G + 
Sbjct: 519  KSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAG-ATSHG--GGGNKQSRGGGGNKP 575

Query: 1120 SGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRS-SSSGQHGSGLGESSGFGHHESSS---- 1174
               GQ+    +   G  + P + +  +G  +S S  G   +   +++G G          
Sbjct: 576  RQWGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGAKSRKKPWRR 635

Query: 1175 GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSR------- 1227
            GQ  + +   + +  ++  G  G +  +  +    GS S +++  GQ     +       
Sbjct: 636  GQKDAAAAEKAWATGATSRGS-GGKQPRWQKPAAAGSESSAAAAVGQEAEARKKPRRRRA 694

Query: 1228 QSSGHGRQGSGSGHSP-SRGRHGSGLGHSSSHG---QHGSGSGRSSSRGPYESRSGHSSV 1283
            +S G G Q +  G +P  R      LG S   G     GSG  +S   G  +SRSG  + 
Sbjct: 695  KSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKSRSGKKAA 754

Query: 1284 FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGS 1343
              +   G G     ++   G G     G+   T+G      Q+ ++ G     G +    
Sbjct: 755  ASKSHGGGG-----AKRRRGGGAKSRSGEKAVTAG-----GQKAAAAG-----GKKPPRV 799

Query: 1344 SQSSGYGRHGAGSGQSPSR 1362
                G G+  A  G+ P R
Sbjct: 800  KSRGGRGQKAAAGGKKPLR 818



 Score = 98.2 bits (243), Expect = 1e-19
 Identities = 169/762 (22%), Positives = 281/762 (36%), Gaps = 92/762 (12%)

Query: 2010 SGHSSTHGQHGSASGQSSSC-GQHGASSGQSS-SHGQH--GSGSSQSSGYGRQGSGSGQS 2065
            SG      Q  +A G+ +   GQ GA +G+ +  H Q   G+G +++ G G Q + +  +
Sbjct: 54   SGDKKLRRQKAAAGGKKARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAAAAGT 113

Query: 2066 PGHGQRGSGSRQSPSYGRHGSGSG---------RSSSSGQHGPGLGESSGFGHHESSSGQ 2116
               G RG   R+    G+  + +G         +S+++G    G G           S Q
Sbjct: 114  KSLGGRGRKPRRR---GQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKS-Q 169

Query: 2117 SSSYSQHGSGSGHSSGYGQHGSRSGQSSRGE--RHGSSSGSSSRYGQHGSGSRQ------ 2168
                 Q  + +G  S  G+   R G  SRG+  + G    + SR+G+   G R+      
Sbjct: 170  GGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPK 229

Query: 2169 -SSGHGRQGSGSGHSPS----RGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGH--- 2220
             ++G  +   G G  P     RG+  +  G S      G G  +   +G   + +G    
Sbjct: 230  PAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRR 289

Query: 2221 -SSVFGQHES-----GSGHSSAYSQH---GSGSGHFCSQGQHGSTSGQSSTF-----DQE 2266
             ++  G+  +     G G  S   Q+   G G      +GQ  + +  + T       Q+
Sbjct: 290  GAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQK 349

Query: 2267 GSSTGQSSSHGQHGSGSS----QSSSYGQQGSGSGQSPS-RGRHGSGSGHSSSYGQHGSG 2321
             +  G  S   Q   G      ++S+ G +  G G     R     G G      Q+   
Sbjct: 350  AAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRR 409

Query: 2322 SGWSSSSGR-HGSGSGQSSGFGHHESSSWQSSGYTQHGSGSG---HSSSYEQHGSRSGQS 2377
                + + +  G GS +    G   + S    G ++ G G           Q  + +G  
Sbjct: 410  RAQKAPAAKPRGGGSKKPRRRGPKAAKS--RGGKSRSGGGKKPRRRGQKARQKAAEAGAE 467

Query: 2378 SRGER-HGSSSGSSSSYGQHGSGSRQSLG-----HGQHGSGSGQSPSPSRGRHGSGSGQS 2431
            SRG++  G    S++     G G +   G      GQ    +G+  + + G    G  Q 
Sbjct: 468  SRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKATAA-GAKSRGRKQP 526

Query: 2432 SSYSPYGSGS----GWSSSRGPYES---GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 2484
                P  +G+    G S SR   ++   G+    G G+++SR G  +   Q G ++  + 
Sbjct: 527  RRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSRGGGGNKPRQWGQTAAAAK 586

Query: 2485 THGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGH-GQRGS 2543
            T G      G     G   A++G + S    G   +        G+ S + P   GQ+ +
Sbjct: 587  TRG------GGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGAKSRKKPWRRGQKDA 640

Query: 2544 GSRQSP-SYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 2602
             + +   + G    GSG      Q  +  G  S          ++    +         G
Sbjct: 641  AAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEARKKPRRRRAKSRGDG 700

Query: 2603 YGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL 2662
             GQ+ +     +  +R G         G  G+ SR S G   +GSG  +S    R G   
Sbjct: 701  -GQNAAVG--INPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKS----RSGKKA 753

Query: 2663 GHSSSHGQHGSGSGRSSSRGPYESRLGHSSVF--GQHESGSG 2702
              S SHG  G G+ R    G  +SR G  +V   GQ  + +G
Sbjct: 754  AASKSHG--GGGAKRRRGGGA-KSRSGEKAVTAGGQKAAAAG 792



 Score = 97.8 bits (242), Expect = 1e-19
 Identities = 169/762 (22%), Positives = 280/762 (36%), Gaps = 92/762 (12%)

Query: 1070 SGHSSTHGQHGSTSGQSSSC-GQHGASSGQSS-SHGQH--GSGSSQSSGYGRQGSGSGQS 1125
            SG      Q  +  G+ +   GQ GA +G+ +  H Q   G+G +++ G G Q + +  +
Sbjct: 54   SGDKKLRRQKAAAGGKKARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAAAAGT 113

Query: 1126 PGHGQRGSGSRQSPSYGRHGSGSG---------RSSSSGQHGSGLGESSGFGHHESSSGQ 1176
               G RG   R+    G+  + +G         +S+++G    G G           S Q
Sbjct: 114  KSLGGRGRKPRRR---GQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKS-Q 169

Query: 1177 SSSYSQHGSGSGHSSGYGQHGSRSGQSSRGE--RHGSSSGSSSHYGQHGSGSRQ------ 1228
                 Q  + +G  S  G+   R G  SRG+  + G    + S +G+   G R+      
Sbjct: 170  GGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPK 229

Query: 1229 -SSGHGRQGSGSGHSPS----RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGH--- 1280
             ++G  +   G G  P     RG+  +  G S      G G  +   +G   + +G    
Sbjct: 230  PAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRR 289

Query: 1281 -SSVFGQHES-----GSGHSSAYSQH---GSGSGHFCSQGQHGSTSGQSSTF-----DQE 1326
             ++  G+  +     G G  S   Q+   G G      +GQ  + +  + T       Q+
Sbjct: 290  GAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQK 349

Query: 1327 GSSTGQSSSYGHRGSGSS----QSSGYGRHGAGSGQSPS-RGRHGSGSGHSSSYGQHGSG 1381
             +  G  S    R  G      ++S  G    G G     R     G G      Q+   
Sbjct: 350  AAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRR 409

Query: 1382 SGWSSSSGR-HGSGSGQSSGFGHHESSSWQSSGCTQHGSGSG---HSSSYEQHGSRSGQS 1437
                + + +  G GS +    G   + S    G ++ G G           Q  + +G  
Sbjct: 410  RAQKAPAAKPRGGGSKKPRRRGPKAAKS--RGGKSRSGGGKKPRRRGQKARQKAAEAGAE 467

Query: 1438 SRGER-HGSSSGSSSSYGQHGSGSRQSLG-----HGQHGSGSGQSPSPSRGRHGSGSGQS 1491
            SRG++  G    S++     G G +   G      GQ    +G+  + + G    G  Q 
Sbjct: 468  SRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKATAA-GAKSRGRKQP 526

Query: 1492 SSYSPYGSGS----GWSSSRGPYES---GSSHSSGLGHRESRSGQSSGYGQHGSSSGHSS 1544
                P  +G+    G S SR   ++   G++   G G+++SR G  +   Q G ++  + 
Sbjct: 527  RRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSRGGGGNKPRQWGQTAAAAK 586

Query: 1545 THGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGH-GQRGS 1603
            T G      G     G   A++G + S    G   +        G+ S + P   GQ+ +
Sbjct: 587  TRG------GGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGAKSRKKPWRRGQKDA 640

Query: 1604 GSRQSP-SYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 1662
             + +   + G    GSG      Q  +  G  S          ++    +         G
Sbjct: 641  AAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEARKKPRRRRAKSRGDG 700

Query: 1663 YGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL 1722
             GQ+ +     +  +R G   R     G  G+ SR S G   +GSG  +S    R G   
Sbjct: 701  -GQNAAVG--INPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKS----RSGKKA 753

Query: 1723 GHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF--GQHESGSG 1762
              S SHG  G G+ R    G  +SRSG  +V   GQ  + +G
Sbjct: 754  AASKSHG--GGGAKRRRGGGA-KSRSGEKAVTAGGQKAAAAG 792



 Score = 97.8 bits (242), Expect = 1e-19
 Identities = 171/762 (22%), Positives = 286/762 (37%), Gaps = 92/762 (12%)

Query: 1540 SGHSSTHGQHGSTSGQSSSC-GQHGASSGQSS-SHGQH--GSGSSQSSGYGRQGSGSGQS 1595
            SG      Q  +  G+ +   GQ GA +G+ +  H Q   G+G +++ G G Q + +  +
Sbjct: 54   SGDKKLRRQKAAAGGKKARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAAAAGT 113

Query: 1596 PGHGQRGSGSRQSPSYGRHGSGSG---------RSSSSGQHGSGLGESSGFGHHESSSGQ 1646
               G RG   R+    G+  + +G         +S+++G    G G           S Q
Sbjct: 114  KSLGGRGRKPRRR---GQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKS-Q 169

Query: 1647 SSSYSQHGSGSGHSSGYGQHGSRSGQSSRGE--RHGSSSRSSSRYGQHGSGSRQ------ 1698
                 Q  + +G  S  G+   R G  SRG+  + G    + SR+G+   G R+      
Sbjct: 170  GGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPK 229

Query: 1699 -SSGHGRQGSGSGQSPS----RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGH--- 1750
             ++G  +   G G+ P     RG+  +  G S      G G  +   +G   + +G    
Sbjct: 230  PAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRR 289

Query: 1751 -SSVFGQHES-----GSGHSSAYSQH---GSGSGHFCSQGQHGSTSGQSSTF-----DQE 1796
             ++  G+  +     G G  S   Q+   G G      +GQ  + +  + T       Q+
Sbjct: 290  GAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQK 349

Query: 1797 GSSTGQSSSHGQHGSGSS----QSSSYGQQGSGSGQSPS-RGRHGSGSGHSSSYGQHGSG 1851
             +  G  S   Q   G      ++S+ G +  G G     R     G G      Q+   
Sbjct: 350  AAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRR 409

Query: 1852 SGWSSSSGR-HGSGSGQSSGFGHHESSSWQSSGYTQHGSGSG---HSSSYEQHGSRSGQS 1907
                + + +  G GS +    G   + S    G ++ G G           Q  + +G  
Sbjct: 410  RAQKAPAAKPRGGGSKKPRRRGPKAAKS--RGGKSRSGGGKKPRRRGQKARQKAAEAGAE 467

Query: 1908 SRGE-----QHGSSSGSSSSYGQHGSGSRQSLGH-GQHGSGSGQSPSPSRGRHGSGSGQS 1961
            SRG+     Q  S++G+ S  G   S S ++L   GQ    +G+  + + G    G  Q 
Sbjct: 468  SRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKATAA-GAKSRGRKQP 526

Query: 1962 SSYGPYGSGS----GWSSSRGPYES---GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 2014
                P  +G+    G S SR   ++   G+    G G+++SR G  +   Q G ++  + 
Sbjct: 527  RRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSRGGGGNKPRQWGQTAAAAK 586

Query: 2015 THGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGH-GQRGS 2073
            T G      G     G   A++G + S    G   +        G+ S + P   GQ+ +
Sbjct: 587  TRG------GGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGAKSRKKPWRRGQKDA 640

Query: 2074 GSRQSP-SYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 2132
             + +   + G    GSG      Q     G  S          ++    +         G
Sbjct: 641  AAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEARKKPRRRRAKSRGDG 700

Query: 2133 YGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGS 2192
             GQ+ +     +  +R G         G  G+ SR S G   +GSG     ++ R G  +
Sbjct: 701  -GQNAAVG--INPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGG----AKSRSGKKA 753

Query: 2193 GHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF--GQHESGSG 2232
              S SHG  G G+ R    G  +SRSG  +V   GQ  + +G
Sbjct: 754  AASKSHG--GGGAKRRRGGGA-KSRSGEKAVTAGGQKAAAAG 792



 Score = 97.4 bits (241), Expect = 2e-19
 Identities = 180/837 (21%), Positives = 306/837 (36%), Gaps = 114/837 (13%)

Query: 376  QHGSTSGQASSSGQHGSSSRQSSSYGQHESASR--HSSGRGQHSSGSGQSPGHGQRGSGS 433
            Q    +G+A      G++  ++      ESA+    ++  G    GSG      Q+ +  
Sbjct: 8    QCNQAAGRAGPGAPLGAALARTPVELAAESAAPALSAAAAGVKILGSGDKKLRRQKAAAG 67

Query: 434  GQSPS-SGQHGTGFGRSSSSG-PYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGH 491
            G+     GQ G   G+ +       +G+G +   G  E  +  ++G    G         
Sbjct: 68   GKKARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAA-AAGTKSLGGRGRKPRRR 126

Query: 492  GQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESG 551
            GQ  + +G      R   SA + S     G+G++++   +   S  G+ P  +     +G
Sbjct: 127  GQKAAATGSKKPRWRAQKSAAAGSK--NRGAGAQKAAAAAGVKSQGGEKPQKAAA---AG 181

Query: 552  SRQSSSYGPHGYGSGRSSSRGPYES-GSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTH 610
            ++  S   P   G+    SRG  +  G    +     ++R G+   + +   ++G + + 
Sbjct: 182  AKSRSGKKPRRRGA---KSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPKPAAGGAKSR 238

Query: 611  GQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFG 670
               G    +    GQ  AT G+S      G G  +  R GQ  + +G   ++ R  +  G
Sbjct: 239  RGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAG---AKRRGAATAG 295

Query: 671  HS-SSYGQHGSGSGWSSSNGPHGSVSGQS-SGFGHKSGSGQSSGYSQHGSGSSHSS---- 724
               ++ G+ G G        P     G+     G K+    ++G  + G G   ++    
Sbjct: 296  EKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGV 355

Query: 725  GYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSS--GHGRQGSGSGHSPSRVRHG 782
              RK   R G+  R  Q  S++G  S  G    G  ++   G GR+     +   R +  
Sbjct: 356  KSRKKQRRRGKKPR-RQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKA 414

Query: 783  SSS---GHSSSHGQHGSGTSCSSSCGHYESGSG------------QASGFGQHESGSGQG 827
             ++   G  S   +     +  S  G   SG G            +A+  G    G  + 
Sbjct: 415  PAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQ 474

Query: 828  YSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGS 887
              Q  SA+G  S  G      G  S SG++    GQ +     ++ +  A  RGR     
Sbjct: 475  GRQKASAAGTKSRGG------GLKSHSGKNLWRRGQKAEAAGEKATAAGAKSRGRK-QPR 527

Query: 888  GQSPGHGQRGSGSGQSPSYGR----------HGSGSGRSSSSG--------RHGSGSGQS 929
             Q P      S  G S S  R          HG G  + S  G           + + ++
Sbjct: 528  RQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSRGGGGNKPRQWGQTAAAAKT 587

Query: 930  SGFGHKSSSGQ--SSGYTQHGSGSGHSSSYEQHGSRSGQSSRSE--QHGSSSGSSSSYG- 984
             G G K    Q  ++G T+  SG G   ++ Q  + +G  SR +  + G    +++    
Sbjct: 588  RGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGAKSRKKPWRRGQKDAAAAEKAW 647

Query: 985  -----QHGSGSRQSLGHGQHGSGSGQS--------------PSPSRGRHGSGSGQSSSYG 1025
                   GSG +Q        +GS  S              P   R +     GQ+++ G
Sbjct: 648  ATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEARKKPRRRRAKSRGDGGQNAAVG 707

Query: 1026 --PYR-----------SGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ-HGSSSG 1071
              P++            G G + SRG   SG   S G G  +SRSG+ +   + HG    
Sbjct: 708  INPWQRRGKKPRLGKSRGGGGAKSRG---SGGAKSRGSGGAKSRSGKKAAASKSHGGGGA 764

Query: 1072 HSSTHGQHGSTSGQS--SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 1126
                 G   S SG+   ++ GQ  A++G     G+         G G++ +  G+ P
Sbjct: 765  KRRRGGGAKSRSGEKAVTAGGQKAAAAG-----GKKPPRVKSRGGRGQKAAAGGKKP 816



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 160/769 (20%), Positives = 269/769 (34%), Gaps = 111/769 (14%)

Query: 1890 GSGHSSSYEQHGSRSGQSSRGE-QHGSSSGSSSSYGQH-----GSGSRQSLGHG-QHGSG 1942
            GSG      Q  +  G+ +R   Q G+ +G  +   QH     G+G  ++ G G Q  + 
Sbjct: 53   GSGDKKLRRQKAAAGGKKARLRGQKGAVAGKEAR--QHWQKAAGAGGAENRGGGEQKAAA 110

Query: 1943 SGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2002
            +G      RGR     GQ ++     +GS     R    + +G S   G    ++  ++G
Sbjct: 111  AGTKSLGGRGRKPRRRGQKAA----ATGSKKPRWRAQKSAAAG-SKNRGAGAQKAAAAAG 165

Query: 2003 YGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS 2062
                G          Q  +A+G  S  G+     G + S G       Q     R G   
Sbjct: 166  VKSQGGEKP------QKAAAAGAKSRSGKKPRRRG-AKSRGDEDKKGRQREAKSRFGKTR 218

Query: 2063 GQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQ 2122
            G     G+R    R  P+     +G  +S   G   P   +    G   ++ G+S     
Sbjct: 219  G-----GRRKKHRRPKPA-----AGGAKSRRGGGKKPQ--KQRRRGQKAATGGKSRVGKS 266

Query: 2123 HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHS 2182
             G G       GQ+ + +G   RG        ++   G+ G G +   G   +    G  
Sbjct: 267  RGGGDKKLRRQGQNAALAGAKRRGAATAGEKPAAK--GRGGRGPKSLGGQNPRWGRGGKK 324

Query: 2183 PSRGRHGSGSGHSSSHGQHGSGSGRSSS-------------RGPYESRSGHSSVFGQHES 2229
            P R   G  +  +++ G    G G+  +             RG    R   S+   +   
Sbjct: 325  PRR--RGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRG 382

Query: 2230 GSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSY 2289
            G            G G    + Q+     Q +         G  S   +     +  S  
Sbjct: 383  GGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAP---AAKPRGGGSKKPRRRGPKAAKSRG 439

Query: 2290 GQQGSGSGQSPSR----GRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHE 2345
            G+  SG G+ P R     R  +    + S G    G   +S++G    G G  S   H  
Sbjct: 440  GKSRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLKS---HSG 496

Query: 2346 SSSWQSSGYTQHGSGSGHSSSYEQHG---------------SRSGQSSRGERHGSSSGSS 2390
             + W+     +       ++  +  G               SR G S   +R  + +  +
Sbjct: 497  KNLWRRGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGA 556

Query: 2391 SSYGQHGSGSRQSLGHGQHGSGS-GQSPSPSRGRHG------------------SGSGQS 2431
            +S+G  G G++QS G G +     GQ+ + ++ R G                  SG G  
Sbjct: 557  TSHG--GGGNKQSRGGGGNKPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGK 614

Query: 2432 SSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS 2491
             ++    +G+G  S + P+  G   ++      +    S G    G            GS
Sbjct: 615  KAWRQKAAGTGAKSRKKPWRRGQKDAAAAEKAWATGATSRG---SGGKQPRWQKPAAAGS 671

Query: 2492 TSGQSSSCGQHGASSGQ-----SSSHGQHGSGSSQS-SGYGRQGSGS--GQSPGHG---Q 2540
             S  +++ GQ   +  +     + S G  G  ++   + + R+G     G+S G G    
Sbjct: 672  ESSAAAAVGQEAEARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKS 731

Query: 2541 RGSGSRQSPSYGRHGSGSG-RSSSSGQHGSGLGESSGFGHHESSSGQSS 2588
            RGSG  +S   G   S SG ++++S  HG G  +    G  +S SG+ +
Sbjct: 732  RGSGGAKSRGSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAKSRSGEKA 780



 Score = 81.6 bits (200), Expect = 1e-14
 Identities = 154/731 (21%), Positives = 260/731 (35%), Gaps = 79/731 (10%)

Query: 98  GSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISR 157
           G + R    + Q+      K+   R + S +  S + G     +    G    G E   +
Sbjct: 117 GGRGRKPRRRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQK 176

Query: 158 RLSF-QRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCG-SGSGQSPNYGQHGSGSGQS 215
             +   +  SG+     G + S G+++    Q   + + G +  G+   + +    +G +
Sbjct: 177 AAAAGAKSRSGKKPRRRG-AKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPKPAAGGA 235

Query: 216 SSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRS 275
            S    G    +     Q  ++ G+S      G G       GQ+ + +G   RG     
Sbjct: 236 KSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAG 295

Query: 276 SSGSSSSYGQHGSGS--RQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQH------GS 327
              ++   G  G  S   Q+   GR G   R+        + +G     G        G 
Sbjct: 296 EKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGV 355

Query: 328 GSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSK-HGSGSGHSSSQGQHGSTSGQ-AS 385
            S     R   +    + S  G    G G   G  +    G G    + Q+     Q A 
Sbjct: 356 KSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAP 415

Query: 386 SSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSP-GHGQRG---SGSGQSPSSGQ 441
           ++   G  S++    G   + SR     G+  SG G+ P   GQ+    +    + S G 
Sbjct: 416 AAKPRGGGSKKPRRRGPKAAKSR----GGKSRSGGGKKPRRRGQKARQKAAEAGAESRGD 471

Query: 442 HGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQS 501
              G  ++S++G    G G  S    H   +    G     +        G+  + +G  
Sbjct: 472 KKQGRQKASAAGTKSRGGGLKS----HSGKNLWRRGQKAEAA--------GEKATAAGAK 519

Query: 502 SRGERQ-----GSSAGSSSSYGQHGSGSRQ-----SLGHSRHGSGSGQSPSPSRGRHESG 551
           SRG +Q      + AG+ S  G  GS SRQ     + G + HG G  +    SRG   + 
Sbjct: 520 SRGRKQPRRQKPAVAGAKSRVG--GSKSRQRQKAVAAGATSHGGGGNKQ---SRGGGGNK 574

Query: 552 SRQSSSYGPHGYGSGRSSSRGPYESGSG-HSSGLGHQESRSGQSSGYGQHGSSSGHSSTH 610
            RQ       G  +  + +RG  +   G   +  G  +SRSG          ++G  +  
Sbjct: 575 PRQ------WGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGAKS 628

Query: 611 GQHGSTSGQSSSCGQHGATSGQSSSHGQ------------HGSGSSQSSRYGQQGSGSGQ 658
            +     GQ  +     A +  ++S G              GS SS ++  GQ+   + +
Sbjct: 629 RKKPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAE-ARK 687

Query: 659 SPSRGRHGS--DFGHSSSYG-----QHGSGSGWSSSNGPHGSVSGQSSGFGHK-SGSGQS 710
            P R R  S  D G +++ G     + G       S G  G+ S  S G   + SG  +S
Sbjct: 688 KPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKS 747

Query: 711 SGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSG---LSSSYGQHGSGSHQSSGHGR 767
               +  +  SH  G  K     G  SRS +   ++G    +++ G+         G G+
Sbjct: 748 RSGKKAAASKSHGGGGAKRRRGGGAKSRSGEKAVTAGGQKAAAAGGKKPPRVKSRGGRGQ 807

Query: 768 QGSGSGHSPSR 778
           + +  G  P R
Sbjct: 808 KAAAGGKKPLR 818



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 156/797 (19%), Positives = 276/797 (34%), Gaps = 109/797 (13%)

Query: 287  GSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSS-SHGQHGSGSSYSYSRGHYE-----S 340
            GSG ++ L   +  +G +++    + G+ +G  +  H Q  +G+  + +RG  E     +
Sbjct: 53   GSGDKK-LRRQKAAAGGKKARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAAAA 111

Query: 341  GSGQTSGFGQHESGSGQ------------------SSGYSKHGSGSGHSSS----QGQHG 378
            G+    G G+     GQ                  ++G    G+G+  +++    + Q G
Sbjct: 112  GTKSLGGRGRKPRRRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGG 171

Query: 379  STSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPS 438
                +A+++G    S ++    G          GR + +         G+R       P+
Sbjct: 172  EKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPKPA 231

Query: 439  SGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRS 498
            +G  G    R     P           G   ++   S      G G       GQ+ + +
Sbjct: 232  AG--GAKSRRGGGKKPQKQRRR-----GQKAATGGKSRVGKSRGGGDKKLRRQGQNAALA 284

Query: 499  GQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRG------------ 546
            G   RG    ++AG   +    G    +SLG      G G      RG            
Sbjct: 285  GAKRRG---AATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTK 341

Query: 547  RHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQ-HGSSSG 605
            R   G ++++  G       R   + P       +S  G +    G   G  +      G
Sbjct: 342  RGGGGQQKAAVVGVKSRKKQRRRGKKPRRQ---KASAAGAKSRGGGDKKGLREAKRRGDG 398

Query: 606  HSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSR--- 662
                  Q+     Q +   +     G  S   +     +  SR G+  SG G+ P R   
Sbjct: 399  RKKPRWQNPRRRAQKAPAAK---PRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQ 455

Query: 663  -GRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQS---SGYSQHGS 718
              R  +    + S G    G   +S+ G       +S G G KS SG++    G     +
Sbjct: 456  KARQKAAEAGAESRGDKKQGRQKASAAGT------KSRGGGLKSHSGKNLWRRGQKAEAA 509

Query: 719  G-SSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQH-------GSGSHQSSGHGRQGS 770
            G  + ++G +  G +  +  +    G+ S +  S  +        G+ SH   G+ +   
Sbjct: 510  GEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSRG 569

Query: 771  GSGHSPSRVRHGSSSGHSSSHGQHGSG-TSCSSSCGHYESGSGQASGFGQHESGSG---- 825
            G G+ P +    +++  +   G    G    ++      SG G    + Q  +G+G    
Sbjct: 570  GGGNKPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGAKSR 629

Query: 826  -----QGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSS----YGQHESA--- 873
                 +G     +A   +++ G     SG      Q  +++G  SS     GQ   A   
Sbjct: 630  KKPWRRGQKDAAAAEKAWAT-GATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEARKK 688

Query: 874  --SHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSG 931
                 A  RG  G  +       QR    G+ P  G+   G G  S     GSG  +S G
Sbjct: 689  PRRRRAKSRGDGGQNAAVGINPWQR---RGKKPRLGKSRGGGGAKS----RGSGGAKSRG 741

Query: 932  F-GHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGS 990
              G KS SG+ +  ++   G G  +   + G    +S           ++++ G+     
Sbjct: 742  SGGAKSRSGKKAAASKSHGGGG--AKRRRGGGAKSRSGEKAVTAGGQKAAAAGGKKPPRV 799

Query: 991  RQSLGHGQHGSGSGQSP 1007
            +   G GQ  +  G+ P
Sbjct: 800  KSRGGRGQKAAAGGKKP 816



 Score = 75.9 bits (185), Expect = 5e-13
 Identities = 121/602 (20%), Positives = 215/602 (35%), Gaps = 61/602 (10%)

Query: 2230 GSGHSSAYSQHGSGSGHFCS-QGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSS 2288
            GSG      Q  +  G     +GQ G+ +G+ +   Q       +      G G  ++++
Sbjct: 53   GSGDKKLRRQKAAAGGKKARLRGQKGAVAGKEAR--QHWQKAAGAGGAENRGGGEQKAAA 110

Query: 2289 YGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSS 2348
             G +  G      R R    +   S   +  +    ++ S   G+G+ +++     +S  
Sbjct: 111  AGTKSLGGRGRKPRRRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKS-- 168

Query: 2349 WQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGE--RHGSSSGSSSSYGQHGSGSRQ---- 2402
             Q     Q  + +G  S   +   R G  SRG+  + G    + S +G+   G R+    
Sbjct: 169  -QGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRR 227

Query: 2403 ---SLGHGQHGSGSGQSPSPSR--GRHGSGSGQSSSYSPYGSGS------------GWSS 2445
               + G  +   G G+ P   R  G+  +  G+S      G G               + 
Sbjct: 228  PKPAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAK 287

Query: 2446 SRGPYESGSGHSS-GLGHRESRS--GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG-- 2500
             RG   +G   ++ G G R  +S  GQ+  +G+ G             + +G     G  
Sbjct: 288  RRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQ 347

Query: 2501 QHGASSGQSSSHGQHGSGSS----QSSGYGRQGSGSGQSPG--HGQRGSGSRQSPSYGRH 2554
            Q  A  G  S   Q   G      ++S  G +  G G   G    +R    R+ P +   
Sbjct: 348  QKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNP 407

Query: 2555 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 2614
               + ++ ++   G G  +    G   + S           G    SG G+   R GQ +
Sbjct: 408  RRRAQKAPAAKPRGGGSKKPRRRGPKAAKS----------RGGKSRSGGGKKPRRRGQKA 457

Query: 2615 RGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSG 2674
            R  +  + +G+ S  G    G +++S  G +  G G     G++    G  +      + 
Sbjct: 458  R--QKAAEAGAESR-GDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKAT 514

Query: 2675 SGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD 2734
            +  + SRG  + R    +V G      G  S   Q    +G   S G  G+   +     
Sbjct: 515  AAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAG-ATSHGGGGNKQSRGGG-G 572

Query: 2735 QEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQ 2794
             +    GQ+++      G  +  G+ +  AG  +S       SG G   ++ Q  +G+G 
Sbjct: 573  NKPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVTKS------RSGDGGKKAWRQKAAGTGA 626

Query: 2795 SS 2796
             S
Sbjct: 627  KS 628


>gi|33504489 dermokine isoform 2 precursor [Homo sapiens]
          Length = 476

 Score =  102 bits (255), Expect = 4e-21
 Identities = 106/354 (29%), Positives = 148/354 (41%), Gaps = 49/354 (13%)

Query: 1630 GLGESSGFGHHESSSGQSSSYSQ-HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSR 1688
            G GE+      E S+G +   +  HG G   S G G+   +    + G      S+ S  
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAG------SKVSEA 70

Query: 1689 YGQHGSGSRQSSGHG-RQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGS--------GRSS 1739
             GQ   G+R++ G G RQ  G G + + G       H+  +  H  G         G  +
Sbjct: 71   LGQ---GTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADA 127

Query: 1740 SRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS------GHFCSQGQHGSTSGQSSTF 1793
             RG ++   GH+   G  E+  GH    SQ G G       G   +   HG     + +F
Sbjct: 128  VRGSWQGVPGHN---GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSF 184

Query: 1794 --DQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSG 1851
              + +G+  GQ  + G    G++   +  Q G GS ++ ++    +    S      GSG
Sbjct: 185  GMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS------GSG 238

Query: 1852 SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGE 1911
             G S+S G  GS SG SSG G        S+G   +GS SG SSS    G  SG SS G 
Sbjct: 239  GGSSNSGGGSGSQSG-SSGSG--------SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGS 289

Query: 1912 --QHGSSSGSSSSYGQHGSGSRQSLG-HGQHGSGSGQSPSPSR-GRHGSGSGQS 1961
                G S G S S    GS +  S G HG  G G+G  P   + G    GSG+S
Sbjct: 290  SGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGES 343



 Score =  102 bits (254), Expect = 5e-21
 Identities = 123/485 (25%), Positives = 174/485 (35%), Gaps = 49/485 (10%)

Query: 1576 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ-SPSYGRHGSGSGRSSSSGQHGSGLGES 1634
            G      SG    G+  G++ GHG   + S     + G+   G+  S  S   G G  E+
Sbjct: 19   GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78

Query: 1635 SGFGHHESSS-GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQ-- 1691
             G G  +    G + +       + H+ G   H     Q+    RHG+ +   S  G   
Sbjct: 79   VGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGVPG 137

Query: 1692 HGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHS 1751
            H      S GHG  GS  G       +  GLG    HG  G+ +G S    P  +  G  
Sbjct: 138  HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG-SFGMNPQGAPWGQG 196

Query: 1752 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ-------HGSTSGQSSTFDQEGSSTGQSS 1804
               G    G+    A +Q G GS    +Q +        GS  G S++    GS +G S 
Sbjct: 197  GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG 256

Query: 1805 SHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSS-SYGQHGSGSGWSSSSGRHGS 1863
            S G +G  ++ SSS G     S    S G  G  SG+S  S G  GS S W SS+G    
Sbjct: 257  S-GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG---- 311

Query: 1864 GSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRS-GQSSRGEQHGSSSGSSSS 1922
                 S  G+H  S          G G+GH    E+ G+ + G    G Q+  +S    +
Sbjct: 312  -----SSSGNHGGS----------GGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFN 356

Query: 1923 YGQHGSGSRQSLGH-GQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYE 1981
            +       +  LG          Q P PS       S     +        W +      
Sbjct: 357  FDTFWKNFKSKLGFINWDAINKNQVPPPSTRALLYFSRLWEDFKQNTPFLNWKAI----- 411

Query: 1982 SGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSS 2041
                 +S L  R  R+ Q+  Y QH   + +   +     A G        G S   S+S
Sbjct: 412  IEGADASSLQKRAGRADQNYNYNQHAYPTAYGGKYSVKTPAKG--------GVSPSSSAS 463

Query: 2042 HGQHG 2046
              Q G
Sbjct: 464  RVQPG 468



 Score =  100 bits (249), Expect = 2e-20
 Identities = 107/357 (29%), Positives = 146/357 (40%), Gaps = 40/357 (11%)

Query: 2306 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 2365
            GSG       G+  +G+    + G HG G   S G G       ++ G    G+     S
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68

Query: 2366 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 2425
                 G+R    + G R     G++ + G     +  +LG+  H  G     +    RHG
Sbjct: 69   EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124

Query: 2426 SGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST 2485
            + + + S     G    W +S G    GS    GLG      GQ  G   +    G    
Sbjct: 125  ADAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------GQGQG---NPGGLGTPWV 173

Query: 2486 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2545
            HG  G+++G S      GA  GQ  + G    G++      + G GS ++    +  +  
Sbjct: 174  HGYPGNSAG-SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNP 232

Query: 2546 RQSPSYG-RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG-- 2602
              S S G    SG G  S SG  GSG   S+G  ++ SSSG SSS S  G  SG SSG  
Sbjct: 233  PPSGSGGGSSNSGGGSGSQSGSSGSG---SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGS 289

Query: 2603 YGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGH-------GRQGSGSGQS 2652
             G  G   G S      GSS+GSSS  G HG GS   +GH       G +  GSG+S
Sbjct: 290  SGNSGGSRGDSGSESSWGSSTGSSS--GNHG-GSGGGNGHKPGCEKPGNEARGSGES 343



 Score = 99.0 bits (245), Expect = 6e-20
 Identities = 117/484 (24%), Positives = 170/484 (35%), Gaps = 47/484 (9%)

Query: 1106 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ-SPSYGRHGSGSGRSSSSGQHGSGLGES 1164
            G      SG    G+  G++ GHG   + S     + G+   G+  S  S   G G  E+
Sbjct: 19   GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78

Query: 1165 SGFGHHESSS-GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQ-- 1221
             G G  +    G + +       + H+ G   H     Q+    RHG+ +   S  G   
Sbjct: 79   VGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGVPG 137

Query: 1222 HGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHS 1281
            H      S GHG  GS  G       +  GLG    HG  G+ +G S    P  +  G  
Sbjct: 138  HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG-SFGMNPQGAPWGQG 196

Query: 1282 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ-------HGSTSGQSSTFDQEGSSTGQSS 1334
               G    G+    A +Q G GS    +Q +        GS  G S++    GS +G S 
Sbjct: 197  GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG 256

Query: 1335 SYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 1394
            S  +  + +  SSG    G+ SG S      GS      S G  GS S W SS+G     
Sbjct: 257  SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG----- 311

Query: 1395 SGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRS-GQSSRGERHGSSSGSSSSY 1453
                S  G+H  S          G G+GH    E+ G+ + G    G ++  +S    ++
Sbjct: 312  ----SSSGNHGGS----------GGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFNF 357

Query: 1454 GQHGSGSRQSLGH-GQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYES 1512
                   +  LG          Q P PS       S     +        W +       
Sbjct: 358  DTFWKNFKSKLGFINWDAINKNQVPPPSTRALLYFSRLWEDFKQNTPFLNWKAI-----I 412

Query: 1513 GSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH 1572
              + +S L  R  R+ Q+  Y QH   + +   +       G        G S   S+S 
Sbjct: 413  EGADASSLQKRAGRADQNYNYNQHAYPTAYGGKYSVKTPAKG--------GVSPSSSASR 464

Query: 1573 GQHG 1576
             Q G
Sbjct: 465  VQPG 468



 Score = 98.6 bits (244), Expect = 8e-20
 Identities = 103/370 (27%), Positives = 140/370 (37%), Gaps = 53/370 (14%)

Query: 1836 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 1895
            GSG       G+  +G+    + G HG G   S G G       ++ G    G+     S
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68

Query: 1896 SYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1955
                 G+R    + G +     G++ + G     +  +LG+  H  G     +    RHG
Sbjct: 69   EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124

Query: 1956 SGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST 2015
            + + + S  G  G    W +S G    GS    GLG            GQ   + G   T
Sbjct: 125  ADAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------------GQGQGNPGGLGT 170

Query: 2016 HGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2075
               HG     + S G +     Q +  GQ G+G   + G   QG+ +   PG+G   + +
Sbjct: 171  PWVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASN 224

Query: 2076 RQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2135
            +         SGSG  SS+   G G           S SG S S S   + +G SSG   
Sbjct: 225  QNEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSS 273

Query: 2136 HGSRSGQSSRGERHGSSSGSSSRYGQHGSGS-------RQSSGHGRQGSGSGHSP---SR 2185
             GS SG SS G   GSS  S    G  GS S         S  HG  G G+GH P     
Sbjct: 274  SGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP 333

Query: 2186 GRHGSGSGHS 2195
            G    GSG S
Sbjct: 334  GNEARGSGES 343



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 120/485 (24%), Positives = 172/485 (35%), Gaps = 49/485 (10%)

Query: 2046 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ-SPSYGRHGSGSGRSSSSGQHGPGLGES 2104
            G      SG    G+  G++ GHG   + S     + G+   G+  S  S   G G  E+
Sbjct: 19   GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78

Query: 2105 SGFGHHESSS-GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQ-- 2161
             G G  +    G + +       + H+ G   H     Q+    RHG+ +   S  G   
Sbjct: 79   VGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGVPG 137

Query: 2162 HGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHS 2221
            H      S GHG  GS  G       +  G G    HG  G+ +G S    P  +  G  
Sbjct: 138  HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG-SFGMNPQGAPWGQG 196

Query: 2222 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ-------HGSTSGQSSTFDQEGSSTGQSS 2274
               G    G+    A +Q G GS    +Q +        GS  G S++    GS +G S 
Sbjct: 197  GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG 256

Query: 2275 SHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSS-SYGQHGSGSGWSSSSGRHGS 2333
            S G +G  ++ SSS G     S    S G  G  SG+S  S G  GS S W SS+G    
Sbjct: 257  S-GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG---- 311

Query: 2334 GSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRS-GQSSRGERHGSSSGSSSS 2392
                 S  G+H  S          G G+GH    E+ G+ + G    G ++  +S    +
Sbjct: 312  -----SSSGNHGGS----------GGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFN 356

Query: 2393 YGQHGSGSRQSLGH-GQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYE 2451
            +       +  LG          Q P PS       S     +        W +      
Sbjct: 357  FDTFWKNFKSKLGFINWDAINKNQVPPPSTRALLYFSRLWEDFKQNTPFLNWKAI----- 411

Query: 2452 SGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSS 2511
                 +S L  R  R+ Q+  Y QH   + +   +       G        G S   S+S
Sbjct: 412  IEGADASSLQKRAGRADQNYNYNQHAYPTAYGGKYSVKTPAKG--------GVSPSSSAS 463

Query: 2512 HGQHG 2516
              Q G
Sbjct: 464  RVQPG 468



 Score = 95.5 bits (236), Expect = 7e-19
 Identities = 106/376 (28%), Positives = 143/376 (38%), Gaps = 52/376 (13%)

Query: 1366 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSS 1425
            GSG       G+  +G+    + G HG G   S G G       ++ G    G+     S
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68

Query: 1426 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1485
                 G+R    + G R     G++ + G     +  +LG+  H  G     +    RHG
Sbjct: 69   EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124

Query: 1486 SGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSST 1545
            + + + S     G    W +S G    GS    GLG            GQ   + G   T
Sbjct: 125  ADAVRGSWQGVPGHNGAWETSGGHGIFGSQ--GGLG------------GQGQGNPGGLGT 170

Query: 1546 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 1605
               HG     + S G +     Q +  GQ G+G   + G   QG+ +   PG+G   + +
Sbjct: 171  PWVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASN 224

Query: 1606 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 1665
            +         SGSG  SS+   GSG           S SG S S S   + +G SSG   
Sbjct: 225  QNEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSS 273

Query: 1666 HGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHS 1725
             GS SG SS G   GSS  S    G  GS   +SS     GS SG   + G  G G GH 
Sbjct: 274  SGSSSGGSSGGSSGGSSGNSGGSRGDSGS---ESSWGSSTGSSSG---NHGGSGGGNGHK 327

Query: 1726 ---SSHGQHGSGSGRS 1738
                  G    GSG S
Sbjct: 328  PGCEKPGNEARGSGES 343



 Score = 95.1 bits (235), Expect = 9e-19
 Identities = 100/341 (29%), Positives = 146/341 (42%), Gaps = 46/341 (13%)

Query: 2493 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG--YGRQGSGSGQSPGHGQRGSGSRQSPS 2550
            SG+ S+    G + G++  HG  G   S+  G   G++  G+  S      G G+R++  
Sbjct: 26   SGEEST----GTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVG 80

Query: 2551 YG-RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS---------GH- 2599
             G R   G G + + G        + G   HE    Q+    +HG+ +         GH 
Sbjct: 81   TGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIRHGADAVRGSWQGVPGHN 139

Query: 2600 -----SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPS 2654
                 S G+G  GS+ G   +G+ +    G+   +G  G+ S  S G   QG+  GQ  +
Sbjct: 140  GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-SAGSFGMNPQGAPWGQGGN 198

Query: 2655 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGS 2714
             G    G     +  Q G GS R+S++        +        SGSG  S+ S  GSGS
Sbjct: 199  GGPPNFGTNTQGAVAQPGYGSVRASNQ--------NEGCTNPPPSGSGGGSSNSGGGSGS 250

Query: 2715 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSG--YGRHGAGSGQSLSH 2772
                   Q GS+   S+  +  GSS+G SSS    G  S  SSG   G  G   G S S 
Sbjct: 251  -------QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303

Query: 2773 GRHGSGSGQSS-SYGQHGSGSGQSSGYSQHGS---GSGQDG 2809
               GS +G SS ++G  G G+G   G  + G+   GSG+ G
Sbjct: 304  SSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESG 344



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 103/374 (27%), Positives = 141/374 (37%), Gaps = 49/374 (13%)

Query: 897  GSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSS 956
            GSG       G   +G+    + G HG G   S G G   + G+ +G    G+     S 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG--KAIGKEAG----GAAGSKVSE 69

Query: 957  YEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGS 1016
                G+R    +   Q     G++ + G     +  +LG+  H  G     +    RHG+
Sbjct: 70   ALGQGTREAVGTGVRQV-PGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHGA 125

Query: 1017 GSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 1076
             + + S  G       W +S G    GS    GLG            GQ   + G   T 
Sbjct: 126  DAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------------GQGQGNPGGLGTP 171

Query: 1077 GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 1136
              HG     + S G +     Q +  GQ G+G   + G   QG+ +   PG+G   + ++
Sbjct: 172  WVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASNQ 225

Query: 1137 QSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQH 1196
                     SGSG  SS+   GSG           S SG S S S   + +G SSG    
Sbjct: 226  NEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSSS 274

Query: 1197 GSRSGQSSRGERHGSSSGSSSHYGQHGSGS-------RQSSGHGRQGSGSGHSPSRGRHG 1249
            GS SG SS G   GSS  S    G  GS S         S  HG  G G+GH P   + G
Sbjct: 275  GSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG 334

Query: 1250 SGLGHSSSHGQHGS 1263
            +    S   G   S
Sbjct: 335  NEARGSGESGIQNS 348



 Score = 93.6 bits (231), Expect = 3e-18
 Identities = 108/355 (30%), Positives = 144/355 (40%), Gaps = 31/355 (8%)

Query: 484 GSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSP 543
           GSG + G  Q G  S  ++ GE  G   G + S G   +  +++ G     +GS  S + 
Sbjct: 17  GSGEA-GPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGG----AAGSKVSEAL 71

Query: 544 SRGRHES---GSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQES-RSGQSSGYGQ 599
            +G  E+   G RQ   +G       R          +GH  G   ++  R G  +  G 
Sbjct: 72  GQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131

Query: 600 HGSSSGHSS---THGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQ--QGS 654
                GH+    T G HG    Q    GQ     G   +   HG   + +  +G   QG+
Sbjct: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGA 191

Query: 655 GSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYS 714
             GQ  + G          +  Q G GS  +S+     +    S   G  S SG  SG S
Sbjct: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG-S 250

Query: 715 QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGH 774
           Q GS  S S+G   +GS SG        GSSSG SSS G  G  S  SSG+   G   G 
Sbjct: 251 QSGSSGSGSNGDNNNGSSSG--------GSSSG-SSSGGSSGGSSGGSSGN--SGGSRGD 299

Query: 775 SPSRVRHGSSSGHSS-SHGQHGSGTSCSSSC---GHYESGSGQASGFGQHESGSG 825
           S S    GSS+G SS +HG  G G      C   G+   GSG+ SG    E+  G
Sbjct: 300 SGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE-SGIQNSETSPG 353



 Score = 92.4 bits (228), Expect = 6e-18
 Identities = 106/385 (27%), Positives = 148/385 (38%), Gaps = 57/385 (14%)

Query: 1706 GSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 1765
            GSG       G   +G     + G HG G   S   G            G+   G+  S 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66

Query: 1766 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 1825
                 G G+      G        ++  D  G+  G+++    H  G++     G+Q   
Sbjct: 67   VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAA----HALGNT-GHEIGRQAED 119

Query: 1826 ---SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 1882
                G    RG      GH+ ++   G    + S  G  G G G   G G    + W   
Sbjct: 120  VIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVH- 174

Query: 1883 GYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 1942
            GY  + +GS         G+  GQ   G      + +  +  Q G GS ++    +  + 
Sbjct: 175  GYPGNSAGS---FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT- 230

Query: 1943 SGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2002
               +P PS    GSG G S+S G  GS SG         SGSG +      ++ +G SSG
Sbjct: 231  ---NPPPS----GSGGGSSNSGGGSGSQSG--------SSGSGSNG-----DNNNGSSSG 270

Query: 2003 YGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSG 2061
                GSSSG SS     G +SG SS  G  G S G S S    GS +  SSG +G  G G
Sbjct: 271  GSSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGG 323

Query: 2062 SGQSPGHGQRGSGSRQSPSYGRHGS 2086
            +G  PG  + G+ +R S   G   S
Sbjct: 324  NGHKPGCEKPGNEARGSGESGIQNS 348



 Score = 91.7 bits (226), Expect = 1e-17
 Identities = 107/384 (27%), Positives = 149/384 (38%), Gaps = 55/384 (14%)

Query: 1236 GSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 1295
            GSG       G   +G     + G HG G   S   G            G+   G+  S 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66

Query: 1296 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS-SYGHRGSG-SSQSSGYGRHG 1353
                 G G+      G        ++  D  G+  G+++ + G+ G     Q+    RHG
Sbjct: 67   VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAAHALGNTGHEIGRQAEDVIRHG 124

Query: 1354 AGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 1413
            A +     RG      GH+ ++   G    + S  G  G G G   G G    + W    
Sbjct: 125  ADA----VRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVHG- 175

Query: 1414 CTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1473
               +   S  S      G+  GQ   G      + +  +  Q G GS ++    +  +  
Sbjct: 176  ---YPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT-- 230

Query: 1474 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGY 1533
              +P PS    GSG G S+S    G GSG        +SGSS S   G  ++ +G SSG 
Sbjct: 231  --NPPPS----GSGGGSSNS----GGGSG-------SQSGSSGSGSNG--DNNNGSSSGG 271

Query: 1534 GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSGS 1592
               GSSSG SS     G +SG SS  G  G S G S S    GS +  SSG +G  G G+
Sbjct: 272  SSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGN 324

Query: 1593 GQSPGHGQRGSGSRQSPSYGRHGS 1616
            G  PG  + G+ +R S   G   S
Sbjct: 325  GHKPGCEKPGNEARGSGESGIQNS 348



 Score = 91.7 bits (226), Expect = 1e-17
 Identities = 106/379 (27%), Positives = 150/379 (39%), Gaps = 74/379 (19%)

Query: 365 GSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSP 424
           GSG       G+  + +    + G HG     S   G+           G+ + G+  S 
Sbjct: 17  GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGK---------AIGKEAGGAAGSK 66

Query: 425 GHGQRGSGSGQSPSSG-QHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGS 483
                G G+ ++  +G +   GFG + + G  V  + ++ G   HE   + +    +HG+
Sbjct: 67  VSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQ-AEDVIRHGA 125

Query: 484 GS---------GH------SSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSL 528
            +         GH      S GHG  GS+ G   +G+      G+   +G  G+ S  S 
Sbjct: 126 DAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-SAGSF 184

Query: 529 GHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRG-----PYESGSGHSSG 583
           G +  G+  GQ  +   G    G+    +    GYGS R+S++      P  SGSG  S 
Sbjct: 185 GMNPQGAPWGQGGNG--GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS- 241

Query: 584 LGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGS 643
                S SG  SG  Q GSS   S+    +GS+SG SSS    G++SG SS         
Sbjct: 242 -----SNSGGGSG-SQSGSSGSGSNGDNNNGSSSGGSSS----GSSSGGSSG-------- 283

Query: 644 SQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNG-PHGSVSGQSSGFG 702
                 G  G  SG S              S G  GS S W SS G   G+  G   G G
Sbjct: 284 ------GSSGGSSGNS------------GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNG 325

Query: 703 HKSGSGQSSGYSQHGSGSS 721
           HK G  +  G    GSG S
Sbjct: 326 HKPGC-EKPGNEARGSGES 343



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 104/378 (27%), Positives = 142/378 (37%), Gaps = 59/378 (15%)

Query: 782  GSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQ 841
            GS        G+  +GT+   + GH   G G A   G    G   G  + G A+G   S+
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALGH---GLGDALSEGV---GKAIG-KEAGGAAGSKVSE 69

Query: 842  GRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSG 901
                 T     +  +     G + + G     + HA G   H  G               
Sbjct: 70   ALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-------------- 115

Query: 902  QSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHG 961
            Q+    RHG+ + R S  G  G      +  GH    G   G    G G+          
Sbjct: 116  QAEDVIRHGADAVRGSWQGVPGHNGAWETSGGH-GIFGSQGGLGGQGQGN---------- 164

Query: 962  SRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQS 1021
               G       HG    S+ S+G +  G+      GQ G+G      P+ G +  G+   
Sbjct: 165  --PGGLGTPWVHGYPGNSAGSFGMNPQGAPW----GQGGNGG----PPNFGTNTQGAVAQ 214

Query: 1022 SSYGPYRSGSGWSSSRGPYESGSGHSS-----GLGHRESRSGQ-SSGYGQHGSSSGHSST 1075
              YG  R+ +       P  SGSG  S     G G +   SG  S+G   +GSSSG SS+
Sbjct: 215  PGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSS 274

Query: 1076 HGQHGSTSGQSS------SCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSGSGQSPGH 1128
                GS+SG SS      S G  G S G S S    GS +  SSG +G  G G+G  PG 
Sbjct: 275  ----GSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGC 330

Query: 1129 GQRGSGSRQSPSYGRHGS 1146
             + G+ +R S   G   S
Sbjct: 331  EKPGNEARGSGESGIQNS 348



 Score = 90.9 bits (224), Expect = 2e-17
 Identities = 105/385 (27%), Positives = 148/385 (38%), Gaps = 57/385 (14%)

Query: 2176 GSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 2235
            GSG       G   +G+    + G HG G   S   G            G+   G+  S 
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66

Query: 2236 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 2295
                 G G+      G        ++  D  G+  G+++    H  G++     G+Q   
Sbjct: 67   VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAA----HALGNT-GHEIGRQAED 119

Query: 2296 ---SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 2352
                G    RG      GH+ ++   G    + S  G  G G G   G G    + W   
Sbjct: 120  VIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVH- 174

Query: 2353 GYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 2412
            GY  + +GS         G+  GQ   G      + +  +  Q G GS ++    +  + 
Sbjct: 175  GYPGNSAGS---FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT- 230

Query: 2413 SGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2472
               +P PS    GSG G S+S    G GSG         S SG S    + ++ +G SSG
Sbjct: 231  ---NPPPS----GSGGGSSNS----GGGSG---------SQSGSSGSGSNGDNNNGSSSG 270

Query: 2473 YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSG 2531
                GSSSG SS     G +SG SS  G  G S G S S    GS +  SSG +G  G G
Sbjct: 271  GSSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGG 323

Query: 2532 SGQSPGHGQRGSGSRQSPSYGRHGS 2556
            +G  PG  + G+ +R S   G   S
Sbjct: 324  NGHKPGCEKPGNEARGSGESGIQNS 348



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 106/377 (28%), Positives = 155/377 (41%), Gaps = 58/377 (15%)

Query: 196 GSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSS 255
           GSG       G+  +G+    +   HG G   S G  +   + G+ +G +   +GS  S 
Sbjct: 17  GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGK---AIGKEAGGA---AGSKVSE 69

Query: 256 GYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSG 315
             GQ G+R    + G R     G++ + G     +  +LG+     G RQ+   +RHG+ 
Sbjct: 70  ALGQ-GTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIG-RQAEDVIRHGAD 126

Query: 316 SGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQG 375
           +   S  G  G   ++  S GH   GS         + G G        G G G+    G
Sbjct: 127 AVRGSWQGVPGHNGAWETSGGHGIFGS---------QGGLG--------GQGQGNPGGLG 169

Query: 376 Q---HGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQ---- 428
               HG     A S G +     Q + +GQ  +    + G   ++ G+   PG+G     
Sbjct: 170 TPWVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGT--NTQGAVAQPGYGSVRAS 223

Query: 429 -RGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGH 487
            +  G    P SG  G   G S+S G   S SG S    + ++++  SSG +  GS SG 
Sbjct: 224 NQNEGCTNPPPSGSGG---GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG 280

Query: 488 SSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLG-HSRHGSGSGQSP----- 541
           SSG G  G  SG S      G S G S S    GS +  S G H   G G+G  P     
Sbjct: 281 SSG-GSSGGSSGNS------GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP 333

Query: 542 -SPSRGRHESGSRQSSS 557
            + +RG  ESG + S +
Sbjct: 334 GNEARGSGESGIQNSET 350



 Score = 90.1 bits (222), Expect = 3e-17
 Identities = 106/375 (28%), Positives = 141/375 (37%), Gaps = 61/375 (16%)

Query: 682  SGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQ 741
            SG  S+    G   G   G     G G++ G    G+  S  S     G+R    +   Q
Sbjct: 26   SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85

Query: 742  ---HGSSSGLSSSYGQ--HGSGSHQSSGH--GRQGSGSGHSPSRVRHGSSSGHSSSHGQH 794
                G++  L +  G+  H  G+   +GH  GRQ          +RHG+ +   S  G  
Sbjct: 86   VPGFGAADALGNRVGEAAHALGN---TGHEIGRQAEDV------IRHGADAVRGSWQGVP 136

Query: 795  GSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSS 854
            G   +  +S GH   GS    G      G GQG        G   +   HG     + S 
Sbjct: 137  GHNGAWETSGGHGIFGSQGGLG------GQGQGNP------GGLGTPWVHGYPGNSAGSF 184

Query: 855  GQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSG 914
            G +     Q + +GQ                G+G  P  G    G+   P YG   + + 
Sbjct: 185  GMNP----QGAPWGQ---------------GGNGGPPNFGTNTQGAVAQPGYGSVRASNQ 225

Query: 915  RSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHG 974
                +    SGSG     G  S+SG  SG     SGSG +       S  G SS S   G
Sbjct: 226  NEGCTNPPPSGSG-----GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG 280

Query: 975  SSSGSSSSYGQHGSGSRQSLGHGQHGSGS--GQSPSPSRGRHGSGSGQSSSYGPYRSGSG 1032
            SS GSS     +  GSR     G  GS S  G S   S G HG GSG  + + P     G
Sbjct: 281  SSGGSSGGSSGNSGGSR-----GDSGSESSWGSSTGSSSGNHG-GSGGGNGHKPGCEKPG 334

Query: 1033 WSSSRGPYESGSGHS 1047
             + +RG  ESG  +S
Sbjct: 335  -NEARGSGESGIQNS 348



 Score = 88.6 bits (218), Expect = 8e-17
 Identities = 93/314 (29%), Positives = 123/314 (39%), Gaps = 14/314 (4%)

Query: 2516 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ-SPSYGRHGSGSGRSSSSGQHGSGLGES 2574
            G      SG    G+  G++ GHG   + S     + G+   G+  S  S   G G  E+
Sbjct: 19   GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78

Query: 2575 SGFGHHESSS-GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQ-- 2631
             G G  +    G + +       + H+ G   H     Q+    RHG+ +   S  G   
Sbjct: 79   VGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGVPG 137

Query: 2632 HGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHS 2691
            H      S GHG  GS  G       +  GLG    HG  G+ +G S    P  +  G  
Sbjct: 138  HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG-SFGMNPQGAPWGQG 196

Query: 2692 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGS 2751
               G    G+    A +Q G GS    +Q + G T+   S     GS  G S+S G  GS
Sbjct: 197  GNGGPPNFGTNTQGAVAQPGYGSVRASNQNE-GCTNPPPS-----GSGGGSSNSGGGSGS 250

Query: 2752 GSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYS 2811
             S  SSG G +G  +  S S G     S   SS G  G  SG S G S+  SGS     S
Sbjct: 251  QSG-SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG-SRGDSGSESSWGS 308

Query: 2812 YCKGGSNHDGGSSG 2825
                 S + GGS G
Sbjct: 309  STGSSSGNHGGSGG 322



 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 91/346 (26%), Positives = 134/346 (38%), Gaps = 35/346 (10%)

Query: 878  SGRGRHGSGSGQSPGHGQRGSGS-GQSPSYGRHGSGSGRSSSSGRHGSGSGQS------- 929
            SG    G+  G++ GHG   + S G   + G+   G+  S  S   G G+ ++       
Sbjct: 26   SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85

Query: 930  -SGFGHKSSSGQSSGYTQHGSGS-GHSSSYE-----QHGSRSGQSSRSEQHGSSSGSSSS 982
              GFG   + G   G   H  G+ GH    +     +HG+ + + S     G +    +S
Sbjct: 86   VPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETS 145

Query: 983  YGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYES 1042
             G    GS+  LG    G+  G       G  G+ +G   S+G    G+ W       + 
Sbjct: 146  GGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG---SFGMNPQGAPWG------QG 196

Query: 1043 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH 1102
            G+G     G     +    GYG   +S+ +       G T+   S  G   ++SG  S  
Sbjct: 197  GNGGPPNFGTNTQGAVAQPGYGSVRASNQNE------GCTNPPPSGSGGGSSNSGGGSG- 249

Query: 1103 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRG--SGSRQSPSYGRHGSGSGRSSSSGQHGSG 1160
             Q GS  S S+G    GS SG S      G  SG     S G  G   G S S    GS 
Sbjct: 250  SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSS 309

Query: 1161 LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 1206
             G SS  G+H  S G +            + G G+ G ++ ++S G
Sbjct: 310  TGSSS--GNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353



 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 99/362 (27%), Positives = 140/362 (38%), Gaps = 37/362 (10%)

Query: 1340 GSGSSQSSGYGRHGAGSGQSPSRGRHGSGS----GHSSSYGQHGSGSGWSSSSGRHGSGS 1395
            GSG +     G    G+    + G HG G     G   + G+   G+  S  S   G G+
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75

Query: 1396 GQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSS--GSSSSY 1453
             ++ G G  +   + ++    +  G    +          Q+    RHG+ +  GS    
Sbjct: 76   REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135

Query: 1454 GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESG 1513
              H      S GHG  GS  G          G G G     +P G G+ W      Y   
Sbjct: 136  PGHNGAWETSGGHGIFGSQGGLG--------GQGQG-----NPGGLGTPWVHG---YPGN 179

Query: 1514 SSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHG 1573
            S+ S G+  + +  GQ    G     +       Q G  S ++S+  + G ++   S  G
Sbjct: 180  SAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE-GCTNPPPSGSG 238

Query: 1574 QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGE 1633
              G  S+   G G Q SGS  S  +G   +GS         GS SG SSS G  G   G 
Sbjct: 239  --GGSSNSGGGSGSQ-SGSSGSGSNGDNNNGSSSG------GSSSG-SSSGGSSGGSSGG 288

Query: 1634 SSGFGHHESSSGQSSSYSQHGSGSGHSSG-YGQHGSRSGQSSRGERHGSSSRSSSRYGQH 1692
            SS  G+   S G S S S  GS +G SSG +G  G  +G     E+ G+ +R S   G  
Sbjct: 289  SS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ 346

Query: 1693 GS 1694
             S
Sbjct: 347  NS 348



 Score = 83.6 bits (205), Expect = 3e-15
 Identities = 98/362 (27%), Positives = 141/362 (38%), Gaps = 37/362 (10%)

Query: 2280 GSGSSQSSSYGQQGSGSGQSPSRGRHGSGS----GHSSSYGQHGSGSGWSSSSGRHGSGS 2335
            GSG +     G++ +G+    + G HG G     G   + G+   G+  S  S   G G+
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75

Query: 2336 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSS--GSSSSY 2393
             ++ G G  +   + ++    +  G    +          Q+    RHG+ +  GS    
Sbjct: 76   REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135

Query: 2394 GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESG 2453
              H      S GHG  GS  G          G G G     +P G G+ W      Y   
Sbjct: 136  PGHNGAWETSGGHGIFGSQGGLG--------GQGQG-----NPGGLGTPWVHG---YPGN 179

Query: 2454 SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHG 2513
            S  S G+  + +  GQ    G     +       Q G  S ++S+  + G ++   S  G
Sbjct: 180  SAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE-GCTNPPPSGSG 238

Query: 2514 QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGE 2573
              G  S+   G G Q SGS  S  +G   +GS         GS SG SSS G  G   G 
Sbjct: 239  --GGSSNSGGGSGSQ-SGSSGSGSNGDNNNGSSSG------GSSSG-SSSGGSSGGSSGG 288

Query: 2574 SSGFGHHESSSGQSSSYSQHGSGSGHSSG-YGQHGSRSGQSSRGERHGSSSGSSSHYGQH 2632
            SS  G+   S G S S S  GS +G SSG +G  G  +G     E+ G+ +  S   G  
Sbjct: 289  SS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ 346

Query: 2633 GS 2634
             S
Sbjct: 347  NS 348



 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 75/280 (26%), Positives = 112/280 (40%), Gaps = 29/280 (10%)

Query: 180 GEQNSDSHQSSGRGQCGSGSGQSPNYGQH---GSGSGQSS---SNDTHGSGSGQSSGFSQ 233
           G + S++     R   G+G  Q P +G     G+  G+++    N  H  G  Q+    +
Sbjct: 64  GSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIR 122

Query: 234 HKSSS--GQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGS------------ 279
           H + +  G   G   H      S G+G  GS+ G   +G+ +    G+            
Sbjct: 123 HGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG 182

Query: 280 -------SSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYS 332
                   + +GQ G+G   + G   QG+ ++     VR  + +   ++    GSG   S
Sbjct: 183 SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242

Query: 333 YSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGS 392
            S G   S SG +      ++ +G SSG S  GS SG SS     GS+     S G  GS
Sbjct: 243 NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGS 302

Query: 393 SSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSG 432
            S   SS G        S G   H  G  + PG+  RGSG
Sbjct: 303 ESSWGSSTGSSSGNHGGSGGGNGHKPGC-EKPGNEARGSG 341



 Score = 82.4 bits (202), Expect = 6e-15
 Identities = 94/360 (26%), Positives = 139/360 (38%), Gaps = 41/360 (11%)

Query: 1810 GSGSSQSSSYGQQGSGSGQSPSRGRHGSGS----GHSSSYGQHGSGSGWSSSSGRHGSGS 1865
            GSG +     G++ +G+    + G HG G     G   + G+   G+  S  S   G G+
Sbjct: 17   GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75

Query: 1866 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSS--GSSSSY 1923
             ++ G G  +   + ++    +  G    +          Q+    +HG+ +  GS    
Sbjct: 76   REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135

Query: 1924 GQHGSGSRQSLGHGQHGS-----GSGQSPSPSRGR---HGSGSGQSSSYGPYGSGSGWSS 1975
              H      S GHG  GS     G GQ      G    HG     + S+G    G+ W  
Sbjct: 136  PGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWG- 194

Query: 1976 SRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGAS 2035
                 + G+G     G     +    GYG   +S+ +        S SG  SS    G+ 
Sbjct: 195  -----QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249

Query: 2036 SGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSG 2095
            S       Q GS  S S+G    GS SG S       SGS    S G  GS  G S +SG
Sbjct: 250  S-------QSGSSGSGSNGDNNNGSSSGGS------SSGSSSGGSSG--GSSGGSSGNSG 294

Query: 2096 QHGPGLGESSGFGHHESSSGQSS-SYSQHGSGSGHSSGYGQHGSRS-GQSSRGERHGSSS 2153
                  G  S +G   SS+G SS ++   G G+GH  G  + G+ + G    G ++  +S
Sbjct: 295  GSRGDSGSESSWG---SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETS 351



 Score = 82.4 bits (202), Expect = 6e-15
 Identities = 100/384 (26%), Positives = 142/384 (36%), Gaps = 62/384 (16%)

Query: 490 GHGQHGS-RSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRH-----GSGSGQSPSP 543
           G G+ G  +SG+ S G   G + G       HG G   S G  +      G  +G   S 
Sbjct: 17  GSGEAGPLQSGEESTGTNIGEALG-------HGLGDALSEGVGKAIGKEAGGAAGSKVSE 69

Query: 544 SRGRHESGSRQSSSYGPHGY-GSGRSSSRGPYESGSGHSSG-LGHQESRSGQSSGYGQHG 601
           + G+   G+R++   G     G G + + G     + H+ G  GH+  R  Q+    +HG
Sbjct: 70  ALGQ---GTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR--QAEDVIRHG 124

Query: 602 SSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPS 661
           + +   S  G  G      +S              G HG   SQ    GQ     G   +
Sbjct: 125 ADAVRGSWQGVPGHNGAWETS--------------GGHGIFGSQGGLGGQGQGNPGGLGT 170

Query: 662 RGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKS-GSGQSSGYSQHGSGS 720
              HG     + S+G +  G+ W           GQ    G  + G+      +Q G GS
Sbjct: 171 PWVHGYPGNSAGSFGMNPQGAPW-----------GQGGNGGPPNFGTNTQGAVAQPGYGS 219

Query: 721 SHSSGYRKHGSR---SGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPS 777
             +S   +  +    SG    S   G  SG  S  G  GSGS+   G    GS SG    
Sbjct: 220 VRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQS--GSSGSGSN---GDNNNGSSSG---- 270

Query: 778 RVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGH 837
               GSSSG SS     GS    S + G     SG  S +G     S   +   G  +GH
Sbjct: 271 ----GSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGH 326

Query: 838 FSSQGRHGSTSGQSSSSGQHDSSS 861
                + G+ +  S  SG  +S +
Sbjct: 327 KPGCEKPGNEARGSGESGIQNSET 350



 Score = 80.9 bits (198), Expect = 2e-14
 Identities = 96/352 (27%), Positives = 136/352 (38%), Gaps = 45/352 (12%)

Query: 640 GSGSSQSSRYGQQGSGSGQSPSRGRHGSDF---GHSSSYGQHGSGSGWSSSNGPHGSVSG 696
           GSG +   + G++ +G+    + G    D    G   + G+   G+  S  +   G  + 
Sbjct: 17  GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76

Query: 697 QS--------SGFGHKSGSGQSSGYSQHGSGSS-HSSGYR-----KHGSRSGQSSRSEQH 742
           ++         GFG     G   G + H  G++ H  G +     +HG+ + + S     
Sbjct: 77  EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVP 136

Query: 743 GSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSS 802
           G +    +S G    GS    G   QG+  G     V HG     + S G +  G     
Sbjct: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWV-HGYPGNSAGSFGMNPQGAPWG- 194

Query: 803 SCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGR-------HGSTSGQSSSSG 855
                + G+G    FG +  G+    +Q G  S   S+Q          GS  G S+S G
Sbjct: 195 -----QGGNGGPPNFGTNTQGA---VAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246

Query: 856 QHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGS---- 911
              S SG S S    ++ +  +SG    GS SG S G    GS      S G  GS    
Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306

Query: 912 GSGRSSSSGRH-GSGSGQSSGFGHKSSSGQSSGYTQHGSG-SGHSSSYEQHG 961
           GS   SSSG H GSG G     GHK    +  G    GSG SG  +S    G
Sbjct: 307 GSSTGSSSGNHGGSGGGN----GHKPGC-EKPGNEARGSGESGIQNSETSPG 353



 Score = 74.7 bits (182), Expect = 1e-12
 Identities = 57/170 (33%), Positives = 74/170 (43%), Gaps = 16/170 (9%)

Query: 174 GQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQ-------HGSGSGQSSSNDTHGSGSG 226
           GQ  + G  N  ++      Q G GS ++ N  +        GSG G S+S    GS SG
Sbjct: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253

Query: 227 QSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQH 286
            S   S   +++G SSG S  GS SG SSG    GS  G S      R  SGS SS+G  
Sbjct: 254 SSGSGSNGDNNNGSSSGGSSSGSSSGGSSG----GSSGGSSGNSGGSRGDSGSESSWG-- 307

Query: 287 GSGSRQSLGHGRQGSGSRQSPSHVRHGS---GSGHSSSHGQHGSGSSYSY 333
            S    S  HG  G G+   P   + G+   GSG S       S   +++
Sbjct: 308 SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFNF 357



 Score = 73.2 bits (178), Expect = 4e-12
 Identities = 90/333 (27%), Positives = 130/333 (39%), Gaps = 55/333 (16%)

Query: 206 GQHGSGSGQSSSNDTHGSGSGQSSGFSQHK-------SSSGQSSGYSQHGSGS-GHSSGY 257
           G+   G+  S  ++  G G+ ++ G    +        + G   G + H  G+ GH  G 
Sbjct: 56  GKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR 115

Query: 258 G-----QHGSRSGQSSRGERHRSSSGSSSSYGQHGS-GSRQSLGHGRQGSGSRQSPSHVR 311
                 +HG+ + + S  +     +G+  + G HG  GS+  LG   QG+        V 
Sbjct: 116 QAEDVIRHGADAVRGS-WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWV- 173

Query: 312 HGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGY-----SKHGS 366
           HG     + S G +  G+ +       + G+G    FG +  G+    GY     S    
Sbjct: 174 HGYPGNSAGSFGMNPQGAPWG------QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE 227

Query: 367 GSGHSSSQGQHGSTSGQASSSG-QHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPG 425
           G  +    G  G +S     SG Q GSS   S S G + + S  SSG     S SG S G
Sbjct: 228 GCTNPPPSGSGGGSSNSGGGSGSQSGSSG--SGSNGDNNNGS--SSG----GSSSGSSSG 279

Query: 426 HGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGS 485
               GS  G   SSG  G   G S S   + S +G SSG                HG GS
Sbjct: 280 GSSGGSSGG---SSGNSGGSRGDSGSESSWGSSTGSSSG---------------NHG-GS 320

Query: 486 GHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYG 518
           G  +GH     + G  +RG  +     S +S G
Sbjct: 321 GGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353



 Score = 67.0 bits (162), Expect = 3e-10
 Identities = 87/331 (26%), Positives = 128/331 (38%), Gaps = 58/331 (17%)

Query: 81  LVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEE-----------NKRQESSFSH 129
           L +   K IGK+    +GSK+ +   Q   E   T   +           N+  E++  H
Sbjct: 47  LSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAA--H 104

Query: 130 SSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSY--SGQSSSYGEQNSDSH 187
           +  + G      R     ++ G +++  R S+Q    G + ++  SG    +G Q     
Sbjct: 105 ALGNTGHE--IGRQAEDVIRHGADAV--RGSWQ-GVPGHNGAWETSGGHGIFGSQGGLGG 159

Query: 188 QSSGR----------GQCGSGSG------QSPNYGQHGSGSGQSSSNDTHGSGSGQSSGF 231
           Q  G           G  G+ +G      Q   +GQ G+G   +   +T G+ +    G 
Sbjct: 160 QGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGS 219

Query: 232 SQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSR 291
            +  + +   +     GSG G S+  G  GS+SG S  G    +++GSSS     GS S 
Sbjct: 220 VRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSG 279

Query: 292 QSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQH 351
            S G G  G            GS      S G  GS SS+  S G   S SG   G G  
Sbjct: 280 GSSG-GSSG------------GSSGNSGGSRGDSGSESSWGSSTG---SSSGNHGGSG-- 321

Query: 352 ESGSGQSSGYSKHGS---GSGHSSSQGQHGS 379
             G+G   G  K G+   GSG S  Q    S
Sbjct: 322 -GGNGHKPGCEKPGNEARGSGESGIQNSETS 351



 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 53/166 (31%), Positives = 66/166 (39%), Gaps = 13/166 (7%)

Query: 132 WSAGEND---SYSRNVRGSL-KPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSH 187
           W  G N    ++  N +G++ +PG  S+  R S Q +  G  N     S   G  NS   
Sbjct: 193 WGQGGNGGPPNFGTNTQGAVAQPGYGSV--RASNQNE--GCTNPPPSGSGG-GSSNSGGG 247

Query: 188 QSSGRGQCGSGSGQSPNYGQH--GSGSGQSSSNDTHGSGSGQS--SGFSQHKSSSGQSSG 243
             S  G  GSGS    N G    GS SG SS   + GS  G S  SG S+  S S  S G
Sbjct: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG 307

Query: 244 YSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSG 289
            S   S   H    G +G + G    G   R S  S     +   G
Sbjct: 308 SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo
            sapiens]
          Length = 2191

 Score =  102 bits (255), Expect = 4e-21
 Identities = 222/974 (22%), Positives = 327/974 (33%), Gaps = 121/974 (12%)

Query: 233  QHKSSSGQSSGYSQHGSGS-GHSSGYGQHGSRSGQSSRGE----------RHRSSSGSSS 281
            QH  S+  S G +  G+   G      QHG     ++ G+          +      +  
Sbjct: 73   QHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPP 132

Query: 282  SYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESG 341
              G+   G  +  G G    G++Q P  V  G G   +     +  GS+   S G    G
Sbjct: 133  KMGEPAGGRYEHPGLG--ALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGG---PG 187

Query: 342  SGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSR-QSSSY 400
                  F QH        G    G G  HS+S          A+++G  GS    Q+S  
Sbjct: 188  GRAGPCFDQH-------GGQQSPGMGMMHSAS----------AAAAGAPGSMDPLQNSHE 230

Query: 401  GQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTG------FGRSSSSGP 454
            G   S   H  G  +  +G G   G G  G GSG     G  G G         ++++  
Sbjct: 231  GYPNSQCNHYPGYSRPGAGGGGGGGGGG-GGGSGGGGGGGGAGAGGAGAGAVAAAAAAAA 289

Query: 455  YVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSS 514
              +G G   G+G   +     S   Q G G     G G   S S  ++     GS+AG  
Sbjct: 290  AAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAA-----GSAAGGF 344

Query: 515  SSY---GQHGSGSRQSLGHSRHGSGSGQSPSPSR----GRHESGSRQSSSYGPHGYGSGR 567
              +    QH SG+  +L           SPSP      G +   S  S+   P      +
Sbjct: 345  QRFAGQNQHPSGATPTLNQLL------TSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398

Query: 568  SSSRGPYESGSGHSSGLGHQESRSGQ----SSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 623
            +++ G    G   ++G+G  +    Q    S  +      S  + + G  G T G+S   
Sbjct: 399  AAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGS 458

Query: 624  GQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRH---------GSDFGHSSS 674
                    +   +G   +  SQ  +      GS   P   R+         G+  G    
Sbjct: 459  PMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYP 518

Query: 675  YGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSG 734
              Q    + W  +        GQ    G+    GQ   YSQ           +   S+S 
Sbjct: 519  QQQDSGDATWKETFWLMPPQYGQQGVSGY-CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQ 577

Query: 735  QSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQH 794
            Q  + +Q  S  G       +G+ S      G+      +   + R  S    S S    
Sbjct: 578  QRYQPQQDMSQEG-------YGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL 630

Query: 795  GSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSS 854
             +GT  + S     S SG  S  G   + +   +S H  AS H SS     S S   S  
Sbjct: 631  PTGTEATLSSA--VSASGSTSSQGDQSNPAQSPFSPH--ASPHLSSIPGGPSPSPVGSPV 686

Query: 855  GQHDSSSGQSSSY-------------GQHESASHHASGRGRHGSGSGQSPGHGQRG--SG 899
            G + S SG  S                Q ES+SH A           QSP   +RG  +G
Sbjct: 687  GSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPA---------LSQSPMPQERGFMAG 737

Query: 900  SGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQ 959
            + ++P   ++G      S S     G    +G      S  S  Y    S  G   +Y +
Sbjct: 738  TQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSR 797

Query: 960  HGSRSGQSSRS-EQHGSSSGSSSSYGQHGSGSRQSLGHGQHG----SGSGQSPSPSR--G 1012
              + SG  S S    G   G S++   HG G  Q  G    G    +G    P P     
Sbjct: 798  PPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSS 857

Query: 1013 RHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSG-HSSGLGHRESRSGQSSGYGQHG--SS 1069
               S  G S   GP       + +R   E+ +    +     +SR G   G  Q G  +S
Sbjct: 858  MTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMAS 917

Query: 1070 SGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG---SGSGQSP 1126
            S   S    + S+   + +     A +  +SS    G     S G  +        G+  
Sbjct: 918  SSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEE 977

Query: 1127 GHGQRGSGSRQSPS 1140
            G  Q  S S++S S
Sbjct: 978  GTPQPESKSKKSSS 991



 Score =  102 bits (254), Expect = 5e-21
 Identities = 303/1398 (21%), Positives = 477/1398 (34%), Gaps = 185/1398 (13%)

Query: 468  HESSSEHSSGYTQHGSGS-GHSSGHGQHGSRSGQSSRGE----------RQGSSAGSSSS 516
            H  S+ +S G    G+   G      QHG     ++ G+          + G    +   
Sbjct: 74   HPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPK 133

Query: 517  YGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES 576
             G+   G  +  G    G+       P  G   +   + ++Y    YGS   +S GP   
Sbjct: 134  MGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNY----YGSAAPASGGP--- 186

Query: 577  GSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSH 636
              G  +G    +    QS G G   S+S               +++ G  G+     +SH
Sbjct: 187  --GGRAGPCFDQHGGQQSPGMGMMHSAS---------------AAAAGAPGSMDPLQNSH 229

Query: 637  -GQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVS 695
             G   S  +    Y + G+G G     G  G   G  S  G  G G+G   +    G+V+
Sbjct: 230  EGYPNSQCNHYPGYSRPGAGGG-----GGGGGGGGGGSGGGGGGGGAGAGGAGA--GAVA 282

Query: 696  GQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQH 755
              ++     +G G   GY    +G    S  R+ G   G        G++S   ++ G  
Sbjct: 283  AAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQG--GGMMMGPGGGGAASLSKAAAGSA 340

Query: 756  GSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCS------SSCGHYES 809
              G  + +G  +  SG+  + +++    S    S  G +   +S S      S      +
Sbjct: 341  AGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAA 400

Query: 810  GSGQASGFGQHESGSGQGY---SQHGSASGHFS----------SQGRHGSTSGQSSSSGQ 856
             +G A+G  Q  +G G G    +Q+ +AS  ++          S G  G T G+S  S  
Sbjct: 401  AAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPM 460

Query: 857  HDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSG-SGQSPSYGRHGSGSGR 915
                  +   YG   +          +  GS   PG  +   G  G++P     G+ +G 
Sbjct: 461  DPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTP-----GAMAGM 515

Query: 916  SSSSGR-HGSGSGQSSGFGHKSSSGQS--SGYTQHGSGSGHSSSYE-QHGSRSGQ--SSR 969
                 +  G  + + + +      GQ   SGY Q G    +S   +  H     Q   S+
Sbjct: 516  QYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQ 575

Query: 970  SEQHGSSSGSSSSYGQHGSGSRQSLGHGQ---HGSGSGQSPSPSRGRHGSGS------GQ 1020
            S+Q        S  G +G+ S+  L  G+         Q   PS     SGS      G 
Sbjct: 576  SQQRYQPQQDMSQEG-YGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGT 634

Query: 1021 SSSYGPYRSGSGWSSSRG----PYES-----GSGHSSGLGHRESRSGQSSGYGQHGSSSG 1071
             ++     S SG +SS+G    P +S      S H S +    S S   S  G + S SG
Sbjct: 635  EATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSG 694

Query: 1072 HSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG--SGSGQSPGHG 1129
              S     GS         Q   S  +SSSH       SQS     +G  +G+ ++P   
Sbjct: 695  PISPASIPGSQMPP-----QPPGSQSESSSH----PALSQSPMPQERGFMAGTQRNPQMA 745

Query: 1130 QRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSG- 1188
            Q G   +  PS   H S  G+  +          S  +G   S  G   +YS+  + SG 
Sbjct: 746  QYGP-QQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGV 804

Query: 1189 HSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSG------HGRQGSGSGHS 1242
             S+ Y   G   G S+  + HG   G S   G    G   S+G       G   S +  S
Sbjct: 805  PSASYSGPGPGMGISANNQMHG--QGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSS 862

Query: 1243 PSRGRHGS-GLGHS----SSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG-SGHSSA 1296
            P   + G  G+G      +   Q  + +   ++    +SR G  S  G ++SG    SS 
Sbjct: 863  PGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQG--SFPGMNQSGLMASSSP 920

Query: 1297 YSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGS 1356
            YSQ  + S    +  Q    S   +  +   +S G +       S             G+
Sbjct: 921  YSQPMNNSSSLMNT-QAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGT 979

Query: 1357 GQSPSRGRHGSGSGHSS-------SYGQHGSGSGW----SSSSGRHGSGSGQSSGFGHHE 1405
             Q  S+ +  S S  +          G       W     +     GS        G   
Sbjct: 980  PQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKP 1039

Query: 1406 SSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLG 1465
               ++   C +   G    +  ++    +   + G    ++S     Y Q+       + 
Sbjct: 1040 LDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIE 1099

Query: 1466 HGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGL----G 1521
                    G+ P P     G    Q     P  + SG  S +GP    S+ S+ +    G
Sbjct: 1100 R-------GEEPPPEVFSTGDTKKQPKLQPPSPANSG--SLQGPQTPQSTGSNSMAEVPG 1150

Query: 1522 HRESRSGQSSGYGQ-HGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS 1580
              +  +  S+ +GQ      G SST   H   S  S S      S   ++ + Q   G S
Sbjct: 1151 DLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQ---GMS 1207

Query: 1581 QSSGYGRQGSGSGQSPGHGQRGSGSRQSP--SYGRHGSGS-----GRSSSSGQHGSGLGE 1633
                 GR      + P  G R       P  + G+  + S      +S S      G+G+
Sbjct: 1208 MPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQ 1267

Query: 1634 SSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS----GQSSRGERH-------GSS 1682
               F +  S   +   Y Q   G G  SG   +G        Q    +RH        + 
Sbjct: 1268 RQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAK 1327

Query: 1683 SRSSSRYGQHGSGSRQS--SGHGRQGSGSGQSPSRGRHG--------SGLGHSSSHG--- 1729
                  Y    S  +Q   + +G   SG  + P +G++          G G   +HG   
Sbjct: 1328 RHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPP 1387

Query: 1730 -QHGSGSGRSSSRGPYES 1746
               G     SSS GP ++
Sbjct: 1388 QMMGGPLQSSSSEGPQQN 1405



 Score = 94.7 bits (234), Expect = 1e-18
 Identities = 180/807 (22%), Positives = 280/807 (34%), Gaps = 85/807 (10%)

Query: 1392 GSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSS 1451
            G G      F ++  S+  +SG    G G      ++QHG +      G  H +S+ ++ 
Sbjct: 163  GGGPAAVPEFNNYYGSAAPASG----GPGGRAGPCFDQHGGQQSPGM-GMMHSASAAAAG 217

Query: 1452 SYGQHG--SGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGP 1509
            + G       S +   + Q     G S  P  G  G G G     S  G G G + + G 
Sbjct: 218  APGSMDPLQNSHEGYPNSQCNHYPGYS-RPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGA 276

Query: 1510 YESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQS 1569
                 + ++      +  G   GYG  GSS+G+           G     G  GA+S   
Sbjct: 277  GAGAVAAAAAAAAAAAGGGGGGGYG--GSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSK 334

Query: 1570 SSHGQHGSGSSQSSGYGRQGSGSG-------QSPGHGQRGSGSR-----------QSPSY 1611
            ++ G    G  + +G  +  SG+         SP    R  G               PS 
Sbjct: 335  AAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQ 394

Query: 1612 GRHGSGSGRSSSSGQH---GSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS 1668
             +  + +  +++ GQ    G GLG+  G  +  +S   +++  +    S  +   G  G 
Sbjct: 395  PQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQR----SHPAMSPGTPGP 450

Query: 1669 RSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSH 1728
              G+S          +    YG   +   Q         GS   P   R+  G+      
Sbjct: 451  TMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGI------ 504

Query: 1729 GQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG 1788
             Q  +    +  + P +  SG ++     E+       Y Q G     +C QGQ    S 
Sbjct: 505  -QGRTPGAMAGMQYPQQQDSGDAT---WKETFWLMPPQYGQQGVSG--YCQQGQQPYYSQ 558

Query: 1789 QSS------------TFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHG 1836
            Q              +  Q+     Q  S   +G+ S    + G+          + R  
Sbjct: 559  QPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPS 618

Query: 1837 SGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSS 1896
            S    S S     +G+  + SS    SGS  S G    + S+   S ++ H   S H SS
Sbjct: 619  SLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQG----DQSNPAQSPFSPH--ASPHLSS 672

Query: 1897 YEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS----GQSPSPSRG 1952
                 S S   S    + S SG  S     GS         Q  S S     QSP P   
Sbjct: 673  IPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQER 732

Query: 1953 RHGSGSGQSSSYGPYG-SGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG 2011
               +G+ ++     YG   +G S S  P   G  H+     ++S S  S  YG   S  G
Sbjct: 733  GFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNS--SGTYGPQMSQYG 790

Query: 2012 HSSTHGQHGSASG-QSSSCGQHGASSGQSSSHGQHGSGSSQSSG---YGRQGSGSGQS-P 2066
                + +  + SG  S+S    G   G S+++  HG G SQ  G    GR  S   Q+ P
Sbjct: 791  PQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRP 850

Query: 2067 GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSG 2126
              G   S +  SP   + G G G        GP +   +      +++   ++ +   S 
Sbjct: 851  FPGNMSSMTPSSPGMSQQG-GPGM-------GPPMPTVNRKAQEAAAAVMQAAANSAQSR 902

Query: 2127 SGHSSGYGQHGSRSGQSSRGERHGSSS 2153
             G   G  Q G  +  S   +   +SS
Sbjct: 903  QGSFPGMNQSGLMASSSPYSQPMNNSS 929



 Score = 94.0 bits (232), Expect = 2e-18
 Identities = 183/810 (22%), Positives = 275/810 (33%), Gaps = 88/810 (10%)

Query: 1801 GQSSSHGQHGSGSSQSSSYGQQ-----------GSGSGQSPSRGRHGSGSGHSSSYGQHG 1849
            G      QHG G+  S++ GQ            G      P  G    G       G  G
Sbjct: 93   GPDMEQPQHG-GAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALG 151

Query: 1850 SGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 1909
            +     +  G  G G      F ++  S+  +SG    G G      ++QHG +      
Sbjct: 152  TQQPPVAVPGG-GGGPAAVPEFNNYYGSAAPASG----GPGGRAGPCFDQHGGQQSPGM- 205

Query: 1910 GEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGS 1969
            G  H +S+ ++ + G       Q+   G   S     P  SR   G G G     G    
Sbjct: 206  GMMHSASAAAAGAPGS--MDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSG 263

Query: 1970 GSGWSSSRGPYESGSGH-SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSS 2028
            G G     G   +G+G  ++      + +G   G G  GSS+G+           G    
Sbjct: 264  GGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMG 323

Query: 2029 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSG-------QSPGHGQRGSGSR----- 2076
             G  GA+S   ++ G    G  + +G  +  SG+         SP    R  G       
Sbjct: 324  PGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYS 383

Query: 2077 ------QSPSYGRHGSGSGRSSSSGQH---GPGLGESSGFGHHESSSGQSSSYSQHGSGS 2127
                    PS  +  + +  +++ GQ    G GLG+  G  +  +S   +++  +    S
Sbjct: 384  SPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQR----S 439

Query: 2128 GHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGR 2187
              +   G  G   G+S               YG   +   Q         GS   P   R
Sbjct: 440  HPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQR 499

Query: 2188 HGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHF 2247
            +  G        Q  +    +  + P +  SG ++     E+       Y Q G     +
Sbjct: 500  YPIGI-------QGRTPGAMAGMQYPQQQDSGDAT---WKETFWLMPPQYGQQGVSG--Y 547

Query: 2248 CSQGQHGSTSGQSS------------TFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 2295
            C QGQ    S Q              +  Q+     Q  S   +G+ S    + G+    
Sbjct: 548  CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHE 607

Query: 2296 SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYT 2355
                  + R  S    S S     +G+  + SS    SGS  S G    + S+   S ++
Sbjct: 608  DLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQG----DQSNPAQSPFS 663

Query: 2356 QHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS-- 2413
             H   S H SS     S S   S    + S SG  S     GS         Q  S S  
Sbjct: 664  PH--ASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHP 721

Query: 2414 --GQSPSPSRGRHGSGSGQSSSYSPYG-SGSGWSSSRGPYESGSGHSSGLGHRESRSGQS 2470
               QSP P      +G+ ++   + YG   +G S S  P   G  H+     ++S S  S
Sbjct: 722  ALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNS--S 779

Query: 2471 SGYGQHGSSSGHSSTHGQHGSTSG-QSSSCGQHGASSGQSSSHGQHGSGSSQSSG---YG 2526
              YG   S  G    + +  + SG  S+S    G   G S+++  HG G SQ  G    G
Sbjct: 780  GTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLG 839

Query: 2527 RQGSGSGQS-PGHGQRGSGSRQSPSYGRHG 2555
            R  S   Q+ P  G   S +  SP   + G
Sbjct: 840  RMPSAGMQNRPFPGNMSSMTPSSPGMSQQG 869



 Score = 89.7 bits (221), Expect = 4e-17
 Identities = 302/1384 (21%), Positives = 453/1384 (32%), Gaps = 190/1384 (13%)

Query: 1422 GHSSSYEQHGSRSGQSSRGE----------RHGSSSGSSSSYGQHGSGSRQSLGHGQHGS 1471
            G      QHG     ++ G+          + G    +    G+   G  +  G G    
Sbjct: 93   GPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLG--AL 150

Query: 1472 GSGQSPSPSRGRHGSGSGQSSSYSPYGSGS----GWSSSRGPY--ESGSSHSSGLGHRES 1525
            G+ Q P    G  G  +      + YGS +    G     GP   + G   S G+G   S
Sbjct: 151  GTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHS 210

Query: 1526 RSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQH-GASSGQSSSHGQHGSGSSQSSG 1584
             S  ++G    GS     ++H  +      +S C  + G S   +   G  G G    SG
Sbjct: 211  ASAAAAG--APGSMDPLQNSHEGY-----PNSQCNHYPGYSRPGAGGGGGGGGGGGGGSG 263

Query: 1585 YGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS 1644
             G  G G+G + G G     +  + +    G G G                G+G   +  
Sbjct: 264  GGGGGGGAG-AGGAGAGAVAAAAAAAAAAAGGGGG---------------GGYGGSSAGY 307

Query: 1645 GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQ------ 1698
            G  SS  Q G G     G G   S S +++ G   G   R + +  QH SG+        
Sbjct: 308  GVLSSPRQQGGGMMMGPGGGGAASLS-KAAAGSAAGGFQRFAGQ-NQHPSGATPTLNQLL 365

Query: 1699 SSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHE 1758
            +S      S  G  P      +     S      + +G ++      +  G     G   
Sbjct: 366  TSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQY 425

Query: 1759 SGSGHSSAYSQHGSGSGHFCSQGQHGSTSG--QSSTFDQEGSSTGQSSSHGQHGSGSSQS 1816
            + +  + A +Q  S      S G  G T G  Q S  D       Q    G +     Q 
Sbjct: 426  AAASPAWAAAQQRSHPA--MSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQ 483

Query: 1817 SSYGQQGSGSGQSPSR------GR-HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSS 1869
            SS    GS     P R      GR  G+ +G      Q    + W  +        GQ  
Sbjct: 484  SSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQG 543

Query: 1870 GFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSG 1929
              G+ +    Q   Y+Q           +   S+S Q  + +Q  S  G       +G+ 
Sbjct: 544  VSGYCQQG--QQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEG-------YGTR 594

Query: 1930 SRQSLGHGQ---HGSGSGQSPSPSRGRHGSGS------GQSSSYGPYGSGSGWSSSRG-- 1978
            S+  L  G+         Q   PS     SGS      G  ++     S SG +SS+G  
Sbjct: 595  SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQ 654

Query: 1979 --PYES-----GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS-----ASGQS 2026
              P +S      S H S +    S S   S  G + S SG  S     GS       G  
Sbjct: 655  SNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQ 714

Query: 2027 SSCGQHGASSGQSSSHGQHG-----SGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSY 2081
            S    H A S QS    + G       + Q + YG Q +G   SP           SP  
Sbjct: 715  SESSSHPALS-QSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSP---------HPSPGG 764

Query: 2082 GRHG--SGSGRSSSSGQHGPGLGESSGFGHHES----SSGQSSSYSQHGSGSGHSSGYGQ 2135
              H   S   +S+SSG +GP + +    G++      S   S+SYS  G G G S+    
Sbjct: 765  QMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQM 824

Query: 2136 HGSRSGQSSRGERHG--SSSGSSSR--YGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSG 2191
            HG    Q       G   S+G  +R   G   S +  S G  +QG G G  P        
Sbjct: 825  HGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQG-GPGMGPPMPT---- 879

Query: 2192 SGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG-SGHSSAYSQHGSGSGHFCSQ 2250
                +   Q  + +   ++    +SR G  S  G ++SG    SS YSQ  + S    + 
Sbjct: 880  ---VNRKAQEAAAAVMQAAANSAQSRQG--SFPGMNQSGLMASSSPYSQPMNNSSSLMNT 934

Query: 2251 GQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSG 2310
             Q    S   +  +   +S G +       S          +  G+ Q  S+ +  S S 
Sbjct: 935  -QAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSST 993

Query: 2311 HSS-------SYGQHGSGSGW----SSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGS 2359
             +          G       W     +     GS        G      ++     +   
Sbjct: 994  TTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIG 1053

Query: 2360 GSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 2419
            G    +  ++    +   + G    ++S     Y Q+       +  G       + P P
Sbjct: 1054 GLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERG-------EEPPP 1106

Query: 2420 SRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGL----GHRESRSGQSSGYGQ 2475
                 G    Q     P  + SG  S +GP    S  S+ +    G  +  +  S+ +GQ
Sbjct: 1107 EVFSTGDTKKQPKLQPPSPANSG--SLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQ 1164

Query: 2476 -HGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ 2534
                  G SST   H   S  S S      S   ++ + Q   G S     GR      +
Sbjct: 1165 MTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQ---GMSMPDVMGRMPYEPNK 1221

Query: 2535 SPGHGQRGSGSRQSP--SYGRHGSGS-----GRSSSSGQHGSGLGESSGFGHHESSSGQS 2587
             P  G R       P  + G+  + S      +S S      G+G+   F +  S   + 
Sbjct: 1222 DPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRH 1281

Query: 2588 SSYSQHGSGSGHSSGYGQHGSRS----GQSSRGERH-------GSSSGSSSHYGQHGSGS 2636
              Y Q   G G  SG   +G        Q    +RH        +       Y    S  
Sbjct: 1282 EPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQ 1341

Query: 2637 RQS--SGHGRQGSGSGQSPSRGRHG--------SGLGHSSSHG----QHGSGSGRSSSRG 2682
            +Q   + +G   SG  + P +G++          G G   +HG      G     SSS G
Sbjct: 1342 QQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEG 1401

Query: 2683 PYES 2686
            P ++
Sbjct: 1402 PQQN 1405



 Score = 88.6 bits (218), Expect = 8e-17
 Identities = 223/933 (23%), Positives = 320/933 (34%), Gaps = 149/933 (15%)

Query: 1873 HHESSSWQSSGYTQHGSGSGHSSSYEQHGSR--SGQSSRGEQHGSSS--GSSSSYGQHGS 1928
            HH +   Q + + Q           +Q      S  +S G   G +   G      QHG 
Sbjct: 44   HHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHG- 102

Query: 1929 GSRQSLGHGQHGS---------GSGQSPSPSRGRHGSGSGQSSSYGPYGS--------GS 1971
            G++ S   GQ            G      P  G    G  +    G  G+        G 
Sbjct: 103  GAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGG 162

Query: 1972 GWSSSRGP-----YESGSGHSSGLGHRESRSGQSSGYGQHGS--SSGHSSTHGQHGSASG 2024
            G   +  P     Y S +  S G G R         + QHG   S G    H    +A+G
Sbjct: 163  GGGPAAVPEFNNYYGSAAPASGGPGGRAGPC-----FDQHGGQQSPGMGMMHSASAAAAG 217

Query: 2025 QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGS--GSRQSPSYG 2082
               S         Q+S  G   S  +   GY R G+G G   G G  G   G       G
Sbjct: 218  APGSMDPL-----QNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAG 272

Query: 2083 RHGSGSGR---SSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 2139
              G+G+G    ++++     G G   G+G   +  G  SS  Q G G     G G   S 
Sbjct: 273  AGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASL 332

Query: 2140 SGQSSRGERHGSSSGSSSRYG---QHGSGSRQS------SGHGRQGSGSGHSPSRGRHGS 2190
            S  ++     GS++G   R+    QH SG+  +      S      S  G  P      +
Sbjct: 333  SKAAA-----GSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSA 387

Query: 2191 GSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ 2250
                 S      + +G ++      +  G     G   + +  + A +Q  S      S 
Sbjct: 388  PPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPA--MSP 445

Query: 2251 GQHGSTSGQS--STFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSR------ 2302
            G  G T G+S  S  D       Q    G +     Q SS    GS     P R      
Sbjct: 446  GTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQ 505

Query: 2303 GRH-GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGS 2361
            GR  G+ +G      Q    + W  +        GQ    G+ +    Q   Y+Q     
Sbjct: 506  GRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQG--QQPYYSQQPQPP 563

Query: 2362 GHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSG---QSPS 2418
                  +   S+S Q  + ++  S  G       +G+ S+  L  G+         Q   
Sbjct: 564  HLPPQAQYLPSQSQQRYQPQQDMSQEG-------YGTRSQPPLAPGKPNHEDLNLIQQER 616

Query: 2419 PSRGRHGSGS------GQSSSYSPYGSGSGWSSSRG----PYES-----GSGHSSGLGHR 2463
            PS     SGS      G  ++ S   S SG +SS+G    P +S      S H S +   
Sbjct: 617  PSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGG 676

Query: 2464 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSS 2523
             S S   S  G + S SG  S     GS         Q   S  +SSSH           
Sbjct: 677  PSPSPVGSPVGSNQSRSGPISPASIPGSQMPP-----QPPGSQSESSSH----------- 720

Query: 2524 GYGRQGSGSGQSPGHGQRG--SGSRQSPS---YGRHGSGSGRS---SSSGQHGSGL---- 2571
                      QSP   +RG  +G++++P    YG   +G   S   S  GQ  +G+    
Sbjct: 721  ------PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQ 774

Query: 2572 -GESSG-FGHHESSSGQSSSYSQHGSGSG-HSSGYGQHGSRSGQSSRGERHGSSSGSSSH 2628
               SSG +G   S  G   +YS+  + SG  S+ Y   G   G S+  + HG   G S  
Sbjct: 775  QSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHG--QGPSQP 832

Query: 2629 YGQHGSGSRQSSG------HGRQGSGSGQSPSRGRHGS-GLGHS----SSHGQHGSGSGR 2677
             G    G   S+G       G   S +  SP   + G  G+G      +   Q  + +  
Sbjct: 833  CGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVM 892

Query: 2678 SSSRGPYESRLGHSSVFGQHESG-SGHSSAYSQ 2709
             ++    +SR G  S  G ++SG    SS YSQ
Sbjct: 893  QAAANSAQSRQG--SFPGMNQSGLMASSSPYSQ 923



 Score = 79.7 bits (195), Expect = 4e-14
 Identities = 152/731 (20%), Positives = 231/731 (31%), Gaps = 116/731 (15%)

Query: 169 HNSYSGQSSSYGEQN--SDSHQSSGRGQCGSGSGQS-PNYGQHGSGSGQSSSNDTHGSGS 225
           H++ +  + + G  +   +SH+     QC    G S P  G  G G G        G G 
Sbjct: 209 HSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGG 268

Query: 226 GQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ 285
           G +        +   ++  +   +G G   GYG  GS +G        +   G     G 
Sbjct: 269 GGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYG--GSSAGYGVLSSPRQQGGGMMMGPGG 326

Query: 286 HGSGSRQSLGHGRQGSGSRQSPSHVRHGSGS----------------GHSSSHGQHGSGS 329
            G+ S      G    G ++     +H SG+                 +  S+ ++ S S
Sbjct: 327 GGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPS 386

Query: 330 ----------SYSYSRGHYESGSGQTSGFGQHESGSGQ----SSGYSKHGSGSGHSSSQG 375
                     S + + G    G    +G G  +    Q    S  ++     S  + S G
Sbjct: 387 APPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPG 446

Query: 376 QHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGS--------------G 421
             G T G++  S       ++   YG   +          +  GS              G
Sbjct: 447 TPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQG 506

Query: 422 QSPG-------HGQRGSGSG--------QSPSSGQHGTGFGRSSSSGPYVS--------- 457
           ++PG         Q+ SG            P  GQ G          PY S         
Sbjct: 507 RTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP 566

Query: 458 -GSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSS 516
             + Y           +       +G+ S      G+         + ER  S    S S
Sbjct: 567 PQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGS 626

Query: 517 YGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES 576
                +G+  +L  +   SGS  S      + +  +   S + PH      S   GP  S
Sbjct: 627 IDDLPTGTEATLSSAVSASGSTSS------QGDQSNPAQSPFSPHASPHLSSIPGGPSPS 680

Query: 577 GSGHSSGLGHQESRSGQSSGYGQHGSS-----SGHSSTHGQHGSTSGQSSSCGQHGATSG 631
             G  S +G  +SRSG  S     GS       G  S    H + S QS    + G  +G
Sbjct: 681 PVG--SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALS-QSPMPQERGFMAG 737

Query: 632 QSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWS---SSN 688
                      + Q ++YG Q +G   SP     G      SS+ Q  S   +    S  
Sbjct: 738 TQR--------NPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQY 789

Query: 689 GPHGSVS--------GQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHG--------SR 732
           GP G+ S          +S  G   G G S+    HG G S   G    G        +R
Sbjct: 790 GPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR 849

Query: 733 SGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHG 792
               + S    SS G+S   G  G G    + + +    +        + + S   S  G
Sbjct: 850 PFPGNMSSMTPSSPGMSQQ-GGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPG 908

Query: 793 QHGSGTSCSSS 803
            + SG   SSS
Sbjct: 909 MNQSGLMASSS 919



 Score = 78.6 bits (192), Expect = 8e-14
 Identities = 186/865 (21%), Positives = 278/865 (32%), Gaps = 120/865 (13%)

Query: 1999 QSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 2058
            Q   +  H     H + H  H  A  Q  +  Q      Q     Q       S+     
Sbjct: 24   QQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLG 83

Query: 2059 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH---GPGLGESSGFGHHESSSG 2115
            G+G G +P  G       + P +G    G+  S++ GQ    GP L    G         
Sbjct: 84   GAGGG-APQPGP----DMEQPQHG----GAKDSAAGGQADPPGPPLLSKPG-----DEDD 129

Query: 2116 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQ 2175
                  +   G     G G  G++    +     G  +        +GS +  S G G +
Sbjct: 130  APPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGR 189

Query: 2176 GSGSGHSPSRGRHGS--GSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 2233
                   P   +HG     G    H    + +G   S  P ++     S  G   S   H
Sbjct: 190  AG-----PCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQN-----SHEGYPNSQCNH 239

Query: 2234 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQG 2293
               YS+ G+G G     G  G + G        G   G + + G      + +++     
Sbjct: 240  YPGYSRPGAGGGGGGGGGGGGGSGG--------GGGGGGAGAGGAGAGAVAAAAAAAAAA 291

Query: 2294 SGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 2353
            +G G     G   +G G  SS  Q G G       G  G+ S   +  G       + +G
Sbjct: 292  AGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGG--GAASLSKAAAGSAAGGFQRFAG 349

Query: 2354 YTQHGSGS----------------GHSSSYEQHGSRSGQS---SRGERHGSSSGSSSSYG 2394
              QH SG+                 +  SY ++ S S      S+ +   +++G+++   
Sbjct: 350  QNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ 409

Query: 2395 QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGS 2454
            Q  +G    LG       +  SP+ +  +  S    S        G    S   P     
Sbjct: 410  QAAAG--MGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467

Query: 2455 GHSSGLGHR-ESRSGQSSGY--GQHGSSSGHSSTHGQHGSTSGQSSSCGQ-HGASSGQSS 2510
                G+G    S+  QSS Y  G +G         G  G T G  +         SG ++
Sbjct: 468  PQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDAT 527

Query: 2511 ----------SHGQHGSGSSQSSGYGRQGSGSGQS---------------PGHGQRGSGS 2545
                       +GQ G      SGY +QG     S               P   Q+    
Sbjct: 528  WKETFWLMPPQYGQQGV-----SGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQP 582

Query: 2546 RQSPSYGRHGSGSGRSSSSG------------QHGSGLGESSGFGHHESSSGQSSSYSQH 2593
            +Q  S   +G+ S    + G            +  S L + SG    +  +G  ++ S  
Sbjct: 583  QQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSG-SIDDLPTGTEATLSSA 641

Query: 2594 GSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSP 2653
             S SG +S  G   + +   S    H S   SS   G   S S   S  G   S SG   
Sbjct: 642  VSASGSTSSQGDQSNPA--QSPFSPHASPHLSSIPGGP--SPSPVGSPVGSNQSRSGPIS 697

Query: 2654 SRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSG 2713
                 GS +       Q  S S  + S+ P     G  +       G+  +   +Q+G  
Sbjct: 698  PASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMA-------GTQRNPQMAQYGPQ 750

Query: 2714 SGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSG-QSLSH 2772
                 S   H S  GQ          +  S +YG + S       Y R  A SG  S S+
Sbjct: 751  QTG-PSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASY 809

Query: 2773 GRHGSGSGQSSSYGQHGSGSGQSSG 2797
               G G G S++   HG G  Q  G
Sbjct: 810  SGPGPGMGISANNQMHGQGPSQPCG 834



 Score = 78.2 bits (191), Expect = 1e-13
 Identities = 189/851 (22%), Positives = 268/851 (31%), Gaps = 121/851 (14%)

Query: 1522 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHG-----QHG 1576
            H  S +    G G      G      QHG          +  A+ GQ+   G     + G
Sbjct: 74   HPISNNNSLGGAGGGAPQPGPDMEQPQHGGA--------KDSAAGGQADPPGPPLLSKPG 125

Query: 1577 SGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSS---SGQHGSGLGE 1633
                     G    G  + PG G  G+   Q P     G G G ++    +  +GS    
Sbjct: 126  DEDDAPPKMGEPAGGRYEHPGLGALGT---QQPPVAVPGGGGGPAAVPEFNNYYGSAAPA 182

Query: 1634 SSGFGHHESSS-GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSS------ 1686
            S G G        Q       G G  HS+     G+          H     S       
Sbjct: 183  SGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPG 242

Query: 1687 -SRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYE 1745
             SR G  G G     G G  G G G   + G  G+G G  ++     + +      G Y 
Sbjct: 243  YSRPGAGGGGGGGGGGGGGSGGGGGGGGA-GAGGAGAGAVAAAAAAAAAAAGGGGGGGYG 301

Query: 1746 SRSGHSSVFGQHES---------GSGHSSAYSQHGSGSG-----HFCSQGQHGSTSGQSS 1791
              S    V               G G +++ S+  +GS       F  Q QH   SG + 
Sbjct: 302  GSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQH--PSGATP 359

Query: 1792 TFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSG 1851
            T +Q    T  S     +G    + SS     S     PS+ +  + +  +++ GQ  + 
Sbjct: 360  TLNQ--LLTSPSPMMRSYGGSYPEYSS----PSAPPPPPSQPQSQAAAAGAAAGGQQAAA 413

Query: 1852 SGWSSSSGRHGSGSGQSSGFGHHESS-SWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRG 1910
                      G G G+  G  +  +S +W ++    H + S                + G
Sbjct: 414  ----------GMGLGKDMGAQYAAASPAWAAAQQRSHPAMS--------------PGTPG 449

Query: 1911 EQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSG 1970
               G S GS              +G   H      SP P  G +G    Q    G  G  
Sbjct: 450  PTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPG-GSYGPPGPQRYPIGIQGRT 508

Query: 1971 SG-WSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSC 2029
             G  +  + P +  SG ++    +E+       YGQ G S         + S   Q    
Sbjct: 509  PGAMAGMQYPQQQDSGDAT---WKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHL 565

Query: 2030 GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG--SGQSPGHGQRGSGSRQSPSYGRHGSG 2087
                      S             GYG +     +   P H       ++ PS     SG
Sbjct: 566  PPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSG 625

Query: 2088 SGRSSSSGQHGPGLGESSGFGHHESSSGQS----SSYSQHG-----------SGSGHSSG 2132
            S     +G         S  G   S   QS    S +S H            S S   S 
Sbjct: 626  SIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSP 685

Query: 2133 YGQHGSRSGQSSRGERHGSS-----SGSSSRYGQHGSGSRQSSGHGRQ-GSGSGHSPSRG 2186
             G + SRSG  S     GS       GS S    H + S+      R   +G+  +P   
Sbjct: 686  VGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMA 745

Query: 2187 RHG------SGSGHSSSHGQHGSG------SGRSSSRGPYESRSGHSSVFGQHESGSG-H 2233
            ++G      S S H S  GQ  +G      S  S + GP  S+ G    + +  + SG  
Sbjct: 746  QYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVP 805

Query: 2234 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEG--SSTGQSSS--HGQHGSGSSQSSSY 2289
            S++YS  G G G   +   HG    Q       G   S G  +    G   S +  S   
Sbjct: 806  SASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGM 865

Query: 2290 GQQGSGSGQSP 2300
             QQG G G  P
Sbjct: 866  SQQG-GPGMGP 875



 Score = 77.4 bits (189), Expect = 2e-13
 Identities = 172/755 (22%), Positives = 248/755 (32%), Gaps = 114/755 (15%)

Query: 2135 QHGSRSGQSSRGE----------RHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPS 2184
            QHG     ++ G+          + G    +  + G+   G  +  G G  G+       
Sbjct: 100  QHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAV 159

Query: 2185 RGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS 2244
             G  G  +     +  +GS +  S   G    R+G    F QH    G  S     G G 
Sbjct: 160  PGGGGGPAAVPEFNNYYGSAAPASGGPG---GRAG--PCFDQH---GGQQSP----GMGM 207

Query: 2245 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGR 2304
             H  S    G+          + S  G  +S   H  G S+  + G  G G G     G 
Sbjct: 208  MHSASAAAAGAPGSMDPL---QNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGG 264

Query: 2305 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHS 2364
             G G G     G  G+G+G  +++    + +    G G          GY    +G G  
Sbjct: 265  GGGGGGA----GAGGAGAGAVAAAAAAAAAAAGGGGGG----------GYGGSSAGYGVL 310

Query: 2365 SSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ-------SP 2417
            SS  Q G        G   G++S S ++ G    G ++  G  QH SG+         SP
Sbjct: 311  SSPRQQGGGMMMGPGGG--GAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSP 368

Query: 2418 SPSRGRHGSGSGQSSSYS----PYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQ---- 2469
            SP    +G    + SS S    P       +++ G    G   ++G+G  +    Q    
Sbjct: 369  SPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAA 428

Query: 2470 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSC---------------GQHGASSGQSSSH-- 2512
            S  +      S  + + G  G T G+S                  G +  S  Q SS   
Sbjct: 429  SPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYP 488

Query: 2513 -GQHGSGSSQSSGYGRQGSGSGQSPGHG---QRGSGSR--------QSPSYGRHG----- 2555
             G +G    Q    G QG   G   G     Q+ SG            P YG+ G     
Sbjct: 489  GGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYC 548

Query: 2556 -SGSGRSSSSGQHGSGLGESSGFGHHESSSG----QSSSYSQHGSGSGHSSGYGQHGSRS 2610
              G     S       L   + +   +S       Q  S   +G+ S      G+     
Sbjct: 549  QQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHED 608

Query: 2611 GQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQ 2670
                + ER  S    S       +G+  +       SGS  S     + +     S    
Sbjct: 609  LNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPA----QSPFSP 664

Query: 2671 HGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS--- 2727
            H S    S   GP  S +G  S  G ++S SG  S  S  GS         Q  S+S   
Sbjct: 665  HASPHLSSIPGGPSPSPVG--SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPA 722

Query: 2728 -GQSSTFDQEGSSTG-----QSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQ 2781
              QS    + G   G     Q + YG + +G S S     H +  GQ  +       S  
Sbjct: 723  LSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSP----HPSPGGQMHAGISSFQQSNS 778

Query: 2782 SSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGG 2816
            S +YG   S  G    YS+  + SG    SY   G
Sbjct: 779  SGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPG 813



 Score = 77.4 bits (189), Expect = 2e-13
 Identities = 198/851 (23%), Positives = 288/851 (33%), Gaps = 85/851 (9%)

Query: 179 YGEQNSDSHQSSGR-GQCGS--GSGQSPNYGQHGSGSGQSSS---------NDTHGSGSG 226
           YG     S    GR G C    G  QSP  G   S S  ++          N   G  + 
Sbjct: 176 YGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNS 235

Query: 227 QSSGFSQHKSSSGQSSGYSQHGSGSGHS-SGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ 285
           Q + +  + S  G   G    G G G S  G G  G+ +G +  G    +++ ++++ G 
Sbjct: 236 QCNHYPGY-SRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGG 294

Query: 286 HGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQT 345
            G G     G    G G   SP       G G     G  G+ S    + G    G  + 
Sbjct: 295 GGGG---GYGGSSAGYGVLSSPRQ----QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRF 347

Query: 346 SGFGQHESGSGQSSGY---SKHGSGSGHSSSQGQHGSTSGQASSSGQ-HGSSSRQSSSYG 401
           +G  QH SG+  +      S       +  S  ++ S S       Q    ++   ++ G
Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407

Query: 402 QHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSS--GPYVSGS 459
             ++A+    G+   +  +  SP        S  + S G  G   GRS  S   P V   
Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467

Query: 460 GYSSGFGHH-ESSSEHSSGYT--QHGSGSGHSSGHGQHGSRSG-----QSSRGERQGSSA 511
               G G +  S  + SS Y    +G         G  G   G     Q  + +  G + 
Sbjct: 468 PQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDAT 527

Query: 512 GSSS------SYGQHGSGSRQSLGHSRHGSGSGQSPS--------PSRGRHESGSRQSSS 557
              +       YGQ G       G   + S   Q P         PS+ +     +Q  S
Sbjct: 528 WKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMS 587

Query: 558 YGPHGYGSGRSSSRGPYESGSGHSSGLG--HQESRSGQSSGYGQ-HGSSSGHSSTHGQHG 614
               GYG   + S+ P   G  +   L    QE  S      G      +G  +T     
Sbjct: 588 --QEGYG---TRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAV 642

Query: 615 STSGQSSSCGQHG--ATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFG-H 671
           S SG +SS G     A S  S     H S           GS  G + SR    S     
Sbjct: 643 SASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIP 702

Query: 672 SSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGS 731
            S       GS   SS+ P  S S      G  +G+ ++   +Q+G   +  S    H S
Sbjct: 703 GSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPS-MSPHPS 761

Query: 732 RSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSG-HSPSRVRHGSSSGHSSS 790
             GQ          S  S +YG   S       + R  + SG  S S    G   G S++
Sbjct: 762 PGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISAN 821

Query: 791 HGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQ 850
           +  HG G   S  CG    G   ++G  Q+    G   S   S+ G  S QG  G     
Sbjct: 822 NQMHGQGP--SQPCGAVPLGRMPSAGM-QNRPFPGNMSSMTPSSPG-MSQQGGPGMGPPM 877

Query: 851 SSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSP-SYGRH 909
            +      +   Q ++    ++A++ A  R       G  PG  Q G  +  SP S   +
Sbjct: 878 PTV-----NRKAQEAAAAVMQAAANSAQSR------QGSFPGMNQSGLMASSSPYSQPMN 926

Query: 910 GSGSGRSSSSGRHG------SGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSR 963
            S S  ++ +  +       + S  S G     S G+S          G      Q  S+
Sbjct: 927 NSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESK-LPLPLKADGKEEGTPQPESK 985

Query: 964 SGQSSRSEQHG 974
           S +SS S   G
Sbjct: 986 SKKSSSSTTTG 996



 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 101/461 (21%), Positives = 151/461 (32%), Gaps = 34/461 (7%)

Query: 2219 GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQ 2278
            G +     H+    H  A+  H     H      H +   Q + F Q+     Q     Q
Sbjct: 15   GEAPAAPPHQQHHHHHHAHHHHH----HAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQ 70

Query: 2279 HGSGS-SQSSSYGQQGSGSGQ-SPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 2336
                  S ++S G  G G+ Q  P   +   G    S+ G      G    S + G    
Sbjct: 71   QQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS-KPGDEDD 129

Query: 2337 QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQH 2396
                 G      ++  G    G+     +     G  +        +GS++ +S      
Sbjct: 130  APPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG----- 184

Query: 2397 GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGH 2456
            G G R      QHG   GQ  SP  G   S S  ++  +P       +S  G   S   H
Sbjct: 185  GPGGRAGPCFDQHG---GQQ-SPGMGMMHSASAAAAG-APGSMDPLQNSHEGYPNSQCNH 239

Query: 2457 SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHG 2516
              G     +  G   G G  G S G     G     +G  +      A++  +   G  G
Sbjct: 240  YPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGG 299

Query: 2517 SGSSQSSGYG------RQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSG 2570
             G S S+GYG      +QG G    PG G  G+ S    + G    G  R +   QH SG
Sbjct: 300  YGGS-SAGYGVLSSPRQQGGGMMMGPGGG--GAASLSKAAAGSAAGGFQRFAGQNQHPSG 356

Query: 2571 LGE------SSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSG 2624
                     +S      S  G    YS   +     S      + +G ++ G++  +  G
Sbjct: 357  ATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMG 416

Query: 2625 SSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHS 2665
                 G   + +  +    +Q S    SP  G  G  +G S
Sbjct: 417  LGKDMGAQYAAASPAWAAAQQRSHPAMSP--GTPGPTMGRS 455



 Score = 58.9 bits (141), Expect = 7e-08
 Identities = 198/887 (22%), Positives = 292/887 (32%), Gaps = 126/887 (14%)

Query: 248  GSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGS------ 301
            G+ +  SS     GS S Q  +      S+ + S +  H S    S+  G   S      
Sbjct: 633  GTEATLSSAVSASGSTSSQGDQ------SNPAQSPFSPHASPHLSSIPGGPSPSPVGSPV 686

Query: 302  GSRQSPSH-VRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSG 360
            GS QS S  +   S  G        GS S  S      +S   Q  GF      + Q + 
Sbjct: 687  GSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQ 746

Query: 361  YSKHGSG---SGHSSSQGQ-HGSTSG--QASSSGQHGSSSRQSSSYGQHESASRHSSGRG 414
            Y    +G   S H S  GQ H   S   Q++SSG +G    Q S YG   + SR  +  G
Sbjct: 747  YGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGP---QMSQYGPQGNYSRPPAYSG 803

Query: 415  QHSSG-SGQSPGHGQRGSGS--GQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESS 471
              S+  SG  PG G   +    GQ PS        GR  S+G  +    +    G+  S 
Sbjct: 804  VPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAG--MQNRPFP---GNMSSM 858

Query: 472  SEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHS 531
            +  S G +Q G            G      +   +   +A +      + + SRQ     
Sbjct: 859  TPSSPGMSQQGGP----------GMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPG 908

Query: 532  RHGSGSGQSPSP-SRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESR 590
             + SG   S SP S+  + S S  ++   P+       +S          ++ +G  +  
Sbjct: 909  MNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSS---------AASVGLADMM 959

Query: 591  SGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRY- 649
            S   S       + G      Q  S S +SSS    G    +    G          RY 
Sbjct: 960  SPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYL 1019

Query: 650  ---GQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSS-GFGHKS 705
                ++GS     P+ G+   D        +   G    + N     ++   + G    +
Sbjct: 1020 TFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSA 1079

Query: 706  GSGQSSGYSQH--------GSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGS 757
             S     Y Q+          G          G    Q        ++SG        G 
Sbjct: 1080 ASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSG-----SLQGP 1134

Query: 758  GSHQSSGHGRQGSGSGH----SPSRVRHGSSS----GHSSSHGQHGSGTSCSSSC----- 804
             + QS+G        G     +P+   HG  +    G SS+   H   +  S S      
Sbjct: 1135 QTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRN 1194

Query: 805  -----GHYESGSGQASGFGQHESGSGQ----GYSQHGSASGHFSSQGRHGSTS-----GQ 850
                   Y+ G       G+      +    G  +   +S  F +QG+  ++S      Q
Sbjct: 1195 SMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQ 1254

Query: 851  SSSSGQHDSSSGQSSS--YGQHESASHHASGRGRHGSG--SGQSPGHGQRGSGSGQSPSY 906
            S S    +   GQ     YG      H   G+   G G  SGQ P  G +     Q P+Y
Sbjct: 1255 SPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNY 1314

Query: 907  GRHGSGSGRSSSSGRHGSGSGQSSG--FGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRS 964
             RH          G +G  + +  G  +  + SS Q   Y Q+G            GS S
Sbjct: 1315 KRH--------MDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYG------------GSYS 1354

Query: 965  GQSSRSEQHGSSSGSSSSYGQHGSGSRQSLG-HGQHGSGSGQSPSPSRGRHGSGSGQSSS 1023
            G   R  Q G      S     G G  Q+ G   Q   G  QS S    +    + ++  
Sbjct: 1355 GPDRRPIQ-GQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDM 1413

Query: 1024 YGPY--RSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGS 1068
              PY  R G G  +   PY  G   +  +   + R    S +  H S
Sbjct: 1414 PYPYQNRQGPGGPTQAPPY-PGMNRTDDMMVPDQRINHESQWPSHVS 1459



 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 84/399 (21%), Positives = 128/399 (32%), Gaps = 67/399 (16%)

Query: 2469 QSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 2528
            Q   +  H     H + H  H     Q  +  Q      Q     Q       S+     
Sbjct: 24   QQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLG 83

Query: 2529 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH---GSGLGESSGFGHHESSSG 2585
            G+G G +P  G       + P +G    G+  S++ GQ    G  L    G         
Sbjct: 84   GAGGG-APQPGP----DMEQPQHG----GAKDSAAGGQADPPGPPLLSKPG-----DEDD 129

Query: 2586 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHG-R 2644
                  +   G     G G  G++    +     G  +        +GS +  S G G R
Sbjct: 130  APPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGR 189

Query: 2645 QGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHS 2704
             G    Q   +   G G+ HS+S     + +G   S  P ++     S  G   S   H 
Sbjct: 190  AGPCFDQHGGQQSPGMGMMHSAS----AAAAGAPGSMDPLQN-----SHEGYPNSQCNHY 240

Query: 2705 SAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGA 2764
              YS+ G+G G        G   G        G  +G     G  G+G + +       A
Sbjct: 241  PGYSRPGAGGG--------GGGGGGG------GGGSGGGGGGGGAGAGGAGAGAVAAAAA 286

Query: 2765 GSGQSLSHGRHGSGSGQSSSYG------------QHGSGSGQSSGYSQHGSGSGQDGYSY 2812
             +  +   G  G   G S+ YG              G G G ++  S+  +GS   G+  
Sbjct: 287  AAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQR 346

Query: 2813 CKGGSNHDGGSS--------------GSYFLSFPSSTSP 2837
              G + H  G++               SY  S+P  +SP
Sbjct: 347  FAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSP 385



 Score = 48.5 bits (114), Expect = 9e-05
 Identities = 83/328 (25%), Positives = 112/328 (34%), Gaps = 59/328 (17%)

Query: 1450 SSSYGQHGSGSRQSLGHGQHGSGSG--QSPSPSRGRHGSGS----GQSSSYSPYGSGSGW 1503
            ++S    G  + QS G        G  + P+P+   HG  +    G+SS+ S +   S  
Sbjct: 1126 ANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDV 1185

Query: 1504 SSS----------RGPYESGSSHSSGLGHR--ESRSGQSSGYGQHGSSSGHSSTHGQHGS 1551
            S S            PY+ G S    +G    E       G  +   SS    T GQ  +
Sbjct: 1186 SDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPN 1245

Query: 1552 TS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ----GSGSGQSPGHGQRG 1602
            +S      QS S        GQ        S   +   YG+Q    G  SGQ P  G + 
Sbjct: 1246 SSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQP 1305

Query: 1603 SGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 1662
                Q P+Y RH  G     +    G          + + SS Q   Y+Q+G        
Sbjct: 1306 GLYPQQPNYKRHMDGMYGPPAKRHEGD-------MYNMQYSSQQQEMYNQYG-------- 1350

Query: 1663 YGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL 1722
                GS SG   R    G      SR    G G  Q+ G   Q             G  L
Sbjct: 1351 ----GSYSGPDRR-PIQGQYPYPYSRERMQGPGQIQTHGIPPQ-----------MMGGPL 1394

Query: 1723 GHSSSHG-QHGSGSGRSSSRGPYESRSG 1749
              SSS G Q    + R+    PY++R G
Sbjct: 1395 QSSSSEGPQQNMWAARNDMPYPYQNRQG 1422



 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 81/328 (24%), Positives = 111/328 (33%), Gaps = 59/328 (17%)

Query: 1920 SSSYGQHGSGSRQSLGHGQHGSGSG--QSPSPSRGRHGSGS----GQSSSYGPYGSGSGW 1973
            ++S    G  + QS G        G  + P+P+   HG  +    G+SS+   +   S  
Sbjct: 1126 ANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDV 1185

Query: 1974 SSS----------RGPYESGSGHSSGLGHR--ESRSGQSSGYGQHGSSSGHSSTHGQHGS 2021
            S S            PY+ G      +G    E       G  +   SS    T GQ  +
Sbjct: 1186 SDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPN 1245

Query: 2022 AS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ----GSGSGQSPGHGQRG 2072
            +S      QS S        GQ        S   +   YG+Q    G  SGQ P  G + 
Sbjct: 1246 SSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQP 1305

Query: 2073 SGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHH-ESSSGQSSSYSQHGSGSGHSS 2131
                Q P+Y RH          G +GP      G  ++ + SS Q   Y+Q+G       
Sbjct: 1306 GLYPQQPNYKRH--------MDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYG------- 1350

Query: 2132 GYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSG 2191
                 GS SG   R    G      SR    G G  Q+ G   Q  G          G  
Sbjct: 1351 -----GSYSGPDRR-PIQGQYPYPYSRERMQGPGQIQTHGIPPQMMG----------GPL 1394

Query: 2192 SGHSSSHGQHGSGSGRSSSRGPYESRSG 2219
               SS   Q    + R+    PY++R G
Sbjct: 1395 QSSSSEGPQQNMWAARNDMPYPYQNRQG 1422



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 81/328 (24%), Positives = 110/328 (33%), Gaps = 59/328 (17%)

Query: 2390 SSSYGQHGSGSRQSLGHGQHGSGSG--QSPSPSRGRHGSGS----GQSSSYSPYGSGSGW 2443
            ++S    G  + QS G        G  + P+P+   HG  +    G+SS+ S +   S  
Sbjct: 1126 ANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDV 1185

Query: 2444 SSS----------RGPYESGSGHSSGLGHR--ESRSGQSSGYGQHGSSSGHSSTHGQHGS 2491
            S S            PY+ G      +G    E       G  +   SS    T GQ  +
Sbjct: 1186 SDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPN 1245

Query: 2492 TS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ----GSGSGQSPGHGQRG 2542
            +S      QS S        GQ        S   +   YG+Q    G  SGQ P  G + 
Sbjct: 1246 SSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQP 1305

Query: 2543 SGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 2602
                Q P+Y RH  G     +    G          + + SS Q   Y+Q+G        
Sbjct: 1306 GLYPQQPNYKRHMDGMYGPPAKRHEGD-------MYNMQYSSQQQEMYNQYG-------- 1350

Query: 2603 YGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL 2662
                GS SG   R    G      S     G G  Q+ G   Q             G  L
Sbjct: 1351 ----GSYSGPDRR-PIQGQYPYPYSRERMQGPGQIQTHGIPPQ-----------MMGGPL 1394

Query: 2663 GHSSSHG-QHGSGSGRSSSRGPYESRLG 2689
              SSS G Q    + R+    PY++R G
Sbjct: 1395 QSSSSEGPQQNMWAARNDMPYPYQNRQG 1422



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 82/330 (24%), Positives = 109/330 (33%), Gaps = 47/330 (14%)

Query: 962  SRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQS 1021
            S S Q  ++ Q   S+  +   G     +  S  HGQ     G   S +   H   S  S
Sbjct: 1128 SGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQG-GRSSTISVHDPFSDVS 1186

Query: 1022 SSYGPYRSGSGWSSSRGPYESGSGHSSGLGHR--ESRSGQSSGYGQHGSSSGHSSTHGQH 1079
             S  P R+     +   PY+ G      +G    E       G  +   SS    T GQ 
Sbjct: 1187 DSSFPKRNSM---TPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQM 1243

Query: 1080 GSTS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ----GSGSGQSPGHGQ 1130
             ++S      QS S        GQ        S   +   YG+Q    G  SGQ P  G 
Sbjct: 1244 PNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGH 1303

Query: 1131 RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 1190
            +     Q P+Y RH  G     +    G          + + SS Q   Y+Q+G      
Sbjct: 1304 QPGLYPQQPNYKRHMDGMYGPPAKRHEGD-------MYNMQYSSQQQEMYNQYG------ 1350

Query: 1191 SGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGS 1250
                  GS SG   R    G      S     G G  Q+ G   Q             G 
Sbjct: 1351 ------GSYSGPDRR-PIQGQYPYPYSRERMQGPGQIQTHGIPPQ-----------MMGG 1392

Query: 1251 GLGHSSSHG-QHGSGSGRSSSRGPYESRSG 1279
             L  SSS G Q    + R+    PY++R G
Sbjct: 1393 PLQSSSSEGPQQNMWAARNDMPYPYQNRQG 1422


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.299    0.118    0.343 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 140,478,549
Number of Sequences: 37866
Number of extensions: 9180416
Number of successful extensions: 254266
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 375
Number of HSP's successfully gapped in prelim test: 1080
Number of HSP's that attempted gapping in prelim test: 54283
Number of HSP's gapped (non-prelim): 66283
length of query: 2850
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2730
effective length of database: 13,703,598
effective search space: 37410822540
effective search space used: 37410822540
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.6 bits)
S2: 71 (32.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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