Guide to the Human Genome
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Search of human proteins with 57634536

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|57634536 La ribonucleoprotein domain family, member 4B [Homo
sapiens]
         (738 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|57634536 La ribonucleoprotein domain family, member 4B [Homo ...  1484   0.0  
gi|40353738 c-Mpl binding protein isoform a [Homo sapiens]            421   e-117
gi|40353740 c-Mpl binding protein isoform b [Homo sapiens]            420   e-117
gi|40353736 c-Mpl binding protein isoform c [Homo sapiens]            253   4e-67
gi|61102725 la related protein isoform 2 [Homo sapiens]                55   2e-07
gi|39725634 la related protein isoform 1 [Homo sapiens]                55   2e-07
gi|30061565 La ribonucleoprotein domain family member 2 isoform ...    53   1e-06
gi|30061569 La ribonucleoprotein domain family member 2 isoform ...    53   1e-06
gi|30061567 La ribonucleoprotein domain family member 2 isoform ...    53   1e-06
gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]            49   2e-05
gi|109809739 La ribonucleoprotein domain family, member 7 [Homo ...    48   3e-05
gi|109809741 La ribonucleoprotein domain family, member 7 [Homo ...    48   3e-05
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         47   5e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    47   6e-05
gi|47933339 RNA binding motif protein 15 [Homo sapiens]                44   5e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        44   5e-04
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   43   0.001
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   43   0.001
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   43   0.001
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    43   0.001
gi|193083183 synaptopodin 2 isoform a [Homo sapiens]                   43   0.001
gi|153792780 additional sex combs like 2 [Homo sapiens]                43   0.001
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    43   0.001
gi|119943102 CREB binding protein isoform b [Homo sapiens]             43   0.001
gi|119943104 CREB binding protein isoform a [Homo sapiens]             43   0.001
gi|58530845 zyxin [Homo sapiens]                                       43   0.001
gi|4508047 zyxin [Homo sapiens]                                        43   0.001
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    42   0.002
gi|157074225 nuclear pore complex interacting protein-like 3 [Ho...    42   0.002
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             42   0.003

>gi|57634536 La ribonucleoprotein domain family, member 4B [Homo
           sapiens]
          Length = 738

 Score = 1484 bits (3841), Expect = 0.0
 Identities = 738/738 (100%), Positives = 738/738 (100%)

Query: 1   MTSDQDAKVVAEPQTQRVQEGKDSAHLMNGPISQTTSQTSSIPPLSQVPATKVSELNPNA 60
           MTSDQDAKVVAEPQTQRVQEGKDSAHLMNGPISQTTSQTSSIPPLSQVPATKVSELNPNA
Sbjct: 1   MTSDQDAKVVAEPQTQRVQEGKDSAHLMNGPISQTTSQTSSIPPLSQVPATKVSELNPNA 60

Query: 61  EVWGAPVLHLEASSAADGVSAAWEEVAGHHADRGPQGSDANGDGDQGHENAALPDPQESD 120
           EVWGAPVLHLEASSAADGVSAAWEEVAGHHADRGPQGSDANGDGDQGHENAALPDPQESD
Sbjct: 61  EVWGAPVLHLEASSAADGVSAAWEEVAGHHADRGPQGSDANGDGDQGHENAALPDPQESD 120

Query: 121 PADMNALALGPSEYDSLPENSETGGNESQPDSQEDPREVLKKTLEFCLSRENLASDMYLI 180
           PADMNALALGPSEYDSLPENSETGGNESQPDSQEDPREVLKKTLEFCLSRENLASDMYLI
Sbjct: 121 PADMNALALGPSEYDSLPENSETGGNESQPDSQEDPREVLKKTLEFCLSRENLASDMYLI 180

Query: 181 SQMDSDQYVPITTVANLDHIKKLSTDVDLIVEVLRSLPLVQVDEKGEKVRPNQNRCIVIL 240
           SQMDSDQYVPITTVANLDHIKKLSTDVDLIVEVLRSLPLVQVDEKGEKVRPNQNRCIVIL
Sbjct: 181 SQMDSDQYVPITTVANLDHIKKLSTDVDLIVEVLRSLPLVQVDEKGEKVRPNQNRCIVIL 240

Query: 241 REISESTPVEEVEALFKGDNLPKFINCEFAYNDNWFITFETEADAQQAYKYLREEVKTFQ 300
           REISESTPVEEVEALFKGDNLPKFINCEFAYNDNWFITFETEADAQQAYKYLREEVKTFQ
Sbjct: 241 REISESTPVEEVEALFKGDNLPKFINCEFAYNDNWFITFETEADAQQAYKYLREEVKTFQ 300

Query: 301 GKPIKARIKAKAIAINTFLPKNGFRPLDVSLYAQQRYATSFYFPPMYSPQQQFPLYSLIT 360
           GKPIKARIKAKAIAINTFLPKNGFRPLDVSLYAQQRYATSFYFPPMYSPQQQFPLYSLIT
Sbjct: 301 GKPIKARIKAKAIAINTFLPKNGFRPLDVSLYAQQRYATSFYFPPMYSPQQQFPLYSLIT 360

Query: 361 PQTWSATHSYLDPPLVTPFPNTGFINGFTSPAFKPAASPLTSLRQYPPRSRNPSKSHLRH 420
           PQTWSATHSYLDPPLVTPFPNTGFINGFTSPAFKPAASPLTSLRQYPPRSRNPSKSHLRH
Sbjct: 361 PQTWSATHSYLDPPLVTPFPNTGFINGFTSPAFKPAASPLTSLRQYPPRSRNPSKSHLRH 420

Query: 421 AIPSAERGPGLLESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQNPSAYAKREAGPGRV 480
           AIPSAERGPGLLESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQNPSAYAKREAGPGRV
Sbjct: 421 AIPSAERGPGLLESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQNPSAYAKREAGPGRV 480

Query: 481 EPGSLESSPGLGRGRKNSFGYRKKREEKFTSSQTQSPTPPKPPSPSFELGLSSFPPLPGA 540
           EPGSLESSPGLGRGRKNSFGYRKKREEKFTSSQTQSPTPPKPPSPSFELGLSSFPPLPGA
Sbjct: 481 EPGSLESSPGLGRGRKNSFGYRKKREEKFTSSQTQSPTPPKPPSPSFELGLSSFPPLPGA 540

Query: 541 AGNLKTEDLFENRLSSLIIGPSKERTLSADASVNTLPVVVSREPSVPASCAVSATYERSP 600
           AGNLKTEDLFENRLSSLIIGPSKERTLSADASVNTLPVVVSREPSVPASCAVSATYERSP
Sbjct: 541 AGNLKTEDLFENRLSSLIIGPSKERTLSADASVNTLPVVVSREPSVPASCAVSATYERSP 600

Query: 601 SPAHLPDDPKVAEKQRETHSVDRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKE 660
           SPAHLPDDPKVAEKQRETHSVDRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKE
Sbjct: 601 SPAHLPDDPKVAEKQRETHSVDRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKE 660

Query: 661 PPSSPLQPQKEQKPNTVGCGKEEKKLAEPAERYREPPALKSTPGAPRDQRRPAGGRPSPS 720
           PPSSPLQPQKEQKPNTVGCGKEEKKLAEPAERYREPPALKSTPGAPRDQRRPAGGRPSPS
Sbjct: 661 PPSSPLQPQKEQKPNTVGCGKEEKKLAEPAERYREPPALKSTPGAPRDQRRPAGGRPSPS 720

Query: 721 AMGKRLSREQSTPPKSPQ 738
           AMGKRLSREQSTPPKSPQ
Sbjct: 721 AMGKRLSREQSTPPKSPQ 738


>gi|40353738 c-Mpl binding protein isoform a [Homo sapiens]
          Length = 724

 Score =  421 bits (1081), Expect = e-117
 Identities = 282/744 (37%), Positives = 404/744 (54%), Gaps = 83/744 (11%)

Query: 50  ATKVSELNPNAEVWG--APVLHLEASSAADGVSAAWEEVAGHHADRGPQGSDANGDGDQG 107
           A+K + LNPNA+VW   AP  + +A+    G  ++W E+A          ++ + D  + 
Sbjct: 9   ASKGTGLNPNAKVWQEIAPG-NTDATPVTHGTESSWHEIAATSGAHPEGNAELSEDICKE 67

Query: 108 HE---NAALPDPQESDPAD--MNALALGPSEYDSLPENSETGGNESQPDSQEDPREVLKK 162
           +E   +++    + +   +   + + LGP +     +  +  G  +   S ED +E LKK
Sbjct: 68  YEVMYSSSCETTRNTTGIEESTDGMILGPEDLSY--QIYDVSGESNSAVSTEDLKECLKK 125

Query: 163 TLEFCLSRENLASDMYLISQMDSDQYVPITTVANLDHIKKLSTDVDLIVEVLRSLPLVQV 222
            LEFC SRENL+ D+YLISQMDSDQ++PI TVAN++ IKKL+TD DLI+EVLRS P+VQV
Sbjct: 126 QLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILEVLRSSPMVQV 185

Query: 223 DEKGEKVRPNQNRCIVILREISESTPVEEVEALFKGDNLPKFINCEFAYNDNWFITFETE 282
           DEKGEKVRP+  RCIVILREI E+TP+EEV+ LFK +N PK I+CEFA+N NW+ITF+++
Sbjct: 186 DEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISCEFAHNSNWYITFQSD 245

Query: 283 ADAQQAYKYLREEVKTFQGKPIKARIKAKAIAINTFLPKNGFRPLDVSLYA-----QQRY 337
            DAQQA+KYLREEVKTFQGKPI  RIK    AINTF  KNG+R +D S+Y+     Q +Y
Sbjct: 246 TDAQQAFKYLREEVKTFQGKPIMVRIK----AINTFFAKNGYRLMDSSIYSHPIQTQAQY 301

Query: 338 ATSFYFPPMYSPQQQFPLYSLITPQTWSATHS-YLDPPLVTPFPNTGFINGFTSP-AFKP 395
           A+  +  P+Y+P QQ+ +YS++ PQ+WS   + Y + PL  PFPN  F+NGF SP ++K 
Sbjct: 302 ASPVFMQPVYNPHQQYSVYSIV-PQSWSPNPTPYFETPL-APFPNGSFVNGFNSPGSYKT 359

Query: 396 AASPLTSLRQYPPRSRNP---SKSHLRHAIP-SAERGPGLLESPSIFNFTADRLINGVRS 451
            A+ +   R +      P   S     H+   S   G G L   S  NF A+R      +
Sbjct: 360 NAAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDGQLNRYSSRNFPAER-----HN 414

Query: 452 PQTRQAGQTRTRIQNPSAYAKREAGPGRVEPGSLESSPGLGRGRKNSFGYRKKREEKFTS 511
           P T    Q +T +Q  ++  +            +E +   GRGR+  F  R++RE+   S
Sbjct: 415 P-TVTGHQEQTYLQKETSTLQ------------VEQNGDYGRGRRTLFRGRRRREDDRIS 461

Query: 512 SQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLKTEDLFENRLSSLIIGPSKER-----T 566
               S    K P+P F+L  S+FPPLPG++  +  E + ENR+S ++ G  KE+     T
Sbjct: 462 RPHPSTAESKAPTPKFDLLASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNEELT 521

Query: 567 LSADASVNTLPVVVSREP---SVPASCAVSAT-YERSPSPAHLPDDPKVAEKQRETHSVD 622
           +S     +      S +    S  + CA   T    +     L +D  V +      ++ 
Sbjct: 522 ISCPVPADEQTECTSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQTTIP 581

Query: 623 RLP-------SALTATACKSVQVNGAAT----ELRKPSYAEICQRTSKEPPSSPLQPQKE 671
             P        A TA+ C +  +N A      E RK SYAE+CQ+  KEP S  +QP +E
Sbjct: 582 VSPPSTTKPSRASTASPCNN-NINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPLRE 640

Query: 672 QKPNTVGCGKEEKKLA--EPAERYREPPALKST---------------PGAPRDQRRPAG 714
            + N V   K E   A     E+  E P  +++                G  R+QRR   
Sbjct: 641 LRSNVVSPTKNEDNGAPENSVEKPHEKPEARASKDYSGFRGNIIPRGAAGKIREQRRQFS 700

Query: 715 GRPSPSAMGKRLSREQSTPPKSPQ 738
            R  P  + +R  +EQ  PP+SP+
Sbjct: 701 HRAIPQGVTRRNGKEQYVPPRSPK 724


>gi|40353740 c-Mpl binding protein isoform b [Homo sapiens]
          Length = 730

 Score =  420 bits (1080), Expect = e-117
 Identities = 283/750 (37%), Positives = 399/750 (53%), Gaps = 89/750 (11%)

Query: 50  ATKVSELNPNAEVWG--APVLHLEASSAADGVSAAWEEVAGHHADRGPQGSDANGDGDQG 107
           A+K + LNPNA+VW   AP  + +A+    G  ++W E+A              G+ +  
Sbjct: 9   ASKGTGLNPNAKVWQEIAPG-NTDATPVTHGTESSWHEIAATSGAHPEVSVFNTGNAELS 67

Query: 108 HENAALPDPQESDPADM-----------NALALGPSEYDSLPENSETGGNESQPDSQEDP 156
            +     +   S   +            + + LGP +     +  +  G  +   S ED 
Sbjct: 68  EDICKEYEVMYSSSCETTRNTTGIEESTDGMILGPEDLSY--QIYDVSGESNSAVSTEDL 125

Query: 157 REVLKKTLEFCLSRENLASDMYLISQMDSDQYVPITTVANLDHIKKLSTDVDLIVEVLRS 216
           +E LKK LEFC SRENL+ D+YLISQMDSDQ++PI TVAN++ IKKL+TD DLI+EVLRS
Sbjct: 126 KECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILEVLRS 185

Query: 217 LPLVQVDEKGEKVRPNQNRCIVILREISESTPVEEVEALFKGDNLPKFINCEFAYNDNWF 276
            P+VQVDEKGEKVRP+  RCIVILREI E+TP+EEV+ LFK +N PK I+CEFA+N NW+
Sbjct: 186 SPMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISCEFAHNSNWY 245

Query: 277 ITFETEADAQQAYKYLREEVKTFQGKPIKARIKAKAIAINTFLPKNGFRPLDVSLYA--- 333
           ITF+++ DAQQA+KYLREEVKTFQGKPI ARIK    AINTF  KNG+R +D S+Y+   
Sbjct: 246 ITFQSDTDAQQAFKYLREEVKTFQGKPIMARIK----AINTFFAKNGYRLMDSSIYSHPI 301

Query: 334 --QQRYATSFYFPPMYSPQQQFPLYSLITPQTWSATHS-YLDPPLVTPFPNTGFINGFTS 390
             Q +YA+  +  P+Y+P QQ+ +YS++ PQ+WS   + Y + PL  PFPN  F+NGF S
Sbjct: 302 QTQAQYASPVFMQPVYNPHQQYSVYSIV-PQSWSPNPTPYFETPL-APFPNGSFVNGFNS 359

Query: 391 P-AFKPAASPLTSLRQYPPRSRNP---SKSHLRHAIP-SAERGPGLLESPSIFNFTADRL 445
           P ++K  A+ +   R +      P   S     H+   S   G G L   S  NF A+R 
Sbjct: 360 PGSYKTNAAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDGQLNRYSSRNFPAER- 418

Query: 446 INGVRSPQTRQAGQTRTRIQNPSAYAKREAGPGRVEPGSLESSPGLGRGRKNSFGYRKKR 505
                +P T    Q +T +Q  ++  +            +E +   GRGR+  F  R++R
Sbjct: 419 ----HNP-TVTGHQEQTYLQKETSTLQ------------VEQNGDYGRGRRTLFRGRRRR 461

Query: 506 EEKFTSSQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLKTEDLFENRLSSLIIGPSKER 565
           E+   S    S    K P+P F+L  S+FPPLPG++  +  E + ENR+S ++ G  KE+
Sbjct: 462 EDDRISRPHPSTAESKAPTPKFDLLASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEK 521

Query: 566 -----TLSADASVNTLPVVVSREP---SVPASCAVSAT-YERSPSPAHLPDDPKVAEKQR 616
                T+S     +      S +    S  + CA   T    +     L +D  V +   
Sbjct: 522 DNEELTISCPVPADEQTECTSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGL 581

Query: 617 ETHSVDRLP-------SALTATACKSVQVNGAAT----ELRKPSYAEICQRTSKEPPSSP 665
              ++   P        A TA+ C +  +N A      E RK SYAE+CQ+  KEP S  
Sbjct: 582 NQTTIPVSPPSTTKPSRASTASPCNN-NINAATAVALQEPRKLSYAEVCQKPPKEPSSVL 640

Query: 666 LQPQKEQKPNTVGCGKEEKKLA--EPAERYREPPALKST---------------PGAPRD 708
           +QP +E + N V   K E   A     E+  E P  +++                G  R+
Sbjct: 641 VQPLRELRSNVVSPTKNEDNGAPENSVEKPHEKPEARASKDYSGFRGNIIPRGAAGKIRE 700

Query: 709 QRRPAGGRPSPSAMGKRLSREQSTPPKSPQ 738
           QRR    R  P  + +R  +EQ  PP+SP+
Sbjct: 701 QRRQFSHRAIPQGVTRRNGKEQYVPPRSPK 730


>gi|40353736 c-Mpl binding protein isoform c [Homo sapiens]
          Length = 653

 Score =  253 bits (646), Expect = 4e-67
 Identities = 135/264 (51%), Positives = 183/264 (69%), Gaps = 10/264 (3%)

Query: 50  ATKVSELNPNAEVWG--APVLHLEASSAADGVSAAWEEVAGHHADRGPQGSDANGDGDQG 107
           A+K + LNPNA+VW   AP  + +A+    G  ++W E+A          ++ + D  + 
Sbjct: 9   ASKGTGLNPNAKVWQEIAPG-NTDATPVTHGTESSWHEIAATSGAHPEGNAELSEDICKE 67

Query: 108 HE---NAALPDPQESDPAD--MNALALGPSEYDSLPENSETGGNESQPDSQEDPREVLKK 162
           +E   +++    + +   +   + + LGP +     +  +  G  +   S ED +E LKK
Sbjct: 68  YEVMYSSSCETTRNTTGIEESTDGMILGPEDLSY--QIYDVSGESNSAVSTEDLKECLKK 125

Query: 163 TLEFCLSRENLASDMYLISQMDSDQYVPITTVANLDHIKKLSTDVDLIVEVLRSLPLVQV 222
            LEFC SRENL+ D+YLISQMDSDQ++PI TVAN++ IKKL+TD DLI+EVLRS P+VQV
Sbjct: 126 QLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILEVLRSSPMVQV 185

Query: 223 DEKGEKVRPNQNRCIVILREISESTPVEEVEALFKGDNLPKFINCEFAYNDNWFITFETE 282
           DEKGEKVRP+  RCIVILREI E+TP+EEV+ LFK +N PK I+CEFA+N NW+ITF+++
Sbjct: 186 DEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISCEFAHNSNWYITFQSD 245

Query: 283 ADAQQAYKYLREEVKTFQGKPIKA 306
            DAQQA+KYLREEVKTFQGKPI A
Sbjct: 246 TDAQQAFKYLREEVKTFQGKPIMA 269



 Score =  128 bits (322), Expect = 2e-29
 Identities = 117/409 (28%), Positives = 174/409 (42%), Gaps = 65/409 (15%)

Query: 374 PLVTPFPNTGFINGFTSP-AFKPAASPLTSLRQYPPRSRNP---SKSHLRHAIP-SAERG 428
           P++ PFPN  F+NGF SP ++K  A+ +   R +      P   S     H+   S   G
Sbjct: 266 PIMAPFPNGSFVNGFNSPGSYKTNAAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLG 325

Query: 429 PGLLESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQNPSAYAKREAGPGRVEPGSL--E 486
            G L   S  NF A+R                     NP+    +E    + E  +L  E
Sbjct: 326 DGQLNRYSSRNFPAER--------------------HNPTVTGHQEQTYLQKETSTLQVE 365

Query: 487 SSPGLGRGRKNSFGYRKKREEKFTSSQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLKT 546
            +   GRGR+  F  R++RE+   S    S    K P+P F+L  S+FPPLPG++  +  
Sbjct: 366 QNGDYGRGRRTLFRGRRRREDDRISRPHPSTAESKAPTPKFDLLASNFPPLPGSSSRMPG 425

Query: 547 EDLFENRLSSLIIGPSKER-----TLSADASVNTLPVVVSREP---SVPASCAVSAT-YE 597
           E + ENR+S ++ G  KE+     T+S     +      S +    S  + CA   T   
Sbjct: 426 ELVLENRMSDVVKGVYKEKDNEELTISCPVPADEQTECTSAQQLNMSTSSPCAAELTALS 485

Query: 598 RSPSPAHLPDDPKVAEKQRETHSVDRLP-------SALTATACKSVQVNGAAT----ELR 646
            +     L +D  V +      ++   P        A TA+ C +  +N A      E R
Sbjct: 486 TTQQEKDLIEDSSVQKDGLNQTTIPVSPPSTTKPSRASTASPCNN-NINAATAVALQEPR 544

Query: 647 KPSYAEICQRTSKEPPSSPLQPQKEQKPNTVGCGKEEKKLA--EPAERYREPPALKST-- 702
           K SYAE+CQ+  KEP S  +QP +E + N V   K E   A     E+  E P  +++  
Sbjct: 545 KLSYAEVCQKPPKEPSSVLVQPLRELRSNVVSPTKNEDNGAPENSVEKPHEKPEARASKD 604

Query: 703 -------------PGAPRDQRRPAGGRPSPSAMGKRLSREQSTPPKSPQ 738
                         G  R+QRR    R  P  + +R  +EQ  PP+SP+
Sbjct: 605 YSGFRGNIIPRGAAGKIREQRRQFSHRAIPQGVTRRNGKEQYVPPRSPK 653


>gi|61102725 la related protein isoform 2 [Homo sapiens]
          Length = 1096

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 27/74 (36%), Positives = 48/74 (64%), Gaps = 1/74 (1%)

Query: 153 QEDPREVLKKTLEFCLSRENLASDMYLISQMDSDQYVPITTVANLDHIKKLSTDVDLIVE 212
           QE  ++ +K+ +E+  S +NL  D +L  +MD+D ++PIT +A+   ++ L+TD+ LI  
Sbjct: 400 QELLKDYIKRQIEYYFSVDNLERDFFLRRKMDADGFLPITLIASFHRVQALTTDISLIFA 459

Query: 213 VLRSLPLVQ-VDEK 225
            L+   +V+ VDEK
Sbjct: 460 ALKDSKVVEIVDEK 473


>gi|39725634 la related protein isoform 1 [Homo sapiens]
          Length = 1019

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 27/74 (36%), Positives = 48/74 (64%), Gaps = 1/74 (1%)

Query: 153 QEDPREVLKKTLEFCLSRENLASDMYLISQMDSDQYVPITTVANLDHIKKLSTDVDLIVE 212
           QE  ++ +K+ +E+  S +NL  D +L  +MD+D ++PIT +A+   ++ L+TD+ LI  
Sbjct: 323 QELLKDYIKRQIEYYFSVDNLERDFFLRRKMDADGFLPITLIASFHRVQALTTDISLIFA 382

Query: 213 VLRSLPLVQ-VDEK 225
            L+   +V+ VDEK
Sbjct: 383 ALKDSKVVEIVDEK 396


>gi|30061565 La ribonucleoprotein domain family member 2 isoform 2
           [Homo sapiens]
          Length = 522

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 27/79 (34%), Positives = 50/79 (63%), Gaps = 2/79 (2%)

Query: 157 REVLKKTLEFCLSRENLASDMYLISQMDSDQYVPITTVANLDHIKKLSTDVDLIVEVLRS 216
           +E +K+ +E+  S ENL  D +L  +MD   ++PI+ +A    ++ L+T+++LI+E L+ 
Sbjct: 216 KEYIKRQIEYYFSVENLERDFFLRGKMDEQGFLPISLIAGFQRVQALTTNLNLILEALKD 275

Query: 217 LPLVQ-VDEK-GEKVRPNQ 233
              V+ VDEK  +K+ P +
Sbjct: 276 STEVEIVDEKMRKKIEPEK 294


>gi|30061569 La ribonucleoprotein domain family member 2 isoform 3
           [Homo sapiens]
          Length = 358

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 27/79 (34%), Positives = 50/79 (63%), Gaps = 2/79 (2%)

Query: 157 REVLKKTLEFCLSRENLASDMYLISQMDSDQYVPITTVANLDHIKKLSTDVDLIVEVLRS 216
           +E +K+ +E+  S ENL  D +L  +MD   ++PI+ +A    ++ L+T+++LI+E L+ 
Sbjct: 216 KEYIKRQIEYYFSVENLERDFFLRGKMDEQGFLPISLIAGFQRVQALTTNLNLILEALKD 275

Query: 217 LPLVQ-VDEK-GEKVRPNQ 233
              V+ VDEK  +K+ P +
Sbjct: 276 STEVEIVDEKMRKKIEPEK 294


>gi|30061567 La ribonucleoprotein domain family member 2 isoform 1
           [Homo sapiens]
          Length = 914

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 27/79 (34%), Positives = 50/79 (63%), Gaps = 2/79 (2%)

Query: 157 REVLKKTLEFCLSRENLASDMYLISQMDSDQYVPITTVANLDHIKKLSTDVDLIVEVLRS 216
           +E +K+ +E+  S ENL  D +L  +MD   ++PI+ +A    ++ L+T+++LI+E L+ 
Sbjct: 216 KEYIKRQIEYYFSVENLERDFFLRGKMDEQGFLPISLIAGFQRVQALTTNLNLILEALKD 275

Query: 217 LPLVQ-VDEK-GEKVRPNQ 233
              V+ VDEK  +K+ P +
Sbjct: 276 STEVEIVDEKMRKKIEPEK 294


>gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]
          Length = 1352

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 91/399 (22%), Positives = 149/399 (37%), Gaps = 56/399 (14%)

Query: 373  PPLVTPFPNTGFI------NGFTSPAFKPAASPLT--SLRQYPPRS--RNPSKSHLRHAI 422
            PPL  PF N   I      +   S   K   +P    SL + P  +  R+PS        
Sbjct: 977  PPLSGPFDNNNQIAYVDQSDSVDSSPVKEVKAPSHPGSLAKKPESTTKRSPSSKGTSEPE 1036

Query: 423  PSAERG-PGLLESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQNPSAYAKREAGPGRVE 481
             S  +G P L    S  + T+      V+   + +  ++R++  + S  + R + P   +
Sbjct: 1037 KSLRKGRPALASQESSLSSTSPSSPLPVKV--SLKPSRSRSKADSSSRGSGRHSSPAPAQ 1094

Query: 482  PGSLESSPGLGRGRKNSFGYRKKREEKFTSSQTQSPTPPKPPSPSFELGLSSFPPLPGAA 541
            P   ESSP      ++S      +++K  S+ T + +       S     S FPP     
Sbjct: 1095 PKK-ESSPK----SQDSVSSPSPQKQKSASALTYTASSTSAKKASGPATRSPFPP----- 1144

Query: 542  GNLKTEDLFENRLSSLIIGPSKERTLSADASVNTLPVVVSREPS-------VPASCAVSA 594
            G  +T D   +R  S     S   + ++ +  N+  V  +R          V +S   S 
Sbjct: 1145 GKSRTSDHSLSREGSRQSLGSDRASATSTSKPNSPRVSQARAGEGRGAGKHVRSSSMASL 1204

Query: 595  TYERSPSPAHLPDDPKVAEK----------QRETHSVDRLPSALTATACKSVQVNGAATE 644
                +   + L  D K  +K          Q+ET    R  + L  TA  S +  G++ +
Sbjct: 1205 RSPSTSIKSGLKRDSKSEDKGLSFFKSALRQKET----RRSTDLGKTALLSKKAGGSSVK 1260

Query: 645  LRKPSYAEICQRTSKEPPSSPLQPQKEQKPNTVGCGKEEKKLAEPAERYREPPALKSTPG 704
                    +C+ T  +      QP   Q+PN    GKE+    +PA       + + +  
Sbjct: 1261 -------SVCKNTGDDEAERGHQPPASQQPNANTTGKEQLVTKDPASAKHSLLSARKSKS 1313

Query: 705  APRDQRRPA--GGRPSPSAMGKRLSREQST---PPKSPQ 738
            +  D   P+  GGR S     K+LS    T   P + PQ
Sbjct: 1314 SQLDSGVPSSPGGRQSAEKSSKKLSSSMQTSARPSQKPQ 1352


>gi|109809739 La ribonucleoprotein domain family, member 7 [Homo
           sapiens]
          Length = 582

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 57/218 (26%), Positives = 91/218 (41%), Gaps = 61/218 (27%)

Query: 141 SETGGNES--QPDSQEDPREVLKKT--------------LEFCLSRENLASDMYLISQMD 184
           +E+G  E   + +S E  +EV KK               ++F     NL  D +L  Q++
Sbjct: 3   TESGNQEKVMEEESTEKKKEVEKKKRSRVKQVLADIAKQVDFWFGDANLHKDRFLREQIE 62

Query: 185 S--DQYVPITTVANLDHIKKLSTDVDLIVEVLRSLPLVQVDEKGEKVRPNQNRCIVILRE 242
              D YV I+ + + + +KKL+TD  LI   LRS  +V++D +G ++R          + 
Sbjct: 63  KSRDGYVDISLLVSFNKMKKLTTDGKLIARALRSSAVVELDLEGTRIRRK--------KP 114

Query: 243 ISESTPVEEVEALFKGDNLPKFINCEFA-----------------YNDNW------FITF 279
           + E  P +E E     + LPK +N  +                  Y          F+ F
Sbjct: 115 LGE-RPKDEDERTVYVELLPKNVNHSWIERVFGKCGNVVYISIPHYKSTGDPKGFAFVEF 173

Query: 280 ETEADAQQAYKYLR---EEV--------KTFQGKPIKA 306
           ET+  A +A ++L    EE         KT + KPI A
Sbjct: 174 ETKEQAAKAIEFLNNPPEEAPRKPGIFPKTVKNKPIPA 211


>gi|109809741 La ribonucleoprotein domain family, member 7 [Homo
           sapiens]
          Length = 582

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 57/218 (26%), Positives = 91/218 (41%), Gaps = 61/218 (27%)

Query: 141 SETGGNES--QPDSQEDPREVLKKT--------------LEFCLSRENLASDMYLISQMD 184
           +E+G  E   + +S E  +EV KK               ++F     NL  D +L  Q++
Sbjct: 3   TESGNQEKVMEEESTEKKKEVEKKKRSRVKQVLADIAKQVDFWFGDANLHKDRFLREQIE 62

Query: 185 S--DQYVPITTVANLDHIKKLSTDVDLIVEVLRSLPLVQVDEKGEKVRPNQNRCIVILRE 242
              D YV I+ + + + +KKL+TD  LI   LRS  +V++D +G ++R          + 
Sbjct: 63  KSRDGYVDISLLVSFNKMKKLTTDGKLIARALRSSAVVELDLEGTRIRRK--------KP 114

Query: 243 ISESTPVEEVEALFKGDNLPKFINCEFA-----------------YNDNW------FITF 279
           + E  P +E E     + LPK +N  +                  Y          F+ F
Sbjct: 115 LGE-RPKDEDERTVYVELLPKNVNHSWIERVFGKCGNVVYISIPHYKSTGDPKGFAFVEF 173

Query: 280 ETEADAQQAYKYLR---EEV--------KTFQGKPIKA 306
           ET+  A +A ++L    EE         KT + KPI A
Sbjct: 174 ETKEQAAKAIEFLNNPPEEAPRKPGIFPKTVKNKPIPA 211


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 75/338 (22%), Positives = 126/338 (37%), Gaps = 60/338 (17%)

Query: 409 RSRNPSKSHLRHAIPSAERGPGLLESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQNPS 468
           RS++P K       PS  R      + S     + R  +   S     + ++R+R  + S
Sbjct: 521 RSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYS 580

Query: 469 AYAKREAGPGRVEPGSLESSPGLGRGRKNSFGYRKKREEKFTSSQTQSPTPPKPPSPSFE 528
           +Y+ R +                   R +SF   + R   F+SS + SPT P P  PS  
Sbjct: 581 SYSSRSS-------------------RHSSFSGSRSRSRSFSSSPSPSPT-PSPHRPSIR 620

Query: 529 LGLSSFPPLPGAAGNLKTEDLFENRLSSLIIGPSKERTLSADASVNTLPVVVSREPSVPA 588
                 PP PG AG        E  +      P+  +     A+  T PV    +P  P 
Sbjct: 621 TKGEPAPP-PGKAG--------EKSVKKPAPPPAPPQ-----ATKTTAPVPEPTKPGDPR 666

Query: 589 SCAVSATYERSP--------SPAHLPDDPKVAEKQRETHSVDRLPSALTATACKSVQVNG 640
                    R+P        S +        +  +  + SV  + S  +AT+  S   + 
Sbjct: 667 EARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSV 726

Query: 641 AATELRKPSYAEICQRTSKEPPSSPLQPQKEQKPNTVGCGKEEKKLAEPAERYREPPALK 700
            + ++     + +   +S+ P  +P Q +KE+       GK +K+     E+ +      
Sbjct: 727 DSEDMYADLASPVSSASSRSP--APAQTRKEK-------GKSKKEDGVKEEKRKR----D 773

Query: 701 STPGAPRDQRRPAGGRPSPSAMGKRLSREQSTPPKSPQ 738
           S+   P+  + PAGG+ S     ++ S  Q  PP  PQ
Sbjct: 774 SSTQPPKSAKPPAGGKSS-----QQPSTPQQAPPGQPQ 806


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 89/385 (23%), Positives = 119/385 (30%), Gaps = 46/385 (11%)

Query: 373  PPLVTPFPNTGFINGFTSPAFKPAASPLTSLRQYPPRSRNPSKSHLRHAIPSAERGPGLL 432
            PP VTP           SP   PAA+P       PP +  PS      A P  +  P   
Sbjct: 1011 PPAVTP----------PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTP 1060

Query: 433  ES--PSIFNFTADRLINGVRSPQTRQAGQTRTRIQNPSAYAKREAGPGRVEP----GSLE 486
             +  PS     A   + G  +P        +     PS   K    P    P    G L 
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP--KGAPMPPAATPPSPKGGLA 1118

Query: 487  SSPGLGRGRKNSFGYRKKREEKFTSSQTQSPTPPKPPSPSFELGLSSFPPL--------- 537
            + P  G     +      +    T     +PT P    PS + GL++ PP          
Sbjct: 1119 TPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1178

Query: 538  -PGAAGNLKTEDLFENRLSSLIIGPSKERTLSADASVNTLPVVVSREPSVPASCAVSATY 596
             P   G L T        +     PS +  L+  +         +  PS     A  +  
Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1238

Query: 597  ERSPSPAHLPDDPKVAEKQRETHSVDRLPSALTATACKSVQVNGAATELRK--PSYAEIC 654
                +PA  P  PK              P+A T  + K     G AT   K  P+ A + 
Sbjct: 1239 GAPTTPAATPPSPKGGPATPPPKGAPTPPAA-TPPSLKG----GLATPPHKGAPNPAVVT 1293

Query: 655  QRTSK-----EPPSSPLQPQKEQKPNTVGCGKEEKKLAEPAERYREPPALKSTPGAPRDQ 709
              + K      PP     P     P+  G          P      PP+ K TP  P   
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353

Query: 710  RRPAGGRPSPSAMGKRLSREQSTPP 734
                GG  +PS      S+E  TPP
Sbjct: 1354 PSSKGGPTTPS------SKEGPTPP 1372



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 18/128 (14%)

Query: 24   SAHLMNGPISQTTSQTSSIPPLSQVPATKVSELNPNAEVWGAPVLHL--EASSAADGVSA 81
            +A    GP  QT   +++ PP+   P+ K     P + V  AP+L +  ++S  A G  A
Sbjct: 1697 TAPTRKGP--QTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDA 1754

Query: 82   AWEEVAGHHADRGPQG---SDANGDGDQGHENAALPDPQESD----PADMNALALGPSEY 134
            +       H+ +GP     S A+           LP P+ +     P+   +L L PS  
Sbjct: 1755 S-------HSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPV 1807

Query: 135  DSLPENSE 142
             +LP   +
Sbjct: 1808 PTLPPKQQ 1815



 Score = 30.0 bits (66), Expect = 8.1
 Identities = 103/425 (24%), Positives = 143/425 (33%), Gaps = 79/425 (18%)

Query: 344  PPMYSPQQQF-PLYSLI-TPQTWSATHSYLDPPLVTPFPNTGFINGFT-SPAFKPAASPL 400
            P   SPQ    PL +L+  P+   +  S   PP  TP P T  ++G + + A  P AS  
Sbjct: 709  PVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTP-PGTKKVDGISHTSALAPVAS-- 765

Query: 401  TSLRQYPPRSRNPSKSHLRHAIPSAERGP--GLLESPSIFNFTADRLINGVRSPQTRQAG 458
             S ++ P      S +       ++ +G    L +SPS    +         SPQT++  
Sbjct: 766  -SPKECPTEDSGASAT-------ASSKGTLTYLADSPSPLGVSV--------SPQTKRP- 808

Query: 459  QTRTRIQNPSAYAKREAGPGRVEPGSLESSPGLGRGRKNSFGYRKKREEKFTSSQTQSPT 518
             T+     P       + P  V P      P      +NS  ++  ++   T   T SPT
Sbjct: 809  PTKKGSAGPDTPIGNLSSP--VSPVEASFLP------ENSLSFQGSKDSPAT---THSPT 857

Query: 519  PPKP---PSPSFELGLS----SFPP----------LP-GAAGNLKTEDLFENRLSSLIIG 560
            PP P   P+PS    LS    + PP          LP    G           LS     
Sbjct: 858  PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSS 917

Query: 561  PSKERT------LSADASVNTLPVVVSREPSVPASCAVSATYERSPS-PAHLPDDPKVAE 613
            P K R       + A  S    P   +  P  P     + + + +P+ PA  P  PK   
Sbjct: 918  PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGP 977

Query: 614  KQRETHSVDRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKEPPSSPLQPQKEQK 673
                       P+A   +        G AT    PS        +  PPS    P     
Sbjct: 978  ATPSPKGAPTPPAATPPS-----PKGGPAT----PSPKGAPTPPAVTPPSPKGSPAATPF 1028

Query: 674  PNTVGCGKEEKKLAEPAERYREPPALKSTPGAPRDQR----RPAGGRPSPSAMGKRLSRE 729
            P     G      A P      P A     GAP         P GG  +PS  G   +  
Sbjct: 1029 PK----GASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP-TPP 1083

Query: 730  QSTPP 734
             +TPP
Sbjct: 1084 AATPP 1088


>gi|47933339 RNA binding motif protein 15 [Homo sapiens]
          Length = 977

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 42/139 (30%), Positives = 54/139 (38%), Gaps = 30/139 (21%)

Query: 408 PRSRNPSKSHLRHAIPSAERGPGLLESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQNP 467
           P S  P K   RH  PS +R P L  S   +N   DR               +R  ++ P
Sbjct: 657 PESDRPRK---RHCAPSPDRSPELSSSRDRYNSDNDR--------------SSRLLLERP 699

Query: 468 SAYAKREAGPGRVEPGSLESSPGLGRGRKNSFGYRKKREEKFTSSQTQSPTPPKPPSPSF 527
           S        P R   GSLE S G  R RKNS    + R+ +     T +PT  K P    
Sbjct: 700 S--------PIRDRRGSLEKSQGDKRDRKNSASAERDRKHR-----TTAPTEGKSPLKKE 746

Query: 528 ELGLSSFPPLPGAAGNLKT 546
           +    S P    A+  LK+
Sbjct: 747 DRSDGSAPSTSTASSKLKS 765


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 112/508 (22%), Positives = 180/508 (35%), Gaps = 80/508 (15%)

Query: 280  ETEADAQQAYKYLREEVK-----TFQGKPIKARIKAKAIAINTFLPKNGFRPLDVSLYAQ 334
            ++E  A Q   +L  E+K      F+  P      A ++ ++    +     ++V   A 
Sbjct: 1244 KSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMA- 1302

Query: 335  QRYATSFYFPPMYSPQQQFPLYSLITPQTWSATHSYLDPPLVTPFPNTGFINGFTSPAFK 394
                 S +  P +SP+ +    S +   ++ +   + +   +    NTGF +        
Sbjct: 1303 -----SSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNG 1357

Query: 395  P-----AASPLTSLRQYPPRSRNPSKSHLRHAIPSAERGPGLLESPSIFNFTADRL---- 445
            P        P   +++   RS   S S L    P A    G+  + SI +   D +    
Sbjct: 1358 PFLNQLETDPSLDMKEQSTRSSGHSSSELS---PDAVEKAGMSSNQSISSPVLDAVPRTP 1414

Query: 446  ----INGVRSPQTRQAGQTRT---RIQNPSAYAKREAGPGRVEPGSLE-SSPGL------ 491
                 +   SP+ +  G  RT   R ++ S+   R+ G G     SL  SSPG+      
Sbjct: 1415 SRERSSSASSPEMKD-GLPRTPSRRSRSGSSPGLRD-GSGTPSRHSLSGSSPGMKDIPRT 1472

Query: 492  -GRGRKNSFGYRKKREEKFTSSQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLKTED-- 548
              RGR           E     QT  P    P SP  EL      P    +G+  + D  
Sbjct: 1473 PSRGRSEC----DSSPEPKALPQTPRPRSRSPSSP--ELNNKCLTPQRERSGSESSVDQK 1526

Query: 549  ------LFENRLSS----LIIGPS------KERTLSADASVNTLPVVVSRE-----PSVP 587
                  L +   S     L + PS       E   S D+   T   +  R      P V 
Sbjct: 1527 TVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVD 1586

Query: 588  ASCAVSATYERSPSPAHLPDDPKVAEKQRETHSVDRLPSALTATACKSVQVNGAATELRK 647
            +   +S    RS S   + D P+ A + +        P A    A      +G++++ R 
Sbjct: 1587 SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRG 1646

Query: 648  PSYAEICQRTSKEPPSSPLQPQKEQKPNTVGCGKEEKKLAEPAERYREPPALKSTPGAPR 707
            PS        S    SSP  P K +        +  +   EP  + R PP  +S+  +P 
Sbjct: 1647 PS-----PEGSSSTESSPEHPPKSRTAR-----RGSRSSPEPKTKSRTPPRRRSSRSSPE 1696

Query: 708  DQRRPAGGRPSPSAMGKRLSREQSTPPK 735
              R+    R S SA     +R + TPP+
Sbjct: 1697 LTRKARLSRRSRSASSSPETRSR-TPPR 1723



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 89/394 (22%), Positives = 135/394 (34%), Gaps = 64/394 (16%)

Query: 359  ITPQTWSATHSYLDPPLVTPFPNTGFINGFTSPAFKPAASPLTSLRQYPPRSRNPSKSHL 418
            +TPQ  S   S  DP L +  P+    +G + P  K +  P    RQ P RS +P +  +
Sbjct: 865  VTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPP----RQSPSRSSSP-QPKV 919

Query: 419  RHAIPSAERGPGLLESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQNPSAYAKREAGPG 478
            +  I   +R      SPS              S  T +    R+R  +P +  +    P 
Sbjct: 920  KAIISPRQRSHSGSSSPS-------------PSRVTSRTTPRRSRSVSPCSNVESRLLPR 966

Query: 479  RVEPGSLESSPGLGRGRKNSFGYRKKREEKFTSSQTQSPTP-PKPPSPSFELGLSSFPPL 537
                GS  SSP            + K E     S + S +P PK  + +        PP 
Sbjct: 967  YSHSGS--SSPDT----------KVKPETPPRQSHSGSISPYPKVKAQT--------PPG 1006

Query: 538  PGAAGNLKTEDLFENRLSSLIIGPSKERTLSADASVNTLPVVVSREPSVPASCAVSATYE 597
            P  +G+ K+    E    SL+       +L A    +T P       S     ++    +
Sbjct: 1007 PSLSGS-KSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPP-----GESYFGVSSLQLKGQ 1060

Query: 598  RSPSPAHLPDDPKVAEKQRETHSVDRLPSALTATACKSVQVNGAATELRKPS-------- 649
               SP H  D      +Q  + S      + T+      + +   TEL   S        
Sbjct: 1061 SQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGE 1120

Query: 650  -YAEICQRTSKEPPSSPLQPQKEQKPNTVG---CGKEEKKLAEPAERYREPPALKSTPGA 705
              A    ++   P  S  Q      P        G+   + AE  E+   PP   +T   
Sbjct: 1121 FSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASP 1180

Query: 706  PRDQRR----PAGGRPSPSAMGKRLSREQSTPPK 735
            PR + +    P   RP  S + K   R   TPP+
Sbjct: 1181 PRQKDKFSPFPVQDRPESSLVFKDTLR---TPPR 1211



 Score = 37.0 bits (84), Expect = 0.066
 Identities = 75/357 (21%), Positives = 120/357 (33%), Gaps = 37/357 (10%)

Query: 404 RQYPPRSRNPSKSHLRHAIPSAERGPGLLESPSIFNFTADRLINGVRSPQTRQAGQTRT- 462
           R   P+S+  SK   R    S    P    +    +  +    +  RS     A +T T 
Sbjct: 230 RSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTT 289

Query: 463 ----RIQNPSAYAKREAGPGRVEPGSLE----SSPGLGRGRKNSFGYRKKREEKFTSSQT 514
               R  +P++  + E      EPG+      SSP     + +S    K +++K  S+  
Sbjct: 290 ALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATR 349

Query: 515 QSPTP------PKPPSPSFELGLSSFPPLPGAAGNLKTEDLFENRLSSLIIGPSKE---- 564
            SP+P      P+PP+P+         PL         + L    LS   + P  E    
Sbjct: 350 PSPSPERSSTGPEPPAPT---------PLLAERHGGSPQPLATTPLSQEPVNPPSEASPT 400

Query: 565 RTLSADASVNTLPVVVSREPSVPASCAVSATYERSPSPAHLPDDPKVAEKQRETHSVDRL 624
           R  S   S   LP   S E S P+      +   S S    P+ PK A        +   
Sbjct: 401 RDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSS----PESPKPAPAPGSHREISSS 456

Query: 625 PSALTATACKSVQVNGAATELRKPSYAEICQRTSKEPPSSPLQPQKEQKPNTVGCGKEEK 684
           P++   +  ++ +    +    +         T+K   S    P K     +        
Sbjct: 457 PTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRS 516

Query: 685 KLAEPAERYREP-----PALKSTPGAPRDQRRPAGGRPSPSAMGKRLSREQSTPPKS 736
           + A+   R R P           PG  R +     GR   +  G+  SR  +T  +S
Sbjct: 517 RSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRS 573



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 40/170 (23%), Positives = 62/170 (36%), Gaps = 22/170 (12%)

Query: 581  SREPSVPASCAV-------SATYERSPSPA------HLPDDPKVAEKQRETHSVDRLPSA 627
            S EP  PA  A+       S++  R PSP         P+ P  +   R        P  
Sbjct: 1621 SPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKT 1680

Query: 628  LTATACKSVQVNGAATELRKPSYAEICQRTSKEPPSSPLQPQKEQKPNTVGCGKEEKKLA 687
             + T  +      +    RK   +   +  S  P +    P + ++  +V          
Sbjct: 1681 KSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSS-------P 1733

Query: 688  EPAERYREPPALKSTPGAPRDQRRPAGGR-PSPSAMGKRLSREQSTPPKS 736
            EPAE+ R     +S   +PR +     GR PSP   G + SR +S   K+
Sbjct: 1734 EPAEKSRSSRRRRSA-SSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKT 1782


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 74/351 (21%), Positives = 122/351 (34%), Gaps = 23/351 (6%)

Query: 373 PPLVTPFPNTGFINGFTSPAFKPAASPLTSLRQYPPRSRNPSKSHLRHAIPSAERGPGLL 432
           P    P P T      T+P  KPA  P T     P   + P+ +  +   P+  + P   
Sbjct: 335 PTTKEPAPTTPKEPAPTAPK-KPA--PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 391

Query: 433 ESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQNPSAYAKREAGPGRVEPGSLESSPGLG 492
            + S    T +      +S  T     + T  + P+    +E  P      +    P   
Sbjct: 392 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP------TTPKKPAPT 445

Query: 493 RGRKNSFGYRKKREEKFTSSQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLKTEDLFEN 552
             ++ +      +E   T+++  +PT PK P+P+      + P  P        E L   
Sbjct: 446 TPKEPA--PTTPKEPAPTTTKKPAPTTPKEPAPTTPK--ETAPTTPKKLTPTTPEKLAPT 501

Query: 553 RLSSLIIGPSKERTLSADASVNTLPVVVSRE-PSVPASCAVSATYERSPSPAHLPDDPKV 611
                   P+    L+        P       P+ P + A +   E +P+    P  P  
Sbjct: 502 TPEKP--APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA-PTT 558

Query: 612 AEKQRETHSVDRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKEPPSSPLQPQKE 671
            ++   T   +  P+    TA  +++   A T  +KP+  E+   T+KEP S+       
Sbjct: 559 PKEPAPTTPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 617

Query: 672 QKPNTVGCGKEEKKLAEPAERYREPPALKSTPG-APRDQRRPAGGRPSPSA 721
             P     G       EPA    + PA  +  G AP   + PA   P   A
Sbjct: 618 TTPK----GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 664



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 75/361 (20%), Positives = 127/361 (35%), Gaps = 40/361 (11%)

Query: 397 ASPLTSLRQYPPRSRNPSKSHLRHAIPSAERGPGLLESPSIFNFTADRLINGVRSPQ-TR 455
           ++P T     P  ++ P+ +  +   P+  + P    + S      +      + P  T 
Sbjct: 254 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 313

Query: 456 QAGQTRTRIQNPSAYAKREAGPGRVEPG-SLESSPGLGRGRKNSFGYRKK------REEK 508
                 T  + P+    +E  P   EP  +    P     +K +    K+      +E  
Sbjct: 314 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 373

Query: 509 FTSSQTQSPTPPKPPSPSF--ELGLSSFPPLPGAAGNLKTEDLFENRLSSLIIGPSKERT 566
            T+++  SPT PK P+P+       ++  P P    +  T     +  ++    P+  + 
Sbjct: 374 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 433

Query: 567 LSADASVNTLPVVVSREPSVPASCAVSATYERSPSPAHLPDDPKVAEKQRETHSVDRLPS 626
            +        P    +EP+       + T  + P+P      PK         +    P 
Sbjct: 434 PAPTTPKKPAP-TTPKEPAPTTPKEPAPTTTKKPAPT----TPKEPAPTTPKETAPTTPK 488

Query: 627 ALTATACKSVQVNGAATELRKPSYA---EICQRTSKEP-PSSPLQP----QKEQKPNTVG 678
            LT T  + +    A T   KP+     E+   T +EP P++P +P     K   PNT  
Sbjct: 489 KLTPTTPEKL----APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP- 543

Query: 679 CGKEEKKLAEPAERYREPPALKSTP--GAPRDQRRPAGGRPSPSAMGKRLSREQSTPPKS 736
                    EPA    + PA  +TP   AP   +  A   P  +A    L     T PK 
Sbjct: 544 --------KEPAPTTPKEPA-PTTPKEPAPTTPKETAPTTPKGTA-PTTLKEPAPTTPKK 593

Query: 737 P 737
           P
Sbjct: 594 P 594


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 74/351 (21%), Positives = 122/351 (34%), Gaps = 23/351 (6%)

Query: 373 PPLVTPFPNTGFINGFTSPAFKPAASPLTSLRQYPPRSRNPSKSHLRHAIPSAERGPGLL 432
           P    P P T      T+P  KPA  P T     P   + P+ +  +   P+  + P   
Sbjct: 376 PTTKEPAPTTPKEPAPTAPK-KPA--PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 432

Query: 433 ESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQNPSAYAKREAGPGRVEPGSLESSPGLG 492
            + S    T +      +S  T     + T  + P+    +E  P      +    P   
Sbjct: 433 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP------TTPKKPAPT 486

Query: 493 RGRKNSFGYRKKREEKFTSSQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLKTEDLFEN 552
             ++ +      +E   T+++  +PT PK P+P+      + P  P        E L   
Sbjct: 487 TPKEPA--PTTPKEPAPTTTKKPAPTTPKEPAPTTPK--ETAPTTPKKLTPTTPEKLAPT 542

Query: 553 RLSSLIIGPSKERTLSADASVNTLPVVVSRE-PSVPASCAVSATYERSPSPAHLPDDPKV 611
                   P+    L+        P       P+ P + A +   E +P+    P  P  
Sbjct: 543 TPEKP--APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA-PTT 599

Query: 612 AEKQRETHSVDRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKEPPSSPLQPQKE 671
            ++   T   +  P+    TA  +++   A T  +KP+  E+   T+KEP S+       
Sbjct: 600 PKEPAPTTPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 658

Query: 672 QKPNTVGCGKEEKKLAEPAERYREPPALKSTPG-APRDQRRPAGGRPSPSA 721
             P     G       EPA    + PA  +  G AP   + PA   P   A
Sbjct: 659 TTPK----GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 705



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 75/361 (20%), Positives = 127/361 (35%), Gaps = 40/361 (11%)

Query: 397 ASPLTSLRQYPPRSRNPSKSHLRHAIPSAERGPGLLESPSIFNFTADRLINGVRSPQ-TR 455
           ++P T     P  ++ P+ +  +   P+  + P    + S      +      + P  T 
Sbjct: 295 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 354

Query: 456 QAGQTRTRIQNPSAYAKREAGPGRVEPG-SLESSPGLGRGRKNSFGYRKK------REEK 508
                 T  + P+    +E  P   EP  +    P     +K +    K+      +E  
Sbjct: 355 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 414

Query: 509 FTSSQTQSPTPPKPPSPSF--ELGLSSFPPLPGAAGNLKTEDLFENRLSSLIIGPSKERT 566
            T+++  SPT PK P+P+       ++  P P    +  T     +  ++    P+  + 
Sbjct: 415 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 474

Query: 567 LSADASVNTLPVVVSREPSVPASCAVSATYERSPSPAHLPDDPKVAEKQRETHSVDRLPS 626
            +        P    +EP+       + T  + P+P      PK         +    P 
Sbjct: 475 PAPTTPKKPAP-TTPKEPAPTTPKEPAPTTTKKPAPT----TPKEPAPTTPKETAPTTPK 529

Query: 627 ALTATACKSVQVNGAATELRKPSYA---EICQRTSKEP-PSSPLQP----QKEQKPNTVG 678
            LT T  + +    A T   KP+     E+   T +EP P++P +P     K   PNT  
Sbjct: 530 KLTPTTPEKL----APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP- 584

Query: 679 CGKEEKKLAEPAERYREPPALKSTP--GAPRDQRRPAGGRPSPSAMGKRLSREQSTPPKS 736
                    EPA    + PA  +TP   AP   +  A   P  +A    L     T PK 
Sbjct: 585 --------KEPAPTTPKEPA-PTTPKEPAPTTPKETAPTTPKGTA-PTTLKEPAPTTPKK 634

Query: 737 P 737
           P
Sbjct: 635 P 635


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 74/351 (21%), Positives = 122/351 (34%), Gaps = 23/351 (6%)

Query: 373 PPLVTPFPNTGFINGFTSPAFKPAASPLTSLRQYPPRSRNPSKSHLRHAIPSAERGPGLL 432
           P    P P T      T+P  KPA  P T     P   + P+ +  +   P+  + P   
Sbjct: 428 PTTKEPAPTTPKEPAPTAPK-KPA--PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 484

Query: 433 ESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQNPSAYAKREAGPGRVEPGSLESSPGLG 492
            + S    T +      +S  T     + T  + P+    +E  P      +    P   
Sbjct: 485 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP------TTPKKPAPT 538

Query: 493 RGRKNSFGYRKKREEKFTSSQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLKTEDLFEN 552
             ++ +      +E   T+++  +PT PK P+P+      + P  P        E L   
Sbjct: 539 TPKEPA--PTTPKEPAPTTTKKPAPTTPKEPAPTTPK--ETAPTTPKKLTPTTPEKLAPT 594

Query: 553 RLSSLIIGPSKERTLSADASVNTLPVVVSRE-PSVPASCAVSATYERSPSPAHLPDDPKV 611
                   P+    L+        P       P+ P + A +   E +P+    P  P  
Sbjct: 595 TPEKP--APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA-PTT 651

Query: 612 AEKQRETHSVDRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKEPPSSPLQPQKE 671
            ++   T   +  P+    TA  +++   A T  +KP+  E+   T+KEP S+       
Sbjct: 652 PKEPAPTTPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 710

Query: 672 QKPNTVGCGKEEKKLAEPAERYREPPALKSTPG-APRDQRRPAGGRPSPSA 721
             P     G       EPA    + PA  +  G AP   + PA   P   A
Sbjct: 711 TTPK----GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 757



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 75/361 (20%), Positives = 127/361 (35%), Gaps = 40/361 (11%)

Query: 397 ASPLTSLRQYPPRSRNPSKSHLRHAIPSAERGPGLLESPSIFNFTADRLINGVRSPQ-TR 455
           ++P T     P  ++ P+ +  +   P+  + P    + S      +      + P  T 
Sbjct: 347 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 406

Query: 456 QAGQTRTRIQNPSAYAKREAGPGRVEPG-SLESSPGLGRGRKNSFGYRKK------REEK 508
                 T  + P+    +E  P   EP  +    P     +K +    K+      +E  
Sbjct: 407 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 466

Query: 509 FTSSQTQSPTPPKPPSPSF--ELGLSSFPPLPGAAGNLKTEDLFENRLSSLIIGPSKERT 566
            T+++  SPT PK P+P+       ++  P P    +  T     +  ++    P+  + 
Sbjct: 467 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 526

Query: 567 LSADASVNTLPVVVSREPSVPASCAVSATYERSPSPAHLPDDPKVAEKQRETHSVDRLPS 626
            +        P    +EP+       + T  + P+P      PK         +    P 
Sbjct: 527 PAPTTPKKPAP-TTPKEPAPTTPKEPAPTTTKKPAPT----TPKEPAPTTPKETAPTTPK 581

Query: 627 ALTATACKSVQVNGAATELRKPSYA---EICQRTSKEP-PSSPLQP----QKEQKPNTVG 678
            LT T  + +    A T   KP+     E+   T +EP P++P +P     K   PNT  
Sbjct: 582 KLTPTTPEKL----APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP- 636

Query: 679 CGKEEKKLAEPAERYREPPALKSTP--GAPRDQRRPAGGRPSPSAMGKRLSREQSTPPKS 736
                    EPA    + PA  +TP   AP   +  A   P  +A    L     T PK 
Sbjct: 637 --------KEPAPTTPKEPA-PTTPKEPAPTTPKETAPTTPKGTA-PTTLKEPAPTTPKK 686

Query: 737 P 737
           P
Sbjct: 687 P 687


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 74/351 (21%), Positives = 122/351 (34%), Gaps = 23/351 (6%)

Query: 373 PPLVTPFPNTGFINGFTSPAFKPAASPLTSLRQYPPRSRNPSKSHLRHAIPSAERGPGLL 432
           P    P P T      T+P  KPA  P T     P   + P+ +  +   P+  + P   
Sbjct: 469 PTTKEPAPTTPKEPAPTAPK-KPA--PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 525

Query: 433 ESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQNPSAYAKREAGPGRVEPGSLESSPGLG 492
            + S    T +      +S  T     + T  + P+    +E  P      +    P   
Sbjct: 526 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP------TTPKKPAPT 579

Query: 493 RGRKNSFGYRKKREEKFTSSQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLKTEDLFEN 552
             ++ +      +E   T+++  +PT PK P+P+      + P  P        E L   
Sbjct: 580 TPKEPA--PTTPKEPAPTTTKKPAPTTPKEPAPTTPK--ETAPTTPKKLTPTTPEKLAPT 635

Query: 553 RLSSLIIGPSKERTLSADASVNTLPVVVSRE-PSVPASCAVSATYERSPSPAHLPDDPKV 611
                   P+    L+        P       P+ P + A +   E +P+    P  P  
Sbjct: 636 TPEKP--APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA-PTT 692

Query: 612 AEKQRETHSVDRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKEPPSSPLQPQKE 671
            ++   T   +  P+    TA  +++   A T  +KP+  E+   T+KEP S+       
Sbjct: 693 PKEPAPTTPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 751

Query: 672 QKPNTVGCGKEEKKLAEPAERYREPPALKSTPG-APRDQRRPAGGRPSPSA 721
             P     G       EPA    + PA  +  G AP   + PA   P   A
Sbjct: 752 TTPK----GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 798



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 75/361 (20%), Positives = 127/361 (35%), Gaps = 40/361 (11%)

Query: 397 ASPLTSLRQYPPRSRNPSKSHLRHAIPSAERGPGLLESPSIFNFTADRLINGVRSPQ-TR 455
           ++P T     P  ++ P+ +  +   P+  + P    + S      +      + P  T 
Sbjct: 388 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 447

Query: 456 QAGQTRTRIQNPSAYAKREAGPGRVEPG-SLESSPGLGRGRKNSFGYRKK------REEK 508
                 T  + P+    +E  P   EP  +    P     +K +    K+      +E  
Sbjct: 448 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 507

Query: 509 FTSSQTQSPTPPKPPSPSF--ELGLSSFPPLPGAAGNLKTEDLFENRLSSLIIGPSKERT 566
            T+++  SPT PK P+P+       ++  P P    +  T     +  ++    P+  + 
Sbjct: 508 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 567

Query: 567 LSADASVNTLPVVVSREPSVPASCAVSATYERSPSPAHLPDDPKVAEKQRETHSVDRLPS 626
            +        P    +EP+       + T  + P+P      PK         +    P 
Sbjct: 568 PAPTTPKKPAP-TTPKEPAPTTPKEPAPTTTKKPAPT----TPKEPAPTTPKETAPTTPK 622

Query: 627 ALTATACKSVQVNGAATELRKPSYA---EICQRTSKEP-PSSPLQP----QKEQKPNTVG 678
            LT T  + +    A T   KP+     E+   T +EP P++P +P     K   PNT  
Sbjct: 623 KLTPTTPEKL----APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP- 677

Query: 679 CGKEEKKLAEPAERYREPPALKSTP--GAPRDQRRPAGGRPSPSAMGKRLSREQSTPPKS 736
                    EPA    + PA  +TP   AP   +  A   P  +A    L     T PK 
Sbjct: 678 --------KEPAPTTPKEPA-PTTPKEPAPTTPKETAPTTPKGTA-PTTLKEPAPTTPKK 727

Query: 737 P 737
           P
Sbjct: 728 P 728


>gi|193083183 synaptopodin 2 isoform a [Homo sapiens]
          Length = 1261

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 86/388 (22%), Positives = 128/388 (32%), Gaps = 53/388 (13%)

Query: 373  PPLVTPFPNTGFINGFTSPAFKPAASPLTSLRQYPP-RSRNPSKSHLRHAIPSAERGPGL 431
            PP V P P     +        P  SP  +  Q P   + NPSK  +  +I  A+     
Sbjct: 756  PPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPP 815

Query: 432  LESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQNPSAYAKREAGPGRVEPGSLESSPGL 491
                S  N          + PQ   A Q  T     S        PG V P +    PG+
Sbjct: 816  ARPASTLNVAGP-----FKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSN--ELPGM 868

Query: 492  GRGRKNSFGYRKKREEKFT---------SSQTQSPTPPKPPSPSFELGLSSFPPLPGAAG 542
                   F  R+ R EK+          +++ QSPTP  P S  +   + + PP+     
Sbjct: 869  SGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPI 928

Query: 543  NLKTEDLFENRLSSLIIGPSKERTLSADASVNTLPVVVSREPSVPASCAVSATYERSPSP 602
            +  +  L   +       PSK         +N L V+  +   + AS     T++   + 
Sbjct: 929  HSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASL---FTFQPPDAK 985

Query: 603  AHLPDDPKVAEKQRETHSVDRLPSALTATACKSVQ---VNGAATELRKPS-YAEICQRTS 658
              LP    V             P  + A +  +VQ   V         PS +AE     S
Sbjct: 986  DGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVS 1045

Query: 659  KEP-----PSSPLQ------------PQKEQKPNTVGCGKEEKKLAEPAERYREPPALKS 701
              P     P+SP Q            P+   K + V   +  + L+ P      PP + +
Sbjct: 1046 ASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSGVTIQESGRSLSLPGRSV--PPPIST 1103

Query: 702  TP----------GAPRDQRRPAGGRPSP 719
            +P            P D    A  RP+P
Sbjct: 1104 SPWVYQPTYSYSSKPTDGLEKANKRPTP 1131



 Score = 30.4 bits (67), Expect = 6.2
 Identities = 57/262 (21%), Positives = 94/262 (35%), Gaps = 44/262 (16%)

Query: 451 SPQTRQAGQTRTRIQNPSAYAKREAGPGR----VEPGSLESSPGLGR-GRKNSFGYRKK- 504
           +P   Q       ++  ++Y ++E    R    V    +E S GLG   ++N F    + 
Sbjct: 517 TPSREQDAAQTDGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSET 576

Query: 505 ----------REEKFTSSQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLKTEDLFENRL 554
                     R  K        P  P  P+ +    ++ FP  P  +      D F   +
Sbjct: 577 ANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGV 636

Query: 555 SSLIIGPS------KERTLSADASVNTLPVVVSREP--SVPA---SCAVSATYERSPSPA 603
           SS I GP+      +    S  A  ++   + SR+   SVPA        A    +  P 
Sbjct: 637 SSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPM 696

Query: 604 HLPDDPKV------------AEKQRETHS-VDRLPS----ALTATACKSVQVNGAATELR 646
               +PKV            +E +R T +  D  P     +L A AC  +Q + A  +  
Sbjct: 697 FTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTP 756

Query: 647 KPSYAEICQRTSKEPPSSPLQP 668
            P   +   ++S   P +P+ P
Sbjct: 757 PPVAPKPAVKSSSSQPVTPVSP 778


>gi|153792780 additional sex combs like 2 [Homo sapiens]
          Length = 1435

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 46/176 (26%), Positives = 66/176 (37%), Gaps = 25/176 (14%)

Query: 506 EEKFTSSQTQ---------SPTPPKPPSPSFELGLSSFPPLPGAAGNLKTEDLFENRLSS 556
           E K T SQ Q           TPP PP+P+   G  +  P P     L  E L   R ++
Sbjct: 755 ETKTTPSQAQPHSVSGAQLQQTPPVPPTPAVS-GACTSVPSPAHIEKLDNEKLNPTRATA 813

Query: 557 LII------GPSKERTLSADASVNTLPVVVSREPSVPASCAVSATYERSPSPAHLPDDPK 610
            +       GPS  R   A +   T P ++S   + P  CA   T E    P+    +P 
Sbjct: 814 TVASVSHPQGPSSCRQEKAPSP--TGPALIS--GASPVHCAADGTVELKAGPSKNIPNPS 869

Query: 611 VAEKQRETHSVDRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKEPPSSPL 666
            + K   +     +P A+T +   S+       +L  P  +         PPSS L
Sbjct: 870 ASSKTDAS-----VPVAVTPSPLTSLLTTATLEKLPVPQVSATTAPAGSAPPSSTL 920


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 86/374 (22%), Positives = 123/374 (32%), Gaps = 77/374 (20%)

Query: 373 PPLVTPFPNTGFINGFTSPAFKPAASPLTSLRQYPPRSRNPSKSHLRHAIPSAERGPGLL 432
           PPL TP P         SP+  P+   L S    PP    PS +      P  +  P L 
Sbjct: 335 PPLATPLPLAP-----PSPSAPPSLQTLPSPPATPPSQAPPSMT-----TPPMQAPPSLQ 384

Query: 433 ESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQNPSAYAKREAGPGRVEPGSLESSPGLG 492
             P I                     Q    + +PS     +A P  +   SL+++  LG
Sbjct: 385 TIPPI---------------------QVPHSLTSPSL----QAPPSPLALSSLQATTSLG 419

Query: 493 RGR---KNSFGYRKKREEK--FTSSQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLKTE 547
                  +SF     R+ +   TS    + TPP  P     L L + PPL          
Sbjct: 420 SPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL---------- 469

Query: 548 DLFENRLSSLIIGPSKERTLSADASVNTLPVVVSREPSVPASCAVSATYERSPSPAHLPD 607
              +  LS  +   S   T+     +  L  + S  P  P S  +    E   S A  P 
Sbjct: 470 ---QTSLSPAVSPLSSPLTIH---PLQALSSLASHSPQAPLSSLIMPPLETQSSLA--PP 521

Query: 608 DPKVAEKQRETHSVDRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKEPPSSPLQ 667
             +       T  ++ LPS L     ++         L  P     C     + P SPL 
Sbjct: 522 SLQTPPASLTTPPLENLPS-LAPPPLQTASAPLTTPHLETPPCPAPC---PLQAPPSPLT 577

Query: 668 PQKEQKPNTVGCGKEEKKLAEPAERYREPPALKSTP--GAPRDQRRPAGGRP--SPSAMG 723
               + P+++         A P    + PPAL S P  G P     P    P  +P  + 
Sbjct: 578 TPPPETPSSI---------ATPPP--QAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA 626

Query: 724 KRLSREQSTPPKSP 737
               +   +PP SP
Sbjct: 627 LPPLQAPPSPPASP 640



 Score = 37.4 bits (85), Expect = 0.050
 Identities = 91/401 (22%), Positives = 126/401 (31%), Gaps = 58/401 (14%)

Query: 344 PPMYSP-QQQFPLYSLITPQTWSATHSYLDPPLVTPFPNTGFINGFTSPAFKPAASPLTS 402
           PP  +P   Q P   L TP   + +     PP   P   +  + G  SP   P A+P   
Sbjct: 561 PPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPP- 619

Query: 403 LRQYPPRSRNPSKSHLRHAIPSAERGPGLLESPSIFNFTADRLINGVRSPQTRQAGQT-- 460
             Q PP    P          S    P    SP   N  A  L+    SP      Q   
Sbjct: 620 --QAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677

Query: 461 ---RTRIQNPSAYAKREAGPGRVEPGSLESSPGLGRGRKNSFGYRKKREEKFTSSQTQSP 517
               +   +PSA    +A P    P  L+  P                    +   + S 
Sbjct: 678 SPPASPPVSPSATPPSQAPPSLAAP-PLQVPP----------------SPPASPPMSPSA 720

Query: 518 TPPKPPSPSFELGLSSFPPLPGAAGNLKTEDLFENRLSSLIIGPSKERTLSADASVNTLP 577
           TPP    P         PP P A+  +        R+  L+  P  +   S  AS+   P
Sbjct: 721 TPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780

Query: 578 VVVSREPSVPASCAVSATYERSPSPAHLPDDPKVAEKQRETHSVDRLPSALTATACKSVQ 637
            +    P  P + A       +P    LP  P     Q        LP +  AT      
Sbjct: 781 -LAKPPPQAPPALA-------TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 832

Query: 638 VNGAATELRKPSYAEICQRTSKEPPSSPLQPQKEQKPNTVGCGKEEKKLAEPAERYREPP 697
              AA  L+ P            PP+SP   Q  ++P T G    +  ++ P        
Sbjct: 833 PVLAAPLLQVP----------PSPPASPTL-QAPRRPPTPG---PDTSVSGPR------L 872

Query: 698 ALKSTPGAPRDQRRPAGGRPSPSAMGKRLSREQSTPPKSPQ 738
            L   PG P     P    PS +  G  L+   S+   +P+
Sbjct: 873 TLALAPGPP----PPPSRSPSSTLSGPDLAGHSSSATSTPE 909



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 87/367 (23%), Positives = 110/367 (29%), Gaps = 79/367 (21%)

Query: 383 GFINGFTSPAFKPAASPLTSL--RQYPPRSRNPSKSHLRHAIPSAERGPGLLESPSIFNF 440
           G I G T P   P A P  S       P SR P+      A P+    PG + SP     
Sbjct: 63  GGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP----- 117

Query: 441 TADRLINGVRSPQTRQA--GQTRTRIQNPSAYAKREAGPGRVEPGSLESSPGLGRGRKNS 498
                  G  S  TR    GQ   RI      A+     G+       S+   G  R   
Sbjct: 118 -------GRASGTTRPGPLGQKGLRIS-----AEETVARGKATEAPKRSALSAGARR--- 162

Query: 499 FGYRKKREEKFTSSQTQSPTPPKPPSPSF---------ELGLSSFPPLPGAAGNLKTEDL 549
                          T  PT P  PSP+          E+GL    P P A     TE  
Sbjct: 163 --------------DTSGPT-PGTPSPAMARRSRAAGTEVGLPR--PAPSARPRPPTE-- 203

Query: 550 FENRLSSLIIGPSKERTLSADASVNTLPVVVSREPSVPASCAVSATYERSPSPAHLPDDP 609
                     GP K  + +++ S         R PS        A+   S S   L    
Sbjct: 204 ----------GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253

Query: 610 KVAEKQRETHSVDRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKEPPSSPLQPQ 669
           +     R T    R P+  +    K +Q       LR P       R    P   PL   
Sbjct: 254 RSGPSARGT---PRAPAHPSQPKPKGLQA------LRPPQVTP--PRKDAAPALGPLSSS 302

Query: 670 KEQKPNTVGCGKEEKKLAEPAERYREPPALKSTPGAPRDQRRPAGGRPSPSAMG--KRLS 727
               P+  G    + +   P +    P      P  P     P    PSPSA    + L 
Sbjct: 303 PLATPSPSG---TKARPVPPPDNAATPLPATLPPSPPLATPLPL-APPSPSAPPSLQTLP 358

Query: 728 REQSTPP 734
              +TPP
Sbjct: 359 SPPATPP 365



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 62/284 (21%), Positives = 93/284 (32%), Gaps = 37/284 (13%)

Query: 399 PLTSLRQYPPRS--RNPSKSHLRHAI----PSAERGP---GLLESPSI--FNFTADRLIN 447
           P  S R  PP    R    S   H+     P+A R P   G L+ P+    + +A  L +
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251

Query: 448 GVRS-PQTRQAGQTRTRIQNPSAYAKREAGPGRVEPGSLESSPGLGRGRKNSFGYRKKRE 506
             RS P  R   +       P     +   P +V P   +++P LG    +         
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSG 311

Query: 507 EKFTS----SQTQSPTPPK-PPSPSFELGLSSFPPLPGAAGNLKTEDLFENRLSSLIIGP 561
            K           +P P   PPSP     L   PP P A  +L+T           +  P
Sbjct: 312 TKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQT-----------LPSP 360

Query: 562 SKERTLSADASVNTLPVVVSREPSVPASCAVSATYERSPSPAHLPDDPKVAEKQRETHSV 621
                  A  S+ T P  +   PS+     +   +  +      P  P      + T S+
Sbjct: 361 PATPPSQAPPSMTTPP--MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418

Query: 622 DRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKEPPSSP 665
              P+     +  ++        L  PS      R +  PP SP
Sbjct: 419 GS-PTLQATHSFLTMSPRQTQASLTSPS------RPASTPPDSP 455


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 78/347 (22%), Positives = 122/347 (35%), Gaps = 32/347 (9%)

Query: 374  PLVTPFPNTGFINGFTSPAFKPAASPLTSLRQYP--PRSRNPSKSHLRHAIPSAERG--P 429
            PL  P        G  S  F P +     L Q P  PR+ +P    + H++     G  P
Sbjct: 669  PLSLPVNRMQVSQGMNS--FNPMSLGNVQLPQAPMGPRAASP----MNHSVQMNSMGSVP 722

Query: 430  GLLESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQN--PSAYAKREAGPGRVEPGSLES 487
            G+  SPS      + +     +   +   Q++   QN  PS+      G G+  P     
Sbjct: 723  GMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQ-PPAQTGV 781

Query: 488  SPGL--GRGRKNSFGYRKKREEKFTSSQ-TQSPTPPKPPSPSFELGLSSF---------P 535
            S G   G    N       +  +      TQSP  P PP  S   G+ S          P
Sbjct: 782  SQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTP 841

Query: 536  PLPGAAGNLKTEDLFENRLSSLIIG--PSKERTLSADASVNTLPVVVSREPSVPA---SC 590
            P P A     T      +  +   G  PS  +T S           V+ +P  P    S 
Sbjct: 842  PQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSV 901

Query: 591  AVSATYERSPSPAHLPDDPKVAEKQRETHSVDRLPS-ALTATACKSVQVNGAATELRKPS 649
            A   + ++ P+P H    P     Q      +R+P+ +  A+A  + Q  G    + +  
Sbjct: 902  ATPQSSQQQPTPVH-AQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMK 960

Query: 650  YAEICQRTSKEPPSSPLQPQKEQKPNTVGCGKEEKKLAEPAERYREP 696
                 + T  +P  S  +P+ E     +    + K+  + AE+  EP
Sbjct: 961  TETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEP 1007


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 78/347 (22%), Positives = 122/347 (35%), Gaps = 32/347 (9%)

Query: 374  PLVTPFPNTGFINGFTSPAFKPAASPLTSLRQYP--PRSRNPSKSHLRHAIPSAERG--P 429
            PL  P        G  S  F P +     L Q P  PR+ +P    + H++     G  P
Sbjct: 707  PLSLPVNRMQVSQGMNS--FNPMSLGNVQLPQAPMGPRAASP----MNHSVQMNSMGSVP 760

Query: 430  GLLESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQN--PSAYAKREAGPGRVEPGSLES 487
            G+  SPS      + +     +   +   Q++   QN  PS+      G G+  P     
Sbjct: 761  GMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQ-PPAQTGV 819

Query: 488  SPGL--GRGRKNSFGYRKKREEKFTSSQ-TQSPTPPKPPSPSFELGLSSF---------P 535
            S G   G    N       +  +      TQSP  P PP  S   G+ S          P
Sbjct: 820  SQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTP 879

Query: 536  PLPGAAGNLKTEDLFENRLSSLIIG--PSKERTLSADASVNTLPVVVSREPSVPA---SC 590
            P P A     T      +  +   G  PS  +T S           V+ +P  P    S 
Sbjct: 880  PQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSV 939

Query: 591  AVSATYERSPSPAHLPDDPKVAEKQRETHSVDRLPS-ALTATACKSVQVNGAATELRKPS 649
            A   + ++ P+P H    P     Q      +R+P+ +  A+A  + Q  G    + +  
Sbjct: 940  ATPQSSQQQPTPVH-AQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMK 998

Query: 650  YAEICQRTSKEPPSSPLQPQKEQKPNTVGCGKEEKKLAEPAERYREP 696
                 + T  +P  S  +P+ E     +    + K+  + AE+  EP
Sbjct: 999  TETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEP 1045


>gi|58530845 zyxin [Homo sapiens]
          Length = 572

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 52/214 (24%), Positives = 84/214 (39%), Gaps = 16/214 (7%)

Query: 506 EEKFTSSQTQSPTPPKPPSPSFELG--LSSFPPLPGAAGNLKTEDLFENRLSSLIIGPSK 563
           EE F  +  +    P PP P  E G   +  PP P     + + DL  + LSSL+   +K
Sbjct: 101 EESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLDDMTK 160

Query: 564 ERTLSADASVNTLPVVV-----SREPSVPASCAVSATYE-RSPSPAH-LPDDPKVAEKQR 616
                A  S   +P  V     S+  + PA+   +     +SPS +  LP  P  A+ Q 
Sbjct: 161 NDPFKARVSSGYVPPPVATPFSSKSSTKPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQT 220

Query: 617 ETH---SVDRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKEPPSSPLQPQKEQK 673
           + H        P        ++  V+ A T+ R P         +  P  SP+ P+    
Sbjct: 221 QFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRGPP----ASSPAPAPKFSPVTPKFTPV 276

Query: 674 PNTVGCGKEEKKLAEPAERYREPPALKSTPGAPR 707
            +    G      ++P ++   P AL +  G+P+
Sbjct: 277 ASKFSPGAPGGSGSQPNQKLGHPEALSAGTGSPQ 310


>gi|4508047 zyxin [Homo sapiens]
          Length = 572

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 52/214 (24%), Positives = 84/214 (39%), Gaps = 16/214 (7%)

Query: 506 EEKFTSSQTQSPTPPKPPSPSFELG--LSSFPPLPGAAGNLKTEDLFENRLSSLIIGPSK 563
           EE F  +  +    P PP P  E G   +  PP P     + + DL  + LSSL+   +K
Sbjct: 101 EESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLDDMTK 160

Query: 564 ERTLSADASVNTLPVVV-----SREPSVPASCAVSATYE-RSPSPAH-LPDDPKVAEKQR 616
                A  S   +P  V     S+  + PA+   +     +SPS +  LP  P  A+ Q 
Sbjct: 161 NDPFKARVSSGYVPPPVATPFSSKSSTKPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQT 220

Query: 617 ETH---SVDRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKEPPSSPLQPQKEQK 673
           + H        P        ++  V+ A T+ R P         +  P  SP+ P+    
Sbjct: 221 QFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRGPP----ASSPAPAPKFSPVTPKFTPV 276

Query: 674 PNTVGCGKEEKKLAEPAERYREPPALKSTPGAPR 707
            +    G      ++P ++   P AL +  G+P+
Sbjct: 277 ASKFSPGAPGGSGSQPNQKLGHPEALSAGTGSPQ 310


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 89/370 (24%), Positives = 125/370 (33%), Gaps = 59/370 (15%)

Query: 399 PLTSLRQYPPRS--RNPSKSHLRHAI----PSAERGP---GLLESPSI--FNFTADRLIN 447
           P  S R  PP    R    S   H+     P+A R P   G L+ P+    + +A  L +
Sbjct: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 242

Query: 448 GVRS-PQTRQAGQTRTRIQNPSAYAKREAGPGRVEPGSLESSPGLGRGRKNSFGYRKKRE 506
             RS P  R   +       P     +   P +V P   +++P LG              
Sbjct: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG-------------- 288

Query: 507 EKFTSSQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLKTEDLFENRLSSL-IIGPSKER 565
              +SS   +P+P  PPSPS    L + P  P    +  T  L    L +     PS   
Sbjct: 289 -PLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL 347

Query: 566 TLSADASVNTLPVV----VSREPSVPASCAVSATYERSP------------SPAHLPDDP 609
           +  A       P +    +   PS PAS  +S     SP            +P   P  P
Sbjct: 348 SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 407

Query: 610 KVAEKQRETHSVDRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKEPPSSPLQPQ 669
            V        S    PS   AT       + AA  L+ P            PP SP    
Sbjct: 408 PVQAPFSPPASPPVSPS---ATPPSQAPPSLAAPPLQVP------PSPPASPPMSPSATP 458

Query: 670 KEQKPNTVGCGKEEKKLAEPAERYREPPALKSTP--GAPRDQRRPAGGRPSPSAMGKRLS 727
             Q P  +       +LA+P    + PPAL + P    P       G  P   +    +S
Sbjct: 459 PPQAPPPLAA--PPLQLAKPPP--QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 514

Query: 728 REQSTPPKSP 737
              + PP++P
Sbjct: 515 PLATPPPQAP 524



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 10/85 (11%)

Query: 344 PPMYSPQQQFPLYSLITPQTWSATHSYLDPPLVTPF-------PNTGFINGFTSPAFKPA 396
           PP   P Q     SL +P T  ATHS+L  P ++P        P    +    +P   PA
Sbjct: 318 PPATPPSQATT--SLGSP-TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA 374

Query: 397 ASPLTSLRQYPPRSRNPSKSHLRHA 421
           + PL+ L    P++ N    HL  A
Sbjct: 375 SPPLSPLATPSPQAPNALAVHLLQA 399


>gi|157074225 nuclear pore complex interacting protein-like 3 [Homo
           sapiens]
          Length = 678

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 98/413 (23%), Positives = 143/413 (34%), Gaps = 82/413 (19%)

Query: 344 PPMYSPQQQFPLYSLITPQTWSATHSYLDPP--LVTPFPNTGFINGFTSPAFKPAASPLT 401
           PP      + P   ++TP   SA  +   PP  L+TP P +   N  T P       P +
Sbjct: 294 PPSADDNLKTPPECVLTPLPPSADDNLKTPPECLLTPLPPSADDNLKTPPECLLTPLPPS 353

Query: 402 SLRQYPPRSRNPSKSH---LRHAIPSAERGPGLLESPSIFNFTADRLINGVRSPQTRQAG 458
           +L   PP + +  K+    L H +P +      L++PS      +R +  +       A 
Sbjct: 354 ALPSAPPSADDNLKTRAECLLHPLPPS--ADDNLKTPS------ERQLTPLPPSAPPSAD 405

Query: 459 QTRTRIQNPSAYAKREAGPGRVEPGSLESSPGLGRGRKNSFGYRKKREEKFTSSQTQSPT 518
                I+ P   A+R  GP    P S + +                   K  S +  +P 
Sbjct: 406 DN---IKTP---AERLRGP---LPPSADDNL------------------KTPSERQLTPL 438

Query: 519 PPKPPSPSFELGLSSFPPLPGAAGNLKTEDLFENRLSSLIIGPSKERTLSADASVNTLPV 578
           PP  P              P A  N+KT      RL   +  PS +  L   +     P+
Sbjct: 439 PPSAP--------------PSADDNIKTP---AERLRGPL-PPSADDNLKTPSERQLTPL 480

Query: 579 VVSREPSVPASCAVSATYERSPSPAHLPDDPKV-AEKQRETHSVDRLPSALTATACKSVQ 637
             S  PS   +    A   R P P    D+ K  +E+Q         PSA       + +
Sbjct: 481 PPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAER 540

Query: 638 VNG-----AATELRKPSYAEICQRTSKEPPSSP-------LQPQKEQKPNTVGCGKEEKK 685
           + G     A   L+ P  A   Q    E P  P       ++P  E K   VG       
Sbjct: 541 LRGPLPPSADDNLKTPPLA--TQEAEAEKPRKPKRQRAAEMEPPPEPKRRRVGD------ 592

Query: 686 LAEPAERYREPPALKSTPGAPRDQRRPAGGRPSPSAMGKRLSREQSTPPKSPQ 738
             EP+ + +   A    P +P  +RR  G    PS   KR  R     P SP+
Sbjct: 593 -VEPSRKPKRRRAADVEPSSPEPKRRRVGD-VEPSRKPKR-RRAADVEPSSPE 642


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 56/238 (23%), Positives = 84/238 (35%), Gaps = 17/238 (7%)

Query: 502  RKKREEKFTSSQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLKTEDLFENRLSSLIIGP 561
            R    E+  S     PTP +P SP+  +     P  P AA         E   S     P
Sbjct: 993  RVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPP-----EEPTSPAAAVP 1047

Query: 562  SKERTLSADASVNTLPVVVSREPSVPASCAVSATYERSPSPA-HLPDDPKVAEKQRETHS 620
            + E   S  A+V T       EP+ PA+   +     SP+ A   P++P        T  
Sbjct: 1048 TPEEPTSPAAAVPT-----PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1102

Query: 621  VDRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKEPP-SSPLQPQKEQKPNTVGC 679
                P+A   T  +      A     +P+       T +EP   +P  P  E+  +    
Sbjct: 1103 EPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVA 1162

Query: 680  GKEEKKLAEPAERYREP---PALKSTPGAPRDQRRPAGGRPSPSAMGKRLSREQSTPP 734
                ++ A PA     P    +  +      +   PA   P+P+AM   L  E+ T P
Sbjct: 1163 VPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATL--EEFTSP 1218



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 58/238 (24%), Positives = 82/238 (34%), Gaps = 48/238 (20%)

Query: 507  EKFTSSQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLKTEDLF--------ENRLSSLI 558
            E+ TS     PTP +P SP+  +     P  P AA     E  F        E   S+ +
Sbjct: 1102 EEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAV 1161

Query: 559  IGPSKERTLSADASVNT--------LPVVVSREP-----SVPASCAVSATYERSPSPAHL 605
              P+ E + S  A+V T          V    EP     SVP   A+ AT E   SPA  
Sbjct: 1162 AVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPA-- 1219

Query: 606  PDDPKVAEKQRETHSVDRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKEPPSSP 665
                                 A   T+ +   +  A +   +P+       T +EP SS 
Sbjct: 1220 ---------------------ASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSA 1258

Query: 666  ---LQPQKEQKP-NTVGCGKEEKKLAEPAERYREPPALKSTPGAPRDQRRPAGGRPSP 719
               L P++   P  +V   +E    A       EP +  +    P     PA   P+P
Sbjct: 1259 AAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTP 1316



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 54/241 (22%), Positives = 80/241 (33%), Gaps = 28/241 (11%)

Query: 507  EKFTSSQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLKTEDLF--------ENRLSSLI 558
            E+ TS     PTP +P SP+  +     P  P AA     E           E   S   
Sbjct: 1037 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1096

Query: 559  IGPSKERTLSADASVNT--------LPVVVSREPSVPASCAVSATYERSPSPA-HLPDDP 609
              P+ E   S  A+V T          V    EP+ PA+   +      P+PA   P++ 
Sbjct: 1097 AVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEES 1156

Query: 610  KVAEKQRETHSVDRLPSALTATACKSVQVNGAATELRKPSYAEICQRT------SKEPPS 663
              A     T      P+A   T  +S         L +P+       T      + E  +
Sbjct: 1157 ASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFT 1216

Query: 664  SPLQ--PQKEQKPNTVGCGKEEKKLAEPA---ERYREPPALKSTPGAPRDQRRPAGGRPS 718
            SP    P  E+  +        ++   PA       EP +  +    P +   PA   P+
Sbjct: 1217 SPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPT 1276

Query: 719  P 719
            P
Sbjct: 1277 P 1277


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.128    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,417,844
Number of Sequences: 37866
Number of extensions: 1970216
Number of successful extensions: 10389
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 410
Number of HSP's that attempted gapping in prelim test: 9312
Number of HSP's gapped (non-prelim): 1377
length of query: 738
length of database: 18,247,518
effective HSP length: 110
effective length of query: 628
effective length of database: 14,082,258
effective search space: 8843658024
effective search space used: 8843658024
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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