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Search of human proteins with 5729953
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5729953 nuclear distribution gene C homolog [Homo sapiens]
(331 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5729953 nuclear distribution gene C homolog [Homo sapiens] 662 0.0
gi|122939165 NudC domain containing 3 [Homo sapiens] 135 7e-32
gi|189571679 NudC domain containing 1 isoform 2 [Homo sapiens] 49 8e-06
gi|189571677 NudC domain containing 1 isoform 1 [Homo sapiens] 49 8e-06
gi|38569484 kinesin family member 21A [Homo sapiens] 46 4e-05
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 45 9e-05
gi|148746195 trichohyalin [Homo sapiens] 44 2e-04
gi|21687129 NudC domain containing 2 [Homo sapiens] 44 2e-04
gi|28274705 family with sequence similarity 9, member A [Homo sa... 44 2e-04
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 43 3e-04
gi|4506467 radixin [Homo sapiens] 43 4e-04
gi|7662018 PHD finger protein 3 [Homo sapiens] 42 8e-04
gi|4757900 calreticulin precursor [Homo sapiens] 41 0.001
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 41 0.002
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 40 0.002
gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ... 40 0.003
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 40 0.004
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 40 0.004
gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo sap... 40 0.004
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 39 0.005
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 39 0.005
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 39 0.005
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 39 0.005
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 39 0.005
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 39 0.005
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 39 0.005
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 39 0.005
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 39 0.005
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 39 0.006
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 39 0.006
>gi|5729953 nuclear distribution gene C homolog [Homo sapiens]
Length = 331
Score = 662 bits (1707), Expect = 0.0
Identities = 331/331 (100%), Positives = 331/331 (100%)
Query: 1 MGGEQEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFFIGGEEGMAEKLITQTFS 60
MGGEQEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFFIGGEEGMAEKLITQTFS
Sbjct: 1 MGGEQEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFFIGGEEGMAEKLITQTFS 60
Query: 61 HHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEID 120
HHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEID
Sbjct: 61 HHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEID 120
Query: 121 QKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSE 180
QKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSE
Sbjct: 121 QKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSE 180
Query: 181 LDLAVPFCVNFRLKGKDMVVDIQRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKV 240
LDLAVPFCVNFRLKGKDMVVDIQRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKV
Sbjct: 181 LDLAVPFCVNFRLKGKDMVVDIQRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKV 240
Query: 241 VTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMG 300
VTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMG
Sbjct: 241 VTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMG 300
Query: 301 LPTSDEQKKQEILKKFMDQHPEMDFSKAKFN 331
LPTSDEQKKQEILKKFMDQHPEMDFSKAKFN
Sbjct: 301 LPTSDEQKKQEILKKFMDQHPEMDFSKAKFN 331
>gi|122939165 NudC domain containing 3 [Homo sapiens]
Length = 361
Score = 135 bits (339), Expect = 7e-32
Identities = 94/334 (28%), Positives = 166/334 (49%), Gaps = 27/334 (8%)
Query: 8 ERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFF---------IGGEEGMAEKLITQT 58
E +D LL + Q H G VQ+ + F FL RKTDF+ +G G A+ L+ Q
Sbjct: 7 ELYDQALLGILQ-HVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQALVLQV 65
Query: 59 FSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGP-------QIKELTD-- 109
F + +A++ ++R E + R K E A+ A +E +I T+
Sbjct: 66 FKTFDHMARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDSTTELD 125
Query: 110 --EEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGA 167
+E E++Q K+ A + G++ + E +++ + P+ NGA
Sbjct: 126 GHQEVEKVQPPGPVKEMAHGSQEAEAPGAVAGAAEVPREPPILPRIQEQFQKNPDSYNGA 185
Query: 168 DLPNYRWTQTLSELDLAVPFCVNFRLKGKDMVVDIQRRHLRVGL---KGQPAIIDGELYN 224
NY W+Q ++L++ VP + +KGK + V + +RV + G+ +++G+L +
Sbjct: 186 VRENYTWSQDYTDLEVRVPVPKHV-VKGKQVSVALSSSSIRVAMLEENGERVLMEGKLTH 244
Query: 225 EVKVEESSWLIEDGKVVTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETR 284
++ E S W +E GK V V+L K+ + WW+ ++ + I+ KIN E S ++ +D E +
Sbjct: 245 KINTESSLWSLEPGKCVLVNLSKVGEY-WWNAILEGEEPIDIDKINKERS-MATVDEEEQ 302
Query: 285 SMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMD 318
++++++ +D QK G P S E K E+LKK D
Sbjct: 303 AVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWD 336
>gi|189571679 NudC domain containing 1 isoform 2 [Homo sapiens]
Length = 554
Score = 48.5 bits (114), Expect = 8e-06
Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 13/121 (10%)
Query: 143 QDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELDLAVPFCVNFRLKGKDMVVDI 202
QD EE+ +ED +K K P Y W QT E DL V + +D+ +
Sbjct: 230 QDLEENMDEDISEKIKE----------PLYYWQQT--EDDLTVTIRLPEDSTKEDIQIQF 277
Query: 203 QRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKVVTVHLEKINKMEWWSRLVSSDP 262
H+ + LK ++G+LY+ + E S+W+I++ + + L K N+ W LV D
Sbjct: 278 LPDHINIVLKDHQ-FLEGKLYSSIDHESSTWIIKESNSLEISLIKKNEGLTWPELVIGDK 336
Query: 263 E 263
+
Sbjct: 337 Q 337
>gi|189571677 NudC domain containing 1 isoform 1 [Homo sapiens]
Length = 583
Score = 48.5 bits (114), Expect = 8e-06
Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 13/121 (10%)
Query: 143 QDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELDLAVPFCVNFRLKGKDMVVDI 202
QD EE+ +ED +K K P Y W QT E DL V + +D+ +
Sbjct: 259 QDLEENMDEDISEKIKE----------PLYYWQQT--EDDLTVTIRLPEDSTKEDIQIQF 306
Query: 203 QRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKVVTVHLEKINKMEWWSRLVSSDP 262
H+ + LK ++G+LY+ + E S+W+I++ + + L K N+ W LV D
Sbjct: 307 LPDHINIVLKDHQ-FLEGKLYSSIDHESSTWIIKESNSLEISLIKKNEGLTWPELVIGDK 365
Query: 263 E 263
+
Sbjct: 366 Q 366
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 46.2 bits (108), Expect = 4e-05
Identities = 56/255 (21%), Positives = 113/255 (44%), Gaps = 32/255 (12%)
Query: 73 KRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAENHEAQL 132
K+ ++ +R+EK ++ + KE ++T + +E E E +LE+++ ++ +HE
Sbjct: 542 KKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHE--- 598
Query: 133 KNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGAD-LPNYRWTQTLSELDLAVPFC-VN 190
++ EE+EEED+ D G+ + +D NY + DLA C +
Sbjct: 599 ---------DEEEEEEEEEDDIDGGESSDESDSESDEKANY-------QADLANITCEIA 642
Query: 191 FRLKGKDMVVDIQRR--HLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKVVTVHLEKI 248
+ K D + + Q+R L+ + + ++ ++ + ++E L G V + EK
Sbjct: 643 IKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKI-RDTQLERDQVLQNLGSVESYSEEKA 701
Query: 249 NKMEWWSRLVSSDPEINTKKINPENSKLSDLDSE-TRSMVEKMMYDQRQKSMGLPTSDEQ 307
K V S+ E + +N E +L E R + + Y+++ K + + +
Sbjct: 702 KK-------VRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMK 754
Query: 308 KKQEILKKFMDQHPE 322
K + L K M + E
Sbjct: 755 KTKVRLMKQMKEEQE 769
Score = 32.7 bits (73), Expect = 0.46
Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 3/86 (3%)
Query: 72 EKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAENHEAQ 131
E A E R+ AR + S T P I E E + L KKD E + +
Sbjct: 495 ESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLA---KKDLEKLKRK 551
Query: 132 LKNGSLDSPGKQDTEEDEEEDEKDKG 157
K GK+D + ++E +++KG
Sbjct: 552 EKRKKKSVAGKEDNTDTDQEKKEEKG 577
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 45.1 bits (105), Expect = 9e-05
Identities = 53/244 (21%), Positives = 112/244 (45%), Gaps = 12/244 (4%)
Query: 71 REKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAENHEA 130
R+ + E ++EKAE +L S SG I EL E+ L ++ +K EN +
Sbjct: 2094 RDLKEMCEFLKKEKAEVQRKLGHVRGSGRSGKTIPEL--EKTIGLMKKVVEKVQRENEQL 2151
Query: 131 QLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELDLAVPFCVN 190
+ +G L S + E++ E+ + + KLK +LG+ + T+ ++ N
Sbjct: 2152 KKASGILTSEKMANIEQENEKLKAELEKLKAHLGHQLSMHYESKTKGTEKI-----IAEN 2206
Query: 191 FRLKGKDMVVDIQRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKVVTVHLEKINK 250
RL+ + LR+ K I++ ++ V++EE+ ++ + LE +
Sbjct: 2207 ERLRKELKKETDAAEKLRIA-KNNLEILNEKM--TVQLEETGKRLQFAESRGPQLEGADS 2263
Query: 251 MEWWSRLVSSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQ 310
W S +V+ E K++ + +K + ++ + +V++ +R++ + D +++
Sbjct: 2264 KSWKSIVVTRMYETKLKELETDIAKKNQSITDLKQLVKEA--TEREQKVNKYNEDLEQQI 2321
Query: 311 EILK 314
+ILK
Sbjct: 2322 KILK 2325
Score = 29.6 bits (65), Expect = 3.9
Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 18/109 (16%)
Query: 62 HNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTD------EEAERL 115
+N+L +K + + +E E E + L ++ K TSG Q K LTD EE +R
Sbjct: 1823 NNELQKKQKAYNKILREKE--EIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRK 1880
Query: 116 QLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDE----EEDEKDKGKLK 160
+++ + + + E LK P K+ ++E EE +K + K++
Sbjct: 1881 VKKLENQLEGKVEEVDLK------PMKEKNAKEELIRWEEGKKWQAKIE 1923
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 44.3 bits (103), Expect = 2e-04
Identities = 35/140 (25%), Positives = 67/140 (47%), Gaps = 17/140 (12%)
Query: 43 FIGGEEGMAEKLITQTFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGP 102
F+ E+ + + + + F QL Q+T +E+ RQE R+ E R +E
Sbjct: 1709 FLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREE------- 1761
Query: 103 QIKELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPN 162
++L +E +R E +Q + E E QL++ D ++ EE++ E+++ +L+P
Sbjct: 1762 --QQLRRQERDRKFREEEQLRQ-EREEQQLRSQESD---RKFREEEQLRQEREEQQLRPQ 1815
Query: 163 LGNGADLPNYRWTQTLSELD 182
+G YRW + +L+
Sbjct: 1816 QRDG----KYRWEEEQLQLE 1831
Score = 39.3 bits (90), Expect = 0.005
Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 15/124 (12%)
Query: 52 EKLITQTFSHHNQLA--QKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIK---- 105
E+ + Q QL Q+ RRE+ ++E E+R + ER + K + E +K
Sbjct: 525 EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEE 584
Query: 106 ----ELTDEEAERLQL-----EIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDK 156
L E+ ERL+ E+++ + E E +LK + +Q + EE++E+ +
Sbjct: 585 RRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
Query: 157 GKLK 160
+L+
Sbjct: 645 QQLR 648
Score = 37.0 bits (84), Expect = 0.024
Identities = 35/163 (21%), Positives = 72/163 (44%), Gaps = 36/163 (22%)
Query: 47 EEGMAEKLITQTFSHHNQLAQKT--RREKRARQEAERR--------------EKAERAAR 90
+E ++L + +QL ++ RR++R ++E E R ++ R R
Sbjct: 560 QERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQR 619
Query: 91 LAKEAKSETSGPQI-----------KELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDS 139
L +E E Q+ ++L E+ ER + + ++++ E E +LK +
Sbjct: 620 LKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEE 679
Query: 140 PGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELD 182
+Q+ E+E+E +++ K + +P ++W Q SE D
Sbjct: 680 RREQELAEEEQEQARERIKSR--------IPKWQW-QLESEAD 713
Score = 36.2 bits (82), Expect = 0.042
Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 6/100 (6%)
Query: 57 QTFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAER-- 114
Q H Q ++ RRE+R ++E E R + + + E Q+K D+E ER
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR--DQEEERRE 486
Query: 115 --LQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEED 152
L+LE +++++ + Q + +Q + EEE+
Sbjct: 487 RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEE 526
Score = 36.2 bits (82), Expect = 0.042
Identities = 27/103 (26%), Positives = 49/103 (47%), Gaps = 10/103 (9%)
Query: 64 QLAQKTRREKRAR----QEAERREKAERAARLAKEAKSETSGPQIKELTDEE--AERLQL 117
QL + E+R R +E ERRE+ ER + + + E ++K +EE +RL+
Sbjct: 475 QLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRS 534
Query: 118 EIDQKKDAENHEAQLKNGSLDSPGKQDTEED----EEEDEKDK 156
E +++ E QL + +Q+ E E+E+ +D+
Sbjct: 535 EQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ 577
Score = 35.8 bits (81), Expect = 0.054
Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 5/91 (5%)
Query: 66 AQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDA 125
+Q+ RR+++ R + E K R AK A E + ++L EE E LQ E +K+
Sbjct: 865 SQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKE-QQLLQEEEEELQREEREKRRR 923
Query: 126 ENHEAQLKNGSLDSPGKQDTEEDEEEDEKDK 156
+ E Q + + Q EE +E++K
Sbjct: 924 QEQERQYR----EEEQLQQEEEQLLREEREK 950
Score = 35.4 bits (80), Expect = 0.071
Identities = 25/115 (21%), Positives = 51/115 (44%), Gaps = 15/115 (13%)
Query: 64 QLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKK 123
QL + +E+R +Q+ R ++ R RL +E + E ++K +EE +L ++++
Sbjct: 632 QLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQE 691
Query: 124 DAENH--------------EAQLKNGSLDS-PGKQDTEEDEEEDEKDKGKLKPNL 163
A EA + + S P KQ+ + +E E+ + + + L
Sbjct: 692 QARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESEL 746
Score = 34.7 bits (78), Expect = 0.12
Identities = 22/111 (19%), Positives = 48/111 (43%)
Query: 64 QLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKK 123
+L Q+ + R +E RR++ ER R +E + E +E + L+ + +++
Sbjct: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEE 1174
Query: 124 DAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRW 174
+ + E QL + ++ + EE+E + K K + + +W
Sbjct: 1175 ELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKW 1225
Score = 34.3 bits (77), Expect = 0.16
Identities = 18/93 (19%), Positives = 49/93 (52%), Gaps = 1/93 (1%)
Query: 64 QLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKK 123
Q ++ R+E+ +Q+ RRE+ R + + + + + +E +++ ER + ++ +++
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQL-RRE 342
Query: 124 DAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDK 156
E E QL+ + +Q ++EE+ +++
Sbjct: 343 QEERREQQLRREQEEERREQQLRREQEEERREQ 375
Score = 34.3 bits (77), Expect = 0.16
Identities = 22/92 (23%), Positives = 49/92 (53%), Gaps = 5/92 (5%)
Query: 67 QKTRREKRARQEAE--RREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKD 124
Q+ RRE++ R+E + R ++ R +L +E + E + K + +RL+ E ++++D
Sbjct: 399 QQLRREQQLRREQQLRREQQLRREQQLRREQEEERH--EQKHEQERREQRLKREQEERRD 456
Query: 125 AENHEAQLKNGSLDSPGKQDTEEDEEEDEKDK 156
E + + + KQ + D+EE+ +++
Sbjct: 457 WLKREEETERHEQER-RKQQLKRDQEEERRER 487
Score = 33.5 bits (75), Expect = 0.27
Identities = 22/92 (23%), Positives = 43/92 (46%), Gaps = 8/92 (8%)
Query: 48 EGMAEKLITQTFSHHNQLAQKTRREKRARQEAERR------EKAERAARLAKEAKSETSG 101
E E+ Q QL +K E+R +QE R ++ ER + + + E
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERRE 348
Query: 102 PQIKELTDEEAERLQLEIDQKKDAENHEAQLK 133
Q++ ++E ER + ++ ++++ E E QL+
Sbjct: 349 QQLRR--EQEEERREQQLRREQEEERREQQLR 378
Score = 33.5 bits (75), Expect = 0.27
Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 10/100 (10%)
Query: 57 QTFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQ 116
Q + Q+ REKR RQE ER+ + E + +E Q+ E+ R +
Sbjct: 904 QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEE--------QLLREEREKRRRQE 955
Query: 117 LEIDQKKD--AENHEAQLKNGSLDSPGKQDTEEDEEEDEK 154
E +KD + E QL + +Q+ E+ E+E+
Sbjct: 956 RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEE 995
Score = 33.5 bits (75), Expect = 0.27
Identities = 22/101 (21%), Positives = 46/101 (45%), Gaps = 10/101 (9%)
Query: 64 QLAQKTRREKRARQEAE----------RREKAERAARLAKEAKSETSGPQIKELTDEEAE 113
+L ++ R+E+ +QE E RR++ ER R +E + E +E +
Sbjct: 1075 ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ 1134
Query: 114 RLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEK 154
L+ + ++++ + E QL + +Q+ E E+E+
Sbjct: 1135 ELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
Score = 33.1 bits (74), Expect = 0.35
Identities = 24/119 (20%), Positives = 57/119 (47%), Gaps = 3/119 (2%)
Query: 38 RKTDFFIGGEEGMAEKLITQTFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKS 97
RK + + EE ++ Q + ++ R+ +R ER+E+ ++ RL +E +
Sbjct: 247 RKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL 306
Query: 98 ETSGPQIKELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDK 156
Q +E +++ ER + + +++ E E QL+ + +Q ++EE+ +++
Sbjct: 307 RRK--QEEERREQQEERREQQERREQQEERREQQLRREQ-EERREQQLRREQEEERREQ 362
Score = 33.1 bits (74), Expect = 0.35
Identities = 42/162 (25%), Positives = 75/162 (46%), Gaps = 24/162 (14%)
Query: 4 EQEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFFIGGEEGMAEKLITQTFSHHN 63
EQ+EER + L +Q E Q+L RR+ + EE ++L +
Sbjct: 329 EQQEERREQQL--RREQEERREQQL--------RREQE-----EERREQQLRREQEEERR 373
Query: 64 QLAQKTRREKRARQEAE-RRE---KAERAARLAKEAKSETSGPQIKELTDEEAERLQLEI 119
+ Q+ RRE++ R+E + RRE + E+ R ++ + E + ++L E+ R + E
Sbjct: 374 E--QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE 431
Query: 120 D---QKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGK 158
+ QK + E E +LK + EE+ E E+++ K
Sbjct: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK 473
Score = 33.1 bits (74), Expect = 0.35
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 21/133 (15%)
Query: 37 RRKTDFFIGGEEGMAEKLITQTFSHHNQLAQKTRREKRARQEAERR-----EKAERAARL 91
RRK EE E+ + + Q+ RRE++ R+E E R ++ E RL
Sbjct: 471 RRKQQLKRDQEEERRERWLK--LEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528
Query: 92 AKEAKSETSGPQIKELTDEEAER-LQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDE- 149
+ +SE Q++ +E E+ L+ E +++ + E E +LK +Q+ D+
Sbjct: 529 QQRLRSE---QQLRREQEERREQLLKREEEKRLEQERREQRLKR-------EQEERRDQL 578
Query: 150 --EEDEKDKGKLK 160
E+E+ + +LK
Sbjct: 579 LKREEERRQQRLK 591
Score = 32.7 bits (73), Expect = 0.46
Identities = 22/106 (20%), Positives = 54/106 (50%), Gaps = 6/106 (5%)
Query: 56 TQTFSHHNQLAQKTRREKRAR-QEAERREKAERAARLAKEAKSETSGPQIKELTDEEAER 114
T+ F QL ++ E R + +E +++++ ER R+ +E + + + L EE +
Sbjct: 201 TEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKL 260
Query: 115 LQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLK 160
+ E ++++ + E QL+ +Q+ + +E+E+ + +L+
Sbjct: 261 QEEEPQRQRELQEEEEQLRKLE-----RQELRRERQEEEQQQQRLR 301
Score = 32.7 bits (73), Expect = 0.46
Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 7/101 (6%)
Query: 36 LRRKTDFFIGGEEGMAEKLITQTFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEA 95
LRR+ EE E+ + + Q+ RRE++ R+E E R R +L +E
Sbjct: 300 LRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEER----REQQLRREQ 355
Query: 96 KSETSGPQIKELTDEEAERLQLEIDQKKDAE---NHEAQLK 133
+ E Q++ +EE QL +Q+ E E QL+
Sbjct: 356 EEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLR 396
Score = 32.7 bits (73), Expect = 0.46
Identities = 26/114 (22%), Positives = 51/114 (44%), Gaps = 5/114 (4%)
Query: 43 FIGGEEGMAEKLITQTFSHHNQLAQKTRREKRARQEAER--REKAERAARLAKEAKSETS 100
F+ E+ + + + F Q + RE++ RQ+ +R RE+ ++ +R ++ K
Sbjct: 1376 FLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREE 1435
Query: 101 GPQIKELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEK 154
Q++ +E ER LE +Q+ E H + L ++ +E D K
Sbjct: 1436 EQQVRR---QERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRK 1486
Score = 32.0 bits (71), Expect = 0.78
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 20/100 (20%)
Query: 67 QKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAE 126
Q +E+R RQE +R+ +AE + A E S + +EL EE ++ + E ++K E
Sbjct: 1829 QLEEQEQRLRQERDRQYRAEE-----QFATQEKSRREEQELWQEEEQKRRQERERKLREE 1883
Query: 127 NHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNG 166
+ Q K EE+ + G++K G G
Sbjct: 1884 HIRRQQK---------------EEQRHRQVGEIKSQEGKG 1908
Score = 30.8 bits (68), Expect = 1.7
Identities = 22/85 (25%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 72 EKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAE--NHE 129
E+ R+E E+R ER + +E + + Q+ E R +LE +K+ E E
Sbjct: 1031 EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE 1090
Query: 130 AQLKNGSLDSPGKQDTEEDEEEDEK 154
QL + +Q+ E E+E+
Sbjct: 1091 EQLLREEPEKRRRQERERQCREEEE 1115
Score = 30.8 bits (68), Expect = 1.7
Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 16/122 (13%)
Query: 47 EEGMAEKLITQTFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIK- 105
EE K + QL ++ R EKR RQE +R+ + E +L +E + + Q +
Sbjct: 1302 EEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEE--QLLQEREEQPLRRQERD 1359
Query: 106 ------ELTDEEAERLQLEIDQKKDAE-------NHEAQLKNGSLDSPGKQDTEEDEEED 152
EL +E R LE +Q+ + E QL+ + +QD + E+
Sbjct: 1360 RKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREE 1419
Query: 153 EK 154
E+
Sbjct: 1420 EQ 1421
Score = 30.4 bits (67), Expect = 2.3
Identities = 18/91 (19%), Positives = 41/91 (45%)
Query: 64 QLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKK 123
Q ++ R+++ R+E ++ + ER + +E + ++ +EE R + E +Q +
Sbjct: 1682 QQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLR 1741
Query: 124 DAENHEAQLKNGSLDSPGKQDTEEDEEEDEK 154
E + L+ L ++ +E D K
Sbjct: 1742 RQERYRKILEEEQLRPEREEQQLRRQERDRK 1772
Score = 29.6 bits (65), Expect = 3.9
Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Query: 71 REKRARQEAERREKAERAARLAKE----AKSETSGPQIKELTDEEAERLQLEIDQKKDAE 126
RE R RQE ER+ + E + +E + E Q +E E E LQ E +Q E
Sbjct: 1068 RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127
Query: 127 NHEAQLKNGSLDSPGKQDTEEDEEEDE 153
+ + L+ +++ E +EE++
Sbjct: 1128 REKR--RRQELERQYREEEEVQQEEEQ 1152
Score = 29.3 bits (64), Expect = 5.1
Identities = 33/160 (20%), Positives = 67/160 (41%), Gaps = 10/160 (6%)
Query: 4 EQEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFFIGGEEGMAE--------KLI 55
E+EEER + L + E QEL R + I + E K+
Sbjct: 662 EEEEERLE-QRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVY 720
Query: 56 TQTFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERL 115
++ Q ++ + EKR R+E+E + + E A ++ + + + +E++ER
Sbjct: 721 SRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERG 780
Query: 116 QLEIDQKKD-AENHEAQLKNGSLDSPGKQDTEEDEEEDEK 154
+ + + E E QL+ ++ E+EE++++
Sbjct: 781 RQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQR 820
Score = 28.9 bits (63), Expect = 6.6
Identities = 22/112 (19%), Positives = 54/112 (48%), Gaps = 2/112 (1%)
Query: 43 FIGGEEGMAEKLITQTFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGP 102
F+ E+ + + + F Q ++ R ++ RQ+ +R+ + E R +E + +
Sbjct: 1517 FLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQE 1576
Query: 103 QIKELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEK 154
+ ++ EE ++++ + ++K E+ E QL+ +Q+ + EDE+
Sbjct: 1577 RDRKFRLEE-QKVRRQEQERKFMED-EQQLRRQEGQQQLRQERDRKFREDEQ 1626
>gi|21687129 NudC domain containing 2 [Homo sapiens]
Length = 157
Score = 43.9 bits (102), Expect = 2e-04
Identities = 26/91 (28%), Positives = 49/91 (53%), Gaps = 5/91 (5%)
Query: 173 RWTQTLSELDLAVPFCVNFRLKGKDMVVDIQRRHLRVGLKGQPAIIDGELYNEVKVEESS 232
+W QTL E+ + V R +D+ +Q RH+ + + G+ I+ G+L++ +E +
Sbjct: 20 QWYQTLEEVFIEVQVPPGTR--AQDIQCGLQSRHVALSVGGRE-ILKGKLFDSTIADEGT 76
Query: 233 WLIEDGKVVTVHLEKINK--MEWWSRLVSSD 261
W +ED K+V + L K + W+ L+ S+
Sbjct: 77 WTLEDRKMVRIVLTKTKRDAANCWTSLLESE 107
>gi|28274705 family with sequence similarity 9, member A [Homo
sapiens]
Length = 332
Score = 43.9 bits (102), Expect = 2e-04
Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 9/92 (9%)
Query: 72 EKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAENHEAQ 131
EK+ EAE E A AA A A++ + ++ + DEE E + E +++K+ E E +
Sbjct: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEE--EKEEEEEKEEEEEEGE 241
Query: 132 LKNGSLDSP-------GKQDTEEDEEEDEKDK 156
+ G + G++ EE+EEE+E+++
Sbjct: 242 EEGGGEEGEEGGGGGEGEETEEEEEEEEEEEE 273
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 43.1 bits (100), Expect = 3e-04
Identities = 32/121 (26%), Positives = 53/121 (43%), Gaps = 15/121 (12%)
Query: 42 FFIGGEEGMAEKLITQTFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSG 101
F+ GG+ T+T +HN ++ RE+ RQ RE+ R ++ + E
Sbjct: 379 FWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQRERE--- 435
Query: 102 PQIKELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEED-EEEDEKDKGKLK 160
+ E ER D+++ E + + D +Q + D E+E EK+KGK K
Sbjct: 436 ------REREHER-----DKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPK 484
Query: 161 P 161
P
Sbjct: 485 P 485
Score = 28.5 bits (62), Expect = 8.7
Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
Query: 87 RAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTE 146
RA+ L E +S GP +E + E + + +D ++ +L G SP +++ +
Sbjct: 44 RASDLEDE-ESAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGD 102
Query: 147 EDEEEDEKD 155
E EE+ D
Sbjct: 103 EGEEDRTSD 111
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 42.7 bits (99), Expect = 4e-04
Identities = 38/110 (34%), Positives = 56/110 (50%), Gaps = 19/110 (17%)
Query: 57 QTFSHHNQLAQKTRR-------EKRARQEAERREKAERAARLAKEAKSETSGPQIK---E 106
QT +L ++TR+ KRA++EAER EK RAA AK A ++ + Q+K +
Sbjct: 357 QTIKAQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQ 416
Query: 107 LTDEEAE-----RLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEE 151
L E AE L E +KK+ E E Q K + ++D E+ +EE
Sbjct: 417 LAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFA----AQEDLEKTKEE 462
>gi|7662018 PHD finger protein 3 [Homo sapiens]
Length = 2039
Score = 42.0 bits (97), Expect = 8e-04
Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 12/106 (11%)
Query: 60 SHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKEL---------TDE 110
SHH ++ R EK QE+ER + +R+ ++ KS G + KE TD
Sbjct: 1927 SHH---LKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDG 1983
Query: 111 EAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDK 156
+A R +D+K D E K+ + ++ E+D + KD+
Sbjct: 1984 KASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDR 2029
>gi|4757900 calreticulin precursor [Homo sapiens]
Length = 417
Score = 41.2 bits (95), Expect = 0.001
Identities = 27/70 (38%), Positives = 40/70 (57%), Gaps = 7/70 (10%)
Query: 92 AKEAKSETSG------PQIKELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDT 145
A+E +ET G Q+K+ DEE +RL+ E + KK E EA+ K D ++
Sbjct: 339 AEEFGNETWGVTKAAEKQMKDKQDEE-QRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEED 397
Query: 146 EEDEEEDEKD 155
EED+EEDE++
Sbjct: 398 EEDKEEDEEE 407
Score = 32.0 bits (71), Expect = 0.78
Identities = 13/36 (36%), Positives = 23/36 (63%)
Query: 121 QKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDK 156
Q KD ++ E +LK D K++ E +++ED++DK
Sbjct: 356 QMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDK 391
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/87 (26%), Positives = 49/87 (56%), Gaps = 11/87 (12%)
Query: 72 EKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAENHEAQ 131
E+ +E +R+EK + R KE K +T + ++ +EE ++ + + +KK+ E E +
Sbjct: 20 EEEEEKEGKRKEK-RKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEE 78
Query: 132 LKNGSLDSPGKQDTEEDEEEDEKDKGK 158
+++ EE++EE+EK++G+
Sbjct: 79 ----------EEEEEEEKEEEEKEEGR 95
Score = 39.3 bits (90), Expect = 0.005
Identities = 21/104 (20%), Positives = 51/104 (49%)
Query: 57 QTFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQ 116
+T + ++ + K R+E E+++K + + ++ + E + ++ EE ER +
Sbjct: 18 ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREE 77
Query: 117 LEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLK 160
E +++++ E E + ++ EE+EE+ +K + K K
Sbjct: 78 EEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121
Score = 37.7 bits (86), Expect = 0.014
Identities = 20/90 (22%), Positives = 48/90 (53%), Gaps = 2/90 (2%)
Query: 67 QKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAE 126
+K +++K+ +E E E+ E KE K + + ++ +++ + + E ++K+ E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEE--KEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE 58
Query: 127 NHEAQLKNGSLDSPGKQDTEEDEEEDEKDK 156
+ + K +++ EE+EEE+EK++
Sbjct: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEE 88
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 40.4 bits (93), Expect = 0.002
Identities = 44/149 (29%), Positives = 65/149 (43%), Gaps = 12/149 (8%)
Query: 26 QELVNTFFSFLRRKTDFFIGGEEGMAEKLITQTFSH---HNQLAQKTRREKRARQEAE-- 80
QE + + LRRK + E A KL Q +LAQ R E A +EAE
Sbjct: 727 QEALREEVAQLRRKAEALGDELEAQARKLEAQNTEAARLSKELAQARRAEAEAHREAEAQ 786
Query: 81 -----RREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEID-QKKDAENHEAQLKN 134
R +A AA E+ S+ ++ L ER Q E + + A++ A+ +
Sbjct: 787 AWEQARLREAVEAAGQELESASQEREALVEALAAAGRERRQWEREGSRLRAQSEAAEERM 846
Query: 135 GSLDSPGKQDTEEDEEEDEKDKGKLKPNL 163
L+S G+Q EE E E ++K L+ L
Sbjct: 847 QVLESEGRQHLEEAERE-RREKEALQAEL 874
>gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo
sapiens]
Length = 142
Score = 40.0 bits (92), Expect = 0.003
Identities = 23/83 (27%), Positives = 38/83 (45%)
Query: 58 TFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQL 117
T + +Q ++ RRE++ R+E R EK R KE + E + +E +EE E +
Sbjct: 60 TSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119
Query: 118 EIDQKKDAENHEAQLKNGSLDSP 140
E+ E + + L SP
Sbjct: 120 EVSFSLATRERETETEEKRLISP 142
Score = 30.0 bits (66), Expect = 3.0
Identities = 20/88 (22%), Positives = 45/88 (51%), Gaps = 5/88 (5%)
Query: 63 NQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQK 122
+ +A + R+ + R+E RRE+ R + +E + E + +E +EE E + E +++
Sbjct: 55 HSMAGTSARKSQRREEK-RREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113
Query: 123 KDAENHEAQLKNGSLDSPGKQDTEEDEE 150
++ E E + + ++TE +E+
Sbjct: 114 EEEEEEEVSFSLATRE----RETETEEK 137
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 39.7 bits (91), Expect = 0.004
Identities = 24/80 (30%), Positives = 44/80 (55%), Gaps = 8/80 (10%)
Query: 81 RREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSP 140
R A AA +A+E ++ P +E +EE E ++ E +++ E+ E + K
Sbjct: 96 RLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEK------- 148
Query: 141 GKQDTEEDEEEDEKDKGKLK 160
+++ EEDEEE+EK+ K++
Sbjct: 149 -EEEKEEDEEEEEKEGKKME 167
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 39.7 bits (91), Expect = 0.004
Identities = 46/186 (24%), Positives = 76/186 (40%), Gaps = 21/186 (11%)
Query: 2 GGEQEEERFDGMLLAMAQQHEGGVQELVNT-FFSFLRRKTDFFIGGEEGM--AEKLITQT 58
G E+EEE + EG +VN S LRR DF +E +E L Q
Sbjct: 325 GSEEEEEE--------VPEQEGEPSSIVNVPGESTLRR--DFLRLQQENKERSEALRRQQ 374
Query: 59 FSHHNQLAQK--------TRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDE 110
QL ++ R+KR Q+ E+R + E R +EA+ + Q + +E
Sbjct: 375 LLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEE 434
Query: 111 EAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLP 170
+ +LE +K++ E A+ + ++ + + EEE + + L A L
Sbjct: 435 KRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLL 494
Query: 171 NYRWTQ 176
RW +
Sbjct: 495 ECRWRE 500
>gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo
sapiens]
Length = 373
Score = 39.7 bits (91), Expect = 0.004
Identities = 27/115 (23%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Query: 42 FFIGGEEGMAEKLITQTFSHHNQLAQKTRR-EKRARQEAERREKAERAARLAKEAKSETS 100
+FIG E+ ++L + NQ +K + E+R +++ EK + + E K +
Sbjct: 148 WFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKER 207
Query: 101 GPQI-KELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEK 154
+I KE+ ++ A+ L+ E Q+K E ++ LK + + ++ E+++E+ ++
Sbjct: 208 EQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQ 262
Score = 34.7 bits (78), Expect = 0.12
Identities = 30/108 (27%), Positives = 49/108 (45%), Gaps = 12/108 (11%)
Query: 47 EEGMAEKLITQTFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKE 106
EE K+I + H + QK +K R+E E++ E + AKE + KE
Sbjct: 179 EEREKRKIIAE--EKHKEWVQKKNEQK--RKEREQKINKEMEEKAAKELE--------KE 226
Query: 107 LTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEK 154
E+A+ E +KK+AE E + K + + + +E +E EK
Sbjct: 227 YLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEK 274
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 39.3 bits (90), Expect = 0.005
Identities = 40/174 (22%), Positives = 73/174 (41%), Gaps = 31/174 (17%)
Query: 4 EQEEERFDGMLLAM--AQQHEGGVQELVNTFFSFLRRKTDFFIGGEEGMAEKLITQ---- 57
+QEEER M L A +H+ + ++ F+ R + + E+ + Q
Sbjct: 727 QQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLK----AARQSVYEEKLKQFEER 782
Query: 58 -TFSHHNQLAQKTRREKRAR------------------QEAERREKAERAARLAKEAKSE 98
HN+L ++ R+ K R Q + RE+ ERA R +E +
Sbjct: 783 LAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELR 842
Query: 99 TSGPQIKELTDEEAERLQ--LEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEE 150
++K+L + E ++ Q LEI++++ E +L + SL + + D E
Sbjct: 843 EYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSE 896
Score = 29.6 bits (65), Expect = 3.9
Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 16/82 (19%)
Query: 67 QKTRR--EKRARQEAERREKAER-------------AARLAKEAKSETSGPQIKELTDEE 111
QK R+ E+R RQEA+ REK ER RL + K+E K++ E+
Sbjct: 602 QKVRKAEEERLRQEAKEREK-ERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIED 660
Query: 112 AERLQLEIDQKKDAENHEAQLK 133
E L + K E E + K
Sbjct: 661 LEELDPDFIMAKQVEQLEKEKK 682
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 39.3 bits (90), Expect = 0.005
Identities = 23/99 (23%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Query: 67 QKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAE 126
++ R+E+R R+E + RE+ + +E K E + K++ ++E ER + E ++K E
Sbjct: 132 ERERKEERKREERKERERKKEEREKERERK-ERKKRERKQVGEKEEERKEKERKERKKRE 190
Query: 127 NHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGN 165
+ + K ++ +E ++++E+ K + K N
Sbjct: 191 RNRKERKKERERKERRERKKERKKKEERKKERQKDRQTN 229
Score = 37.4 bits (85), Expect = 0.019
Identities = 29/116 (25%), Positives = 55/116 (47%), Gaps = 10/116 (8%)
Query: 47 EEGMAEKLITQTFSHHNQLAQKTRREKRARQEAERREKAER--AARLAKEAKSETSGPQI 104
E G EK + + ++ +E + +E E+R+K E+ R +KE K +
Sbjct: 80 ERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEER 139
Query: 105 KELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLK 160
K +E ER + + +++K+ E E + + KQ E++EE EK++ + K
Sbjct: 140 KR--EERKERERKKEEREKERERKERKKRE------RKQVGEKEEERKEKERKERK 187
Score = 36.6 bits (83), Expect = 0.032
Identities = 21/92 (22%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
Query: 67 QKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAE 126
++ K+ R+E E+R++ R + K E G + KE + + R + E + ++ E
Sbjct: 54 ERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKE 113
Query: 127 NHEAQLK--NGSLDSPGKQDTEEDEEEDEKDK 156
+ + K G GK+ ++E + E+ K
Sbjct: 114 KRKKKEKKERGRTSKEGKERERKEERKREERK 145
Score = 33.5 bits (75), Expect = 0.27
Identities = 20/94 (21%), Positives = 49/94 (52%), Gaps = 4/94 (4%)
Query: 67 QKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAE 126
++ R+++ +E ER+E+ +R + E + E + KE ++ ER + E ++++ +
Sbjct: 146 ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKE--RKKRERNRKERKKERERK 203
Query: 127 NHEAQLKNGSLDSPGKQDTEEDEEED--EKDKGK 158
+ K K++ ++D + + EK++GK
Sbjct: 204 ERRERKKERKKKEERKKERQKDRQTNWREKERGK 237
Score = 33.1 bits (74), Expect = 0.35
Identities = 22/97 (22%), Positives = 45/97 (46%), Gaps = 3/97 (3%)
Query: 67 QKTRREKRARQEAERREKAERAARLAKEAKSE---TSGPQIKELTDEEAERLQLEIDQKK 123
++ R K+ R+E E +E E+ R KE K + + +E +E + E ++KK
Sbjct: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
Query: 124 DAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLK 160
+ E + K + +E+E ++++ K + K
Sbjct: 152 EEREKERERKERKKRERKQVGEKEEERKEKERKERKK 188
Score = 32.3 bits (72), Expect = 0.60
Identities = 20/99 (20%), Positives = 46/99 (46%), Gaps = 1/99 (1%)
Query: 67 QKTRREKRARQEAE-RREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDA 125
+K R+ +R ++E + R+K ER + + K G + ++ +E + + K+
Sbjct: 74 EKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKER 133
Query: 126 ENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLG 164
E E + + + K++ E E E ++ K + + +G
Sbjct: 134 ERKEERKREERKERERKKEEREKERERKERKKRERKQVG 172
Score = 30.4 bits (67), Expect = 2.3
Identities = 21/95 (22%), Positives = 46/95 (48%), Gaps = 7/95 (7%)
Query: 67 QKTRREKRARQEAERREK-------AERAARLAKEAKSETSGPQIKELTDEEAERLQLEI 119
++ R ++R R+E ++RE+ ER + KE K + ++ E ER + +
Sbjct: 151 KEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210
Query: 120 DQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEK 154
++KK E + + K+ + K+ + + +E +K
Sbjct: 211 ERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 39.3 bits (90), Expect = 0.005
Identities = 21/96 (21%), Positives = 45/96 (46%), Gaps = 6/96 (6%)
Query: 67 QKTRREKRARQEAERREK------AERAARLAKEAKSETSGPQIKELTDEEAERLQLEID 120
+K R+E+R R+ +E +ER +E ++ET + ++ E + + E +
Sbjct: 182 EKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERE 241
Query: 121 QKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDK 156
++K AE A + D +++ + D + D + K
Sbjct: 242 REKQAERERASERETERDKERERERDRDRDRDRRQK 277
Score = 34.3 bits (77), Expect = 0.16
Identities = 20/102 (19%), Positives = 45/102 (44%), Gaps = 5/102 (4%)
Query: 57 QTFSHHNQLAQKTRREKRARQEAERREKA----ERAARLAKEAKSETSGPQIKELTDEEA 112
+T H++ ++ RE+ E ER+ + +R + +E + + + E E
Sbjct: 200 KTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERD 259
Query: 113 ERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEK 154
+ + E D+ +D + + + + D ++ TE D E + K
Sbjct: 260 KERERERDRDRDRDRRQKE-RERQTDRKRQRRTERDRETERK 300
Score = 30.4 bits (67), Expect = 2.3
Identities = 23/111 (20%), Positives = 47/111 (42%), Gaps = 22/111 (19%)
Query: 67 QKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELT------------------ 108
+K RE+ +E ER+ + ER +E K + +E
Sbjct: 315 RKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERE 374
Query: 109 ---DEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDK 156
D ++ R + E ++ +D + + + + D G+++TE+ + E EKD+
Sbjct: 375 RERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEK-QREREKDR 424
Score = 29.6 bits (65), Expect = 3.9
Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 10/90 (11%)
Query: 67 QKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAE 126
+KT RE+ ++AER +ER KE + E + ++ +E ER Q++
Sbjct: 236 RKTERERE--KQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTER 293
Query: 127 NHEAQLKNGSLDSPGKQDTEEDEEEDEKDK 156
+ E + K ++ E E E E+++
Sbjct: 294 DRETERK--------RERQRERERERERNR 315
Score = 29.6 bits (65), Expect = 3.9
Identities = 24/103 (23%), Positives = 48/103 (46%), Gaps = 11/103 (10%)
Query: 67 QKTRREKRARQEAERREKAERAA-------RLAKEAKSETSGP-QIKELTDEEAERL--- 115
++ RE+ + +E ER ++ ER R KE + +T Q + D E ER
Sbjct: 244 KQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRER 303
Query: 116 QLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGK 158
Q E +++++ + + + +++TE D E++ + K K
Sbjct: 304 QRERERERERNRKRERERERERERERQRETERDREKERERKRK 346
Score = 28.5 bits (62), Expect = 8.7
Identities = 19/110 (17%), Positives = 41/110 (37%)
Query: 47 EEGMAEKLITQTFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKE 106
E G + +T + + Q R R R+ REK R ++ + +
Sbjct: 207 ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERER 266
Query: 107 LTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDK 156
D + +R Q E +++ D + ++ + ++ E + E + K
Sbjct: 267 DRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRK 316
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 39.3 bits (90), Expect = 0.005
Identities = 51/273 (18%), Positives = 115/273 (42%), Gaps = 53/273 (19%)
Query: 60 SHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEA-----ER 114
SHH +K E + R EAER ARL E + Q K++ DE A E+
Sbjct: 252 SHH----EKMEEEDKERAEAER-------ARLEAEERERIKAEQDKKIADERARIEAEEK 300
Query: 115 LQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRW 174
+ ++++AE E + + +Q +E+E+ +++ ++K A+
Sbjct: 301 AAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE------ 354
Query: 175 TQTLSELDLAVPFCVNFRLKGKDMVVDIQRRHLRVGLKGQPAIIDGELYNEVKVEESSWL 234
R+K ++ +R+ R + + A ++ + N+ ++EE
Sbjct: 355 --------------ERQRIKEEEKRAAEERQRARAE-EEEKAKVEEQKRNK-QLEEKKHA 398
Query: 235 IEDGKVVTVHLEKINKMEWWSRLVSSDPEINTKKINPE--------NSKLSDLDSETRSM 286
+++ K+ +E+ + +W + + + ++ T + + +K L + +
Sbjct: 399 MQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTF 458
Query: 287 VEKMMYDQRQKSMGLPTSDEQKKQEILKKFMDQ 319
++ + D++ K D++ K+E+ K FMD+
Sbjct: 459 KKEEIKDEKIK------KDKEPKEEV-KSFMDR 484
Score = 31.2 bits (69), Expect = 1.3
Identities = 24/102 (23%), Positives = 47/102 (46%), Gaps = 17/102 (16%)
Query: 72 EKRARQEAERREKAERAARLAKEAKSETSGPQI----KELTDEEAERLQLEIDQKKDAEN 127
E+ AR+E R+++ + A KE + + + + ++ AE E ++K ++
Sbjct: 98 ERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQ 157
Query: 128 HEAQL-----------KNGSLDSPG--KQDTEEDEEEDEKDK 156
++ KN D+ K+D E++EEE+EK K
Sbjct: 158 ERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPK 199
Score = 30.8 bits (68), Expect = 1.7
Identities = 19/66 (28%), Positives = 33/66 (50%)
Query: 68 KTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAEN 127
+ RR + +E E+ ++ ++ A L E + + K L +EE R Q E D+K E
Sbjct: 540 RRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEE 599
Query: 128 HEAQLK 133
+ +LK
Sbjct: 600 EKRRLK 605
Score = 28.9 bits (63), Expect = 6.6
Identities = 53/282 (18%), Positives = 110/282 (39%), Gaps = 33/282 (11%)
Query: 47 EEGMAEKLITQTFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKE 106
E AE+ + A++ ++ R E EKA R +EA+ + ++
Sbjct: 263 ERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEK 322
Query: 107 LTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNG 166
EE +R++ E +K+ AE + + + +Q +E+E+ +++ + +
Sbjct: 323 RAAEERQRIKEE--EKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEK 380
Query: 167 ADLPNYRWTQTLSELDLAVPFCVNFRLKGKDMVVDIQRRHLRVGLKGQPAIIDGELYNEV 226
A + + + L E A+ ++KG+ ++++ I+G+ NE
Sbjct: 381 AKVEEQKRNKQLEEKKHAMQ---ETKIKGE----KVEQK------------IEGKWVNEK 421
Query: 227 KVEESSWLIEDGKVVTVHLEKINKMEWWSRLVSSD-PEINTKKINPENSKLSDLDSETRS 285
K +E ++ + EK K++ + D P ++I E K D E +
Sbjct: 422 KAQEDK--LQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIK---KDKEPKE 476
Query: 286 MVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMDQHPEMDFSK 327
V+ M + G Q + + K +H E FS+
Sbjct: 477 EVKSFM----DRKKGFTEVKSQNGEFMTHKL--KHTENTFSR 512
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 39.3 bits (90), Expect = 0.005
Identities = 27/105 (25%), Positives = 54/105 (51%), Gaps = 11/105 (10%)
Query: 67 QKTRREKRA--RQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKD 124
QK RR ++ ++ ++ RE+ + +R K + + +IKE + + + E +++K+
Sbjct: 345 QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKE 404
Query: 125 AENHEAQLKNGSLDSPGKQDTEEDEEED---------EKDKGKLK 160
E + + KN D ++D E+D+E+D EKD+ K K
Sbjct: 405 REKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 449
Score = 36.2 bits (82), Expect = 0.042
Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 3/97 (3%)
Query: 62 HNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQ 121
H++ +K REK +E + + E+ KE + E + K+ D+E E+ E D+
Sbjct: 372 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKD-RDKEREK-DREKDK 429
Query: 122 KKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGK 158
+KD E + D K+ ++ E+E EKD+ K
Sbjct: 430 EKDREREREKEHEKDRDKE-KEKEQDKEKEREKDRSK 465
Score = 34.3 bits (77), Expect = 0.16
Identities = 21/100 (21%), Positives = 49/100 (49%), Gaps = 6/100 (6%)
Query: 60 SHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEI 119
S ++ + + RR +R+R + ++ R ++ K S + P+ + D++ E+ + I
Sbjct: 487 SRRSRSSSRERRRRRSRSSS----RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHI 542
Query: 120 DQKKDAENHEAQLKNGSLDSPGKQDTEEDEEE-DEKDKGK 158
++++ E ++ S D GK+ E++ EK+ K
Sbjct: 543 SERRERE-RSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNK 581
Score = 30.8 bits (68), Expect = 1.7
Identities = 20/105 (19%), Positives = 46/105 (43%), Gaps = 1/105 (0%)
Query: 64 QLAQKTR-REKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQK 122
++ +K R +EK +E ER ++ E+ K + + +E E+ + E + +
Sbjct: 383 KIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE 442
Query: 123 KDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGA 167
KD + + + ++ + + E DE+ + K + P N +
Sbjct: 443 KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNAS 487
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 39.3 bits (90), Expect = 0.005
Identities = 27/105 (25%), Positives = 54/105 (51%), Gaps = 11/105 (10%)
Query: 67 QKTRREKRA--RQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKD 124
QK RR ++ ++ ++ RE+ + +R K + + +IKE + + + E +++K+
Sbjct: 229 QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKE 288
Query: 125 AENHEAQLKNGSLDSPGKQDTEEDEEED---------EKDKGKLK 160
E + + KN D ++D E+D+E+D EKD+ K K
Sbjct: 289 REKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 333
Score = 36.2 bits (82), Expect = 0.042
Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 3/97 (3%)
Query: 62 HNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQ 121
H++ +K REK +E + + E+ KE + E + K+ D+E E+ E D+
Sbjct: 256 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKD-RDKEREK-DREKDK 313
Query: 122 KKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGK 158
+KD E + D K+ ++ E+E EKD+ K
Sbjct: 314 EKDREREREKEHEKDRDKE-KEKEQDKEKEREKDRSK 349
Score = 34.3 bits (77), Expect = 0.16
Identities = 21/100 (21%), Positives = 49/100 (49%), Gaps = 6/100 (6%)
Query: 60 SHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEI 119
S ++ + + RR +R+R + ++ R ++ K S + P+ + D++ E+ + I
Sbjct: 371 SRRSRSSSRERRRRRSRSSS----RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHI 426
Query: 120 DQKKDAENHEAQLKNGSLDSPGKQDTEEDEEE-DEKDKGK 158
++++ E ++ S D GK+ E++ EK+ K
Sbjct: 427 SERRERE-RSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNK 465
Score = 30.8 bits (68), Expect = 1.7
Identities = 20/105 (19%), Positives = 46/105 (43%), Gaps = 1/105 (0%)
Query: 64 QLAQKTR-REKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQK 122
++ +K R +EK +E ER ++ E+ K + + +E E+ + E + +
Sbjct: 267 KIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE 326
Query: 123 KDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGA 167
KD + + + ++ + + E DE+ + K + P N +
Sbjct: 327 KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNAS 371
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 39.3 bits (90), Expect = 0.005
Identities = 19/85 (22%), Positives = 48/85 (56%)
Query: 72 EKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAENHEAQ 131
++RA + ++ ++ + + ++ +SG ++ + E E +E D ++D E E
Sbjct: 160 DRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDA 219
Query: 132 LKNGSLDSPGKQDTEEDEEEDEKDK 156
++ +D G+++ EE+EEE+E+++
Sbjct: 220 EEDEEVDEDGEEEEEEEEEEEEEEE 244
Score = 34.3 bits (77), Expect = 0.16
Identities = 22/89 (24%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 70 RREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEA---ERLQLEIDQKKDAE 126
RR R+ Q ++ +E + S +S Q +EE E ++ + + ++DAE
Sbjct: 161 RRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAE 220
Query: 127 NHEAQLKNGSLDSPGKQDTEEDEEEDEKD 155
E ++G + +++ EE+EEE+E++
Sbjct: 221 EDEEVDEDGEEEEEEEEEEEEEEEEEEEE 249
Score = 31.6 bits (70), Expect = 1.0
Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 10/100 (10%)
Query: 64 QLAQKTRREKRARQEAE---RREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEID 120
+L+ RE Q + R+ ER A+ SE G ++ ++ + E++
Sbjct: 116 RLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVN 175
Query: 121 QKKDAENHEAQLKNGSLDSPG------KQDTEEDEEEDEK 154
++ +HE +GS D G ++ EED EEDE+
Sbjct: 176 SEEYGSDHETG-SSGSSDEQGNNTENEEEGVEEDVEEDEE 214
Score = 30.8 bits (68), Expect = 1.7
Identities = 23/128 (17%), Positives = 54/128 (42%), Gaps = 16/128 (12%)
Query: 46 GEEGMAEKLITQTFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIK 105
G G +++ T + + + ++ ++AE E+ + +E + E +
Sbjct: 186 GSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE----E 241
Query: 106 ELTDEEAERLQLEIDQKKDAENHEAQ------------LKNGSLDSPGKQDTEEDEEEDE 153
E +EE E Q E DQK++ +++ + +GS+ S D ++++++
Sbjct: 242 EEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKER 301
Query: 154 KDKGKLKP 161
K + P
Sbjct: 302 KRARGISP 309
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 39.3 bits (90), Expect = 0.005
Identities = 49/277 (17%), Positives = 124/277 (44%), Gaps = 21/277 (7%)
Query: 52 EKLITQTFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAK--SETSG-----PQI 104
+++ Q ++++ R ++ R+E ERR + +R A A++ K E G P
Sbjct: 442 DEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSP 501
Query: 105 KELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLG 164
+E+ + E E+ + E +++ + E + + K D +Q+ E++ E++++ + +++
Sbjct: 502 EEIREREREK-EREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERK 560
Query: 165 NGADLPNYRWTQTLSELDLAVPFCVNFRLKGKDMVVDIQRRHLRVGLKGQPAIIDGELYN 224
+ R + EL ++K ++ ++++ ++ K +P + E
Sbjct: 561 QEKEKELERQKEKEKELQ---------KMKEQEKECELEKEREKLEEKIEPREPNLEPMV 611
Query: 225 EVKVEESSWLIEDGKVVTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETR 284
E + E+S E+ V T ++ E + ++PE ++ P + LS + +
Sbjct: 612 EKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQ---PRPAVLSGYFKQFQ 668
Query: 285 SMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMDQHP 321
+ + ++Q+ M +Q++Q +L + + P
Sbjct: 669 KSLPP-RFQRQQEQMKQQQWQQQQQQGVLPQTVPSQP 704
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 39.3 bits (90), Expect = 0.005
Identities = 19/85 (22%), Positives = 48/85 (56%)
Query: 72 EKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAENHEAQ 131
++RA + ++ ++ + + ++ +SG ++ + E E +E D ++D E E
Sbjct: 160 DRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDA 219
Query: 132 LKNGSLDSPGKQDTEEDEEEDEKDK 156
++ +D G+++ EE+EEE+E+++
Sbjct: 220 EEDEEVDEDGEEEEEEEEEEEEEEE 244
Score = 34.3 bits (77), Expect = 0.16
Identities = 22/89 (24%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 70 RREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEA---ERLQLEIDQKKDAE 126
RR R+ Q ++ +E + S +S Q +EE E ++ + + ++DAE
Sbjct: 161 RRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAE 220
Query: 127 NHEAQLKNGSLDSPGKQDTEEDEEEDEKD 155
E ++G + +++ EE+EEE+E++
Sbjct: 221 EDEEVDEDGEEEEEEEEEEEEEEEEEEEE 249
Score = 31.6 bits (70), Expect = 1.0
Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 10/100 (10%)
Query: 64 QLAQKTRREKRARQEAE---RREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEID 120
+L+ RE Q + R+ ER A+ SE G ++ ++ + E++
Sbjct: 116 RLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVN 175
Query: 121 QKKDAENHEAQLKNGSLDSPG------KQDTEEDEEEDEK 154
++ +HE +GS D G ++ EED EEDE+
Sbjct: 176 SEEYGSDHETG-SSGSSDEQGNNTENEEEGVEEDVEEDEE 214
Score = 30.8 bits (68), Expect = 1.7
Identities = 23/128 (17%), Positives = 54/128 (42%), Gaps = 16/128 (12%)
Query: 46 GEEGMAEKLITQTFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIK 105
G G +++ T + + + ++ ++AE E+ + +E + E +
Sbjct: 186 GSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE----E 241
Query: 106 ELTDEEAERLQLEIDQKKDAENHEAQ------------LKNGSLDSPGKQDTEEDEEEDE 153
E +EE E Q E DQK++ +++ + +GS+ S D ++++++
Sbjct: 242 EEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKER 301
Query: 154 KDKGKLKP 161
K + P
Sbjct: 302 KRARGISP 309
>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
sapiens]
Length = 1632
Score = 38.9 bits (89), Expect = 0.006
Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 11/98 (11%)
Query: 67 QKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDA- 125
++ + R +E ER EK E+ RL + K T ++KE D EA R ++ D+ +D
Sbjct: 239 ERAKSGTRTEKEEERDEKEEK--RLRSQTKEPTPKQKLKEEPDREA-RAGVQADEDEDGD 295
Query: 126 ENHEAQLKNGSLDSPGKQDTEEDEEE-------DEKDK 156
E E + ++ D K+ EE E E DEKD+
Sbjct: 296 EKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDE 333
Score = 33.9 bits (76), Expect = 0.21
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 68 KTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAEN 127
K + EKR R + R A + AKS T + +E ++E +RL+ Q K+
Sbjct: 214 KDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLR---SQTKEPTP 270
Query: 128 HEAQLKNGSLDSPGKQDTEEDEEEDEKDKGK 158
+ + ++ +EDE+ DEKD+ K
Sbjct: 271 KQKLKEEPDREARAGVQADEDEDGDEKDEKK 301
>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
sapiens]
Length = 1616
Score = 38.9 bits (89), Expect = 0.006
Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 11/98 (11%)
Query: 67 QKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDA- 125
++ + R +E ER EK E+ RL + K T ++KE D EA R ++ D+ +D
Sbjct: 223 ERAKSGTRTEKEEERDEKEEK--RLRSQTKEPTPKQKLKEEPDREA-RAGVQADEDEDGD 279
Query: 126 ENHEAQLKNGSLDSPGKQDTEEDEEE-------DEKDK 156
E E + ++ D K+ EE E E DEKD+
Sbjct: 280 EKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDE 317
Score = 33.9 bits (76), Expect = 0.21
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 68 KTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAEN 127
K + EKR R + R A + AKS T + +E ++E +RL+ Q K+
Sbjct: 198 KDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLR---SQTKEPTP 254
Query: 128 HEAQLKNGSLDSPGKQDTEEDEEEDEKDKGK 158
+ + ++ +EDE+ DEKD+ K
Sbjct: 255 KQKLKEEPDREARAGVQADEDEDGDEKDEKK 285
Score = 29.3 bits (64), Expect = 5.1
Identities = 23/114 (20%), Positives = 55/114 (48%), Gaps = 22/114 (19%)
Query: 68 KTRREKRARQEAERREKAERAARLAKEAKSETS-------GPQIKELTDEEAERLQLEID 120
K R +R++ + E + + + R+ +++ +T+ GP K EE+ER + +
Sbjct: 134 KPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPA-KRKPQEESERAKSDES 192
Query: 121 QKKDAENHEAQLKNGS----------LDSPGKQD----TEEDEEEDEKDKGKLK 160
K++ ++ + + + + + P + TE++EE DEK++ +L+
Sbjct: 193 IKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLR 246
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,473,619
Number of Sequences: 37866
Number of extensions: 579376
Number of successful extensions: 8394
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 263
Number of HSP's successfully gapped in prelim test: 523
Number of HSP's that attempted gapping in prelim test: 5025
Number of HSP's gapped (non-prelim): 2834
length of query: 331
length of database: 18,247,518
effective HSP length: 103
effective length of query: 228
effective length of database: 14,347,320
effective search space: 3271188960
effective search space used: 3271188960
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.