BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|56549129 transmembrane anchor protein 1 isoform 3 [Homo sapiens] (170 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|56549129 transmembrane anchor protein 1 isoform 3 [Homo sapiens] 346 6e-96 gi|56549133 transmembrane anchor protein 1 isoform 2 [Homo sapiens] 342 1e-94 gi|56549131 transmembrane anchor protein 1 isoform 1 [Homo sapiens] 341 2e-94 gi|110832843 TBP-associated factor 4 [Homo sapiens] 55 3e-08 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 54 5e-08 gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [... 53 1e-07 gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 53 1e-07 gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 53 1e-07 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 53 1e-07 gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 53 1e-07 gi|23503317 coiled-coil domain containing 96 [Homo sapiens] 52 2e-07 gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 52 3e-07 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 51 4e-07 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 51 4e-07 gi|24308115 interferon regulatory factor 2 binding protein 1 [Ho... 51 5e-07 gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 50 7e-07 gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 50 7e-07 gi|153070260 myristoylated alanine-rich protein kinase C substra... 50 7e-07 gi|32307177 forkhead box G1 [Homo sapiens] 50 7e-07 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 50 1e-06 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 50 1e-06 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 50 1e-06 gi|194578898 hypothetical protein LOC100170841 [Homo sapiens] 49 2e-06 gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 49 2e-06 gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 49 2e-06 gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 49 2e-06 gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ... 49 2e-06 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 49 2e-06 gi|27894378 chloride intracellular channel 6 [Homo sapiens] 49 2e-06 gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 48 4e-06 >gi|56549129 transmembrane anchor protein 1 isoform 3 [Homo sapiens] Length = 170 Score = 346 bits (887), Expect = 6e-96 Identities = 170/170 (100%), Positives = 170/170 (100%) Query: 1 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC Sbjct: 1 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60 Query: 61 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL Sbjct: 61 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120 Query: 121 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE Sbjct: 121 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170 >gi|56549133 transmembrane anchor protein 1 isoform 2 [Homo sapiens] Length = 177 Score = 342 bits (876), Expect = 1e-94 Identities = 168/169 (99%), Positives = 168/169 (99%) Query: 1 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC Sbjct: 1 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60 Query: 61 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL Sbjct: 61 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120 Query: 121 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTE 169 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQR E Sbjct: 121 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRIE 169 >gi|56549131 transmembrane anchor protein 1 isoform 1 [Homo sapiens] Length = 204 Score = 341 bits (875), Expect = 2e-94 Identities = 167/170 (98%), Positives = 169/170 (99%) Query: 1 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC Sbjct: 1 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60 Query: 61 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL Sbjct: 61 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120 Query: 121 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQR ++ Sbjct: 121 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRVQK 170 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 55.1 bits (131), Expect = 3e-08 Identities = 43/111 (38%), Positives = 50/111 (45%), Gaps = 15/111 (13%) Query: 31 AAASPEPARAPPEPAPPAEATGA--------PAPSRPCAPEPAASPAGPEEPGEPAGLGE 82 A A PA APP P PPA AT A P + P P PAA+ G PA Sbjct: 260 APAPAAPAAAPPPP-PPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPA 318 Query: 83 LGEPAGPGEPEGPGDPAAAP-----AEAEEQAVEARQEEEQDLDGEKGPSS 128 G PAG GPG AAAP AE+ ++ V+A Q L GP+S Sbjct: 319 AGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTL-AASGPAS 368 Score = 48.9 bits (115), Expect = 2e-06 Identities = 36/95 (37%), Positives = 41/95 (43%), Gaps = 9/95 (9%) Query: 28 RRGAAASPEPARAPPEPAPPAEATGAP--APSRPCAPEPAASP--AGPEE----PGEPAG 79 +R SP P PAPPA P + CAP PAA+ AGPE P +PAG Sbjct: 103 QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG 162 Query: 80 LGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQ 114 L AGPG GPG P P + A Q Sbjct: 163 PAALAARAGPGPGPGPG-PGPGPGPGKPAGPGAAQ 196 Score = 45.8 bits (107), Expect = 2e-05 Identities = 39/112 (34%), Positives = 43/112 (38%), Gaps = 39/112 (34%) Query: 30 GAAASPEPA-RAPPEPAPPAEATGAPAPSRP-----------------------CAPEPA 65 GAA P PA RA P P + G P+P RP CAP PA Sbjct: 84 GAAPEPPPAGRARPGGGGP-QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPA 142 Query: 66 A---------SPAGPEEPGEPAGLGELGEPA-----GPGEPEGPGDPAAAPA 103 A +PAGP +P PA L P GPG GPG PA A Sbjct: 143 AAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGA 194 Score = 43.5 bits (101), Expect = 9e-05 Identities = 47/115 (40%), Positives = 53/115 (46%), Gaps = 28/115 (24%) Query: 1 MEAPAELLAALPALATALALLLAWLLVRRGAAAS---PEPA------RAPP---EPAPPA 48 + A LL + A A A++L V G AA P+PA + PP APPA Sbjct: 198 LNGSAALLNSHHAAAPAVSL------VNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPA 251 Query: 49 EATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPA 103 A APS P AP PAA A P P PA L P PG P GP P AAPA Sbjct: 252 PA----APSPPAAPAPAAPAAAPP-PPPPAP-ATLARP--PGHPAGP--PTAAPA 296 Score = 38.5 bits (88), Expect = 0.003 Identities = 22/57 (38%), Positives = 24/57 (42%), Gaps = 7/57 (12%) Query: 44 PAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAA 100 PA PAE AP P A GP+ PG P+ P P P GP PAA Sbjct: 75 PAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPS-------PRRPLVPAGPAPPAA 124 Score = 37.4 bits (85), Expect = 0.006 Identities = 39/120 (32%), Positives = 42/120 (35%), Gaps = 11/120 (9%) Query: 30 GAAASPEPAR-APPEPAPPAEAT-GAPAPSRPCAPEPAA--SPAGPEEPG---EPAGLGE 82 G AA E A A PEP P A G P RP P P PAGP P P G Sbjct: 74 GPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGS 133 Query: 83 LGE----PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEG 138 G PA GP A PA+ A A + G GP + G G Sbjct: 134 AGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPG 193 Score = 33.1 bits (74), Expect = 0.12 Identities = 37/121 (30%), Positives = 41/121 (33%), Gaps = 14/121 (11%) Query: 3 APAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAP 62 A E A PA A L A G P P P +PA P A + Sbjct: 148 AGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNS 207 Query: 63 EPAASPAGPEEPGEPAGLGELGEPAGPG------------EPEGPG--DPAAAPAEAEEQ 108 AA+PA PA L L +PA PG P P P AAPA A Sbjct: 208 HHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPA 267 Query: 109 A 109 A Sbjct: 268 A 268 Score = 30.8 bits (68), Expect = 0.59 Identities = 26/83 (31%), Positives = 29/83 (34%), Gaps = 1/83 (1%) Query: 31 AAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPA-GLGELGEPAGP 89 A+A+ AP P A A GA A+ AGP P E A G PAG Sbjct: 35 ASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGR 94 Query: 90 GEPEGPGDPAAAPAEAEEQAVEA 112 P G G P V A Sbjct: 95 ARPGGGGPQRPGPPSPRRPLVPA 117 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 54.3 bits (129), Expect = 5e-08 Identities = 45/150 (30%), Positives = 60/150 (40%), Gaps = 14/150 (9%) Query: 32 AASPEPARAPPEPA--PPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89 A + P +PP PA P E AP P P P P P P P L G P G Sbjct: 812 APTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLP--PPQLVPEGTPGGG 869 Query: 90 GEPE----------GPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGF 139 G P D E EE+ E +EEE+D + E+ E EEE+ E Sbjct: 870 GPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEE 929 Query: 140 SFKYSPGKLRGNQYKKMMTKEELEEEQRTE 169 F+ + G ++ ++E EEE+ E Sbjct: 930 EFEEEFEEEEGELEEEEEEEDEEEEEELEE 959 Score = 51.6 bits (122), Expect = 3e-07 Identities = 49/163 (30%), Positives = 66/163 (40%), Gaps = 31/163 (19%) Query: 37 PARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGP--EEPGE-PAGLGELGEPAGP---- 89 P PP P PP P P P P P ASP P EEP E PA G L P P Sbjct: 792 PEGLPPLPPPPPSGA-TPPPIAPTGP-PTASPPVPAKEEPEELPAAPGPLPPPPPPPPPV 849 Query: 90 --------------GEPEGPGDPAAAP--------AEAEEQAVEARQEEEQDLDGEKGPS 127 G P G G PA + EE+ E +EEE++ + E+ Sbjct: 850 PGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEED 909 Query: 128 SEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170 E EE++ E F + + ++++ + E EEE+ EE Sbjct: 910 FEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEE 952 Score = 33.9 bits (76), Expect = 0.069 Identities = 18/55 (32%), Positives = 22/55 (40%), Gaps = 4/55 (7%) Query: 34 SPEPARAPP----EPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELG 84 +P P RAPP P P + + P P P+A P PG P LG Sbjct: 656 APSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLG 710 Score = 33.9 bits (76), Expect = 0.069 Identities = 41/149 (27%), Positives = 53/149 (35%), Gaps = 20/149 (13%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASP-AGPEEPGEPAGLGELGEPAG 88 G A APP P P P P P + P PE EP L E+ EP Sbjct: 966 GTAGGEVEEGAPPPPTLP-----------PALPPPESPPKVQPEPEPEPGLLLEVEEPGT 1014 Query: 89 PGEPEGPGDPAAAPAEAEEQAVEARQEEE-------QDLDGEKGPSSEGPEEEDGEGFSF 141 E P AP Q R+ E Q+L E+ + EE+ E S Sbjct: 1015 EEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSD 1074 Query: 142 KYSPGKLRGNQYKKMMTKEELEEEQRTEE 170 K P + ++M T+ E E Q E+ Sbjct: 1075 KVQPPPETPAE-EEMETETEAEALQEKEQ 1102 Score = 30.8 bits (68), Expect = 0.59 Identities = 36/132 (27%), Positives = 40/132 (30%), Gaps = 39/132 (29%) Query: 27 VRRGAAASPE--PARAPPEPAPPAEATGAPAP-------------------SRPCAPEPA 65 V GA P PA PPE P + P P + APE Sbjct: 972 VEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEAL 1031 Query: 66 ASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD---------------PAAAPAEAE---E 107 S E GE G + EP P P PAE E E Sbjct: 1032 PSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETE 1091 Query: 108 QAVEARQEEEQD 119 EA QE+EQD Sbjct: 1092 TEAEALQEKEQD 1103 Score = 26.9 bits (58), Expect = 8.5 Identities = 24/71 (33%), Positives = 25/71 (35%), Gaps = 13/71 (18%) Query: 37 PARAPPEPAPPAEATG---APAPSRPCAPEPAAS---PAGPEEPGEPAGLGELGEPAGPG 90 P P P PP EA AP P P P P+ AGP P AGP Sbjct: 643 PTCPTPAPVPPPEAPSPFRAP-PFHPPGPMPSVGSMPSAGPMPSAGPM------PSAGPV 695 Query: 91 EPEGPGDPAAA 101 PG P A Sbjct: 696 PSARPGPPTTA 706 >gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo sapiens] Length = 1584 Score = 53.1 bits (126), Expect = 1e-07 Identities = 36/96 (37%), Positives = 42/96 (43%), Gaps = 4/96 (4%) Query: 32 AASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPA--GLGELGEPAG- 88 A SP P+R PP PP P P P P P P P EPA LG+ GEPA Sbjct: 1390 ARSP-PSRQPPSGGPPEAPPAQPPPPPPPPPPPPQQPLPPPPNLEPAPPSLGDPGEPAAH 1448 Query: 89 PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEK 124 PG GP A ++E R+ +LD EK Sbjct: 1449 PGPSTGPSTKNENVATLSVSSLERRKSRYAELDFEK 1484 >gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] Length = 1120 Score = 53.1 bits (126), Expect = 1e-07 Identities = 40/131 (30%), Positives = 47/131 (35%), Gaps = 31/131 (23%) Query: 26 LVRRGAAASPEPARAPPE--------------PAPPAEATGAPAPSRPCAPEPAASPAGP 71 LVR + +P PAR P P PP + PS P P GP Sbjct: 756 LVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPE--PPPLDESPGP 813 Query: 72 EEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGP 131 +E L EPAGP EP GP PA ++ EE+ E GP P Sbjct: 814 KEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEE--------------EPGPEGTPP 859 Query: 132 EE-EDGEGFSF 141 GEG F Sbjct: 860 SRGSSGEGLPF 870 Score = 42.4 bits (98), Expect = 2e-04 Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 5/83 (6%) Query: 34 SPEPARAPPEPAPPAEATGAPAPSRPCAPEPA--ASPAGPEEPGEPAGLGELGEPAGPGE 91 SPEP PP P GA P R EPA + P GP P PA E EP G Sbjct: 801 SPEP---PPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGT 857 Query: 92 PEGPGDPAAAPAEAEEQAVEARQ 114 P G AEE + +Q Sbjct: 858 PPSRGSSGEGLPFAEEGNLTIKQ 880 Score = 41.6 bits (96), Expect = 3e-04 Identities = 31/82 (37%), Positives = 35/82 (42%), Gaps = 14/82 (17%) Query: 31 AAASPEPARAPPEP----APPAEATGAPAPSR--------PCAPEPAASPAGPEEPGEPA 78 A+A+P PA P P +PPA + P PS P AP PA P P PG Sbjct: 930 ASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPG--P 987 Query: 79 GLGELGEPAGPGEPEGPGDPAA 100 GL GE E P PAA Sbjct: 988 GLESSAASRWNGETEPPAAPAA 1009 Score = 34.3 bits (77), Expect = 0.053 Identities = 41/146 (28%), Positives = 56/146 (38%), Gaps = 18/146 (12%) Query: 2 EAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPA-PSRPC 60 E PA A P L T L+ L A PEP PP +P E+ GA + S Sbjct: 573 EGPA---TAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHS 629 Query: 61 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120 +PA P+G G+P+ E P G P P ++ P + V + Sbjct: 630 QEQPAPQPSG----GDPSPPQERNLPEGTERP--PKLCSSLPGQGPPPYV--------FM 675 Query: 121 DGEKGPSSEGPEEEDGEGFSFKYSPG 146 + PSS P G ++F Y G Sbjct: 676 YPQGSPSSPAPGPPPGAPWAFSYLAG 701 Score = 30.4 bits (67), Expect = 0.77 Identities = 25/84 (29%), Positives = 31/84 (36%), Gaps = 4/84 (4%) Query: 33 ASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAG---LGELGEPAGP 89 A P PP PA PA T P P P+ +G P G + + +PAGP Sbjct: 829 AGPSEPPGPPAPAGPASDTEEEEPG-PEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGP 887 Query: 90 GEPEGPGDPAAAPAEAEEQAVEAR 113 E P P E V+ R Sbjct: 888 PPRETPVPPGLDFNLTESDTVKRR 911 Score = 28.5 bits (62), Expect = 2.9 Identities = 21/63 (33%), Positives = 24/63 (38%), Gaps = 5/63 (7%) Query: 35 PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG--PGEP 92 P+ + + P P PP GAP A PA P P L G G GE Sbjct: 677 PQGSPSSPAPGPPP---GAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEA 733 Query: 93 EGP 95 EGP Sbjct: 734 EGP 736 >gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] Length = 1202 Score = 53.1 bits (126), Expect = 1e-07 Identities = 40/131 (30%), Positives = 47/131 (35%), Gaps = 31/131 (23%) Query: 26 LVRRGAAASPEPARAPPE--------------PAPPAEATGAPAPSRPCAPEPAASPAGP 71 LVR + +P PAR P P PP + PS P P GP Sbjct: 838 LVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPE--PPPLDESPGP 895 Query: 72 EEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGP 131 +E L EPAGP EP GP PA ++ EE+ E GP P Sbjct: 896 KEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEE--------------EPGPEGTPP 941 Query: 132 EE-EDGEGFSF 141 GEG F Sbjct: 942 SRGSSGEGLPF 952 Score = 42.4 bits (98), Expect = 2e-04 Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 5/83 (6%) Query: 34 SPEPARAPPEPAPPAEATGAPAPSRPCAPEPA--ASPAGPEEPGEPAGLGELGEPAGPGE 91 SPEP PP P GA P R EPA + P GP P PA E EP G Sbjct: 883 SPEP---PPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGT 939 Query: 92 PEGPGDPAAAPAEAEEQAVEARQ 114 P G AEE + +Q Sbjct: 940 PPSRGSSGEGLPFAEEGNLTIKQ 962 Score = 41.6 bits (96), Expect = 3e-04 Identities = 31/82 (37%), Positives = 35/82 (42%), Gaps = 14/82 (17%) Query: 31 AAASPEPARAPPEP----APPAEATGAPAPSR--------PCAPEPAASPAGPEEPGEPA 78 A+A+P PA P P +PPA + P PS P AP PA P P PG Sbjct: 1012 ASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPG--P 1069 Query: 79 GLGELGEPAGPGEPEGPGDPAA 100 GL GE E P PAA Sbjct: 1070 GLESSAASRWNGETEPPAAPAA 1091 Score = 34.3 bits (77), Expect = 0.053 Identities = 41/146 (28%), Positives = 56/146 (38%), Gaps = 18/146 (12%) Query: 2 EAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPA-PSRPC 60 E PA A P L T L+ L A PEP PP +P E+ GA + S Sbjct: 655 EGPA---TAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHS 711 Query: 61 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120 +PA P+G G+P+ E P G P P ++ P + V + Sbjct: 712 QEQPAPQPSG----GDPSPPQERNLPEGTERP--PKLCSSLPGQGPPPYV--------FM 757 Query: 121 DGEKGPSSEGPEEEDGEGFSFKYSPG 146 + PSS P G ++F Y G Sbjct: 758 YPQGSPSSPAPGPPPGAPWAFSYLAG 783 Score = 30.4 bits (67), Expect = 0.77 Identities = 25/84 (29%), Positives = 31/84 (36%), Gaps = 4/84 (4%) Query: 33 ASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAG---LGELGEPAGP 89 A P PP PA PA T P P P+ +G P G + + +PAGP Sbjct: 911 AGPSEPPGPPAPAGPASDTEEEEPG-PEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGP 969 Query: 90 GEPEGPGDPAAAPAEAEEQAVEAR 113 E P P E V+ R Sbjct: 970 PPRETPVPPGLDFNLTESDTVKRR 993 Score = 28.5 bits (62), Expect = 2.9 Identities = 21/63 (33%), Positives = 24/63 (38%), Gaps = 5/63 (7%) Query: 35 PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG--PGEP 92 P+ + + P P PP GAP A PA P P L G G GE Sbjct: 759 PQGSPSSPAPGPPP---GAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEA 815 Query: 93 EGP 95 EGP Sbjct: 816 EGP 818 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 52.8 bits (125), Expect = 1e-07 Identities = 39/101 (38%), Positives = 51/101 (50%), Gaps = 6/101 (5%) Query: 70 GPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE 129 G EE GE G E GE G GE EG G+ E EE+ E EEE +GE+ E Sbjct: 948 GEEEEGEWEGEEEEGE--GEGEEEGEGEGEEGEGEGEEEEGEGEGEEE---EGEEEGEEE 1002 Query: 130 GPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170 G EE+GEG + G++ G + + + E EEE+ EE Sbjct: 1003 GEGEEEGEGEGEEEEEGEVEG-EVEGEEGEGEGEEEEGEEE 1042 Score = 46.2 bits (108), Expect = 1e-05 Identities = 37/100 (37%), Positives = 47/100 (47%), Gaps = 5/100 (5%) Query: 73 EPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDG-EKGPSSEGP 131 E GE G E GE G E EG G+ E EE+ +EEE + G E+G EG Sbjct: 872 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGE 931 Query: 132 -EEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170 EEE+GEG + G+ G + + EE E E EE Sbjct: 932 GEEEEGEG---EGEDGEGEGEEEEGEWEGEEEEGEGEGEE 968 Score = 44.3 bits (103), Expect = 5e-05 Identities = 38/109 (34%), Positives = 51/109 (46%), Gaps = 12/109 (11%) Query: 72 EEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQE-EEQDLDGE------K 124 EE GE G E GE G E EG G+ + EE+ E E EE++ +GE + Sbjct: 888 EEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGE 947 Query: 125 GPSSEGP---EEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170 G EG EEE+GEG + G+ G + + +EE E E EE Sbjct: 948 GEEEEGEWEGEEEEGEGEGEEEGEGE--GEEGEGEGEEEEGEGEGEEEE 994 Score = 43.9 bits (102), Expect = 7e-05 Identities = 37/104 (35%), Positives = 47/104 (45%), Gaps = 3/104 (2%) Query: 70 GPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQE-EEQDLDGEKGPSS 128 G EE GE G E GE G E EG + E EE VE E EE + +GE+ Sbjct: 981 GEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGE 1040 Query: 129 EGPEE--EDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170 E EE ++GEG + + + + K T EE E Q EE Sbjct: 1041 EEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEE 1084 Score = 40.4 bits (93), Expect = 7e-04 Identities = 34/100 (34%), Positives = 47/100 (47%), Gaps = 6/100 (6%) Query: 70 GPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAV-EARQEEEQDLDGE-KGPS 127 G E E G GE E G GE E + E EE+ E +EEE +++GE +G Sbjct: 970 GEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEE 1029 Query: 128 SEGP-EEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQ 166 EG EEE+GE + + G + +EE EEE+ Sbjct: 1030 GEGEGEEEEGEE---EGEEREKEGEGEENRRNREEEEEEE 1066 Score = 40.0 bits (92), Expect = 0.001 Identities = 40/111 (36%), Positives = 50/111 (45%), Gaps = 18/111 (16%) Query: 69 AGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEA----RQEEEQDLDGE- 123 AG EE GE G GE E EG G+ E E VE R+EEE++ +GE Sbjct: 781 AGKEEKGEEEGDQGEGEEE---ETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEE 837 Query: 124 ---KGPSSEGP-EEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170 +G EG EEE+GEG G+ G + + EE E E EE Sbjct: 838 EEGEGEEEEGEGEEEEGEG------KGEEEGEEGEGEEEGEEGEGEGEEEE 882 Score = 39.7 bits (91), Expect = 0.001 Identities = 37/104 (35%), Positives = 49/104 (47%), Gaps = 12/104 (11%) Query: 72 EEPGEPAGLGELGEPAGPGEP-----EGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGP 126 EE GE G E GE G GE EG G+ E E+ E +EEE + +GE+ Sbjct: 905 EEEGEGEGEEEEGE--GKGEEEGEEGEGEGEEEEGEGEGEDGEGEG-EEEEGEWEGEE-E 960 Query: 127 SSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170 EG EE+GEG + G+ G + + EE E E+ EE Sbjct: 961 EGEGEGEEEGEG---EGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001 Score = 39.3 bits (90), Expect = 0.002 Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 8/100 (8%) Query: 70 GPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEE---EQDLDGEKGP 126 G EE G+ E E G G+ EG G+ E EE E ++EE +++ E+G Sbjct: 738 GEEEEGDRE---EEEEKEGEGKEEGEGEEVEGEREKEEG--ERKKEERAGKEEKGEEEGD 792 Query: 127 SSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQ 166 EG EEE K G++ G + ++ + E EEE+ Sbjct: 793 QGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEE 832 Score = 39.3 bits (90), Expect = 0.002 Identities = 35/101 (34%), Positives = 48/101 (47%), Gaps = 4/101 (3%) Query: 72 EEPGEPAGLGELGEPAGPGEPEGP-GDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEG 130 EE GE G GE+ E G E E G+ E EE+ E +EE + E+G EG Sbjct: 809 EEGGEVEG-GEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEG 867 Query: 131 PEE-EDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170 EE E+GEG + G+ G + + +EE E + EE Sbjct: 868 EEEGEEGEG-EGEEEEGEGEGEEEGEGEGEEEEGEGEGEEE 907 Score = 39.3 bits (90), Expect = 0.002 Identities = 36/107 (33%), Positives = 48/107 (44%), Gaps = 8/107 (7%) Query: 70 GPEEPGE---PAGLGELGEPAGPGEPEGP---GDPAAAPAEAEEQAVEARQEEEQDLDGE 123 G EE GE G GE E G GE EG G+ E E + E E E++ +GE Sbjct: 835 GEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGE 894 Query: 124 -KGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTE 169 + EG EE+GEG + G+ +G + + E EEE E Sbjct: 895 GEEEEGEGEGEEEGEG-EGEEEEGEGKGEEEGEEGEGEGEEEEGEGE 940 Score = 34.7 bits (78), Expect = 0.041 Identities = 36/110 (32%), Positives = 50/110 (45%), Gaps = 16/110 (14%) Query: 72 EEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGP 131 EE GE G E E G GE E G+ E E + E R+ E++ + E+G E Sbjct: 1016 EEEGEVEGEVEGEEGEGEGEEE-EGEEEGEEREKEGEGEENRRNREEE-EEEEGKYQETG 1073 Query: 132 EEE----DGEGF--------SFKYSPGKLRGNQYKKMMTKEELEEEQRTE 169 EEE DGE + S KY GK + Q K + + +EQR++ Sbjct: 1074 EEENERQDGEEYKKVSKIKGSVKY--GKHKTYQKKSVTNTQGNGKEQRSK 1121 Score = 30.4 bits (67), Expect = 0.77 Identities = 33/117 (28%), Positives = 47/117 (40%), Gaps = 24/117 (20%) Query: 73 EPGEP-AGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQE---------------- 115 E GE G GE+ P G GE E + EEQ + R++ Sbjct: 675 EKGEKDKGRGEMERP-GEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEE 733 Query: 116 -----EEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMT-KEELEEEQ 166 EE++ D E+ EG +E+GEG + K G + K+ KEE EE+ Sbjct: 734 EHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE 790 Score = 28.9 bits (63), Expect = 2.2 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 4/71 (5%) Query: 104 EAEEQAVEARQEEEQDLDGEK---GPSSEGP-EEEDGEGFSFKYSPGKLRGNQYKKMMTK 159 E EE+ + +EEE++ +G++ G EG E+E+GE + + + +G + Sbjct: 737 EGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEG 796 Query: 160 EELEEEQRTEE 170 EE E E R EE Sbjct: 797 EEEETEGRGEE 807 >gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] Length = 2217 Score = 52.8 bits (125), Expect = 1e-07 Identities = 46/129 (35%), Positives = 52/129 (40%), Gaps = 25/129 (19%) Query: 30 GAAASPEPARAPPEP--------APPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLG 81 G A+ P PP+P A RP AP PAA A P PG PA G Sbjct: 56 GLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAG 115 Query: 82 ELGEPAGPGEPEGPGDPAAAPAEA---------EEQAVEARQEEEQDLDGEKGPS----S 128 EP G EP GP DP AA E EE A R+E+E + + P Sbjct: 116 P--EPVGTQEP-GP-DPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRD 171 Query: 129 EGPEEEDGE 137 E EEED E Sbjct: 172 EPEEEEDDE 180 Score = 40.8 bits (94), Expect = 6e-04 Identities = 38/108 (35%), Positives = 49/108 (45%), Gaps = 16/108 (14%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG 88 RG A+P PA +P P GAPA PE P G +EPG P + E A Sbjct: 90 RGRPAAPAPAALVAQPGAP----GAPAD---AGPE----PVGTQEPG-PDPIAAAVETA- 136 Query: 89 PGEPEGPGDPAAAPAEAEEQ-AVEARQEEEQDLDGEKGPSSEGPEEED 135 P GP + AAA E++ A EA+ E + E P E +E+D Sbjct: 137 PAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDE--PEEEEDDEDD 182 Score = 40.8 bits (94), Expect = 6e-04 Identities = 30/100 (30%), Positives = 38/100 (38%), Gaps = 1/100 (1%) Query: 27 VRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86 V+ A P+PA PP+P P + P P+ P P P P +P P +P Sbjct: 932 VQNMRATPPQPA-LPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQP 990 Query: 87 AGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGP 126 P +P P P EQA A Q L G P Sbjct: 991 VLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAP 1030 Score = 38.9 bits (89), Expect = 0.002 Identities = 50/187 (26%), Positives = 64/187 (34%), Gaps = 34/187 (18%) Query: 1 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60 M P +L PAL L L + AA+P PAP A A P+ P Sbjct: 985 MLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPV 1044 Query: 61 APEPAASPAGPEE---------PGEPAGLGELG--------------EPAGPGEPEGPGD 97 P SP PE P P+ L + PA P P GPG Sbjct: 1045 PPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPG- 1103 Query: 98 PAAAPAEAEEQAVEARQEEEQDLDGEKG-----PSSEGPEEEDGEGFSFK----YSPGKL 148 A+P + VE QEE+ D G S G + G+ S + G+L Sbjct: 1104 -IASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTSGKELSDSCEGAFGGGRL 1162 Query: 149 RGNQYKK 155 G +K Sbjct: 1163 EGRAARK 1169 Score = 37.0 bits (84), Expect = 0.008 Identities = 29/75 (38%), Positives = 34/75 (45%), Gaps = 6/75 (8%) Query: 29 RGAAASPEPARAP-PEPAP----PAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGEL 83 R A+A EP P PEP+P P A G PAP P A A S A + P P G Sbjct: 1466 RDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAA-VGAVSLATSQLPSPPLGPTVP 1524 Query: 84 GEPAGPGEPEGPGDP 98 +P E +G G P Sbjct: 1525 PQPPSALESDGEGPP 1539 Score = 35.4 bits (80), Expect = 0.024 Identities = 28/76 (36%), Positives = 30/76 (39%), Gaps = 6/76 (7%) Query: 32 AASPEPARAPPEPAPPAEATGAPAPS-RPCAPEPAASPAGPEEPGEPAGLGELGEPAGPG 90 AAS A AP EP PP AP PS P+PA P P G L P Sbjct: 1462 AASTRDASAPREPLPPP----APEPSPHSGTPQPALGQPAPLLPA-AVGAVSLATSQLPS 1516 Query: 91 EPEGPGDPAAAPAEAE 106 P GP P P+ E Sbjct: 1517 PPLGPTVPPQPPSALE 1532 Score = 33.9 bits (76), Expect = 0.069 Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 8/63 (12%) Query: 32 AASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE 91 A P APP P P+ +P P+ A+PA P EPA G + GPG Sbjct: 1371 AGPSNPPGAPPAPLAPS------SPPVTALPQDGAAPATSTMP-EPAS-GTASQAGGPGT 1422 Query: 92 PEG 94 P+G Sbjct: 1423 PQG 1425 Score = 29.6 bits (65), Expect = 1.3 Identities = 20/66 (30%), Positives = 23/66 (34%) Query: 37 PARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPG 96 P A P P P A P +P P A + G PA L L P P +P Sbjct: 732 PPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQV 791 Query: 97 DPAAAP 102 P P Sbjct: 792 PPQMPP 797 Score = 29.6 bits (65), Expect = 1.3 Identities = 29/116 (25%), Positives = 41/116 (35%), Gaps = 18/116 (15%) Query: 24 WLLVRRGAAASPEPARAPPEPAPPAEATG-APAPSRPCAP--EPAASPAGPEEPGEPAGL 80 W ++ + PA PE +PP + P S+ AP + +S P L Sbjct: 1312 WFII---CPVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLL 1368 Query: 81 GELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG 136 + G PG P P P++ P A Q DG +S PE G Sbjct: 1369 SQAGPSNPPGAPPAPLAPSSPPVTALPQ------------DGAAPATSTMPEPASG 1412 Score = 29.3 bits (64), Expect = 1.7 Identities = 18/60 (30%), Positives = 23/60 (38%), Gaps = 6/60 (10%) Query: 73 EPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPE 132 EPG AG PAG EP VE+ QEE L+ + P + P+ Sbjct: 16 EPGRGAG------PAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQ 69 >gi|23503317 coiled-coil domain containing 96 [Homo sapiens] Length = 555 Score = 52.0 bits (123), Expect = 2e-07 Identities = 48/150 (32%), Positives = 69/150 (46%), Gaps = 26/150 (17%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89 G PA PEP PAE GA P++P EP A GPEE AG EL + A Sbjct: 83 GPGEPGRPAEPQPEPEEPAEV-GAEEPAQP---EPGA---GPEELEAEAGAEELEQAAEG 135 Query: 90 GEPEGPG---------DPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFS 140 E + AAA EAE + VE +E++++ + S +E DGEG Sbjct: 136 KEVRFQASLPLTRIDEEEAAAAPEAETERVEGEEEDKEETQRDGAES----KERDGEG-- 189 Query: 141 FKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170 P K + + K++ ++E E+ + +EE Sbjct: 190 ---RPAKSQ-EEGKRLYGRDEFEDLEWSEE 215 Score = 41.2 bits (95), Expect = 4e-04 Identities = 31/107 (28%), Positives = 37/107 (34%), Gaps = 5/107 (4%) Query: 32 AASPEPARA---PPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGL--GELGEP 86 AA P +A PP P E P A E+ P GL E Sbjct: 22 AARPSKIKASSGPPTSPEPGELESEPEEEEEEQAASQGGTAADEQAEAPKGLTAAEAAGE 81 Query: 87 AGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEE 133 GPGEP P +P P E E E + E E+ + G EE Sbjct: 82 EGPGEPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELEAEAGAEE 128 Score = 40.4 bits (93), Expect = 7e-04 Identities = 43/142 (30%), Positives = 56/142 (39%), Gaps = 6/142 (4%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89 G SPEP EP E A + A E A +P G E AG GEP P Sbjct: 33 GPPTSPEPGELESEPEEEEEEQAA-SQGGTAADEQAEAPKGLTA-AEAAGEEGPGEPGRP 90 Query: 90 GEPE-GPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKL 148 EP+ P +PA AE Q EE L+ E G + E + +G+ F+ S Sbjct: 91 AEPQPEPEEPAEVGAEEPAQPEPGAGPEE--LEAEAG-AEELEQAAEGKEVRFQASLPLT 147 Query: 149 RGNQYKKMMTKEELEEEQRTEE 170 R ++ + E E EE Sbjct: 148 RIDEEEAAAAPEAETERVEGEE 169 Score = 28.9 bits (63), Expect = 2.2 Identities = 32/119 (26%), Positives = 41/119 (34%), Gaps = 5/119 (4%) Query: 52 GAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVE 111 G S P + +GP EP GEL + P E E + A+EQA Sbjct: 15 GGDGESLAARPSKIKASSGPPTSPEP---GEL--ESEPEEEEEEQAASQGGTAADEQAEA 69 Query: 112 ARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170 + + GE+GP G E G Q + EELE E EE Sbjct: 70 PKGLTAAEAAGEEGPGEPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELEAEAGAEE 128 >gi|156071470 hyperpolarization activated cyclic nucleotide-gated potassium channel 2 [Homo sapiens] Length = 889 Score = 51.6 bits (122), Expect = 3e-07 Identities = 39/117 (33%), Positives = 47/117 (40%), Gaps = 15/117 (12%) Query: 28 RRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87 R G + PA PP P PPA P P P AP P PA P+ P L E A Sbjct: 9 RPGESPGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEALPP--EAA 66 Query: 88 GPGEPEG-----------PGDP-AAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPE 132 G P G PG P AA+ A+ R E + G +GP + GP+ Sbjct: 67 DEGGPRGRLRSRDSSCGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGP-ARGPK 122 Score = 42.4 bits (98), Expect = 2e-04 Identities = 35/88 (39%), Positives = 37/88 (42%), Gaps = 11/88 (12%) Query: 26 LVRRGAAASPEPARAPPEPAPPAEATGAPAPSR-----PCAPEPAASPAGPEEPGEPAGL 80 LVRR P PA A P P PPA GAPA R P PAA AGP P L Sbjct: 757 LVRR-PPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPAR--RL 813 Query: 81 GELGEP---AGPGEPEGPGDPAAAPAEA 105 P + P P G PAA+ A Sbjct: 814 SRASRPLSASQPSLPHGAPGPAASTRPA 841 Score = 39.3 bits (90), Expect = 0.002 Identities = 35/100 (35%), Positives = 43/100 (43%), Gaps = 13/100 (13%) Query: 4 PAELLAALPALATALALL----LAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRP 59 P ++ +A+ L A A+ +A LV A SP R PP P P APA + P Sbjct: 720 PPQVTSAIATLQQAAAMSFCPQVARPLVGPLALGSPRLVRRPP-PGP------APAAASP 772 Query: 60 CAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPA 99 P PA+ P P P P G PA P GP PA Sbjct: 773 GPPPPASPPGAPASPRAPRTSPYGGLPAAP--LAGPALPA 810 Score = 37.0 bits (84), Expect = 0.008 Identities = 31/98 (31%), Positives = 39/98 (39%), Gaps = 13/98 (13%) Query: 47 PAEATGA-PAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPG--EPEGPGDPAAAPA 103 P E+ GA PAP P P PA P P PA P GPG P+ P A P Sbjct: 10 PGESPGATPAPGPPPPPPPAPPQQQPPPPPPPA------PPPGPGPAPPQHPPRAEALPP 63 Query: 104 EAEEQAVEARQEEEQDLD----GEKGPSSEGPEEEDGE 137 EA ++ + +D G G +S +GE Sbjct: 64 EAADEGGPRGRLRSRDSSCGRPGTPGAASTAKGSPNGE 101 Score = 36.2 bits (82), Expect = 0.014 Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 1/81 (1%) Query: 46 PPAEATGAPAPSRPCAP-EPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAE 104 P A +T +P+ C EP SPAGPE P + A G GPG A +E Sbjct: 88 PGAASTAKGSPNGECGRGEPQCSPAGPEGPARGPKVSFSCRGAASGPAPGPGPAEEAGSE 147 Query: 105 AEEQAVEARQEEEQDLDGEKG 125 A E R + + + G Sbjct: 148 EAGPAGEPRGSQASFMQRQFG 168 Score = 34.3 bits (77), Expect = 0.053 Identities = 31/98 (31%), Positives = 38/98 (38%), Gaps = 17/98 (17%) Query: 12 PALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGP 71 P + +A+A L ++ AA S P A P P A + P P PAA+ GP Sbjct: 721 PQVTSAIATL------QQAAAMSFCPQVARPLVGPLALGSPRLVRRPPPGPAPAAASPGP 774 Query: 72 EEPGEPAGLGELGEPAGPGEPEG------PGDPAAAPA 103 P P G PA P P P P A PA Sbjct: 775 PPPASPP-----GAPASPRAPRTSPYGGLPAAPLAGPA 807 Score = 31.2 bits (69), Expect = 0.45 Identities = 23/66 (34%), Positives = 24/66 (36%), Gaps = 9/66 (13%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89 G EP +P P PA R A PA P EE G E AGP Sbjct: 100 GECGRGEPQCSPAGPEGPARGPKVSFSCRGAASGPAPGPGPAEEAG--------SEEAGP 151 Query: 90 -GEPEG 94 GEP G Sbjct: 152 AGEPRG 157 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 51.2 bits (121), Expect = 4e-07 Identities = 42/128 (32%), Positives = 51/128 (39%), Gaps = 22/128 (17%) Query: 30 GAAASPEPARAPPEPAPP--------------AEATGAPAPSRPCAPEPAASPAGPE-EP 74 G SP PA A P A A G P P P P+ A P GP+ + Sbjct: 396 GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT 455 Query: 75 GEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL-----DGEKG-PSS 128 GEP G GE GEP GP P AP A E+ + E + GE+G P + Sbjct: 456 GEPGIAGFKGEQGPKGEP-GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGN 514 Query: 129 EGPEEEDG 136 G +DG Sbjct: 515 RGFPGQDG 522 Score = 44.7 bits (104), Expect = 4e-05 Identities = 38/113 (33%), Positives = 46/113 (40%), Gaps = 11/113 (9%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGEPAG 88 GAA P + P PP G P PS P+ A +GP GEP G G P Sbjct: 900 GAAGRVGPPGSNGNPGPP----GPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGE 955 Query: 89 PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137 GEP G P+ A Q + A Q L G++G P GP E G+ Sbjct: 956 KGEP-GDDGPSGAEGPPGPQGL-AGQRGIVGLPGQRGERGFPGLPGPSGEPGK 1006 Score = 43.9 bits (102), Expect = 7e-05 Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 13/104 (12%) Query: 44 PAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD--PAAA 101 P P G P P+ AP P P EPGEP G +G PG P PGD A Sbjct: 202 PMGPMGPRGPPGPAG--APGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGK 259 Query: 102 PAEAEEQAVEARQEEE-----QDLDGEKG----PSSEGPEEEDG 136 P +A E+ Q L G KG P +G + E G Sbjct: 260 PGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAG 303 Score = 42.7 bits (99), Expect = 1e-04 Identities = 40/149 (26%), Positives = 50/149 (33%), Gaps = 42/149 (28%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPA-------------------------PSRPCAPE 63 RG P PA PP P PA G P P P +P Sbjct: 344 RGNDGQPGPA-GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPG 402 Query: 64 PAASPAGPEEPGEPAGLGELGEPA-----------GPGEPEGPGDPAAAPAEAEEQAVEA 112 PA + P G P G G P GP P+G P + E + A Sbjct: 403 PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI-A 461 Query: 113 RQEEEQDLDGEKGPS----SEGPEEEDGE 137 + EQ GE GP+ + GP E+G+ Sbjct: 462 GFKGEQGPKGEPGPAGPQGAPGPAGEEGK 490 Score = 42.4 bits (98), Expect = 2e-04 Identities = 35/116 (30%), Positives = 43/116 (37%), Gaps = 9/116 (7%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPE------PAASPAGPEEPGEPAGLGE 82 +G +P P EP P G P P P P A G +E A LG Sbjct: 140 KGEKGAPGPRGRDGEPGTPGNP-GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 198 Query: 83 LGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGP-SSEGPEEEDGE 137 + P GP P GP PA AP Q + E + G GP GP + G+ Sbjct: 199 MQGPMGPMGPRGPPGPAGAPGPQGFQG-NPGEPGEPGVSGPMGPRGPPGPPGKPGD 253 Score = 42.0 bits (97), Expect = 3e-04 Identities = 37/126 (29%), Positives = 45/126 (35%), Gaps = 12/126 (9%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRP---CAPEPAASPAGPE-EPGEPAGLGELG 84 +G A A AP P +GAP P P P+ A GP G P G +G Sbjct: 851 QGEAGQKGDAGAPGPQGP----SGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVG 906 Query: 85 EPAGPGEPEGPGDPAAA----PAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFS 140 P G P PG P + P A + + E L G GP E E D Sbjct: 907 PPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSG 966 Query: 141 FKYSPG 146 + PG Sbjct: 967 AEGPPG 972 Score = 40.8 bits (94), Expect = 6e-04 Identities = 32/105 (30%), Positives = 37/105 (35%), Gaps = 6/105 (5%) Query: 39 RAPPEPAPPAEATG-APAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD 97 R PP P P TG A P R +P P G GE G PG P PG Sbjct: 1016 RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1075 Query: 98 PA-AAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137 P A P + EA + G G +GP + GE Sbjct: 1076 PGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGE 1120 Score = 40.4 bits (93), Expect = 7e-04 Identities = 32/103 (31%), Positives = 39/103 (37%), Gaps = 11/103 (10%) Query: 38 ARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD 97 A PP PA PA G AP P+ P PG P G+ G+ PGE PG Sbjct: 640 AAGPPGPAGPAGERGEQG-----APGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPG- 693 Query: 98 PAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDG 136 P E Q L G +G P ++GP+ G Sbjct: 694 -LVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG 735 Score = 39.3 bits (90), Expect = 0.002 Identities = 42/126 (33%), Positives = 49/126 (38%), Gaps = 19/126 (15%) Query: 29 RGAA--ASPEPARAP-----PEPAPPAEA----TGAPAPSRPCAPEPAASPAGPEEPGEP 77 RGAA A P+ R PE AP + TG P P GP P Sbjct: 755 RGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGS 814 Query: 78 AGL----GELGE--PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPS-SEG 130 AG GE GE P GP GP P EQ EA Q+ + G +GPS + G Sbjct: 815 AGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQG-EAGQKGDAGAPGPQGPSGAPG 873 Query: 131 PEEEDG 136 P+ G Sbjct: 874 PQGPTG 879 Score = 39.3 bits (90), Expect = 0.002 Identities = 33/124 (26%), Positives = 40/124 (32%), Gaps = 17/124 (13%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89 G A P +P PP A +P P PG P G G+ Sbjct: 1029 GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1088 Query: 90 GE-----PEGPGDPAAA-----PAEAEEQAVEARQEEEQDLDGEKG-------PSSEGPE 132 GE P GP PA A P EA + E+ L G +G P GP Sbjct: 1089 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS 1148 Query: 133 EEDG 136 + G Sbjct: 1149 GDQG 1152 Score = 39.3 bits (90), Expect = 0.002 Identities = 25/68 (36%), Positives = 27/68 (39%), Gaps = 11/68 (16%) Query: 33 ASPEPARAPPEPAPPAE---ATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGEPAG 88 A P R PP P P+ A G P P P P + GP PG P P G Sbjct: 1157 AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG-------PPG 1209 Query: 89 PGEPEGPG 96 P P GPG Sbjct: 1210 PPGPPGPG 1217 Score = 38.9 bits (89), Expect = 0.002 Identities = 43/144 (29%), Positives = 53/144 (36%), Gaps = 50/144 (34%) Query: 29 RGAAASPEPARAPPEPAP-----PAEATGAPAPSR---------------------PCAP 62 +G+A +P A AP P P P ATG P P P Sbjct: 419 KGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP 478 Query: 63 EPAASPAGPEEP----GEPAGLGELG---EPAGPGEPEGPG-DPAAAPAEAEEQAVEARQ 114 + A PAG E GEP G+G +G E PG PG D A P A Sbjct: 479 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGA--------- 529 Query: 115 EEEQDLDGEKGPSS-EGPEEEDGE 137 GE+GPS GP+ +G+ Sbjct: 530 ------PGERGPSGLAGPKGANGD 547 Score = 38.5 bits (88), Expect = 0.003 Identities = 30/101 (29%), Positives = 37/101 (36%), Gaps = 19/101 (18%) Query: 41 PPEPAPPAEATGAPAPSRPCAPEPAASPAG-------PEEPGEPAGLGELGE--PAGPGE 91 PP P+ A+G PS P P P+G P G P G GE PAGP Sbjct: 1144 PPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPG 1203 Query: 92 PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPE 132 GP P P + + A GP +GP+ Sbjct: 1204 NPGPPGPPGPPGPGIDMSAFA----------GLGPREKGPD 1234 Score = 37.0 bits (84), Expect = 0.008 Identities = 41/122 (33%), Positives = 46/122 (37%), Gaps = 23/122 (18%) Query: 35 PEPARAPPEPAPPAEATGAPAPS----RPCAP-EPAAS-PAGPE-EPGEPAGLGELGEPA 87 P R PP PA GAP P P P EP S P GP PG P G+ GE Sbjct: 205 PMGPRGPPGPA------GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 258 Query: 88 GPGE-----PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGEG 138 PG+ P GP P V+ + LDG KG P +G GE Sbjct: 259 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHR-GYPGLDGAKGEAGAPGVKGESGSPGEN 317 Query: 139 FS 140 S Sbjct: 318 GS 319 Score = 37.0 bits (84), Expect = 0.008 Identities = 22/70 (31%), Positives = 24/70 (34%), Gaps = 13/70 (18%) Query: 42 PEPAPPAEATGAPAPSRPCAPEPAASPAGPE-------------EPGEPAGLGELGEPAG 88 P P P+ GA P+ P P P GP PG GE G Sbjct: 1142 PGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP 1201 Query: 89 PGEPEGPGDP 98 PG P PG P Sbjct: 1202 PGNPGPPGPP 1211 Score = 35.8 bits (81), Expect = 0.018 Identities = 21/69 (30%), Positives = 24/69 (34%), Gaps = 1/69 (1%) Query: 31 AAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGEPAGP 89 A+ P P EP + G P P P P G + GE G G P Sbjct: 96 ASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155 Query: 90 GEPEGPGDP 98 G P PG P Sbjct: 156 GTPGNPGPP 164 Score = 35.8 bits (81), Expect = 0.018 Identities = 37/134 (27%), Positives = 46/134 (34%), Gaps = 39/134 (29%) Query: 28 RRGAAASPEPARAPPEPAP-----------------PAEATGAPAPSRPCAPEPAASPAG 70 ++G A +P P P P P ATG P + P + G Sbjct: 856 QKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPG 915 Query: 71 PEEPGEPAG-------LGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGE 123 P P P+G G+ G P GEP G PA P E E G+ Sbjct: 916 PPGPPGPSGKDGPKGARGDSGPPGRAGEP-GLQGPAGPPGEKGE-------------PGD 961 Query: 124 KGPS-SEGPEEEDG 136 GPS +EGP G Sbjct: 962 DGPSGAEGPPGPQG 975 Score = 35.4 bits (80), Expect = 0.024 Identities = 35/112 (31%), Positives = 40/112 (35%), Gaps = 14/112 (12%) Query: 30 GAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87 G P P A EP E GAP + AGP P PAG E GE Sbjct: 600 GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG--ERGEQG 657 Query: 88 GPGEP--EGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDG 136 PG +G P P E + +Q + GE G P GP E G Sbjct: 658 APGPSGFQGLPGPPGPPGEGGKPG-------DQGVPGEAGAPGLVGPRGERG 702 Score = 34.7 bits (78), Expect = 0.041 Identities = 34/143 (23%), Positives = 45/143 (31%), Gaps = 28/143 (19%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE--- 85 RG +P P+ P PP P P A +P GE GE G Sbjct: 653 RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA 712 Query: 86 -----------------------PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDG 122 PAGP +GP P E + + + D+ G Sbjct: 713 QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV-G 771 Query: 123 EKGPSSEGPEEEDGEGFSFKYSP 145 EKGP P ++ G G + P Sbjct: 772 EKGPEG-APGKDGGRGLTGPIGP 793 Score = 34.3 bits (77), Expect = 0.053 Identities = 34/114 (29%), Positives = 38/114 (33%), Gaps = 21/114 (18%) Query: 45 APPAEATGAPAPSRPCAPEPA-ASPAGPEEPGEPAGLGELGEPA------------GPGE 91 A P A G PS P+ A P P EPG P G G P PGE Sbjct: 524 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE 583 Query: 92 PEGPGDPAAAPAEAEEQAV----EARQEEEQDLDGEKG----PSSEGPEEEDGE 137 PG P A + + E GEKG P G +DGE Sbjct: 584 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 637 Score = 33.9 bits (76), Expect = 0.069 Identities = 37/122 (30%), Positives = 41/122 (33%), Gaps = 17/122 (13%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPE-PAASPAGPEEPGEPAGLGELGE--- 85 G A +P P P P E G P P P P P E G+P GE G Sbjct: 213 GPAGAPGPQGFQGNPGEPGEP-GVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGP 271 Query: 86 ------PAGPGEPEGPGD---PAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEED 135 P PG P G P A+ E A + E GE G P GP Sbjct: 272 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS--PGENGSPGPMGPRGLP 329 Query: 136 GE 137 GE Sbjct: 330 GE 331 Score = 33.9 bits (76), Expect = 0.069 Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 1/48 (2%) Query: 52 GAPAPSRPCAPEPAASPAGPEEP-GEPAGLGELGEPAGPGEPEGPGDP 98 G P P P + A+ PAGP P G P +G G+ G P G P Sbjct: 1140 GLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP 1187 Score = 33.1 bits (74), Expect = 0.12 Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 19/83 (22%) Query: 59 PCAPEPAASPAGPEEP----GEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQ 114 P P A+ +G P GEP + ++ P GP P+GP A EQ + Sbjct: 87 PICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGP---------AGEQGPRGDR 137 Query: 115 EEEQDLDGEKGPSSEGPEEEDGE 137 ++ GEKG + GP DGE Sbjct: 138 GDK----GEKG--APGPRGRDGE 154 Score = 32.7 bits (73), Expect = 0.15 Identities = 36/118 (30%), Positives = 45/118 (38%), Gaps = 14/118 (11%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAP-----EPAAS-PAGPEEPGEPAGL--- 80 G + P A + PP A G P P P EP P+G E P P GL Sbjct: 921 GPSGKDGPKGARGDSGPPGRA-GEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 979 Query: 81 -GELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDG 136 G +G P GE PG P + ++ A A ++ G GP GP E G Sbjct: 980 RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA--SGDRGPPGPVGPPGLTGPAGEPG 1035 Score = 32.3 bits (72), Expect = 0.20 Identities = 34/122 (27%), Positives = 40/122 (32%), Gaps = 14/122 (11%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG 88 +G P A E P + +P +P P P E G G G Sbjct: 287 KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN 346 Query: 89 PGEPE------------GPGDPAAAPAEAEEQAVEAR-QEEEQDLDGEKG-PSSEGPEEE 134 G+P GPG P A A+ E AR E Q GE G P S GP Sbjct: 347 DGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA 406 Query: 135 DG 136 G Sbjct: 407 SG 408 Score = 32.0 bits (71), Expect = 0.26 Identities = 39/135 (28%), Positives = 46/135 (34%), Gaps = 29/135 (21%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASP-----------------AGP 71 +G P PA P P E A P P P AGP Sbjct: 467 QGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGP 526 Query: 72 E-EPGE--PAGL-GELGEPAGPGEPEGPGDPAA-----APAEAEEQAVEARQEEEQDLDG 122 + PGE P+GL G G PG P PG P A P +A Q + DG Sbjct: 527 KGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQG-KVGPSGAPGEDG 585 Query: 123 EKGPSSEGPEEEDGE 137 GP GP+ G+ Sbjct: 586 RPGP--PGPQGARGQ 598 Score = 32.0 bits (71), Expect = 0.26 Identities = 43/155 (27%), Positives = 48/155 (30%), Gaps = 47/155 (30%) Query: 30 GAAASPEPARA--------PPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGL 80 G P PA A PP PA A A GAP P A AGP G+P Sbjct: 789 GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 848 Query: 81 GELGE--------------PAGPGEPEGP-------------------GDPAAA----PA 103 GE GE P+G P+GP G P AA P Sbjct: 849 GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 908 Query: 104 EAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGE 137 + DG KG + GP GE Sbjct: 909 GSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 943 Score = 31.6 bits (70), Expect = 0.34 Identities = 36/122 (29%), Positives = 41/122 (33%), Gaps = 9/122 (7%) Query: 30 GAAASPEPA--RAPPEPAPPAEATGAPA-PSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86 G A P A R PP P A G P P P P GE G GE Sbjct: 255 GEAGKPGKAGERGPPGPQG---ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 311 Query: 87 AGPGEPEGPG--DPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYS 144 PGE PG P P E + A + DG+ GP+ G F + Sbjct: 312 GSPGENGSPGPMGPRGLPGE-RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGA 370 Query: 145 PG 146 PG Sbjct: 371 PG 372 Score = 31.2 bits (69), Expect = 0.45 Identities = 30/109 (27%), Positives = 36/109 (33%), Gaps = 5/109 (4%) Query: 33 ASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGE--PAGP 89 A P A+ PP GA + P GPE PG+ G G G P GP Sbjct: 737 AGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGP 796 Query: 90 GEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDGE 137 G P A E + G GP+ GP DG+ Sbjct: 797 AGANGEKGEVGPPGPAGSAGARGAPGERGE-TGPPGPAGFAGPPGADGQ 844 Score = 30.0 bits (66), Expect = 1.0 Identities = 34/121 (28%), Positives = 39/121 (32%), Gaps = 13/121 (10%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEE-PGEPAGLGELGEPA 87 RG P A P P+ A G P P+ A G PG GE G+ Sbjct: 560 RGLTGRPGDA-GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 618 Query: 88 GPGEPEGPG-------DPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDG 136 G P PG D A A A + EQ G G P GP E G Sbjct: 619 EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGG 678 Query: 137 E 137 + Sbjct: 679 K 679 Score = 29.6 bits (65), Expect = 1.3 Identities = 21/59 (35%), Positives = 22/59 (37%), Gaps = 8/59 (13%) Query: 41 PPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGL-GELGEPAGPGEPEGPGDP 98 P P P E AP A+ GP P P GL G GEP G P G P Sbjct: 995 PGLPGPSGEPGKQGAPG-------ASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 1046 Score = 29.6 bits (65), Expect = 1.3 Identities = 20/72 (27%), Positives = 21/72 (29%), Gaps = 25/72 (34%) Query: 52 GAPAPSRPCAPEPAASPAGPEEPGEPAG-------------------------LGELGEP 86 G P PS A P+GP P P G G G P Sbjct: 1143 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPP 1202 Query: 87 AGPGEPEGPGDP 98 PG P PG P Sbjct: 1203 GNPGPPGPPGPP 1214 Score = 29.3 bits (64), Expect = 1.7 Identities = 26/89 (29%), Positives = 32/89 (35%), Gaps = 11/89 (12%) Query: 52 GAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVE 111 G P PS + A +G P P G L PA GEP G P A + A Sbjct: 996 GLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA--GEPGREGSPGADGPPGRDGAAG 1053 Query: 112 ARQEEEQDLDGEKG----PSSEGPEEEDG 136 + + GE G P + GP G Sbjct: 1054 VKGDR-----GETGAVGAPGAPGPPGSPG 1077 Score = 29.3 bits (64), Expect = 1.7 Identities = 29/97 (29%), Positives = 33/97 (34%), Gaps = 11/97 (11%) Query: 42 PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAA 101 P P+ GAP S P P GP PG GE G PG PG AA Sbjct: 998 PGPSGEPGKQGAPGASGDRGPP---GPVGP--PGLTGPAGEPGREGSPGADGPPGRDGAA 1052 Query: 102 PAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDGE 137 + + A G G P S GP G+ Sbjct: 1053 GVKGDRGETGA-----VGAPGAPGPPGSPGPAGPTGK 1084 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 51.2 bits (121), Expect = 4e-07 Identities = 42/128 (32%), Positives = 51/128 (39%), Gaps = 22/128 (17%) Query: 30 GAAASPEPARAPPEPAPP--------------AEATGAPAPSRPCAPEPAASPAGPE-EP 74 G SP PA A P A A G P P P P+ A P GP+ + Sbjct: 327 GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT 386 Query: 75 GEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL-----DGEKG-PSS 128 GEP G GE GEP GP P AP A E+ + E + GE+G P + Sbjct: 387 GEPGIAGFKGEQGPKGEP-GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGN 445 Query: 129 EGPEEEDG 136 G +DG Sbjct: 446 RGFPGQDG 453 Score = 44.7 bits (104), Expect = 4e-05 Identities = 38/113 (33%), Positives = 46/113 (40%), Gaps = 11/113 (9%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGEPAG 88 GAA P + P PP G P PS P+ A +GP GEP G G P Sbjct: 831 GAAGRVGPPGSNGNPGPP----GPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGE 886 Query: 89 PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137 GEP G P+ A Q + A Q L G++G P GP E G+ Sbjct: 887 KGEP-GDDGPSGAEGPPGPQGL-AGQRGIVGLPGQRGERGFPGLPGPSGEPGK 937 Score = 43.9 bits (102), Expect = 7e-05 Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 13/104 (12%) Query: 44 PAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD--PAAA 101 P P G P P+ AP P P EPGEP G +G PG P PGD A Sbjct: 133 PMGPMGPRGPPGPAG--APGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGK 190 Query: 102 PAEAEEQAVEARQEEE-----QDLDGEKG----PSSEGPEEEDG 136 P +A E+ Q L G KG P +G + E G Sbjct: 191 PGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAG 234 Score = 42.7 bits (99), Expect = 1e-04 Identities = 40/149 (26%), Positives = 50/149 (33%), Gaps = 42/149 (28%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPA-------------------------PSRPCAPE 63 RG P PA PP P PA G P P P +P Sbjct: 275 RGNDGQPGPA-GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPG 333 Query: 64 PAASPAGPEEPGEPAGLGELGEPA-----------GPGEPEGPGDPAAAPAEAEEQAVEA 112 PA + P G P G G P GP P+G P + E + A Sbjct: 334 PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI-A 392 Query: 113 RQEEEQDLDGEKGPS----SEGPEEEDGE 137 + EQ GE GP+ + GP E+G+ Sbjct: 393 GFKGEQGPKGEPGPAGPQGAPGPAGEEGK 421 Score = 42.4 bits (98), Expect = 2e-04 Identities = 35/116 (30%), Positives = 43/116 (37%), Gaps = 9/116 (7%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPE------PAASPAGPEEPGEPAGLGE 82 +G +P P EP P G P P P P A G +E A LG Sbjct: 71 KGEKGAPGPRGRDGEPGTPGNP-GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 129 Query: 83 LGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGP-SSEGPEEEDGE 137 + P GP P GP PA AP Q + E + G GP GP + G+ Sbjct: 130 MQGPMGPMGPRGPPGPAGAPGPQGFQG-NPGEPGEPGVSGPMGPRGPPGPPGKPGD 184 Score = 42.0 bits (97), Expect = 3e-04 Identities = 30/92 (32%), Positives = 34/92 (36%), Gaps = 5/92 (5%) Query: 12 PALATALALLLAWLLVRRGA-AASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAG 70 P L LL+A +L +G P P EP + G P P P P G Sbjct: 7 PQTLVLLTLLVAAVLRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRG 66 Query: 71 PE----EPGEPAGLGELGEPAGPGEPEGPGDP 98 E G P G GEP PG P PG P Sbjct: 67 DRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPP 98 Score = 42.0 bits (97), Expect = 3e-04 Identities = 37/126 (29%), Positives = 45/126 (35%), Gaps = 12/126 (9%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRP---CAPEPAASPAGPE-EPGEPAGLGELG 84 +G A A AP P +GAP P P P+ A GP G P G +G Sbjct: 782 QGEAGQKGDAGAPGPQGP----SGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVG 837 Query: 85 EPAGPGEPEGPGDPAAA----PAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFS 140 P G P PG P + P A + + E L G GP E E D Sbjct: 838 PPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSG 897 Query: 141 FKYSPG 146 + PG Sbjct: 898 AEGPPG 903 Score = 40.8 bits (94), Expect = 6e-04 Identities = 32/105 (30%), Positives = 37/105 (35%), Gaps = 6/105 (5%) Query: 39 RAPPEPAPPAEATG-APAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD 97 R PP P P TG A P R +P P G GE G PG P PG Sbjct: 947 RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1006 Query: 98 PA-AAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137 P A P + EA + G G +GP + GE Sbjct: 1007 PGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGE 1051 Score = 40.4 bits (93), Expect = 7e-04 Identities = 32/103 (31%), Positives = 39/103 (37%), Gaps = 11/103 (10%) Query: 38 ARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD 97 A PP PA PA G AP P+ P PG P G+ G+ PGE PG Sbjct: 571 AAGPPGPAGPAGERGEQG-----APGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPG- 624 Query: 98 PAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDG 136 P E Q L G +G P ++GP+ G Sbjct: 625 -LVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG 666 Score = 39.3 bits (90), Expect = 0.002 Identities = 42/126 (33%), Positives = 49/126 (38%), Gaps = 19/126 (15%) Query: 29 RGAA--ASPEPARAP-----PEPAPPAEA----TGAPAPSRPCAPEPAASPAGPEEPGEP 77 RGAA A P+ R PE AP + TG P P GP P Sbjct: 686 RGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGS 745 Query: 78 AGL----GELGE--PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPS-SEG 130 AG GE GE P GP GP P EQ EA Q+ + G +GPS + G Sbjct: 746 AGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQG-EAGQKGDAGAPGPQGPSGAPG 804 Query: 131 PEEEDG 136 P+ G Sbjct: 805 PQGPTG 810 Score = 39.3 bits (90), Expect = 0.002 Identities = 33/124 (26%), Positives = 40/124 (32%), Gaps = 17/124 (13%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89 G A P +P PP A +P P PG P G G+ Sbjct: 960 GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1019 Query: 90 GE-----PEGPGDPAAA-----PAEAEEQAVEARQEEEQDLDGEKG-------PSSEGPE 132 GE P GP PA A P EA + E+ L G +G P GP Sbjct: 1020 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS 1079 Query: 133 EEDG 136 + G Sbjct: 1080 GDQG 1083 Score = 39.3 bits (90), Expect = 0.002 Identities = 25/68 (36%), Positives = 27/68 (39%), Gaps = 11/68 (16%) Query: 33 ASPEPARAPPEPAPPA---EATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGEPAG 88 A P R PP P P+ A G P P P P + GP PG P P G Sbjct: 1088 AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG-------PPG 1140 Query: 89 PGEPEGPG 96 P P GPG Sbjct: 1141 PPGPPGPG 1148 Score = 38.9 bits (89), Expect = 0.002 Identities = 43/144 (29%), Positives = 53/144 (36%), Gaps = 50/144 (34%) Query: 29 RGAAASPEPARAPPEPAP-----PAEATGAPAPSR---------------------PCAP 62 +G+A +P A AP P P P ATG P P P Sbjct: 350 KGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP 409 Query: 63 EPAASPAGPEEP----GEPAGLGELG---EPAGPGEPEGPG-DPAAAPAEAEEQAVEARQ 114 + A PAG E GEP G+G +G E PG PG D A P A Sbjct: 410 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGA--------- 460 Query: 115 EEEQDLDGEKGPSS-EGPEEEDGE 137 GE+GPS GP+ +G+ Sbjct: 461 ------PGERGPSGLAGPKGANGD 478 Score = 38.5 bits (88), Expect = 0.003 Identities = 30/101 (29%), Positives = 37/101 (36%), Gaps = 19/101 (18%) Query: 41 PPEPAPPAEATGAPAPSRPCAPEPAASPAG-------PEEPGEPAGLGELGE--PAGPGE 91 PP P+ A+G PS P P P+G P G P G GE PAGP Sbjct: 1075 PPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPG 1134 Query: 92 PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPE 132 GP P P + + A GP +GP+ Sbjct: 1135 NPGPPGPPGPPGPGIDMSAFA----------GLGPREKGPD 1165 Score = 37.0 bits (84), Expect = 0.008 Identities = 41/122 (33%), Positives = 46/122 (37%), Gaps = 23/122 (18%) Query: 35 PEPARAPPEPAPPAEATGAPAPS----RPCAP-EPAAS-PAGPE-EPGEPAGLGELGEPA 87 P R PP PA GAP P P P EP S P GP PG P G+ GE Sbjct: 136 PMGPRGPPGPA------GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 189 Query: 88 GPGE-----PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGEG 138 PG+ P GP P V+ + LDG KG P +G GE Sbjct: 190 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHR-GYPGLDGAKGEAGAPGVKGESGSPGEN 248 Query: 139 FS 140 S Sbjct: 249 GS 250 Score = 37.0 bits (84), Expect = 0.008 Identities = 22/70 (31%), Positives = 24/70 (34%), Gaps = 13/70 (18%) Query: 42 PEPAPPAEATGAPAPSRPCAPEPAASPAGPE-------------EPGEPAGLGELGEPAG 88 P P P+ GA P+ P P P GP PG GE G Sbjct: 1073 PGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP 1132 Query: 89 PGEPEGPGDP 98 PG P PG P Sbjct: 1133 PGNPGPPGPP 1142 Score = 35.8 bits (81), Expect = 0.018 Identities = 37/134 (27%), Positives = 46/134 (34%), Gaps = 39/134 (29%) Query: 28 RRGAAASPEPARAPPEPAP-----------------PAEATGAPAPSRPCAPEPAASPAG 70 ++G A +P P P P P ATG P + P + G Sbjct: 787 QKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPG 846 Query: 71 PEEPGEPAG-------LGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGE 123 P P P+G G+ G P GEP G PA P E E G+ Sbjct: 847 PPGPPGPSGKDGPKGARGDSGPPGRAGEP-GLQGPAGPPGEKGE-------------PGD 892 Query: 124 KGPS-SEGPEEEDG 136 GPS +EGP G Sbjct: 893 DGPSGAEGPPGPQG 906 Score = 35.4 bits (80), Expect = 0.024 Identities = 35/112 (31%), Positives = 40/112 (35%), Gaps = 14/112 (12%) Query: 30 GAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87 G P P A EP E GAP + AGP P PAG E GE Sbjct: 531 GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG--ERGEQG 588 Query: 88 GPGEP--EGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDG 136 PG +G P P E + +Q + GE G P GP E G Sbjct: 589 APGPSGFQGLPGPPGPPGEGGKPG-------DQGVPGEAGAPGLVGPRGERG 633 Score = 34.7 bits (78), Expect = 0.041 Identities = 34/143 (23%), Positives = 45/143 (31%), Gaps = 28/143 (19%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE--- 85 RG +P P+ P PP P P A +P GE GE G Sbjct: 584 RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA 643 Query: 86 -----------------------PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDG 122 PAGP +GP P E + + + D+ G Sbjct: 644 QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV-G 702 Query: 123 EKGPSSEGPEEEDGEGFSFKYSP 145 EKGP P ++ G G + P Sbjct: 703 EKGPEG-APGKDGGRGLTGPIGP 724 Score = 34.3 bits (77), Expect = 0.053 Identities = 34/114 (29%), Positives = 38/114 (33%), Gaps = 21/114 (18%) Query: 45 APPAEATGAPAPSRPCAPEPA-ASPAGPEEPGEPAGLGELGEPA------------GPGE 91 A P A G PS P+ A P P EPG P G G P PGE Sbjct: 455 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE 514 Query: 92 PEGPGDPAAAPAEAEEQAV----EARQEEEQDLDGEKG----PSSEGPEEEDGE 137 PG P A + + E GEKG P G +DGE Sbjct: 515 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 568 Score = 33.9 bits (76), Expect = 0.069 Identities = 37/122 (30%), Positives = 41/122 (33%), Gaps = 17/122 (13%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPE-PAASPAGPEEPGEPAGLGELGE--- 85 G A +P P P P E G P P P P P E G+P GE G Sbjct: 144 GPAGAPGPQGFQGNPGEPGEP-GVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGP 202 Query: 86 ------PAGPGEPEGPGD---PAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEED 135 P PG P G P A+ E A + E GE G P GP Sbjct: 203 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS--PGENGSPGPMGPRGLP 260 Query: 136 GE 137 GE Sbjct: 261 GE 262 Score = 33.9 bits (76), Expect = 0.069 Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 1/48 (2%) Query: 52 GAPAPSRPCAPEPAASPAGPEEP-GEPAGLGELGEPAGPGEPEGPGDP 98 G P P P + A+ PAGP P G P +G G+ G P G P Sbjct: 1071 GLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP 1118 Score = 33.1 bits (74), Expect = 0.12 Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 15/78 (19%) Query: 60 CAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQD 119 C + P + GEP + ++ P GP P+GP A EQ + ++ Sbjct: 23 CQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGP---------AGEQGPRGDRGDK-- 71 Query: 120 LDGEKGPSSEGPEEEDGE 137 GEKG + GP DGE Sbjct: 72 --GEKG--APGPRGRDGE 85 Score = 32.7 bits (73), Expect = 0.15 Identities = 36/118 (30%), Positives = 45/118 (38%), Gaps = 14/118 (11%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAP-----EPAAS-PAGPEEPGEPAGL--- 80 G + P A + PP A G P P P EP P+G E P P GL Sbjct: 852 GPSGKDGPKGARGDSGPPGRA-GEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 910 Query: 81 -GELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDG 136 G +G P GE PG P + ++ A A ++ G GP GP E G Sbjct: 911 RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA--SGDRGPPGPVGPPGLTGPAGEPG 966 Score = 32.3 bits (72), Expect = 0.20 Identities = 34/122 (27%), Positives = 40/122 (32%), Gaps = 14/122 (11%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG 88 +G P A E P + +P +P P P E G G G Sbjct: 218 KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN 277 Query: 89 PGEPE------------GPGDPAAAPAEAEEQAVEAR-QEEEQDLDGEKG-PSSEGPEEE 134 G+P GPG P A A+ E AR E Q GE G P S GP Sbjct: 278 DGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA 337 Query: 135 DG 136 G Sbjct: 338 SG 339 Score = 32.0 bits (71), Expect = 0.26 Identities = 39/135 (28%), Positives = 46/135 (34%), Gaps = 29/135 (21%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASP-----------------AGP 71 +G P PA P P E A P P P AGP Sbjct: 398 QGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGP 457 Query: 72 E-EPGE--PAGL-GELGEPAGPGEPEGPGDPAA-----APAEAEEQAVEARQEEEQDLDG 122 + PGE P+GL G G PG P PG P A P +A Q + DG Sbjct: 458 KGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQG-KVGPSGAPGEDG 516 Query: 123 EKGPSSEGPEEEDGE 137 GP GP+ G+ Sbjct: 517 RPGP--PGPQGARGQ 529 Score = 32.0 bits (71), Expect = 0.26 Identities = 43/155 (27%), Positives = 48/155 (30%), Gaps = 47/155 (30%) Query: 30 GAAASPEPARA--------PPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGL 80 G P PA A PP PA A A GAP P A AGP G+P Sbjct: 720 GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 779 Query: 81 GELGE--------------PAGPGEPEGP-------------------GDPAAA----PA 103 GE GE P+G P+GP G P AA P Sbjct: 780 GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 839 Query: 104 EAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGE 137 + DG KG + GP GE Sbjct: 840 GSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 874 Score = 31.6 bits (70), Expect = 0.34 Identities = 36/122 (29%), Positives = 41/122 (33%), Gaps = 9/122 (7%) Query: 30 GAAASPEPA--RAPPEPAPPAEATGAPA-PSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86 G A P A R PP P A G P P P P GE G GE Sbjct: 186 GEAGKPGKAGERGPPGPQG---ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 242 Query: 87 AGPGEPEGPG--DPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYS 144 PGE PG P P E + A + DG+ GP+ G F + Sbjct: 243 GSPGENGSPGPMGPRGLPGE-RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGA 301 Query: 145 PG 146 PG Sbjct: 302 PG 303 Score = 31.2 bits (69), Expect = 0.45 Identities = 30/109 (27%), Positives = 36/109 (33%), Gaps = 5/109 (4%) Query: 33 ASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGE--PAGP 89 A P A+ PP GA + P GPE PG+ G G G P GP Sbjct: 668 AGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGP 727 Query: 90 GEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDGE 137 G P A E + G GP+ GP DG+ Sbjct: 728 AGANGEKGEVGPPGPAGSAGARGAPGERGE-TGPPGPAGFAGPPGADGQ 775 Score = 30.0 bits (66), Expect = 1.0 Identities = 34/121 (28%), Positives = 39/121 (32%), Gaps = 13/121 (10%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEE-PGEPAGLGELGEPA 87 RG P A P P+ A G P P+ A G PG GE G+ Sbjct: 491 RGLTGRPGDA-GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 549 Query: 88 GPGEPEGPG-------DPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDG 136 G P PG D A A A + EQ G G P GP E G Sbjct: 550 EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGG 609 Query: 137 E 137 + Sbjct: 610 K 610 Score = 29.6 bits (65), Expect = 1.3 Identities = 21/59 (35%), Positives = 22/59 (37%), Gaps = 8/59 (13%) Query: 41 PPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGL-GELGEPAGPGEPEGPGDP 98 P P P E AP A+ GP P P GL G GEP G P G P Sbjct: 926 PGLPGPSGEPGKQGAPG-------ASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 977 Score = 29.6 bits (65), Expect = 1.3 Identities = 20/72 (27%), Positives = 21/72 (29%), Gaps = 25/72 (34%) Query: 52 GAPAPSRPCAPEPAASPAGPEEPGEPAG-------------------------LGELGEP 86 G P PS A P+GP P P G G G P Sbjct: 1074 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPP 1133 Query: 87 AGPGEPEGPGDP 98 PG P PG P Sbjct: 1134 GNPGPPGPPGPP 1145 Score = 29.3 bits (64), Expect = 1.7 Identities = 26/89 (29%), Positives = 32/89 (35%), Gaps = 11/89 (12%) Query: 52 GAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVE 111 G P PS + A +G P P G L PA GEP G P A + A Sbjct: 927 GLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA--GEPGREGSPGADGPPGRDGAAG 984 Query: 112 ARQEEEQDLDGEKG----PSSEGPEEEDG 136 + + GE G P + GP G Sbjct: 985 VKGDR-----GETGAVGAPGAPGPPGSPG 1008 Score = 29.3 bits (64), Expect = 1.7 Identities = 29/97 (29%), Positives = 33/97 (34%), Gaps = 11/97 (11%) Query: 42 PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAA 101 P P+ GAP S P P GP PG GE G PG PG AA Sbjct: 929 PGPSGEPGKQGAPGASGDRGPP---GPVGP--PGLTGPAGEPGREGSPGADGPPGRDGAA 983 Query: 102 PAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDGE 137 + + A G G P S GP G+ Sbjct: 984 GVKGDRGETGA-----VGAPGAPGPPGSPGPAGPTGK 1015 >gi|24308115 interferon regulatory factor 2 binding protein 1 [Homo sapiens] Length = 584 Score = 50.8 bits (120), Expect = 5e-07 Identities = 41/109 (37%), Positives = 45/109 (41%), Gaps = 15/109 (13%) Query: 35 PEPARAPPEPAP---PAEATGAP--APSRPCAPEPAASPAGPEEPGEPAGLGELGE---- 85 P PA A P+ P PA G P APSR AP P A PE GE AG E Sbjct: 344 PAPAEALPQQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQR 403 Query: 86 ----PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEG 130 P GP E PG P +P A + EA +D G GP G Sbjct: 404 HWVAPGGPYSAETPGVP--SPIAALKNVAEALGHSPKDPGGGGGPVRAG 450 >gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens] Length = 2462 Score = 50.4 bits (119), Expect = 7e-07 Identities = 41/108 (37%), Positives = 51/108 (47%), Gaps = 15/108 (13%) Query: 35 PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG 94 PE AP EP P +EATGAP P P P P+A P P P E E E P Sbjct: 770 PEDIPAPTEPTPASEATGAPTPP-PAPPSPSAPP--PVVPKE-----EKEEETAAAPPVE 821 Query: 95 PGDPAAAPAEAEEQAVEARQEEEQ-----DLDGEKGPSSEGPEEEDGE 137 G+ PA AEE AV+ + EE + E+GP ++G + E E Sbjct: 822 EGEEQKPPA-AEELAVDTGKAEEPVKSECTEEAEEGP-AKGKDAEAAE 867 Score = 36.6 bits (83), Expect = 0.011 Identities = 44/175 (25%), Positives = 58/175 (33%), Gaps = 41/175 (23%) Query: 28 RRGAAASPEPARAPP-----------------EPAPPAEATGAPAPSRPCAPEP---AAS 67 ++ AA+ E A PP E AEAT + P P AA Sbjct: 684 KKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAK 743 Query: 68 PAGPEEPGEPAGLGELGEPAGPGEPE------------------GPGDPAAAPAEAEEQA 109 G P PA LG G P GP P P P A P+ + Sbjct: 744 DTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPP 803 Query: 110 VEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEE 164 V ++E+E++ P EG E++ GK + K EE EE Sbjct: 804 VVPKEEKEEE-TAAAPPVEEGEEQKPPAAEELAVDTGK--AEEPVKSECTEEAEE 855 Score = 31.6 bits (70), Expect = 0.34 Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 9/75 (12%) Query: 42 PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGP--GDPA 99 P P PP E A P AP+P+A P PG P LG L + A P P P +P Sbjct: 1045 PFPVPPREVIKAS----PHAPDPSAFSYAP--PGHPLPLG-LHDTARPVLPRPPTISNPP 1097 Query: 100 AAPAEAEEQAVEARQ 114 + A+ +V RQ Sbjct: 1098 PLISSAKHPSVLERQ 1112 Score = 30.4 bits (67), Expect = 0.77 Identities = 26/84 (30%), Positives = 33/84 (39%), Gaps = 2/84 (2%) Query: 26 LVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPA-GPEEPG-EPAGLGEL 83 L +R AA P EP A PAP P P+ + P++PG P G Sbjct: 949 LKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRS 1008 Query: 84 GEPAGPGEPEGPGDPAAAPAEAEE 107 P E E P A AEA++ Sbjct: 1009 PAPPADKEAEKPVFFPAFAAEAQK 1032 Score = 26.9 bits (58), Expect = 8.5 Identities = 16/41 (39%), Positives = 17/41 (41%), Gaps = 1/41 (2%) Query: 47 PAEATGAPAPSRPCAPE-PAASPAGPEEPGEPAGLGELGEP 86 P+ A P P P A A P PG PAG G L P Sbjct: 2399 PSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGP 2439 >gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens] Length = 2524 Score = 50.4 bits (119), Expect = 7e-07 Identities = 41/108 (37%), Positives = 51/108 (47%), Gaps = 15/108 (13%) Query: 35 PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG 94 PE AP EP P +EATGAP P P P P+A P P P E E E P Sbjct: 787 PEDIPAPTEPTPASEATGAPTPP-PAPPSPSAPP--PVVPKE-----EKEEETAAAPPVE 838 Query: 95 PGDPAAAPAEAEEQAVEARQEEEQ-----DLDGEKGPSSEGPEEEDGE 137 G+ PA AEE AV+ + EE + E+GP ++G + E E Sbjct: 839 EGEEQKPPA-AEELAVDTGKAEEPVKSECTEEAEEGP-AKGKDAEAAE 884 Score = 37.0 bits (84), Expect = 0.008 Identities = 37/145 (25%), Positives = 48/145 (33%), Gaps = 10/145 (6%) Query: 27 VRRGAAASPEPARAPPE----PAPPAEA---TGAPAPSRPCAPEPAASPAGPEEPGEPAG 79 V RG + P + P+P EA TG P P P GP P P Sbjct: 731 VPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTP-PPED 789 Query: 80 LGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGF 139 + EP E G P AP +EE+++ P EG E++ Sbjct: 790 IPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAE 849 Query: 140 SFKYSPGKLRGNQYKKMMTKEELEE 164 GK + K EE EE Sbjct: 850 ELAVDTGK--AEEPVKSECTEEAEE 872 Score = 34.3 bits (77), Expect = 0.053 Identities = 33/92 (35%), Positives = 40/92 (43%), Gaps = 19/92 (20%) Query: 26 LVRRGAAASP------EPAR---APPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPG- 75 L +R AA P EP R AP +PAPPA P P + PE A P++PG Sbjct: 966 LKQRAAAIPPIVTKVHEPPREDAAPTKPAPPA-----PPPPQNLQPESDA----PQQPGS 1016 Query: 76 EPAGLGELGEPAGPGEPEGPGDPAAAPAEAEE 107 P G P E E P A AEA++ Sbjct: 1017 SPRGKSRSPAPPADKEAEKPVFFPAFAAEAQK 1048 Score = 31.6 bits (70), Expect = 0.34 Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 9/75 (12%) Query: 42 PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGP--GDPA 99 P P PP E A P AP+P+A P PG P LG L + A P P P +P Sbjct: 1061 PFPVPPREVIKAS----PHAPDPSAFSYAP--PGHPLPLG-LHDTARPVLPRPPTISNPP 1113 Query: 100 AAPAEAEEQAVEARQ 114 + A+ +V RQ Sbjct: 1114 PLISSAKHPSVLERQ 1128 Score = 26.9 bits (58), Expect = 8.5 Identities = 16/41 (39%), Positives = 17/41 (41%), Gaps = 1/41 (2%) Query: 47 PAEATGAPAPSRPCAPE-PAASPAGPEEPGEPAGLGELGEP 86 P+ A P P P A A P PG PAG G L P Sbjct: 2461 PSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGP 2501 >gi|153070260 myristoylated alanine-rich protein kinase C substrate [Homo sapiens] Length = 332 Score = 50.4 bits (119), Expect = 7e-07 Identities = 48/139 (34%), Positives = 59/139 (42%), Gaps = 19/139 (13%) Query: 31 AAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPG 90 AA EPA A A P+ A P+ APE ASP E P E G Sbjct: 66 AADKEEPAAAGSGAASPSAAEKGE-PAAAAAPEAGASPVEKEAPAE-------------G 111 Query: 91 EPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKLRG 150 E PG P AA EA A + +D PS+E P+++ + FSFK S KL G Sbjct: 112 EAAEPGSPTAAEGEAASAASSTSSPKAED-GATPSPSNETPKKKK-KRFSFKKS-FKLSG 168 Query: 151 NQYKKMMTKEELEEEQRTE 169 +KK K+E E E Sbjct: 169 FSFKK--NKKEAGEGGEAE 185 Score = 39.3 bits (90), Expect = 0.002 Identities = 37/112 (33%), Positives = 44/112 (39%), Gaps = 12/112 (10%) Query: 31 AAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGP--------EEPGEPAGLGE 82 AA A P+ A P EA A AP +P A + + P EE G A E Sbjct: 223 AAGEEGAAGGDPQEAKPQEA--AVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACE 280 Query: 83 LGEPAGPG-EPEGPGDPAAAP-AEAEEQAVEARQEEEQDLDGEKGPSSEGPE 132 AGPG PE PA P A A A A +E Q + P +E E Sbjct: 281 APSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332 Score = 37.4 bits (85), Expect = 0.006 Identities = 33/105 (31%), Positives = 40/105 (38%), Gaps = 6/105 (5%) Query: 38 ARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD 97 A AP EA G A + A AAS PGE A GE G G + P + Sbjct: 184 AEAPAAEGGKDEAAGGAAAA--AAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQE 241 Query: 98 PAAA----PAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEG 138 A A PA E +A E + E+ E G S+ E G Sbjct: 242 AAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAG 286 Score = 30.4 bits (67), Expect = 0.77 Identities = 20/47 (42%), Positives = 23/47 (48%), Gaps = 3/47 (6%) Query: 30 GAAASPEPARAP-PEPAPPAEATGAPAPSRPCAPE--PAASPAGPEE 73 G A PE AP EPA A ++ APS+ PE P A PA E Sbjct: 286 GPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332 Score = 28.5 bits (62), Expect = 2.9 Identities = 24/78 (30%), Positives = 29/78 (37%), Gaps = 18/78 (23%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89 GA+A+ A + P P E APA EEP A P+ Sbjct: 273 GASAAACEAPSAAGPGAPPEQEAAPA----------------EEPAAAAASSACAAPSQE 316 Query: 90 GEPEGPGDPAAAPAEAEE 107 +PE P A PAEA E Sbjct: 317 AQPE--CSPEAPPAEAAE 332 >gi|32307177 forkhead box G1 [Homo sapiens] Length = 489 Score = 50.4 bits (119), Expect = 7e-07 Identities = 44/141 (31%), Positives = 58/141 (41%), Gaps = 19/141 (13%) Query: 35 PEPARAPPEPAPPA----EATGAPAPSRPCAPEPAASPAGPEEPGEPA-------GLGEL 83 P + PP P PPA + GAPA P+ P P P A GLG Sbjct: 68 PPQQQQPPPPPPPAPQPPQTRGAPAADDDKGPQQLLLPPPPPPPPAAALDGAKADGLGGK 127 Query: 84 GEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKY 143 GEP G GPG+ A + +E+ A EE++ GE G EG +E GE + KY Sbjct: 128 GEPGG-----GPGELAPVGPDEKEKGAGAGGEEKKGA-GEGGKDGEGGKE--GEKKNGKY 179 Query: 144 SPGKLRGNQYKKMMTKEELEE 164 N M ++ E+ Sbjct: 180 EKPPFSYNALIMMAIRQSPEK 200 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 49.7 bits (117), Expect = 1e-06 Identities = 39/116 (33%), Positives = 44/116 (37%), Gaps = 8/116 (6%) Query: 29 RGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPE----EPGEPAGLGE 82 RG P P P P E TG P P P PAGP G P G+G Sbjct: 1060 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1119 Query: 83 LGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEE-EQDLDGEKG-PSSEGPEEEDG 136 LG P GEP G P + R E+ E GE G P +GP +DG Sbjct: 1120 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDG 1175 Score = 40.0 bits (92), Expect = 0.001 Identities = 32/110 (29%), Positives = 38/110 (34%), Gaps = 16/110 (14%) Query: 41 PPEPAPPAEATGAPAPSRPCA-------------PEPAASPAGPEEPGEPAGLGELGEPA 87 PP P PA GA P P P + SP EPG GE GE Sbjct: 1095 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1154 Query: 88 GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDG 136 G+P PG P ++ G+ GP E GP +DG Sbjct: 1155 ESGQPGEPGPPGPKGPTGDDG--PKGNPGPVGFPGDPGPPGEGGPRGQDG 1202 Score = 38.5 bits (88), Expect = 0.003 Identities = 36/119 (30%), Positives = 40/119 (33%), Gaps = 20/119 (16%) Query: 30 GAAASP-----EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELG 84 G A P E PP PA GA P P P GP PG G G Sbjct: 908 GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP--PGAAGEKGVPG 965 Query: 85 E--PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137 E P GP +G P P A V DG+KG P +G + GE Sbjct: 966 EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE-------DGDKGEVGDPGQKGTKGNKGE 1017 Score = 37.7 bits (86), Expect = 0.005 Identities = 36/120 (30%), Positives = 40/120 (33%), Gaps = 29/120 (24%) Query: 28 RRGAAASPEPARAPPEPAP------PAE-----ATGAPAPSRPCAPEPAASPAGPEEPGE 76 + G P P AP + P P E G P P PAG PGE Sbjct: 876 KEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG--SPGE 933 Query: 77 PAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG 136 G G PG P G P AA E+ + GEKGP GP DG Sbjct: 934 RGAAGSGGPIGPPGRPGPQGPPGAA--------------GEKGVPGEKGPI--GPTGRDG 977 Score = 37.7 bits (86), Expect = 0.005 Identities = 34/122 (27%), Positives = 41/122 (33%), Gaps = 12/122 (9%) Query: 29 RGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86 RG + P EP PP TG P P P P P PGE G+ G Sbjct: 1147 RGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN--PGPVGFPGDPGPPGEGGPRGQDGAK 1204 Query: 87 AGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPG 146 GE PG P +P E G++GP+ E G K PG Sbjct: 1205 GDRGEDGEPGQP-GSPGPTGENGPPGPL-------GKRGPAGSPGSEGRQGGKGAKGDPG 1256 Query: 147 KL 148 + Sbjct: 1257 AI 1258 Score = 37.0 bits (84), Expect = 0.008 Identities = 44/151 (29%), Positives = 50/151 (33%), Gaps = 43/151 (28%) Query: 29 RGAAASPEPARAPPEPAPP-----AEATGAPAPSRPCAP---EPAASPAGPEEPGEPAGL 80 RGAA S P P P P A G P P P + P G P P G+ Sbjct: 934 RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV 993 Query: 81 ----------------------GELGEPAGPGEPEGP-GDPAAAPAEAEEQAVEAR---- 113 GE G P PG P GP G P AA A+ E A + Sbjct: 994 AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG-PIGPVGQPGAAGADGEPGARGPQGHFG 1052 Query: 114 ---QEEEQDLDGEKGP----SSEGPEEEDGE 137 E + +G GP GP E GE Sbjct: 1053 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1083 Score = 36.2 bits (82), Expect = 0.014 Identities = 40/142 (28%), Positives = 52/142 (36%), Gaps = 21/142 (14%) Query: 26 LVRRGAAASP--EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE----------E 73 L +RG A SP E + A GAP + P P A GP+ + Sbjct: 1231 LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1290 Query: 74 PGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVE----ARQEEEQDLDGEKG-PSS 128 G P G+ G P G P PG A A+ E+ EQ G++G P Sbjct: 1291 QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1350 Query: 129 EGPEEEDGE----GFSFKYSPG 146 +G + GE G S PG Sbjct: 1351 QGSPGQKGEMGIPGASGPIGPG 1372 Score = 35.4 bits (80), Expect = 0.024 Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 29/102 (28%) Query: 30 GAAASPEPARAPPEPAPPAEA-----TGAPA-------PSRPCAPEPAA----------- 66 G +P P P +P PP E GA P +P +P P Sbjct: 1175 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1234 Query: 67 SPAG-PEEPGEPAGLGELGEP---AGPGE--PEGPGDPAAAP 102 PAG P G G G G+P PG+ P GP PA P Sbjct: 1235 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP 1276 Score = 35.0 bits (79), Expect = 0.031 Identities = 29/103 (28%), Positives = 35/103 (33%), Gaps = 22/103 (21%) Query: 43 EPAPPAE-----ATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE------ 91 EP PP + G P P P P G +PG P G G P PG+ Sbjct: 558 EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG--KPGLPGMPGSDGPPGHPGKEGPPGT 615 Query: 92 -----PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE 129 P GP P P + V+ + L G KG E Sbjct: 616 KGNQGPSGPQGPLGYPGPRGVKGVDG----IRGLKGHKGEKGE 654 Score = 35.0 bits (79), Expect = 0.031 Identities = 25/81 (30%), Positives = 28/81 (34%), Gaps = 13/81 (16%) Query: 29 RGAAASPEPARAPPEPAPPAEA-----TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGEL 83 +G P P P E TG P P P+ AA GP +GE Sbjct: 805 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP--------MGER 856 Query: 84 GEPAGPGEPEGPGDPAAAPAE 104 G P PG P G P A E Sbjct: 857 GHPGPPGPPGEQGLPGTAGKE 877 Score = 35.0 bits (79), Expect = 0.031 Identities = 36/109 (33%), Positives = 42/109 (38%), Gaps = 14/109 (12%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGL-GELGEPAG 88 G + SP P P E +P P P P GP P G G +G P Sbjct: 1130 GESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG-PKGPTGDDGPKGNPGPVGFPGD 1188 Query: 89 PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDG 136 PG P G G P ++ A R E DGE G P S GP E+G Sbjct: 1189 PG-PPGEGGP-----RGQDGAKGDRGE-----DGEPGQPGSPGPTGENG 1226 Score = 34.3 bits (77), Expect = 0.053 Identities = 37/121 (30%), Positives = 42/121 (34%), Gaps = 12/121 (9%) Query: 35 PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG 94 P R P P P G P P P P P P PG+ +G G+ PG P Sbjct: 786 PPGERGLPGPQGP---NGFPGPKGP--PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 840 Query: 95 PGDPAAA----PAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG-EGFSFKYSPGKLR 149 G AA P EQ L G G EG + + G G K P LR Sbjct: 841 VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG--KEGTKGDPGPPGAPGKDGPAGLR 898 Query: 150 G 150 G Sbjct: 899 G 899 Score = 33.5 bits (75), Expect = 0.091 Identities = 33/117 (28%), Positives = 39/117 (33%), Gaps = 29/117 (24%) Query: 29 RGAAASPEPA---RAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE 85 +G A EP PP P PA G P +P +PGE G G Sbjct: 299 KGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQ--------GNPGPVGDPGERGPPGRAGL 350 Query: 86 PAGPGEPEGPG----------------DPAAAPAEAEEQAVEARQEEEQDLDGEKGP 126 P G P PG P A EA+ QA+ Q+ L G GP Sbjct: 351 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAI--LQQARLALRGPPGP 405 Score = 32.3 bits (72), Expect = 0.20 Identities = 32/97 (32%), Positives = 39/97 (40%), Gaps = 19/97 (19%) Query: 52 GAPAPSRPCAPEPAASPAGPE-EPGEPAGLGE---LGEPAGPGEP--EGP----GDPAAA 101 G P PE GP +PG P +GE LG P PG P +GP G P Sbjct: 674 GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 733 Query: 102 PAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGE 137 A E+ A + L G+ GP E GP G+ Sbjct: 734 GASGEKGA--------RGLSGKSGPRGERGPTGPRGQ 762 Score = 32.3 bits (72), Expect = 0.20 Identities = 29/102 (28%), Positives = 34/102 (33%), Gaps = 10/102 (9%) Query: 41 PPEPAPPAEATGAPAP----SRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPG 96 PP P A G P P P P P G+ G+ G P PG+ +GP Sbjct: 837 PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK-DGPA 895 Query: 97 DPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDGE 137 P E L G +GPS GP GE Sbjct: 896 GLRGFPGERGLPGTAG----GPGLKGNEGPSGPPGPAGSPGE 933 Score = 31.2 bits (69), Expect = 0.45 Identities = 33/121 (27%), Positives = 44/121 (36%), Gaps = 21/121 (17%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPC---APEPAASPAGPE------EPGEPAG 79 +G P P +P + G P S P P PAGP+ PG P Sbjct: 1342 KGDRGLPGPQGSPGQKGE----MGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK- 1396 Query: 80 LGELGEPAGPGEPEGPGD-----PAAAPAEAEEQAVEAR-QEEEQDLDGEKGPSSEGPEE 133 GE G PG P PG+ P P + +R +E++ + P S G E Sbjct: 1397 -GEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLE 1455 Query: 134 E 134 E Sbjct: 1456 E 1456 Score = 30.8 bits (68), Expect = 0.59 Identities = 33/132 (25%), Positives = 42/132 (31%), Gaps = 12/132 (9%) Query: 30 GAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87 GA P P E E G P S P P GP P G+ + P Sbjct: 491 GAQGLPGPPGEDGERGDDGEIGPRGLPGES---GPRGLLGPKGPPGIPGPPGVRGMDGPQ 547 Query: 88 GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL--DGEKGPSSEG-----PEEEDGEGFS 140 GP GP P + + + + GEKGP + P + G Sbjct: 548 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 607 Query: 141 FKYSPGKLRGNQ 152 K P +GNQ Sbjct: 608 GKEGPPGTKGNQ 619 Score = 29.3 bits (64), Expect = 1.7 Identities = 30/97 (30%), Positives = 33/97 (34%), Gaps = 25/97 (25%) Query: 62 PEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG-PGDPAAAPAEAEEQAVEARQ------ 114 P P P P GE LG P GP P+G G P A A AR Sbjct: 412 PGPLGQPGSPGLKGESGDLG----PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG 467 Query: 115 -------EEEQDLDGEKGPSSE-------GPEEEDGE 137 + L GEKG + GP EDGE Sbjct: 468 VKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE 504 Score = 29.3 bits (64), Expect = 1.7 Identities = 27/105 (25%), Positives = 36/105 (34%), Gaps = 15/105 (14%) Query: 37 PARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEE-------PGEPAGLGELGEPA 87 P P P PP G P P+ P G + PG +G GE Sbjct: 528 PKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKG 587 Query: 88 GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGP 131 G+P PG P ++ +E G +GPS +GP Sbjct: 588 PQGKPGLPGMPG-----SDGPPGHPGKEGPPGTKGNQGPSGPQGP 627 Score = 28.5 bits (62), Expect = 2.9 Identities = 25/95 (26%), Positives = 31/95 (32%), Gaps = 5/95 (5%) Query: 47 PAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAE 106 P G P A +G + P P G L P GP GP P P + + Sbjct: 756 PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK-D 814 Query: 107 EQAVEARQEEEQDLDGEKGPSSE----GPEEEDGE 137 Q E G+ GP GP+ GE Sbjct: 815 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGE 849 Score = 28.1 bits (61), Expect = 3.8 Identities = 24/83 (28%), Positives = 32/83 (38%), Gaps = 14/83 (16%) Query: 68 PAGPEEPGEPAGLGELGEPAGPGEPEGPGD-----PAAAPAEAEEQAVEARQEEE----- 117 P P E G G G P PGE GD P P E+ + + + Sbjct: 478 PGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGP 537 Query: 118 ---QDLDGEKGP-SSEGPEEEDG 136 + +DG +GP S GP+ E G Sbjct: 538 PGVRGMDGPQGPKGSLGPQGEPG 560 Score = 27.3 bits (59), Expect = 6.5 Identities = 27/102 (26%), Positives = 33/102 (32%), Gaps = 28/102 (27%) Query: 23 AWLLVRRGAAASPEPARAPPEPAPPAEA-----TGAPAP--SRPCAPEPAASPAGPEEP- 74 A L+ G +P P P E PP A GAP P + P S G + P Sbjct: 321 AGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPV 380 Query: 75 --------------------GEPAGLGELGEPAGPGEPEGPG 96 G P +G G P G+P PG Sbjct: 381 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG 422 Score = 26.9 bits (58), Expect = 8.5 Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 1/61 (1%) Query: 43 EPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGEPAGPGEPEGPGDPAAA 101 +P P E + P E A P G + E GEPA L GP PEGP Sbjct: 267 DPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGP 326 Query: 102 P 102 P Sbjct: 327 P 327 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 49.7 bits (117), Expect = 1e-06 Identities = 39/116 (33%), Positives = 44/116 (37%), Gaps = 8/116 (6%) Query: 29 RGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPE----EPGEPAGLGE 82 RG P P P P E TG P P P PAGP G P G+G Sbjct: 1039 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1098 Query: 83 LGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEE-EQDLDGEKG-PSSEGPEEEDG 136 LG P GEP G P + R E+ E GE G P +GP +DG Sbjct: 1099 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDG 1154 Score = 40.0 bits (92), Expect = 0.001 Identities = 32/110 (29%), Positives = 38/110 (34%), Gaps = 16/110 (14%) Query: 41 PPEPAPPAEATGAPAPSRPCA-------------PEPAASPAGPEEPGEPAGLGELGEPA 87 PP P PA GA P P P + SP EPG GE GE Sbjct: 1074 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1133 Query: 88 GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDG 136 G+P PG P ++ G+ GP E GP +DG Sbjct: 1134 ESGQPGEPGPPGPKGPTGDDG--PKGNPGPVGFPGDPGPPGEGGPRGQDG 1181 Score = 38.5 bits (88), Expect = 0.003 Identities = 36/119 (30%), Positives = 40/119 (33%), Gaps = 20/119 (16%) Query: 30 GAAASP-----EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELG 84 G A P E PP PA GA P P P GP PG G G Sbjct: 887 GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP--PGAAGEKGVPG 944 Query: 85 E--PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137 E P GP +G P P A V DG+KG P +G + GE Sbjct: 945 EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE-------DGDKGEVGDPGQKGTKGNKGE 996 Score = 37.7 bits (86), Expect = 0.005 Identities = 36/120 (30%), Positives = 40/120 (33%), Gaps = 29/120 (24%) Query: 28 RRGAAASPEPARAPPEPAP------PAE-----ATGAPAPSRPCAPEPAASPAGPEEPGE 76 + G P P AP + P P E G P P PAG PGE Sbjct: 855 KEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG--SPGE 912 Query: 77 PAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG 136 G G PG P G P AA E+ + GEKGP GP DG Sbjct: 913 RGAAGSGGPIGPPGRPGPQGPPGAA--------------GEKGVPGEKGPI--GPTGRDG 956 Score = 37.7 bits (86), Expect = 0.005 Identities = 34/122 (27%), Positives = 41/122 (33%), Gaps = 12/122 (9%) Query: 29 RGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86 RG + P EP PP TG P P P P P PGE G+ G Sbjct: 1126 RGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN--PGPVGFPGDPGPPGEGGPRGQDGAK 1183 Query: 87 AGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPG 146 GE PG P +P E G++GP+ E G K PG Sbjct: 1184 GDRGEDGEPGQP-GSPGPTGENGPPGPL-------GKRGPAGSPGSEGRQGGKGAKGDPG 1235 Query: 147 KL 148 + Sbjct: 1236 AI 1237 Score = 37.0 bits (84), Expect = 0.008 Identities = 44/151 (29%), Positives = 50/151 (33%), Gaps = 43/151 (28%) Query: 29 RGAAASPEPARAPPEPAPP-----AEATGAPAPSRPCAP---EPAASPAGPEEPGEPAGL 80 RGAA S P P P P A G P P P + P G P P G+ Sbjct: 913 RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV 972 Query: 81 ----------------------GELGEPAGPGEPEGP-GDPAAAPAEAEEQAVEAR---- 113 GE G P PG P GP G P AA A+ E A + Sbjct: 973 AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG-PIGPVGQPGAAGADGEPGARGPQGHFG 1031 Query: 114 ---QEEEQDLDGEKGP----SSEGPEEEDGE 137 E + +G GP GP E GE Sbjct: 1032 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1062 Score = 36.2 bits (82), Expect = 0.014 Identities = 40/142 (28%), Positives = 52/142 (36%), Gaps = 21/142 (14%) Query: 26 LVRRGAAASP--EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE----------E 73 L +RG A SP E + A GAP + P P A GP+ + Sbjct: 1210 LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1269 Query: 74 PGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVE----ARQEEEQDLDGEKG-PSS 128 G P G+ G P G P PG A A+ E+ EQ G++G P Sbjct: 1270 QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1329 Query: 129 EGPEEEDGE----GFSFKYSPG 146 +G + GE G S PG Sbjct: 1330 QGSPGQKGEMGIPGASGPIGPG 1351 Score = 35.4 bits (80), Expect = 0.024 Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 29/102 (28%) Query: 30 GAAASPEPARAPPEPAPPAEA-----TGAPA-------PSRPCAPEPAA----------- 66 G +P P P +P PP E GA P +P +P P Sbjct: 1154 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1213 Query: 67 SPAG-PEEPGEPAGLGELGEP---AGPGE--PEGPGDPAAAP 102 PAG P G G G G+P PG+ P GP PA P Sbjct: 1214 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP 1255 Score = 35.0 bits (79), Expect = 0.031 Identities = 29/103 (28%), Positives = 35/103 (33%), Gaps = 22/103 (21%) Query: 43 EPAPPAE-----ATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE------ 91 EP PP + G P P P P G +PG P G G P PG+ Sbjct: 537 EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG--KPGLPGMPGSDGPPGHPGKEGPPGT 594 Query: 92 -----PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE 129 P GP P P + V+ + L G KG E Sbjct: 595 KGNQGPSGPQGPLGYPGPRGVKGVDG----IRGLKGHKGEKGE 633 Score = 35.0 bits (79), Expect = 0.031 Identities = 25/81 (30%), Positives = 28/81 (34%), Gaps = 13/81 (16%) Query: 29 RGAAASPEPARAPPEPAPPAEA-----TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGEL 83 +G P P P E TG P P P+ AA GP +GE Sbjct: 784 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP--------MGER 835 Query: 84 GEPAGPGEPEGPGDPAAAPAE 104 G P PG P G P A E Sbjct: 836 GHPGPPGPPGEQGLPGTAGKE 856 Score = 35.0 bits (79), Expect = 0.031 Identities = 36/109 (33%), Positives = 42/109 (38%), Gaps = 14/109 (12%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGL-GELGEPAG 88 G + SP P P E +P P P P GP P G G +G P Sbjct: 1109 GESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG-PKGPTGDDGPKGNPGPVGFPGD 1167 Query: 89 PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDG 136 PG P G G P ++ A R E DGE G P S GP E+G Sbjct: 1168 PG-PPGEGGP-----RGQDGAKGDRGE-----DGEPGQPGSPGPTGENG 1205 Score = 34.3 bits (77), Expect = 0.053 Identities = 37/121 (30%), Positives = 42/121 (34%), Gaps = 12/121 (9%) Query: 35 PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG 94 P R P P P G P P P P P P PG+ +G G+ PG P Sbjct: 765 PPGERGLPGPQGP---NGFPGPKGP--PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 819 Query: 95 PGDPAAA----PAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG-EGFSFKYSPGKLR 149 G AA P EQ L G G EG + + G G K P LR Sbjct: 820 VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG--KEGTKGDPGPPGAPGKDGPAGLR 877 Query: 150 G 150 G Sbjct: 878 G 878 Score = 33.9 bits (76), Expect = 0.069 Identities = 23/76 (30%), Positives = 27/76 (35%), Gaps = 7/76 (9%) Query: 28 RRGAAASPEPARAPPEPAPPAEATGAP-----APSRPCAPEPAASPAGPEEPGEPAGLGE 82 +R P P P ++A P P EP GP P PAGL Sbjct: 245 QRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGL-- 302 Query: 83 LGEPAGPGEPEGPGDP 98 +G P G P GDP Sbjct: 303 IGPPGIQGNPGPVGDP 318 Score = 33.5 bits (75), Expect = 0.091 Identities = 33/117 (28%), Positives = 39/117 (33%), Gaps = 29/117 (24%) Query: 29 RGAAASPEPA---RAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE 85 +G A EP PP P PA G P +P +PGE G G Sbjct: 278 KGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQ--------GNPGPVGDPGERGPPGRAGL 329 Query: 86 PAGPGEPEGPG----------------DPAAAPAEAEEQAVEARQEEEQDLDGEKGP 126 P G P PG P A EA+ QA+ Q+ L G GP Sbjct: 330 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAI--LQQARLALRGPPGP 384 Score = 32.3 bits (72), Expect = 0.20 Identities = 32/97 (32%), Positives = 39/97 (40%), Gaps = 19/97 (19%) Query: 52 GAPAPSRPCAPEPAASPAGPE-EPGEPAGLGE---LGEPAGPGEP--EGP----GDPAAA 101 G P PE GP +PG P +GE LG P PG P +GP G P Sbjct: 653 GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 712 Query: 102 PAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGE 137 A E+ A + L G+ GP E GP G+ Sbjct: 713 GASGEKGA--------RGLSGKSGPRGERGPTGPRGQ 741 Score = 32.3 bits (72), Expect = 0.20 Identities = 29/102 (28%), Positives = 34/102 (33%), Gaps = 10/102 (9%) Query: 41 PPEPAPPAEATGAPAP----SRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPG 96 PP P A G P P P P P G+ G+ G P PG+ +GP Sbjct: 816 PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK-DGPA 874 Query: 97 DPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDGE 137 P E L G +GPS GP GE Sbjct: 875 GLRGFPGERGLPGTAG----GPGLKGNEGPSGPPGPAGSPGE 912 Score = 31.2 bits (69), Expect = 0.45 Identities = 33/121 (27%), Positives = 44/121 (36%), Gaps = 21/121 (17%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPC---APEPAASPAGPE------EPGEPAG 79 +G P P +P + G P S P P PAGP+ PG P Sbjct: 1321 KGDRGLPGPQGSPGQKGE----MGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK- 1375 Query: 80 LGELGEPAGPGEPEGPGD-----PAAAPAEAEEQAVEAR-QEEEQDLDGEKGPSSEGPEE 133 GE G PG P PG+ P P + +R +E++ + P S G E Sbjct: 1376 -GEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLE 1434 Query: 134 E 134 E Sbjct: 1435 E 1435 Score = 30.8 bits (68), Expect = 0.59 Identities = 33/132 (25%), Positives = 42/132 (31%), Gaps = 12/132 (9%) Query: 30 GAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87 GA P P E E G P S P P GP P G+ + P Sbjct: 470 GAQGLPGPPGEDGERGDDGEIGPRGLPGES---GPRGLLGPKGPPGIPGPPGVRGMDGPQ 526 Query: 88 GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL--DGEKGPSSEG-----PEEEDGEGFS 140 GP GP P + + + + GEKGP + P + G Sbjct: 527 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 586 Query: 141 FKYSPGKLRGNQ 152 K P +GNQ Sbjct: 587 GKEGPPGTKGNQ 598 Score = 29.3 bits (64), Expect = 1.7 Identities = 30/97 (30%), Positives = 33/97 (34%), Gaps = 25/97 (25%) Query: 62 PEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG-PGDPAAAPAEAEEQAVEARQ------ 114 P P P P GE LG P GP P+G G P A A AR Sbjct: 391 PGPLGQPGSPGLKGESGDLG----PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG 446 Query: 115 -------EEEQDLDGEKGPSSE-------GPEEEDGE 137 + L GEKG + GP EDGE Sbjct: 447 VKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE 483 Score = 29.3 bits (64), Expect = 1.7 Identities = 27/105 (25%), Positives = 36/105 (34%), Gaps = 15/105 (14%) Query: 37 PARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEE-------PGEPAGLGELGEPA 87 P P P PP G P P+ P G + PG +G GE Sbjct: 507 PKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKG 566 Query: 88 GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGP 131 G+P PG P ++ +E G +GPS +GP Sbjct: 567 PQGKPGLPGMPG-----SDGPPGHPGKEGPPGTKGNQGPSGPQGP 606 Score = 28.5 bits (62), Expect = 2.9 Identities = 25/95 (26%), Positives = 31/95 (32%), Gaps = 5/95 (5%) Query: 47 PAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAE 106 P G P A +G + P P G L P GP GP P P + + Sbjct: 735 PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK-D 793 Query: 107 EQAVEARQEEEQDLDGEKGPSSE----GPEEEDGE 137 Q E G+ GP GP+ GE Sbjct: 794 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGE 828 Score = 28.1 bits (61), Expect = 3.8 Identities = 24/83 (28%), Positives = 32/83 (38%), Gaps = 14/83 (16%) Query: 68 PAGPEEPGEPAGLGELGEPAGPGEPEGPGD-----PAAAPAEAEEQAVEARQEEE----- 117 P P E G G G P PGE GD P P E+ + + + Sbjct: 457 PGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGP 516 Query: 118 ---QDLDGEKGP-SSEGPEEEDG 136 + +DG +GP S GP+ E G Sbjct: 517 PGVRGMDGPQGPKGSLGPQGEPG 539 Score = 27.3 bits (59), Expect = 6.5 Identities = 27/102 (26%), Positives = 33/102 (32%), Gaps = 28/102 (27%) Query: 23 AWLLVRRGAAASPEPARAPPEPAPPAEA-----TGAPAP--SRPCAPEPAASPAGPEEP- 74 A L+ G +P P P E PP A GAP P + P S G + P Sbjct: 300 AGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPV 359 Query: 75 --------------------GEPAGLGELGEPAGPGEPEGPG 96 G P +G G P G+P PG Sbjct: 360 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG 401 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 49.7 bits (117), Expect = 1e-06 Identities = 39/116 (33%), Positives = 44/116 (37%), Gaps = 8/116 (6%) Query: 29 RGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPE----EPGEPAGLGE 82 RG P P P P E TG P P P PAGP G P G+G Sbjct: 1146 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1205 Query: 83 LGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEE-EQDLDGEKG-PSSEGPEEEDG 136 LG P GEP G P + R E+ E GE G P +GP +DG Sbjct: 1206 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDG 1261 Score = 40.0 bits (92), Expect = 0.001 Identities = 32/110 (29%), Positives = 38/110 (34%), Gaps = 16/110 (14%) Query: 41 PPEPAPPAEATGAPAPSRPCA-------------PEPAASPAGPEEPGEPAGLGELGEPA 87 PP P PA GA P P P + SP EPG GE GE Sbjct: 1181 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1240 Query: 88 GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDG 136 G+P PG P ++ G+ GP E GP +DG Sbjct: 1241 ESGQPGEPGPPGPKGPTGDDG--PKGNPGPVGFPGDPGPPGEGGPRGQDG 1288 Score = 38.5 bits (88), Expect = 0.003 Identities = 36/119 (30%), Positives = 40/119 (33%), Gaps = 20/119 (16%) Query: 30 GAAASP-----EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELG 84 G A P E PP PA GA P P P GP PG G G Sbjct: 994 GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP--PGAAGEKGVPG 1051 Query: 85 E--PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137 E P GP +G P P A V DG+KG P +G + GE Sbjct: 1052 EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE-------DGDKGEVGDPGQKGTKGNKGE 1103 Score = 37.7 bits (86), Expect = 0.005 Identities = 36/120 (30%), Positives = 40/120 (33%), Gaps = 29/120 (24%) Query: 28 RRGAAASPEPARAPPEPAP------PAE-----ATGAPAPSRPCAPEPAASPAGPEEPGE 76 + G P P AP + P P E G P P PAG PGE Sbjct: 962 KEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG--SPGE 1019 Query: 77 PAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG 136 G G PG P G P AA E+ + GEKGP GP DG Sbjct: 1020 RGAAGSGGPIGPPGRPGPQGPPGAA--------------GEKGVPGEKGPI--GPTGRDG 1063 Score = 37.7 bits (86), Expect = 0.005 Identities = 34/122 (27%), Positives = 41/122 (33%), Gaps = 12/122 (9%) Query: 29 RGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86 RG + P EP PP TG P P P P P PGE G+ G Sbjct: 1233 RGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN--PGPVGFPGDPGPPGEGGPRGQDGAK 1290 Query: 87 AGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPG 146 GE PG P +P E G++GP+ E G K PG Sbjct: 1291 GDRGEDGEPGQP-GSPGPTGENGPPGPL-------GKRGPAGSPGSEGRQGGKGAKGDPG 1342 Query: 147 KL 148 + Sbjct: 1343 AI 1344 Score = 37.0 bits (84), Expect = 0.008 Identities = 44/151 (29%), Positives = 50/151 (33%), Gaps = 43/151 (28%) Query: 29 RGAAASPEPARAPPEPAPP-----AEATGAPAPSRPCAP---EPAASPAGPEEPGEPAGL 80 RGAA S P P P P A G P P P + P G P P G+ Sbjct: 1020 RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV 1079 Query: 81 ----------------------GELGEPAGPGEPEGP-GDPAAAPAEAEEQAVEAR---- 113 GE G P PG P GP G P AA A+ E A + Sbjct: 1080 AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG-PIGPVGQPGAAGADGEPGARGPQGHFG 1138 Query: 114 ---QEEEQDLDGEKGP----SSEGPEEEDGE 137 E + +G GP GP E GE Sbjct: 1139 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1169 Score = 36.2 bits (82), Expect = 0.014 Identities = 40/142 (28%), Positives = 52/142 (36%), Gaps = 21/142 (14%) Query: 26 LVRRGAAASP--EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE----------E 73 L +RG A SP E + A GAP + P P A GP+ + Sbjct: 1317 LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1376 Query: 74 PGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVE----ARQEEEQDLDGEKG-PSS 128 G P G+ G P G P PG A A+ E+ EQ G++G P Sbjct: 1377 QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1436 Query: 129 EGPEEEDGE----GFSFKYSPG 146 +G + GE G S PG Sbjct: 1437 QGSPGQKGEMGIPGASGPIGPG 1458 Score = 35.4 bits (80), Expect = 0.024 Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 29/102 (28%) Query: 30 GAAASPEPARAPPEPAPPAEA-----TGAPA-------PSRPCAPEPAA----------- 66 G +P P P +P PP E GA P +P +P P Sbjct: 1261 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1320 Query: 67 SPAG-PEEPGEPAGLGELGEP---AGPGE--PEGPGDPAAAP 102 PAG P G G G G+P PG+ P GP PA P Sbjct: 1321 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP 1362 Score = 35.0 bits (79), Expect = 0.031 Identities = 29/103 (28%), Positives = 35/103 (33%), Gaps = 22/103 (21%) Query: 43 EPAPPAE-----ATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE------ 91 EP PP + G P P P P G +PG P G G P PG+ Sbjct: 644 EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG--KPGLPGMPGSDGPPGHPGKEGPPGT 701 Query: 92 -----PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE 129 P GP P P + V+ + L G KG E Sbjct: 702 KGNQGPSGPQGPLGYPGPRGVKGVDG----IRGLKGHKGEKGE 740 Score = 35.0 bits (79), Expect = 0.031 Identities = 25/81 (30%), Positives = 28/81 (34%), Gaps = 13/81 (16%) Query: 29 RGAAASPEPARAPPEPAPPAEA-----TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGEL 83 +G P P P E TG P P P+ AA GP +GE Sbjct: 891 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP--------MGER 942 Query: 84 GEPAGPGEPEGPGDPAAAPAE 104 G P PG P G P A E Sbjct: 943 GHPGPPGPPGEQGLPGTAGKE 963 Score = 35.0 bits (79), Expect = 0.031 Identities = 36/109 (33%), Positives = 42/109 (38%), Gaps = 14/109 (12%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGL-GELGEPAG 88 G + SP P P E +P P P P GP P G G +G P Sbjct: 1216 GESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG-PKGPTGDDGPKGNPGPVGFPGD 1274 Query: 89 PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDG 136 PG P G G P ++ A R E DGE G P S GP E+G Sbjct: 1275 PG-PPGEGGP-----RGQDGAKGDRGE-----DGEPGQPGSPGPTGENG 1312 Score = 34.3 bits (77), Expect = 0.053 Identities = 37/121 (30%), Positives = 42/121 (34%), Gaps = 12/121 (9%) Query: 35 PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG 94 P R P P P G P P P P P P PG+ +G G+ PG P Sbjct: 872 PPGERGLPGPQGP---NGFPGPKGP--PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 926 Query: 95 PGDPAAA----PAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG-EGFSFKYSPGKLR 149 G AA P EQ L G G EG + + G G K P LR Sbjct: 927 VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG--KEGTKGDPGPPGAPGKDGPAGLR 984 Query: 150 G 150 G Sbjct: 985 G 985 Score = 33.5 bits (75), Expect = 0.091 Identities = 33/117 (28%), Positives = 39/117 (33%), Gaps = 29/117 (24%) Query: 29 RGAAASPEPA---RAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE 85 +G A EP PP P PA G P +P +PGE G G Sbjct: 385 KGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQ--------GNPGPVGDPGERGPPGRAGL 436 Query: 86 PAGPGEPEGPG----------------DPAAAPAEAEEQAVEARQEEEQDLDGEKGP 126 P G P PG P A EA+ QA+ Q+ L G GP Sbjct: 437 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAI--LQQARLALRGPPGP 491 Score = 32.3 bits (72), Expect = 0.20 Identities = 32/97 (32%), Positives = 39/97 (40%), Gaps = 19/97 (19%) Query: 52 GAPAPSRPCAPEPAASPAGPE-EPGEPAGLGE---LGEPAGPGEP--EGP----GDPAAA 101 G P PE GP +PG P +GE LG P PG P +GP G P Sbjct: 760 GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 819 Query: 102 PAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGE 137 A E+ A + L G+ GP E GP G+ Sbjct: 820 GASGEKGA--------RGLSGKSGPRGERGPTGPRGQ 848 Score = 32.3 bits (72), Expect = 0.20 Identities = 29/102 (28%), Positives = 34/102 (33%), Gaps = 10/102 (9%) Query: 41 PPEPAPPAEATGAPAP----SRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPG 96 PP P A G P P P P P G+ G+ G P PG+ +GP Sbjct: 923 PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK-DGPA 981 Query: 97 DPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDGE 137 P E L G +GPS GP GE Sbjct: 982 GLRGFPGERGLPGTAG----GPGLKGNEGPSGPPGPAGSPGE 1019 Score = 31.2 bits (69), Expect = 0.45 Identities = 33/121 (27%), Positives = 44/121 (36%), Gaps = 21/121 (17%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPC---APEPAASPAGPE------EPGEPAG 79 +G P P +P + G P S P P PAGP+ PG P Sbjct: 1428 KGDRGLPGPQGSPGQKGE----MGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK- 1482 Query: 80 LGELGEPAGPGEPEGPGD-----PAAAPAEAEEQAVEAR-QEEEQDLDGEKGPSSEGPEE 133 GE G PG P PG+ P P + +R +E++ + P S G E Sbjct: 1483 -GEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLE 1541 Query: 134 E 134 E Sbjct: 1542 E 1542 Score = 30.8 bits (68), Expect = 0.59 Identities = 33/132 (25%), Positives = 42/132 (31%), Gaps = 12/132 (9%) Query: 30 GAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87 GA P P E E G P S P P GP P G+ + P Sbjct: 577 GAQGLPGPPGEDGERGDDGEIGPRGLPGES---GPRGLLGPKGPPGIPGPPGVRGMDGPQ 633 Query: 88 GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL--DGEKGPSSEG-----PEEEDGEGFS 140 GP GP P + + + + GEKGP + P + G Sbjct: 634 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 693 Query: 141 FKYSPGKLRGNQ 152 K P +GNQ Sbjct: 694 GKEGPPGTKGNQ 705 Score = 29.3 bits (64), Expect = 1.7 Identities = 30/97 (30%), Positives = 33/97 (34%), Gaps = 25/97 (25%) Query: 62 PEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG-PGDPAAAPAEAEEQAVEARQ------ 114 P P P P GE LG P GP P+G G P A A AR Sbjct: 498 PGPLGQPGSPGLKGESGDLG----PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG 553 Query: 115 -------EEEQDLDGEKGPSSE-------GPEEEDGE 137 + L GEKG + GP EDGE Sbjct: 554 VKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE 590 Score = 29.3 bits (64), Expect = 1.7 Identities = 27/105 (25%), Positives = 36/105 (34%), Gaps = 15/105 (14%) Query: 37 PARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEE-------PGEPAGLGELGEPA 87 P P P PP G P P+ P G + PG +G GE Sbjct: 614 PKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKG 673 Query: 88 GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGP 131 G+P PG P ++ +E G +GPS +GP Sbjct: 674 PQGKPGLPGMPG-----SDGPPGHPGKEGPPGTKGNQGPSGPQGP 713 Score = 28.5 bits (62), Expect = 2.9 Identities = 22/70 (31%), Positives = 25/70 (35%), Gaps = 1/70 (1%) Query: 32 AASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEE-PGEPAGLGELGEPAGPG 90 AA+ P E PA P PE A GP G P +G+ GE PG Sbjct: 373 AAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG 432 Query: 91 EPEGPGDPAA 100 PG A Sbjct: 433 RAGLPGSDGA 442 Score = 28.5 bits (62), Expect = 2.9 Identities = 25/95 (26%), Positives = 31/95 (32%), Gaps = 5/95 (5%) Query: 47 PAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAE 106 P G P A +G + P P G L P GP GP P P + + Sbjct: 842 PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK-D 900 Query: 107 EQAVEARQEEEQDLDGEKGPSSE----GPEEEDGE 137 Q E G+ GP GP+ GE Sbjct: 901 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGE 935 Score = 28.1 bits (61), Expect = 3.8 Identities = 24/83 (28%), Positives = 32/83 (38%), Gaps = 14/83 (16%) Query: 68 PAGPEEPGEPAGLGELGEPAGPGEPEGPGD-----PAAAPAEAEEQAVEARQEEE----- 117 P P E G G G P PGE GD P P E+ + + + Sbjct: 564 PGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGP 623 Query: 118 ---QDLDGEKGP-SSEGPEEEDG 136 + +DG +GP S GP+ E G Sbjct: 624 PGVRGMDGPQGPKGSLGPQGEPG 646 Score = 27.3 bits (59), Expect = 6.5 Identities = 27/102 (26%), Positives = 33/102 (32%), Gaps = 28/102 (27%) Query: 23 AWLLVRRGAAASPEPARAPPEPAPPAEA-----TGAPAP--SRPCAPEPAASPAGPEEP- 74 A L+ G +P P P E PP A GAP P + P S G + P Sbjct: 407 AGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPV 466 Query: 75 --------------------GEPAGLGELGEPAGPGEPEGPG 96 G P +G G P G+P PG Sbjct: 467 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG 508 >gi|194578898 hypothetical protein LOC100170841 [Homo sapiens] Length = 379 Score = 49.3 bits (116), Expect = 2e-06 Identities = 41/129 (31%), Positives = 54/129 (41%), Gaps = 32/129 (24%) Query: 38 ARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPG---EPEG 94 A APP PAP E PA S P EP++ P P PAGL EPAGPG P Sbjct: 154 ASAPPRPAPGLEPQRGPAASPP--QEPSSRP-----PSPPAGLST--EPAGPGTAPRPFL 204 Query: 95 PGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDGEGFSFKYSPGKLRGNQY 153 PG PA ++DG P++ E P +PG LR + Sbjct: 205 PGQPA-------------------EVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHF 245 Query: 154 KKMMTKEEL 162 +++ + +L Sbjct: 246 DRLIRRSKL 254 Score = 37.4 bits (85), Expect = 0.006 Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 8/72 (11%) Query: 36 EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEE--PGEPAGLGELGEPAGPGEPE 93 EP R P P ++ P+P + EPA P PG+PA E G P Sbjct: 165 EPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPA------EVDGNPPPA 218 Query: 94 GPGDPAAAPAEA 105 P PAA+P+ A Sbjct: 219 APEAPAASPSTA 230 Score = 37.0 bits (84), Expect = 0.008 Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 6/82 (7%) Query: 28 RRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87 +RG AASP + P+PPA + PA P A P P +P E G P Sbjct: 167 QRGPAASPPQEPSSRPPSPPAGLSTEPA-----GPGTAPRPFLPGQPAEVDGNPPPAAPE 221 Query: 88 GPGEPEGPGDPA-AAPAEAEEQ 108 P PA AAP + ++ Sbjct: 222 APAASPSTASPAPAAPGDLRQE 243 Score = 28.5 bits (62), Expect = 2.9 Identities = 33/120 (27%), Positives = 41/120 (34%), Gaps = 35/120 (29%) Query: 37 PARAPPEPAPPAEATGAPAPSRPC------------------APEPAASPAGPEEPGEPA 78 PA PA P + +P P +PC +P AS GP PGE A Sbjct: 6 PAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGP-GPGELA 64 Query: 79 GLGE-LGEPAGPGEPEG---------------PGDPAAAPAEAEEQAVEARQEEEQDLDG 122 L P P P G PG P A E + A R+ EE++ G Sbjct: 65 ARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGG 124 >gi|85815829 SH3-domain binding protein 1 [Homo sapiens] Length = 701 Score = 49.3 bits (116), Expect = 2e-06 Identities = 46/142 (32%), Positives = 57/142 (40%), Gaps = 14/142 (9%) Query: 3 APAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAE----ATGAPAPSR 58 APA A PALA+A V ASP+ R+PPE A P E T PAP+R Sbjct: 514 APAPAPAPAPALASAATKERTESEVPP-RPASPKVTRSPPETAAPVEDMARRTKRPAPAR 572 Query: 59 PCAPEP--AASPAGPEEPGEPAGLGELGEP-AGPGEPEGPG------DPAAAPAEAEEQA 109 P P P + S + P P P G G G P A P G P P + Sbjct: 573 PTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPAR 632 Query: 110 VEARQEEEQDLDGEKGPSSEGP 131 ++R+ GP+S P Sbjct: 633 RQSRRSPASPSPASPGPASPSP 654 Score = 32.3 bits (72), Expect = 0.20 Identities = 25/78 (32%), Positives = 32/78 (41%), Gaps = 10/78 (12%) Query: 32 AASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE 91 A+ P+ A P PA T APAP+ AP PA + A +E E P P Sbjct: 495 ASEELPSTAVPTPA----TTPAPAPAPAPAPAPALASAATKERTESE------VPPRPAS 544 Query: 92 PEGPGDPAAAPAEAEEQA 109 P+ P A E+ A Sbjct: 545 PKVTRSPPETAAPVEDMA 562 Score = 32.0 bits (71), Expect = 0.26 Identities = 23/81 (28%), Positives = 27/81 (33%), Gaps = 4/81 (4%) Query: 26 LVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE 85 LV A P PP P PA +P+ P P + P PA + Sbjct: 609 LVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAA 668 Query: 86 PAGPGEPEG----PGDPAAAP 102 A G PE P PA P Sbjct: 669 TAEGGAPEAISGVPTPPAIPP 689 Score = 29.3 bits (64), Expect = 1.7 Identities = 26/100 (26%), Positives = 38/100 (38%), Gaps = 3/100 (3%) Query: 12 PALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAA-SPAG 70 P AL L +R P P PP+PA ++ +PA P +P PA+ SP Sbjct: 599 PGTPQALPRRLVGSSLRAPTVPPPLPP-TPPQPA-RRQSRRSPASPSPASPGPASPSPVS 656 Query: 71 PEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAV 110 P + E P G P A P + +++ Sbjct: 657 LSNPAQVDLGAATAEGGAPEAISGVPTPPAIPPQPRPRSL 696 >gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo sapiens] Length = 305 Score = 48.9 bits (115), Expect = 2e-06 Identities = 39/129 (30%), Positives = 47/129 (36%), Gaps = 8/129 (6%) Query: 35 PEPARAP---PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE 91 P P AP P PAP A AP AP PA +PA P A PA Sbjct: 139 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 198 Query: 92 PEGPGDPAAAPAEAEEQAVEARQEEEQDL-----DGEKGPSSEGPEEEDGEGFSFKYSPG 146 P P AAP E+ EQ Q ++ L G G + G G + K G Sbjct: 199 PAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSG 258 Query: 147 KLRGNQYKK 155 L + + K Sbjct: 259 PLISDFFAK 267 Score = 43.5 bits (101), Expect = 9e-05 Identities = 42/110 (38%), Positives = 51/110 (46%), Gaps = 10/110 (9%) Query: 4 PAELLAALPALATA-----LALLLAWLLVRRGAAASPEPARAPPEPAPPAEATG-APAPS 57 P +LA PA A A +A +A ++ A +P PA AP A PA A APAP+ Sbjct: 139 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 198 Query: 58 RPCAPEPAASPAGPEEPGEPAGLGELG-EPAGPGEPEG-PGDPAAAPAEA 105 AP P A+P E G A G+ G EP G G PAA A A Sbjct: 199 PAPAPAPDAAPQESAEQG--ANQGQRGQEPLADQLHSGISGRPAAGTAAA 246 >gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo sapiens] Length = 305 Score = 48.9 bits (115), Expect = 2e-06 Identities = 39/129 (30%), Positives = 47/129 (36%), Gaps = 8/129 (6%) Query: 35 PEPARAP---PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE 91 P P AP P PAP A AP AP PA +PA P A PA Sbjct: 139 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 198 Query: 92 PEGPGDPAAAPAEAEEQAVEARQEEEQDL-----DGEKGPSSEGPEEEDGEGFSFKYSPG 146 P P AAP E+ EQ Q ++ L G G + G G + K G Sbjct: 199 PAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSG 258 Query: 147 KLRGNQYKK 155 L + + K Sbjct: 259 PLISDFFAK 267 Score = 43.5 bits (101), Expect = 9e-05 Identities = 42/110 (38%), Positives = 51/110 (46%), Gaps = 10/110 (9%) Query: 4 PAELLAALPALATA-----LALLLAWLLVRRGAAASPEPARAPPEPAPPAEATG-APAPS 57 P +LA PA A A +A +A ++ A +P PA AP A PA A APAP+ Sbjct: 139 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 198 Query: 58 RPCAPEPAASPAGPEEPGEPAGLGELG-EPAGPGEPEG-PGDPAAAPAEA 105 AP P A+P E G A G+ G EP G G PAA A A Sbjct: 199 PAPAPAPDAAPQESAEQG--ANQGQRGQEPLADQLHSGISGRPAAGTAAA 246 >gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo sapiens] Length = 316 Score = 48.9 bits (115), Expect = 2e-06 Identities = 39/129 (30%), Positives = 47/129 (36%), Gaps = 8/129 (6%) Query: 35 PEPARAP---PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE 91 P P AP P PAP A AP AP PA +PA P A PA Sbjct: 150 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 209 Query: 92 PEGPGDPAAAPAEAEEQAVEARQEEEQDL-----DGEKGPSSEGPEEEDGEGFSFKYSPG 146 P P AAP E+ EQ Q ++ L G G + G G + K G Sbjct: 210 PAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSG 269 Query: 147 KLRGNQYKK 155 L + + K Sbjct: 270 PLISDFFAK 278 Score = 43.5 bits (101), Expect = 9e-05 Identities = 42/110 (38%), Positives = 51/110 (46%), Gaps = 10/110 (9%) Query: 4 PAELLAALPALATA-----LALLLAWLLVRRGAAASPEPARAPPEPAPPAEATG-APAPS 57 P +LA PA A A +A +A ++ A +P PA AP A PA A APAP+ Sbjct: 150 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 209 Query: 58 RPCAPEPAASPAGPEEPGEPAGLGELG-EPAGPGEPEG-PGDPAAAPAEA 105 AP P A+P E G A G+ G EP G G PAA A A Sbjct: 210 PAPAPAPDAAPQESAEQG--ANQGQRGQEPLADQLHSGISGRPAAGTAAA 257 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 48.9 bits (115), Expect = 2e-06 Identities = 42/133 (31%), Positives = 50/133 (37%), Gaps = 26/133 (19%) Query: 29 RGAAASPEPARAPPEPAPPAEA--------TGAPAPSRPCAPEPAASPAGPEEPGEPAGL 80 RG P P P PP E G P P P P A GP+ P P G+ Sbjct: 1218 RGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGP--PGGI 1275 Query: 81 GELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-------EGPEE 133 G G GEP G+P P E + + E+ GE GPS +GP Sbjct: 1276 GNPGAVGEKGEPGEAGEP-GLPGEGGPPGPKGERGEK----GESGPSGAAGPPGPKGPPG 1330 Query: 134 EDGEGFSFKYSPG 146 +DG K SPG Sbjct: 1331 DDGP----KGSPG 1339 Score = 47.0 bits (110), Expect = 8e-06 Identities = 40/122 (32%), Positives = 48/122 (39%), Gaps = 14/122 (11%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89 G SP P P +P PP E P P+ P G EPG+ G GEP Sbjct: 1333 GPKGSPGPVGFPGDPGPPGE----PGPAGQDGPPGDKGDDG--EPGQTGSPGPTGEPGPS 1386 Query: 90 GEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGEGFSFKYSPGKL 148 G P G P PA E + E + E L+G G + GP+ G K P L Sbjct: 1387 GPPGKRGPP--GPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPG-----KPGPDGL 1439 Query: 149 RG 150 RG Sbjct: 1440 RG 1441 Score = 44.7 bits (104), Expect = 4e-05 Identities = 37/123 (30%), Positives = 43/123 (34%), Gaps = 16/123 (13%) Query: 30 GAAASPEPARAPPEPAP-----PAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELG 84 G P PA +P E P P G P P P P G + P PAG L Sbjct: 1078 GPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQ 1137 Query: 85 EPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGP----------SSEGPEEE 134 P G P GP P + E E Q+ + GE+GP GP Sbjct: 1138 GPVGLPGPAGPVGPPGEDGDKGEIG-EPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGA 1196 Query: 135 DGE 137 DGE Sbjct: 1197 DGE 1199 Score = 44.3 bits (103), Expect = 5e-05 Identities = 43/132 (32%), Positives = 49/132 (37%), Gaps = 18/132 (13%) Query: 22 LAWLLVRRGAAASPEPARAPPEPAPPAEA-----TGAPAPSRPCAPEPAASPAGPE---- 72 L L + G P PA P + PP G P P + P GP Sbjct: 1028 LPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAG 1087 Query: 73 EPGE--PAGL-GELGEPAGPGE--PEGPGDPAAAPAEAEEQAVEARQ--EEEQDLDGEKG 125 PGE PAG G +G P PG P GP AP E Q R + L G G Sbjct: 1088 SPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAG 1147 Query: 126 PSSEGPEEEDGE 137 P GP EDG+ Sbjct: 1148 P--VGPPGEDGD 1157 Score = 41.2 bits (95), Expect = 4e-04 Identities = 37/136 (27%), Positives = 45/136 (33%), Gaps = 42/136 (30%) Query: 30 GAAASPEPARAPPEPAPPAEA-----------------TGAPAPSRPCAPEPAASPAGPE 72 G P P+ P + PP A G P + P P+ A GP+ Sbjct: 1378 GPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPD 1437 Query: 73 E-PGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-- 129 G P +GE G P PG P+GP P P L G+ GP E Sbjct: 1438 GLRGIPGPVGEQGLPGSPG-PDGPPGPMGPPG-------------LPGLKGDSGPKGEKG 1483 Query: 130 --------GPEEEDGE 137 GP E GE Sbjct: 1484 HPGLIGLIGPPGEQGE 1499 Score = 39.7 bits (91), Expect = 0.001 Identities = 34/130 (26%), Positives = 50/130 (38%), Gaps = 16/130 (12%) Query: 41 PPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAA 100 P P P G P P P + ++ P GP+ GE G P PG P PG+ Sbjct: 1523 PSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPK--------GEAGHPGPPGPPGPPGE-VI 1573 Query: 101 APAEAEEQAVEARQEEEQDLDGEKGPS----SEGPEEEDGEGFSFKYSPGKLR---GNQY 153 P + + Q LD G + ++G EE G S K +++ G Q Sbjct: 1574 QPLPIQASRTRRNIDASQLLDDGNGENYVDYADGMEEIFGSLNSLKLEIEQMKRPLGTQQ 1633 Query: 154 KKMMTKEELE 163 T ++L+ Sbjct: 1634 NPARTCKDLQ 1643 Score = 39.3 bits (90), Expect = 0.002 Identities = 36/113 (31%), Positives = 43/113 (38%), Gaps = 18/113 (15%) Query: 36 EPARAPPEPAPPAEATGAPAPSRP------CAPEPAASPAGPEEP----GEPAGLGELGE 85 EP A EP P E G P P P AA P GP+ P G G +G Sbjct: 1286 EPGEAG-EPGLPGEG-GPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGF 1343 Query: 86 PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGE 137 P PG P PG PA + + + E G GP+ E GP G+ Sbjct: 1344 PGDPGPPGEPG-----PAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGK 1391 Score = 38.9 bits (89), Expect = 0.002 Identities = 32/103 (31%), Positives = 37/103 (35%), Gaps = 9/103 (8%) Query: 35 PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG 94 P PP P G P P GP P P+G P GP P G Sbjct: 1217 PRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGP--PGG 1274 Query: 95 PGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGE 137 G+P A + E + E L GE GP GP+ E GE Sbjct: 1275 IGNPGAVGEKG-----EPGEAGEPGLPGEGGP--PGPKGERGE 1310 Score = 37.4 bits (85), Expect = 0.006 Identities = 34/119 (28%), Positives = 41/119 (34%), Gaps = 17/119 (14%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG 88 RG P P EP P G P P P P P G+P G +G Sbjct: 663 RGDDGEVGPRGLPGEPGP----RGLLGPKGP--PGPPGPPGVTGMDGQPGPKGNVGPQGE 716 Query: 89 PGEPEGPGDPAAAPAEAEEQAVEARQEE----EQDLDGEKG-------PSSEGPEEEDG 136 PG P G+P A + A+ E+ + L G G P EGP E G Sbjct: 717 PGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKG 775 Score = 37.4 bits (85), Expect = 0.006 Identities = 33/116 (28%), Positives = 40/116 (34%), Gaps = 8/116 (6%) Query: 29 RGAAASPEPA--RAPPEPAP---PAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGEL 83 RG P P R P P P TG P P + A P G P P G Sbjct: 900 RGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGF 959 Query: 84 GEPAGPGEPEGPGDPAAAPAEAEEQAVEAR--QEEEQDLDGEKGPSSE-GPEEEDG 136 P GP P G P + E + + + G +GP+ E GP E G Sbjct: 960 PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERG 1015 Score = 36.6 bits (83), Expect = 0.011 Identities = 34/124 (27%), Positives = 43/124 (34%), Gaps = 28/124 (22%) Query: 28 RRGAAASPEPARAPPEPAPPAEA-----TGAPAPSRPCA-PEPAASPAGPEEPGEPAGLG 81 RRG A S P + P + G P P P+ P P + GE G Sbjct: 608 RRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDG 667 Query: 82 ELGEPAGPGE--------PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-GPE 132 E+G PGE P+GP P P +DG+ GP GP+ Sbjct: 668 EVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVT-------------GMDGQPGPKGNVGPQ 714 Query: 133 EEDG 136 E G Sbjct: 715 GEPG 718 Score = 36.6 bits (83), Expect = 0.011 Identities = 25/76 (32%), Positives = 28/76 (36%), Gaps = 3/76 (3%) Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG 88 +G P P P E TG + P P P GP GE +GE G P Sbjct: 963 KGPPGPPGKDGLPGHPGQRGE-TGFQGKTGPPGPPGVVGPQGPT--GETGPMGERGHPGP 1019 Query: 89 PGEPEGPGDPAAAPAE 104 PG P G P A E Sbjct: 1020 PGPPGEQGLPGLAGKE 1035 Score = 35.0 bits (79), Expect = 0.031 Identities = 24/65 (36%), Positives = 25/65 (38%), Gaps = 9/65 (13%) Query: 43 EPAPPAE-----ATGAPAPSRPCAPEPAASPAG-PEEPGEPAGLGELGEPAG---PGEPE 93 EP PP + A G P P P P G P PG P G G P PGE Sbjct: 716 EPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKG 775 Query: 94 GPGDP 98 G G P Sbjct: 776 GQGPP 780 Score = 34.3 bits (77), Expect = 0.053 Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 20/89 (22%) Query: 36 EPARAPPE--PAPPA------EATGAPAPSRPCAPEPAA--------SPAGPEEP----G 75 +P +P E P PA E G P + EPA P GPE P G Sbjct: 422 DPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPG 481 Query: 76 EPAGLGELGEPAGPGEPEGPGDPAAAPAE 104 P +G G+ PGE PG P A+ Sbjct: 482 PPGTMGPTGQVGDPGERGPPGRPGLPGAD 510 Score = 34.3 bits (77), Expect = 0.053 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 20/110 (18%) Query: 29 RGAAASPEP--ARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86 +GA P P R P P G+P P P P P P P G+ GE G P Sbjct: 1428 QGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGP--PGPMGPPGLPGLKGDSGPKGEKGHP 1485 Query: 87 AGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG 136 G PG E ++ ++ L G +G S GP+ E G Sbjct: 1486 GLIGLIGPPG--------------EQGEKGDRGLPGPQG--SSGPKGEQG 1519 Score = 33.9 bits (76), Expect = 0.069 Identities = 25/86 (29%), Positives = 33/86 (38%), Gaps = 16/86 (18%) Query: 44 PAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPA 103 PA P TG P P P P GEP +G P GP +GP PA P Sbjct: 560 PAGPMGLTGRPGPVGP--------PGSGGLKGEPGDVG----PQGPRGVQGPPGPAGKPG 607 Query: 104 EAEEQAVEARQEEEQDLDGEKGPSSE 129 + A + + + G+ GP + Sbjct: 608 ----RRGRAGSDGARGMPGQTGPKGD 629 Score = 32.7 bits (73), Expect = 0.15 Identities = 39/138 (28%), Positives = 46/138 (33%), Gaps = 24/138 (17%) Query: 28 RRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87 ++G A EP P P G P P P P P E G P G G Sbjct: 454 QKGEPAIIEPGMLIEGPPGPEGPAGLPGP--PGTMGPTGQVGDPGERGPPGRPGLPGADG 511 Query: 88 GPGEP----------EGPGD-----PAAAPAEAEEQAVEARQEEEQDLDGEKGP----SS 128 PG P G GD P + E++ QA+ Q+ L G GP Sbjct: 512 LPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAI--LQQARLALRGPAGPMGLTGR 569 Query: 129 EGPEEEDGEGFSFKYSPG 146 GP G G K PG Sbjct: 570 PGPVGPPGSG-GLKGEPG 586 Score = 32.7 bits (73), Expect = 0.15 Identities = 34/119 (28%), Positives = 42/119 (35%), Gaps = 16/119 (13%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89 GA P P A PP E P P P P P + G P G G P GP Sbjct: 727 GAQGLPGPQGAI---GPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQG-PPGP 782 Query: 90 GEPEG-PGDPAAAPAEAEEQAVEARQEEEQD----------LDGEKGP-SSEGPEEEDG 136 P G PG A+ + E+ +D + G++G GP EDG Sbjct: 783 QGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDG 841 Score = 32.3 bits (72), Expect = 0.20 Identities = 35/124 (28%), Positives = 41/124 (33%), Gaps = 10/124 (8%) Query: 17 ALALLLAWLLVRRGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEP 74 A A+L L RG A P PP G P P P P GP Sbjct: 546 AQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPA-- 603 Query: 75 GEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEE 133 G+P G G G P G + A E+ G+ GPS GP Sbjct: 604 GKPGRRGRAGSDGARGMPGQTGPKGDRGFDG-----LAGLPGEKGHRGDPGPSGPPGPPG 658 Query: 134 EDGE 137 +DGE Sbjct: 659 DDGE 662 Score = 30.4 bits (67), Expect = 0.77 Identities = 20/65 (30%), Positives = 22/65 (33%), Gaps = 5/65 (7%) Query: 46 PPAEA-----TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAA 100 PP E G P P P+ GP P P G L P GP +G P Sbjct: 1493 PPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTG 1552 Query: 101 APAEA 105 EA Sbjct: 1553 PKGEA 1557 Score = 30.0 bits (66), Expect = 1.0 Identities = 20/57 (35%), Positives = 23/57 (40%), Gaps = 6/57 (10%) Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86 G P P P P P GA S P P+ A GP PG P GE+ +P Sbjct: 1525 GPIGPPGPPGLPGPPGPK----GAKGSSGPTGPKGEAGHPGP--PGPPGPPGEVIQP 1575 Score = 29.3 bits (64), Expect = 1.7 Identities = 18/47 (38%), Positives = 19/47 (40%), Gaps = 2/47 (4%) Query: 52 GAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDP 98 G P P PE GP G+P LG GE G P PG P Sbjct: 832 GPPGPRGEDGPEGPKGRGGPN--GDPGPLGPPGEKGKLGVPGLPGYP 876 >gi|27894378 chloride intracellular channel 6 [Homo sapiens] Length = 686 Score = 48.9 bits (115), Expect = 2e-06 Identities = 43/117 (36%), Positives = 51/117 (43%), Gaps = 17/117 (14%) Query: 29 RGAAASPEPARAPPEPAPPAEATG-----APAPSRPCAPEPAASPAGPEE-------PGE 76 RGAAA E P+ P AEA G + APE A P G EE G Sbjct: 52 RGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGA 111 Query: 77 PAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPS--SEGP 131 G G GEP G + E P D AA E +E+A + + E GE G S +EGP Sbjct: 112 SPGRGAQGEPRGEAQRE-PEDSAA--PERQEEAEQRPEVPEGSASGEAGDSVDAEGP 165 Score = 38.9 bits (89), Expect = 0.002 Identities = 37/139 (26%), Positives = 54/139 (38%), Gaps = 8/139 (5%) Query: 34 SPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPE 93 +P P P PAP AE G P + A P S E P A + E G G G Sbjct: 11 APGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAG---GGGPDR 67 Query: 94 GPGDPAAAP--AEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKLRGN 151 GP A A E +A E E + G G + G ++ +G + + G+ RG Sbjct: 68 GPEAEARGTRGAHGETEAEEGAPEGAEVPQG--GEETSGAQQVEGAS-PGRGAQGEPRGE 124 Query: 152 QYKKMMTKEELEEEQRTEE 170 ++ E ++ E+ Sbjct: 125 AQREPEDSAAPERQEEAEQ 143 Score = 36.6 bits (83), Expect = 0.011 Identities = 33/118 (27%), Positives = 43/118 (36%), Gaps = 9/118 (7%) Query: 27 VRRGAAASPEPARAPPEPAPPAEATG-------APAPSRPCAPEPAASPAGPEEPGEPAG 79 V G +A P + A AE G AP +R A E +EPGE Sbjct: 313 VAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEE 372 Query: 80 LGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGE 137 E P GP E E G +P ++ +R E + + EGP E GE Sbjct: 373 RRE-RSPEGPREEEAAGGEEESP-DSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGE 428 Score = 35.8 bits (81), Expect = 0.018 Identities = 39/124 (31%), Positives = 48/124 (38%), Gaps = 22/124 (17%) Query: 37 PARAPPEPAPPA----EATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG--PG 90 PA E PA +A G +R + EP S G P A GE AG PG Sbjct: 265 PAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPG 324 Query: 91 E-----------PEGPGDPAAAPAEAEEQAVEAR-----QEEEQDLDGEKGPSSEGPEEE 134 E P G AAP +A A E R Q+E + + + S EGP EE Sbjct: 325 ELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREE 384 Query: 135 DGEG 138 + G Sbjct: 385 EAAG 388 Score = 34.7 bits (78), Expect = 0.041 Identities = 33/101 (32%), Positives = 41/101 (40%), Gaps = 23/101 (22%) Query: 65 AASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPA--------------EAEEQAV 110 A PAG E G +G+ G+P G G A PA +AE A Sbjct: 232 AEGPAGDSVDAE----GRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAG 287 Query: 111 EARQ---EEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKL 148 AR+ E +Q DG P +E E GE S SPG+L Sbjct: 288 RARRVSGEPQQSGDGSLSPQAEAIEVAAGE--SAGRSPGEL 326 Score = 33.1 bits (74), Expect = 0.12 Identities = 31/95 (32%), Positives = 39/95 (41%), Gaps = 9/95 (9%) Query: 45 APPAEATGAPAPSRPCAPEPAASPAGPEE----PGEPAG--LGELGEPAGPGEPEGPGDP 98 +P A G P PE +A+P EE P P G GE G+ P G Sbjct: 112 SPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIE 171 Query: 99 AAAPAEAEEQAVEARQEEEQDLDGEKGPS--SEGP 131 A PA +A E R + D +G G S +EGP Sbjct: 172 AEGPAGDSVEA-EGRVGDSVDAEGPAGDSVDAEGP 205 >gi|237757312 synaptojanin 1 isoform c [Homo sapiens] Length = 1295 Score = 48.1 bits (113), Expect = 4e-06 Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 4/97 (4%) Query: 37 PARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPG 96 P+RAP P A +P ++P P P PA P EP P + P P P+ P Sbjct: 1068 PSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPP 1127 Query: 97 DPAA----APAEAEEQAVEARQEEEQDLDGEKGPSSE 129 P+ AP E A ++ +D G PS + Sbjct: 1128 PPSGARSPAPTRKEFGAPKSPGTTRKDNIGRSQPSPQ 1164 Score = 42.0 bits (97), Expect = 3e-04 Identities = 36/127 (28%), Positives = 45/127 (35%), Gaps = 12/127 (9%) Query: 33 ASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPA-------GPEEPG----EPAGLG 81 A P + PP P P A T P RP P A SPA P+ PG + G Sbjct: 1100 AQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGAPKSPGTTRKDNIGRS 1159 Query: 82 ELGEPAGPGEPEGPGDPAAAPA-EAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFS 140 + AG P G A P + A Q + G P S+ E +G + Sbjct: 1160 QPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGST 1219 Query: 141 FKYSPGK 147 F P K Sbjct: 1220 FLPEPLK 1226 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.302 0.127 0.365 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,542,534 Number of Sequences: 37866 Number of extensions: 876993 Number of successful extensions: 31105 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1516 Number of HSP's successfully gapped in prelim test: 1825 Number of HSP's that attempted gapping in prelim test: 7570 Number of HSP's gapped (non-prelim): 13503 length of query: 170 length of database: 18,247,518 effective HSP length: 95 effective length of query: 75 effective length of database: 14,650,248 effective search space: 1098768600 effective search space used: 1098768600 T: 11 A: 40 X1: 17 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.7 bits) S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.