Guide to the Human Genome
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Search of human proteins with 56549129

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56549129 transmembrane anchor protein 1 isoform 3 [Homo
sapiens]
         (170 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56549129 transmembrane anchor protein 1 isoform 3 [Homo sapiens]   346   6e-96
gi|56549133 transmembrane anchor protein 1 isoform 2 [Homo sapiens]   342   1e-94
gi|56549131 transmembrane anchor protein 1 isoform 1 [Homo sapiens]   341   2e-94
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    55   3e-08
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    54   5e-08
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [...    53   1e-07
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       53   1e-07
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       53   1e-07
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    53   1e-07
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       53   1e-07
gi|23503317 coiled-coil domain containing 96 [Homo sapiens]            52   2e-07
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    52   3e-07
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    51   4e-07
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    51   4e-07
gi|24308115 interferon regulatory factor 2 binding protein 1 [Ho...    51   5e-07
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    50   7e-07
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    50   7e-07
gi|153070260 myristoylated alanine-rich protein kinase C substra...    50   7e-07
gi|32307177 forkhead box G1 [Homo sapiens]                             50   7e-07
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    50   1e-06
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    50   1e-06
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    50   1e-06
gi|194578898 hypothetical protein LOC100170841 [Homo sapiens]          49   2e-06
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                49   2e-06
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    49   2e-06
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    49   2e-06
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ...    49   2e-06
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       49   2e-06
gi|27894378 chloride intracellular channel 6 [Homo sapiens]            49   2e-06
gi|237757312 synaptojanin 1 isoform c [Homo sapiens]                   48   4e-06

>gi|56549129 transmembrane anchor protein 1 isoform 3 [Homo sapiens]
          Length = 170

 Score =  346 bits (887), Expect = 6e-96
 Identities = 170/170 (100%), Positives = 170/170 (100%)

Query: 1   MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60
           MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC
Sbjct: 1   MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60

Query: 61  APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120
           APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL
Sbjct: 61  APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120

Query: 121 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170
           DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE
Sbjct: 121 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170


>gi|56549133 transmembrane anchor protein 1 isoform 2 [Homo sapiens]
          Length = 177

 Score =  342 bits (876), Expect = 1e-94
 Identities = 168/169 (99%), Positives = 168/169 (99%)

Query: 1   MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60
           MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC
Sbjct: 1   MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60

Query: 61  APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120
           APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL
Sbjct: 61  APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120

Query: 121 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTE 169
           DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQR E
Sbjct: 121 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRIE 169


>gi|56549131 transmembrane anchor protein 1 isoform 1 [Homo sapiens]
          Length = 204

 Score =  341 bits (875), Expect = 2e-94
 Identities = 167/170 (98%), Positives = 169/170 (99%)

Query: 1   MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60
           MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC
Sbjct: 1   MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60

Query: 61  APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120
           APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL
Sbjct: 61  APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120

Query: 121 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170
           DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQR ++
Sbjct: 121 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRVQK 170


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 55.1 bits (131), Expect = 3e-08
 Identities = 43/111 (38%), Positives = 50/111 (45%), Gaps = 15/111 (13%)

Query: 31  AAASPEPARAPPEPAPPAEATGA--------PAPSRPCAPEPAASPAGPEEPGEPAGLGE 82
           A A   PA APP P PPA AT A        P  + P  P PAA+  G      PA    
Sbjct: 260 APAPAAPAAAPPPP-PPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPA 318

Query: 83  LGEPAGPGEPEGPGDPAAAP-----AEAEEQAVEARQEEEQDLDGEKGPSS 128
            G PAG     GPG  AAAP     AE+ ++ V+A     Q L    GP+S
Sbjct: 319 AGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTL-AASGPAS 368



 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 36/95 (37%), Positives = 41/95 (43%), Gaps = 9/95 (9%)

Query: 28  RRGAAASPEPARAPPEPAPPAEATGAP--APSRPCAPEPAASP--AGPEE----PGEPAG 79
           +R    SP     P  PAPPA     P    +  CAP PAA+   AGPE     P +PAG
Sbjct: 103 QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG 162

Query: 80  LGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQ 114
              L   AGPG   GPG P   P   +     A Q
Sbjct: 163 PAALAARAGPGPGPGPG-PGPGPGPGKPAGPGAAQ 196



 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 39/112 (34%), Positives = 43/112 (38%), Gaps = 39/112 (34%)

Query: 30  GAAASPEPA-RAPPEPAPPAEATGAPAPSRP-----------------------CAPEPA 65
           GAA  P PA RA P    P +  G P+P RP                       CAP PA
Sbjct: 84  GAAPEPPPAGRARPGGGGP-QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPA 142

Query: 66  A---------SPAGPEEPGEPAGLGELGEPA-----GPGEPEGPGDPAAAPA 103
           A         +PAGP +P  PA L     P      GPG   GPG PA   A
Sbjct: 143 AAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGA 194



 Score = 43.5 bits (101), Expect = 9e-05
 Identities = 47/115 (40%), Positives = 53/115 (46%), Gaps = 28/115 (24%)

Query: 1   MEAPAELLAALPALATALALLLAWLLVRRGAAAS---PEPA------RAPP---EPAPPA 48
           +   A LL +  A A A++L      V  G AA    P+PA      + PP     APPA
Sbjct: 198 LNGSAALLNSHHAAAPAVSL------VNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPA 251

Query: 49  EATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPA 103
            A    APS P AP PAA  A P  P  PA    L  P  PG P GP  P AAPA
Sbjct: 252 PA----APSPPAAPAPAAPAAAPP-PPPPAP-ATLARP--PGHPAGP--PTAAPA 296



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 22/57 (38%), Positives = 24/57 (42%), Gaps = 7/57 (12%)

Query: 44  PAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAA 100
           PA PAE     AP  P A        GP+ PG P+       P  P  P GP  PAA
Sbjct: 75  PAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPS-------PRRPLVPAGPAPPAA 124



 Score = 37.4 bits (85), Expect = 0.006
 Identities = 39/120 (32%), Positives = 42/120 (35%), Gaps = 11/120 (9%)

Query: 30  GAAASPEPAR-APPEPAPPAEAT-GAPAPSRPCAPEPAA--SPAGPEEPG---EPAGLGE 82
           G AA  E A  A PEP P   A  G   P RP  P P     PAGP  P     P   G 
Sbjct: 74  GPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGS 133

Query: 83  LGE----PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEG 138
            G     PA      GP    A PA+    A  A +       G       GP +  G G
Sbjct: 134 AGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPG 193



 Score = 33.1 bits (74), Expect = 0.12
 Identities = 37/121 (30%), Positives = 41/121 (33%), Gaps = 14/121 (11%)

Query: 3   APAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAP 62
           A  E   A PA     A L A      G    P P   P +PA P  A      +     
Sbjct: 148 AGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNS 207

Query: 63  EPAASPAGPEEPGEPAGLGELGEPAGPG------------EPEGPG--DPAAAPAEAEEQ 108
             AA+PA       PA L  L +PA PG             P  P    P AAPA A   
Sbjct: 208 HHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPA 267

Query: 109 A 109
           A
Sbjct: 268 A 268



 Score = 30.8 bits (68), Expect = 0.59
 Identities = 26/83 (31%), Positives = 29/83 (34%), Gaps = 1/83 (1%)

Query: 31  AAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPA-GLGELGEPAGP 89
           A+A+     AP  P   A A GA            A+ AGP  P E A G      PAG 
Sbjct: 35  ASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGR 94

Query: 90  GEPEGPGDPAAAPAEAEEQAVEA 112
             P G G     P       V A
Sbjct: 95  ARPGGGGPQRPGPPSPRRPLVPA 117


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 54.3 bits (129), Expect = 5e-08
 Identities = 45/150 (30%), Positives = 60/150 (40%), Gaps = 14/150 (9%)

Query: 32  AASPEPARAPPEPA--PPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89
           A +  P  +PP PA   P E   AP P  P  P P   P     P  P  L   G P G 
Sbjct: 812 APTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLP--PPQLVPEGTPGGG 869

Query: 90  GEPE----------GPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGF 139
           G P              D      E EE+  E  +EEE+D + E+    E  EEE+ E  
Sbjct: 870 GPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEE 929

Query: 140 SFKYSPGKLRGNQYKKMMTKEELEEEQRTE 169
            F+    +  G   ++   ++E EEE+  E
Sbjct: 930 EFEEEFEEEEGELEEEEEEEDEEEEEELEE 959



 Score = 51.6 bits (122), Expect = 3e-07
 Identities = 49/163 (30%), Positives = 66/163 (40%), Gaps = 31/163 (19%)

Query: 37  PARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGP--EEPGE-PAGLGELGEPAGP---- 89
           P   PP P PP      P P  P  P P ASP  P  EEP E PA  G L  P  P    
Sbjct: 792 PEGLPPLPPPPPSGA-TPPPIAPTGP-PTASPPVPAKEEPEELPAAPGPLPPPPPPPPPV 849

Query: 90  --------------GEPEGPGDPAAAP--------AEAEEQAVEARQEEEQDLDGEKGPS 127
                         G P G G PA           +  EE+  E  +EEE++ + E+   
Sbjct: 850 PGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEED 909

Query: 128 SEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170
            E  EE++ E F  +    +    ++++   + E EEE+  EE
Sbjct: 910 FEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEE 952



 Score = 33.9 bits (76), Expect = 0.069
 Identities = 18/55 (32%), Positives = 22/55 (40%), Gaps = 4/55 (7%)

Query: 34  SPEPARAPP----EPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELG 84
           +P P RAPP     P P   +  +  P     P P+A P     PG P     LG
Sbjct: 656 APSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLG 710



 Score = 33.9 bits (76), Expect = 0.069
 Identities = 41/149 (27%), Positives = 53/149 (35%), Gaps = 20/149 (13%)

Query: 30   GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASP-AGPEEPGEPAGLGELGEPAG 88
            G A       APP P  P           P  P P + P   PE   EP  L E+ EP  
Sbjct: 966  GTAGGEVEEGAPPPPTLP-----------PALPPPESPPKVQPEPEPEPGLLLEVEEPGT 1014

Query: 89   PGEPEGPGDPAAAPAEAEEQAVEARQEEE-------QDLDGEKGPSSEGPEEEDGEGFSF 141
              E      P  AP     Q    R+ E        Q+L  E+  +     EE+ E  S 
Sbjct: 1015 EEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSD 1074

Query: 142  KYSPGKLRGNQYKKMMTKEELEEEQRTEE 170
            K  P      + ++M T+ E E  Q  E+
Sbjct: 1075 KVQPPPETPAE-EEMETETEAEALQEKEQ 1102



 Score = 30.8 bits (68), Expect = 0.59
 Identities = 36/132 (27%), Positives = 40/132 (30%), Gaps = 39/132 (29%)

Query: 27   VRRGAAASPE--PARAPPEPAPPAEATGAPAP-------------------SRPCAPEPA 65
            V  GA   P   PA  PPE  P  +    P P                   +   APE  
Sbjct: 972  VEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEAL 1031

Query: 66   ASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD---------------PAAAPAEAE---E 107
             S    E  GE    G   +     EP  P                 P   PAE E   E
Sbjct: 1032 PSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETE 1091

Query: 108  QAVEARQEEEQD 119
               EA QE+EQD
Sbjct: 1092 TEAEALQEKEQD 1103



 Score = 26.9 bits (58), Expect = 8.5
 Identities = 24/71 (33%), Positives = 25/71 (35%), Gaps = 13/71 (18%)

Query: 37  PARAPPEPAPPAEATG---APAPSRPCAPEPAAS---PAGPEEPGEPAGLGELGEPAGPG 90
           P    P P PP EA     AP P  P  P P+      AGP     P         AGP 
Sbjct: 643 PTCPTPAPVPPPEAPSPFRAP-PFHPPGPMPSVGSMPSAGPMPSAGPM------PSAGPV 695

Query: 91  EPEGPGDPAAA 101
               PG P  A
Sbjct: 696 PSARPGPPTTA 706


>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo
            sapiens]
          Length = 1584

 Score = 53.1 bits (126), Expect = 1e-07
 Identities = 36/96 (37%), Positives = 42/96 (43%), Gaps = 4/96 (4%)

Query: 32   AASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPA--GLGELGEPAG- 88
            A SP P+R PP   PP      P P  P  P P   P  P    EPA   LG+ GEPA  
Sbjct: 1390 ARSP-PSRQPPSGGPPEAPPAQPPPPPPPPPPPPQQPLPPPPNLEPAPPSLGDPGEPAAH 1448

Query: 89   PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEK 124
            PG   GP       A     ++E R+    +LD EK
Sbjct: 1449 PGPSTGPSTKNENVATLSVSSLERRKSRYAELDFEK 1484


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 53.1 bits (126), Expect = 1e-07
 Identities = 40/131 (30%), Positives = 47/131 (35%), Gaps = 31/131 (23%)

Query: 26  LVRRGAAASPEPARAPPE--------------PAPPAEATGAPAPSRPCAPEPAASPAGP 71
           LVR   + +P PAR  P               P PP   +    PS    P P     GP
Sbjct: 756 LVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPE--PPPLDESPGP 813

Query: 72  EEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGP 131
           +E         L EPAGP EP GP  PA   ++ EE+              E GP    P
Sbjct: 814 KEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEE--------------EPGPEGTPP 859

Query: 132 EE-EDGEGFSF 141
                GEG  F
Sbjct: 860 SRGSSGEGLPF 870



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 5/83 (6%)

Query: 34  SPEPARAPPEPAPPAEATGAPAPSRPCAPEPA--ASPAGPEEPGEPAGLGELGEPAGPGE 91
           SPEP   PP    P    GA  P R    EPA  + P GP  P  PA   E  EP   G 
Sbjct: 801 SPEP---PPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGT 857

Query: 92  PEGPGDPAAAPAEAEEQAVEARQ 114
           P   G        AEE  +  +Q
Sbjct: 858 PPSRGSSGEGLPFAEEGNLTIKQ 880



 Score = 41.6 bits (96), Expect = 3e-04
 Identities = 31/82 (37%), Positives = 35/82 (42%), Gaps = 14/82 (17%)

Query: 31   AAASPEPARAPPEP----APPAEATGAPAPSR--------PCAPEPAASPAGPEEPGEPA 78
            A+A+P PA   P P    +PPA +   P PS         P AP PA  P  P  PG   
Sbjct: 930  ASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPG--P 987

Query: 79   GLGELGEPAGPGEPEGPGDPAA 100
            GL         GE E P  PAA
Sbjct: 988  GLESSAASRWNGETEPPAAPAA 1009



 Score = 34.3 bits (77), Expect = 0.053
 Identities = 41/146 (28%), Positives = 56/146 (38%), Gaps = 18/146 (12%)

Query: 2   EAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPA-PSRPC 60
           E PA    A P L T     L+  L    A   PEP   PP  +P  E+ GA +  S   
Sbjct: 573 EGPA---TAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHS 629

Query: 61  APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120
             +PA  P+G    G+P+   E   P G   P  P   ++ P +     V         +
Sbjct: 630 QEQPAPQPSG----GDPSPPQERNLPEGTERP--PKLCSSLPGQGPPPYV--------FM 675

Query: 121 DGEKGPSSEGPEEEDGEGFSFKYSPG 146
             +  PSS  P    G  ++F Y  G
Sbjct: 676 YPQGSPSSPAPGPPPGAPWAFSYLAG 701



 Score = 30.4 bits (67), Expect = 0.77
 Identities = 25/84 (29%), Positives = 31/84 (36%), Gaps = 4/84 (4%)

Query: 33  ASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAG---LGELGEPAGP 89
           A P     PP PA PA  T    P  P    P+   +G   P    G   + +  +PAGP
Sbjct: 829 AGPSEPPGPPAPAGPASDTEEEEPG-PEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGP 887

Query: 90  GEPEGPGDPAAAPAEAEEQAVEAR 113
              E P  P       E   V+ R
Sbjct: 888 PPRETPVPPGLDFNLTESDTVKRR 911



 Score = 28.5 bits (62), Expect = 2.9
 Identities = 21/63 (33%), Positives = 24/63 (38%), Gaps = 5/63 (7%)

Query: 35  PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG--PGEP 92
           P+ + + P P PP    GAP      A  PA  P  P        L   G   G   GE 
Sbjct: 677 PQGSPSSPAPGPPP---GAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEA 733

Query: 93  EGP 95
           EGP
Sbjct: 734 EGP 736


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 53.1 bits (126), Expect = 1e-07
 Identities = 40/131 (30%), Positives = 47/131 (35%), Gaps = 31/131 (23%)

Query: 26  LVRRGAAASPEPARAPPE--------------PAPPAEATGAPAPSRPCAPEPAASPAGP 71
           LVR   + +P PAR  P               P PP   +    PS    P P     GP
Sbjct: 838 LVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPE--PPPLDESPGP 895

Query: 72  EEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGP 131
           +E         L EPAGP EP GP  PA   ++ EE+              E GP    P
Sbjct: 896 KEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEE--------------EPGPEGTPP 941

Query: 132 EE-EDGEGFSF 141
                GEG  F
Sbjct: 942 SRGSSGEGLPF 952



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 5/83 (6%)

Query: 34  SPEPARAPPEPAPPAEATGAPAPSRPCAPEPA--ASPAGPEEPGEPAGLGELGEPAGPGE 91
           SPEP   PP    P    GA  P R    EPA  + P GP  P  PA   E  EP   G 
Sbjct: 883 SPEP---PPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGT 939

Query: 92  PEGPGDPAAAPAEAEEQAVEARQ 114
           P   G        AEE  +  +Q
Sbjct: 940 PPSRGSSGEGLPFAEEGNLTIKQ 962



 Score = 41.6 bits (96), Expect = 3e-04
 Identities = 31/82 (37%), Positives = 35/82 (42%), Gaps = 14/82 (17%)

Query: 31   AAASPEPARAPPEP----APPAEATGAPAPSR--------PCAPEPAASPAGPEEPGEPA 78
            A+A+P PA   P P    +PPA +   P PS         P AP PA  P  P  PG   
Sbjct: 1012 ASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPG--P 1069

Query: 79   GLGELGEPAGPGEPEGPGDPAA 100
            GL         GE E P  PAA
Sbjct: 1070 GLESSAASRWNGETEPPAAPAA 1091



 Score = 34.3 bits (77), Expect = 0.053
 Identities = 41/146 (28%), Positives = 56/146 (38%), Gaps = 18/146 (12%)

Query: 2   EAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPA-PSRPC 60
           E PA    A P L T     L+  L    A   PEP   PP  +P  E+ GA +  S   
Sbjct: 655 EGPA---TAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHS 711

Query: 61  APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120
             +PA  P+G    G+P+   E   P G   P  P   ++ P +     V         +
Sbjct: 712 QEQPAPQPSG----GDPSPPQERNLPEGTERP--PKLCSSLPGQGPPPYV--------FM 757

Query: 121 DGEKGPSSEGPEEEDGEGFSFKYSPG 146
             +  PSS  P    G  ++F Y  G
Sbjct: 758 YPQGSPSSPAPGPPPGAPWAFSYLAG 783



 Score = 30.4 bits (67), Expect = 0.77
 Identities = 25/84 (29%), Positives = 31/84 (36%), Gaps = 4/84 (4%)

Query: 33  ASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAG---LGELGEPAGP 89
           A P     PP PA PA  T    P  P    P+   +G   P    G   + +  +PAGP
Sbjct: 911 AGPSEPPGPPAPAGPASDTEEEEPG-PEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGP 969

Query: 90  GEPEGPGDPAAAPAEAEEQAVEAR 113
              E P  P       E   V+ R
Sbjct: 970 PPRETPVPPGLDFNLTESDTVKRR 993



 Score = 28.5 bits (62), Expect = 2.9
 Identities = 21/63 (33%), Positives = 24/63 (38%), Gaps = 5/63 (7%)

Query: 35  PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG--PGEP 92
           P+ + + P P PP    GAP      A  PA  P  P        L   G   G   GE 
Sbjct: 759 PQGSPSSPAPGPPP---GAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEA 815

Query: 93  EGP 95
           EGP
Sbjct: 816 EGP 818


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 52.8 bits (125), Expect = 1e-07
 Identities = 39/101 (38%), Positives = 51/101 (50%), Gaps = 6/101 (5%)

Query: 70   GPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE 129
            G EE GE  G  E GE  G GE EG G+      E EE+  E   EEE   +GE+    E
Sbjct: 948  GEEEEGEWEGEEEEGE--GEGEEEGEGEGEEGEGEGEEEEGEGEGEEE---EGEEEGEEE 1002

Query: 130  GPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170
            G  EE+GEG   +   G++ G + +    + E EEE+  EE
Sbjct: 1003 GEGEEEGEGEGEEEEEGEVEG-EVEGEEGEGEGEEEEGEEE 1042



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 37/100 (37%), Positives = 47/100 (47%), Gaps = 5/100 (5%)

Query: 73  EPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDG-EKGPSSEGP 131
           E GE  G  E GE  G  E EG G+      E EE+     +EEE +  G E+G   EG 
Sbjct: 872 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGE 931

Query: 132 -EEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170
            EEE+GEG   +   G+  G + +     EE E E   EE
Sbjct: 932 GEEEEGEG---EGEDGEGEGEEEEGEWEGEEEEGEGEGEE 968



 Score = 44.3 bits (103), Expect = 5e-05
 Identities = 38/109 (34%), Positives = 51/109 (46%), Gaps = 12/109 (11%)

Query: 72  EEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQE-EEQDLDGE------K 124
           EE GE  G  E GE  G  E EG G+      + EE+  E   E EE++ +GE      +
Sbjct: 888 EEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGE 947

Query: 125 GPSSEGP---EEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170
           G   EG    EEE+GEG   +   G+  G + +    +EE E E   EE
Sbjct: 948 GEEEEGEWEGEEEEGEGEGEEEGEGE--GEEGEGEGEEEEGEGEGEEEE 994



 Score = 43.9 bits (102), Expect = 7e-05
 Identities = 37/104 (35%), Positives = 47/104 (45%), Gaps = 3/104 (2%)

Query: 70   GPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQE-EEQDLDGEKGPSS 128
            G EE GE  G  E GE  G  E EG  +      E EE  VE   E EE + +GE+    
Sbjct: 981  GEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGE 1040

Query: 129  EGPEE--EDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170
            E  EE  ++GEG   + +  +    + K   T EE  E Q  EE
Sbjct: 1041 EEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEE 1084



 Score = 40.4 bits (93), Expect = 7e-04
 Identities = 34/100 (34%), Positives = 47/100 (47%), Gaps = 6/100 (6%)

Query: 70   GPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAV-EARQEEEQDLDGE-KGPS 127
            G  E  E  G GE  E  G GE E   +      E EE+   E  +EEE +++GE +G  
Sbjct: 970  GEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEE 1029

Query: 128  SEGP-EEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQ 166
             EG  EEE+GE    +    +  G   +    +EE EEE+
Sbjct: 1030 GEGEGEEEEGEE---EGEEREKEGEGEENRRNREEEEEEE 1066



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 40/111 (36%), Positives = 50/111 (45%), Gaps = 18/111 (16%)

Query: 69  AGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEA----RQEEEQDLDGE- 123
           AG EE GE  G    GE     E EG G+      E E   VE     R+EEE++ +GE 
Sbjct: 781 AGKEEKGEEEGDQGEGEEE---ETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEE 837

Query: 124 ---KGPSSEGP-EEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170
              +G   EG  EEE+GEG       G+  G + +     EE E E   EE
Sbjct: 838 EEGEGEEEEGEGEEEEGEG------KGEEEGEEGEGEEEGEEGEGEGEEEE 882



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 37/104 (35%), Positives = 49/104 (47%), Gaps = 12/104 (11%)

Query: 72   EEPGEPAGLGELGEPAGPGEP-----EGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGP 126
            EE GE  G  E GE  G GE      EG G+      E E+   E  +EEE + +GE+  
Sbjct: 905  EEEGEGEGEEEEGE--GKGEEEGEEGEGEGEEEEGEGEGEDGEGEG-EEEEGEWEGEE-E 960

Query: 127  SSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170
              EG  EE+GEG   +   G+  G + +     EE E E+  EE
Sbjct: 961  EGEGEGEEEGEG---EGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 8/100 (8%)

Query: 70  GPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEE---EQDLDGEKGP 126
           G EE G+     E  E  G G+ EG G+      E EE   E ++EE   +++   E+G 
Sbjct: 738 GEEEEGDRE---EEEEKEGEGKEEGEGEEVEGEREKEEG--ERKKEERAGKEEKGEEEGD 792

Query: 127 SSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQ 166
             EG EEE       K   G++ G + ++   + E EEE+
Sbjct: 793 QGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEE 832



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 35/101 (34%), Positives = 48/101 (47%), Gaps = 4/101 (3%)

Query: 72  EEPGEPAGLGELGEPAGPGEPEGP-GDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEG 130
           EE GE  G GE+ E  G  E E   G+      E EE+  E  +EE +    E+G   EG
Sbjct: 809 EEGGEVEG-GEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEG 867

Query: 131 PEE-EDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170
            EE E+GEG   +   G+  G +  +   +EE  E +  EE
Sbjct: 868 EEEGEEGEG-EGEEEEGEGEGEEEGEGEGEEEEGEGEGEEE 907



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 36/107 (33%), Positives = 48/107 (44%), Gaps = 8/107 (7%)

Query: 70  GPEEPGE---PAGLGELGEPAGPGEPEGP---GDPAAAPAEAEEQAVEARQEEEQDLDGE 123
           G EE GE     G GE  E  G GE EG    G+      E E +  E   E E++ +GE
Sbjct: 835 GEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGE 894

Query: 124 -KGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTE 169
            +    EG  EE+GEG   +   G+ +G +  +    E  EEE   E
Sbjct: 895 GEEEEGEGEGEEEGEG-EGEEEEGEGKGEEEGEEGEGEGEEEEGEGE 940



 Score = 34.7 bits (78), Expect = 0.041
 Identities = 36/110 (32%), Positives = 50/110 (45%), Gaps = 16/110 (14%)

Query: 72   EEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGP 131
            EE GE  G  E  E  G GE E  G+      E E +  E R+  E++ + E+G   E  
Sbjct: 1016 EEEGEVEGEVEGEEGEGEGEEE-EGEEEGEEREKEGEGEENRRNREEE-EEEEGKYQETG 1073

Query: 132  EEE----DGEGF--------SFKYSPGKLRGNQYKKMMTKEELEEEQRTE 169
            EEE    DGE +        S KY  GK +  Q K +   +   +EQR++
Sbjct: 1074 EEENERQDGEEYKKVSKIKGSVKY--GKHKTYQKKSVTNTQGNGKEQRSK 1121



 Score = 30.4 bits (67), Expect = 0.77
 Identities = 33/117 (28%), Positives = 47/117 (40%), Gaps = 24/117 (20%)

Query: 73  EPGEP-AGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQE---------------- 115
           E GE   G GE+  P G GE E          + EEQ  + R++                
Sbjct: 675 EKGEKDKGRGEMERP-GEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEE 733

Query: 116 -----EEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMT-KEELEEEQ 166
                EE++ D E+    EG  +E+GEG   +    K  G + K+    KEE  EE+
Sbjct: 734 EHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE 790



 Score = 28.9 bits (63), Expect = 2.2
 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 4/71 (5%)

Query: 104 EAEEQAVEARQEEEQDLDGEK---GPSSEGP-EEEDGEGFSFKYSPGKLRGNQYKKMMTK 159
           E EE+  +  +EEE++ +G++   G   EG  E+E+GE    + +  + +G +       
Sbjct: 737 EGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEG 796

Query: 160 EELEEEQRTEE 170
           EE E E R EE
Sbjct: 797 EEEETEGRGEE 807


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 52.8 bits (125), Expect = 1e-07
 Identities = 46/129 (35%), Positives = 52/129 (40%), Gaps = 25/129 (19%)

Query: 30  GAAASPEPARAPPEP--------APPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLG 81
           G  A+  P   PP+P                  A  RP AP PAA  A P  PG PA  G
Sbjct: 56  GLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAG 115

Query: 82  ELGEPAGPGEPEGPGDPAAAPAEA---------EEQAVEARQEEEQDLDGEKGPS----S 128
              EP G  EP GP DP AA  E          EE A   R+E+E   + +  P      
Sbjct: 116 P--EPVGTQEP-GP-DPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRD 171

Query: 129 EGPEEEDGE 137
           E  EEED E
Sbjct: 172 EPEEEEDDE 180



 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 38/108 (35%), Positives = 49/108 (45%), Gaps = 16/108 (14%)

Query: 29  RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG 88
           RG  A+P PA    +P  P    GAPA      PE    P G +EPG P  +    E A 
Sbjct: 90  RGRPAAPAPAALVAQPGAP----GAPAD---AGPE----PVGTQEPG-PDPIAAAVETA- 136

Query: 89  PGEPEGPGDPAAAPAEAEEQ-AVEARQEEEQDLDGEKGPSSEGPEEED 135
           P    GP + AAA    E++ A EA+ E  +    E  P  E  +E+D
Sbjct: 137 PAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDE--PEEEEDDEDD 182



 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 30/100 (30%), Positives = 38/100 (38%), Gaps = 1/100 (1%)

Query: 27   VRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86
            V+   A  P+PA  PP+P  P +    P P+ P  P     P  P +P  P       +P
Sbjct: 932  VQNMRATPPQPA-LPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQP 990

Query: 87   AGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGP 126
              P +P  P  P        EQA  A     Q L G   P
Sbjct: 991  VLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAP 1030



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 50/187 (26%), Positives = 64/187 (34%), Gaps = 34/187 (18%)

Query: 1    MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60
            M  P  +L   PAL      L   L  +   AA+P        PAP A    A  P+ P 
Sbjct: 985  MLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPV 1044

Query: 61   APEPAASPAGPEE---------PGEPAGLGELG--------------EPAGPGEPEGPGD 97
             P    SP  PE          P  P+ L  +                PA P  P GPG 
Sbjct: 1045 PPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPG- 1103

Query: 98   PAAAPAEAEEQAVEARQEEEQDLDGEKG-----PSSEGPEEEDGEGFSFK----YSPGKL 148
              A+P    +  VE  QEE+   D   G      S  G +   G+  S      +  G+L
Sbjct: 1104 -IASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTSGKELSDSCEGAFGGGRL 1162

Query: 149  RGNQYKK 155
             G   +K
Sbjct: 1163 EGRAARK 1169



 Score = 37.0 bits (84), Expect = 0.008
 Identities = 29/75 (38%), Positives = 34/75 (45%), Gaps = 6/75 (8%)

Query: 29   RGAAASPEPARAP-PEPAP----PAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGEL 83
            R A+A  EP   P PEP+P    P  A G PAP  P A   A S A  + P  P G    
Sbjct: 1466 RDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAA-VGAVSLATSQLPSPPLGPTVP 1524

Query: 84   GEPAGPGEPEGPGDP 98
             +P    E +G G P
Sbjct: 1525 PQPPSALESDGEGPP 1539



 Score = 35.4 bits (80), Expect = 0.024
 Identities = 28/76 (36%), Positives = 30/76 (39%), Gaps = 6/76 (7%)

Query: 32   AASPEPARAPPEPAPPAEATGAPAPS-RPCAPEPAASPAGPEEPGEPAGLGELGEPAGPG 90
            AAS   A AP EP PP     AP PS     P+PA     P  P    G   L     P 
Sbjct: 1462 AASTRDASAPREPLPPP----APEPSPHSGTPQPALGQPAPLLPA-AVGAVSLATSQLPS 1516

Query: 91   EPEGPGDPAAAPAEAE 106
             P GP  P   P+  E
Sbjct: 1517 PPLGPTVPPQPPSALE 1532



 Score = 33.9 bits (76), Expect = 0.069
 Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 8/63 (12%)

Query: 32   AASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE 91
            A    P  APP P  P+      +P     P+  A+PA    P EPA  G   +  GPG 
Sbjct: 1371 AGPSNPPGAPPAPLAPS------SPPVTALPQDGAAPATSTMP-EPAS-GTASQAGGPGT 1422

Query: 92   PEG 94
            P+G
Sbjct: 1423 PQG 1425



 Score = 29.6 bits (65), Expect = 1.3
 Identities = 20/66 (30%), Positives = 23/66 (34%)

Query: 37  PARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPG 96
           P  A P P P   A     P +P  P      A   + G PA L  L  P  P +P    
Sbjct: 732 PPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQV 791

Query: 97  DPAAAP 102
            P   P
Sbjct: 792 PPQMPP 797



 Score = 29.6 bits (65), Expect = 1.3
 Identities = 29/116 (25%), Positives = 41/116 (35%), Gaps = 18/116 (15%)

Query: 24   WLLVRRGAAASPEPARAPPEPAPPAEATG-APAPSRPCAP--EPAASPAGPEEPGEPAGL 80
            W ++      +  PA   PE +PP   +   P  S+  AP  +  +S   P        L
Sbjct: 1312 WFII---CPVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLL 1368

Query: 81   GELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG 136
             + G    PG P  P  P++ P  A  Q            DG    +S  PE   G
Sbjct: 1369 SQAGPSNPPGAPPAPLAPSSPPVTALPQ------------DGAAPATSTMPEPASG 1412



 Score = 29.3 bits (64), Expect = 1.7
 Identities = 18/60 (30%), Positives = 23/60 (38%), Gaps = 6/60 (10%)

Query: 73  EPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPE 132
           EPG  AG      PAG  EP                 VE+ QEE   L+  + P  + P+
Sbjct: 16  EPGRGAG------PAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQ 69


>gi|23503317 coiled-coil domain containing 96 [Homo sapiens]
          Length = 555

 Score = 52.0 bits (123), Expect = 2e-07
 Identities = 48/150 (32%), Positives = 69/150 (46%), Gaps = 26/150 (17%)

Query: 30  GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89
           G      PA   PEP  PAE  GA  P++P   EP A   GPEE    AG  EL + A  
Sbjct: 83  GPGEPGRPAEPQPEPEEPAEV-GAEEPAQP---EPGA---GPEELEAEAGAEELEQAAEG 135

Query: 90  GEPEGPG---------DPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFS 140
            E              + AAA  EAE + VE  +E++++   +   S    +E DGEG  
Sbjct: 136 KEVRFQASLPLTRIDEEEAAAAPEAETERVEGEEEDKEETQRDGAES----KERDGEG-- 189

Query: 141 FKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170
               P K +  + K++  ++E E+ + +EE
Sbjct: 190 ---RPAKSQ-EEGKRLYGRDEFEDLEWSEE 215



 Score = 41.2 bits (95), Expect = 4e-04
 Identities = 31/107 (28%), Positives = 37/107 (34%), Gaps = 5/107 (4%)

Query: 32  AASPEPARA---PPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGL--GELGEP 86
           AA P   +A   PP    P E    P              A  E+   P GL   E    
Sbjct: 22  AARPSKIKASSGPPTSPEPGELESEPEEEEEEQAASQGGTAADEQAEAPKGLTAAEAAGE 81

Query: 87  AGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEE 133
            GPGEP  P +P   P E  E   E   + E     E+  +  G EE
Sbjct: 82  EGPGEPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELEAEAGAEE 128



 Score = 40.4 bits (93), Expect = 7e-04
 Identities = 43/142 (30%), Positives = 56/142 (39%), Gaps = 6/142 (4%)

Query: 30  GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89
           G   SPEP     EP    E   A +     A E A +P G     E AG    GEP  P
Sbjct: 33  GPPTSPEPGELESEPEEEEEEQAA-SQGGTAADEQAEAPKGLTA-AEAAGEEGPGEPGRP 90

Query: 90  GEPE-GPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKL 148
            EP+  P +PA   AE   Q       EE  L+ E G + E  +  +G+   F+ S    
Sbjct: 91  AEPQPEPEEPAEVGAEEPAQPEPGAGPEE--LEAEAG-AEELEQAAEGKEVRFQASLPLT 147

Query: 149 RGNQYKKMMTKEELEEEQRTEE 170
           R ++ +     E   E    EE
Sbjct: 148 RIDEEEAAAAPEAETERVEGEE 169



 Score = 28.9 bits (63), Expect = 2.2
 Identities = 32/119 (26%), Positives = 41/119 (34%), Gaps = 5/119 (4%)

Query: 52  GAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVE 111
           G    S    P    + +GP    EP   GEL   + P E E     +     A+EQA  
Sbjct: 15  GGDGESLAARPSKIKASSGPPTSPEP---GEL--ESEPEEEEEEQAASQGGTAADEQAEA 69

Query: 112 ARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170
            +     +  GE+GP   G   E           G     Q +     EELE E   EE
Sbjct: 70  PKGLTAAEAAGEEGPGEPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELEAEAGAEE 128


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 51.6 bits (122), Expect = 3e-07
 Identities = 39/117 (33%), Positives = 47/117 (40%), Gaps = 15/117 (12%)

Query: 28  RRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87
           R G +    PA  PP P PPA     P P  P AP P   PA P+ P     L    E A
Sbjct: 9   RPGESPGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEALPP--EAA 66

Query: 88  GPGEPEG-----------PGDP-AAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPE 132
             G P G           PG P AA+ A+        R E +    G +GP + GP+
Sbjct: 67  DEGGPRGRLRSRDSSCGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGP-ARGPK 122



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 35/88 (39%), Positives = 37/88 (42%), Gaps = 11/88 (12%)

Query: 26  LVRRGAAASPEPARAPPEPAPPAEATGAPAPSR-----PCAPEPAASPAGPEEPGEPAGL 80
           LVRR     P PA A P P PPA   GAPA  R     P    PAA  AGP  P     L
Sbjct: 757 LVRR-PPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPAR--RL 813

Query: 81  GELGEP---AGPGEPEGPGDPAAAPAEA 105
                P   + P  P G   PAA+   A
Sbjct: 814 SRASRPLSASQPSLPHGAPGPAASTRPA 841



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 35/100 (35%), Positives = 43/100 (43%), Gaps = 13/100 (13%)

Query: 4   PAELLAALPALATALALL----LAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRP 59
           P ++ +A+  L  A A+     +A  LV   A  SP   R PP P P      APA + P
Sbjct: 720 PPQVTSAIATLQQAAAMSFCPQVARPLVGPLALGSPRLVRRPP-PGP------APAAASP 772

Query: 60  CAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPA 99
             P PA+ P  P  P  P      G PA P    GP  PA
Sbjct: 773 GPPPPASPPGAPASPRAPRTSPYGGLPAAP--LAGPALPA 810



 Score = 37.0 bits (84), Expect = 0.008
 Identities = 31/98 (31%), Positives = 39/98 (39%), Gaps = 13/98 (13%)

Query: 47  PAEATGA-PAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPG--EPEGPGDPAAAPA 103
           P E+ GA PAP  P  P PA     P  P  PA       P GPG   P+ P    A P 
Sbjct: 10  PGESPGATPAPGPPPPPPPAPPQQQPPPPPPPA------PPPGPGPAPPQHPPRAEALPP 63

Query: 104 EAEEQAVEARQEEEQDLD----GEKGPSSEGPEEEDGE 137
           EA ++     +   +D      G  G +S      +GE
Sbjct: 64  EAADEGGPRGRLRSRDSSCGRPGTPGAASTAKGSPNGE 101



 Score = 36.2 bits (82), Expect = 0.014
 Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 1/81 (1%)

Query: 46  PPAEATGAPAPSRPCAP-EPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAE 104
           P A +T   +P+  C   EP  SPAGPE P     +      A  G   GPG    A +E
Sbjct: 88  PGAASTAKGSPNGECGRGEPQCSPAGPEGPARGPKVSFSCRGAASGPAPGPGPAEEAGSE 147

Query: 105 AEEQAVEARQEEEQDLDGEKG 125
               A E R  +   +  + G
Sbjct: 148 EAGPAGEPRGSQASFMQRQFG 168



 Score = 34.3 bits (77), Expect = 0.053
 Identities = 31/98 (31%), Positives = 38/98 (38%), Gaps = 17/98 (17%)

Query: 12  PALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGP 71
           P + +A+A L      ++ AA S  P  A P   P A  +       P  P PAA+  GP
Sbjct: 721 PQVTSAIATL------QQAAAMSFCPQVARPLVGPLALGSPRLVRRPPPGPAPAAASPGP 774

Query: 72  EEPGEPAGLGELGEPAGPGEPEG------PGDPAAAPA 103
             P  P      G PA P  P        P  P A PA
Sbjct: 775 PPPASPP-----GAPASPRAPRTSPYGGLPAAPLAGPA 807



 Score = 31.2 bits (69), Expect = 0.45
 Identities = 23/66 (34%), Positives = 24/66 (36%), Gaps = 9/66 (13%)

Query: 30  GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89
           G     EP  +P  P  PA         R  A  PA  P   EE G         E AGP
Sbjct: 100 GECGRGEPQCSPAGPEGPARGPKVSFSCRGAASGPAPGPGPAEEAG--------SEEAGP 151

Query: 90  -GEPEG 94
            GEP G
Sbjct: 152 AGEPRG 157


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 51.2 bits (121), Expect = 4e-07
 Identities = 42/128 (32%), Positives = 51/128 (39%), Gaps = 22/128 (17%)

Query: 30  GAAASPEPARAPPEPAPP--------------AEATGAPAPSRPCAPEPAASPAGPE-EP 74
           G   SP PA A   P                 A A G P P  P  P+ A  P GP+ + 
Sbjct: 396 GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT 455

Query: 75  GEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL-----DGEKG-PSS 128
           GEP   G  GE    GEP GP  P  AP  A E+     + E   +      GE+G P +
Sbjct: 456 GEPGIAGFKGEQGPKGEP-GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGN 514

Query: 129 EGPEEEDG 136
            G   +DG
Sbjct: 515 RGFPGQDG 522



 Score = 44.7 bits (104), Expect = 4e-05
 Identities = 38/113 (33%), Positives = 46/113 (40%), Gaps = 11/113 (9%)

Query: 30   GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGEPAG 88
            GAA    P  +   P PP    G P PS    P+ A   +GP    GEP   G  G P  
Sbjct: 900  GAAGRVGPPGSNGNPGPP----GPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGE 955

Query: 89   PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137
             GEP G   P+ A      Q + A Q     L G++G    P   GP  E G+
Sbjct: 956  KGEP-GDDGPSGAEGPPGPQGL-AGQRGIVGLPGQRGERGFPGLPGPSGEPGK 1006



 Score = 43.9 bits (102), Expect = 7e-05
 Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 13/104 (12%)

Query: 44  PAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD--PAAA 101
           P  P    G P P+   AP P      P EPGEP   G +G    PG P  PGD   A  
Sbjct: 202 PMGPMGPRGPPGPAG--APGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGK 259

Query: 102 PAEAEEQAVEARQEEE-----QDLDGEKG----PSSEGPEEEDG 136
           P +A E+     Q          L G KG    P  +G + E G
Sbjct: 260 PGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAG 303



 Score = 42.7 bits (99), Expect = 1e-04
 Identities = 40/149 (26%), Positives = 50/149 (33%), Gaps = 42/149 (28%)

Query: 29  RGAAASPEPARAPPEPAPPAEATGAPA-------------------------PSRPCAPE 63
           RG    P PA  PP P  PA   G P                          P  P +P 
Sbjct: 344 RGNDGQPGPA-GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPG 402

Query: 64  PAASPAGPEEPGEPAGLGELGEPA-----------GPGEPEGPGDPAAAPAEAEEQAVEA 112
           PA +   P   G P   G  G P            GP  P+G   P     +  E  + A
Sbjct: 403 PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI-A 461

Query: 113 RQEEEQDLDGEKGPS----SEGPEEEDGE 137
             + EQ   GE GP+    + GP  E+G+
Sbjct: 462 GFKGEQGPKGEPGPAGPQGAPGPAGEEGK 490



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 35/116 (30%), Positives = 43/116 (37%), Gaps = 9/116 (7%)

Query: 29  RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPE------PAASPAGPEEPGEPAGLGE 82
           +G   +P P     EP  P    G P P  P  P        A    G +E    A LG 
Sbjct: 140 KGEKGAPGPRGRDGEPGTPGNP-GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 198

Query: 83  LGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGP-SSEGPEEEDGE 137
           +  P GP  P GP  PA AP     Q     +  E  + G  GP    GP  + G+
Sbjct: 199 MQGPMGPMGPRGPPGPAGAPGPQGFQG-NPGEPGEPGVSGPMGPRGPPGPPGKPGD 253



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 37/126 (29%), Positives = 45/126 (35%), Gaps = 12/126 (9%)

Query: 29  RGAAASPEPARAPPEPAPPAEATGAPAPSRP---CAPEPAASPAGPE-EPGEPAGLGELG 84
           +G A     A AP    P    +GAP P  P     P+ A    GP    G P   G +G
Sbjct: 851 QGEAGQKGDAGAPGPQGP----SGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVG 906

Query: 85  EPAGPGEPEGPGDPAAA----PAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFS 140
            P   G P  PG P  +    P  A   +    +  E  L G  GP  E  E  D     
Sbjct: 907 PPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSG 966

Query: 141 FKYSPG 146
            +  PG
Sbjct: 967 AEGPPG 972



 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 32/105 (30%), Positives = 37/105 (35%), Gaps = 6/105 (5%)

Query: 39   RAPPEPAPPAEATG-APAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD 97
            R PP P  P   TG A  P R  +P     P      G     GE G    PG P  PG 
Sbjct: 1016 RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1075

Query: 98   PA-AAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137
            P  A P   +    EA  +      G  G       +GP  + GE
Sbjct: 1076 PGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGE 1120



 Score = 40.4 bits (93), Expect = 7e-04
 Identities = 32/103 (31%), Positives = 39/103 (37%), Gaps = 11/103 (10%)

Query: 38  ARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD 97
           A  PP PA PA   G        AP P+     P  PG P   G+ G+   PGE   PG 
Sbjct: 640 AAGPPGPAGPAGERGEQG-----APGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPG- 693

Query: 98  PAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDG 136
               P        E      Q L G +G    P ++GP+   G
Sbjct: 694 -LVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG 735



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 42/126 (33%), Positives = 49/126 (38%), Gaps = 19/126 (15%)

Query: 29  RGAA--ASPEPARAP-----PEPAPPAEA----TGAPAPSRPCAPEPAASPAGPEEPGEP 77
           RGAA  A P+  R       PE AP  +     TG   P  P          GP  P   
Sbjct: 755 RGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGS 814

Query: 78  AGL----GELGE--PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPS-SEG 130
           AG     GE GE  P GP    GP      P    EQ  EA Q+ +    G +GPS + G
Sbjct: 815 AGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQG-EAGQKGDAGAPGPQGPSGAPG 873

Query: 131 PEEEDG 136
           P+   G
Sbjct: 874 PQGPTG 879



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 33/124 (26%), Positives = 40/124 (32%), Gaps = 17/124 (13%)

Query: 30   GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89
            G A  P    +P    PP     A             +P  P  PG P   G  G+    
Sbjct: 1029 GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1088

Query: 90   GE-----PEGPGDPAAA-----PAEAEEQAVEARQEEEQDLDGEKG-------PSSEGPE 132
            GE     P GP  PA A     P        EA +  E+ L G +G       P   GP 
Sbjct: 1089 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS 1148

Query: 133  EEDG 136
             + G
Sbjct: 1149 GDQG 1152



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 25/68 (36%), Positives = 27/68 (39%), Gaps = 11/68 (16%)

Query: 33   ASPEPARAPPEPAPPAE---ATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGEPAG 88
            A P   R PP P  P+    A G P P  P  P   +   GP   PG P        P G
Sbjct: 1157 AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG-------PPG 1209

Query: 89   PGEPEGPG 96
            P  P GPG
Sbjct: 1210 PPGPPGPG 1217



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 43/144 (29%), Positives = 53/144 (36%), Gaps = 50/144 (34%)

Query: 29  RGAAASPEPARAPPEPAP-----PAEATGAPAPSR---------------------PCAP 62
           +G+A +P  A AP  P P     P  ATG   P                       P  P
Sbjct: 419 KGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP 478

Query: 63  EPAASPAGPEEP----GEPAGLGELG---EPAGPGEPEGPG-DPAAAPAEAEEQAVEARQ 114
           + A  PAG E      GEP G+G +G   E   PG    PG D  A P  A         
Sbjct: 479 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGA--------- 529

Query: 115 EEEQDLDGEKGPSS-EGPEEEDGE 137
                  GE+GPS   GP+  +G+
Sbjct: 530 ------PGERGPSGLAGPKGANGD 547



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 30/101 (29%), Positives = 37/101 (36%), Gaps = 19/101 (18%)

Query: 41   PPEPAPPAEATGAPAPSRPCAPEPAASPAG-------PEEPGEPAGLGELGE--PAGPGE 91
            PP P+    A+G   PS P  P     P+G       P   G P   G  GE  PAGP  
Sbjct: 1144 PPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPG 1203

Query: 92   PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPE 132
              GP  P   P    + +  A            GP  +GP+
Sbjct: 1204 NPGPPGPPGPPGPGIDMSAFA----------GLGPREKGPD 1234



 Score = 37.0 bits (84), Expect = 0.008
 Identities = 41/122 (33%), Positives = 46/122 (37%), Gaps = 23/122 (18%)

Query: 35  PEPARAPPEPAPPAEATGAPAPS----RPCAP-EPAAS-PAGPE-EPGEPAGLGELGEPA 87
           P   R PP PA      GAP P      P  P EP  S P GP   PG P   G+ GE  
Sbjct: 205 PMGPRGPPGPA------GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 258

Query: 88  GPGE-----PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGEG 138
            PG+     P GP      P       V+  +     LDG KG    P  +G     GE 
Sbjct: 259 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHR-GYPGLDGAKGEAGAPGVKGESGSPGEN 317

Query: 139 FS 140
            S
Sbjct: 318 GS 319



 Score = 37.0 bits (84), Expect = 0.008
 Identities = 22/70 (31%), Positives = 24/70 (34%), Gaps = 13/70 (18%)

Query: 42   PEPAPPAEATGAPAPSRPCAPEPAASPAGPE-------------EPGEPAGLGELGEPAG 88
            P P  P+   GA  P+ P  P     P GP               PG     GE G    
Sbjct: 1142 PGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP 1201

Query: 89   PGEPEGPGDP 98
            PG P  PG P
Sbjct: 1202 PGNPGPPGPP 1211



 Score = 35.8 bits (81), Expect = 0.018
 Identities = 21/69 (30%), Positives = 24/69 (34%), Gaps = 1/69 (1%)

Query: 31  AAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGEPAGP 89
           A+  P P     EP    +  G   P  P  P     P G   + GE    G  G    P
Sbjct: 96  ASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155

Query: 90  GEPEGPGDP 98
           G P  PG P
Sbjct: 156 GTPGNPGPP 164



 Score = 35.8 bits (81), Expect = 0.018
 Identities = 37/134 (27%), Positives = 46/134 (34%), Gaps = 39/134 (29%)

Query: 28  RRGAAASPEPARAPPEPAP-----------------PAEATGAPAPSRPCAPEPAASPAG 70
           ++G A +P P      P P                 P  ATG P  +    P  +    G
Sbjct: 856 QKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPG 915

Query: 71  PEEPGEPAG-------LGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGE 123
           P  P  P+G        G+ G P   GEP G   PA  P E  E              G+
Sbjct: 916 PPGPPGPSGKDGPKGARGDSGPPGRAGEP-GLQGPAGPPGEKGE-------------PGD 961

Query: 124 KGPS-SEGPEEEDG 136
            GPS +EGP    G
Sbjct: 962 DGPSGAEGPPGPQG 975



 Score = 35.4 bits (80), Expect = 0.024
 Identities = 35/112 (31%), Positives = 40/112 (35%), Gaps = 14/112 (12%)

Query: 30  GAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87
           G    P P  A  EP    E    GAP        +     AGP  P  PAG  E GE  
Sbjct: 600 GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG--ERGEQG 657

Query: 88  GPGEP--EGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDG 136
            PG    +G   P   P E  +         +Q + GE G P   GP  E G
Sbjct: 658 APGPSGFQGLPGPPGPPGEGGKPG-------DQGVPGEAGAPGLVGPRGERG 702



 Score = 34.7 bits (78), Expect = 0.041
 Identities = 34/143 (23%), Positives = 45/143 (31%), Gaps = 28/143 (19%)

Query: 29  RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE--- 85
           RG   +P P+     P PP        P     P  A +P      GE    GE G    
Sbjct: 653 RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA 712

Query: 86  -----------------------PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDG 122
                                  PAGP   +GP      P E     +   + +  D+ G
Sbjct: 713 QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV-G 771

Query: 123 EKGPSSEGPEEEDGEGFSFKYSP 145
           EKGP    P ++ G G +    P
Sbjct: 772 EKGPEG-APGKDGGRGLTGPIGP 793



 Score = 34.3 bits (77), Expect = 0.053
 Identities = 34/114 (29%), Positives = 38/114 (33%), Gaps = 21/114 (18%)

Query: 45  APPAEATGAPAPSRPCAPEPA-ASPAGPEEPGEPAGLGELGEPA------------GPGE 91
           A P  A G   PS    P+ A   P  P EPG P   G  G P              PGE
Sbjct: 524 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE 583

Query: 92  PEGPGDPAAAPAEAEEQAV----EARQEEEQDLDGEKG----PSSEGPEEEDGE 137
              PG P    A  +   +          E    GEKG    P   G   +DGE
Sbjct: 584 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 637



 Score = 33.9 bits (76), Expect = 0.069
 Identities = 37/122 (30%), Positives = 41/122 (33%), Gaps = 17/122 (13%)

Query: 30  GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPE-PAASPAGPEEPGEPAGLGELGE--- 85
           G A +P P      P  P E  G   P  P  P  P   P    E G+P   GE G    
Sbjct: 213 GPAGAPGPQGFQGNPGEPGEP-GVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGP 271

Query: 86  ------PAGPGEPEGPGD---PAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEED 135
                 P  PG P   G    P    A+ E  A   + E      GE G P   GP    
Sbjct: 272 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS--PGENGSPGPMGPRGLP 329

Query: 136 GE 137
           GE
Sbjct: 330 GE 331



 Score = 33.9 bits (76), Expect = 0.069
 Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 1/48 (2%)

Query: 52   GAPAPSRPCAPEPAASPAGPEEP-GEPAGLGELGEPAGPGEPEGPGDP 98
            G P P  P   + A+ PAGP  P G P  +G  G+    G P   G P
Sbjct: 1140 GLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP 1187



 Score = 33.1 bits (74), Expect = 0.12
 Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 19/83 (22%)

Query: 59  PCAPEPAASPAGPEEP----GEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQ 114
           P  P   A+ +G   P    GEP  + ++  P GP  P+GP         A EQ     +
Sbjct: 87  PICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGP---------AGEQGPRGDR 137

Query: 115 EEEQDLDGEKGPSSEGPEEEDGE 137
            ++    GEKG  + GP   DGE
Sbjct: 138 GDK----GEKG--APGPRGRDGE 154



 Score = 32.7 bits (73), Expect = 0.15
 Identities = 36/118 (30%), Positives = 45/118 (38%), Gaps = 14/118 (11%)

Query: 30   GAAASPEPARAPPEPAPPAEATGAPAPSRPCAP-----EPAAS-PAGPEEPGEPAGL--- 80
            G +    P  A  +  PP  A G P    P  P     EP    P+G E P  P GL   
Sbjct: 921  GPSGKDGPKGARGDSGPPGRA-GEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 979

Query: 81   -GELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDG 136
             G +G P   GE   PG P  +    ++ A  A    ++   G  GP    GP  E G
Sbjct: 980  RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA--SGDRGPPGPVGPPGLTGPAGEPG 1035



 Score = 32.3 bits (72), Expect = 0.20
 Identities = 34/122 (27%), Positives = 40/122 (32%), Gaps = 14/122 (11%)

Query: 29  RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG 88
           +G    P    A  E   P     + +P    +P P      P E G     G  G    
Sbjct: 287 KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN 346

Query: 89  PGEPE------------GPGDPAAAPAEAEEQAVEAR-QEEEQDLDGEKG-PSSEGPEEE 134
            G+P             GPG P A  A+ E     AR  E  Q   GE G P S GP   
Sbjct: 347 DGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA 406

Query: 135 DG 136
            G
Sbjct: 407 SG 408



 Score = 32.0 bits (71), Expect = 0.26
 Identities = 39/135 (28%), Positives = 46/135 (34%), Gaps = 29/135 (21%)

Query: 29  RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASP-----------------AGP 71
           +G    P PA     P P  E     A   P    P   P                 AGP
Sbjct: 467 QGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGP 526

Query: 72  E-EPGE--PAGL-GELGEPAGPGEPEGPGDPAA-----APAEAEEQAVEARQEEEQDLDG 122
           +  PGE  P+GL G  G    PG P  PG P A      P +A  Q  +         DG
Sbjct: 527 KGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQG-KVGPSGAPGEDG 585

Query: 123 EKGPSSEGPEEEDGE 137
             GP   GP+   G+
Sbjct: 586 RPGP--PGPQGARGQ 598



 Score = 32.0 bits (71), Expect = 0.26
 Identities = 43/155 (27%), Positives = 48/155 (30%), Gaps = 47/155 (30%)

Query: 30  GAAASPEPARA--------PPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGL 80
           G    P PA A        PP PA  A A GAP       P   A  AGP    G+P   
Sbjct: 789 GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 848

Query: 81  GELGE--------------PAGPGEPEGP-------------------GDPAAA----PA 103
           GE GE              P+G   P+GP                   G P AA    P 
Sbjct: 849 GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 908

Query: 104 EAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGE 137
            +               DG KG   + GP    GE
Sbjct: 909 GSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 943



 Score = 31.6 bits (70), Expect = 0.34
 Identities = 36/122 (29%), Positives = 41/122 (33%), Gaps = 9/122 (7%)

Query: 30  GAAASPEPA--RAPPEPAPPAEATGAPA-PSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86
           G A  P  A  R PP P     A G P  P  P        P      GE    G  GE 
Sbjct: 255 GEAGKPGKAGERGPPGPQG---ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 311

Query: 87  AGPGEPEGPG--DPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYS 144
             PGE   PG   P   P E   +   A     +  DG+ GP+          G  F  +
Sbjct: 312 GSPGENGSPGPMGPRGLPGE-RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGA 370

Query: 145 PG 146
           PG
Sbjct: 371 PG 372



 Score = 31.2 bits (69), Expect = 0.45
 Identities = 30/109 (27%), Positives = 36/109 (33%), Gaps = 5/109 (4%)

Query: 33  ASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGE--PAGP 89
           A P  A+ PP         GA   + P          GPE  PG+  G G  G   P GP
Sbjct: 737 AGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGP 796

Query: 90  GEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDGE 137
               G       P  A          E  +  G  GP+   GP   DG+
Sbjct: 797 AGANGEKGEVGPPGPAGSAGARGAPGERGE-TGPPGPAGFAGPPGADGQ 844



 Score = 30.0 bits (66), Expect = 1.0
 Identities = 34/121 (28%), Positives = 39/121 (32%), Gaps = 13/121 (10%)

Query: 29  RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEE-PGEPAGLGELGEPA 87
           RG    P  A  P     P+ A G      P  P+ A    G    PG     GE G+  
Sbjct: 560 RGLTGRPGDA-GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 618

Query: 88  GPGEPEGPG-------DPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDG 136
             G P  PG       D     A     A  A +  EQ   G  G    P   GP  E G
Sbjct: 619 EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGG 678

Query: 137 E 137
           +
Sbjct: 679 K 679



 Score = 29.6 bits (65), Expect = 1.3
 Identities = 21/59 (35%), Positives = 22/59 (37%), Gaps = 8/59 (13%)

Query: 41   PPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGL-GELGEPAGPGEPEGPGDP 98
            P  P P  E     AP        A+   GP  P  P GL G  GEP   G P   G P
Sbjct: 995  PGLPGPSGEPGKQGAPG-------ASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 1046



 Score = 29.6 bits (65), Expect = 1.3
 Identities = 20/72 (27%), Positives = 21/72 (29%), Gaps = 25/72 (34%)

Query: 52   GAPAPSRPCAPEPAASPAGPEEPGEPAG-------------------------LGELGEP 86
            G P PS        A P+GP  P  P G                          G  G P
Sbjct: 1143 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPP 1202

Query: 87   AGPGEPEGPGDP 98
              PG P  PG P
Sbjct: 1203 GNPGPPGPPGPP 1214



 Score = 29.3 bits (64), Expect = 1.7
 Identities = 26/89 (29%), Positives = 32/89 (35%), Gaps = 11/89 (12%)

Query: 52   GAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVE 111
            G P PS     + A   +G   P  P G   L  PA  GEP   G P A      + A  
Sbjct: 996  GLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA--GEPGREGSPGADGPPGRDGAAG 1053

Query: 112  ARQEEEQDLDGEKG----PSSEGPEEEDG 136
             + +      GE G    P + GP    G
Sbjct: 1054 VKGDR-----GETGAVGAPGAPGPPGSPG 1077



 Score = 29.3 bits (64), Expect = 1.7
 Identities = 29/97 (29%), Positives = 33/97 (34%), Gaps = 11/97 (11%)

Query: 42   PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAA 101
            P P+      GAP  S    P     P GP  PG     GE G    PG    PG   AA
Sbjct: 998  PGPSGEPGKQGAPGASGDRGPP---GPVGP--PGLTGPAGEPGREGSPGADGPPGRDGAA 1052

Query: 102  PAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDGE 137
              + +     A         G  G P S GP    G+
Sbjct: 1053 GVKGDRGETGA-----VGAPGAPGPPGSPGPAGPTGK 1084


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 51.2 bits (121), Expect = 4e-07
 Identities = 42/128 (32%), Positives = 51/128 (39%), Gaps = 22/128 (17%)

Query: 30  GAAASPEPARAPPEPAPP--------------AEATGAPAPSRPCAPEPAASPAGPE-EP 74
           G   SP PA A   P                 A A G P P  P  P+ A  P GP+ + 
Sbjct: 327 GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT 386

Query: 75  GEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL-----DGEKG-PSS 128
           GEP   G  GE    GEP GP  P  AP  A E+     + E   +      GE+G P +
Sbjct: 387 GEPGIAGFKGEQGPKGEP-GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGN 445

Query: 129 EGPEEEDG 136
            G   +DG
Sbjct: 446 RGFPGQDG 453



 Score = 44.7 bits (104), Expect = 4e-05
 Identities = 38/113 (33%), Positives = 46/113 (40%), Gaps = 11/113 (9%)

Query: 30  GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGEPAG 88
           GAA    P  +   P PP    G P PS    P+ A   +GP    GEP   G  G P  
Sbjct: 831 GAAGRVGPPGSNGNPGPP----GPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGE 886

Query: 89  PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137
            GEP G   P+ A      Q + A Q     L G++G    P   GP  E G+
Sbjct: 887 KGEP-GDDGPSGAEGPPGPQGL-AGQRGIVGLPGQRGERGFPGLPGPSGEPGK 937



 Score = 43.9 bits (102), Expect = 7e-05
 Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 13/104 (12%)

Query: 44  PAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD--PAAA 101
           P  P    G P P+   AP P      P EPGEP   G +G    PG P  PGD   A  
Sbjct: 133 PMGPMGPRGPPGPAG--APGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGK 190

Query: 102 PAEAEEQAVEARQEEE-----QDLDGEKG----PSSEGPEEEDG 136
           P +A E+     Q          L G KG    P  +G + E G
Sbjct: 191 PGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAG 234



 Score = 42.7 bits (99), Expect = 1e-04
 Identities = 40/149 (26%), Positives = 50/149 (33%), Gaps = 42/149 (28%)

Query: 29  RGAAASPEPARAPPEPAPPAEATGAPA-------------------------PSRPCAPE 63
           RG    P PA  PP P  PA   G P                          P  P +P 
Sbjct: 275 RGNDGQPGPA-GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPG 333

Query: 64  PAASPAGPEEPGEPAGLGELGEPA-----------GPGEPEGPGDPAAAPAEAEEQAVEA 112
           PA +   P   G P   G  G P            GP  P+G   P     +  E  + A
Sbjct: 334 PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI-A 392

Query: 113 RQEEEQDLDGEKGPS----SEGPEEEDGE 137
             + EQ   GE GP+    + GP  E+G+
Sbjct: 393 GFKGEQGPKGEPGPAGPQGAPGPAGEEGK 421



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 35/116 (30%), Positives = 43/116 (37%), Gaps = 9/116 (7%)

Query: 29  RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPE------PAASPAGPEEPGEPAGLGE 82
           +G   +P P     EP  P    G P P  P  P        A    G +E    A LG 
Sbjct: 71  KGEKGAPGPRGRDGEPGTPGNP-GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 129

Query: 83  LGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGP-SSEGPEEEDGE 137
           +  P GP  P GP  PA AP     Q     +  E  + G  GP    GP  + G+
Sbjct: 130 MQGPMGPMGPRGPPGPAGAPGPQGFQG-NPGEPGEPGVSGPMGPRGPPGPPGKPGD 184



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 30/92 (32%), Positives = 34/92 (36%), Gaps = 5/92 (5%)

Query: 12 PALATALALLLAWLLVRRGA-AASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAG 70
          P     L LL+A +L  +G     P P     EP    +  G   P  P  P     P G
Sbjct: 7  PQTLVLLTLLVAAVLRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRG 66

Query: 71 PE----EPGEPAGLGELGEPAGPGEPEGPGDP 98
                E G P   G  GEP  PG P  PG P
Sbjct: 67 DRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPP 98



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 37/126 (29%), Positives = 45/126 (35%), Gaps = 12/126 (9%)

Query: 29  RGAAASPEPARAPPEPAPPAEATGAPAPSRP---CAPEPAASPAGPE-EPGEPAGLGELG 84
           +G A     A AP    P    +GAP P  P     P+ A    GP    G P   G +G
Sbjct: 782 QGEAGQKGDAGAPGPQGP----SGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVG 837

Query: 85  EPAGPGEPEGPGDPAAA----PAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFS 140
            P   G P  PG P  +    P  A   +    +  E  L G  GP  E  E  D     
Sbjct: 838 PPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSG 897

Query: 141 FKYSPG 146
            +  PG
Sbjct: 898 AEGPPG 903



 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 32/105 (30%), Positives = 37/105 (35%), Gaps = 6/105 (5%)

Query: 39   RAPPEPAPPAEATG-APAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD 97
            R PP P  P   TG A  P R  +P     P      G     GE G    PG P  PG 
Sbjct: 947  RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1006

Query: 98   PA-AAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137
            P  A P   +    EA  +      G  G       +GP  + GE
Sbjct: 1007 PGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGE 1051



 Score = 40.4 bits (93), Expect = 7e-04
 Identities = 32/103 (31%), Positives = 39/103 (37%), Gaps = 11/103 (10%)

Query: 38  ARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD 97
           A  PP PA PA   G        AP P+     P  PG P   G+ G+   PGE   PG 
Sbjct: 571 AAGPPGPAGPAGERGEQG-----APGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPG- 624

Query: 98  PAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDG 136
               P        E      Q L G +G    P ++GP+   G
Sbjct: 625 -LVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG 666



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 42/126 (33%), Positives = 49/126 (38%), Gaps = 19/126 (15%)

Query: 29  RGAA--ASPEPARAP-----PEPAPPAEA----TGAPAPSRPCAPEPAASPAGPEEPGEP 77
           RGAA  A P+  R       PE AP  +     TG   P  P          GP  P   
Sbjct: 686 RGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGS 745

Query: 78  AGL----GELGE--PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPS-SEG 130
           AG     GE GE  P GP    GP      P    EQ  EA Q+ +    G +GPS + G
Sbjct: 746 AGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQG-EAGQKGDAGAPGPQGPSGAPG 804

Query: 131 PEEEDG 136
           P+   G
Sbjct: 805 PQGPTG 810



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 33/124 (26%), Positives = 40/124 (32%), Gaps = 17/124 (13%)

Query: 30   GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89
            G A  P    +P    PP     A             +P  P  PG P   G  G+    
Sbjct: 960  GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1019

Query: 90   GE-----PEGPGDPAAA-----PAEAEEQAVEARQEEEQDLDGEKG-------PSSEGPE 132
            GE     P GP  PA A     P        EA +  E+ L G +G       P   GP 
Sbjct: 1020 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS 1079

Query: 133  EEDG 136
             + G
Sbjct: 1080 GDQG 1083



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 25/68 (36%), Positives = 27/68 (39%), Gaps = 11/68 (16%)

Query: 33   ASPEPARAPPEPAPPA---EATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGEPAG 88
            A P   R PP P  P+    A G P P  P  P   +   GP   PG P        P G
Sbjct: 1088 AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG-------PPG 1140

Query: 89   PGEPEGPG 96
            P  P GPG
Sbjct: 1141 PPGPPGPG 1148



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 43/144 (29%), Positives = 53/144 (36%), Gaps = 50/144 (34%)

Query: 29  RGAAASPEPARAPPEPAP-----PAEATGAPAPSR---------------------PCAP 62
           +G+A +P  A AP  P P     P  ATG   P                       P  P
Sbjct: 350 KGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP 409

Query: 63  EPAASPAGPEEP----GEPAGLGELG---EPAGPGEPEGPG-DPAAAPAEAEEQAVEARQ 114
           + A  PAG E      GEP G+G +G   E   PG    PG D  A P  A         
Sbjct: 410 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGA--------- 460

Query: 115 EEEQDLDGEKGPSS-EGPEEEDGE 137
                  GE+GPS   GP+  +G+
Sbjct: 461 ------PGERGPSGLAGPKGANGD 478



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 30/101 (29%), Positives = 37/101 (36%), Gaps = 19/101 (18%)

Query: 41   PPEPAPPAEATGAPAPSRPCAPEPAASPAG-------PEEPGEPAGLGELGE--PAGPGE 91
            PP P+    A+G   PS P  P     P+G       P   G P   G  GE  PAGP  
Sbjct: 1075 PPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPG 1134

Query: 92   PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPE 132
              GP  P   P    + +  A            GP  +GP+
Sbjct: 1135 NPGPPGPPGPPGPGIDMSAFA----------GLGPREKGPD 1165



 Score = 37.0 bits (84), Expect = 0.008
 Identities = 41/122 (33%), Positives = 46/122 (37%), Gaps = 23/122 (18%)

Query: 35  PEPARAPPEPAPPAEATGAPAPS----RPCAP-EPAAS-PAGPE-EPGEPAGLGELGEPA 87
           P   R PP PA      GAP P      P  P EP  S P GP   PG P   G+ GE  
Sbjct: 136 PMGPRGPPGPA------GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 189

Query: 88  GPGE-----PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGEG 138
            PG+     P GP      P       V+  +     LDG KG    P  +G     GE 
Sbjct: 190 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHR-GYPGLDGAKGEAGAPGVKGESGSPGEN 248

Query: 139 FS 140
            S
Sbjct: 249 GS 250



 Score = 37.0 bits (84), Expect = 0.008
 Identities = 22/70 (31%), Positives = 24/70 (34%), Gaps = 13/70 (18%)

Query: 42   PEPAPPAEATGAPAPSRPCAPEPAASPAGPE-------------EPGEPAGLGELGEPAG 88
            P P  P+   GA  P+ P  P     P GP               PG     GE G    
Sbjct: 1073 PGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP 1132

Query: 89   PGEPEGPGDP 98
            PG P  PG P
Sbjct: 1133 PGNPGPPGPP 1142



 Score = 35.8 bits (81), Expect = 0.018
 Identities = 37/134 (27%), Positives = 46/134 (34%), Gaps = 39/134 (29%)

Query: 28  RRGAAASPEPARAPPEPAP-----------------PAEATGAPAPSRPCAPEPAASPAG 70
           ++G A +P P      P P                 P  ATG P  +    P  +    G
Sbjct: 787 QKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPG 846

Query: 71  PEEPGEPAG-------LGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGE 123
           P  P  P+G        G+ G P   GEP G   PA  P E  E              G+
Sbjct: 847 PPGPPGPSGKDGPKGARGDSGPPGRAGEP-GLQGPAGPPGEKGE-------------PGD 892

Query: 124 KGPS-SEGPEEEDG 136
            GPS +EGP    G
Sbjct: 893 DGPSGAEGPPGPQG 906



 Score = 35.4 bits (80), Expect = 0.024
 Identities = 35/112 (31%), Positives = 40/112 (35%), Gaps = 14/112 (12%)

Query: 30  GAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87
           G    P P  A  EP    E    GAP        +     AGP  P  PAG  E GE  
Sbjct: 531 GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG--ERGEQG 588

Query: 88  GPGEP--EGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDG 136
            PG    +G   P   P E  +         +Q + GE G P   GP  E G
Sbjct: 589 APGPSGFQGLPGPPGPPGEGGKPG-------DQGVPGEAGAPGLVGPRGERG 633



 Score = 34.7 bits (78), Expect = 0.041
 Identities = 34/143 (23%), Positives = 45/143 (31%), Gaps = 28/143 (19%)

Query: 29  RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE--- 85
           RG   +P P+     P PP        P     P  A +P      GE    GE G    
Sbjct: 584 RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA 643

Query: 86  -----------------------PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDG 122
                                  PAGP   +GP      P E     +   + +  D+ G
Sbjct: 644 QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV-G 702

Query: 123 EKGPSSEGPEEEDGEGFSFKYSP 145
           EKGP    P ++ G G +    P
Sbjct: 703 EKGPEG-APGKDGGRGLTGPIGP 724



 Score = 34.3 bits (77), Expect = 0.053
 Identities = 34/114 (29%), Positives = 38/114 (33%), Gaps = 21/114 (18%)

Query: 45  APPAEATGAPAPSRPCAPEPA-ASPAGPEEPGEPAGLGELGEPA------------GPGE 91
           A P  A G   PS    P+ A   P  P EPG P   G  G P              PGE
Sbjct: 455 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE 514

Query: 92  PEGPGDPAAAPAEAEEQAV----EARQEEEQDLDGEKG----PSSEGPEEEDGE 137
              PG P    A  +   +          E    GEKG    P   G   +DGE
Sbjct: 515 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 568



 Score = 33.9 bits (76), Expect = 0.069
 Identities = 37/122 (30%), Positives = 41/122 (33%), Gaps = 17/122 (13%)

Query: 30  GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPE-PAASPAGPEEPGEPAGLGELGE--- 85
           G A +P P      P  P E  G   P  P  P  P   P    E G+P   GE G    
Sbjct: 144 GPAGAPGPQGFQGNPGEPGEP-GVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGP 202

Query: 86  ------PAGPGEPEGPGD---PAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEED 135
                 P  PG P   G    P    A+ E  A   + E      GE G P   GP    
Sbjct: 203 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS--PGENGSPGPMGPRGLP 260

Query: 136 GE 137
           GE
Sbjct: 261 GE 262



 Score = 33.9 bits (76), Expect = 0.069
 Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 1/48 (2%)

Query: 52   GAPAPSRPCAPEPAASPAGPEEP-GEPAGLGELGEPAGPGEPEGPGDP 98
            G P P  P   + A+ PAGP  P G P  +G  G+    G P   G P
Sbjct: 1071 GLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP 1118



 Score = 33.1 bits (74), Expect = 0.12
 Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 15/78 (19%)

Query: 60  CAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQD 119
           C  +    P    + GEP  + ++  P GP  P+GP         A EQ     + ++  
Sbjct: 23  CQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGP---------AGEQGPRGDRGDK-- 71

Query: 120 LDGEKGPSSEGPEEEDGE 137
             GEKG  + GP   DGE
Sbjct: 72  --GEKG--APGPRGRDGE 85



 Score = 32.7 bits (73), Expect = 0.15
 Identities = 36/118 (30%), Positives = 45/118 (38%), Gaps = 14/118 (11%)

Query: 30  GAAASPEPARAPPEPAPPAEATGAPAPSRPCAP-----EPAAS-PAGPEEPGEPAGL--- 80
           G +    P  A  +  PP  A G P    P  P     EP    P+G E P  P GL   
Sbjct: 852 GPSGKDGPKGARGDSGPPGRA-GEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 910

Query: 81  -GELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDG 136
            G +G P   GE   PG P  +    ++ A  A    ++   G  GP    GP  E G
Sbjct: 911 RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA--SGDRGPPGPVGPPGLTGPAGEPG 966



 Score = 32.3 bits (72), Expect = 0.20
 Identities = 34/122 (27%), Positives = 40/122 (32%), Gaps = 14/122 (11%)

Query: 29  RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG 88
           +G    P    A  E   P     + +P    +P P      P E G     G  G    
Sbjct: 218 KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN 277

Query: 89  PGEPE------------GPGDPAAAPAEAEEQAVEAR-QEEEQDLDGEKG-PSSEGPEEE 134
            G+P             GPG P A  A+ E     AR  E  Q   GE G P S GP   
Sbjct: 278 DGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA 337

Query: 135 DG 136
            G
Sbjct: 338 SG 339



 Score = 32.0 bits (71), Expect = 0.26
 Identities = 39/135 (28%), Positives = 46/135 (34%), Gaps = 29/135 (21%)

Query: 29  RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASP-----------------AGP 71
           +G    P PA     P P  E     A   P    P   P                 AGP
Sbjct: 398 QGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGP 457

Query: 72  E-EPGE--PAGL-GELGEPAGPGEPEGPGDPAA-----APAEAEEQAVEARQEEEQDLDG 122
           +  PGE  P+GL G  G    PG P  PG P A      P +A  Q  +         DG
Sbjct: 458 KGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQG-KVGPSGAPGEDG 516

Query: 123 EKGPSSEGPEEEDGE 137
             GP   GP+   G+
Sbjct: 517 RPGP--PGPQGARGQ 529



 Score = 32.0 bits (71), Expect = 0.26
 Identities = 43/155 (27%), Positives = 48/155 (30%), Gaps = 47/155 (30%)

Query: 30  GAAASPEPARA--------PPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGL 80
           G    P PA A        PP PA  A A GAP       P   A  AGP    G+P   
Sbjct: 720 GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 779

Query: 81  GELGE--------------PAGPGEPEGP-------------------GDPAAA----PA 103
           GE GE              P+G   P+GP                   G P AA    P 
Sbjct: 780 GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 839

Query: 104 EAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGE 137
            +               DG KG   + GP    GE
Sbjct: 840 GSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 874



 Score = 31.6 bits (70), Expect = 0.34
 Identities = 36/122 (29%), Positives = 41/122 (33%), Gaps = 9/122 (7%)

Query: 30  GAAASPEPA--RAPPEPAPPAEATGAPA-PSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86
           G A  P  A  R PP P     A G P  P  P        P      GE    G  GE 
Sbjct: 186 GEAGKPGKAGERGPPGPQG---ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 242

Query: 87  AGPGEPEGPG--DPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYS 144
             PGE   PG   P   P E   +   A     +  DG+ GP+          G  F  +
Sbjct: 243 GSPGENGSPGPMGPRGLPGE-RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGA 301

Query: 145 PG 146
           PG
Sbjct: 302 PG 303



 Score = 31.2 bits (69), Expect = 0.45
 Identities = 30/109 (27%), Positives = 36/109 (33%), Gaps = 5/109 (4%)

Query: 33  ASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGE--PAGP 89
           A P  A+ PP         GA   + P          GPE  PG+  G G  G   P GP
Sbjct: 668 AGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGP 727

Query: 90  GEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDGE 137
               G       P  A          E  +  G  GP+   GP   DG+
Sbjct: 728 AGANGEKGEVGPPGPAGSAGARGAPGERGE-TGPPGPAGFAGPPGADGQ 775



 Score = 30.0 bits (66), Expect = 1.0
 Identities = 34/121 (28%), Positives = 39/121 (32%), Gaps = 13/121 (10%)

Query: 29  RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEE-PGEPAGLGELGEPA 87
           RG    P  A  P     P+ A G      P  P+ A    G    PG     GE G+  
Sbjct: 491 RGLTGRPGDA-GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 549

Query: 88  GPGEPEGPG-------DPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDG 136
             G P  PG       D     A     A  A +  EQ   G  G    P   GP  E G
Sbjct: 550 EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGG 609

Query: 137 E 137
           +
Sbjct: 610 K 610



 Score = 29.6 bits (65), Expect = 1.3
 Identities = 21/59 (35%), Positives = 22/59 (37%), Gaps = 8/59 (13%)

Query: 41  PPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGL-GELGEPAGPGEPEGPGDP 98
           P  P P  E     AP        A+   GP  P  P GL G  GEP   G P   G P
Sbjct: 926 PGLPGPSGEPGKQGAPG-------ASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 977



 Score = 29.6 bits (65), Expect = 1.3
 Identities = 20/72 (27%), Positives = 21/72 (29%), Gaps = 25/72 (34%)

Query: 52   GAPAPSRPCAPEPAASPAGPEEPGEPAG-------------------------LGELGEP 86
            G P PS        A P+GP  P  P G                          G  G P
Sbjct: 1074 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPP 1133

Query: 87   AGPGEPEGPGDP 98
              PG P  PG P
Sbjct: 1134 GNPGPPGPPGPP 1145



 Score = 29.3 bits (64), Expect = 1.7
 Identities = 26/89 (29%), Positives = 32/89 (35%), Gaps = 11/89 (12%)

Query: 52   GAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVE 111
            G P PS     + A   +G   P  P G   L  PA  GEP   G P A      + A  
Sbjct: 927  GLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA--GEPGREGSPGADGPPGRDGAAG 984

Query: 112  ARQEEEQDLDGEKG----PSSEGPEEEDG 136
             + +      GE G    P + GP    G
Sbjct: 985  VKGDR-----GETGAVGAPGAPGPPGSPG 1008



 Score = 29.3 bits (64), Expect = 1.7
 Identities = 29/97 (29%), Positives = 33/97 (34%), Gaps = 11/97 (11%)

Query: 42   PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAA 101
            P P+      GAP  S    P     P GP  PG     GE G    PG    PG   AA
Sbjct: 929  PGPSGEPGKQGAPGASGDRGPP---GPVGP--PGLTGPAGEPGREGSPGADGPPGRDGAA 983

Query: 102  PAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDGE 137
              + +     A         G  G P S GP    G+
Sbjct: 984  GVKGDRGETGA-----VGAPGAPGPPGSPGPAGPTGK 1015


>gi|24308115 interferon regulatory factor 2 binding protein 1 [Homo
           sapiens]
          Length = 584

 Score = 50.8 bits (120), Expect = 5e-07
 Identities = 41/109 (37%), Positives = 45/109 (41%), Gaps = 15/109 (13%)

Query: 35  PEPARAPPEPAP---PAEATGAP--APSRPCAPEPAASPAGPEEPGEPAGLGELGE---- 85
           P PA A P+  P   PA   G P  APSR  AP P    A PE  GE AG     E    
Sbjct: 344 PAPAEALPQQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQR 403

Query: 86  ----PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEG 130
               P GP   E PG P  +P  A +   EA     +D  G  GP   G
Sbjct: 404 HWVAPGGPYSAETPGVP--SPIAALKNVAEALGHSPKDPGGGGGPVRAG 450


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 50.4 bits (119), Expect = 7e-07
 Identities = 41/108 (37%), Positives = 51/108 (47%), Gaps = 15/108 (13%)

Query: 35  PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG 94
           PE   AP EP P +EATGAP P  P  P P+A P  P  P E     E  E      P  
Sbjct: 770 PEDIPAPTEPTPASEATGAPTPP-PAPPSPSAPP--PVVPKE-----EKEEETAAAPPVE 821

Query: 95  PGDPAAAPAEAEEQAVEARQEEEQ-----DLDGEKGPSSEGPEEEDGE 137
            G+    PA AEE AV+  + EE        + E+GP ++G + E  E
Sbjct: 822 EGEEQKPPA-AEELAVDTGKAEEPVKSECTEEAEEGP-AKGKDAEAAE 867



 Score = 36.6 bits (83), Expect = 0.011
 Identities = 44/175 (25%), Positives = 58/175 (33%), Gaps = 41/175 (23%)

Query: 28  RRGAAASPEPARAPP-----------------EPAPPAEATGAPAPSRPCAPEP---AAS 67
           ++  AA+ E A  PP                 E    AEAT   +      P P   AA 
Sbjct: 684 KKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAK 743

Query: 68  PAGPEEPGEPAGLGELGEPAGPGEPE------------------GPGDPAAAPAEAEEQA 109
             G   P  PA LG  G P GP  P                    P  P A P+ +    
Sbjct: 744 DTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPP 803

Query: 110 VEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEE 164
           V  ++E+E++      P  EG E++           GK    +  K    EE EE
Sbjct: 804 VVPKEEKEEE-TAAAPPVEEGEEQKPPAAEELAVDTGK--AEEPVKSECTEEAEE 855



 Score = 31.6 bits (70), Expect = 0.34
 Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 9/75 (12%)

Query: 42   PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGP--GDPA 99
            P P PP E   A     P AP+P+A    P  PG P  LG L + A P  P  P   +P 
Sbjct: 1045 PFPVPPREVIKAS----PHAPDPSAFSYAP--PGHPLPLG-LHDTARPVLPRPPTISNPP 1097

Query: 100  AAPAEAEEQAVEARQ 114
               + A+  +V  RQ
Sbjct: 1098 PLISSAKHPSVLERQ 1112



 Score = 30.4 bits (67), Expect = 0.77
 Identities = 26/84 (30%), Positives = 33/84 (39%), Gaps = 2/84 (2%)

Query: 26   LVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPA-GPEEPG-EPAGLGEL 83
            L +R AA  P       EP     A   PAP  P  P+     +  P++PG  P G    
Sbjct: 949  LKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRS 1008

Query: 84   GEPAGPGEPEGPGDPAAAPAEAEE 107
              P    E E P    A  AEA++
Sbjct: 1009 PAPPADKEAEKPVFFPAFAAEAQK 1032



 Score = 26.9 bits (58), Expect = 8.5
 Identities = 16/41 (39%), Positives = 17/41 (41%), Gaps = 1/41 (2%)

Query: 47   PAEATGAPAPSRPCAPE-PAASPAGPEEPGEPAGLGELGEP 86
            P+ A   P P  P      A   A P  PG PAG G L  P
Sbjct: 2399 PSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGP 2439


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 50.4 bits (119), Expect = 7e-07
 Identities = 41/108 (37%), Positives = 51/108 (47%), Gaps = 15/108 (13%)

Query: 35  PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG 94
           PE   AP EP P +EATGAP P  P  P P+A P  P  P E     E  E      P  
Sbjct: 787 PEDIPAPTEPTPASEATGAPTPP-PAPPSPSAPP--PVVPKE-----EKEEETAAAPPVE 838

Query: 95  PGDPAAAPAEAEEQAVEARQEEEQ-----DLDGEKGPSSEGPEEEDGE 137
            G+    PA AEE AV+  + EE        + E+GP ++G + E  E
Sbjct: 839 EGEEQKPPA-AEELAVDTGKAEEPVKSECTEEAEEGP-AKGKDAEAAE 884



 Score = 37.0 bits (84), Expect = 0.008
 Identities = 37/145 (25%), Positives = 48/145 (33%), Gaps = 10/145 (6%)

Query: 27  VRRGAAASPEPARAPPE----PAPPAEA---TGAPAPSRPCAPEPAASPAGPEEPGEPAG 79
           V RG  + P       +    P+P  EA   TG   P  P        P GP  P  P  
Sbjct: 731 VPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTP-PPED 789

Query: 80  LGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGF 139
           +    EP    E  G   P  AP           +EE+++      P  EG E++     
Sbjct: 790 IPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAE 849

Query: 140 SFKYSPGKLRGNQYKKMMTKEELEE 164
                 GK    +  K    EE EE
Sbjct: 850 ELAVDTGK--AEEPVKSECTEEAEE 872



 Score = 34.3 bits (77), Expect = 0.053
 Identities = 33/92 (35%), Positives = 40/92 (43%), Gaps = 19/92 (20%)

Query: 26   LVRRGAAASP------EPAR---APPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPG- 75
            L +R AA  P      EP R   AP +PAPPA     P P +   PE  A    P++PG 
Sbjct: 966  LKQRAAAIPPIVTKVHEPPREDAAPTKPAPPA-----PPPPQNLQPESDA----PQQPGS 1016

Query: 76   EPAGLGELGEPAGPGEPEGPGDPAAAPAEAEE 107
             P G      P    E E P    A  AEA++
Sbjct: 1017 SPRGKSRSPAPPADKEAEKPVFFPAFAAEAQK 1048



 Score = 31.6 bits (70), Expect = 0.34
 Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 9/75 (12%)

Query: 42   PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGP--GDPA 99
            P P PP E   A     P AP+P+A    P  PG P  LG L + A P  P  P   +P 
Sbjct: 1061 PFPVPPREVIKAS----PHAPDPSAFSYAP--PGHPLPLG-LHDTARPVLPRPPTISNPP 1113

Query: 100  AAPAEAEEQAVEARQ 114
               + A+  +V  RQ
Sbjct: 1114 PLISSAKHPSVLERQ 1128



 Score = 26.9 bits (58), Expect = 8.5
 Identities = 16/41 (39%), Positives = 17/41 (41%), Gaps = 1/41 (2%)

Query: 47   PAEATGAPAPSRPCAPE-PAASPAGPEEPGEPAGLGELGEP 86
            P+ A   P P  P      A   A P  PG PAG G L  P
Sbjct: 2461 PSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGP 2501


>gi|153070260 myristoylated alanine-rich protein kinase C substrate
           [Homo sapiens]
          Length = 332

 Score = 50.4 bits (119), Expect = 7e-07
 Identities = 48/139 (34%), Positives = 59/139 (42%), Gaps = 19/139 (13%)

Query: 31  AAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPG 90
           AA   EPA A    A P+ A     P+   APE  ASP   E P E             G
Sbjct: 66  AADKEEPAAAGSGAASPSAAEKGE-PAAAAAPEAGASPVEKEAPAE-------------G 111

Query: 91  EPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKLRG 150
           E   PG P AA  EA   A      + +D      PS+E P+++  + FSFK S  KL G
Sbjct: 112 EAAEPGSPTAAEGEAASAASSTSSPKAED-GATPSPSNETPKKKK-KRFSFKKS-FKLSG 168

Query: 151 NQYKKMMTKEELEEEQRTE 169
             +KK   K+E  E    E
Sbjct: 169 FSFKK--NKKEAGEGGEAE 185



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 37/112 (33%), Positives = 44/112 (39%), Gaps = 12/112 (10%)

Query: 31  AAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGP--------EEPGEPAGLGE 82
           AA     A   P+ A P EA  A AP +P A +   +   P        EE G  A   E
Sbjct: 223 AAGEEGAAGGDPQEAKPQEA--AVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACE 280

Query: 83  LGEPAGPG-EPEGPGDPAAAP-AEAEEQAVEARQEEEQDLDGEKGPSSEGPE 132
               AGPG  PE    PA  P A A   A  A  +E Q     + P +E  E
Sbjct: 281 APSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332



 Score = 37.4 bits (85), Expect = 0.006
 Identities = 33/105 (31%), Positives = 40/105 (38%), Gaps = 6/105 (5%)

Query: 38  ARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD 97
           A AP       EA G  A +   A   AAS      PGE A  GE G   G  +   P +
Sbjct: 184 AEAPAAEGGKDEAAGGAAAA--AAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQE 241

Query: 98  PAAA----PAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEG 138
            A A    PA  E +A E   + E+    E G S+   E     G
Sbjct: 242 AAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAG 286



 Score = 30.4 bits (67), Expect = 0.77
 Identities = 20/47 (42%), Positives = 23/47 (48%), Gaps = 3/47 (6%)

Query: 30  GAAASPEPARAP-PEPAPPAEATGAPAPSRPCAPE--PAASPAGPEE 73
           G  A PE   AP  EPA  A ++   APS+   PE  P A PA   E
Sbjct: 286 GPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332



 Score = 28.5 bits (62), Expect = 2.9
 Identities = 24/78 (30%), Positives = 29/78 (37%), Gaps = 18/78 (23%)

Query: 30  GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89
           GA+A+   A +   P  P E   APA                EEP   A       P+  
Sbjct: 273 GASAAACEAPSAAGPGAPPEQEAAPA----------------EEPAAAAASSACAAPSQE 316

Query: 90  GEPEGPGDPAAAPAEAEE 107
            +PE    P A PAEA E
Sbjct: 317 AQPE--CSPEAPPAEAAE 332


>gi|32307177 forkhead box G1 [Homo sapiens]
          Length = 489

 Score = 50.4 bits (119), Expect = 7e-07
 Identities = 44/141 (31%), Positives = 58/141 (41%), Gaps = 19/141 (13%)

Query: 35  PEPARAPPEPAPPA----EATGAPAPSRPCAPEPAASPAGPEEPGEPA-------GLGEL 83
           P   + PP P PPA    +  GAPA      P+    P  P  P   A       GLG  
Sbjct: 68  PPQQQQPPPPPPPAPQPPQTRGAPAADDDKGPQQLLLPPPPPPPPAAALDGAKADGLGGK 127

Query: 84  GEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKY 143
           GEP G     GPG+ A    + +E+   A  EE++   GE G   EG +E  GE  + KY
Sbjct: 128 GEPGG-----GPGELAPVGPDEKEKGAGAGGEEKKGA-GEGGKDGEGGKE--GEKKNGKY 179

Query: 144 SPGKLRGNQYKKMMTKEELEE 164
                  N    M  ++  E+
Sbjct: 180 EKPPFSYNALIMMAIRQSPEK 200


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 39/116 (33%), Positives = 44/116 (37%), Gaps = 8/116 (6%)

Query: 29   RGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPE----EPGEPAGLGE 82
            RG    P P      P P  E   TG   P  P  P     PAGP       G P G+G 
Sbjct: 1060 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1119

Query: 83   LGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEE-EQDLDGEKG-PSSEGPEEEDG 136
            LG P   GEP   G P        +     R E+ E    GE G P  +GP  +DG
Sbjct: 1120 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDG 1175



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 32/110 (29%), Positives = 38/110 (34%), Gaps = 16/110 (14%)

Query: 41   PPEPAPPAEATGAPAPSRPCA-------------PEPAASPAGPEEPGEPAGLGELGEPA 87
            PP P  PA   GA  P  P               P  + SP    EPG     GE GE  
Sbjct: 1095 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1154

Query: 88   GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDG 136
              G+P  PG P       ++              G+ GP  E GP  +DG
Sbjct: 1155 ESGQPGEPGPPGPKGPTGDDG--PKGNPGPVGFPGDPGPPGEGGPRGQDG 1202



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 36/119 (30%), Positives = 40/119 (33%), Gaps = 20/119 (16%)

Query: 30   GAAASP-----EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELG 84
            G A  P     E    PP PA      GA     P  P     P GP  PG     G  G
Sbjct: 908  GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP--PGAAGEKGVPG 965

Query: 85   E--PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137
            E  P GP   +G   P   P  A    V          DG+KG    P  +G +   GE
Sbjct: 966  EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE-------DGDKGEVGDPGQKGTKGNKGE 1017



 Score = 37.7 bits (86), Expect = 0.005
 Identities = 36/120 (30%), Positives = 40/120 (33%), Gaps = 29/120 (24%)

Query: 28  RRGAAASPEPARAPPEPAP------PAE-----ATGAPAPSRPCAPEPAASPAGPEEPGE 76
           + G    P P  AP +  P      P E       G P       P     PAG   PGE
Sbjct: 876 KEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG--SPGE 933

Query: 77  PAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG 136
               G  G    PG P   G P AA               E+ + GEKGP   GP   DG
Sbjct: 934 RGAAGSGGPIGPPGRPGPQGPPGAA--------------GEKGVPGEKGPI--GPTGRDG 977



 Score = 37.7 bits (86), Expect = 0.005
 Identities = 34/122 (27%), Positives = 41/122 (33%), Gaps = 12/122 (9%)

Query: 29   RGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86
            RG       +  P EP PP     TG   P     P P   P  P  PGE    G+ G  
Sbjct: 1147 RGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN--PGPVGFPGDPGPPGEGGPRGQDGAK 1204

Query: 87   AGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPG 146
               GE   PG P  +P    E              G++GP+     E    G   K  PG
Sbjct: 1205 GDRGEDGEPGQP-GSPGPTGENGPPGPL-------GKRGPAGSPGSEGRQGGKGAKGDPG 1256

Query: 147  KL 148
             +
Sbjct: 1257 AI 1258



 Score = 37.0 bits (84), Expect = 0.008
 Identities = 44/151 (29%), Positives = 50/151 (33%), Gaps = 43/151 (28%)

Query: 29   RGAAASPEPARAPPEPAPP-----AEATGAPAPSRPCAP---EPAASPAGPEEPGEPAGL 80
            RGAA S  P   P  P P      A   G P    P  P   +    P G   P  P G+
Sbjct: 934  RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV 993

Query: 81   ----------------------GELGEPAGPGEPEGP-GDPAAAPAEAEEQAVEAR---- 113
                                  GE G P  PG P GP G P AA A+ E  A   +    
Sbjct: 994  AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG-PIGPVGQPGAAGADGEPGARGPQGHFG 1052

Query: 114  ---QEEEQDLDGEKGP----SSEGPEEEDGE 137
                E  +  +G  GP       GP  E GE
Sbjct: 1053 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1083



 Score = 36.2 bits (82), Expect = 0.014
 Identities = 40/142 (28%), Positives = 52/142 (36%), Gaps = 21/142 (14%)

Query: 26   LVRRGAAASP--EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE----------E 73
            L +RG A SP  E  +          A GAP  + P  P   A   GP+          +
Sbjct: 1231 LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1290

Query: 74   PGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVE----ARQEEEQDLDGEKG-PSS 128
             G P   G+ G P   G P  PG    A A+ E+             EQ   G++G P  
Sbjct: 1291 QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1350

Query: 129  EGPEEEDGE----GFSFKYSPG 146
            +G   + GE    G S    PG
Sbjct: 1351 QGSPGQKGEMGIPGASGPIGPG 1372



 Score = 35.4 bits (80), Expect = 0.024
 Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 29/102 (28%)

Query: 30   GAAASPEPARAPPEPAPPAEA-----TGAPA-------PSRPCAPEPAA----------- 66
            G   +P P   P +P PP E       GA         P +P +P P             
Sbjct: 1175 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1234

Query: 67   SPAG-PEEPGEPAGLGELGEP---AGPGE--PEGPGDPAAAP 102
             PAG P   G   G G  G+P     PG+  P GP  PA  P
Sbjct: 1235 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP 1276



 Score = 35.0 bits (79), Expect = 0.031
 Identities = 29/103 (28%), Positives = 35/103 (33%), Gaps = 22/103 (21%)

Query: 43  EPAPPAE-----ATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE------ 91
           EP PP +       G P P     P     P G  +PG P   G  G P  PG+      
Sbjct: 558 EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG--KPGLPGMPGSDGPPGHPGKEGPPGT 615

Query: 92  -----PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE 129
                P GP  P   P     + V+      + L G KG   E
Sbjct: 616 KGNQGPSGPQGPLGYPGPRGVKGVDG----IRGLKGHKGEKGE 654



 Score = 35.0 bits (79), Expect = 0.031
 Identities = 25/81 (30%), Positives = 28/81 (34%), Gaps = 13/81 (16%)

Query: 29  RGAAASPEPARAPPEPAPPAEA-----TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGEL 83
           +G    P     P  P    E      TG P P     P+ AA   GP        +GE 
Sbjct: 805 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP--------MGER 856

Query: 84  GEPAGPGEPEGPGDPAAAPAE 104
           G P  PG P   G P  A  E
Sbjct: 857 GHPGPPGPPGEQGLPGTAGKE 877



 Score = 35.0 bits (79), Expect = 0.031
 Identities = 36/109 (33%), Positives = 42/109 (38%), Gaps = 14/109 (12%)

Query: 30   GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGL-GELGEPAG 88
            G + SP     P    P  E        +P  P P   P GP     P G  G +G P  
Sbjct: 1130 GESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG-PKGPTGDDGPKGNPGPVGFPGD 1188

Query: 89   PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDG 136
            PG P G G P       ++ A   R E     DGE G P S GP  E+G
Sbjct: 1189 PG-PPGEGGP-----RGQDGAKGDRGE-----DGEPGQPGSPGPTGENG 1226



 Score = 34.3 bits (77), Expect = 0.053
 Identities = 37/121 (30%), Positives = 42/121 (34%), Gaps = 12/121 (9%)

Query: 35  PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG 94
           P   R  P P  P    G P P  P  P P      P  PG+   +G  G+   PG P  
Sbjct: 786 PPGERGLPGPQGP---NGFPGPKGP--PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 840

Query: 95  PGDPAAA----PAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG-EGFSFKYSPGKLR 149
            G   AA    P              EQ L G  G   EG + + G  G   K  P  LR
Sbjct: 841 VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG--KEGTKGDPGPPGAPGKDGPAGLR 898

Query: 150 G 150
           G
Sbjct: 899 G 899



 Score = 33.5 bits (75), Expect = 0.091
 Identities = 33/117 (28%), Positives = 39/117 (33%), Gaps = 29/117 (24%)

Query: 29  RGAAASPEPA---RAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE 85
           +G  A  EP      PP P  PA   G P            +P    +PGE    G  G 
Sbjct: 299 KGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQ--------GNPGPVGDPGERGPPGRAGL 350

Query: 86  PAGPGEPEGPG----------------DPAAAPAEAEEQAVEARQEEEQDLDGEKGP 126
           P   G P  PG                 P  A  EA+ QA+   Q+    L G  GP
Sbjct: 351 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAI--LQQARLALRGPPGP 405



 Score = 32.3 bits (72), Expect = 0.20
 Identities = 32/97 (32%), Positives = 39/97 (40%), Gaps = 19/97 (19%)

Query: 52  GAPAPSRPCAPEPAASPAGPE-EPGEPAGLGE---LGEPAGPGEP--EGP----GDPAAA 101
           G P       PE      GP  +PG P  +GE   LG P  PG P  +GP    G P   
Sbjct: 674 GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 733

Query: 102 PAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGE 137
            A  E+ A        + L G+ GP  E GP    G+
Sbjct: 734 GASGEKGA--------RGLSGKSGPRGERGPTGPRGQ 762



 Score = 32.3 bits (72), Expect = 0.20
 Identities = 29/102 (28%), Positives = 34/102 (33%), Gaps = 10/102 (9%)

Query: 41  PPEPAPPAEATGAPAP----SRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPG 96
           PP    P  A G   P      P  P P      P   G+    G+ G P  PG+ +GP 
Sbjct: 837 PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK-DGPA 895

Query: 97  DPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDGE 137
                P E               L G +GPS   GP    GE
Sbjct: 896 GLRGFPGERGLPGTAG----GPGLKGNEGPSGPPGPAGSPGE 933



 Score = 31.2 bits (69), Expect = 0.45
 Identities = 33/121 (27%), Positives = 44/121 (36%), Gaps = 21/121 (17%)

Query: 29   RGAAASPEPARAPPEPAPPAEATGAPAPSRPC---APEPAASPAGPE------EPGEPAG 79
            +G    P P  +P +        G P  S P     P     PAGP+       PG P  
Sbjct: 1342 KGDRGLPGPQGSPGQKGE----MGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK- 1396

Query: 80   LGELGEPAGPGEPEGPGD-----PAAAPAEAEEQAVEAR-QEEEQDLDGEKGPSSEGPEE 133
             GE G    PG P  PG+     P   P +       +R  +E++ +     P S G  E
Sbjct: 1397 -GEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLE 1455

Query: 134  E 134
            E
Sbjct: 1456 E 1456



 Score = 30.8 bits (68), Expect = 0.59
 Identities = 33/132 (25%), Positives = 42/132 (31%), Gaps = 12/132 (9%)

Query: 30  GAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87
           GA   P P     E     E    G P  S    P     P GP     P G+  +  P 
Sbjct: 491 GAQGLPGPPGEDGERGDDGEIGPRGLPGES---GPRGLLGPKGPPGIPGPPGVRGMDGPQ 547

Query: 88  GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL--DGEKGPSSEG-----PEEEDGEGFS 140
           GP    GP      P +      +     +  +   GEKGP  +      P  +   G  
Sbjct: 548 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 607

Query: 141 FKYSPGKLRGNQ 152
            K  P   +GNQ
Sbjct: 608 GKEGPPGTKGNQ 619



 Score = 29.3 bits (64), Expect = 1.7
 Identities = 30/97 (30%), Positives = 33/97 (34%), Gaps = 25/97 (25%)

Query: 62  PEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG-PGDPAAAPAEAEEQAVEARQ------ 114
           P P   P  P   GE   LG    P GP  P+G  G P  A       A  AR       
Sbjct: 412 PGPLGQPGSPGLKGESGDLG----PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG 467

Query: 115 -------EEEQDLDGEKGPSSE-------GPEEEDGE 137
                  +    L GEKG   +       GP  EDGE
Sbjct: 468 VKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE 504



 Score = 29.3 bits (64), Expect = 1.7
 Identities = 27/105 (25%), Positives = 36/105 (34%), Gaps = 15/105 (14%)

Query: 37  PARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEE-------PGEPAGLGELGEPA 87
           P   P  P PP      G   P     P+    P G +        PG    +G  GE  
Sbjct: 528 PKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKG 587

Query: 88  GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGP 131
             G+P  PG P      ++       +E      G +GPS  +GP
Sbjct: 588 PQGKPGLPGMPG-----SDGPPGHPGKEGPPGTKGNQGPSGPQGP 627



 Score = 28.5 bits (62), Expect = 2.9
 Identities = 25/95 (26%), Positives = 31/95 (32%), Gaps = 5/95 (5%)

Query: 47  PAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAE 106
           P    G   P        A   +G + P  P G   L  P GP    GP  P   P + +
Sbjct: 756 PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK-D 814

Query: 107 EQAVEARQEEEQDLDGEKGPSSE----GPEEEDGE 137
                  Q  E    G+ GP       GP+   GE
Sbjct: 815 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGE 849



 Score = 28.1 bits (61), Expect = 3.8
 Identities = 24/83 (28%), Positives = 32/83 (38%), Gaps = 14/83 (16%)

Query: 68  PAGPEEPGEPAGLGELGEPAGPGEPEGPGD-----PAAAPAEAEEQAVEARQEEE----- 117
           P  P E G     G  G P  PGE    GD     P   P E+  + +   +        
Sbjct: 478 PGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGP 537

Query: 118 ---QDLDGEKGP-SSEGPEEEDG 136
              + +DG +GP  S GP+ E G
Sbjct: 538 PGVRGMDGPQGPKGSLGPQGEPG 560



 Score = 27.3 bits (59), Expect = 6.5
 Identities = 27/102 (26%), Positives = 33/102 (32%), Gaps = 28/102 (27%)

Query: 23  AWLLVRRGAAASPEPARAPPEPAPPAEA-----TGAPAP--SRPCAPEPAASPAGPEEP- 74
           A L+   G   +P P   P E  PP  A      GAP P  +    P    S  G + P 
Sbjct: 321 AGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPV 380

Query: 75  --------------------GEPAGLGELGEPAGPGEPEGPG 96
                               G P  +G  G P   G+P  PG
Sbjct: 381 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG 422



 Score = 26.9 bits (58), Expect = 8.5
 Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 1/61 (1%)

Query: 43  EPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGEPAGPGEPEGPGDPAAA 101
           +P P  E     +   P   E A  P G + E GEPA L       GP  PEGP      
Sbjct: 267 DPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGP 326

Query: 102 P 102
           P
Sbjct: 327 P 327


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 39/116 (33%), Positives = 44/116 (37%), Gaps = 8/116 (6%)

Query: 29   RGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPE----EPGEPAGLGE 82
            RG    P P      P P  E   TG   P  P  P     PAGP       G P G+G 
Sbjct: 1039 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1098

Query: 83   LGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEE-EQDLDGEKG-PSSEGPEEEDG 136
            LG P   GEP   G P        +     R E+ E    GE G P  +GP  +DG
Sbjct: 1099 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDG 1154



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 32/110 (29%), Positives = 38/110 (34%), Gaps = 16/110 (14%)

Query: 41   PPEPAPPAEATGAPAPSRPCA-------------PEPAASPAGPEEPGEPAGLGELGEPA 87
            PP P  PA   GA  P  P               P  + SP    EPG     GE GE  
Sbjct: 1074 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1133

Query: 88   GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDG 136
              G+P  PG P       ++              G+ GP  E GP  +DG
Sbjct: 1134 ESGQPGEPGPPGPKGPTGDDG--PKGNPGPVGFPGDPGPPGEGGPRGQDG 1181



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 36/119 (30%), Positives = 40/119 (33%), Gaps = 20/119 (16%)

Query: 30  GAAASP-----EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELG 84
           G A  P     E    PP PA      GA     P  P     P GP  PG     G  G
Sbjct: 887 GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP--PGAAGEKGVPG 944

Query: 85  E--PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137
           E  P GP   +G   P   P  A    V          DG+KG    P  +G +   GE
Sbjct: 945 EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE-------DGDKGEVGDPGQKGTKGNKGE 996



 Score = 37.7 bits (86), Expect = 0.005
 Identities = 36/120 (30%), Positives = 40/120 (33%), Gaps = 29/120 (24%)

Query: 28  RRGAAASPEPARAPPEPAP------PAE-----ATGAPAPSRPCAPEPAASPAGPEEPGE 76
           + G    P P  AP +  P      P E       G P       P     PAG   PGE
Sbjct: 855 KEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG--SPGE 912

Query: 77  PAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG 136
               G  G    PG P   G P AA               E+ + GEKGP   GP   DG
Sbjct: 913 RGAAGSGGPIGPPGRPGPQGPPGAA--------------GEKGVPGEKGPI--GPTGRDG 956



 Score = 37.7 bits (86), Expect = 0.005
 Identities = 34/122 (27%), Positives = 41/122 (33%), Gaps = 12/122 (9%)

Query: 29   RGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86
            RG       +  P EP PP     TG   P     P P   P  P  PGE    G+ G  
Sbjct: 1126 RGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN--PGPVGFPGDPGPPGEGGPRGQDGAK 1183

Query: 87   AGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPG 146
               GE   PG P  +P    E              G++GP+     E    G   K  PG
Sbjct: 1184 GDRGEDGEPGQP-GSPGPTGENGPPGPL-------GKRGPAGSPGSEGRQGGKGAKGDPG 1235

Query: 147  KL 148
             +
Sbjct: 1236 AI 1237



 Score = 37.0 bits (84), Expect = 0.008
 Identities = 44/151 (29%), Positives = 50/151 (33%), Gaps = 43/151 (28%)

Query: 29   RGAAASPEPARAPPEPAPP-----AEATGAPAPSRPCAP---EPAASPAGPEEPGEPAGL 80
            RGAA S  P   P  P P      A   G P    P  P   +    P G   P  P G+
Sbjct: 913  RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV 972

Query: 81   ----------------------GELGEPAGPGEPEGP-GDPAAAPAEAEEQAVEAR---- 113
                                  GE G P  PG P GP G P AA A+ E  A   +    
Sbjct: 973  AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG-PIGPVGQPGAAGADGEPGARGPQGHFG 1031

Query: 114  ---QEEEQDLDGEKGP----SSEGPEEEDGE 137
                E  +  +G  GP       GP  E GE
Sbjct: 1032 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1062



 Score = 36.2 bits (82), Expect = 0.014
 Identities = 40/142 (28%), Positives = 52/142 (36%), Gaps = 21/142 (14%)

Query: 26   LVRRGAAASP--EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE----------E 73
            L +RG A SP  E  +          A GAP  + P  P   A   GP+          +
Sbjct: 1210 LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1269

Query: 74   PGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVE----ARQEEEQDLDGEKG-PSS 128
             G P   G+ G P   G P  PG    A A+ E+             EQ   G++G P  
Sbjct: 1270 QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1329

Query: 129  EGPEEEDGE----GFSFKYSPG 146
            +G   + GE    G S    PG
Sbjct: 1330 QGSPGQKGEMGIPGASGPIGPG 1351



 Score = 35.4 bits (80), Expect = 0.024
 Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 29/102 (28%)

Query: 30   GAAASPEPARAPPEPAPPAEA-----TGAPA-------PSRPCAPEPAA----------- 66
            G   +P P   P +P PP E       GA         P +P +P P             
Sbjct: 1154 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1213

Query: 67   SPAG-PEEPGEPAGLGELGEP---AGPGE--PEGPGDPAAAP 102
             PAG P   G   G G  G+P     PG+  P GP  PA  P
Sbjct: 1214 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP 1255



 Score = 35.0 bits (79), Expect = 0.031
 Identities = 29/103 (28%), Positives = 35/103 (33%), Gaps = 22/103 (21%)

Query: 43  EPAPPAE-----ATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE------ 91
           EP PP +       G P P     P     P G  +PG P   G  G P  PG+      
Sbjct: 537 EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG--KPGLPGMPGSDGPPGHPGKEGPPGT 594

Query: 92  -----PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE 129
                P GP  P   P     + V+      + L G KG   E
Sbjct: 595 KGNQGPSGPQGPLGYPGPRGVKGVDG----IRGLKGHKGEKGE 633



 Score = 35.0 bits (79), Expect = 0.031
 Identities = 25/81 (30%), Positives = 28/81 (34%), Gaps = 13/81 (16%)

Query: 29  RGAAASPEPARAPPEPAPPAEA-----TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGEL 83
           +G    P     P  P    E      TG P P     P+ AA   GP        +GE 
Sbjct: 784 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP--------MGER 835

Query: 84  GEPAGPGEPEGPGDPAAAPAE 104
           G P  PG P   G P  A  E
Sbjct: 836 GHPGPPGPPGEQGLPGTAGKE 856



 Score = 35.0 bits (79), Expect = 0.031
 Identities = 36/109 (33%), Positives = 42/109 (38%), Gaps = 14/109 (12%)

Query: 30   GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGL-GELGEPAG 88
            G + SP     P    P  E        +P  P P   P GP     P G  G +G P  
Sbjct: 1109 GESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG-PKGPTGDDGPKGNPGPVGFPGD 1167

Query: 89   PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDG 136
            PG P G G P       ++ A   R E     DGE G P S GP  E+G
Sbjct: 1168 PG-PPGEGGP-----RGQDGAKGDRGE-----DGEPGQPGSPGPTGENG 1205



 Score = 34.3 bits (77), Expect = 0.053
 Identities = 37/121 (30%), Positives = 42/121 (34%), Gaps = 12/121 (9%)

Query: 35  PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG 94
           P   R  P P  P    G P P  P  P P      P  PG+   +G  G+   PG P  
Sbjct: 765 PPGERGLPGPQGP---NGFPGPKGP--PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 819

Query: 95  PGDPAAA----PAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG-EGFSFKYSPGKLR 149
            G   AA    P              EQ L G  G   EG + + G  G   K  P  LR
Sbjct: 820 VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG--KEGTKGDPGPPGAPGKDGPAGLR 877

Query: 150 G 150
           G
Sbjct: 878 G 878



 Score = 33.9 bits (76), Expect = 0.069
 Identities = 23/76 (30%), Positives = 27/76 (35%), Gaps = 7/76 (9%)

Query: 28  RRGAAASPEPARAPPEPAPPAEATGAP-----APSRPCAPEPAASPAGPEEPGEPAGLGE 82
           +R     P     P    P ++A   P         P   EP     GP  P  PAGL  
Sbjct: 245 QRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGL-- 302

Query: 83  LGEPAGPGEPEGPGDP 98
           +G P   G P   GDP
Sbjct: 303 IGPPGIQGNPGPVGDP 318



 Score = 33.5 bits (75), Expect = 0.091
 Identities = 33/117 (28%), Positives = 39/117 (33%), Gaps = 29/117 (24%)

Query: 29  RGAAASPEPA---RAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE 85
           +G  A  EP      PP P  PA   G P            +P    +PGE    G  G 
Sbjct: 278 KGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQ--------GNPGPVGDPGERGPPGRAGL 329

Query: 86  PAGPGEPEGPG----------------DPAAAPAEAEEQAVEARQEEEQDLDGEKGP 126
           P   G P  PG                 P  A  EA+ QA+   Q+    L G  GP
Sbjct: 330 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAI--LQQARLALRGPPGP 384



 Score = 32.3 bits (72), Expect = 0.20
 Identities = 32/97 (32%), Positives = 39/97 (40%), Gaps = 19/97 (19%)

Query: 52  GAPAPSRPCAPEPAASPAGPE-EPGEPAGLGE---LGEPAGPGEP--EGP----GDPAAA 101
           G P       PE      GP  +PG P  +GE   LG P  PG P  +GP    G P   
Sbjct: 653 GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 712

Query: 102 PAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGE 137
            A  E+ A        + L G+ GP  E GP    G+
Sbjct: 713 GASGEKGA--------RGLSGKSGPRGERGPTGPRGQ 741



 Score = 32.3 bits (72), Expect = 0.20
 Identities = 29/102 (28%), Positives = 34/102 (33%), Gaps = 10/102 (9%)

Query: 41  PPEPAPPAEATGAPAP----SRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPG 96
           PP    P  A G   P      P  P P      P   G+    G+ G P  PG+ +GP 
Sbjct: 816 PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK-DGPA 874

Query: 97  DPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDGE 137
                P E               L G +GPS   GP    GE
Sbjct: 875 GLRGFPGERGLPGTAG----GPGLKGNEGPSGPPGPAGSPGE 912



 Score = 31.2 bits (69), Expect = 0.45
 Identities = 33/121 (27%), Positives = 44/121 (36%), Gaps = 21/121 (17%)

Query: 29   RGAAASPEPARAPPEPAPPAEATGAPAPSRPC---APEPAASPAGPE------EPGEPAG 79
            +G    P P  +P +        G P  S P     P     PAGP+       PG P  
Sbjct: 1321 KGDRGLPGPQGSPGQKGE----MGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK- 1375

Query: 80   LGELGEPAGPGEPEGPGD-----PAAAPAEAEEQAVEAR-QEEEQDLDGEKGPSSEGPEE 133
             GE G    PG P  PG+     P   P +       +R  +E++ +     P S G  E
Sbjct: 1376 -GEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLE 1434

Query: 134  E 134
            E
Sbjct: 1435 E 1435



 Score = 30.8 bits (68), Expect = 0.59
 Identities = 33/132 (25%), Positives = 42/132 (31%), Gaps = 12/132 (9%)

Query: 30  GAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87
           GA   P P     E     E    G P  S    P     P GP     P G+  +  P 
Sbjct: 470 GAQGLPGPPGEDGERGDDGEIGPRGLPGES---GPRGLLGPKGPPGIPGPPGVRGMDGPQ 526

Query: 88  GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL--DGEKGPSSEG-----PEEEDGEGFS 140
           GP    GP      P +      +     +  +   GEKGP  +      P  +   G  
Sbjct: 527 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 586

Query: 141 FKYSPGKLRGNQ 152
            K  P   +GNQ
Sbjct: 587 GKEGPPGTKGNQ 598



 Score = 29.3 bits (64), Expect = 1.7
 Identities = 30/97 (30%), Positives = 33/97 (34%), Gaps = 25/97 (25%)

Query: 62  PEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG-PGDPAAAPAEAEEQAVEARQ------ 114
           P P   P  P   GE   LG    P GP  P+G  G P  A       A  AR       
Sbjct: 391 PGPLGQPGSPGLKGESGDLG----PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG 446

Query: 115 -------EEEQDLDGEKGPSSE-------GPEEEDGE 137
                  +    L GEKG   +       GP  EDGE
Sbjct: 447 VKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE 483



 Score = 29.3 bits (64), Expect = 1.7
 Identities = 27/105 (25%), Positives = 36/105 (34%), Gaps = 15/105 (14%)

Query: 37  PARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEE-------PGEPAGLGELGEPA 87
           P   P  P PP      G   P     P+    P G +        PG    +G  GE  
Sbjct: 507 PKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKG 566

Query: 88  GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGP 131
             G+P  PG P      ++       +E      G +GPS  +GP
Sbjct: 567 PQGKPGLPGMPG-----SDGPPGHPGKEGPPGTKGNQGPSGPQGP 606



 Score = 28.5 bits (62), Expect = 2.9
 Identities = 25/95 (26%), Positives = 31/95 (32%), Gaps = 5/95 (5%)

Query: 47  PAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAE 106
           P    G   P        A   +G + P  P G   L  P GP    GP  P   P + +
Sbjct: 735 PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK-D 793

Query: 107 EQAVEARQEEEQDLDGEKGPSSE----GPEEEDGE 137
                  Q  E    G+ GP       GP+   GE
Sbjct: 794 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGE 828



 Score = 28.1 bits (61), Expect = 3.8
 Identities = 24/83 (28%), Positives = 32/83 (38%), Gaps = 14/83 (16%)

Query: 68  PAGPEEPGEPAGLGELGEPAGPGEPEGPGD-----PAAAPAEAEEQAVEARQEEE----- 117
           P  P E G     G  G P  PGE    GD     P   P E+  + +   +        
Sbjct: 457 PGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGP 516

Query: 118 ---QDLDGEKGP-SSEGPEEEDG 136
              + +DG +GP  S GP+ E G
Sbjct: 517 PGVRGMDGPQGPKGSLGPQGEPG 539



 Score = 27.3 bits (59), Expect = 6.5
 Identities = 27/102 (26%), Positives = 33/102 (32%), Gaps = 28/102 (27%)

Query: 23  AWLLVRRGAAASPEPARAPPEPAPPAEA-----TGAPAP--SRPCAPEPAASPAGPEEP- 74
           A L+   G   +P P   P E  PP  A      GAP P  +    P    S  G + P 
Sbjct: 300 AGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPV 359

Query: 75  --------------------GEPAGLGELGEPAGPGEPEGPG 96
                               G P  +G  G P   G+P  PG
Sbjct: 360 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG 401


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 39/116 (33%), Positives = 44/116 (37%), Gaps = 8/116 (6%)

Query: 29   RGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPE----EPGEPAGLGE 82
            RG    P P      P P  E   TG   P  P  P     PAGP       G P G+G 
Sbjct: 1146 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1205

Query: 83   LGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEE-EQDLDGEKG-PSSEGPEEEDG 136
            LG P   GEP   G P        +     R E+ E    GE G P  +GP  +DG
Sbjct: 1206 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDG 1261



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 32/110 (29%), Positives = 38/110 (34%), Gaps = 16/110 (14%)

Query: 41   PPEPAPPAEATGAPAPSRPCA-------------PEPAASPAGPEEPGEPAGLGELGEPA 87
            PP P  PA   GA  P  P               P  + SP    EPG     GE GE  
Sbjct: 1181 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1240

Query: 88   GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDG 136
              G+P  PG P       ++              G+ GP  E GP  +DG
Sbjct: 1241 ESGQPGEPGPPGPKGPTGDDG--PKGNPGPVGFPGDPGPPGEGGPRGQDG 1288



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 36/119 (30%), Positives = 40/119 (33%), Gaps = 20/119 (16%)

Query: 30   GAAASP-----EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELG 84
            G A  P     E    PP PA      GA     P  P     P GP  PG     G  G
Sbjct: 994  GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP--PGAAGEKGVPG 1051

Query: 85   E--PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137
            E  P GP   +G   P   P  A    V          DG+KG    P  +G +   GE
Sbjct: 1052 EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE-------DGDKGEVGDPGQKGTKGNKGE 1103



 Score = 37.7 bits (86), Expect = 0.005
 Identities = 36/120 (30%), Positives = 40/120 (33%), Gaps = 29/120 (24%)

Query: 28   RRGAAASPEPARAPPEPAP------PAE-----ATGAPAPSRPCAPEPAASPAGPEEPGE 76
            + G    P P  AP +  P      P E       G P       P     PAG   PGE
Sbjct: 962  KEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG--SPGE 1019

Query: 77   PAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG 136
                G  G    PG P   G P AA               E+ + GEKGP   GP   DG
Sbjct: 1020 RGAAGSGGPIGPPGRPGPQGPPGAA--------------GEKGVPGEKGPI--GPTGRDG 1063



 Score = 37.7 bits (86), Expect = 0.005
 Identities = 34/122 (27%), Positives = 41/122 (33%), Gaps = 12/122 (9%)

Query: 29   RGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86
            RG       +  P EP PP     TG   P     P P   P  P  PGE    G+ G  
Sbjct: 1233 RGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN--PGPVGFPGDPGPPGEGGPRGQDGAK 1290

Query: 87   AGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPG 146
               GE   PG P  +P    E              G++GP+     E    G   K  PG
Sbjct: 1291 GDRGEDGEPGQP-GSPGPTGENGPPGPL-------GKRGPAGSPGSEGRQGGKGAKGDPG 1342

Query: 147  KL 148
             +
Sbjct: 1343 AI 1344



 Score = 37.0 bits (84), Expect = 0.008
 Identities = 44/151 (29%), Positives = 50/151 (33%), Gaps = 43/151 (28%)

Query: 29   RGAAASPEPARAPPEPAPP-----AEATGAPAPSRPCAP---EPAASPAGPEEPGEPAGL 80
            RGAA S  P   P  P P      A   G P    P  P   +    P G   P  P G+
Sbjct: 1020 RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV 1079

Query: 81   ----------------------GELGEPAGPGEPEGP-GDPAAAPAEAEEQAVEAR---- 113
                                  GE G P  PG P GP G P AA A+ E  A   +    
Sbjct: 1080 AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG-PIGPVGQPGAAGADGEPGARGPQGHFG 1138

Query: 114  ---QEEEQDLDGEKGP----SSEGPEEEDGE 137
                E  +  +G  GP       GP  E GE
Sbjct: 1139 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1169



 Score = 36.2 bits (82), Expect = 0.014
 Identities = 40/142 (28%), Positives = 52/142 (36%), Gaps = 21/142 (14%)

Query: 26   LVRRGAAASP--EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE----------E 73
            L +RG A SP  E  +          A GAP  + P  P   A   GP+          +
Sbjct: 1317 LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1376

Query: 74   PGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVE----ARQEEEQDLDGEKG-PSS 128
             G P   G+ G P   G P  PG    A A+ E+             EQ   G++G P  
Sbjct: 1377 QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1436

Query: 129  EGPEEEDGE----GFSFKYSPG 146
            +G   + GE    G S    PG
Sbjct: 1437 QGSPGQKGEMGIPGASGPIGPG 1458



 Score = 35.4 bits (80), Expect = 0.024
 Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 29/102 (28%)

Query: 30   GAAASPEPARAPPEPAPPAEA-----TGAPA-------PSRPCAPEPAA----------- 66
            G   +P P   P +P PP E       GA         P +P +P P             
Sbjct: 1261 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1320

Query: 67   SPAG-PEEPGEPAGLGELGEP---AGPGE--PEGPGDPAAAP 102
             PAG P   G   G G  G+P     PG+  P GP  PA  P
Sbjct: 1321 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP 1362



 Score = 35.0 bits (79), Expect = 0.031
 Identities = 29/103 (28%), Positives = 35/103 (33%), Gaps = 22/103 (21%)

Query: 43  EPAPPAE-----ATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE------ 91
           EP PP +       G P P     P     P G  +PG P   G  G P  PG+      
Sbjct: 644 EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG--KPGLPGMPGSDGPPGHPGKEGPPGT 701

Query: 92  -----PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE 129
                P GP  P   P     + V+      + L G KG   E
Sbjct: 702 KGNQGPSGPQGPLGYPGPRGVKGVDG----IRGLKGHKGEKGE 740



 Score = 35.0 bits (79), Expect = 0.031
 Identities = 25/81 (30%), Positives = 28/81 (34%), Gaps = 13/81 (16%)

Query: 29  RGAAASPEPARAPPEPAPPAEA-----TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGEL 83
           +G    P     P  P    E      TG P P     P+ AA   GP        +GE 
Sbjct: 891 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP--------MGER 942

Query: 84  GEPAGPGEPEGPGDPAAAPAE 104
           G P  PG P   G P  A  E
Sbjct: 943 GHPGPPGPPGEQGLPGTAGKE 963



 Score = 35.0 bits (79), Expect = 0.031
 Identities = 36/109 (33%), Positives = 42/109 (38%), Gaps = 14/109 (12%)

Query: 30   GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGL-GELGEPAG 88
            G + SP     P    P  E        +P  P P   P GP     P G  G +G P  
Sbjct: 1216 GESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG-PKGPTGDDGPKGNPGPVGFPGD 1274

Query: 89   PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDG 136
            PG P G G P       ++ A   R E     DGE G P S GP  E+G
Sbjct: 1275 PG-PPGEGGP-----RGQDGAKGDRGE-----DGEPGQPGSPGPTGENG 1312



 Score = 34.3 bits (77), Expect = 0.053
 Identities = 37/121 (30%), Positives = 42/121 (34%), Gaps = 12/121 (9%)

Query: 35  PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG 94
           P   R  P P  P    G P P  P  P P      P  PG+   +G  G+   PG P  
Sbjct: 872 PPGERGLPGPQGP---NGFPGPKGP--PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 926

Query: 95  PGDPAAA----PAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG-EGFSFKYSPGKLR 149
            G   AA    P              EQ L G  G   EG + + G  G   K  P  LR
Sbjct: 927 VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG--KEGTKGDPGPPGAPGKDGPAGLR 984

Query: 150 G 150
           G
Sbjct: 985 G 985



 Score = 33.5 bits (75), Expect = 0.091
 Identities = 33/117 (28%), Positives = 39/117 (33%), Gaps = 29/117 (24%)

Query: 29  RGAAASPEPA---RAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE 85
           +G  A  EP      PP P  PA   G P            +P    +PGE    G  G 
Sbjct: 385 KGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQ--------GNPGPVGDPGERGPPGRAGL 436

Query: 86  PAGPGEPEGPG----------------DPAAAPAEAEEQAVEARQEEEQDLDGEKGP 126
           P   G P  PG                 P  A  EA+ QA+   Q+    L G  GP
Sbjct: 437 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAI--LQQARLALRGPPGP 491



 Score = 32.3 bits (72), Expect = 0.20
 Identities = 32/97 (32%), Positives = 39/97 (40%), Gaps = 19/97 (19%)

Query: 52  GAPAPSRPCAPEPAASPAGPE-EPGEPAGLGE---LGEPAGPGEP--EGP----GDPAAA 101
           G P       PE      GP  +PG P  +GE   LG P  PG P  +GP    G P   
Sbjct: 760 GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 819

Query: 102 PAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGE 137
            A  E+ A        + L G+ GP  E GP    G+
Sbjct: 820 GASGEKGA--------RGLSGKSGPRGERGPTGPRGQ 848



 Score = 32.3 bits (72), Expect = 0.20
 Identities = 29/102 (28%), Positives = 34/102 (33%), Gaps = 10/102 (9%)

Query: 41   PPEPAPPAEATGAPAP----SRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPG 96
            PP    P  A G   P      P  P P      P   G+    G+ G P  PG+ +GP 
Sbjct: 923  PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK-DGPA 981

Query: 97   DPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDGE 137
                 P E               L G +GPS   GP    GE
Sbjct: 982  GLRGFPGERGLPGTAG----GPGLKGNEGPSGPPGPAGSPGE 1019



 Score = 31.2 bits (69), Expect = 0.45
 Identities = 33/121 (27%), Positives = 44/121 (36%), Gaps = 21/121 (17%)

Query: 29   RGAAASPEPARAPPEPAPPAEATGAPAPSRPC---APEPAASPAGPE------EPGEPAG 79
            +G    P P  +P +        G P  S P     P     PAGP+       PG P  
Sbjct: 1428 KGDRGLPGPQGSPGQKGE----MGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK- 1482

Query: 80   LGELGEPAGPGEPEGPGD-----PAAAPAEAEEQAVEAR-QEEEQDLDGEKGPSSEGPEE 133
             GE G    PG P  PG+     P   P +       +R  +E++ +     P S G  E
Sbjct: 1483 -GEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLE 1541

Query: 134  E 134
            E
Sbjct: 1542 E 1542



 Score = 30.8 bits (68), Expect = 0.59
 Identities = 33/132 (25%), Positives = 42/132 (31%), Gaps = 12/132 (9%)

Query: 30  GAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87
           GA   P P     E     E    G P  S    P     P GP     P G+  +  P 
Sbjct: 577 GAQGLPGPPGEDGERGDDGEIGPRGLPGES---GPRGLLGPKGPPGIPGPPGVRGMDGPQ 633

Query: 88  GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL--DGEKGPSSEG-----PEEEDGEGFS 140
           GP    GP      P +      +     +  +   GEKGP  +      P  +   G  
Sbjct: 634 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 693

Query: 141 FKYSPGKLRGNQ 152
            K  P   +GNQ
Sbjct: 694 GKEGPPGTKGNQ 705



 Score = 29.3 bits (64), Expect = 1.7
 Identities = 30/97 (30%), Positives = 33/97 (34%), Gaps = 25/97 (25%)

Query: 62  PEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG-PGDPAAAPAEAEEQAVEARQ------ 114
           P P   P  P   GE   LG    P GP  P+G  G P  A       A  AR       
Sbjct: 498 PGPLGQPGSPGLKGESGDLG----PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG 553

Query: 115 -------EEEQDLDGEKGPSSE-------GPEEEDGE 137
                  +    L GEKG   +       GP  EDGE
Sbjct: 554 VKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE 590



 Score = 29.3 bits (64), Expect = 1.7
 Identities = 27/105 (25%), Positives = 36/105 (34%), Gaps = 15/105 (14%)

Query: 37  PARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEE-------PGEPAGLGELGEPA 87
           P   P  P PP      G   P     P+    P G +        PG    +G  GE  
Sbjct: 614 PKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKG 673

Query: 88  GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGP 131
             G+P  PG P      ++       +E      G +GPS  +GP
Sbjct: 674 PQGKPGLPGMPG-----SDGPPGHPGKEGPPGTKGNQGPSGPQGP 713



 Score = 28.5 bits (62), Expect = 2.9
 Identities = 22/70 (31%), Positives = 25/70 (35%), Gaps = 1/70 (1%)

Query: 32  AASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEE-PGEPAGLGELGEPAGPG 90
           AA+  P     E   PA          P  PE  A   GP    G P  +G+ GE   PG
Sbjct: 373 AAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG 432

Query: 91  EPEGPGDPAA 100
               PG   A
Sbjct: 433 RAGLPGSDGA 442



 Score = 28.5 bits (62), Expect = 2.9
 Identities = 25/95 (26%), Positives = 31/95 (32%), Gaps = 5/95 (5%)

Query: 47  PAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAE 106
           P    G   P        A   +G + P  P G   L  P GP    GP  P   P + +
Sbjct: 842 PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK-D 900

Query: 107 EQAVEARQEEEQDLDGEKGPSSE----GPEEEDGE 137
                  Q  E    G+ GP       GP+   GE
Sbjct: 901 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGE 935



 Score = 28.1 bits (61), Expect = 3.8
 Identities = 24/83 (28%), Positives = 32/83 (38%), Gaps = 14/83 (16%)

Query: 68  PAGPEEPGEPAGLGELGEPAGPGEPEGPGD-----PAAAPAEAEEQAVEARQEEE----- 117
           P  P E G     G  G P  PGE    GD     P   P E+  + +   +        
Sbjct: 564 PGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGP 623

Query: 118 ---QDLDGEKGP-SSEGPEEEDG 136
              + +DG +GP  S GP+ E G
Sbjct: 624 PGVRGMDGPQGPKGSLGPQGEPG 646



 Score = 27.3 bits (59), Expect = 6.5
 Identities = 27/102 (26%), Positives = 33/102 (32%), Gaps = 28/102 (27%)

Query: 23  AWLLVRRGAAASPEPARAPPEPAPPAEA-----TGAPAP--SRPCAPEPAASPAGPEEP- 74
           A L+   G   +P P   P E  PP  A      GAP P  +    P    S  G + P 
Sbjct: 407 AGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPV 466

Query: 75  --------------------GEPAGLGELGEPAGPGEPEGPG 96
                               G P  +G  G P   G+P  PG
Sbjct: 467 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG 508


>gi|194578898 hypothetical protein LOC100170841 [Homo sapiens]
          Length = 379

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 41/129 (31%), Positives = 54/129 (41%), Gaps = 32/129 (24%)

Query: 38  ARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPG---EPEG 94
           A APP PAP  E    PA S P   EP++ P     P  PAGL    EPAGPG    P  
Sbjct: 154 ASAPPRPAPGLEPQRGPAASPP--QEPSSRP-----PSPPAGLST--EPAGPGTAPRPFL 204

Query: 95  PGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDGEGFSFKYSPGKLRGNQY 153
           PG PA                   ++DG   P++ E P            +PG LR   +
Sbjct: 205 PGQPA-------------------EVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHF 245

Query: 154 KKMMTKEEL 162
            +++ + +L
Sbjct: 246 DRLIRRSKL 254



 Score = 37.4 bits (85), Expect = 0.006
 Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 8/72 (11%)

Query: 36  EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEE--PGEPAGLGELGEPAGPGEPE 93
           EP R P    P   ++  P+P    + EPA     P    PG+PA      E  G   P 
Sbjct: 165 EPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPA------EVDGNPPPA 218

Query: 94  GPGDPAAAPAEA 105
            P  PAA+P+ A
Sbjct: 219 APEAPAASPSTA 230



 Score = 37.0 bits (84), Expect = 0.008
 Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 6/82 (7%)

Query: 28  RRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87
           +RG AASP    +   P+PPA  +  PA      P  A  P  P +P E  G      P 
Sbjct: 167 QRGPAASPPQEPSSRPPSPPAGLSTEPA-----GPGTAPRPFLPGQPAEVDGNPPPAAPE 221

Query: 88  GPGEPEGPGDPA-AAPAEAEEQ 108
            P        PA AAP +  ++
Sbjct: 222 APAASPSTASPAPAAPGDLRQE 243



 Score = 28.5 bits (62), Expect = 2.9
 Identities = 33/120 (27%), Positives = 41/120 (34%), Gaps = 35/120 (29%)

Query: 37  PARAPPEPAPPAEATGAPAPSRPC------------------APEPAASPAGPEEPGEPA 78
           PA     PA P  +  +P P +PC                    +P AS  GP  PGE A
Sbjct: 6   PAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGP-GPGELA 64

Query: 79  GLGE-LGEPAGPGEPEG---------------PGDPAAAPAEAEEQAVEARQEEEQDLDG 122
                L  P  P  P G               PG P  A  E  + A   R+ EE++  G
Sbjct: 65  ARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGG 124


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 46/142 (32%), Positives = 57/142 (40%), Gaps = 14/142 (9%)

Query: 3   APAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAE----ATGAPAPSR 58
           APA   A  PALA+A         V     ASP+  R+PPE A P E     T  PAP+R
Sbjct: 514 APAPAPAPAPALASAATKERTESEVPP-RPASPKVTRSPPETAAPVEDMARRTKRPAPAR 572

Query: 59  PCAPEP--AASPAGPEEPGEPAGLGELGEP-AGPGEPEGPG------DPAAAPAEAEEQA 109
           P  P P  + S + P  P  P G G  G P A P    G         P   P   +   
Sbjct: 573 PTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPAR 632

Query: 110 VEARQEEEQDLDGEKGPSSEGP 131
            ++R+          GP+S  P
Sbjct: 633 RQSRRSPASPSPASPGPASPSP 654



 Score = 32.3 bits (72), Expect = 0.20
 Identities = 25/78 (32%), Positives = 32/78 (41%), Gaps = 10/78 (12%)

Query: 32  AASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE 91
           A+   P+ A P PA     T APAP+   AP PA + A  +E  E         P  P  
Sbjct: 495 ASEELPSTAVPTPA----TTPAPAPAPAPAPAPALASAATKERTESE------VPPRPAS 544

Query: 92  PEGPGDPAAAPAEAEEQA 109
           P+    P    A  E+ A
Sbjct: 545 PKVTRSPPETAAPVEDMA 562



 Score = 32.0 bits (71), Expect = 0.26
 Identities = 23/81 (28%), Positives = 27/81 (33%), Gaps = 4/81 (4%)

Query: 26  LVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE 85
           LV     A   P   PP P  PA      +P+ P    P  +   P     PA +     
Sbjct: 609 LVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAA 668

Query: 86  PAGPGEPEG----PGDPAAAP 102
            A  G PE     P  PA  P
Sbjct: 669 TAEGGAPEAISGVPTPPAIPP 689



 Score = 29.3 bits (64), Expect = 1.7
 Identities = 26/100 (26%), Positives = 38/100 (38%), Gaps = 3/100 (3%)

Query: 12  PALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAA-SPAG 70
           P    AL   L    +R      P P   PP+PA   ++  +PA   P +P PA+ SP  
Sbjct: 599 PGTPQALPRRLVGSSLRAPTVPPPLPP-TPPQPA-RRQSRRSPASPSPASPGPASPSPVS 656

Query: 71  PEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAV 110
              P +        E   P    G   P A P +   +++
Sbjct: 657 LSNPAQVDLGAATAEGGAPEAISGVPTPPAIPPQPRPRSL 696


>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 39/129 (30%), Positives = 47/129 (36%), Gaps = 8/129 (6%)

Query: 35  PEPARAP---PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE 91
           P P  AP   P PAP A    AP      AP PA +PA    P   A       PA    
Sbjct: 139 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 198

Query: 92  PEGPGDPAAAPAEAEEQAVEARQEEEQDL-----DGEKGPSSEGPEEEDGEGFSFKYSPG 146
           P     P AAP E+ EQ     Q  ++ L      G  G  + G       G + K   G
Sbjct: 199 PAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSG 258

Query: 147 KLRGNQYKK 155
            L  + + K
Sbjct: 259 PLISDFFAK 267



 Score = 43.5 bits (101), Expect = 9e-05
 Identities = 42/110 (38%), Positives = 51/110 (46%), Gaps = 10/110 (9%)

Query: 4   PAELLAALPALATA-----LALLLAWLLVRRGAAASPEPARAPPEPAPPAEATG-APAPS 57
           P  +LA  PA A A     +A  +A  ++    A +P PA AP   A PA A   APAP+
Sbjct: 139 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 198

Query: 58  RPCAPEPAASPAGPEEPGEPAGLGELG-EPAGPGEPEG-PGDPAAAPAEA 105
              AP P A+P    E G  A  G+ G EP       G  G PAA  A A
Sbjct: 199 PAPAPAPDAAPQESAEQG--ANQGQRGQEPLADQLHSGISGRPAAGTAAA 246


>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 39/129 (30%), Positives = 47/129 (36%), Gaps = 8/129 (6%)

Query: 35  PEPARAP---PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE 91
           P P  AP   P PAP A    AP      AP PA +PA    P   A       PA    
Sbjct: 139 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 198

Query: 92  PEGPGDPAAAPAEAEEQAVEARQEEEQDL-----DGEKGPSSEGPEEEDGEGFSFKYSPG 146
           P     P AAP E+ EQ     Q  ++ L      G  G  + G       G + K   G
Sbjct: 199 PAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSG 258

Query: 147 KLRGNQYKK 155
            L  + + K
Sbjct: 259 PLISDFFAK 267



 Score = 43.5 bits (101), Expect = 9e-05
 Identities = 42/110 (38%), Positives = 51/110 (46%), Gaps = 10/110 (9%)

Query: 4   PAELLAALPALATA-----LALLLAWLLVRRGAAASPEPARAPPEPAPPAEATG-APAPS 57
           P  +LA  PA A A     +A  +A  ++    A +P PA AP   A PA A   APAP+
Sbjct: 139 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 198

Query: 58  RPCAPEPAASPAGPEEPGEPAGLGELG-EPAGPGEPEG-PGDPAAAPAEA 105
              AP P A+P    E G  A  G+ G EP       G  G PAA  A A
Sbjct: 199 PAPAPAPDAAPQESAEQG--ANQGQRGQEPLADQLHSGISGRPAAGTAAA 246


>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
           sapiens]
          Length = 316

 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 39/129 (30%), Positives = 47/129 (36%), Gaps = 8/129 (6%)

Query: 35  PEPARAP---PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE 91
           P P  AP   P PAP A    AP      AP PA +PA    P   A       PA    
Sbjct: 150 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 209

Query: 92  PEGPGDPAAAPAEAEEQAVEARQEEEQDL-----DGEKGPSSEGPEEEDGEGFSFKYSPG 146
           P     P AAP E+ EQ     Q  ++ L      G  G  + G       G + K   G
Sbjct: 210 PAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSG 269

Query: 147 KLRGNQYKK 155
            L  + + K
Sbjct: 270 PLISDFFAK 278



 Score = 43.5 bits (101), Expect = 9e-05
 Identities = 42/110 (38%), Positives = 51/110 (46%), Gaps = 10/110 (9%)

Query: 4   PAELLAALPALATA-----LALLLAWLLVRRGAAASPEPARAPPEPAPPAEATG-APAPS 57
           P  +LA  PA A A     +A  +A  ++    A +P PA AP   A PA A   APAP+
Sbjct: 150 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 209

Query: 58  RPCAPEPAASPAGPEEPGEPAGLGELG-EPAGPGEPEG-PGDPAAAPAEA 105
              AP P A+P    E G  A  G+ G EP       G  G PAA  A A
Sbjct: 210 PAPAPAPDAAPQESAEQG--ANQGQRGQEPLADQLHSGISGRPAAGTAAA 257


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 42/133 (31%), Positives = 50/133 (37%), Gaps = 26/133 (19%)

Query: 29   RGAAASPEPARAPPEPAPPAEA--------TGAPAPSRPCAPEPAASPAGPEEPGEPAGL 80
            RG    P P      P PP E          G P P  P  P  A    GP+ P  P G+
Sbjct: 1218 RGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGP--PGGI 1275

Query: 81   GELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-------EGPEE 133
            G  G     GEP   G+P   P E      +  + E+    GE GPS        +GP  
Sbjct: 1276 GNPGAVGEKGEPGEAGEP-GLPGEGGPPGPKGERGEK----GESGPSGAAGPPGPKGPPG 1330

Query: 134  EDGEGFSFKYSPG 146
            +DG     K SPG
Sbjct: 1331 DDGP----KGSPG 1339



 Score = 47.0 bits (110), Expect = 8e-06
 Identities = 40/122 (32%), Positives = 48/122 (39%), Gaps = 14/122 (11%)

Query: 30   GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89
            G   SP P   P +P PP E    P P+    P       G  EPG+    G  GEP   
Sbjct: 1333 GPKGSPGPVGFPGDPGPPGE----PGPAGQDGPPGDKGDDG--EPGQTGSPGPTGEPGPS 1386

Query: 90   GEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGEGFSFKYSPGKL 148
            G P   G P   PA  E +  E   + E  L+G  G +   GP+   G     K  P  L
Sbjct: 1387 GPPGKRGPP--GPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPG-----KPGPDGL 1439

Query: 149  RG 150
            RG
Sbjct: 1440 RG 1441



 Score = 44.7 bits (104), Expect = 4e-05
 Identities = 37/123 (30%), Positives = 43/123 (34%), Gaps = 16/123 (13%)

Query: 30   GAAASPEPARAPPEPAP-----PAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELG 84
            G    P PA +P E  P     P    G P P  P  P       G + P  PAG   L 
Sbjct: 1078 GPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQ 1137

Query: 85   EPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGP----------SSEGPEEE 134
             P G   P GP  P     +  E   E  Q+  +   GE+GP             GP   
Sbjct: 1138 GPVGLPGPAGPVGPPGEDGDKGEIG-EPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGA 1196

Query: 135  DGE 137
            DGE
Sbjct: 1197 DGE 1199



 Score = 44.3 bits (103), Expect = 5e-05
 Identities = 43/132 (32%), Positives = 49/132 (37%), Gaps = 18/132 (13%)

Query: 22   LAWLLVRRGAAASPEPARAPPEPAPPAEA-----TGAPAPSRPCAPEPAASPAGPE---- 72
            L  L  + G    P PA  P +  PP         G P P      +    P GP     
Sbjct: 1028 LPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAG 1087

Query: 73   EPGE--PAGL-GELGEPAGPGE--PEGPGDPAAAPAEAEEQAVEARQ--EEEQDLDGEKG 125
             PGE  PAG  G +G P  PG   P GP     AP E   Q    R   +    L G  G
Sbjct: 1088 SPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAG 1147

Query: 126  PSSEGPEEEDGE 137
            P   GP  EDG+
Sbjct: 1148 P--VGPPGEDGD 1157



 Score = 41.2 bits (95), Expect = 4e-04
 Identities = 37/136 (27%), Positives = 45/136 (33%), Gaps = 42/136 (30%)

Query: 30   GAAASPEPARAPPEPAPPAEA-----------------TGAPAPSRPCAPEPAASPAGPE 72
            G    P P+  P +  PP  A                  G P  + P  P+ A    GP+
Sbjct: 1378 GPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPD 1437

Query: 73   E-PGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-- 129
               G P  +GE G P  PG P+GP  P   P                 L G+ GP  E  
Sbjct: 1438 GLRGIPGPVGEQGLPGSPG-PDGPPGPMGPPG-------------LPGLKGDSGPKGEKG 1483

Query: 130  --------GPEEEDGE 137
                    GP  E GE
Sbjct: 1484 HPGLIGLIGPPGEQGE 1499



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 34/130 (26%), Positives = 50/130 (38%), Gaps = 16/130 (12%)

Query: 41   PPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAA 100
            P  P  P    G P P  P   + ++ P GP+        GE G P  PG P  PG+   
Sbjct: 1523 PSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPK--------GEAGHPGPPGPPGPPGE-VI 1573

Query: 101  APAEAEEQAVEARQEEEQDLDGEKGPS----SEGPEEEDGEGFSFKYSPGKLR---GNQY 153
             P   +        +  Q LD   G +    ++G EE  G   S K    +++   G Q 
Sbjct: 1574 QPLPIQASRTRRNIDASQLLDDGNGENYVDYADGMEEIFGSLNSLKLEIEQMKRPLGTQQ 1633

Query: 154  KKMMTKEELE 163
                T ++L+
Sbjct: 1634 NPARTCKDLQ 1643



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 36/113 (31%), Positives = 43/113 (38%), Gaps = 18/113 (15%)

Query: 36   EPARAPPEPAPPAEATGAPAPSRP------CAPEPAASPAGPEEP----GEPAGLGELGE 85
            EP  A  EP  P E  G P P           P  AA P GP+ P    G     G +G 
Sbjct: 1286 EPGEAG-EPGLPGEG-GPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGF 1343

Query: 86   PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGE 137
            P  PG P  PG     PA  +    +   + E    G  GP+ E GP    G+
Sbjct: 1344 PGDPGPPGEPG-----PAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGK 1391



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 32/103 (31%), Positives = 37/103 (35%), Gaps = 9/103 (8%)

Query: 35   PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG 94
            P     PP P       G P             P GP  P  P+G      P GP  P G
Sbjct: 1217 PRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGP--PGG 1274

Query: 95   PGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGE 137
             G+P A   +      E  +  E  L GE GP   GP+ E GE
Sbjct: 1275 IGNPGAVGEKG-----EPGEAGEPGLPGEGGP--PGPKGERGE 1310



 Score = 37.4 bits (85), Expect = 0.006
 Identities = 34/119 (28%), Positives = 41/119 (34%), Gaps = 17/119 (14%)

Query: 29  RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG 88
           RG      P   P EP P     G   P  P  P P   P      G+P   G +G    
Sbjct: 663 RGDDGEVGPRGLPGEPGP----RGLLGPKGP--PGPPGPPGVTGMDGQPGPKGNVGPQGE 716

Query: 89  PGEPEGPGDPAAAPAEAEEQAVEARQEE----EQDLDGEKG-------PSSEGPEEEDG 136
           PG P   G+P A      + A+    E+    +  L G  G       P  EGP  E G
Sbjct: 717 PGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKG 775



 Score = 37.4 bits (85), Expect = 0.006
 Identities = 33/116 (28%), Positives = 40/116 (34%), Gaps = 8/116 (6%)

Query: 29   RGAAASPEPA--RAPPEPAP---PAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGEL 83
            RG    P P   R P  P     P   TG P P      +  A P G   P  P G    
Sbjct: 900  RGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGF 959

Query: 84   GEPAGPGEPEGPGDPAAAPAEAEEQAVEAR--QEEEQDLDGEKGPSSE-GPEEEDG 136
              P GP  P G       P +  E   + +        + G +GP+ E GP  E G
Sbjct: 960  PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERG 1015



 Score = 36.6 bits (83), Expect = 0.011
 Identities = 34/124 (27%), Positives = 43/124 (34%), Gaps = 28/124 (22%)

Query: 28  RRGAAASPEPARAPPEPAPPAEA-----TGAPAPSRPCA-PEPAASPAGPEEPGEPAGLG 81
           RRG A S      P +  P  +       G P        P P+  P  P + GE    G
Sbjct: 608 RRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDG 667

Query: 82  ELGEPAGPGE--------PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-GPE 132
           E+G    PGE        P+GP  P   P                 +DG+ GP    GP+
Sbjct: 668 EVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVT-------------GMDGQPGPKGNVGPQ 714

Query: 133 EEDG 136
            E G
Sbjct: 715 GEPG 718



 Score = 36.6 bits (83), Expect = 0.011
 Identities = 25/76 (32%), Positives = 28/76 (36%), Gaps = 3/76 (3%)

Query: 29   RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG 88
            +G    P     P  P    E TG    + P  P     P GP   GE   +GE G P  
Sbjct: 963  KGPPGPPGKDGLPGHPGQRGE-TGFQGKTGPPGPPGVVGPQGPT--GETGPMGERGHPGP 1019

Query: 89   PGEPEGPGDPAAAPAE 104
            PG P   G P  A  E
Sbjct: 1020 PGPPGEQGLPGLAGKE 1035



 Score = 35.0 bits (79), Expect = 0.031
 Identities = 24/65 (36%), Positives = 25/65 (38%), Gaps = 9/65 (13%)

Query: 43  EPAPPAE-----ATGAPAPSRPCAPEPAASPAG-PEEPGEPAGLGELGEPAG---PGEPE 93
           EP PP +     A G P P     P     P G P  PG P   G  G P     PGE  
Sbjct: 716 EPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKG 775

Query: 94  GPGDP 98
           G G P
Sbjct: 776 GQGPP 780



 Score = 34.3 bits (77), Expect = 0.053
 Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 20/89 (22%)

Query: 36  EPARAPPE--PAPPA------EATGAPAPSRPCAPEPAA--------SPAGPEEP----G 75
           +P  +P E  P  PA      E  G P   +    EPA          P GPE P    G
Sbjct: 422 DPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPG 481

Query: 76  EPAGLGELGEPAGPGEPEGPGDPAAAPAE 104
            P  +G  G+   PGE   PG P    A+
Sbjct: 482 PPGTMGPTGQVGDPGERGPPGRPGLPGAD 510



 Score = 34.3 bits (77), Expect = 0.053
 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 20/110 (18%)

Query: 29   RGAAASPEP--ARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86
            +GA   P P   R  P P       G+P P  P  P P   P  P   G+    GE G P
Sbjct: 1428 QGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGP--PGPMGPPGLPGLKGDSGPKGEKGHP 1485

Query: 87   AGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG 136
               G    PG              E  ++ ++ L G +G  S GP+ E G
Sbjct: 1486 GLIGLIGPPG--------------EQGEKGDRGLPGPQG--SSGPKGEQG 1519



 Score = 33.9 bits (76), Expect = 0.069
 Identities = 25/86 (29%), Positives = 33/86 (38%), Gaps = 16/86 (18%)

Query: 44  PAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPA 103
           PA P   TG P P  P        P      GEP  +G    P GP   +GP  PA  P 
Sbjct: 560 PAGPMGLTGRPGPVGP--------PGSGGLKGEPGDVG----PQGPRGVQGPPGPAGKPG 607

Query: 104 EAEEQAVEARQEEEQDLDGEKGPSSE 129
               +   A  +  + + G+ GP  +
Sbjct: 608 ----RRGRAGSDGARGMPGQTGPKGD 629



 Score = 32.7 bits (73), Expect = 0.15
 Identities = 39/138 (28%), Positives = 46/138 (33%), Gaps = 24/138 (17%)

Query: 28  RRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87
           ++G  A  EP      P  P    G P P  P    P      P E G P   G  G   
Sbjct: 454 QKGEPAIIEPGMLIEGPPGPEGPAGLPGP--PGTMGPTGQVGDPGERGPPGRPGLPGADG 511

Query: 88  GPGEP----------EGPGD-----PAAAPAEAEEQAVEARQEEEQDLDGEKGP----SS 128
            PG P           G GD     P  +  E++ QA+   Q+    L G  GP      
Sbjct: 512 LPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAI--LQQARLALRGPAGPMGLTGR 569

Query: 129 EGPEEEDGEGFSFKYSPG 146
            GP    G G   K  PG
Sbjct: 570 PGPVGPPGSG-GLKGEPG 586



 Score = 32.7 bits (73), Expect = 0.15
 Identities = 34/119 (28%), Positives = 42/119 (35%), Gaps = 16/119 (13%)

Query: 30  GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89
           GA   P P  A     PP E      P  P  P     P  P + G P   G  G P GP
Sbjct: 727 GAQGLPGPQGAI---GPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQG-PPGP 782

Query: 90  GEPEG-PGDPAAAPAEAEEQAVEARQEEEQD----------LDGEKGP-SSEGPEEEDG 136
             P G PG      A+        + E+ +D          + G++G     GP  EDG
Sbjct: 783 QGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDG 841



 Score = 32.3 bits (72), Expect = 0.20
 Identities = 35/124 (28%), Positives = 41/124 (33%), Gaps = 10/124 (8%)

Query: 17  ALALLLAWLLVRRGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEP 74
           A A+L    L  RG A        P    PP      G P    P  P     P GP   
Sbjct: 546 AQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPA-- 603

Query: 75  GEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEE 133
           G+P   G  G     G P   G       +       A    E+   G+ GPS   GP  
Sbjct: 604 GKPGRRGRAGSDGARGMPGQTGPKGDRGFDG-----LAGLPGEKGHRGDPGPSGPPGPPG 658

Query: 134 EDGE 137
           +DGE
Sbjct: 659 DDGE 662



 Score = 30.4 bits (67), Expect = 0.77
 Identities = 20/65 (30%), Positives = 22/65 (33%), Gaps = 5/65 (7%)

Query: 46   PPAEA-----TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAA 100
            PP E       G P P     P+      GP  P  P G   L  P GP   +G   P  
Sbjct: 1493 PPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTG 1552

Query: 101  APAEA 105
               EA
Sbjct: 1553 PKGEA 1557



 Score = 30.0 bits (66), Expect = 1.0
 Identities = 20/57 (35%), Positives = 23/57 (40%), Gaps = 6/57 (10%)

Query: 30   GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86
            G    P P   P  P P     GA   S P  P+  A   GP  PG P   GE+ +P
Sbjct: 1525 GPIGPPGPPGLPGPPGPK----GAKGSSGPTGPKGEAGHPGP--PGPPGPPGEVIQP 1575



 Score = 29.3 bits (64), Expect = 1.7
 Identities = 18/47 (38%), Positives = 19/47 (40%), Gaps = 2/47 (4%)

Query: 52  GAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDP 98
           G P P     PE      GP   G+P  LG  GE    G P  PG P
Sbjct: 832 GPPGPRGEDGPEGPKGRGGPN--GDPGPLGPPGEKGKLGVPGLPGYP 876


>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
          Length = 686

 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 43/117 (36%), Positives = 51/117 (43%), Gaps = 17/117 (14%)

Query: 29  RGAAASPEPARAPPEPAPPAEATG-----APAPSRPCAPEPAASPAGPEE-------PGE 76
           RGAAA  E     P+  P AEA G         +   APE A  P G EE        G 
Sbjct: 52  RGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGA 111

Query: 77  PAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPS--SEGP 131
             G G  GEP G  + E P D AA   E +E+A +  +  E    GE G S  +EGP
Sbjct: 112 SPGRGAQGEPRGEAQRE-PEDSAA--PERQEEAEQRPEVPEGSASGEAGDSVDAEGP 165



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 37/139 (26%), Positives = 54/139 (38%), Gaps = 8/139 (5%)

Query: 34  SPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPE 93
           +P P   P  PAP AE  G P  +   A  P  S    E P   A + E G   G G   
Sbjct: 11  APGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAG---GGGPDR 67

Query: 94  GPGDPAAAP--AEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKLRGN 151
           GP   A     A  E +A E   E  +   G  G  + G ++ +G     + + G+ RG 
Sbjct: 68  GPEAEARGTRGAHGETEAEEGAPEGAEVPQG--GEETSGAQQVEGAS-PGRGAQGEPRGE 124

Query: 152 QYKKMMTKEELEEEQRTEE 170
             ++       E ++  E+
Sbjct: 125 AQREPEDSAAPERQEEAEQ 143



 Score = 36.6 bits (83), Expect = 0.011
 Identities = 33/118 (27%), Positives = 43/118 (36%), Gaps = 9/118 (7%)

Query: 27  VRRGAAASPEPARAPPEPAPPAEATG-------APAPSRPCAPEPAASPAGPEEPGEPAG 79
           V  G +A   P     + A  AE  G       AP  +R  A E        +EPGE   
Sbjct: 313 VAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEE 372

Query: 80  LGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGE 137
             E   P GP E E  G    +P ++      +R   E +       + EGP E  GE
Sbjct: 373 RRE-RSPEGPREEEAAGGEEESP-DSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGE 428



 Score = 35.8 bits (81), Expect = 0.018
 Identities = 39/124 (31%), Positives = 48/124 (38%), Gaps = 22/124 (17%)

Query: 37  PARAPPEPAPPA----EATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG--PG 90
           PA    E   PA    +A G    +R  + EP  S  G   P   A     GE AG  PG
Sbjct: 265 PAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPG 324

Query: 91  E-----------PEGPGDPAAAPAEAEEQAVEAR-----QEEEQDLDGEKGPSSEGPEEE 134
           E           P   G   AAP +A   A E R     Q+E  + +  +  S EGP EE
Sbjct: 325 ELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREE 384

Query: 135 DGEG 138
           +  G
Sbjct: 385 EAAG 388



 Score = 34.7 bits (78), Expect = 0.041
 Identities = 33/101 (32%), Positives = 41/101 (40%), Gaps = 23/101 (22%)

Query: 65  AASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPA--------------EAEEQAV 110
           A  PAG     E    G +G+    G+P G G  A  PA              +AE  A 
Sbjct: 232 AEGPAGDSVDAE----GRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAG 287

Query: 111 EARQ---EEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKL 148
            AR+   E +Q  DG   P +E  E   GE  S   SPG+L
Sbjct: 288 RARRVSGEPQQSGDGSLSPQAEAIEVAAGE--SAGRSPGEL 326



 Score = 33.1 bits (74), Expect = 0.12
 Identities = 31/95 (32%), Positives = 39/95 (41%), Gaps = 9/95 (9%)

Query: 45  APPAEATGAPAPSRPCAPEPAASPAGPEE----PGEPAG--LGELGEPAGPGEPEGPGDP 98
           +P   A G P       PE +A+P   EE    P  P G   GE G+      P G    
Sbjct: 112 SPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIE 171

Query: 99  AAAPAEAEEQAVEARQEEEQDLDGEKGPS--SEGP 131
           A  PA    +A E R  +  D +G  G S  +EGP
Sbjct: 172 AEGPAGDSVEA-EGRVGDSVDAEGPAGDSVDAEGP 205


>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
          Length = 1295

 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 4/97 (4%)

Query: 37   PARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPG 96
            P+RAP     P  A  +P  ++P  P P   PA P EP  P     +  P  P  P+ P 
Sbjct: 1068 PSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPP 1127

Query: 97   DPAA----APAEAEEQAVEARQEEEQDLDGEKGPSSE 129
             P+     AP   E  A ++     +D  G   PS +
Sbjct: 1128 PPSGARSPAPTRKEFGAPKSPGTTRKDNIGRSQPSPQ 1164



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 36/127 (28%), Positives = 45/127 (35%), Gaps = 12/127 (9%)

Query: 33   ASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPA-------GPEEPG----EPAGLG 81
            A P   + PP P P A  T    P RP  P  A SPA        P+ PG    +  G  
Sbjct: 1100 AQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGAPKSPGTTRKDNIGRS 1159

Query: 82   ELGEPAGPGEPEGPGDPAAAPA-EAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFS 140
            +    AG   P   G   A P        + A Q   +   G   P S+    E  +G +
Sbjct: 1160 QPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGST 1219

Query: 141  FKYSPGK 147
            F   P K
Sbjct: 1220 FLPEPLK 1226


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.302    0.127    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,542,534
Number of Sequences: 37866
Number of extensions: 876993
Number of successful extensions: 31105
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1516
Number of HSP's successfully gapped in prelim test: 1825
Number of HSP's that attempted gapping in prelim test: 7570
Number of HSP's gapped (non-prelim): 13503
length of query: 170
length of database: 18,247,518
effective HSP length: 95
effective length of query: 75
effective length of database: 14,650,248
effective search space: 1098768600
effective search space used: 1098768600
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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