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Search of human proteins with 134284359
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens]
(392 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens] 819 0.0
gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens] 734 0.0
gi|50083287 LIM homeobox 8 [Homo sapiens] 402 e-112
gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens] 177 1e-44
gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens] 177 1e-44
gi|30795196 LIM homeobox protein 2 [Homo sapiens] 175 7e-44
gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens] 163 2e-40
gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens] 163 3e-40
gi|30410785 LIM homeobox protein 1 [Homo sapiens] 159 5e-39
gi|28893581 LIM homeobox transcription factor 1, alpha isoform a... 158 7e-39
gi|115387114 islet-1 [Homo sapiens] 158 9e-39
gi|21956641 ISL LIM homeobox 2 [Homo sapiens] 158 9e-39
gi|11641283 LIM homeobox protein 5 [Homo sapiens] 157 2e-38
gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens] 156 3e-38
gi|15375314 LIM homeobox protein 4 [Homo sapiens] 155 8e-38
gi|5803072 LIM domain only 4 [Homo sapiens] 107 1e-23
gi|4505005 LIM domain only 1 [Homo sapiens] 102 6e-22
gi|21361802 LIM domain only 3 [Homo sapiens] 98 1e-20
gi|47778935 LIM domain only 3 [Homo sapiens] 98 1e-20
gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens] 89 7e-18
gi|4505001 LIM domain kinase 1 [Homo sapiens] 84 3e-16
gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens] 80 2e-15
gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens] 80 2e-15
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] 75 8e-14
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens] 75 8e-14
gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens] 75 8e-14
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 74 3e-13
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 74 3e-13
gi|7662330 actin binding LIM protein family, member 3 [Homo sapi... 70 3e-12
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 70 3e-12
>gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens]
Length = 392
Score = 819 bits (2116), Expect = 0.0
Identities = 392/392 (100%), Positives = 392/392 (100%)
Query: 1 MYWKHENAAPALPEGCRLPAEGGPATDQVMAQPGSGCKATTRCLEGTAPPAMAQSDAEAL 60
MYWKHENAAPALPEGCRLPAEGGPATDQVMAQPGSGCKATTRCLEGTAPPAMAQSDAEAL
Sbjct: 1 MYWKHENAAPALPEGCRLPAEGGPATDQVMAQPGSGCKATTRCLEGTAPPAMAQSDAEAL 60
Query: 61 AGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWH 120
AGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWH
Sbjct: 61 AGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWH 120
Query: 121 VRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNA 180
VRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNA
Sbjct: 121 VRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNA 180
Query: 181 YHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSE 240
YHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSE
Sbjct: 181 YHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSE 240
Query: 241 QDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCR 300
QDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCR
Sbjct: 241 QDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCR 300
Query: 301 ARHKKHTPQHPVPPSGAPPSRLPSALSDDIHYTPFSSPERARMVTLHGYIESQVQCGQVH 360
ARHKKHTPQHPVPPSGAPPSRLPSALSDDIHYTPFSSPERARMVTLHGYIESQVQCGQVH
Sbjct: 301 ARHKKHTPQHPVPPSGAPPSRLPSALSDDIHYTPFSSPERARMVTLHGYIESQVQCGQVH 360
Query: 361 CRLPYTAPPVHLKADMDGPLSNRGEKVILFQY 392
CRLPYTAPPVHLKADMDGPLSNRGEKVILFQY
Sbjct: 361 CRLPYTAPPVHLKADMDGPLSNRGEKVILFQY 392
>gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens]
Length = 377
Score = 734 bits (1895), Expect = 0.0
Identities = 352/352 (100%), Positives = 352/352 (100%)
Query: 1 MYWKHENAAPALPEGCRLPAEGGPATDQVMAQPGSGCKATTRCLEGTAPPAMAQSDAEAL 60
MYWKHENAAPALPEGCRLPAEGGPATDQVMAQPGSGCKATTRCLEGTAPPAMAQSDAEAL
Sbjct: 1 MYWKHENAAPALPEGCRLPAEGGPATDQVMAQPGSGCKATTRCLEGTAPPAMAQSDAEAL 60
Query: 61 AGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWH 120
AGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWH
Sbjct: 61 AGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWH 120
Query: 121 VRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNA 180
VRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNA
Sbjct: 121 VRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNA 180
Query: 181 YHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSE 240
YHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSE
Sbjct: 181 YHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSE 240
Query: 241 QDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCR 300
QDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCR
Sbjct: 241 QDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCR 300
Query: 301 ARHKKHTPQHPVPPSGAPPSRLPSALSDDIHYTPFSSPERARMVTLHGYIES 352
ARHKKHTPQHPVPPSGAPPSRLPSALSDDIHYTPFSSPERARMVTLHGYIES
Sbjct: 301 ARHKKHTPQHPVPPSGAPPSRLPSALSDDIHYTPFSSPERARMVTLHGYIES 352
>gi|50083287 LIM homeobox 8 [Homo sapiens]
Length = 356
Score = 402 bits (1032), Expect = e-112
Identities = 195/320 (60%), Positives = 241/320 (75%), Gaps = 6/320 (1%)
Query: 37 CKATTRCLEGTAPPAMAQSDAEALAGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGK 96
C TT G + + GA D+D +S P +PS A+ S GK
Sbjct: 15 CGRTTALAAGRTRKGAGEEGLVSPEGAGDEDSCSSS--APLSPSSSPRSMASGSGCPPGK 72
Query: 97 NICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRF 156
+C+SCGLEI+D+YLLKVN+L WHVRCL CSVCRTSL + SCYIK+K+IFCK+DYF R+
Sbjct: 73 CVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRY 132
Query: 157 GTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDT 216
GT+C+RCGR I+++DWVRRA+GN YHLACFACFSCKRQLSTGEEF LVEEKVLCR+HYD
Sbjct: 133 GTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHYDC 192
Query: 217 MIENLKRAAENGNGLTLEGAVPSEQD-SQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDA 275
M++NLKR ENGNG+++EGA+ +EQD + PKPAKRARTSFTA+QLQVMQAQFAQDNNPDA
Sbjct: 193 MLDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDA 252
Query: 276 QTLQKLADMTGLSRRVIQVWFQNCRARHKKH-TPQH--PVPPSGAPPSRLPSALSDDIHY 332
QTLQKLA+ TGLSRRVIQVWFQNCRARHKKH +P H P + PPSRL + +++ Y
Sbjct: 253 QTLQKLAERTGLSRRVIQVWFQNCRARHKKHVSPNHSSSTPVTAVPPSRLSPPMLEEMAY 312
Query: 333 TPFSSPERARMVTLHGYIES 352
+ + + + LH Y+++
Sbjct: 313 SAYVPQDGTMLTALHSYMDA 332
>gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens]
Length = 397
Score = 177 bits (450), Expect = 1e-44
Identities = 95/256 (37%), Positives = 144/256 (56%), Gaps = 47/256 (18%)
Query: 98 ICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFG 157
+C+ CG +I DRY L + WH+RCL+C C+ +L + +C+ K+ I+CK DY+ RF
Sbjct: 70 LCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFS 129
Query: 158 T-KCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDT 216
+CARC I AS+ V RAR + YHL+CF C +C + L+TG+ FG+ + V CR H++T
Sbjct: 130 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFET 189
Query: 217 MIEN--------LKRAAE---------NGNGLTLEG------------------------ 235
+++ + AA+ NG G +G
Sbjct: 190 LLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNEN 249
Query: 236 -AVPSEQDSQPKP----AKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRR 290
A ++D QP P KR RTSF QL+ M++ FA ++NPDA+ L++LA TGL++R
Sbjct: 250 EADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKR 309
Query: 291 VIQVWFQNCRARHKKH 306
V+QVWFQN RA+ +++
Sbjct: 310 VLQVWFQNARAKFRRN 325
>gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens]
Length = 388
Score = 177 bits (450), Expect = 1e-44
Identities = 95/256 (37%), Positives = 144/256 (56%), Gaps = 47/256 (18%)
Query: 98 ICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFG 157
+C+ CG +I DRY L + WH+RCL+C C+ +L + +C+ K+ I+CK DY+ RF
Sbjct: 61 LCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFS 120
Query: 158 T-KCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDT 216
+CARC I AS+ V RAR + YHL+CF C +C + L+TG+ FG+ + V CR H++T
Sbjct: 121 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFET 180
Query: 217 MIEN--------LKRAAE---------NGNGLTLEG------------------------ 235
+++ + AA+ NG G +G
Sbjct: 181 LLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNEN 240
Query: 236 -AVPSEQDSQPKP----AKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRR 290
A ++D QP P KR RTSF QL+ M++ FA ++NPDA+ L++LA TGL++R
Sbjct: 241 EADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKR 300
Query: 291 VIQVWFQNCRARHKKH 306
V+QVWFQN RA+ +++
Sbjct: 301 VLQVWFQNARAKFRRN 316
>gi|30795196 LIM homeobox protein 2 [Homo sapiens]
Length = 406
Score = 175 bits (443), Expect = 7e-44
Identities = 105/318 (33%), Positives = 162/318 (50%), Gaps = 79/318 (24%)
Query: 53 AQSDAEALAGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLL 112
A+S+A A++ A+D+ + + + PS+ S +A +C+ CG +I DRY L
Sbjct: 22 AKSEAPAISSAIDRGDTETT-----MPSISSDRAA----------LCAGCGGKISDRYYL 66
Query: 113 KVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGT-KCARCGRQIYASD 171
+ WH+RCL+C C+ +L + +C+ K+ I+CK DY+ RF +CARC I AS+
Sbjct: 67 LAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHLGISASE 126
Query: 172 WVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIEN----------- 220
V RAR YHL CF C +C + L+TG+ FG+ + V CR+H++ +++
Sbjct: 127 MVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEALLQGEYPAHFNHADV 186
Query: 221 ----LKRAAENGNGLTLEGAVP-------------------------------------- 238
AA GL GA P
Sbjct: 187 AAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQKGRPRKRKSPGPGADLAAYNAALSC 246
Query: 239 SEQDS------QPKPA----KRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLS 288
+E D+ QP P+ KR RTSF QL+ M++ FA ++NPDA+ L++LA TGL+
Sbjct: 247 NENDAEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLT 306
Query: 289 RRVIQVWFQNCRARHKKH 306
+RV+QVWFQN RA+ +++
Sbjct: 307 KRVLQVWFQNARAKFRRN 324
>gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]
Length = 397
Score = 163 bits (413), Expect = 2e-40
Identities = 86/225 (38%), Positives = 128/225 (56%), Gaps = 28/225 (12%)
Query: 85 PSAASSVPSAGKN---ICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYI 141
P AA+ G +C+ C ILDR++LK + WH +CL+CS C T L ++ C+
Sbjct: 14 PGAAAVCTLGGTREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFS 71
Query: 142 KNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEF 201
+ + ++CK D+F RFGTKCA C I + VRRA+ YHL CFAC CKRQL+TG+EF
Sbjct: 72 RGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEF 131
Query: 202 GLVEE-KVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQL 260
L+E+ +++C+ Y+T ++Q AKR RT+ TA+QL
Sbjct: 132 YLMEDSRLVCKADYET----------------------AKQREAEATAKRPRTTITAKQL 169
Query: 261 QVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKK 305
+ +++ + P ++L+ TGL RV+QVWFQN RA+ K+
Sbjct: 170 ETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKR 214
>gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]
Length = 402
Score = 163 bits (412), Expect = 3e-40
Identities = 82/209 (39%), Positives = 123/209 (58%), Gaps = 25/209 (11%)
Query: 98 ICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFG 157
+C+ C ILDR++LK + WH +CL+CS C T L ++ C+ + + ++CK D+F RFG
Sbjct: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFSRGESVYCKDDFFKRFG 92
Query: 158 TKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEE-KVLCRIHYDT 216
TKCA C I + VRRA+ YHL CFAC CKRQL+TG+EF L+E+ +++C+ Y+T
Sbjct: 93 TKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYET 152
Query: 217 MIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQ 276
++Q AKR RT+ TA+QL+ +++ + P
Sbjct: 153 ----------------------AKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARH 190
Query: 277 TLQKLADMTGLSRRVIQVWFQNCRARHKK 305
++L+ TGL RV+QVWFQN RA+ K+
Sbjct: 191 VREQLSSETGLDMRVVQVWFQNRRAKEKR 219
>gi|30410785 LIM homeobox protein 1 [Homo sapiens]
Length = 406
Score = 159 bits (401), Expect = 5e-39
Identities = 90/239 (37%), Positives = 128/239 (53%), Gaps = 37/239 (15%)
Query: 99 CSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGT 158
C+ C ILDR+LL V + WHV+C++C C+ +L ++ C+ + +++CK D+F FGT
Sbjct: 4 CAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEK--CFSREGKLYCKNDFFRCFGT 61
Query: 159 KCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEE-KVLCRIHYDTM 217
KCA C + I SD VRRAR +HL CF C C +QLSTGEE +++E K +C+ Y
Sbjct: 62 KCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDY--- 118
Query: 218 IENLKRAAENGNGLTLEGAVPS-----------------------------EQDSQPKPA 248
+ N A EN G+ PS E D Q A
Sbjct: 119 LSNSSVAKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEAGSNENDDQNLGA 178
Query: 249 KR--ARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKK 305
KR RT+ A+QL+ ++A FA P ++LA TGL+ RVIQVWFQN R++ ++
Sbjct: 179 KRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERR 237
>gi|28893581 LIM homeobox transcription factor 1, alpha isoform a
[Homo sapiens]
Length = 382
Score = 158 bits (400), Expect = 7e-39
Identities = 104/321 (32%), Positives = 160/321 (49%), Gaps = 33/321 (10%)
Query: 96 KNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSR 155
K++C C ILDR+LL++N+ WH +C++C+ C+ L + +C+ ++K+++CK DY
Sbjct: 32 KSVCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPL--ETTCFYRDKKLYCKYDYEKL 89
Query: 156 FGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYD 215
F KC C I +++V RA+ + YHL+CF C C+RQL G+EF L E ++LC+ Y+
Sbjct: 90 FAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYE 149
Query: 216 TMIENLK----RAAENGNGLTLE---------GAVPSEQDSQPKPAKRARTSFTAEQLQV 262
E L A+++G E G +E+ K KR RT T +Q +
Sbjct: 150 KERELLSLVSPAASDSGKSDDEESLCKSAHGAGKGTAEEGKDHKRPKRPRTILTTQQRRA 209
Query: 263 MQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKK---------HTPQHPVP 313
+A F + P + + LA TGLS RV+QVWFQN RA+ KK Q+
Sbjct: 210 FKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQQNTQR 269
Query: 314 PSGAPPSRLPSALSDDI--HYTPFSSPERARMVTLHGYIESQVQCGQVHCRL------PY 365
S A + SA + I YT +P++ + Y + G ++ PY
Sbjct: 270 LSSAQTNGGGSAGMEGIMNPYTALPTPQQLLAIEQSVYSSDPFRQGLTPPQMPGDHMHPY 329
Query: 366 TAPPVHLKADMDG-PLSNRGE 385
A P+ D D LSN G+
Sbjct: 330 GAEPLFHDLDSDDTSLSNLGD 350
>gi|115387114 islet-1 [Homo sapiens]
Length = 349
Score = 158 bits (399), Expect = 9e-39
Identities = 81/228 (35%), Positives = 126/228 (55%), Gaps = 19/228 (8%)
Query: 97 NICSSCGLEILDRYLLKVN-NLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSR 155
++C CG +I D+Y+L+V+ +L WH CL+C+ C L + +C++++ + +CK DY
Sbjct: 15 SLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRL 74
Query: 156 FGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYD 215
+G KCA+C +D+V RAR YH+ CF C +C RQL G+EF L E+ + CR +D
Sbjct: 75 YGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHD 134
Query: 216 TM----------------IENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQ 259
+ L+ AAE + + A+ QP+ R RT +Q
Sbjct: 135 VVERASLGAGDPLSPLHPARPLQMAAEPIS--ARQPALRPHVHKQPEKTTRVRTVLNEKQ 192
Query: 260 LQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHT 307
L ++ +A + PDA ++L +MTGLS RVI+VWFQN R + KK +
Sbjct: 193 LHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRS 240
>gi|21956641 ISL LIM homeobox 2 [Homo sapiens]
Length = 359
Score = 158 bits (399), Expect = 9e-39
Identities = 83/226 (36%), Positives = 124/226 (54%), Gaps = 15/226 (6%)
Query: 95 GKNICSSCGLEILDRYLLKVN-NLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYF 153
G +C CG +I D+++L+V+ +L WH CL+C+ C L + +C++++ + +CK DY
Sbjct: 23 GTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYV 82
Query: 154 SRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIH 213
FG KCA+C +SD V RAR + YH+ CF C C RQL G+EF L E ++LCR
Sbjct: 83 RLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRAD 142
Query: 214 YDTMIENLKRAA-------ENGNGLTLEGAVPSEQDS-------QPKPAKRARTSFTAEQ 259
+ ++E + GL L A Q + Q + R RT +Q
Sbjct: 143 HGLLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPALRPHVHKQTEKTTRVRTVLNEKQ 202
Query: 260 LQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKK 305
L ++ +A + PDA ++L +MTGLS RVI+VWFQN R + KK
Sbjct: 203 LHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 248
>gi|11641283 LIM homeobox protein 5 [Homo sapiens]
Length = 402
Score = 157 bits (396), Expect = 2e-38
Identities = 83/235 (35%), Positives = 129/235 (54%), Gaps = 30/235 (12%)
Query: 99 CSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGT 158
C+ C ILDR+LL V + WH++C++C C+T+L ++ C+ + +++CK D+F RFGT
Sbjct: 5 CAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEK--CFSREGKLYCKNDFFRRFGT 62
Query: 159 KCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEE-KVLCRIHY--- 214
KCA C + I SD VR+AR +HL CF C C +QLSTGEE +++E K +C+ Y
Sbjct: 63 KCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYLSS 122
Query: 215 ----DTMIENLKRAAENGNGLTLEGAV---PSEQDSQPKPAKRA---------------- 251
+ + ++ + L+ A+ P E D+ K
Sbjct: 123 SSLKEGSLNSVSSCTDRSLSPDLQDALQDDPKETDNSTSSDKETANNENEEQNSGTKRRG 182
Query: 252 -RTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKK 305
RT+ A+QL+ ++A FA P ++LA TGL+ RVIQVWFQN R++ ++
Sbjct: 183 PRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERR 237
>gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens]
Length = 372
Score = 156 bits (394), Expect = 3e-38
Identities = 90/265 (33%), Positives = 136/265 (51%), Gaps = 24/265 (9%)
Query: 98 ICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFG 157
+C C I DR+L++VN WH CL+C+ C+ +L SCY ++++++CK DY F
Sbjct: 32 VCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALT--TSCYFRDRKLYCKQDYQQLFA 89
Query: 158 TKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYD-- 215
KC+ C +I +++V RA YHL CF C C+RQL G+EF L E ++LC+ Y+
Sbjct: 90 AKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKE 149
Query: 216 ---------TMIENLKRAAENGNGLTLEGAVPSEQDS-----QPKPAKRARTSFTAEQLQ 261
+++K E+G+ +G + S P+ KR RT T +Q +
Sbjct: 150 KDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRR 209
Query: 262 VMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPSR 321
+A F + P + + LA TGLS RV+QVWFQN RA+ KK +H R
Sbjct: 210 AFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQR 269
Query: 322 L-PSALSDDIH-----YTPFSSPER 340
L LS + YTP + P++
Sbjct: 270 LGQEVLSSRMEGMMASYTPLAPPQQ 294
>gi|15375314 LIM homeobox protein 4 [Homo sapiens]
Length = 390
Score = 155 bits (391), Expect = 8e-38
Identities = 78/208 (37%), Positives = 118/208 (56%), Gaps = 24/208 (11%)
Query: 99 CSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGT 158
C+ C ILD+++LKV + WH CL+C+ C+ L + C+ + ++CK D+F RFGT
Sbjct: 30 CAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADR--CFSRAGSVYCKEDFFKRFGT 87
Query: 159 KCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEE-KVLCRIHYDTM 217
KC C + I + VR+A+ YHL CFAC C RQL+TG+EF L+E+ +++C+ Y+T
Sbjct: 88 KCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETA 147
Query: 218 IENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQT 277
+N D AKR RT+ TA+QL+ ++ + P
Sbjct: 148 KQN---------------------DDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHV 186
Query: 278 LQKLADMTGLSRRVIQVWFQNCRARHKK 305
++L+ TGL RV+QVWFQN RA+ K+
Sbjct: 187 REQLSSETGLDMRVVQVWFQNRRAKEKR 214
>gi|5803072 LIM domain only 4 [Homo sapiens]
Length = 165
Score = 107 bits (268), Expect = 1e-23
Identities = 55/140 (39%), Positives = 75/140 (53%), Gaps = 6/140 (4%)
Query: 84 PPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQ-QNSCYIK 142
PP A S+ C+ CG +I DR+LL + WH RCL+CS C+ L SCY K
Sbjct: 11 PPVTAGSL---SWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDIGTSCYTK 67
Query: 143 NKEIFCKMDYFSRFGTK--CARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEE 200
+ I C+ DY FG C+ CG+ I AS+ V RA+GN YHL CF C +C+ +L G+
Sbjct: 68 SGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRNRLVPGDR 127
Query: 201 FGLVEEKVLCRIHYDTMIEN 220
F + + C T + N
Sbjct: 128 FHYINGSLFCEHDRPTALIN 147
>gi|4505005 LIM domain only 1 [Homo sapiens]
Length = 156
Score = 102 bits (254), Expect = 6e-22
Identities = 51/127 (40%), Positives = 69/127 (54%), Gaps = 3/127 (2%)
Query: 92 PSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSC-YIKNKEIFCKM 150
P + C+ C +I DRYLLK + WH CL+C+ C L + S Y K I C+
Sbjct: 17 PKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRR 76
Query: 151 DYFSRFGT--KCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKV 208
DY FGT CA C + I A + V RAR N YHL CFAC C ++ G++F L +
Sbjct: 77 DYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMI 136
Query: 209 LCRIHYD 215
LC++ Y+
Sbjct: 137 LCQMDYE 143
>gi|21361802 LIM domain only 3 [Homo sapiens]
Length = 145
Score = 97.8 bits (242), Expect = 1e-20
Identities = 48/120 (40%), Positives = 65/120 (54%), Gaps = 3/120 (2%)
Query: 99 CSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSC-YIKNKEIFCKMDYFSRFG 157
C+ C +I DRYLLK + WH CL+C+ C L + S Y K I C+ DY FG
Sbjct: 13 CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFG 72
Query: 158 T--KCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYD 215
CA C + I A + V RA+ N YHL CFAC C ++ G++F L +LC+ Y+
Sbjct: 73 VTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDYE 132
>gi|47778935 LIM domain only 3 [Homo sapiens]
Length = 145
Score = 97.8 bits (242), Expect = 1e-20
Identities = 48/120 (40%), Positives = 65/120 (54%), Gaps = 3/120 (2%)
Query: 99 CSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSC-YIKNKEIFCKMDYFSRFG 157
C+ C +I DRYLLK + WH CL+C+ C L + S Y K I C+ DY FG
Sbjct: 13 CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFG 72
Query: 158 T--KCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYD 215
CA C + I A + V RA+ N YHL CFAC C ++ G++F L +LC+ Y+
Sbjct: 73 VTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDYE 132
>gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens]
Length = 227
Score = 89.0 bits (219), Expect = 7e-18
Identities = 58/201 (28%), Positives = 79/201 (39%), Gaps = 31/201 (15%)
Query: 13 PEGCRLPAEGGPATDQVMAQPGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDEGQAS 72
PEG R PA G P + P GT PP+ S E + LD E
Sbjct: 41 PEGVRAPAAGQPRATKGAPPP-----------PGTPPPSPMSSAIERKS--LDPSEEPVD 87
Query: 73 PCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTS 132
PS+ + C C I DRY LK + WH CL C +C
Sbjct: 88 EVLQIPPSLLT---------------CGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCR 132
Query: 133 LRQQNS-CYIKNKEIFCKMDYFSRFGTK--CARCGRQIYASDWVRRARGNAYHLACFACF 189
L + Y K C+ DY FG CA C ++I A + R + YHL CF C
Sbjct: 133 LGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCA 192
Query: 190 SCKRQLSTGEEFGLVEEKVLC 210
+C++ G+ + L+ ++C
Sbjct: 193 ACQKHFCVGDRYLLINSDIVC 213
Score = 33.5 bits (75), Expect = 0.34
Identities = 13/57 (22%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 98 ICSSCGLEILDRYL-LKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYF 153
+C+SC I + ++V + ++H+ C +C+ C+ + + N +I C+ D +
Sbjct: 162 LCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQDIY 218
>gi|4505001 LIM domain kinase 1 [Homo sapiens]
Length = 647
Score = 83.6 bits (205), Expect = 3e-16
Identities = 45/123 (36%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Query: 98 ICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFG 157
+C+SCG I D L+ N WH C C C SL Q Y K+ ++FCK DY++R+G
Sbjct: 24 VCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQ--YYEKDGQLFCKKDYWARYG 81
Query: 158 TKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVE-EKVLC-RIHYD 215
C C QI V A YH CF C +C + G+ + LVE K+ C +Y
Sbjct: 82 ESCHGCSEQI-TKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYCGHCYYQ 140
Query: 216 TMI 218
T++
Sbjct: 141 TVV 143
>gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens]
Length = 158
Score = 80.5 bits (197), Expect = 2e-15
Identities = 38/115 (33%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 99 CSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNS-CYIKNKEIFCKMDYFSRFG 157
C C I DRY LK + WH CL C +C L + Y K C+ DY FG
Sbjct: 30 CGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFG 89
Query: 158 TK--CARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLC 210
CA C ++I A + R + YHL CF C +C++ G+ + L+ ++C
Sbjct: 90 QDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVC 144
Score = 33.5 bits (75), Expect = 0.34
Identities = 13/57 (22%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 98 ICSSCGLEILDRYL-LKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYF 153
+C+SC I + ++V + ++H+ C +C+ C+ + + N +I C+ D +
Sbjct: 93 LCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQDIY 149
>gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens]
Length = 158
Score = 80.5 bits (197), Expect = 2e-15
Identities = 38/115 (33%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 99 CSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNS-CYIKNKEIFCKMDYFSRFG 157
C C I DRY LK + WH CL C +C L + Y K C+ DY FG
Sbjct: 30 CGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFG 89
Query: 158 TK--CARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLC 210
CA C ++I A + R + YHL CF C +C++ G+ + L+ ++C
Sbjct: 90 QDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVC 144
Score = 33.5 bits (75), Expect = 0.34
Identities = 13/57 (22%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 98 ICSSCGLEILDRYL-LKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYF 153
+C+SC I + ++V + ++H+ C +C+ C+ + + N +I C+ D +
Sbjct: 93 LCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQDIY 149
>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
Length = 746
Score = 75.5 bits (184), Expect = 8e-14
Identities = 43/131 (32%), Positives = 58/131 (44%), Gaps = 4/131 (3%)
Query: 99 CSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGT 158
C CG E +L+V +H++C C VC L Q +IKN E C +DY +GT
Sbjct: 39 CHKCG-EPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQ-GGFFIKNGEYLCTLDYQRMYGT 96
Query: 159 KCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMI 218
+C CG + V A G YH CFAC CKR G+ LC++ M
Sbjct: 97 RCHGCGE--FVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMS 154
Query: 219 ENLKRAAENGN 229
+ K + N
Sbjct: 155 SSPKETTFSSN 165
Score = 62.8 bits (151), Expect = 5e-10
Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 6/124 (4%)
Query: 81 VCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCY 140
+C+ P ++S + + C+ CG +I + L + WH+ C +C C L + Y
Sbjct: 148 LCAQPMSSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE---Y 204
Query: 141 I-KNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGE 199
I K+ +C+ DY FG KC C + + + V A YH +C C C + + GE
Sbjct: 205 ISKDGAPYCEKDYQGLFGVKCEACHQ--FITGKVLEAGDKHYHPSCARCSRCNQMFTEGE 262
Query: 200 EFGL 203
E L
Sbjct: 263 EMYL 266
>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
Length = 718
Score = 75.5 bits (184), Expect = 8e-14
Identities = 43/131 (32%), Positives = 58/131 (44%), Gaps = 4/131 (3%)
Query: 99 CSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGT 158
C CG E +L+V +H++C C VC L Q +IKN E C +DY +GT
Sbjct: 39 CHKCG-EPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQ-GGFFIKNGEYLCTLDYQRMYGT 96
Query: 159 KCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMI 218
+C CG + V A G YH CFAC CKR G+ LC++ M
Sbjct: 97 RCHGCGE--FVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMS 154
Query: 219 ENLKRAAENGN 229
+ K + N
Sbjct: 155 SSPKETTFSSN 165
Score = 62.8 bits (151), Expect = 5e-10
Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 6/124 (4%)
Query: 81 VCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCY 140
+C+ P ++S + + C+ CG +I + L + WH+ C +C C L + Y
Sbjct: 148 LCAQPMSSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE---Y 204
Query: 141 I-KNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGE 199
I K+ +C+ DY FG KC C + + + V A YH +C C C + + GE
Sbjct: 205 ISKDGAPYCEKDYQGLFGVKCEACHQ--FITGKVLEAGDKHYHPSCARCSRCNQMFTEGE 262
Query: 200 EFGL 203
E L
Sbjct: 263 EMYL 266
>gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]
Length = 778
Score = 75.5 bits (184), Expect = 8e-14
Identities = 43/131 (32%), Positives = 58/131 (44%), Gaps = 4/131 (3%)
Query: 99 CSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGT 158
C CG E +L+V +H++C C VC L Q +IKN E C +DY +GT
Sbjct: 99 CHKCG-EPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQ-GGFFIKNGEYLCTLDYQRMYGT 156
Query: 159 KCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMI 218
+C CG + V A G YH CFAC CKR G+ LC++ M
Sbjct: 157 RCHGCGE--FVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMS 214
Query: 219 ENLKRAAENGN 229
+ K + N
Sbjct: 215 SSPKETTFSSN 225
Score = 62.8 bits (151), Expect = 5e-10
Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 6/124 (4%)
Query: 81 VCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCY 140
+C+ P ++S + + C+ CG +I + L + WH+ C +C C L + Y
Sbjct: 208 LCAQPMSSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE---Y 264
Query: 141 I-KNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGE 199
I K+ +C+ DY FG KC C + + + V A YH +C C C + + GE
Sbjct: 265 ISKDGAPYCEKDYQGLFGVKCEACHQ--FITGKVLEAGDKHYHPSCARCSRCNQMFTEGE 322
Query: 200 EFGL 203
E L
Sbjct: 323 EMYL 326
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 73.6 bits (179), Expect = 3e-13
Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Query: 99 CSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGT 158
C+ C +I ++ + WHV C C+ C+T +R + + Y++ +C+ DY FGT
Sbjct: 307 CAKCKKKITGE-IMHALKMTWHVHCFTCAACKTPIRNR-AFYMEEGVPYCERDYEKMFGT 364
Query: 159 KCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIH 213
KC C +I A D A G ++H CF C C+ L G+ F +++ LC+ H
Sbjct: 365 KCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLE-GKTFYSKKDRPLCKSH 418
Score = 60.8 bits (146), Expect = 2e-09
Identities = 53/214 (24%), Positives = 81/214 (37%), Gaps = 13/214 (6%)
Query: 12 LPEGCRLPAEGGPATDQVMAQ---PGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDE 68
L + ++P PA Q PG + T PA A+ A +
Sbjct: 153 LKKSSQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAERYAPDKTSTVLTRH 212
Query: 69 GQASPCTPSTPSVCSPPSAASSVPSAGKN-----ICSSCGLEILDRYLLKVNNLIWHVRC 123
Q + TP +AA VP G N +C C I RYL+ + + +H
Sbjct: 213 SQPATPTPLQSRTSIVQAAAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHA-YHPEE 271
Query: 124 LECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHL 183
CS C L ++ + + IFC Y R+ CA+C ++I + A +H+
Sbjct: 272 FVCSQCGKVL-EEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGE--IMHALKMTWHV 328
Query: 184 ACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTM 217
CF C +CK + F + E C Y+ M
Sbjct: 329 HCFTCAACKTPI-RNRAFYMEEGVPYCERDYEKM 361
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 73.6 bits (179), Expect = 3e-13
Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Query: 99 CSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGT 158
C+ C +I ++ + WHV C C+ C+T +R + + Y++ +C+ DY FGT
Sbjct: 341 CAKCKKKITGE-IMHALKMTWHVHCFTCAACKTPIRNR-AFYMEEGVPYCERDYEKMFGT 398
Query: 159 KCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIH 213
KC C +I A D A G ++H CF C C+ L G+ F +++ LC+ H
Sbjct: 399 KCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLE-GKTFYSKKDRPLCKSH 452
Score = 60.8 bits (146), Expect = 2e-09
Identities = 53/214 (24%), Positives = 81/214 (37%), Gaps = 13/214 (6%)
Query: 12 LPEGCRLPAEGGPATDQVMAQ---PGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDE 68
L + ++P PA Q PG + T PA A+ A +
Sbjct: 187 LKKSSQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAERYAPDKTSTVLTRH 246
Query: 69 GQASPCTPSTPSVCSPPSAASSVPSAGKN-----ICSSCGLEILDRYLLKVNNLIWHVRC 123
Q + TP +AA VP G N +C C I RYL+ + + +H
Sbjct: 247 SQPATPTPLQSRTSIVQAAAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHA-YHPEE 305
Query: 124 LECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHL 183
CS C L ++ + + IFC Y R+ CA+C ++I + A +H+
Sbjct: 306 FVCSQCGKVL-EEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGE--IMHALKMTWHV 362
Query: 184 ACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTM 217
CF C +CK + F + E C Y+ M
Sbjct: 363 HCFTCAACKTPI-RNRAFYMEEGVPYCERDYEKM 395
>gi|7662330 actin binding LIM protein family, member 3 [Homo
sapiens]
Length = 683
Score = 70.5 bits (171), Expect = 3e-12
Identities = 43/129 (33%), Positives = 58/129 (44%), Gaps = 7/129 (5%)
Query: 82 CSPPSAASS-VPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCY 140
CS A+S + G + C+ C EI L + WHV C +C C L + Y
Sbjct: 133 CSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQTCSVILTGE---Y 189
Query: 141 IKNKEI-FCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGE 199
I + +C+ DY ++FG KC C R Y S V A G YH C C C + + GE
Sbjct: 190 ISKDGVPYCESDYHAQFGIKCETCDR--YISGRVLEAGGKHYHPTCARCVRCHQMFTEGE 247
Query: 200 EFGLVEEKV 208
E L +V
Sbjct: 248 EMYLTGSEV 256
Score = 68.9 bits (167), Expect = 7e-12
Identities = 36/122 (29%), Positives = 60/122 (49%), Gaps = 6/122 (4%)
Query: 92 PSAGKNI--CSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCK 149
P N+ C CG + +++V+N +H+RC C VC L Q + + KN+E C
Sbjct: 14 PRGSSNVIQCYRCG-DTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQ-SGFFFKNQEYICT 71
Query: 150 MDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVL 209
DY +GT+C C + + + V A G YH CF C C++ G++ ++ +
Sbjct: 72 QDYQQLYGTRCDSC--RDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECV 129
Query: 210 CR 211
C+
Sbjct: 130 CQ 131
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 70.1 bits (170), Expect = 3e-12
Identities = 38/115 (33%), Positives = 55/115 (47%), Gaps = 3/115 (2%)
Query: 99 CSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGT 158
C C +IL + + WHV C C C +R N ++++ E +C+ DY++ FGT
Sbjct: 370 CGRCQRKILGEVISALKQT-WHVSCFVCVACGKPIRN-NVFHLEDGEPYCETDYYALFGT 427
Query: 159 KCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIH 213
C C I A D A G +H CF C C L G+ F ++K LC+ H
Sbjct: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLE-GQTFFSKKDKPLCKKH 481
Score = 48.9 bits (115), Expect = 8e-06
Identities = 46/227 (20%), Positives = 87/227 (38%), Gaps = 20/227 (8%)
Query: 11 ALPEGCRLPAEGGPATDQVMAQPGSGCKATTRCLEGTA--------PPAMAQSDAEALAG 62
++PE P G P + A +T ++ + P S++ +G
Sbjct: 216 SMPESLDSPTSGRPGVTSLTAAAAFKPVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSG 275
Query: 63 ALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGKN--ICSSCGLEILDRYLLKVNNLIWH 120
++ PS A +P AGK +C+ C I +L+ + WH
Sbjct: 276 SVAPANSALGQTQPSDQDTLV--QRAEHIP-AGKRTPMCAHCNQVIRGPFLVALGKS-WH 331
Query: 121 VRCLECSVCRTSLRQQNSCYIKNK-EIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGN 179
C+ C+ ++ +++ K ++C++ Y F +C RC R+I V A
Sbjct: 332 PEEFNCAHCKNTMAYIG--FVEEKGALYCELCYEKFFAPECGRCQRKILGE--VISALKQ 387
Query: 180 AYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAE 226
+H++CF C +C + + F L + + C Y + + E
Sbjct: 388 TWHVSCFVCVACGKPI-RNNVFHLEDGEPYCETDYYALFGTICHGCE 433
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.132 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,032,540
Number of Sequences: 37866
Number of extensions: 911262
Number of successful extensions: 5752
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 313
Number of HSP's successfully gapped in prelim test: 160
Number of HSP's that attempted gapping in prelim test: 4747
Number of HSP's gapped (non-prelim): 834
length of query: 392
length of database: 18,247,518
effective HSP length: 104
effective length of query: 288
effective length of database: 14,309,454
effective search space: 4121122752
effective search space used: 4121122752
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.