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Search of human proteins with 55956899
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55956899 keratin 9 [Homo sapiens]
(623 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55956899 keratin 9 [Homo sapiens] 1268 0.0
gi|195972866 keratin 10 [Homo sapiens] 598 e-171
gi|24430190 keratin 15 [Homo sapiens] 438 e-123
gi|15431310 keratin 14 [Homo sapiens] 436 e-122
gi|192807292 keratin 24 [Homo sapiens] 434 e-121
gi|24430192 keratin 16 [Homo sapiens] 432 e-121
gi|131412228 keratin 13 isoform b [Homo sapiens] 431 e-120
gi|131412225 keratin 13 isoform a [Homo sapiens] 431 e-120
gi|4557699 keratin 12 [Homo sapiens] 400 e-111
gi|4557701 keratin 17 [Homo sapiens] 375 e-104
gi|24234699 keratin 19 [Homo sapiens] 369 e-102
gi|153945736 keratin 27 [Homo sapiens] 342 6e-94
gi|119395750 keratin 1 [Homo sapiens] 340 2e-93
gi|114431246 keratin 25D [Homo sapiens] 340 3e-93
gi|31559829 keratin 25 [Homo sapiens] 339 4e-93
gi|31559815 keratin 26 [Homo sapiens] 317 2e-86
gi|47132620 keratin 2 [Homo sapiens] 313 3e-85
gi|4504927 keratin 36 [Homo sapiens] 303 4e-82
gi|94538345 keratin 35 [Homo sapiens] 300 3e-81
gi|27894337 keratin 20 [Homo sapiens] 287 2e-77
gi|109148552 keratin 3 [Homo sapiens] 282 7e-76
gi|27894339 keratin 23 [Homo sapiens] 274 2e-73
gi|116488398 keratin 32 [Homo sapiens] 272 6e-73
gi|148277620 type I hair keratin KA35 [Homo sapiens] 270 2e-72
gi|153791670 keratin 76 [Homo sapiens] 270 3e-72
gi|40354195 keratin 18 [Homo sapiens] 270 3e-72
gi|4557888 keratin 18 [Homo sapiens] 270 3e-72
gi|10337581 type I hair keratin 3B [Homo sapiens] 270 3e-72
gi|14917115 keratin 31 [Homo sapiens] 270 3e-72
gi|14917117 keratin 33A [Homo sapiens] 270 4e-72
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 1268 bits (3281), Expect = 0.0
Identities = 623/623 (100%), Positives = 623/623 (100%)
Query: 1 MSCRQFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRV 60
MSCRQFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRV
Sbjct: 1 MSCRQFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRV 60
Query: 61 CGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSG 120
CGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSG
Sbjct: 61 CGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSG 120
Query: 121 GGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRLASYLDKVQALEEANND 180
GGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRLASYLDKVQALEEANND
Sbjct: 121 GGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRLASYLDKVQALEEANND 180
Query: 181 LENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFR 240
LENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFR
Sbjct: 181 LENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFR 240
Query: 241 IKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLT 300
IKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLT
Sbjct: 241 IKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLT 300
Query: 301 GQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSG 360
GQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSG
Sbjct: 301 GQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSG 360
Query: 361 QEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLE 420
QEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLE
Sbjct: 361 QEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLE 420
Query: 421 AQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEGGQEDFESSGAGKIGLGGRGG 480
AQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEGGQEDFESSGAGKIGLGGRGG
Sbjct: 421 AQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEGGQEDFESSGAGKIGLGGRGG 480
Query: 481 SGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGG 540
SGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGG
Sbjct: 481 SGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGG 540
Query: 541 GHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSY 600
GHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSY
Sbjct: 541 GHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSY 600
Query: 601 GGGEEASGSGGGYGGGSGKSSHS 623
GGGEEASGSGGGYGGGSGKSSHS
Sbjct: 601 GGGEEASGSGGGYGGGSGKSSHS 623
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 598 bits (1542), Expect = e-171
Identities = 348/621 (56%), Positives = 406/621 (65%), Gaps = 45/621 (7%)
Query: 1 MSCRQFSSSYLSRS-GGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSR 59
MS R SS + S S GGGGGG G GG S R SSS G GGG FSS GG SR
Sbjct: 1 MSVRYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGG-FSSGGFSGGSFSR 59
Query: 60 VCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGS-RGFGGASGGGYSSSGGFGGG-FGG 117
G GGG F GGS GG+ GGFGGGS RG G+S G S G FGGG FGG
Sbjct: 60 --GSSGGGCF-----GGSSGGYGGL---GGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGG 109
Query: 118 GS--GGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRLASYLDKVQALE 175
GS GG FGGG G G GGFGG GG GGDGG+L+ NEK TMQ LN RLASYLDKV+ALE
Sbjct: 110 GSFGGGSFGGG-GFGGGGFGGGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALE 168
Query: 176 EANNDLENKIQDWYDKKGPA--AIQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTR 233
E+N +LE KI++WY+K G + ++YS YY TIDDLK+QI++LT N LL IDN R
Sbjct: 169 ESNYELEGKIKEWYEKHGNSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNAR 228
Query: 234 MTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKNHK 293
+ DDFR+K+E E LRQ V+ADINGLR+VLD LT+ K+DLEMQ E+L EEL LKKNH+
Sbjct: 229 LAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHE 288
Query: 294 EEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIE 353
EEM L ++GDVNVE+N APG DLT+ LN+MR +YEQL +NRKD E + + ++
Sbjct: 289 EEMKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELT 348
Query: 354 HEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQ 413
E+ ++ +++ S E+T+LR VQ LEIELQSQL+ K +LE SL +T+ RYC QL IQ
Sbjct: 349 TEIDNNIEQISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQ 408
Query: 414 EQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEGGQEDFESSGAGKI 473
QIS LE Q+ +R E ECQN EY LL IK+RLE EI+TY +LLE G G
Sbjct: 409 AQISALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLE---------GEGSS 459
Query: 474 GLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGG 533
G GGRG GGS+G G GGS GGG SGGG+GGG G G SGG YGGGS GG SGGG
Sbjct: 460 GGGGRG--GGSFGGGY---GGGSSGGGSSGGGHGGGHG--GSSGGGYGGGSSGGGSSGGG 512
Query: 534 YGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGG-SGSRGGSGGSHGGGSGF 592
YGGGS S GGH G S G YGGG S GG GGGYGGG SG SGG +GGGS
Sbjct: 513 YGGGS-------SSGGHGGSSSGGYGGG--SSGGGGGGYGGGSSGGGSSSGGGYGGGSSS 563
Query: 593 GGESGGSYGGGEEASGSGGGY 613
GG S G E+S G Y
Sbjct: 564 GGHKSSSSGSVGESSSKGPRY 584
Score = 116 bits (290), Expect = 7e-26
Identities = 76/143 (53%), Positives = 82/143 (57%), Gaps = 13/143 (9%)
Query: 481 SGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYG-GGSG 539
S + SR G GG GGGG GGG G S S GS GGG SGG SGG + G SG
Sbjct: 6 SSSKHYSSSRSGGGG--GGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSG 63
Query: 540 GGHSGGSGGGHSGGSGGNYGGGS--GSGGGS--GGGYGGGSGSRGGSGGSHGGGSGFGGE 595
GG GGS GG+ GG GG +GGGS GS G S GG YGG G GGS GGGS FG
Sbjct: 64 GGCFGGSSGGY-GGLGG-FGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGS-FG-- 118
Query: 596 SGGSYGGGEEASGSGGGYGGGSG 618
GG +GGG G GGG+GG G
Sbjct: 119 -GGGFGGGGFGGGFGGGFGGDGG 140
Score = 85.1 bits (209), Expect = 2e-16
Identities = 48/109 (44%), Positives = 52/109 (47%), Gaps = 6/109 (5%)
Query: 513 RGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGY 572
R S Y GGG GGG GGG GG S G+ GGG SGG SGG +
Sbjct: 4 RYSSSKHYSSSRSGGGGGGGGCGGG------GGVSSLRISSSKGSLGGGFSSGGFSGGSF 57
Query: 573 GGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSS 621
GS G GGS GG G GG GGS+ G +S GG YGG G S
Sbjct: 58 SRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGS 106
Score = 32.7 bits (73), Expect = 1.0
Identities = 17/30 (56%), Positives = 17/30 (56%), Gaps = 1/30 (3%)
Query: 595 ESGGSYGGGEEASGS-GGGYGGGSGKSSHS 623
E GS GGG GS GGGYGGGS S
Sbjct: 454 EGEGSSGGGGRGGGSFGGGYGGGSSGGGSS 483
Score = 30.8 bits (68), Expect = 3.9
Identities = 18/48 (37%), Positives = 19/48 (39%)
Query: 576 SGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSSHS 623
S S+ S GGG G GG GG S S G GGG S
Sbjct: 6 SSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFS 53
>gi|24430190 keratin 15 [Homo sapiens]
Length = 456
Score = 438 bits (1127), Expect = e-123
Identities = 236/441 (53%), Positives = 305/441 (69%), Gaps = 22/441 (4%)
Query: 48 SSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSS 107
+SSS +GGGS+R GGS GGGF SL GG GGSR +S SS
Sbjct: 8 TSSSTFGGGSTR------GGSLL-----AGGGGFGGGSLSGG--GGSRSISASSARFVSS 54
Query: 108 S--GGFGGG-----FGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQEL 160
GG+GGG FGGG+G FGGG+G G GG GFGGG GGGDGG+L+ NEK TMQ L
Sbjct: 55 GSGGGYGGGMRVCGFGGGAGSVFGGGFGGGVGG--GFGGGFGGGDGGLLSGNEKITMQNL 112
Query: 161 NSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVDLTV 220
N RLASYLDKV+ALEEAN DLE KI DWY K+ P + + +YS Y+ TI++L+D+I+ T+
Sbjct: 113 NDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTI 172
Query: 221 GNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYET 280
N++ +L+IDN R+ DDFR+K+E E LRQGV+ADINGLR+VLD LT+ ++DLEMQ E
Sbjct: 173 DNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEG 232
Query: 281 LQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKD 340
L EEL LKKNH+EEM + + Q +G VNVE++ APG DLT+ L +MR++YE + KNR+D
Sbjct: 233 LNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRD 292
Query: 341 IENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLED 400
+E + ++ ++ EV+S+ + +Q+S E+T LR +QELEIELQSQLS KA LE SL +
Sbjct: 293 VEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAE 352
Query: 401 TKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEG 460
T+ RY QLQ IQ I LEAQ++++R E+E QNQEY +LL IK RLE+EI TY +LLEG
Sbjct: 353 TECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEG 412
Query: 461 GQEDFESSGAGKIGLGGRGGS 481
G + GG G S
Sbjct: 413 QDAKMAGIGIREASSGGGGSS 433
Score = 80.5 bits (197), Expect = 4e-15
Identities = 47/95 (49%), Positives = 52/95 (54%), Gaps = 15/95 (15%)
Query: 481 SGGSYGRGS-RGGSGGSYGGGGSGGGYGGGSGSR-----------GGSGGSYGGG---SG 525
S ++G GS RGGS + GGG GG GG GSR GSGG YGGG G
Sbjct: 9 SSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRVCG 68
Query: 526 SGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGG 560
GGG+G +GGG GGG GG GGG GG GG G
Sbjct: 69 FGGGAGSVFGGGFGGGVGGGFGGGFGGGDGGLLSG 103
Score = 79.3 bits (194), Expect = 1e-14
Identities = 51/102 (50%), Positives = 57/102 (55%), Gaps = 16/102 (15%)
Query: 516 SGGSYGGGSGSGGG---SGGGYGGGS---GGGH---SGGSGGGHSGGSGGNYGGG---SG 563
S ++GGGS GG GGG+GGGS GGG S S S GSGG YGGG G
Sbjct: 9 SSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRVCG 68
Query: 564 SGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEE 605
GGG+G +GGG G GG GG GG GFGG GG G E+
Sbjct: 69 FGGGAGSVFGGGFG--GGVGGGFGG--GFGGGDGGLLSGNEK 106
Score = 78.6 bits (192), Expect = 2e-14
Identities = 49/94 (52%), Positives = 55/94 (58%), Gaps = 10/94 (10%)
Query: 502 SGGGYGGGSGSRGGS----GGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGG- 556
S +GGGS +RGGS GG +GGGS SGGG S S GSGGG+ GG
Sbjct: 9 SSSTFGGGS-TRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRVC 67
Query: 557 NYGGGSGS--GGGSGGGYGGGSGSRGGSGGSHGG 588
+GGG+GS GGG GGG GGG G GG GG GG
Sbjct: 68 GFGGGAGSVFGGGFGGGVGGGFG--GGFGGGDGG 99
Score = 74.7 bits (182), Expect = 2e-13
Identities = 46/90 (51%), Positives = 50/90 (55%), Gaps = 20/90 (22%)
Query: 478 RGGS----GGSYGRGSRGGSGGS---------YGGGGSGGGYGGGSGSRGGSGGSYGGGS 524
RGGS GG +G GS G GGS + GSGGGYGGG G +GGG+
Sbjct: 19 RGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRVCG-----FGGGA 73
Query: 525 GS--GGGSGGGYGGGSGGGHSGGSGGGHSG 552
GS GGG GGG GGG GGG GG GG SG
Sbjct: 74 GSVFGGGFGGGVGGGFGGGFGGGDGGLLSG 103
Score = 73.6 bits (179), Expect = 5e-13
Identities = 44/95 (46%), Positives = 50/95 (52%), Gaps = 15/95 (15%)
Query: 493 SGGSYGGGGS--------GGGYGGGSGSRGGSGGSYGGGSGS--GGGSGGGYGGGSGGGH 542
S ++GGG + GGG+GGGS S GG S S GSGGGYGGG
Sbjct: 9 SSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGM---R 65
Query: 543 SGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSG 577
G GGG GG +GG G GGG GGG+GGG G
Sbjct: 66 VCGFGGGAGSVFGGGFGG--GVGGGFGGGFGGGDG 98
Score = 68.2 bits (165), Expect = 2e-11
Identities = 46/102 (45%), Positives = 53/102 (51%), Gaps = 12/102 (11%)
Query: 451 IETYHNLLEGGQEDFESSGAGKIGLGGRGGSGG--------SYGRGSRGGSGGSYGGGGS 502
++T + GG S AG G GG SGG S R GSGG YGGG
Sbjct: 6 LQTSSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMR 65
Query: 503 GGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSG 544
G+GGG+GS GG +GG G GGG GGG+GGG GG SG
Sbjct: 66 VCGFGGGAGS--VFGGGFGG--GVGGGFGGGFGGGDGGLLSG 103
Score = 39.7 bits (91), Expect = 0.008
Identities = 25/55 (45%), Positives = 30/55 (54%), Gaps = 8/55 (14%)
Query: 465 FESSGAGKIGLGGR-------GGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGS 512
F SSG+G G GG GG+G +G G GG GG +GGG GG G SG+
Sbjct: 51 FVSSGSGG-GYGGGMRVCGFGGGAGSVFGGGFGGGVGGGFGGGFGGGDGGLLSGN 104
>gi|15431310 keratin 14 [Homo sapiens]
Length = 472
Score = 436 bits (1120), Expect = e-122
Identities = 241/442 (54%), Positives = 298/442 (67%), Gaps = 20/442 (4%)
Query: 29 RSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGY--SYGGGSGGGFSASSL 86
R S S G G GG G GGGSSR+ GGS +YGGG S S
Sbjct: 6 RQFTSSSSMKGSCGIGG------GIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSS 59
Query: 87 GGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDG 146
GG +G G GG GG SSS FG GFGGG GGG G G G GGFGGG GGDG
Sbjct: 60 GGAYGLG----GGYGGGFSSSSSSFGSGFGGGYGGGLGAGLG------GGFGGGFAGGDG 109
Query: 147 GILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYN 206
+L +EK TMQ LN RLASYLDKV+ALEEAN DLE KI+DWY ++ PA I K+YSPY+
Sbjct: 110 -LLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEI-KDYSPYFK 167
Query: 207 TIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDN 266
TI+DL+++I+ TV N LL IDN R+ DDFR K+E E NLR V+ADINGLR+VLD
Sbjct: 168 TIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDE 227
Query: 267 LTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDM 326
LT+ ++DLEMQ E+L+EEL LKKNH+EEM+ L GQ GDVNVE++ APG DL++ LN+M
Sbjct: 228 LTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEM 287
Query: 327 RQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQS 386
R +YE++ KNRKD E + T+ ++ EV+++ + VQS E+++LR +Q LEIELQS
Sbjct: 288 RDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQS 347
Query: 387 QLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMR 446
QLS KA+LE SLE+TK RYC QL IQE I ++E Q+ +R E+E QNQEY +LL +K R
Sbjct: 348 QLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTR 407
Query: 447 LEKEIETYHNLLEGGQEDFESS 468
LE+EI TY LLEG SS
Sbjct: 408 LEQEIATYRRLLEGEDAHLSSS 429
Score = 77.4 bits (189), Expect = 4e-14
Identities = 48/107 (44%), Positives = 55/107 (51%), Gaps = 3/107 (2%)
Query: 465 FESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGS 524
F SS + K G GG GG R S +GGS + GG S SR SGG+YG G
Sbjct: 8 FTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLGG 67
Query: 525 GSGGG---SGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGS 568
G GGG S +G G GGG+ GG G G GG GG + GG G GS
Sbjct: 68 GYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGS 114
Score = 71.2 bits (173), Expect = 3e-12
Identities = 50/105 (47%), Positives = 53/105 (50%), Gaps = 16/105 (15%)
Query: 493 SGGSYGGGGSGGGYGGGSGSRGG--SGGS------YGGG---SGSGGGSGGGY--GGGSG 539
S G G GGG GGGS +GGS YGGG S S SGG Y GGG G
Sbjct: 11 SSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLGGGYG 70
Query: 540 GGHSGGSGGGHSGGSGGNYGG--GSGSGGGSGGGYGGGSGSRGGS 582
GG S S G GG YGG G+G GGG GGG+ GG G GS
Sbjct: 71 GGFS-SSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGS 114
Score = 66.2 bits (160), Expect = 8e-11
Identities = 45/99 (45%), Positives = 48/99 (48%), Gaps = 17/99 (17%)
Query: 529 GSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGG---------SGSGGGSGGGYGGGSGSR 579
G GGG GGGS S +GG S YGGG SG G GGGYGGG S
Sbjct: 19 GIGGGIGGGSSRISSVLAGGSCRAPS--TYGGGLSVSSSRFSSGGAYGLGGGYGGGFSSS 76
Query: 580 GGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSG 618
S GS G G G+GG G GG G GGG+ GG G
Sbjct: 77 SSSFGS-GFGGGYGGGLGAGLGG-----GFGGGFAGGDG 109
Score = 65.1 bits (157), Expect = 2e-10
Identities = 42/99 (42%), Positives = 48/99 (48%), Gaps = 10/99 (10%)
Query: 516 SGGSYGGGSGSGGGSGGG-------YGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGS 568
S S G G GGG GGG GGS S GG S + GG G GGG
Sbjct: 10 SSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLGGGY 69
Query: 569 GGGYGGGSGSRG-GSGGSHGG--GSGFGGESGGSYGGGE 604
GGG+ S S G G GG +GG G+G GG GG + GG+
Sbjct: 70 GGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGD 108
Score = 47.8 bits (112), Expect = 3e-05
Identities = 34/84 (40%), Positives = 43/84 (51%), Gaps = 14/84 (16%)
Query: 456 NLLEGGQEDFESSGAGKIGLGG-RGGSGGSYGRGSRGGSGGSYG------GGGSGGGYGG 508
++L GG S+ G + + R SGG+YG G GG GG + G G GGGYGG
Sbjct: 33 SVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLG--GGYGGGFSSSSSSFGSGFGGGYGG 90
Query: 509 GSGSRGGSGGSYGGGSGSGGGSGG 532
G G+ G GG +GGG G G
Sbjct: 91 GLGA--GLGGGFGGG---FAGGDG 109
Score = 45.1 bits (105), Expect = 2e-04
Identities = 33/69 (47%), Positives = 34/69 (49%), Gaps = 8/69 (11%)
Query: 453 TYHNLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRG-GSGGSYGGG---GSGGGYGG 508
TY L F S GA GLGG G G S S G G GG YGGG G GGG+GG
Sbjct: 45 TYGGGLSVSSSRFSSGGA--YGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGG 102
Query: 509 GSGSRGGSG 517
G GG G
Sbjct: 103 GF--AGGDG 109
Score = 41.2 bits (95), Expect = 0.003
Identities = 29/68 (42%), Positives = 32/68 (47%), Gaps = 18/68 (26%)
Query: 567 GSGGGYGGGSGSRGG--SGGSHGGGSGFGG---------ESGGSYGGGEEASGSGGGYGG 615
G GGG GGGS +GGS S +GG SGG+YG GGGYGG
Sbjct: 19 GIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYG-------LGGGYGG 71
Query: 616 GSGKSSHS 623
G SS S
Sbjct: 72 GFSSSSSS 79
>gi|192807292 keratin 24 [Homo sapiens]
Length = 525
Score = 434 bits (1116), Expect = e-121
Identities = 254/515 (49%), Positives = 326/515 (63%), Gaps = 35/515 (6%)
Query: 1 MSCRQFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRV 60
MSC +SS SR+GG + +GGS S+S S G GG SS+ G+ GG+S
Sbjct: 1 MSCSSRASS--SRAGGSSSARVSAGGS---SFSSGSRCGLGG-----SSAQGFRGGASS- 49
Query: 61 CGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSG 120
C GG S ++GG GGGF + S+GGGFGG S SG G+ FGG G G G
Sbjct: 50 CSLSGGSSG--AFGGSFGGGFGSCSVGGGFGGAS-----GSGTGFGGGSSFGGVSGFGRG 102
Query: 121 GGFGGG--YGSGF-GGFGGFGGGAGGG--DGGILTANEKSTMQELNSRLASYLDKVQALE 175
GF G + SG GGF +GGG GGG DGG+ + EK TMQ LN RLA+YLDKV+ALE
Sbjct: 103 SGFCGSSRFSSGATGGFYSYGGGMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALE 162
Query: 176 EANNDLENKIQDWYDKKGPAAIQ----KNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDN 231
EAN DLENKI++WYDK GP + ++YS YY+ I+DL++QI+ TV N +L IDN
Sbjct: 163 EANTDLENKIKEWYDKYGPGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDN 222
Query: 232 TRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKN 291
R+ DDFR+K+E E LRQ V+ADINGLR+VLD+LTM +SDLEMQ E+ EEL L+KN
Sbjct: 223 ARLAADDFRLKYENELCLRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKN 282
Query: 292 HKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQ 351
H+EEM + G + G+V VE+N APG DLTK LNDMR +YE+L +NR++ E ++ Q
Sbjct: 283 HEEEMKNMQGSSGGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSAS 342
Query: 352 IEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQM 411
++ ++S+ S+ E+T+L+ +Q LEIELQSQL+ K++LE +L DT+ Y QL
Sbjct: 343 LQAQISTDAGAATSAKNEITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSE 402
Query: 412 IQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEGGQEDFESSGAG 471
IQ QIS LE +I + E +CQN EY LL IK RLE EIETY LL+G E G+
Sbjct: 403 IQTQISALEEEICQIWGETKCQNAEYKQLLDIKTRLEVEIETYRRLLDG-----EGGGSS 457
Query: 472 KIGLGGRGGSGGSYGRGSRG-GSGGSYGGGGSGGG 505
GGR + GS GSR SG S G SG G
Sbjct: 458 FAEFGGR--NSGSVNMGSRDLVSGDSRSGSCSGQG 490
Score = 92.0 bits (227), Expect = 1e-18
Identities = 55/119 (46%), Positives = 64/119 (53%), Gaps = 10/119 (8%)
Query: 467 SSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGS---GGSYGGG 523
S+G G R G GGS +G RGG+ GGS G +GG G GS GG +GG
Sbjct: 21 SAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFGGSFGGGFGSCSVGGGFGGA 80
Query: 524 SGSGGGSGGG--YGGGSGGGHSGGSGGG---HSGGSGG--NYGGGSGSGGGSGGGYGGG 575
SGSG G GGG +GG SG G G G SG +GG +YGGG G G G GG + GG
Sbjct: 81 SGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVGDGGLFSGG 139
Score = 89.7 bits (221), Expect = 7e-18
Identities = 60/136 (44%), Positives = 69/136 (50%), Gaps = 17/136 (12%)
Query: 487 RGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGS----YGGGSGS---GGGSGGGYGGGSG 539
R S +GGS S GG SGSR G GGS + GG+ S GGS G +GG G
Sbjct: 6 RASSSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFGGSFG 65
Query: 540 GGHSGGS-GGGHSGGSGGNYGGGSGSGGGSGGGYGGGSG-------SRGGSGG--SHGGG 589
GG S GGG G SG G G GS G G+G GSG S G +GG S+GGG
Sbjct: 66 GGFGSCSVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGG 125
Query: 590 SGFGGESGGSYGGGEE 605
G G GG + GGE+
Sbjct: 126 MGGGVGDGGLFSGGEK 141
Score = 84.0 bits (206), Expect = 4e-16
Identities = 55/130 (42%), Positives = 57/130 (43%), Gaps = 4/130 (3%)
Query: 493 SGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGY-GGGSGGGHSGGSGGGHS 551
S S GG S GGS S G G GG S G+ GG S SGGS G
Sbjct: 2 SCSSRASSSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFG 61
Query: 552 GGSGGNYGG---GSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASG 608
G GG +G G G GG SG G G G GS G G GSGF G S S G
Sbjct: 62 GSFGGGFGSCSVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYS 121
Query: 609 SGGGYGGGSG 618
GGG GGG G
Sbjct: 122 YGGGMGGGVG 131
Score = 69.7 bits (169), Expect = 8e-12
Identities = 48/111 (43%), Positives = 55/111 (49%), Gaps = 9/111 (8%)
Query: 516 SGGSYGGGSGSGGGSGGG--YGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYG 573
+ S GGS S S GG + GS G G S G GG+ G GS G GG +G
Sbjct: 7 ASSSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSG-GSSGAFGGSFG 65
Query: 574 GGSGS---RGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSS 621
GG GS GG GG+ G G+GFG GGS GG G G G+ G S SS
Sbjct: 66 GGFGSCSVGGGFGGASGSGTGFG---GGSSFGGVSGFGRGSGFCGSSRFSS 113
Score = 37.0 bits (84), Expect = 0.054
Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 8/68 (11%)
Query: 562 SGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEE-------ASGS-GGGY 613
S + GG S GGS S G G GG S + GG +SG+ GG +
Sbjct: 5 SRASSSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFGGSF 64
Query: 614 GGGSGKSS 621
GGG G S
Sbjct: 65 GGGFGSCS 72
>gi|24430192 keratin 16 [Homo sapiens]
Length = 473
Score = 432 bits (1112), Expect = e-121
Identities = 238/442 (53%), Positives = 299/442 (67%), Gaps = 14/442 (3%)
Query: 29 RSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGG 88
R S S G G GG G GGGSSR+ GGS GGG S SS
Sbjct: 6 RQFTSSSSMKGSCGIGG------GIGGGSSRISSVLAGGSCRAP--STYGGGLSVSSRFS 57
Query: 89 GFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGI 148
GG+ G GG GGG+SSS FG GFGGG GGG G G+G G G GFGGG GGDG +
Sbjct: 58 S--GGACGLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGA--GFGGGFAGGDG-L 112
Query: 149 LTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYNTI 208
L +EK TMQ LN RLASYLDKV+ALEEAN DLE KI+DWY ++ P+ I K+YSPY+ TI
Sbjct: 113 LVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEI-KDYSPYFKTI 171
Query: 209 DDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLT 268
+DL+++I+ T+ N + +L IDN R+ DDFR K+E E LRQ V+AD+NGLR+VLD LT
Sbjct: 172 EDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELT 231
Query: 269 MEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQ 328
+ ++DLEMQ E L+EEL L+KNH+EEM L GQ GDVNVE++ APG DL++ LN+MR
Sbjct: 232 LARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRD 291
Query: 329 EYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQL 388
+YEQ+ KNR+D E + ++ ++ EV+S+ + VQSS EVT+LR +Q LEIELQSQL
Sbjct: 292 QYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQL 351
Query: 389 SKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLE 448
S KA+LE SLE+TK RYC QL IQ I ++E Q+ +R E+E Q+QEY +LL +K RLE
Sbjct: 352 SMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLE 411
Query: 449 KEIETYHNLLEGGQEDFESSGA 470
+EI TY LLEG S A
Sbjct: 412 QEIATYRRLLEGEDAHLSSQQA 433
Score = 75.1 bits (183), Expect = 2e-13
Identities = 49/110 (44%), Positives = 53/110 (48%), Gaps = 7/110 (6%)
Query: 465 FESSGAGKIGLGGRGGSGGSYGRGSRGGSGGS------YGGGGSGGGYGGGSGSRGGSGG 518
F SS + K G GG GG R S +GGS YGGG S SG G GG
Sbjct: 8 FTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFS-SGGACGLGG 66
Query: 519 SYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGS 568
YGGG S G G+GGG GGG G GGG G GG + GG G GS
Sbjct: 67 GYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGS 116
Score = 73.9 bits (180), Expect = 4e-13
Identities = 49/108 (45%), Positives = 54/108 (50%), Gaps = 20/108 (18%)
Query: 493 SGGSYGGGGSGGGYGGGSGSRGG--SGGS------YGGG--------SGSGGGSGGGYGG 536
S G G GGG GGGS +GGS YGGG SG G GGGYGG
Sbjct: 11 SSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACGLGGGYGG 70
Query: 537 GSGGGHSGGS--GGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGS 582
G S GS GGG+ GG G +GGG G+ G GGG+ GG G GS
Sbjct: 71 GFSSSSSFGSGFGGGYGGGLGAGFGGGLGA--GFGGGFAGGDGLLVGS 116
Score = 70.1 bits (170), Expect = 6e-12
Identities = 48/110 (43%), Positives = 53/110 (48%), Gaps = 15/110 (13%)
Query: 516 SGGSYGGGSGSGGGSGGG-------YGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGS 568
S S G G GGG GGG GGS S GGG S S + GG G GGG
Sbjct: 10 SSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPS-TYGGGLSVSSRFSSGGACGLGGGY 68
Query: 569 GGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSG 618
GGG+ S G GG +GGG G G +GGG A G GGG+ GG G
Sbjct: 69 GGGFSSSSSFGSGFGGGYGGGLGAG------FGGGLGA-GFGGGFAGGDG 111
Score = 63.5 bits (153), Expect = 5e-10
Identities = 37/92 (40%), Positives = 46/92 (50%), Gaps = 13/92 (14%)
Query: 456 NLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGG 515
++L GG S+ G + + R SGG+ G GGG GGG+ S G
Sbjct: 33 SVLAGGSCRAPSTYGGGLSVSSRFSSGGACGL-----------GGGYGGGFSSSSSFGSG 81
Query: 516 SGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSG 547
GG YGGG G+ G GGG G G GGG +GG G
Sbjct: 82 FGGGYGGGLGA--GFGGGLGAGFGGGFAGGDG 111
Score = 40.4 bits (93), Expect = 0.005
Identities = 29/61 (47%), Positives = 31/61 (50%), Gaps = 9/61 (14%)
Query: 567 GSGGGYGGGSGSRGG--SGGSHGGGSGFGG----ESGGSYGGGEEASGSGGGYGGGSGKS 620
G GGG GGGS +GGS S +GG S S GG A G GGGYGGG S
Sbjct: 19 GIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGG---ACGLGGGYGGGFSSS 75
Query: 621 S 621
S
Sbjct: 76 S 76
>gi|131412228 keratin 13 isoform b [Homo sapiens]
Length = 420
Score = 431 bits (1107), Expect = e-120
Identities = 227/420 (54%), Positives = 299/420 (71%), Gaps = 22/420 (5%)
Query: 48 SSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGG-----FSASSLGGGFGGG-SRGFGGAS 101
SSS+ YGGG GGGS GGG G F + GG+GGG S GFGG +
Sbjct: 7 SSSASYGGGF-------GGGSC--QLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGA 57
Query: 102 GGGYSSSGGFGGGFGGGSGGGFGGGYGSGF-GGFGGFGGGAGGGDGGILTANEKSTMQEL 160
G G+ GG+GGG GGG GGG GGG+G GF GGF FG DGG+LT NEK TMQ L
Sbjct: 58 GSGFG--GGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGAC----DGGLLTGNEKITMQNL 111
Query: 161 NSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVDLTV 220
N RLASYL+KV+ALEEAN DLE KI+DW+ K+ PA+ +++YSPYY TI++L+D+I+ T+
Sbjct: 112 NDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATI 171
Query: 221 GNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYET 280
NN+ +L+IDN R+ DDFR+K+E E LRQ V+ADINGLR+VLD LT+ K+DLEMQ E+
Sbjct: 172 ENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIES 231
Query: 281 LQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKD 340
L EEL +KKNH+EEM + + Q G VNVE++ PG DLT+ L +MR++YE + +NR+D
Sbjct: 232 LNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRD 291
Query: 341 IENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLED 400
E + + ++ EVS++ +Q+S E+T+LR +Q LEIELQSQLS KA LE ++ +
Sbjct: 292 AEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAE 351
Query: 401 TKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEG 460
T+ RY QLQ IQ IS++EAQ++++R E+ECQNQEY +LL IK RLE+EI TY +LLEG
Sbjct: 352 TECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEG 411
Score = 81.6 bits (200), Expect = 2e-15
Identities = 49/104 (47%), Positives = 53/104 (50%), Gaps = 12/104 (11%)
Query: 503 GGGYGGGSGSRGGSGG-SYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGG 561
GGG+GGGS GG G S GGS GGYGGG G GG+G G GG GG GGG
Sbjct: 13 GGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGG 72
Query: 562 SGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEE 605
G GG GGG+GGG GG FG GG G E+
Sbjct: 73 YG--GGLGGGFGGGFA---------GGFVDFGACDGGLLTGNEK 105
Score = 79.3 bits (194), Expect = 1e-14
Identities = 47/94 (50%), Positives = 49/94 (52%), Gaps = 6/94 (6%)
Query: 493 SGGSYGGGGSGGG--YGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGH 550
S SYGGG GG GGG G S GGS GG GGG G GGG G GGG+
Sbjct: 8 SSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSA--GGYGGGVSCGFGGGAGSGFGGGY 65
Query: 551 SGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGG 584
GG GG YGG G GGG GGG+ GG G G
Sbjct: 66 GGGLGGGYGG--GLGGGFGGGFAGGFVDFGACDG 97
Score = 76.6 bits (187), Expect = 6e-14
Identities = 51/106 (48%), Positives = 56/106 (52%), Gaps = 10/106 (9%)
Query: 516 SGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGG--SGSGGGSGGGYG 573
S SYGGG G G GG G G S S SGGS G YGGG G GGG+G G+G
Sbjct: 8 SSASYGGGFGGGSCQLGG-----GRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFG 62
Query: 574 GGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGK 619
GG G GG GG +GGG G GG GG GG + GG G+ K
Sbjct: 63 GGYG--GGLGGGYGGGLG-GGFGGGFAGGFVDFGACDGGLLTGNEK 105
Score = 73.9 bits (180), Expect = 4e-13
Identities = 43/77 (55%), Positives = 46/77 (59%), Gaps = 5/77 (6%)
Query: 469 GAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGG 528
G G LGG G R GGS G YGGG S G +GGG+GS G GG YGG G GG
Sbjct: 17 GGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCG-FGGGAGS--GFGGGYGG--GLGG 71
Query: 529 GSGGGYGGGSGGGHSGG 545
G GGG GGG GGG +GG
Sbjct: 72 GYGGGLGGGFGGGFAGG 88
Score = 71.2 bits (173), Expect = 3e-12
Identities = 45/99 (45%), Positives = 47/99 (47%), Gaps = 20/99 (20%)
Query: 481 SGGSYGRGSRGGS---GGSYG---------GGGSGGGYGGGSGSRGGSGGSYGGGSGSGG 528
S SYG G GGS GG G GGS GGYGGG G GG G
Sbjct: 8 SSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSC--GFGGGAGS------ 59
Query: 529 GSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGG 567
G GGGYGGG GGG+ GG GGG GG G + GG
Sbjct: 60 GFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGG 98
Score = 57.0 bits (136), Expect = 5e-08
Identities = 32/77 (41%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
Query: 460 GGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYG---GGGSGGGYGGGSGSRGGS 516
GG + + G GG GG G GG+G +G GGG GGGYGGG G GG
Sbjct: 24 GGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLG--GGF 81
Query: 517 GGSYGGGSGSGGGSGGG 533
GG + GG G GG
Sbjct: 82 GGGFAGGFVDFGACDGG 98
Score = 47.4 bits (111), Expect = 4e-05
Identities = 25/57 (43%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 471 GKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSG 527
G + G GG+G +G G GG GG YGGG GGG+GGG G+ GG +G
Sbjct: 47 GGVSCGFGGGAGSGFGGGYGGGLGGGYGGG-LGGGFGGGFAGGFVDFGACDGGLLTG 102
>gi|131412225 keratin 13 isoform a [Homo sapiens]
Length = 458
Score = 431 bits (1107), Expect = e-120
Identities = 227/420 (54%), Positives = 299/420 (71%), Gaps = 22/420 (5%)
Query: 48 SSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGG-----FSASSLGGGFGGG-SRGFGGAS 101
SSS+ YGGG GGGS GGG G F + GG+GGG S GFGG +
Sbjct: 7 SSSASYGGGF-------GGGSC--QLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGA 57
Query: 102 GGGYSSSGGFGGGFGGGSGGGFGGGYGSGF-GGFGGFGGGAGGGDGGILTANEKSTMQEL 160
G G+ GG+GGG GGG GGG GGG+G GF GGF FG DGG+LT NEK TMQ L
Sbjct: 58 GSGFG--GGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGAC----DGGLLTGNEKITMQNL 111
Query: 161 NSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVDLTV 220
N RLASYL+KV+ALEEAN DLE KI+DW+ K+ PA+ +++YSPYY TI++L+D+I+ T+
Sbjct: 112 NDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATI 171
Query: 221 GNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYET 280
NN+ +L+IDN R+ DDFR+K+E E LRQ V+ADINGLR+VLD LT+ K+DLEMQ E+
Sbjct: 172 ENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIES 231
Query: 281 LQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKD 340
L EEL +KKNH+EEM + + Q G VNVE++ PG DLT+ L +MR++YE + +NR+D
Sbjct: 232 LNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRD 291
Query: 341 IENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLED 400
E + + ++ EVS++ +Q+S E+T+LR +Q LEIELQSQLS KA LE ++ +
Sbjct: 292 AEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAE 351
Query: 401 TKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEG 460
T+ RY QLQ IQ IS++EAQ++++R E+ECQNQEY +LL IK RLE+EI TY +LLEG
Sbjct: 352 TECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEG 411
Score = 81.6 bits (200), Expect = 2e-15
Identities = 49/104 (47%), Positives = 53/104 (50%), Gaps = 12/104 (11%)
Query: 503 GGGYGGGSGSRGGSGG-SYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGG 561
GGG+GGGS GG G S GGS GGYGGG G GG+G G GG GG GGG
Sbjct: 13 GGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGG 72
Query: 562 SGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEE 605
G GG GGG+GGG GG FG GG G E+
Sbjct: 73 YG--GGLGGGFGGGFA---------GGFVDFGACDGGLLTGNEK 105
Score = 79.3 bits (194), Expect = 1e-14
Identities = 47/94 (50%), Positives = 49/94 (52%), Gaps = 6/94 (6%)
Query: 493 SGGSYGGGGSGGG--YGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGH 550
S SYGGG GG GGG G S GGS GG GGG G GGG G GGG+
Sbjct: 8 SSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSA--GGYGGGVSCGFGGGAGSGFGGGY 65
Query: 551 SGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGG 584
GG GG YGG G GGG GGG+ GG G G
Sbjct: 66 GGGLGGGYGG--GLGGGFGGGFAGGFVDFGACDG 97
Score = 76.6 bits (187), Expect = 6e-14
Identities = 51/106 (48%), Positives = 56/106 (52%), Gaps = 10/106 (9%)
Query: 516 SGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGG--SGSGGGSGGGYG 573
S SYGGG G G GG G G S S SGGS G YGGG G GGG+G G+G
Sbjct: 8 SSASYGGGFGGGSCQLGG-----GRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFG 62
Query: 574 GGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGK 619
GG G GG GG +GGG G GG GG GG + GG G+ K
Sbjct: 63 GGYG--GGLGGGYGGGLG-GGFGGGFAGGFVDFGACDGGLLTGNEK 105
Score = 73.9 bits (180), Expect = 4e-13
Identities = 43/77 (55%), Positives = 46/77 (59%), Gaps = 5/77 (6%)
Query: 469 GAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGG 528
G G LGG G R GGS G YGGG S G +GGG+GS G GG YGG G GG
Sbjct: 17 GGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCG-FGGGAGS--GFGGGYGG--GLGG 71
Query: 529 GSGGGYGGGSGGGHSGG 545
G GGG GGG GGG +GG
Sbjct: 72 GYGGGLGGGFGGGFAGG 88
Score = 71.2 bits (173), Expect = 3e-12
Identities = 45/99 (45%), Positives = 47/99 (47%), Gaps = 20/99 (20%)
Query: 481 SGGSYGRGSRGGS---GGSYG---------GGGSGGGYGGGSGSRGGSGGSYGGGSGSGG 528
S SYG G GGS GG G GGS GGYGGG G GG G
Sbjct: 8 SSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSC--GFGGGAGS------ 59
Query: 529 GSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGG 567
G GGGYGGG GGG+ GG GGG GG G + GG
Sbjct: 60 GFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGG 98
Score = 57.0 bits (136), Expect = 5e-08
Identities = 32/77 (41%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
Query: 460 GGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYG---GGGSGGGYGGGSGSRGGS 516
GG + + G GG GG G GG+G +G GGG GGGYGGG G GG
Sbjct: 24 GGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLG--GGF 81
Query: 517 GGSYGGGSGSGGGSGGG 533
GG + GG G GG
Sbjct: 82 GGGFAGGFVDFGACDGG 98
Score = 47.4 bits (111), Expect = 4e-05
Identities = 25/57 (43%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 471 GKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSG 527
G + G GG+G +G G GG GG YGGG GGG+GGG G+ GG +G
Sbjct: 47 GGVSCGFGGGAGSGFGGGYGGGLGGGYGGG-LGGGFGGGFAGGFVDFGACDGGLLTG 102
>gi|4557699 keratin 12 [Homo sapiens]
Length = 494
Score = 400 bits (1029), Expect = e-111
Identities = 210/408 (51%), Positives = 278/408 (68%), Gaps = 23/408 (5%)
Query: 76 GSGGGFSASSLGGGFGGGSRGFGGASGGGYS------SSGGFGGGFGGGSGGGFGGGYG- 128
G G SASS+G G+GG + GFG + GGG+S SS GFGGG G GG G GYG
Sbjct: 28 GRPRGMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGR 87
Query: 129 ----SGFGGFG-GFGGGAGGG--------DGGILTANEKSTMQELNSRLASYLDKVQALE 175
FGG G GFGG GGG DGG+L+ +EK TMQ LN RLASYLDKV+ALE
Sbjct: 88 ALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALE 147
Query: 176 EANNDLENKIQDWYDKKGPA---AIQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNT 232
EAN +LENKI++WY+ +G A Q +YS YY I+DL+++I+ ++GN + LL IDN
Sbjct: 148 EANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNA 207
Query: 233 RMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKNH 292
R+ +DFR+K+E E LRQGV+ADINGLR+VLD LT+ ++DLEMQ E+L EEL +KKNH
Sbjct: 208 RLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNH 267
Query: 293 KEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQI 352
++E+ G+V+VE++ APG DLT+ LNDMR +YE + +NRKD E + + ++
Sbjct: 268 EDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGEL 327
Query: 353 EHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMI 412
E+S++ +++QSS EVT LR Q LEIELQSQL+ K +LE SL + + YC QL +
Sbjct: 328 RKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQV 387
Query: 413 QEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEG 460
Q+ ISNLEAQ+ VR + E QN ++ LL++K RLE EIETY LL+G
Sbjct: 388 QQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDG 435
Score = 71.6 bits (174), Expect = 2e-12
Identities = 51/110 (46%), Positives = 54/110 (49%), Gaps = 13/110 (11%)
Query: 513 RGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGY 572
RG S S G G G GS G+G GGG S S G S G GG G GS GG G GY
Sbjct: 31 RGMSASSVGSGYG---GSAFGFGASCGGGFSAASMFGSSSGFGG--GSGSSMAGGLGAGY 85
Query: 573 GGGSGSRGGSGGSHGG-GSGFGGESGGSYGGGEEASGSGGGYGGGSGKSS 621
G G GGS GG G GFGG GG G SG+ GG GS K +
Sbjct: 86 GRALG-----GGSFGGLGMGFGGSPGG--GSLGILSGNDGGLLSGSEKET 128
Score = 70.5 bits (171), Expect = 4e-12
Identities = 45/110 (40%), Positives = 52/110 (47%), Gaps = 8/110 (7%)
Query: 474 GLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGG--SGGSYGGGSGSGGGSG 531
GL R S GR RG S S G G G +G G+ GG + +G SG GGGSG
Sbjct: 16 GLSRRLSSQSVIGR-PRGMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSG 74
Query: 532 GGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGG 581
GG G G+ GGG GG G +GG G GG G SG+ GG
Sbjct: 75 SSMAGGLGAGYGRALGGGSFGGLGMGFGGSPG-----GGSLGILSGNDGG 119
Score = 66.6 bits (161), Expect = 6e-11
Identities = 44/93 (47%), Positives = 45/93 (48%), Gaps = 10/93 (10%)
Query: 478 RGGSGGSYGRGSRG---GSGGSYGGG-------GSGGGYGGGSGSRGGSGGSYGGGSGSG 527
RG S S G G G G G S GGG GS G+GGGSGS G G G G
Sbjct: 31 RGMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGRALG 90
Query: 528 GGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGG 560
GGS GG G G GG GGS G SG GG G
Sbjct: 91 GGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSG 123
Score = 49.7 bits (117), Expect = 8e-06
Identities = 39/93 (41%), Positives = 42/93 (45%), Gaps = 13/93 (13%)
Query: 460 GGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGS 519
G F +S G GS +G GGSG S GG G GYG G GGS
Sbjct: 44 GSAFGFGASCGGGFSAASMFGSSSGFG----GGSGSSM-AGGLGAGYGRALG-----GGS 93
Query: 520 YGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSG 552
+G G G G GG GGGS G SG GG SG
Sbjct: 94 FG---GLGMGFGGSPGGGSLGILSGNDGGLLSG 123
Score = 35.0 bits (79), Expect = 0.21
Identities = 25/51 (49%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
Query: 467 SSGAGKIGLG-GRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGS 516
SS AG +G G GR GGS+G G G GGS GGG G G G GS
Sbjct: 75 SSMAGGLGAGYGRALGGGSFG-GLGMGFGGSPGGGSLGILSGNDGGLLSGS 124
>gi|4557701 keratin 17 [Homo sapiens]
Length = 432
Score = 375 bits (963), Expect = e-104
Identities = 214/431 (49%), Positives = 277/431 (64%), Gaps = 43/431 (9%)
Query: 30 SSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGG 89
+S +F+SS G SSG GGGSSR R GG G GS SA LG
Sbjct: 3 TSIRQFTSSSSIKG------SSGLGGGSSRTSCRLSGG-----LGAGSCRLGSAGGLGST 51
Query: 90 FGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGIL 149
GG S YSS FG G GGYGS FGG G +L
Sbjct: 52 LGGSS----------YSSCYSFGSG----------GGYGSSFGGVDG-----------LL 80
Query: 150 TANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYNTID 209
EK+TMQ LN RLASYLDKV+ALEEAN +LE KI+DWY ++ P ++YS YY TI+
Sbjct: 81 AGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPA-RDYSQYYRTIE 139
Query: 210 DLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTM 269
+L+++I+ TV N LL IDN R+ DDFR KFE EQ LR V+ADINGLR+VLD LT+
Sbjct: 140 ELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTL 199
Query: 270 EKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQE 329
++DLEMQ E L+EEL LKKNH+EEM+ L GQ G++NVE++ APG DL++ LN+MR +
Sbjct: 200 ARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQ 259
Query: 330 YEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLS 389
YE++ KNRKD E+ + ++ ++ EV+++ + VQS E+++LR +Q LEIELQSQLS
Sbjct: 260 YEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLS 319
Query: 390 KKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEK 449
KA+LE +L +T+NRYC QL IQ I ++E Q+ +R E+E QNQEY +LL +K RLE+
Sbjct: 320 MKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQ 379
Query: 450 EIETYHNLLEG 460
EI TY LLEG
Sbjct: 380 EIATYRRLLEG 390
Score = 45.8 bits (107), Expect = 1e-04
Identities = 30/73 (41%), Positives = 33/73 (45%), Gaps = 7/73 (9%)
Query: 516 SGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGS-------GSGGGS 568
S S G SG GGGS SGG +G G +GG G GG S GSGGG
Sbjct: 10 SSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGY 69
Query: 569 GGGYGGGSGSRGG 581
G +GG G G
Sbjct: 70 GSSFGGVDGLLAG 82
Score = 44.7 bits (104), Expect = 3e-04
Identities = 35/72 (48%), Positives = 37/72 (51%), Gaps = 8/72 (11%)
Query: 543 SGGSGGGHSGGS---GGNYGGGS---GSGGGSGGGYGGGSGSRGGSGGSHGG-GSGFGGE 595
S G GGG S S G G GS GS GG G GG S S S GS GG GS FGG
Sbjct: 17 SSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGYGSSFGGV 76
Query: 596 SGGSYGGGEEAS 607
G GGE+A+
Sbjct: 77 D-GLLAGGEKAT 87
Score = 43.1 bits (100), Expect = 8e-04
Identities = 31/69 (44%), Positives = 34/69 (49%), Gaps = 7/69 (10%)
Query: 487 RGSRG-GSGGSYGGGGSGGGYGGGS---GSRGGSGGSYGGGSGS---GGGSGGGYGGGSG 539
+GS G G G S GG G GS GS GG G + GG S S GSGGGYG G
Sbjct: 15 KGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGYGSSFG 74
Query: 540 GGHSGGSGG 548
G +GG
Sbjct: 75 GVDGLLAGG 83
Score = 40.8 bits (94), Expect = 0.004
Identities = 25/65 (38%), Positives = 27/65 (41%)
Query: 554 SGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGY 613
S + G SG GGGS SG G G G G GGS + GSGGGY
Sbjct: 10 SSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGY 69
Query: 614 GGGSG 618
G G
Sbjct: 70 GSSFG 74
Score = 39.3 bits (90), Expect = 0.011
Identities = 26/60 (43%), Positives = 29/60 (48%), Gaps = 4/60 (6%)
Query: 501 GSGGGYGGGSGSRGGSGGSYGGGS---GSGGGSGGGYGGGS-GGGHSGGSGGGHSGGSGG 556
GS G GG S + G G GS GS GG G GG S +S GSGGG+ GG
Sbjct: 16 GSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGYGSSFGG 75
Score = 38.9 bits (89), Expect = 0.014
Identities = 28/66 (42%), Positives = 30/66 (45%), Gaps = 6/66 (9%)
Query: 477 GRGGSGGSYGRGSRGGSGGSYGGG---GSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGG 533
G G GG R S SGG G GS GG G + GGS S GSGGG G
Sbjct: 16 GSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLG---STLGGSSYSSCYSFGSGGGYGSS 72
Query: 534 YGGGSG 539
+GG G
Sbjct: 73 FGGVDG 78
Score = 38.1 bits (87), Expect = 0.024
Identities = 35/89 (39%), Positives = 39/89 (43%), Gaps = 26/89 (29%)
Query: 2 SCRQF--SSSYLSRSGGGGG---------GGLGSGGSIRSSYSRFSSSGGGGGGGRFSSS 50
S RQF SSS SG GGG GGLG+G R S+GG G
Sbjct: 4 SIRQFTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGS------CRLGSAGGLG-------- 49
Query: 51 SGYGGGSSRVC-GRGGGGSFGYSYGGGSG 78
S GG S C G GG +G S+GG G
Sbjct: 50 STLGGSSYSSCYSFGSGGGYGSSFGGVDG 78
Score = 36.2 bits (82), Expect = 0.093
Identities = 32/74 (43%), Positives = 33/74 (44%), Gaps = 5/74 (6%)
Query: 467 SSGAGKIGLGGRGGSGGSYGRGSRGGSGGSY---GGGGSGGGYGGGSGSRGGSGGSYGGG 523
SS G GLGG GS + R S G GS GG G GG S S S GS GG
Sbjct: 12 SSIKGSSGLGG--GSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGY 69
Query: 524 SGSGGGSGGGYGGG 537
S GG G GG
Sbjct: 70 GSSFGGVDGLLAGG 83
Score = 35.8 bits (81), Expect = 0.12
Identities = 33/80 (41%), Positives = 37/80 (46%), Gaps = 12/80 (15%)
Query: 502 SGGGYGGGSGSRGGSGGS---YGGGSGSGG---GSGGGYGGGSGGGHSGGSGGGHSGGSG 555
S G SG GGS + GG G+G GS GG G + GG S S +S GSG
Sbjct: 10 SSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGS-TLGGSSYSS--CYSFGSG 66
Query: 556 GNYGGGSGSGGGSGGGYGGG 575
G YG S GG G GG
Sbjct: 67 GGYG---SSFGGVDGLLAGG 83
Score = 32.7 bits (73), Expect = 1.0
Identities = 20/48 (41%), Positives = 21/48 (43%)
Query: 576 SGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSSHS 623
S S GS G GG S G G G GS GG G G SS+S
Sbjct: 11 SSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYS 58
Score = 29.6 bits (65), Expect = 8.7
Identities = 22/48 (45%), Positives = 24/48 (50%), Gaps = 10/48 (20%)
Query: 17 GGGGGLGS--GGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCG 62
G GGLGS GG SSYS S G GGG G S +GG + G
Sbjct: 43 GSAGGLGSTLGG---SSYSSCYSFGSGGGYG-----SSFGGVDGLLAG 82
>gi|24234699 keratin 19 [Homo sapiens]
Length = 400
Score = 369 bits (947), Expect = e-102
Identities = 206/393 (52%), Positives = 264/393 (67%), Gaps = 4/393 (1%)
Query: 82 SASSLGGGFGGGSRGFG-GASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGG 140
SA+S GG GGGS FG G + S GG GG S F SG G GG+GG
Sbjct: 10 SATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYG-GGYGGV 68
Query: 141 AGGGDGGILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKN 200
DG +L NEK TMQ LN RLASYLDKV+ALE AN +LE KI+DWY K+GP ++
Sbjct: 69 LTASDG-LLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGP-SRD 126
Query: 201 YSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGL 260
YS YY TI DL+D+I+ T+ N++ +L IDN R+ DDFR KFE EQ LR V+ADINGL
Sbjct: 127 YSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGL 186
Query: 261 RQVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLT 320
R+VLD LT+ ++DLEMQ E L+EEL LKKNH+EE+S L GQ G V+VE++ APG DL
Sbjct: 187 RRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLA 246
Query: 321 KTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQEL 380
K L+DMR +YE + +NRKD E + ++ ++ EV+ +++Q S EVT LR +Q L
Sbjct: 247 KILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGL 306
Query: 381 EIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLL 440
EIELQSQLS KAALE +L +T+ R+ QL IQ IS +EAQ+ DVR + E QNQEY L
Sbjct: 307 EIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRL 366
Query: 441 LSIKMRLEKEIETYHNLLEGGQEDFESSGAGKI 473
+ IK RLE+EI TY +LLEG ++ + + A K+
Sbjct: 367 MDIKSRLEQEIATYRSLLEGQEDHYNNLSASKV 399
Score = 36.2 bits (82), Expect = 0.093
Identities = 25/67 (37%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query: 502 SGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGG 561
S GG GGGS R G G ++ S GG G G S S S G + GG GG
Sbjct: 14 SFGGLGGGS-VRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGGYGGVLTAS 72
Query: 562 SGSGGGS 568
G G+
Sbjct: 73 DGLLAGN 79
Score = 34.7 bits (78), Expect = 0.27
Identities = 24/64 (37%), Positives = 25/64 (39%), Gaps = 5/64 (7%)
Query: 519 SYGGGSGSGGGSGGGYGGGS-----GGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYG 573
SY S S GG GGGS G S G SGG G + S G YG
Sbjct: 3 SYSYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYG 62
Query: 574 GGSG 577
GG G
Sbjct: 63 GGYG 66
Score = 33.9 bits (76), Expect = 0.46
Identities = 30/80 (37%), Positives = 36/80 (45%), Gaps = 12/80 (15%)
Query: 7 SSSYLSRSGGGGGGGLGSGGSIR--SSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRG 64
S SY S GGLG GGS+R + + S GG GGR G S+R
Sbjct: 3 SYSYRQSSATSSFGGLG-GGSVRFGPGVAFRAPSIHGGSGGR-----GVSVSSARFVSSS 56
Query: 65 GGGSFGYSYGGGSGGGFSAS 84
G +YGGG GG +AS
Sbjct: 57 SSG----AYGGGYGGVLTAS 72
Score = 32.3 bits (72), Expect = 1.3
Identities = 24/72 (33%), Positives = 28/72 (38%), Gaps = 2/72 (2%)
Query: 484 SYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHS 543
SY + S S G GGG G G + GGS GG G S S G +
Sbjct: 5 SYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGS--GGRGVSVSSARFVSSSSSGAYG 62
Query: 544 GGSGGGHSGGSG 555
GG GG + G
Sbjct: 63 GGYGGVLTASDG 74
Score = 32.0 bits (71), Expect = 1.7
Identities = 24/65 (36%), Positives = 27/65 (41%), Gaps = 4/65 (6%)
Query: 557 NYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEE---ASGSGGGY 613
+Y S S GG GGGS R G G + S GG G +S S G Y
Sbjct: 3 SYSYRQSSATSSFGGLGGGS-VRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAY 61
Query: 614 GGGSG 618
GGG G
Sbjct: 62 GGGYG 66
Score = 30.8 bits (68), Expect = 3.9
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 1/51 (1%)
Query: 476 GGRGGSGGSYGRGSRGGSGGSYGG-GGSGGGYGGGSGSRGGSGGSYGGGSG 525
GG GG +G G + +GG GG G S G+YGGG G
Sbjct: 16 GGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGGYG 66
Score = 29.6 bits (65), Expect = 8.7
Identities = 25/76 (32%), Positives = 28/76 (36%), Gaps = 4/76 (5%)
Query: 534 YGGGSGGGHSGGSGGGHSG-GSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGF 592
Y S GG GGG G G + S GG G G S S S G G+
Sbjct: 6 YRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGGY 65
Query: 593 GG---ESGGSYGGGEE 605
GG S G G E+
Sbjct: 66 GGVLTASDGLLAGNEK 81
>gi|153945736 keratin 27 [Homo sapiens]
Length = 459
Score = 342 bits (877), Expect = 6e-94
Identities = 195/409 (47%), Positives = 249/409 (60%), Gaps = 23/409 (5%)
Query: 90 FGGGSRGFGGASGGGYSSSGGFGGGFGGGSG---GGFGGGYGSGFGGF---GGFGGGAGG 143
F SR G G G G GFG G+ G G G+ FGG GG+GGG GG
Sbjct: 5 FSSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLGG 64
Query: 144 GDG----------GILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKG 193
G G+L+ NEK TMQ LN RLASYL+ V+ALEEAN DLE KI+ WY+K G
Sbjct: 65 GSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKFG 124
Query: 194 PAA---IQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLR 250
P + + +YS Y+ ID+LK+QI+ T N +L DN R+T DDFR+KFE E L
Sbjct: 125 PGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELALH 184
Query: 251 QGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVE 310
Q V+ADINGLR+VLD LT+ ++DLE+Q ETL EEL LKKNH+EEM L G+VNVE
Sbjct: 185 QSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNVE 244
Query: 311 INVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEV 370
+N APG DLT LN+MR EYE L +NR+D E + + ++ ++S S+ E+
Sbjct: 245 MNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNEL 304
Query: 371 TQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEI 430
+++ +Q LEIELQS L+ K +LE SL +T++ YC QL IQ QI LE Q+ VR E
Sbjct: 305 IEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTET 364
Query: 431 ECQNQEYSLLLSIKMRLEKEIETYHNLLEGGQEDFESSGAGKIGLGGRG 479
E Q EY LL IK+ LEKEIETY L++G + S + G GG G
Sbjct: 365 EGQKLEYEQLLDIKVHLEKEIETYCLLIDGE----DGSCSKSKGYGGPG 409
Score = 45.8 bits (107), Expect = 1e-04
Identities = 32/70 (45%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 525 GSGGGSGGGYGGGSGGGHSGGSGGGHSG-GSGGNYG-GGSGSGGGSGGGYGGGSGSRGG- 581
GS GG+G G G G+ G G GSG + GGS S GG GGG GGGS S
Sbjct: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLGGGSASCAAF 72
Query: 582 SGGSHGGGSG 591
+G HG SG
Sbjct: 73 TGNEHGLLSG 82
Score = 44.3 bits (103), Expect = 3e-04
Identities = 29/54 (53%), Positives = 31/54 (57%), Gaps = 3/54 (5%)
Query: 488 GSRGGSGG-SYGGGGSGGGYGGGSGSRG-GSGGSYG-GGSGSGGGSGGGYGGGS 538
GS GG+G GG+G G G G G GSG S GGS S GG GGG GGGS
Sbjct: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLGGGS 66
Score = 43.1 bits (100), Expect = 8e-04
Identities = 27/58 (46%), Positives = 33/58 (56%), Gaps = 7/58 (12%)
Query: 560 GGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGS 617
GG+GS S GG G G+G+ + G G GSGF ++GG A G GGG GGGS
Sbjct: 16 GGTGSVRLSSGGAGFGAGN---TCGVPGIGSGF----SCAFGGSSSAGGYGGGLGGGS 66
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/85 (40%), Positives = 40/85 (47%), Gaps = 15/85 (17%)
Query: 475 LGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGY 534
LG GG+G R S GG+G +G G + G G GSG GGS S GGY
Sbjct: 12 LGSCGGTGSV--RLSSGGAG--FGAGNTCGVPGIGSGFSCAFGGS---------SSAGGY 58
Query: 535 GGGSGGGHSGGSG--GGHSGGSGGN 557
GGG GGG + + G G GN
Sbjct: 59 GGGLGGGSASCAAFTGNEHGLLSGN 83
Score = 41.6 bits (96), Expect = 0.002
Identities = 28/76 (36%), Positives = 33/76 (43%), Gaps = 5/76 (6%)
Query: 536 GGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGS----G 591
G GG S G +G GN G G G G +GG S + GG GG GGGS
Sbjct: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSA-GGYGGGLGGGSASCAA 71
Query: 592 FGGESGGSYGGGEEAS 607
F G G G E+ +
Sbjct: 72 FTGNEHGLLSGNEKVT 87
Score = 40.8 bits (94), Expect = 0.004
Identities = 28/66 (42%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
Query: 511 GSRGGSGGSYGGGSGSGGGSGGGYG-GGSGGGHSGGSGGGHS-GGSGGNYGGGSGSGGGS 568
GS GG+G G+G G+G G G G G S GG S GG GG GGGS S
Sbjct: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLGGGSASCAAF 72
Query: 569 GGGYGG 574
G G
Sbjct: 73 TGNEHG 78
Score = 37.7 bits (86), Expect = 0.032
Identities = 29/79 (36%), Positives = 38/79 (48%), Gaps = 9/79 (11%)
Query: 501 GSGGGYGGGSGSRGGSGGSYGGGSGSG-GGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYG 559
GS GG G S GG+G +G G+ G G G G+ GG S GG+ GG G G
Sbjct: 13 GSCGGTGSVRLSSGGAG--FGAGNTCGVPGIGSGFSCAFGGS---SSAGGYGGGLG---G 64
Query: 560 GGSGSGGGSGGGYGGGSGS 578
G + +G +G SG+
Sbjct: 65 GSASCAAFTGNEHGLLSGN 83
Score = 37.4 bits (85), Expect = 0.042
Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 10/76 (13%)
Query: 469 GAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGG 528
G G + L GG+G +G G+ G G G G +GG S S G YGGG G G
Sbjct: 17 GTGSVRLSS-GGAG--FGAGNTCGVPGI--GSGFSCAFGGSS-----SAGGYGGGLGGGS 66
Query: 529 GSGGGYGGGSGGGHSG 544
S + G G SG
Sbjct: 67 ASCAAFTGNEHGLLSG 82
Score = 36.2 bits (82), Expect = 0.093
Identities = 27/66 (40%), Positives = 29/66 (43%), Gaps = 3/66 (4%)
Query: 553 GSGGNYGGGSGSGGGSGGGYGGGSGSRG-GSGGS--HGGGSGFGGESGGSYGGGEEASGS 609
GS G G S GG+G G G G G GSG S GG S GG GG GG +
Sbjct: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLGGGSASCAAF 72
Query: 610 GGGYGG 615
G G
Sbjct: 73 TGNEHG 78
Score = 35.0 bits (79), Expect = 0.21
Identities = 29/73 (39%), Positives = 36/73 (49%), Gaps = 6/73 (8%)
Query: 549 GHSGGSGGNY--GGGSGSGGGSGGGYGG-GSGSRGGSGGSHGGGSGFGGESGGSYGGGEE 605
G GG+G GG+G G G+ G G GSG GGS G G+GG GG G
Sbjct: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAG-GYGGGLGG--GSASC 69
Query: 606 ASGSGGGYGGGSG 618
A+ +G +G SG
Sbjct: 70 AAFTGNEHGLLSG 82
Score = 30.4 bits (67), Expect = 5.1
Identities = 24/61 (39%), Positives = 27/61 (44%), Gaps = 2/61 (3%)
Query: 467 SSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGG-SGGSYGGGSG 525
SSG G G G G S G S G G GGG GGGS S +G +G SG
Sbjct: 24 SSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAG-GYGGGLGGGSASCAAFTGNEHGLLSG 82
Query: 526 S 526
+
Sbjct: 83 N 83
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 340 bits (872), Expect = 2e-93
Identities = 230/658 (34%), Positives = 341/658 (51%), Gaps = 74/658 (11%)
Query: 4 RQFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGG----GGGGGRFSSSSGYGG---- 55
RQFSS RSG GGG SG + +Y R ++S GGGGGRFSS G GG
Sbjct: 3 RQFSS----RSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGA 58
Query: 56 ----GSSRVCGRGGGGSFGYSY--GGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSG 109
GS + GG S S GGG G GF GGG+GGG G GG GGG+ G
Sbjct: 59 GGGFGSRSLVNLGGSKSISISVARGGGRGSGF-----GGGYGGGGFGGGGFGGGGFGGGG 113
Query: 110 GFGGGFGG--GSGGGFGGGYGSGFGGFGGFGGGAGG--GDGGI----------------- 148
GGGFGG GGGFGGG GFGG GG+GGG G GGI
Sbjct: 114 IGGGGFGGFGSGGGGFGGG---GFGG-GGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEI 169
Query: 149 ------LTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYS 202
+ + E+ ++ LN++ AS++DKV+ LE+ N L+ K + + + N
Sbjct: 170 DPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTK-WELLQQVDTSTRTHNLE 228
Query: 203 PYYNT-IDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLR 261
PY+ + I++L+ ++ L ++ ++ N + ++D+R K+E E N R + + ++
Sbjct: 229 PYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIK 288
Query: 262 QVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGK--DL 319
+ +D M K DL+ + + LQ+E+ L ++ E+SQ+ Q S + NV +++ + DL
Sbjct: 289 KDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQIS-ETNVILSMDNNRSLDL 347
Query: 320 TKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQE 379
+ +++ +YE + K++ + E+ Y+++ +++ G V++S E+++L +Q
Sbjct: 348 DSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQR 407
Query: 380 LEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSL 439
L E+ + + + L++S+ D + R L+ + ++++LE + ++++ ++Y
Sbjct: 408 LRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQE 467
Query: 440 LLSIKMRLEKEIETYHNLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGG 499
L++ K+ L+ EI TY LLEG + A + + G GSRGG GG YG
Sbjct: 468 LMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGS 527
Query: 500 GGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYG 559
GGS G GGGS GSGG GGG GS G G YG G G SGG GGGH G+YG
Sbjct: 528 GGSSYGSGGGS---YGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGH-----GSYG 579
Query: 560 GGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGS 617
GS S GGY GGSG GG GGS GG GG SGGS GG +SG GG S
Sbjct: 580 SGS-----SSGGYRGGSG--GGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSS 630
Score = 72.4 bits (176), Expect = 1e-12
Identities = 36/63 (57%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Query: 561 GSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGG-YGGGSGK 619
G GS GG GGGYG G S G GGS+G G G GG GSYG G + GSGGG YG G G
Sbjct: 514 GGGSRGGGGGGYGSGGSSYGSGGGSYGSGGG-GGGGRGSYGSGGSSYGSGGGSYGSGGGG 572
Query: 620 SSH 622
H
Sbjct: 573 GGH 575
Score = 72.0 bits (175), Expect = 2e-12
Identities = 40/76 (52%), Positives = 42/76 (55%), Gaps = 4/76 (5%)
Query: 550 HSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGS 609
H+ SGG GG G G GSGG G G GSGG GGG G G G SYG G + GS
Sbjct: 509 HTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGS 568
Query: 610 GGGYGG----GSGKSS 621
GGG GG GSG SS
Sbjct: 569 GGGGGGHGSYGSGSSS 584
Score = 35.0 bits (79), Expect = 0.21
Identities = 24/62 (38%), Positives = 26/62 (41%), Gaps = 2/62 (3%)
Query: 562 SGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSS 621
S SG SGGG+ SGS G S SGG G G GG +G G G S
Sbjct: 7 SRSGYRSGGGFS--SGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGS 64
Query: 622 HS 623
S
Sbjct: 65 RS 66
Score = 32.7 bits (73), Expect = 1.0
Identities = 24/58 (41%), Positives = 27/58 (46%), Gaps = 10/58 (17%)
Query: 7 SSSYLSRSGGGGGGGLG--------SGGSI--RSSYSRFSSSGGGGGGGRFSSSSGYG 54
S Y SGGGGGG G SGGSI R S S S GG +F S++ G
Sbjct: 584 SGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYSG 641
>gi|114431246 keratin 25D [Homo sapiens]
Length = 464
Score = 340 bits (871), Expect = 3e-93
Identities = 196/423 (46%), Positives = 256/423 (60%), Gaps = 23/423 (5%)
Query: 53 YGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFG 112
+ GS VC R G GS GG GF+ SS GG GS F A GGG S G
Sbjct: 5 FSNGSRHVCLRSGAGSVRPLNGGA---GFAGSSACGGSVAGSE-FSCALGGGLGSVPG-- 58
Query: 113 GGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRLASYLDKVQ 172
G +GG G GF G +GG+L+ NEK TMQ LN RLASYLD V+
Sbjct: 59 ---GSHAGGALGNAACIGFAG----------SEGGLLSGNEKVTMQNLNDRLASYLDNVR 105
Query: 173 ALEEANNDLENKIQDWYDKKGPAA---IQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDI 229
ALEEAN +LE KI+ WY+K GP + + +YS Y+ TI+DLK++I+ T N +L I
Sbjct: 106 ALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQI 165
Query: 230 DNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALK 289
DN R+ DDFR+K+E E L Q V+ADINGLR+VLD LT+ ++D E+QYE+L EE+ LK
Sbjct: 166 DNARLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLK 225
Query: 290 KNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQI 349
KNH+EEM L G+VNVE+N APG DL LN+MR EYE L +NRKD E + +
Sbjct: 226 KNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKS 285
Query: 350 TQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQL 409
++ ++S + ++T++R +Q LEI+LQS ++ K +LE SL +T++ YC QL
Sbjct: 286 ASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQL 345
Query: 410 QMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEG-GQEDFESS 468
IQ QI LE Q+ VR E E Q EY LL +K+ LEKEIETY L++G G +S
Sbjct: 346 AQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSK 405
Query: 469 GAG 471
G G
Sbjct: 406 GFG 408
Score = 40.8 bits (94), Expect = 0.004
Identities = 29/77 (37%), Positives = 36/77 (46%), Gaps = 10/77 (12%)
Query: 538 SGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGS------- 590
SG G GG +G +G + GGS +G GGG GS GGSH GG+
Sbjct: 16 SGAGSVRPLNGG-AGFAGSSACGGSVAGSEFSCALGGGLGSV--PGGSHAGGALGNAACI 72
Query: 591 GFGGESGGSYGGGEEAS 607
GF G GG G E+ +
Sbjct: 73 GFAGSEGGLLSGNEKVT 89
Score = 39.7 bits (91), Expect = 0.008
Identities = 28/69 (40%), Positives = 32/69 (46%), Gaps = 8/69 (11%)
Query: 499 GGGSGGGYGGGSGSRGGS--GGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGG-----GHS 551
G GS GG+G G S GGS G S GGG G GG H+GG+ G G +
Sbjct: 17 GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCA-LGGGLGSVPGGSHAGGALGNAACIGFA 75
Query: 552 GGSGGNYGG 560
G GG G
Sbjct: 76 GSEGGLLSG 84
Score = 38.9 bits (89), Expect = 0.014
Identities = 24/64 (37%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 507 GGGSGSRGGSGGSYGGGSGSGGG-SGGGYGGGSGGGHSGGSGGGHSGGSGGNYG--GGSG 563
G GS G + G S GG +G + GGG GG H+GG+ GN G +G
Sbjct: 17 GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAG 76
Query: 564 SGGG 567
S GG
Sbjct: 77 SEGG 80
Score = 36.6 bits (83), Expect = 0.071
Identities = 24/64 (37%), Positives = 29/64 (45%), Gaps = 9/64 (14%)
Query: 564 SGGGSGGGYGGGSGSRGGS--GGSHGG-------GSGFGGESGGSYGGGEEASGSGGGYG 614
SG GS GG+G G S GGS G G G G GGS+ GG + + G+
Sbjct: 16 SGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFA 75
Query: 615 GGSG 618
G G
Sbjct: 76 GSEG 79
Score = 36.2 bits (82), Expect = 0.093
Identities = 30/78 (38%), Positives = 35/78 (44%), Gaps = 10/78 (12%)
Query: 468 SGAGKIG-LGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGS 526
SGAG + L G G GS GGS G GGG GS GGS+ GG+
Sbjct: 16 SGAGSVRPLNGGAGFAGS------SACGGSVAGSEFSCALGGGLGS--VPGGSHAGGA-L 66
Query: 527 GGGSGGGYGGGSGGGHSG 544
G + G+ G GG SG
Sbjct: 67 GNAACIGFAGSEGGLLSG 84
Score = 35.0 bits (79), Expect = 0.21
Identities = 26/65 (40%), Positives = 30/65 (46%), Gaps = 2/65 (3%)
Query: 526 SGGGSGGGYGGGSGGGHSGGSGGGHSGGSGG-NYGGGSGS-GGGSGGGYGGGSGSRGGSG 583
SG GS GG+G S GG +G GGG GS GGS G G+ + G
Sbjct: 16 SGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFA 75
Query: 584 GSHGG 588
GS GG
Sbjct: 76 GSEGG 80
Score = 34.3 bits (77), Expect = 0.35
Identities = 25/69 (36%), Positives = 28/69 (40%), Gaps = 5/69 (7%)
Query: 489 SRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGG-----GHS 543
S GS GG G GS GS S G G G GG + GG+ G G +
Sbjct: 16 SGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFA 75
Query: 544 GGSGGGHSG 552
G GG SG
Sbjct: 76 GSEGGLLSG 84
Score = 33.5 bits (75), Expect = 0.60
Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 2/66 (3%)
Query: 512 SRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGG 571
S GS GG+G G S G G +G S GGG GG++ GG+ G + G
Sbjct: 16 SGAGSVRPLNGGAGFAGSSACG-GSVAGSEFSCALGGGLGSVPGGSHAGGA-LGNAACIG 73
Query: 572 YGGGSG 577
+ G G
Sbjct: 74 FAGSEG 79
Score = 32.7 bits (73), Expect = 1.0
Identities = 20/46 (43%), Positives = 23/46 (50%), Gaps = 4/46 (8%)
Query: 579 RGGSGGSH--GGGSGFGGES--GGSYGGGEEASGSGGGYGGGSGKS 620
R G+G GG+GF G S GGS G E + GGG G G S
Sbjct: 15 RSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGS 60
Score = 31.6 bits (70), Expect = 2.3
Identities = 26/75 (34%), Positives = 32/75 (42%), Gaps = 4/75 (5%)
Query: 545 GSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGE 604
G+G G + G S GG G S + GG GS GGS GG G + G
Sbjct: 17 GAGSVRPLNGGAGFAGSSACGGSVAGSEF--SCALGGGLGSVPGGSHAGGALGNAACIG- 73
Query: 605 EASGSGGGYGGGSGK 619
+GS GG G+ K
Sbjct: 74 -FAGSEGGLLSGNEK 87
Score = 31.2 bits (69), Expect = 3.0
Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
Query: 467 SSGAGKIGLGGRGGS-GGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSG 525
+ GAG G GGS GS + GG GS GG GG G + G +G G SG
Sbjct: 25 NGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAGSEGGLLSG 84
Query: 526 S 526
+
Sbjct: 85 N 85
>gi|31559829 keratin 25 [Homo sapiens]
Length = 450
Score = 339 bits (870), Expect = 4e-93
Identities = 195/395 (49%), Positives = 246/395 (62%), Gaps = 13/395 (3%)
Query: 92 GGSRGFGGASGGGYSSSG-GFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILT 150
GG FG + G S G GF FGG S GG GG G+ GF + G+L+
Sbjct: 25 GGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGG-GNPCAGFTV-------NERGLLS 76
Query: 151 ANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAA---IQKNYSPYYNT 207
NEK TMQ LN RLASYLD V ALEEAN DLE KI+ WY+K GP + + +YS Y+
Sbjct: 77 GNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPI 136
Query: 208 IDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNL 267
IDDLK+QI+ T N +L IDN R+T DDFR+K+E E L Q V+AD+NGLR+VLD +
Sbjct: 137 IDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVLDEI 196
Query: 268 TMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMR 327
T+ ++DLE+QYETL EE+ LKKNHKEEM L G+VNVE+N APG DLT LN+MR
Sbjct: 197 TLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLNNMR 256
Query: 328 QEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQ 387
EYE L +NR+D E + + ++ ++S S+ E+T+++ +Q LEIELQS
Sbjct: 257 AEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIELQSL 316
Query: 388 LSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRL 447
L+ K +LE SL +T++ YC QL IQ QI LE Q+ VR E E Q EY LL IK+ L
Sbjct: 317 LATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKLHL 376
Query: 448 EKEIETYHNLLEGGQEDFESSGAGKIGLGGRGGSG 482
EKEIETY LL GG + SG K G G G
Sbjct: 377 EKEIETY-CLLIGGDDGACKSGGYKSKDYGSGNVG 410
Score = 37.4 bits (85), Expect = 0.042
Identities = 22/53 (41%), Positives = 25/53 (47%)
Query: 492 GSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSG 544
G G S+G G S G G GSG GGS GG+ GG G+ G SG
Sbjct: 25 GGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGGGNPCAGFTVNERGLLSG 77
Score = 37.0 bits (84), Expect = 0.054
Identities = 23/52 (44%), Positives = 26/52 (50%), Gaps = 4/52 (7%)
Query: 515 GSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGG 566
GS YGGG+ G G+ G G G G S GG SGGN GGG+ G
Sbjct: 19 GSLRLYGGGTSFGTGNSCGI-SGIGSGFSSAFGG---SSSGGNTGGGNPCAG 66
Score = 35.8 bits (81), Expect = 0.12
Identities = 23/59 (38%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 553 GSGGNYGGGSGSGGGSGGGYGG-GSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSG 610
GS YGGG+ G G+ G G GSG GGS GG+ GG + E SG
Sbjct: 19 GSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGGGNPCAGFTVNERGLLSG 77
Score = 35.8 bits (81), Expect = 0.12
Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
Query: 480 GSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGG 528
GS YG G+ G+G S G G G G+ G SGG+ GGG+ G
Sbjct: 19 GSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGG-SSSGGNTGGGNPCAG 66
Score = 34.3 bits (77), Expect = 0.35
Identities = 23/61 (37%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
Query: 547 GGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEA 606
GGG S G+G N G SG G G +GG S GG+ G +GF G G E+
Sbjct: 25 GGGTSFGTG-NSCGISGIGSGFSSAFGGSSS--GGNTGGGNPCAGFTVNERGLLSGNEKV 81
Query: 607 S 607
+
Sbjct: 82 T 82
Score = 33.5 bits (75), Expect = 0.60
Identities = 82/413 (19%), Positives = 153/413 (37%), Gaps = 58/413 (14%)
Query: 2 SCRQFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVC 61
SC + ++ L GGG G G+ I S FSS+ GG SSSG G C
Sbjct: 12 SCPRPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGG-------SSSGGNTGGGNPC 64
Query: 62 GRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGG 121
G G + + + A+ G+ FG GS
Sbjct: 65 AGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCR 124
Query: 122 GFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRLASYLDKVQALEEANNDL 181
G Y F T+N + +Q N+RL + ++
Sbjct: 125 GLDHDYSRYFPIIDDLKNQIIAS----TTSNANAVLQIDNARLTA--------DDFRLKY 172
Query: 182 ENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRI 241
EN++ A+ ++ N + + D+I +T L+I ++ + +
Sbjct: 173 ENEL----------ALHQSVEADVNGLRRVLDEITLC-----RTDLEIQYETLSEEMTYL 217
Query: 242 KFEMEQNLR-------QGVDADINGLRQVLDNLTMEKSDLEMQYETLQEE-LMALKKNHK 293
K ++ ++ V+ ++N V +LT+ +++ +YE L E+ +
Sbjct: 218 KKNHKEEMQVLQCAAGGNVNVEMNAAPGV--DLTVLLNNMRAEYEALAEQNRRDAEAWFN 275
Query: 294 EEMSQLTGQNSGDVNVEINVAPG-KDLTKTLNDMRQEYEQLIAKNRK------DIENQYE 346
E+ + L Q S DV + ++ +TL + E + L+A + E+ Y
Sbjct: 276 EKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYC 335
Query: 347 TQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLE 399
Q+ QI+ ++ + +++ Q+R + ++E + L K LEK +E
Sbjct: 336 AQLAQIQAQIGALEEQLH-------QVRTETEGQKLEYEQLLDIKLHLEKEIE 381
Score = 33.5 bits (75), Expect = 0.60
Identities = 21/40 (52%), Positives = 24/40 (60%), Gaps = 4/40 (10%)
Query: 534 YGGGS--GGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGG 571
YGGG+ G G+S G G SG S GGS SGG +GGG
Sbjct: 24 YGGGTSFGTGNSCGISGIGSGFSSAF--GGSSSGGNTGGG 61
Score = 32.0 bits (71), Expect = 1.7
Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 6/45 (13%)
Query: 506 YGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGH 550
YGGG+ G+G S G SG G G +GG S GG +GGG+
Sbjct: 24 YGGGTSF--GTGNSCGI-SGIGSGFSSAFGGSSSGG---NTGGGN 62
Score = 32.0 bits (71), Expect = 1.7
Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Query: 477 GRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGS 526
G G S G G GS G ++GG SGG GGG+ G + G SG+
Sbjct: 31 GTGNSCGISGIGS--GFSSAFGGSSSGGNTGGGNPCAGFTVNERGLLSGN 78
>gi|31559815 keratin 26 [Homo sapiens]
Length = 468
Score = 317 bits (813), Expect = 2e-86
Identities = 186/417 (44%), Positives = 249/417 (59%), Gaps = 25/417 (5%)
Query: 55 GGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGG 114
GGS R+C R G G G G GF A ++ G G+R + G SS G F
Sbjct: 7 GGSRRICSRTGSGRLS-----GGGTGFVAGNVC--VGSGARSSFSCTLEGISSGGSFCN- 58
Query: 115 FGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRLASYLDKVQAL 174
SGGG G G +GF G + +L+ NEK TMQ LN RLASYLD V AL
Sbjct: 59 ----SGGGLGSGACAGFLG----------NEHSLLSGNEKVTMQNLNDRLASYLDHVHAL 104
Query: 175 EEANNDLENKIQDWYDKKGPAAIQKN---YSPYYNTIDDLKDQIVDLTVGNNKTLLDIDN 231
EEAN DLE KI+ Y+K P + +++ YS Y++ I+DLK QI T+ N +L DN
Sbjct: 105 EEANADLEQKIKGRYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDN 164
Query: 232 TRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKN 291
R+T DDFR+K+E E L V+AD +GLR+VLD LT+ +DLE+Q ETL EEL LKK+
Sbjct: 165 ARLTADDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKS 224
Query: 292 HKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQ 351
H+EEM L G+VNVE+N PG DLT LN+MR EYE L +NRKD E + +
Sbjct: 225 HEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSAT 284
Query: 352 IEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQM 411
++ ++S ++ E+T+L+ +Q LEIELQS ++ K + E SL +T+ YC QLQ
Sbjct: 285 LQQQISDHEGAATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQ 344
Query: 412 IQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEGGQEDFESS 468
IQ+QI +E Q+ +R E E Q EY LL +K+ LEKEI+ Y NLL+G + +S+
Sbjct: 345 IQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKST 401
Score = 37.4 bits (85), Expect = 0.042
Identities = 26/58 (44%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Query: 512 SRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSG 569
SR GSG GGG+G G+ G G+ S G SGGS N GGG GSG +G
Sbjct: 14 SRTGSGRLSGGGTGFVAGNVC-VGSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAG 70
Score = 35.8 bits (81), Expect = 0.12
Identities = 31/79 (39%), Positives = 33/79 (41%), Gaps = 4/79 (5%)
Query: 481 SGGSYGRGSRGGSGGSYGGGGS--GGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGS 538
SGGS SR GSG GGG G GSG+R + G S GGS GGG
Sbjct: 6 SGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISS--GGSFCNSGGGL 63
Query: 539 GGGHSGGSGGGHSGGSGGN 557
G G G G GN
Sbjct: 64 GSGACAGFLGNEHSLLSGN 82
Score = 30.0 bits (66), Expect = 6.6
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 6/66 (9%)
Query: 458 LEGGQEDFES-SGAGKIGLGGRGGSGGS--YGRGSRGGSGGSYGGGGSGGGY---GGGSG 511
L GG S +G+G++ GG G G+ G G+R + G SGG + GGG G
Sbjct: 5 LSGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLG 64
Query: 512 SRGGSG 517
S +G
Sbjct: 65 SGACAG 70
Score = 30.0 bits (66), Expect = 6.6
Identities = 22/69 (31%), Positives = 27/69 (39%), Gaps = 4/69 (5%)
Query: 543 SGGSGGGHSGGSGGNYGGGSGSGGGSG----GGYGGGSGSRGGSGGSHGGGSGFGGESGG 598
SG GG +G GN GSG+ G GGS G G G +GF G
Sbjct: 18 SGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHS 77
Query: 599 SYGGGEEAS 607
G E+ +
Sbjct: 78 LLSGNEKVT 86
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 313 bits (802), Expect = 3e-85
Identities = 228/653 (34%), Positives = 329/653 (50%), Gaps = 78/653 (11%)
Query: 1 MSCRQFSSSYLSRSGGGGG-------GGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGY 53
MSC Q S R GGGGG + SGGS RS+ S S GGGGG F G
Sbjct: 1 MSC-QISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFG---GG 56
Query: 54 GGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGAS----GGGYSSSG 109
G GS + G GG S S GG GGGF A+ GGFGG GFGG S G G+S G
Sbjct: 57 GFGSRSLVGLGGTKSISISVAGG-GGGFGAA---GGFGGRGGGFGGGSSFGGGSGFSGGG 112
Query: 110 GFGGGFGGGSGGGFGGGYGSGFGGFGGFGG-GAGGGDGGI-------------------- 148
GGGFGGG GGFGG G GG GG GG G GG GGI
Sbjct: 113 FGGGGFGGGRFGGFGGP--GGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPE 170
Query: 149 ---LTANEKSTMQELNSRLASYLDKVQALEEANNDLENK---IQDWYDKKGPAAIQKNYS 202
+ A E+ ++ LN++ AS++DKV+ LE+ N L+ K +Q P ++ +
Sbjct: 171 IQNVKAQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQ 230
Query: 203 PYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQ 262
Y ID LK + LT +++N + ++D++ K+E E N R + D L++
Sbjct: 231 GY---IDSLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKK 287
Query: 263 VLDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGK--DLT 320
+DN M K +L+ + + L +E+ LK + E+SQ+ Q+ D NV +++ + DL
Sbjct: 288 DVDNAYMIKVELQSKVDLLNQEIEFLKVLYDAEISQIH-QSVTDTNVILSMDNSRNLDLD 346
Query: 321 KTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQEL 380
+ +++ +YE++ +++++ E Y ++ +++ V G ++ E+++L +Q L
Sbjct: 347 SIIAEVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRL 406
Query: 381 EIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLL 440
+ E+ + ++ ++ D + R L+ + ++++LE + ++++ ++Y L
Sbjct: 407 QGEIAHVKKQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQEL 466
Query: 441 LSIKMRLEKEIETYHNLLEGGQ-----------------EDFESSGAGKIGLGGRGGSGG 483
+++K+ L+ EI TY LLEG + S+ A K GG GG G
Sbjct: 467 MNVKLALDVEIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGS 526
Query: 484 SYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGG-SGGSYGGGSGSGG--GSGGGYGGGSGG 540
S G G GS SYG GG G GGSG G SGG YG G GSGG GSGGG GGS
Sbjct: 527 SSGGGYSSGSS-SYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSIS 585
Query: 541 GHSGGSGGG-HSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGF 592
G GSGGG HS SGG GGS SGGG G G GG S +G SG + G F
Sbjct: 586 GGGYGSGGGKHS--SGGGSRGGSSSGGGYGSGGGGSSSVKGSSGEAFGSSVTF 636
Score = 95.1 bits (235), Expect = 2e-19
Identities = 65/137 (47%), Positives = 70/137 (51%), Gaps = 15/137 (10%)
Query: 496 SYGGGGSGGGYGG-GSGSRGGSGGSYGGGSGSG-----GGSGGGYGGGSGGGHS-GGSGG 548
S G GG GGG+ G SGS SGGS S GG GGG+GGG G S G GG
Sbjct: 9 SRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGG 68
Query: 549 GHS-----GGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHG--GGSGFGGESGGSYG 601
S G GG +G G GG GGG+GGGS GGSG S G GG GFGG G +G
Sbjct: 69 TKSISISVAGGGGGFGAAGGFGG-RGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFG 127
Query: 602 GGEEASGSGGGYGGGSG 618
G G GG G G G
Sbjct: 128 GPGGVGGLGGPGGFGPG 144
Score = 86.3 bits (212), Expect = 8e-17
Identities = 58/130 (44%), Positives = 60/130 (46%), Gaps = 10/130 (7%)
Query: 7 SSSYLSRSGGGG---GGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYG--GGSSRVC 61
S + SGG G GGG SG S S R S S GG GGG S GYG GGS
Sbjct: 514 SKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRY 573
Query: 62 GRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGG 121
G GGG G GGG G G S GGG GGS +SGGGY S GG G SG
Sbjct: 574 GSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGS-----SSGGGYGSGGGGSSSVKGSSGE 628
Query: 122 GFGGGYGSGF 131
FG F
Sbjct: 629 AFGSSVTFSF 638
Score = 38.9 bits (89), Expect = 0.014
Identities = 22/46 (47%), Positives = 23/46 (50%), Gaps = 3/46 (6%)
Query: 578 SRGGSGGSHGGGSGFGG---ESGGSYGGGEEASGSGGGYGGGSGKS 620
S+ GGS G GS GG SYG G SGS GG GGG S
Sbjct: 514 SKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSIS 559
>gi|4504927 keratin 36 [Homo sapiens]
Length = 467
Score = 303 bits (775), Expect = 4e-82
Identities = 175/385 (45%), Positives = 240/385 (62%), Gaps = 5/385 (1%)
Query: 76 GSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFG 135
G+ GG S S G R A GY SS G G G G Y S
Sbjct: 20 GTAGGISRVSSIRSVGS-CRVPSLAGAAGYISSARSGLS---GLGSCLPGSYLSSECHTS 75
Query: 136 GFGGGAGGGDGGILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPA 195
GF G G G +EK TMQ LN RLA+YL+KV+ LE N +LE++IQ+WY+ + P
Sbjct: 76 GFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPY 135
Query: 196 AIQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDA 255
I +Y Y+ TI+D + +I+ N + +L IDN ++ DDFR K+E E +LRQ V+A
Sbjct: 136 -ICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEA 194
Query: 256 DINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAP 315
DINGLR++LD LT+ K+DLE Q E+L+EELM LKKNH+EE+S L Q +NVE++ AP
Sbjct: 195 DINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAP 254
Query: 316 GKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRH 375
DL K L DMR +YE L+ NR+D+E + TQ ++ +V SS +++Q E+ +LR
Sbjct: 255 PVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRR 314
Query: 376 GVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQ 435
V LEIELQ+Q S + +LE +L +T+ RY QL +Q ISN+EAQ++++R ++E QNQ
Sbjct: 315 TVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQ 374
Query: 436 EYSLLLSIKMRLEKEIETYHNLLEG 460
EY +LL +K RLE EI TY +LLEG
Sbjct: 375 EYQVLLDVKARLEGEIATYRHLLEG 399
>gi|94538345 keratin 35 [Homo sapiens]
Length = 455
Score = 300 bits (768), Expect = 3e-81
Identities = 173/411 (42%), Positives = 249/411 (60%), Gaps = 18/411 (4%)
Query: 51 SGYGGGSSRVCGRGGGGSFGYS--YGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSS 108
+G+ GS + G GGS S Y S S S + F S G G +S S
Sbjct: 8 AGFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSSYRATSCL 67
Query: 109 GGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRLASYL 168
GGF Y G G FG GILT NEK TMQ LN RLA YL
Sbjct: 68 PALCL-----PAGGFATSYSGGGGWFGE----------GILTGNEKETMQSLNDRLAGYL 112
Query: 169 DKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLD 228
+KV+ LE+ N LE++I++W +++ P +Y Y+ TI++L+ + + N + +++
Sbjct: 113 EKVRQLEQENASLESRIREWCEQQVPYMCP-DYQSYFRTIEELQKKTLCSKAENARLVVE 171
Query: 229 IDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMAL 288
IDN ++ DDFR K+E E +LRQ V++DINGLR++LD+LT+ KSDLE Q E+L+EEL+ L
Sbjct: 172 IDNAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCL 231
Query: 289 KKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQ 348
KKNH+EE++ L Q +NVE++ AP DL + L +MR +YE L+ NR+D E+ +TQ
Sbjct: 232 KKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQ 291
Query: 349 ITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQ 408
++ +V SS +++QS E+ +LR V LEIELQ+Q S + ALE +L +T+ RY Q
Sbjct: 292 SEELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQ 351
Query: 409 LQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLE 459
L +Q I+N+EAQ+ ++R ++E QNQEY +LL ++ RLE EI TY LLE
Sbjct: 352 LAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLE 402
>gi|27894337 keratin 20 [Homo sapiens]
Length = 424
Score = 287 bits (734), Expect = 2e-77
Identities = 151/344 (43%), Positives = 221/344 (64%), Gaps = 13/344 (3%)
Query: 129 SGFGGFGGFG------------GGAGGGDGGILTANEKSTMQELNSRLASYLDKVQALEE 176
S +GG GG G G G G + NEK MQ LN RLASYL+KV+ LE+
Sbjct: 34 SVYGGAGGRGIRISNSRHTVNYGSDLTGGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQ 93
Query: 177 ANNDLENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTL 236
+N+ LE +I+ WY+ P A ++YS YY I++L+ QI D + N + +L IDN ++
Sbjct: 94 SNSKLEVQIKQWYETNAPRA-GRDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAA 152
Query: 237 DDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEM 296
+DFR+K+E E+ +R V+AD+ GL +V D+LT+ K+DLE+Q E L ++L LKK H+EE+
Sbjct: 153 EDFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEV 212
Query: 297 SQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEV 356
L VNVE++ APG +L +N+MRQ+YE + KN ++ + Q+E Q ++ +V
Sbjct: 213 DGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQV 272
Query: 357 SSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQI 416
+ + +E++ + ++T+LR Q LEIELQS LS K +LE +LE+TK RY QL +Q +
Sbjct: 273 TVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLL 332
Query: 417 SNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEG 460
S+LEAQ+ +R +E QN EY +LL IK RLE+EI TY LLEG
Sbjct: 333 SSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEG 376
>gi|109148552 keratin 3 [Homo sapiens]
Length = 628
Score = 282 bits (721), Expect = 7e-76
Identities = 201/632 (31%), Positives = 315/632 (49%), Gaps = 77/632 (12%)
Query: 8 SSYLSRSGGGGGGGLGSGGSIRSSYSRFS--SSGGGGGGGRFSSSSGYGG-GSSRVCGRG 64
S S++ GGG G ++ S SR S + GG GGG + SG GG GS + G
Sbjct: 2 SRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLG 61
Query: 65 GGGSF------GYSYGGGSGGGFSASSLGGGFGGG-SRGFGGASGGGYSSSGGFGGGFGG 117
G S G S GG GGG S+ + GG+GGG G+GG GGG+ G GGGFGG
Sbjct: 62 GNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGG 121
Query: 118 GSG----GGFGG--GYGS--GFGGFGGFGG----------GAGGGDGGI----------- 148
G GGFGG G+G GFGG GGFGG G GG GGI
Sbjct: 122 AGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQ 181
Query: 149 ------------LTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAA 196
+ A E+ ++ LN++ AS++DKV+ LE+ N LE K + ++G ++
Sbjct: 182 PLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETK-WNLLQQQGTSS 240
Query: 197 IQ--KNYSPYY-NTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGV 253
I N P + N I+ L+ + ++ + ++ N ++DF+ K+E E N R
Sbjct: 241 ISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAA 300
Query: 254 DADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINV 313
+ + L++ +D+ M K +L+ + + L +E+ L+ + E+SQ+ S D +V +++
Sbjct: 301 ENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHIS-DTSVVLSM 359
Query: 314 APGK--DLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVT 371
+ DL + ++R +YE + +++ + E Y+T++ +++ G +++++ E+
Sbjct: 360 DNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEII 419
Query: 372 QLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIE 431
+L +Q L E++ + A L+ ++ + + L+ ++ L+A + + ++
Sbjct: 420 ELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLA 479
Query: 432 CQNQEYSLLLSIKMRLEKEIETYHNLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRG 491
++Y L+++K+ L+ EI TY LLEG + + + S S S G
Sbjct: 480 RLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTS---ASAG 536
Query: 492 GSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHS 551
G GG YGGG GGG GGG + GGSG SG G G GGG GGG GGG SG SGG
Sbjct: 537 GYGGGYGGG-MGGGLGGGFSAGGGSG------SGFGRGGGGGIGGGFGGGSSGFSGGSGF 589
Query: 552 GG-SGGNYGGGSGSGGGSGGGYGGGSGSRGGS 582
G SG Y G SGGG+ S +RGGS
Sbjct: 590 GSISGARY-------GVSGGGFSSAS-NRGGS 613
Score = 261 bits (667), Expect = 1e-69
Identities = 199/608 (32%), Positives = 304/608 (50%), Gaps = 62/608 (10%)
Query: 1 MSCRQFSS-----SYLSRSGGGGGGG-----LGSGGSIRSSYSRFSSSGGGGGGGRFSSS 50
MSC S +Y RSG GG G LG SI S + S GG GGGR S +
Sbjct: 29 MSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISVAAGGSRAGGFGGGRSSCA 88
Query: 51 --SGYGGGSSRVCGRGGGGSFG--YSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYS 106
GYGGG G G GG FG GGG GG GGFGG GFGGA GG+
Sbjct: 89 FAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGG-------AGGFGGAG-GFGGA--GGFG 138
Query: 107 SSGGFG--GGFGGGSGGGFGGGYGSGFGGFGGFGGGAG----------------GGDGGI 148
GGFG GGFGG G GG+G GGF GG G
Sbjct: 139 GPGGFGGSGGFGGPGSLGSPGGFGP-----GGFPGGIQEVTINQSLLQPLNVEIDPQIGQ 193
Query: 149 LTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQ--KNYSPYY- 205
+ A E+ ++ LN++ AS++DKV+ LE+ N LE K + ++G ++I N P +
Sbjct: 194 VKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETK-WNLLQQQGTSSISGTNNLEPLFE 252
Query: 206 NTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLD 265
N I+ L+ + ++ + ++ N ++DF+ K+E E N R + + L++ +D
Sbjct: 253 NHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDVD 312
Query: 266 NLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGK--DLTKTL 323
+ M K +L+ + + L +E+ L+ + E+SQ+ S D +V +++ + DL +
Sbjct: 313 SAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHIS-DTSVVLSMDNNRSLDLDSII 371
Query: 324 NDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIE 383
++R +YE + +++ + E Y+T++ +++ G +++++ E+ +L +Q L E
Sbjct: 372 AEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAE 431
Query: 384 LQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSI 443
++ + A L+ ++ + + L+ ++ L+A + + ++ ++Y L+++
Sbjct: 432 IEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNV 491
Query: 444 KMRLEKEIETYHNLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSG 503
K+ L+ EI TY LLEG E++ SG + S S S GG GG Y GGG G
Sbjct: 492 KLALDVEIATYRKLLEG--EEYRMSGECPSAVSISVVS-SSTTSASAGGYGGGY-GGGMG 547
Query: 504 GGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSG-GGHSGGSGGNYGGGS 562
GG GGG + GGSG G G G GGG GGG+GGGS G SGGSG G SG G GGG
Sbjct: 548 GGLGGGFSAGGGSGS--GFGRGGGGGIGGGFGGGS-SGFSGGSGFGSISGARYGVSGGGF 604
Query: 563 GSGGGSGG 570
S GG
Sbjct: 605 SSASNRGG 612
Score = 114 bits (284), Expect = 3e-25
Identities = 70/162 (43%), Positives = 83/162 (51%), Gaps = 15/162 (9%)
Query: 466 ESSGAGKIGLGGR-----GGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSY 520
++SG G G GR G S S S G GG+YG GG+G S G S
Sbjct: 7 KTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSI 66
Query: 521 GGGSGSGGGSGGGYGGGS-----GGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYG-G 574
+GG GG+GGG GG+ GG G G+ GG GG +GGG G GGG GG G G
Sbjct: 67 SISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFG 126
Query: 575 GSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGG 616
G+G GG+GG GG GFGG G GG + GS GG+G G
Sbjct: 127 GAGGFGGAGG-FGGPGGFGGSGG---FGGPGSLGSPGGFGPG 164
Score = 75.5 bits (184), Expect = 1e-13
Identities = 59/142 (41%), Positives = 68/142 (47%), Gaps = 19/142 (13%)
Query: 487 RGSRGGSGGSYGGGGSGGGYGGGSG------SRGGSGGSYGGGSGSGG-GSGGGY--GGG 537
+ S+ GGS G G G S S G GG+YG SG+GG GS Y GG
Sbjct: 4 QASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGN 63
Query: 538 SGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESG 597
S +GG +GG +GGG S +GG YGGG GS G GG GGG FGG G
Sbjct: 64 KSISISVAAGGSRAGG----FGGGRSSCAFAGG-YGGGFGS--GYGGGFGGG--FGGGRG 114
Query: 598 -GSYGGGEEASGSGGGYGGGSG 618
G GG G GG+GG G
Sbjct: 115 MGGGFGGAGGFGGAGGFGGAGG 136
Score = 72.8 bits (177), Expect = 9e-13
Identities = 42/82 (51%), Positives = 44/82 (53%), Gaps = 1/82 (1%)
Query: 543 SGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGG 602
S + +GG GG YGGG G G G G GGGSGS G GG G G GFGG S G GG
Sbjct: 527 SSSTTSASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGG 586
Query: 603 GEEASGSGGGYG-GGSGKSSHS 623
S SG YG G G SS S
Sbjct: 587 SGFGSISGARYGVSGGGFSSAS 608
Score = 71.2 bits (173), Expect = 3e-12
Identities = 49/115 (42%), Positives = 54/115 (46%), Gaps = 21/115 (18%)
Query: 57 SSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGG-SRGFGGASGGGYSSSGGFGGGF 115
SS GG YGGG GGG +GGG GGG S G G SG G GG GGGF
Sbjct: 527 SSSTTSASAGG-----YGGGYGGG-----MGGGLGGGFSAGGGSGSGFGRGGGGGIGGGF 576
Query: 116 GGGSGGGFGGGYGSGFGGFGGFGGGAGGGD-------GGILTANEKSTMQELNSR 163
GGGS G G GSGFG G G GG GG + ++ S + SR
Sbjct: 577 GGGSSGFSG---GSGFGSISGARYGVSGGGFSSASNRGGSIKFSQSSQSSQRYSR 628
Score = 33.5 bits (75), Expect = 0.60
Identities = 27/61 (44%), Positives = 28/61 (45%), Gaps = 16/61 (26%)
Query: 7 SSSYLSRSGGGG-GGGLGSGGSIRSSYSRFSS--------SGGG-------GGGGRFSSS 50
S S R GGGG GGG G G S S S F S SGGG GG +FS S
Sbjct: 560 SGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSISGARYGVSGGGFSSASNRGGSIKFSQS 619
Query: 51 S 51
S
Sbjct: 620 S 620
>gi|27894339 keratin 23 [Homo sapiens]
Length = 422
Score = 274 bits (701), Expect = 2e-73
Identities = 155/366 (42%), Positives = 228/366 (62%), Gaps = 26/366 (7%)
Query: 122 GFGGGYG---------SGFGGFGGF--------------GGGAGGGDGG-ILTANEKSTM 157
G GGG+G + GG GG GG G G +L N K+TM
Sbjct: 17 GAGGGWGRPRSFPRAPTVHGGAGGARISLSFTTRSCPPPGGSWGSGRSSPLLGGNGKATM 76
Query: 158 QELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVD 217
Q LN RLASYL+KV+ALEEAN LE++I W+ ++ P + +K+YS Y I L++QIVD
Sbjct: 77 QNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDPGS-KKDYSQYEENITHLQEQIVD 135
Query: 218 LTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQ 277
+ N + +L IDN RM +DDF +K+E E + ++ ++ ++ GLR+ LDNLT+ +DLE +
Sbjct: 136 GKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEIEVEGLRRTLDNLTIVTTDLEQE 195
Query: 278 YETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKN 337
E +++EL+ +KK+H++EM + + +VNV+++ P +DL K L DMRQEYE +I K
Sbjct: 196 VEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTGPREDLIKVLEDMRQEYELIIKKK 255
Query: 338 RKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKS 397
+D++ Y+ Q + E +S VQS ++ +L+ Q LEI+LQ+Q S K+ALE
Sbjct: 256 HRDLDTWYKEQSAAMSQEAASPA-TVQSRQGDIHELKRTFQALEIDLQTQYSTKSALENM 314
Query: 398 LEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNL 457
L +T++RY +LQ +QE IS+ E ++T +R E+E QN EY +LL IK LEKEI TY L
Sbjct: 315 LSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQVLLGIKTHLEKEITTYRRL 374
Query: 458 LEGGQE 463
LEG E
Sbjct: 375 LEGESE 380
>gi|116488398 keratin 32 [Homo sapiens]
Length = 448
Score = 272 bits (696), Expect = 6e-73
Identities = 140/327 (42%), Positives = 217/327 (66%), Gaps = 4/327 (1%)
Query: 136 GFGGGAGGGDG---GILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKK 192
G G G G G NEK TMQ LN RLASYL +V+ LE+ N +LE++IQ+
Sbjct: 76 GISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQE-ASHS 134
Query: 193 GPAAIQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQG 252
+ +Y ++ TI++L+ +I+ N + +++IDN ++ DDFR K+E E +RQ
Sbjct: 135 QVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQL 194
Query: 253 VDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEIN 312
V+ADINGLR++LD+LT+ K+DLE Q E+L+EELM LKKNH+EE+ L Q +N+E++
Sbjct: 195 VEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEVD 254
Query: 313 VAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQ 372
AP DLT+ L +MR +YE ++ NR+D+E + Q+ ++ +V++S +++Q+ ++
Sbjct: 255 AAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDIID 314
Query: 373 LRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIEC 432
LR V LEIELQ+Q S + +LE +L +++ RY QL +Q I+N+EAQ+ ++R ++E
Sbjct: 315 LRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLER 374
Query: 433 QNQEYSLLLSIKMRLEKEIETYHNLLE 459
QNQEY +LL ++ RLE EI TY +LLE
Sbjct: 375 QNQEYQVLLDVRARLEGEINTYRSLLE 401
>gi|148277620 type I hair keratin KA35 [Homo sapiens]
Length = 491
Score = 270 bits (691), Expect = 2e-72
Identities = 143/316 (45%), Positives = 211/316 (66%), Gaps = 3/316 (0%)
Query: 144 GDGGILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSP 203
G+G + +NEK TMQ LN RLA+YL KV+ LE N +LE+KIQ+ +K+ P + +Y
Sbjct: 89 GEG--INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPV-LCPDYLS 145
Query: 204 YYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQV 263
YY TI++L+ +I+ N++ + IDNT++T DD R K+E E +LRQ V++D NGL+Q+
Sbjct: 146 YYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQI 205
Query: 264 LDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTL 323
L+ LT+ K+DLE Q ++L+EEL+ LK NHKEE++ L Q +++E+ AP DL + L
Sbjct: 206 LNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVL 265
Query: 324 NDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIE 383
+MR +YE ++ NRKD+E + TQI ++ +V +S Q+ Q KE+ +LR V LE+E
Sbjct: 266 QEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVE 325
Query: 384 LQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSI 443
LQ+Q + + E L +T+ RY L IQ I NLEAQ+ ++R +E QNQEY +LL +
Sbjct: 326 LQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDV 385
Query: 444 KMRLEKEIETYHNLLE 459
K RLE EI TY +LLE
Sbjct: 386 KSRLECEITTYRSLLE 401
>gi|153791670 keratin 76 [Homo sapiens]
Length = 638
Score = 270 bits (690), Expect = 3e-72
Identities = 197/634 (31%), Positives = 316/634 (49%), Gaps = 67/634 (10%)
Query: 9 SYLSRSGG-GGGGGLGSGGSIRSSYSRFSSSGGGG-----GGGRFSSSSGYGGGSSRVCG 62
S+ RS G G + SG S S +R +GGG G G F S S Y GS++
Sbjct: 9 SFSGRSQGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRSGAGSFGSRSLYNLGSNKSIS 68
Query: 63 RGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGG 122
G S GG GGG S+ GG+GGG FGG+ GGG+ G G GFGG G G
Sbjct: 69 ISVAA--GSSRAGGFGGGRSSCGFAGGYGGG---FGGSYGGGFGGGRGVGSGFGGAGGFG 123
Query: 123 FGGGYGSG--FGGFGGFGGGAGGGDGGI---------------------------LTANE 153
GG+G FGG G FGG G G GG + A E
Sbjct: 124 GAGGFGGPGVFGGPGSFGGPGGFGPGGFPGGIQEVIVNQSLLQPLNVEIDPQIGQVKAQE 183
Query: 154 KSTMQELNSRLASYLDKVQALEEANNDLENK---IQDWYDKKGPAAIQKNYSPYYN---- 206
+ ++ LN++ AS++DKV+ LE+ N LE K +Q GP++++ + Y +
Sbjct: 184 REQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFESYISFLCK 243
Query: 207 TIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDN 266
+D L + +L G K++ D+ ++DF+ K+E E N R + + GL++ +D
Sbjct: 244 QLDSLLGERGNLE-GELKSMQDL------VEDFKKKYEDEINKRTAAENEFVGLKKDVDA 296
Query: 267 LTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGK--DLTKTLN 324
M K +L+ + ++L +E+ L+ ++ E+SQ+ S D +V +++ + DL +
Sbjct: 297 AFMNKVELQAKVDSLTDEVSFLRTLYEMELSQMQSHAS-DTSVVLSMDNNRCLDLGSIIA 355
Query: 325 DMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIEL 384
++R +YE++ +++ + E Y+T++ +++ G +++++ E+ +L +Q L E+
Sbjct: 356 EVRAQYEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEI 415
Query: 385 QSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIK 444
++ + A L+ ++ + + R L+ ++ +L+ + + ++ ++Y L+++K
Sbjct: 416 ENVKKQNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVK 475
Query: 445 MRLEKEIETYHNLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGG-GGSG 503
+ L+ EI TY LLEG E+ SG + + S + GS G S G +GG GSG
Sbjct: 476 LALDVEIATYRKLLEG--EECRMSGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSG 533
Query: 504 GGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSG-GSGGGHSGGSGGNYGGGS 562
G G +GGS S G G GGSG GYGG S G G GS G + S G+ GG+
Sbjct: 534 SG-----GYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGRGSSGSYQSSSSGSRLGGA 588
Query: 563 GSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGES 596
GS S G G SGS SGGS G SG GG +
Sbjct: 589 GSISVSHSGMGSSSGSIQTSGGS-GYKSGGGGST 621
Score = 87.8 bits (216), Expect = 3e-17
Identities = 64/149 (42%), Positives = 72/149 (48%), Gaps = 16/149 (10%)
Query: 474 GLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGS-GSRG----GSGGSYGGGSGSGG 528
G GR R S G GGG G G GS GSR GS S +G
Sbjct: 16 GFSGRSAVVSGSSRMSCVARSGGAGGGACGFRSGAGSFGSRSLYNLGSNKSISISVAAGS 75
Query: 529 GSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGG 588
GG+GGG S G GG+ GG GG+YGGG G G G G G+GG G GG+GG GG
Sbjct: 76 SRAGGFGGGRS---SCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAGGF-GGAGG-FGG 130
Query: 589 GSGFGGESGGSYGGGEEASGSG-GGYGGG 616
FGG GS+GG G G GG+ GG
Sbjct: 131 PGVFGGP--GSFGG---PGGFGPGGFPGG 154
Score = 80.1 bits (196), Expect = 6e-15
Identities = 58/142 (40%), Positives = 67/142 (47%), Gaps = 8/142 (5%)
Query: 479 GGSGGSYGRGSR-GGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGS--GSGGGSGGGYG 535
G S G GR + GS SGG GG G R G+G S+G S G
Sbjct: 12 GRSQGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRSGAG-SFGSRSLYNLGSNKSISIS 70
Query: 536 GGSGGGHSGGSGGGHSG-GSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGG 594
+G +GG GGG S G G YGGG G G GGG+GGG G G GG+ GG G GG
Sbjct: 71 VAAGSSRAGGFGGGRSSCGFAGGYGGGFG--GSYGGGFGGGRGVGSGFGGA-GGFGGAGG 127
Query: 595 ESGGSYGGGEEASGSGGGYGGG 616
G GG + G GG+G G
Sbjct: 128 FGGPGVFGGPGSFGGPGGFGPG 149
Score = 69.7 bits (169), Expect = 8e-12
Identities = 47/117 (40%), Positives = 53/117 (45%), Gaps = 14/117 (11%)
Query: 510 SGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSG------ 563
SG G G SGS S GG+GGG G G S GS Y GS
Sbjct: 11 SGRSQGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRSGAGSFGSRSLYNLGSNKSISIS 70
Query: 564 --SGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSG 618
+G GG+GGG S G +GG G GFGG GG +GGG G G G+GG G
Sbjct: 71 VAAGSSRAGGFGGGRSSCGFAGGY---GGGFGGSYGGGFGGGR---GVGSGFGGAGG 121
Score = 64.7 bits (156), Expect = 2e-10
Identities = 50/124 (40%), Positives = 57/124 (45%), Gaps = 14/124 (11%)
Query: 502 SGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGS------- 554
SG G S SG S GG+GGG G G S GS ++ GS
Sbjct: 11 SGRSQGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRSGAGSFGSRSLYNLGSNKSISIS 70
Query: 555 ---GGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGG 611
G + GG G GG S G+ GG G GG GGS+GGG G GG GS GG G G
Sbjct: 71 VAAGSSRAGGFG-GGRSSCGFAGGYG--GGFGGSYGGGFG-GGRGVGSGFGGAGGFGGAG 126
Query: 612 GYGG 615
G+GG
Sbjct: 127 GFGG 130
Score = 62.0 bits (149), Expect = 2e-09
Identities = 42/84 (50%), Positives = 45/84 (53%), Gaps = 9/84 (10%)
Query: 546 SGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGG--SHGGGSGFGGESGGSYGG- 602
S G SG S G +GG SGSG G GY GGS S SG S G GSG+GG S GS GG
Sbjct: 514 STSGSSGSSRGVFGGVSGSGSG---GYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGR 570
Query: 603 ---GEEASGSGGGYGGGSGKSSHS 623
G S S G GG+G S S
Sbjct: 571 GSSGSYQSSSSGSRLGGAGSISVS 594
Score = 61.6 bits (148), Expect = 2e-09
Identities = 52/126 (41%), Positives = 59/126 (46%), Gaps = 22/126 (17%)
Query: 3 CRQFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGG--GGGRFSSSSGYG--GGSS 58
C S+ S S GS GS R + S SG GG GG SSSSGYG GGS
Sbjct: 505 CISVVSNVTSTS--------GSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGS- 555
Query: 59 RVCGRG-GGGSFGYSYGGGSGGGFSASSLGGGFGGG-----SRGFGGASGGGYSSSGGFG 112
G G GG S G + G GS G + +SS G GG S G+S G +SGG G
Sbjct: 556 ---GSGYGGVSSGSTGGRGSSGSYQSSSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSG 612
Query: 113 GGFGGG 118
GGG
Sbjct: 613 YKSGGG 618
Score = 57.8 bits (138), Expect = 3e-08
Identities = 51/141 (36%), Positives = 62/141 (43%), Gaps = 17/141 (12%)
Query: 27 SIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSL 86
++ S+ SS G GG S S GY GGSS S GY GGSG G+
Sbjct: 511 NVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSS------SSSSSGYGVSGGSGSGY----- 559
Query: 87 GGGFGGGSRGFGGASGGGYSSSGGF-GGGFGGGSGGGFGGGYGSG---FGGFGGFGGGAG 142
GG GS G G+SG SSS G GG G S G G SG G G+ G G
Sbjct: 560 -GGVSSGSTGGRGSSGSYQSSSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSGYKSG-G 617
Query: 143 GGDGGILTANEKSTMQELNSR 163
GG I + S+ Q +++
Sbjct: 618 GGSTSIRFSQTTSSSQHSSTK 638
Score = 48.5 bits (114), Expect = 2e-05
Identities = 36/97 (37%), Positives = 42/97 (43%), Gaps = 6/97 (6%)
Query: 526 SGGGSGGGYGGGSG--GGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSG 583
S G G+ G S G S S SGG+GG G G G+G +G S GS
Sbjct: 9 SFSGRSQGFSGRSAVVSGSSRMSCVARSGGAGG---GACGFRSGAGS-FGSRSLYNLGSN 64
Query: 584 GSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKS 620
S G G +GGG + G GGYGGG G S
Sbjct: 65 KSISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGS 101
Score = 45.1 bits (105), Expect = 2e-04
Identities = 35/74 (47%), Positives = 40/74 (54%), Gaps = 10/74 (13%)
Query: 557 NYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGG------SGFGGESGGSYGGGEEASGSG 610
N SGS G S G +GG SGS GSGG + GG SG+G G G G +SGS
Sbjct: 511 NVTSTSGSSGSSRGVFGGVSGS--GSGG-YKGGSSSSSSSGYGVSGGSGSGYGGVSSGST 567
Query: 611 GGYG-GGSGKSSHS 623
GG G GS +SS S
Sbjct: 568 GGRGSSGSYQSSSS 581
Score = 43.1 bits (100), Expect = 8e-04
Identities = 39/92 (42%), Positives = 44/92 (47%), Gaps = 17/92 (18%)
Query: 7 SSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGG 66
SSS S G GG G G GG S S+ G G G SSSSG SR+ GG
Sbjct: 542 SSSSSSGYGVSGGSGSGYGG-----VSSGSTGGRGSSGSYQSSSSG-----SRL---GGA 588
Query: 67 GSFGYSYGG-GSGGGFSASSLGGGF---GGGS 94
GS S+ G GS G +S G G+ GGGS
Sbjct: 589 GSISVSHSGMGSSSGSIQTSGGSGYKSGGGGS 620
Score = 30.8 bits (68), Expect = 3.9
Identities = 24/60 (40%), Positives = 28/60 (46%), Gaps = 9/60 (15%)
Query: 4 RQFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGG---GGGGRFSSSSGYGGGSSRV 60
R S SY S S G LG GSI S+S SS G GG + S GGGS+ +
Sbjct: 570 RGSSGSYQSSSSGSR---LGGAGSISVSHSGMGSSSGSIQTSGGSGYKSG---GGGSTSI 623
Score = 30.0 bits (66), Expect = 6.6
Identities = 25/59 (42%), Positives = 31/59 (52%), Gaps = 7/59 (11%)
Query: 7 SSSYLSRSGGGGG-----GGLGSG-GSIRSSY-SRFSSSGGGGGGGRFSSSSGYGGGSS 58
SSS SR GG G G+GS GSI++S S + S GGG RFS ++ SS
Sbjct: 578 SSSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSGYKSGGGGSTSIRFSQTTSSSQHSS 636
>gi|40354195 keratin 18 [Homo sapiens]
Length = 430
Score = 270 bits (690), Expect = 3e-72
Identities = 155/367 (42%), Positives = 227/367 (61%), Gaps = 8/367 (2%)
Query: 105 YSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRL 164
Y+ +GG G F GG GSG G G GG G GGI NEK TMQ LN RL
Sbjct: 36 YAGAGGSGSRISVSRSTSFRGGMGSG-GLATGIAGGLAGM-GGI--QNEKETMQSLNDRL 91
Query: 165 ASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVDLTVGNNK 224
ASYLD+V++LE N LE+KI++ +KKGP +++S Y+ I+DL+ QI TV N +
Sbjct: 92 ASYLDRVRSLETENRRLESKIREHLEKKGPQV--RDWSHYFKIIEDLRAQIFANTVDNAR 149
Query: 225 TLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEE 284
+L IDN R+ DDFR+K+E E +RQ V+ DI+GLR+V+D+ + + LE + E L+EE
Sbjct: 150 IVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEE 209
Query: 285 LMALKKNHKEEMSQLTGQ-NSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIEN 343
L+ +KKNH+EE+ L Q S + VE++ +DL K + D+R +Y++L KNR++++
Sbjct: 210 LLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNREELDK 269
Query: 344 QYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKN 403
+ QI + V++ EV ++ +T+LR VQ LEI+L S + KA+LE SL + +
Sbjct: 270 YWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEA 329
Query: 404 RYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEGGQE 463
RY Q++ + + +LE+++ R E + Q QEY LL+IK++LE EI TY LLE G E
Sbjct: 330 RYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDG-E 388
Query: 464 DFESSGA 470
DF A
Sbjct: 389 DFNLGDA 395
Score = 30.8 bits (68), Expect = 3.9
Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 5/58 (8%)
Query: 484 SYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGG 541
SYG + Y G G G GS S+ GG GSGG + G GG +G G
Sbjct: 23 SYGARPVSSAASVYAGAG-----GSGSRISVSRSTSFRGGMGSGGLATGIAGGLAGMG 75
Score = 29.6 bits (65), Expect = 8.7
Identities = 18/39 (46%), Positives = 20/39 (51%)
Query: 480 GSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGG 518
G+GGS R S S GG GSGG G +G G GG
Sbjct: 38 GAGGSGSRISVSRSTSFRGGMGSGGLATGIAGGLAGMGG 76
>gi|4557888 keratin 18 [Homo sapiens]
Length = 430
Score = 270 bits (690), Expect = 3e-72
Identities = 155/367 (42%), Positives = 227/367 (61%), Gaps = 8/367 (2%)
Query: 105 YSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRL 164
Y+ +GG G F GG GSG G G GG G GGI NEK TMQ LN RL
Sbjct: 36 YAGAGGSGSRISVSRSTSFRGGMGSG-GLATGIAGGLAGM-GGI--QNEKETMQSLNDRL 91
Query: 165 ASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVDLTVGNNK 224
ASYLD+V++LE N LE+KI++ +KKGP +++S Y+ I+DL+ QI TV N +
Sbjct: 92 ASYLDRVRSLETENRRLESKIREHLEKKGPQV--RDWSHYFKIIEDLRAQIFANTVDNAR 149
Query: 225 TLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEE 284
+L IDN R+ DDFR+K+E E +RQ V+ DI+GLR+V+D+ + + LE + E L+EE
Sbjct: 150 IVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEE 209
Query: 285 LMALKKNHKEEMSQLTGQ-NSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIEN 343
L+ +KKNH+EE+ L Q S + VE++ +DL K + D+R +Y++L KNR++++
Sbjct: 210 LLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNREELDK 269
Query: 344 QYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKN 403
+ QI + V++ EV ++ +T+LR VQ LEI+L S + KA+LE SL + +
Sbjct: 270 YWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEA 329
Query: 404 RYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEGGQE 463
RY Q++ + + +LE+++ R E + Q QEY LL+IK++LE EI TY LLE G E
Sbjct: 330 RYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDG-E 388
Query: 464 DFESSGA 470
DF A
Sbjct: 389 DFNLGDA 395
Score = 30.8 bits (68), Expect = 3.9
Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 5/58 (8%)
Query: 484 SYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGG 541
SYG + Y G G G GS S+ GG GSGG + G GG +G G
Sbjct: 23 SYGARPVSSAASVYAGAG-----GSGSRISVSRSTSFRGGMGSGGLATGIAGGLAGMG 75
Score = 29.6 bits (65), Expect = 8.7
Identities = 18/39 (46%), Positives = 20/39 (51%)
Query: 480 GSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGG 518
G+GGS R S S GG GSGG G +G G GG
Sbjct: 38 GAGGSGSRISVSRSTSFRGGMGSGGLATGIAGGLAGMGG 76
>gi|10337581 type I hair keratin 3B [Homo sapiens]
Length = 404
Score = 270 bits (690), Expect = 3e-72
Identities = 136/313 (43%), Positives = 215/313 (68%), Gaps = 1/313 (0%)
Query: 147 GILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYN 206
G +EK TMQ LN RLASYL+KV+ LE N +LEN I++ ++ P + +Y Y+
Sbjct: 50 GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPL-LCPSYQSYFK 108
Query: 207 TIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDN 266
TI++L+ +I+ N + ++ IDN ++ DDFR K++ EQ+LRQ V++DIN LR++LD
Sbjct: 109 TIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDE 168
Query: 267 LTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDM 326
LT+ +SDLE Q E+L+EEL++LK+NH++E++ L Q +NVE++ AP DL + LN+
Sbjct: 169 LTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNET 228
Query: 327 RQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQS 386
R +YE L+ NR+++E + TQ ++ +V SS +++QS E+ +LR V LEIELQ+
Sbjct: 229 RNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288
Query: 387 QLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMR 446
Q + + +LE +L +++ RY QL +Q I+N+E+Q+ ++R ++E QNQEY +LL ++ R
Sbjct: 289 QHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348
Query: 447 LEKEIETYHNLLE 459
LE EI TY +LLE
Sbjct: 349 LECEINTYRSLLE 361
>gi|14917115 keratin 31 [Homo sapiens]
Length = 416
Score = 270 bits (690), Expect = 3e-72
Identities = 137/313 (43%), Positives = 213/313 (68%), Gaps = 1/313 (0%)
Query: 147 GILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYN 206
G +EK TMQ LN RLASYL+KV+ LE N +LEN I++ ++ P + +Y Y+
Sbjct: 50 GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPL-LCPSYQSYFK 108
Query: 207 TIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDN 266
TI++L+ +I+ N + ++ IDN ++ DDFR K++ E +LRQ V++DINGLR++LD
Sbjct: 109 TIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDE 168
Query: 267 LTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDM 326
LT+ KSDLE Q E+L+EEL+ LK NH++E++ L Q +NVE++ AP DL + LN+
Sbjct: 169 LTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNET 228
Query: 327 RQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQS 386
R +YE L+ NR+++E + TQ ++ +V SS +++QS E+ +LR V LEIELQ+
Sbjct: 229 RSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288
Query: 387 QLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMR 446
Q + + +LE +L +++ RY QL +Q I+N+E+Q+ ++R ++E QNQEY +LL ++ R
Sbjct: 289 QHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348
Query: 447 LEKEIETYHNLLE 459
LE EI TY +LLE
Sbjct: 349 LECEINTYRSLLE 361
>gi|14917117 keratin 33A [Homo sapiens]
Length = 404
Score = 270 bits (689), Expect = 4e-72
Identities = 137/313 (43%), Positives = 214/313 (68%), Gaps = 1/313 (0%)
Query: 147 GILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYN 206
G +EK TMQ LN RLASYL+KV+ LE N +LEN I++ ++ P + +Y Y+
Sbjct: 50 GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPL-VCASYQSYFK 108
Query: 207 TIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDN 266
TI++L+ +I+ N + ++ IDN ++ DDFR K+E E +LRQ V++DINGLR++LD
Sbjct: 109 TIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDE 168
Query: 267 LTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDM 326
LT+ +SDLE Q E+L+EEL+ LK+NH++E++ L Q +NVE++ AP DL + LN+
Sbjct: 169 LTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNET 228
Query: 327 RQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQS 386
R +YE L+ NR+++E + TQ ++ +V SS +++QS E+ +LR V LEIELQ+
Sbjct: 229 RSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288
Query: 387 QLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMR 446
Q + + +LE +L +++ RY QL +Q I+N+E+Q+ ++R ++E QNQEY +LL ++ R
Sbjct: 289 QHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348
Query: 447 LEKEIETYHNLLE 459
LE EI TY +LLE
Sbjct: 349 LECEINTYRSLLE 361
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.135 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,002,100
Number of Sequences: 37866
Number of extensions: 2150657
Number of successful extensions: 138647
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1128
Number of HSP's successfully gapped in prelim test: 807
Number of HSP's that attempted gapping in prelim test: 20596
Number of HSP's gapped (non-prelim): 43650
length of query: 623
length of database: 18,247,518
effective HSP length: 108
effective length of query: 515
effective length of database: 14,157,990
effective search space: 7291364850
effective search space used: 7291364850
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.