Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 54873602

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|54873602 hypothetical protein LOC220382 [Homo sapiens]
         (426 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|54873602 hypothetical protein LOC220382 [Homo sapiens]             873   0.0  
gi|31543095 hypothetical protein LOC90050 [Homo sapiens]               57   4e-08
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    55   1e-07
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    55   1e-07
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    55   1e-07
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      52   8e-07
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    52   1e-06
gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens]        52   1e-06
gi|239752280 PREDICTED: similar to family with sequence similari...    51   2e-06
gi|210032463 family with sequence similarity 48, member B2 [Homo...    51   2e-06
gi|239757043 PREDICTED: functional smad suppressing element 18 [...    51   2e-06
gi|239751555 PREDICTED: functional smad suppressing element 18 [...    51   2e-06
gi|239746067 PREDICTED: functional smad suppressing element 18 [...    51   2e-06
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]          51   2e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni...    51   2e-06
gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]           50   4e-06
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       49   7e-06
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      49   1e-05
gi|84570137 homeobox B3 [Homo sapiens]                                 48   2e-05
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         48   2e-05
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          47   3e-05
gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]          47   3e-05
gi|157426823 NK2 homeobox 4 [Homo sapiens]                             47   3e-05
gi|5453936 POU class 3 homeobox 3 [Homo sapiens]                       47   3e-05
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 47   4e-05
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 47   4e-05
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     47   4e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    46   6e-05
gi|22027603 alpha 1 type XIII collagen isoform 16 [Homo sapiens]       46   6e-05
gi|22027593 alpha 1 type XIII collagen isoform 11 [Homo sapiens]       46   6e-05

>gi|54873602 hypothetical protein LOC220382 [Homo sapiens]
          Length = 426

 Score =  873 bits (2255), Expect = 0.0
 Identities = 426/426 (100%), Positives = 426/426 (100%)

Query: 1   MAVQAALLSTHPFVPFGFGGSPDGLGGAFGALDKGCCFEDDETGAPAGALLSGAEGGDVR 60
           MAVQAALLSTHPFVPFGFGGSPDGLGGAFGALDKGCCFEDDETGAPAGALLSGAEGGDVR
Sbjct: 1   MAVQAALLSTHPFVPFGFGGSPDGLGGAFGALDKGCCFEDDETGAPAGALLSGAEGGDVR 60

Query: 61  EATRDLLSFIDSASSNIKLALDKPGKSKRKVNHRKYLQKQIKRCSGLMGAAPPGPPSPSA 120
           EATRDLLSFIDSASSNIKLALDKPGKSKRKVNHRKYLQKQIKRCSGLMGAAPPGPPSPSA
Sbjct: 61  EATRDLLSFIDSASSNIKLALDKPGKSKRKVNHRKYLQKQIKRCSGLMGAAPPGPPSPSA 120

Query: 121 ADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALFDSLRHVPGGAE 180
           ADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALFDSLRHVPGGAE
Sbjct: 121 ADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALFDSLRHVPGGAE 180

Query: 181 PAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRARNLPPSFFTEPSRAGG 240
           PAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRARNLPPSFFTEPSRAGG
Sbjct: 181 PAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRARNLPPSFFTEPSRAGG 240

Query: 241 GGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGP 300
           GGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGP
Sbjct: 241 GGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGP 300

Query: 301 PELEPGLFEPPPAVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADS 360
           PELEPGLFEPPPAVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADS
Sbjct: 301 PELEPGLFEPPPAVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADS 360

Query: 361 PGGEDGRGHLASFAPFFPDCALPPPPPPHQVSYDYSAGYSRTAYSSLWRSDGVWEGAPGE 420
           PGGEDGRGHLASFAPFFPDCALPPPPPPHQVSYDYSAGYSRTAYSSLWRSDGVWEGAPGE
Sbjct: 361 PGGEDGRGHLASFAPFFPDCALPPPPPPHQVSYDYSAGYSRTAYSSLWRSDGVWEGAPGE 420

Query: 421 EGAHRD 426
           EGAHRD
Sbjct: 421 EGAHRD 426


>gi|31543095 hypothetical protein LOC90050 [Homo sapiens]
          Length = 354

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 63/221 (28%), Positives = 82/221 (37%), Gaps = 65/221 (29%)

Query: 66  LLSFIDSASSNIKLALDKPGKSKRKVNHRKYLQKQIKRCSGLMGAAPPGPPSPSAA---- 121
           LL+F++ ASS+IK ALDK    +R V+HRKYLQKQ+KR S      P G P  +A     
Sbjct: 72  LLNFVNLASSDIKAALDKSAPCRRSVDHRKYLQKQLKRFSQKYSRLPRGLPGRAAEPYLK 131

Query: 122 ----DTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALFDSLRHVPG 177
               D P  R L     P  ++P  G     +          L    L       R  P 
Sbjct: 132 RGSEDRP--RRLLLDLGPD-SSPGGGGGCKEKVLRSPYREECLAKEQLPQ-----RQHPE 183

Query: 178 GAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRARNLPPSFFTEPSR 237
            A+P                                     +VP+R R LP SF+ EP  
Sbjct: 184 AAQPG------------------------------------QVPMRKRQLPASFWEEPRP 207

Query: 238 AGG------GGCGP-SGPDVSLGDLEKGAEAVEFFELLGPD 271
                    GG GP  GP        +G +  +  E LGP+
Sbjct: 208 THSYHVGLEGGLGPREGPPY------EGKKNCKGLEPLGPE 242


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
           sapiens]
          Length = 1818

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 94/347 (27%), Positives = 119/347 (34%), Gaps = 52/347 (14%)

Query: 106 GLMG-AAPPGPPS----PSAADTPAKRPLAAPSAPTVAAP----AHGKAAPRREASQAAA 156
           GL G   PPG P     P     P    L  P    +  P      G   P   A +A A
Sbjct: 469 GLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQA 528

Query: 157 AASLQSRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGD--------VAGP 208
            A LQ   +A     LR  PG     G     P  G G +G  G  GD        V GP
Sbjct: 529 QAILQQARIA-----LRGPPGPMGLTGRP--GPVGGPGSSGAKGESGDPGPQGPRGVQGP 581

Query: 209 AGATAIPGARKVPLR--ARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFE 266
            G T  PG R  P     R +P     +  R   G  G  G     G  E+G +      
Sbjct: 582 PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRG--ERGPQGPP--G 637

Query: 267 LLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGPPEL--EPGL--FEPPPAVVGNLLYPE 322
             G D   G +  +     P +  P G    RG P    +PG+   + PP   GN+    
Sbjct: 638 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM---G 694

Query: 323 PWSVPGCSPTKKSP----LTAPRGGLTLNEPLSPL-YPAAADSPGGEDGRGHLASFAPFF 377
           P   PG    + +P    L  P+G +       P   P  A  PG +   GH        
Sbjct: 695 PQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSG 754

Query: 378 PDCALPPPPPPHQVSYDYSAGYSRTAYSSLWRSDGV--WEGAPGEEG 422
              AL PP P   + Y    G           +DGV   +G+ GE+G
Sbjct: 755 EKGALGPPGPQGPIGYPGPRGVK--------GADGVRGLKGSKGEKG 793



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 92/364 (25%), Positives = 105/364 (28%), Gaps = 87/364 (23%)

Query: 112  PPGPPSPSAADT----PAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAA 167
            P GPP P   D     P +R        T      G   P+    +              
Sbjct: 944  PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE-------- 995

Query: 168  LFDSLRHVPGGAEPAGGEVAAPAAGLGGA----GTGGAGGDVAGPAGATAIPGARKVP-- 221
                 R  PG   P G +    AAG  GA    G  G  G   GPAG    PG R +P  
Sbjct: 996  -----RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK-DGPAGLRGFPGERGLPGA 1049

Query: 222  LRARNL--------PPSFFTEPSRAGGGGC----------GPSGPDVSLGDLEKGAEAVE 263
              A  L        PP     P   G  G           GP GP    G  EKGA   +
Sbjct: 1050 QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG--EKGAPGEK 1107

Query: 264  FFELLGPDYGAGTEAAVLLAAEPLDVFPAGA---------------------SVLRGPPE 302
                 GP   AG +        P    PAG+                         GPP 
Sbjct: 1108 -----GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG 1162

Query: 303  LEPGLFEP--PPAVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADS 360
              PGL  P   P + G    P P    G    K        G      P  P+       
Sbjct: 1163 -PPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK-----GDEGARGFPGPPGPIGLQGLPG 1216

Query: 361  PGGEDG-RGHLASFAPFFPDCALPPPPPPHQVSYDYSAGYSRTAYSSLWRSDGVWE-GAP 418
            P GE G  G +    P       P PP P        A   +    S+    GV E G P
Sbjct: 1217 PPGEKGENGDVGPMGP-------PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEP 1269

Query: 419  GEEG 422
            GE G
Sbjct: 1270 GEAG 1273



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 101/389 (25%), Positives = 125/389 (32%), Gaps = 103/389 (26%)

Query: 20   GSPDGLGGAFGALDKGCCFEDDETGAPAGALLSGAEG--GDVREATRDLLSFIDSASSNI 77
            G P  +G   G  +KG   E    G P  A + G +G  G+  EA           ++  
Sbjct: 1252 GPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG-------PPGAAGP 1304

Query: 78   KLALDKPGKSKRKVNHRKYLQKQIKRCSGLMG-AAPPGPPSPSAADTPA--KRPLAAPSA 134
              A   PG    K N             G  G   PPG P P+  D     K     P  
Sbjct: 1305 PGAKGPPGDDGPKGNPGPV---------GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1355

Query: 135  PTVAAPAHGKAAP-----RREASQAAAAASLQSRSLAALFDSLRHVPGGAEPAGGEVAAP 189
            P    P+ G+A P     +R    AA A   Q               G    AG E   P
Sbjct: 1356 PGPPGPS-GEAGPPGPPGKRGPPGAAGAEGRQGEK------------GAKGEAGAE--GP 1400

Query: 190  AAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRARNLPPSFFTEPSRAGGGGCGPSGPD 249
                G  G  G  G   GP G   IPG    P+  + LP            G  GP GP 
Sbjct: 1401 PGKTGPVGPQGPAGK-PGPEGLRGIPG----PVGEQGLP---------GAAGQDGPPGP- 1445

Query: 250  VSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGPPELEPGLFE 309
                              +GP    G      L  +P      G+   +G P L  GL  
Sbjct: 1446 ------------------MGPPGLPG------LKGDP------GSKGEKGHPGL-IGLIG 1474

Query: 310  PPPAVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADS-PGGEDGRG 368
            PP    G         +PG   T+ SP     GG+    P  PL P      PG +  +G
Sbjct: 1475 PP----GEQGEKGDRGLPG---TQGSPGAKGDGGIP--GPAGPLGPPGPPGLPGPQGPKG 1525

Query: 369  HLASFAPFFP--DCALPPPP----PPHQV 391
            +  S  P     D  LP PP    PP +V
Sbjct: 1526 NKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1554



 Score = 33.9 bits (76), Expect = 0.29
 Identities = 72/290 (24%), Positives = 94/290 (32%), Gaps = 77/290 (26%)

Query: 106  GLMGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSL 165
            G MG  PPGPP P     P       P  P  +  + G    + E  +A           
Sbjct: 1228 GPMG--PPGPPGPRGPQGP--NGADGPQGPPGSVGSVGGVGEKGEPGEA----------- 1272

Query: 166  AALFDSLRHVPGGAEPAGGEVAAPAAGLGGA-GTGGAGGDVAGPAGATAIPGARKVP--- 221
                       G   P G       AG+GG  G  G  G+ AGP GA   PGA+  P   
Sbjct: 1273 -----------GNPGPPG------EAGVGGPKGERGEKGE-AGPPGAAGPPGAKGPPGDD 1314

Query: 222  -LRARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAV 280
              +    P  F  +P   G    GP+G D   GD  +  +  +     GP   +G     
Sbjct: 1315 GPKGNPGPVGFPGDPGPPGEP--GPAGQDGVGGDKGEDGDPGQ----PGPPGPSG----- 1363

Query: 281  LLAAEPLDVFPAGASVLRGPP--------ELEPGL-----FEPPPAVVGNLLYPEPWSVP 327
                   +  P G    RGPP        + E G       E PP   G +    P   P
Sbjct: 1364 -------EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1416

Query: 328  GCSPTKKSPLTAPRGGLT----LNEPLSPL----YPAAADSPGGEDGRGH 369
            G    +  P      GL      + P  P+     P     PG +  +GH
Sbjct: 1417 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGH 1466


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
           sapiens]
          Length = 1767

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 94/347 (27%), Positives = 119/347 (34%), Gaps = 52/347 (14%)

Query: 106 GLMG-AAPPGPPS----PSAADTPAKRPLAAPSAPTVAAP----AHGKAAPRREASQAAA 156
           GL G   PPG P     P     P    L  P    +  P      G   P   A +A A
Sbjct: 418 GLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQA 477

Query: 157 AASLQSRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGD--------VAGP 208
            A LQ   +A     LR  PG     G     P  G G +G  G  GD        V GP
Sbjct: 478 QAILQQARIA-----LRGPPGPMGLTGRP--GPVGGPGSSGAKGESGDPGPQGPRGVQGP 530

Query: 209 AGATAIPGARKVPLR--ARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFE 266
            G T  PG R  P     R +P     +  R   G  G  G     G  E+G +      
Sbjct: 531 PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRG--ERGPQGPP--G 586

Query: 267 LLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGPPEL--EPGL--FEPPPAVVGNLLYPE 322
             G D   G +  +     P +  P G    RG P    +PG+   + PP   GN+    
Sbjct: 587 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM---G 643

Query: 323 PWSVPGCSPTKKSP----LTAPRGGLTLNEPLSPL-YPAAADSPGGEDGRGHLASFAPFF 377
           P   PG    + +P    L  P+G +       P   P  A  PG +   GH        
Sbjct: 644 PQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSG 703

Query: 378 PDCALPPPPPPHQVSYDYSAGYSRTAYSSLWRSDGV--WEGAPGEEG 422
              AL PP P   + Y    G           +DGV   +G+ GE+G
Sbjct: 704 EKGALGPPGPQGPIGYPGPRGVK--------GADGVRGLKGSKGEKG 742



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 92/364 (25%), Positives = 105/364 (28%), Gaps = 87/364 (23%)

Query: 112  PPGPPSPSAADT----PAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAA 167
            P GPP P   D     P +R        T      G   P+    +              
Sbjct: 893  PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE-------- 944

Query: 168  LFDSLRHVPGGAEPAGGEVAAPAAGLGGA----GTGGAGGDVAGPAGATAIPGARKVP-- 221
                 R  PG   P G +    AAG  GA    G  G  G   GPAG    PG R +P  
Sbjct: 945  -----RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK-DGPAGLRGFPGERGLPGA 998

Query: 222  LRARNL--------PPSFFTEPSRAGGGGC----------GPSGPDVSLGDLEKGAEAVE 263
              A  L        PP     P   G  G           GP GP    G  EKGA   +
Sbjct: 999  QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG--EKGAPGEK 1056

Query: 264  FFELLGPDYGAGTEAAVLLAAEPLDVFPAGA---------------------SVLRGPPE 302
                 GP   AG +        P    PAG+                         GPP 
Sbjct: 1057 -----GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG 1111

Query: 303  LEPGLFEP--PPAVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADS 360
              PGL  P   P + G    P P    G    K        G      P  P+       
Sbjct: 1112 -PPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK-----GDEGARGFPGPPGPIGLQGLPG 1165

Query: 361  PGGEDG-RGHLASFAPFFPDCALPPPPPPHQVSYDYSAGYSRTAYSSLWRSDGVWE-GAP 418
            P GE G  G +    P       P PP P        A   +    S+    GV E G P
Sbjct: 1166 PPGEKGENGDVGPMGP-------PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEP 1218

Query: 419  GEEG 422
            GE G
Sbjct: 1219 GEAG 1222



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 101/389 (25%), Positives = 125/389 (32%), Gaps = 103/389 (26%)

Query: 20   GSPDGLGGAFGALDKGCCFEDDETGAPAGALLSGAEG--GDVREATRDLLSFIDSASSNI 77
            G P  +G   G  +KG   E    G P  A + G +G  G+  EA           ++  
Sbjct: 1201 GPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG-------PPGAAGP 1253

Query: 78   KLALDKPGKSKRKVNHRKYLQKQIKRCSGLMG-AAPPGPPSPSAADTPA--KRPLAAPSA 134
              A   PG    K N             G  G   PPG P P+  D     K     P  
Sbjct: 1254 PGAKGPPGDDGPKGNPGPV---------GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1304

Query: 135  PTVAAPAHGKAAP-----RREASQAAAAASLQSRSLAALFDSLRHVPGGAEPAGGEVAAP 189
            P    P+ G+A P     +R    AA A   Q               G    AG E   P
Sbjct: 1305 PGPPGPS-GEAGPPGPPGKRGPPGAAGAEGRQGEK------------GAKGEAGAE--GP 1349

Query: 190  AAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRARNLPPSFFTEPSRAGGGGCGPSGPD 249
                G  G  G  G   GP G   IPG    P+  + LP            G  GP GP 
Sbjct: 1350 PGKTGPVGPQGPAGK-PGPEGLRGIPG----PVGEQGLP---------GAAGQDGPPGP- 1394

Query: 250  VSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGPPELEPGLFE 309
                              +GP    G      L  +P      G+   +G P L  GL  
Sbjct: 1395 ------------------MGPPGLPG------LKGDP------GSKGEKGHPGL-IGLIG 1423

Query: 310  PPPAVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADS-PGGEDGRG 368
            PP    G         +PG   T+ SP     GG+    P  PL P      PG +  +G
Sbjct: 1424 PP----GEQGEKGDRGLPG---TQGSPGAKGDGGIP--GPAGPLGPPGPPGLPGPQGPKG 1474

Query: 369  HLASFAPFFP--DCALPPPP----PPHQV 391
            +  S  P     D  LP PP    PP +V
Sbjct: 1475 NKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1503



 Score = 33.9 bits (76), Expect = 0.29
 Identities = 72/290 (24%), Positives = 94/290 (32%), Gaps = 77/290 (26%)

Query: 106  GLMGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSL 165
            G MG  PPGPP P     P       P  P  +  + G    + E  +A           
Sbjct: 1177 GPMG--PPGPPGPRGPQGP--NGADGPQGPPGSVGSVGGVGEKGEPGEA----------- 1221

Query: 166  AALFDSLRHVPGGAEPAGGEVAAPAAGLGGA-GTGGAGGDVAGPAGATAIPGARKVP--- 221
                       G   P G       AG+GG  G  G  G+ AGP GA   PGA+  P   
Sbjct: 1222 -----------GNPGPPG------EAGVGGPKGERGEKGE-AGPPGAAGPPGAKGPPGDD 1263

Query: 222  -LRARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAV 280
              +    P  F  +P   G    GP+G D   GD  +  +  +     GP   +G     
Sbjct: 1264 GPKGNPGPVGFPGDPGPPGEP--GPAGQDGVGGDKGEDGDPGQ----PGPPGPSG----- 1312

Query: 281  LLAAEPLDVFPAGASVLRGPP--------ELEPGL-----FEPPPAVVGNLLYPEPWSVP 327
                   +  P G    RGPP        + E G       E PP   G +    P   P
Sbjct: 1313 -------EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1365

Query: 328  GCSPTKKSPLTAPRGGLT----LNEPLSPL----YPAAADSPGGEDGRGH 369
            G    +  P      GL      + P  P+     P     PG +  +GH
Sbjct: 1366 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGH 1415


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
           sapiens]
          Length = 1806

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 94/347 (27%), Positives = 119/347 (34%), Gaps = 52/347 (14%)

Query: 106 GLMG-AAPPGPPS----PSAADTPAKRPLAAPSAPTVAAP----AHGKAAPRREASQAAA 156
           GL G   PPG P     P     P    L  P    +  P      G   P   A +A A
Sbjct: 457 GLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQA 516

Query: 157 AASLQSRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGD--------VAGP 208
            A LQ   +A     LR  PG     G     P  G G +G  G  GD        V GP
Sbjct: 517 QAILQQARIA-----LRGPPGPMGLTGRP--GPVGGPGSSGAKGESGDPGPQGPRGVQGP 569

Query: 209 AGATAIPGARKVPLR--ARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFE 266
            G T  PG R  P     R +P     +  R   G  G  G     G  E+G +      
Sbjct: 570 PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRG--ERGPQGPP--G 625

Query: 267 LLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGPPEL--EPGL--FEPPPAVVGNLLYPE 322
             G D   G +  +     P +  P G    RG P    +PG+   + PP   GN+    
Sbjct: 626 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM---G 682

Query: 323 PWSVPGCSPTKKSP----LTAPRGGLTLNEPLSPL-YPAAADSPGGEDGRGHLASFAPFF 377
           P   PG    + +P    L  P+G +       P   P  A  PG +   GH        
Sbjct: 683 PQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSG 742

Query: 378 PDCALPPPPPPHQVSYDYSAGYSRTAYSSLWRSDGV--WEGAPGEEG 422
              AL PP P   + Y    G           +DGV   +G+ GE+G
Sbjct: 743 EKGALGPPGPQGPIGYPGPRGVK--------GADGVRGLKGSKGEKG 781



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 92/364 (25%), Positives = 105/364 (28%), Gaps = 87/364 (23%)

Query: 112  PPGPPSPSAADT----PAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAA 167
            P GPP P   D     P +R        T      G   P+    +              
Sbjct: 932  PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE-------- 983

Query: 168  LFDSLRHVPGGAEPAGGEVAAPAAGLGGA----GTGGAGGDVAGPAGATAIPGARKVP-- 221
                 R  PG   P G +    AAG  GA    G  G  G   GPAG    PG R +P  
Sbjct: 984  -----RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK-DGPAGLRGFPGERGLPGA 1037

Query: 222  LRARNL--------PPSFFTEPSRAGGGGC----------GPSGPDVSLGDLEKGAEAVE 263
              A  L        PP     P   G  G           GP GP    G  EKGA   +
Sbjct: 1038 QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG--EKGAPGEK 1095

Query: 264  FFELLGPDYGAGTEAAVLLAAEPLDVFPAGA---------------------SVLRGPPE 302
                 GP   AG +        P    PAG+                         GPP 
Sbjct: 1096 -----GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG 1150

Query: 303  LEPGLFEP--PPAVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADS 360
              PGL  P   P + G    P P    G    K        G      P  P+       
Sbjct: 1151 -PPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK-----GDEGARGFPGPPGPIGLQGLPG 1204

Query: 361  PGGEDG-RGHLASFAPFFPDCALPPPPPPHQVSYDYSAGYSRTAYSSLWRSDGVWE-GAP 418
            P GE G  G +    P       P PP P        A   +    S+    GV E G P
Sbjct: 1205 PPGEKGENGDVGPMGP-------PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEP 1257

Query: 419  GEEG 422
            GE G
Sbjct: 1258 GEAG 1261



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 101/389 (25%), Positives = 125/389 (32%), Gaps = 103/389 (26%)

Query: 20   GSPDGLGGAFGALDKGCCFEDDETGAPAGALLSGAEG--GDVREATRDLLSFIDSASSNI 77
            G P  +G   G  +KG   E    G P  A + G +G  G+  EA           ++  
Sbjct: 1240 GPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG-------PPGAAGP 1292

Query: 78   KLALDKPGKSKRKVNHRKYLQKQIKRCSGLMG-AAPPGPPSPSAADTPA--KRPLAAPSA 134
              A   PG    K N             G  G   PPG P P+  D     K     P  
Sbjct: 1293 PGAKGPPGDDGPKGNPGPV---------GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1343

Query: 135  PTVAAPAHGKAAP-----RREASQAAAAASLQSRSLAALFDSLRHVPGGAEPAGGEVAAP 189
            P    P+ G+A P     +R    AA A   Q               G    AG E   P
Sbjct: 1344 PGPPGPS-GEAGPPGPPGKRGPPGAAGAEGRQGEK------------GAKGEAGAE--GP 1388

Query: 190  AAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRARNLPPSFFTEPSRAGGGGCGPSGPD 249
                G  G  G  G   GP G   IPG    P+  + LP            G  GP GP 
Sbjct: 1389 PGKTGPVGPQGPAGK-PGPEGLRGIPG----PVGEQGLP---------GAAGQDGPPGP- 1433

Query: 250  VSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGPPELEPGLFE 309
                              +GP    G      L  +P      G+   +G P L  GL  
Sbjct: 1434 ------------------MGPPGLPG------LKGDP------GSKGEKGHPGL-IGLIG 1462

Query: 310  PPPAVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADS-PGGEDGRG 368
            PP    G         +PG   T+ SP     GG+    P  PL P      PG +  +G
Sbjct: 1463 PP----GEQGEKGDRGLPG---TQGSPGAKGDGGIP--GPAGPLGPPGPPGLPGPQGPKG 1513

Query: 369  HLASFAPFFP--DCALPPPP----PPHQV 391
            +  S  P     D  LP PP    PP +V
Sbjct: 1514 NKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1542



 Score = 33.9 bits (76), Expect = 0.29
 Identities = 72/290 (24%), Positives = 94/290 (32%), Gaps = 77/290 (26%)

Query: 106  GLMGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSL 165
            G MG  PPGPP P     P       P  P  +  + G    + E  +A           
Sbjct: 1216 GPMG--PPGPPGPRGPQGP--NGADGPQGPPGSVGSVGGVGEKGEPGEA----------- 1260

Query: 166  AALFDSLRHVPGGAEPAGGEVAAPAAGLGGA-GTGGAGGDVAGPAGATAIPGARKVP--- 221
                       G   P G       AG+GG  G  G  G+ AGP GA   PGA+  P   
Sbjct: 1261 -----------GNPGPPG------EAGVGGPKGERGEKGE-AGPPGAAGPPGAKGPPGDD 1302

Query: 222  -LRARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAV 280
              +    P  F  +P   G    GP+G D   GD  +  +  +     GP   +G     
Sbjct: 1303 GPKGNPGPVGFPGDPGPPGEP--GPAGQDGVGGDKGEDGDPGQ----PGPPGPSG----- 1351

Query: 281  LLAAEPLDVFPAGASVLRGPP--------ELEPGL-----FEPPPAVVGNLLYPEPWSVP 327
                   +  P G    RGPP        + E G       E PP   G +    P   P
Sbjct: 1352 -------EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1404

Query: 328  GCSPTKKSPLTAPRGGLT----LNEPLSPL----YPAAADSPGGEDGRGH 369
            G    +  P      GL      + P  P+     P     PG +  +GH
Sbjct: 1405 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGH 1454


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 104/376 (27%), Positives = 126/376 (33%), Gaps = 74/376 (19%)

Query: 12   PFVPFGFGGSPDGLGGAFGALDKGCCFEDDETGAPAGALLSGAEGGDVREATRDLLSFID 71
            P  P G  G+P G  GA G  D G        GAP    + G  G       +      D
Sbjct: 693  PAGPRGANGAP-GNDGAKG--DAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKG-----D 744

Query: 72   SASSNIKLALDKPGKSKRKVNHRKYLQKQIKRCSGLMGAAPPGPPSPSAADTPAKRPLAA 131
               +  K A   PGK   +               GL G  P GPP P+ A  P  +  + 
Sbjct: 745  RGDAGPKGADGSPGKDGVR---------------GLTG--PIGPPGPAGA--PGDKGESG 785

Query: 132  PSAPTVAAPAHGKAAPRREASQAAAA-------------ASLQSRSLAALFDSLRHVPGG 178
            PS P     A G    R E      A             A  +     A  D+    PG 
Sbjct: 786  PSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDA--GPPGP 843

Query: 179  AEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRARNLPPSFFTEPSRA 238
            A PAG     P   +G  G  GA G  AGP GAT  PGA       R  PP     PS  
Sbjct: 844  AGPAGPP--GPIGNVGAPGAKGARGS-AGPPGATGFPGAA-----GRVGPPG----PSGN 891

Query: 239  GG--GGCGPSGPDVSLGDLEKGAEAVEFFEL-----LGPDYGAGTEAAVLLAAEPLDVFP 291
             G  G  GP+G +   G   +   A    E+      GP    G+  A   A  P    P
Sbjct: 892  AGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGP 951

Query: 292  AGASVLRGPPELEPGLFEPPPAVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLS 351
             G +  RG   L        P   G   +P    +PG  P+ +     P G      P  
Sbjct: 952  QGIAGQRGVVGL--------PGQRGERGFP---GLPG--PSGEPGKQGPSGASGERGPPG 998

Query: 352  PLYPAAADSPGGEDGR 367
            P+ P     P GE GR
Sbjct: 999  PMGPPGLAGPPGESGR 1014



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 92/354 (25%), Positives = 113/354 (31%), Gaps = 57/354 (16%)

Query: 22   PDGLGGAFGALDKGCCFEDDETGAPAGALLSGAEGGDVREATRDLLSFIDSASSNIKLAL 81
            P G  G  GA  +G   +  E G P  A  +G  G D +   +      +   +  K   
Sbjct: 786  PSGPAGPTGA--RGAPGDRGEPGPPGPAGFAGPPGADGQPGAKG-----EPGDAGAKGDA 838

Query: 82   DKPGKSKRKVNHRKYLQKQIKRCSGLMGAA-PPG----PPSPSAADTPAKRPLAAPSAPT 136
              PG +                  G  G+A PPG    P +      P     A P  P 
Sbjct: 839  GPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPP 898

Query: 137  VAAPAHGKAAPRREASQAAAAASLQSRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGGA 196
              A   G   PR E   A     +               PG   PAG + +  A G  GA
Sbjct: 899  GPAGKEGGKGPRGETGPAGRPGEVGP-------------PGPPGPAGEKGSPGADGPAGA 945

Query: 197  -GTGGAGGDVAGPAGATAIPGARKVPLRARNLP--PSFFTEPSRAG-GGGCGPSGPDVSL 252
             GT G  G +AG  G   +PG R      R  P  P    EP + G  G  G  GP   +
Sbjct: 946  PGTPGPQG-IAGQRGVVGLPGQR----GERGFPGLPGPSGEPGKQGPSGASGERGPPGPM 1000

Query: 253  GDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGPPELEPGLFEPPP 312
            G             L GP   +G E A      P      GA   RG    E G   PP 
Sbjct: 1001 GPP----------GLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRG----ETGPAGPPG 1046

Query: 313  AVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADSPGGEDG 366
            A       P     PG  P   +  +  RG      P  P+ P  A  P G  G
Sbjct: 1047 A-------PGAPGAPG--PVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQG 1091



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 87/296 (29%), Positives = 93/296 (31%), Gaps = 63/296 (21%)

Query: 106 GLMGAA-PPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRS 164
           G  GAA PPGP  P           A P     A  A G+A P+                
Sbjct: 326 GATGAAGPPGPTGP-----------AGPPGFPGAVGAKGEAGPQGPRGSEGP-------- 366

Query: 165 LAALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGP--AGATAIPGARKVPL 222
                  +R  PG   PAG   A PA   G  G  GA G    P  AGA   PGAR    
Sbjct: 367 -----QGVRGEPGPPGPAGA--AGPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR---- 415

Query: 223 RARNLPPSFFTEPSRAGG--GGCGPSGPDVSLGDL----EKGAEAVEFFELLGPDYGAGT 276
                 PS    P    G  G  G  G   S GD     E G   V+     GP   AG 
Sbjct: 416 -----GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQ-----GPPGPAGE 465

Query: 277 EAAVLLAAEPLDVFPAGASVLRGPPELEPGL----FEPPPAVVGNLLYPEPWSVPGCSPT 332
           E       EP      G + L GPP    G     F     V G          PG +  
Sbjct: 466 EGKRGARGEP------GPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGP 519

Query: 333 KKSPLTAPRGGLTLNEPLSPLYPAAADSPGGEDGRGHLASFAPFFPDCALPPPPPP 388
           K SP  A R G    E   P       SPG     G      P   D    PP PP
Sbjct: 520 KGSPGEAGRPG----EAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPP 571



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 75/276 (27%), Positives = 100/276 (36%), Gaps = 39/276 (14%)

Query: 102 KRCSGLMGAAPP----GPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAA 157
           K  +G  G+  P    GPP P+  D     P   P      A   G   P+  A +   A
Sbjct: 538 KGLTGSPGSPGPDGKTGPPGPAGQDGRPGPP--GPPGARGQAGVMGFPGPKGAAGEPGKA 595

Query: 158 ASLQSRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGG-AGTGGAGGDVAGPAGATAIPG 216
                         +   PG   PAG +  A A G  G AG  G  G+  GPAG+   PG
Sbjct: 596 GER----------GVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGE-QGPAGS---PG 641

Query: 217 ARKVPLRARNLPPSFFTEPSRAG-GGGCGPSGPDVSLGDL----EKGAEAVEFFELLGPD 271
            + +P  A   PP    +P   G  G  G  GP  + G+     E+G +        GP 
Sbjct: 642 FQGLPGPAG--PPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPP-----GPA 694

Query: 272 YGAGTEAAVLLAAEPLDVFPAGASVLRGPPELEPGLFEPPPAVVGNLLYPEPWSVPGCSP 331
              G   A        D    GA   +G P L+ G+    P   G    P P    G + 
Sbjct: 695 GPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQ-GM----PGERGAAGLPGPKGDRGDAG 749

Query: 332 TKKSPLTAPRGGLT-LNEPLSPLYPAAADSPGGEDG 366
            K +  +  + G+  L  P+ P  PA A    GE G
Sbjct: 750 PKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESG 785



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 61/221 (27%), Positives = 74/221 (33%), Gaps = 46/221 (20%)

Query: 112 PPGPPSPSAADTP-----AKRPLAAPSAPTV--------------AAPAHGKAAPRREAS 152
           PPGP  P  A+       AK    AP AP                AA   G    R +A 
Sbjct: 690 PPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAG 749

Query: 153 QAAAAASLQSRSLAALFDSLRHV-PGGAEPAGGEVAAPAAGLGGAGTGGAGGD------- 204
              A  S     +  L   +    P GA    GE + P+   G  G  GA GD       
Sbjct: 750 PKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGE-SGPSGPAGPTGARGAPGDRGEPGPP 808

Query: 205 ----VAGPAGATAIPGARKVPLRARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAE 260
                AGP GA   PGA+  P  A         +      G  GP+GP   +G++  GA 
Sbjct: 809 GPAGFAGPPGADGQPGAKGEPGDAG-------AKGDAGPPGPAGPAGPPGPIGNV--GAP 859

Query: 261 AVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGPP 301
             +     G    AG   A         V P G S   GPP
Sbjct: 860 GAK-----GARGSAGPPGATGFPGAAGRVGPPGPSGNAGPP 895



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 85/315 (26%), Positives = 96/315 (30%), Gaps = 77/315 (24%)

Query: 105 SGLMGA-APPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSR 163
           SG MG   PPGPP  +  D  A +P   P       P   +  P          A L   
Sbjct: 214 SGPMGPRGPPGPPGKNGDDGEAGKP-GRPGERGPPGPQGARGLP--------GTAGLPGM 264

Query: 164 SLAALFDSLRHVPGGAEPAG--------GEVAAP--------------------AAGLGG 195
                F  L    G A PAG        GE  AP                    A   G 
Sbjct: 265 KGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGN 324

Query: 196 AGTGGAGGDVA--GPAGATAIPGARKVPLRARNLPPSFFTEPSRAGGGGCGPSGPDVSLG 253
            G  GA G     GPAG    PGA      A    P   +E  +   G  GP GP  + G
Sbjct: 325 DGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPR-GSEGPQGVRGEPGPPGPAGAAG 383

Query: 254 DL-EKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGPPELEPGLFEPPP 312
                GA+        G     G   A  +A  P   FP GA    GP    PG    PP
Sbjct: 384 PAGNPGAD--------GQPGAKGANGAPGIAGAP--GFP-GARGPSGPQ--GPG---GPP 427

Query: 313 AVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADSPGGEDG-RGHLA 371
              GN   P      G +  K  P               P+       P GE+G RG   
Sbjct: 428 GPKGNSGEPGAPGSKGDTGAKGEP--------------GPVGVQGPPGPAGEEGKRGARG 473

Query: 372 SFAPFFPDCALPPPP 386
              P      LP PP
Sbjct: 474 EPGP----TGLPGPP 484


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 70/271 (25%), Positives = 93/271 (34%), Gaps = 32/271 (11%)

Query: 106 GLMGAAPPGPPSPSA---ADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQS 162
           G  GAAP  PP+  A      P +    +P  P V A     AA  R   + +A +    
Sbjct: 81  GAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPV 140

Query: 163 RSLAALFDSLRHVPGG-AEPAGGEVAAPAAGLG-----GAGTGGAGGDVAGPAGATAIPG 216
            + AA+       P G A+PAG    A  AG G     G G G   G  AGP  A  + G
Sbjct: 141 PAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNG 200

Query: 217 ARKVPLRARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGT 276
           +  +            +  + A       +GP  +L  L K A      +   P  GA  
Sbjct: 201 SAAL----------LNSHHAAAPAVSLVNNGP-AALLPLPKPAAPGTVIQ-TPPFVGAAA 248

Query: 277 EAAVLLAAEPLDVFPAGASVLRGPPELEPGLFEPPPAVVGNLLYPEPWSVPGCSPTKKSP 336
             A    + P    PA  +    PP   P     PP          P   P  +P    P
Sbjct: 249 PPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPG--------HPAGPPTAAPAVPPP 300

Query: 337 LTAPRGGLTLNEPLSPLYPAAADSPGGEDGR 367
             A  GG   +   +P    AA  P G  G+
Sbjct: 301 AAAQNGG---SAGAAPAPAPAAGGPAGVSGQ 328



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 87/316 (27%), Positives = 104/316 (32%), Gaps = 51/316 (16%)

Query: 109 GAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAAL 168
           GAA  GP +P+        P AAP  P       G   P+R     +    L     A  
Sbjct: 69  GAAGAGPAAPAEG-----APGAAPEPPPAGRARPGGGGPQR-PGPPSPRRPLVPAGPAPP 122

Query: 169 FDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRARNLP 228
              LR  P G+  AG     PAA    AG   A    A PAG  A+  AR  P       
Sbjct: 123 AAKLRPPPEGS--AGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAAL-AARAGP------- 172

Query: 229 PSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLD 288
                 P    G G GP GP    G     A+ +     L   + A   A  L+   P  
Sbjct: 173 -----GPGPGPGPGPGP-GPGKPAG--PGAAQTLNGSAALLNSHHAAAPAVSLVNNGP-- 222

Query: 289 VFPAGASVLRGPPELEPGLFEPPPAVVGNLLYPEPWS-VPGCSPTKKSPLTAPRGGLTLN 347
                A++L  P    PG     P  VG    P P +  P  +P   +P  AP       
Sbjct: 223 -----AALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAP------- 270

Query: 348 EPLSPLYPAAADSPGGEDGRGHLASFAPFFPDCALPPPPPPHQVSYDYSAGYSRTAYSSL 407
            P  P  PA    P G           P  P  A P  PPP       SAG +     + 
Sbjct: 271 -PPPPPAPATLARPPGH----------PAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAA 319

Query: 408 WRSDGVWEGAPGEEGA 423
               GV  G PG   A
Sbjct: 320 GGPAGV-SGQPGPGAA 334



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 78/278 (28%), Positives = 94/278 (33%), Gaps = 66/278 (23%)

Query: 138 AAPAHGKAAPRREASQAAAAASLQSRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGGAG 197
           +A  H   APR    +AAAA +L +  ++         P GA  AG   AAPA G  GA 
Sbjct: 36  SAAHHHHLAPRTPEVRAAAAGALGNHVVSGS-------PAGA--AGAGPAAPAEGAPGAA 86

Query: 198 T----------GGAGGDVAGPAGATAIPGARKVPLRARNLPPSFFTEPSRAGGGG-CGP- 245
                      GG G    GP      P  R+  + A   PP+    P   G  G C P 
Sbjct: 87  PEPPPAGRARPGGGGPQRPGP------PSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPV 140

Query: 246 -------SGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAG---AS 295
                  +GP+ +     K A         GP  G G          P    PAG   A 
Sbjct: 141 PAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPG----PGPGPGKPAGPGAAQ 196

Query: 296 VLRGPPELEPGLFEPPPAVVGNLLYPEPWSVPGCSPTKKSPLTAPRG-GLTLNEP----- 349
            L G   L        PAV          S+    P    PL  P   G  +  P     
Sbjct: 197 TLNGSAALLNSHHAAAPAV----------SLVNNGPAALLPLPKPAAPGTVIQTPPFVGA 246

Query: 350 LSPLYPAAADSPGGEDGRGHLASFAPFFPDCALPPPPP 387
            +P  PAA   P         A+ AP  P  A PPPPP
Sbjct: 247 AAPPAPAAPSPP---------AAPAPAAPAAAPPPPPP 275



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 39/108 (36%), Positives = 42/108 (38%), Gaps = 18/108 (16%)

Query: 110 AAPPGP--PSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAA 167
           AAPP P  PSP AA  PA  P AAP  P   APA     P   A    AA ++       
Sbjct: 247 AAPPAPAAPSPPAAPAPA-APAAAPPPPP-PAPATLARPPGHPAGPPTAAPAVPP----- 299

Query: 168 LFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIP 215
                   P  A+  G   AAPA      G  G  G   GP  A A P
Sbjct: 300 --------PAAAQNGGSAGAAPAPAPAAGGPAGVSGQ-PGPGAAAAAP 338



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 37/109 (33%), Positives = 44/109 (40%), Gaps = 18/109 (16%)

Query: 110 AAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALF 169
           AAP  P +P+ A   A  P   P+  T+A P    A P   A      A+ Q+   A   
Sbjct: 253 AAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSA--- 309

Query: 170 DSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGAR 218
                   GA PA     APAAG G AG  G  G   G A A   PG +
Sbjct: 310 --------GAAPA----PAPAAG-GPAGVSGQPG--PGAAAAAPAPGVK 343



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 34/117 (29%), Positives = 44/117 (37%), Gaps = 6/117 (5%)

Query: 112 PPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALFDS 171
           P GPP+ + A  P        SA    APA     P   + Q    A+  + +     +S
Sbjct: 287 PAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAES 346

Query: 172 LRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRARNLP 228
            + V   A PA   +AA     G A T  A   V GP    A+P    VP  A   P
Sbjct: 347 PKRVVQAAPPAAQTLAAS----GPAST--AASMVIGPTMQGALPSPAAVPPPAPGTP 397


>gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens]
          Length = 1047

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 60/179 (33%), Positives = 75/179 (41%), Gaps = 19/179 (10%)

Query: 109 GAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAAL 168
           GA   G  + S+A  PA   +  P+A  VAA  +        A      A+L S  L A 
Sbjct: 17  GAGGGGAAAGSSA-YPAVCRVKIPAALPVAAAPYPGLVETGVAGTLGGGAALGSEFLGA- 74

Query: 169 FDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRARNLP 228
             S+    GGA   GG     AAG+ GA  G AG  VAGP+G  A+            LP
Sbjct: 75  -GSVAGALGGAGLTGG---GTAAGVAGAAAGVAGAAVAGPSGDMAL----------TKLP 120

Query: 229 PSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELL-GPDYGAGTEAAVLLAAEP 286
            S   E +   GGG  P  P   L  L  G   V+  + L GP+Y    E A+ L A P
Sbjct: 121 TSLLAE-TLGPGGGFPPLPPPPYLPPLGAGLGTVDEGDSLDGPEY-EEEEVAIPLTAPP 177



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 50/164 (30%), Positives = 64/164 (39%), Gaps = 15/164 (9%)

Query: 179 AEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRARNLPPSFFTEPSRA 238
           A  AG E   P     GAG GGA       AG++A P   +V + A  LP +    P   
Sbjct: 3   AAEAGSEEGGPVT--AGAGGGGAA------AGSSAYPAVCRVKIPAA-LPVAAAPYPGLV 53

Query: 239 GGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLR 298
             G  G  G   +LG    GA +V          G GT A V  AA  +    AGA+V  
Sbjct: 54  ETGVAGTLGGGAALGSEFLGAGSVAGALGGAGLTGGGTAAGVAGAAAGV----AGAAV-- 107

Query: 299 GPPELEPGLFEPPPAVVGNLLYPEPWSVPGCSPTKKSPLTAPRG 342
             P  +  L + P +++   L P     P   P    PL A  G
Sbjct: 108 AGPSGDMALTKLPTSLLAETLGPGGGFPPLPPPPYLPPLGAGLG 151


>gi|239752280 PREDICTED: similar to family with sequence similarity
           48, member B2 [Homo sapiens]
          Length = 779

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 63/217 (29%), Positives = 84/217 (38%), Gaps = 31/217 (14%)

Query: 100 QIKRCSGLMGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKA-----APRREASQA 154
           Q+   SG + +    PP    A +P KRP  A +AP VAA A   A     AP   A+  
Sbjct: 428 QLPSSSGKISSGNSFPPQQ--AGSPLKRPFPA-AAPAVAAAAPAPAPAPAAAPALAAAAV 484

Query: 155 AAAA-----SLQSRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPA 209
           AAAA     S   +    L  + R  P    P      APA  +    TG    +V GP 
Sbjct: 485 AAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPV 544

Query: 210 GATAIPGARKVPLRARNLPPSFFTEPSRAGGGGCGPSG---PDVSLGDLEKGAEAVEFFE 266
               + G    P++A   P S    P+   G G   SG   PD   G ++  + A   F 
Sbjct: 545 RGAQVLGCSFKPVQA---PGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFF 601

Query: 267 LLGPDYGAGTEAAVLLAAEPLDV-FPAGASVLRGPPE 302
           L  P+              PL +  P G +VL GP +
Sbjct: 602 LNTPE-----------GLRPLTLQVPQGWAVLTGPQQ 627


>gi|210032463 family with sequence similarity 48, member B2 [Homo
           sapiens]
          Length = 817

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 63/217 (29%), Positives = 84/217 (38%), Gaps = 31/217 (14%)

Query: 100 QIKRCSGLMGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKA-----APRREASQA 154
           Q+   SG + +    PP    A +P KRP  A +AP VAA A   A     AP   A+  
Sbjct: 466 QLPSSSGKISSGNSFPPQQ--AGSPLKRPFPA-AAPAVAAAAPAPAPAPAAAPALAAAAV 522

Query: 155 AAAA-----SLQSRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPA 209
           AAAA     S   +    L  + R  P    P      APA  +    TG    +V GP 
Sbjct: 523 AAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPV 582

Query: 210 GATAIPGARKVPLRARNLPPSFFTEPSRAGGGGCGPSG---PDVSLGDLEKGAEAVEFFE 266
               + G    P++A   P S    P+   G G   SG   PD   G ++  + A   F 
Sbjct: 583 RGAQVLGCSFKPVQA---PGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFF 639

Query: 267 LLGPDYGAGTEAAVLLAAEPLDV-FPAGASVLRGPPE 302
           L  P+              PL +  P G +VL GP +
Sbjct: 640 LNTPE-----------GLRPLTLQVPQGWAVLTGPQQ 665


>gi|239757043 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 996

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 97/338 (28%), Positives = 117/338 (34%), Gaps = 74/338 (21%)

Query: 107 LMGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPR----REASQAAAAASLQS 162
           L+GA PP PP P             P A    AP      PR     ++ Q AA  +  S
Sbjct: 281 LLGAPPPPPPPPP------------PLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAAS 328

Query: 163 RSLAALFDSLRHVPGGAEPAGGEVAAP-AAGLG-GAGTG-GAGGDVAGPAGATAIP---- 215
            S AA   S+    GGA   GG       AG+G GAG G GAG    GP     IP    
Sbjct: 329 LSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSK 388

Query: 216 ----GARKVPLRARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPD 271
               G  +       L P  +T P+ A            +     K  +A    E LG  
Sbjct: 389 GSFGGVLQKFPGCGGLFPHPYTFPAAA-----------AAFSLCHKKEDAGAAAEALG-- 435

Query: 272 YGAGTEAAVLLAAEPLDVFPAGASVLRGPPELEPGLFEP-----PPAVVGNLLYPEPWSV 326
            GAG   A    A P     AG S L  P   +   + P     PP   G L  P     
Sbjct: 436 -GAGAGGA---GAAP----KAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQP 487

Query: 327 PGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAAD--SPGGEDGRGHLASFAPFFPDCALPP 384
           P   P   S L     G  L E  + L  A  D   PGG  G            + A PP
Sbjct: 488 P---PQPPSAL-----GCALGESPALLRQAFLDLAEPGGAAGSA----------EAAPPP 529

Query: 385 PPPPHQVSYDYSAGYSRTAYSSLWRSDGVWEGAPGEEG 422
             PP  V+    +G    A  +  R D ++E  PG  G
Sbjct: 530 GQPPQVVANGPGSGPPPPAGGAGSR-DALFESPPGGSG 566



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 29/98 (29%), Positives = 33/98 (33%), Gaps = 16/98 (16%)

Query: 116 PSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALFDSLRHV 175
           P  +A    A  P   P       P  G   P   A            S  ALF+S    
Sbjct: 516 PGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAG-----------SRDALFESPPGG 564

Query: 176 PGG-----AEPAGGEVAAPAAGLGGAGTGGAGGDVAGP 208
            GG     + P    VAA  AG   AG+G AG  V  P
Sbjct: 565 SGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAP 602


>gi|239751555 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 97/338 (28%), Positives = 117/338 (34%), Gaps = 74/338 (21%)

Query: 107 LMGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPR----REASQAAAAASLQS 162
           L+GA PP PP P             P A    AP      PR     ++ Q AA  +  S
Sbjct: 281 LLGAPPPPPPPPP------------PLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAAS 328

Query: 163 RSLAALFDSLRHVPGGAEPAGGEVAAP-AAGLG-GAGTG-GAGGDVAGPAGATAIP---- 215
            S AA   S+    GGA   GG       AG+G GAG G GAG    GP     IP    
Sbjct: 329 LSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSK 388

Query: 216 ----GARKVPLRARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPD 271
               G  +       L P  +T P+ A            +     K  +A    E LG  
Sbjct: 389 GSFGGVLQKFPGCGGLFPHPYTFPAAA-----------AAFSLCHKKEDAGAAAEALG-- 435

Query: 272 YGAGTEAAVLLAAEPLDVFPAGASVLRGPPELEPGLFEP-----PPAVVGNLLYPEPWSV 326
            GAG   A    A P     AG S L  P   +   + P     PP   G L  P     
Sbjct: 436 -GAGAGGA---GAAP----KAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQP 487

Query: 327 PGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAAD--SPGGEDGRGHLASFAPFFPDCALPP 384
           P   P   S L     G  L E  + L  A  D   PGG  G            + A PP
Sbjct: 488 P---PQPPSAL-----GCALGESPALLRQAFLDLAEPGGAAGSA----------EAAPPP 529

Query: 385 PPPPHQVSYDYSAGYSRTAYSSLWRSDGVWEGAPGEEG 422
             PP  V+    +G    A  +  R D ++E  PG  G
Sbjct: 530 GQPPQVVANGPGSGPPPPAGGAGSR-DALFESPPGGSG 566



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 29/98 (29%), Positives = 33/98 (33%), Gaps = 16/98 (16%)

Query: 116 PSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALFDSLRHV 175
           P  +A    A  P   P       P  G   P   A            S  ALF+S    
Sbjct: 516 PGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAG-----------SRDALFESPPGG 564

Query: 176 PGG-----AEPAGGEVAAPAAGLGGAGTGGAGGDVAGP 208
            GG     + P    VAA  AG   AG+G AG  V  P
Sbjct: 565 SGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAP 602


>gi|239746067 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 97/338 (28%), Positives = 117/338 (34%), Gaps = 74/338 (21%)

Query: 107 LMGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPR----REASQAAAAASLQS 162
           L+GA PP PP P             P A    AP      PR     ++ Q AA  +  S
Sbjct: 281 LLGAPPPPPPPPP------------PLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAAS 328

Query: 163 RSLAALFDSLRHVPGGAEPAGGEVAAP-AAGLG-GAGTG-GAGGDVAGPAGATAIP---- 215
            S AA   S+    GGA   GG       AG+G GAG G GAG    GP     IP    
Sbjct: 329 LSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSK 388

Query: 216 ----GARKVPLRARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPD 271
               G  +       L P  +T P+ A            +     K  +A    E LG  
Sbjct: 389 GSFGGVLQKFPGCGGLFPHPYTFPAAA-----------AAFSLCHKKEDAGAAAEALG-- 435

Query: 272 YGAGTEAAVLLAAEPLDVFPAGASVLRGPPELEPGLFEP-----PPAVVGNLLYPEPWSV 326
            GAG   A    A P     AG S L  P   +   + P     PP   G L  P     
Sbjct: 436 -GAGAGGA---GAAP----KAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQP 487

Query: 327 PGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAAD--SPGGEDGRGHLASFAPFFPDCALPP 384
           P   P   S L     G  L E  + L  A  D   PGG  G            + A PP
Sbjct: 488 P---PQPPSAL-----GCALGESPALLRQAFLDLAEPGGAAGSA----------EAAPPP 529

Query: 385 PPPPHQVSYDYSAGYSRTAYSSLWRSDGVWEGAPGEEG 422
             PP  V+    +G    A  +  R D ++E  PG  G
Sbjct: 530 GQPPQVVANGPGSGPPPPAGGAGSR-DALFESPPGGSG 566



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 29/98 (29%), Positives = 33/98 (33%), Gaps = 16/98 (16%)

Query: 116 PSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALFDSLRHV 175
           P  +A    A  P   P       P  G   P   A            S  ALF+S    
Sbjct: 516 PGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAG-----------SRDALFESPPGG 564

Query: 176 PGG-----AEPAGGEVAAPAAGLGGAGTGGAGGDVAGP 208
            GG     + P    VAA  AG   AG+G AG  V  P
Sbjct: 565 SGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAP 602


>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
          Length = 887

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 58/200 (29%), Positives = 77/200 (38%), Gaps = 19/200 (9%)

Query: 110 AAPPGPPSPSAADTPAKRPLAAPS----APTVAAPAHGKAAPRREASQAAAAASLQSRSL 165
           AA    P+ +AA  PA    AAP+    A    APA   A     A+ A+AA S   +  
Sbjct: 514 AAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPS 573

Query: 166 AALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRAR 225
             L  + R  P    P      APA  L    TG    +V GP       G+   P++A 
Sbjct: 574 VPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQA- 632

Query: 226 NLPPSFFTEPSRAGGGGCGPSG---PDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLL 282
             P S    P+   G     SG   PD   G ++  + A   F L  P+   G     LL
Sbjct: 633 --PGSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAPLQFFLNTPE---GLRPLTLL 687

Query: 283 AAEPLDVFPAGASVLRGPPE 302
                   P G++VL GP +
Sbjct: 688 QV------PQGSAVLTGPQQ 701



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 50/185 (27%), Positives = 77/185 (41%), Gaps = 11/185 (5%)

Query: 100 QIKRCSGLMGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAAS 159
           Q+   SG + +    PP    A +P KRP +A +A  +AA A   AA    A+ AA A +
Sbjct: 466 QLPSSSGKISSGNSFPPQQ--AGSPLKRPFSAAAA--IAAAAAAAAAAAAAAAAAAPAPA 521

Query: 160 LQSRSLAALFDSLR-HVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGAR 218
           L + +  AL  +    +   A PA    AAPA     A    A    +       I  +R
Sbjct: 522 LAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASR 581

Query: 219 KVPLRARNLPPSFFTEPSRAGGGGCGPSG-PDVSLGDLEKGAEAV--EFFELLGPDYGAG 275
             P      PP+ F + + A     G +G   +++    +GA+A+   F  +  P  GA 
Sbjct: 582 PCPAAQ---PPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAP 638

Query: 276 TEAAV 280
             A +
Sbjct: 639 APAGI 643


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 80/301 (26%), Positives = 99/301 (32%), Gaps = 56/301 (18%)

Query: 113  PGPPSPSAADTP-AKRPLA------------APSAPTVAAPAHGKAAPRREASQAAAAAS 159
            P PPSP  A TP A  PL+             PS   +  P  G A P  + + A +  S
Sbjct: 856  PTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS 915

Query: 160  LQSRSLAALFDSLRHVPGGAEPAGG---EVAAPAAGLGGAGTGGAGGDVAGPAGATAIP- 215
              S   A    + + +P    P G      A P +  GG  T         PA     P 
Sbjct: 916  -SSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPK 974

Query: 216  GARKVPLRARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAG 275
            G    P       P   T PS  G    GP+ P        KGA        + P    G
Sbjct: 975  GGPATPSPKGAPTPPAATPPSPKG----GPATPS------PKGAPTP---PAVTPPSPKG 1021

Query: 276  TEAAVLLAAEPLDVFPAGASVLRGPPELEPGLFEPPPAVVGNLLYPEPWSVPGCSPTKKS 335
            + AA          FP GAS    PP   P   +  PA       P P    G   T  +
Sbjct: 1022 SPAAT--------PFPKGAST---PPAATPPSPKGSPAAT-----PLP---KGAPTTPAA 1062

Query: 336  PLTAPRGGLTLNEPLSPLYPAAADSPGGEDGRGHLASFAPFFPDCALPPPP------PPH 389
             L +P+GG           P AA  P  + G    +      P  A PP P      PPH
Sbjct: 1063 TLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPH 1122

Query: 390  Q 390
            +
Sbjct: 1123 K 1123



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 82/315 (26%), Positives = 99/315 (31%), Gaps = 46/315 (14%)

Query: 111  APPGPPSPSAADTPAKR-------PLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSR 163
            +P G P+P AA  P+ +       P  AP+ P V  P+  K +P        A     S 
Sbjct: 981  SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS-PKGSPAATPFPKGA-----ST 1034

Query: 164  SLAALFDSLRHVPGGAEPAGGEVAAPAAGL----GGAGTGGAGGDVAGPA-------GAT 212
              AA   S +  P       G    PAA L    GG  T    G    PA       G  
Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094

Query: 213  AIPGARKVPLRARNLPPS---FFTEPSRAGGGGCGPSGPDVSLGDL----EKGAEAVEFF 265
            A P  +  P+     PPS       P   G      + P    G L     KGA      
Sbjct: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1154

Query: 266  ELLGPDYGAGTE----AAVLLAAEPLDVFPAGASVLRGPPELEPGLFEPPPAVVGNLLYP 321
                P  G  T     A    AA P    P G      P          PP+  G L  P
Sbjct: 1155 TPPSPKGGLATPPPKGAPTTPAATPPS--PKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212

Query: 322  EPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADSPGGEDGRGHLASFAPFFPDCA 381
             P   P  +P    P  +P+GGL    P       AA  P  + G           P  A
Sbjct: 1213 SPKGAP-TTPAATPP--SPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAA 1269

Query: 382  LPP------PPPPHQ 390
             PP        PPH+
Sbjct: 1270 TPPSLKGGLATPPHK 1284



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 76/287 (26%), Positives = 93/287 (32%), Gaps = 32/287 (11%)

Query: 110  AAPPGPPSPSAADTPAKRPL--AAPSAP--TVAAPAHGKAAPRREASQAAAAASLQSRSL 165
            + PP    PS   +PA  PL   AP+ P  T+ +P  G A P  + +    AA+  S   
Sbjct: 1033 STPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG 1092

Query: 166  AALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIP--GARKVPLR 223
                 S +  P    PA    A P +  GG  T    G    PA     P  G    P +
Sbjct: 1093 GPATPSPKGAP--MPPA----ATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPK 1146

Query: 224  ARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTE----AA 279
                 P+  T PS  GG    P           KGA          P  G  T     A 
Sbjct: 1147 GAPTTPA-ATPPSPKGGLATPP----------PKGAPTTPAATPPSPKGGLATPSPKGAP 1195

Query: 280  VLLAAEPLDVFPAGASVLRGPPELEPGLFEPPPAVVGNLLYPEPWSVPGCSPTKKSPLTA 339
               AA P    P G      P          PP+  G L  P P   P  +P    P  +
Sbjct: 1196 TTPAATPPS--PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP-TTPAATPP--S 1250

Query: 340  PRGGLTLNEPLSPLYPAAADSPGGEDGRGHLASFAPFFPDCALPPPP 386
            P+GG     P     P AA  P  + G           P    PP P
Sbjct: 1251 PKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP 1297



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 75/291 (25%), Positives = 97/291 (33%), Gaps = 35/291 (12%)

Query: 111  APPGPPSPSAAD---------TPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQ 161
            +P G P+P AA          TP+ +    P A T  +P  G A P  + +    AA+  
Sbjct: 935  SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP 994

Query: 162  SRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGT----GGAGGDVAGPAGATAIPGA 217
            S        S    P GA P    V  P+     A T    G +    A P      P A
Sbjct: 995  SPKGGPATPS----PKGA-PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAA 1049

Query: 218  RKVPLRARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTE 277
              +P  A   P +  T PS  G    GP+ P +      KGA          P  G  T 
Sbjct: 1050 TPLPKGAPTTPAA--TLPSPKG----GPATPSL------KGAPTPPAATPPSPKGGPATP 1097

Query: 278  AAVLLAAEPLDVFPAGASVLRGPPE--LEPGLFEPPPAVVGNLLYPEPWSVPGCSPTKKS 335
            +       P    P+    L  PP           PP+  G L  P P   P  +P    
Sbjct: 1098 SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAP-TTPAATP 1156

Query: 336  PLTAPRGGLTLNEPLSPLYPAAADSPGGEDGRGHLASFAPFFPDCALPPPP 386
            P  +P+GGL    P       AA  P  + G    +         A PP P
Sbjct: 1157 P--SPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1205



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 83/308 (26%), Positives = 102/308 (33%), Gaps = 54/308 (17%)

Query: 109  GAAPPGP---PSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREAS--------QAAAA 157
            G A P P   P+ S   +  K+  A P+   + A    K AP   A+         A  +
Sbjct: 899  GPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPS 958

Query: 158  ASLQSRSLAALFDSLRHVPGGAEPAGG---EVAAPAAGLGGAGTGGAGGDVAGPA----G 210
                    AA   S +  P    P G      A P +  GG  T    G    PA     
Sbjct: 959  PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS 1018

Query: 211  ATAIPGARKVPLRARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGP 270
                P A   P +  + PP+  T PS  G     P         L KGA       L  P
Sbjct: 1019 PKGSPAATPFP-KGASTPPA-ATPPSPKGSPAATP---------LPKGAPTTPAATLPSP 1067

Query: 271  DYGAGTEAAVLLAAEPLDVFPAGASVLRGPPELEPGLFEPPPAVVGNLLYPEPWSVPGCS 330
              G  T +   L   P        S   GP    P     PPA       P P       
Sbjct: 1068 KGGPATPS---LKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP----PSPKGGLATP 1120

Query: 331  PTKKSPLT------APRGGLTLNEPL-SPLYPAAA-DSPGGEDGRGHLAS----FAPFFP 378
            P K +P T      +P+GGL    P  +P  PAA   SP     +G LA+     AP  P
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP-----KGGLATPPPKGAPTTP 1175

Query: 379  DCALPPPP 386
              A PP P
Sbjct: 1176 -AATPPSP 1182



 Score = 36.2 bits (82), Expect = 0.058
 Identities = 71/309 (22%), Positives = 106/309 (34%), Gaps = 31/309 (10%)

Query: 113  PGPPSPSAADTPAKRPLAAPSAPTVAAP--AHGKAAPRREASQAAAAASLQSRSLAALFD 170
            P P  P A   P  + +   S  +  AP  +  K  P  ++  +A A+S    +L  L D
Sbjct: 735  PSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASS--KGTLTYLAD 792

Query: 171  SLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAG---ATAIP-------GARKV 220
            S   +     P   +   P    G AG     G+++ P     A+ +P       G++  
Sbjct: 793  SPSPLGVSVSP---QTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDS 849

Query: 221  PLRARN-LPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEF--FELLGPDYGAGTE 277
            P    +  PPS    P+ +      P G  V+L   E    +V    F   GP   A  +
Sbjct: 850  PATTHSPTPPSPKGAPTPSAVTPLSPKG--VTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907

Query: 278  AAVL--LAAEPLDV----FPAGASVLRGPPELEPGLFEPPPAVVGNLLYPEPWSVPGCSP 331
            A  L   ++ P        P G      P          PP+  G    P P   P  +P
Sbjct: 908  APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP--TP 965

Query: 332  TKKSPLTAPRGGLTLNEPLSPLYPAAADSPGGEDGRGHLASFAPFFPDCALPPPPPPHQV 391
               +P  +P+GG     P     P AA  P  + G    +      P    PP P     
Sbjct: 966  PAATP-PSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024

Query: 392  SYDYSAGYS 400
            +  +  G S
Sbjct: 1025 ATPFPKGAS 1033



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 59/245 (24%), Positives = 81/245 (33%), Gaps = 55/245 (22%)

Query: 112  PPGPPSPSAADTPAKR-------PLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRS 164
            P G P+P AA  P+ +       P  AP+ P V  P+  K  P   A+  ++     + S
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPS-PKGTPTLPATTPSSKGGPTTPS 1364

Query: 165  LAALFDSLRHVPGGAEPA--GGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPL 222
                       P  A P+  GG    P +   G       GD   PA          +PL
Sbjct: 1365 -----SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA---------VIPL 1410

Query: 223  RARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLL 282
              +  P +  T    A       + P V+   L+K            P  G  T ++   
Sbjct: 1411 SPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT------SAPKGGPATPSS--- 1461

Query: 283  AAEPLDVFPAGASVLRGPPELEPGLFEPPPAVVGNLLYPEPWSVPGCSPTKKSPLT-APR 341
                           +G P L P +  P P        P P  V   S  KK+P T AP 
Sbjct: 1462 ---------------KGDPTL-PAVTPPSPKEP-----PAPKQVATSSSPKKAPATPAPM 1500

Query: 342  GGLTL 346
            G  TL
Sbjct: 1501 GAPTL 1505



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 70/285 (24%), Positives = 95/285 (33%), Gaps = 58/285 (20%)

Query: 112  PPG--PPSPSA-----ADTPAKR--------------PLAAPS-----APTVAAPAHGKA 145
            PP   PPSP       A TP+ +              P A PS     A T  +P  G A
Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPA 1394

Query: 146  APRREASQAAAAASLQSRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDV 205
             P  +    + A    S   A      R   G A P+ G++  PA          A    
Sbjct: 1395 IPSPKGDPTSPAVIPLSPKKAPATPVTRE--GAATPSKGDLTPPAVTPVSLKKAPA---T 1449

Query: 206  AGPAGATAIPGARKVPLRARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFF 265
            + P G  A P ++  P      PPS   EP         P+   V+     K A A    
Sbjct: 1450 SAPKGGPATPSSKGDPTLPAVTPPS-PKEP---------PAPKQVATSSSPKKAPATP-- 1497

Query: 266  ELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGP--------PELEPGLFEPPPAVV-G 316
                   GA T  AV + + P +V PA  S  R P         +  P    P  A++  
Sbjct: 1498 ----APMGAPTLPAV-IPSSPKEV-PATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551

Query: 317  NLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADSP 361
             +  P P   P     K++P T      +    ++P     A SP
Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSP 1596



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 66/274 (24%), Positives = 89/274 (32%), Gaps = 40/274 (14%)

Query: 113  PGPPSPSAADT-PAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALFDS 171
            P  PSP    T PA  PL+   AP       G A P +      A   +          S
Sbjct: 1393 PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPV----------S 1442

Query: 172  LRHVPGGAEPAG--------GEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLR 223
            L+  P  + P G        G+   PA          A   VA  +     P A   P+ 
Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAP-ATPAPMG 1501

Query: 224  ARNLP---PSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAV 280
            A  LP   PS   E          P  P  +L   +  A       L+ P     +    
Sbjct: 1502 APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT 1561

Query: 281  LLAAEPLDVFPA--GASVLRGPPELEPGLFEP---------PPAVV--GNLLYPEPWSVP 327
                 P +  PA   +     PP + P  ++          PPAV        P P +V 
Sbjct: 1562 PAIPTPKEA-PATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620

Query: 328  GCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADSP 361
              SP K     AP+G  T + P++P   +  DSP
Sbjct: 1621 PPSPEKGPATPAPKGTPT-SPPVTP--SSLKDSP 1651


>gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]
          Length = 1006

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 95/369 (25%), Positives = 123/369 (33%), Gaps = 85/369 (23%)

Query: 42  ETGAPAGALLSGAEGGDVREATRDLLSFIDSASSNIKLALDKP-----GKSKRKVNHRKY 96
           E GA   A      GG   E ++   S +D A  +    L +       + +    H++Y
Sbjct: 645 EEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRY 704

Query: 97  LQKQIKRCSGLMGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAA 156
                        AAPPGPP P           AAP AP+ AAP   +   RR+  +  A
Sbjct: 705 YCASRHDPPPRRPAAPPGPPGP-----------AAPPAPSPAAPV--RTRRRRKLYELHA 751

Query: 157 AASLQSRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPG 216
           A +                     P  G   AP +   G+G+G      +GP  A A   
Sbjct: 752 AGA------------------PPPPPPGHAPAPESPRPGSGSG------SGPGLAPA--- 784

Query: 217 ARKVPLRARNLPPSFFTEPSRAGGGGCGPSGPD--------VSLGDLEKGAEAVEFFELL 268
             + P  A + P     +P R   G   P+  D        VS   LE      ++    
Sbjct: 785 --RSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPA 842

Query: 269 GPDYGA-GTEAAVLLAAEP--------LDVFPAGASVLRGPPELEPGLFEPPPAVVGNLL 319
            P  GA G  AA      P        L+ F     +L G P   PG+    PA  G   
Sbjct: 843 APPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRG--- 899

Query: 320 YPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADSPGGEDGRGHLASFAPFFPD 379
            P P   P  SP   S    PR GL   EP  P  P    SP                P+
Sbjct: 900 -PSPAPAPAASPQPGS--RGPRDGLG-PEPQEP-PPGPPPSPAAA-------------PE 941

Query: 380 CALPPPPPP 388
              PPP PP
Sbjct: 942 AVPPPPAPP 950



 Score = 28.9 bits (63), Expect = 9.3
 Identities = 32/116 (27%), Positives = 43/116 (37%), Gaps = 22/116 (18%)

Query: 107 LMGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLA 166
           ++G   PGP +PS   +P + P  A     +++P  G +    E   A            
Sbjct: 475 ILGPGEPGPQAPSRTPSP-RSPAPARVKAELSSPTPGSSPVPGELGLA-----------G 522

Query: 167 ALFDSLRHVPGGAEPAGGEVAAPAAGL--------GGAGTGGA--GGDVAGPAGAT 212
           ALF         A P   E+ A  + L         GAG GGA  G     P GAT
Sbjct: 523 ALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGAT 578


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 56/195 (28%), Positives = 74/195 (37%), Gaps = 30/195 (15%)

Query: 124 PAKRPLAAPSAPTVAAPAH------GKAAPRREASQAAAAASLQSRSLAALFDSLRHVPG 177
           P   P ++PS      PA+      G   PR E  Q    A ++   L      +   PG
Sbjct: 419 PYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGML------IEGPPG 472

Query: 178 GAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRARNLPPSFFTEPSR 237
              PAG  +  P   +G  G  G  G+  GP G   +PGA  +P      P +    P R
Sbjct: 473 PEGPAG--LPGPPGTMGPTGQVGDPGE-RGPPGRPGLPGADGLP----GPPGTMLMLPFR 525

Query: 238 AGGGG-CGPSGPDVSLGDLEKGAEAVEF----------FELLGPDYGAGTEAAVLLAAEP 286
            GGGG  G  GP VS  + +  A   +             L G     G   +  L  EP
Sbjct: 526 FGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEP 585

Query: 287 LDVFPAGASVLRGPP 301
            DV P G   ++GPP
Sbjct: 586 GDVGPQGPRGVQGPP 600



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 94/365 (25%), Positives = 115/365 (31%), Gaps = 61/365 (16%)

Query: 106  GLMG-AAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRS 164
            GL G   PPGPP P  A +P +R  A  + P       G   P   A +  A      + 
Sbjct: 1072 GLKGNEGPPGPPGP--AGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQG 1129

Query: 165  LAALFDSLR---HVPGGAEPAG--------GEVAAPA--AGLGGAGTGGAGGDVA----- 206
             A   D L+    +PG A P G        GE+  P      G  G  G  G        
Sbjct: 1130 PAGR-DGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPI 1188

Query: 207  ---GPAGATAIPGAR--------------------KVPLRARNLPPSFFTEPSRAGGGGC 243
               GP+GA   PG R                      P+  + LP     +      G  
Sbjct: 1189 GQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQM 1248

Query: 244  GPSGPDVSLGDL-EKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGPPE 302
            GP GP    G     GA+  +     GP  G G   AV    EP +    G     GPP 
Sbjct: 1249 GPPGPPGPRGPSGAPGADGPQ-----GPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPG 1303

Query: 303  LEPGLFEP----PPAVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAA 358
             +    E     P    G    P P   PG    K SP   P G      P     PA  
Sbjct: 1304 PKGERGEKGESGPSGAAGP---PGPKGPPGDDGPKGSP--GPVGFPGDPGPPGEPGPAGQ 1358

Query: 359  DSPGGEDG-RGHLASFAPFFPDCALPPPPPPHQVSYDYSAGYSRTAYSSLWRSDGVWEGA 417
            D P G+ G  G         P     P  PP +      AG          + +   EG 
Sbjct: 1359 DGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGP 1418

Query: 418  PGEEG 422
            PG+ G
Sbjct: 1419 PGKTG 1423



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 93/377 (24%), Positives = 116/377 (30%), Gaps = 89/377 (23%)

Query: 106 GLMGAAPPGPPSPSAAD------------------TPAKRP-------LAAPSAPTVAAP 140
           G++   PPGP  P+                      P  RP       L  P    +  P
Sbjct: 464 GMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLP 523

Query: 141 AH-------GKAAPRREASQAAAAASLQSRSLAALFDSLRHVPGGAEPAG-----GEVAA 188
                    G   P   A ++ A A LQ   LA        + G A P G     G V  
Sbjct: 524 FRFGGGGDAGSKGPMVSAQESQAQAILQQARLA--------LRGPAGPMGLTGRPGPVGP 575

Query: 189 PAAGLGGAGTGGAGGDVA--GPAGATAIPGARKVPLR--------ARNLPPSFFTEPSRA 238
           P +G    G  G  GDV   GP G    PG    P R        AR +P     +  R 
Sbjct: 576 PGSG----GLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRG 631

Query: 239 GGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLR 298
             G  G  G     GD              G D   G +  V     P +  P G    +
Sbjct: 632 FDGLAGLPGEKGHRGDPGPSGPPGP----PGDDGERGDDGEVGPRGLPGEPGPRGLLGPK 687

Query: 299 GPPELEPGLFEPPPAVVGNLLYP------EPWSVPGCSPTKKSP----LTAPRGGLTLNE 348
           GPP   PG    PP V G    P       P   PG    + +P    L  P+G +    
Sbjct: 688 GPPG-PPG----PPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPG 742

Query: 349 PLSPL-YPAAADSPGGEDGRGHLASFAPFFPDCALPPPPPPHQVSYDYSAGYSRTAYSSL 407
              PL  P     PG +   GH     P        PP P   + Y    G         
Sbjct: 743 EKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVK------- 795

Query: 408 WRSDGV--WEGAPGEEG 422
             +DG+   +G  GE+G
Sbjct: 796 -GADGIRGLKGTKGEKG 811



 Score = 37.4 bits (85), Expect = 0.026
 Identities = 70/237 (29%), Positives = 78/237 (32%), Gaps = 41/237 (17%)

Query: 105  SGLMGAA-PPGPPSPSAADTPAKRP-----LAAPSAPTVAAPAHGKAAPRREASQAAAAA 158
            SG  GAA PPGP  P   D P   P        P  P    PA     P  +        
Sbjct: 1314 SGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQ 1373

Query: 159  SLQSRSLAALFDS----LRHVPGGAEPAG--GEVAA--------PAAGLGGAGTGGAGGD 204
            +           S     R  PG A P G  GE  A        P    G  G  GA G 
Sbjct: 1374 TGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGK 1433

Query: 205  VAGPAGATAIPGARKVPLRARNLPPSFFTEPSRAG-GGGCGPSGPDVSLGDL----EKGA 259
              GP G   IPG    P+  + LP S    P   G  G  GP G     GD     EKG 
Sbjct: 1434 -PGPDGLRGIPG----PVGEQGLPGS----PGPDGPPGPMGPPGLPGLKGDSGPKGEKGH 1484

Query: 260  EAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGP-----PELEPGLFEPP 311
              +    L+GP    G +    L        P G   + GP     P   PGL  PP
Sbjct: 1485 PGL--IGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPP 1539



 Score = 36.2 bits (82), Expect = 0.058
 Identities = 95/401 (23%), Positives = 124/401 (30%), Gaps = 68/401 (16%)

Query: 12  PFVPFGFGGSPDGLGGAFGALDKGCCFEDDETGAPAGALLSGAEGGDVREATRDLLSFID 71
           P  P G  G P  +G      D G      E G P    L GA+G      T  +L F  
Sbjct: 473 PEGPAGLPGPPGTMGPTGQVGDPG------ERGPPGRPGLPGADGLPGPPGTMLMLPFRF 526

Query: 72  SASSNIKLALDKPGKSKRKVNHRKYLQKQ---IKRCSGLMG-AAPPGPPSPSAADTPAKR 127
               +       P  S ++   +  LQ+    ++  +G MG    PGP  P  +      
Sbjct: 527 GGGGDA--GSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGE 584

Query: 128 PLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALFDSLRHVPGGAEPAGGEVA 187
           P      P       G   P  +  +   A S          D  R +PG   P G    
Sbjct: 585 P--GDVGPQGPRGVQGPPGPAGKPGRRGRAGS----------DGARGMPGQTGPKGDRGF 632

Query: 188 APAAGL----------GGAGTGGAGGD--------VAGPAGATAIPGARKVPLRARNLPP 229
              AGL          G +G  G  GD          GP G    PG R   L     PP
Sbjct: 633 DGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPR--GLLGPKGPP 690

Query: 230 SFFTEPSRAG-------GGGCGPSGPDVSLGDL-EKGAEAVEFFE-LLGPDYGAGTEAAV 280
                P   G        G  GP G     G     GA+ +   +  +GP    G     
Sbjct: 691 GPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKP 750

Query: 281 LLAAEPLDVFPAGASVLRGPPELEPGLFEPPPAVVGNLLYPEPWSVPGCSPTK------- 333
            L   P    P G     GPP  + G  + PP   G + YP P  V G    +       
Sbjct: 751 GLPGMPGADGPPGHPGKEGPPGEKGG--QGPPGPQGPIGYPGPRGVKGADGIRGLKGTKG 808

Query: 334 ---KSPLTAPRGGLTL---NEPLSPLYPAAADSPGGEDGRG 368
              +      +G + +      + P  P   D P G  GRG
Sbjct: 809 EKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRG 849


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 113/431 (26%), Positives = 140/431 (32%), Gaps = 69/431 (16%)

Query: 10   THPFVPFGFGGSPDGLGGAFGALDKGCCFEDDETGAPAGALLSGAEGGDVREATRDLLSF 69
            T P  P GF G+P   G   G  ++G   E  E G P  A   G  G       + +   
Sbjct: 803  TGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKG- 861

Query: 70   IDSASSNIKLALDKPGKSKRKVNHRKYLQKQIKRCSGLMGA----APPGPPSPSAADTPA 125
             +  S     A   PG                    GL G       PGPP PS +  P 
Sbjct: 862  -ERGSPGGPGAAGFPG------------------ARGLPGPPGSNGNPGPPGPSGS--PG 900

Query: 126  KRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALFDSLRHVPGGAEPAGGE 185
            K     P+  T A  + G + P+ +A Q     S  ++            PG   P G  
Sbjct: 901  KDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQG----------PPGAPGPLGIA 950

Query: 186  VAAPAAGLGGA----------GTGGAGGDVAGPAGATAIPGARKVPLRARNLPPSFFT-- 233
                A GL G           G  G  G+ +G  GA  + G R  P   + LP    T  
Sbjct: 951  GITGARGLAGPPGMPGPRGSPGPQGVKGE-SGKPGANGLSGERGPP-GPQGLPGLAGTAG 1008

Query: 234  EPSRAGGGGC-GPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPA 292
            EP R G  G  G  G D S G   KG          G +   G   A      P  V PA
Sbjct: 1009 EPGRDGNPGSDGLPGRDGSPGG--KGDR--------GENGSPGAPGAPGHPGPPGPVGPA 1058

Query: 293  GASVLRGPPELEPGLFEPPPAVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLS- 351
            G S  RG  E  P      P   G+   P P       P      T  RG   +      
Sbjct: 1059 GKSGDRG--ESGPAGPAGAPGPAGSRGAPGPQG-----PRGDKGETGERGAAGIKGHRGF 1111

Query: 352  PLYPAAADSPGGEDGRGHLASFAPFFPDCALPPPPPPHQVSYDYSAGYSRTAYSSLWRSD 411
            P  P A  SPG    +G + S  P  P   + P  PP +       G          R +
Sbjct: 1112 PGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGE 1171

Query: 412  GVWEGAPGEEG 422
               EG+PG  G
Sbjct: 1172 RGSEGSPGHPG 1182



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 104/362 (28%), Positives = 115/362 (31%), Gaps = 81/362 (22%)

Query: 112  PPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALFDS 171
            P GPP P A     K    AP  P +A P  G    R E      A              
Sbjct: 766  PIGPPGP-AGQPGDKGEGGAPGLPGIAGP-RGSPGERGETGPPGPAG------------- 810

Query: 172  LRHVPG-GAEPAG-GEVAAPAA-GLGG----AGTGGAGGDVAGPAGATAIPGARKVP--- 221
                PG   EP G GE  AP   G GG    AG  G  G  AGP G   + G R  P   
Sbjct: 811  FPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGP-AGPPGPQGVKGERGSPGGP 869

Query: 222  -----LRARNL--PPSFFTEPSRAGGGGC----GPSGPDVSLGDLEKGAEAVEFFELLGP 270
                   AR L  PP     P   G  G     GP GP  + G    G+  V      GP
Sbjct: 870  GAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTG--APGSPGVS-----GP 922

Query: 271  DYGAGTEA--------AVLLAAEPLDVFP-AGASVLRGPPELEPGLFEPPPAVV------ 315
               AG               A  PL +    GA  L GPP +      P P  V      
Sbjct: 923  KGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGK 982

Query: 316  -------GNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADSPGGEDGRG 368
                   G    P P  +PG + T   P    R G     P S   P    SPGG+  RG
Sbjct: 983  PGANGLSGERGPPGPQGLPGLAGTAGEP---GRDG----NPGSDGLPGRDGSPGGKGDRG 1035

Query: 369  HLAS----FAPFFPDCALPPPPPPHQVSYDYSAGYSRTAYSSLWRSDGVWEGAPGEEGAH 424
               S     AP  P     PP P          G S  A  +         GAPG +G  
Sbjct: 1036 ENGSPGAPGAPGHPG----PPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPR 1091

Query: 425  RD 426
             D
Sbjct: 1092 GD 1093



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 80/274 (29%), Positives = 98/274 (35%), Gaps = 64/274 (23%)

Query: 106 GLMGAAPPGPPSPSAAD-TPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRS 164
           GLMGA   GPP P+ A+  P  R  A          A G+  PR E  +A          
Sbjct: 408 GLMGAR--GPPGPAGANGAPGLRGGAGEPGKN---GAKGEPGPRGERGEAGIPG------ 456

Query: 165 LAALFDSLRHVPG--GAEPAGGEVAAPAA-GL-GGAGTGGAGGDVAGPAGATAIPGARKV 220
                     VPG  G +   G    P A GL G AG  GA G   GPAG   IPG  K 
Sbjct: 457 ----------VPGAKGEDGKDGSPGEPGANGLPGAAGERGAPG-FRGPAGPNGIPG-EKG 504

Query: 221 PLRARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVE----FFELLGPDYGAGT 276
           P   R  P               GP+GP  + G  E G + V        + G   G G+
Sbjct: 505 PAGERGAP---------------GPAGPRGAAG--EPGRDGVPGGPGMRGMPGSPGGPGS 547

Query: 277 EAAVLLAAEPLDVFPAGASVLRGPPELEPGLFEPPPAVVGNLLYPEPW---SVPGCSPTK 333
           +       +P      G S   GPP   P      P V+G   +P P      PG +  +
Sbjct: 548 D------GKPGPPGSQGESGRPGPP--GPSGPRGQPGVMG---FPGPKGNDGAPGKNGER 596

Query: 334 KSP-LTAPRGGLTLNEPLSPLYPAAADSPGGEDG 366
             P    P+G    N    P  P     PGG+ G
Sbjct: 597 GGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKG 630



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 81/311 (26%), Positives = 99/311 (31%), Gaps = 73/311 (23%)

Query: 110 AAPPGPP-------------SPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAA 156
           A PPGPP             SP     P +   A PS P     A G + P  +  ++  
Sbjct: 176 AGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGR 235

Query: 157 AASLQSRSLAALFDSLRHVPGGAEPAG--------------------GEVAAPAAGLGGA 196
                 R L          PG   PAG                    GE  AP  GL G 
Sbjct: 236 PGRPGERGLPG-------PPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAP--GLKGE 286

Query: 197 -GTGGAGGDVAGPAGATAIPGARKVPLRARNLPPSF---FTEPSRAGGGGCGPSGPDVSL 252
            G  G  G   GP G    PG R  P     LP +      + +R   G  GP GP  + 
Sbjct: 287 NGLPGENG-APGPMGPRGAPGERGRP----GLPGAAGARGNDGARGSDGQPGPPGPPGTA 341

Query: 253 G-DLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGPP---------- 301
           G     GA+       +GP    G+  A     EP     AGA    GPP          
Sbjct: 342 GFPGSPGAKGE-----VGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKG 396

Query: 302 ELEPGLFEPPPAVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADSP 361
           E+ P      P ++G    P P    G +P  +     P       EP        A  P
Sbjct: 397 EMGPAGIPGAPGLMGARGPPGPAGANG-APGLRGGAGEPGKNGAKGEPGPRGERGEAGIP 455

Query: 362 G-----GEDGR 367
           G     GEDG+
Sbjct: 456 GVPGAKGEDGK 466



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 75/275 (27%), Positives = 83/275 (30%), Gaps = 59/275 (21%)

Query: 112 PPGPPSPSA--ADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALF 169
           PPGP  P     DT    P      P    P      P     +  A A           
Sbjct: 619 PPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAP---------- 668

Query: 170 DSLRHVPGGAEPAG--GEVAAP----AAGL-GGAGTGGAGGDVA-----GPAGATAIPGA 217
                 PGG   AG  GE   P    A GL GGAG  G  G        GP GA   PG 
Sbjct: 669 ----GAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGL 724

Query: 218 RKVPLRARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTE 277
           + +P               R G G  GP G     G    GA+ V   +  GP    G  
Sbjct: 725 QGMP-------------GERGGLGSPGPKGDKGEPGG--PGADGVPGKD--GPRGPTGPI 767

Query: 278 AAVLLAAEPLDVFPAGASVLRG--PPELEPGL--FEPPPAVVGNLLYPEPWSVPGCSPTK 333
                A +P D    GA  L G   P   PG      PP   G    P     PG    +
Sbjct: 768 GPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGER 827

Query: 334 KSPLTAPRGGLTLNEPLSPLYPAAADSPGGEDGRG 368
            +P     GG           P  A  PGG    G
Sbjct: 828 GAPGEKGEGG----------PPGVAGPPGGSGPAG 852



 Score = 36.2 bits (82), Expect = 0.058
 Identities = 72/289 (24%), Positives = 92/289 (31%), Gaps = 36/289 (12%)

Query: 109 GAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAH----GKAAPRREASQ--AAAAASLQS 162
           GA PPGP     A  P   P AA +      P      G   P+ +  +     A  +  
Sbjct: 697 GAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPG 756

Query: 163 RSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGG-AGTGGAGGD-----VAGPAGATAIPG 216
           +            PG A   G +    A GL G AG  G+ G+       GPAG    PG
Sbjct: 757 KDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPG 816

Query: 217 ARKVP----------LRARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDL-EKGAEAVEFF 265
               P           +    PP     P   G G  GP GP    G+    G      F
Sbjct: 817 QNGEPGGKGERGAPGEKGEGGPPGVAGPP--GGSGPAGPPGPQGVKGERGSPGGPGAAGF 874

Query: 266 E----LLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGPPELEPGLFEPPPAVVGNLLYP 321
                L GP    G       +  P    P G +   G P   PG+  P     G+   P
Sbjct: 875 PGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPG-SPGVSGPK----GDAGQP 929

Query: 322 EPWSVPGCSPTKKSPLTAPRGGLTLNEPLS--PLYPAAADSPGGEDGRG 368
                PG      +P      G+T    L+  P  P    SPG +  +G
Sbjct: 930 GEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKG 978


>gi|84570137 homeobox B3 [Homo sapiens]
          Length = 431

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 36/116 (31%), Positives = 48/116 (41%), Gaps = 7/116 (6%)

Query: 110 AAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALF 169
           +APPG P PSAA T A    +    P+ + P           ++       +SR  + L 
Sbjct: 84  SAPPGSPPPSAAPTSATSNSSNGGGPSKSGPPKCGPGTNSTLTKQIFPWMKESRQTSKLK 143

Query: 170 DSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRAR 225
           ++    PG AE  GG       G GG G+GG+GG   G  G    P       RAR
Sbjct: 144 NNS---PGTAEGCGGG----GGGGGGGGSGGSGGGGGGGGGGDKSPPGSAASKRAR 192


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 83/321 (25%), Positives = 109/321 (33%), Gaps = 68/321 (21%)

Query: 107 LMGAAPPGPP-SPSAADTPAKRP--LAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSR 163
           L G  P  P  S   A  P  +P  L  PS P + +       P    S +  + +L   
Sbjct: 376 LEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNL--- 432

Query: 164 SLAALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLR 223
                  S  H+P     + G    P   +  +  G   G ++   GA A P A K P+ 
Sbjct: 433 -----LGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPV- 486

Query: 224 ARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYG---AGTEAAV 280
              +P      PS   G G GP+ P   L     G EA   F    P+ G   +G     
Sbjct: 487 ---VPSPVLQSPSEGLGMGAGPACPLPPLA----GGEA---FPFPSPEQGLALSGAGFPG 536

Query: 281 LLAAEPLDVF---PAGASVLR------------------------GP-PELEPGLFEPPP 312
           +L A PL +    P  + +L                         GP P L PG  E P 
Sbjct: 537 MLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPS 596

Query: 313 AVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADSPGGEDGRG---- 368
            +V +LL P P      S     P   P   L    PL  L P A D  G  +G G    
Sbjct: 597 LLVASLLPPPP------SDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSG 650

Query: 369 ----HLASFAP-FFPDCALPP 384
                L   +P  FP  + PP
Sbjct: 651 EPFSGLGDLSPLLFPPLSAPP 671


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 57/228 (25%), Positives = 82/228 (35%), Gaps = 15/228 (6%)

Query: 126 KRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALFDSLRHVPGGAEPAGGE 185
           ++P +  S PT   P   +A  + +AS AAA ASL   S AA   +   +P G  P    
Sbjct: 426 RQPKSPGSTPTT--PTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFS 483

Query: 186 VAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRARNLPPSFFTEPSRAGGGGCGP 245
             + +       TG      +G   + A PG    P     +PPS  +           P
Sbjct: 484 FGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPG--PSTFSFVPPSKASLAPTPAASPVAP 541

Query: 246 SGPDVSLGD--LEKGAEAVEFFEL------LGPDYGAGTEAAVLLAAEPLDVFPAGASVL 297
           S    S G    +   E+     +      + P +   T A  +  +E          V 
Sbjct: 542 SAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPVS 601

Query: 298 --RGPPELEPGLFEPPPAVVGNLLYPEPWSVPGCS-PTKKSPLTAPRG 342
             +  P + P      PA  G L +P P S P  S P K S L +P G
Sbjct: 602 SSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPSG 649



 Score = 30.0 bits (66), Expect = 4.2
 Identities = 61/265 (23%), Positives = 91/265 (34%), Gaps = 49/265 (18%)

Query: 112  PPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRRE-ASQAAAAASLQSRSLAALFD 170
            P G  S   A    K    +PS P  A  A   AA RR+ ASQA A  +L          
Sbjct: 1062 PQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVNTLTE-------S 1114

Query: 171  SLRHVPG--GAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRARNLP 228
            +L++VP     +      A P+  +G           + P      P     P+ A    
Sbjct: 1115 TLKNVPQVVNVQELKNNPATPSTAMGS----------SVPYSTAKTPHPVLTPVAANQAK 1164

Query: 229  PSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLD 288
                    +       PSGP  + G L  G +A    ++        T +A    ++P  
Sbjct: 1165 QGSLINSLK-------PSGPTPASGQLSSGDKASGTAKI--ETAVTSTPSASGQFSKPFS 1215

Query: 289  VFPAGASVLRGPPELEPGLFEPPP-----AVVGNLLYPEPWSVP-------GCSPTKKS- 335
              P+G            G+  P P     A  G     +  S P       G  P+ ++ 
Sbjct: 1216 FSPSGTG-------FNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAI 1268

Query: 336  PLTAPRGGLTLNEPLSPLYPAAADS 360
            P ++P  G+T     +P  PAA+ S
Sbjct: 1269 PESSPPSGITSASNTTPGEPAASSS 1293



 Score = 30.0 bits (66), Expect = 4.2
 Identities = 48/193 (24%), Positives = 58/193 (30%), Gaps = 26/193 (13%)

Query: 110  AAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALF 169
            A PP   S SA +        APSA  V        AP     Q  + AS  + +     
Sbjct: 1646 AQPPAASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQV-- 1703

Query: 170  DSLRHVPGGAEPAGGEVAAPAAG---LGGAGTGGAGGDVAGPAGATAIPGARKVPL---R 223
                   G + PA G  A    G    G A   G     A    + + PG   VP     
Sbjct: 1704 ----SSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQP 1759

Query: 224  ARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYG---------- 273
            A + P S  T  S  G      S    S G          F +   P +G          
Sbjct: 1760 ASSTPTS--TSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGS 1817

Query: 274  --AGTEAAVLLAA 284
               GT AA   AA
Sbjct: 1818 VFGGTSAATTTAA 1830


>gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]
          Length = 796

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 65/248 (26%), Positives = 86/248 (34%), Gaps = 11/248 (4%)

Query: 99  KQIKRCSG-LMGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAA 157
           +Q+KR  G       PGPP P    T A     A +A   AA A   AA +++  Q    
Sbjct: 55  RQLKRAHGCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAA-AAAAQQQQQQQQQQQ 113

Query: 158 ASLQSRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGA 217
              Q +        L HV G ++PA   V A  +GL   G   A    A  A A      
Sbjct: 114 QQQQQQQQQQQQQQLNHVDGSSKPA---VLAAPSGLERYGLSAAAAAAAAAAAAVEQRSR 170

Query: 218 RKVPLRARNLPPSFFTEPSRAGGGGCGPSG---PDVSLGDLEKGAEAVEFFELLGPDYGA 274
            + P    +L  S  T  +R   G  GP+G   P    G  E   ++             
Sbjct: 171 FEYPPPPVSLGSSSHT--ARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASR 228

Query: 275 GTEAAVLLAAEPLDVFPAGASVLRGPPELEPGLFEPPPAVVGNLLYPEPWSVPGCSPTKK 334
                 L+   P +    G   L  PP L P      PA    L  P P ++    P   
Sbjct: 229 RGTHGGLVTGLP-NPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPPTP 287

Query: 335 SPLTAPRG 342
           +P  AP G
Sbjct: 288 APPGAPGG 295


>gi|157426823 NK2 homeobox 4 [Homo sapiens]
          Length = 354

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 62/189 (32%), Positives = 77/189 (40%), Gaps = 27/189 (14%)

Query: 97  LQKQIKRCSGLMGAAPPGPPSPSAADTPAKRPLAAPS--APTVAA--PAHGKAAPRREAS 152
           +++  K+ SG M  APPG  +P  A    + P   PS  A TVA   P+H  A     A+
Sbjct: 20  IEETYKKFSGAMDGAPPGLGAPLGAAAAYRAPPPGPSSQAATVAGMQPSHAMAGHNAAAA 79

Query: 153 QAAAAASLQSRSLAALFDSLRHVPGGAE--PAGGEVAAPAAGLGGAGTGGAGGDVAGPAG 210
            AAAAA       AA   +  H+P G    P G   +    GLG  G   A  D      
Sbjct: 80  AAAAAA-------AAAAAATYHMPPGVSQFPHGAMGSYCNGGLGNMGELPAYTDGMRGGA 132

Query: 211 ATAIPGARKVPLRARNLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGP 270
           AT   GA   P   R    S F  PS AG    G       +G L   A+A    + LGP
Sbjct: 133 ATGWYGANPDP---RYSSISRFMGPS-AGVNVAG-------MGSLTGIADAA---KSLGP 178

Query: 271 DYGAGTEAA 279
            + A   AA
Sbjct: 179 LHAAAAAAA 187



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 33/112 (29%), Positives = 43/112 (38%), Gaps = 16/112 (14%)

Query: 92  NHRKYLQKQIK-------RCSGLMGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGK 144
           NHR  +++Q K       +  G +G  PP PPSP     P       P     + P  G+
Sbjct: 239 NHRYKMKRQAKDKAAQQLQQEGGLGPPPPPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQ 298

Query: 145 AAPRREASQAAAAASLQSRSLAALFDSLRHVPGGA----EPAGGEVAAPAAG 192
           A P+  A   A      S S  AL     H PGG     + A GE +    G
Sbjct: 299 AGPQPPAPTPAPELEELSPSPPAL-----HGPGGGLAALDAAAGEYSGGVLG 345


>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
          Length = 500

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 60/234 (25%), Positives = 77/234 (32%), Gaps = 20/234 (8%)

Query: 174 HVPGGAEPAGGEVA---APAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRA-RNLPP 229
           ++PG +  A G +    A  AG GG G GG GG  AG  G    PG+  V   A R  P 
Sbjct: 9   YLPGNSLLAAGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPS 68

Query: 230 SFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDV 289
           S     S    G    S     L    +   A+       P   A   AA   A E    
Sbjct: 69  SVKMVQSDFMQGAMAASNGGHMLSHAHQWVTAL-------PHAAAAAAAAAAAAVEASSP 121

Query: 290 FPAGASVLRGPPELEPGLFEPPPAVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEP 349
           +   A  + G P+  P    PPP   G    P+     G            RG   L  P
Sbjct: 122 WSGSAVGMAGSPQQPPQ--PPPPPPQG----PDVKGGAGRDDLHAGTALHHRGPPHLGPP 175

Query: 350 LSPL---YPAAADSPGGEDGRGHLASFAPFFPDCALPPPPPPHQVSYDYSAGYS 400
             P    +P    +          A+ A   P  A    PPP  + Y    G++
Sbjct: 176 PPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFT 229



 Score = 32.3 bits (72), Expect = 0.84
 Identities = 28/94 (29%), Positives = 30/94 (31%), Gaps = 11/94 (11%)

Query: 115 PPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALFDSLRH 174
           PP P     P     AA +A   AA A     P     Q     SL           L  
Sbjct: 175 PPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSL-----------LYS 223

Query: 175 VPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGP 208
            PGG    G   A P  G GG G GG    +  P
Sbjct: 224 QPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHP 257



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 40/141 (28%), Positives = 52/141 (36%), Gaps = 25/141 (17%)

Query: 132 PSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALFD----SLRHVPGGAEPAGGEVA 187
           P  P    P    AA    A+ AAAAA+    S+A        SL +   G     G ++
Sbjct: 176 PPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLS 235

Query: 188 APAAGLGGAGTGGAGGDVAGPAGATAIPGARK--VPLRARN------------LPPSFFT 233
           AP       G GG GG   G A +   PG  +   P  A +              P    
Sbjct: 236 APP------GPGGGGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHPHHAQ 289

Query: 234 EPSRAGGGGCGPSGPDVSLGD 254
            P   GGGG G +GP ++  D
Sbjct: 290 GPPHHGGGG-GGAGPGLNSHD 309


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 81/340 (23%), Positives = 107/340 (31%), Gaps = 81/340 (23%)

Query: 83  KPGKSKRKVNHRKYLQKQIKRCSGLMGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAH 142
           +PG   +    +  + K+       +G AP  P S  +   PA  PLA  SAP  AAPA+
Sbjct: 296 RPG-DPQSAQDKARMDKEYLSLMAELGEAPV-PASVGSTSGPATTPLA--SAPRPAAPAN 351

Query: 143 GKAAPRREASQAAAAASLQSRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAG 202
               P   ++  +    + S                    G   + P  G+ G G GG G
Sbjct: 352 NPPPPSLMSTTQSRPPWMNS--------------------GPSESRPYHGMHGGGPGGPG 391

Query: 203 GDVAGP-------AGATAIPGARKVPLRARNLPPSFFTEPSRAGGGGCGPSGP------D 249
           G   GP          T   G   +       PP +   P      G  P G       D
Sbjct: 392 G---GPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMD 448

Query: 250 VSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGPPELEPGLFE 309
             LG    G+      +  G           ++   P+ + P        PP    G  +
Sbjct: 449 QYLGSTPVGSGVYRLHQGKG-----------MMPPPPMGMMPP-------PPPPPSG--Q 488

Query: 310 PPPAVVGNL-------LYPEPWSVPGCSPTKKSPL--------TAPRGGLTLNEPLSPLY 354
           PPP   G L         P P   P  S    +PL        T    G     P     
Sbjct: 489 PPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQ 548

Query: 355 PAAADSPGGEDGRGHLA------SFAPFFPDCALPPPPPP 388
            AAA SPG    +G+           P  P  A PPPPPP
Sbjct: 549 AAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPP 588


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 81/340 (23%), Positives = 107/340 (31%), Gaps = 81/340 (23%)

Query: 83  KPGKSKRKVNHRKYLQKQIKRCSGLMGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAH 142
           +PG   +    +  + K+       +G AP  P S  +   PA  PLA  SAP  AAPA+
Sbjct: 296 RPG-DPQSAQDKARMDKEYLSLMAELGEAPV-PASVGSTSGPATTPLA--SAPRPAAPAN 351

Query: 143 GKAAPRREASQAAAAASLQSRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAG 202
               P   ++  +    + S                    G   + P  G+ G G GG G
Sbjct: 352 NPPPPSLMSTTQSRPPWMNS--------------------GPSESRPYHGMHGGGPGGPG 391

Query: 203 GDVAGP-------AGATAIPGARKVPLRARNLPPSFFTEPSRAGGGGCGPSGP------D 249
           G   GP          T   G   +       PP +   P      G  P G       D
Sbjct: 392 G---GPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMD 448

Query: 250 VSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGPPELEPGLFE 309
             LG    G+      +  G           ++   P+ + P        PP    G  +
Sbjct: 449 QYLGSTPVGSGVYRLHQGKG-----------MMPPPPMGMMPP-------PPPPPSG--Q 488

Query: 310 PPPAVVGNL-------LYPEPWSVPGCSPTKKSPL--------TAPRGGLTLNEPLSPLY 354
           PPP   G L         P P   P  S    +PL        T    G     P     
Sbjct: 489 PPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQ 548

Query: 355 PAAADSPGGEDGRGHLA------SFAPFFPDCALPPPPPP 388
            AAA SPG    +G+           P  P  A PPPPPP
Sbjct: 549 AAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPP 588


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 45/145 (31%), Positives = 56/145 (38%), Gaps = 22/145 (15%)

Query: 111 APPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALFD 170
           APP PP+P AA  PA+ P AA +A T A P+ G A P   A +AA  A+      A    
Sbjct: 132 APPPPPAPVAAAAPARAPRAAAAAAT-APPSPGPAQPGPRAQRAAPLAAPPPAPAAP--- 187

Query: 171 SLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRARNLPPS 230
                P  A PAG   A P A             VA        P     P + +  PP 
Sbjct: 188 -----PAVAPPAGPRRAPPPA-------------VAAREPPLPPPPQPPAPPQQQQPPPP 229

Query: 231 FFTEPSRAGGGGCGPSGPDVSLGDL 255
               P   G    G +   VSL ++
Sbjct: 230 QPQPPPEGGAVRAGGAARPVSLREV 254



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 45/127 (35%), Positives = 54/127 (42%), Gaps = 17/127 (13%)

Query: 109 GAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAAL 168
           GA PP PP         + P  AP+A   AAP    A P   A  AAAA +   R+ AA 
Sbjct: 105 GATPPAPP---------RAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAA 155

Query: 169 FDSLRHVPGGAEPA-GGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIP----GARKVPLR 223
             +    PG A+P    + AAP A    A    A   VA PAG    P     AR+ PL 
Sbjct: 156 -ATAPPSPGPAQPGPRAQRAAPLAAPPPA--PAAPPAVAPPAGPRRAPPPAVAAREPPLP 212

Query: 224 ARNLPPS 230
               PP+
Sbjct: 213 PPPQPPA 219


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 83/344 (24%), Positives = 117/344 (34%), Gaps = 62/344 (18%)

Query: 111 APPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRREASQAAAAASLQSRSLAALFD 170
           +P   P P A    A  PL AP +P  + P    A P  +A  A A   LQ+        
Sbjct: 612 SPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA-------- 663

Query: 171 SLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRAR---NL 227
                P  + P     + PA               + P   +A P ++  P  A     +
Sbjct: 664 --PFSPPPSPPVQAPFSPPA---------------SPPVSPSATPPSQAPPSLAAPPLQV 706

Query: 228 PPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPL 287
           PPS    P  +      P  P        +   +      + P          LLAA PL
Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL 766

Query: 288 DVFPAGASVL------RGPPELEPGLFEPP----PAVVGNLLYPEPWS-------VPGCS 330
            V P+  + L      + PP+  P L  PP    P+   +     P+S        P  +
Sbjct: 767 QVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 826

Query: 331 PTKKSP--LTAPRGGLTLNEPLSPLY--PAAADSPGGE---DGRGHLASFAPFFPDCALP 383
           P  ++P  L AP   +  + P SP    P    +PG +    G     + AP       P
Sbjct: 827 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG------P 880

Query: 384 PPPPPHQVSYDYS----AGYSRTAYSSLWRSDGVWEGAPGEEGA 423
           PPPP    S   S    AG+S +A S+     G   G  G   A
Sbjct: 881 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 924



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 92/369 (24%), Positives = 119/369 (32%), Gaps = 102/369 (27%)

Query: 103 RCSGLMGAAPPGPPSPSAADTPA------------KRPLAAPSAPTVAAPAHGKAAPRRE 150
           R  GL+   PPG P P    TPA            ++PL A  A  +      ++APR  
Sbjct: 20  RAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPL-AERAGGIGGATIPESAPRAG 78

Query: 151 ASQAAAAASLQSRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLG---------------- 194
            +++A  +S    S           P     + G V++P    G                
Sbjct: 79  PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138

Query: 195 ---------------GAGTGGAGGDVAGPAGATAIP-------------GARKVPLRARN 226
                           A + GA  D +GP   T  P             G  +    AR 
Sbjct: 139 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 198

Query: 227 LPPS-------------FFTEPS-------RAGGGGCGPSGPDVSLGDLEKGAEAVEFFE 266
            PP+               TEPS        AGGG   P+   +S       + A     
Sbjct: 199 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS--- 255

Query: 267 LLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGPPELEPGLFEPPPAVVGNLLYPEPWSV 326
             GP    GT  A    A P    P G   LR PP++ P   +  PA+    L   P + 
Sbjct: 256 --GPS-ARGTPRA---PAHPSQPKPKGLQALR-PPQVTPPRKDAAPAL--GPLSSSPLAT 306

Query: 327 PGCSPTKKSPLTAPRGGLT-LNEPLSPLYPAAADSPGGEDGRGHLASFAPFFPDC--ALP 383
           P  S TK  P+  P    T L   L P  P A   P        LA  +P  P     LP
Sbjct: 307 PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP--------LAPPSPSAPPSLQTLP 358

Query: 384 PPP--PPHQ 390
            PP  PP Q
Sbjct: 359 SPPATPPSQ 367



 Score = 37.0 bits (84), Expect = 0.034
 Identities = 47/167 (28%), Positives = 60/167 (35%), Gaps = 28/167 (16%)

Query: 108  MGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAH-----------GKAAPRREASQAAA 156
            +   PP PPS S + T +   LA  S+   + P               A+P  +A  AA 
Sbjct: 876  LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 935

Query: 157  AASLQSRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPG 216
              +  SR  A    + R  PG   P       PA G G A       +  GP  AT  PG
Sbjct: 936  HPAAWSRGPAPPL-AFRGAPGAPLP-----WPPATGPGSADGLCTIYETEGPESATPAPG 989

Query: 217  ARKVPLRARNLPPSFFTEPSR----AGGGGCGPSGPDVSLGDLEKGA 259
                   A +  PS  T   +    AG G    S     LG+L  GA
Sbjct: 990  -------ALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGA 1029



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 37/122 (30%), Positives = 44/122 (36%), Gaps = 16/122 (13%)

Query: 106  GLMGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKA----APRREASQAAAAASLQ 161
            G  GA  P PP+           +     P  A PA G      +P     +AAA A   
Sbjct: 952  GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAG 1011

Query: 162  SRSLAALFDSLRHVPGGAEPAGG-----------EVAAPAAGLGGAGTGGA-GGDVAGPA 209
            + S +     L  +P GA  A               A  AAG  G G GGA GG V G A
Sbjct: 1012 ASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGA 1071

Query: 210  GA 211
             A
Sbjct: 1072 RA 1073



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 72/304 (23%), Positives = 97/304 (31%), Gaps = 65/304 (21%)

Query: 110 AAPPGPPSPSAADTPAKRPL--------AAPSAPTVAAPAHGKAAPRREASQAAAAASLQ 161
           A+PP   S S A +P   PL        ++ ++ +  AP      P  E   + A  SLQ
Sbjct: 465 ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524

Query: 162 SRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVP 221
           +   +     L ++P  A P     +AP               +  P   T  P     P
Sbjct: 525 TPPASLTTPPLENLPSLAPPPLQTASAP---------------LTTPHLETP-PCPAPCP 568

Query: 222 LRARNLPPSFFTEPSRAGGGGCG---PSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEA 278
           L+A   PPS  T P            P  P        +G  +     L  P      +A
Sbjct: 569 LQA---PPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPP----PQA 621

Query: 279 AVLLAAEPLDVFPA-----GASVLRGPPELEPGL---------FEPPPAVVGNLLYPEPW 324
              LA  PL   P+       S L  P    P           F PPP+      +  P 
Sbjct: 622 PPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681

Query: 325 SVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADSPGGEDGRGHLASFAPFFPDCALPP 384
           S P  SP+   P  AP    +L  P   + P+   SP             P  P    PP
Sbjct: 682 S-PPVSPSATPPSQAPP---SLAAPPLQVPPSPPASP-------------PMSPSATPPP 724

Query: 385 PPPP 388
             PP
Sbjct: 725 QAPP 728


>gi|22027603 alpha 1 type XIII collagen isoform 16 [Homo sapiens]
          Length = 660

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 101/390 (25%), Positives = 123/390 (31%), Gaps = 82/390 (21%)

Query: 15  PFGFGGSPDGLGGAFGALDKGCCFEDDETGAPAGALLSGAEG--GDVREATRDLLSFIDS 72
           P G  G P G  G  G  D G       TG P      G +G  G   E    LL  ++S
Sbjct: 138 PIGLDGKP-GHPGPKG--DMGL------TGPPGQPGPQGQKGEKGQCGEYPHRLLPLLNS 188

Query: 73  ASSNIKLALDKPGKSKRKVNHRKYLQKQIKRCSGLMGAAPPGPPSPSAADTPAKR----- 127
                 + L  P   KR+    +  Q  I+         PPGPP P     P        
Sbjct: 189 ------VRLAPPPVIKRRTFQGEQSQASIQ--------GPPGPPGPPGPSGPLGHPGLPG 234

Query: 128 PLAAPSAPTVAAPA--------HGKAAPRREASQAAAAASLQSRSLA-ALFDSLRHVPGG 178
           P+  P  P    P         HG+   R          +  +  +A A       +PG 
Sbjct: 235 PMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGT 294

Query: 179 AEPAGGEVAAPAAGL-------GGAGTG-GAGGDVAGPAGATAIPGAR-KVPLRARNLPP 229
               G E +    GL       G AG   G G    GP G    PG + +  +  +  PP
Sbjct: 295 KGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDGQVGPP 354

Query: 230 SFFTEPSRAGGGG-CGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLD 288
               +    G  G  GP GP  S G+  KG            DY      A+        
Sbjct: 355 GQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMV---------DYNGNINEALQ------- 398

Query: 289 VFPAGASVLRGPPELEPGLFEPP-----PAVVGNLLYPEPWSVPGCSPTKKSPLTAPRGG 343
                   L GPP L PG   PP     P   G +  P P   PG    K      PRG 
Sbjct: 399 --EIRTLALMGPPGL-PGQIGPPGAPGIPGQKGEIGLPGP---PGHDGEK-----GPRGK 447

Query: 344 LTLNEPLSPLYPAAADSPGGEDG-RGHLAS 372
                P  P  P   D P G  G  GH  S
Sbjct: 448 PGDMGPPGPQGPPGKDGPPGVKGENGHPGS 477


>gi|22027593 alpha 1 type XIII collagen isoform 11 [Homo sapiens]
          Length = 686

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 101/390 (25%), Positives = 123/390 (31%), Gaps = 82/390 (21%)

Query: 15  PFGFGGSPDGLGGAFGALDKGCCFEDDETGAPAGALLSGAEG--GDVREATRDLLSFIDS 72
           P G  G P G  G  G  D G       TG P      G +G  G   E    LL  ++S
Sbjct: 176 PIGLDGKP-GHPGPKG--DMGL------TGPPGQPGPQGQKGEKGQCGEYPHRLLPLLNS 226

Query: 73  ASSNIKLALDKPGKSKRKVNHRKYLQKQIKRCSGLMGAAPPGPPSPSAADTPAKR----- 127
                 + L  P   KR+    +  Q  I+         PPGPP P     P        
Sbjct: 227 ------VRLAPPPVIKRRTFQGEQSQASIQ--------GPPGPPGPPGPSGPLGHPGLPG 272

Query: 128 PLAAPSAPTVAAPA--------HGKAAPRREASQAAAAASLQSRSLA-ALFDSLRHVPGG 178
           P+  P  P    P         HG+   R          +  +  +A A       +PG 
Sbjct: 273 PMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGT 332

Query: 179 AEPAGGEVAAPAAGL-------GGAGTG-GAGGDVAGPAGATAIPGAR-KVPLRARNLPP 229
               G E +    GL       G AG   G G    GP G    PG + +  +  +  PP
Sbjct: 333 KGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDGQVGPP 392

Query: 230 SFFTEPSRAGGGG-CGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLD 288
               +    G  G  GP GP  S G+  KG            DY      A+        
Sbjct: 393 GQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMV---------DYNGNINEALQ------- 436

Query: 289 VFPAGASVLRGPPELEPGLFEPP-----PAVVGNLLYPEPWSVPGCSPTKKSPLTAPRGG 343
                   L GPP L PG   PP     P   G +  P P   PG    K      PRG 
Sbjct: 437 --EIRTLALMGPPGL-PGQIGPPGAPGIPGQKGEIGLPGP---PGHDGEK-----GPRGK 485

Query: 344 LTLNEPLSPLYPAAADSPGGEDG-RGHLAS 372
                P  P  P   D P G  G  GH  S
Sbjct: 486 PGDMGPPGPQGPPGKDGPPGVKGENGHPGS 515


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.135    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,449,750
Number of Sequences: 37866
Number of extensions: 1573304
Number of successful extensions: 17802
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 259
Number of HSP's successfully gapped in prelim test: 1138
Number of HSP's that attempted gapping in prelim test: 11128
Number of HSP's gapped (non-prelim): 5604
length of query: 426
length of database: 18,247,518
effective HSP length: 105
effective length of query: 321
effective length of database: 14,271,588
effective search space: 4581179748
effective search space used: 4581179748
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press