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Search of human proteins with 54607068
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54607068 calcium channel, voltage-dependent, beta 4 subunit
isoform a [Homo sapiens]
(486 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54607068 calcium channel, voltage-dependent, beta 4 subunit i... 967 0.0
gi|54607066 calcium channel, voltage-dependent, beta 4 subunit i... 936 0.0
gi|54607064 calcium channel, voltage-dependent, beta 4 subunit i... 936 0.0
gi|224831262 calcium channel, voltage-dependent, beta 4 subunit ... 763 0.0
gi|147901383 calcium channel, voltage-dependent, beta 2 subunit ... 639 0.0
gi|40316928 calcium channel, voltage-dependent, beta 3 subunit [... 622 e-178
gi|147904948 calcium channel, voltage-dependent, beta 2 subunit ... 619 e-177
gi|45359842 calcium channel, voltage-dependent, beta 2 subunit i... 619 e-177
gi|45359834 calcium channel, voltage-dependent, beta 2 subunit i... 613 e-176
gi|148223541 calcium channel, voltage-dependent, beta 2 subunit ... 613 e-176
gi|148226485 calcium channel, voltage-dependent, beta 2 subunit ... 613 e-176
gi|147898681 calcium channel, voltage-dependent, beta 2 subunit ... 613 e-176
gi|148232726 calcium channel, voltage-dependent, beta 2 subunit ... 613 e-176
gi|40804468 calcium channel, voltage-dependent, beta 1 subunit i... 606 e-173
gi|40804472 calcium channel, voltage-dependent, beta 1 subunit i... 605 e-173
gi|40804470 calcium channel, voltage-dependent, beta 1 subunit i... 574 e-164
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi... 52 9e-07
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi... 50 4e-06
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens] 49 8e-06
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi... 44 3e-04
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa... 44 3e-04
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens] 44 4e-04
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 41 0.002
gi|218156270 chapsyn-110 isoform 4 [Homo sapiens] 41 0.002
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens] 40 0.004
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens] 40 0.004
gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens] 39 0.008
gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens] 37 0.031
gi|186700629 calcium/calmodulin-dependent serine protein kinase ... 36 0.090
gi|186700627 calcium/calmodulin-dependent serine protein kinase ... 36 0.090
>gi|54607068 calcium channel, voltage-dependent, beta 4 subunit
isoform a [Homo sapiens]
Length = 486
Score = 967 bits (2501), Expect = 0.0
Identities = 486/486 (100%), Positives = 486/486 (100%)
Query: 1 MYDNLYLHGIEDSEAGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVA 60
MYDNLYLHGIEDSEAGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVA
Sbjct: 1 MYDNLYLHGIEDSEAGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVA 60
Query: 61 FAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSP 120
FAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSP
Sbjct: 61 FAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSP 120
Query: 121 LRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYD 180
LRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYD
Sbjct: 121 LRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYD 180
Query: 181 VVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNP 240
VVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNP
Sbjct: 181 VVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNP 240
Query: 241 SKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHV 300
SKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHV
Sbjct: 241 SKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHV 300
Query: 301 KVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEY 360
KVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEY
Sbjct: 301 KVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEY 360
Query: 361 LEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRS 420
LEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRS
Sbjct: 361 LEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRS 420
Query: 421 LMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSH 480
LMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSH
Sbjct: 421 LMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSH 480
Query: 481 DSRHRL 486
DSRHRL
Sbjct: 481 DSRHRL 486
>gi|54607066 calcium channel, voltage-dependent, beta 4 subunit
isoform c [Homo sapiens]
Length = 502
Score = 936 bits (2420), Expect = 0.0
Identities = 471/471 (100%), Positives = 471/471 (100%)
Query: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75
GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE
Sbjct: 32 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 91
Query: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRG 135
DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRG
Sbjct: 92 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRG 151
Query: 136 RFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSL 195
RFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSL
Sbjct: 152 RFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSL 211
Query: 196 KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL 255
KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL
Sbjct: 212 KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL 271
Query: 256 AEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSR 315
AEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSR
Sbjct: 272 AEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSR 331
Query: 316 GKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTP 375
GKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTP
Sbjct: 332 GKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTP 391
Query: 376 MTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARK 435
MTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARK
Sbjct: 392 MTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARK 451
Query: 436 SRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 486
SRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL
Sbjct: 452 SRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 502
>gi|54607064 calcium channel, voltage-dependent, beta 4 subunit
isoform b [Homo sapiens]
Length = 520
Score = 936 bits (2420), Expect = 0.0
Identities = 471/471 (100%), Positives = 471/471 (100%)
Query: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75
GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE
Sbjct: 50 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 109
Query: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRG 135
DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRG
Sbjct: 110 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRG 169
Query: 136 RFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSL 195
RFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSL
Sbjct: 170 RFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSL 229
Query: 196 KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL 255
KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL
Sbjct: 230 KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL 289
Query: 256 AEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSR 315
AEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSR
Sbjct: 290 AEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSR 349
Query: 316 GKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTP 375
GKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTP
Sbjct: 350 GKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTP 409
Query: 376 MTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARK 435
MTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARK
Sbjct: 410 MTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARK 469
Query: 436 SRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 486
SRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL
Sbjct: 470 SRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 520
>gi|224831262 calcium channel, voltage-dependent, beta 4 subunit
isoform d [Homo sapiens]
Length = 458
Score = 763 bits (1969), Expect = 0.0
Identities = 402/471 (85%), Positives = 403/471 (85%), Gaps = 62/471 (13%)
Query: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75
GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE
Sbjct: 50 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 109
Query: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRG 135
DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRG
Sbjct: 110 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRG 169
Query: 136 RFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSL 195
RFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSL
Sbjct: 170 RFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSL 229
Query: 196 KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL 255
KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL
Sbjct: 230 KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL 289
Query: 256 AEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSR 315
AEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSR
Sbjct: 290 AEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSR 349
Query: 316 GKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTP 375
GKSQSKHLNVQLVAADKLAQCPP R H+ ST
Sbjct: 350 GKSQSKHLNVQLVAADKLAQCPPSQ-------------------------RMRHSNHST- 383
Query: 376 MTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARK 435
ENSPIERRSLMTSDENYHNERARK
Sbjct: 384 ------------------------------------ENSPIERRSLMTSDENYHNERARK 407
Query: 436 SRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 486
SRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL
Sbjct: 408 SRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 458
>gi|147901383 calcium channel, voltage-dependent, beta 2 subunit
isoform 5 [Homo sapiens]
Length = 622
Score = 639 bits (1649), Expect = 0.0
Identities = 341/499 (68%), Positives = 392/499 (78%), Gaps = 29/499 (5%)
Query: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75
GSADSYTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNVSY A ++
Sbjct: 72 GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 131
Query: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQ--K 133
DVPVP AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+Q EQ K
Sbjct: 132 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 191
Query: 134 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGP 193
+G+F+ KS GNSSSSLG++V + ++TP S+AKQKQK TEH PPYDVVPSMRPVVLVGP
Sbjct: 192 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQKQKSTEHTPPYDVVPSMRPVVLVGP 251
Query: 194 SLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRS 253
SLKGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRS
Sbjct: 252 SLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRS 311
Query: 254 SLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIK 313
SLAEVQSEIERIFELAR+LQLVVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIK
Sbjct: 312 SLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIK 371
Query: 314 SRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSS 373
SRGKSQ+KHLNVQ+VAADKLAQCPPE+FDVILDENQLEDACEHL +YLEAYW+ATH SS
Sbjct: 372 SRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSS 431
Query: 374 TPMTPLLGRNLGSTALSPYPTAISGLQ----------SQRMRHSNHSTENSPIE----RR 419
+ PLL R L +++L PT S Q S +R ++ + E +E +
Sbjct: 432 SLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQ 491
Query: 420 SLMTSDENYHNERARKSR-----NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-- 471
+S +HN R+ SR S +Q SRD Y +EDY + D Y HR+
Sbjct: 492 HRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHN 551
Query: 472 -----RGSPGGYSHDSRHR 485
GS +SRHR
Sbjct: 552 HRDETHGSSDHRHRESRHR 570
>gi|40316928 calcium channel, voltage-dependent, beta 3 subunit
[Homo sapiens]
Length = 484
Score = 622 bits (1604), Expect = e-178
Identities = 341/489 (69%), Positives = 380/489 (77%), Gaps = 33/489 (6%)
Query: 1 MYDNLYLHGIEDSEAGSADSYTSRPS-DSDVSLEEDREAIRQEREQQAAIQLERAKSKPV 59
MYD+ Y+ G EDSEAGSADSYTSRPS DSDVSLEEDRE+ R+E E QA QLERAK KPV
Sbjct: 1 MYDDSYVPGFEDSEAGSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPV 60
Query: 60 AFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPS 119
AFAV+TNVSYCG LDE+ PV + ++F+AKDFLHIKEKY+NDWWIGRLVKEG +I FIPS
Sbjct: 61 AFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPS 120
Query: 120 PLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPY 179
P RLE+IR++QEQK R SGN SS L ++ G R+ P S AKQKQK EH+PPY
Sbjct: 121 PQRLESIRLKQEQKARR------SGNPSS-LSDI--GNRRSPPPSLAKQKQKQAEHVPPY 171
Query: 180 DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNN 239
DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD+SLAKRSVLNN
Sbjct: 172 DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNN 231
Query: 240 PSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVH 299
P KR IIERS+ RSS+AEVQSEIERIFELA+SLQLVVLDADTINHPAQL KTSLAPIIV
Sbjct: 232 PGKRTIIERSSARSSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVF 291
Query: 300 VKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGE 359
VKVSSPKVLQRLI+SRGKSQ KHL VQ++A DKL QCPPE FDVILDENQLEDACEHL E
Sbjct: 292 VKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAE 351
Query: 360 YLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERR 419
YLE YWRATH + P LLG P+AI GLQ+Q++ E+SP+ER
Sbjct: 352 YLEVYWRATHHPAPGP--GLLGP----------PSAIPGLQNQQLL-GERGEEHSPLERD 398
Query: 420 SLMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNR--GSPGG 477
SLM SD E + SR + SSQ S H +EEDY D+YQD Y+PHR G P
Sbjct: 399 SLMPSD-----EASESSRQAWTGSSQRSSRH---LEEDYADAYQDLYQPHRQHTSGLPSA 450
Query: 478 YSHDSRHRL 486
HD + RL
Sbjct: 451 NGHDPQDRL 459
>gi|147904948 calcium channel, voltage-dependent, beta 2 subunit
isoform 8 [Homo sapiens]
Length = 608
Score = 619 bits (1595), Expect = e-177
Identities = 335/513 (65%), Positives = 387/513 (75%), Gaps = 43/513 (8%)
Query: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75
GSADSYTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNVSY A ++
Sbjct: 44 GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 103
Query: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQ--K 133
DVPVP AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+Q EQ K
Sbjct: 104 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 163
Query: 134 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQK--------------VTEHIPPY 179
+G+F+ KS GNSSSSLG++V + ++TP S+ + TEH PPY
Sbjct: 164 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAKSADEQDQWKTAGLFWRFTTEHTPPY 223
Query: 180 DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNN 239
DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNN
Sbjct: 224 DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNN 283
Query: 240 PSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVH 299
PSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLVVLDADTINHPAQL KTSLAPIIV+
Sbjct: 284 PSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVY 343
Query: 300 VKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGE 359
VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQCPPE+FDVILDENQLEDACEHL +
Sbjct: 344 VKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLAD 403
Query: 360 YLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQ----------SQRMRHSNH 409
YLEAYW+ATH SS+ PLL R L +++L PT S Q S +R ++
Sbjct: 404 YLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQ 463
Query: 410 STENSPIE----RRSLMTSDENYHNERARKSR-----NRLSSSSQHSRDH-YPLVEEDYP 459
+ E +E + +S +HN R+ SR S +Q SRD Y +EDY
Sbjct: 464 AEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYS 523
Query: 460 DSYQDTYKPHRN-------RGSPGGYSHDSRHR 485
+ D Y HR+ GS +SRHR
Sbjct: 524 HDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 556
>gi|45359842 calcium channel, voltage-dependent, beta 2 subunit
isoform 4 [Homo sapiens]
Length = 636
Score = 619 bits (1595), Expect = e-177
Identities = 335/513 (65%), Positives = 387/513 (75%), Gaps = 43/513 (8%)
Query: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75
GSADSYTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNVSY A ++
Sbjct: 72 GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 131
Query: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQ--K 133
DVPVP AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+Q EQ K
Sbjct: 132 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 191
Query: 134 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQK--------------VTEHIPPY 179
+G+F+ KS GNSSSSLG++V + ++TP S+ + TEH PPY
Sbjct: 192 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAKSADEQDQWKTAGLFWRFTTEHTPPY 251
Query: 180 DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNN 239
DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNN
Sbjct: 252 DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNN 311
Query: 240 PSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVH 299
PSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLVVLDADTINHPAQL KTSLAPIIV+
Sbjct: 312 PSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVY 371
Query: 300 VKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGE 359
VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQCPPE+FDVILDENQLEDACEHL +
Sbjct: 372 VKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLAD 431
Query: 360 YLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQ----------SQRMRHSNH 409
YLEAYW+ATH SS+ PLL R L +++L PT S Q S +R ++
Sbjct: 432 YLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQ 491
Query: 410 STENSPIE----RRSLMTSDENYHNERARKSR-----NRLSSSSQHSRDH-YPLVEEDYP 459
+ E +E + +S +HN R+ SR S +Q SRD Y +EDY
Sbjct: 492 AEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYS 551
Query: 460 DSYQDTYKPHRN-------RGSPGGYSHDSRHR 485
+ D Y HR+ GS +SRHR
Sbjct: 552 HDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 584
>gi|45359834 calcium channel, voltage-dependent, beta 2 subunit
isoform 7 [Homo sapiens]
Length = 612
Score = 613 bits (1582), Expect = e-176
Identities = 339/537 (63%), Positives = 392/537 (72%), Gaps = 67/537 (12%)
Query: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75
GSADSYTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNVSY A ++
Sbjct: 24 GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 83
Query: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQ--K 133
DVPVP AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+Q EQ K
Sbjct: 84 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 143
Query: 134 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA--------------------------- 166
+G+F+ KS GNSSSSLG++V + ++TP S+A
Sbjct: 144 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 203
Query: 167 -------KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 215
K+K+ K TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 204 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 263
Query: 216 FDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLV 275
F+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLV
Sbjct: 264 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 323
Query: 276 VLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQ 335
VLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQ
Sbjct: 324 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 383
Query: 336 CPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTA 395
CPPE+FDVILDENQLEDACEHL +YLEAYW+ATH SS+ PLL R L +++L PT
Sbjct: 384 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 443
Query: 396 ISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR---- 437
S Q S +R ++ + E +E + +S +HN R+ SR
Sbjct: 444 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 503
Query: 438 -NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 485
S +Q SRD Y +EDY + D Y HR+ GS +SRHR
Sbjct: 504 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 560
>gi|148223541 calcium channel, voltage-dependent, beta 2 subunit
isoform 6 [Homo sapiens]
Length = 632
Score = 613 bits (1582), Expect = e-176
Identities = 339/537 (63%), Positives = 392/537 (72%), Gaps = 67/537 (12%)
Query: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75
GSADSYTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNVSY A ++
Sbjct: 44 GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 103
Query: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQ--K 133
DVPVP AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+Q EQ K
Sbjct: 104 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 163
Query: 134 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA--------------------------- 166
+G+F+ KS GNSSSSLG++V + ++TP S+A
Sbjct: 164 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 223
Query: 167 -------KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 215
K+K+ K TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 224 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 283
Query: 216 FDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLV 275
F+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLV
Sbjct: 284 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 343
Query: 276 VLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQ 335
VLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQ
Sbjct: 344 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 403
Query: 336 CPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTA 395
CPPE+FDVILDENQLEDACEHL +YLEAYW+ATH SS+ PLL R L +++L PT
Sbjct: 404 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 463
Query: 396 ISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR---- 437
S Q S +R ++ + E +E + +S +HN R+ SR
Sbjct: 464 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 523
Query: 438 -NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 485
S +Q SRD Y +EDY + D Y HR+ GS +SRHR
Sbjct: 524 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 580
>gi|148226485 calcium channel, voltage-dependent, beta 2 subunit
isoform 3 [Homo sapiens]
Length = 606
Score = 613 bits (1582), Expect = e-176
Identities = 339/537 (63%), Positives = 392/537 (72%), Gaps = 67/537 (12%)
Query: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75
GSADSYTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNVSY A ++
Sbjct: 18 GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 77
Query: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQ--K 133
DVPVP AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+Q EQ K
Sbjct: 78 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 137
Query: 134 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA--------------------------- 166
+G+F+ KS GNSSSSLG++V + ++TP S+A
Sbjct: 138 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 197
Query: 167 -------KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 215
K+K+ K TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 198 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 257
Query: 216 FDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLV 275
F+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLV
Sbjct: 258 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 317
Query: 276 VLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQ 335
VLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQ
Sbjct: 318 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 377
Query: 336 CPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTA 395
CPPE+FDVILDENQLEDACEHL +YLEAYW+ATH SS+ PLL R L +++L PT
Sbjct: 378 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 437
Query: 396 ISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR---- 437
S Q S +R ++ + E +E + +S +HN R+ SR
Sbjct: 438 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 497
Query: 438 -NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 485
S +Q SRD Y +EDY + D Y HR+ GS +SRHR
Sbjct: 498 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 554
>gi|147898681 calcium channel, voltage-dependent, beta 2 subunit
isoform 2 [Homo sapiens]
Length = 660
Score = 613 bits (1582), Expect = e-176
Identities = 339/537 (63%), Positives = 392/537 (72%), Gaps = 67/537 (12%)
Query: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75
GSADSYTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNVSY A ++
Sbjct: 72 GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 131
Query: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQ--K 133
DVPVP AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+Q EQ K
Sbjct: 132 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 191
Query: 134 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA--------------------------- 166
+G+F+ KS GNSSSSLG++V + ++TP S+A
Sbjct: 192 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 251
Query: 167 -------KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 215
K+K+ K TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 252 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 311
Query: 216 FDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLV 275
F+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLV
Sbjct: 312 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 371
Query: 276 VLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQ 335
VLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQ
Sbjct: 372 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 431
Query: 336 CPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTA 395
CPPE+FDVILDENQLEDACEHL +YLEAYW+ATH SS+ PLL R L +++L PT
Sbjct: 432 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 491
Query: 396 ISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR---- 437
S Q S +R ++ + E +E + +S +HN R+ SR
Sbjct: 492 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 551
Query: 438 -NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 485
S +Q SRD Y +EDY + D Y HR+ GS +SRHR
Sbjct: 552 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 608
>gi|148232726 calcium channel, voltage-dependent, beta 2 subunit
isoform 1 [Homo sapiens]
Length = 605
Score = 613 bits (1582), Expect = e-176
Identities = 339/537 (63%), Positives = 392/537 (72%), Gaps = 67/537 (12%)
Query: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75
GSADSYTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNVSY A ++
Sbjct: 17 GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 76
Query: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQ--K 133
DVPVP AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+Q EQ K
Sbjct: 77 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 136
Query: 134 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA--------------------------- 166
+G+F+ KS GNSSSSLG++V + ++TP S+A
Sbjct: 137 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 196
Query: 167 -------KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 215
K+K+ K TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 197 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 256
Query: 216 FDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLV 275
F+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLV
Sbjct: 257 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 316
Query: 276 VLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQ 335
VLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQ
Sbjct: 317 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 376
Query: 336 CPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTA 395
CPPE+FDVILDENQLEDACEHL +YLEAYW+ATH SS+ PLL R L +++L PT
Sbjct: 377 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 436
Query: 396 ISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR---- 437
S Q S +R ++ + E +E + +S +HN R+ SR
Sbjct: 437 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 496
Query: 438 -NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 485
S +Q SRD Y +EDY + D Y HR+ GS +SRHR
Sbjct: 497 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 553
>gi|40804468 calcium channel, voltage-dependent, beta 1 subunit
isoform 1 [Homo sapiens]
Length = 598
Score = 606 bits (1563), Expect = e-173
Identities = 303/408 (74%), Positives = 349/408 (85%), Gaps = 2/408 (0%)
Query: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75
GSA+SYTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNV Y + +
Sbjct: 58 GSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGD 117
Query: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQK-- 133
+VPV AI+F+ KDFLHIKEKYNNDWWIGRLVKEGCE+GFIPSP++L+++R+ QEQK
Sbjct: 118 EVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLR 177
Query: 134 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGP 193
+ R KS NSSSSLG++V+GT R TP ++AKQKQK TEH+PPYDVVPSMRP++LVGP
Sbjct: 178 QNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGP 237
Query: 194 SLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRS 253
SLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSK IIERSNTRS
Sbjct: 238 SLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRS 297
Query: 254 SLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIK 313
SLAEVQSEIERIFELAR+LQLV LDADTINHPAQL KTSLAPIIV++K++SPKVLQRLIK
Sbjct: 298 SLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIK 357
Query: 314 SRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSS 373
SRGKSQSKHLNVQ+ A++KLAQCPPEMFD+ILDENQLEDACEHL EYLEAYW+ATH SS
Sbjct: 358 SRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSS 417
Query: 374 TPMTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSL 421
TP PLL R + + AL+ P +S LQ + + E + E S+
Sbjct: 418 TPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQPLERATGEHASM 465
>gi|40804472 calcium channel, voltage-dependent, beta 1 subunit
isoform 3 [Homo sapiens]
Length = 478
Score = 605 bits (1559), Expect = e-173
Identities = 301/389 (77%), Positives = 343/389 (88%), Gaps = 2/389 (0%)
Query: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75
GSA+SYTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNV Y + +
Sbjct: 58 GSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGD 117
Query: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQK-- 133
+VPV AI+F+ KDFLHIKEKYNNDWWIGRLVKEGCE+GFIPSP++L+++R+ QEQK
Sbjct: 118 EVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLR 177
Query: 134 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGP 193
+ R KS NSSSSLG++V+GT R TP ++AKQKQK TEH+PPYDVVPSMRP++LVGP
Sbjct: 178 QNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGP 237
Query: 194 SLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRS 253
SLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSK IIERSNTRS
Sbjct: 238 SLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRS 297
Query: 254 SLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIK 313
SLAEVQSEIERIFELAR+LQLV LDADTINHPAQL KTSLAPIIV++K++SPKVLQRLIK
Sbjct: 298 SLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIK 357
Query: 314 SRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSS 373
SRGKSQSKHLNVQ+ A++KLAQCPPEMFD+ILDENQLEDACEHL EYLEAYW+ATH SS
Sbjct: 358 SRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSS 417
Query: 374 TPMTPLLGRNLGSTALSPYPTAISGLQSQ 402
TP PLL R + + AL+ P +S LQ Q
Sbjct: 418 TPPNPLLNRTMATAALAASPAPVSNLQVQ 446
>gi|40804470 calcium channel, voltage-dependent, beta 1 subunit
isoform 2 [Homo sapiens]
Length = 523
Score = 574 bits (1479), Expect = e-164
Identities = 296/434 (68%), Positives = 339/434 (78%), Gaps = 47/434 (10%)
Query: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75
GSA+SYTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNV Y + +
Sbjct: 58 GSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGD 117
Query: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQK-- 133
+VPV AI+F+ KDFLHIKEKYNNDWWIGRLVKEGCE+GFIPSP++L+++R+ QEQK
Sbjct: 118 EVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLR 177
Query: 134 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQ----------------------- 170
+ R KS NSSSSLG++V+GT R TP ++ +
Sbjct: 178 QNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGEQSG 237
Query: 171 ----------------------KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL 208
K TEH+PPYDVVPSMRP++LVGPSLKGYEVTDMMQKAL
Sbjct: 238 SAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKAL 297
Query: 209 FDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFEL 268
FDFLKHRFDGRISITRVTADISLAKRSVLNNPSK IIERSNTRSSLAEVQSEIERIFEL
Sbjct: 298 FDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFEL 357
Query: 269 ARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLV 328
AR+LQLV LDADTINHPAQL KTSLAPIIV++K++SPKVLQRLIKSRGKSQSKHLNVQ+
Sbjct: 358 ARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIA 417
Query: 329 AADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTA 388
A++KLAQCPPEMFD+ILDENQLEDACEHL EYLEAYW+ATH SSTP PLL R + + A
Sbjct: 418 ASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAA 477
Query: 389 LSPYPTAISGLQSQ 402
L+ P +S LQ Q
Sbjct: 478 LAASPAPVSNLQVQ 491
>gi|119943106 synapse-associated protein 102 isoform a [Homo
sapiens]
Length = 817
Score = 52.4 bits (124), Expect = 9e-07
Identities = 67/301 (22%), Positives = 121/301 (40%), Gaps = 29/301 (9%)
Query: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQEQ 132
D +PS +SF D LH+ +++WW RLV E +IG IPS R+E + +
Sbjct: 517 DSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEK-KERARL 575
Query: 133 KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIP-PYDVVPSMRPVVLV 191
K +FH S+ + + A + Q+ + + P + RPV+++
Sbjct: 576 KTVKFHARTGMIESNRDFPGLSDDYYGA--KNLKGQEDAILSYEPVTRQEIHYARPVIIL 633
Query: 192 GPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTAD---------ISLAKRSVLNNPS 241
GP + D + L H+F + TR D +++ + +
Sbjct: 634 GP------MKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQ 687
Query: 242 KRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVK 301
IE +L + I+ + +A + +LD N +L + L PI + +K
Sbjct: 688 DNKFIEAGQFNDNL--YGTSIQSVRAVAERGKHCILDVSG-NAIKRLQQAQLYPIAIFIK 744
Query: 302 VSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYL 361
PK ++ L++ + + N A KL Q E F I+ + LE+ + + +
Sbjct: 745 ---PKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQII 801
Query: 362 E 362
E
Sbjct: 802 E 802
>gi|119943108 synapse-associated protein 102 isoform b [Homo
sapiens]
Length = 512
Score = 50.4 bits (119), Expect = 4e-06
Identities = 72/330 (21%), Positives = 130/330 (39%), Gaps = 55/330 (16%)
Query: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLE-------- 124
D +PS +SF D LH+ +++WW RLV E +IG IPS R+E
Sbjct: 180 DSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLK 239
Query: 125 -------------NIRIQQEQKRG-------RFHGGKSSGNSSSSLGEM-VSGTFRATPT 163
N I+ ++K+ F+ K + SS+ E V+ + +
Sbjct: 240 TVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSES 299
Query: 164 STAKQKQKVTEHIP-PYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-S 221
S+ Q+ + + P + RPV+++GP + D + L H+F +
Sbjct: 300 SSKGQEDAILSYEPVTRQEIHYARPVIILGP------MKDRVNDDLISEFPHKFGSCVPH 353
Query: 222 ITRVTAD---------ISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSL 272
TR D +++ + + IE +L + I+ + +A
Sbjct: 354 TTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNL--YGTSIQSVRAVAERG 411
Query: 273 QLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADK 332
+ +LD N +L + L PI + +K PK ++ L++ + + N A K
Sbjct: 412 KHCILDVSG-NAIKRLQQAQLYPIAIFIK---PKSIEALMEMNRRQTYEQANKIYDKAMK 467
Query: 333 LAQCPPEMFDVILDENQLEDACEHLGEYLE 362
L Q E F I+ + LE+ + + +E
Sbjct: 468 LEQEFGEYFTAIVQGDSLEEIYNKIKQIIE 497
>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
Length = 904
Score = 49.3 bits (116), Expect = 8e-06
Identities = 63/307 (20%), Positives = 122/307 (39%), Gaps = 32/307 (10%)
Query: 75 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 131
+D +PS ++F D LH+ +++WW R V E E+G IPS R+E + +
Sbjct: 596 KDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEK-KERAR 654
Query: 132 QKRGRFHG-GKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSM----- 185
K +F+ + G +G + + + + E++ Y+ V
Sbjct: 655 LKTVKFNSKTRDKGEIPDDMGSKGLKHVTSNASDSESSYRGQEEYVLSYEPVNQQEVNYT 714
Query: 186 RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADISL---------AKRS 235
RPV+++GP + D + L +F + TR D + ++
Sbjct: 715 RPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQ 768
Query: 236 VLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAP 295
+ + + IE + L + ++ + E+A + +LD N +L L P
Sbjct: 769 MEKDIQEHKFIEAGQYNNHL--YGTSVQSVREVAEKGKHCILDVSG-NAIKRLQIAQLYP 825
Query: 296 IIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACE 355
I + +K PK ++ +++ + + A KL Q E F I+ + LED
Sbjct: 826 ISIFIK---PKSMENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYN 882
Query: 356 HLGEYLE 362
+ + +E
Sbjct: 883 QVKQIIE 889
>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
sapiens]
Length = 767
Score = 44.3 bits (103), Expect = 3e-04
Identities = 70/301 (23%), Positives = 118/301 (39%), Gaps = 59/301 (19%)
Query: 81 STAISFDAKDFLHIKEKYNNDWWIGRLV---KEGCEIGFIPSPLRLENIRIQQEQKRGRF 137
S A+SF D LH+ + + +WW R V E +IGFIPS R+E ++E R +
Sbjct: 492 SQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVE----RREWSRLK- 546
Query: 138 HGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKG 197
K G+SS S G S T T V RP++++GP+ K
Sbjct: 547 --AKDWGSSSGSQGREDSVLSYETVTQME---------------VHYARPIIILGPT-KD 588
Query: 198 YEVTDMMQKALFDF-----------LKHRFDGR-----ISITRVTADISLAKRSVLNNPS 241
D++ + F ++ DGR S ++ DI K
Sbjct: 589 RANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHK-------- 640
Query: 242 KRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVK 301
IE S L + ++ + E+A + +LD + N +L L PI + ++
Sbjct: 641 ---FIEAGQYNSHL--YGTSVQSVREVAEQGKHCILDV-SANAVRRLQAAHLHPIAIFIR 694
Query: 302 VSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYL 361
P+ L+ +++ + + A KL Q E F I++ + E+ + +
Sbjct: 695 ---PRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVI 751
Query: 362 E 362
E
Sbjct: 752 E 752
>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
sapiens]
Length = 721
Score = 44.3 bits (103), Expect = 3e-04
Identities = 70/301 (23%), Positives = 118/301 (39%), Gaps = 59/301 (19%)
Query: 81 STAISFDAKDFLHIKEKYNNDWWIGRLV---KEGCEIGFIPSPLRLENIRIQQEQKRGRF 137
S A+SF D LH+ + + +WW R V E +IGFIPS R+E ++E R +
Sbjct: 446 SQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVE----RREWSRLK- 500
Query: 138 HGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKG 197
K G+SS S G S T T V RP++++GP+ K
Sbjct: 501 --AKDWGSSSGSQGREDSVLSYETVTQME---------------VHYARPIIILGPT-KD 542
Query: 198 YEVTDMMQKALFDF-----------LKHRFDGR-----ISITRVTADISLAKRSVLNNPS 241
D++ + F ++ DGR S ++ DI K
Sbjct: 543 RANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHK-------- 594
Query: 242 KRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVK 301
IE S L + ++ + E+A + +LD + N +L L PI + ++
Sbjct: 595 ---FIEAGQYNSHL--YGTSVQSVREVAEQGKHCILDV-SANAVRRLQAAHLHPIAIFIR 648
Query: 302 VSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYL 361
P+ L+ +++ + + A KL Q E F I++ + E+ + +
Sbjct: 649 ---PRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVI 705
Query: 362 E 362
E
Sbjct: 706 E 706
>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
Length = 926
Score = 43.5 bits (101), Expect = 4e-04
Identities = 67/328 (20%), Positives = 127/328 (38%), Gaps = 52/328 (15%)
Query: 75 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRL---ENIRI 128
+D +PS ++F D LH+ +++WW R V E E+G IPS R+ E R+
Sbjct: 596 KDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARL 655
Query: 129 Q------QEQKRGRFHGGKSSGN-----------------SSSSLGEMVSGTFRATPTST 165
+ + + +G+ K N +S + V+ + +S
Sbjct: 656 KTVKFNSKTRDKGQSFNDKRKKNLFSRKFPFYKNKDQSEQETSDADQHVTSNASDSESSY 715
Query: 166 AKQKQKVTEHIP-PYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SIT 223
Q++ V + P V RPV+++GP + D + L +F + T
Sbjct: 716 RGQEEYVLSYEPVNQQEVNYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTT 769
Query: 224 RVTADISL---------AKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQL 274
R D + ++ + + + IE + L + ++ + E+A +
Sbjct: 770 RPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHL--YGTSVQSVREVAEKGKH 827
Query: 275 VVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLA 334
+LD N +L L PI + +K PK ++ +++ + + A KL
Sbjct: 828 CILDVSG-NAIKRLQIAQLYPISIFIK---PKSMENIMEMNKRLTEEQARKTFERAMKLE 883
Query: 335 QCPPEMFDVILDENQLEDACEHLGEYLE 362
Q E F I+ + LED + + +E
Sbjct: 884 QEFTEHFTAIVQGDTLEDIYNQVKQIIE 911
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 41.2 bits (95), Expect = 0.002
Identities = 66/295 (22%), Positives = 118/295 (40%), Gaps = 35/295 (11%)
Query: 75 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 131
+D +PS +SF D LH+ +++WW R V + E+G IPS R+E + +
Sbjct: 448 KDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVER-KERAR 506
Query: 132 QKRGRFH---GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIP-PYDVVPSMRP 187
K +F+ G S LG+ GT + Q+ + + P + RP
Sbjct: 507 LKTVKFNAKPGVIDSKGDIPGLGDDGYGT-----KTLRGQEDLILSYEPVTRQEINYTRP 561
Query: 188 VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADIS---------LAKRSVL 237
V+++GP + D + L +F + TR D +++ +
Sbjct: 562 VIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQME 615
Query: 238 NNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPII 297
+ + IE +L + ++ + +A + +LD N +L L PI
Sbjct: 616 KDIQEHKFIEAGQYNDNL--YGTSVQSVRFVAERGKHCILDVSG-NAIKRLQVAQLYPIA 672
Query: 298 VHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLED 352
+ +K S + L + K + Q+K + + KL Q E F I+ + LED
Sbjct: 673 IFIKPRSLEPLMEMNKRLTEEQAKKTYDRAI---KLEQEFGEYFTAIVQGDTLED 724
>gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]
Length = 334
Score = 41.2 bits (95), Expect = 0.002
Identities = 66/295 (22%), Positives = 118/295 (40%), Gaps = 35/295 (11%)
Query: 75 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 131
+D +PS +SF D LH+ +++WW R V + E+G IPS R+E + +
Sbjct: 33 KDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVER-KERAR 91
Query: 132 QKRGRFH---GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIP-PYDVVPSMRP 187
K +F+ G S LG+ GT + Q+ + + P + RP
Sbjct: 92 LKTVKFNAKPGVIDSKGDIPGLGDDGYGT-----KTLRGQEDLILSYEPVTRQEINYTRP 146
Query: 188 VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADIS---------LAKRSVL 237
V+++GP + D + L +F + TR D +++ +
Sbjct: 147 VIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQME 200
Query: 238 NNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPII 297
+ + IE +L + ++ + +A + +LD N +L L PI
Sbjct: 201 KDIQEHKFIEAGQYNDNL--YGTSVQSVRFVAERGKHCILDVSG-NAIKRLQVAQLYPIA 257
Query: 298 VHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLED 352
+ +K S + L + K + Q+K + + KL Q E F I+ + LED
Sbjct: 258 IFIKPRSLEPLMEMNKRLTEEQAKKTYDRAI---KLEQEFGEYFTAIVQGDTLED 309
>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
Length = 975
Score = 40.4 bits (93), Expect = 0.004
Identities = 65/308 (21%), Positives = 120/308 (38%), Gaps = 43/308 (13%)
Query: 75 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 131
+D +PS +SF D LH+ +++WW R V + E+G IPS R+E + +
Sbjct: 656 KDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVER-KERAR 714
Query: 132 QKRGRFHGGKSSGNSSSSLGEMVSGTF------------RATPTSTAKQKQKVTEHIPPY 179
K +F+ +S S + +F + T+ ++ + I Y
Sbjct: 715 LKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQETSDPERGQEDLILSY 774
Query: 180 DVVPSM-----RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADIS--- 230
+ V RPV+++GP + D + L +F + TR D
Sbjct: 775 EPVTRQEINYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDG 828
Query: 231 ------LAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINH 284
+++ + + + IE +L + ++ + +A + +LD N
Sbjct: 829 RDYHFVISREQMEKDIQEHKFIEAGQYNDNL--YGTSVQSVRFVAERGKHCILDVSG-NA 885
Query: 285 PAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVI 344
+L L PI + +K S + L + K + Q+K + + KL Q E F I
Sbjct: 886 IKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAI---KLEQEFGEYFTAI 942
Query: 345 LDENQLED 352
+ + LED
Sbjct: 943 VQGDTLED 950
>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
Length = 870
Score = 40.4 bits (93), Expect = 0.004
Identities = 65/308 (21%), Positives = 120/308 (38%), Gaps = 43/308 (13%)
Query: 75 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 131
+D +PS +SF D LH+ +++WW R V + E+G IPS R+E + +
Sbjct: 551 KDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVER-KERAR 609
Query: 132 QKRGRFHGGKSSGNSSSSLGEMVSGTF------------RATPTSTAKQKQKVTEHIPPY 179
K +F+ +S S + +F + T+ ++ + I Y
Sbjct: 610 LKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQETSDPERGQEDLILSY 669
Query: 180 DVVPSM-----RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADIS--- 230
+ V RPV+++GP + D + L +F + TR D
Sbjct: 670 EPVTRQEINYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDG 723
Query: 231 ------LAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINH 284
+++ + + + IE +L + ++ + +A + +LD N
Sbjct: 724 RDYHFVISREQMEKDIQEHKFIEAGQYNDNL--YGTSVQSVRFVAERGKHCILDVSG-NA 780
Query: 285 PAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVI 344
+L L PI + +K S + L + K + Q+K + + KL Q E F I
Sbjct: 781 IKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAI---KLEQEFGEYFTAI 837
Query: 345 LDENQLED 352
+ + LED
Sbjct: 838 VQGDTLED 845
>gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]
Length = 675
Score = 39.3 bits (90), Expect = 0.008
Identities = 70/332 (21%), Positives = 129/332 (38%), Gaps = 37/332 (11%)
Query: 50 QLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK 109
Q++ +K VK + Y + D VP +SF D LH+ + + +WW + +
Sbjct: 337 QIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW--QAYR 394
Query: 110 EGCE-----IGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTS 164
EG E G +P ++ + Q+E + K S + R
Sbjct: 395 EGDEDNQPLAGLVPG----KSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLY 450
Query: 165 TA-KQKQKVTEHIPPYDVVP-------SMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRF 216
A K E I Y+ + RP++L+GP G + +++ L + K RF
Sbjct: 451 NANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKEKDRF 507
Query: 217 DGRI-SITRVTADISLAKRSVLNNPSKRA---------IIERSNTRSSLAEVQSEIERIF 266
+ TR D +A R + S++A IE +L + I+ +
Sbjct: 508 ASAVPHTTRSRRDQEVAGRD-YHFVSRQAFEADIAAGKFIEHGEFEKNL--YGTSIDSVR 564
Query: 267 ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKS-QSKHLNV 325
++ S ++ +L T L + L P I+ + S + L+ L+ GK+ + + L
Sbjct: 565 QVINSGKICLLSLRT-QSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELRE 623
Query: 326 QLVAADKLAQCPPEMFDVILDENQLEDACEHL 357
+ ++ Q FD + + L+ A + L
Sbjct: 624 IIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
>gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens]
Length = 540
Score = 37.4 bits (85), Expect = 0.031
Identities = 36/140 (25%), Positives = 52/140 (37%), Gaps = 14/140 (10%)
Query: 58 PVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFI 117
P VK + Y D +P + F + L I + + +WW VKEG G I
Sbjct: 215 PQQVFVKCHFDYNPYNDNLIPCKEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSAGLI 274
Query: 118 PSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIP 177
PS E+KR F + NS G + S + T + + I
Sbjct: 275 PSQF--------LEEKRKAF-VRRDWDNSGPFCGTISSKKKKKMMYLTTRNAEFDRHEIQ 325
Query: 178 PYDVVPSMRP-----VVLVG 192
Y+ V M P +VL+G
Sbjct: 326 IYEEVAKMPPFQRKTLVLIG 345
>gi|186700629 calcium/calmodulin-dependent serine protein kinase
isoform 3 [Homo sapiens]
Length = 897
Score = 35.8 bits (81), Expect = 0.090
Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 63 VKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLV-KEGCEIGFIPSP 120
V+ Y A D+ +P I F D + I K +++WW G+L + G IPSP
Sbjct: 588 VRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSP 646
>gi|186700627 calcium/calmodulin-dependent serine protein kinase
isoform 2 [Homo sapiens]
Length = 898
Score = 35.8 bits (81), Expect = 0.090
Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 63 VKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLV-KEGCEIGFIPSP 120
V+ Y A D+ +P I F D + I K +++WW G+L + G IPSP
Sbjct: 594 VRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSP 652
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,340,818
Number of Sequences: 37866
Number of extensions: 805618
Number of successful extensions: 3073
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 2977
Number of HSP's gapped (non-prelim): 105
length of query: 486
length of database: 18,247,518
effective HSP length: 106
effective length of query: 380
effective length of database: 14,233,722
effective search space: 5408814360
effective search space used: 5408814360
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.