Search of human proteins with 54607064

Search of human proteins with 54607064

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|54607064 calcium channel, voltage-dependent, beta 4 subunit
isoform b [Homo sapiens]
         (520 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|54607064 calcium channel, voltage-dependent, beta 4 subunit i...  1030   0.0  
gi|54607066 calcium channel, voltage-dependent, beta 4 subunit i...   988   0.0  
gi|54607068 calcium channel, voltage-dependent, beta 4 subunit i...   936   0.0  
gi|224831262 calcium channel, voltage-dependent, beta 4 subunit ...   857   0.0  
gi|147901383 calcium channel, voltage-dependent, beta 2 subunit ...   657   0.0  
gi|147904948 calcium channel, voltage-dependent, beta 2 subunit ...   636   0.0  
gi|45359842 calcium channel, voltage-dependent, beta 2 subunit i...   636   0.0  
gi|148223541 calcium channel, voltage-dependent, beta 2 subunit ...   631   0.0  
gi|147898681 calcium channel, voltage-dependent, beta 2 subunit ...   631   0.0  
gi|40804468 calcium channel, voltage-dependent, beta 1 subunit i...   629   e-180
gi|40804472 calcium channel, voltage-dependent, beta 1 subunit i...   627   e-180
gi|148226485 calcium channel, voltage-dependent, beta 2 subunit ...   617   e-177
gi|45359834 calcium channel, voltage-dependent, beta 2 subunit i...   617   e-177
gi|148232726 calcium channel, voltage-dependent, beta 2 subunit ...   613   e-176
gi|40316928 calcium channel, voltage-dependent, beta 3 subunit [...   602   e-172
gi|40804470 calcium channel, voltage-dependent, beta 1 subunit i...   596   e-170
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi...    52   1e-06
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi...    50   4e-06
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]           49   9e-06
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi...    44   3e-04
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa...    44   3e-04
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]           44   5e-04
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]                      41   0.002
gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]                      41   0.002
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]                      40   0.004
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]                       40   0.004
gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]           39   0.009
gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens]           37   0.033
gi|186700629 calcium/calmodulin-dependent serine protein kinase ...    36   0.097
gi|186700627 calcium/calmodulin-dependent serine protein kinase ...    36   0.097

>gi|54607064 calcium channel, voltage-dependent, beta 4 subunit
           isoform b [Homo sapiens]
          Length = 520

 Score = 1030 bits (2664), Expect = 0.0
 Identities = 520/520 (100%), Positives = 520/520 (100%)

Query: 1   MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPS 60
           MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPS
Sbjct: 1   MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPS 60

Query: 61  DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISF 120
           DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISF
Sbjct: 61  DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISF 120

Query: 121 DAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNS 180
           DAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNS
Sbjct: 121 DAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNS 180

Query: 181 SSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQK 240
           SSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQK
Sbjct: 181 SSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQK 240

Query: 241 ALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIF 300
           ALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIF
Sbjct: 241 ALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIF 300

Query: 301 ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQ 360
           ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQ
Sbjct: 301 ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQ 360

Query: 361 LVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGS 420
           LVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGS
Sbjct: 361 LVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGS 420

Query: 421 TALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQH 480
           TALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQH
Sbjct: 421 TALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQH 480

Query: 481 SRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 520
           SRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL
Sbjct: 481 SRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 520


>gi|54607066 calcium channel, voltage-dependent, beta 4 subunit
           isoform c [Homo sapiens]
          Length = 502

 Score =  988 bits (2554), Expect = 0.0
 Identities = 499/499 (100%), Positives = 499/499 (100%)

Query: 22  VARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQA 81
           VARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQA
Sbjct: 4   VARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQA 63

Query: 82  AIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRL 141
           AIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRL
Sbjct: 64  AIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRL 123

Query: 142 VKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAK 201
           VKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAK
Sbjct: 124 VKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAK 183

Query: 202 QKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTA 261
           QKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTA
Sbjct: 184 QKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTA 243

Query: 262 DISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQ 321
           DISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQ
Sbjct: 244 DISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQ 303

Query: 322 LIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDE 381
           LIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDE
Sbjct: 304 LIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDE 363

Query: 382 NQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQSQRMRHS 441
           NQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQSQRMRHS
Sbjct: 364 NQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQSQRMRHS 423

Query: 442 NHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYK 501
           NHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYK
Sbjct: 424 NHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYK 483

Query: 502 PHRNRGSPGGYSHDSRHRL 520
           PHRNRGSPGGYSHDSRHRL
Sbjct: 484 PHRNRGSPGGYSHDSRHRL 502


>gi|54607068 calcium channel, voltage-dependent, beta 4 subunit
           isoform a [Homo sapiens]
          Length = 486

 Score =  936 bits (2420), Expect = 0.0
 Identities = 471/471 (100%), Positives = 471/471 (100%)

Query: 50  GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 109
           GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE
Sbjct: 16  GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75

Query: 110 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRG 169
           DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRG
Sbjct: 76  DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRG 135

Query: 170 RFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSL 229
           RFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSL
Sbjct: 136 RFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSL 195

Query: 230 KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL 289
           KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL
Sbjct: 196 KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL 255

Query: 290 AEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSR 349
           AEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSR
Sbjct: 256 AEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSR 315

Query: 350 GKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTP 409
           GKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTP
Sbjct: 316 GKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTP 375

Query: 410 MTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARK 469
           MTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARK
Sbjct: 376 MTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARK 435

Query: 470 SRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 520
           SRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL
Sbjct: 436 SRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 486


>gi|224831262 calcium channel, voltage-dependent, beta 4 subunit
           isoform d [Homo sapiens]
          Length = 458

 Score =  857 bits (2213), Expect = 0.0
 Identities = 451/520 (86%), Positives = 452/520 (86%), Gaps = 62/520 (11%)

Query: 1   MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPS 60
           MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPS
Sbjct: 1   MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPS 60

Query: 61  DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISF 120
           DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISF
Sbjct: 61  DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISF 120

Query: 121 DAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNS 180
           DAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNS
Sbjct: 121 DAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNS 180

Query: 181 SSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQK 240
           SSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQK
Sbjct: 181 SSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQK 240

Query: 241 ALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIF 300
           ALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIF
Sbjct: 241 ALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIF 300

Query: 301 ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQ 360
           ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQ
Sbjct: 301 ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQ 360

Query: 361 LVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGS 420
           LVAADKLAQCPP                           R  H+  ST            
Sbjct: 361 LVAADKLAQCPPSQ-------------------------RMRHSNHST------------ 383

Query: 421 TALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQH 480
                                    ENSPIERRSLMTSDENYHNERARKSRNRLSSSSQH
Sbjct: 384 -------------------------ENSPIERRSLMTSDENYHNERARKSRNRLSSSSQH 418

Query: 481 SRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 520
           SRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL
Sbjct: 419 SRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 458


>gi|147901383 calcium channel, voltage-dependent, beta 2 subunit
           isoform 5 [Homo sapiens]
          Length = 622

 Score =  657 bits (1695), Expect = 0.0
 Identities = 355/524 (67%), Positives = 409/524 (78%), Gaps = 34/524 (6%)

Query: 29  RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84
           R++R K SDGST    TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA  Q
Sbjct: 48  RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 106

Query: 85  LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144
           LE+AK+KPVAFAV+TNVSY  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 107 LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 166

Query: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQ 202
           GCEIGFIPSP++LEN+R+Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+AKQ
Sbjct: 167 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQ 226

Query: 203 KQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD 262
           KQK TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTAD
Sbjct: 227 KQKSTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTAD 286

Query: 263 ISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQL 322
           ISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLVVLDADTINHPAQL
Sbjct: 287 ISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQL 346

Query: 323 IKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDEN 382
            KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQCPPE+FDVILDEN
Sbjct: 347 SKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDEN 406

Query: 383 QLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQ-------- 434
           QLEDACEHL +YLEAYW+ATH  SS+   PLL R L +++L   PT  S  Q        
Sbjct: 407 QLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRT 466

Query: 435 --SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR-----NRLSSSSQHSRD 483
             S  +R ++ + E   +E     +   +S   +HN R+  SR         S +Q SRD
Sbjct: 467 DRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRD 526

Query: 484 H-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 519
             Y   +EDY   + D Y  HR+        GS      +SRHR
Sbjct: 527 SAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 570


>gi|147904948 calcium channel, voltage-dependent, beta 2 subunit
           isoform 8 [Homo sapiens]
          Length = 608

 Score =  636 bits (1641), Expect = 0.0
 Identities = 349/538 (64%), Positives = 404/538 (75%), Gaps = 48/538 (8%)

Query: 29  RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84
           R++R K SDGST    TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA  Q
Sbjct: 20  RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 78

Query: 85  LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144
           LE+AK+KPVAFAV+TNVSY  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 79  LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 138

Query: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQ 202
           GCEIGFIPSP++LEN+R+Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+  +
Sbjct: 139 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAK 198

Query: 203 KQK--------------VTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 248
                             TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH
Sbjct: 199 SADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 258

Query: 249 RFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQL 308
           RF+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQL
Sbjct: 259 RFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQL 318

Query: 309 VVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLA 368
           VVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLA
Sbjct: 319 VVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLA 378

Query: 369 QCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPT 428
           QCPPE+FDVILDENQLEDACEHL +YLEAYW+ATH  SS+   PLL R L +++L   PT
Sbjct: 379 QCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPT 438

Query: 429 AISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR--- 471
             S  Q          S  +R ++ + E   +E     +   +S   +HN R+  SR   
Sbjct: 439 LASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLS 498

Query: 472 --NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 519
                 S +Q SRD  Y   +EDY   + D Y  HR+        GS      +SRHR
Sbjct: 499 RQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 556


>gi|45359842 calcium channel, voltage-dependent, beta 2 subunit
           isoform 4 [Homo sapiens]
          Length = 636

 Score =  636 bits (1641), Expect = 0.0
 Identities = 349/538 (64%), Positives = 404/538 (75%), Gaps = 48/538 (8%)

Query: 29  RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84
           R++R K SDGST    TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA  Q
Sbjct: 48  RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 106

Query: 85  LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144
           LE+AK+KPVAFAV+TNVSY  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 107 LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 166

Query: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQ 202
           GCEIGFIPSP++LEN+R+Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+  +
Sbjct: 167 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAK 226

Query: 203 KQK--------------VTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 248
                             TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH
Sbjct: 227 SADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 286

Query: 249 RFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQL 308
           RF+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQL
Sbjct: 287 RFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQL 346

Query: 309 VVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLA 368
           VVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLA
Sbjct: 347 VVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLA 406

Query: 369 QCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPT 428
           QCPPE+FDVILDENQLEDACEHL +YLEAYW+ATH  SS+   PLL R L +++L   PT
Sbjct: 407 QCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPT 466

Query: 429 AISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR--- 471
             S  Q          S  +R ++ + E   +E     +   +S   +HN R+  SR   
Sbjct: 467 LASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLS 526

Query: 472 --NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 519
                 S +Q SRD  Y   +EDY   + D Y  HR+        GS      +SRHR
Sbjct: 527 RQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 584


>gi|148223541 calcium channel, voltage-dependent, beta 2 subunit
           isoform 6 [Homo sapiens]
          Length = 632

 Score =  631 bits (1628), Expect = 0.0
 Identities = 353/562 (62%), Positives = 409/562 (72%), Gaps = 72/562 (12%)

Query: 29  RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84
           R++R K SDGST    TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA  Q
Sbjct: 20  RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 78

Query: 85  LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144
           LE+AK+KPVAFAV+TNVSY  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 79  LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 138

Query: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA-- 200
           GCEIGFIPSP++LEN+R+Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+A  
Sbjct: 139 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAID 198

Query: 201 --------------------------------KQKQ----KVTEHIPPYDVVPSMRPVVL 224
                                           K+K+    K TEH PPYDVVPSMRPVVL
Sbjct: 199 IDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVL 258

Query: 225 VGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSN 284
           VGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSK AIIERSN
Sbjct: 259 VGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSN 318

Query: 285 TRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQR 344
           TRSSLAEVQSEIERIFELAR+LQLVVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQR
Sbjct: 319 TRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQR 378

Query: 345 LIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHT 404
           LIKSRGKSQ+KHLNVQ+VAADKLAQCPPE+FDVILDENQLEDACEHL +YLEAYW+ATH 
Sbjct: 379 LIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHP 438

Query: 405 TSSTPMTPLLGRNLGSTALSPYPTAISGLQ----------SQRMRHSNHSTENSPIE--- 451
            SS+   PLL R L +++L   PT  S  Q          S  +R ++ + E   +E   
Sbjct: 439 PSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVK 498

Query: 452 -RRSLMTSDENYHNERARKSR-----NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHR 504
             +   +S   +HN R+  SR         S +Q SRD  Y   +EDY   + D Y  HR
Sbjct: 499 KSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHR 558

Query: 505 N-------RGSPGGYSHDSRHR 519
           +        GS      +SRHR
Sbjct: 559 DHNHRDETHGSSDHRHRESRHR 580


>gi|147898681 calcium channel, voltage-dependent, beta 2 subunit
           isoform 2 [Homo sapiens]
          Length = 660

 Score =  631 bits (1628), Expect = 0.0
 Identities = 353/562 (62%), Positives = 409/562 (72%), Gaps = 72/562 (12%)

Query: 29  RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84
           R++R K SDGST    TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA  Q
Sbjct: 48  RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 106

Query: 85  LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144
           LE+AK+KPVAFAV+TNVSY  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 107 LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 166

Query: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA-- 200
           GCEIGFIPSP++LEN+R+Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+A  
Sbjct: 167 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAID 226

Query: 201 --------------------------------KQKQ----KVTEHIPPYDVVPSMRPVVL 224
                                           K+K+    K TEH PPYDVVPSMRPVVL
Sbjct: 227 IDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVL 286

Query: 225 VGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSN 284
           VGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSK AIIERSN
Sbjct: 287 VGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSN 346

Query: 285 TRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQR 344
           TRSSLAEVQSEIERIFELAR+LQLVVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQR
Sbjct: 347 TRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQR 406

Query: 345 LIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHT 404
           LIKSRGKSQ+KHLNVQ+VAADKLAQCPPE+FDVILDENQLEDACEHL +YLEAYW+ATH 
Sbjct: 407 LIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHP 466

Query: 405 TSSTPMTPLLGRNLGSTALSPYPTAISGLQ----------SQRMRHSNHSTENSPIE--- 451
            SS+   PLL R L +++L   PT  S  Q          S  +R ++ + E   +E   
Sbjct: 467 PSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVK 526

Query: 452 -RRSLMTSDENYHNERARKSR-----NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHR 504
             +   +S   +HN R+  SR         S +Q SRD  Y   +EDY   + D Y  HR
Sbjct: 527 KSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHR 586

Query: 505 N-------RGSPGGYSHDSRHR 519
           +        GS      +SRHR
Sbjct: 587 DHNHRDETHGSSDHRHRESRHR 608


>gi|40804468 calcium channel, voltage-dependent, beta 1 subunit
           isoform 1 [Homo sapiens]
          Length = 598

 Score =  629 bits (1621), Expect = e-180
 Identities = 322/463 (69%), Positives = 376/463 (81%), Gaps = 16/463 (3%)

Query: 8   KNGTADGPHSPTSQVARGT---------TTRRSRLKRSDGST----TSTSFILRQGSADS 54
           K   + GP+ P+ ++             + R+ R KRSDGST    TS SF+ RQGSA+S
Sbjct: 4   KTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFV-RQGSAES 62

Query: 55  YTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVP 114
           YTSRPSDSDVSLEEDREA+R+E E+QA  QLE+AK+KPVAFAV+TNV Y  +  ++VPV 
Sbjct: 63  YTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQ 122

Query: 115 STAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQK--RGRFH 172
             AI+F+ KDFLHIKEKYNNDWWIGRLVKEGCE+GFIPSP++L+++R+ QEQK  + R  
Sbjct: 123 GVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLG 182

Query: 173 GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGY 232
             KS  NSSSSLG++V+GT R TP ++AKQKQK TEH+PPYDVVPSMRP++LVGPSLKGY
Sbjct: 183 SSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGY 242

Query: 233 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEV 292
           EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSK  IIERSNTRSSLAEV
Sbjct: 243 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEV 302

Query: 293 QSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKS 352
           QSEIERIFELAR+LQLV LDADTINHPAQL KTSLAPIIV++K++SPKVLQRLIKSRGKS
Sbjct: 303 QSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKS 362

Query: 353 QSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTP 412
           QSKHLNVQ+ A++KLAQCPPEMFD+ILDENQLEDACEHL EYLEAYW+ATH  SSTP  P
Sbjct: 363 QSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNP 422

Query: 413 LLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSL 455
           LL R + + AL+  P  +S LQ   +   +   E +  E  S+
Sbjct: 423 LLNRTMATAALAASPAPVSNLQGPYLASGDQPLERATGEHASM 465


>gi|40804472 calcium channel, voltage-dependent, beta 1 subunit
           isoform 3 [Homo sapiens]
          Length = 478

 Score =  627 bits (1617), Expect = e-180
 Identities = 320/444 (72%), Positives = 370/444 (83%), Gaps = 16/444 (3%)

Query: 8   KNGTADGPHSPTSQVARGT---------TTRRSRLKRSDGST----TSTSFILRQGSADS 54
           K   + GP+ P+ ++             + R+ R KRSDGST    TS SF+ RQGSA+S
Sbjct: 4   KTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFV-RQGSAES 62

Query: 55  YTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVP 114
           YTSRPSDSDVSLEEDREA+R+E E+QA  QLE+AK+KPVAFAV+TNV Y  +  ++VPV 
Sbjct: 63  YTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQ 122

Query: 115 STAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQK--RGRFH 172
             AI+F+ KDFLHIKEKYNNDWWIGRLVKEGCE+GFIPSP++L+++R+ QEQK  + R  
Sbjct: 123 GVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLG 182

Query: 173 GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGY 232
             KS  NSSSSLG++V+GT R TP ++AKQKQK TEH+PPYDVVPSMRP++LVGPSLKGY
Sbjct: 183 SSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGY 242

Query: 233 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEV 292
           EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSK  IIERSNTRSSLAEV
Sbjct: 243 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEV 302

Query: 293 QSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKS 352
           QSEIERIFELAR+LQLV LDADTINHPAQL KTSLAPIIV++K++SPKVLQRLIKSRGKS
Sbjct: 303 QSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKS 362

Query: 353 QSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTP 412
           QSKHLNVQ+ A++KLAQCPPEMFD+ILDENQLEDACEHL EYLEAYW+ATH  SSTP  P
Sbjct: 363 QSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNP 422

Query: 413 LLGRNLGSTALSPYPTAISGLQSQ 436
           LL R + + AL+  P  +S LQ Q
Sbjct: 423 LLNRTMATAALAASPAPVSNLQVQ 446


>gi|148226485 calcium channel, voltage-dependent, beta 2 subunit
           isoform 3 [Homo sapiens]
          Length = 606

 Score =  617 bits (1592), Expect = e-177
 Identities = 341/544 (62%), Positives = 396/544 (72%), Gaps = 67/544 (12%)

Query: 43  TSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVS 102
           T +I+  GSADSYTSRPSDSDVSLEEDREA+R+E E+QA  QLE+AK+KPVAFAV+TNVS
Sbjct: 11  TKYIIPGGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVS 70

Query: 103 YCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRI 162
           Y  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+
Sbjct: 71  YSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRL 130

Query: 163 QQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA-------------------- 200
           Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+A                    
Sbjct: 131 QHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHR 190

Query: 201 --------------KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL 242
                         K+K+    K TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL
Sbjct: 191 SPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL 250

Query: 243 FDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFEL 302
           FDFLKHRF+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFEL
Sbjct: 251 FDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFEL 310

Query: 303 ARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLV 362
           AR+LQLVVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+V
Sbjct: 311 ARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMV 370

Query: 363 AADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTA 422
           AADKLAQCPPE+FDVILDENQLEDACEHL +YLEAYW+ATH  SS+   PLL R L +++
Sbjct: 371 AADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSS 430

Query: 423 LSPYPTAISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERAR 468
           L   PT  S  Q          S  +R ++ + E   +E     +   +S   +HN R+ 
Sbjct: 431 LPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSG 490

Query: 469 KSR-----NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHD 515
            SR         S +Q SRD  Y   +EDY   + D Y  HR+        GS      +
Sbjct: 491 TSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRE 550

Query: 516 SRHR 519
           SRHR
Sbjct: 551 SRHR 554


>gi|45359834 calcium channel, voltage-dependent, beta 2 subunit
           isoform 7 [Homo sapiens]
          Length = 612

 Score =  617 bits (1591), Expect = e-177
 Identities = 345/554 (62%), Positives = 399/554 (72%), Gaps = 69/554 (12%)

Query: 33  LKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKP 92
           LKR+ G     S I   GSADSYTSRPSDSDVSLEEDREA+R+E E+QA  QLE+AK+KP
Sbjct: 9   LKRAKGGRLKNSDIC--GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKP 66

Query: 93  VAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIP 152
           VAFAV+TNVSY  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIP
Sbjct: 67  VAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIP 126

Query: 153 SPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA---------- 200
           SP++LEN+R+Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+A          
Sbjct: 127 SPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDA 186

Query: 201 ------------------------KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGY 232
                                   K+K+    K TEH PPYDVVPSMRPVVLVGPSLKGY
Sbjct: 187 EENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGY 246

Query: 233 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEV 292
           EVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEV
Sbjct: 247 EVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEV 306

Query: 293 QSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKS 352
           QSEIERIFELAR+LQLVVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKS
Sbjct: 307 QSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKS 366

Query: 353 QSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTP 412
           Q+KHLNVQ+VAADKLAQCPPE+FDVILDENQLEDACEHL +YLEAYW+ATH  SS+   P
Sbjct: 367 QAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNP 426

Query: 413 LLGRNLGSTALSPYPTAISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTS 458
           LL R L +++L   PT  S  Q          S  +R ++ + E   +E     +   +S
Sbjct: 427 LLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSS 486

Query: 459 DENYHNERARKSR-----NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN------- 505
              +HN R+  SR         S +Q SRD  Y   +EDY   + D Y  HR+       
Sbjct: 487 SAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDET 546

Query: 506 RGSPGGYSHDSRHR 519
            GS      +SRHR
Sbjct: 547 HGSSDHRHRESRHR 560


>gi|148232726 calcium channel, voltage-dependent, beta 2 subunit
           isoform 1 [Homo sapiens]
          Length = 605

 Score =  613 bits (1582), Expect = e-176
 Identities = 339/537 (63%), Positives = 392/537 (72%), Gaps = 67/537 (12%)

Query: 50  GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 109
           GSADSYTSRPSDSDVSLEEDREA+R+E E+QA  QLE+AK+KPVAFAV+TNVSY  A ++
Sbjct: 17  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 76

Query: 110 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQ--K 167
           DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+Q EQ  K
Sbjct: 77  DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 136

Query: 168 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA--------------------------- 200
           +G+F+  KS GNSSSSLG++V  + ++TP S+A                           
Sbjct: 137 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 196

Query: 201 -------KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 249
                  K+K+    K TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 197 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 256

Query: 250 FDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLV 309
           F+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLV
Sbjct: 257 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 316

Query: 310 VLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQ 369
           VLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQ
Sbjct: 317 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 376

Query: 370 CPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTA 429
           CPPE+FDVILDENQLEDACEHL +YLEAYW+ATH  SS+   PLL R L +++L   PT 
Sbjct: 377 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 436

Query: 430 ISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR---- 471
            S  Q          S  +R ++ + E   +E     +   +S   +HN R+  SR    
Sbjct: 437 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 496

Query: 472 -NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 519
                S +Q SRD  Y   +EDY   + D Y  HR+        GS      +SRHR
Sbjct: 497 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 553


>gi|40316928 calcium channel, voltage-dependent, beta 3 subunit
           [Homo sapiens]
          Length = 484

 Score =  602 bits (1551), Expect = e-172
 Identities = 331/474 (69%), Positives = 368/474 (77%), Gaps = 33/474 (6%)

Query: 50  GSADSYTSRPS-DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALD 108
           GSADSYTSRPS DSDVSLEEDRE+ R+E E QA  QLERAK KPVAFAV+TNVSYCG LD
Sbjct: 16  GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75

Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKR 168
           E+ PV  + ++F+AKDFLHIKEKY+NDWWIGRLVKEG +I FIPSP RLE+IR++QEQK 
Sbjct: 76  EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135

Query: 169 GRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPS 228
            R      SGN SS L ++  G  R+ P S AKQKQK  EH+PPYDVVPSMRPVVLVGPS
Sbjct: 136 RR------SGNPSS-LSDI--GNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPVVLVGPS 186

Query: 229 LKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS 288
           LKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD+SLAKRSVLNNP KR IIERS+ RSS
Sbjct: 187 LKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSS 246

Query: 289 LAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKS 348
           +AEVQSEIERIFELA+SLQLVVLDADTINHPAQL KTSLAPIIV VKVSSPKVLQRLI+S
Sbjct: 247 IAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRS 306

Query: 349 RGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSST 408
           RGKSQ KHL VQ++A DKL QCPPE FDVILDENQLEDACEHL EYLE YWRATH  +  
Sbjct: 307 RGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPAPG 366

Query: 409 PMTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERAR 468
           P   LLG           P+AI GLQ+Q++       E+SP+ER SLM SD     E + 
Sbjct: 367 P--GLLGP----------PSAIPGLQNQQLL-GERGEEHSPLERDSLMPSD-----EASE 408

Query: 469 KSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNR--GSPGGYSHDSRHRL 520
            SR   + SSQ S  H   +EEDY D+YQD Y+PHR    G P    HD + RL
Sbjct: 409 SSRQAWTGSSQRSSRH---LEEDYADAYQDLYQPHRQHTSGLPSANGHDPQDRL 459


>gi|40804470 calcium channel, voltage-dependent, beta 1 subunit
           isoform 2 [Homo sapiens]
          Length = 523

 Score =  596 bits (1537), Expect = e-170
 Identities = 315/489 (64%), Positives = 366/489 (74%), Gaps = 61/489 (12%)

Query: 8   KNGTADGPHSPTSQVARGT---------TTRRSRLKRSDGST----TSTSFILRQGSADS 54
           K   + GP+ P+ ++             + R+ R KRSDGST    TS SF+ RQGSA+S
Sbjct: 4   KTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFV-RQGSAES 62

Query: 55  YTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVP 114
           YTSRPSDSDVSLEEDREA+R+E E+QA  QLE+AK+KPVAFAV+TNV Y  +  ++VPV 
Sbjct: 63  YTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQ 122

Query: 115 STAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQK--RGRFH 172
             AI+F+ KDFLHIKEKYNNDWWIGRLVKEGCE+GFIPSP++L+++R+ QEQK  + R  
Sbjct: 123 GVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLG 182

Query: 173 GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQ---------------------------- 204
             KS  NSSSSLG++V+GT R TP ++  +                              
Sbjct: 183 SSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGEQSGSAKTS 242

Query: 205 -----------------KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLK 247
                            K TEH+PPYDVVPSMRP++LVGPSLKGYEVTDMMQKALFDFLK
Sbjct: 243 VSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLK 302

Query: 248 HRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQ 307
           HRFDGRISITRVTADISLAKRSVLNNPSK  IIERSNTRSSLAEVQSEIERIFELAR+LQ
Sbjct: 303 HRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQ 362

Query: 308 LVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKL 367
           LV LDADTINHPAQL KTSLAPIIV++K++SPKVLQRLIKSRGKSQSKHLNVQ+ A++KL
Sbjct: 363 LVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKL 422

Query: 368 AQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYP 427
           AQCPPEMFD+ILDENQLEDACEHL EYLEAYW+ATH  SSTP  PLL R + + AL+  P
Sbjct: 423 AQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASP 482

Query: 428 TAISGLQSQ 436
             +S LQ Q
Sbjct: 483 APVSNLQVQ 491


>gi|119943106 synapse-associated protein 102 isoform a [Homo
           sapiens]
          Length = 817

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 67/301 (22%), Positives = 121/301 (40%), Gaps = 29/301 (9%)

Query: 110 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQEQ 166
           D  +PS  +SF   D LH+    +++WW  RLV    E  +IG IPS  R+E  + +   
Sbjct: 517 DSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEK-KERARL 575

Query: 167 KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIP-PYDVVPSMRPVVLV 225
           K  +FH       S+     +    + A   +   Q+  +  + P     +   RPV+++
Sbjct: 576 KTVKFHARTGMIESNRDFPGLSDDYYGA--KNLKGQEDAILSYEPVTRQEIHYARPVIIL 633

Query: 226 GPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTAD---------ISLAKRSVLNNPS 275
           GP      + D +   L     H+F   +   TR   D           +++  +  +  
Sbjct: 634 GP------MKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQ 687

Query: 276 KRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVK 335
               IE      +L    + I+ +  +A   +  +LD    N   +L +  L PI + +K
Sbjct: 688 DNKFIEAGQFNDNL--YGTSIQSVRAVAERGKHCILDVSG-NAIKRLQQAQLYPIAIFIK 744

Query: 336 VSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYL 395
              PK ++ L++   +   +  N     A KL Q   E F  I+  + LE+    + + +
Sbjct: 745 ---PKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQII 801

Query: 396 E 396
           E
Sbjct: 802 E 802


>gi|119943108 synapse-associated protein 102 isoform b [Homo
           sapiens]
          Length = 512

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 72/330 (21%), Positives = 130/330 (39%), Gaps = 55/330 (16%)

Query: 110 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLE-------- 158
           D  +PS  +SF   D LH+    +++WW  RLV    E  +IG IPS  R+E        
Sbjct: 180 DSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLK 239

Query: 159 -------------NIRIQQEQKRG-------RFHGGKSSGNSSSSLGEM-VSGTFRATPT 197
                        N  I+ ++K+         F+  K +    SS+ E  V+     + +
Sbjct: 240 TVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSES 299

Query: 198 STAKQKQKVTEHIP-PYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-S 255
           S+  Q+  +  + P     +   RPV+++GP      + D +   L     H+F   +  
Sbjct: 300 SSKGQEDAILSYEPVTRQEIHYARPVIILGP------MKDRVNDDLISEFPHKFGSCVPH 353

Query: 256 ITRVTAD---------ISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSL 306
            TR   D           +++  +  +      IE      +L    + I+ +  +A   
Sbjct: 354 TTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNL--YGTSIQSVRAVAERG 411

Query: 307 QLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADK 366
           +  +LD    N   +L +  L PI + +K   PK ++ L++   +   +  N     A K
Sbjct: 412 KHCILDVSG-NAIKRLQQAQLYPIAIFIK---PKSIEALMEMNRRQTYEQANKIYDKAMK 467

Query: 367 LAQCPPEMFDVILDENQLEDACEHLGEYLE 396
           L Q   E F  I+  + LE+    + + +E
Sbjct: 468 LEQEFGEYFTAIVQGDSLEEIYNKIKQIIE 497


>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
          Length = 904

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 63/307 (20%), Positives = 122/307 (39%), Gaps = 32/307 (10%)

Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 165
           +D  +PS  ++F   D LH+    +++WW  R V    E  E+G IPS  R+E  + +  
Sbjct: 596 KDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEK-KERAR 654

Query: 166 QKRGRFHG-GKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSM----- 219
            K  +F+   +  G     +G        +  + +    +   E++  Y+ V        
Sbjct: 655 LKTVKFNSKTRDKGEIPDDMGSKGLKHVTSNASDSESSYRGQEEYVLSYEPVNQQEVNYT 714

Query: 220 RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADISL---------AKRS 269
           RPV+++GP      + D +   L      +F   +   TR   D  +         ++  
Sbjct: 715 RPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQ 768

Query: 270 VLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAP 329
           +  +  +   IE     + L    + ++ + E+A   +  +LD    N   +L    L P
Sbjct: 769 MEKDIQEHKFIEAGQYNNHL--YGTSVQSVREVAEKGKHCILDVSG-NAIKRLQIAQLYP 825

Query: 330 IIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACE 389
           I + +K   PK ++ +++   +   +        A KL Q   E F  I+  + LED   
Sbjct: 826 ISIFIK---PKSMENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYN 882

Query: 390 HLGEYLE 396
            + + +E
Sbjct: 883 QVKQIIE 889


>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
           sapiens]
          Length = 767

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 70/301 (23%), Positives = 118/301 (39%), Gaps = 59/301 (19%)

Query: 115 STAISFDAKDFLHIKEKYNNDWWIGRLV---KEGCEIGFIPSPLRLENIRIQQEQKRGRF 171
           S A+SF   D LH+ +  + +WW  R V    E  +IGFIPS  R+E    ++E  R + 
Sbjct: 492 SQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVE----RREWSRLK- 546

Query: 172 HGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKG 231
              K  G+SS S G   S     T T                  V   RP++++GP+ K 
Sbjct: 547 --AKDWGSSSGSQGREDSVLSYETVTQME---------------VHYARPIIILGPT-KD 588

Query: 232 YEVTDMMQKALFDF-----------LKHRFDGR-----ISITRVTADISLAKRSVLNNPS 275
               D++ +    F            ++  DGR      S  ++  DI   K        
Sbjct: 589 RANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHK-------- 640

Query: 276 KRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVK 335
               IE     S L    + ++ + E+A   +  +LD  + N   +L    L PI + ++
Sbjct: 641 ---FIEAGQYNSHL--YGTSVQSVREVAEQGKHCILDV-SANAVRRLQAAHLHPIAIFIR 694

Query: 336 VSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYL 395
              P+ L+ +++   +   +        A KL Q   E F  I++ +  E+    +   +
Sbjct: 695 ---PRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVI 751

Query: 396 E 396
           E
Sbjct: 752 E 752


>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
           sapiens]
          Length = 721

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 70/301 (23%), Positives = 118/301 (39%), Gaps = 59/301 (19%)

Query: 115 STAISFDAKDFLHIKEKYNNDWWIGRLV---KEGCEIGFIPSPLRLENIRIQQEQKRGRF 171
           S A+SF   D LH+ +  + +WW  R V    E  +IGFIPS  R+E    ++E  R + 
Sbjct: 446 SQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVE----RREWSRLK- 500

Query: 172 HGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKG 231
              K  G+SS S G   S     T T                  V   RP++++GP+ K 
Sbjct: 501 --AKDWGSSSGSQGREDSVLSYETVTQME---------------VHYARPIIILGPT-KD 542

Query: 232 YEVTDMMQKALFDF-----------LKHRFDGR-----ISITRVTADISLAKRSVLNNPS 275
               D++ +    F            ++  DGR      S  ++  DI   K        
Sbjct: 543 RANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHK-------- 594

Query: 276 KRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVK 335
               IE     S L    + ++ + E+A   +  +LD  + N   +L    L PI + ++
Sbjct: 595 ---FIEAGQYNSHL--YGTSVQSVREVAEQGKHCILDV-SANAVRRLQAAHLHPIAIFIR 648

Query: 336 VSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYL 395
              P+ L+ +++   +   +        A KL Q   E F  I++ +  E+    +   +
Sbjct: 649 ---PRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVI 705

Query: 396 E 396
           E
Sbjct: 706 E 706


>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
          Length = 926

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 67/328 (20%), Positives = 127/328 (38%), Gaps = 52/328 (15%)

Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRL---ENIRI 162
           +D  +PS  ++F   D LH+    +++WW  R V    E  E+G IPS  R+   E  R+
Sbjct: 596 KDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARL 655

Query: 163 Q------QEQKRGRFHGGKSSGN-----------------SSSSLGEMVSGTFRATPTST 199
           +      + + +G+    K   N                  +S   + V+     + +S 
Sbjct: 656 KTVKFNSKTRDKGQSFNDKRKKNLFSRKFPFYKNKDQSEQETSDADQHVTSNASDSESSY 715

Query: 200 AKQKQKVTEHIP-PYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SIT 257
             Q++ V  + P     V   RPV+++GP      + D +   L      +F   +   T
Sbjct: 716 RGQEEYVLSYEPVNQQEVNYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTT 769

Query: 258 RVTADISL---------AKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQL 308
           R   D  +         ++  +  +  +   IE     + L    + ++ + E+A   + 
Sbjct: 770 RPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHL--YGTSVQSVREVAEKGKH 827

Query: 309 VVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLA 368
            +LD    N   +L    L PI + +K   PK ++ +++   +   +        A KL 
Sbjct: 828 CILDVSG-NAIKRLQIAQLYPISIFIK---PKSMENIMEMNKRLTEEQARKTFERAMKLE 883

Query: 369 QCPPEMFDVILDENQLEDACEHLGEYLE 396
           Q   E F  I+  + LED    + + +E
Sbjct: 884 QEFTEHFTAIVQGDTLEDIYNQVKQIIE 911


>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
          Length = 749

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 66/295 (22%), Positives = 118/295 (40%), Gaps = 35/295 (11%)

Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 165
           +D  +PS  +SF   D LH+    +++WW  R V    +  E+G IPS  R+E  + +  
Sbjct: 448 KDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVER-KERAR 506

Query: 166 QKRGRFH---GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIP-PYDVVPSMRP 221
            K  +F+   G   S      LG+   GT      +   Q+  +  + P     +   RP
Sbjct: 507 LKTVKFNAKPGVIDSKGDIPGLGDDGYGT-----KTLRGQEDLILSYEPVTRQEINYTRP 561

Query: 222 VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADIS---------LAKRSVL 271
           V+++GP      + D +   L      +F   +   TR   D           +++  + 
Sbjct: 562 VIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQME 615

Query: 272 NNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPII 331
            +  +   IE      +L    + ++ +  +A   +  +LD    N   +L    L PI 
Sbjct: 616 KDIQEHKFIEAGQYNDNL--YGTSVQSVRFVAERGKHCILDVSG-NAIKRLQVAQLYPIA 672

Query: 332 VHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLED 386
           + +K  S + L  + K   + Q+K    + +   KL Q   E F  I+  + LED
Sbjct: 673 IFIKPRSLEPLMEMNKRLTEEQAKKTYDRAI---KLEQEFGEYFTAIVQGDTLED 724


>gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]
          Length = 334

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 66/295 (22%), Positives = 118/295 (40%), Gaps = 35/295 (11%)

Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 165
           +D  +PS  +SF   D LH+    +++WW  R V    +  E+G IPS  R+E  + +  
Sbjct: 33  KDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVER-KERAR 91

Query: 166 QKRGRFH---GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIP-PYDVVPSMRP 221
            K  +F+   G   S      LG+   GT      +   Q+  +  + P     +   RP
Sbjct: 92  LKTVKFNAKPGVIDSKGDIPGLGDDGYGT-----KTLRGQEDLILSYEPVTRQEINYTRP 146

Query: 222 VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADIS---------LAKRSVL 271
           V+++GP      + D +   L      +F   +   TR   D           +++  + 
Sbjct: 147 VIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQME 200

Query: 272 NNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPII 331
            +  +   IE      +L    + ++ +  +A   +  +LD    N   +L    L PI 
Sbjct: 201 KDIQEHKFIEAGQYNDNL--YGTSVQSVRFVAERGKHCILDVSG-NAIKRLQVAQLYPIA 257

Query: 332 VHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLED 386
           + +K  S + L  + K   + Q+K    + +   KL Q   E F  I+  + LED
Sbjct: 258 IFIKPRSLEPLMEMNKRLTEEQAKKTYDRAI---KLEQEFGEYFTAIVQGDTLED 309


>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
          Length = 975

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 65/308 (21%), Positives = 120/308 (38%), Gaps = 43/308 (13%)

Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 165
           +D  +PS  +SF   D LH+    +++WW  R V    +  E+G IPS  R+E  + +  
Sbjct: 656 KDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVER-KERAR 714

Query: 166 QKRGRFHGGKSSGNSSSSLGEMVSGTF------------RATPTSTAKQKQKVTEHIPPY 213
            K  +F+      +S  S  +    +F              +   T+  ++   + I  Y
Sbjct: 715 LKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQETSDPERGQEDLILSY 774

Query: 214 DVVPSM-----RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADIS--- 264
           + V        RPV+++GP      + D +   L      +F   +   TR   D     
Sbjct: 775 EPVTRQEINYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDG 828

Query: 265 ------LAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINH 318
                 +++  +  +  +   IE      +L    + ++ +  +A   +  +LD    N 
Sbjct: 829 RDYHFVISREQMEKDIQEHKFIEAGQYNDNL--YGTSVQSVRFVAERGKHCILDVSG-NA 885

Query: 319 PAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVI 378
             +L    L PI + +K  S + L  + K   + Q+K    + +   KL Q   E F  I
Sbjct: 886 IKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAI---KLEQEFGEYFTAI 942

Query: 379 LDENQLED 386
           +  + LED
Sbjct: 943 VQGDTLED 950


>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
          Length = 870

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 65/308 (21%), Positives = 120/308 (38%), Gaps = 43/308 (13%)

Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 165
           +D  +PS  +SF   D LH+    +++WW  R V    +  E+G IPS  R+E  + +  
Sbjct: 551 KDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVER-KERAR 609

Query: 166 QKRGRFHGGKSSGNSSSSLGEMVSGTF------------RATPTSTAKQKQKVTEHIPPY 213
            K  +F+      +S  S  +    +F              +   T+  ++   + I  Y
Sbjct: 610 LKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQETSDPERGQEDLILSY 669

Query: 214 DVVPSM-----RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADIS--- 264
           + V        RPV+++GP      + D +   L      +F   +   TR   D     
Sbjct: 670 EPVTRQEINYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDG 723

Query: 265 ------LAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINH 318
                 +++  +  +  +   IE      +L    + ++ +  +A   +  +LD    N 
Sbjct: 724 RDYHFVISREQMEKDIQEHKFIEAGQYNDNL--YGTSVQSVRFVAERGKHCILDVSG-NA 780

Query: 319 PAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVI 378
             +L    L PI + +K  S + L  + K   + Q+K    + +   KL Q   E F  I
Sbjct: 781 IKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAI---KLEQEFGEYFTAI 837

Query: 379 LDENQLED 386
           +  + LED
Sbjct: 838 VQGDTLED 845


>gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]
          Length = 675

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 70/332 (21%), Positives = 129/332 (38%), Gaps = 37/332 (11%)

Query: 84  QLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK 143
           Q++   +K     VK +  Y  + D  VP     +SF   D LH+  + + +WW  +  +
Sbjct: 337 QIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW--QAYR 394

Query: 144 EGCE-----IGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTS 198
           EG E      G +P     ++ + Q+E  +      K    S        +   R     
Sbjct: 395 EGDEDNQPLAGLVPG----KSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLY 450

Query: 199 TA-KQKQKVTEHIPPYDVVP-------SMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRF 250
            A K      E I  Y+ +          RP++L+GP   G    + +++ L +  K RF
Sbjct: 451 NANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKEKDRF 507

Query: 251 DGRI-SITRVTADISLAKRSVLNNPSKRA---------IIERSNTRSSLAEVQSEIERIF 300
              +   TR   D  +A R   +  S++A          IE      +L    + I+ + 
Sbjct: 508 ASAVPHTTRSRRDQEVAGRD-YHFVSRQAFEADIAAGKFIEHGEFEKNL--YGTSIDSVR 564

Query: 301 ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKS-QSKHLNV 359
           ++  S ++ +L   T      L  + L P I+ +   S + L+ L+   GK+ + + L  
Sbjct: 565 QVINSGKICLLSLRT-QSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELRE 623

Query: 360 QLVAADKLAQCPPEMFDVILDENQLEDACEHL 391
            +    ++ Q     FD  +  + L+ A + L
Sbjct: 624 IIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655


>gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens]
          Length = 540

 Score = 37.4 bits (85), Expect = 0.033
 Identities = 36/140 (25%), Positives = 52/140 (37%), Gaps = 14/140 (10%)

Query: 92  PVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFI 151
           P    VK +  Y    D  +P     + F   + L I  + + +WW    VKEG   G I
Sbjct: 215 PQQVFVKCHFDYNPYNDNLIPCKEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSAGLI 274

Query: 152 PSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIP 211
           PS           E+KR  F   +   NS    G + S   +     T +  +     I 
Sbjct: 275 PSQF--------LEEKRKAF-VRRDWDNSGPFCGTISSKKKKKMMYLTTRNAEFDRHEIQ 325

Query: 212 PYDVVPSMRP-----VVLVG 226
            Y+ V  M P     +VL+G
Sbjct: 326 IYEEVAKMPPFQRKTLVLIG 345


>gi|186700629 calcium/calmodulin-dependent serine protein kinase
           isoform 3 [Homo sapiens]
          Length = 897

 Score = 35.8 bits (81), Expect = 0.097
 Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 97  VKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLV-KEGCEIGFIPSP 154
           V+    Y  A D+ +P     I F   D + I  K +++WW G+L   +    G IPSP
Sbjct: 588 VRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSP 646


>gi|186700627 calcium/calmodulin-dependent serine protein kinase
           isoform 2 [Homo sapiens]
          Length = 898

 Score = 35.8 bits (81), Expect = 0.097
 Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 97  VKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLV-KEGCEIGFIPSP 154
           V+    Y  A D+ +P     I F   D + I  K +++WW G+L   +    G IPSP
Sbjct: 594 VRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSP 652


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.128    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,537,025
Number of Sequences: 37866
Number of extensions: 855867
Number of successful extensions: 3376
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 3274
Number of HSP's gapped (non-prelim): 116
length of query: 520
length of database: 18,247,518
effective HSP length: 107
effective length of query: 413
effective length of database: 14,195,856
effective search space: 5862888528
effective search space used: 5862888528
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.