BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|54144625 numb homolog isoform 1 [Homo sapiens] (651 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|54144625 numb homolog isoform 1 [Homo sapiens] 1323 0.0 gi|20070356 numb homolog isoform 3 [Homo sapiens] 1291 0.0 gi|54144627 numb homolog isoform 2 [Homo sapiens] 1202 0.0 gi|54144629 numb homolog isoform 4 [Homo sapiens] 1170 0.0 gi|10863899 numb homolog (Drosophila)-like [Homo sapiens] 566 e-161 gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Hom... 84 5e-16 gi|132626790 low density lipoprotein receptor adaptor protein 1 ... 74 3e-13 gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 57 5e-08 gi|50511947 cajalin 2 isoform b [Homo sapiens] 57 7e-08 gi|50511945 cajalin 2 isoform a [Homo sapiens] 57 7e-08 gi|10047134 cajalin 2 isoform c [Homo sapiens] 57 7e-08 gi|33350928 disabled homolog 1 [Homo sapiens] 55 2e-07 gi|140161500 ankyrin repeat and sterile alpha motif domain conta... 54 3e-07 gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ... 51 4e-06 gi|31317301 nitric oxide synthase 1 (neuronal) adaptor protein i... 50 7e-06 gi|26051278 nuclear pore membrane protein 121 [Homo sapiens] 50 7e-06 gi|19111150 angiomotin isoform 2 [Homo sapiens] 49 1e-05 gi|166064029 angiomotin isoform 1 [Homo sapiens] 49 1e-05 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 48 2e-05 gi|148491082 disabled homolog 2 [Homo sapiens] 47 4e-05 gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] 47 6e-05 gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 46 9e-05 gi|91208420 bassoon protein [Homo sapiens] 45 2e-04 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 44 5e-04 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 44 5e-04 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 44 5e-04 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 44 5e-04 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 44 5e-04 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 44 5e-04 gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 44 5e-04 >gi|54144625 numb homolog isoform 1 [Homo sapiens] Length = 651 Score = 1323 bits (3425), Expect = 0.0 Identities = 651/651 (100%), Positives = 651/651 (100%) Query: 1 MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60 MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED Sbjct: 1 MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60 Query: 61 AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 120 AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD Sbjct: 61 AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 120 Query: 121 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 180 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA Sbjct: 121 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 180 Query: 181 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 240 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS Sbjct: 181 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 240 Query: 241 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 300 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE Sbjct: 241 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 300 Query: 301 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 360 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ Sbjct: 301 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 360 Query: 361 SPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQS 420 SPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQS Sbjct: 361 SPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQS 420 Query: 421 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS 480 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS Sbjct: 421 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS 480 Query: 481 PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG 540 PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG Sbjct: 481 PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG 540 Query: 541 TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA 600 TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA Sbjct: 541 TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA 600 Query: 601 DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 651 DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL Sbjct: 601 DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 651 >gi|20070356 numb homolog isoform 3 [Homo sapiens] Length = 640 Score = 1291 bits (3342), Expect = 0.0 Identities = 640/651 (98%), Positives = 640/651 (98%), Gaps = 11/651 (1%) Query: 1 MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60 MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED Sbjct: 1 MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60 Query: 61 AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 120 AVKRLKA TGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD Sbjct: 61 AVKRLKA-----------TGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 109 Query: 121 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 180 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA Sbjct: 110 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 169 Query: 181 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 240 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS Sbjct: 170 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 229 Query: 241 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 300 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE Sbjct: 230 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 289 Query: 301 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 360 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ Sbjct: 290 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 349 Query: 361 SPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQS 420 SPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQS Sbjct: 350 SPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQS 409 Query: 421 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS 480 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS Sbjct: 410 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS 469 Query: 481 PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG 540 PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG Sbjct: 470 PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG 529 Query: 541 TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA 600 TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA Sbjct: 530 TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA 589 Query: 601 DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 651 DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL Sbjct: 590 DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 640 >gi|54144627 numb homolog isoform 2 [Homo sapiens] Length = 603 Score = 1202 bits (3111), Expect = 0.0 Identities = 603/651 (92%), Positives = 603/651 (92%), Gaps = 48/651 (7%) Query: 1 MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60 MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED Sbjct: 1 MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60 Query: 61 AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 120 AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD Sbjct: 61 AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 120 Query: 121 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 180 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA Sbjct: 121 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 180 Query: 181 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 240 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS Sbjct: 181 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 240 Query: 241 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 300 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE Sbjct: 241 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 300 Query: 301 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 360 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ Sbjct: 301 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 360 Query: 361 SPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQS 420 SPTFQ GTEWGQS Sbjct: 361 SPTFQ------------------------------------------------GTEWGQS 372 Query: 421 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS 480 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS Sbjct: 373 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS 432 Query: 481 PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG 540 PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG Sbjct: 433 PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG 492 Query: 541 TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA 600 TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA Sbjct: 493 TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA 552 Query: 601 DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 651 DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL Sbjct: 553 DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 603 >gi|54144629 numb homolog isoform 4 [Homo sapiens] Length = 592 Score = 1170 bits (3028), Expect = 0.0 Identities = 592/651 (90%), Positives = 592/651 (90%), Gaps = 59/651 (9%) Query: 1 MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60 MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED Sbjct: 1 MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60 Query: 61 AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 120 AVKRLKA TGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD Sbjct: 61 AVKRLKA-----------TGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 109 Query: 121 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 180 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA Sbjct: 110 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 169 Query: 181 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 240 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS Sbjct: 170 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 229 Query: 241 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 300 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE Sbjct: 230 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 289 Query: 301 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 360 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ Sbjct: 290 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 349 Query: 361 SPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQS 420 SPTFQ GTEWGQS Sbjct: 350 SPTFQ------------------------------------------------GTEWGQS 361 Query: 421 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS 480 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS Sbjct: 362 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS 421 Query: 481 PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG 540 PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG Sbjct: 422 PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG 481 Query: 541 TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA 600 TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA Sbjct: 482 TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA 541 Query: 601 DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 651 DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL Sbjct: 542 DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 592 >gi|10863899 numb homolog (Drosophila)-like [Homo sapiens] Length = 609 Score = 566 bits (1458), Expect = e-161 Identities = 350/683 (51%), Positives = 405/683 (59%), Gaps = 147/683 (21%) Query: 1 MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60 MNKLRQS RR+K YVPEASRPHQWQ DE+ VR G CSFPV+YLGHVEV+ESRGMH+CED Sbjct: 42 MNKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCED 101 Query: 61 AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 120 AVK+LKA G+K+VK+VLWVSADGLRVVD+KTKDL+VDQTIEKVSFCAPD Sbjct: 102 AVKKLKA-----------MGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPD 150 Query: 121 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 180 RN D+AFSYICRDGTTRRWICHCF+A+KD+GERLSHAVGCAFAACLERKQ+REKECGVTA Sbjct: 151 RNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTA 210 Query: 181 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 240 FDASRT+F REGSFR++ AERE D KKAE +VAPG P Sbjct: 211 AFDASRTSFAREGSFRLSGGGRPAERE-----APDKKKAEA---AAAPTVAPGPAQPGHV 262 Query: 241 SPTSPTSDATTSLEMNNP-------HAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQ 293 SPT T+ E P AIPRRHAP+EQL RQGSFRGFPALSQK SPFKRQ Sbjct: 263 SPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQ 322 Query: 294 LSLRINELPSTMQRKTDFPIKNAVPEVE----GEAESISSLCSQITNAFSTPEDPFSSAP 349 LSLR+NELPST+QR+TDF +K VPE+E G+++SI++LC+QI+++F++ P AP Sbjct: 323 LSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAP---AP 379 Query: 350 MTKPVTVVAPQSPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEIA 409 P T GT SA+ + P A P Sbjct: 380 GPPPAT-----------TGT-SAWGEPSVPPAAAFQP----------------------- 404 Query: 410 ATCSGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQ------------ 457 GH+RTPSEA+RWLEEVS+ +AQQ Q Sbjct: 405 ----------------------GHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQ 442 Query: 458 -----ASAAP---LQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQ 509 AS AP + P LQP P A+P Q FL P +QP FVPA Sbjct: 443 QQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPP--------PHMQPPFVPA- 493 Query: 510 SYPVANGMPY-PAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEAS 568 YP G+ Y P P VPVVGITPSQMVAN F +A Q P + L + FP Sbjct: 494 -YP---GLGYPPMPRVPVVGITPSQMVANAFCSAAQLQ---PQPATLLGKAGAFPPPAIP 546 Query: 569 SATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSK 628 SA S P NG+ P +DPFEAQWAALE K+ Sbjct: 547 SAPGSQARPRP----NGAPW-------------PPEPAPAPAPELDPFEAQWAALEGKA- 588 Query: 629 QRTNPSPTNPFSSDLQKTFEIEL 651 T P+NPFS DLQKTFEIEL Sbjct: 589 --TVEKPSNPFSGDLQKTFEIEL 609 >gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Homo sapiens] Length = 304 Score = 83.6 bits (205), Expect = 5e-16 Identities = 63/264 (23%), Positives = 125/264 (47%), Gaps = 31/264 (11%) Query: 4 LRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVK 63 + ++F RKKD W E + + K+LG EV++ +G + DAV+ Sbjct: 1 MNRAFSRKKD---------KTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVR 51 Query: 64 RLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNF 123 +LK R K G+K K L +S G+++++ KTK++ + + ++SFCA D+ Sbjct: 52 KLKFARHIKKS----EGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTD 107 Query: 124 DRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTATFD 183 R F++IC+D + + +C+ F + K E ++ +G AF + ++ E G Sbjct: 108 KRIFTFICKDSESNKHLCYVFDSEK-CAEEITLTIGQAF----DLAYRKFLESG------ 156 Query: 184 ASRTTFTREGSFRVTTATEQAERE--EIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPSS 241 + TR+ + + E E E+ ++QD + +++ + AP + +P S Sbjct: 157 -GKDVETRKQIAGLQKRIQDLETENMELKNKVQDLE----NQLRITQVSAPPAGSMTPKS 211 Query: 242 PTSPTSDATTSLEMNNPHAIPRRH 265 P++ D +++ ++P R+ Sbjct: 212 PSTDIFDMIPFSPISHQSSMPTRN 235 >gi|132626790 low density lipoprotein receptor adaptor protein 1 [Homo sapiens] Length = 308 Score = 74.3 bits (181), Expect = 3e-13 Identities = 63/243 (25%), Positives = 103/243 (42%), Gaps = 35/243 (14%) Query: 22 PHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGK 81 P W E + G F +KYLG V++ +G + A+KR+ A K +GK Sbjct: 32 PENWTDTRETLLEGML-FSLKYLGMTLVEQPKGEELSAAAIKRIVATAK-------ASGK 83 Query: 82 KAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWIC 141 K K L VS G+ + D T LI + +I ++S+C D+ D+ F+YI + + C Sbjct: 84 KLQKVTLKVSPRGIILTDNLTNQLIENVSIYRISYCTADKMHDKVFAYIAQSQHNQSLEC 143 Query: 142 HCFMAVK-DTGERLSHAVGCAFAACLE--RKQKREKECGVTATFDASRTTFTREGSFRVT 198 H F+ K + ++ V AF E + K EKE R ++EG Sbjct: 144 HAFLCTKRKMAQAVTLTVAQAFKVAFEFWQVSKEEKE---------KRDKASQEGG---- 190 Query: 199 TATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNP 258 +++ QD + + G+ + TA +P S S ++ T E+ P Sbjct: 191 ---------DVLGARQDCTPSLKSLVATGNLLDLEETAKAPLSTVS--ANTTNMDEVPRP 239 Query: 259 HAI 261 A+ Sbjct: 240 QAL 242 >gi|149773456 hypothetical protein LOC643314 [Homo sapiens] Length = 1427 Score = 57.0 bits (136), Expect = 5e-08 Identities = 80/352 (22%), Positives = 126/352 (35%), Gaps = 38/352 (10%) Query: 231 APGNTAPSPSSPTSPTSDATTSLEMNNPHA-IPRRHAPIEQLARQGSFRGFPALSQKMSP 289 +P P+P PTSP + T E +P A +P P A P + SP Sbjct: 1041 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA------AVPTPEEPTSP 1094 Query: 290 FKRQLSLRINELPSTMQRKTDFPIKNA--VPEVEGEAESISSLCSQITNAFSTPEDPFSS 347 + P+ + P A VP E A +++ + AF P P Sbjct: 1095 AAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPE 1154 Query: 348 APMTKPVTVVAPQSPTFQANGTDSAFHVLAKPAHTA--LAPVAMPVRETNPWAHAPDAAN 405 + V V P+ A + PA +A A VA T+P A P A Sbjct: 1155 ESASAAVAVPTPEESASPAAAVPT-------PAESASFAAVVATLEEPTSPAASVPTPAA 1207 Query: 406 -----KEIAATCSGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQ-QPQAS 459 +E + + + + + + +P+ A LEE + S A P+ Sbjct: 1208 MVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEEL 1267 Query: 460 AAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPY 519 ++P V P +PASP + L P VP + A +PA S P Sbjct: 1268 SSPAASVPTP------EEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPE---- 1317 Query: 520 PAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSAT 571 P +P + P + V+ + G +AH P + ++ P E +S+T Sbjct: 1318 -VPAIPAAAVPPMEEVSPI-GVPFLGVSAHTDSVP--ISEEGTPVLEEASST 1365 Score = 49.7 bits (117), Expect = 9e-06 Identities = 76/310 (24%), Positives = 107/310 (34%), Gaps = 36/310 (11%) Query: 340 TPEDPFSSAPMTKPVTVVAPQSPTFQANGTDSAFHVLAKPAHTALAPVAMPVRE--TNPW 397 T ED P+T TV AP+ P D+A ++ P A A+P E T+P Sbjct: 965 TEEDGTPEGPVTPATTVHAPEEP-------DTAAVRVSTPEEPASPAAAVPTPEEPTSPA 1017 Query: 398 AHAPDAAN-KEIAATCSGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRA--- 453 A P AA E S AA P +P+ A EE + A Sbjct: 1018 AAVPTPEEPTSPAAAVPPPEEPTSPAAAVP---TPEEPTSPAAAVPTPEEPTSPAAAVPT 1074 Query: 454 -QQPQASAAPLQPVLQPPPPTAI----SQPASPFQGNAFLTSQPVPVGVVPALQPAFVPA 508 ++P + AA + +P P A +P SP P VP + PA Sbjct: 1075 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPA 1134 Query: 509 QSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEAS 568 + P +PAP VP + S VA P +S S P AS Sbjct: 1135 AAVPTPEEPAFPAPAVPTPEESASAAVA----------VPTPEESASPAAAVPTPAESAS 1184 Query: 569 SATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSK 628 A + P AA +A+ + T P + P A AA + + Sbjct: 1185 FAAVVATLEEP----TSPAASVPTPAAMVATLEEFTS-PAASVPTSEEPASLAAAVSNPE 1239 Query: 629 QRTNPSPTNP 638 + T+P+ P Sbjct: 1240 EPTSPAAAVP 1249 >gi|50511947 cajalin 2 isoform b [Homo sapiens] Length = 510 Score = 56.6 bits (135), Expect = 7e-08 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 5/129 (3%) Query: 19 ASRPHQ-WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFG 77 AS P Q WQ E + C + YLG + + E RG +DA +++A + Sbjct: 291 ASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKST---- 346 Query: 78 KTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTR 137 + KK +L VS G++ +D K++I + I +S A D F+YI +D + Sbjct: 347 EQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSN 406 Query: 138 RWICHCFMA 146 CH F A Sbjct: 407 HHYCHVFTA 415 >gi|50511945 cajalin 2 isoform a [Homo sapiens] Length = 1248 Score = 56.6 bits (135), Expect = 7e-08 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 5/129 (3%) Query: 19 ASRPHQ-WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFG 77 AS P Q WQ E + C + YLG + + E RG +DA +++A + Sbjct: 1041 ASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKST---- 1096 Query: 78 KTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTR 137 + KK +L VS G++ +D K++I + I +S A D F+YI +D + Sbjct: 1097 EQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSN 1156 Query: 138 RWICHCFMA 146 CH F A Sbjct: 1157 HHYCHVFTA 1165 >gi|10047134 cajalin 2 isoform c [Homo sapiens] Length = 414 Score = 56.6 bits (135), Expect = 7e-08 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 5/129 (3%) Query: 19 ASRPHQ-WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFG 77 AS P Q WQ E + C + YLG + + E RG +DA +++A + Sbjct: 207 ASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKST---- 262 Query: 78 KTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTR 137 + KK +L VS G++ +D K++I + I +S A D F+YI +D + Sbjct: 263 EQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSN 322 Query: 138 RWICHCFMA 146 CH F A Sbjct: 323 HHYCHVFTA 331 >gi|33350928 disabled homolog 1 [Homo sapiens] Length = 555 Score = 55.5 bits (132), Expect = 2e-07 Identities = 46/149 (30%), Positives = 71/149 (47%), Gaps = 18/149 (12%) Query: 30 EGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAVLW 89 EGVR + K +G EV +RG +C+D++ +LK G K G+ K L Sbjct: 38 EGVR-----YKAKLIGIDEVSAARGDKLCQDSMMKLKG---VVAGARSK-GEHKQKIFLT 88 Query: 90 VSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYIC-RDGTTRRWICHCFMAVK 148 +S G+++ DEKT L + ++S+ A D RAF Y+C ++G H F+A+K Sbjct: 89 ISFGGIKIFDEKTGALQHHHAVHEISYIAKDITDHRAFGYVCGKEGN------HRFVAIK 142 Query: 149 --DTGERLSHAVGCAFAACLERKQKREKE 175 E + + F E KQ+ E E Sbjct: 143 TAQAAEPVILDLRDLFQLIYELKQREELE 171 >gi|140161500 ankyrin repeat and sterile alpha motif domain containing 1 [Homo sapiens] Length = 1134 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 8/123 (6%) Query: 25 WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAV 84 WQ E + C + YLG + + + RG +DA +++ + K K Sbjct: 928 WQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMK--------KIP 979 Query: 85 KAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCF 144 +L ++ G++ +D K++I + I +S A D F+YI +D T CH F Sbjct: 980 TIILSITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVF 1039 Query: 145 MAV 147 V Sbjct: 1040 STV 1042 >gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo sapiens] Length = 834 Score = 50.8 bits (120), Expect = 4e-06 Identities = 86/372 (23%), Positives = 129/372 (34%), Gaps = 56/372 (15%) Query: 224 IVVGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPAL 283 ++ S+ P +P PT T + P P++ S PA Sbjct: 248 LIPAPSMVPATDTKAP--PTLQAETTTKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAA 305 Query: 284 SQKMSPFKRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPED 343 S FK I P +++ P P V A S SSL + + T + Sbjct: 306 SSASPMFKP-----IFTAPPKSEKEGPTP---PGPSVSATAPSSSSLPTTTSTTAPTFQP 357 Query: 344 PFSSAPMTKPVTVVAPQSPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDA 403 FSS M P +V P +P F+ T + P T LA V + + D+ Sbjct: 358 VFSS--MGPPASVPLP-APFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDS 414 Query: 404 ANK--------EIAATCSGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQ 455 A+K ++++ T ++ A+ P LF A + A + + + + Sbjct: 415 ASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQ----ASAASFTPAMGSIFQFGK 470 Query: 456 PQA-----SAAPLQPVLQPPPPTAISQPASPFQG--NAFLTSQPV--------------P 494 P A + L PTA S A+ F G + TS P P Sbjct: 471 PPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTP 530 Query: 495 VGVVPALQPAFVPAQSYPVANGMPYPA--------PNVPVVGITPSQMVANVFGTAGHPQ 546 +P A P SYP AN P PA P +TPS + FG + P Sbjct: 531 TFNIPFGSSAKSPLPSYPGAN--PQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPA 588 Query: 547 AAHPHQSPSLVR 558 AA PS+++ Sbjct: 589 AAPTPAPPSMIK 600 >gi|31317301 nitric oxide synthase 1 (neuronal) adaptor protein isoform 1 [Homo sapiens] Length = 506 Score = 50.1 bits (118), Expect = 7e-06 Identities = 65/269 (24%), Positives = 112/269 (41%), Gaps = 46/269 (17%) Query: 28 DEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAV 87 +E+ + G C F KY+G ++V A++R++ E F K KK K Sbjct: 22 NEDAFQHGIC-FEAKYVGSLDVPRPNSRVEIVAAMRRIRYE------FKAKNIKKK-KVS 73 Query: 88 LWVSADGLRVVDEKTKDLIVDQTIE----------------KVSFCAPDRNFDRAFSYIC 131 + VS DG++V+ +K K L++ Q E ++ + + D + FSYI Sbjct: 74 IMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIA 133 Query: 132 RDGTTRRWICHCFMAVKDT-GERLSHAVGCAFAAC----LERKQKR-------EKECGVT 179 RDG + + C+ F + K + R+ VG AF C L+ Q+ E E Sbjct: 134 RDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSN 193 Query: 180 ATFDASRTTFTREGSFRVTTAT-EQAEREEIM-----KQMQDAKKAETDKIVVGSSVAPG 233 ++ D R G+ R +TAT E+ + + + + + + TD VG Sbjct: 194 SSGDPGRQL---TGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGKE-GGS 249 Query: 234 NTAPSPSSPTSPTSDATTSLEMNNPHAIP 262 +T S P P A+ + + + + P Sbjct: 250 HTGSKVSHPQEPMLTASPRMLLPSSSSKP 278 >gi|26051278 nuclear pore membrane protein 121 [Homo sapiens] Length = 984 Score = 50.1 bits (118), Expect = 7e-06 Identities = 82/368 (22%), Positives = 126/368 (34%), Gaps = 48/368 (13%) Query: 224 IVVGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPAL 283 ++ S+ P +P PT AT + P P++ S PA Sbjct: 399 LIPAPSMVPATDTKAP--PTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAA 456 Query: 284 SQKMSPFKRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPED 343 S FK I P +++ P P V A S SSL + + T + Sbjct: 457 SSAPPMFKP-----IFTAPPKSEKEGPTP---PGPSVTATAPSSSSLPTTTSTTAPTFQP 508 Query: 344 PFSSAPMTKPVTVVAPQSPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDA 403 FSS M P +V P +P F+ T + P T LA V + + D+ Sbjct: 509 VFSS--MGPPASVPLP-APFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDS 565 Query: 404 ANK--------EIAATCSGTEWGQSSGAASPGLFQAGHRRTPS----------------- 438 A+K ++++ T ++ A+ P LF A S Sbjct: 566 ASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPAL 625 Query: 439 EADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVV 498 + S+S+ P A+++ A S PA+ Q ++ P + Sbjct: 626 PTTTTVTTFSQSLHTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNI 685 Query: 499 PALQPAFVPAQSYPVANGMPYPA--------PNVPVVGITPSQMVANVFGTAGHPQAAHP 550 P A P SYP AN P PA P + PS + FG + P AA Sbjct: 686 PFGSSAKSPLPSYPGAN--PQPAFGAAEGQPPGAAKPALAPSFGSSFTFGNSAAPAAAPT 743 Query: 551 HQSPSLVR 558 PS+++ Sbjct: 744 PAPPSMIK 751 Score = 34.7 bits (78), Expect = 0.28 Identities = 75/365 (20%), Positives = 123/365 (33%), Gaps = 54/365 (14%) Query: 232 PGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFK 291 P TA +PSS + PT+ +TT AP Q S G PA +PF Sbjct: 483 PSVTATAPSSSSLPTTTSTT--------------APTFQPVF--SSMGPPASVPLPAPFF 526 Query: 292 RQLSLRINELPSTMQRKTDF--------PIKNAVPEVEGEAESISSLCSQITNAFSTPED 343 +Q + +T T PI +A P + ++ ++ S Sbjct: 527 KQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTT 586 Query: 344 PFSSAPMTKPVTVVAPQSPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAH-APD 402 ++ ++P APQ+ + KP P V + H A Sbjct: 587 TSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPP---ALPTTTTVTTFSQSLHTAVP 643 Query: 403 AANKEIAATCSGTEWGQSSGAASPGLFQA-----GHRRTPSEADRWLEEVSKSVRAQQPQ 457 A AA SG +G + ++P + TP+ + +KS P Sbjct: 644 TATSSSAADFSG--FGSTLATSAPATSSQPTLTFSNTSTPT-FNIPFGSSAKSPLPSYPG 700 Query: 458 ASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQ---------PVPVGVVPALQPAFVPA 508 A+ P + PP A +P G++F P P ++ + PA+VP Sbjct: 701 ANPQPAFGAAEGQPPGAAKPALAPSFGSSFTFGNSAAPAAAPTPAPPSMIKVV-PAYVPT 759 Query: 509 QSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEAS 568 +P+ G + A + + A+ FG Q A + T + A+ Sbjct: 760 PIHPIFGGATHSAFGL--------KATASAFGAPASSQPAFGGSTAVFFGAATSSGFGAT 811 Query: 569 SATTS 573 + T S Sbjct: 812 TQTAS 816 >gi|19111150 angiomotin isoform 2 [Homo sapiens] Length = 675 Score = 48.9 bits (115), Expect = 1e-05 Identities = 93/396 (23%), Positives = 144/396 (36%), Gaps = 59/396 (14%) Query: 154 LSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTREGSFRVTTATEQAEREEIMKQM 213 +SH+ ++ LE + ++E+E A++ EG + T + E++ ++K + Sbjct: 302 ISHSPNTSYDTALEARIQKEEE----EILMANKRCLDMEGRIK-TLHAQIIEKDAMIKVL 356 Query: 214 QDAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLAR 273 Q + E K S + P + S S+ S L+ Sbjct: 357 QQRSRKEPSKTEQLSCMRPAKSLMSISNAGSGL------------------------LSH 392 Query: 274 QGSFRGFPALSQKMSPFKRQLSLRI---NELPSTMQRKTDFPIKNAVPEVEGEAESISSL 330 + G P + +K + SL I + + T P+ + P + +++ S Sbjct: 393 SSTLTGSPIMEEKRDDKSWKGSLGILLGGDYRAEYVPSTPSPVPPSTPLLSAHSKTGSRD 452 Query: 331 CSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQANGTDSAFHVLAKPAHT---ALAPV 387 CS T + + AP++ P V A T +A A T A APV Sbjct: 453 CSTQTERGTESNKTAAVAPISVPAPVAAA--------ATAAAITATAATITTTMVAAAPV 504 Query: 388 AMPVRETNPWAHAPDAANKEI-AATCSGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEE 446 A+ A AP A AA S GQ AAS A PS A + Sbjct: 505 AVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAV---APSAAAAAAVQ 561 Query: 447 VSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFV 506 V+ P A A P L P P A +Q ++P Q A TS P V PA P Sbjct: 562 VA-------PAAPAPVPAPALVPVPAPAAAQASAPAQTQA-PTSAPA-VAPTPAPTPTPA 612 Query: 507 PAQSYPVANGMPYPAP---NVPVVGITPSQMVANVF 539 AQ+ A+ P P ++P + P + VF Sbjct: 613 VAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVF 648 >gi|166064029 angiomotin isoform 1 [Homo sapiens] Length = 1084 Score = 48.9 bits (115), Expect = 1e-05 Identities = 93/396 (23%), Positives = 144/396 (36%), Gaps = 59/396 (14%) Query: 154 LSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTREGSFRVTTATEQAEREEIMKQM 213 +SH+ ++ LE + ++E+E A++ EG + T + E++ ++K + Sbjct: 711 ISHSPNTSYDTALEARIQKEEE----EILMANKRCLDMEGRIK-TLHAQIIEKDAMIKVL 765 Query: 214 QDAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLAR 273 Q + E K S + P + S S+ S L+ Sbjct: 766 QQRSRKEPSKTEQLSCMRPAKSLMSISNAGSGL------------------------LSH 801 Query: 274 QGSFRGFPALSQKMSPFKRQLSLRI---NELPSTMQRKTDFPIKNAVPEVEGEAESISSL 330 + G P + +K + SL I + + T P+ + P + +++ S Sbjct: 802 SSTLTGSPIMEEKRDDKSWKGSLGILLGGDYRAEYVPSTPSPVPPSTPLLSAHSKTGSRD 861 Query: 331 CSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQANGTDSAFHVLAKPAHT---ALAPV 387 CS T + + AP++ P V A T +A A T A APV Sbjct: 862 CSTQTERGTESNKTAAVAPISVPAPVAAA--------ATAAAITATAATITTTMVAAAPV 913 Query: 388 AMPVRETNPWAHAPDAANKEI-AATCSGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEE 446 A+ A AP A AA S GQ AAS A PS A + Sbjct: 914 AVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAV---APSAAAAAAVQ 970 Query: 447 VSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFV 506 V+ P A A P L P P A +Q ++P Q A TS P V PA P Sbjct: 971 VA-------PAAPAPVPAPALVPVPAPAAAQASAPAQTQA-PTSAPA-VAPTPAPTPTPA 1021 Query: 507 PAQSYPVANGMPYPAP---NVPVVGITPSQMVANVF 539 AQ+ A+ P P ++P + P + VF Sbjct: 1022 VAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVF 1057 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 48.1 bits (113), Expect = 2e-05 Identities = 89/382 (23%), Positives = 129/382 (33%), Gaps = 63/382 (16%) Query: 238 SPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLR 297 SPS S ++ L +++P H P S P S SP +S+ Sbjct: 1380 SPSPEVSASAPGAAPLTISSP-----LHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVP 1434 Query: 298 INE-----LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTK 352 ++ +P+T+ P+ +P + + +T + S P S P Sbjct: 1435 LSSSLPISVPTTLPAPASAPL--TIP-----------ISAPLTVSASGPALLTSVTPPLA 1481 Query: 353 PVTVVAPQSPTFQANGTDSAFHVLA-----KPAHTALAPVAMPVRETNPWAHAPDAANKE 407 PV AP P+ +G + L P+ ++ P+ +H P N Sbjct: 1482 PVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVP-GLNST 1540 Query: 408 IAATCSGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVL 467 +A CS +S ASP F + P++A S S QA A PL P+ Sbjct: 1541 VAPACSPV-LVPASALASP--FPSAPNPAPAQASLLAPASSAS------QALATPLAPMA 1591 Query: 468 QPPPPTAISQPASPFQGNAFLTSQPVPVGV-------VPALQPAFVPAQSYPVANGMPYP 520 P PA P L P V VP + P+ P S A+ +P P Sbjct: 1592 APQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAP 1651 Query: 521 AP-----------NVPVVGITPS----QMVANVFGTAGHPQAAHPHQSPSLVR---QQTF 562 P PV PS Q +A A + P Q+ SL Q F Sbjct: 1652 TPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPF 1711 Query: 563 PHYEASSATTSPFFKPPAQHLN 584 P S S PAQ L+ Sbjct: 1712 PTQTLSLTPASSLVPTPAQTLS 1733 Score = 33.1 bits (74), Expect = 0.82 Identities = 46/187 (24%), Positives = 73/187 (39%), Gaps = 19/187 (10%) Query: 374 HVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQSSGAASP------G 427 H++++PAH AL P P + P + A +G ++ P G Sbjct: 1249 HLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAP-TGLSLPLAANQVPPTMVNNTG 1307 Query: 428 LFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQGNAF 487 + + R+ P + L V A +P +S P VL P P + +P G A Sbjct: 1308 VVKIVVRQAPRDG---LTPVPPLAPAPRPPSSGLP--AVLNPRPTLTPGRLPTPTLGTA- 1361 Query: 488 LTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQA 547 P P V P L+ V + S V+ P A P+ +P + +++ G A P Sbjct: 1362 RAPMPTPTLVRPLLK--LVHSPSPEVSASAPGAA---PLTISSPLHVPSSLPGPASSPMP 1416 Query: 548 AHPHQSP 554 P+ SP Sbjct: 1417 I-PNSSP 1422 >gi|148491082 disabled homolog 2 [Homo sapiens] Length = 770 Score = 47.4 bits (111), Expect = 4e-05 Identities = 32/116 (27%), Positives = 61/116 (52%), Gaps = 12/116 (10%) Query: 39 FPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVV 98 + K +G +V ++RG + +D++ +LK + G+ + + +S G++++ Sbjct: 50 YKAKLIGIDDVPDARGDKMSQDSMMKLKGMAAAGRS----QGQHKQRIWVNISLSGIKII 105 Query: 99 DEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYIC-RDGTTRRWICHCFMAVKDTGER 153 DEKT + + + K+SF A D +RAF Y+C +G H F A+K TG++ Sbjct: 106 DEKTGVIEHEHPVNKISFIARDVTDNRAFGYVCGGEGQ------HQFFAIK-TGQQ 154 >gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] Length = 987 Score = 47.0 bits (110), Expect = 6e-05 Identities = 90/382 (23%), Positives = 131/382 (34%), Gaps = 67/382 (17%) Query: 224 IVVGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPAL 283 ++ S+ P +P PT AT + P P++ S PA Sbjct: 399 LIPAPSMVPATDTKAP--PTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAA 456 Query: 284 SQKMSPFKRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPED 343 S FK I P +++ P P V A S SSL + + T + Sbjct: 457 SSASPMFKP-----IFTAPPKSEKEGPTP---PGPSVTATAPSSSSLPTTTSTTAPTFQP 508 Query: 344 PFSSAPMTKPVTVVAPQSPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDA 403 FSS M P +V P +P F+ T + P T LA V + + D+ Sbjct: 509 VFSS--MGPPASVPLP-APFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDS 565 Query: 404 ANK--------EIAATCSGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQ 455 A+K ++++ T ++ A+ P LF A + A + + + + Sbjct: 566 ASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQ----ASAASFTPAMGSIFQFGK 621 Query: 456 PQA-----SAAPLQPVLQPPPPTAISQPASPFQG--NAFLTSQPV--------------P 494 P A + L PTA S A+ F G + TS P P Sbjct: 622 PPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTP 681 Query: 495 VGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTA--GHPQAAHPHQ 552 +P A P SYP AN P PA FG A P AA P Sbjct: 682 TFNIPFGSSAKSPLPSYPGAN--PQPA-----------------FGAAEGQPPGAAKPAL 722 Query: 553 SPSLVRQQTFPHYEASSATTSP 574 +PS TF + A + T+P Sbjct: 723 TPSFGSSFTFGNSAAPAPATAP 744 >gi|21327715 transcription elongation regulator 1 isoform 1 [Homo sapiens] Length = 1098 Score = 46.2 bits (108), Expect = 9e-05 Identities = 36/107 (33%), Positives = 46/107 (42%), Gaps = 13/107 (12%) Query: 435 RTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVP 494 +TPS A + + +V P +A P+Q V QP P T PA P S P P Sbjct: 304 QTPSSA---VSVATPTVSVSTPAPTATPVQTVPQPHPQTL--PPAVPH-------SVPQP 351 Query: 495 VGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGT 541 +PA P VP P+ GMP P P V ++ I V V T Sbjct: 352 TTAIPAFPPVMVPPFRVPLP-GMPIPLPGVAMMQIVSCPYVKTVATT 397 Score = 32.3 bits (72), Expect = 1.4 Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 17/91 (18%) Query: 453 AQQPQASAAPLQPVLQPPPPTAISQ-----PASPFQGNAF---LTSQPVPVGVVPALQPA 504 A P A P+++PPPP + + P PF F + P P G+ P + P Sbjct: 33 APPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPP 92 Query: 505 FV--------PAQSYPVANGMPYPAPNVPVV 527 + P S P GM +P P +P V Sbjct: 93 HLQRPPFMPPPMSSMPPPPGMMFP-PGMPPV 122 >gi|91208420 bassoon protein [Homo sapiens] Length = 3926 Score = 45.4 bits (106), Expect = 2e-04 Identities = 45/180 (25%), Positives = 66/180 (36%), Gaps = 11/180 (6%) Query: 456 PQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVAN 515 P A QP QPP P + P Q P G PAF P SYP Sbjct: 3045 PSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEP 3104 Query: 516 GMPYP---APNVPVVGITPSQMV-ANVFGTAGHPQA--AHPHQSPSLVRQQTFP-HYEAS 568 G+P P G TP + +F +A P Q+ +Q P +YE Sbjct: 3105 GLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVI 3164 Query: 569 SATTSPFFKPPAQ-HLNGSAAFNGVDDGRLASADR---HTEVPTGTCPVDPFEAQWAALE 624 ++ P P++ +G A +G + G++ R V P P ++ + +LE Sbjct: 3165 ASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTSLE 3224 Score = 38.5 bits (88), Expect = 0.020 Identities = 63/221 (28%), Positives = 76/221 (34%), Gaps = 46/221 (20%) Query: 344 PFSSAPMTKPVTVVAPQSPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDA 403 PFS P T T VAP G + A PA + +P P + + H+P Sbjct: 1373 PFSQGPGTPATTAVAPCPA-----GLPRGYMTPASPAGSERSP--SPSSTAHSYGHSPTT 1425 Query: 404 ANKEIAATCSGTEWGQSSGAASPGLFQAGH--RRTPSEADRWLEEVSKSVRAQQPQASAA 461 AN S TE A GL AG R P A + RA AS++ Sbjct: 1426 ANYG-----SQTE---DLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSS 1477 Query: 462 P-LQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYP 520 P L P PT P F T P P PA P + G P Sbjct: 1478 PPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPA-----------PASDMPRSPGAP-- 1524 Query: 521 APNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQT 561 TPS MVA GT Q H +P LV Q++ Sbjct: 1525 ---------TPSPMVAQ--GT----QTPHRPSTPRLVWQES 1550 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 43.9 bits (102), Expect = 5e-04 Identities = 94/464 (20%), Positives = 150/464 (32%), Gaps = 78/464 (16%) Query: 179 TATFDASRTTFTREG-SFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAP 237 T+T +TT +E S T+A + A +++ + KAET ++ P T P Sbjct: 162 TSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK--PTPKAET------TTKGPALTTP 213 Query: 238 SPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLR 297 +PT+P A+T+ + P I + P ++ +P + + Sbjct: 214 KEPTPTTPKEPASTTPKEPTPTTI----------------KSAPTTPKEPAPTTTKSAPT 257 Query: 298 INELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVV 357 + P+ K P P+ + + +A +TP++P + P T Sbjct: 258 TPKEPAPTTTKEPAP---TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 314 Query: 358 APQSPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAAN--KEIAATCSGT 415 +PT T + +PA T P +E P A A KE A T Sbjct: 315 KEPAPTTPKEPTPTT---PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 371 Query: 416 EWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAI 475 ++ SP TP E P + + +P P T Sbjct: 372 PAPTTTKEPSP--------TTPKEP--------------APTTTKSAPTTTKEPAPTTTK 409 Query: 476 SQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMV 535 S P +P + + T +P P P + P P P TP + Sbjct: 410 SAPTTPKEPSPTTTKEPAPT----------TPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 459 Query: 536 ANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDG 595 T P P + ++T P T+P + L + Sbjct: 460 PT---TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP------EKLAPTTPEKPAPTT 510 Query: 596 RLASADRHTEVPTGTCPVDPF-EAQWAALENKSKQRTNPSPTNP 638 A E PT T P +P AA N K+ P+PT P Sbjct: 511 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE---PAPTTP 551 Score = 36.6 bits (83), Expect = 0.075 Identities = 78/365 (21%), Positives = 123/365 (33%), Gaps = 47/365 (12%) Query: 232 PGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSP-F 290 P T P +PT+P A T+L+ P P++ AP ++LA + S K +P Sbjct: 631 PAPTTPKEPAPTTPKGTAPTTLKEPAP-TTPKKPAP-KELAPTTTKGPTSTTSDKPAPTT 688 Query: 291 KRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPED--PFSSA 348 ++ + + P+ K P P S + + T +P++ P SA Sbjct: 689 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 748 Query: 349 PMTKPVTVVAPQSPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEI 408 T +P+ P T +A KP T A R+ AA K Sbjct: 749 EPTPKALENSPKEPGVPTTKTPAA----TKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 804 Query: 409 AATCSGTEWGQSS---------------------------GAASPGLFQAGHRRTPSEAD 441 T + TE S +P + T +E Sbjct: 805 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 864 Query: 442 RWLEEVSK-SVRAQQPQASA-APLQPVLQPPPPTAISQPASPFQGNAFLTSQPVP---VG 496 EE +K RA +A+ P +P P PT+ +P + + T+ P P Sbjct: 865 NKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT-PTPRKMTS 923 Query: 497 VVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITP-SQMVANVFGTAGH----PQAAHPH 551 +P L P A++ P PN +V + P S+ G H P P Sbjct: 924 TMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPE 983 Query: 552 QSPSL 556 +P + Sbjct: 984 VTPDM 988 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 43.9 bits (102), Expect = 5e-04 Identities = 94/464 (20%), Positives = 150/464 (32%), Gaps = 78/464 (16%) Query: 179 TATFDASRTTFTREG-SFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAP 237 T+T +TT +E S T+A + A +++ + KAET ++ P T P Sbjct: 203 TSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK--PTPKAET------TTKGPALTTP 254 Query: 238 SPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLR 297 +PT+P A+T+ + P I + P ++ +P + + Sbjct: 255 KEPTPTTPKEPASTTPKEPTPTTI----------------KSAPTTPKEPAPTTTKSAPT 298 Query: 298 INELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVV 357 + P+ K P P+ + + +A +TP++P + P T Sbjct: 299 TPKEPAPTTTKEPAP---TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 355 Query: 358 APQSPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAAN--KEIAATCSGT 415 +PT T + +PA T P +E P A A KE A T Sbjct: 356 KEPAPTTPKEPTPTT---PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 412 Query: 416 EWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAI 475 ++ SP TP E P + + +P P T Sbjct: 413 PAPTTTKEPSP--------TTPKEP--------------APTTTKSAPTTTKEPAPTTTK 450 Query: 476 SQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMV 535 S P +P + + T +P P P + P P P TP + Sbjct: 451 SAPTTPKEPSPTTTKEPAPT----------TPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 500 Query: 536 ANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDG 595 T P P + ++T P T+P + L + Sbjct: 501 PT---TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP------EKLAPTTPEKPAPTT 551 Query: 596 RLASADRHTEVPTGTCPVDPF-EAQWAALENKSKQRTNPSPTNP 638 A E PT T P +P AA N K+ P+PT P Sbjct: 552 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE---PAPTTP 592 Score = 36.6 bits (83), Expect = 0.075 Identities = 78/365 (21%), Positives = 123/365 (33%), Gaps = 47/365 (12%) Query: 232 PGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSP-F 290 P T P +PT+P A T+L+ P P++ AP ++LA + S K +P Sbjct: 672 PAPTTPKEPAPTTPKGTAPTTLKEPAP-TTPKKPAP-KELAPTTTKGPTSTTSDKPAPTT 729 Query: 291 KRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPED--PFSSA 348 ++ + + P+ K P P S + + T +P++ P SA Sbjct: 730 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 789 Query: 349 PMTKPVTVVAPQSPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEI 408 T +P+ P T +A KP T A R+ AA K Sbjct: 790 EPTPKALENSPKEPGVPTTKTPAA----TKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 845 Query: 409 AATCSGTEWGQSS---------------------------GAASPGLFQAGHRRTPSEAD 441 T + TE S +P + T +E Sbjct: 846 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 905 Query: 442 RWLEEVSK-SVRAQQPQASA-APLQPVLQPPPPTAISQPASPFQGNAFLTSQPVP---VG 496 EE +K RA +A+ P +P P PT+ +P + + T+ P P Sbjct: 906 NKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT-PTPRKMTS 964 Query: 497 VVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITP-SQMVANVFGTAGH----PQAAHPH 551 +P L P A++ P PN +V + P S+ G H P P Sbjct: 965 TMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPE 1024 Query: 552 QSPSL 556 +P + Sbjct: 1025 VTPDM 1029 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 43.9 bits (102), Expect = 5e-04 Identities = 94/464 (20%), Positives = 150/464 (32%), Gaps = 78/464 (16%) Query: 179 TATFDASRTTFTREG-SFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAP 237 T+T +TT +E S T+A + A +++ + KAET ++ P T P Sbjct: 255 TSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK--PTPKAET------TTKGPALTTP 306 Query: 238 SPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLR 297 +PT+P A+T+ + P I + P ++ +P + + Sbjct: 307 KEPTPTTPKEPASTTPKEPTPTTI----------------KSAPTTPKEPAPTTTKSAPT 350 Query: 298 INELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVV 357 + P+ K P P+ + + +A +TP++P + P T Sbjct: 351 TPKEPAPTTTKEPAP---TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 407 Query: 358 APQSPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAAN--KEIAATCSGT 415 +PT T + +PA T P +E P A A KE A T Sbjct: 408 KEPAPTTPKEPTPTT---PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 464 Query: 416 EWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAI 475 ++ SP TP E P + + +P P T Sbjct: 465 PAPTTTKEPSP--------TTPKEP--------------APTTTKSAPTTTKEPAPTTTK 502 Query: 476 SQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMV 535 S P +P + + T +P P P + P P P TP + Sbjct: 503 SAPTTPKEPSPTTTKEPAPT----------TPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 552 Query: 536 ANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDG 595 T P P + ++T P T+P + L + Sbjct: 553 PT---TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP------EKLAPTTPEKPAPTT 603 Query: 596 RLASADRHTEVPTGTCPVDPF-EAQWAALENKSKQRTNPSPTNP 638 A E PT T P +P AA N K+ P+PT P Sbjct: 604 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE---PAPTTP 644 Score = 36.6 bits (83), Expect = 0.075 Identities = 78/365 (21%), Positives = 123/365 (33%), Gaps = 47/365 (12%) Query: 232 PGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSP-F 290 P T P +PT+P A T+L+ P P++ AP ++LA + S K +P Sbjct: 724 PAPTTPKEPAPTTPKGTAPTTLKEPAP-TTPKKPAP-KELAPTTTKGPTSTTSDKPAPTT 781 Query: 291 KRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPED--PFSSA 348 ++ + + P+ K P P S + + T +P++ P SA Sbjct: 782 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 841 Query: 349 PMTKPVTVVAPQSPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEI 408 T +P+ P T +A KP T A R+ AA K Sbjct: 842 EPTPKALENSPKEPGVPTTKTPAA----TKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 897 Query: 409 AATCSGTEWGQSS---------------------------GAASPGLFQAGHRRTPSEAD 441 T + TE S +P + T +E Sbjct: 898 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 957 Query: 442 RWLEEVSK-SVRAQQPQASA-APLQPVLQPPPPTAISQPASPFQGNAFLTSQPVP---VG 496 EE +K RA +A+ P +P P PT+ +P + + T+ P P Sbjct: 958 NKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT-PTPRKMTS 1016 Query: 497 VVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITP-SQMVANVFGTAGH----PQAAHPH 551 +P L P A++ P PN +V + P S+ G H P P Sbjct: 1017 TMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPE 1076 Query: 552 QSPSL 556 +P + Sbjct: 1077 VTPDM 1081 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 43.9 bits (102), Expect = 5e-04 Identities = 94/464 (20%), Positives = 150/464 (32%), Gaps = 78/464 (16%) Query: 179 TATFDASRTTFTREG-SFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAP 237 T+T +TT +E S T+A + A +++ + KAET ++ P T P Sbjct: 296 TSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK--PTPKAET------TTKGPALTTP 347 Query: 238 SPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLR 297 +PT+P A+T+ + P I + P ++ +P + + Sbjct: 348 KEPTPTTPKEPASTTPKEPTPTTI----------------KSAPTTPKEPAPTTTKSAPT 391 Query: 298 INELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVV 357 + P+ K P P+ + + +A +TP++P + P T Sbjct: 392 TPKEPAPTTTKEPAP---TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 448 Query: 358 APQSPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAAN--KEIAATCSGT 415 +PT T + +PA T P +E P A A KE A T Sbjct: 449 KEPAPTTPKEPTPTT---PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 505 Query: 416 EWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAI 475 ++ SP TP E P + + +P P T Sbjct: 506 PAPTTTKEPSP--------TTPKEP--------------APTTTKSAPTTTKEPAPTTTK 543 Query: 476 SQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMV 535 S P +P + + T +P P P + P P P TP + Sbjct: 544 SAPTTPKEPSPTTTKEPAPT----------TPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 593 Query: 536 ANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDG 595 T P P + ++T P T+P + L + Sbjct: 594 PT---TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP------EKLAPTTPEKPAPTT 644 Query: 596 RLASADRHTEVPTGTCPVDPF-EAQWAALENKSKQRTNPSPTNP 638 A E PT T P +P AA N K+ P+PT P Sbjct: 645 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE---PAPTTP 685 Score = 36.6 bits (83), Expect = 0.075 Identities = 78/365 (21%), Positives = 123/365 (33%), Gaps = 47/365 (12%) Query: 232 PGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSP-F 290 P T P +PT+P A T+L+ P P++ AP ++LA + S K +P Sbjct: 765 PAPTTPKEPAPTTPKGTAPTTLKEPAP-TTPKKPAP-KELAPTTTKGPTSTTSDKPAPTT 822 Query: 291 KRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPED--PFSSA 348 ++ + + P+ K P P S + + T +P++ P SA Sbjct: 823 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 882 Query: 349 PMTKPVTVVAPQSPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEI 408 T +P+ P T +A KP T A R+ AA K Sbjct: 883 EPTPKALENSPKEPGVPTTKTPAA----TKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 938 Query: 409 AATCSGTEWGQSS---------------------------GAASPGLFQAGHRRTPSEAD 441 T + TE S +P + T +E Sbjct: 939 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 998 Query: 442 RWLEEVSK-SVRAQQPQASA-APLQPVLQPPPPTAISQPASPFQGNAFLTSQPVP---VG 496 EE +K RA +A+ P +P P PT+ +P + + T+ P P Sbjct: 999 NKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT-PTPRKMTS 1057 Query: 497 VVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITP-SQMVANVFGTAGH----PQAAHPH 551 +P L P A++ P PN +V + P S+ G H P P Sbjct: 1058 TMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPE 1117 Query: 552 QSPSL 556 +P + Sbjct: 1118 VTPDM 1122 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 43.9 bits (102), Expect = 5e-04 Identities = 88/345 (25%), Positives = 118/345 (34%), Gaps = 67/345 (19%) Query: 226 VGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQG-SFRGFPALS 284 V S+ T PSP++ P++ L+ ++ P+ AR G S RG P Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGG--GLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266 Query: 285 QKMSPFKRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDP 344 S K + L + + P K+A P + P Sbjct: 267 AHPSQPKPK------GLQALRPPQVTPPRKDAAPAL----------------------GP 298 Query: 345 FSSAPMTKPVTVVAPQS---PTFQANGTDSAFHV-LAKPAHTAL-APVAMPVRETNPWAH 399 SS+P+ P A QS PT A S+ LA P A +P A P +T P Sbjct: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLP--- 355 Query: 400 APDAANKEIAATCSGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQAS 459 +P A A T G SP L QA H PS + PQA Sbjct: 356 SPPATPPSQATTSLG----------SPTL-QATHSFLPSPP-------LSPLATPPPQAP 397 Query: 460 AAPLQPVLQPPP---------PTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQS 510 A P LQ PP P A P +P L P P +Q F P S Sbjct: 398 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 457 Query: 511 YPVANGMPYPAPNVPVVGITPSQMVANVFGTAG-HPQAAHPHQSP 554 PV+ P+ P + P Q+ + + P A P Q+P Sbjct: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 502 Score = 35.0 bits (79), Expect = 0.22 Identities = 89/376 (23%), Positives = 128/376 (34%), Gaps = 39/376 (10%) Query: 233 GNTAPSPSSPTSPTSDATTSLE--MNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPF 290 G A P T P DA +L ++P A P A ++ A + P S Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPP-TLPATPHSSSLTCQL 334 Query: 291 KRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAF--STPEDPFSSA 348 L L PS P A P + S+ S Q T++F S P P ++ Sbjct: 335 ATPLPLAPPS-PSAPPSLQTLPSPPATPPSQATT-SLGSPTLQATHSFLPSPPLSPLATP 392 Query: 349 PMTKPVTVVAP--QSPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANK 406 P P + P Q+P + PA L+P+A P + P A A Sbjct: 393 PPQAPPALALPPLQAPP-------------SPPASPPLSPLATPSPQA-PNALAVHLLQA 438 Query: 407 EIAATCSGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPV 466 + S S ASP + + PS+A L V P A+P Sbjct: 439 PFSPPPSPPVQAPFSPPASPPVSPSA--TPPSQAPPSLAAPPLQV---PPSPPASPPMSP 493 Query: 467 LQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPY-PAPNVP 525 PPP A A+P A Q P P LQ P S+P P+ P+ ++P Sbjct: 494 SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP--GQAPFSPSASLP 551 Query: 526 VVGI-TPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFF-------K 577 + + TP V P SP+L + P ++ + P Sbjct: 552 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 611 Query: 578 PPAQHLNGSAAFNGVD 593 PP + S+ +G D Sbjct: 612 PPPPSRSPSSTLSGPD 627 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 43.9 bits (102), Expect = 5e-04 Identities = 98/401 (24%), Positives = 136/401 (33%), Gaps = 57/401 (14%) Query: 231 APGNTAPS--PSSPTSPTSDATTSLE----MNNPHAI--PRRHAPIEQLARQG----SFR 278 +P T PS P S T+P A SL+ + PH++ P AP LA + Sbjct: 359 SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418 Query: 279 GFPALSQK-----MSPFKRQLSLRINELPST-------MQRKTDFPIKNAVPEVEGEAES 326 G P L MSP + Q SL P++ +Q P + P + + Sbjct: 419 GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPA--SPPLQTSLSPA 476 Query: 327 ISSLCSQITN---------AFSTPEDPFSSA---PMTKPVTVVAPQSPTFQANGTDSAFH 374 +S L S +T A +P+ P SS P+ ++ P T A+ T Sbjct: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE 536 Query: 375 VLAK----PAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQSSGA----ASP 426 L P TA AP+ P ET P T E S A P Sbjct: 537 NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPP 596 Query: 427 GLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPP-----PTAISQPASP 481 L + PS L ++ P + PLQ PP P A P +P Sbjct: 597 ALASPPLQGLPSPP---LSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP 653 Query: 482 FQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGT 541 L P P +Q F P S PV+ P+ P + P Q+ + + Sbjct: 654 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 713 Query: 542 AG-HPQAAHPHQSPSLVRQQTF--PHYEASSATTSPFFKPP 579 P A P Q+P + P +S SP PP Sbjct: 714 PPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP 754 Score = 38.9 bits (89), Expect = 0.015 Identities = 83/391 (21%), Positives = 140/391 (35%), Gaps = 75/391 (19%) Query: 226 VGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQG-SFRGFPALS 284 V S+ T PSP++ P++ L+ ++ P+ AR G S RG P Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGG--GLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266 Query: 285 Q----------------KMSPFKRQLSLRINEL---------PSTMQRKTDFPIKNAVPE 319 +++P ++ + + L PS + + P NA Sbjct: 267 AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATP 326 Query: 320 VEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQANGTDSAFHVLAKP 379 + L + + A +P P S + P P +P QA + + + A P Sbjct: 327 LPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP-----PATPPSQAPPSMTTPPMQAPP 381 Query: 380 AHTALAPVAMPVRETNPWAHAPDA--ANKEIAATCSGTEWGQSSGAASPGLFQAGHRRTP 437 + + P+ +P T+P AP + A + AT T G + A+ R+T Sbjct: 382 SLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQAT---TSLGSPTLQATHSFLTMSPRQTQ 438 Query: 438 SEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGV 497 + S+ + AS P P LQ P +S PASP P+ + Sbjct: 439 A-----------SLTSPSRPASTPPDSPPLQAP----LSLPASP----------PLQTSL 473 Query: 498 VPALQPAFVPAQSYPV--ANGMPYPAPNVPVVGI------TPSQMVANVFGTAGHPQAAH 549 PA+ P P +P+ + + +P P+ + T S + T Sbjct: 474 SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533 Query: 550 PHQS-PSLVRQQTFPHYEASSATTSPFFKPP 579 P ++ PSL P AS+ T+P + P Sbjct: 534 PLENLPSLAPP---PLQTASAPLTTPHLETP 561 Score = 34.7 bits (78), Expect = 0.28 Identities = 73/303 (24%), Positives = 107/303 (35%), Gaps = 34/303 (11%) Query: 231 APGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPF 290 AP PS T+P + +S+ P A P +P +G P S +SP Sbjct: 565 APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP--------PLQGLP--SPPLSPL 614 Query: 291 -----KRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNA-FSTPEDP 344 + L + L + P+ P ++ ++L + A FS P P Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLS---PLATPSPQAPNALAVHLLQAPFSPPPSP 671 Query: 345 FSSAPMTKPVTVVAPQSPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAA 404 AP + P + S T + S + A P +P A P +P A P A Sbjct: 672 PVQAPFSPPASPPVSPSATPPSQAPPS---LAAPPLQVPPSPPASP--PMSPSATPPPQA 726 Query: 405 NKEIAATCSGTEWGQSSGAASPGLFQAGHR--RTPSEADRWLEEVSKSVRAQQPQASAA- 461 +AA S ASP + + R P +V S A P + A Sbjct: 727 PPPLAAPPLQVP---PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAK 783 Query: 462 -PLQ--PVLQPPPPTAISQPASPFQGNA-FLTSQPVPVGVVPALQPAFVPAQSYPVANGM 517 P Q P L PP A+ P + F G A F S +P+ + P P + P+ Sbjct: 784 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 843 Query: 518 PYP 520 P P Sbjct: 844 PSP 846 Score = 34.3 bits (77), Expect = 0.37 Identities = 56/253 (22%), Positives = 91/253 (35%), Gaps = 12/253 (4%) Query: 393 ETNPWAHAPDAANKEIAATCSGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVR 452 E +P A +A + S + ++ +SP R TP + K ++ Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278 Query: 453 AQQPQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYP 512 A +P P + P + S A+P P P L PA +P S P Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPL-PATLPP-SPP 336 Query: 513 VANGMPY--PAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSA 570 +A +P P+P+ P T A A P Q+P + QT P + + Sbjct: 337 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSL--QTIPPIQVPHS 394 Query: 571 TTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSKQR 630 TSP + P L S+ G H+ + + P + Q A+L + S+ Sbjct: 395 LTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFL-----TMSPRQTQ-ASLTSPSRPA 448 Query: 631 TNPSPTNPFSSDL 643 + P + P + L Sbjct: 449 STPPDSPPLQAPL 461 Score = 33.9 bits (76), Expect = 0.48 Identities = 50/205 (24%), Positives = 73/205 (35%), Gaps = 24/205 (11%) Query: 318 PEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQANGTDSAFHVLA 377 P EG +S+SS + ST E S A +P Q P + S+ L+ Sbjct: 200 PPTEGPRKSVSS-----ASEHSTTEP--SPAARRRPSAGGGLQRPA--SRSLSSSATPLS 250 Query: 378 KPAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQSSGAASPGLFQAGHRRTP 437 PA + + P +P P A + A + G + TP Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQ---ALRPPQVTPPRKDAAPALGPLSSSPLATP 307 Query: 438 SEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGV 497 S + +K+ P +A PL L P PP A P +P +A + Q +P Sbjct: 308 SPSG------TKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLP--- 358 Query: 498 VPALQPAFVPAQSYPVANGMPYPAP 522 PA P+Q+ P P AP Sbjct: 359 ---SPPATPPSQAPPSMTTPPMQAP 380 >gi|91208418 transcription elongation regulator 1 isoform 2 [Homo sapiens] Length = 1077 Score = 43.9 bits (102), Expect = 5e-04 Identities = 34/97 (35%), Positives = 44/97 (45%), Gaps = 14/97 (14%) Query: 435 RTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVP 494 +TPS A + + +V P +A P+Q V QP P T PA P S P P Sbjct: 304 QTPSSA---VSVATPTVSVSTPAPTATPVQTVPQPHPQTL--PPAVPH-------SVPQP 351 Query: 495 VGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITP 531 +PA P VP P+ GMP P P V + G+ P Sbjct: 352 TTAIPAFPPVMVPPFRVPLP-GMPIPLPGV-LPGMAP 386 Score = 32.3 bits (72), Expect = 1.4 Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 17/91 (18%) Query: 453 AQQPQASAAPLQPVLQPPPPTAISQ-----PASPFQGNAF---LTSQPVPVGVVPALQPA 504 A P A P+++PPPP + + P PF F + P P G+ P + P Sbjct: 33 APPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPP 92 Query: 505 FV--------PAQSYPVANGMPYPAPNVPVV 527 + P S P GM +P P +P V Sbjct: 93 HLQRPPFMPPPMSSMPPPPGMMFP-PGMPPV 122 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.128 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,923,418 Number of Sequences: 37866 Number of extensions: 1477886 Number of successful extensions: 10417 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 48 Number of HSP's successfully gapped in prelim test: 522 Number of HSP's that attempted gapping in prelim test: 8444 Number of HSP's gapped (non-prelim): 1984 length of query: 651 length of database: 18,247,518 effective HSP length: 109 effective length of query: 542 effective length of database: 14,120,124 effective search space: 7653107208 effective search space used: 7653107208 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.