Guide to the Human Genome
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Name: NUMBL Sequence: fasta or formatted (609aa) NCBI GI: 10863899
Description:

numb homolog (Drosophila)-like

Referenced in:

Notch Pathway
Additional Membrane Functions

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            13.8         84           4
 C cysteine            2.1         13           1
 D aspartate           3.4         21           2
 E glutamate           5.9         36           2
 F phenylalanine       3.8         23           1
 G glycine             7.4         45           3
 H histidine           1.6         10           1
 I isoleucine          1.5          9           1
 K lysine              4.6         28           3
 L leucine             5.7         35           2
 M methionine          1.5          9           1
 N asparagine          1.3          8           1
 P proline            13.5         82           3
 Q glutamine           7.4         45          20
 R arginine            6.7         41           3
 S serine              6.9         42           3
 T threonine           4.9         30           2
 V valine              5.9         36           2
 W tryptophan          1.1          7           1
 Y tyrosine            0.8          5           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   numb homolog (Drosophila)-like 
NUMB                  0.467   numb homolog isoform 4 
NUMB                  0.460   numb homolog isoform 2 
NUMB                  0.448   numb homolog isoform 3 
NUMB                  0.442   numb homolog isoform 1 
GULP1                 0.043   GULP, engulfment adaptor PTB domain containing 1 [Hom...
ATN1                  0.037   atrophin-1 
ATN1                  0.037   atrophin-1 
LDLRAP1               0.037   low density lipoprotein receptor adaptor protein 1 ...
FLJ22184              0.036   PREDICTED: hypothetical protein FLJ22184 
MED15                 0.036   mediator complex subunit 15 isoform b 
NCOA6                 0.034   nuclear receptor coactivator 6 
MN1                   0.034   meningioma  1 
EP400                 0.033   E1A binding protein p400 
MED15                 0.033   mediator complex subunit 15 isoform a 
MNT                   0.033   MAX binding protein 
BAT2                  0.033   HLA-B associated transcript-2 
RAPH1                 0.033   Ras association and pleckstrin homology domains 1 is...
CREBBP                0.033   CREB binding protein isoform b 
CREBBP                0.033   CREB binding protein isoform a 
NACA                  0.033   nascent polypeptide-associated complex alpha subuni...
FLJ22184              0.033   PREDICTED: hypothetical protein LOC80164 
MAP7D1                0.032   MAP7 domain containing 1 
HTT                   0.031   huntingtin 
FMN2                  0.030   formin 2 
KIAA1522              0.030   hypothetical protein LOC57648 
SMARCC2               0.029   SWI/SNF-related matrix-associated actin-dependent re...
AAK1                  0.029   AP2 associated kinase 1 
NCOA3                 0.029   nuclear receptor coactivator 3 isoform a 
ANKS1B                0.029   cajalin 2 isoform b 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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