Guide to the Human Genome
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Name: NUMB Sequence: fasta or formatted (651aa) NCBI GI: 54144625
Description:

numb homolog isoform 1

Referenced in:

Notch Pathway
Additional Membrane Functions
PDZ Domain

Other entries for this name:
alt prot [640aa] numb homolog isoform 3
alt prot [603aa] numb homolog isoform 2
alt prot [592aa] numb homolog isoform 4
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            11.4         74           2
 C cysteine            1.8         12           1
 D aspartate           4.0         26           2
 E glutamate           6.0         39           2
 F phenylalanine       5.2         34           2
 G glycine             5.2         34           1
 H histidine           2.6         17           1
 I isoleucine          2.6         17           1
 K lysine              5.5         36           2
 L leucine             4.5         29           1
 M methionine          1.8         12           1
 N asparagine          3.1         20           2
 P proline             9.7         63           4
 Q glutamine           5.7         37           2
 R arginine            5.7         37           2
 S serine              8.6         56           2
 T threonine           7.4         48           2
 V valine              7.2         47           2
 W tryptophan          1.1          7           1
 Y tyrosine            0.9          6           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   numb homolog isoform 1 
NUMB                  0.975   numb homolog isoform 3 
NUMB                  0.907   numb homolog isoform 2 
NUMB                  0.882   numb homolog isoform 4 
NUMBL                 0.417   numb homolog (Drosophila)-like 
GULP1                 0.045   GULP, engulfment adaptor PTB domain containing 1 [Hom...
LDLRAP1               0.038   low density lipoprotein receptor adaptor protein 1 ...
KIAA0754              0.025   hypothetical protein LOC643314 
ANKS1B                0.025   cajalin 2 isoform b 
ANKS1B                0.025   cajalin 2 isoform a 
ANKS1B                0.025   cajalin 2 isoform c 
DAB1                  0.023   disabled homolog 1 
ANKS1A                0.022   ankyrin repeat and sterile alpha motif domain conta...
LOC100288540          0.020   PREDICTED: hypothetical protein XP_002342775 
NOS1AP                0.019   nitric oxide synthase 1 (neuronal) adaptor protein i...
POM121                0.019   nuclear pore membrane protein 121 
AMOT                  0.018   angiomotin isoform 2 
AMOT                  0.018   angiomotin isoform 1 
SRCAP                 0.018   Snf2-related CBP activator protein 
DAB2                  0.017   disabled homolog 2 
POM121C               0.017   POM121 membrane glycoprotein (rat)-like 
TCERG1                0.016   transcription elongation regulator 1 isoform 1 [Homo...
BSN                   0.015   bassoon protein 
PRG4                  0.015   proteoglycan 4 isoform D 
PRG4                  0.015   proteoglycan 4 isoform C 
PRG4                  0.015   proteoglycan 4 isoform B 
PRG4                  0.015   proteoglycan 4 isoform A 
FLJ22184              0.015   PREDICTED: hypothetical protein FLJ22184 
FLJ22184              0.015   PREDICTED: hypothetical protein FLJ22184 
TCERG1                0.015   transcription elongation regulator 1 isoform 2 [Homo...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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