Guide to the Human Genome
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Name: NUMB Sequence: fasta or formatted (592aa) NCBI GI: 54144629
Description:

numb homolog isoform 4

Referenced in:

Notch Pathway
Additional Membrane Functions
PDZ Domain

Other entries for this name:
alt prot [640aa] numb homolog isoform 3
alt prot [651aa] numb homolog isoform 1
alt prot [603aa] numb homolog isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            10.3         61           2
 C cysteine            1.9         11           1
 D aspartate           4.1         24           2
 E glutamate           6.1         36           2
 F phenylalanine       4.9         29           2
 G glycine             5.2         31           1
 H histidine           2.4         14           1
 I isoleucine          2.7         16           1
 K lysine              5.2         31           2
 L leucine             4.6         27           1
 M methionine          1.9         11           1
 N asparagine          2.9         17           2
 P proline             9.8         58           4
 Q glutamine           6.2         37           2
 R arginine            5.9         35           2
 S serine              9.1         54           2
 T threonine           7.4         44           2
 V valine              7.4         44           2
 W tryptophan          1.0          6           1
 Y tyrosine            1.0          6           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   numb homolog isoform 4 
NUMB                  0.992   numb homolog isoform 2 
NUMB                  0.980   numb homolog isoform 3 
NUMB                  0.973   numb homolog isoform 1 
NUMBL                 0.486   numb homolog (Drosophila)-like 
GULP1                 0.048   GULP, engulfment adaptor PTB domain containing 1 [Hom...
LDLRAP1               0.044   low density lipoprotein receptor adaptor protein 1 ...
DAB1                  0.034   disabled homolog 1 
ANKS1B                0.029   cajalin 2 isoform b 
ANKS1B                0.029   cajalin 2 isoform a 
ANKS1B                0.029   cajalin 2 isoform c 
ANKS1A                0.026   ankyrin repeat and sterile alpha motif domain conta...
BRD4                  0.024   bromodomain-containing protein 4 isoform long 
NOS1AP                0.022   nitric oxide synthase 1 (neuronal) adaptor protein i...
DAB2                  0.022   disabled homolog 2 
TCERG1                0.021   transcription elongation regulator 1 isoform 1 [Homo...
KIAA0754              0.020   hypothetical protein LOC643314 
TCERG1                0.020   transcription elongation regulator 1 isoform 2 [Homo...
PRR12                 0.020   proline rich 12 
PRG4                  0.019   proteoglycan 4 isoform D 
PRG4                  0.019   proteoglycan 4 isoform C 
PRG4                  0.019   proteoglycan 4 isoform B 
PRG4                  0.019   proteoglycan 4 isoform A 
SRCAP                 0.019   Snf2-related CBP activator protein 
BSN                   0.017   bassoon protein 
FLJ22184              0.017   PREDICTED: hypothetical protein FLJ22184 
FLJ22184              0.017   PREDICTED: hypothetical protein LOC80164 
TSC22D2               0.016   TSC22 domain family, member 2 
MUC7                  0.016   mucin 7, secreted precursor 
MUC7                  0.016   mucin 7, secreted precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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