Guide to the Human Genome
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Search of human proteins with 54112420

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|54112420 Cas-Br-M (murine) ecotropic retroviral transforming
sequence b [Homo sapiens]
         (982 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|54112420 Cas-Br-M (murine) ecotropic retroviral transforming ...  2056   0.0  
gi|52426745 Cas-Br-M (murine) ecotropic retroviral transforming ...   829   0.0  
gi|195927027 Cas-Br-M (murine) ecotropic retroviral transforming...   411   e-114
gi|195927030 Cas-Br-M (murine) ecotropic retroviral transforming...   317   5e-86
gi|47132519 Ras association and pleckstrin homology domains 1 is...    66   1e-10
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    64   5e-10
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          63   2e-09
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          63   2e-09
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          63   2e-09
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         60   1e-08
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    58   5e-08
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom...    57   6e-08
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom...    57   6e-08
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap...    57   6e-08
gi|150170670 piccolo isoform 2 [Homo sapiens]                          55   2e-07
gi|150378539 piccolo isoform 1 [Homo sapiens]                          55   2e-07
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 53   1e-06
gi|118402590 myosin XV [Homo sapiens]                                  53   2e-06
gi|33356148 formin-like 1 [Homo sapiens]                               52   2e-06
gi|151301053 RNA binding motif protein 33 [Homo sapiens]               52   3e-06
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    52   4e-06
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    52   4e-06
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    51   5e-06
gi|126090663 zinc finger homeodomain 4 [Homo sapiens]                  51   5e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    51   6e-06
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    51   6e-06
gi|4557329 fas ligand [Homo sapiens]                                   50   8e-06
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]         50   8e-06
gi|4758666 LATS homolog 1 [Homo sapiens]                               50   8e-06
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]                      50   8e-06

>gi|54112420 Cas-Br-M (murine) ecotropic retroviral transforming
           sequence b [Homo sapiens]
          Length = 982

 Score = 2056 bits (5327), Expect = 0.0
 Identities = 982/982 (100%), Positives = 982/982 (100%)

Query: 1   MANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLC 60
           MANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLC
Sbjct: 1   MANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLC 60

Query: 61  QNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKR 120
           QNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKR
Sbjct: 61  QNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKR 120

Query: 121 AIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAE 180
           AIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAE
Sbjct: 121 AIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAE 180

Query: 181 FWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLF 240
           FWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLF
Sbjct: 181 FWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLF 240

Query: 241 QPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYV 300
           QPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYV
Sbjct: 241 QPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYV 300

Query: 301 TGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQY 360
           TGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQY
Sbjct: 301 TGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQY 360

Query: 361 ELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEP 420
           ELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEP
Sbjct: 361 ELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEP 420

Query: 421 IIVDPFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESLMMNRLANVRKCTDRQNSPVTS 480
           IIVDPFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESLMMNRLANVRKCTDRQNSPVTS
Sbjct: 421 IIVDPFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESLMMNRLANVRKCTDRQNSPVTS 480

Query: 481 PGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQ 540
           PGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQ
Sbjct: 481 PGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQ 540

Query: 541 DKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVESVPSRDPPMPLEAWCPRDVFG 600
           DKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVESVPSRDPPMPLEAWCPRDVFG
Sbjct: 541 DKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVESVPSRDPPMPLEAWCPRDVFG 600

Query: 601 TNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHRRHDLPLEGAKVFSNGHL 660
           TNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHRRHDLPLEGAKVFSNGHL
Sbjct: 601 TNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHRRHDLPLEGAKVFSNGHL 660

Query: 661 GSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPVSLN 720
           GSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPVSLN
Sbjct: 661 GSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPVSLN 720

Query: 721 SQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPP 780
           SQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPP
Sbjct: 721 SQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPP 780

Query: 781 ARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPG 840
           ARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPG
Sbjct: 781 ARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPG 840

Query: 841 SSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARRLPGENVKTNRTSQDYDQLPSCSDGSQ 900
           SSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARRLPGENVKTNRTSQDYDQLPSCSDGSQ
Sbjct: 841 SSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARRLPGENVKTNRTSQDYDQLPSCSDGSQ 900

Query: 901 APARPPKPRPRRTAPEIHHRKPHGPEAALENVDAKIAKLMGEGYAFEEVKRALEIAQNNV 960
           APARPPKPRPRRTAPEIHHRKPHGPEAALENVDAKIAKLMGEGYAFEEVKRALEIAQNNV
Sbjct: 901 APARPPKPRPRRTAPEIHHRKPHGPEAALENVDAKIAKLMGEGYAFEEVKRALEIAQNNV 960

Query: 961 EVARSILREFAFPPPVSPRLNL 982
           EVARSILREFAFPPPVSPRLNL
Sbjct: 961 EVARSILREFAFPPPVSPRLNL 982


>gi|52426745 Cas-Br-M (murine) ecotropic retroviral transforming
           sequence [Homo sapiens]
          Length = 906

 Score =  829 bits (2142), Expect = 0.0
 Identities = 494/1012 (48%), Positives = 595/1012 (58%), Gaps = 172/1012 (16%)

Query: 6   NGRNPGGRGGNPRKGRILGII-DAIQDA------VGPPKQAAADRRTVEKTWKLMDKVVR 58
           +G   G   G    G ++G++ DA Q        + P      D++ VEK WKLMDKVVR
Sbjct: 9   SGAGGGSGSGGSGSGGLIGLMKDAFQPHHHHHHHLSPHPPGTVDKKMVEKCWKLMDKVVR 68

Query: 59  LCQNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKS 118
           LCQNPKL LKNSPPYILD+LPDTYQHLR ILS+Y+   K+  L ENEYF++++++LMKK+
Sbjct: 69  LCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEG--KMETLGENEYFRVFMENLMKKT 126

Query: 119 KRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADA 178
           K+ I LFKEGKERMYEE SQ RRNLTKLSLIFSHMLAE+K IFP+G FQGD FRITKADA
Sbjct: 127 KQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRITKADA 186

Query: 179 AEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTR 238
           AEFWRK FG+KTIVPWK FRQ LHEVH ISSGLEAMALKSTIDLTCNDYISVFEFDIFTR
Sbjct: 187 AEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTR 246

Query: 239 LFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIG 298
           LFQPW S+LRNWN LAVTHPGYMAFLTYDEVKARLQK+  KPGSYIFRLSCTRLGQWAIG
Sbjct: 247 LFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIG 306

Query: 299 YVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQE 358
           YVT DGNILQTIPHNKPLFQALIDG REGFYL+PDGR+ NPDLTGLCEPTP DHIKVTQE
Sbjct: 307 YVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHIKVTQE 366

Query: 359 QYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGT 418
           QYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLT+WQES+GQGCPFCRCEIKGT
Sbjct: 367 QYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRCEIKGT 426

Query: 419 EPIIVDPFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESL-MMNRLANVRKCTDRQNSP 477
           EPI+VDPFDPR  GS      +    P  D DDD+  +++L MM  LA  +   +R  SP
Sbjct: 427 EPIVVDPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDTLFMMKELAGAK--VERPPSP 484

Query: 478 VTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMV 537
            +                    P  SLPPVPPRLDL+ + +      S  G+   +    
Sbjct: 485 FS------------------MAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGS 526

Query: 538 RKQDKPLPAPPPPLRD-PPPPPPERPPPIPPDNRLSRHIHHVE--SVPSRD--PPMPL-- 590
             +DKPLP  PP LRD PPPPPP+RP  +  ++R  R          PSRD  PP+P   
Sbjct: 527 LHKDKPLPV-PPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSR 585

Query: 591 --EAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSN--------VNGRHSRVGSDPVLMR 640
             ++W PR +                PK  ++A S+        +  RHS   S P  M 
Sbjct: 586 LGDSWLPRPI----------------PKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQME 629

Query: 641 KHRRHDLP-------LEGAKVFSNGHLGSEEYDVPPRLSP-------------PPPVTTL 680
              R D+P       L+ +   ++  L   E D  P++ P             P PV  L
Sbjct: 630 P--RPDVPRLGSTFSLDTSMSMNSSPLVGPECD-HPKIKPSSSANAIYSLAARPLPVPKL 686

Query: 681 LPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPV-SLNSQPSHCHNVKPPVRSCDNG 739
            P  +C G               E+D EY  PSS P+  L++  S         R+CD  
Sbjct: 687 PPGEQCEG---------------EEDTEYMTPSSRPLRPLDTSQSS--------RACDCD 723

Query: 740 HCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTP 799
             + + T+      +S  P ++   +   F   +         P   +N   G       
Sbjct: 724 QQIDSCTYEAMYNIQSQAPSIT---ESSTFGEGNLAAAHANTGPEESENEDDG------- 773

Query: 800 SDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPF 859
             YD                 +P PP PA    +   +     S  SS      L  DP 
Sbjct: 774 --YD-----------------VPKPPVPA----VLARRTLSDISNASSSFGWLSLDGDPT 810

Query: 860 VDLASG-QVPLPPARRLPGENVKTNRTSQDYDQLPSCSDGSQAPARPPKPRPRRTAPEIH 918
            ++  G QVP  P +  P       R      +  SC  GS   A      P+       
Sbjct: 811 TNVTEGSQVPERPPKPFP-------RRINSERKAGSCQQGSGPAASAATASPQ------- 856

Query: 919 HRKPHGPEAALENVDAKIAKLMGEGYAFEEVKRALEIAQNNVEVARSILREF 970
                        + ++I  LM +GY+++++++AL IAQNN+E+A++ILREF
Sbjct: 857 -------------LSSEIENLMSQGYSYQDIQKALVIAQNNIEMAKNILREF 895


>gi|195927027 Cas-Br-M (murine) ecotropic retroviral transforming
           sequence c isoform 1 [Homo sapiens]
          Length = 474

 Score =  411 bits (1057), Expect = e-114
 Identities = 199/403 (49%), Positives = 271/403 (67%), Gaps = 10/403 (2%)

Query: 32  AVGPPKQAAADRRTVEKTWKLMDKVVRLCQNPKLQLKNSPPYILDILPDTYQHLRLILSK 91
           AV P  +   + R + +  +++ ++   C +P+L +  SPP + D+LP T Q LR +   
Sbjct: 4   AVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSV--SPPSLRDLLPRTAQLLREVAHS 61

Query: 92  Y---DDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLF-----KEGKERMYEEQSQDRRNL 143
                           ++  IY+ +L  KS++   L      +   + ++   S+ RR L
Sbjct: 62  RRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQL 121

Query: 144 TKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHE 203
            KL++IFSHM AE+ A+FP G++ G  +++TKA A  FWR+  G + ++PW  F   L  
Sbjct: 122 AKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLGT 181

Query: 204 VHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAF 263
            H +  G  A+AL++TIDLTC+ ++S+FEFD+FTRLFQPW ++L+NW  LAV HPGYMAF
Sbjct: 182 CHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMAF 241

Query: 264 LTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDG 323
           LTYDEV+ RLQ    KPGSYIFR SCTRLGQWAIGYV+ DG+ILQTIP NKPL Q L++G
Sbjct: 242 LTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLEG 301

Query: 324 SREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDV 383
            ++GFYLYPDG+++NPDLT L +  P   I V++EQ +LY  M STF+LCKICAE++KDV
Sbjct: 302 QKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKDV 361

Query: 384 KIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPIIVDPF 426
           KIEPCGHL+C+ CL AWQ SD Q CPFCRCEIKG E + +  F
Sbjct: 362 KIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQF 404


>gi|195927030 Cas-Br-M (murine) ecotropic retroviral transforming
           sequence c isoform 2 [Homo sapiens]
          Length = 428

 Score =  317 bits (811), Expect = 5e-86
 Identities = 165/403 (40%), Positives = 231/403 (57%), Gaps = 56/403 (13%)

Query: 32  AVGPPKQAAADRRTVEKTWKLMDKVVRLCQNPKLQLKNSPPYILDILPDTYQHLRLILSK 91
           AV P  +   + R + +  +++ ++   C +P+L +  SPP + D+LP T Q LR +   
Sbjct: 4   AVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSV--SPPSLRDLLPRTAQLLREVAHS 61

Query: 92  Y---DDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLF-----KEGKERMYEEQSQDRRNL 143
                           ++  IY+ +L  KS++   L      +   + ++   S+ RR L
Sbjct: 62  RRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQL 121

Query: 144 TKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHE 203
            KL++IFSHM AE+ A+FP G++ G  +++TKA A  FWR+  G + ++PW  F   L  
Sbjct: 122 AKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLGT 181

Query: 204 VHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAF 263
            H +  G  A+AL++TIDLTC+ ++S+FEFD+FTRLFQPW ++L+NW  LAV HPGYMAF
Sbjct: 182 CHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMAF 241

Query: 264 LTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDG 323
           LTYDEV+ RLQ    KPGSY                                        
Sbjct: 242 LTYDEVQERLQACRDKPGSY---------------------------------------- 261

Query: 324 SREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDV 383
                 LYPDG+++NPDLT L +  P   I V++EQ +LY  M STF+LCKICAE++KDV
Sbjct: 262 ------LYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKDV 315

Query: 384 KIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPIIVDPF 426
           KIEPCGHL+C+ CL AWQ SD Q CPFCRCEIKG E + +  F
Sbjct: 316 KIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQF 358


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 108/476 (22%), Positives = 158/476 (33%), Gaps = 88/476 (18%)

Query: 486  LAQRRKPQPDPLQIPHLSL-PPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPL 544
            L +  K + + +  P+ SL PP+ P+  ++          +P  + + SP        PL
Sbjct: 587  LEESSKARMESMNRPYTSLVPPLSPQPKIV----------TPYTASQPSP--------PL 628

Query: 545  PAPPPPLRDPPPPPPERPPPIPPDN------------------RLSRHIHHVESV--PSR 584
            P PPPP   PPPPPP  PPP+P  +                  RL     H  ++  P  
Sbjct: 629  PPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPT 688

Query: 585  DPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHRR 644
             P M  ++  P+ +   N +V         P P      +   +       P L     +
Sbjct: 689  PPVMQSQSVKPQILVPPNGVV-----PPPPPPPPPPTPGSAMAQLKPAPCAPSL----PQ 739

Query: 645  HDLPLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLP---------------SIKCTGP 689
               P    K+    H+       PP   PPPP+   LP               S K   P
Sbjct: 740  FSAPPPPLKIHQVQHITQV---APPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAP 796

Query: 690  LANSLSEKT-RDPVEEDDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHG 748
            +    +  T   PV     +   P+S+     S P+    V PP        C       
Sbjct: 797  VVTQAAPPTPTPPVPPAKKQPAFPASYIPP--SPPTPPVPVPPPTLPKQQSFC-AKPPPS 853

Query: 749  PSSEKKSNIPDLSIYLKGDVFDSASDPVPL--------PPARPPTRDNPKHGSSLNRTPS 800
            P S   S +  ++          A +  PL        P + P  +  PK   S    PS
Sbjct: 854  PLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPS 913

Query: 801  DYDLLIPPLGEDAFDALPPS----LPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPS 856
                  PP     F   PPS     PPPPPP      + S  PG  +  +S       P 
Sbjct: 914  PDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPP 973

Query: 857  DP----FVDLASGQVPLPPARRLPGENVKTNRTSQDYDQLPSCSDGSQAPARPPKP 908
             P     +  +SG     P R  P  +   ++ +   +      +    PA PPKP
Sbjct: 974  TPQRNSSIKSSSGAEHPEPKR--PSVDSLVSKFTPPAESGSPSKETLPPPAAPPKP 1027



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 110/484 (22%), Positives = 162/484 (33%), Gaps = 99/484 (20%)

Query: 477  PVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCM 536
            P  +PGS+ +AQ  KP P    +P  S PP P ++  +Q     +P   P   P  +P  
Sbjct: 717  PPPTPGSA-MAQL-KPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLP 774

Query: 537  VRKQDKPL---PAP----------------------PPPLRDP-------PPPPPERPPP 564
             +   KPL   PAP                      PP  + P       PP PP  P P
Sbjct: 775  PQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834

Query: 565  IPPDNRLSRHIHHVESVPSRDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSN 624
            +PP       +   +S  ++ PP PL       V    + +  +      P P    S  
Sbjct: 835  VPPPT-----LPKQQSFCAKPPPSPLS-----PVPSVVKQIASQF--PPPPTPPAMESQP 882

Query: 625  VNGRHSRVG--SDPVLMRKHR--RHDLPLEGAKVFSNGHLGSEEYDVPP----RLSPPPP 676
            +    + V   S P +  K +     +P+            S  +  PP       PPPP
Sbjct: 883  LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPP 942

Query: 677  VTTLLPSIKCTGPLANSLSE------KTRDPVEEDDDEYKIPS--SHP----------VS 718
              T  P+   +G      S+      K   P  + +   K  S   HP          VS
Sbjct: 943  PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVS 1002

Query: 719  LNSQPSHC-----HNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSAS 773
              + P+         + PP      G   L+G + P   ++  +   +  L G   DS  
Sbjct: 1003 KFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVV 1062

Query: 774  DPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAF---DALPPSLPPPPPPARH 830
            +  P PP+           S     P + +L +PP+   A    +  P      P P + 
Sbjct: 1063 E-FPSPPS----------DSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQW 1111

Query: 831  SLIEHSKPPGSSSRPSSGQDLFL----LPSDPFVDLASGQVPLPPARRL---PGENVKTN 883
            S +   K P   +RP       L    +   P +     QVP  P   L   PG     N
Sbjct: 1112 SKMSVKKAP-PPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLN 1170

Query: 884  RTSQ 887
            RT Q
Sbjct: 1171 RTLQ 1174



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 58/248 (23%), Positives = 82/248 (33%), Gaps = 42/248 (16%)

Query: 473  RQNSPVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKS 532
            +Q S    P  SPL+    P P  ++      PP P    +  + +   P      SP +
Sbjct: 842  KQQSFCAKPPPSPLS----PVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPA 897

Query: 533  SPCMVRKQDKPLPAPPPPLRDPPP-------PPPERPPPIPPDNRLSRHIHHVESVPSRD 585
                 + Q   +P P P    PPP       PPP  P P PP                  
Sbjct: 898  VKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPP------------------ 939

Query: 586  PPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHRRH 645
            PP P  A    D  G+      +    G  KP  T   N + + S     P    + +R 
Sbjct: 940  PPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHP----EPKRP 995

Query: 646  DLPLEGAKVFSNGHLGSEEYD-VPPRLSPPPPVTTLLPSIK--------CTGPLANSLSE 696
             +    +K       GS   + +PP  +PP P    L  +         C    A  LS 
Sbjct: 996  SVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSG 1055

Query: 697  KTRDPVEE 704
            + +D V E
Sbjct: 1056 RGKDSVVE 1063



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 32/117 (27%), Positives = 49/117 (41%), Gaps = 24/117 (20%)

Query: 471  TDRQNSPVTSPGSSPLAQRRKPQPDPL----------------QIPHLSLPPVPPRLDLI 514
            T ++NS + S   +   + ++P  D L                 +P  + PP P +L+L 
Sbjct: 974  TPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLS 1033

Query: 515  Q---KGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAPPPPL-RDPPPPPPERPPPIPP 567
                 G+++  C S      S     R +D  +  P PP   D PPPPPE   P+PP
Sbjct: 1034 GVNLPGVLQQGCVSAKAPVLSG----RGKDSVVEFPSPPSDSDFPPPPPETELPLPP 1086



 Score = 33.9 bits (76), Expect = 0.77
 Identities = 66/283 (23%), Positives = 97/283 (34%), Gaps = 69/283 (24%)

Query: 668 PPRLSPPPPVTTL-LPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPVSLNSQPSHC 726
           PP   PPPP+ +   PS     P+    S  TR          +  S H  +L   P+  
Sbjct: 640 PPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITR---------LQNASQHSGALFKPPT-- 688

Query: 727 HNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTR 786
               PPV                  + +S  P + +   G V      P P PP  PPT 
Sbjct: 689 ----PPVM-----------------QSQSVKPQILVPPNGVV------PPPPPPPPPPTP 721

Query: 787 DNPKHGSSLNRTPS-----DYDLLIPPLG----EDAFDALPPSLPPPPPPARHSLIEHSK 837
            +    + L   P       +    PPL     +      PP+ PPPPPP    L   + 
Sbjct: 722 GSAM--AQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPT-PPPPPPIPAPLPPQAP 778

Query: 838 PPGSSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARRLPGENVKTNRTSQDYDQLPSCSD 897
           P    + P+      + P        +   P+PPA++ P                P+ S 
Sbjct: 779 PKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPA--------------FPA-SY 823

Query: 898 GSQAPARPPKPRPRRTAPEIHH---RKPHGPEAALENVDAKIA 937
              +P  PP P P  T P+      + P  P + + +V  +IA
Sbjct: 824 IPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIA 866


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 121/486 (24%), Positives = 153/486 (31%), Gaps = 95/486 (19%)

Query: 476 SPVTSPGSSPLAQRRKPQPDPLQI-------PHLSLPPVPPRLDLIQKGIVRSPCGSPTG 528
           +P  S  + PL       P PLQ        PHL  PP P    L      ++P    T 
Sbjct: 525 TPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL------QAPPSPLTT 578

Query: 529 SPKSSPCMVRKQDKPLPAPPPPLRDPP----PPPP----ERPPPIPPDNRLSRHIHHVES 580
            P  +P  +     P P  PP L  PP    P PP      PPP  P       +    S
Sbjct: 579 PPPETPSSIAT---PPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS 635

Query: 581 VPSRDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMR 640
            P+  P  PL    P+     N L    L    SP P    S  V    S   S PV   
Sbjct: 636 PPASPPLSPLATPSPQ---APNALAVHLLQAPFSPPP----SPPVQAPFSPPASPPVSPS 688

Query: 641 KHRRHDLPLEGA------KVFSNGHLGSEEYDVPPRLSPPP---PVTTLLPSIKCTGPLA 691
                  P   A                     PP  +PPP   P   + PS   + P++
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS 748

Query: 692 NSLSEKTRDPVEEDDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSS 751
            S +   R P        ++P S P SL   P      KPP                P +
Sbjct: 749 PSATPPPRVPPLLAAPPLQVPPSPPASLPMSPL----AKPP----------------PQA 788

Query: 752 EKKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGE 811
                 P L               +P PPA  P +      +SL  +P    L  PP   
Sbjct: 789 PPALATPPL-------------QALPSPPASFPGQAPFSPSASLPMSP----LATPPPQA 831

Query: 812 DAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQVPLPP 871
               A P    PP PPA  +L    +P      P+ G D  +  S P + LA    P PP
Sbjct: 832 PPVLAAPLLQVPPSPPASPTLQAPRRP------PTPGPDTSV--SGPRLTLALAPGPPPP 883

Query: 872 ARRLP----------GENVKTNRTSQDYDQLPSCSDGSQAPARPPKPRPRRTAPEIHHRK 921
             R P          G +     T ++     S  +G  A + PP        P    R 
Sbjct: 884 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 943

Query: 922 PHGPEA 927
           P  P A
Sbjct: 944 PAPPLA 949



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 117/465 (25%), Positives = 153/465 (32%), Gaps = 133/465 (28%)

Query: 476 SPVTSPGSSPLAQRRKPQPDPLQIPHLSL--PPV-------PPRLDLIQKGIVRSPCGSP 526
           +P++S    PL  +    P  LQ P  SL  PP+       PP L      +      +P
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP 561

Query: 527 TGSPKSSPCMVRKQDKPLPAPPPPLRDPPP--------PPPERPPPI--PPDNRLSRHIH 576
              P  +PC       PL APP PL  PPP        PPP+ PP +  PP         
Sbjct: 562 ---PCPAPC-------PLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP--------- 602

Query: 577 HVESVPSRDPPM-PLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSD 635
            ++ +PS  PP+ PL    P+                    P   A   +    S   S 
Sbjct: 603 -LQGLPS--PPLSPLATPPPQ-------------------APPXLALPPLQAPPSPPASP 640

Query: 636 PVLMRKHRRHDLPLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLP-SIKCTGPLANSL 694
           P+          PL      +   L       P   SPPP      P S   + P++ S 
Sbjct: 641 PL---------SPLATPSPQAPNALAVHLLQAP--FSPPPSPPVQAPFSPPASPPVSPSA 689

Query: 695 SEKTRDPVEEDDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKK 754
           +  ++ P        ++P S P S    PS      PP                P +   
Sbjct: 690 TPPSQAPPSLAAPPLQVPPSPPASPPMSPS----ATPP----------------PQAPPP 729

Query: 755 SNIPDLSIYLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAF 814
              P L +              P PPA PP         S + TP      +PPL     
Sbjct: 730 LAAPPLQV-------------PPSPPASPP--------MSPSATPPP---RVPPL----- 760

Query: 815 DALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARR 874
            A PP   PP PPA   +   +KPP  +    +   L  LPS P      GQ P  P+  
Sbjct: 761 LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP--ASFPGQAPFSPSAS 818

Query: 875 LPGENVKTNRTSQ---------DYDQLPSCSDGSQAPARPPKPRP 910
           LP   + T                   P  S   QAP RPP P P
Sbjct: 819 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 863



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 103/440 (23%), Positives = 152/440 (34%), Gaps = 97/440 (22%)

Query: 476 SPVTSPGSS-------PLAQRRKPQPDPLQIPHLSLPPV-PPRLDLIQKGIVRSPCGSPT 527
           +P++SP  S       P A     QP P  +  L  P V PPR D           G  +
Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD------AAPALGPLS 300

Query: 528 GSPKSSPCMVRKQDKPLPAP-----PPPLRDPPPPPPERPPPI-PPDNRLSRHIHHVESV 581
            SP ++P     + +P+P P     P P   PP PP   P P+ PP       +  + S 
Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360

Query: 582 PSRDPPM--------PLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVG 633
           P+  P          P++A          Q+            P   A S++    S +G
Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS-LG 419

Query: 634 SDPVLMRKHRRHDLP--LEGAKVFSNGHLGSEEYDVPPRLSP------PPPVTTLLPSIK 685
           S P L   H    +      A + S     S   D PP  +P      PP  T+L P++ 
Sbjct: 420 S-PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAV- 477

Query: 686 CTGPLANSLSEKTRDPVEEDDDEYKIPSSHPV-SLNSQPSHCHN------VKPPVRSCDN 738
              PL++ L                  + HP+ +L+S  SH         + PP+ +  +
Sbjct: 478 --SPLSSPL------------------TIHPLQALSSLASHSPQAPLSSLIMPPLETQSS 517

Query: 739 --GHCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLN 796
                +       ++    N+P L+         +AS P+  P    P            
Sbjct: 518 LAPPSLQTPPASLTTPPLENLPSLA----PPPLQTASAPLTTPHLETPP----------- 562

Query: 797 RTPSDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPS 856
             P+   L  PP         P + PPP  P+  +      PP  +S P  G     LPS
Sbjct: 563 -CPAPCPLQAPP--------SPLTTPPPETPSSIATPPPQAPPALASPPLQG-----LPS 608

Query: 857 DPFVDLASGQVPLPPARRLP 876
            P   LA+     PP   LP
Sbjct: 609 PPLSPLATPPPQAPPXLALP 628



 Score = 35.0 bits (79), Expect = 0.35
 Identities = 111/490 (22%), Positives = 151/490 (30%), Gaps = 90/490 (18%)

Query: 479 TSPG--SSPLAQRRKPQPDPLQIPHLSLPPVP----------PRLDLIQKGIVRSPCGSP 526
           TSPG  SSP       +P PL    L +              P+   +  G  R   G  
Sbjct: 109 TSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT 168

Query: 527 TGSPKSSPCMVRKQ-----DKPLPAPPPPLRDPPPPPPERP-------------PPIPPD 568
            G+P  SP M R+      +  LP P P  R  P PP E P              P P  
Sbjct: 169 PGTP--SPAMARRSRAAGTEVGLPRPAPSAR--PRPPTEGPRKSVSSASEHSTTEPSPAA 224

Query: 569 NR-------LSRHIHHVESVPSRDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKP-GIT 620
            R       L R      S+ S   P+   A       GT +           PKP G+ 
Sbjct: 225 RRRPSAGGGLQRPASR--SLSSSATPLSSPARSGPSARGTPRAPA----HPSQPKPKGLQ 278

Query: 621 ASSNVNGRHSRVGSDPVLMRKHRRHDLPLEGAKVFSNGHLGSEEYDVPP----------R 670
           A         R  + P L         PL  + + +    G++   VPP           
Sbjct: 279 ALRPPQVTPPRKDAAPALG--------PLSSSPLATPSPSGTKARPVPPPDNAATPLPAT 330

Query: 671 LSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPVSLNSQPSHCHNVK 730
           L P PP+ T LP    +     SL      P          PS  P S+ + P       
Sbjct: 331 LPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP-------PSQAPPSMTTPPMQAPPSL 383

Query: 731 PPVRSCDNGHCMLNGT-HGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTRDNP 789
             +      H + + +   P S    +    +  L      +    + + P +  T+ + 
Sbjct: 384 QTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ--TQASL 441

Query: 790 KHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQ 849
              S    TP D   L  PL   A   L  SL P   P    L  H     SS    S Q
Sbjct: 442 TSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ 501

Query: 850 ----DLFLLPSDPFVDLASGQVPLPPARRLPGENVKTNRTSQDYDQLPSCSDGSQAPARP 905
                L + P +    LA   +  PPA          + T+   + LPS +      A  
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPA----------SLTTPPLENLPSLAPPPLQTASA 551

Query: 906 PKPRPRRTAP 915
           P   P    P
Sbjct: 552 PLTTPHLETP 561


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 124/514 (24%), Positives = 173/514 (33%), Gaps = 98/514 (19%)

Query: 425 PFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESLMMNRLANVRKCTDRQNSPVTSPGSS 484
           P +   E S   S+ D       D+D D         NR  +    + + N   +   SS
Sbjct: 126 PSEGEGESSDSRSVNDEGSSDPKDIDQD---------NRSTSPSIPSPQDNE--SDSDSS 174

Query: 485 PLAQRRKPQPDPLQIPH------LSLPPVPPRLDLIQKGIVRSPCG-SPTGSPKSSPCMV 537
              Q  + QP  LQ P        S PP  P+L     G   S     P GSP +S    
Sbjct: 175 AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPT--PGPTPSATAVPPQGSPTASQAPN 232

Query: 538 RKQDKPLPAPPPPLRDPPPPPPERPP---------PIPPDNRLSRHIHHVESVPSRDPPM 588
           + Q    P P   ++  P   P+RPP         P PP   L+       S PS   P 
Sbjct: 233 QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQ-PSAPSHAQP- 290

Query: 589 PLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHRRHDLP 648
           PL    P    G + L    LL    P          +   + +G+ P     H    LP
Sbjct: 291 PLHGQGPP---GPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 347

Query: 649 LEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDDDE 708
                  S   L S++   PPR  P PP    +P IK   P    + +       +    
Sbjct: 348 A------SQSALQSQQ---PPREQPLPPAPLAMPHIK--PPPTTPIPQLPAPQAHKHPPH 396

Query: 709 YKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDV 768
              PS  P S+N+      N+ PP             TH P S   ++ P L +      
Sbjct: 397 LSGPS--PFSMNA------NLPPPPALKPLSSL---STHHPPS---AHPPPLQLM----- 437

Query: 769 FDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPA 828
               S P+P  PA+PP         +L   P+ +    PP G          + P PP A
Sbjct: 438 --PQSQPLPSSPAQPP---GLTQSQNLPPPPASH----PPTGLH-------QVAPQPPFA 481

Query: 829 RHSLIEHSKPP------GSSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARRLPGENVKT 882
           +H  +    PP       S+S P +G      P       + G +    +  LP   +K 
Sbjct: 482 QHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK- 540

Query: 883 NRTSQDYDQLPSCSDGSQAPARPPKPRPRRTAPE 916
                         D ++ P  PP P PR  +PE
Sbjct: 541 ----------EEALDDAEEPESPPPP-PRSPSPE 563



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 43/166 (25%), Positives = 58/166 (34%), Gaps = 41/166 (24%)

Query: 778 LPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPP----PPPARHSL- 832
           L P RPP+   P H       PS +  L P  G     + P    PP     PP  HSL 
Sbjct: 252 LHPQRPPSPHPPPH-------PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQ 304

Query: 833 ----IEHSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQVPL--PPARRLPGENVK--TNR 884
               ++H  PP     P                 + GQ PL   PA   P  +++   ++
Sbjct: 305 AGPLLQHPGPPQPFGLPPQA--------------SQGQAPLGTSPAAAYPHTSLQLPASQ 350

Query: 885 TSQDYDQLPSCSDGSQAPAR-------PPKPRPRRTAPEIHHRKPH 923
           ++    Q P       AP         P  P P+  AP+ H   PH
Sbjct: 351 SALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPH 396



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 87/402 (21%), Positives = 122/402 (30%), Gaps = 85/402 (21%)

Query: 471 TDRQNSPVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSP 530
           T  QN P   P S P     +  P P    H  +P  PP +         +P   P G+ 
Sbjct: 454 TQSQNLP-PPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGP-GTS 511

Query: 531 KSSPC---------MVRKQDKPLP----------------APPPPLRDPPPPPP--ERPP 563
              PC         +      PLP                +PPPP R P P P   + P 
Sbjct: 512 AQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPS 571

Query: 564 PIPPDNRLSRHIHHVESVPSRDPPMPLEAWCPRDVFGTNQLVGCRLL---GEGSPKPGIT 620
                 R  +H+    +             C R       L G +L     E   K    
Sbjct: 572 HASQSARFYKHLDRGYNS------------CARTDLYFMPLAGSKLAKKREEAIEKAKRE 619

Query: 621 ASSNVNGRHSRVGSDPVLMRKHRRHDLPLE-GAKVFSNGH---LGSEEYDVPPRLSP--- 673
           A         R         + R  +   E  AK  S+ H   L   +   P  + P   
Sbjct: 620 AEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFE 679

Query: 674 PPPVT--TLLPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPVSLNSQPSH------ 725
           PPP T   + P I    P   +LSE  R  V    +      +HP  +   P+       
Sbjct: 680 PPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNR-----NHPFYMPLNPTDPLLAYH 734

Query: 726 ---CHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPPAR 782
               +NV P +R  +     +        E++    +L   +K        +  PL PA 
Sbjct: 735 MPGLYNVDPTIRERELREREIR-------EREIRERELRERMKPGFEVKPPELDPLHPAA 787

Query: 783 PPTRDNPKHGSSLNRTPSDYDLLIPP-LGEDAFDALPPSLPP 823
            P     +H +          L IPP  G   F +  P L P
Sbjct: 788 NPMEHFARHSA----------LTIPPTAGPHPFASFHPGLNP 819


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 124/514 (24%), Positives = 173/514 (33%), Gaps = 98/514 (19%)

Query: 425  PFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESLMMNRLANVRKCTDRQNSPVTSPGSS 484
            P +   E S   S+ D       D+D D         NR  +    + + N   +   SS
Sbjct: 680  PSEGEGESSDSRSVNDEGSSDPKDIDQD---------NRSTSPSIPSPQDNE--SDSDSS 728

Query: 485  PLAQRRKPQPDPLQIPH------LSLPPVPPRLDLIQKGIVRSPCG-SPTGSPKSSPCMV 537
               Q  + QP  LQ P        S PP  P+L     G   S     P GSP +S    
Sbjct: 729  AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPT--PGPTPSATAVPPQGSPTASQAPN 786

Query: 538  RKQDKPLPAPPPPLRDPPPPPPERPP---------PIPPDNRLSRHIHHVESVPSRDPPM 588
            + Q    P P   ++  P   P+RPP         P PP   L+       S PS   P 
Sbjct: 787  QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQ-PSAPSHAQP- 844

Query: 589  PLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHRRHDLP 648
            PL    P    G + L    LL    P          +   + +G+ P     H    LP
Sbjct: 845  PLHGQGPP---GPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 901

Query: 649  LEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDDDE 708
                   S   L S++   PPR  P PP    +P IK   P    + +       +    
Sbjct: 902  A------SQSALQSQQ---PPREQPLPPAPLAMPHIK--PPPTTPIPQLPAPQAHKHPPH 950

Query: 709  YKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDV 768
               PS  P S+N+      N+ PP             TH P S   ++ P L +      
Sbjct: 951  LSGPS--PFSMNA------NLPPPPALKPLSSL---STHHPPS---AHPPPLQLM----- 991

Query: 769  FDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPA 828
                S P+P  PA+PP         +L   P+ +    PP G          + P PP A
Sbjct: 992  --PQSQPLPSSPAQPP---GLTQSQNLPPPPASH----PPTGLH-------QVAPQPPFA 1035

Query: 829  RHSLIEHSKPP------GSSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARRLPGENVKT 882
            +H  +    PP       S+S P +G      P       + G +    +  LP   +K 
Sbjct: 1036 QHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK- 1094

Query: 883  NRTSQDYDQLPSCSDGSQAPARPPKPRPRRTAPE 916
                          D ++ P  PP P PR  +PE
Sbjct: 1095 ----------EEALDDAEEPESPPPP-PRSPSPE 1117



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 43/166 (25%), Positives = 58/166 (34%), Gaps = 41/166 (24%)

Query: 778 LPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPP----PPPARHSL- 832
           L P RPP+   P H       PS +  L P  G     + P    PP     PP  HSL 
Sbjct: 806 LHPQRPPSPHPPPH-------PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQ 858

Query: 833 ----IEHSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQVPL--PPARRLPGENVK--TNR 884
               ++H  PP     P                 + GQ PL   PA   P  +++   ++
Sbjct: 859 AGPLLQHPGPPQPFGLPPQA--------------SQGQAPLGTSPAAAYPHTSLQLPASQ 904

Query: 885 TSQDYDQLPSCSDGSQAPAR-------PPKPRPRRTAPEIHHRKPH 923
           ++    Q P       AP         P  P P+  AP+ H   PH
Sbjct: 905 SALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPH 950



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 87/402 (21%), Positives = 122/402 (30%), Gaps = 85/402 (21%)

Query: 471  TDRQNSPVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSP 530
            T  QN P   P S P     +  P P    H  +P  PP +         +P   P G+ 
Sbjct: 1008 TQSQNLP-PPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGP-GTS 1065

Query: 531  KSSPC---------MVRKQDKPLP----------------APPPPLRDPPPPPP--ERPP 563
               PC         +      PLP                +PPPP R P P P   + P 
Sbjct: 1066 AQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPS 1125

Query: 564  PIPPDNRLSRHIHHVESVPSRDPPMPLEAWCPRDVFGTNQLVGCRLL---GEGSPKPGIT 620
                  R  +H+    +             C R       L G +L     E   K    
Sbjct: 1126 HASQSARFYKHLDRGYNS------------CARTDLYFMPLAGSKLAKKREEAIEKAKRE 1173

Query: 621  ASSNVNGRHSRVGSDPVLMRKHRRHDLPLE-GAKVFSNGH---LGSEEYDVPPRLSP--- 673
            A         R         + R  +   E  AK  S+ H   L   +   P  + P   
Sbjct: 1174 AEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFE 1233

Query: 674  PPPVT--TLLPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPVSLNSQPSH------ 725
            PPP T   + P I    P   +LSE  R  V    +      +HP  +   P+       
Sbjct: 1234 PPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNR-----NHPFYMPLNPTDPLLAYH 1288

Query: 726  ---CHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPPAR 782
                +NV P +R  +     +        E++    +L   +K        +  PL PA 
Sbjct: 1289 MPGLYNVDPTIRERELREREIR-------EREIRERELRERMKPGFEVKPPELDPLHPAA 1341

Query: 783  PPTRDNPKHGSSLNRTPSDYDLLIPP-LGEDAFDALPPSLPP 823
             P     +H +          L IPP  G   F +  P L P
Sbjct: 1342 NPMEHFARHSA----------LTIPPTAGPHPFASFHPGLNP 1373


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 124/514 (24%), Positives = 173/514 (33%), Gaps = 98/514 (19%)

Query: 425  PFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESLMMNRLANVRKCTDRQNSPVTSPGSS 484
            P +   E S   S+ D       D+D D         NR  +    + + N   +   SS
Sbjct: 680  PSEGEGESSDSRSVNDEGSSDPKDIDQD---------NRSTSPSIPSPQDNE--SDSDSS 728

Query: 485  PLAQRRKPQPDPLQIPH------LSLPPVPPRLDLIQKGIVRSPCG-SPTGSPKSSPCMV 537
               Q  + QP  LQ P        S PP  P+L     G   S     P GSP +S    
Sbjct: 729  AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPT--PGPTPSATAVPPQGSPTASQAPN 786

Query: 538  RKQDKPLPAPPPPLRDPPPPPPERPP---------PIPPDNRLSRHIHHVESVPSRDPPM 588
            + Q    P P   ++  P   P+RPP         P PP   L+       S PS   P 
Sbjct: 787  QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQ-PSAPSHAQP- 844

Query: 589  PLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHRRHDLP 648
            PL    P    G + L    LL    P          +   + +G+ P     H    LP
Sbjct: 845  PLHGQGPP---GPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 901

Query: 649  LEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDDDE 708
                   S   L S++   PPR  P PP    +P IK   P    + +       +    
Sbjct: 902  A------SQSALQSQQ---PPREQPLPPAPLAMPHIK--PPPTTPIPQLPAPQAHKHPPH 950

Query: 709  YKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDV 768
               PS  P S+N+      N+ PP             TH P S   ++ P L +      
Sbjct: 951  LSGPS--PFSMNA------NLPPPPALKPLSSL---STHHPPS---AHPPPLQLM----- 991

Query: 769  FDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPA 828
                S P+P  PA+PP         +L   P+ +    PP G          + P PP A
Sbjct: 992  --PQSQPLPSSPAQPP---GLTQSQNLPPPPASH----PPTGLH-------QVAPQPPFA 1035

Query: 829  RHSLIEHSKPP------GSSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARRLPGENVKT 882
            +H  +    PP       S+S P +G      P       + G +    +  LP   +K 
Sbjct: 1036 QHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK- 1094

Query: 883  NRTSQDYDQLPSCSDGSQAPARPPKPRPRRTAPE 916
                          D ++ P  PP P PR  +PE
Sbjct: 1095 ----------EEALDDAEEPESPPPP-PRSPSPE 1117



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 43/166 (25%), Positives = 58/166 (34%), Gaps = 41/166 (24%)

Query: 778 LPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPP----PPPARHSL- 832
           L P RPP+   P H       PS +  L P  G     + P    PP     PP  HSL 
Sbjct: 806 LHPQRPPSPHPPPH-------PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQ 858

Query: 833 ----IEHSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQVPL--PPARRLPGENVK--TNR 884
               ++H  PP     P                 + GQ PL   PA   P  +++   ++
Sbjct: 859 AGPLLQHPGPPQPFGLPPQA--------------SQGQAPLGTSPAAAYPHTSLQLPASQ 904

Query: 885 TSQDYDQLPSCSDGSQAPAR-------PPKPRPRRTAPEIHHRKPH 923
           ++    Q P       AP         P  P P+  AP+ H   PH
Sbjct: 905 SALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPH 950



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 87/402 (21%), Positives = 122/402 (30%), Gaps = 85/402 (21%)

Query: 471  TDRQNSPVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSP 530
            T  QN P   P S P     +  P P    H  +P  PP +         +P   P G+ 
Sbjct: 1008 TQSQNLP-PPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGP-GTS 1065

Query: 531  KSSPC---------MVRKQDKPLP----------------APPPPLRDPPPPPP--ERPP 563
               PC         +      PLP                +PPPP R P P P   + P 
Sbjct: 1066 AQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPS 1125

Query: 564  PIPPDNRLSRHIHHVESVPSRDPPMPLEAWCPRDVFGTNQLVGCRLL---GEGSPKPGIT 620
                  R  +H+    +             C R       L G +L     E   K    
Sbjct: 1126 HASQSARFYKHLDRGYNS------------CARTDLYFMPLAGSKLAKKREEAIEKAKRE 1173

Query: 621  ASSNVNGRHSRVGSDPVLMRKHRRHDLPLE-GAKVFSNGH---LGSEEYDVPPRLSP--- 673
            A         R         + R  +   E  AK  S+ H   L   +   P  + P   
Sbjct: 1174 AEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFE 1233

Query: 674  PPPVT--TLLPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPVSLNSQPSH------ 725
            PPP T   + P I    P   +LSE  R  V    +      +HP  +   P+       
Sbjct: 1234 PPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNR-----NHPFYMPLNPTDPLLAYH 1288

Query: 726  ---CHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPPAR 782
                +NV P +R  +     +        E++    +L   +K        +  PL PA 
Sbjct: 1289 MPGLYNVDPTIRERELREREIR-------EREIRERELRERMKPGFEVKPPELDPLHPAA 1341

Query: 783  PPTRDNPKHGSSLNRTPSDYDLLIPP-LGEDAFDALPPSLPP 823
             P     +H +          L IPP  G   F +  P L P
Sbjct: 1342 NPMEHFARHSA----------LTIPPTAGPHPFASFHPGLNP 1373


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 113/497 (22%), Positives = 158/497 (31%), Gaps = 88/497 (17%)

Query: 505 PPV-----PPRLDLIQKGIVRSPCGSPTGSP---KSSPCMVRKQDKP--LPAPPPPLRDP 554
           PPV     PP +  +    +  P G    SP   +   C   +   P  LP PPPPL  P
Sbjct: 195 PPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPP 254

Query: 555 PPPPPERPPPIP-------------------------PDNRLSRHIHHVESVPSRDPPMP 589
           PPPPP  PPP+P                         P+ + S      E   S   P P
Sbjct: 255 PPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYP 314

Query: 590 LEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHRRHDLPL 649
             A         ++LV     G G   PG  +   +       GSD   +R+ R     +
Sbjct: 315 YPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPP-GSD---LRESR-----V 365

Query: 650 EGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDDDEY 709
           + +++ S+    +    VP   S PP +     S   +      L     +P     D Y
Sbjct: 366 QRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHY 425

Query: 710 KIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDL------SIY 763
           + P+             H+ + P          L+   GPSS      P L        +
Sbjct: 426 QTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAW 485

Query: 764 LKGDVFDSASDPV------------PLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGE 811
           LKG    +A +              P  PA PP              P     L PP   
Sbjct: 486 LKGPACRAAREDGEILEELFFGTEGPPRPAPPPL-------------PHREGFLGPPASR 532

Query: 812 DAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQVPLPP 871
            +        PP PP    S    S    S S  SS       P  P++  +   +P PP
Sbjct: 533 FSVGTQDSHTPPTPPTPTTS----SSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPP 588

Query: 872 ARRLPGENVKTNRTSQDYDQLP-----SCSDGSQAP-ARPPKPRPRRTAPEIHHRKPHGP 925
           +   P +N +          LP     SC   +     RP  PRPR + P+     P  P
Sbjct: 589 S---PAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPP 645

Query: 926 EAALENVDAKIAKLMGE 942
              L      +   +GE
Sbjct: 646 PGPLSKAPQPVPPGVGE 662



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 58/222 (26%), Positives = 86/222 (38%), Gaps = 29/222 (13%)

Query: 442 FGMPMLDLDD--DDDREESLMMNRLANVRKCTDRQNSPVTSPGSSPLAQRRKPQPDPLQI 499
           F  P   L+D  ++  E  ++ + LAN+ K  D                   PQP PL+ 
Sbjct: 671 FDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA--PQP-PLKE 727

Query: 500 PHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPA--PPPPL-RDPPP 556
           P  SL    P               + T +  ++     ++ KP PA  PPPPL + PPP
Sbjct: 728 PFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPP 787

Query: 557 PPPERPPPIPPD-NRLSRHIHHV------------ESVPSRDPPMPLEAWCPRDVFGTNQ 603
             P+ PPP PP    L + +  V             +V +R  P+P   + P    G   
Sbjct: 788 SQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATA 847

Query: 604 L--VGCRLLGEGSPKPGITASSNVN------GRHSRVGSDPV 637
           L         +GSP+P  ++SS  +       R  R G +PV
Sbjct: 848 LPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPV 889



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 107/458 (23%), Positives = 142/458 (31%), Gaps = 115/458 (25%)

Query: 492 PQPDPLQIPHLSLPPVP-----PRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDK---- 542
           P P P   P    PP+P     P   L + G+  +  G   G  +       +Q++    
Sbjct: 250 PLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSL 309

Query: 543 ----PLPAPPPPLRDP--------PPPPPERPP------------PIPPDNRLSRHIHH- 577
               P PAP      P        PP P  RPP            P   D R SR     
Sbjct: 310 PHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSR 369

Query: 578 -------------VESVPSRDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSN 624
                        V   PSR P +P           +N   G R +    P PGI  + +
Sbjct: 370 MDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSN--TGLRGV---EPNPGIPGADH 424

Query: 625 VN------GRHSRVGSDPVLMRKHRRHDLPLEGAKVFSNGHLGSEEYDVPPRLS--PPPP 676
                     H R+G      RK      P  GA   +  HL      +PP  S  PPPP
Sbjct: 425 YQTPALEVSHHGRLGPSAHSSRK------PFLGAPA-ATPHLS-----LPPGPSSPPPPP 472

Query: 677 VTTLL----PSIKCTGPLANSLSE----------------KTRDPVEEDDDEYKIPSSHP 716
              LL    P     GP   +  E                +   P     + +  P +  
Sbjct: 473 CPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASR 532

Query: 717 VSLNSQPSHCHNVKP-PVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASDP 775
            S+ +Q SH     P P  S  N +   +G+H  S     + P    YL   +     DP
Sbjct: 533 FSVGTQDSHTPPTPPTPTTSSSNSN---SGSHSSSPAGPVSFPPPP-YLARSI-----DP 583

Query: 776 VPLPPARPPTRDNPK------------HGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPP 823
           +P PP+      +P               S    T   +     P    +F   P  + P
Sbjct: 584 LPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTP-EVGP 642

Query: 824 PPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVD 861
            PPP   S      PPG    P+ G  LF  P  P  D
Sbjct: 643 GPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLED 680



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 109/489 (22%), Positives = 154/489 (31%), Gaps = 133/489 (27%)

Query: 482 GSSPLAQRRKPQPDPLQIPHLSLPPVP--------PRLDLIQKGIVRSPCGSPTGSPKSS 533
           G S  + R+     P   PHLSLPP P        PRL       +R P   P    K  
Sbjct: 439 GPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL-------LRPP--PPPAWLKGP 489

Query: 534 PCMVRKQDKPLP-----APPPPLRDPPPPPPERPPPI-PPDNRLSRHIHHVESVPSRDPP 587
            C   ++D  +          P R  PPP P R   + PP +R S     V +  S  PP
Sbjct: 490 ACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFS-----VGTQDSHTPP 544

Query: 588 MPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHRRHDL 647
            P                         P P  ++S++ +G HS   + PV          
Sbjct: 545 TP-------------------------PTPTTSSSNSNSGSHSSSPAGPVSF-------- 571

Query: 648 PLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTR--DPVEED 705
                                    PPPP             LA S+    R   P +  
Sbjct: 572 -------------------------PPPPY------------LARSIDPLPRPPSPAQNP 594

Query: 706 DDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLK 765
            D   +P +  +   + PS CH                  T G     +S  P +S    
Sbjct: 595 QDPPLVPLTLALP-PAPPSSCH----------------QNTSGSFRRPESPRPRVSFPKT 637

Query: 766 GDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFD--ALPPSLPP 823
            +V      P P P ++ P    P  G    R P  +D    PL ED F+  A    LP 
Sbjct: 638 PEV---GPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPL-EDQFEEPAEFKILPD 693

Query: 824 PPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVD-LASGQVPLP----PARRLPGE 878
                   L E  +      +  +G    + P  P  +  AS Q P P    P    P  
Sbjct: 694 GLANIMKMLDESIRKEEEQQQHEAG----VAPQPPLKEPFASLQSPFPTDTAPTTTAPAV 749

Query: 879 NVKTNRTSQDYDQLPSCSDGSQAPARPPKPRPRRTAPEIHHRKPHGPEAALENVDAKIAK 938
            V T  T+          +    PA PP P   +  P    + P  P  +  ++   +A 
Sbjct: 750 AVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLAS 809

Query: 939 LM-GEGYAF 946
           ++ G+ Y +
Sbjct: 810 VLEGQKYCY 818



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 36/123 (29%), Positives = 45/123 (36%), Gaps = 38/123 (30%)

Query: 481 PGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQ 540
           P   P +  + PQ  PL    L+LPP PP           S C   T          R+ 
Sbjct: 583 PLPRPPSPAQNPQDPPLVPLTLALPPAPP-----------SSCHQNTSG------SFRRP 625

Query: 541 DKPLPA---PPPPLRDPPPPP---PERPPPIPPDNRLSRHIHHVESVPSRD------PPM 588
           + P P    P  P   P PPP    + P P+PP          V  +P+R       PP 
Sbjct: 626 ESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPG---------VGELPARGPRLFDFPPT 676

Query: 589 PLE 591
           PLE
Sbjct: 677 PLE 679



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 65/253 (25%), Positives = 88/253 (34%), Gaps = 49/253 (19%)

Query: 493  QPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMV----------RKQDK 542
            +P PL     S  P      L       S  GSP  S  SS              R  ++
Sbjct: 828  RPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEE 887

Query: 543  PLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHH-----VESV--PSRDPPMPLEAWCP 595
            P+P P  P +   PPPP   PP   ++ +   I       VE V   + DP  P++   P
Sbjct: 888  PVPGPMTPTQ---PPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEP 944

Query: 596  RDVFGTNQLV---------GCRLLGEGSPKPGITASSNVNGRHSR-----VGSDPVLMRK 641
             D  GT +L+         G      GS K         + RH R     VG  P   R 
Sbjct: 945  AD-SGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRA 1003

Query: 642  HRRHDLPLE-GAKVFSNGHLGSEEYDVPPRLSP-------------PPPVTTLLPSIKCT 687
              +  +P E   +V  N  L SEE     +  P             P P +   PS + T
Sbjct: 1004 KAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPT 1063

Query: 688  GPLANSLSEKTRD 700
             P A+   +K R+
Sbjct: 1064 PPSASVPGKKARE 1076


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 106/412 (25%), Positives = 144/412 (34%), Gaps = 71/412 (17%)

Query: 543 PLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVESVPSRDPPMPLEAWCPRDVFGTN 602
           P+P PPPP   PPPPP   PPP PP    +  +    S   R  P    A       GT 
Sbjct: 2   PVPPPPPPPLPPPPPPLGAPPPPPPS---APPVSTDTSSLRRADPKGRSALLADIQQGTR 58

Query: 603 QLVGCRLLGEGSPKPGITASSNVNG---RHSRVGSDPVLMRKHRRHDLPL---EGAKVFS 656
                ++    +P+   +  +N  G    ++R  S P  +        P+    G +  +
Sbjct: 59  LRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVA 118

Query: 657 NGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHP 716
            G  G      P   +P P     LP+   +GPL    S +  +  E        P    
Sbjct: 119 GGKTGQG----PGSRAPSP----RLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPN 170

Query: 717 VSL---NSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSAS 773
           V      + P     + PP+ S       L    GP +  K N+P              +
Sbjct: 171 VPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLT--KGNLP------------VVA 216

Query: 774 DPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPP---PPPPARH 830
            PVP  P  PP    P        TP      +PP    +  A+ P L P   PP P   
Sbjct: 217 PPVPCAPPPPPPPPPP--------TPPP----LPPASVLSDKAVKPQLAPLHLPPIPPPL 264

Query: 831 SLIEHSKPPGSSSRPSS-GQDLF--LLPSDPFVDLAS----GQVPLPPARRLPGENVKTN 883
            L+     PG  + P+S  QD      P  P    AS      +P PP   LPG     N
Sbjct: 265 PLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPP---LPG----VN 317

Query: 884 RTSQDYDQLPSCSDGSQAP-------ARPPKPRPRRTAPEIHHRKPHGPEAA 928
            +S+    LP  S   QAP       A P  P P  + P +  +K HG   A
Sbjct: 318 SSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFL-QKKRHGRPGA 368



 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 37/105 (35%), Positives = 49/105 (46%), Gaps = 7/105 (6%)

Query: 487 AQRRKPQPDPLQIPHLSLPPVPPRLD--LIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPL 544
           A+   P+P+    P  + PP PP L   L     +++P  SP G        V     P+
Sbjct: 162 ARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAP--PV 219

Query: 545 PAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVESVPSRDPPMP 589
           P  PPP   PPPPPP  PPP+PP + LS      +  P   PP+P
Sbjct: 220 PCAPPP---PPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIP 261



 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 39/109 (35%), Positives = 49/109 (44%), Gaps = 30/109 (27%)

Query: 476 SPVTSPGSSPLAQRR-KPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSP 534
           +P   P +S L+ +  KPQ  PL      LPP+PP L L+       PCG P    K+ P
Sbjct: 233 TPPPLPPASVLSDKAVKPQLAPLH-----LPPIPPPLPLLP------PCGYP--GLKAEP 279

Query: 535 CMVRKQDKPLPAPPPPLRD----------PPPPPP------ERPPPIPP 567
               +  +  PAPPPPL            P PP P      E PPP+PP
Sbjct: 280 ASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPP 328


>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 100/371 (26%), Positives = 131/371 (35%), Gaps = 98/371 (26%)

Query: 502 LSLPPVPPR-LDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPPE 560
           L +PP PP       + I   P GSP  SP S+           P PPP L +PPPPP  
Sbjct: 137 LLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTA----------PPPPPLLLEPPPPPSM 186

Query: 561 RPPPIPPDNRLS-RHIHHVESVPS--------------RDPPMPLEAWCPRDVFGTNQLV 605
            PPP P    LS  H     S+P+                PP P+ A  P     +   V
Sbjct: 187 APPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAP-PAPASPHTV 245

Query: 606 GCRLLGEGSPKPGIT---ASSNVNGRHSRV--GSDPVLMRKHRRHDLPLEGAKVFSN--G 658
           G RL     P  G+T   +   +NGR +     S P       R     +G+ +  N   
Sbjct: 246 GTRLF----PPGGVTKWKSDVALNGRQAEATRASPP-------RSPAEPKGSALGPNPEP 294

Query: 659 HLG-SEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPV 717
           HL     + VPP   P P  T+ +P           + E    P +E+    K PS  P+
Sbjct: 295 HLTFPRSFKVPP---PTPVRTSSIP-----------VQEAQEAPRKEEGATKKAPSRLPL 340

Query: 718 --SLNSQP-SHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASD 774
             S + +P S  +  + P   C  G         P   +  +  D          + A  
Sbjct: 341 PPSFHIRPASQVYPDRAPEPDCP-GELKATAPASPRLGQSQSQAD----------ERAGT 389

Query: 775 PVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPP--PPARHSL 832
           P P PP  PP                      PPL   A   LPP+ PP P    A H  
Sbjct: 390 PPPAPPLPPPA---------------------PPLPPPA-PPLPPAAPPLPCAQKAAHPP 427

Query: 833 IEHSKPPGSSS 843
              +K P SSS
Sbjct: 428 AGFTKTPKSSS 438



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 86/397 (21%), Positives = 136/397 (34%), Gaps = 77/397 (19%)

Query: 479 TSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQK------GIVRSP-CGSPTGSPK 531
           T P + PL     P   PL  P   LPP  P L   QK      G  ++P   SP   PK
Sbjct: 389 TPPPAPPL----PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPK 444

Query: 532 SSP-------------------------------CMVRKQDKPLPAPPPPLRDPPPPPPE 560
            +P                               C  R++D+ L   P P   P     +
Sbjct: 445 PNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGK 504

Query: 561 RPPPIPPDNRLSRHIHHVESVPSRDPP--MPLEAWCPRDVFGTNQLVGCRL-----LGEG 613
           + P +P    L        S+P++D P  +P ++     +  T       L     + + 
Sbjct: 505 KGPRLPEKETLL-------SLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQD 557

Query: 614 SPKPGITASSNVNGRHSRVGSDPVLMRKHRRHDLP----LEGAKVFSNGHLGSEEYDVPP 669
           SP P +      N   +R+ S      K     LP    LEG ++  NG    ++   P 
Sbjct: 558 SPTPSVRQIR--NELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENG-ADDDKLSKPV 614

Query: 670 RLSPPPPVTTLLP--SIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPVSLNSQPSHCH 727
             + PP  TTLLP  S++    L  ++  K          E  IP    +   + P    
Sbjct: 615 AKNLPPQSTTLLPTTSLQPKAMLGPAIPPKA-------TPEPAIPPKATLWPATPPKATL 667

Query: 728 NVKPPVRSCDNGHCMLNGTHGPS-SEKKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTR 786
               P+++       L  T GP+ +   + +P  +  L  +     +     P ++  + 
Sbjct: 668 GPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVST 727

Query: 787 DNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPP 823
            +   G     +PS+   L P  G  +  A PP   P
Sbjct: 728 PSQARGEG---SPSEATRL-PTQGARSSAAFPPKTSP 760



 Score = 37.0 bits (84), Expect = 0.091
 Identities = 31/100 (31%), Positives = 39/100 (39%), Gaps = 6/100 (6%)

Query: 472 DRQNSPVTSPGSSPLAQRRKPQPDPLQIPHLS--LPPVPPRLDLIQKGIVRSPCGSPTGS 529
           + Q +P    G++  A  R P P    I   S   P   P  D   +    +P     G 
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQ 378

Query: 530 PKSSPCMVRKQDKPLPAPP-PPLRDP-PPPPPERPPPIPP 567
            +S      +   P PAPP PP   P PPP P  PP  PP
Sbjct: 379 SQSQAD--ERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP 416



 Score = 35.0 bits (79), Expect = 0.35
 Identities = 41/132 (31%), Positives = 46/132 (34%), Gaps = 29/132 (21%)

Query: 799 PSDY--DLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQ------D 850
           P  Y  DLLIPP         PP  P P PP      + S+PPG S  PS          
Sbjct: 130 PGQYGQDLLIPP---------PPPGPAPGPPQ-----DISEPPGGSPLPSPPSTAPPPPP 175

Query: 851 LFLLPSDPFVDLASGQVPLPPARRL--PGENVKTNRTSQDYDQLPSCSD-GSQAPARPPK 907
           L L P  P     S   P PP      P   + +       D +P        AP  PP 
Sbjct: 176 LLLEPPPP----PSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPV 231

Query: 908 PRPRRTAPEIHH 919
           P P   AP   H
Sbjct: 232 PAPAPPAPASPH 243



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 7/76 (9%)

Query: 775 PVPLPPARPPTRD--NPKHGSSLNRTPSDYDLLIPPLGEDAFDALPP----SLPPPPPPA 828
           P  + P  PP  +  +P H  S    P+  D  IPP    AF A PP    +  PP P +
Sbjct: 183 PPSMAPPPPPVLEALSPPHTLSSPSIPTPPDF-IPPAPPLAFLAPPPPPVPAPAPPAPAS 241

Query: 829 RHSLIEHSKPPGSSSR 844
            H++     PPG  ++
Sbjct: 242 PHTVGTRLFPPGGVTK 257


>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 100/371 (26%), Positives = 131/371 (35%), Gaps = 98/371 (26%)

Query: 502 LSLPPVPPR-LDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPPE 560
           L +PP PP       + I   P GSP  SP S+           P PPP L +PPPPP  
Sbjct: 137 LLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTA----------PPPPPLLLEPPPPPSM 186

Query: 561 RPPPIPPDNRLS-RHIHHVESVPS--------------RDPPMPLEAWCPRDVFGTNQLV 605
            PPP P    LS  H     S+P+                PP P+ A  P     +   V
Sbjct: 187 APPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAP-PAPASPHTV 245

Query: 606 GCRLLGEGSPKPGIT---ASSNVNGRHSRV--GSDPVLMRKHRRHDLPLEGAKVFSN--G 658
           G RL     P  G+T   +   +NGR +     S P       R     +G+ +  N   
Sbjct: 246 GTRLF----PPGGVTKWKSDVALNGRQAEATRASPP-------RSPAEPKGSALGPNPEP 294

Query: 659 HLG-SEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPV 717
           HL     + VPP   P P  T+ +P           + E    P +E+    K PS  P+
Sbjct: 295 HLTFPRSFKVPP---PTPVRTSSIP-----------VQEAQEAPRKEEGATKKAPSRLPL 340

Query: 718 --SLNSQP-SHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASD 774
             S + +P S  +  + P   C  G         P   +  +  D          + A  
Sbjct: 341 PPSFHIRPASQVYPDRAPEPDCP-GELKATAPASPRLGQSQSQAD----------ERAGT 389

Query: 775 PVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPP--PPARHSL 832
           P P PP  PP                      PPL   A   LPP+ PP P    A H  
Sbjct: 390 PPPAPPLPPPA---------------------PPLPPPA-PPLPPAAPPLPCAQKAAHPP 427

Query: 833 IEHSKPPGSSS 843
              +K P SSS
Sbjct: 428 AGFTKTPKSSS 438



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 86/397 (21%), Positives = 136/397 (34%), Gaps = 77/397 (19%)

Query: 479 TSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQK------GIVRSP-CGSPTGSPK 531
           T P + PL     P   PL  P   LPP  P L   QK      G  ++P   SP   PK
Sbjct: 389 TPPPAPPL----PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPK 444

Query: 532 SSP-------------------------------CMVRKQDKPLPAPPPPLRDPPPPPPE 560
            +P                               C  R++D+ L   P P   P     +
Sbjct: 445 PNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGK 504

Query: 561 RPPPIPPDNRLSRHIHHVESVPSRDPP--MPLEAWCPRDVFGTNQLVGCRL-----LGEG 613
           + P +P    L        S+P++D P  +P ++     +  T       L     + + 
Sbjct: 505 KGPRLPEKETLL-------SLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQD 557

Query: 614 SPKPGITASSNVNGRHSRVGSDPVLMRKHRRHDLP----LEGAKVFSNGHLGSEEYDVPP 669
           SP P +      N   +R+ S      K     LP    LEG ++  NG    ++   P 
Sbjct: 558 SPTPSVRQIR--NELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENG-ADDDKLSKPV 614

Query: 670 RLSPPPPVTTLLP--SIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPVSLNSQPSHCH 727
             + PP  TTLLP  S++    L  ++  K          E  IP    +   + P    
Sbjct: 615 AKNLPPQSTTLLPTTSLQPKAMLGPAIPPKA-------TPEPAIPPKATLWPATPPKATL 667

Query: 728 NVKPPVRSCDNGHCMLNGTHGPS-SEKKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTR 786
               P+++       L  T GP+ +   + +P  +  L  +     +     P ++  + 
Sbjct: 668 GPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVST 727

Query: 787 DNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPP 823
            +   G     +PS+   L P  G  +  A PP   P
Sbjct: 728 PSQARGEG---SPSEATRL-PTQGARSSAAFPPKTSP 760



 Score = 37.0 bits (84), Expect = 0.091
 Identities = 31/100 (31%), Positives = 39/100 (39%), Gaps = 6/100 (6%)

Query: 472 DRQNSPVTSPGSSPLAQRRKPQPDPLQIPHLS--LPPVPPRLDLIQKGIVRSPCGSPTGS 529
           + Q +P    G++  A  R P P    I   S   P   P  D   +    +P     G 
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQ 378

Query: 530 PKSSPCMVRKQDKPLPAPP-PPLRDP-PPPPPERPPPIPP 567
            +S      +   P PAPP PP   P PPP P  PP  PP
Sbjct: 379 SQSQAD--ERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP 416



 Score = 35.0 bits (79), Expect = 0.35
 Identities = 41/132 (31%), Positives = 46/132 (34%), Gaps = 29/132 (21%)

Query: 799 PSDY--DLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQ------D 850
           P  Y  DLLIPP         PP  P P PP      + S+PPG S  PS          
Sbjct: 130 PGQYGQDLLIPP---------PPPGPAPGPPQ-----DISEPPGGSPLPSPPSTAPPPPP 175

Query: 851 LFLLPSDPFVDLASGQVPLPPARRL--PGENVKTNRTSQDYDQLPSCSD-GSQAPARPPK 907
           L L P  P     S   P PP      P   + +       D +P        AP  PP 
Sbjct: 176 LLLEPPPP----PSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPV 231

Query: 908 PRPRRTAPEIHH 919
           P P   AP   H
Sbjct: 232 PAPAPPAPASPH 243



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 7/76 (9%)

Query: 775 PVPLPPARPPTRD--NPKHGSSLNRTPSDYDLLIPPLGEDAFDALPP----SLPPPPPPA 828
           P  + P  PP  +  +P H  S    P+  D  IPP    AF A PP    +  PP P +
Sbjct: 183 PPSMAPPPPPVLEALSPPHTLSSPSIPTPPDF-IPPAPPLAFLAPPPPPVPAPAPPAPAS 241

Query: 829 RHSLIEHSKPPGSSSR 844
            H++     PPG  ++
Sbjct: 242 PHTVGTRLFPPGGVTK 257


>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
           sapiens]
          Length = 1188

 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 100/371 (26%), Positives = 131/371 (35%), Gaps = 98/371 (26%)

Query: 502 LSLPPVPPR-LDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPPE 560
           L +PP PP       + I   P GSP  SP S+           P PPP L +PPPPP  
Sbjct: 137 LLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTA----------PPPPPLLLEPPPPPSM 186

Query: 561 RPPPIPPDNRLS-RHIHHVESVPS--------------RDPPMPLEAWCPRDVFGTNQLV 605
            PPP P    LS  H     S+P+                PP P+ A  P     +   V
Sbjct: 187 APPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAP-PAPASPHTV 245

Query: 606 GCRLLGEGSPKPGIT---ASSNVNGRHSRV--GSDPVLMRKHRRHDLPLEGAKVFSN--G 658
           G RL     P  G+T   +   +NGR +     S P       R     +G+ +  N   
Sbjct: 246 GTRLF----PPGGVTKWKSDVALNGRQAEATRASPP-------RSPAEPKGSALGPNPEP 294

Query: 659 HLG-SEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPV 717
           HL     + VPP   P P  T+ +P           + E    P +E+    K PS  P+
Sbjct: 295 HLTFPRSFKVPP---PTPVRTSSIP-----------VQEAQEAPRKEEGATKKAPSRLPL 340

Query: 718 --SLNSQP-SHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASD 774
             S + +P S  +  + P   C  G         P   +  +  D          + A  
Sbjct: 341 PPSFHIRPASQVYPDRAPEPDCP-GELKATAPASPRLGQSQSQAD----------ERAGT 389

Query: 775 PVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPP--PPARHSL 832
           P P PP  PP                      PPL   A   LPP+ PP P    A H  
Sbjct: 390 PPPAPPLPPPA---------------------PPLPPPA-PPLPPAAPPLPCAQKAAHPP 427

Query: 833 IEHSKPPGSSS 843
              +K P SSS
Sbjct: 428 AGFTKTPKSSS 438



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 86/397 (21%), Positives = 136/397 (34%), Gaps = 77/397 (19%)

Query: 479 TSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQK------GIVRSP-CGSPTGSPK 531
           T P + PL     P   PL  P   LPP  P L   QK      G  ++P   SP   PK
Sbjct: 389 TPPPAPPL----PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPK 444

Query: 532 SSP-------------------------------CMVRKQDKPLPAPPPPLRDPPPPPPE 560
            +P                               C  R++D+ L   P P   P     +
Sbjct: 445 PNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGK 504

Query: 561 RPPPIPPDNRLSRHIHHVESVPSRDPP--MPLEAWCPRDVFGTNQLVGCRL-----LGEG 613
           + P +P    L        S+P++D P  +P ++     +  T       L     + + 
Sbjct: 505 KGPRLPEKETLL-------SLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQD 557

Query: 614 SPKPGITASSNVNGRHSRVGSDPVLMRKHRRHDLP----LEGAKVFSNGHLGSEEYDVPP 669
           SP P +      N   +R+ S      K     LP    LEG ++  NG    ++   P 
Sbjct: 558 SPTPSVRQIR--NELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENG-ADDDKLSKPV 614

Query: 670 RLSPPPPVTTLLP--SIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPVSLNSQPSHCH 727
             + PP  TTLLP  S++    L  ++  K          E  IP    +   + P    
Sbjct: 615 AKNLPPQSTTLLPTTSLQPKAMLGPAIPPKA-------TPEPAIPPKATLWPATPPKATL 667

Query: 728 NVKPPVRSCDNGHCMLNGTHGPS-SEKKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTR 786
               P+++       L  T GP+ +   + +P  +  L  +     +     P ++  + 
Sbjct: 668 GPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVST 727

Query: 787 DNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPP 823
            +   G     +PS+   L P  G  +  A PP   P
Sbjct: 728 PSQARGEG---SPSEATRL-PTQGARSSAAFPPKTSP 760



 Score = 37.0 bits (84), Expect = 0.091
 Identities = 31/100 (31%), Positives = 39/100 (39%), Gaps = 6/100 (6%)

Query: 472 DRQNSPVTSPGSSPLAQRRKPQPDPLQIPHLS--LPPVPPRLDLIQKGIVRSPCGSPTGS 529
           + Q +P    G++  A  R P P    I   S   P   P  D   +    +P     G 
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQ 378

Query: 530 PKSSPCMVRKQDKPLPAPP-PPLRDP-PPPPPERPPPIPP 567
            +S      +   P PAPP PP   P PPP P  PP  PP
Sbjct: 379 SQSQAD--ERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP 416



 Score = 35.0 bits (79), Expect = 0.35
 Identities = 41/132 (31%), Positives = 46/132 (34%), Gaps = 29/132 (21%)

Query: 799 PSDY--DLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQ------D 850
           P  Y  DLLIPP         PP  P P PP      + S+PPG S  PS          
Sbjct: 130 PGQYGQDLLIPP---------PPPGPAPGPPQ-----DISEPPGGSPLPSPPSTAPPPPP 175

Query: 851 LFLLPSDPFVDLASGQVPLPPARRL--PGENVKTNRTSQDYDQLPSCSD-GSQAPARPPK 907
           L L P  P     S   P PP      P   + +       D +P        AP  PP 
Sbjct: 176 LLLEPPPP----PSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPV 231

Query: 908 PRPRRTAPEIHH 919
           P P   AP   H
Sbjct: 232 PAPAPPAPASPH 243



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 7/76 (9%)

Query: 775 PVPLPPARPPTRD--NPKHGSSLNRTPSDYDLLIPPLGEDAFDALPP----SLPPPPPPA 828
           P  + P  PP  +  +P H  S    P+  D  IPP    AF A PP    +  PP P +
Sbjct: 183 PPSMAPPPPPVLEALSPPHTLSSPSIPTPPDF-IPPAPPLAFLAPPPPPVPAPAPPAPAS 241

Query: 829 RHSLIEHSKPPGSSSR 844
            H++     PPG  ++
Sbjct: 242 PHTVGTRLFPPGGVTK 257


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 96/405 (23%), Positives = 145/405 (35%), Gaps = 53/405 (13%)

Query: 522 PCGSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPPERPP-PIPPDNRLSRHIHHVES 580
           P GS   +   SP M RKQ+  L +  PP +   PP P RP  P    +R +      + 
Sbjct: 67  PKGSVPPAAAESPSMHRKQE--LDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQK 124

Query: 581 VPSRDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPG----ITASSNVNGRHSRVGSDP 636
           +P R P           +  +      +   + S  PG    + A S V+   ++     
Sbjct: 125 LPGRSPSTI-------SLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFD 177

Query: 637 VLMRKHRRHDLPLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSE 696
           ++       +   +  KV      G  E  + P L   PP     P  K  GP       
Sbjct: 178 LISDSEASQEETTKKQKVVQKEQ-GKPEGIIKPPLQQQPPK----PIPKQQGP------- 225

Query: 697 KTRDPVEEDDDEYKIPSSHPVSLNSQPSHCHN-VKPPVRSCDNGHCML---NGTHGPSSE 752
             RDP+++D     I S  P  + SQP      ++ P ++    H  L        P ++
Sbjct: 226 -GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTK 284

Query: 753 KKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTRDNPKHGSSL---NRTPSDYDLLIPPL 809
           +   +   S+  K  +   +  P+  P    P    P H  S     + P+    L  PL
Sbjct: 285 QADIVRGESV--KPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPL 342

Query: 810 GEDAFDALPPSLPP--PPPPARHSLIEHSKPPG---SSSRPSSGQ-DLFLLPSDPFVDLA 863
            +      PP  PP    PPA+   +  +KPP     S +PSS Q     L   P V   
Sbjct: 343 AQQPGTVKPPVQPPGTTKPPAQP--LGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKT 400

Query: 864 SGQVPLPPARRLPGENVKTNRTSQDYDQLPSCSDGSQAPARPPKP 908
             Q P P   + P + V T +             G Q+PA+ P P
Sbjct: 401 PAQQPGP--AKPPTQQVGTPKPLAQ-------QPGLQSPAKAPGP 436



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 26/62 (41%), Positives = 32/62 (51%), Gaps = 11/62 (17%)

Query: 515  QKGIVRSPCGSPTGSP---------KSSPCMVRKQDKPLPAPPPPLRDPPPPPPERPPPI 565
            +K   + P GSP+ S          +SS   +  Q  P P PPPP   PPPPPP  PPP+
Sbjct: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPP--PPPPPPPPPPPPL 2427

Query: 566  PP 567
            PP
Sbjct: 2428 PP 2429



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 103/475 (21%), Positives = 161/475 (33%), Gaps = 109/475 (22%)

Query: 474  QNSPVTSPG----SSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPC--GSPT 527
            + +PVT+      SSP  Q+  P+ D      LS  P P +       +V+ P   GSP+
Sbjct: 662  KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK----PPPLVKQPTLHGSPS 717

Query: 528  GSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVESVPSRDPP 587
               K  P     +   L  P PP ++P  P  +   P+  D             P +   
Sbjct: 718  AKAKQPP-----EADSLSKPAPP-KEPSVPSEQDKAPVADDK------------PKQ--- 756

Query: 588  MPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHR-RHD 646
                   P+ V  T  LV        + KP I  SS V  +     + P+     +    
Sbjct: 757  -------PKMVKPTTDLVSS---SSATTKPDIP-SSKVQSQAEEKTTPPLKTDSAKPSQS 805

Query: 647  LPLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDD 706
             P  G KV          +D   +  P P   + +  I   GP + S  +K  DPV++ +
Sbjct: 806  FPPTGEKV--------SPFD--SKAIPRPASDSKI--ISHPGPSSESKGQKQVDPVQKKE 853

Query: 707  DEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKG 766
            +  K  +      +++P    +  PP      G  +      P  +++S    L++   G
Sbjct: 854  EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNL---G 910

Query: 767  DVFDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPP 826
             + D A    P  P    T      G+S+    S+   LI   G+      P S   P  
Sbjct: 911  SITD-APKSQPTTPQETVTGKLFGFGASIFSQASN---LISTAGQPG----PHSQSGPGA 962

Query: 827  PARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARRLP---------- 876
            P + +    S+PP S   P S                +GQ P  PA+ +P          
Sbjct: 963  PMKQAPAP-SQPPTSQGPPKS----------------TGQAPPAPAKSIPVKKETKAPAA 1005

Query: 877  ------GENVKTNRTSQDYDQLPSCSDGSQAPARPPK----------PRPRRTAP 915
                   E   T + ++   + P   D     A P K          P+P  T P
Sbjct: 1006 EKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060



 Score = 35.0 bits (79), Expect = 0.35
 Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 10/96 (10%)

Query: 476 SPVTSPGSSPLAQRRKPQPDPL-QIPHLSLP---PVPPRLDLIQKGIVRSPCGSPTGSPK 531
           +P   PG +    ++   P PL Q P L  P   P P +  + Q G  + P      + +
Sbjct: 400 TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP------AQQ 453

Query: 532 SSPCMVRKQDKPLPAPPPPLRDPPPPPPERPPPIPP 567
           + P     Q      PP  L  P  PPP++P P  P
Sbjct: 454 AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKP 489



 Score = 33.9 bits (76), Expect = 0.77
 Identities = 94/422 (22%), Positives = 128/422 (30%), Gaps = 70/422 (16%)

Query: 531 KSSPCMVRKQDKPLPAPPPPLRDPPPPP------PERPPPIPPDNRLSRHIHHVESVPSR 584
           K    + ++Q KP     PPL+  PP P      P R P        S      E + S+
Sbjct: 191 KKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQ 250

Query: 585 DP------------PMPLEAWCP--RDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHS 630
            P            P    A  P  RD           + GE S KP + + S    +  
Sbjct: 251 PPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGE-SVKPSLPSPSKPPIQQP 309

Query: 631 RVGSDPVLMRKHRRHDLPLEGAKVFSNGHLGSEEYDVPPRLSPP--PPVTTLLPSIKCTG 688
             G  P     H +   P           L       P  + PP  PP TT  P+     
Sbjct: 310 TPGKPPAQQPGHEKSQ-PGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA----Q 364

Query: 689 PLANSLSEKTRDPVEEDDDEYKIPS--SHPVSLNSQPSHCHN-VKPPVRSCDNGHCMLNG 745
           PL  +     +   E+   E   P   + P  +   P+      KPP +          G
Sbjct: 365 PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQV--------G 416

Query: 746 THGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLL 805
           T  P +++    P L    K      A  P   P  +P     P   +   +T +     
Sbjct: 417 TPKPLAQQ----PGLQSPAK------APGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP 466

Query: 806 IPPLGEDAFDALPPSLPP----PPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVD 861
             P  +    A PP   P    PPP    S    S+ PGS+  P         P  P   
Sbjct: 467 TKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP---------PQQPGPA 517

Query: 862 LASGQVP--LPPARRLPG------ENVKTNRTSQDYDQLPSCSDGSQAPARPPKPRPRRT 913
             S Q P    P  + PG      +     + S      P    GS  P +PP   P   
Sbjct: 518 KPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAK 577

Query: 914 AP 915
            P
Sbjct: 578 QP 579



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 100/471 (21%), Positives = 151/471 (32%), Gaps = 47/471 (9%)

Query: 471 TDRQNSPVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSP 530
           TD    P+    S P  ++          P L  P  PP    IQ+     P     G  
Sbjct: 267 TDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPP----IQQPTPGKPPAQQPGHE 322

Query: 531 KSSPCMVRKQ------DKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVES-VPS 583
           KS P   +         KPL   P  ++ P  PP    PP  P            S  PS
Sbjct: 323 KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS 382

Query: 584 RDPPMPLEAWCPRDVFGT-NQLVGCR---LLGEGSPKPGITASSNVNGRHSRVGSDPVLM 639
            + P P     P  V  T  Q  G         G+PKP +     +       G     +
Sbjct: 383 SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP-LAQQPGLQSPAKAPGPTKTPV 441

Query: 640 RKHRRHDLPLEGAKVFSNGHLGSEEY--DVPPRLSPPPPVTTLLPSIKCTGPLANSLSEK 697
           ++     +P + A     G   +++     PP   P P      P  +  GP      + 
Sbjct: 442 QQPGPGKIPAQQA---GPGKTSAQQTGPTKPPSQLPGP----AKPPPQQPGPAKPPPQQP 494

Query: 698 -TRDPVEEDDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSN 756
            +  P  +     K P   P      P    + KPP +          G+  PS+++ S 
Sbjct: 495 GSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ--------PGSAKPSAQQPSP 546

Query: 757 I-PDLSIYLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTP--SDYDLLIPPLGEDA 813
             P      K      +  P+  P   P  +  P  G      P  +  +LL+    +  
Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN 606

Query: 814 FDALPP------SLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQV 867
           F+          SL    P    + ++         + + G DL  +PS P   L +   
Sbjct: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT--A 664

Query: 868 PLPPARRLPGENVKTNRTSQDYDQLPSCSDGSQAPARPPKPRPRRTAPEIH 918
           P+     +   + +  +TS   D  P   D S+AP  P KP P    P +H
Sbjct: 665 PVTTTSAVSKSSPQPQQTSPKKDAAPK-QDLSKAP-EPKKPPPLVKQPTLH 713



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 23/85 (27%), Positives = 29/85 (34%), Gaps = 10/85 (11%)

Query: 763  YLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTPS-DYDLLIPPLGEDAFDALPPSL 821
            +  G+ F        LP   P     P       R+ S D     PP         PP  
Sbjct: 2361 FTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPP---------PPPP 2411

Query: 822  PPPPPPARHSLIEHSKPPGSSSRPS 846
            PPPPPP          PP +S +P+
Sbjct: 2412 PPPPPPPPPPPPPPPLPPPTSPKPT 2436


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 96/405 (23%), Positives = 145/405 (35%), Gaps = 53/405 (13%)

Query: 522 PCGSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPPERPP-PIPPDNRLSRHIHHVES 580
           P GS   +   SP M RKQ+  L +  PP +   PP P RP  P    +R +      + 
Sbjct: 67  PKGSVPPAAAESPSMHRKQE--LDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQK 124

Query: 581 VPSRDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPG----ITASSNVNGRHSRVGSDP 636
           +P R P           +  +      +   + S  PG    + A S V+   ++     
Sbjct: 125 LPGRSPSTI-------SLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFD 177

Query: 637 VLMRKHRRHDLPLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSE 696
           ++       +   +  KV      G  E  + P L   PP     P  K  GP       
Sbjct: 178 LISDSEASQEETTKKQKVVQKEQ-GKPEGIIKPPLQQQPPK----PIPKQQGP------- 225

Query: 697 KTRDPVEEDDDEYKIPSSHPVSLNSQPSHCHN-VKPPVRSCDNGHCML---NGTHGPSSE 752
             RDP+++D     I S  P  + SQP      ++ P ++    H  L        P ++
Sbjct: 226 -GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTK 284

Query: 753 KKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTRDNPKHGSSL---NRTPSDYDLLIPPL 809
           +   +   S+  K  +   +  P+  P    P    P H  S     + P+    L  PL
Sbjct: 285 QADIVRGESV--KPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPL 342

Query: 810 GEDAFDALPPSLPP--PPPPARHSLIEHSKPPG---SSSRPSSGQ-DLFLLPSDPFVDLA 863
            +      PP  PP    PPA+   +  +KPP     S +PSS Q     L   P V   
Sbjct: 343 AQQPGTVKPPVQPPGTTKPPAQP--LGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKT 400

Query: 864 SGQVPLPPARRLPGENVKTNRTSQDYDQLPSCSDGSQAPARPPKP 908
             Q P P   + P + V T +             G Q+PA+ P P
Sbjct: 401 PAQQPGP--AKPPTQQVGTPKPLAQ-------QPGLQSPAKAPGP 436



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 26/62 (41%), Positives = 32/62 (51%), Gaps = 11/62 (17%)

Query: 515  QKGIVRSPCGSPTGSP---------KSSPCMVRKQDKPLPAPPPPLRDPPPPPPERPPPI 565
            +K   + P GSP+ S          +SS   +  Q  P P PPPP   PPPPPP  PPP+
Sbjct: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPP--PPPPPPPPPPPPL 2427

Query: 566  PP 567
            PP
Sbjct: 2428 PP 2429



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 103/475 (21%), Positives = 161/475 (33%), Gaps = 109/475 (22%)

Query: 474  QNSPVTSPG----SSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPC--GSPT 527
            + +PVT+      SSP  Q+  P+ D      LS  P P +       +V+ P   GSP+
Sbjct: 662  KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK----PPPLVKQPTLHGSPS 717

Query: 528  GSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVESVPSRDPP 587
               K  P     +   L  P PP ++P  P  +   P+  D             P +   
Sbjct: 718  AKAKQPP-----EADSLSKPAPP-KEPSVPSEQDKAPVADDK------------PKQ--- 756

Query: 588  MPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHR-RHD 646
                   P+ V  T  LV        + KP I  SS V  +     + P+     +    
Sbjct: 757  -------PKMVKPTTDLVSS---SSATTKPDIP-SSKVQSQAEEKTTPPLKTDSAKPSQS 805

Query: 647  LPLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDD 706
             P  G KV          +D   +  P P   + +  I   GP + S  +K  DPV++ +
Sbjct: 806  FPPTGEKV--------SPFD--SKAIPRPASDSKI--ISHPGPSSESKGQKQVDPVQKKE 853

Query: 707  DEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKG 766
            +  K  +      +++P    +  PP      G  +      P  +++S    L++   G
Sbjct: 854  EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNL---G 910

Query: 767  DVFDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPP 826
             + D A    P  P    T      G+S+    S+   LI   G+      P S   P  
Sbjct: 911  SITD-APKSQPTTPQETVTGKLFGFGASIFSQASN---LISTAGQPG----PHSQSGPGA 962

Query: 827  PARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARRLP---------- 876
            P + +    S+PP S   P S                +GQ P  PA+ +P          
Sbjct: 963  PMKQAPAP-SQPPTSQGPPKS----------------TGQAPPAPAKSIPVKKETKAPAA 1005

Query: 877  ------GENVKTNRTSQDYDQLPSCSDGSQAPARPPK----------PRPRRTAP 915
                   E   T + ++   + P   D     A P K          P+P  T P
Sbjct: 1006 EKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060



 Score = 35.0 bits (79), Expect = 0.35
 Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 10/96 (10%)

Query: 476 SPVTSPGSSPLAQRRKPQPDPL-QIPHLSLP---PVPPRLDLIQKGIVRSPCGSPTGSPK 531
           +P   PG +    ++   P PL Q P L  P   P P +  + Q G  + P      + +
Sbjct: 400 TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP------AQQ 453

Query: 532 SSPCMVRKQDKPLPAPPPPLRDPPPPPPERPPPIPP 567
           + P     Q      PP  L  P  PPP++P P  P
Sbjct: 454 AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKP 489



 Score = 33.9 bits (76), Expect = 0.77
 Identities = 94/422 (22%), Positives = 128/422 (30%), Gaps = 70/422 (16%)

Query: 531 KSSPCMVRKQDKPLPAPPPPLRDPPPPP------PERPPPIPPDNRLSRHIHHVESVPSR 584
           K    + ++Q KP     PPL+  PP P      P R P        S      E + S+
Sbjct: 191 KKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQ 250

Query: 585 DP------------PMPLEAWCP--RDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHS 630
            P            P    A  P  RD           + GE S KP + + S    +  
Sbjct: 251 PPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGE-SVKPSLPSPSKPPIQQP 309

Query: 631 RVGSDPVLMRKHRRHDLPLEGAKVFSNGHLGSEEYDVPPRLSPP--PPVTTLLPSIKCTG 688
             G  P     H +   P           L       P  + PP  PP TT  P+     
Sbjct: 310 TPGKPPAQQPGHEKSQ-PGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA----Q 364

Query: 689 PLANSLSEKTRDPVEEDDDEYKIPS--SHPVSLNSQPSHCHN-VKPPVRSCDNGHCMLNG 745
           PL  +     +   E+   E   P   + P  +   P+      KPP +          G
Sbjct: 365 PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQV--------G 416

Query: 746 THGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLL 805
           T  P +++    P L    K      A  P   P  +P     P   +   +T +     
Sbjct: 417 TPKPLAQQ----PGLQSPAK------APGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP 466

Query: 806 IPPLGEDAFDALPPSLPP----PPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVD 861
             P  +    A PP   P    PPP    S    S+ PGS+  P         P  P   
Sbjct: 467 TKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP---------PQQPGPA 517

Query: 862 LASGQVP--LPPARRLPG------ENVKTNRTSQDYDQLPSCSDGSQAPARPPKPRPRRT 913
             S Q P    P  + PG      +     + S      P    GS  P +PP   P   
Sbjct: 518 KPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAK 577

Query: 914 AP 915
            P
Sbjct: 578 QP 579



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 100/471 (21%), Positives = 151/471 (32%), Gaps = 47/471 (9%)

Query: 471 TDRQNSPVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSP 530
           TD    P+    S P  ++          P L  P  PP    IQ+     P     G  
Sbjct: 267 TDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPP----IQQPTPGKPPAQQPGHE 322

Query: 531 KSSPCMVRKQ------DKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVES-VPS 583
           KS P   +         KPL   P  ++ P  PP    PP  P            S  PS
Sbjct: 323 KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS 382

Query: 584 RDPPMPLEAWCPRDVFGT-NQLVGCR---LLGEGSPKPGITASSNVNGRHSRVGSDPVLM 639
            + P P     P  V  T  Q  G         G+PKP +     +       G     +
Sbjct: 383 SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP-LAQQPGLQSPAKAPGPTKTPV 441

Query: 640 RKHRRHDLPLEGAKVFSNGHLGSEEY--DVPPRLSPPPPVTTLLPSIKCTGPLANSLSEK 697
           ++     +P + A     G   +++     PP   P P      P  +  GP      + 
Sbjct: 442 QQPGPGKIPAQQA---GPGKTSAQQTGPTKPPSQLPGP----AKPPPQQPGPAKPPPQQP 494

Query: 698 -TRDPVEEDDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSN 756
            +  P  +     K P   P      P    + KPP +          G+  PS+++ S 
Sbjct: 495 GSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ--------PGSAKPSAQQPSP 546

Query: 757 I-PDLSIYLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTP--SDYDLLIPPLGEDA 813
             P      K      +  P+  P   P  +  P  G      P  +  +LL+    +  
Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN 606

Query: 814 FDALPP------SLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQV 867
           F+          SL    P    + ++         + + G DL  +PS P   L +   
Sbjct: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT--A 664

Query: 868 PLPPARRLPGENVKTNRTSQDYDQLPSCSDGSQAPARPPKPRPRRTAPEIH 918
           P+     +   + +  +TS   D  P   D S+AP  P KP P    P +H
Sbjct: 665 PVTTTSAVSKSSPQPQQTSPKKDAAPK-QDLSKAP-EPKKPPPLVKQPTLH 713



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 23/85 (27%), Positives = 29/85 (34%), Gaps = 10/85 (11%)

Query: 763  YLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTPS-DYDLLIPPLGEDAFDALPPSL 821
            +  G+ F        LP   P     P       R+ S D     PP         PP  
Sbjct: 2361 FTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPP---------PPPP 2411

Query: 822  PPPPPPARHSLIEHSKPPGSSSRPS 846
            PPPPPP          PP +S +P+
Sbjct: 2412 PPPPPPPPPPPPPPPLPPPTSPKPT 2436


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 43/124 (34%), Positives = 54/124 (43%), Gaps = 13/124 (10%)

Query: 450 DDDDDREESLMMNRLANVRKCTDRQNSPVTSPGSSPLAQRRKPQ---PDPLQIPHLSLPP 506
           DD+DD ++S    +     K  +  +S  TS  SS   Q+  PQ   P  +Q P +  PP
Sbjct: 356 DDEDDSDDSEAEKQSQKQHK--EESHSDGTSTASSQ--QQAPPQSVPPSQIQAPPMPGPP 411

Query: 507 V---PPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPPERPP 563
               PP   L   G    P G P G P  +P  +R    P    P P   PP PPP RPP
Sbjct: 412 PLGPPPAPPLRPPG---PPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPP 468

Query: 564 PIPP 567
             PP
Sbjct: 469 GPPP 472



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 38/130 (29%), Positives = 53/130 (40%), Gaps = 16/130 (12%)

Query: 450 DDDDDREESLMMNRLANVRKCTDRQNSPVTSPGSSPLAQRRKPQPDPLQIPHLSLPP--- 506
           DDD+D  +     + +  +   +  +   ++  S   A  +   P  +Q P +  PP   
Sbjct: 355 DDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLG 414

Query: 507 VPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKP---------LPAPPPPLRDPPPP 557
            PP   L   G    P G P G P  +P  +R    P         LP  PPP R PP P
Sbjct: 415 PPPAPPLRPPG---PPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGR-PPGP 470

Query: 558 PPERPPPIPP 567
           PP  PP +PP
Sbjct: 471 PPGPPPGLPP 480



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 34/102 (33%), Positives = 34/102 (33%), Gaps = 24/102 (23%)

Query: 775 PVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIE 834
           P P PP RPP    P  G      P     L PP        LP  LPP PPP R     
Sbjct: 415 PPPAPPLRPP---GPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGR----- 466

Query: 835 HSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARRLP 876
              PPG    P  G             L  G  P  P  RLP
Sbjct: 467 ---PPGPPPGPPPG-------------LPPGPPPRGPPPRLP 492



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 32/93 (34%), Positives = 36/93 (38%), Gaps = 9/93 (9%)

Query: 481 PGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQ 540
           PG  P    R P P P   P   LPP PP     +    R P  +P G P   P M+R  
Sbjct: 460 PGPPP---GRPPGPPPGPPP--GLPPGPPP----RGPPPRLPPPAPPGIPPPRPGMMRPP 510

Query: 541 DKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSR 573
             P   P PP   PP P P       P N + R
Sbjct: 511 LVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQR 543



 Score = 34.3 bits (77), Expect = 0.59
 Identities = 26/73 (35%), Positives = 32/73 (43%), Gaps = 14/73 (19%)

Query: 775 PVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIE 834
           P  LPP  PP    P+ G  + R P     L+PPLG       PP L PP P     ++ 
Sbjct: 488 PPRLPPPAPPGIPPPRPG--MMRPP-----LVPPLG-----PAPPGLFPPAPLPNPGVL- 534

Query: 835 HSKPPGSSSRPSS 847
            S PP    RP +
Sbjct: 535 -SAPPNLIQRPKA 546



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 34/109 (31%), Positives = 37/109 (33%), Gaps = 23/109 (21%)

Query: 818 PPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQVP--LPPARRL 875
           PP  PPP PP R        PPG    P  G   FL P  P +    G +P  LPP    
Sbjct: 411 PPLGPPPAPPLRPPGPPTGLPPG----PPPGAPPFLRP--PGMPGLRGPLPRLLPPGPP- 463

Query: 876 PGENVKTNRTSQDYDQLPSCSDGSQAPARPPKPRPRRTAPEIHHRKPHG 924
           PG               P        P  PP P PR   P +    P G
Sbjct: 464 PGR--------------PPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPG 498


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 116/502 (23%), Positives = 161/502 (32%), Gaps = 110/502 (21%)

Query: 442  FGMPMLDLDDDDDREESLMMNRLANVRKCTDRQNSPVTSPGSSPLAQRRKPQPDPLQIPH 501
            FG  +  +D +      ++       R   D +  P              PQP P  + H
Sbjct: 610  FGYKLAGMDPEKPGTPIVLRRAQPRARSSNDARRPPA-------------PQPAPRTLSH 656

Query: 502  LSL---PPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPP 558
             S    PPVPPR           P   P  +P  SP +      P PA P       PPP
Sbjct: 657  WSALLSPPVPPR----------PPSSGPPPAPPLSPAL---SGLPRPASPYGSLRRHPPP 703

Query: 559  PERPPPIPPDNRLSRHIHHVESVPSRDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPG 618
               P  +PP  + S     VE  P+  P +P +                 LL    P+P 
Sbjct: 704  WAAPAHVPPAPQASWWA-FVEP-PAVSPEVPPD-----------------LLAFPGPRPS 744

Query: 619  ITASSNVNGRHSRVGSDPVLMRKHRRHDLPLEGAKVFSNGHLGSEEYDVPPRLSPPPPVT 678
               S          G+ P   R+     L      + S+  LG   Y  P  L+PP P  
Sbjct: 745  FRGSRRRGAAFGFPGASPRASRRRAWSPLASPQPSLRSSPGLG---YCSP--LAPPSPQL 799

Query: 679  TLLPSIKCTGPLANSLSEKTRDP--VEEDDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSC 736
            +L      TGP         R P  ++E     +         +  P       PP+  C
Sbjct: 800  SLR-----TGPFQPPFLPPARRPRSLQESPAPRRAAGRLGPPGSPLPGSPRPPSPPLGLC 854

Query: 737  DNGHCMLNGTHGP---SSEKKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTRD---NPK 790
                      H P   S    S +P     L      +    V LP  RPP       P 
Sbjct: 855  ----------HSPRRSSLNLPSRLPHTWRRLSEPPTRAVKPQVRLPFHRPPRAGAWRAPL 904

Query: 791  HGSSLNRTPSDYDL--LIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSG 848
                  R P D +    +PPL       +PP+  PP P           P G+ SR    
Sbjct: 905  EHRESPREPEDSETPWTVPPLAPSWDVDMPPTQRPPSP----------WPGGAGSRRGFS 954

Query: 849  QDLFLLPSDPFVDLASGQVPLP------PARRL------------PGENVKTNRTSQDYD 890
            +    +P +PF+ L  G VP P      PA  +            PG+  K+   + +  
Sbjct: 955  RPP-PVPENPFLQLL-GPVPSPTLQPEDPAADMTRVFLGRHHEPGPGQLTKSAGPTPEKP 1012

Query: 891  QLPSCSDGSQAPA--RPPKPRP 910
            +  +     Q PA  +PP P P
Sbjct: 1013 EEEATLGDPQLPAETKPPTPAP 1034


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 48/142 (33%), Positives = 58/142 (40%), Gaps = 22/142 (15%)

Query: 477 PVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPT--GSPKSSP 534
           P  SP S  LA   +P P     P    PP  P L   Q+    +P  +P   GSP+  P
Sbjct: 522 PTGSP-SPDLAPAAEPAPGAAPPP----PPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPP 576

Query: 535 CMVRKQDKPLPAPPPPLRD------PPPPPPERPPPIPPDNRLSRHIHHV-ESVPSRDP- 586
                 D P P PPPP         PPPPPP  PPP  P + L R    +   V ++ P 
Sbjct: 577 APPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSELGPGVKAKKPI 636

Query: 587 ----PMPLEAWC---PRDVFGT 601
                MPL  W    P  + GT
Sbjct: 637 QTKFRMPLLNWVALKPSQITGT 658



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 33/95 (34%), Positives = 39/95 (41%), Gaps = 12/95 (12%)

Query: 476 SPVTSPGSSPLAQRRKPQPDPLQ---IPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKS 532
           SP  +P + P      P P PL     P  + P  PP+   +         GSP   P +
Sbjct: 527 SPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLP--------GSPE-PPPA 577

Query: 533 SPCMVRKQDKPLPAPPPPLRDPPPPPPERPPPIPP 567
            P        P P PPPP  D P PPP  PPP PP
Sbjct: 578 PPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPP 612



 Score = 38.9 bits (89), Expect = 0.024
 Identities = 43/161 (26%), Positives = 52/161 (32%), Gaps = 38/161 (23%)

Query: 776 VPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIEH 835
           +P+  A P   D P  G        D    + P  E A    P + PPPPPP        
Sbjct: 504 LPVAVATPSGGDAPTPGVPTGSPSPD----LAPAAEPA----PGAAPPPPPPLPGLPSPQ 555

Query: 836 SKPPGSSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARRLPGENVKTNRTSQDYDQLPSC 895
             PP   S P     L   P  P      G +P PP    P                P  
Sbjct: 556 EAPP---SAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPP----------------PPG 596

Query: 896 SDGSQAPARPPKPRPRRTAPEIHHRKPHGPEAALENVDAKI 936
           +DG   P  PP P P           P GP  AL   D+++
Sbjct: 597 TDGPVPPPPPPPPPP-----------PGGPPDALGRRDSEL 626



 Score = 34.7 bits (78), Expect = 0.45
 Identities = 22/48 (45%), Positives = 23/48 (47%), Gaps = 8/48 (16%)

Query: 524 GSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPP----PPPPERPPPIPP 567
           G PTGSP S       +  P  APPPP   PP    P P E PP  PP
Sbjct: 520 GVPTGSP-SPDLAPAAEPAPGAAPPPP---PPLPGLPSPQEAPPSAPP 563



 Score = 32.0 bits (71), Expect = 2.9
 Identities = 23/75 (30%), Positives = 27/75 (36%), Gaps = 7/75 (9%)

Query: 772 ASDPVP--LPPARPPTRDNPKHGSSLNRTPSDYDLLI-----PPLGEDAFDALPPSLPPP 824
           A++P P   PP  PP    P    +    P     L      PP      D  PP  PPP
Sbjct: 533 AAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPP 592

Query: 825 PPPARHSLIEHSKPP 839
           PPP     +    PP
Sbjct: 593 PPPGTDGPVPPPPPP 607



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 41/159 (25%), Positives = 54/159 (33%), Gaps = 30/159 (18%)

Query: 775 PVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPL------GEDAFDALPPSLPPPPPPA 828
           P   PP  PP   +P+   +    P   DL  PP       G D    +PP  PPPPPP 
Sbjct: 558 PPSAPPQAPPLPGSPEPPPA---PPLPGDLPPPPPPPPPPPGTDG--PVPPPPPPPPPPP 612

Query: 829 RHSLIEHSKPPGSSSRPSSG-----------QDLFLLPSDPFVDLASGQVPLPPARRLPG 877
                    PP +  R  S            Q  F +P   +V L   Q+       L  
Sbjct: 613 -------GGPPDALGRRDSELGPGVKAKKPIQTKFRMPLLNWVALKPSQITGTVFTELND 665

Query: 878 ENVKTNRTSQDY-DQLPSCSDGSQAPARPPKPRPRRTAP 915
           E V       D+ +Q  + S G        K +  + AP
Sbjct: 666 EKVLQELDMSDFEEQFKTKSQGPSLDLSALKSKAAQKAP 704


>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
          Length = 1170

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 67/276 (24%), Positives = 96/276 (34%), Gaps = 52/276 (18%)

Query: 482 GSSPLAQRRKP------QPDPLQIPHLSLPP-------VPPRLDLIQKGIVRSPCGSPTG 528
           G  P+  R +P       P P+ I H S P        +PPR   +         G P  
Sbjct: 517 GQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGP------GQPFL 570

Query: 529 SPKSSPCMVRKQDKPLPAP-----------PPPLRDPP------PPPPERPPP-----IP 566
              + P +      PLP P           PPP   PP      PPP  +PPP      P
Sbjct: 571 PTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHP 630

Query: 567 PDNRLSRHIHHVESVPSRDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGI---TASS 623
           P ++   H HH+   P    PM    + P       Q    R+  +   + G+   T S 
Sbjct: 631 PQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRM--QCPQRQGLRHNTTSQ 688

Query: 624 NVNGRHSRVGSDPVLMRKHRRHDLPLEGAKVF---SNGHLGSEEYDVPPRLSPPPPVTTL 680
           NV+ R  +    P   R     +LP+  + V    S+    +    V P +S  PP   +
Sbjct: 689 NVSKRPMQ-QMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAV 747

Query: 681 LPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHP 716
             S    G     +  K   PV +  +E K  +  P
Sbjct: 748 AGSRSSQG--KTEVKVKPASPVAQPKEEAKTETEFP 781



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 88/402 (21%), Positives = 134/402 (33%), Gaps = 106/402 (26%)

Query: 534 PCMVRKQDKPLPAPPPPLRDPPPPPPERP-----PPIPPDNRLS-RHIHHVESVPSRDPP 587
           P ++  Q   +P  PPP   PPPPP ++P      P P    L  +H HH    P +   
Sbjct: 306 PALLPTQPPVVPQAPPP---PPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPS--PPQGMH 360

Query: 588 MPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHRRHDL 647
           MP +   PR            ++      P    + ++N         PV         +
Sbjct: 361 MPPQLETPR-----------MMMTPPPVTPQQPKNIHINPHFKGTVVTPV--------QV 401

Query: 648 PLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDDD 707
           PL          +G + +  PP      P           GP+ NS S+  R P++   D
Sbjct: 402 PLLPVPSQPRPAVGPQRFPGPPEFPQHTP-----------GPVPNSFSQPPRLPLQ---D 447

Query: 708 EYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGD 767
           +++ P                  PP +  D          G S E +             
Sbjct: 448 QWRAP------------------PPPQDRDPFFL------GVSGEPR---------FPSH 474

Query: 768 VFDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDA----FDALPPSLPP 823
           +F     P P PP  PPT  N  H     ++P  +    P   +      F    P  P 
Sbjct: 475 LFLEQRSPPPPPP--PPTLLNSSHPVP-TQSPLPFTQPGPAFNQQGQQPVFPRERPVRPA 531

Query: 824 PPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARRLPGENVKTN 883
             PP    ++  S+P  +++RP      F+ P  PF+    GQ  LP        + + N
Sbjct: 532 LQPPGPVGILHFSQPGSATTRP------FIPPRQPFLP-GPGQPFLPT-------HTQPN 577

Query: 884 RTSQDYDQLPSCSDGSQAPARPPKPRPRRTAPEIHHRKPHGP 925
                +  LP        P   P+P+  +  P   H+ PH P
Sbjct: 578 LQGPLHPPLP--------PPHQPQPQQPQQQPPPQHQPPHQP 611



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 12/90 (13%)

Query: 477 PVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCM 536
           P  +PG  P +  + P+  PLQ      PP P   D    G+        +G P+    +
Sbjct: 426 PQHTPGPVPNSFSQPPRL-PLQ-DQWRAPPPPQDRDPFFLGV--------SGEPRFPSHL 475

Query: 537 VRKQDKPLPAPPPP--LRDPPPPPPERPPP 564
             +Q  P P PPPP  L    P P + P P
Sbjct: 476 FLEQRSPPPPPPPPTLLNSSHPVPTQSPLP 505


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 95/402 (23%), Positives = 131/402 (32%), Gaps = 76/402 (18%)

Query: 544 LPAPPPPLRDPPPPPP------ERPP--------------PIPPDNRLSRHIHHVESVPS 583
           +P PPPP   PPPPP       E+P                I    +L + + +  S P 
Sbjct: 1   MPVPPPPA--PPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPI 58

Query: 584 RDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHR 643
            D P    A      FG          G G    G        G  S  G  P  +    
Sbjct: 59  LDKPKGAGAGGGGGGFG----------GGG----GFGGGGGGGGGGSFGGGGPPGLGGLF 104

Query: 644 RHDLP-LEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPV 702
           +  +P L       N   GS     PP L P    T+  P    +GP    +        
Sbjct: 105 QAGMPKLRSTANRDNDSGGSR----PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSG 160

Query: 703 EEDDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSI 762
             +    ++P   P  + S+P    ++ PPV S      + +  H   S      P    
Sbjct: 161 PPEPQRNRMPPPRP-DVGSKPD---SIPPPVPSTPRP--IQSSPHNRGSPPVPGGP---- 210

Query: 763 YLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLI---PPLGEDAFDALPP 819
                       P P PP  P  R     G S+ ++P          PPL      AL  
Sbjct: 211 --------RQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDD 262

Query: 820 SLPPPPPPARHSLIEHSK----PPGSSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARRL 875
             PPPPPP  +    H +    PP  +++P        +PS P    +S   P PP    
Sbjct: 263 KPPPPPPPVGNRPSIHREAVPPPPPQNNKPP-------VPSTPRPSASSQAPPPPPPPSR 315

Query: 876 PGENVKTNRTSQDYDQLPSCSDG--SQAPARPPKPRPRRTAP 915
           PG       +S   D+ P       S + + PP P P R+ P
Sbjct: 316 PGP-PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP 356



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 108/436 (24%), Positives = 136/436 (31%), Gaps = 127/436 (29%)

Query: 503 SLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAP---PPPLRDPPPPPP 559
           S PP+ P           SP   P   P  SP    +   P P     PPP  D    P 
Sbjct: 124 SRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPG--HRSGPPEPQRNRMPPPRPDVGSKPD 181

Query: 560 ERPPPIPPDNRLSRHIHHVESVPSRDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGI 619
             PPP+P   R  +   H        PP+P                     G   P PG 
Sbjct: 182 SIPPPVPSTPRPIQSSPHNRG----SPPVP--------------------GGPRQPSPGP 217

Query: 620 TASSNVNGRHSRVGSDPVLMRKHRRHDLPLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTT 679
           T       R + +G   +          PL  +  FSN           P L P P    
Sbjct: 218 TPPPFPGNRGTALGGGSI-------RQSPLSSSSPFSN----------RPPLPPTP---- 256

Query: 680 LLPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNG 739
                      + +L +K   P     +    PS H  ++   P    N KPPV S    
Sbjct: 257 -----------SRALDDKPPPPPPPVGNR---PSIHREAVPPPPP--QNNKPPVPS---- 296

Query: 740 HCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTP 799
                 T  PS+                   S + P P PP+RP     P   S  + TP
Sbjct: 297 ------TPRPSA------------------SSQAPPPPPPPSRPGPPPLPPSSSGNDETP 332

Query: 800 SDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPF 859
                 +P        +L  S PP P P R   +    PP  S R          P  P 
Sbjct: 333 R-----LPQRNL----SLSSSTPPLPSPGRSGPL----PPPPSER----------PPPPV 369

Query: 860 VDLASGQVPLPPARRLPGENVKTNRTSQDYDQLPSCS--DGSQAPARPPKP--RPRRTAP 915
            D      PLPP   +   N  T+R      QLPS S  D  ++  RPP P  RP   AP
Sbjct: 370 RDPPGRSGPLPPPPPV-SRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAP 428

Query: 916 EIHHRKPHGPEAALEN 931
                 P  P  ++ N
Sbjct: 429 -----PPPPPSTSIRN 439



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 42/135 (31%), Positives = 54/135 (40%), Gaps = 30/135 (22%)

Query: 477 PVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLD-------LIQKGIVRSPCGSPTGS 529
           PV S      + +  P P P   P    PP+PP          L Q+ +  S    P  S
Sbjct: 293 PVPSTPRPSASSQAPPPPPPPSRP--GPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS 350

Query: 530 P-KSSPCMVRKQDKPLPAPPPPLRDPP----PPPPERPPPIPPDNRLSRHIHHVESVPSR 584
           P +S P        P   PPPP+RDPP    P PP  PPP+  +   SR +     +PSR
Sbjct: 351 PGRSGPL----PPPPSERPPPPVRDPPGRSGPLPP--PPPVSRNGSTSRALPATPQLPSR 404

Query: 585 D----------PPMP 589
                      PP+P
Sbjct: 405 SGVDSPRSGPRPPLP 419



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 106/419 (25%), Positives = 129/419 (30%), Gaps = 128/419 (30%)

Query: 474 QNSPVTSPGSSPL-AQRRKPQPDPLQIPHLSLPPVPPRLDLIQKG--IVRSPCGSPT--- 527
           Q+SP  + GS P+    R+P P P        PP P        G  I +SP  S +   
Sbjct: 195 QSSP-HNRGSPPVPGGPRQPSPGPTP------PPFPGNRGTALGGGSIRQSPLSSSSPFS 247

Query: 528 GSPKSSPCMVRKQDKPLPAPPPPLRD---------PPPPPPERPPPIP--PDNRLSRHIH 576
             P   P   R  D   P PPPP+ +         PPPPP    PP+P  P    S    
Sbjct: 248 NRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAP 307

Query: 577 HVESVPSRDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDP 636
                PSR  P PL    P    G ++    RL     P+  ++ SS          S P
Sbjct: 308 PPPPPPSRPGPPPL----PPSSSGNDETP--RL-----PQRNLSLSS----------STP 346

Query: 637 VLMRKHRRHDLPLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSE 696
            L    R   LP                   PP   PPPPV                   
Sbjct: 347 PLPSPGRSGPLP------------------PPPSERPPPPV------------------- 369

Query: 697 KTRDPVEEDDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSN 756
             RDP         +P   PVS N   S      P + S        +G   P S  +  
Sbjct: 370 --RDPPGRSG---PLPPPPPVSRNGSTSRALPATPQLPS-------RSGVDSPRSGPRP- 416

Query: 757 IPDLSIYLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDA 816
                               PLPP RP     P    S +      D       E  F  
Sbjct: 417 --------------------PLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYF 456

Query: 817 LPPS-LPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARR 874
            P S LPPP P  + +    SK   + SR  S +               G  PLPP  R
Sbjct: 457 HPISDLPPPEPYVQTTKSYPSKLARNESRSGSNR------------RERGAPPLPPIPR 503


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 95/402 (23%), Positives = 131/402 (32%), Gaps = 76/402 (18%)

Query: 544 LPAPPPPLRDPPPPPP------ERPP--------------PIPPDNRLSRHIHHVESVPS 583
           +P PPPP   PPPPP       E+P                I    +L + + +  S P 
Sbjct: 1   MPVPPPPA--PPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPI 58

Query: 584 RDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHR 643
            D P    A      FG          G G    G        G  S  G  P  +    
Sbjct: 59  LDKPKGAGAGGGGGGFG----------GGG----GFGGGGGGGGGGSFGGGGPPGLGGLF 104

Query: 644 RHDLP-LEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPV 702
           +  +P L       N   GS     PP L P    T+  P    +GP    +        
Sbjct: 105 QAGMPKLRSTANRDNDSGGSR----PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSG 160

Query: 703 EEDDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSI 762
             +    ++P   P  + S+P    ++ PPV S      + +  H   S      P    
Sbjct: 161 PPEPQRNRMPPPRP-DVGSKPD---SIPPPVPSTPRP--IQSSPHNRGSPPVPGGP---- 210

Query: 763 YLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLI---PPLGEDAFDALPP 819
                       P P PP  P  R     G S+ ++P          PPL      AL  
Sbjct: 211 --------RQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDD 262

Query: 820 SLPPPPPPARHSLIEHSK----PPGSSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARRL 875
             PPPPPP  +    H +    PP  +++P        +PS P    +S   P PP    
Sbjct: 263 KPPPPPPPVGNRPSIHREAVPPPPPQNNKPP-------VPSTPRPSASSQAPPPPPPPSR 315

Query: 876 PGENVKTNRTSQDYDQLPSCSDG--SQAPARPPKPRPRRTAP 915
           PG       +S   D+ P       S + + PP P P R+ P
Sbjct: 316 PGP-PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP 356



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 108/436 (24%), Positives = 136/436 (31%), Gaps = 127/436 (29%)

Query: 503 SLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAP---PPPLRDPPPPPP 559
           S PP+ P           SP   P   P  SP    +   P P     PPP  D    P 
Sbjct: 124 SRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPG--HRSGPPEPQRNRMPPPRPDVGSKPD 181

Query: 560 ERPPPIPPDNRLSRHIHHVESVPSRDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGI 619
             PPP+P   R  +   H        PP+P                     G   P PG 
Sbjct: 182 SIPPPVPSTPRPIQSSPHNRG----SPPVP--------------------GGPRQPSPGP 217

Query: 620 TASSNVNGRHSRVGSDPVLMRKHRRHDLPLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTT 679
           T       R + +G   +          PL  +  FSN           P L P P    
Sbjct: 218 TPPPFPGNRGTALGGGSI-------RQSPLSSSSPFSN----------RPPLPPTP---- 256

Query: 680 LLPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNG 739
                      + +L +K   P     +    PS H  ++   P    N KPPV S    
Sbjct: 257 -----------SRALDDKPPPPPPPVGNR---PSIHREAVPPPPP--QNNKPPVPS---- 296

Query: 740 HCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTP 799
                 T  PS+                   S + P P PP+RP     P   S  + TP
Sbjct: 297 ------TPRPSA------------------SSQAPPPPPPPSRPGPPPLPPSSSGNDETP 332

Query: 800 SDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPF 859
                 +P        +L  S PP P P R   +    PP  S R          P  P 
Sbjct: 333 R-----LPQRNL----SLSSSTPPLPSPGRSGPL----PPPPSER----------PPPPV 369

Query: 860 VDLASGQVPLPPARRLPGENVKTNRTSQDYDQLPSCS--DGSQAPARPPKP--RPRRTAP 915
            D      PLPP   +   N  T+R      QLPS S  D  ++  RPP P  RP   AP
Sbjct: 370 RDPPGRSGPLPPPPPV-SRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAP 428

Query: 916 EIHHRKPHGPEAALEN 931
                 P  P  ++ N
Sbjct: 429 -----PPPPPSTSIRN 439



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 42/135 (31%), Positives = 54/135 (40%), Gaps = 30/135 (22%)

Query: 477 PVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLD-------LIQKGIVRSPCGSPTGS 529
           PV S      + +  P P P   P    PP+PP          L Q+ +  S    P  S
Sbjct: 293 PVPSTPRPSASSQAPPPPPPPSRP--GPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS 350

Query: 530 P-KSSPCMVRKQDKPLPAPPPPLRDPP----PPPPERPPPIPPDNRLSRHIHHVESVPSR 584
           P +S P        P   PPPP+RDPP    P PP  PPP+  +   SR +     +PSR
Sbjct: 351 PGRSGPL----PPPPSERPPPPVRDPPGRSGPLPP--PPPVSRNGSTSRALPATPQLPSR 404

Query: 585 D----------PPMP 589
                      PP+P
Sbjct: 405 SGVDSPRSGPRPPLP 419



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 106/419 (25%), Positives = 129/419 (30%), Gaps = 128/419 (30%)

Query: 474 QNSPVTSPGSSPL-AQRRKPQPDPLQIPHLSLPPVPPRLDLIQKG--IVRSPCGSPT--- 527
           Q+SP  + GS P+    R+P P P        PP P        G  I +SP  S +   
Sbjct: 195 QSSP-HNRGSPPVPGGPRQPSPGPTP------PPFPGNRGTALGGGSIRQSPLSSSSPFS 247

Query: 528 GSPKSSPCMVRKQDKPLPAPPPPLRD---------PPPPPPERPPPIP--PDNRLSRHIH 576
             P   P   R  D   P PPPP+ +         PPPPP    PP+P  P    S    
Sbjct: 248 NRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAP 307

Query: 577 HVESVPSRDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDP 636
                PSR  P PL    P    G ++    RL     P+  ++ SS          S P
Sbjct: 308 PPPPPPSRPGPPPL----PPSSSGNDETP--RL-----PQRNLSLSS----------STP 346

Query: 637 VLMRKHRRHDLPLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSE 696
            L    R   LP                   PP   PPPPV                   
Sbjct: 347 PLPSPGRSGPLP------------------PPPSERPPPPV------------------- 369

Query: 697 KTRDPVEEDDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSN 756
             RDP         +P   PVS N   S      P + S        +G   P S  +  
Sbjct: 370 --RDPPGRSG---PLPPPPPVSRNGSTSRALPATPQLPS-------RSGVDSPRSGPRP- 416

Query: 757 IPDLSIYLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDA 816
                               PLPP RP     P    S +      D       E  F  
Sbjct: 417 --------------------PLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYF 456

Query: 817 LPPS-LPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARR 874
            P S LPPP P  + +    SK   + SR  S +               G  PLPP  R
Sbjct: 457 HPISDLPPPEPYVQTTKSYPSKLARNESRSGSNR------------RERGAPPLPPIPR 503


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 31/95 (32%), Positives = 43/95 (45%), Gaps = 7/95 (7%)

Query: 474 QNSPVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSS 533
           + +P   P  +P A    P P P   P +++PP PP   +        P  +P+G P   
Sbjct: 307 RGAPPPPPSRAPTAA---PPPPPPSRPSVAVPPPPPNR-MYPPPPPALPSSAPSGPPPPP 362

Query: 534 PCMVRKQDKPLPAPPPPLRDPPPPPPERPPPIPPD 568
           P ++        APPPP   PPPP P  PP +P D
Sbjct: 363 PSVLGVGPV---APPPPPPPPPPPGPPPPPGLPSD 394



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 39/121 (32%), Positives = 48/121 (39%), Gaps = 25/121 (20%)

Query: 480 SPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGI-----VRSPCGSPTGSPKSSP 534
           +P   P ++   P P P   PH S PP PP      +G       R+P  +P   P S P
Sbjct: 276 APPPPPPSRGGPPPPPPP--PHNSGPPPPPARG---RGAPPPPPSRAPTAAPPPPPPSRP 330

Query: 535 CMVRKQDKPLPAPPPPLRDPPPPP------PERPPPIPPDNRLSRHIHHVESVPSRDPPM 588
            +       +P PPP    PPPPP      P  PPP PP       +  V   P   PP 
Sbjct: 331 SVA------VPPPPPNRMYPPPPPALPSSAPSGPPPPPPS---VLGVGPVAPPPPPPPPP 381

Query: 589 P 589
           P
Sbjct: 382 P 382



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 34/100 (34%), Positives = 40/100 (40%), Gaps = 14/100 (14%)

Query: 775 PVPLPPAR--PPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPARHSL 832
           P P PP+R  PP    P H S     P+      PP    A    P + PPPPPP+R S+
Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRA----PTAAPPPPPPSRPSV 332

Query: 833 IEHSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQVPLPPA 872
                PP     P        LPS       SG  P PP+
Sbjct: 333 AVPPPPPNRMYPPPPP----ALPS----SAPSGPPPPPPS 364



 Score = 37.4 bits (85), Expect = 0.070
 Identities = 34/106 (32%), Positives = 39/106 (36%), Gaps = 20/106 (18%)

Query: 488 QRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAP 547
           +R+ P P P   P    PP PP            P    +G P   P   R    P P+ 
Sbjct: 273 RRQAPPPPP---PSRGGPPPPP------------PPPHNSGPPPP-PARGRGAPPPPPSR 316

Query: 548 PPPLRDPPPPP--PERPPPIPPDNRLSRHIHHV--ESVPSRDPPMP 589
            P    PPPPP  P    P PP NR+          S PS  PP P
Sbjct: 317 APTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPP 362



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 20/47 (42%), Positives = 24/47 (51%), Gaps = 6/47 (12%)

Query: 527 TGSPKSSPCMVRKQDKPLPAPPPPLRD---PPPPPPERPPPIPPDNR 570
           TG  ++    +R+Q    P PPPP R    PPPPPP    P PP  R
Sbjct: 262 TGGVEAVKNELRRQ---APPPPPPSRGGPPPPPPPPHNSGPPPPPAR 305


>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
          Length = 3571

 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 10/80 (12%)

Query: 492  PQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAPPPPL 551
            P+  P   P   LPP PP+   +    + +   +P  +P  +P          P PPPP 
Sbjct: 1955 PETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTP----------PPPPPPP 2004

Query: 552  RDPPPPPPERPPPIPPDNRL 571
              PPPPPP  PP  PP  +L
Sbjct: 2005 PPPPPPPPPPPPSAPPQVQL 2024



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 39/129 (30%), Positives = 51/129 (39%), Gaps = 24/129 (18%)

Query: 459  LMMNRLANVRKCTDRQNSPVTSPG----------SSPLAQRRKPQPDPLQIPHLSLPPVP 508
            +    L  ++K +D     V  PG          S P A    P   P+ +P ++ P   
Sbjct: 3014 MAQQELDRIKKASDVLGLTVQQPGMMDSSSLHGISLPTAYPGLPGLPPVLLPGMNGPSSL 3073

Query: 509  PRLDLIQKGIVRSPCGS-----PTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPPERPP 563
            P     Q     +P G+     PT S  SSP +         AP  PL   PPPPP  PP
Sbjct: 3074 PGFP--QNSNTLTPPGAGMLGFPT-SATSSPALSLSS-----APTKPLLQTPPPPPPPPP 3125

Query: 564  PIPPDNRLS 572
            P PP + LS
Sbjct: 3126 P-PPSSSLS 3133



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 19/59 (32%), Positives = 23/59 (38%)

Query: 531  KSSPCMVRKQDKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVESVPSRDPPMP 589
            K  P      + P P PPPP   P PP P    P+   N +S  +      P   PP P
Sbjct: 1946 KLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPP 2004



 Score = 37.0 bits (84), Expect = 0.091
 Identities = 34/111 (30%), Positives = 42/111 (37%), Gaps = 13/111 (11%)

Query: 771  SASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPARH 830
            S+ +  P PP  PP    P   SS+        + IP        A PP+ PPPPPP   
Sbjct: 1953 SSPETPPPPPPPPPLPPAPPQPSSMG------PVKIPNTVSTPLQAPPPTPPPPPPPPPP 2006

Query: 831  SLIEHSKPPGSSSRPSSGQ-----DLFLLPSDPFVDLASGQVPLPPARRLP 876
                   PP   S P   Q     DL L PS     +    +P   A +LP
Sbjct: 2007 P--PPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLP 2055



 Score = 35.0 bits (79), Expect = 0.35
 Identities = 15/27 (55%), Positives = 16/27 (59%), Gaps = 2/27 (7%)

Query: 541  DKPLPAPPPPLRDPPPPPPERPPPIPP 567
            DK  P  P     PPPPPP  PPP+PP
Sbjct: 1945 DKLYPISPSSPETPPPPPP--PPPLPP 1969



 Score = 32.0 bits (71), Expect = 2.9
 Identities = 34/134 (25%), Positives = 46/134 (34%), Gaps = 15/134 (11%)

Query: 448  DLDDDDDREESLMMNRLANVRKCT--------DRQNSPVTSPGS---SPLAQRRKPQPDP 496
            D  D+   E+S+        + CT            +P  S GS   +PL    KP+P+ 
Sbjct: 2297 DAQDESQTEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEK 2356

Query: 497  LQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRK-QDKPLPAPP--PPLRD 553
               P    P   P+          +    P  S  S P      Q +P P PP  P L  
Sbjct: 2357 TS-PKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIG 2415

Query: 554  PPPPPPERPPPIPP 567
             PP   + P P  P
Sbjct: 2416 RPPSASQTPVPSSP 2429


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 71/253 (28%), Positives = 93/253 (36%), Gaps = 46/253 (18%)

Query: 476 SPVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPC 535
           SP  SP  SPLA      P+ L +  L  P  PP    +Q     SP  SP  SP ++P 
Sbjct: 410 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF--SPPASPPVSPSATPP 467

Query: 536 MVRKQD---KPLPAPPPPLRDPP-----PPPPERPPPI----------PPDNRLSRHIHH 577
                     PL  PP P   PP      PPP+ PPP+          PP    +     
Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 527

Query: 578 VESVPSRDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPK-PGITASSNVNGRHSRVGSDP 636
           ++++PS  PP       P   F  +  +    L    P+ P + A+  +    S   S P
Sbjct: 528 LQALPS--PPASFPGQAP---FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS-P 581

Query: 637 VLMRKHRRHDLPLEGAKVFSNGHLGSEEYDVPPRLS-----PPPPVTTLLPSIKCTGP-L 690
            L    R    P  G     +G          PRL+      PPP  +  PS   +GP L
Sbjct: 582 TLQAPRRP---PTPGPDTSVSG----------PRLTLALAPGPPPPPSRSPSSTLSGPDL 628

Query: 691 ANSLSEKTRDPVE 703
           A   S  T  P E
Sbjct: 629 AGHSSSATSTPEE 641



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 92/364 (25%), Positives = 123/364 (33%), Gaps = 57/364 (15%)

Query: 475 NSPVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSP 534
           +S + SP  SPLA      P  L +P L  PP PP    +      SP  +P+    ++ 
Sbjct: 378 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL------SPLATPSPQAPNAL 431

Query: 535 CMVRKQDKPLPAPPPPLR---DPPPPPPERPPPIPPDN---RLSRHIHHVESVPSRDPPM 588
            +   Q    P P PP++    PP  PP  P   PP      L+     V   P   PPM
Sbjct: 432 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 491

Query: 589 PLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHRRHDLP 648
              A  P            +L       P   A+  +    S   S P            
Sbjct: 492 SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP------------ 539

Query: 649 LEGAKVFS-NGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDDD 707
             G   FS +  L       PP  +PP     LL  +  + P + +L    R P    D 
Sbjct: 540 --GQAPFSPSASLPMSPLATPPPQAPPVLAAPLL-QVPPSPPASPTLQAPRRPPTPGPDT 596

Query: 708 EYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTH--GPSSEKKSNIPDLSIYLK 765
               P          P       PP RS  +    L+G    G SS   S   +L  Y  
Sbjct: 597 SVSGPRLTLALAPGPP------PPPSRSPSS---TLSGPDLAGHSSSATSTPEELRGYDS 647

Query: 766 GDVFDSASDPVPLPPARPPTRDNPK-HGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPP 824
           G    +A+ P       PP  +    H ++ +R P+      PPL   AF    P  P P
Sbjct: 648 GPEGGAAASP-------PPDAELAACHPAAWSRGPA------PPL---AFRG-APGAPLP 690

Query: 825 PPPA 828
            PPA
Sbjct: 691 WPPA 694



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 115/496 (23%), Positives = 152/496 (30%), Gaps = 106/496 (21%)

Query: 476 SPVTSPGSS-------PLAQRRKPQPDPLQIPHLSLPPV-PPRLDLIQK--GIVRSPCGS 525
           +P++SP  S       P A     QP P  +  L  P V PPR D       +  SP  +
Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306

Query: 526 PTGS-------PKSSPCMVRKQD------KPLPAPPPPLRDPP-----PPPPERPPPIPP 567
           P+ S       P + P              PLP  PP    PP     P PP  PP    
Sbjct: 307 PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAT 366

Query: 568 DNRLSRHIHHVESVPSRDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNG 627
            +  S  +    S     P  PL    P+                    P   A   +  
Sbjct: 367 TSLGSPTLQATHSFLPSPPLSPLATPPPQ-------------------APPALALPPLQA 407

Query: 628 RHSRVGSDPVLMRKHRRHDLPLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLP-SIKC 686
             S   S P+          PL      +   L       P   SPPP      P S   
Sbjct: 408 PPSPPASPPLS---------PLATPSPQAPNALAVHLLQAP--FSPPPSPPVQAPFSPPA 456

Query: 687 TGPLANSLSEKTRDPVEEDDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGT 746
           + P++ S +  ++ P        ++P S P S    PS      PP              
Sbjct: 457 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS----ATPP-------------- 498

Query: 747 HGPSSEKKSNIPDLSIYLKGDVFDSASDPVPL-----PPARPPTRDNPKHGSSLNRTPSD 801
             P +      P L +         A    PL     PPA  P +      +SL  +P  
Sbjct: 499 --PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP-- 554

Query: 802 YDLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVD 861
             L  PP       A P    PP PPA  +L    +P      P+ G D  +  S P + 
Sbjct: 555 --LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP------PTPGPDTSV--SGPRLT 604

Query: 862 LASGQVPLPPARRLP----------GENVKTNRTSQDYDQLPSCSDGSQAPARPPKPRPR 911
           LA    P PP  R P          G +     T ++     S  +G  A + PP     
Sbjct: 605 LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA 664

Query: 912 RTAPEIHHRKPHGPEA 927
              P    R P  P A
Sbjct: 665 ACHPAAWSRGPAPPLA 680


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 30/75 (40%), Positives = 38/75 (50%), Gaps = 5/75 (6%)

Query: 495 DPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAPPPPLRDP 554
           D + I    LPP+PP           +P G PT SP   P   +++ + LPA P PL  P
Sbjct: 786 DSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASP---PVPAKEEPEELPAAPGPLPPP 842

Query: 555 PPPPPERPPPI--PP 567
           PPPPP  P P+  PP
Sbjct: 843 PPPPPPVPGPVTLPP 857



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 65/251 (25%), Positives = 87/251 (34%), Gaps = 30/251 (11%)

Query: 455 REESLMMNRLANVRKCTDRQNSPVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLI 514
           RE+SL ++   +    T    + +T P   PL       P P  +P    PP  P     
Sbjct: 610 REDSLEVSSFCSEALVTC---AALTHPRVPPLQPMGPTCPTPAPVP----PPEAP----- 657

Query: 515 QKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRH 574
                R+P   P G   S   M      P   P P      P P  RP P    N L   
Sbjct: 658 --SPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMP---SAGPVPSARPGPPTTANHLGLS 712

Query: 575 IHHVESVPSRDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGS 634
           +  + SVP R  P P          G+N+     L   G+P P I       GR  R   
Sbjct: 713 VPGLVSVPPRLLPGP-----ENHRAGSNE--DPILAPSGTPPPTIPPDETFGGRVPR--- 762

Query: 635 DPVLMRKHRRHDLPLE-GAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANS 693
            P  +   +     +E   +  S+  +      +PP L PPPP     P I  TGP   S
Sbjct: 763 -PAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPP-LPPPPPSGATPPPIAPTGPPTAS 820

Query: 694 LSEKTRDPVEE 704
                ++  EE
Sbjct: 821 PPVPAKEEPEE 831



 Score = 39.3 bits (90), Expect = 0.018
 Identities = 26/76 (34%), Positives = 31/76 (40%), Gaps = 3/76 (3%)

Query: 543 PLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVESVPSRDPPMPLEAWCPRDVFGTN 602
           PLP PPP    PPP  P  PP   P          + + P   PP P     P  V G  
Sbjct: 797 PLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPP---PPPVPGPV 853

Query: 603 QLVGCRLLGEGSPKPG 618
            L   +L+ EG+P  G
Sbjct: 854 TLPPPQLVPEGTPGGG 869



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 72/304 (23%), Positives = 91/304 (29%), Gaps = 97/304 (31%)

Query: 530 PKSSPCMVRKQDKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVESVPSRDP--- 586
           P+  P        P PAP PP   P  P P R PP  P   +      V S+PS  P   
Sbjct: 633 PRVPPLQPMGPTCPTPAPVPP---PEAPSPFRAPPFHPPGPMPS----VGSMPSAGPMPS 685

Query: 587 --PMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHRR 644
             PMP     P                  S +PG   ++N  G      S P L+    R
Sbjct: 686 AGPMPSAGPVP------------------SARPGPPTTANHLGL-----SVPGLVSVPPR 722

Query: 645 HDLPLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEE 704
               L G +   N   GS E  +      PPP    +P  +  G      +    D  E 
Sbjct: 723 L---LPGPE---NHRAGSNEDPILAPSGTPPPT---IPPDETFGGRVPRPAFVHYDKEEA 773

Query: 705 DDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYL 764
            D E  + S    S+   P     + PP                                
Sbjct: 774 SDVEISLESDSDDSVVIVPEGLPPLPPPP------------------------------- 802

Query: 765 KGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGE-DAFDALPPSLPP 823
                 S + P P+ P  PPT   P                +P   E +   A P  LPP
Sbjct: 803 -----PSGATPPPIAPTGPPTASPP----------------VPAKEEPEELPAAPGPLPP 841

Query: 824 PPPP 827
           PPPP
Sbjct: 842 PPPP 845



 Score = 35.4 bits (80), Expect = 0.26
 Identities = 13/23 (56%), Positives = 15/23 (65%)

Query: 546 APPPPLRDPPPPPPERPPPIPPD 568
           APPPP   P  PPPE PP + P+
Sbjct: 976 APPPPTLPPALPPPESPPKVQPE 998



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 32/105 (30%), Positives = 41/105 (39%), Gaps = 10/105 (9%)

Query: 807 PPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVD----- 861
           PP     F A PP  PP P P+  S+      P +   PS+G      P  P        
Sbjct: 653 PPEAPSPFRA-PPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGL 711

Query: 862 LASGQVPLPPARRLPGENVKTNRTSQDYDQLPSCSDGSQAPARPP 906
              G V +PP R LPG       +++D    PS   G+  P  PP
Sbjct: 712 SVPGLVSVPP-RLLPGPENHRAGSNEDPILAPS---GTPPPTIPP 752



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 21/116 (18%)

Query: 771 SASDPVPLPPARPPTRDNPKH--GSSLNRTP---------SDYDLLIPPLGEDAF----D 815
           S  DP+  P   PP    P    G  + R           SD ++ +    +D+     +
Sbjct: 734 SNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPE 793

Query: 816 ALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQVPLPP 871
            LPP  PPPP  A    I  + PP +S    + ++   LP+ P      G +P PP
Sbjct: 794 GLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAP------GPLPPPP 843


>gi|4557329 fas ligand [Homo sapiens]
          Length = 281

 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 23/54 (42%), Positives = 29/54 (53%)

Query: 521 SPCGSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRH 574
           +P G+    P S P    ++  P P PPPPL  PPPPPP  P P+PP  +   H
Sbjct: 24  APPGTVLPCPTSVPRRPGQRRPPPPPPPPPLPPPPPPPPLPPLPLPPLKKRGNH 77



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 23/66 (34%), Positives = 26/66 (39%), Gaps = 14/66 (21%)

Query: 525 SPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVESVPSR 584
           S   SP + P  V      +P  P   R PPPPPP   PP PP              P  
Sbjct: 17  SSASSPWAPPGTVLPCPTSVPRRPGQRRPPPPPPPPPLPPPPP--------------PPP 62

Query: 585 DPPMPL 590
            PP+PL
Sbjct: 63  LPPLPL 68


>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
          Length = 1312

 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 38/133 (28%), Positives = 53/133 (39%), Gaps = 20/133 (15%)

Query: 486 LAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSP--------------CGSPTGSPK 531
           +A+ R    DP+ +P   +P + PRL   + G   SP               G+  G P 
Sbjct: 129 VAEVRIGDRDPIPLP---VPSLLPRLRAWRTGKTVSPQSNSSRPTCARHLTLGTGDGGPA 185

Query: 532 SSPCMVRKQDKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRH--IHHVESVPSRDPPMP 589
             P        P P+P      PPPPPP   PP PP  R   +   H  +   S  PP P
Sbjct: 186 PPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYS-PPPAP 244

Query: 590 LEAWCPRDVFGTN 602
            + + P +  G+N
Sbjct: 245 EQKYDPFEPTGSN 257



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 29/121 (23%), Positives = 43/121 (35%), Gaps = 26/121 (21%)

Query: 819 PSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPF--VDLASGQVPLPPARRLP 876
           PS PPPPP           PP   + P+   D++    DPF   D A    P P  +  P
Sbjct: 206 PSPPPPPP-----------PPAPPAPPAPRFDIY----DPFHPTDEAYSPPPAPEQKYDP 250

Query: 877 GENVKTNRTSQDYDQLPSCSDGSQAPARPPKPRPRRTAPEIHHRKPHGPEAALENVDAKI 936
            E   +N         PS S G+ +P    +        E    +  G   ++  +   +
Sbjct: 251 FEPTGSN---------PSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISETL 301

Query: 937 A 937
           A
Sbjct: 302 A 302


>gi|4758666 LATS homolog 1 [Homo sapiens]
          Length = 1130

 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 89/387 (22%), Positives = 139/387 (35%), Gaps = 106/387 (27%)

Query: 545 PAPPPPLRDPPPPPPER------------PPPIPPDNRLSRHIHHVESVPSRDPPMPLEA 592
           P PPP +R   PPPP R            PP   P+++  R+  ++E V SR  P+P  A
Sbjct: 236 PPPPPQVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGA 295

Query: 593 WCPRDVFGTNQLVGCRLLGEGSPKPGI-TASSNVNGRHSR------VGSDPVLMRKHRRH 645
           W                  EG P P + T+  N   +  R      VG  P++M+   + 
Sbjct: 296 W-----------------QEGYPPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKF 338

Query: 646 DLPLEGAKVFSNGHLGSEEYDVPPRL--------SPPPPVT----------------TLL 681
           + P  G     NG  G  ++ +   +         PPPP                  +  
Sbjct: 339 NFP-SGRPGMQNG-TGQTDFMIHQNVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAA 396

Query: 682 PSIKCTGPLANSLSEKTRDPVEEDDDEYKI---------PSSHPVSLNSQPSHCHNVKP- 731
           PS    G +  S+    R+    + + Y I         P S      S PS  H +   
Sbjct: 397 PSSYTNGSIPQSMMVPNRN--SHNMELYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTW 454

Query: 732 ----PVRSCDNGHCMLN-GTHGPSSEKKSNI-----------PDLSIYLKGDVFDSA--- 772
               PVRS    + + N  +H  +S+  +             P  S+ +      +A   
Sbjct: 455 QPNIPVRSNSFNNPLGNRASHSANSQPSATTVTAITPAPIQQPVKSMRVLKPELQTALAP 514

Query: 773 SDPVPLPPARPPTRDNP-KHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPARHS 831
           + P  +P      + +P   G++ N T      ++PP+ E      P    PPPP  +H 
Sbjct: 515 THPSWIPQPIQTVQPSPFPEGTASNVT------VMPPVAE-----APNYQGPPPPYPKHL 563

Query: 832 LIEH-SKPPGSSSRPSSGQDLFLLPSD 857
           L ++ S PP  S    S +D   LP +
Sbjct: 564 LHQNPSVPPYESISKPSKEDQPSLPKE 590


>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
          Length = 547

 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 29/78 (37%), Positives = 36/78 (46%), Gaps = 6/78 (7%)

Query: 521 SPCGSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVES 580
           SP  SP  SP SSP + +K       P  P+  PPPPPP  PPP P   RL         
Sbjct: 388 SPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLP------PP 441

Query: 581 VPSRDPPMPLEAWCPRDV 598
            P   PP+P +    R++
Sbjct: 442 PPPPPPPLPEKKLITRNI 459



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 28/103 (27%), Positives = 38/103 (36%), Gaps = 32/103 (31%)

Query: 476 SPVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPC 535
           SP  SP SSP   ++        +  ++ PP PP                          
Sbjct: 392 SPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPP-------------------------- 425

Query: 536 MVRKQDKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHV 578
                  P P PPP  +  PPPPP  PPP+P    ++R+I  V
Sbjct: 426 ------PPPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNIAEV 462



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 21/67 (31%), Positives = 24/67 (35%)

Query: 524 GSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVESVPS 583
           G+P+ SP  SP         LP     +R  P  P   PPP PP              P 
Sbjct: 383 GTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPP 442

Query: 584 RDPPMPL 590
             PP PL
Sbjct: 443 PPPPPPL 449


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.137    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,344,382
Number of Sequences: 37866
Number of extensions: 3421946
Number of successful extensions: 49080
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 459
Number of HSP's successfully gapped in prelim test: 1039
Number of HSP's that attempted gapping in prelim test: 22586
Number of HSP's gapped (non-prelim): 14394
length of query: 982
length of database: 18,247,518
effective HSP length: 112
effective length of query: 870
effective length of database: 14,006,526
effective search space: 12185677620
effective search space used: 12185677620
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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