Search of human proteins with 5360210

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5360210 poliovirus receptor related 2 isoform alpha
precursor [Homo sapiens]
         (479 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5360210 poliovirus receptor related 2 isoform alpha precursor...   969   0.0  
gi|112789532 poliovirus receptor related 2 isoform delta precurs...   719   0.0  
gi|209413732 poliovirus receptor isoform delta [Homo sapiens]         336   3e-92
gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]         336   3e-92
gi|209413730 poliovirus receptor isoform gamma [Homo sapiens]         335   4e-92
gi|209413728 poliovirus receptor isoform beta [Homo sapiens]          333   2e-91
gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]    213   4e-55
gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]    200   2e-51
gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]    182   4e-46
gi|11386199 poliovirus receptor-related 3 [Homo sapiens]              157   2e-38
gi|222136611 poliovirus receptor-related 4 [Homo sapiens]             116   5e-26
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho...    87   3e-17
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho...    86   6e-17
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]       82   1e-15
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]         77   5e-14
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]          77   5e-14
gi|21686977 cell adhesion molecule 4 [Homo sapiens]                    69   1e-11
gi|145275174 kin of IRRE-like 2 isoform c [Homo sapiens]               66   8e-11
gi|145275170 kin of IRRE-like 2 isoform a [Homo sapiens]               66   8e-11
gi|145275172 kin of IRRE-like 2 isoform b [Homo sapiens]               61   2e-09
gi|94538343 sialic acid binding Ig-like lectin 8 [Homo sapiens]        56   8e-08
gi|90903245 CD200 antigen isoform b [Homo sapiens]                     55   2e-07
gi|90903247 CD200 antigen isoform a precursor [Homo sapiens]           55   2e-07
gi|118572606 hemicentin 1 [Homo sapiens]                               54   3e-07
gi|157739930 TAP binding protein-like [Homo sapiens]                   53   5e-07
gi|98986445 carcinoembryonic antigen-related cell adhesion molec...    53   7e-07
gi|7657570 sialic acid binding Ig-like lectin 7 isoform 1 [Homo ...    51   2e-06
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                    51   3e-06
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    51   3e-06
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]                    51   3e-06

>gi|5360210 poliovirus receptor related 2 isoform alpha precursor
           [Homo sapiens]
          Length = 479

 Score =  969 bits (2506), Expect = 0.0
 Identities = 479/479 (100%), Positives = 479/479 (100%)

Query: 1   MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV 60
           MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV
Sbjct: 1   MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV 60

Query: 61  PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL 120
           PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL
Sbjct: 61  PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL 120

Query: 121 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV 180
           QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV
Sbjct: 121 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV 180

Query: 181 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV 240
           ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV
Sbjct: 181 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV 240

Query: 241 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS 300
           EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS
Sbjct: 241 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS 300

Query: 301 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDVGPL 360
           GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDVGPL
Sbjct: 301 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDVGPL 360

Query: 361 VWGAVGGTLLVLLLLAGGSLAFILLRVRRRRKSPGGAGGGASGDGGFYDPKAQVLGNGDP 420
           VWGAVGGTLLVLLLLAGGSLAFILLRVRRRRKSPGGAGGGASGDGGFYDPKAQVLGNGDP
Sbjct: 361 VWGAVGGTLLVLLLLAGGSLAFILLRVRRRRKSPGGAGGGASGDGGFYDPKAQVLGNGDP 420

Query: 421 VFWTPVVPGPMEPDGKDEEEEEEEEKAEKGLMLPPPPALEDDMESQLDGSLISRRAVYV 479
           VFWTPVVPGPMEPDGKDEEEEEEEEKAEKGLMLPPPPALEDDMESQLDGSLISRRAVYV
Sbjct: 421 VFWTPVVPGPMEPDGKDEEEEEEEEKAEKGLMLPPPPALEDDMESQLDGSLISRRAVYV 479


>gi|112789532 poliovirus receptor related 2 isoform delta precursor
           [Homo sapiens]
          Length = 538

 Score =  719 bits (1857), Expect = 0.0
 Identities = 358/397 (90%), Positives = 370/397 (93%), Gaps = 3/397 (0%)

Query: 1   MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV 60
           MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV
Sbjct: 1   MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV 60

Query: 61  PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL 120
           PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL
Sbjct: 61  PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL 120

Query: 121 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV 180
           QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV
Sbjct: 121 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV 180

Query: 181 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV 240
           ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV
Sbjct: 181 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV 240

Query: 241 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS 300
           EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS
Sbjct: 241 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS 300

Query: 301 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDVGPL 360
           GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP  +       
Sbjct: 301 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGA--- 357

Query: 361 VWGAVGGTLLVLLLLAGGSLAFILLRVRRRRKSPGGA 397
             G +GG +  ++  A  +   ++ R +R+ ++  GA
Sbjct: 358 TGGIIGGIIAAIIATAVAATGILICRQQRKEQTLQGA 394



 Score = 29.3 bits (64), Expect = 8.3
 Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 8/67 (11%)

Query: 418 GDPVFWTPVVPGP-----MEPDGKDEEEEEEEEKAEKGLMLPPPPALEDDMESQLDGSLI 472
           G P+   PV PGP     +  D +DEE EEEEE  +K   +    +     +S      +
Sbjct: 475 GSPI---PVPPGPPAVEDVSLDLEDEEGEEEEEYLDKINPIYDALSYSSPSDSYQGKGFV 531

Query: 473 SRRAVYV 479
             RA+YV
Sbjct: 532 MSRAMYV 538


>gi|209413732 poliovirus receptor isoform delta [Homo sapiens]
          Length = 392

 Score =  336 bits (861), Expect = 3e-92
 Identities = 186/372 (50%), Positives = 242/372 (65%), Gaps = 23/372 (6%)

Query: 19  WPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCHL-LPPVPGLYISLVTWQR 72
           WPLLL+ LL       G  DV VQ   +V G LG +V LPC+L +P +   ++S +TW R
Sbjct: 9   WPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWAR 68

Query: 73  PDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTV 132
                +   +A FH   GPS+      S+RL FV+A+        AEL++A+L + GL V
Sbjct: 69  HGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG------AELRNASLRMFGLRV 115

Query: 133 EDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPA 192
           EDEGNYTC F TFP+GS     WLRV+AKP+N AE QKV  + +P  +A C+S  GRPPA
Sbjct: 116 EDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPA 175

Query: 193 RISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIP 252
           +I+W S L      +QV G L+GTVTVTS + LVPS + DG  VTCKVEHESFE+P L+ 
Sbjct: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235

Query: 253 VTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGS 312
           V L+V YPPEVSISGYD+NWYLG+ +ATL+CD RSNPEPTGY+WSTT G  P  AVAQG+
Sbjct: 236 VNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGA 295

Query: 313 QLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDV--GPLVWGAVGGTLL 370
           QL+I  VD   NTT +C VTNA+G  +AE  + V+E P +    +    +++  +G  +L
Sbjct: 296 QLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLVLG--IL 353

Query: 371 VLLLLAGGSLAF 382
           V L+L G  + F
Sbjct: 354 VFLILLGIGIYF 365


>gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]
          Length = 417

 Score =  336 bits (861), Expect = 3e-92
 Identities = 186/372 (50%), Positives = 242/372 (65%), Gaps = 23/372 (6%)

Query: 19  WPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCHL-LPPVPGLYISLVTWQR 72
           WPLLL+ LL       G  DV VQ   +V G LG +V LPC+L +P +   ++S +TW R
Sbjct: 9   WPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWAR 68

Query: 73  PDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTV 132
                +   +A FH   GPS+      S+RL FV+A+        AEL++A+L + GL V
Sbjct: 69  HGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG------AELRNASLRMFGLRV 115

Query: 133 EDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPA 192
           EDEGNYTC F TFP+GS     WLRV+AKP+N AE QKV  + +P  +A C+S  GRPPA
Sbjct: 116 EDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPA 175

Query: 193 RISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIP 252
           +I+W S L      +QV G L+GTVTVTS + LVPS + DG  VTCKVEHESFE+P L+ 
Sbjct: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235

Query: 253 VTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGS 312
           V L+V YPPEVSISGYD+NWYLG+ +ATL+CD RSNPEPTGY+WSTT G  P  AVAQG+
Sbjct: 236 VNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGA 295

Query: 313 QLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDV--GPLVWGAVGGTLL 370
           QL+I  VD   NTT +C VTNA+G  +AE  + V+E P +    +    +++  +G  +L
Sbjct: 296 QLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLVLG--IL 353

Query: 371 VLLLLAGGSLAF 382
           V L+L G  + F
Sbjct: 354 VFLILLGIGIYF 365


>gi|209413730 poliovirus receptor isoform gamma [Homo sapiens]
          Length = 364

 Score =  335 bits (860), Expect = 4e-92
 Identities = 183/353 (51%), Positives = 232/353 (65%), Gaps = 19/353 (5%)

Query: 19  WPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCHL-LPPVPGLYISLVTWQR 72
           WPLLL+ LL       G  DV VQ   +V G LG +V LPC+L +P +   ++S +TW R
Sbjct: 9   WPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWAR 68

Query: 73  PDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTV 132
                +   +A FH   GPS+      S+RL FV+A+        AEL++A+L + GL V
Sbjct: 69  HGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG------AELRNASLRMFGLRV 115

Query: 133 EDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPA 192
           EDEGNYTC F TFP+GS     WLRV+AKP+N AE QKV  + +P  +A C+S  GRPPA
Sbjct: 116 EDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPA 175

Query: 193 RISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIP 252
           +I+W S L      +QV G L+GTVTVTS + LVPS + DG  VTCKVEHESFE+P L+ 
Sbjct: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235

Query: 253 VTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGS 312
           V L+V YPPEVSISGYD+NWYLG+ +ATL+CD RSNPEPTGY+WSTT G  P  AVAQG+
Sbjct: 236 VNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGA 295

Query: 313 QLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDVGPLVWGAV 365
           QL+I  VD   NTT +C VTNA+G  +AE  + V+ T  AS    G + + AV
Sbjct: 296 QLLIRPVDKPINTTLICNVTNALGARQAELTVQVKGTEHASASANGHVSYSAV 348


>gi|209413728 poliovirus receptor isoform beta [Homo sapiens]
          Length = 372

 Score =  333 bits (854), Expect = 2e-91
 Identities = 179/338 (52%), Positives = 226/338 (66%), Gaps = 19/338 (5%)

Query: 19  WPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCHL-LPPVPGLYISLVTWQR 72
           WPLLL+ LL       G  DV VQ   +V G LG +V LPC+L +P +   ++S +TW R
Sbjct: 9   WPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWAR 68

Query: 73  PDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTV 132
                +   +A FH   GPS+      S+RL FV+A+        AEL++A+L + GL V
Sbjct: 69  HGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG------AELRNASLRMFGLRV 115

Query: 133 EDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPA 192
           EDEGNYTC F TFP+GS     WLRV+AKP+N AE QKV  + +P  +A C+S  GRPPA
Sbjct: 116 EDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPA 175

Query: 193 RISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIP 252
           +I+W S L      +QV G L+GTVTVTS + LVPS + DG  VTCKVEHESFE+P L+ 
Sbjct: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235

Query: 253 VTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGS 312
           V L+V YPPEVSISGYD+NWYLG+ +ATL+CD RSNPEPTGY+WSTT G  P  AVAQG+
Sbjct: 236 VNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGA 295

Query: 313 QLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP 350
           QL+I  VD   NTT +C VTNA+G  +AE  + V+E P
Sbjct: 296 QLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGP 333


>gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]
          Length = 517

 Score =  213 bits (541), Expect = 4e-55
 Identities = 154/451 (34%), Positives = 220/451 (48%), Gaps = 62/451 (13%)

Query: 30  GAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKM 89
           G     VQV   + G +G  V L C    P+P + I+ VTWQ+     + QNVA ++P M
Sbjct: 27  GVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQK-STNGSKQNVAIYNPSM 85

Query: 90  GPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGS 149
           G S  +P    ER+ F+               D T+ L  L +EDEG Y CEFATFP G+
Sbjct: 86  GVSVLAPY--RERVEFL----------RPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133

Query: 150 VRGMTWLRVIAKPKNQAEAQKVTF-----SQDPTTVALCISKEGRPPARISWLSSLDWEA 204
                 L V+AKP N  E  +          D   VA C S  G+PP+ +SW + L  EA
Sbjct: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEA 193

Query: 205 KETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH--ESFEEPALIPVTLSVRYPPE 262
           +  ++     GTVTV SR+ LVPS  A   ++ C V +  + F+E     +TL+V+Y PE
Sbjct: 194 EYQEIRNP-NGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKES----LTLNVQYEPE 248

Query: 263 VSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHA-VDS 321
           V+I G+D NWYL R D  L+C   +NP  T Y W+T +G+ P    AQ   L     ++ 
Sbjct: 249 VTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINY 308

Query: 322 LFNTTFVCTVTNAVGMGRAEQVIFVRETP-RASP----RDVGPL---VWGAVGGTLLVLL 373
               T++C  TN +G    +  + + E P   SP    R  GP+   + G V G++L++L
Sbjct: 309 SLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGVAGSILLVL 368

Query: 374 LLAGGSLAFILLRVRRRRKSPGGAGGGASGDGGFYDPKAQVLGN-----GDPVFWTPVVP 428
           ++ GG    I++ +RRRR +         GD   Y  K  V GN     G P    P+  
Sbjct: 369 IVVGG----IVVALRRRRHT-------FKGD---YSTKKHVYGNGYSKAGIPQHHPPMAQ 414

Query: 429 GPMEPDGKDEEEE---------EEEEKAEKG 450
               PD  D+E++         EEEE+ E+G
Sbjct: 415 NLQYPDDSDDEKKAGPLGGSSYEEEEEEEEG 445


>gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]
          Length = 458

 Score =  200 bits (509), Expect = 2e-51
 Identities = 144/436 (33%), Positives = 208/436 (47%), Gaps = 38/436 (8%)

Query: 30  GAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKM 89
           G     VQV   + G +G  V L C    P+P + I+ VTWQ+     + QNVA ++P M
Sbjct: 27  GVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQK-STNGSKQNVAIYNPSM 85

Query: 90  GPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGS 149
           G S  +P    ER+ F+               D T+ L  L +EDEG Y CEFATFP G+
Sbjct: 86  GVSVLAPY--RERVEFL----------RPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133

Query: 150 VRGMTWLRVIAKPKNQAEAQKVTF-----SQDPTTVALCISKEGRPPARISWLSSLDWEA 204
                 L V+AKP N  E  +          D   VA C S  G+PP+ +SW + L  EA
Sbjct: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEA 193

Query: 205 KETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH--ESFEEPALIPVTLSVRYPPE 262
           +  ++     GTVTV SR+ LVPS  A   ++ C V +  + F+E     +TL+V+Y PE
Sbjct: 194 EYQEIRNP-NGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKES----LTLNVQYEPE 248

Query: 263 VSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHA-VDS 321
           V+I G+D NWYL R D  L+C   +NP  T Y W+T +G+ P    AQ   L     ++ 
Sbjct: 249 VTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINY 308

Query: 322 LFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDVGPLVWGAVGGTLLVLLLLAGGSLA 381
               T++C  TN +G    +  + + E PR   R +G      + GT+ V L+L      
Sbjct: 309 SLAGTYICEATNPIGTRSGQVEVNITEKPRPQ-RGLGSAA-RLLAGTVAVFLILVAVLTV 366

Query: 382 FILLRVRRRRKSPGGAGGGASGDGGFYDPKAQVLGNGDPVFWTPVVPGPMEPDGKD--EE 439
           F L    R++KSP         DG   D          P   + +VP  ++    D   +
Sbjct: 367 FFL--YNRQQKSP------PETDGAGTDQPLSQKPEPSPSRQSSLVPEDIQVVHLDPGRQ 418

Query: 440 EEEEEEKAEKGLMLPP 455
           +++EEE  +K  + PP
Sbjct: 419 QQQEEEDLQKLSLQPP 434


>gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]
          Length = 352

 Score =  182 bits (463), Expect = 4e-46
 Identities = 115/315 (36%), Positives = 160/315 (50%), Gaps = 26/315 (8%)

Query: 30  GAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKM 89
           G     VQV   + G +G  V L C    P+P + I+ VTWQ+     + QNVA ++P M
Sbjct: 27  GVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQK-STNGSKQNVAIYNPSM 85

Query: 90  GPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGS 149
           G S  +P    ER+ F+               D T+ L  L +EDEG Y CEFATFP G+
Sbjct: 86  GVSVLAPY--RERVEFL----------RPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133

Query: 150 VRGMTWLRVIAKPKNQAEAQKVTF-----SQDPTTVALCISKEGRPPARISWLSSLDWEA 204
                 L V+AKP N  E  +          D   VA C S  G+PP+ +SW + L  EA
Sbjct: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEA 193

Query: 205 KETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH--ESFEEPALIPVTLSVRYPPE 262
           +  ++     GTVTV SR+ LVPS  A   ++ C V +  + F+E     +TL+V+Y PE
Sbjct: 194 EYQEIRNP-NGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKES----LTLNVQYEPE 248

Query: 263 VSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHA-VDS 321
           V+I G+D NWYL R D  L+C   +NP  T Y W+T +G+ P    AQ   L     ++ 
Sbjct: 249 VTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINY 308

Query: 322 LFNTTFVCTVTNAVG 336
               T++C  TN +G
Sbjct: 309 SLAGTYICEATNPIG 323


>gi|11386199 poliovirus receptor-related 3 [Homo sapiens]
          Length = 549

 Score =  157 bits (397), Expect = 2e-38
 Identities = 105/346 (30%), Positives = 165/346 (47%), Gaps = 27/346 (7%)

Query: 13  PPTP-----LLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISL 67
           PPTP     LL+PLLL   L  GA    + V P V    G  V L C +        I+ 
Sbjct: 33  PPTPPPLLLLLFPLLLFSRL-CGALAGPIIVEPHVTAVWGKNVSLKCLI---EVNETITQ 88

Query: 68  VTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLAL 127
           ++W++    ++ Q VA  HP+ G S      G  R+ F +            L DAT+ L
Sbjct: 89  ISWEKIHGKSS-QTVAVHHPQYGFSVQGEYQG--RVLFKNYS----------LNDATITL 135

Query: 128 HGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQA--EAQKVTFSQDPTTVALCIS 185
           H +   D G Y C+  TFP G+ +  T + V+ +P          +    + T  A+CI+
Sbjct: 136 HNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIA 195

Query: 186 KEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESF 245
             G+P A I W   L     E+  +     T T+ S++ L P+  A G  +TC V+H + 
Sbjct: 196 ATGKPVAHIDWEGDLG--EMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPAL 253

Query: 246 EEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPT 305
           E+       L ++Y PEVS++GYD NW++GR    L C+  +NP P    WS   G +P 
Sbjct: 254 EKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPD 313

Query: 306 SAVAQGSQL-VIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP 350
             +A  + L  +H +   ++  ++C VTN++G    ++VI++ + P
Sbjct: 314 GLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPP 359



 Score = 29.3 bits (64), Expect = 8.3
 Identities = 13/20 (65%), Positives = 16/20 (80%)

Query: 460 EDDMESQLDGSLISRRAVYV 479
           EDD+ S +DGS+ISRR  YV
Sbjct: 530 EDDLVSHVDGSVISRREWYV 549


>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
          Length = 510

 Score =  116 bits (290), Expect = 5e-26
 Identities = 107/395 (27%), Positives = 156/395 (39%), Gaps = 47/395 (11%)

Query: 16  PLLWPLLLLLLLE-TGAQDV-RVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRP 73
           P  W LLLLLL   TG      ++    V   LG   +LPC       G  +  V W R 
Sbjct: 12  PEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGD-SGEQVGQVAWARV 70

Query: 74  DAPANHQNVAAFHPKMG----PSFPS----PKPGSERLSFVSAKQSTGQDTEAELQDATL 125
           DA    Q +A  H K G    P++      P P    L                  D ++
Sbjct: 71  DAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPL------------------DGSV 112

Query: 126 ALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCIS 185
            L      DEG Y C  +TFP GS +    LRV+  P                T+A   +
Sbjct: 113 LLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCT 172

Query: 186 KEGRPPARISWLSSLDWEAKETQVSGTL--AGTVTVTSRFTLVPSGRADGVTVTCKVEHE 243
            EG P   ++W    D E K T  S +   + +  VTS F LVPS   +G  +TC V H 
Sbjct: 173 AEGSPAPSVTW----DTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHP 228

Query: 244 SFEEPALIPVTLSVRYPPEVSISGYDDN--WYLGRTDATLSCDVRSNPEPTGYDWSTTSG 301
              +   I   L V +  E S+ G +D   W++GR  A L C     P P+ Y+W+   G
Sbjct: 229 GLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS-YNWTRLDG 287

Query: 302 TFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDV---- 357
             P+     G  L    + +  +  +VC V+N      ++  + V +    S + V    
Sbjct: 288 PLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVS 347

Query: 358 -GPLVWGAVGGTLLVLLLLAGGSLAFILLRVRRRR 391
              +V G +   L  LL++    +  ++ R  RR+
Sbjct: 348 ASVVVVGVIAALLFCLLVV----VVVLMSRYHRRK 378


>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
           sapiens]
          Length = 414

 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 75/291 (25%), Positives = 117/291 (40%), Gaps = 7/291 (2%)

Query: 105 FVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKN 164
           F   K S  Q       +  ++L  +++ DEG Y C+  T P       T + V+  P+N
Sbjct: 89  FRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQE--SYTTITVLVPPRN 146

Query: 165 -QAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRF 223
              + QK T  +       C +   +P   I W    + E K        +   TVTS+ 
Sbjct: 147 LMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKG-NTELKGKSEVEEWSDMYTVTSQL 205

Query: 224 TLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSIS-GYDDNWYLGRTDAT-L 281
            L      DGV V C+VEH +          L V+Y P+V I   Y         DA  L
Sbjct: 206 MLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALEL 265

Query: 282 SCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
           +C+    P+P    W       P  AV  G  L I+ ++   N T+ C  +N VG   ++
Sbjct: 266 TCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSD 325

Query: 342 QVIFVRETPRASPRDVGPLVWGAVGGTLLVLLLLAGGSLAFILLRVRRRRK 392
            +++V ++       +  +    +GG + V ++ A   L  IL R   R K
Sbjct: 326 YMLYVYDSRAGEEGSIRAVDHAVIGGVVAV-VVFAMLCLLIILGRYFARHK 375


>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
           sapiens]
          Length = 442

 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 67/253 (26%), Positives = 102/253 (40%), Gaps = 6/253 (2%)

Query: 105 FVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKN 164
           F   K S  Q       +  ++L  +++ DEG Y C+  T P       T + V+  P+N
Sbjct: 89  FRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQE--SYTTITVLVPPRN 146

Query: 165 -QAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRF 223
              + QK T  +       C +   +P   I W    + E K        +   TVTS+ 
Sbjct: 147 LMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKG-NTELKGKSEVEEWSDMYTVTSQL 205

Query: 224 TLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSIS-GYDDNWYLGRTDAT-L 281
            L      DGV V C+VEH +          L V+Y P+V I   Y         DA  L
Sbjct: 206 MLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALEL 265

Query: 282 SCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
           +C+    P+P    W       P  AV  G  L I+ ++   N T+ C  +N VG   ++
Sbjct: 266 TCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSD 325

Query: 342 QVIFVRETPRASP 354
            +++V + P   P
Sbjct: 326 YMLYVYDPPTTIP 338


>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
          Length = 437

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 67/240 (27%), Positives = 101/240 (42%), Gaps = 11/240 (4%)

Query: 118 AELQDATLALHGLTVEDEGNYTCEFATFP-KGSVRGMTWLRVIAKPKNQAEAQKVTFSQD 176
           A   + ++++  +++ DEG YTC   T P K S   +T L V  KP+    +  V   + 
Sbjct: 84  ASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVM--EG 141

Query: 177 PTTVALCISKEGRPPARISWLSSLDWEAKETQV---SGTLAGTVTVTSRFTLVPSGRADG 233
                 C +   +P A I W  + D E K+ +          T TV+S          DG
Sbjct: 142 DLMQLTCKTSGSKPAADIRWFKN-DKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDG 200

Query: 234 VTVTCKVEHESFE-EPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPT 292
           V V C+V+HES    P +    L + Y P V I         G+    L+C+ +  P P 
Sbjct: 201 VAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQ-PLILTCESKGKPLPE 259

Query: 293 GYDWSTTSGTF--PTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP 350
              W+   G    P   V  G +L I  ++   N T+ C  TN +G   AE V+ V + P
Sbjct: 260 PVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319


>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
          Length = 398

 Score = 76.6 bits (187), Expect = 5e-14
 Identities = 68/270 (25%), Positives = 116/270 (42%), Gaps = 9/270 (3%)

Query: 122 DATLALHGLTVEDEGNYTCEFATFPKGSVRGM-TWLRVIAKPKNQAEAQKVTFSQDPTTV 180
           + ++++  + + DEG YTC   T P  + + + T L +  KP       K +  +  T  
Sbjct: 92  ELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI--ITGYKSSLREKDTAT 149

Query: 181 ALCISKEGRPPARISWLSS-LDWEAKETQVSGTLAG-TVTVTSRFTLVPSGRADGVTVTC 238
             C S   +P AR++W     +   + T++     G T TV+S  T   +   DG ++ C
Sbjct: 150 LNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVC 209

Query: 239 KVEHESFE-EPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWS 297
            V HES +         + V Y P   I     +   G+    L C+ R NP P  Y W 
Sbjct: 210 SVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWE 268

Query: 298 TTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRE-TPRASPRD 356
              G+ P   + Q S L+   ++   + T+ CT T+ +G  +A   + V + +P  S   
Sbjct: 269 -KEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSS 327

Query: 357 VGPLVWGAVGGTLLVLLLLAGGSLAFILLR 386
               + G +   ++ LLL+    L   L+R
Sbjct: 328 TYHAIIGGIVAFIVFLLLIMLIFLGHYLIR 357


>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
          Length = 432

 Score = 76.6 bits (187), Expect = 5e-14
 Identities = 68/270 (25%), Positives = 116/270 (42%), Gaps = 9/270 (3%)

Query: 122 DATLALHGLTVEDEGNYTCEFATFPKGSVRGM-TWLRVIAKPKNQAEAQKVTFSQDPTTV 180
           + ++++  + + DEG YTC   T P  + + + T L +  KP       K +  +  T  
Sbjct: 126 ELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI--ITGYKSSLREKDTAT 183

Query: 181 ALCISKEGRPPARISWLSS-LDWEAKETQVSGTLAG-TVTVTSRFTLVPSGRADGVTVTC 238
             C S   +P AR++W     +   + T++     G T TV+S  T   +   DG ++ C
Sbjct: 184 LNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVC 243

Query: 239 KVEHESFE-EPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWS 297
            V HES +         + V Y P   I     +   G+    L C+ R NP P  Y W 
Sbjct: 244 SVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWE 302

Query: 298 TTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRE-TPRASPRD 356
              G+ P   + Q S L+   ++   + T+ CT T+ +G  +A   + V + +P  S   
Sbjct: 303 -KEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSS 361

Query: 357 VGPLVWGAVGGTLLVLLLLAGGSLAFILLR 386
               + G +   ++ LLL+    L   L+R
Sbjct: 362 TYHAIIGGIVAFIVFLLLIMLIFLGHYLIR 391


>gi|21686977 cell adhesion molecule 4 [Homo sapiens]
          Length = 388

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 85/365 (23%), Positives = 126/365 (34%), Gaps = 45/365 (12%)

Query: 19  WPLLLLLLLETG---AQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDA 75
           WPLLLL     G    Q+V+ +    V    GG  E+ C L                   
Sbjct: 9   WPLLLLWAAAAGPGAGQEVQTE---NVTVAEGGVAEITCRL------------------- 46

Query: 76  PANHQNVAAFHPKMGPSFPSPKPGSERLSFVSA---KQSTGQDTEAELQDATLALHGLTV 132
                     H   G       P  + L F      K    Q  E   +   + L    +
Sbjct: 47  ----------HQYDGSIVVIQNPARQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARL 96

Query: 133 EDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPA 192
           EDEG Y C+  T  + +   +  L V+  P+N     +    +       C+    RP A
Sbjct: 97  EDEGGYFCQLYT--EDTHHQIATLTVLVAPENPVVEVREQAVEGGEVELSCLVPRSRPAA 154

Query: 193 RISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEE--PAL 250
            + W      E K    S       +V S        + DG  + C+ ++++        
Sbjct: 155 TLRWYRDRK-ELKGVSSSQENGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQ 213

Query: 251 IPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQ 310
               L V+Y P   I         G T   L+C V  NP P    W+  + + P  A A 
Sbjct: 214 TQYVLDVQYSPTARIHASQAVVREGDT-LVLTCAVTGNPRPNQIRWNRGNESLPERAEAV 272

Query: 311 GSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDVGPLVWGAVGGTLL 370
           G  L +  + S  N T+ C  +N  G  RA  V+ V + P A       + +  VGG L 
Sbjct: 273 GETLTLPGLVSADNGTYTCEASNKHGHARALYVLVVYD-PGAVVEAQTSVPYAIVGGILA 331

Query: 371 VLLLL 375
           +L+ L
Sbjct: 332 LLVFL 336


>gi|145275174 kin of IRRE-like 2 isoform c [Homo sapiens]
          Length = 708

 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 93/355 (26%), Positives = 131/355 (36%), Gaps = 57/355 (16%)

Query: 20  PLLLLLLL----ETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDA 75
           P LL+LL       G     +Q   ++   LG    LPC L     G Y  LV W +   
Sbjct: 7   PALLVLLFCFRGRAGPSPHFLQQPEDLVVLLGEEARLPCAL-----GAYWGLVQWTKSGL 61

Query: 76  PANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDE 135
               Q                 PG  R  ++S   + GQ          L +  + +EDE
Sbjct: 62  ALGGQR--------------DLPGWSRY-WISGNAANGQHD--------LHIRPVELEDE 98

Query: 136 GNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVA------LCISK-EG 188
            +Y C+      G       L V+  P    EA +V      + VA       C S+ + 
Sbjct: 99  ASYECQATQ--AGLRSRPAQLHVLVPP----EAPQVLGGPSVSLVAGVPANLTCRSRGDA 152

Query: 189 RPPARISWLSS---LDWEA-KETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHES 244
           RP   + W      LD     +T +     G+V  T   TL P    DG T  C+   ++
Sbjct: 153 RPTPELLWFRDGVLLDGATFHQTLLKEGTPGSVEST--LTLTPFSHDDGATFVCRARSQA 210

Query: 245 FEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFP 304
                   +TLS++YPPEV++S        G     L C   + P  TGY W+   G  P
Sbjct: 211 LPTGRDTAITLSLQYPPEVTLSASPHTVQEGEKVIFL-CQATAQPPVTGYRWA--KGGSP 267

Query: 305 TSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP--RASPRDV 357
               A+G +L + A  S       C V+NAVG       + V   P  +A P  V
Sbjct: 268 VLG-ARGPRLEVVADASFLTEPVSCEVSNAVGSANRSTALDVLFGPILQAKPEPV 321



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 63/259 (24%), Positives = 94/259 (36%), Gaps = 51/259 (19%)

Query: 148 GSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKET 207
           GS    T L V+  P  QA+ + V+          C  + G P  R++W           
Sbjct: 298 GSANRSTALDVLFGPILQAKPEPVSVDVGEDASFSCAWR-GNPLPRVTWTRR-------- 348

Query: 208 QVSGTLAGTVTVTSRFTL-VPS-GRADGVTVTCKVEHE-SFEEPALIPVTLSVRYPPEVS 264
                  G   + S  TL +PS G  D     C+ E   S          L+V  PP V+
Sbjct: 349 ------GGAQVLGSGATLRLPSVGPEDAGDYVCRAEAGLSGLRGGAAEARLTVNAPPVVT 402

Query: 265 ISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSG-------------TFPT----SA 307
                  +  G   A L C V ++P P    WS   G             TFP       
Sbjct: 403 ALHSAPAFLRG--PARLQCLVFASPAPDAVVWSWDEGFLEAGSQGRFLVETFPAPESRGG 460

Query: 308 VAQGSQLVIH---AVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDVGP---LV 361
           +  G   V+H     +S F+ +F C+  N +G G A+  +          RD+ P   +V
Sbjct: 461 LGPGLISVLHISGTQESDFSRSFNCSARNRLGEGGAQASL--------GRRDLLPTVRIV 512

Query: 362 WGAVGGTLLVLLLLAGGSL 380
            G    T  +L+++ G +L
Sbjct: 513 AGVAAATTTLLMVITGVAL 531


>gi|145275170 kin of IRRE-like 2 isoform a [Homo sapiens]
          Length = 633

 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 93/355 (26%), Positives = 131/355 (36%), Gaps = 57/355 (16%)

Query: 20  PLLLLLLL----ETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDA 75
           P LL+LL       G     +Q   ++   LG    LPC L     G Y  LV W +   
Sbjct: 7   PALLVLLFCFRGRAGPSPHFLQQPEDLVVLLGEEARLPCAL-----GAYWGLVQWTKSGL 61

Query: 76  PANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDE 135
               Q                 PG  R  ++S   + GQ          L +  + +EDE
Sbjct: 62  ALGGQR--------------DLPGWSRY-WISGNAANGQHD--------LHIRPVELEDE 98

Query: 136 GNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVA------LCISK-EG 188
            +Y C+      G       L V+  P    EA +V      + VA       C S+ + 
Sbjct: 99  ASYECQATQ--AGLRSRPAQLHVLVPP----EAPQVLGGPSVSLVAGVPANLTCRSRGDA 152

Query: 189 RPPARISWLSS---LDWEA-KETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHES 244
           RP   + W      LD     +T +     G+V  T   TL P    DG T  C+   ++
Sbjct: 153 RPTPELLWFRDGVLLDGATFHQTLLKEGTPGSVEST--LTLTPFSHDDGATFVCRARSQA 210

Query: 245 FEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFP 304
                   +TLS++YPPEV++S        G     L C   + P  TGY W+   G  P
Sbjct: 211 LPTGRDTAITLSLQYPPEVTLSASPHTVQEGEKVIFL-CQATAQPPVTGYRWA--KGGSP 267

Query: 305 TSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP--RASPRDV 357
               A+G +L + A  S       C V+NAVG       + V   P  +A P  V
Sbjct: 268 VLG-ARGPRLEVVADASFLTEPVSCEVSNAVGSANRSTALDVLFGPILQAKPEPV 321



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 63/259 (24%), Positives = 94/259 (36%), Gaps = 51/259 (19%)

Query: 148 GSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKET 207
           GS    T L V+  P  QA+ + V+          C  + G P  R++W           
Sbjct: 298 GSANRSTALDVLFGPILQAKPEPVSVDVGEDASFSCAWR-GNPLPRVTWTRR-------- 348

Query: 208 QVSGTLAGTVTVTSRFTL-VPS-GRADGVTVTCKVEHE-SFEEPALIPVTLSVRYPPEVS 264
                  G   + S  TL +PS G  D     C+ E   S          L+V  PP V+
Sbjct: 349 ------GGAQVLGSGATLRLPSVGPEDAGDYVCRAEAGLSGLRGGAAEARLTVNAPPVVT 402

Query: 265 ISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSG-------------TFPT----SA 307
                  +  G   A L C V ++P P    WS   G             TFP       
Sbjct: 403 ALHSAPAFLRG--PARLQCLVFASPAPDAVVWSWDEGFLEAGSQGRFLVETFPAPESRGG 460

Query: 308 VAQGSQLVIH---AVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDVGP---LV 361
           +  G   V+H     +S F+ +F C+  N +G G A+  +          RD+ P   +V
Sbjct: 461 LGPGLISVLHISGTQESDFSRSFNCSARNRLGEGGAQASL--------GRRDLLPTVRIV 512

Query: 362 WGAVGGTLLVLLLLAGGSL 380
            G    T  +L+++ G +L
Sbjct: 513 AGVAAATTTLLMVITGVAL 531


>gi|145275172 kin of IRRE-like 2 isoform b [Homo sapiens]
          Length = 583

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 68/246 (27%), Positives = 98/246 (39%), Gaps = 25/246 (10%)

Query: 125 LALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVA--- 181
           L +  + +EDE +Y C+      G       L V+  P    EA +V      + VA   
Sbjct: 38  LHIRPVELEDEASYECQATQ--AGLRSRPAQLHVLVPP----EAPQVLGGPSVSLVAGVP 91

Query: 182 ---LCISK-EGRPPARISWLSS---LDWEA-KETQVSGTLAGTVTVTSRFTLVPSGRADG 233
               C S+ + RP   + W      LD     +T +     G+V  T   TL P    DG
Sbjct: 92  ANLTCRSRGDARPTPELLWFRDGVLLDGATFHQTLLKEGTPGSVEST--LTLTPFSHDDG 149

Query: 234 VTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTG 293
            T  C+   ++        +TLS++YPPEV++S        G     L C   + P  TG
Sbjct: 150 ATFVCRARSQALPTGRDTAITLSLQYPPEVTLSASPHTVQEGEKVIFL-CQATAQPPVTG 208

Query: 294 YDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP--R 351
           Y W+   G  P    A+G +L + A  S       C V+NAVG       + V   P  +
Sbjct: 209 YRWA--KGGSPVLG-ARGPRLEVVADASFLTEPVSCEVSNAVGSANRSTALDVLFGPILQ 265

Query: 352 ASPRDV 357
           A P  V
Sbjct: 266 AKPEPV 271



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 63/259 (24%), Positives = 94/259 (36%), Gaps = 51/259 (19%)

Query: 148 GSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKET 207
           GS    T L V+  P  QA+ + V+          C  + G P  R++W           
Sbjct: 248 GSANRSTALDVLFGPILQAKPEPVSVDVGEDASFSCAWR-GNPLPRVTWTRR-------- 298

Query: 208 QVSGTLAGTVTVTSRFTL-VPS-GRADGVTVTCKVEHE-SFEEPALIPVTLSVRYPPEVS 264
                  G   + S  TL +PS G  D     C+ E   S          L+V  PP V+
Sbjct: 299 ------GGAQVLGSGATLRLPSVGPEDAGDYVCRAEAGLSGLRGGAAEARLTVNAPPVVT 352

Query: 265 ISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSG-------------TFPT----SA 307
                  +  G   A L C V ++P P    WS   G             TFP       
Sbjct: 353 ALHSAPAFLRG--PARLQCLVFASPAPDAVVWSWDEGFLEAGSQGRFLVETFPAPESRGG 410

Query: 308 VAQGSQLVIH---AVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDVGP---LV 361
           +  G   V+H     +S F+ +F C+  N +G G A+  +          RD+ P   +V
Sbjct: 411 LGPGLISVLHISGTQESDFSRSFNCSARNRLGEGGAQASL--------GRRDLLPTVRIV 462

Query: 362 WGAVGGTLLVLLLLAGGSL 380
            G    T  +L+++ G +L
Sbjct: 463 AGVAAATTTLLMVITGVAL 481


>gi|94538343 sialic acid binding Ig-like lectin 8 [Homo sapiens]
          Length = 499

 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 62/242 (25%), Positives = 86/242 (35%), Gaps = 30/242 (12%)

Query: 186 KEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSR-FTLVPSGRADGVTVTCKVEHES 244
           K+G PP  ISW+ +          S +  G  T  S   TL P  +  G ++TC+V    
Sbjct: 182 KQGTPPM-ISWIGA----------SVSSPGPTTARSSVLTLTPKPQDHGTSLTCQVTLPG 230

Query: 245 FEEPALIPVTLSVRYPP--------------EVSISGYDDNWYLGRTDATLSCDVRSNPE 290
                   V L V YPP                ++        L      L C V SNP 
Sbjct: 231 TGVTTTSTVRLDVSYPPWNLTMTVFQGDATASTALGNGSSLSVLEGQSLRLVCAVNSNP- 289

Query: 291 PTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP 350
           P    W+  S T   S  +    L +  V       F C   NA G       + ++   
Sbjct: 290 PARLSWTRGSLTLCPSRSSNPGLLELPRVHVRDEGEFTCRAQNAQGSQHISLSLSLQNEG 349

Query: 351 RASPRDVGPLVWGAVGGTLLVLLLLAGGSLAFILLRVRRRRKSPGGAGGGASGDGGFYDP 410
             + R V  +   AVGG     L      + FI++R  R++ +   AG    GD G  D 
Sbjct: 350 TGTSRPVSQVTLAAVGGAGATALAFLSFCIIFIIVRSCRKKSARPAAG---VGDTGMEDA 406

Query: 411 KA 412
           KA
Sbjct: 407 KA 408


>gi|90903245 CD200 antigen isoform b [Homo sapiens]
          Length = 294

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 58/226 (25%), Positives = 85/226 (37%), Gaps = 25/226 (11%)

Query: 17  LLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAP 76
           L+W +  ++L     Q     V  + R QL     L C L      L   +VTWQ+  A 
Sbjct: 43  LVWVMAAVVLCTAQVQ----VVTQDEREQLYTPASLKCSLQNAQEAL---IVTWQKKKA- 94

Query: 77  ANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEG 136
            + +N+  F    G            +    A +     T+  LQ++T+    +T+EDEG
Sbjct: 95  VSPENMVTFSENHG------------VVIQPAYKDKINITQLGLQNSTITFWNITLEDEG 142

Query: 137 NYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPARISW 196
            Y C F TF  G + G   L V  +P     +    FS+D   +    S   RP   + W
Sbjct: 143 CYMCLFNTFGFGKISGTACLTVYVQP---IVSLHYKFSEDHLNIT--CSATARPAPMVFW 197

Query: 197 LSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH 242
                     T       GT +VTS   +       G  V C+V H
Sbjct: 198 KVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKEVICQVLH 243


>gi|90903247 CD200 antigen isoform a precursor [Homo sapiens]
          Length = 269

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 58/226 (25%), Positives = 85/226 (37%), Gaps = 25/226 (11%)

Query: 17  LLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAP 76
           L+W +  ++L     Q     V  + R QL     L C L      L   +VTWQ+  A 
Sbjct: 18  LVWVMAAVVLCTAQVQ----VVTQDEREQLYTPASLKCSLQNAQEAL---IVTWQKKKA- 69

Query: 77  ANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEG 136
            + +N+  F    G            +    A +     T+  LQ++T+    +T+EDEG
Sbjct: 70  VSPENMVTFSENHG------------VVIQPAYKDKINITQLGLQNSTITFWNITLEDEG 117

Query: 137 NYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPARISW 196
            Y C F TF  G + G   L V  +P     +    FS+D   +    S   RP   + W
Sbjct: 118 CYMCLFNTFGFGKISGTACLTVYVQP---IVSLHYKFSEDHLNIT--CSATARPAPMVFW 172

Query: 197 LSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH 242
                     T       GT +VTS   +       G  V C+V H
Sbjct: 173 KVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKEVICQVLH 218


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 58/240 (24%), Positives = 97/240 (40%), Gaps = 27/240 (11%)

Query: 120  LQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTT 179
            L   +L +  +   D G+YTC  A    GS    T L V   P+ ++     T +++   
Sbjct: 4128 LSSGSLQIAFVQPGDAGHYTCMAANVA-GSSSTSTKLTVHVPPRIRSTEGHYTVNENSQA 4186

Query: 180  VALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRA--DGVTVT 237
            +  C++ +G P   I+W        K+  +   L G  T      L+       D    T
Sbjct: 4187 ILPCVA-DGIPTPAINW-------KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYT 4238

Query: 238  CKVEHESFEEPALIPVTLSV-----RYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPT 292
            C   + + E+   + +T+ V       P +VS++  +           LSC     P P 
Sbjct: 4239 CVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQ--------LRLSCKATGIPLPK 4290

Query: 293  GYDWSTTSGTFPT--SAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP 350
               W+  +   P    +V   S+LVI  V    + T+VCT  N+VG  +A   ++V+E P
Sbjct: 4291 -LTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 69/272 (25%), Positives = 108/272 (39%), Gaps = 28/272 (10%)

Query: 122 DATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVA 181
           D TL +     +D G Y C  A+   G+ +  + LR I  PK      ++  +    TV 
Sbjct: 663 DGTLFIKNAAPKDAGIYGC-LASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVM 721

Query: 182 LCISKEGRPPARISWLSS-LDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV 240
            C    G PP ++ W    L+       +   L G + +     L      D    TC  
Sbjct: 722 EC-KTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDL------DAGDYTCVA 774

Query: 241 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTT- 299
            +E+    A   +TL V  PP       D +  +G ++ TL C V+  PEPT   W    
Sbjct: 775 INEAGR--ATGKITLDVGSPPVFIQEPADVSMEIG-SNVTLPCYVQGYPEPT-IKWRRLD 830

Query: 300 -----SGTFPTSAVAQ---GSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPR 351
                S  F  S+++Q   G+  +++   S    T++C   N  G  ++E  + V  T  
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWAS-DKGTYICEAENQFGKIQSETTVTV--TGL 887

Query: 352 ASPR-DVGPLVWGAVGGTLLVL--LLLAGGSL 380
            +P   + P V   + G  L L   LLAG  +
Sbjct: 888 VAPLIGISPSVANVIEGQQLTLPCTLLAGNPI 919



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 56/242 (23%), Positives = 93/242 (38%), Gaps = 30/242 (12%)

Query: 123  ATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPK---NQAEAQKVTFSQDPTT 179
            +TL ++G    D G YTC  AT P G    +  L V   P    N+ EA+K+    D T+
Sbjct: 3302 STLNIYGALTSDTGKYTC-VATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVD-TS 3359

Query: 180  VALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCK 239
            + +     G PP +I+WL +       + +    AG V       +V +  +D    TC 
Sbjct: 3360 INIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQV-----IRIVRAQVSDVAVYTCV 3414

Query: 240  VEHESFEEPALIPVTLSVRYPPEVSIS-GYDDNWYLGRTDATLSCDVRSNP--------- 289
              + +  +       L V  PP +  S G ++   L  +  +++C     P         
Sbjct: 3415 ASNRAGVDNK--HYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRD 3472

Query: 290  -EPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRE 348
             +P G D   T  T        G  L +   ++  +  + C  +N  G      ++ V E
Sbjct: 3473 GQPLGLDAHLTVST-------HGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLE 3525

Query: 349  TP 350
             P
Sbjct: 3526 PP 3527



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 79/328 (24%), Positives = 118/328 (35%), Gaps = 41/328 (12%)

Query: 38   VLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPK 97
            V   V G    T  +  H+LP +      L T +    P      A+ +PK  PS    K
Sbjct: 961  VASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIE--GIPVTLPCKASGNPK--PSVIWSK 1016

Query: 98   PGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLR 157
             G E +S  SAK S G D        +L +     E+ G Y C  AT   G  +    L 
Sbjct: 1017 KG-ELISTSSAKFSAGAD-------GSLYVVSPGGEESGEYVCT-ATNTAGYAKRKVQLT 1067

Query: 158  VIAKPKNQAEAQKVTFSQD-PTTVALCISKEGRPPARISWLSS--LDWEAKETQVSGTLA 214
            V  +P+   + + +  SQD P  +++   +E   P  +  L    + W AKETQ+    +
Sbjct: 1068 VYVRPRVFGDQRGL--SQDKPVEISVLAGEEVTLPCEVKSLPPPIITW-AKETQLISPFS 1124

Query: 215  GTVTVTSRFTLVPSGR--------ADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSIS 266
                   R T +PSG         +D     C   + +        V L+V  PP++   
Sbjct: 1125 ------PRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQA--VKLNVHVPPKIQRG 1176

Query: 267  GYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQ----LVIHAVDSL 322
                   +G+    + C+ +  P P    WS    T         S     L I      
Sbjct: 1177 PKHLKVQVGQR-VDIPCNAQGTPLPV-ITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS 1234

Query: 323  FNTTFVCTVTNAVGMGRAEQVIFVRETP 350
                + C  TN  G    E  + V+E P
Sbjct: 1235 DAGIYTCVATNIAGTDETEITLHVQEPP 1262



 Score = 37.7 bits (86), Expect = 0.023
 Identities = 78/343 (22%), Positives = 120/343 (34%), Gaps = 70/343 (20%)

Query: 25   LLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAA 84
            + L+ G+  V +Q   +V  ++G  V LPC+    V G     + W+R D      N+  
Sbjct: 785  ITLDVGSPPVFIQEPADVSMEIGSNVTLPCY----VQGYPEPTIKWRRLD------NMPI 834

Query: 85   FHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFAT 144
            F              S   S  S  Q         L+   L +  L   D+G Y CE A 
Sbjct: 835  F--------------SRPFSVSSISQ---------LRTGALFILNLWASDKGTYICE-AE 870

Query: 145  FPKGSVRGMTWLRVIA----------KPKNQAEAQKVTFSQDPTTVALCISKEGRPPARI 194
               G ++  T + V               N  E Q++T          C    G P    
Sbjct: 871  NQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLP--------CTLLAGNPIPER 922

Query: 195  SWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIPVT 254
             W+ +     +   ++    G++ +  R  L      DG   TC   + +        V 
Sbjct: 923  RWIKNSAMLLQNPYITVRSDGSLHI-ERVQL-----QDGGEYTCVASNVAGTNNKTTSVV 976

Query: 255  LSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPT------GYDWSTTSGTFPTSAV 308
            + V   P +   G      +     TL C    NP+P+      G   ST+S  F  SA 
Sbjct: 977  VHVL--PTIQ-HGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKF--SAG 1031

Query: 309  AQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPR 351
            A GS  V+ +     +  +VCT TN  G  + +  + V   PR
Sbjct: 1032 ADGSLYVV-SPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPR 1073



 Score = 35.8 bits (81), Expect = 0.088
 Identities = 55/236 (23%), Positives = 87/236 (36%), Gaps = 23/236 (9%)

Query: 125  LALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCI 184
            LAL    + D G YTC  A    G  +    LRV   P    E Q V+         LC 
Sbjct: 2068 LALTSAQISDTGRYTC-VAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQ 2126

Query: 185  SKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHES 244
            S +  PP  ++WL       K+  +S +   +V       +  +GR      TC+  + +
Sbjct: 2127 S-DAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGR-----YTCEATNVA 2180

Query: 245  FEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDA---TLSCDVRSNPEPTGYDWSTTSG 301
             +      V + V  PP  +I G D+   L   +    +L C+    P P    W     
Sbjct: 2181 GKTEKNYNVNIWV--PP--NIGGSDELTQLTVIEGNLISLLCESSGIP-PPNLIWKKKGS 2235

Query: 302  TFPTSAVAQ------GSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQ--VIFVRET 349
               T ++ +      G QL I   +      + C  +N  G  + E    +++R T
Sbjct: 2236 PVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPT 2291



 Score = 35.8 bits (81), Expect = 0.088
 Identities = 46/175 (26%), Positives = 67/175 (38%), Gaps = 21/175 (12%)

Query: 125  LALHGLTVEDEGNYTCEFATFPKGSVRGMTW----LRVIAKPK---NQAEAQKVTFSQDP 177
            L L  + V D G Y C        +V GMT     L V A P    N    + ++  +  
Sbjct: 2348 LQLKNIHVSDTGRYVCVAV-----NVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK- 2401

Query: 178  TTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVT 237
             +V+L     G P   I+W     W    +     L+G         L+ +   D    T
Sbjct: 2402 NSVSLTCEASGIPLPSITWFKD-GWPVSLSNSVRILSGG----RMLRLMQTTMEDAGQYT 2456

Query: 238  CKVEHESFEEPALIPVTLSVRYPPE-VSISGYDDNWYLGRTDATLSCDVRSNPEP 291
            C V + + EE  +    LSV  PP  V  +  +D     +   TL+C+V  NP P
Sbjct: 2457 CVVRNAAGEERKIFG--LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 52/237 (21%), Positives = 82/237 (34%), Gaps = 33/237 (13%)

Query: 132  VEDEGNYTCEFATFPKGSVRGMTWLRVIAKPK--NQAEAQKVTFSQDPTTVALCISKEGR 189
            VED G YTC  A+ P G       +RV   P      E + +T  ++      C S +  
Sbjct: 3591 VEDTGRYTC-LASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKS-DAV 3648

Query: 190  PPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGR---------ADGVTVTCKV 240
            PP  I+WL + +               +  T R  ++  GR          D    TC  
Sbjct: 3649 PPPVITWLRNGE--------------RLQATPRVRILSGGRYLQINNADLGDTANYTCVA 3694

Query: 241  EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPT---GYDWS 297
             + + +      +T++V  PP +   G      L      L C     P P      D +
Sbjct: 3695 SNIAGKTTREFILTVNV--PPNIK-GGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGA 3751

Query: 298  TTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASP 354
              +G     ++ +   L I +        ++C  TNA G  R    + V   P  +P
Sbjct: 3752 VLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAP 3808



 Score = 34.3 bits (77), Expect = 0.26
 Identities = 52/214 (24%), Positives = 76/214 (35%), Gaps = 18/214 (8%)

Query: 132  VEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPP 191
            V D G Y C  A    G       L V   P  +   ++V        V L     G PP
Sbjct: 3122 VSDTGQYVCR-AINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPP 3180

Query: 192  ARISWLSSLDWEAKETQVSGTL-AGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPAL 250
              I+WL +     K  + S +L    ++  S+  +  S  +D    TC     + E  A 
Sbjct: 3181 PTIAWLKN----HKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIA--SNMEGKAQ 3234

Query: 251  IPVTLSVRYPPEVSISGY--DDNWYLGRTDATLSCDVRSNPEPTGYDW------STTSGT 302
                LS++ PP V+ +    D +  LG  +  L C+    P P    W        +  T
Sbjct: 3235 KYYFLSIQVPPSVAGAEIPSDVSVLLGE-NVELVCNANGIPTPL-IQWLKDGKPIASGET 3292

Query: 303  FPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVG 336
                  A GS L I+   +     + C  TN  G
Sbjct: 3293 ERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326



 Score = 33.5 bits (75), Expect = 0.44
 Identities = 57/234 (24%), Positives = 87/234 (37%), Gaps = 25/234 (10%)

Query: 125  LALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCI 184
            L L  + +ED G YTC  A    G       L V   P         TF++ P  V+L  
Sbjct: 4224 LILENVVLEDSGFYTC-VANNAAGEDTHTVSLTVHVLP---------TFTELPGDVSLNK 4273

Query: 185  SKEGRPPARISW--LSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH 242
             ++ R   + +   L  L W      +      +V   S   +    + D  T  C  E+
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNNIIPAHF-DSVNGHSELVIERVSKEDSGTYVCTAEN 4332

Query: 243  ESFEEPALIPVTLSVRYPPEVSISGYDDNWY--LGRTDATLSCDVRSNPEPTGYDWSTTS 300
                  A+  V   V+ PP V    Y  NW   LG  +A L+C+V+ +P PT   W+   
Sbjct: 4333 SVGFVKAIGFVY--VKEPP-VFKGDYPSNWIEPLGG-NAILNCEVKGDPTPT-IQWNRKG 4387

Query: 301  GTFPTS----AVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP 350
                 S     +  GS L I+   +     + C  TN  G+      + ++  P
Sbjct: 4388 VDIEISHRIRQLGNGS-LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440



 Score = 33.1 bits (74), Expect = 0.57
 Identities = 50/242 (20%), Positives = 84/242 (34%), Gaps = 17/242 (7%)

Query: 120  LQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTT 179
            L++  L +    V D G Y C  AT   G+ R    L+V   P        +T   +  T
Sbjct: 3763 LENGFLHIQSAHVTDTGRYLC-MATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQT 3821

Query: 180  VALCISKEGRPPARISWLSS---LDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTV 236
               C    G P   I+W  +   L+ +  +       +G++ + S     PS   D  T 
Sbjct: 3822 TLAC-EATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIIS-----PSVD-DTATY 3874

Query: 237  TCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDW 296
             C V + + ++   + +T+ V  PP ++     D        A ++C     P P+ +  
Sbjct: 3875 ECTVTNGAGDDKRTVDLTVQV--PPSIADEP-TDFLVTKHAPAVITCTASGVPFPSIHWT 3931

Query: 297  STTSGTFPTS---AVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRAS 353
                   P      +     + I A        + C   NA G       + V E P   
Sbjct: 3932 KNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQ 3991

Query: 354  PR 355
            P+
Sbjct: 3992 PQ 3993



 Score = 32.7 bits (73), Expect = 0.75
 Identities = 51/231 (22%), Positives = 83/231 (35%), Gaps = 31/231 (13%)

Query: 122  DATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVA 181
            D +L +  + ++D G YTC  A+   G+    T + V   P  Q   Q++  + +   V 
Sbjct: 942  DGSLHIERVQLQDGGEYTC-VASNVAGTNNKTTSVVVHVLPTIQ-HGQQILSTIEGIPVT 999

Query: 182  LCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVE 241
            L     G P   + W  S   E   T  +   AG     S + + P G   G  V C   
Sbjct: 1000 LPCKASGNPKPSVIW--SKKGELISTSSAKFSAG--ADGSLYVVSPGGEESGEYV-CTAT 1054

Query: 242  HESFEEPALIPVTLSVR-------------YPPEVSISGYDDNWYLGRTDATLSCDVRSN 288
            + +      + +T+ VR              P E+S+        L   + TL C+V+S 
Sbjct: 1055 NTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISV--------LAGEEVTLPCEVKSL 1106

Query: 289  PEPT---GYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVG 336
            P P      +    S   P         + I    +  +  ++C  TN  G
Sbjct: 1107 PPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAG 1157



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 5/95 (5%)

Query: 119  ELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPT 178
            +L + +LA++G   ED G+YTC  AT   G V     L + + P    E  +   +    
Sbjct: 4398 QLGNGSLAIYGTVNEDAGDYTC-VATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGK 4456

Query: 179  TVALCISKEGRPPARISWL---SSLDWEAKETQVS 210
             +  C    G P   I+W     S+ W+ +   +S
Sbjct: 4457 IILNC-QATGEPQPTITWSRQGHSISWDDRVNVLS 4490



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 72/301 (23%), Positives = 106/301 (35%), Gaps = 35/301 (11%)

Query: 2    ARAAALLPSRSPPTPLLWPLLLLLLLETGAQD--VRVQVLPEVRGQLGGTVELPCHLLPP 59
            A+   L+   SP    L P   + + ET   D  + + V   + G +   V+L  H+ P 
Sbjct: 1114 AKETQLISPFSPRHTFL-PSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPK 1172

Query: 60   VPG--LYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTE 117
            +     ++ +   QR D P N Q          P     K GS  L           +  
Sbjct: 1173 IQRGPKHLKVQVGQRVDIPCNAQGTPL------PVITWSKGGSTML--------VDGEHH 1218

Query: 118  AELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKP--KNQAEAQKVTFSQ 175
                D TL++   T  D G YTC  AT   G+      L V   P  ++       TF +
Sbjct: 1219 VSNPDGTLSIDQATPSDAGIYTC-VATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQE 1277

Query: 176  DPTTVAL---CISKEGRPPARISWL-SSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRA 231
                  +   C +K G P   I WL +  +   +E  +S    GT+ V +  T   +G  
Sbjct: 1278 RVANQRIEFPCPAK-GTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEY 1336

Query: 232  DGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDAT-LSCDVRSNPE 290
              V V    E  + E        L V  PP +       N  +     T L C+V   P 
Sbjct: 1337 ICVAVN---EAGTTER----KYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPS 1389

Query: 291  P 291
            P
Sbjct: 1390 P 1390



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 52/242 (21%), Positives = 88/242 (36%), Gaps = 28/242 (11%)

Query: 123  ATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPK--NQAEAQKVTFSQDPTTV 180
            + L +    V+D G YTCE AT   G       + +   P      E  ++T  +     
Sbjct: 2157 SVLKIEDAQVQDTGRYTCE-ATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLIS 2215

Query: 181  ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTS---RFTLVPSGRADGVTVT 237
             LC S    PP       +L W+ K + V     G V + S   +  +  + ++D    +
Sbjct: 2216 LLCESSGIPPP-------NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYS 2268

Query: 238  CKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYL---GRTDATLSCDVRSNPEPT-- 292
            C   + +    A     L V   P ++ SG      +   G++  +L C+V+  P PT  
Sbjct: 2269 CVASNVA--GTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKS-ISLECEVQGIPPPTVT 2325

Query: 293  ----GYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRE 348
                G+      G      + +G  L +  +       +VC   N  GM   +  + V  
Sbjct: 2326 WMKDGHPLIKAKG---VEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHA 2382

Query: 349  TP 350
             P
Sbjct: 2383 PP 2384



 Score = 30.0 bits (66), Expect = 4.8
 Identities = 53/230 (23%), Positives = 81/230 (35%), Gaps = 27/230 (11%)

Query: 120  LQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTT 179
            L   ++ +      D G Y C  AT   G+V     L V   PK Q   + +   Q    
Sbjct: 1130 LPSGSMKITETRTSDSGMYLC-VATNIAGNVTQAVKLNVHVPPKIQRGPKHLKV-QVGQR 1187

Query: 180  VALCISKEGRPPARISWLSS-----LDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGV 234
            V +  + +G P   I+W        +D E   +   GTL+      S          D  
Sbjct: 1188 VDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS----------DAG 1237

Query: 235  TVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDAT----LSCDVRSNPE 290
              TC   + +  +     +TL V+ PP V       N       A       C  +  P+
Sbjct: 1238 IYTCVATNIAGTDET--EITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPK 1295

Query: 291  PTG---YDWSTTSGTFP-TSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVG 336
            PT    ++    +G  P  S +  G+ LVI +V    N  ++C   N  G
Sbjct: 1296 PTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAG 1345



 Score = 30.0 bits (66), Expect = 4.8
 Identities = 38/178 (21%), Positives = 59/178 (33%), Gaps = 13/178 (7%)

Query: 188  GRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEE 247
            G PP  I WL       +       L G   V ++  +  +G    +      +H+   E
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFE 1819

Query: 248  PALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEP--TGYDWSTTSGTFPT 305
                   ++V  PP +  SG  +   +      L C     P P  T         T   
Sbjct: 1820 -------VTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQG 1872

Query: 306  SAVAQGSQLVIHAVDSLFNTT--FVCTVTNAVGMGRAEQVIFVRETPRASPRDVGPLV 361
            +   Q S  V+    +L      + C  TNA G  +    + V E P  S  D G ++
Sbjct: 1873 NLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP--SLEDAGKML 1928


>gi|157739930 TAP binding protein-like [Homo sapiens]
          Length = 468

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 45/139 (32%), Positives = 68/139 (48%), Gaps = 21/139 (15%)

Query: 121 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQA----EAQKVTFSQD 176
           +DA+L L GLT++DEG Y C+  T      + +  L + A PK +     EA   T   D
Sbjct: 264 RDASLTLPGLTIQDEGTYICQITT-SLYRAQQIIQLNIQASPKVRLSLANEALLPTLICD 322

Query: 177 -----PTTVALCISKE--GRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSG 229
                P  V +  ++E  G  PA++S        A  + +  ++AGT +++S  T  P  
Sbjct: 323 IAGYYPLDVVVTWTREELGGSPAQVS-------GASFSSLRQSVAGTYSISSSLTAEPG- 374

Query: 230 RADGVTVTCKVEHESFEEP 248
            + G T TC+V H S EEP
Sbjct: 375 -SAGATYTCQVTHISLEEP 392


>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
           5 preproprotein [Homo sapiens]
          Length = 702

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 67/269 (24%), Positives = 102/269 (37%), Gaps = 28/269 (10%)

Query: 87  PKMGPSFPSPKPGSE-RLSFVSAKQSTGQ-----DTEAELQDATLALHGLTVEDEGNYTC 140
           P + PS+   +PG    LS  +A     Q     D   +     L +  +T ++ G YTC
Sbjct: 418 PTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTC 477

Query: 141 EFATFPKG----SVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPARISW 196
           +      G    +V+ +T    + KP   +   K    +D   VA     E +    + W
Sbjct: 478 QANNSASGHSRTTVKTITVSAELPKPSISSNNSKPV--EDKDAVAFTCEPEAQNTTYLWW 535

Query: 197 LSSLDWEAK-ETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIPVTL 255
           ++          Q+S    G  T+T    L    R D     C +++ S       PVTL
Sbjct: 536 VNGQSLPVSPRLQLSN---GNRTLT----LFNVTRNDARAYVCGIQN-SVSANRSDPVTL 587

Query: 256 SVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLV 315
            V Y P+  I    D+ YL   +  LSC   SNP P  Y W         + V     L 
Sbjct: 588 DVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQ-YSWRINGIPQQHTQV-----LF 641

Query: 316 IHAVDSLFNTTFVCTVTNAVGMGRAEQVI 344
           I  +    N T+ C V+N +  GR   ++
Sbjct: 642 IAKITPNNNGTYACFVSN-LATGRNNSIV 669



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 55/245 (22%), Positives = 93/245 (37%), Gaps = 31/245 (12%)

Query: 124 TLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALC 183
           TL L  +T  D G Y C               L V+  P +   +   T+ +    ++L 
Sbjct: 377 TLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVNLSLS 436

Query: 184 ISKEGRPPARISWL--SSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVE 241
                 PPA+ SWL   ++    +E  +S     T   +  +T   +  A G + T    
Sbjct: 437 CHAASNPPAQYSWLIDGNIQQHTQELFISNI---TEKNSGLYTCQANNSASGHSRT---- 489

Query: 242 HESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSG 301
                   +  +T+S    P+ SIS  +      +     +C+  +  + T Y W     
Sbjct: 490 -------TVKTITVSAEL-PKPSISSNNSKPVEDKDAVAFTCEPEA--QNTTYLWWVNGQ 539

Query: 302 TFPTSAVAQGSQLVIHAVDSLFNTT------FVCTVTNAVGMGRAE----QVIFVRETPR 351
           + P S   Q S    +   +LFN T      +VC + N+V   R++     V++  +TP 
Sbjct: 540 SLPVSPRLQLSN--GNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPI 597

Query: 352 ASPRD 356
            SP D
Sbjct: 598 ISPPD 602



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 42/174 (24%), Positives = 66/174 (37%), Gaps = 10/174 (5%)

Query: 125 LALHGLTVEDEGNYTCEFATFPKGSVRG-MTWLRVIAKP-KNQAEAQKVTFSQDPTTVAL 182
           L +  +TV + G+YTC+      G  R  +T + V A+P K    +      +D   VAL
Sbjct: 284 LFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVAL 343

Query: 183 CISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH 242
               E +    + W+++                T+T+ S           G+     V+H
Sbjct: 344 TCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDH 403

Query: 243 ESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDW 296
                    PV L+V Y P+         +Y    + +LSC   SNP P  Y W
Sbjct: 404 SD-------PVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNP-PAQYSW 449



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 55/284 (19%), Positives = 91/284 (32%), Gaps = 47/284 (16%)

Query: 91  PSFPSPKPGSERLSFVSAKQSTGQDTEAELQDA------------------------TLA 126
           P  P P   S     V  K +     E E QDA                        TL 
Sbjct: 142 PELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLT 201

Query: 127 LHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISK 186
           L  +T  D  +Y CE              L V+  P     +   T  +    + L    
Sbjct: 202 LFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGENLNLSCHA 261

Query: 187 EGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGV-TVTCKVEHESF 245
              PPA+ SW                + GT   +++   +P+   +   + TC+  +   
Sbjct: 262 ASNPPAQYSWF---------------VNGTFQQSTQELFIPNITVNNSGSYTCQAHNSDT 306

Query: 246 EEPALIPVTLSV-RYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFP 304
                   T++V   PP+  I+  + N         L+C+     + T Y W   + + P
Sbjct: 307 GLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCE--PEIQNTTYLWWVNNQSLP 364

Query: 305 TSAVAQGSQ----LVIHAVDSLFNTTFVCTVTNAVGMGRAEQVI 344
            S   Q S     L + +V       + C + N + +  ++ VI
Sbjct: 365 VSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVI 408


>gi|7657570 sialic acid binding Ig-like lectin 7 isoform 1 [Homo
           sapiens]
          Length = 467

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 58/234 (24%), Positives = 92/234 (39%), Gaps = 30/234 (12%)

Query: 186 KEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESF 245
           ++G PP  ISW+         T VS  L  + T +S  TL+P  +  G ++TC+V     
Sbjct: 175 EQGTPPM-ISWMG--------TSVS-PLHPSTTRSSVLTLIPQPQHHGTSLTCQVTLPGA 224

Query: 246 EEPALIPVTLSVRYPPE--------------VSISGYDDNWYLGRTDATLSCDVRSNPEP 291
                  + L+V YPP+               ++        L      L C V SNP P
Sbjct: 225 GVTTNRTIQLNVSYPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNP-P 283

Query: 292 TGYDWSTTSGTFPTSAVAQGS--QLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRET 349
               W+  S T   S  +     +L +H  D      F C   N++G       + +++ 
Sbjct: 284 ARLSWTWRSLTLYPSQPSNPLVLELQVHLGDE---GEFTCRAQNSLGSQHVSLNLSLQQE 340

Query: 350 PRASPRDVGPLVWGAVGGTLLVLLLLAGGSLAFILLRVRRRRKSPGGAGGGASG 403
                R V  ++ GAVGG     L+     + FI++R  R++ +   A  G  G
Sbjct: 341 YTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFIVVRSCRKKSARPAADVGDIG 394


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 63/249 (25%), Positives = 93/249 (37%), Gaps = 22/249 (8%)

Query: 110  QSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKP--KNQAE 167
            Q  G      L   +L L GL   D G YTC  A  P G    +  + V+  P  K  A+
Sbjct: 2069 QDMGPHLRFYLDGGSLVLKGLRASDAGAYTC-VAHNPAGEDARLHTVNVLVPPTIKQGAD 2127

Query: 168  AQKVTFSQDPTTVALCISKEGRPPARISWL-SSLDWE-AKETQVSGTLAGTVTVTSRFTL 225
                  S+    V +     G PP  +SWL   L    ++ T + G  +G     S+  L
Sbjct: 2128 GSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHG--SGHTLRISKVQL 2185

Query: 226  VPSGRADGVTVTCKVEHESFEEPALIP---VTLSVRYPPEVSISGYDDNWYLGRTD-ATL 281
                 AD    TC         PA +     TL V+ PP +    + ++  + R     L
Sbjct: 2186 -----ADAGIFTCVA-----ASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVEL 2235

Query: 282  SCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
             C+ R  P P    W        + ++ QG  L + AV +  + T+ C   +  G  R  
Sbjct: 2236 PCEARGVPLPL-VSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRH 2294

Query: 342  QVIFVRETP 350
              + V E P
Sbjct: 2295 FQLTVMEPP 2303



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 71/276 (25%), Positives = 107/276 (38%), Gaps = 29/276 (10%)

Query: 111  STGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQK 170
            +TG  T+  L    L +   + ED GNY C  A    GS  G T L V   P  +     
Sbjct: 2798 ATGVSTQV-LPGGQLRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIENGLPD 2855

Query: 171  VTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGR 230
            ++ ++       C ++    P       ++ W+     VSG          +FT+ PSG 
Sbjct: 2856 LSTTEGSHAFLPCKARGSPEP-------NITWDKDGQPVSGA-------EGKFTIQPSGE 2901

Query: 231  A--------DGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLS 282
                     D  T TC  E+        + +T+ V  P   ++ G D +  LG     L 
Sbjct: 2902 LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILV-LPVFTTLPG-DRSLRLGDR-LWLR 2958

Query: 283  CDVRSNPEPT-GYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
            C  R +P P  G+  +    T   S    GS L   AV    + T+VC   N VG  +A 
Sbjct: 2959 CAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAV 3018

Query: 342  QVIFVRETPRASPRDVGPLVWGAVGGTLLVLLLLAG 377
              + V+E P         LV   VGG++ +  ++ G
Sbjct: 3019 SFVHVKEAPVLQGEAFSYLV-EPVGGSIQLDCVVRG 3053



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 51/233 (21%), Positives = 88/233 (37%), Gaps = 18/233 (7%)

Query: 125 LALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCI 184
           L +  + + DEG YTC  AT   G  +    L+V+  P  +         ++ +    C+
Sbjct: 659 LQIEKVDLRDEGIYTCA-ATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECL 717

Query: 185 SKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGR-ADGVTVTCKVEHE 243
           +  G PP  +SW            VS  +  TV+V  R   +   + +D  +  C   + 
Sbjct: 718 AS-GVPPPDVSWFKG------HQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNV 770

Query: 244 SFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDW------S 297
           +      +   L V  PP +++        L  T   L+C+    P PT   W       
Sbjct: 771 AGSTE--LRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPT-LMWLKDGNPV 827

Query: 298 TTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP 350
           + +GT        G  L + +  +  +  + C   +AVG  R + V+ V   P
Sbjct: 828 SPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPP 880



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 56/238 (23%), Positives = 89/238 (37%), Gaps = 22/238 (9%)

Query: 124  TLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV--- 180
            TL L    + D G YTCE A    G  + +  L V+  P   A  Q     QD   V   
Sbjct: 1801 TLQLGRARLSDSGMYTCE-ALNAAGRDQKLVQLSVLVPP---AFRQAPRGPQDAVLVRVG 1856

Query: 181  ---ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVT 237
                L    +  P   ++W     ++  +  V       +    R  +  +  +D    +
Sbjct: 1857 DKAVLSCETDALPEPTVTW-----YKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYS 1911

Query: 238  CKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWS 297
            CKV + + E  A+   TL+V+ PP       +    +  +   L+CDV   P PT   W 
Sbjct: 1912 CKVSNVAGE--AVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPT-VTWL 1968

Query: 298  TTSGTFPTSAV----AQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPR 351
                   +SAV    ++G +L +  +      T+ C   N     R + V+ V   PR
Sbjct: 1969 KDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPR 2026



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 56/239 (23%), Positives = 85/239 (35%), Gaps = 18/239 (7%)

Query: 134 DEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQK--VTFSQDPTTVALCISKEGRPP 191
           D G YTC+ A+   G+    T L V   P  +    +  V  +     VAL     G P 
Sbjct: 376 DAGVYTCK-ASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPS 434

Query: 192 ARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALI 251
             +SW       A+  +      G+V       L   G A     +C     + E  A++
Sbjct: 435 PTLSWHHEGLPVAESNESRLETDGSV-----LRLESPGEASSGLYSCVASSPAGE--AVL 487

Query: 252 PVTLSVRYPPEVSIS-GYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSA--- 307
             ++ V+ PP++ ++ G      +      L C    +P PT   W          A   
Sbjct: 488 QYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPT-IQWLQNGRPAEELAGVQ 546

Query: 308 -VAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRE--TPRASPRDVGPLVWG 363
             +QG+ L I  V+   +  F C  TN  G   AE  + V     P      +G   WG
Sbjct: 547 VASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWG 605



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 41/179 (22%), Positives = 65/179 (36%), Gaps = 9/179 (5%)

Query: 114  QDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTF 173
            Q T+A      L +    V D+G Y+C+ +     +VR  T L V   P  +    +   
Sbjct: 1886 QRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFT-LTVQVPPTFENPKTETVS 1944

Query: 174  SQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADG 233
                + + L     G P   ++WL       +    S  + G V+   R  L     A  
Sbjct: 1945 QVAGSPLVLTCDVSGVPAPTVTWLKD-----RMPVESSAVHGVVSRGGRLQLSRLQPAQA 1999

Query: 234  VTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGY-DDNWYLGRTDATLSCDVRSNPEP 291
             T TC  E+   E  A     ++V   P +  SG   ++  L   +  L C+    P P
Sbjct: 2000 GTYTCVAENTQAE--ARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPP 2056



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 42/189 (22%), Positives = 75/189 (39%), Gaps = 21/189 (11%)

Query: 111  STGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLR----VIAKP---- 162
            S G +         L +  +  E+ G Y+C+ +     +  G  WL     V+  P    
Sbjct: 1601 SAGDEVSVLQGGRVLQIPLVRAENAGRYSCKAS-----NEVGEDWLHYELLVLTPPVILG 1655

Query: 163  KNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSR 222
              +   ++VT +   +TV+L     G P   ISWL +    +   ++     G V   S 
Sbjct: 1656 DTEELVEEVTVNAS-STVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVST 1714

Query: 223  FTLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLS 282
              +     AD  +  C  E+++     L   TL V+ PP ++    +    +  +  +L 
Sbjct: 1715 AEV-----ADAASYMCVAENQAGSAEKLF--TLRVQVPPRIAGLDLEQVTAILNSSVSLP 1767

Query: 283  CDVRSNPEP 291
            CDV ++P P
Sbjct: 1768 CDVHAHPNP 1776



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 2/87 (2%)

Query: 113  GQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVT 172
            G     +LQ+ +L +H    +D G Y C  A    G  + +  L + + P  Q E Q +T
Sbjct: 3070 GSHLRHQLQNGSLTIHRTERDDAGRYQC-LAENEMGVAKKVVILVLQSAPVFQVEPQDMT 3128

Query: 173  FSQDPTTVALCISKEGRPPARISWLSS 199
              +    VAL     G P   I WL +
Sbjct: 3129 V-RSGDDVALRCQATGEPTPTIEWLQA 3154



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 33/122 (27%), Positives = 50/122 (40%), Gaps = 9/122 (7%)

Query: 95  SPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMT 154
           +PKP        S++   GQ   A L++ +L L  ++  D G+Y C+ AT   GS     
Sbjct: 29  TPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQ-ATNEVGSTSRRA 87

Query: 155 WLRVIAKPKNQAEAQKVTFS-QDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTL 213
            L V   P  + + +K   S     ++ L     G P   I WL       K+ Q+ G  
Sbjct: 88  KLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWL-------KDAQLVGVP 140

Query: 214 AG 215
            G
Sbjct: 141 LG 142



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 28/102 (27%), Positives = 35/102 (34%), Gaps = 5/102 (4%)

Query: 281 LSCDVRSNPEPTGYDWSTTSGTFPTSA----VAQGSQLVIHAVDSLFNTTFVCTVTNAVG 336
           L C+ R  P P    W       PTS        G QL +    S     + C  +NAVG
Sbjct: 331 LLCEARGVPTPN-ITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVG 389

Query: 337 MGRAEQVIFVRETPRASPRDVGPLVWGAVGGTLLVLLLLAGG 378
                  + V   P        P V  AV G  + L  +A G
Sbjct: 390 AAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARG 431


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 63/249 (25%), Positives = 93/249 (37%), Gaps = 22/249 (8%)

Query: 110  QSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKP--KNQAE 167
            Q  G      L   +L L GL   D G YTC  A  P G    +  + V+  P  K  A+
Sbjct: 3260 QDMGPHLRFYLDGGSLVLKGLRASDAGAYTC-VAHNPAGEDARLHTVNVLVPPTIKQGAD 3318

Query: 168  AQKVTFSQDPTTVALCISKEGRPPARISWL-SSLDWE-AKETQVSGTLAGTVTVTSRFTL 225
                  S+    V +     G PP  +SWL   L    ++ T + G  +G     S+  L
Sbjct: 3319 GSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHG--SGHTLRISKVQL 3376

Query: 226  VPSGRADGVTVTCKVEHESFEEPALIP---VTLSVRYPPEVSISGYDDNWYLGRTD-ATL 281
                 AD    TC         PA +     TL V+ PP +    + ++  + R     L
Sbjct: 3377 -----ADAGIFTCVA-----ASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVEL 3426

Query: 282  SCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
             C+ R  P P    W        + ++ QG  L + AV +  + T+ C   +  G  R  
Sbjct: 3427 PCEARGVPLPL-VSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRH 3485

Query: 342  QVIFVRETP 350
              + V E P
Sbjct: 3486 FQLTVMEPP 3494



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 71/276 (25%), Positives = 107/276 (38%), Gaps = 29/276 (10%)

Query: 111  STGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQK 170
            +TG  T+  L    L +   + ED GNY C  A    GS  G T L V   P  +     
Sbjct: 3989 ATGVSTQV-LPGGQLRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIENGLPD 4046

Query: 171  VTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGR 230
            ++ ++       C ++    P       ++ W+     VSG          +FT+ PSG 
Sbjct: 4047 LSTTEGSHAFLPCKARGSPEP-------NITWDKDGQPVSGA-------EGKFTIQPSGE 4092

Query: 231  A--------DGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLS 282
                     D  T TC  E+        + +T+ V  P   ++ G D +  LG     L 
Sbjct: 4093 LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILV-LPVFTTLPG-DRSLRLGDR-LWLR 4149

Query: 283  CDVRSNPEPT-GYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
            C  R +P P  G+  +    T   S    GS L   AV    + T+VC   N VG  +A 
Sbjct: 4150 CAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAV 4209

Query: 342  QVIFVRETPRASPRDVGPLVWGAVGGTLLVLLLLAG 377
              + V+E P         LV   VGG++ +  ++ G
Sbjct: 4210 SFVHVKEAPVLQGEAFSYLV-EPVGGSIQLDCVVRG 4244



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 64/274 (23%), Positives = 104/274 (37%), Gaps = 32/274 (11%)

Query: 93  FPSPKPGSERLSFVSAKQSTGQDTEAELQ-DATLALHGLTVEDEGNYTCEFATFPKGSVR 151
           +P+P      +S+    Q+  +D+   +    TL + G+  ED GNY+C+ AT   G+ +
Sbjct: 634 YPTP-----HISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQ-ATNEVGTDQ 687

Query: 152 GMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSG 211
               L     P   A    V  +     V +C    G PP R+ W            +  
Sbjct: 688 ETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVC-EASGVPPPRVIWYRG--------GLEM 738

Query: 212 TLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDN 271
            LA   + + +  +  +   D  T TC+  +E  +  A   + L+V + P+++    D  
Sbjct: 739 ILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASA--EIQLAVGHAPQLTELPRDVT 796

Query: 272 WYLGRTDATLSCDVRSNPEPTGYDW----------STTSGTFPTSAVAQGSQLVIHAVDS 321
             LGR+ A L+C     P PT   W             +G    S       L   +V  
Sbjct: 797 VELGRS-ALLACRATGRPPPT-VTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAP 854

Query: 322 LFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPR 355
                +VC   N  G  +AE  + V  T  A P+
Sbjct: 855 EDQAPYVCEARNVFGKVQAEARLIV--TGHAPPQ 886



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 51/233 (21%), Positives = 88/233 (37%), Gaps = 18/233 (7%)

Query: 125  LALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCI 184
            L +  + + DEG YTC  AT   G  +    L+V+  P  +         ++ +    C+
Sbjct: 1850 LQIEKVDLRDEGIYTCA-ATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECL 1908

Query: 185  SKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGR-ADGVTVTCKVEHE 243
            +  G PP  +SW            VS  +  TV+V  R   +   + +D  +  C   + 
Sbjct: 1909 AS-GVPPPDVSWFKG------HQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNV 1961

Query: 244  SFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDW------S 297
            +      +   L V  PP +++        L  T   L+C+    P PT   W       
Sbjct: 1962 AGSTE--LRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPT-LMWLKDGNPV 2018

Query: 298  TTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP 350
            + +GT        G  L + +  +  +  + C   +AVG  R + V+ V   P
Sbjct: 2019 SPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPP 2071



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 56/238 (23%), Positives = 89/238 (37%), Gaps = 22/238 (9%)

Query: 124  TLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV--- 180
            TL L    + D G YTCE A    G  + +  L V+  P   A  Q     QD   V   
Sbjct: 2992 TLQLGRARLSDSGMYTCE-ALNAAGRDQKLVQLSVLVPP---AFRQAPRGPQDAVLVRVG 3047

Query: 181  ---ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVT 237
                L    +  P   ++W     ++  +  V       +    R  +  +  +D    +
Sbjct: 3048 DKAVLSCETDALPEPTVTW-----YKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYS 3102

Query: 238  CKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWS 297
            CKV + + E  A+   TL+V+ PP       +    +  +   L+CDV   P PT   W 
Sbjct: 3103 CKVSNVAGE--AVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPT-VTWL 3159

Query: 298  TTSGTFPTSAV----AQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPR 351
                   +SAV    ++G +L +  +      T+ C   N     R + V+ V   PR
Sbjct: 3160 KDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPR 3217



 Score = 36.2 bits (82), Expect = 0.068
 Identities = 52/215 (24%), Positives = 79/215 (36%), Gaps = 19/215 (8%)

Query: 91   PSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSV 150
            P+  +PKP        S++   GQ   A L++ +L L  ++  D G+Y C+ AT   GS 
Sbjct: 1229 PARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQ-ATNEVGST 1287

Query: 151  RGMTWLRVIAKPKNQAEAQKVTFS-QDPTTVALCISKEGRPPARISWL------------ 197
                 L V   P  + + +K   S     ++ L     G P   I WL            
Sbjct: 1288 SRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGW 1347

Query: 198  SSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIPVTLSV 257
            +   W+    QV G        +  F  +  G  D    +C+ E+++    A     L V
Sbjct: 1348 AGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEG--DSGLYSCRAENQA--GTAQRDFHLLV 1403

Query: 258  RYPPEVSISG-YDDNWYLGRTDATLSCDVRSNPEP 291
              PP V  +G   +   L   D  L C     P P
Sbjct: 1404 LTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTP 1438



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 56/239 (23%), Positives = 85/239 (35%), Gaps = 18/239 (7%)

Query: 134  DEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQK--VTFSQDPTTVALCISKEGRPP 191
            D G YTC+ A+   G+    T L V   P  +    +  V  +     VAL     G P 
Sbjct: 1567 DAGVYTCK-ASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPS 1625

Query: 192  ARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALI 251
              +SW       A+  +      G+V       L   G A     +C     + E  A++
Sbjct: 1626 PTLSWHHEGLPVAESNESRLETDGSV-----LRLESPGEASSGLYSCVASSPAGE--AVL 1678

Query: 252  PVTLSVRYPPEVSIS-GYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSA--- 307
              ++ V+ PP++ ++ G      +      L C    +P PT   W          A   
Sbjct: 1679 QYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPT-IQWLQNGRPAEELAGVQ 1737

Query: 308  -VAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRE--TPRASPRDVGPLVWG 363
              +QG+ L I  V+   +  F C  TN  G   AE  + V     P      +G   WG
Sbjct: 1738 VASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWG 1796



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 41/179 (22%), Positives = 65/179 (36%), Gaps = 9/179 (5%)

Query: 114  QDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTF 173
            Q T+A      L +    V D+G Y+C+ +     +VR  T L V   P  +    +   
Sbjct: 3077 QRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFT-LTVQVPPTFENPKTETVS 3135

Query: 174  SQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADG 233
                + + L     G P   ++WL       +    S  + G V+   R  L     A  
Sbjct: 3136 QVAGSPLVLTCDVSGVPAPTVTWLKD-----RMPVESSAVHGVVSRGGRLQLSRLQPAQA 3190

Query: 234  VTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGY-DDNWYLGRTDATLSCDVRSNPEP 291
             T TC  E+   E  A     ++V   P +  SG   ++  L   +  L C+    P P
Sbjct: 3191 GTYTCVAENTQAE--ARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPP 3247



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 42/189 (22%), Positives = 75/189 (39%), Gaps = 21/189 (11%)

Query: 111  STGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLR----VIAKP---- 162
            S G +         L +  +  E+ G Y+C+ +     +  G  WL     V+  P    
Sbjct: 2792 SAGDEVSVLQGGRVLQIPLVRAENAGRYSCKAS-----NEVGEDWLHYELLVLTPPVILG 2846

Query: 163  KNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSR 222
              +   ++VT +   +TV+L     G P   ISWL +    +   ++     G V   S 
Sbjct: 2847 DTEELVEEVTVNAS-STVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVST 2905

Query: 223  FTLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLS 282
              +     AD  +  C  E+++     L   TL V+ PP ++    +    +  +  +L 
Sbjct: 2906 AEV-----ADAASYMCVAENQAGSAEKLF--TLRVQVPPRIAGLDLEQVTAILNSSVSLP 2958

Query: 283  CDVRSNPEP 291
            CDV ++P P
Sbjct: 2959 CDVHAHPNP 2967



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 2/87 (2%)

Query: 113  GQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVT 172
            G     +LQ+ +L +H    +D G Y C  A    G  + +  L + + P  Q E Q +T
Sbjct: 4261 GSHLRHQLQNGSLTIHRTERDDAGRYQC-LAENEMGVAKKVVILVLQSAPVFQVEPQDMT 4319

Query: 173  FSQDPTTVALCISKEGRPPARISWLSS 199
              +    VAL     G P   I WL +
Sbjct: 4320 V-RSGDDVALRCQATGEPTPTIEWLQA 4345



 Score = 32.3 bits (72), Expect = 0.97
 Identities = 63/269 (23%), Positives = 91/269 (33%), Gaps = 30/269 (11%)

Query: 125  LALHGLTVEDEGNYTCEFAT-FPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALC 183
            L    +  ED+  Y CE    F K        +   A P+  + A  V   +       C
Sbjct: 847  LFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPC 906

Query: 184  ISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGV-TVTCKVEH 242
            I   GRP     WL         ++ S    G++ +  R     +GR   V T T   +H
Sbjct: 907  IVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHL-DRALQEHAGRYSCVATNTAGSQH 965

Query: 243  ESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGT 302
               E        L V+ PP +  +        G   A+L C     P PT   W+  +  
Sbjct: 966  RDVE--------LVVQVPPRIHPTATHHITNEG-VPASLPCVASGVPAPT-ITWTKETNA 1015

Query: 303  F----PTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDVG 358
                 P   V++   L+I    +     +VCT TN VG    E  + V          + 
Sbjct: 1016 LTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLA------LS 1069

Query: 359  PLVWGAVGGTLLVLLLLAGGSLAFILLRV 387
              VW   G       LL  GSL    ++V
Sbjct: 1070 KYVWEEYG-------LLPSGSLRLAQVQV 1091



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 28/102 (27%), Positives = 35/102 (34%), Gaps = 5/102 (4%)

Query: 281  LSCDVRSNPEPTGYDWSTTSGTFPTSA----VAQGSQLVIHAVDSLFNTTFVCTVTNAVG 336
            L C+ R  P P    W       PTS        G QL +    S     + C  +NAVG
Sbjct: 1522 LLCEARGVPTPN-ITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVG 1580

Query: 337  MGRAEQVIFVRETPRASPRDVGPLVWGAVGGTLLVLLLLAGG 378
                   + V   P        P V  AV G  + L  +A G
Sbjct: 1581 AAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARG 1622


>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3783

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 63/249 (25%), Positives = 93/249 (37%), Gaps = 22/249 (8%)

Query: 110  QSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKP--KNQAE 167
            Q  G      L   +L L GL   D G YTC  A  P G    +  + V+  P  K  A+
Sbjct: 1978 QDMGPHLRFYLDGGSLVLKGLRASDAGAYTC-VAHNPAGEDARLHTVNVLVPPTIKQGAD 2036

Query: 168  AQKVTFSQDPTTVALCISKEGRPPARISWL-SSLDWE-AKETQVSGTLAGTVTVTSRFTL 225
                  S+    V +     G PP  +SWL   L    ++ T + G  +G     S+  L
Sbjct: 2037 GSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHG--SGHTLRISKVQL 2094

Query: 226  VPSGRADGVTVTCKVEHESFEEPALIP---VTLSVRYPPEVSISGYDDNWYLGRTD-ATL 281
                 AD    TC         PA +     TL V+ PP +    + ++  + R     L
Sbjct: 2095 -----ADAGIFTCVA-----ASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVEL 2144

Query: 282  SCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
             C+ R  P P    W        + ++ QG  L + AV +  + T+ C   +  G  R  
Sbjct: 2145 PCEARGVPLPL-VSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRH 2203

Query: 342  QVIFVRETP 350
              + V E P
Sbjct: 2204 FQLTVMEPP 2212



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 71/276 (25%), Positives = 107/276 (38%), Gaps = 29/276 (10%)

Query: 111  STGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQK 170
            +TG  T+  L    L +   + ED GNY C  A    GS  G T L V   P  +     
Sbjct: 2707 ATGVSTQV-LPGGQLRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIENGLPD 2764

Query: 171  VTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGR 230
            ++ ++       C ++    P       ++ W+     VSG          +FT+ PSG 
Sbjct: 2765 LSTTEGSHAFLPCKARGSPEP-------NITWDKDGQPVSGA-------EGKFTIQPSGE 2810

Query: 231  A--------DGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLS 282
                     D  T TC  E+        + +T+ V  P   ++ G D +  LG     L 
Sbjct: 2811 LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILV-LPVFTTLPG-DRSLRLGDR-LWLR 2867

Query: 283  CDVRSNPEPT-GYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
            C  R +P P  G+  +    T   S    GS L   AV    + T+VC   N VG  +A 
Sbjct: 2868 CAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAV 2927

Query: 342  QVIFVRETPRASPRDVGPLVWGAVGGTLLVLLLLAG 377
              + V+E P         LV   VGG++ +  ++ G
Sbjct: 2928 SFVHVKEAPVLQGEAFSYLV-EPVGGSIQLDCVVRG 2962



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 51/233 (21%), Positives = 88/233 (37%), Gaps = 18/233 (7%)

Query: 125 LALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCI 184
           L +  + + DEG YTC  AT   G  +    L+V+  P  +         ++ +    C+
Sbjct: 568 LQIEKVDLRDEGIYTCA-ATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECL 626

Query: 185 SKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGR-ADGVTVTCKVEHE 243
           +  G PP  +SW            VS  +  TV+V  R   +   + +D  +  C   + 
Sbjct: 627 AS-GVPPPDVSWFKG------HQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNV 679

Query: 244 SFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDW------S 297
           +      +   L V  PP +++        L  T   L+C+    P PT   W       
Sbjct: 680 AGSTE--LRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPT-LMWLKDGNPV 736

Query: 298 TTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP 350
           + +GT        G  L + +  +  +  + C   +AVG  R + V+ V   P
Sbjct: 737 SPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPP 789



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 56/238 (23%), Positives = 89/238 (37%), Gaps = 22/238 (9%)

Query: 124  TLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV--- 180
            TL L    + D G YTCE A    G  + +  L V+  P   A  Q     QD   V   
Sbjct: 1710 TLQLGRARLSDSGMYTCE-ALNAAGRDQKLVQLSVLVPP---AFRQAPRGPQDAVLVRVG 1765

Query: 181  ---ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVT 237
                L    +  P   ++W     ++  +  V       +    R  +  +  +D    +
Sbjct: 1766 DKAVLSCETDALPEPTVTW-----YKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYS 1820

Query: 238  CKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWS 297
            CKV + + E  A+   TL+V+ PP       +    +  +   L+CDV   P PT   W 
Sbjct: 1821 CKVSNVAGE--AVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPT-VTWL 1877

Query: 298  TTSGTFPTSAV----AQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPR 351
                   +SAV    ++G +L +  +      T+ C   N     R + V+ V   PR
Sbjct: 1878 KDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPR 1935



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 56/239 (23%), Positives = 85/239 (35%), Gaps = 18/239 (7%)

Query: 134 DEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQK--VTFSQDPTTVALCISKEGRPP 191
           D G YTC+ A+   G+    T L V   P  +    +  V  +     VAL     G P 
Sbjct: 285 DAGVYTCK-ASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPS 343

Query: 192 ARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALI 251
             +SW       A+  +      G+V       L   G A     +C     + E  A++
Sbjct: 344 PTLSWHHEGLPVAESNESRLETDGSV-----LRLESPGEASSGLYSCVASSPAGE--AVL 396

Query: 252 PVTLSVRYPPEVSIS-GYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSA--- 307
             ++ V+ PP++ ++ G      +      L C    +P PT   W          A   
Sbjct: 397 QYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPT-IQWLQNGRPAEELAGVQ 455

Query: 308 -VAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRE--TPRASPRDVGPLVWG 363
             +QG+ L I  V+   +  F C  TN  G   AE  + V     P      +G   WG
Sbjct: 456 VASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWG 514



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 41/179 (22%), Positives = 65/179 (36%), Gaps = 9/179 (5%)

Query: 114  QDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTF 173
            Q T+A      L +    V D+G Y+C+ +     +VR  T L V   P  +    +   
Sbjct: 1795 QRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFT-LTVQVPPTFENPKTETVS 1853

Query: 174  SQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADG 233
                + + L     G P   ++WL       +    S  + G V+   R  L     A  
Sbjct: 1854 QVAGSPLVLTCDVSGVPAPTVTWLKD-----RMPVESSAVHGVVSRGGRLQLSRLQPAQA 1908

Query: 234  VTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGY-DDNWYLGRTDATLSCDVRSNPEP 291
             T TC  E+   E  A     ++V   P +  SG   ++  L   +  L C+    P P
Sbjct: 1909 GTYTCVAENTQAE--ARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPP 1965



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 42/189 (22%), Positives = 75/189 (39%), Gaps = 21/189 (11%)

Query: 111  STGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLR----VIAKP---- 162
            S G +         L +  +  E+ G Y+C+ +     +  G  WL     V+  P    
Sbjct: 1510 SAGDEVSVLQGGRVLQIPLVRAENAGRYSCKAS-----NEVGEDWLHYELLVLTPPVILG 1564

Query: 163  KNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSR 222
              +   ++VT +   +TV+L     G P   ISWL +    +   ++     G V   S 
Sbjct: 1565 DTEELVEEVTVNAS-STVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVST 1623

Query: 223  FTLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLS 282
              +     AD  +  C  E+++     L   TL V+ PP ++    +    +  +  +L 
Sbjct: 1624 AEV-----ADAASYMCVAENQAGSAEKLF--TLRVQVPPRIAGLDLEQVTAILNSSVSLP 1676

Query: 283  CDVRSNPEP 291
            CDV ++P P
Sbjct: 1677 CDVHAHPNP 1685



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 2/87 (2%)

Query: 113  GQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVT 172
            G     +LQ+ +L +     +D G Y C  A    G  + +  L + + P  Q E Q +T
Sbjct: 2979 GSHLRHQLQNGSLTIRRTERDDAGRYQC-LAENEMGVAKKVVILVLQSAPVFQVEPQDMT 3037

Query: 173  FSQDPTTVALCISKEGRPPARISWLSS 199
              +    VAL     G P   I WL +
Sbjct: 3038 V-RSGDDVALRCQATGEPTPTIEWLQA 3063



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 28/102 (27%), Positives = 35/102 (34%), Gaps = 5/102 (4%)

Query: 281 LSCDVRSNPEPTGYDWSTTSGTFPTSA----VAQGSQLVIHAVDSLFNTTFVCTVTNAVG 336
           L C+ R  P P    W       PTS        G QL +    S     + C  +NAVG
Sbjct: 240 LLCEARGVPTPN-ITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVG 298

Query: 337 MGRAEQVIFVRETPRASPRDVGPLVWGAVGGTLLVLLLLAGG 378
                  + V   P        P V  AV G  + L  +A G
Sbjct: 299 AAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARG 340


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,665,713
Number of Sequences: 37866
Number of extensions: 1254998
Number of successful extensions: 11417
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 103
Number of HSP's successfully gapped in prelim test: 257
Number of HSP's that attempted gapping in prelim test: 10118
Number of HSP's gapped (non-prelim): 1243
length of query: 479
length of database: 18,247,518
effective HSP length: 106
effective length of query: 373
effective length of database: 14,233,722
effective search space: 5309178306
effective search space used: 5309178306
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.