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Search of human proteins with 51226124
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform
1 [Homo sapiens]
(2036 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform 1... 4098 0.0
gi|51230412 GTPase activating Rap/RanGAP domain-like 1 isoform 2... 4093 0.0
gi|118600961 akt substrate AS250 [Homo sapiens] 1148 0.0
gi|116256350 tuberous sclerosis 2 isoform 4 [Homo sapiens] 100 2e-20
gi|116256352 tuberous sclerosis 2 isoform 1 [Homo sapiens] 100 2e-20
gi|167412124 tuberous sclerosis 2 isoform 5 [Homo sapiens] 100 2e-20
gi|207448705 GTPase activating Rap/RanGAP domain-like 3 [Homo sa... 84 1e-15
gi|224809582 RAP1 GTPase activating protein isoform c [Homo sapi... 77 2e-13
gi|224809578 RAP1 GTPase activating protein isoform a [Homo sapi... 77 2e-13
gi|224809573 RAP1 GTPase activating protein isoform b [Homo sapi... 77 2e-13
gi|156086740 GTPase activating Rap/RanGAP domain-like 4 isoform ... 75 5e-13
gi|156086724 GTPase activating Rap/RanGAP domain-like 4 isoform ... 75 5e-13
gi|112421013 signal-induced proliferation-associated 1 like 2 [H... 74 1e-12
gi|7662126 signal-induced proliferation-associated 1 like 1 [Hom... 73 2e-12
gi|71143119 signal-induced proliferation-associated 1 like 3 [Ho... 72 7e-12
gi|206725526 signal-induced proliferation-associated protein 1 [... 67 1e-10
gi|206725523 signal-induced proliferation-associated protein 1 [... 67 1e-10
gi|34787409 hypothetical protein LOC57148 [Homo sapiens] 63 3e-09
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 40 0.018
gi|150456424 RW1 protein [Homo sapiens] 39 0.040
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 39 0.068
gi|161016767 mucin 21 [Homo sapiens] 37 0.26
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 36 0.44
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 35 0.75
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] 35 0.75
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] 35 0.75
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] 35 0.75
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ... 35 0.75
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] 35 0.75
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] 35 0.75
>gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform 1
[Homo sapiens]
Length = 2036
Score = 4098 bits (10629), Expect = 0.0
Identities = 2036/2036 (100%), Positives = 2036/2036 (100%)
Query: 1 MFSKKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIENAESIDLKQFFDQHFSHIYYVFFE 60
MFSKKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIENAESIDLKQFFDQHFSHIYYVFFE
Sbjct: 1 MFSKKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIENAESIDLKQFFDQHFSHIYYVFFE 60
Query: 61 NFVTIEASLKQKGHKSQREELDAILFIFEKILQLLPERIHQRWQFHSIGLILKKLLHTGN 120
NFVTIEASLKQKGHKSQREELDAILFIFEKILQLLPERIHQRWQFHSIGLILKKLLHTGN
Sbjct: 61 NFVTIEASLKQKGHKSQREELDAILFIFEKILQLLPERIHQRWQFHSIGLILKKLLHTGN 120
Query: 121 SLKIRREGVRLFLLWLQALQNNCSKEQLWMFSCLIPGFSAPQSEHGPRTLDNLINPPLNL 180
SLKIRREGVRLFLLWLQALQNNCSKEQLWMFSCLIPGFSAPQSEHGPRTLDNLINPPLNL
Sbjct: 121 SLKIRREGVRLFLLWLQALQNNCSKEQLWMFSCLIPGFSAPQSEHGPRTLDNLINPPLNL 180
Query: 181 QETQVTIEEITPLVPPQSGDKGQEDLTSYFLEALLKYIVIQVKSLEWKNKENQERGFSFL 240
QETQVTIEEITPLVPPQSGDKGQEDLTSYFLEALLKYIVIQVKSLEWKNKENQERGFSFL
Sbjct: 181 QETQVTIEEITPLVPPQSGDKGQEDLTSYFLEALLKYIVIQVKSLEWKNKENQERGFSFL 240
Query: 241 FSHFKKYYLPYIFPNICKENSLYHPILDIPQMRPKPHYVVIKKDAETNEAIYCTKEPFIK 300
FSHFKKYYLPYIFPNICKENSLYHPILDIPQMRPKPHYVVIKKDAETNEAIYCTKEPFIK
Sbjct: 241 FSHFKKYYLPYIFPNICKENSLYHPILDIPQMRPKPHYVVIKKDAETNEAIYCTKEPFIK 300
Query: 301 ARVIVIRWLVSFWLEPKPHTGPHIPGMEGEVLPKNIQRAAASLVSREESKNDNADKTDRT 360
ARVIVIRWLVSFWLEPKPHTGPHIPGMEGEVLPKNIQRAAASLVSREESKNDNADKTDRT
Sbjct: 301 ARVIVIRWLVSFWLEPKPHTGPHIPGMEGEVLPKNIQRAAASLVSREESKNDNADKTDRT 360
Query: 361 TEPEQSHSNTSTLTEREPSSSSLCSIDEEHLTDIEIVRRVFSSKRSNVNFVTEIFRQAFL 420
TEPEQSHSNTSTLTEREPSSSSLCSIDEEHLTDIEIVRRVFSSKRSNVNFVTEIFRQAFL
Sbjct: 361 TEPEQSHSNTSTLTEREPSSSSLCSIDEEHLTDIEIVRRVFSSKRSNVNFVTEIFRQAFL 420
Query: 421 LPICEAAAMRKVVKVYQEWIQQEEKPLFMQEPEEIVITSSDLPCIENVTDHDISMEEGEK 480
LPICEAAAMRKVVKVYQEWIQQEEKPLFMQEPEEIVITSSDLPCIENVTDHDISMEEGEK
Sbjct: 421 LPICEAAAMRKVVKVYQEWIQQEEKPLFMQEPEEIVITSSDLPCIENVTDHDISMEEGEK 480
Query: 481 REEENGTNTADHVRNSSWAKNGSYQGALHNASEEATEQNIRAGTQAVLQVFIINSSNIFL 540
REEENGTNTADHVRNSSWAKNGSYQGALHNASEEATEQNIRAGTQAVLQVFIINSSNIFL
Sbjct: 481 REEENGTNTADHVRNSSWAKNGSYQGALHNASEEATEQNIRAGTQAVLQVFIINSSNIFL 540
Query: 541 LEPANEIKNLLDEHTDMCKRILNIYRYMVVQVSMDKKTWEQMLLVLLRVTESVLKMPSQA 600
LEPANEIKNLLDEHTDMCKRILNIYRYMVVQVSMDKKTWEQMLLVLLRVTESVLKMPSQA
Sbjct: 541 LEPANEIKNLLDEHTDMCKRILNIYRYMVVQVSMDKKTWEQMLLVLLRVTESVLKMPSQA 600
Query: 601 FLQFQGKKNMTLAGRLAGPLFQTLIVAWIKANLNVYISRELWDDLLSVLSSLTYWEELAT 660
FLQFQGKKNMTLAGRLAGPLFQTLIVAWIKANLNVYISRELWDDLLSVLSSLTYWEELAT
Sbjct: 601 FLQFQGKKNMTLAGRLAGPLFQTLIVAWIKANLNVYISRELWDDLLSVLSSLTYWEELAT 660
Query: 661 EWSLTMETLTKVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGVGHEFQKVSVDKSFSRGW 720
EWSLTMETLTKVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGVGHEFQKVSVDKSFSRGW
Sbjct: 661 EWSLTMETLTKVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGVGHEFQKVSVDKSFSRGW 720
Query: 721 SRDQPGQAPMRQRSATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVRHFSQSEETGN 780
SRDQPGQAPMRQRSATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVRHFSQSEETGN
Sbjct: 721 SRDQPGQAPMRQRSATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVRHFSQSEETGN 780
Query: 781 EVFGALNEEQPLPRSSSTSDILEPFTVERAKVNKEDMSQKLPPLNSDIGGSSANVPDLMD 840
EVFGALNEEQPLPRSSSTSDILEPFTVERAKVNKEDMSQKLPPLNSDIGGSSANVPDLMD
Sbjct: 781 EVFGALNEEQPLPRSSSTSDILEPFTVERAKVNKEDMSQKLPPLNSDIGGSSANVPDLMD 840
Query: 841 EFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAG 900
EFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAG
Sbjct: 841 EFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAG 900
Query: 901 SSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQSAEEQEVASLT 960
SSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQSAEEQEVASLT
Sbjct: 901 SSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQSAEEQEVASLT 960
Query: 961 TLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNIDHMEQKDLQL 1020
TLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNIDHMEQKDLQL
Sbjct: 961 TLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNIDHMEQKDLQL 1020
Query: 1021 DEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLTGWHADVATVMWRRMLGILGDVNSIMD 1080
DEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLTGWHADVATVMWRRMLGILGDVNSIMD
Sbjct: 1021 DEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLTGWHADVATVMWRRMLGILGDVNSIMD 1080
Query: 1081 PEIHAQVFDYLCELWQNLAKIRDNLGISTDNLTSPSPPVLIPPLRILTPWLFKATMLTDK 1140
PEIHAQVFDYLCELWQNLAKIRDNLGISTDNLTSPSPPVLIPPLRILTPWLFKATMLTDK
Sbjct: 1081 PEIHAQVFDYLCELWQNLAKIRDNLGISTDNLTSPSPPVLIPPLRILTPWLFKATMLTDK 1140
Query: 1141 YKQGKLHAYKLICNTMKRRQDVSPNRDFLTHFYNIMHCGLLHIDQDIVNTIIKHCSPQFF 1200
YKQGKLHAYKLICNTMKRRQDVSPNRDFLTHFYNIMHCGLLHIDQDIVNTIIKHCSPQFF
Sbjct: 1141 YKQGKLHAYKLICNTMKRRQDVSPNRDFLTHFYNIMHCGLLHIDQDIVNTIIKHCSPQFF 1200
Query: 1201 SLGLPGATMLIMDFIVAAGRVASSAFLNAPRVEAQVLLGSLVCFPNLYCELPSLHPNIPD 1260
SLGLPGATMLIMDFIVAAGRVASSAFLNAPRVEAQVLLGSLVCFPNLYCELPSLHPNIPD
Sbjct: 1201 SLGLPGATMLIMDFIVAAGRVASSAFLNAPRVEAQVLLGSLVCFPNLYCELPSLHPNIPD 1260
Query: 1261 VAVSQFTDVKELIIKTVLSSARDEPSGPARCVALCSLGIWICEELVHESHHPQIKEALNV 1320
VAVSQFTDVKELIIKTVLSSARDEPSGPARCVALCSLGIWICEELVHESHHPQIKEALNV
Sbjct: 1261 VAVSQFTDVKELIIKTVLSSARDEPSGPARCVALCSLGIWICEELVHESHHPQIKEALNV 1320
Query: 1321 ICVSLKFTNKTVAHVACNMLHMLVHYVPRLQIYQPDSPLKIIQILIATITHLLPSTEASS 1380
ICVSLKFTNKTVAHVACNMLHMLVHYVPRLQIYQPDSPLKIIQILIATITHLLPSTEASS
Sbjct: 1321 ICVSLKFTNKTVAHVACNMLHMLVHYVPRLQIYQPDSPLKIIQILIATITHLLPSTEASS 1380
Query: 1381 YEMDKRLVVSLLLCLLDWIMALPLKTLLQPFHATGAESDKTEKSVLNCIYKVLHGCVYGA 1440
YEMDKRLVVSLLLCLLDWIMALPLKTLLQPFHATGAESDKTEKSVLNCIYKVLHGCVYGA
Sbjct: 1381 YEMDKRLVVSLLLCLLDWIMALPLKTLLQPFHATGAESDKTEKSVLNCIYKVLHGCVYGA 1440
Query: 1441 QCFSNPRYFPMSLSDLASVDYDPFMHLESLKEPEPLHSPDSERSSKLQPVTEVKTQMQHG 1500
QCFSNPRYFPMSLSDLASVDYDPFMHLESLKEPEPLHSPDSERSSKLQPVTEVKTQMQHG
Sbjct: 1441 QCFSNPRYFPMSLSDLASVDYDPFMHLESLKEPEPLHSPDSERSSKLQPVTEVKTQMQHG 1500
Query: 1501 LISIAARTVITHLVNHLGHYPMSGGPAMLTSQVCENHDNHYSESTELSPELFESPNIQFF 1560
LISIAARTVITHLVNHLGHYPMSGGPAMLTSQVCENHDNHYSESTELSPELFESPNIQFF
Sbjct: 1501 LISIAARTVITHLVNHLGHYPMSGGPAMLTSQVCENHDNHYSESTELSPELFESPNIQFF 1560
Query: 1561 VLNNTTLVSCIQIRSEENMPGGGLSAGLASANSNVRIIVRDLSGKYSWDSAILYGPPPVS 1620
VLNNTTLVSCIQIRSEENMPGGGLSAGLASANSNVRIIVRDLSGKYSWDSAILYGPPPVS
Sbjct: 1561 VLNNTTLVSCIQIRSEENMPGGGLSAGLASANSNVRIIVRDLSGKYSWDSAILYGPPPVS 1620
Query: 1621 GLSEPTSFMLSLSHQEKPEEPPTSNECLEDITVKDGLSLQFKRFRETVPTWDTIRDEEDV 1680
GLSEPTSFMLSLSHQEKPEEPPTSNECLEDITVKDGLSLQFKRFRETVPTWDTIRDEEDV
Sbjct: 1621 GLSEPTSFMLSLSHQEKPEEPPTSNECLEDITVKDGLSLQFKRFRETVPTWDTIRDEEDV 1680
Query: 1681 LDELLQYLGVTSPECLQRTGISLNIPAPQPVCISEKQENDVINAILKQHTEEKEFVEKHF 1740
LDELLQYLGVTSPECLQRTGISLNIPAPQPVCISEKQENDVINAILKQHTEEKEFVEKHF
Sbjct: 1681 LDELLQYLGVTSPECLQRTGISLNIPAPQPVCISEKQENDVINAILKQHTEEKEFVEKHF 1740
Query: 1741 NDLNMKAVEQDEPIPQKPQSAFYYCRLLLSILGMNSWDKRRSFHLLKKNEKLLRELRNLD 1800
NDLNMKAVEQDEPIPQKPQSAFYYCRLLLSILGMNSWDKRRSFHLLKKNEKLLRELRNLD
Sbjct: 1741 NDLNMKAVEQDEPIPQKPQSAFYYCRLLLSILGMNSWDKRRSFHLLKKNEKLLRELRNLD 1800
Query: 1801 SRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQK 1860
SRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQK
Sbjct: 1801 SRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQK 1860
Query: 1861 NKSTGLTTPYFATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHTRDYRRG 1920
NKSTGLTTPYFATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHTRDYRRG
Sbjct: 1861 NKSTGLTTPYFATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHTRDYRRG 1920
Query: 1921 IIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLFDGAIVNGKVLPIMVRATAINAS 1980
IIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLFDGAIVNGKVLPIMVRATAINAS
Sbjct: 1921 IIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLFDGAIVNGKVLPIMVRATAINAS 1980
Query: 1981 RALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFEDFAAQVFSPAPYHHLPSDADH 2036
RALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFEDFAAQVFSPAPYHHLPSDADH
Sbjct: 1981 RALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFEDFAAQVFSPAPYHHLPSDADH 2036
>gi|51230412 GTPase activating Rap/RanGAP domain-like 1 isoform 2
[Homo sapiens]
Length = 2083
Score = 4093 bits (10615), Expect = 0.0
Identities = 2034/2034 (100%), Positives = 2034/2034 (100%)
Query: 1 MFSKKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIENAESIDLKQFFDQHFSHIYYVFFE 60
MFSKKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIENAESIDLKQFFDQHFSHIYYVFFE
Sbjct: 1 MFSKKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIENAESIDLKQFFDQHFSHIYYVFFE 60
Query: 61 NFVTIEASLKQKGHKSQREELDAILFIFEKILQLLPERIHQRWQFHSIGLILKKLLHTGN 120
NFVTIEASLKQKGHKSQREELDAILFIFEKILQLLPERIHQRWQFHSIGLILKKLLHTGN
Sbjct: 61 NFVTIEASLKQKGHKSQREELDAILFIFEKILQLLPERIHQRWQFHSIGLILKKLLHTGN 120
Query: 121 SLKIRREGVRLFLLWLQALQNNCSKEQLWMFSCLIPGFSAPQSEHGPRTLDNLINPPLNL 180
SLKIRREGVRLFLLWLQALQNNCSKEQLWMFSCLIPGFSAPQSEHGPRTLDNLINPPLNL
Sbjct: 121 SLKIRREGVRLFLLWLQALQNNCSKEQLWMFSCLIPGFSAPQSEHGPRTLDNLINPPLNL 180
Query: 181 QETQVTIEEITPLVPPQSGDKGQEDLTSYFLEALLKYIVIQVKSLEWKNKENQERGFSFL 240
QETQVTIEEITPLVPPQSGDKGQEDLTSYFLEALLKYIVIQVKSLEWKNKENQERGFSFL
Sbjct: 181 QETQVTIEEITPLVPPQSGDKGQEDLTSYFLEALLKYIVIQVKSLEWKNKENQERGFSFL 240
Query: 241 FSHFKKYYLPYIFPNICKENSLYHPILDIPQMRPKPHYVVIKKDAETNEAIYCTKEPFIK 300
FSHFKKYYLPYIFPNICKENSLYHPILDIPQMRPKPHYVVIKKDAETNEAIYCTKEPFIK
Sbjct: 241 FSHFKKYYLPYIFPNICKENSLYHPILDIPQMRPKPHYVVIKKDAETNEAIYCTKEPFIK 300
Query: 301 ARVIVIRWLVSFWLEPKPHTGPHIPGMEGEVLPKNIQRAAASLVSREESKNDNADKTDRT 360
ARVIVIRWLVSFWLEPKPHTGPHIPGMEGEVLPKNIQRAAASLVSREESKNDNADKTDRT
Sbjct: 301 ARVIVIRWLVSFWLEPKPHTGPHIPGMEGEVLPKNIQRAAASLVSREESKNDNADKTDRT 360
Query: 361 TEPEQSHSNTSTLTEREPSSSSLCSIDEEHLTDIEIVRRVFSSKRSNVNFVTEIFRQAFL 420
TEPEQSHSNTSTLTEREPSSSSLCSIDEEHLTDIEIVRRVFSSKRSNVNFVTEIFRQAFL
Sbjct: 361 TEPEQSHSNTSTLTEREPSSSSLCSIDEEHLTDIEIVRRVFSSKRSNVNFVTEIFRQAFL 420
Query: 421 LPICEAAAMRKVVKVYQEWIQQEEKPLFMQEPEEIVITSSDLPCIENVTDHDISMEEGEK 480
LPICEAAAMRKVVKVYQEWIQQEEKPLFMQEPEEIVITSSDLPCIENVTDHDISMEEGEK
Sbjct: 421 LPICEAAAMRKVVKVYQEWIQQEEKPLFMQEPEEIVITSSDLPCIENVTDHDISMEEGEK 480
Query: 481 REEENGTNTADHVRNSSWAKNGSYQGALHNASEEATEQNIRAGTQAVLQVFIINSSNIFL 540
REEENGTNTADHVRNSSWAKNGSYQGALHNASEEATEQNIRAGTQAVLQVFIINSSNIFL
Sbjct: 481 REEENGTNTADHVRNSSWAKNGSYQGALHNASEEATEQNIRAGTQAVLQVFIINSSNIFL 540
Query: 541 LEPANEIKNLLDEHTDMCKRILNIYRYMVVQVSMDKKTWEQMLLVLLRVTESVLKMPSQA 600
LEPANEIKNLLDEHTDMCKRILNIYRYMVVQVSMDKKTWEQMLLVLLRVTESVLKMPSQA
Sbjct: 541 LEPANEIKNLLDEHTDMCKRILNIYRYMVVQVSMDKKTWEQMLLVLLRVTESVLKMPSQA 600
Query: 601 FLQFQGKKNMTLAGRLAGPLFQTLIVAWIKANLNVYISRELWDDLLSVLSSLTYWEELAT 660
FLQFQGKKNMTLAGRLAGPLFQTLIVAWIKANLNVYISRELWDDLLSVLSSLTYWEELAT
Sbjct: 601 FLQFQGKKNMTLAGRLAGPLFQTLIVAWIKANLNVYISRELWDDLLSVLSSLTYWEELAT 660
Query: 661 EWSLTMETLTKVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGVGHEFQKVSVDKSFSRGW 720
EWSLTMETLTKVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGVGHEFQKVSVDKSFSRGW
Sbjct: 661 EWSLTMETLTKVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGVGHEFQKVSVDKSFSRGW 720
Query: 721 SRDQPGQAPMRQRSATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVRHFSQSEETGN 780
SRDQPGQAPMRQRSATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVRHFSQSEETGN
Sbjct: 721 SRDQPGQAPMRQRSATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVRHFSQSEETGN 780
Query: 781 EVFGALNEEQPLPRSSSTSDILEPFTVERAKVNKEDMSQKLPPLNSDIGGSSANVPDLMD 840
EVFGALNEEQPLPRSSSTSDILEPFTVERAKVNKEDMSQKLPPLNSDIGGSSANVPDLMD
Sbjct: 781 EVFGALNEEQPLPRSSSTSDILEPFTVERAKVNKEDMSQKLPPLNSDIGGSSANVPDLMD 840
Query: 841 EFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAG 900
EFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAG
Sbjct: 841 EFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAG 900
Query: 901 SSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQSAEEQEVASLT 960
SSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQSAEEQEVASLT
Sbjct: 901 SSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQSAEEQEVASLT 960
Query: 961 TLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNIDHMEQKDLQL 1020
TLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNIDHMEQKDLQL
Sbjct: 961 TLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNIDHMEQKDLQL 1020
Query: 1021 DEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLTGWHADVATVMWRRMLGILGDVNSIMD 1080
DEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLTGWHADVATVMWRRMLGILGDVNSIMD
Sbjct: 1021 DEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLTGWHADVATVMWRRMLGILGDVNSIMD 1080
Query: 1081 PEIHAQVFDYLCELWQNLAKIRDNLGISTDNLTSPSPPVLIPPLRILTPWLFKATMLTDK 1140
PEIHAQVFDYLCELWQNLAKIRDNLGISTDNLTSPSPPVLIPPLRILTPWLFKATMLTDK
Sbjct: 1081 PEIHAQVFDYLCELWQNLAKIRDNLGISTDNLTSPSPPVLIPPLRILTPWLFKATMLTDK 1140
Query: 1141 YKQGKLHAYKLICNTMKRRQDVSPNRDFLTHFYNIMHCGLLHIDQDIVNTIIKHCSPQFF 1200
YKQGKLHAYKLICNTMKRRQDVSPNRDFLTHFYNIMHCGLLHIDQDIVNTIIKHCSPQFF
Sbjct: 1141 YKQGKLHAYKLICNTMKRRQDVSPNRDFLTHFYNIMHCGLLHIDQDIVNTIIKHCSPQFF 1200
Query: 1201 SLGLPGATMLIMDFIVAAGRVASSAFLNAPRVEAQVLLGSLVCFPNLYCELPSLHPNIPD 1260
SLGLPGATMLIMDFIVAAGRVASSAFLNAPRVEAQVLLGSLVCFPNLYCELPSLHPNIPD
Sbjct: 1201 SLGLPGATMLIMDFIVAAGRVASSAFLNAPRVEAQVLLGSLVCFPNLYCELPSLHPNIPD 1260
Query: 1261 VAVSQFTDVKELIIKTVLSSARDEPSGPARCVALCSLGIWICEELVHESHHPQIKEALNV 1320
VAVSQFTDVKELIIKTVLSSARDEPSGPARCVALCSLGIWICEELVHESHHPQIKEALNV
Sbjct: 1261 VAVSQFTDVKELIIKTVLSSARDEPSGPARCVALCSLGIWICEELVHESHHPQIKEALNV 1320
Query: 1321 ICVSLKFTNKTVAHVACNMLHMLVHYVPRLQIYQPDSPLKIIQILIATITHLLPSTEASS 1380
ICVSLKFTNKTVAHVACNMLHMLVHYVPRLQIYQPDSPLKIIQILIATITHLLPSTEASS
Sbjct: 1321 ICVSLKFTNKTVAHVACNMLHMLVHYVPRLQIYQPDSPLKIIQILIATITHLLPSTEASS 1380
Query: 1381 YEMDKRLVVSLLLCLLDWIMALPLKTLLQPFHATGAESDKTEKSVLNCIYKVLHGCVYGA 1440
YEMDKRLVVSLLLCLLDWIMALPLKTLLQPFHATGAESDKTEKSVLNCIYKVLHGCVYGA
Sbjct: 1381 YEMDKRLVVSLLLCLLDWIMALPLKTLLQPFHATGAESDKTEKSVLNCIYKVLHGCVYGA 1440
Query: 1441 QCFSNPRYFPMSLSDLASVDYDPFMHLESLKEPEPLHSPDSERSSKLQPVTEVKTQMQHG 1500
QCFSNPRYFPMSLSDLASVDYDPFMHLESLKEPEPLHSPDSERSSKLQPVTEVKTQMQHG
Sbjct: 1441 QCFSNPRYFPMSLSDLASVDYDPFMHLESLKEPEPLHSPDSERSSKLQPVTEVKTQMQHG 1500
Query: 1501 LISIAARTVITHLVNHLGHYPMSGGPAMLTSQVCENHDNHYSESTELSPELFESPNIQFF 1560
LISIAARTVITHLVNHLGHYPMSGGPAMLTSQVCENHDNHYSESTELSPELFESPNIQFF
Sbjct: 1501 LISIAARTVITHLVNHLGHYPMSGGPAMLTSQVCENHDNHYSESTELSPELFESPNIQFF 1560
Query: 1561 VLNNTTLVSCIQIRSEENMPGGGLSAGLASANSNVRIIVRDLSGKYSWDSAILYGPPPVS 1620
VLNNTTLVSCIQIRSEENMPGGGLSAGLASANSNVRIIVRDLSGKYSWDSAILYGPPPVS
Sbjct: 1561 VLNNTTLVSCIQIRSEENMPGGGLSAGLASANSNVRIIVRDLSGKYSWDSAILYGPPPVS 1620
Query: 1621 GLSEPTSFMLSLSHQEKPEEPPTSNECLEDITVKDGLSLQFKRFRETVPTWDTIRDEEDV 1680
GLSEPTSFMLSLSHQEKPEEPPTSNECLEDITVKDGLSLQFKRFRETVPTWDTIRDEEDV
Sbjct: 1621 GLSEPTSFMLSLSHQEKPEEPPTSNECLEDITVKDGLSLQFKRFRETVPTWDTIRDEEDV 1680
Query: 1681 LDELLQYLGVTSPECLQRTGISLNIPAPQPVCISEKQENDVINAILKQHTEEKEFVEKHF 1740
LDELLQYLGVTSPECLQRTGISLNIPAPQPVCISEKQENDVINAILKQHTEEKEFVEKHF
Sbjct: 1681 LDELLQYLGVTSPECLQRTGISLNIPAPQPVCISEKQENDVINAILKQHTEEKEFVEKHF 1740
Query: 1741 NDLNMKAVEQDEPIPQKPQSAFYYCRLLLSILGMNSWDKRRSFHLLKKNEKLLRELRNLD 1800
NDLNMKAVEQDEPIPQKPQSAFYYCRLLLSILGMNSWDKRRSFHLLKKNEKLLRELRNLD
Sbjct: 1741 NDLNMKAVEQDEPIPQKPQSAFYYCRLLLSILGMNSWDKRRSFHLLKKNEKLLRELRNLD 1800
Query: 1801 SRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQK 1860
SRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQK
Sbjct: 1801 SRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQK 1860
Query: 1861 NKSTGLTTPYFATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHTRDYRRG 1920
NKSTGLTTPYFATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHTRDYRRG
Sbjct: 1861 NKSTGLTTPYFATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHTRDYRRG 1920
Query: 1921 IIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLFDGAIVNGKVLPIMVRATAINAS 1980
IIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLFDGAIVNGKVLPIMVRATAINAS
Sbjct: 1921 IIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLFDGAIVNGKVLPIMVRATAINAS 1980
Query: 1981 RALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFEDFAAQVFSPAPYHHLPSDA 2034
RALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFEDFAAQVFSPAPYHHLPSDA
Sbjct: 1981 RALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFEDFAAQVFSPAPYHHLPSDA 2034
>gi|118600961 akt substrate AS250 [Homo sapiens]
Length = 1873
Score = 1148 bits (2970), Expect = 0.0
Identities = 589/1025 (57%), Positives = 737/1025 (71%), Gaps = 46/1025 (4%)
Query: 1017 DLQLDEKLHHSVLQTPDDLEISEFPSEC----CSVMAGGTLTGWHADVATVMWRRMLGIL 1072
D+ D H + +P D SEC CS++AGG+LTGWH D A V+WRR+LGIL
Sbjct: 880 DVVADADARHWLQLSPTDASNLTDSSECLTDDCSIIAGGSLTGWHPDSAAVLWRRVLGIL 939
Query: 1073 GDVNSIMDPEIHAQVFDYLCELWQNLAKIRDNLGISTDNLTSPSPPVLIPPLRILTPWLF 1132
GDVN+I P+IHA+VF YL ELW LAKIRDNL IS DN +SPSPPVLIPPLR+ WLF
Sbjct: 940 GDVNNIQSPKIHARVFCYLYELWYKLAKIRDNLAISLDNQSSPSPPVLIPPLRMFASWLF 999
Query: 1133 KATMLTDKYKQGKLHAYKLICNTMKRRQDVSPNRDFLTHFYNIMHCGLLHIDQDIVNTII 1192
KA L ++YK+GKL AY+LIC M RRQDV PN DFL HFY +MH GL DQDI+NTII
Sbjct: 1000 KAATLPNEYKEGKLQAYRLICAMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDILNTII 1059
Query: 1193 KHCSPQFFSLGLPGATMLIMDFIVAAGRVASSAFLNAPRVEAQVLLGSLVCFPNLYCELP 1252
+HC P+FFSLG PG +ML+ DFI AA RV S+ L APR EA +LGSLVCFPN Y E+P
Sbjct: 1060 RHCPPRFFSLGFPGFSMLVGDFITAAARVLSTDILTAPRSEAVTVLGSLVCFPNTYQEIP 1119
Query: 1253 SLHPNIPDV--AVSQFTDVKELIIKTVLSSARDEPSGPARCVALCSLGIWICEELVHESH 1310
L ++P+V A++ DVK +I +L +A +EP+ ARC+A+CSLG+WICEEL +
Sbjct: 1120 LLQ-SVPEVNEAITGTEDVKHYLINILLKNATEEPNEYARCIAVCSLGVWICEELAQCTS 1178
Query: 1311 HPQIKEALNVICVSLKFTNKTVAHVACNMLHMLVHYVPRLQIYQPDSPLKIIQILIATIT 1370
HPQ+KEA+NVI V+LKF NK VA VAC++L +LV Y +LQ+++ P K+ +IL+AT+
Sbjct: 1179 HPQVKEAINVIGVTLKFPNKIVAQVACDVLQLLVSYWEKLQMFETSLPRKMAEILVATVA 1238
Query: 1371 HLLPSTEASSYEMDKRLVVSLLLCLLDWIMALPLKTLLQPFHATGAESDKTEKS-VLNCI 1429
LLPS E SS E DK+ +VSLLLCLLDW MALP+ LL P E + ++ +L+ I
Sbjct: 1239 FLLPSAEYSSVETDKKFIVSLLLCLLDWCMALPVSVLLHPVSTAVLEEQHSARAPLLDYI 1298
Query: 1430 YKVLHGCVYGAQCFSNPRYFPMSLSDLASVDYDPFMHLESLKEPEPLHSPDSERSSKLQP 1489
Y+VLH CV G+ ++ ++ ++L+DL+S DYDPF+ L ++K EP+ S L
Sbjct: 1299 YRVLHCCVCGSSTYTQQSHYILTLADLSSTDYDPFLPLANVKSSEPVQYHSSAELGNLLT 1358
Query: 1490 VTEVKTQMQHGLISIAARTVITHLVNHLGHYPMSGGPAMLTSQVCENHDNHYSESTELSP 1549
V E K + LI + AR V+ HLVNHLGHYP+SGGPA+L S V ENHDN + E +ELS
Sbjct: 1359 VEEEKKRRSLELIPLTARMVMAHLVNHLGHYPLSGGPAILHSLVSENHDNAHVEGSELSF 1418
Query: 1550 ELFESPNIQFFVLNNTTLVSCIQIRSEENMPGGGLSAGLASANSNVRIIVRDLSGKYSWD 1609
E+F SPN+Q FV N++TL+S +Q +E P GG G + S+VR+IVRD+SGKYSWD
Sbjct: 1419 EVFRSPNLQLFVFNDSTLISYLQTPTEG--PVGGSPVG---SLSDVRVIVRDISGKYSWD 1473
Query: 1610 SAILYGPPPVSGLSEPT----SFMLSLSHQEKPEEPPTSNECLEDITVKDGLSLQFKRFR 1665
+LYG P+ G P SF++S H++ S++
Sbjct: 1474 GKVLYG--PLEGCLAPNGRNPSFLISSWHRDTFGPQKDSSQ------------------- 1512
Query: 1666 ETVPTWDTIRDEEDVLDELLQYLGVTSPECLQRTGISLNIPAPQPVCISEKQENDVINAI 1725
+ + +DVLD+LL+ +G TSPECL + ++LN P+ P ++ QE ++I I
Sbjct: 1513 --------VEEGDDVLDKLLENIGHTSPECLLPSQLNLNEPSLTPCGMNYDQEKEIIEVI 1564
Query: 1726 LKQHTEEKEFVEKHFNDLNMKAVEQDEPIPQKPQSAFYYCRLLLSILGMNSWDKRRSFHL 1785
L+Q+ +E E+++ H D MK Q +P P +P+ FY+CRLLL LGMNSWD+R++FHL
Sbjct: 1565 LRQNAQEDEYIQSHNFDSAMKVTSQGQPSPVEPRGPFYFCRLLLDDLGMNSWDRRKNFHL 1624
Query: 1786 LKKNEKLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWE 1845
LKKN KLLREL+NLDSRQCRETHKIAVFY+AEGQEDK SIL+N GSQAYEDFVAGLGWE
Sbjct: 1625 LKKNSKLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILSNERGSQAYEDFVAGLGWE 1684
Query: 1846 VNLTNHCGFMGGLQKNKSTGLTTPYFATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDE 1905
V+L+ HCGFMGGLQ+N STG T PY+ATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDE
Sbjct: 1685 VDLSTHCGFMGGLQRNGSTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDE 1744
Query: 1906 VHIVWSEHTRDYRRGIIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLFDGAIVNG 1965
VHIVWSEH+RDYRRGIIPT FGDV I+IYPMKNHMF I I KKPEVPFFGPLFDGAIV+G
Sbjct: 1745 VHIVWSEHSRDYRRGIIPTAFGDVSIIIYPMKNHMFFIAITKKPEVPFFGPLFDGAIVSG 1804
Query: 1966 KVLPIMVRATAINASRALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFEDFAAQVFSPA 2025
K+LP +V AT INASRA+K LIPLYQ+FYEERA YL+ I+Q+H E TFEDFAAQVFSP+
Sbjct: 1805 KLLPSLVCATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQVFSPS 1864
Query: 2026 PYHHL 2030
P + L
Sbjct: 1865 PSYSL 1869
Score = 799 bits (2064), Expect = 0.0
Identities = 439/889 (49%), Positives = 586/889 (65%), Gaps = 64/889 (7%)
Query: 1 MFSKKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIENAESIDLKQFFDQHFSHIYYVFFE 60
MFS++ HGDVKKSTQKVLD KKD LTRLKHLR +++N ++ DLKQFF+ ++S IY++F+E
Sbjct: 1 MFSRRSHGDVKKSTQKVLDPKKDVLTRLKHLRALLDNVDANDLKQFFETNYSQIYFIFYE 60
Query: 61 NFVTIEASLKQKGH-KSQREELDAILFIFEKILQLLPERIHQRWQFHSIGLILKKLLHTG 119
NF+ +E SLK KG+ KSQREELD+ILF+FEKILQ LPERI RW + SIG LKKLLHTG
Sbjct: 61 NFIALENSLKLKGNNKSQREELDSILFLFEKILQFLPERIFFRWHYQSIGSTLKKLLHTG 120
Query: 120 NSLKIRREGVRLFLLWLQALQNNCSKEQLWMFSCLIPGFSAPQSEHGPRTLDNLINPPLN 179
NS+KIR EG+RLFLLWLQALQ NC++EQ+ +F+CL+PGF A S GP TL+ LINP +
Sbjct: 121 NSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFACLVPGFPAVMSSRGPCTLETLINPSPS 180
Query: 180 LQETQVTIEEITPLVPPQSGDKGQEDLTSYFLEALLKYIVIQVKSLEWKNKENQERGFSF 239
+ + ++ EEITPL+P SG+K ED T +FL+ LLKY+VIQ SLEWKNKENQ+ GF F
Sbjct: 181 VADVKIYPEEITPLLPAISGEKIAEDQTCFFLQILLKYMVIQAASLEWKNKENQDTGFKF 240
Query: 240 LFSHFKKYYLPYIFPNICKENSLYHPILDIPQMRPKPHYVVIKKDAETNEAIYCTKEPFI 299
LF+ F+KYYLP++FP+ K ++Y P+LDIP +RPKP Y+ +D NE IY TK P++
Sbjct: 241 LFTLFRKYYLPHLFPSFTKLTNIYKPVLDIPHLRPKPVYITTTRD---NENIYSTKIPYM 297
Query: 300 KARVIVIRWLVSFWLEPKPHTGPHIPGMEGEVLPKNIQRAAASLVSREESKNDNADKTDR 359
ARV+ I+W+V+F+LE K T +VLPK IQ V + D
Sbjct: 298 AARVVFIKWIVTFFLEKKYLTATQNTKNGVDVLPKIIQTVGGGAVQERAPELDGGG---- 353
Query: 360 TTEPEQSHSNTSTLTEREPSSSSLCSIDEEHLTDIEIVRRVFSSKRSNVNFVTEIFRQAF 419
TE ++SHSN+STL++R S+SSLCSI+EEH E+V+R+ S R VNFV E+F QAF
Sbjct: 354 PTEQDKSHSNSSTLSDRRLSNSSLCSIEEEHRMVYEMVQRILLSTRGYVNFVNEVFHQAF 413
Query: 420 LLPICEAAAMRKVVKVYQEWIQQEEKPLFMQEPEEIVITSSDLPCIENVTDHDISMEEGE 479
LLP CE A RKVV+VY++WI Q +KP+FM+EP+ D++ E+ E
Sbjct: 414 LLPSCEIAVTRKVVQVYRKWILQ-DKPVFMEEPDR----------------KDVAQEDAE 456
Query: 480 K------REEENGTNTADHVRNSSWAKNGSYQGAL-HNASEEATEQNIRAGTQAVLQVFI 532
K +E + ++ H R+SSW + S+ A+ E N++AG QA+LQVF+
Sbjct: 457 KLGFSETDSKEASSESSGHKRSSSWGRTYSFTSAMSRGCVTEEENTNVKAGVQALLQVFL 516
Query: 533 INSSNIFLLEPANEIKNLLDEHTDMCKRILNIYRYMVVQVSMDKKTWEQMLLVLLRVTES 592
NS+NIFLLEP E+ LL E D CK +L I+R M+++++M+KKTWEQML +LLR+TE+
Sbjct: 517 TNSANIFLLEPCAEVPVLLKEQVDACKAVLIIFRRMIMELTMNKKTWEQMLQILLRITEA 576
Query: 593 VLKMPSQAFLQFQGKKNMTLAGRLAGPLFQTLIVAWIKANLNVYISRELWDDLLSVLSSL 652
V++ P ++ A LAG LF+TL+VAWI+ANL VYISRELWDD L VLSSL
Sbjct: 577 VMQKPKDKQIK------DLFAQSLAGLLFRTLMVAWIRANLCVYISRELWDDFLGVLSSL 630
Query: 653 TYWEELATEWSLTMETLTKVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGVGHEFQK-VS 711
T WEEL EW+ M++LT VLAR +Y +++++LPLDKLSEQK+KK +GKG + QK +
Sbjct: 631 TEWEELINEWANIMDSLTAVLARTVYGVEMTNLPLDKLSEQKEKKQRGKGCVLDPQKGTT 690
Query: 712 VDKSFSRGWSRDQPGQAPMRQRSATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVRH 771
V +SFS W PMR RSATT+G+PG EKAR+IVRQK ++++ Q
Sbjct: 691 VGRSFSLSWRSHPDVTEPMRFRSATTSGAPGVEKARNIVRQKATEVEECQ---------- 740
Query: 772 FSQSEETGNEVFGAL--NEEQPLPRSSSTSDILEPFTVERAKVNKEDMSQKLPPLNSDIG 829
QSE G L ++Q + RSSSTSDI EP + ++ K + +Q
Sbjct: 741 --QSENAPAAGSGHLTVGQQQQVLRSSSTSDIPEPLCSDSSQGQKAENTQ---------- 788
Query: 830 GSSANVPDLMDEFIAERLRSGNAST-MTRRGSSPGSLEIPKDLPDILNK 877
SS++ P + E R T + RR SSP L++ DL K
Sbjct: 789 NSSSSEPQPIQENKGHVKREHEGITILVRRSSSPAELDLKDDLQQTQGK 837
>gi|116256350 tuberous sclerosis 2 isoform 4 [Homo sapiens]
Length = 1740
Score = 99.8 bits (247), Expect = 2e-20
Identities = 70/260 (26%), Positives = 128/260 (49%), Gaps = 13/260 (5%)
Query: 1785 LLKKNEKLLRELRNLDSRQCRETHKIAVFYVAEGQEDKH-SILTNTGGSQAYEDFVAGLG 1843
L +++ R ++ LD +THKIAV YV EGQ + +IL+N GS Y +F+ GLG
Sbjct: 1453 LPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLG 1512
Query: 1844 WEVNLTNHCG----FMGGLQKNKSTGLTTPYFATSTVEVIFHVSTRMPS-DSDDSLTKKL 1898
+ L + C ++GGL G T + ++ +FH++T MP+ D D K
Sbjct: 1513 RLIELKD-CQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKK 1571
Query: 1899 RHLGNDEVHIVWSEHTRDYRRGIIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLF 1958
RHLGND V IV+++ D++ G I +F V +++ P+ + + + ++
Sbjct: 1572 RHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTS 1631
Query: 1959 DGAIVNGKVLPIMVRATAINASRALK------SLIPLYQNFYEERARYLQTIVQHHLEPT 2012
IV+ + LP + R A++A+ A + + +Y + + R R+++ + Q E
Sbjct: 1632 VAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEA 1691
Query: 2013 TFEDFAAQVFSPAPYHHLPS 2032
+ + + + P + P+
Sbjct: 1692 AYSNPSLPLVHPPSHSKAPA 1711
>gi|116256352 tuberous sclerosis 2 isoform 1 [Homo sapiens]
Length = 1807
Score = 99.8 bits (247), Expect = 2e-20
Identities = 70/260 (26%), Positives = 128/260 (49%), Gaps = 13/260 (5%)
Query: 1785 LLKKNEKLLRELRNLDSRQCRETHKIAVFYVAEGQEDKH-SILTNTGGSQAYEDFVAGLG 1843
L +++ R ++ LD +THKIAV YV EGQ + +IL+N GS Y +F+ GLG
Sbjct: 1520 LPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLG 1579
Query: 1844 WEVNLTNHCG----FMGGLQKNKSTGLTTPYFATSTVEVIFHVSTRMPS-DSDDSLTKKL 1898
+ L + C ++GGL G T + ++ +FH++T MP+ D D K
Sbjct: 1580 RLIELKD-CQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKK 1638
Query: 1899 RHLGNDEVHIVWSEHTRDYRRGIIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLF 1958
RHLGND V IV+++ D++ G I +F V +++ P+ + + + ++
Sbjct: 1639 RHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTS 1698
Query: 1959 DGAIVNGKVLPIMVRATAINASRALK------SLIPLYQNFYEERARYLQTIVQHHLEPT 2012
IV+ + LP + R A++A+ A + + +Y + + R R+++ + Q E
Sbjct: 1699 VAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEA 1758
Query: 2013 TFEDFAAQVFSPAPYHHLPS 2032
+ + + + P + P+
Sbjct: 1759 AYSNPSLPLVHPPSHSKAPA 1778
>gi|167412124 tuberous sclerosis 2 isoform 5 [Homo sapiens]
Length = 1784
Score = 99.8 bits (247), Expect = 2e-20
Identities = 70/260 (26%), Positives = 128/260 (49%), Gaps = 13/260 (5%)
Query: 1785 LLKKNEKLLRELRNLDSRQCRETHKIAVFYVAEGQEDKH-SILTNTGGSQAYEDFVAGLG 1843
L +++ R ++ LD +THKIAV YV EGQ + +IL+N GS Y +F+ GLG
Sbjct: 1497 LPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLG 1556
Query: 1844 WEVNLTNHCG----FMGGLQKNKSTGLTTPYFATSTVEVIFHVSTRMPS-DSDDSLTKKL 1898
+ L + C ++GGL G T + ++ +FH++T MP+ D D K
Sbjct: 1557 RLIELKD-CQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKK 1615
Query: 1899 RHLGNDEVHIVWSEHTRDYRRGIIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLF 1958
RHLGND V IV+++ D++ G I +F V +++ P+ + + + ++
Sbjct: 1616 RHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTS 1675
Query: 1959 DGAIVNGKVLPIMVRATAINASRALK------SLIPLYQNFYEERARYLQTIVQHHLEPT 2012
IV+ + LP + R A++A+ A + + +Y + + R R+++ + Q E
Sbjct: 1676 VAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEA 1735
Query: 2013 TFEDFAAQVFSPAPYHHLPS 2032
+ + + + P + P+
Sbjct: 1736 AYSNPSLPLVHPPSHSKAPA 1755
>gi|207448705 GTPase activating Rap/RanGAP domain-like 3 [Homo
sapiens]
Length = 1013
Score = 84.0 bits (206), Expect = 1e-15
Identities = 56/197 (28%), Positives = 101/197 (51%), Gaps = 13/197 (6%)
Query: 1768 LLSILGMNSWDK--RRSFHLLKKNEKLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSI 1825
+LS + ++ ++K R FH ++ ++L L+ ++ K V + +GQ +
Sbjct: 166 ILSAMNLDKFEKGPREIFH-----PEIQKDLLVLEEQEGSVNFKFGVLFAKDGQLTDDEM 220
Query: 1826 LTNTGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQ-KNKSTGLTTPYFATSTVEVIFHVST 1884
+N GS+ ++ F+ LG + L G+ GGL KN +TG+ + Y E++FHVST
Sbjct: 221 FSNEIGSEPFQKFLNLLGDTITLKGWTGYRGGLDTKNDTTGIHSVYTVYQGHEIMFHVST 280
Query: 1885 RMP-SDSDDSLTKKLRHLGNDEVHIVWSEHTRD---YRRGIIPTEFGDVL-IVIYPMKNH 1939
+P S + ++ RH+GND V IV+ E ++ +I + F + +V Y +N
Sbjct: 281 MLPYSKENKQQVERKRHIGNDIVTIVFQEGEESSPAFKPSMIRSHFTHIFALVRYNQQND 340
Query: 1940 MFSIQIMKKPEVPFFGP 1956
+ ++I + VP FGP
Sbjct: 341 NYRLKIFSEESVPLFGP 357
>gi|224809582 RAP1 GTPase activating protein isoform c [Homo sapiens]
Length = 663
Score = 77.0 bits (188), Expect = 2e-13
Identities = 59/224 (26%), Positives = 99/224 (44%), Gaps = 8/224 (3%)
Query: 1791 KLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTN 1850
K R + D K V Y GQ + + + S A+ +F+ LG +V L +
Sbjct: 176 KASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQD 235
Query: 1851 HCGFMGGLQ-KNKSTGLTTPYFATSTVEVIFHVSTRMP-SDSDDSLTKKLRHLGNDEVHI 1908
GF GGL + TG + Y E++FHVST++P ++ D ++ RH+GND V +
Sbjct: 236 FKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAV 295
Query: 1909 VWSEHTRDYRRGIIPTEFGDVLIVIYP----MKNHMFSIQIMKKPEVPFFG-PLFDGAIV 1963
V+ + + +I + F +V+ ++ + + + +VPFFG PL D A+
Sbjct: 296 VFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVF 355
Query: 1964 -NGKVLPIMVRATAINASRALKSLIPLYQNFYEERARYLQTIVQ 2006
G + INA A + RA L+T+ +
Sbjct: 356 RKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYE 399
>gi|224809578 RAP1 GTPase activating protein isoform a [Homo sapiens]
Length = 727
Score = 77.0 bits (188), Expect = 2e-13
Identities = 59/224 (26%), Positives = 99/224 (44%), Gaps = 8/224 (3%)
Query: 1791 KLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTN 1850
K R + D K V Y GQ + + + S A+ +F+ LG +V L +
Sbjct: 240 KASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQD 299
Query: 1851 HCGFMGGLQ-KNKSTGLTTPYFATSTVEVIFHVSTRMP-SDSDDSLTKKLRHLGNDEVHI 1908
GF GGL + TG + Y E++FHVST++P ++ D ++ RH+GND V +
Sbjct: 300 FKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAV 359
Query: 1909 VWSEHTRDYRRGIIPTEFGDVLIVIYP----MKNHMFSIQIMKKPEVPFFG-PLFDGAIV 1963
V+ + + +I + F +V+ ++ + + + +VPFFG PL D A+
Sbjct: 360 VFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVF 419
Query: 1964 -NGKVLPIMVRATAINASRALKSLIPLYQNFYEERARYLQTIVQ 2006
G + INA A + RA L+T+ +
Sbjct: 420 RKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYE 463
>gi|224809573 RAP1 GTPase activating protein isoform b [Homo sapiens]
Length = 681
Score = 77.0 bits (188), Expect = 2e-13
Identities = 59/224 (26%), Positives = 99/224 (44%), Gaps = 8/224 (3%)
Query: 1791 KLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTN 1850
K R + D K V Y GQ + + + S A+ +F+ LG +V L +
Sbjct: 176 KASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQD 235
Query: 1851 HCGFMGGLQ-KNKSTGLTTPYFATSTVEVIFHVSTRMP-SDSDDSLTKKLRHLGNDEVHI 1908
GF GGL + TG + Y E++FHVST++P ++ D ++ RH+GND V +
Sbjct: 236 FKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAV 295
Query: 1909 VWSEHTRDYRRGIIPTEFGDVLIVIYP----MKNHMFSIQIMKKPEVPFFG-PLFDGAIV 1963
V+ + + +I + F +V+ ++ + + + +VPFFG PL D A+
Sbjct: 296 VFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVF 355
Query: 1964 -NGKVLPIMVRATAINASRALKSLIPLYQNFYEERARYLQTIVQ 2006
G + INA A + RA L+T+ +
Sbjct: 356 RKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYE 399
>gi|156086740 GTPase activating Rap/RanGAP domain-like 4 isoform 2
[Homo sapiens]
Length = 715
Score = 75.5 bits (184), Expect = 5e-13
Identities = 47/163 (28%), Positives = 79/163 (48%), Gaps = 6/163 (3%)
Query: 1800 DSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQ 1859
D + T K V Y Q + + N S A+++F+ LG + L + GF GGL
Sbjct: 237 DEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLD 296
Query: 1860 -KNKSTGLTTPYFATSTVEVIFHVSTRMP-SDSDDSLTKKLRHLGNDEVHIVWSEHTRDY 1917
+ TG+ + Y E++FHVST++P +D D ++ RH+GND V I++ E +
Sbjct: 297 VTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIVAIIFQEENTPF 356
Query: 1918 RRGIIPTEFGDVLIVIY----PMKNHMFSIQIMKKPEVPFFGP 1956
+I + F IV+ + + + + + +VP FGP
Sbjct: 357 VPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGP 399
>gi|156086724 GTPase activating Rap/RanGAP domain-like 4 isoform 1
[Homo sapiens]
Length = 730
Score = 75.5 bits (184), Expect = 5e-13
Identities = 47/163 (28%), Positives = 79/163 (48%), Gaps = 6/163 (3%)
Query: 1800 DSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQ 1859
D + T K V Y Q + + N S A+++F+ LG + L + GF GGL
Sbjct: 252 DEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLD 311
Query: 1860 -KNKSTGLTTPYFATSTVEVIFHVSTRMP-SDSDDSLTKKLRHLGNDEVHIVWSEHTRDY 1917
+ TG+ + Y E++FHVST++P +D D ++ RH+GND V I++ E +
Sbjct: 312 VTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIVAIIFQEENTPF 371
Query: 1918 RRGIIPTEFGDVLIVIY----PMKNHMFSIQIMKKPEVPFFGP 1956
+I + F IV+ + + + + + +VP FGP
Sbjct: 372 VPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGP 414
>gi|112421013 signal-induced proliferation-associated 1 like 2 [Homo
sapiens]
Length = 1722
Score = 74.3 bits (181), Expect = 1e-12
Identities = 63/235 (26%), Positives = 101/235 (42%), Gaps = 11/235 (4%)
Query: 1791 KLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTN 1850
K+ +L LD + HKI + Y GQ + + N A+E+F+ LG V L
Sbjct: 590 KVSEQLLKLDEQGLSFQHKIGILYCKAGQSTEEEMYNNETAGPAFEEFLDLLGQRVRLKG 649
Query: 1851 HCGFMGGL-QKNKSTGLTTPYFATSTVEVIFHVSTRMP--SDSDDSLTKKLRHLGNDEVH 1907
+ L K STG + Y E++FHVST +P ++ L +K RH+GND V
Sbjct: 650 FSKYRAQLDNKTDSTGTHSLYTTYKDYELMFHVSTLLPYMPNNRQQLLRK-RHIGNDIVT 708
Query: 1908 IVWSE-HTRDYRRGIIPTEFGDVLIVIYP----MKNHMFSIQIMKKPEVPFFGPLFDGAI 1962
IV+ E + I + F V +++ +N +S+ + + +VP FGP +
Sbjct: 709 IVFQEPGALPFTPKSIRSHFQHVFVIVKVHNPCTENVCYSVGVSRSKDVPPFGPPIPKGV 768
Query: 1963 VNGK--VLPIMVRATAINASRALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFE 2015
K V + A INA A R YL+ + ++ + T +
Sbjct: 769 TFPKSAVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAENFVTTATVD 823
>gi|7662126 signal-induced proliferation-associated 1 like 1 [Homo
sapiens]
Length = 1804
Score = 73.2 bits (178), Expect = 2e-12
Identities = 60/235 (25%), Positives = 101/235 (42%), Gaps = 11/235 (4%)
Query: 1791 KLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTN 1850
K+ +L LD + K+ + Y GQ + + N A+E+F+ LG V L
Sbjct: 594 KVTEQLMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKG 653
Query: 1851 HCGFMGGLQ-KNKSTGLTTPYFATSTVEVIFHVSTRMP--SDSDDSLTKKLRHLGNDEVH 1907
+ L K STG + Y E++FHVST +P ++ L +K RH+GND V
Sbjct: 654 FEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRK-RHIGNDIVT 712
Query: 1908 IVWSE-HTRDYRRGIIPTEFGDVLIVI---YPMKNHM-FSIQIMKKPEVPFFGPLFDGAI 1962
IV+ E + + I + F V +++ P + + +S+ + + +VP FGP +
Sbjct: 713 IVFQEPGAQPFSPKNIRSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPKGV 772
Query: 1963 V--NGKVLPIMVRATAINASRALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFE 2015
V + A INA A R YL+ + + ++ T +
Sbjct: 773 TFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPID 827
>gi|71143119 signal-induced proliferation-associated 1 like 3 [Homo
sapiens]
Length = 1781
Score = 71.6 bits (174), Expect = 7e-12
Identities = 60/235 (25%), Positives = 101/235 (42%), Gaps = 11/235 (4%)
Query: 1791 KLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTN 1850
K+ +L LD + HK+ + Y GQ + + N A+E+F++ +G +V L
Sbjct: 606 KVTEQLLKLDEQGLCRKHKVGILYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEKVCLKG 665
Query: 1851 HCGFMGGLQ-KNKSTGLTTPYFATSTVEVIFHVSTRMP--SDSDDSLTKKLRHLGNDEVH 1907
+ L K STG + Y E++FHVST +P ++ L +K RH+GND V
Sbjct: 666 FTKYAAQLDVKTDSTGTHSLYTMYQDYEIMFHVSTLLPYTPNNRQQLLRK-RHIGNDIVT 724
Query: 1908 IVWSE-HTRDYRRGIIPTEFGDVLIVIYP----MKNHMFSIQIMKKPEVPFFGPLFDGAI 1962
I++ E + I + F V I++ N +S+ + + + P FGP
Sbjct: 725 IIFQEPGALPFTPKNIRSHFQHVFIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPIPSGT 784
Query: 1963 VNGK--VLPIMVRATAINASRALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFE 2015
K V + A INA A + R YL+ + ++ + T +
Sbjct: 785 TFRKSDVFRDFLLAKVINAENAAHKSDKFHTMATRTRQEYLKDLAENCVSNTPID 839
>gi|206725526 signal-induced proliferation-associated protein 1 [Homo
sapiens]
Length = 1042
Score = 67.4 bits (163), Expect = 1e-10
Identities = 60/236 (25%), Positives = 99/236 (41%), Gaps = 12/236 (5%)
Query: 1791 KLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTN 1850
K+ R L LD + K+ + Y GQ + + N A+ F+ LG V L
Sbjct: 316 KVPRTLLTLDEQVLSFQRKVGILYCRAGQGSEEEMYNNQEAGPAFMQFLTLLGDVVRLKG 375
Query: 1851 HCGFMGGLQ-KNKSTGLTTPYFATSTVEVIFHVSTRMP--SDSDDSLTKKLRHLGNDEVH 1907
+ L K STG + Y E++FHVST +P ++ L +K RH+GND V
Sbjct: 376 FESYRAQLDTKTDSTGTHSLYTTYQDHEIMFHVSTMLPYTPNNQQQLLRK-RHIGNDIVT 434
Query: 1908 IVWSE-HTRDYRRGIIPTEFGDVLIVI---YPMKNH-MFSIQIMKKPEVPFFGPLF---D 1959
IV+ E ++ + I + F V +V+ P H + + + + + P FGP
Sbjct: 435 IVFQEPGSKPFCPTTIRSHFQHVFLVVRAHTPCTPHTTYRVAVSRTQDTPAFGPALPAGG 494
Query: 1960 GAIVNGKVLPIMVRATAINASRALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFE 2015
G + A A+N +A + R +YLQ + + + T+ +
Sbjct: 495 GPFAANADFRAFLLAKALNGEQAAGHARQFHAMATRTRQQYLQDLATNEVTTTSLD 550
>gi|206725523 signal-induced proliferation-associated protein 1 [Homo
sapiens]
Length = 1042
Score = 67.4 bits (163), Expect = 1e-10
Identities = 60/236 (25%), Positives = 99/236 (41%), Gaps = 12/236 (5%)
Query: 1791 KLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTN 1850
K+ R L LD + K+ + Y GQ + + N A+ F+ LG V L
Sbjct: 316 KVPRTLLTLDEQVLSFQRKVGILYCRAGQGSEEEMYNNQEAGPAFMQFLTLLGDVVRLKG 375
Query: 1851 HCGFMGGLQ-KNKSTGLTTPYFATSTVEVIFHVSTRMP--SDSDDSLTKKLRHLGNDEVH 1907
+ L K STG + Y E++FHVST +P ++ L +K RH+GND V
Sbjct: 376 FESYRAQLDTKTDSTGTHSLYTTYQDHEIMFHVSTMLPYTPNNQQQLLRK-RHIGNDIVT 434
Query: 1908 IVWSE-HTRDYRRGIIPTEFGDVLIVI---YPMKNH-MFSIQIMKKPEVPFFGPLF---D 1959
IV+ E ++ + I + F V +V+ P H + + + + + P FGP
Sbjct: 435 IVFQEPGSKPFCPTTIRSHFQHVFLVVRAHTPCTPHTTYRVAVSRTQDTPAFGPALPAGG 494
Query: 1960 GAIVNGKVLPIMVRATAINASRALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFE 2015
G + A A+N +A + R +YLQ + + + T+ +
Sbjct: 495 GPFAANADFRAFLLAKALNGEQAAGHARQFHAMATRTRQQYLQDLATNEVTTTSLD 550
>gi|34787409 hypothetical protein LOC57148 [Homo sapiens]
Length = 1494
Score = 62.8 bits (151), Expect = 3e-09
Identities = 88/380 (23%), Positives = 147/380 (38%), Gaps = 92/380 (24%)
Query: 1505 AARTVITHLVNHLGHYPMSGGPAMLTSQVCENHDNHYSESTELSPELFESPNIQFFVLNN 1564
AA +T ++ LG +P GPA S V E YS ++ F ++FVL+N
Sbjct: 898 AAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSRLPTINKHSF-----RYFVLDN 952
Query: 1565 TTLVSCIQ--IRSEENMPGGGLSAGLASANSNVRIIVRDLSGKYSWDSAI---------- 1612
+ +++ ++ + +E+N +V ++VR +SG+ +W +
Sbjct: 953 SVILAMLEQPLGNEQN-----------DFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKAN 1001
Query: 1613 --LYGPPPVSGLSEPTSFMLSLSHQEKPEEPPTSNECLEDITVKDGLSLQFKRFRETVPT 1670
L+ P P F S+ H+ PEE + F + ++P
Sbjct: 1002 QKLFVPEPRPVPKNDVGFKYSVKHRPFPEEVD---------------KIPFVKADLSIPD 1046
Query: 1671 WDTIRDEEDVLDELLQYLGVTSPECLQRTGISLNIPAPQPVCISEKQENDVINAILKQHT 1730
I EE L+E + L R+G++ I L+Q +
Sbjct: 1047 LHEIVTEE--LEERHEKL---------RSGMAQQI---------------AYEIHLEQQS 1080
Query: 1731 EEKEFVEKHFNDLNMKAVEQDEPIPQKPQSAFYYCRLLLSILGMNSWD-------KRRSF 1783
EE E ++ F D V +P P P F RL LS G S + R
Sbjct: 1081 EE-ELQKRSFPD----PVTDCKPPP--PAQEFQTARLFLSHFGFLSLEALKEPANSRLPP 1133
Query: 1784 HLLKKNEKL---LRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYE---- 1836
HL+ + + ++ LD CR + +FY+ GQ+ IL N S+ +
Sbjct: 1134 HLIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNVESSRTVQPHFL 1193
Query: 1837 DFVAGLGWEVNLTNHCGFMG 1856
+F+ LGW V++ H G+ G
Sbjct: 1194 EFLLSLGWSVDVGRHPGWTG 1213
Score = 42.7 bits (99), Expect = 0.004
Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 10/123 (8%)
Query: 557 MCKRILNIYRYMVVQVS-MDKKTWEQMLLVLLRVTESVLKMPSQAFLQFQGKKNMTLAGR 615
+C ++L + + + S M ++TWE +LL LL++ + +L P+ QG LA +
Sbjct: 140 LCLQVLRAIQKLARESSLMARETWEVLLLFLLQINDILLAPPT-----VQGGIAENLAEK 194
Query: 616 LAGPLFQTLIVAWIKANLNVYISRELWDDLLSVLSSLTYWEELATEWSLTMETLTKVLAR 675
L G LF+ W+ A + + W ++++ + + +WS + LT L R
Sbjct: 195 LIGVLFEV----WLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLR 250
Query: 676 NLY 678
Y
Sbjct: 251 FTY 253
Score = 33.9 bits (76), Expect = 1.7
Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 1/94 (1%)
Query: 1930 LIVIYPMKNHMFSIQIMKKP-EVPFFGPLFDGAIVNGKVLPIMVRATAINASRALKSLIP 1988
+I I+P+ +F I+I + PL DG IV+ + L +VR T IN R +
Sbjct: 1391 VIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESD 1450
Query: 1989 LYQNFYEERARYLQTIVQHHLEPTTFEDFAAQVF 2022
Y + R + + IV + +F +F
Sbjct: 1451 SYSPPHVRRKQKITDIVNKYRNKQLEPEFYTSLF 1484
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 40.4 bits (93), Expect = 0.018
Identities = 53/300 (17%), Positives = 106/300 (35%), Gaps = 3/300 (1%)
Query: 721 SRDQPGQAPMRQRSATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVRHFSQSEETGN 780
S+ + S + S + + S + D D+ S+ S S ++ N
Sbjct: 638 SKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSN 697
Query: 781 EVFGALNEEQPLPRSSSTSDILEPFTVERAKVNKEDMSQKLPPLNSDIGGSSANVPDLMD 840
+ + + SS +SD + + N D S +S S+N D D
Sbjct: 698 SSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSD 757
Query: 841 EFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAG 900
+ + S+ + S + D + + + D S S+
Sbjct: 758 SSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817
Query: 901 SSDLISSDSHS---DSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQSAEEQEVA 957
S SSDS + S S+ D + G+D+ ++ +D + S S++ +
Sbjct: 818 SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS 877
Query: 958 SLTTLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNIDHMEQKD 1017
+ +E+S+ + + S+ + S+S++ S S S S S+ + D+ D
Sbjct: 878 DSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD 937
Score = 37.0 bits (84), Expect = 0.20
Identities = 40/195 (20%), Positives = 74/195 (37%), Gaps = 2/195 (1%)
Query: 825 NSDIGGSSANVPDLMDEFIAERLRS--GNASTMTRRGSSPGSLEIPKDLPDILNKQNQMR 882
NSD G+ N D D+ + + +S ++ + SS S D D + +
Sbjct: 523 NSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDS 582
Query: 883 PIDDPGVPSEWTSPASAGSSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVD 942
D S+ S S+ SSD S SDS + K D+ +D+ + S
Sbjct: 583 SDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDS 642
Query: 943 SGSGHHQSAEEQEVASLTTLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQT 1002
S S S++ + + + S++S + + S+ + + S +S S +
Sbjct: 643 SDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESS 702
Query: 1003 PSPSTLNIDHMEQKD 1017
S + + D + D
Sbjct: 703 DSSDSSDSDSSDSSD 717
Score = 37.0 bits (84), Expect = 0.20
Identities = 41/205 (20%), Positives = 79/205 (38%), Gaps = 1/205 (0%)
Query: 813 NKEDMSQKLPPLNSDIGGSSANVPDLMDEFIAERLRSGNASTMTRRGSSPGSLEIPKDLP 872
N D S +S S++ D D + S N+S + +S S + D
Sbjct: 790 NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSD-SSDSS 848
Query: 873 DILNKQNQMRPIDDPGVPSEWTSPASAGSSDLISSDSHSDSFSAFQYDGRKFDNFGFGTD 932
D + + R S +S +S S SSDS+ S S+ D +
Sbjct: 849 DGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDS 908
Query: 933 TGVTSSADVDSGSGHHQSAEEQEVASLTTLHIDSETSSLNQQAFSAEVATITGSESASPV 992
+ + S+D + S +S+ + ++ + S++S + + S++ + + S ++S
Sbjct: 909 SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDS 968
Query: 993 HSPLGSRSQTPSPSTLNIDHMEQKD 1017
S S S S+ + D + D
Sbjct: 969 SDSNSSDSSDSSNSSDSSDSSDSSD 993
Score = 34.3 bits (77), Expect = 1.3
Identities = 48/228 (21%), Positives = 87/228 (38%), Gaps = 6/228 (2%)
Query: 795 SSSTSDILEPFTVERAKVNKEDMSQKLPPLNSDIGGSSANVPDLMD-EFIAERLRSGNAS 853
SSS SD + + + + + D S +S S++ D D + + + S ++
Sbjct: 576 SSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSD 635
Query: 854 TMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAGSSDLI----SSDS 909
+ ++ SS + D D + N D S +S+ SS+ SSDS
Sbjct: 636 SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS 695
Query: 910 HSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQSAEEQEVASLTTLHIDSETS 969
+ S S+ D D+ +D+ ++S+D DS + S S + + +
Sbjct: 696 SNSSESSDSSDSSDSDSSD-SSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSD 754
Query: 970 SLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNIDHMEQKD 1017
S + S + S+S+ S S S S S+ + D D
Sbjct: 755 SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSD 802
Score = 34.3 bits (77), Expect = 1.3
Identities = 50/223 (22%), Positives = 84/223 (37%), Gaps = 15/223 (6%)
Query: 795 SSSTSDILEPFTVERAKVNKEDMSQKLPPLNSDIGGSSANVPDLMDEFIAERLRSGNAST 854
SS++SD + + N D S +SD SS + ++ S N+S
Sbjct: 873 SSNSSDSSDSSDSNESS-NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931
Query: 855 MTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAGSSDLISSDSHSDSF 914
+ S S + D D N + D S S+ SSD SSDS S
Sbjct: 932 NSNSSDSSNSSD-SSDSSDSSNSSDSSNSSD---------SSNSSDSSDSNSSDSSDSSN 981
Query: 915 SAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQSAEEQEVASLTTLHIDSETSSLNQQ 974
S+ D + +D+ +S + S S ++ + +S ++ DS SS +
Sbjct: 982 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041
Query: 975 AFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNIDHMEQKD 1017
+ + S+S+ +S S S S S+ + D + D
Sbjct: 1042 SSDSS----DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080
Score = 32.7 bits (73), Expect = 3.7
Identities = 50/248 (20%), Positives = 90/248 (36%), Gaps = 13/248 (5%)
Query: 773 SQSEETGNEVFGALNEEQPLPRSSSTSDILEPFTVERAKVNKEDMSQKLPPLNSDIGGSS 832
S S ++ N + + + SS +SD N D S +S S
Sbjct: 951 SNSSDSSNSSDSSNSSDSSDSNSSDSSD----------SSNSSDSSDSSDSSDSSDSSDS 1000
Query: 833 ANVPDLMDEFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSE 892
+N D D + + + S+ + S+ D D + + D
Sbjct: 1001 SNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1060
Query: 893 WTSPASAGSSDLISSDSHSDSF-SAFQYDGRKFDNFGFGTDTGVTS-SADVDSGSGHHQS 950
S S+ SSD S SDS S+ D + +D+ +S S+D S S
Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1120
Query: 951 AEEQEVASLTTLHIDSETSSLNQQAFSAEVA-TITGSESASPVHSPLGSRSQTPSPSTLN 1009
+ + + + S++S+ + + S+E + + S+S+ S S S S S+ +
Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1180
Query: 1010 IDHMEQKD 1017
D + D
Sbjct: 1181 SDSSDSSD 1188
Score = 31.6 bits (70), Expect = 8.3
Identities = 43/233 (18%), Positives = 77/233 (33%), Gaps = 6/233 (2%)
Query: 721 SRDQPGQAPMRQRSATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVRHFSQSEETGN 780
S D + S ++ S ++ + S + D D+ S+ S S ++ +
Sbjct: 1075 SSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1134
Query: 781 EVFGALNEEQPLPRSSSTSDILEPFTVERAKVNKEDMSQKLPPLNSDIGGSSANVPDLMD 840
+ + + SS S + + D S NS S++ D D
Sbjct: 1135 SSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1194
Query: 841 EFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAG 900
+ + S+ + S D D + D S S+
Sbjct: 1195 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSD 1254
Query: 901 SSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQSAEE 953
SSD SSDS SDS + G G + G S +D + +H ++++
Sbjct: 1255 SSD--SSDSTSDSNDESDSQSKS----GNGNNNGSDSDSDSEGSDSNHSTSDD 1301
>gi|150456424 RW1 protein [Homo sapiens]
Length = 1883
Score = 39.3 bits (90), Expect = 0.040
Identities = 58/261 (22%), Positives = 92/261 (35%), Gaps = 61/261 (23%)
Query: 689 KLSEQKQKKHKGKGVGHEFQKVSVDKSFSRGWSRDQPGQAPMRQRSATTTGSPGTEKARS 748
K E+K+KK KGK E + D S + T T +P TE
Sbjct: 1395 KKQEEKEKKGKGKPQEDELKDSLADDDSSS---------------TTTETSNPDTEP--- 1436
Query: 749 IVRQKTVDIDDAQILPRSTRVRHFSQSEETGNEVFGALNEEQPLPRSSSTSDILEPFTVE 808
++++ T Q +P +H S+ + + LN ++ +P S + P+T
Sbjct: 1437 LLKEDTEKQKGKQAMPE----KHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPP 1492
Query: 809 RAKVNKEDMSQKLPPLNSDIGGSSA--------------NVPDLMDEFIAERLRSGNAST 854
+ ++ K+P + GS + N P + +F+ GN S+
Sbjct: 1493 LESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNTSS 1552
Query: 855 MTRRGSS------------PGS-------LEIPKDLPDILNKQNQMRPIDDPGVPSEWTS 895
S PGS L + DI KQ Q P P PS +
Sbjct: 1553 SEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSP--TPASPSPPAA 1610
Query: 896 P----ASAGSSDLISSDSHSD 912
P A S +++S S SD
Sbjct: 1611 PCPFVARGSYSSIVNSSSSSD 1631
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 38.5 bits (88), Expect = 0.068
Identities = 75/334 (22%), Positives = 117/334 (35%), Gaps = 57/334 (17%)
Query: 721 SRDQPGQAPMRQRSATTTGSPGTEKARSIVRQKTVDIDDAQILPRS--TRVR------HF 772
SR QPG A+TT +PG + + V + + + PR+ T VR
Sbjct: 2358 SRSQPGSTHSTVSPASTT-TPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFH 2416
Query: 773 SQSEETGNEVF-------GALNEEQPLPRSSSTSDILEPFTVERAKVNKEDMSQKLPPLN 825
S+ T +F G E P S +++ P T+ A + +E S P +
Sbjct: 2417 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEE--STTFPSSS 2474
Query: 826 SDIGGSSANVPDLMDEFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPID 885
G + + + E S + + T + PGS P + K
Sbjct: 2475 GSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS----PTTPSLSEKSTTF--YT 2528
Query: 886 DPGVPSEWTSPASAGSSDLI--SSDSHSDSFSAF--------------QYDGRKFDNFGF 929
P P SPA+ SS + SS SHS S ++ + G
Sbjct: 2529 SPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG- 2587
Query: 930 GTDTGVTSSADVDSGSGH-----HQSAEEQEVA----SLTTLHIDSETSSLNQQAFSAEV 980
TDT + ++ SG H S + A S T L E+++ + S
Sbjct: 2588 STDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHT 2647
Query: 981 ATITGS-------ESASPVHSPLGSRSQTPSPST 1007
S E+++ VHS GS T SP++
Sbjct: 2648 TLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPAS 2681
Score = 36.2 bits (82), Expect = 0.34
Identities = 70/328 (21%), Positives = 116/328 (35%), Gaps = 36/328 (10%)
Query: 690 LSEQKQKKHKGKGVGHEFQKVSVDKSFSRGWSRDQPGQAPMRQRSATTTGSPGTEKARSI 749
+SE+ H G H D + + G S++ P + Q S T SPG+ A S+
Sbjct: 4104 VSEESSTSHSQPGSTHT--TAFPDSTTTSGLSQE-PTTSHSSQGSTEATLSPGSTTASSL 4160
Query: 750 VRQKTV-----DIDDAQILPRSTRVRHFSQSEETGNEVFGALNEEQPLPRSSSTSDILEP 804
+Q T + +LP T ++ + G+L+ P SS+++ + E
Sbjct: 4161 GQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT-PASSTSTGLQEE 4219
Query: 805 FTVERAKVNKEDMSQKLP-----PLNSDIGGSSANVPDLMDEFIAERLRSGNASTMTRRG 859
T ++ + D + P P+ S F A G + T
Sbjct: 4220 STTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVH 4279
Query: 860 SSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAGSSDLISSDSHSDSFSAFQY 919
SSPG+ R V TSP S+GS++ + S + +
Sbjct: 4280 SSPGATG---------TALFPTRSATSVLVGEPTTSPISSGSTETTALPG-STTTAGLSE 4329
Query: 920 DGRKFDNFGFGTDTGVTSSADVDSGSGHHQSAEEQEVASLTTLHIDSETSSLNQQAFSAE 979
F + DT ++ ++ SG TT H S S++ AF +
Sbjct: 4330 KSTTFYSSPRSPDTTLSPASTTSSGVSEES----------TTSH--SRPGSMHTTAFPSS 4377
Query: 980 VATITGSESASPVHSPLGSRSQTPSPST 1007
S+ ++ HS GS T SP +
Sbjct: 4378 TTMPGVSQESTASHSSPGSTDTTLSPGS 4405
Score = 33.5 bits (75), Expect = 2.2
Identities = 66/323 (20%), Positives = 99/323 (30%), Gaps = 55/323 (17%)
Query: 721 SRDQPGQAPMRQRSATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVRHFSQSEETGN 780
SR QPG A+TT +PG + + V + + + PRST + E T
Sbjct: 3915 SRSQPGSTHSTVSPASTT-TPGLSEESTTVYSSSPGSTETTVFPRSTTTS-VRREEPTTF 3972
Query: 781 EVFGALNEEQPLPRSSSTSDILEPFTVERAKVNKEDMSQKLPPLNSDIGGSSANVPDLMD 840
A S+TS + E T +D+G S P
Sbjct: 3973 HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPS--- 4029
Query: 841 EFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAG 900
SG+ T S S + + P L+ PS + G
Sbjct: 4030 -------SSGSTGTKLSPARSTTSGLVGESTPSRLS-------------PSSTETTTLPG 4069
Query: 901 SSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQSAEEQEVASLT 960
S S S +F Y + + T +S +S + H
Sbjct: 4070 SPTTPSLSEKSTTF----YTSPRSPDATLSPATTTSSGVSEESSTSH------------- 4112
Query: 961 TLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNIDHMEQKDLQL 1020
S+ S + AF T S+ + HS GS T SP + + Q+
Sbjct: 4113 -----SQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTF 4167
Query: 1021 DEKLHHSVLQTPDDLEISEFPSE 1043
HS +P D E + P +
Sbjct: 4168 -----HS---SPGDTETTLLPDD 4182
Score = 33.5 bits (75), Expect = 2.2
Identities = 56/252 (22%), Positives = 86/252 (34%), Gaps = 29/252 (11%)
Query: 764 PRSTRVRHFSQS--------EETGNEVFGALNEEQPLPRSSSTSDILEPFTVERAKVNKE 815
P ST HFS S E T P P S+TS ++E T +
Sbjct: 4503 PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGST 4562
Query: 816 DMSQKLPPLNSDIGGSSANVPDLMDEFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDIL 875
+ P N+ G E + ++ST S+P + + P
Sbjct: 4563 Q-TMHFPESNTTSGRG-------------EESTTSHSSTTHTISSAPSTTSALVEEPTSY 4608
Query: 876 NKQNQMRPIDDPGVPSEWTSPASAGSSDLISSDSHSDSFSAFQYDGRKFDNFGFG-TDTG 934
+ P +S S S + +S S D+ R + G + T
Sbjct: 4609 HSS----PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTS 4664
Query: 935 VTSSADVDSGSGHHQSAEEQEVASLTTLHIDSETSSLNQQAFSAEVATITGSESASPVHS 994
SS +++ + + TT H S SS FSA T+ SE ++ VHS
Sbjct: 4665 PISSGSMETTALPGSTTTPGLSEKSTTFH--SSPSSTPTTHFSASSTTLGRSEESTTVHS 4722
Query: 995 PLGSRSQTPSPS 1006
+ + TPSP+
Sbjct: 4723 SPVATATTPSPA 4734
Score = 32.7 bits (73), Expect = 3.7
Identities = 64/291 (21%), Positives = 101/291 (34%), Gaps = 53/291 (18%)
Query: 729 PMRQRSATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVRHFSQSEETGNEVFGALNE 788
P R ++ G P T S + T LP ST S+ T
Sbjct: 1651 PTRSATSVLVGEPTTSPISSGSTETTA-------LPGSTTTAGLSEKSTTFYSS------ 1697
Query: 789 EQPLPRSSSTSDILEPFTVERAKVNKEDMSQKLPPLNSDIGG--SSANVPDLMDEFIAER 846
PRS T+ L P + + V++E + P ++ S +P + E A
Sbjct: 1698 ----PRSPDTT--LSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASH 1751
Query: 847 LRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAGSSDLIS 906
G+ T SPGS P+ + + +P T+ +S +
Sbjct: 1752 SSPGSTDTTL----SPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVH 1807
Query: 907 SDSHSD-------SFSAFQYDGRKFDNFGFGTDT----GVTSSADVDSGSGHHQSAEEQE 955
S + S + Q + F ++ DT T+SA V+ + H S
Sbjct: 1808 SSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSP---- 1863
Query: 956 VASLTTLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPS 1006
+S T H FSA T+ SE ++ VHS + + TPSP+
Sbjct: 1864 -SSTPTTH------------FSASSTTLGRSEESTTVHSSPVATATTPSPA 1901
Score = 32.3 bits (72), Expect = 4.9
Identities = 66/323 (20%), Positives = 99/323 (30%), Gaps = 55/323 (17%)
Query: 721 SRDQPGQAPMRQRSATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVRHFSQSEETGN 780
SR QPG A+TT +PG + + V + + + PRST + E T
Sbjct: 2832 SRSQPGSTHSTVSPASTT-TPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGE-EPTTF 2889
Query: 781 EVFGALNEEQPLPRSSSTSDILEPFTVERAKVNKEDMSQKLPPLNSDIGGSSANVPDLMD 840
A S+TS + E T +D+G S P
Sbjct: 2890 HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPS--- 2946
Query: 841 EFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAG 900
SG+ T S S + + P L+ PS + G
Sbjct: 2947 -------SSGSTGTTLSPARSTTSGLVGESTPSRLS-------------PSSTETTTLPG 2986
Query: 901 SSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQSAEEQEVASLT 960
S S S +F Y + + T +S +S + H
Sbjct: 2987 SPTTPSLSEKSTTF----YTSPRSPDATLSPATTTSSGVSEESSTSH------------- 3029
Query: 961 TLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNIDHMEQKDLQL 1020
S+ S + AF T S+ + HS GS T SP + + Q+
Sbjct: 3030 -----SQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTF 3084
Query: 1021 DEKLHHSVLQTPDDLEISEFPSE 1043
HS +P D E + P +
Sbjct: 3085 -----HS---SPGDTETTLLPDD 3099
Score = 31.6 bits (70), Expect = 8.3
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Query: 960 TTLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPS-TLNIDHMEQ 1015
TT H S SS FSA T+ SE ++PVHS + + TP P+ + H+E+
Sbjct: 446 TTYH--SSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEE 500
Score = 31.6 bits (70), Expect = 8.3
Identities = 64/291 (21%), Positives = 101/291 (34%), Gaps = 53/291 (18%)
Query: 729 PMRQRSATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVRHFSQSEETGNEVFGALNE 788
P R ++ G P T S + T LP ST S+ T
Sbjct: 3208 PTRSATSVLVGEPTTSPISSGSTETTA-------LPGSTTTAGLSEKSTTFYSS------ 3254
Query: 789 EQPLPRSSSTSDILEPFTVERAKVNKEDMSQKLPPLNSDIGG--SSANVPDLMDEFIAER 846
PRS T+ L P + + V++E + P ++ S +P + E A
Sbjct: 3255 ----PRSPDTT--LSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASH 3308
Query: 847 LRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAGSSDLIS 906
G+ T SPGS P+ + + +P T+ +S +
Sbjct: 3309 SSPGSTDTTL----SPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVH 3364
Query: 907 SDSHSD-------SFSAFQYDGRKFDNFGFGTDTG----VTSSADVDSGSGHHQSAEEQE 955
S + S + Q + F ++ DT T+SA V+ + H S
Sbjct: 3365 SSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSP---- 3420
Query: 956 VASLTTLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPS 1006
+S T H FSA T+ SE ++ VHS + + TPSP+
Sbjct: 3421 -SSTPTTH------------FSASSTTLGRSEESTTVHSSPVATATTPSPA 3458
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 36.6 bits (83), Expect = 0.26
Identities = 31/115 (26%), Positives = 55/115 (47%), Gaps = 9/115 (7%)
Query: 894 TSPASAGSSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTS-SADVDSGSGHHQSAE 952
+S S+G+S +S+S + S A + G T S S+ SG+G ++E
Sbjct: 200 SSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSE 259
Query: 953 EQEVASLTTLHIDSETSSLNQQAFSAEVATITGSESASP---VHSPLGSRSQTPS 1004
+S +SE+S++ S+ ++T+T SES++P ++ S S T S
Sbjct: 260 SSTTSSGAGTATNSESSTV-----SSGISTVTNSESSTPSSGANTATNSESSTTS 309
Score = 33.5 bits (75), Expect = 2.2
Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 9/116 (7%)
Query: 894 TSPASAGSSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTS-SADVDSGSGHHQSAE 952
+S S+G+S +S+S + S A GT T S S+ V SG+ ++E
Sbjct: 335 SSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSE 394
Query: 953 EQEVASLTTLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTL 1008
+S + +SE+S++ S+ +T T SES++ + G+ + T S S++
Sbjct: 395 SSTTSSGASTATNSESSTV-----SSGASTATNSESST---TSSGANTATNSGSSV 442
Score = 32.0 bits (71), Expect = 6.3
Identities = 35/157 (22%), Positives = 63/157 (40%), Gaps = 7/157 (4%)
Query: 849 SGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAGSSDLISSD 908
S A T T SS + + + N ++ + +S S+G++ +SD
Sbjct: 264 SSGAGTATNSESST----VSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSD 319
Query: 909 SHSDSFSAFQYDGRKFDNFGFGTDTGVTS-SADVDSGSGHHQSAEEQEVASLTTLHIDSE 967
S + S A + G T S S+ SG+ ++ +S T+ +SE
Sbjct: 320 SSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSE 379
Query: 968 TSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPS 1004
+S+++ A +A T S ++S + S S T S
Sbjct: 380 SSTVSSGASTA--TTSESSTTSSGASTATNSESSTVS 414
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 35.8 bits (81), Expect = 0.44
Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 10/103 (9%)
Query: 908 DSHSDSFSAFQYDGRKFDNF--GFGTDTGVTSSADVDSGSGHHQSAEEQEVASLTTLHID 965
DS+ + SA DG + D+ G GTD G + + G G+H++A+ Q T
Sbjct: 1987 DSNEGTGSADGNDGYEADDAEGGDGTDPGTETEESMGGGEGNHRAADSQNSGEGNT---- 2042
Query: 966 SETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTL 1008
+ +FS EV+ SAS +P +S P L
Sbjct: 2043 ----GAAESSFSQEVSREQQPSSASERQAPRAPQSPRRPPHPL 2081
>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 35.0 bits (79), Expect = 0.75
Identities = 39/164 (23%), Positives = 70/164 (42%), Gaps = 32/164 (19%)
Query: 891 SEWTSPASAGSSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQS 950
SE T+ ++ GS +S +HS++ +A G++T V+++ + + S
Sbjct: 202 SETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAA----S 257
Query: 951 AEEQEVASLTTLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNI 1010
E+ E + T DS+T++ + F A+ TGSE + S +G S+T ST+
Sbjct: 258 TEDSETNTAFTE--DSKTTTASTTGFETTAASTTGSEPT--MASTMG--SETTMASTIG- 310
Query: 1011 DHMEQKDLQLDEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLT 1054
P+ ++S SE +V A G+ T
Sbjct: 311 ---------------------PETTKVSTASSEVTTVFAAGSET 333
>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1521
Score = 35.0 bits (79), Expect = 0.75
Identities = 39/164 (23%), Positives = 70/164 (42%), Gaps = 32/164 (19%)
Query: 891 SEWTSPASAGSSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQS 950
SE T+ ++ GS +S +HS++ +A G++T V+++ + + S
Sbjct: 202 SETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAA----S 257
Query: 951 AEEQEVASLTTLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNI 1010
E+ E + T DS+T++ + F A+ TGSE + S +G S+T ST+
Sbjct: 258 TEDSETNTAFTE--DSKTTTASTTGFETTAASTTGSEPT--MASTMG--SETTMASTIG- 310
Query: 1011 DHMEQKDLQLDEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLT 1054
P+ ++S SE +V A G+ T
Sbjct: 311 ---------------------PETTKVSTASSEVTTVFAAGSET 333
>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1612
Score = 35.0 bits (79), Expect = 0.75
Identities = 39/164 (23%), Positives = 70/164 (42%), Gaps = 32/164 (19%)
Query: 891 SEWTSPASAGSSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQS 950
SE T+ ++ GS +S +HS++ +A G++T V+++ + + S
Sbjct: 202 SETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAA----S 257
Query: 951 AEEQEVASLTTLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNI 1010
E+ E + T DS+T++ + F A+ TGSE + S +G S+T ST+
Sbjct: 258 TEDSETNTAFTE--DSKTTTASTTGFETTAASTTGSEPT--MASTMG--SETTMASTIG- 310
Query: 1011 DHMEQKDLQLDEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLT 1054
P+ ++S SE +V A G+ T
Sbjct: 311 ---------------------PETTKVSTASSEVTTVFAAGSET 333
>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1542
Score = 35.0 bits (79), Expect = 0.75
Identities = 39/164 (23%), Positives = 70/164 (42%), Gaps = 32/164 (19%)
Query: 891 SEWTSPASAGSSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQS 950
SE T+ ++ GS +S +HS++ +A G++T V+++ + + S
Sbjct: 223 SETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAA----S 278
Query: 951 AEEQEVASLTTLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNI 1010
E+ E + T DS+T++ + F A+ TGSE + S +G S+T ST+
Sbjct: 279 TEDSETNTAFTE--DSKTTTASTTGFETTAASTTGSEPT--MASTMG--SETTMASTIG- 331
Query: 1011 DHMEQKDLQLDEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLT 1054
P+ ++S SE +V A G+ T
Sbjct: 332 ---------------------PETTKVSTASSEVTTVFAAGSET 354
>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
sapiens]
Length = 1521
Score = 35.0 bits (79), Expect = 0.75
Identities = 39/164 (23%), Positives = 70/164 (42%), Gaps = 32/164 (19%)
Query: 891 SEWTSPASAGSSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQS 950
SE T+ ++ GS +S +HS++ +A G++T V+++ + + S
Sbjct: 202 SETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAA----S 257
Query: 951 AEEQEVASLTTLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNI 1010
E+ E + T DS+T++ + F A+ TGSE + S +G S+T ST+
Sbjct: 258 TEDSETNTAFTE--DSKTTTASTTGFETTAASTTGSEPT--MASTMG--SETTMASTIG- 310
Query: 1011 DHMEQKDLQLDEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLT 1054
P+ ++S SE +V A G+ T
Sbjct: 311 ---------------------PETTKVSTASSEVTTVFAAGSET 333
>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1612
Score = 35.0 bits (79), Expect = 0.75
Identities = 39/164 (23%), Positives = 70/164 (42%), Gaps = 32/164 (19%)
Query: 891 SEWTSPASAGSSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQS 950
SE T+ ++ GS +S +HS++ +A G++T V+++ + + S
Sbjct: 202 SETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAA----S 257
Query: 951 AEEQEVASLTTLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNI 1010
E+ E + T DS+T++ + F A+ TGSE + S +G S+T ST+
Sbjct: 258 TEDSETNTAFTE--DSKTTTASTTGFETTAASTTGSEPT--MASTMG--SETTMASTIG- 310
Query: 1011 DHMEQKDLQLDEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLT 1054
P+ ++S SE +V A G+ T
Sbjct: 311 ---------------------PETTKVSTASSEVTTVFAAGSET 333
>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1704
Score = 35.0 bits (79), Expect = 0.75
Identities = 39/164 (23%), Positives = 70/164 (42%), Gaps = 32/164 (19%)
Query: 891 SEWTSPASAGSSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQS 950
SE T+ ++ GS +S +HS++ +A G++T V+++ + + S
Sbjct: 202 SETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAA----S 257
Query: 951 AEEQEVASLTTLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNI 1010
E+ E + T DS+T++ + F A+ TGSE + S +G S+T ST+
Sbjct: 258 TEDSETNTAFTE--DSKTTTASTTGFETTAASTTGSEPT--MASTMG--SETTMASTIG- 310
Query: 1011 DHMEQKDLQLDEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLT 1054
P+ ++S SE +V A G+ T
Sbjct: 311 ---------------------PETTKVSTASSEVTTVFAAGSET 333
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,188,169
Number of Sequences: 37866
Number of extensions: 3814759
Number of successful extensions: 12210
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 11820
Number of HSP's gapped (non-prelim): 327
length of query: 2036
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1918
effective length of database: 13,779,330
effective search space: 26428754940
effective search space used: 26428754940
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.