Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 5032179
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5032179 tripartite motif-containing 28 protein [Homo
sapiens]
(835 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5032179 tripartite motif-containing 28 protein [Homo sapiens] 1692 0.0
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 340 3e-93
gi|74027249 tripartite motif-containing 33 protein isoform alpha... 340 3e-93
gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 310 5e-84
gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 310 5e-84
gi|209977097 tripartite motif-containing 66 [Homo sapiens] 166 8e-41
gi|84993742 tripartite motif-containing 71 [Homo sapiens] 108 2e-23
gi|224548923 tripartite motif-containing 45 isoform 2 [Homo sapi... 104 4e-22
gi|224548921 tripartite motif-containing 45 isoform 1 [Homo sapi... 104 4e-22
gi|30794216 tripartite motif-containing 56 [Homo sapiens] 102 1e-21
gi|32454739 tripartite motif-containing 3 [Homo sapiens] 79 2e-14
gi|32454737 tripartite motif-containing 3 [Homo sapiens] 79 2e-14
gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens] 77 5e-14
gi|67089160 promyelocytic leukemia protein isoform 11 [Homo sapi... 76 1e-13
gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens] 76 1e-13
gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens] 76 1e-13
gi|67089154 promyelocytic leukemia protein isoform 8 [Homo sapiens] 76 1e-13
gi|4505903 promyelocytic leukemia protein isoform 6 [Homo sapiens] 76 1e-13
gi|15451775 promyelocytic leukemia protein isoform 7 [Homo sapiens] 76 1e-13
gi|15451779 promyelocytic leukemia protein isoform 10 [Homo sapi... 76 1e-13
gi|67089149 promyelocytic leukemia protein isoform 1 [Homo sapiens] 76 1e-13
gi|109637788 promyelocytic leukemia protein isoform 5 [Homo sapi... 76 1e-13
gi|28195390 tripartite motif-containing 42 [Homo sapiens] 76 1e-13
gi|223890259 midline 2 isoform 2 [Homo sapiens] 76 1e-13
gi|223890257 midline 2 isoform 1 [Homo sapiens] 76 1e-13
gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens] 75 3e-13
gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens] 65 2e-10
gi|124487387 ring finger protein 207 [Homo sapiens] 64 4e-10
gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens] 63 1e-09
gi|134133279 SP140 nuclear body protein-like [Homo sapiens] 63 1e-09
>gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]
Length = 835
Score = 1692 bits (4382), Expect = 0.0
Identities = 835/835 (100%), Positives = 835/835 (100%)
Query: 1 MAASAAAASAAAASAASGSPGPGEGSAGGEKRSTAPSAAASASASAAASSPAGGGAEALE 60
MAASAAAASAAAASAASGSPGPGEGSAGGEKRSTAPSAAASASASAAASSPAGGGAEALE
Sbjct: 1 MAASAAAASAAAASAASGSPGPGEGSAGGEKRSTAPSAAASASASAAASSPAGGGAEALE 60
Query: 61 LLEHCGVCRERLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVC 120
LLEHCGVCRERLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVC
Sbjct: 61 LLEHCGVCRERLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVC 120
Query: 121 KQQCFSKDIVENYFMRDSGSKAATDAQDANQCCTSCEDNAPATSYCVECSEPLCETCVEA 180
KQQCFSKDIVENYFMRDSGSKAATDAQDANQCCTSCEDNAPATSYCVECSEPLCETCVEA
Sbjct: 121 KQQCFSKDIVENYFMRDSGSKAATDAQDANQCCTSCEDNAPATSYCVECSEPLCETCVEA 180
Query: 181 HQRVKYTKDHTVRSTGPAKSRDGERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDH 240
HQRVKYTKDHTVRSTGPAKSRDGERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDH
Sbjct: 181 HQRVKYTKDHTVRSTGPAKSRDGERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDH 240
Query: 241 QYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAIL 300
QYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAIL
Sbjct: 241 QYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAIL 300
Query: 301 QIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWALESDNNTA 360
QIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWALESDNNTA
Sbjct: 301 QIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWALESDNNTA 360
Query: 361 LLLSKKLIYFQLHRALKMIVDPVEPHGEMKFQWDLNAWTKSAEAFGKIVAERPGTNSTGP 420
LLLSKKLIYFQLHRALKMIVDPVEPHGEMKFQWDLNAWTKSAEAFGKIVAERPGTNSTGP
Sbjct: 361 LLLSKKLIYFQLHRALKMIVDPVEPHGEMKFQWDLNAWTKSAEAFGKIVAERPGTNSTGP 420
Query: 421 APMAPPRAPGPLSKQGSGSSQPMEVQEGYGFGSGDDPYSSAEPHVSGVKRSRSGEGEVSG 480
APMAPPRAPGPLSKQGSGSSQPMEVQEGYGFGSGDDPYSSAEPHVSGVKRSRSGEGEVSG
Sbjct: 421 APMAPPRAPGPLSKQGSGSSQPMEVQEGYGFGSGDDPYSSAEPHVSGVKRSRSGEGEVSG 480
Query: 481 LMRKVPRVSLERLDLDLTADSQPPVFKVFPGSTTEDYNLIVIERGAAAAATGQPGTAPAG 540
LMRKVPRVSLERLDLDLTADSQPPVFKVFPGSTTEDYNLIVIERGAAAAATGQPGTAPAG
Sbjct: 481 LMRKVPRVSLERLDLDLTADSQPPVFKVFPGSTTEDYNLIVIERGAAAAATGQPGTAPAG 540
Query: 541 TPGAPPLAGMAIVKEEETEAAIGAPPTATEGPETKPVLMALAEGPGAEGPRLASPSGSTS 600
TPGAPPLAGMAIVKEEETEAAIGAPPTATEGPETKPVLMALAEGPGAEGPRLASPSGSTS
Sbjct: 541 TPGAPPLAGMAIVKEEETEAAIGAPPTATEGPETKPVLMALAEGPGAEGPRLASPSGSTS 600
Query: 601 SGLEVVAPEGTSAPGGGPGTLDDSATICRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVP 660
SGLEVVAPEGTSAPGGGPGTLDDSATICRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVP
Sbjct: 601 SGLEVVAPEGTSAPGGGPGTLDDSATICRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVP 660
Query: 661 GEEWSCSLCHVLPDLKEEDGSLSLDGADSTGVVAKLSPANQRKCERVLLALFCHEPCRPL 720
GEEWSCSLCHVLPDLKEEDGSLSLDGADSTGVVAKLSPANQRKCERVLLALFCHEPCRPL
Sbjct: 661 GEEWSCSLCHVLPDLKEEDGSLSLDGADSTGVVAKLSPANQRKCERVLLALFCHEPCRPL 720
Query: 721 HQLATDSTFSLDQPGGTLDLTLIRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTEDKA 780
HQLATDSTFSLDQPGGTLDLTLIRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTEDKA
Sbjct: 721 HQLATDSTFSLDQPGGTLDLTLIRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTEDKA 780
Query: 781 DVQSIIGLQRFFETRMNEAFGDTKFSAVLVEPPPMSLPGAGLSSQELSGGPGDGP 835
DVQSIIGLQRFFETRMNEAFGDTKFSAVLVEPPPMSLPGAGLSSQELSGGPGDGP
Sbjct: 781 DVQSIIGLQRFFETRMNEAFGDTKFSAVLVEPPPMSLPGAGLSSQELSGGPGDGP 835
>gi|74027251 tripartite motif-containing 33 protein isoform beta
[Homo sapiens]
Length = 1110
Score = 340 bits (872), Expect = 3e-93
Identities = 178/436 (40%), Positives = 266/436 (61%), Gaps = 20/436 (4%)
Query: 5 AAAASAAAASAASGSPGPGEGSAGGEKRSTAPSAAASASASAAASSPAGGGAEALELLEH 64
AAA+S +A +A+S + G G AGG + AP+ A++ + +A P G A LL+
Sbjct: 68 AAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPAS---LLDT 124
Query: 65 CGVCRERL--RPEREPRLLPCLHSACSACLGP-----AAPAAANSSGDGGAAGDGTVVDC 117
C VC++ L R E EP+LLPCLHS C CL + P S+GD G V+ C
Sbjct: 125 CAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDIQQVG---VIRC 181
Query: 118 PVCKQQCFSKDIVENYFMRDSGSKAATDAQDANQCCTSCEDNAPATSYCVECSEPLCETC 177
PVC+Q+C D+V+NYF++D+ ++ + + Q CTSCEDNA A +CVEC E LC+TC
Sbjct: 182 PVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTC 241
Query: 178 VEAHQRVKYTKDHTVRS---TGPAKSRDGERTVYCNVHKHEPLVLFCESCDTLTCRDCQL 234
+EAHQRVK+TKDH +R + G+R V+C VHK E L LFCE+CD LTCRDCQL
Sbjct: 242 IEAHQRVKFTKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQL 301
Query: 235 NAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRVQVD 294
HK+H+YQFLE+A +NQ+ + +L+ +L +K + + +V++ I++V++ KRV+ +
Sbjct: 302 LEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQE 361
Query: 295 VKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWALE 354
+K+AI ++ E+NK+G+ L+ + VT+ +Q +L +Q +T + + +H++ F +WA+
Sbjct: 362 IKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAIA 421
Query: 355 SDNNTALLLSKKLIYFQLHRALKMIVDPVEP-HGEMKFQWDLNAWTKSAEAFGKIVAE-- 411
S ++TALL SK+LI FQL LK DPV +G ++F D W K+ G +V E
Sbjct: 422 SGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIESK 481
Query: 412 -RPGTNSTGPAPMAPP 426
PG PP
Sbjct: 482 PAPGYTPNVVVGQVPP 497
Score = 108 bits (271), Expect = 2e-23
Identities = 66/203 (32%), Positives = 101/203 (49%), Gaps = 11/203 (5%)
Query: 612 SAPGGGPGTLDD---SATICRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSL 668
SA GG G D + C VCQ GDL+ C +C FHL CH+P L P +W C+
Sbjct: 871 SARIGGDGNNKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTF 930
Query: 669 CHVLPDLKEEDGSLSLDGADSTGVVAKLSPANQRKCERVLLALFCHEPC----RPLHQLA 724
C + + E +L + LSP +QRKCER+LL L+CHE P+
Sbjct: 931 CRDIGKPEVEYDCDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASI 990
Query: 725 TDSTFSLDQPGGTLDLTLIRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTEDKADV-Q 783
+ + +P +DL+ ++ +LQ+K S Y P +F DV +FK + E ++V Q
Sbjct: 991 PNYYKIIKKP---MDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEADSEVAQ 1047
Query: 784 SIIGLQRFFETRMNEAFGDTKFS 806
+ + +FE ++ E + D F+
Sbjct: 1048 AGKAVALYFEDKLTEIYSDRTFA 1070
Score = 40.4 bits (93), Expect = 0.007
Identities = 34/116 (29%), Positives = 44/116 (37%), Gaps = 10/116 (8%)
Query: 525 GAAAAATGQPGTAPAGTPGAPPLAGMAIVKEEETEAAIGAPPTATEGPETKPVLMALA-E 583
G+A G G PA PPL + + +EEE GA A GP+ V A +
Sbjct: 18 GSAPVTAGAAG--PAAQEAEPPLTAVLVEEEEEEGGRAGAEGGAA-GPDDGGVAAASSGS 74
Query: 584 GPGAEGPRLASPSGSTSSGLEVVAPEGTSAPGGG------PGTLDDSATICRVCQK 633
A P + +G + AP SAP G PG C VCQ+
Sbjct: 75 AQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQ 130
>gi|74027249 tripartite motif-containing 33 protein isoform alpha
[Homo sapiens]
Length = 1127
Score = 340 bits (872), Expect = 3e-93
Identities = 178/436 (40%), Positives = 266/436 (61%), Gaps = 20/436 (4%)
Query: 5 AAAASAAAASAASGSPGPGEGSAGGEKRSTAPSAAASASASAAASSPAGGGAEALELLEH 64
AAA+S +A +A+S + G G AGG + AP+ A++ + +A P G A LL+
Sbjct: 68 AAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPAS---LLDT 124
Query: 65 CGVCRERL--RPEREPRLLPCLHSACSACLGP-----AAPAAANSSGDGGAAGDGTVVDC 117
C VC++ L R E EP+LLPCLHS C CL + P S+GD G V+ C
Sbjct: 125 CAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDIQQVG---VIRC 181
Query: 118 PVCKQQCFSKDIVENYFMRDSGSKAATDAQDANQCCTSCEDNAPATSYCVECSEPLCETC 177
PVC+Q+C D+V+NYF++D+ ++ + + Q CTSCEDNA A +CVEC E LC+TC
Sbjct: 182 PVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTC 241
Query: 178 VEAHQRVKYTKDHTVRS---TGPAKSRDGERTVYCNVHKHEPLVLFCESCDTLTCRDCQL 234
+EAHQRVK+TKDH +R + G+R V+C VHK E L LFCE+CD LTCRDCQL
Sbjct: 242 IEAHQRVKFTKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQL 301
Query: 235 NAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRVQVD 294
HK+H+YQFLE+A +NQ+ + +L+ +L +K + + +V++ I++V++ KRV+ +
Sbjct: 302 LEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQE 361
Query: 295 VKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWALE 354
+K+AI ++ E+NK+G+ L+ + VT+ +Q +L +Q +T + + +H++ F +WA+
Sbjct: 362 IKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAIA 421
Query: 355 SDNNTALLLSKKLIYFQLHRALKMIVDPVEP-HGEMKFQWDLNAWTKSAEAFGKIVAE-- 411
S ++TALL SK+LI FQL LK DPV +G ++F D W K+ G +V E
Sbjct: 422 SGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIESK 481
Query: 412 -RPGTNSTGPAPMAPP 426
PG PP
Sbjct: 482 PAPGYTPNVVVGQVPP 497
Score = 103 bits (256), Expect = 9e-22
Identities = 70/220 (31%), Positives = 104/220 (47%), Gaps = 28/220 (12%)
Query: 612 SAPGGGPGTLDD---SATICRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSL 668
SA GG G D + C VCQ GDL+ C +C FHL CH+P L P +W C+
Sbjct: 871 SARIGGDGNNKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTF 930
Query: 669 CHVLPDLKEEDGSLSLDGADSTGVVAKLSPANQRKCERVLLALFCHEPC----RPLHQLA 724
C + + E +L + LSP +QRKCER+LL L+CHE P+
Sbjct: 931 CRDIGKPEVEYDCDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASI 990
Query: 725 TDSTFSLDQPGGTLDLTLIRARLQEKLSPPYSSPQEFAQDVGRMFK---QFN---KLTED 778
+ + +P +DL+ ++ +LQ+K S Y P +F DV +FK +FN K+ +
Sbjct: 991 PNYYKIIKKP---MDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMKVVQV 1047
Query: 779 KADVQSI------------IGLQRFFETRMNEAFGDTKFS 806
AD Q I + +FE ++ E + D F+
Sbjct: 1048 YADTQEINLKADSEVAQAGKAVALYFEDKLTEIYSDRTFA 1087
Score = 40.4 bits (93), Expect = 0.007
Identities = 34/116 (29%), Positives = 44/116 (37%), Gaps = 10/116 (8%)
Query: 525 GAAAAATGQPGTAPAGTPGAPPLAGMAIVKEEETEAAIGAPPTATEGPETKPVLMALA-E 583
G+A G G PA PPL + + +EEE GA A GP+ V A +
Sbjct: 18 GSAPVTAGAAG--PAAQEAEPPLTAVLVEEEEEEGGRAGAEGGAA-GPDDGGVAAASSGS 74
Query: 584 GPGAEGPRLASPSGSTSSGLEVVAPEGTSAPGGG------PGTLDDSATICRVCQK 633
A P + +G + AP SAP G PG C VCQ+
Sbjct: 75 AQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQ 130
>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
[Homo sapiens]
Length = 1050
Score = 310 bits (793), Expect = 5e-84
Identities = 165/433 (38%), Positives = 253/433 (58%), Gaps = 40/433 (9%)
Query: 5 AAAASAAAASAASGSPGPGEGSAGGEKRSTAPSAAASASASAAASSPAGGGAEALELLEH 64
A AA+AAA++AASG P S APS A + S GG A L LL+
Sbjct: 8 AVAAAAAASAAASGGP------------SAAPSGENEAESRQGPDSERGGEAARLNLLDT 55
Query: 65 CGVCRERLRPEREPRLLPCLHSACSACLG-------------------PAAPAAANS-SG 104
C VC + ++ R P+LLPCLHS C CL P PA + SG
Sbjct: 56 CAVCHQNIQ-SRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSG 114
Query: 105 DGGAAGDGTVVDCPVCKQQCFSKDIVENYFMRDSGSKAATDAQDANQCCTSCEDNAPATS 164
A V+ CPVC Q+C + I++N+F++D+ ++ + +NQ CTSCEDNA A
Sbjct: 115 SSPFATQVGVIRCPVCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANG 174
Query: 165 YCVECSEPLCETCVEAHQRVKYTKDHTVRS----TGPAKSRDGERTVYCNVHKHEPLVLF 220
+CVEC E LC+TC+ AHQRVK+TKDHTVR + A +R V+C HK E L L+
Sbjct: 175 FCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLY 234
Query: 221 CESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSS 280
CE+CD LTCRDCQL HK+H+YQF+E+A +NQ+ ++ +L+ +L +K ++ + ++++
Sbjct: 235 CETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNR 294
Query: 281 IRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQK 340
I +V+ QK+V+ D+K+AI +M E+NK+G+ L++ + + + + +L +Q + + K
Sbjct: 295 IIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSK 354
Query: 341 HQEHILRFASWALESDNNTALLLSKKLIYFQLHRALKMIVD--PVEPHGEMKFQWDLNAW 398
EH++ F+ WA+ S ++TALL SK+LI ++L L+ D PV + ++F D + W
Sbjct: 355 QLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPV-TNNTIQFHCDPSFW 413
Query: 399 TKSAEAFGKIVAE 411
++ G +V E
Sbjct: 414 AQNIINLGSLVIE 426
Score = 104 bits (259), Expect = 4e-22
Identities = 64/194 (32%), Positives = 98/194 (50%), Gaps = 16/194 (8%)
Query: 622 DDSATICRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSLCHVL--PDLKEE- 678
D + C VCQ G+L+ C +C FHL CH+P L + P EW C+ C L P+++ +
Sbjct: 823 DPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDC 882
Query: 679 DGSLSLDGADSTGVVAKLSPANQRKCERVLLALFCHEPCRPLHQLATDSTFSLDQPG--- 735
D T + KL+P ++RKCER+LL L+CHE LA L P
Sbjct: 883 DAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHE-----MSLAFQDPVPLTVPDYYK 937
Query: 736 ---GTLDLTLIRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTEDKADVQSI-IGLQRF 791
+DL+ I+ RLQE S YS P++F D +F+ + E ++V + I L+ +
Sbjct: 938 IIKNPMDLSTIKKRLQEDYS-MYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENY 996
Query: 792 FETRMNEAFGDTKF 805
FE + + + +F
Sbjct: 997 FEELLKNLYPEKRF 1010
>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
[Homo sapiens]
Length = 1016
Score = 310 bits (793), Expect = 5e-84
Identities = 165/433 (38%), Positives = 253/433 (58%), Gaps = 40/433 (9%)
Query: 5 AAAASAAAASAASGSPGPGEGSAGGEKRSTAPSAAASASASAAASSPAGGGAEALELLEH 64
A AA+AAA++AASG P S APS A + S GG A L LL+
Sbjct: 8 AVAAAAAASAAASGGP------------SAAPSGENEAESRQGPDSERGGEAARLNLLDT 55
Query: 65 CGVCRERLRPEREPRLLPCLHSACSACLG-------------------PAAPAAANS-SG 104
C VC + ++ R P+LLPCLHS C CL P PA + SG
Sbjct: 56 CAVCHQNIQ-SRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSG 114
Query: 105 DGGAAGDGTVVDCPVCKQQCFSKDIVENYFMRDSGSKAATDAQDANQCCTSCEDNAPATS 164
A V+ CPVC Q+C + I++N+F++D+ ++ + +NQ CTSCEDNA A
Sbjct: 115 SSPFATQVGVIRCPVCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANG 174
Query: 165 YCVECSEPLCETCVEAHQRVKYTKDHTVRS----TGPAKSRDGERTVYCNVHKHEPLVLF 220
+CVEC E LC+TC+ AHQRVK+TKDHTVR + A +R V+C HK E L L+
Sbjct: 175 FCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLY 234
Query: 221 CESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSS 280
CE+CD LTCRDCQL HK+H+YQF+E+A +NQ+ ++ +L+ +L +K ++ + ++++
Sbjct: 235 CETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNR 294
Query: 281 IRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQK 340
I +V+ QK+V+ D+K+AI +M E+NK+G+ L++ + + + + +L +Q + + K
Sbjct: 295 IIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSK 354
Query: 341 HQEHILRFASWALESDNNTALLLSKKLIYFQLHRALKMIVD--PVEPHGEMKFQWDLNAW 398
EH++ F+ WA+ S ++TALL SK+LI ++L L+ D PV + ++F D + W
Sbjct: 355 QLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPV-TNNTIQFHCDPSFW 413
Query: 399 TKSAEAFGKIVAE 411
++ G +V E
Sbjct: 414 AQNIINLGSLVIE 426
Score = 104 bits (259), Expect = 4e-22
Identities = 64/194 (32%), Positives = 98/194 (50%), Gaps = 16/194 (8%)
Query: 622 DDSATICRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSLCHVL--PDLKEE- 678
D + C VCQ G+L+ C +C FHL CH+P L + P EW C+ C L P+++ +
Sbjct: 789 DPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDC 848
Query: 679 DGSLSLDGADSTGVVAKLSPANQRKCERVLLALFCHEPCRPLHQLATDSTFSLDQPG--- 735
D T + KL+P ++RKCER+LL L+CHE LA L P
Sbjct: 849 DAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHE-----MSLAFQDPVPLTVPDYYK 903
Query: 736 ---GTLDLTLIRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTEDKADVQSI-IGLQRF 791
+DL+ I+ RLQE S YS P++F D +F+ + E ++V + I L+ +
Sbjct: 904 IIKNPMDLSTIKKRLQEDYS-MYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENY 962
Query: 792 FETRMNEAFGDTKF 805
FE + + + +F
Sbjct: 963 FEELLKNLYPEKRF 976
>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
Length = 1216
Score = 166 bits (420), Expect = 8e-41
Identities = 92/283 (32%), Positives = 149/283 (52%), Gaps = 22/283 (7%)
Query: 153 CTSCEDNAPATSYCVECSEPLCETCVEAHQRVKYTKDHTVRSTGPAKSR----------- 201
C+ C++ A C C+ LC +C E H+ H+ GP R
Sbjct: 5 CSECKEKRAAHILCTYCNRWLCSSCTEEHR-------HSPVPGGPFFPRAQKGSPGVNGG 57
Query: 202 DGERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVK 261
G+ T+YC +H E L LFCE+CD LTC C + HK+H+ + +E+ ++NQR LL +
Sbjct: 58 PGDFTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTT 117
Query: 262 RLGDKHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVT 321
++ K ++LQ S K++ I +V ++V+ +KMA + +M ELNK+ L+ + + +T
Sbjct: 118 QVAHKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGIT 177
Query: 322 EGQQERLERQHWTMTKIQKHQEHILRFASWALESDNNTALLLSKKLIYFQLHRALKMI-- 379
++ +LE+Q ++ + + EH+ F +WA+ S + L SK+LI FQ+ R L+
Sbjct: 178 NERKRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCN 237
Query: 380 VDPVEPHGEMKFQWDLNAWTKSAEAFGKIVAERPGTNSTGPAP 422
DP P ++F W+ N WTK + G I E G S AP
Sbjct: 238 TDPGSP-WSIRFTWEPNFWTKQLASLGCITTE-GGQMSRADAP 278
Score = 118 bits (295), Expect = 3e-26
Identities = 97/332 (29%), Positives = 155/332 (46%), Gaps = 44/332 (13%)
Query: 484 KVPRVSLERLDLDLTADSQPPVFKVFPGSTTEDYN-LIVIERGAAAAATGQPGTAPAGTP 542
K+P V LERL + + + PVFK+ P +D + L++IE G +++
Sbjct: 858 KIPYVRLERLKICAASSGEMPVFKLKPQKNDQDGSFLLIIECGTESSS------------ 905
Query: 543 GAPPLAGMAI-VKEEETEAAIGAPPTATEGPETKPVLMALAEGPGAEGPRLASPSGSTSS 601
M+I V ++ A AP EG + +A P EG TS
Sbjct: 906 -------MSIKVSQDRLSEATQAP--GLEGRKVTVTSLAGQRPPEVEG---------TSP 947
Query: 602 GLEVVAPEGTSAPGGGPGTLDDSATICRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPG 661
+ P A G P +++ C VC G+L+ C++C FHL CH+PAL PG
Sbjct: 948 EEHRLIPRTPGAKKGPPAPIENE-DFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPG 1006
Query: 662 EEWSCSLCHVL--PDLKEEDGSLSLDGADSTGVVAKLSPANQRKCERVLLALFCHEPCRP 719
EW C+LC L P++ E D + LS +Q+KCE+++L+L C+ P
Sbjct: 1007 GEWVCTLCRSLTQPEM-EYDCENACYNQPGMRASPGLSMYDQKKCEKLVLSLCCNNLSLP 1065
Query: 720 LHQ----LATDSTFSLDQPGGTLDLTLIRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKL 775
H+ LA + +P +DL++IR +LQ+K Y++P+E DV MF K
Sbjct: 1066 FHEPVSPLARHYYQIIKRP---MDLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKF 1122
Query: 776 TEDKADV-QSIIGLQRFFETRMNEAFGDTKFS 806
++V ++ L+ FFE + E + + +F+
Sbjct: 1123 NYPDSEVAEAGRCLEVFFEGWLKEIYPEKRFA 1154
>gi|84993742 tripartite motif-containing 71 [Homo sapiens]
Length = 868
Score = 108 bits (270), Expect = 2e-23
Identities = 100/427 (23%), Positives = 168/427 (39%), Gaps = 46/427 (10%)
Query: 4 SAAAASAAAASAASGSPGPGEGSAGGEKRSTAPSAAASASASAAASSPAGGGAEALELLE 63
S+A++S++ S +SG G G G+A A A PA GG A E L+
Sbjct: 29 SSASSSSSQTSTSSGGGGGGPGAAARRLHVLPCLHAFCRPCLEAHRLPAAGGGAAGEPLK 88
Query: 64 -HCGVCRERL---------RPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGT 113
C VC +++ LL L A A P + GA G
Sbjct: 89 LRCPVCDQKVVLAEAAGMDALPSSAFLLSNLLDAVVATADEPPPKNGRAGAPAGAGGHSN 148
Query: 114 VVDCP--VCKQQCFSKDIVENYFMRDSGSKAATDAQDANQC---------CTSCEDNAPA 162
+ S + + S++A A+ C+SC++ A
Sbjct: 149 HRHHAHHAHPRASASAPPLPQAPQPPAPSRSAPGGPAASPSALLLRRPHGCSSCDEGNAA 208
Query: 163 TSYCVECSEPLCETCVEAHQRVKYTKDHTVRSTGPAKSRDG------------------- 203
+S C++C E LC+ CV AHQRV+ TKDH + P
Sbjct: 209 SSRCLDCQEHLCDNCVRAHQRVRLTKDHYIERGPPGPGAAAAAQQLGLGPPFPGPPFSIL 268
Query: 204 ----ERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASL 259
ER +C H E L L+C++C CR+C + H H + +L++A+++ R L L
Sbjct: 269 SVFPERLGFCQHHDDEVLHLYCDTCSVPICRECTMGRHGGHSFIYLQEALQDSRALTIQL 328
Query: 260 VKRLGDKHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQK 319
+ +Q S ++ ++ QV K VQ +VK + K L +R L+ +K
Sbjct: 329 LADAQQGRQAIQLSIEQAQTVAEQVEMKAKVVQSEVKAVTARHKKALEERECELLWKVEK 388
Query: 320 VTEGQQERLERQHWTMTKIQKHQEHILRFASWALESDNNTALLLSKKLIYFQLH--RALK 377
+ + + + L Q + + E + LE +LL++ + Q+ + ++
Sbjct: 389 IRQVKAKSLYLQVEKLRQNLNKLESTISAVQQVLEEGRALDILLARDRMLAQVQELKTVR 448
Query: 378 MIVDPVE 384
++ P E
Sbjct: 449 SLLQPQE 455
Score = 48.5 bits (114), Expect = 3e-05
Identities = 36/106 (33%), Positives = 48/106 (45%), Gaps = 28/106 (26%)
Query: 18 GSPGPGEGSAGGEKRSTAPSAAASASASAAASSPAGGGAEALELLEHCGVCRERLRPERE 77
GSP P ++ S+A+S+S+ + SS GGG G RL
Sbjct: 20 GSPAP----------LSSNSSASSSSSQTSTSSGGGGGGP--------GAAARRLH---- 57
Query: 78 PRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQ 123
+LPCLH+ C CL AA GGAAG+ + CPVC Q+
Sbjct: 58 --VLPCLHAFCRPCLEAHRLPAAG----GGAAGEPLKLRCPVCDQK 97
>gi|224548923 tripartite motif-containing 45 isoform 2 [Homo
sapiens]
Length = 562
Score = 104 bits (259), Expect = 4e-22
Identities = 78/338 (23%), Positives = 138/338 (40%), Gaps = 28/338 (8%)
Query: 64 HCGVCRERLRPEREPRLLPCLHSACSACLGPAAPAAANS--SGDGGAAGDGTVVD----- 116
HC +C L + PRLLPCLH+ C+ CL P + GD + +G++
Sbjct: 28 HCPLC---LGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPR 84
Query: 117 ---------CPVCKQQCFS-----KDIVENYFMRDSGSKAATDAQDANQCCTSCEDNAPA 162
CPVC Q K + ++ + + + C C D
Sbjct: 85 SLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEGQGLVCDLCNDRE-V 143
Query: 163 TSYCVECSEPLCETCVEAHQRVKYTKDHTVRSTGPAK--SRDGERTVYCNVHKHEPLVLF 220
C C LC C +AH+R K T HT+ K SR G + + C VH E L LF
Sbjct: 144 EKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIG-KPILCPVHPAEELRLF 202
Query: 221 CESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSS 280
CE CD C+DC + H++H F + + + L+K L+++ ++
Sbjct: 203 CEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHII 262
Query: 281 IRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQK 340
+ + V DV+ +K + + L+ + + ++ L+ Q + ++
Sbjct: 263 NSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLA 322
Query: 341 HQEHILRFASWALESDNNTALLLSKKLIYFQLHRALKM 378
+ F L S ++ +L++K+++ +L + K+
Sbjct: 323 DMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKV 360
>gi|224548921 tripartite motif-containing 45 isoform 1 [Homo
sapiens]
Length = 580
Score = 104 bits (259), Expect = 4e-22
Identities = 78/338 (23%), Positives = 138/338 (40%), Gaps = 28/338 (8%)
Query: 64 HCGVCRERLRPEREPRLLPCLHSACSACLGPAAPAAANS--SGDGGAAGDGTVVD----- 116
HC +C L + PRLLPCLH+ C+ CL P + GD + +G++
Sbjct: 28 HCPLC---LGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPR 84
Query: 117 ---------CPVCKQQCFS-----KDIVENYFMRDSGSKAATDAQDANQCCTSCEDNAPA 162
CPVC Q K + ++ + + + C C D
Sbjct: 85 SLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEGQGLVCDLCNDRE-V 143
Query: 163 TSYCVECSEPLCETCVEAHQRVKYTKDHTVRSTGPAK--SRDGERTVYCNVHKHEPLVLF 220
C C LC C +AH+R K T HT+ K SR G + + C VH E L LF
Sbjct: 144 EKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIG-KPILCPVHPAEELRLF 202
Query: 221 CESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSS 280
CE CD C+DC + H++H F + + + L+K L+++ ++
Sbjct: 203 CEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHII 262
Query: 281 IRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQK 340
+ + V DV+ +K + + L+ + + ++ L+ Q + ++
Sbjct: 263 NSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLA 322
Query: 341 HQEHILRFASWALESDNNTALLLSKKLIYFQLHRALKM 378
+ F L S ++ +L++K+++ +L + K+
Sbjct: 323 DMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKV 360
>gi|30794216 tripartite motif-containing 56 [Homo sapiens]
Length = 755
Score = 102 bits (255), Expect = 1e-21
Identities = 69/283 (24%), Positives = 120/283 (42%), Gaps = 38/283 (13%)
Query: 65 CGVCRERLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQC 124
C +C E+LR P+ LPCLH+ C CL A DG V CP C++
Sbjct: 21 CKICLEQLRA---PKTLPCLHTYCQDCLAQLA--------------DGGRVRCPECRETV 63
Query: 125 ---------FSKDIVENYFMRDSGSKAATDAQDANQCCTSC------EDNAPATSYCVEC 169
F + N + ++A D + C C PAT+ C++C
Sbjct: 64 PVPPEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATARCLDC 123
Query: 170 SEPLCETCVEAHQRVKYTKDHTV------RSTGPAKSRDGERTVYCNVHKHEPLVLFCES 223
++ LC+ C + H+ + T H V R+ + + C H E L C+
Sbjct: 124 ADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQP 183
Query: 224 CDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQ 283
C L CR+C+L+ H DH L +AVR +R L L+ + + L+ + + + ++ +
Sbjct: 184 CSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEALAR 243
Query: 284 VSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQE 326
+ + RV V+ A +++ L + + ++ + E +E
Sbjct: 244 LREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEE 286
>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
Length = 744
Score = 79.0 bits (193), Expect = 2e-14
Identities = 73/326 (22%), Positives = 125/326 (38%), Gaps = 60/326 (18%)
Query: 65 CGVCRERLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQC 124
C +C +R + P++LPCLH+ C CL PA + CPVC+Q
Sbjct: 22 CSICLDRYQC---PKVLPCLHTFCERCLQNYIPA------------QSLTLSCPVCRQTS 66
Query: 125 FSKD----IVENYFMRDSGSKAATDAQDANQCCTSCEDNAPATSYCVECSEPLCETCVEA 180
+ ++N F S +A A D ED P + V PL
Sbjct: 67 ILPEQGVSALQNNFFISSLMEAMQQAPDG---AHDPEDPHPLS---VVAGRPLS------ 114
Query: 181 HQRVKYTKDHTVRSTGPAKSRDGERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDH 240
C H+ + + +CE+C+T C +C+ H++H
Sbjct: 115 ----------------------------CPNHEGKTMEFYCEACETAMCGECRAGEHREH 146
Query: 241 QYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAIL 300
L D V + L ++ + + L + V +Q+ + + + A
Sbjct: 147 GTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFE 206
Query: 301 QIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWALESDNNTA 360
+ + L +R + LV+D + + +Q+ L+ Q T+ + Q+H FA AL +
Sbjct: 207 DLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFAEQALRLGSAPE 266
Query: 361 LLLSKKLIYFQLHRALKMIVDPVEPH 386
+LL +K + +L AL P PH
Sbjct: 267 VLLVRKHMRERL-AALAAQAFPERPH 291
>gi|32454737 tripartite motif-containing 3 [Homo sapiens]
Length = 744
Score = 79.0 bits (193), Expect = 2e-14
Identities = 73/326 (22%), Positives = 125/326 (38%), Gaps = 60/326 (18%)
Query: 65 CGVCRERLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQC 124
C +C +R + P++LPCLH+ C CL PA + CPVC+Q
Sbjct: 22 CSICLDRYQC---PKVLPCLHTFCERCLQNYIPA------------QSLTLSCPVCRQTS 66
Query: 125 FSKD----IVENYFMRDSGSKAATDAQDANQCCTSCEDNAPATSYCVECSEPLCETCVEA 180
+ ++N F S +A A D ED P + V PL
Sbjct: 67 ILPEQGVSALQNNFFISSLMEAMQQAPDG---AHDPEDPHPLS---VVAGRPLS------ 114
Query: 181 HQRVKYTKDHTVRSTGPAKSRDGERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDH 240
C H+ + + +CE+C+T C +C+ H++H
Sbjct: 115 ----------------------------CPNHEGKTMEFYCEACETAMCGECRAGEHREH 146
Query: 241 QYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAIL 300
L D V + L ++ + + L + V +Q+ + + + A
Sbjct: 147 GTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFE 206
Query: 301 QIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWALESDNNTA 360
+ + L +R + LV+D + + +Q+ L+ Q T+ + Q+H FA AL +
Sbjct: 207 DLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFAEQALRLGSAPE 266
Query: 361 LLLSKKLIYFQLHRALKMIVDPVEPH 386
+LL +K + +L AL P PH
Sbjct: 267 VLLVRKHMRERL-AALAAQAFPERPH 291
>gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]
Length = 771
Score = 77.4 bits (189), Expect = 5e-14
Identities = 85/412 (20%), Positives = 152/412 (36%), Gaps = 70/412 (16%)
Query: 17 SGSPGPGEGSAGGEKRSTAPSAAASASASAAASSPAGGGAEALELLEHCGVCRERLRPER 76
SG G + AG ++ P S AS + P+ + + C +C ER +
Sbjct: 4 SGRYGTQQQRAGS--KTAGPPCQWSRMASEGTNIPSPVVRQIDKQFLICSICLERYK--- 58
Query: 77 EPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQCFSKD-----IVE 131
P++LPCLH+ C CL PA + + CPVC+Q + +
Sbjct: 59 NPKVLPCLHTFCERCLQNYIPAHS------------LTLSCPVCRQTSILPEKGVAALQN 106
Query: 132 NYFMRDSGSKAATDAQDANQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVKYTKDHT 191
N+F+ + D + E + T V +PL
Sbjct: 107 NFFITN-----LMDVLQRTPGSNAEESSILETVTAVAAGKPLS----------------- 144
Query: 192 VRSTGPAKSRDGERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRN 251
C H + +C+SC+T CR+C H +H L+D V
Sbjct: 145 -----------------CPNHDGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQ 187
Query: 252 QRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGR 311
+ L + + + + + + + I Q+++ + + D+ ++ K LN R
Sbjct: 188 HKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKS 247
Query: 312 VLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWALESDNNTALLLSKKLIYFQ 371
VL+ + + + + L+ Q T+ + Q+ + F + AL T +LL KK Q
Sbjct: 248 VLLMELEVNYGLKHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKK----Q 303
Query: 372 LHRALKMIVD---PVEP--HGEMKFQWDLNAWTKSAEAFGKIVAERPGTNST 418
+ L + D P+ P + ++ F + KS G I+ + T
Sbjct: 304 MSEKLNELADQDFPLHPRENDQLDFIVETEGLKKSIHNLGTILTTNAVASET 355
>gi|67089160 promyelocytic leukemia protein isoform 11 [Homo
sapiens]
Length = 781
Score = 76.3 bits (186), Expect = 1e-13
Identities = 78/369 (21%), Positives = 149/369 (40%), Gaps = 55/369 (14%)
Query: 15 AASGSPGPGEGSAGGEKRST----APSAAASASASAAASSPAGGGAEALELLEHCGVCRE 70
A + SP P + A ++ + PS S S + + A E + L C++
Sbjct: 4 APARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLR----CQQ 59
Query: 71 RLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQC---FSK 127
+ P+LLPCLH+ CS CL + + + CP+C+
Sbjct: 60 CQAEAKCPKLLPCLHTLCSGCL------------------EASGMQCPICQAPWPLGADT 101
Query: 128 DIVENYFMRDSGSKAATDAQ--DANQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVK 185
++N F + + Q DA CT C+++ A +C EC + LC C EAHQ
Sbjct: 102 PALDNVFFESLQRRLSVYRQIVDAQAVCTRCKES--ADFWCFECEQLLCAKCFEAHQ--- 156
Query: 186 YTKDHTVRSTGPAKSR------DGER---TVYCNVHKHEPLVL---FCESCDTLTCRDCQ 233
+ H R +++ DG R ++C+ H L +C C C C
Sbjct: 157 WFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCA 216
Query: 234 L--NAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRV 291
L ++H + + + + Q +L A + + L ++ + ++ +++ Q+ +
Sbjct: 217 LLDSSHSELKCDISAEIQQRQEELDA-MTQALQEQDSAFGAVHAQMHAAVGQLGRARAET 275
Query: 292 QVDVKMAILQIMKELNKRGRVLVN--DA--QKVTEGQQERLERQHWTMTKIQKHQEHILR 347
+ ++ + Q++ + + R L+ DA Q+ E RL R + +I+ + R
Sbjct: 276 EELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQR 335
Query: 348 FASWALESD 356
+A + +
Sbjct: 336 MKCYASDQE 344
>gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens]
Length = 611
Score = 76.3 bits (186), Expect = 1e-13
Identities = 78/369 (21%), Positives = 149/369 (40%), Gaps = 55/369 (14%)
Query: 15 AASGSPGPGEGSAGGEKRST----APSAAASASASAAASSPAGGGAEALELLEHCGVCRE 70
A + SP P + A ++ + PS S S + + A E + L C++
Sbjct: 4 APARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLR----CQQ 59
Query: 71 RLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQC---FSK 127
+ P+LLPCLH+ CS CL + + + CP+C+
Sbjct: 60 CQAEAKCPKLLPCLHTLCSGCL------------------EASGMQCPICQAPWPLGADT 101
Query: 128 DIVENYFMRDSGSKAATDAQ--DANQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVK 185
++N F + + Q DA CT C+++ A +C EC + LC C EAHQ
Sbjct: 102 PALDNVFFESLQRRLSVYRQIVDAQAVCTRCKES--ADFWCFECEQLLCAKCFEAHQ--- 156
Query: 186 YTKDHTVRSTGPAKSR------DGER---TVYCNVHKHEPLVL---FCESCDTLTCRDCQ 233
+ H R +++ DG R ++C+ H L +C C C C
Sbjct: 157 WFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCA 216
Query: 234 L--NAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRV 291
L ++H + + + + Q +L A + + L ++ + ++ +++ Q+ +
Sbjct: 217 LLDSSHSELKCDISAEIQQRQEELDA-MTQALQEQDSAFGAVHAQMHAAVGQLGRARAET 275
Query: 292 QVDVKMAILQIMKELNKRGRVLVN--DA--QKVTEGQQERLERQHWTMTKIQKHQEHILR 347
+ ++ + Q++ + + R L+ DA Q+ E RL R + +I+ + R
Sbjct: 276 EELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQR 335
Query: 348 FASWALESD 356
+A + +
Sbjct: 336 MKCYASDQE 344
>gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens]
Length = 829
Score = 76.3 bits (186), Expect = 1e-13
Identities = 78/369 (21%), Positives = 149/369 (40%), Gaps = 55/369 (14%)
Query: 15 AASGSPGPGEGSAGGEKRST----APSAAASASASAAASSPAGGGAEALELLEHCGVCRE 70
A + SP P + A ++ + PS S S + + A E + L C++
Sbjct: 4 APARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLR----CQQ 59
Query: 71 RLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQC---FSK 127
+ P+LLPCLH+ CS CL + + + CP+C+
Sbjct: 60 CQAEAKCPKLLPCLHTLCSGCL------------------EASGMQCPICQAPWPLGADT 101
Query: 128 DIVENYFMRDSGSKAATDAQ--DANQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVK 185
++N F + + Q DA CT C+++ A +C EC + LC C EAHQ
Sbjct: 102 PALDNVFFESLQRRLSVYRQIVDAQAVCTRCKES--ADFWCFECEQLLCAKCFEAHQ--- 156
Query: 186 YTKDHTVRSTGPAKSR------DGER---TVYCNVHKHEPLVL---FCESCDTLTCRDCQ 233
+ H R +++ DG R ++C+ H L +C C C C
Sbjct: 157 WFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCA 216
Query: 234 L--NAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRV 291
L ++H + + + + Q +L A + + L ++ + ++ +++ Q+ +
Sbjct: 217 LLDSSHSELKCDISAEIQQRQEELDA-MTQALQEQDSAFGAVHAQMHAAVGQLGRARAET 275
Query: 292 QVDVKMAILQIMKELNKRGRVLVN--DA--QKVTEGQQERLERQHWTMTKIQKHQEHILR 347
+ ++ + Q++ + + R L+ DA Q+ E RL R + +I+ + R
Sbjct: 276 EELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQR 335
Query: 348 FASWALESD 356
+A + +
Sbjct: 336 MKCYASDQE 344
>gi|67089154 promyelocytic leukemia protein isoform 8 [Homo sapiens]
Length = 435
Score = 76.3 bits (186), Expect = 1e-13
Identities = 78/369 (21%), Positives = 149/369 (40%), Gaps = 55/369 (14%)
Query: 15 AASGSPGPGEGSAGGEKRST----APSAAASASASAAASSPAGGGAEALELLEHCGVCRE 70
A + SP P + A ++ + PS S S + + A E + L C++
Sbjct: 4 APARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLR----CQQ 59
Query: 71 RLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQC---FSK 127
+ P+LLPCLH+ CS CL + + + CP+C+
Sbjct: 60 CQAEAKCPKLLPCLHTLCSGCL------------------EASGMQCPICQAPWPLGADT 101
Query: 128 DIVENYFMRDSGSKAATDAQ--DANQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVK 185
++N F + + Q DA CT C+++ A +C EC + LC C EAHQ
Sbjct: 102 PALDNVFFESLQRRLSVYRQIVDAQAVCTRCKES--ADFWCFECEQLLCAKCFEAHQ--- 156
Query: 186 YTKDHTVRSTGPAKSR------DGER---TVYCNVHKHEPLVL---FCESCDTLTCRDCQ 233
+ H R +++ DG R ++C+ H L +C C C C
Sbjct: 157 WFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCA 216
Query: 234 L--NAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRV 291
L ++H + + + + Q +L A + + L ++ + ++ +++ Q+ +
Sbjct: 217 LLDSSHSELKCDISAEIQQRQEELDA-MTQALQEQDSAFGAVHAQMHAAVGQLGRARAET 275
Query: 292 QVDVKMAILQIMKELNKRGRVLVN--DA--QKVTEGQQERLERQHWTMTKIQKHQEHILR 347
+ ++ + Q++ + + R L+ DA Q+ E RL R + +I+ + R
Sbjct: 276 EELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQR 335
Query: 348 FASWALESD 356
+A + +
Sbjct: 336 MKCYASDQE 344
>gi|4505903 promyelocytic leukemia protein isoform 6 [Homo sapiens]
Length = 633
Score = 76.3 bits (186), Expect = 1e-13
Identities = 78/369 (21%), Positives = 149/369 (40%), Gaps = 55/369 (14%)
Query: 15 AASGSPGPGEGSAGGEKRST----APSAAASASASAAASSPAGGGAEALELLEHCGVCRE 70
A + SP P + A ++ + PS S S + + A E + L C++
Sbjct: 4 APARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLR----CQQ 59
Query: 71 RLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQC---FSK 127
+ P+LLPCLH+ CS CL + + + CP+C+
Sbjct: 60 CQAEAKCPKLLPCLHTLCSGCL------------------EASGMQCPICQAPWPLGADT 101
Query: 128 DIVENYFMRDSGSKAATDAQ--DANQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVK 185
++N F + + Q DA CT C+++ A +C EC + LC C EAHQ
Sbjct: 102 PALDNVFFESLQRRLSVYRQIVDAQAVCTRCKES--ADFWCFECEQLLCAKCFEAHQ--- 156
Query: 186 YTKDHTVRSTGPAKSR------DGER---TVYCNVHKHEPLVL---FCESCDTLTCRDCQ 233
+ H R +++ DG R ++C+ H L +C C C C
Sbjct: 157 WFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCA 216
Query: 234 L--NAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRV 291
L ++H + + + + Q +L A + + L ++ + ++ +++ Q+ +
Sbjct: 217 LLDSSHSELKCDISAEIQQRQEELDA-MTQALQEQDSAFGAVHAQMHAAVGQLGRARAET 275
Query: 292 QVDVKMAILQIMKELNKRGRVLVN--DA--QKVTEGQQERLERQHWTMTKIQKHQEHILR 347
+ ++ + Q++ + + R L+ DA Q+ E RL R + +I+ + R
Sbjct: 276 EELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQR 335
Query: 348 FASWALESD 356
+A + +
Sbjct: 336 MKCYASDQE 344
>gi|15451775 promyelocytic leukemia protein isoform 7 [Homo sapiens]
Length = 423
Score = 76.3 bits (186), Expect = 1e-13
Identities = 78/369 (21%), Positives = 149/369 (40%), Gaps = 55/369 (14%)
Query: 15 AASGSPGPGEGSAGGEKRST----APSAAASASASAAASSPAGGGAEALELLEHCGVCRE 70
A + SP P + A ++ + PS S S + + A E + L C++
Sbjct: 4 APARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLR----CQQ 59
Query: 71 RLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQC---FSK 127
+ P+LLPCLH+ CS CL + + + CP+C+
Sbjct: 60 CQAEAKCPKLLPCLHTLCSGCL------------------EASGMQCPICQAPWPLGADT 101
Query: 128 DIVENYFMRDSGSKAATDAQ--DANQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVK 185
++N F + + Q DA CT C+++ A +C EC + LC C EAHQ
Sbjct: 102 PALDNVFFESLQRRLSVYRQIVDAQAVCTRCKES--ADFWCFECEQLLCAKCFEAHQ--- 156
Query: 186 YTKDHTVRSTGPAKSR------DGER---TVYCNVHKHEPLVL---FCESCDTLTCRDCQ 233
+ H R +++ DG R ++C+ H L +C C C C
Sbjct: 157 WFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCA 216
Query: 234 L--NAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRV 291
L ++H + + + + Q +L A + + L ++ + ++ +++ Q+ +
Sbjct: 217 LLDSSHSELKCDISAEIQQRQEELDA-MTQALQEQDSAFGAVHAQMHAAVGQLGRARAET 275
Query: 292 QVDVKMAILQIMKELNKRGRVLVN--DA--QKVTEGQQERLERQHWTMTKIQKHQEHILR 347
+ ++ + Q++ + + R L+ DA Q+ E RL R + +I+ + R
Sbjct: 276 EELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQR 335
Query: 348 FASWALESD 356
+A + +
Sbjct: 336 MKCYASDQE 344
>gi|15451779 promyelocytic leukemia protein isoform 10 [Homo
sapiens]
Length = 585
Score = 76.3 bits (186), Expect = 1e-13
Identities = 78/369 (21%), Positives = 149/369 (40%), Gaps = 55/369 (14%)
Query: 15 AASGSPGPGEGSAGGEKRST----APSAAASASASAAASSPAGGGAEALELLEHCGVCRE 70
A + SP P + A ++ + PS S S + + A E + L C++
Sbjct: 4 APARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLR----CQQ 59
Query: 71 RLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQC---FSK 127
+ P+LLPCLH+ CS CL + + + CP+C+
Sbjct: 60 CQAEAKCPKLLPCLHTLCSGCL------------------EASGMQCPICQAPWPLGADT 101
Query: 128 DIVENYFMRDSGSKAATDAQ--DANQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVK 185
++N F + + Q DA CT C+++ A +C EC + LC C EAHQ
Sbjct: 102 PALDNVFFESLQRRLSVYRQIVDAQAVCTRCKES--ADFWCFECEQLLCAKCFEAHQ--- 156
Query: 186 YTKDHTVRSTGPAKSR------DGER---TVYCNVHKHEPLVL---FCESCDTLTCRDCQ 233
+ H R +++ DG R ++C+ H L +C C C C
Sbjct: 157 WFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCA 216
Query: 234 L--NAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRV 291
L ++H + + + + Q +L A + + L ++ + ++ +++ Q+ +
Sbjct: 217 LLDSSHSELKCDISAEIQQRQEELDA-MTQALQEQDSAFGAVHAQMHAAVGQLGRARAET 275
Query: 292 QVDVKMAILQIMKELNKRGRVLVN--DA--QKVTEGQQERLERQHWTMTKIQKHQEHILR 347
+ ++ + Q++ + + R L+ DA Q+ E RL R + +I+ + R
Sbjct: 276 EELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQR 335
Query: 348 FASWALESD 356
+A + +
Sbjct: 336 MKCYASDQE 344
>gi|67089149 promyelocytic leukemia protein isoform 1 [Homo sapiens]
Length = 882
Score = 76.3 bits (186), Expect = 1e-13
Identities = 78/369 (21%), Positives = 149/369 (40%), Gaps = 55/369 (14%)
Query: 15 AASGSPGPGEGSAGGEKRST----APSAAASASASAAASSPAGGGAEALELLEHCGVCRE 70
A + SP P + A ++ + PS S S + + A E + L C++
Sbjct: 4 APARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLR----CQQ 59
Query: 71 RLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQC---FSK 127
+ P+LLPCLH+ CS CL + + + CP+C+
Sbjct: 60 CQAEAKCPKLLPCLHTLCSGCL------------------EASGMQCPICQAPWPLGADT 101
Query: 128 DIVENYFMRDSGSKAATDAQ--DANQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVK 185
++N F + + Q DA CT C+++ A +C EC + LC C EAHQ
Sbjct: 102 PALDNVFFESLQRRLSVYRQIVDAQAVCTRCKES--ADFWCFECEQLLCAKCFEAHQ--- 156
Query: 186 YTKDHTVRSTGPAKSR------DGER---TVYCNVHKHEPLVL---FCESCDTLTCRDCQ 233
+ H R +++ DG R ++C+ H L +C C C C
Sbjct: 157 WFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCA 216
Query: 234 L--NAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRV 291
L ++H + + + + Q +L A + + L ++ + ++ +++ Q+ +
Sbjct: 217 LLDSSHSELKCDISAEIQQRQEELDA-MTQALQEQDSAFGAVHAQMHAAVGQLGRARAET 275
Query: 292 QVDVKMAILQIMKELNKRGRVLVN--DA--QKVTEGQQERLERQHWTMTKIQKHQEHILR 347
+ ++ + Q++ + + R L+ DA Q+ E RL R + +I+ + R
Sbjct: 276 EELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQR 335
Query: 348 FASWALESD 356
+A + +
Sbjct: 336 MKCYASDQE 344
>gi|109637788 promyelocytic leukemia protein isoform 5 [Homo
sapiens]
Length = 560
Score = 76.3 bits (186), Expect = 1e-13
Identities = 78/369 (21%), Positives = 149/369 (40%), Gaps = 55/369 (14%)
Query: 15 AASGSPGPGEGSAGGEKRST----APSAAASASASAAASSPAGGGAEALELLEHCGVCRE 70
A + SP P + A ++ + PS S S + + A E + L C++
Sbjct: 4 APARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLR----CQQ 59
Query: 71 RLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQC---FSK 127
+ P+LLPCLH+ CS CL + + + CP+C+
Sbjct: 60 CQAEAKCPKLLPCLHTLCSGCL------------------EASGMQCPICQAPWPLGADT 101
Query: 128 DIVENYFMRDSGSKAATDAQ--DANQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVK 185
++N F + + Q DA CT C+++ A +C EC + LC C EAHQ
Sbjct: 102 PALDNVFFESLQRRLSVYRQIVDAQAVCTRCKES--ADFWCFECEQLLCAKCFEAHQ--- 156
Query: 186 YTKDHTVRSTGPAKSR------DGER---TVYCNVHKHEPLVL---FCESCDTLTCRDCQ 233
+ H R +++ DG R ++C+ H L +C C C C
Sbjct: 157 WFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCA 216
Query: 234 L--NAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRV 291
L ++H + + + + Q +L A + + L ++ + ++ +++ Q+ +
Sbjct: 217 LLDSSHSELKCDISAEIQQRQEELDA-MTQALQEQDSAFGAVHAQMHAAVGQLGRARAET 275
Query: 292 QVDVKMAILQIMKELNKRGRVLVN--DA--QKVTEGQQERLERQHWTMTKIQKHQEHILR 347
+ ++ + Q++ + + R L+ DA Q+ E RL R + +I+ + R
Sbjct: 276 EELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQR 335
Query: 348 FASWALESD 356
+A + +
Sbjct: 336 MKCYASDQE 344
>gi|28195390 tripartite motif-containing 42 [Homo sapiens]
Length = 723
Score = 76.3 bits (186), Expect = 1e-13
Identities = 67/336 (19%), Positives = 134/336 (39%), Gaps = 34/336 (10%)
Query: 64 HCGVCRERLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVC-KQ 122
+C +C RLR +LPC HS C CL A + + ++ CPVC +
Sbjct: 145 NCPMC-SRLR--LHSFMLPCNHSLCEKCLRQLQKHAEVTE-------NFFILICPVCDRS 194
Query: 123 QCF----SKDIVENY--------FMRDSGS-KAATDAQDANQCCTSCEDNAPATSYCVEC 169
C + ENY +M++ G K D C C + A C+ C
Sbjct: 195 HCMPYSNKMQLPENYLHGRLTKRYMQEHGYLKWRFDRSSGPILCQVCRNRRIAYKRCITC 254
Query: 170 SEPLCETCVEAHQRVKYTKDHTVRSTGPAKSRDGERTVYCNVHKHEPLVLFCESCDTLTC 229
LC C++A +DH T S + + C H ++ +C + + L C
Sbjct: 255 RLNLCNDCLKAFHSDVAMQDHVFVDT----SAEEQDEKICIHHPSSRIIEYCRNDNKLLC 310
Query: 230 RDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKE---VRSSIRQVSD 286
C+ + H H L DA + L S + + + E +++S + +
Sbjct: 311 TFCKFSFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLMEFNILKNSFKADKE 370
Query: 287 VQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHIL 346
+++ +++ L++ L ++ ++++ + + +Q+ +E+ + T + ++
Sbjct: 371 AKRK---EIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTTMKVNEMDGLI 427
Query: 347 RFASWALESDNNTALLLSKKLIYFQLHRALKMIVDP 382
++ AL+ A L S K++ Q+ ++ P
Sbjct: 428 AYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRP 463
>gi|223890259 midline 2 isoform 2 [Homo sapiens]
Length = 705
Score = 75.9 bits (185), Expect = 1e-13
Identities = 70/295 (23%), Positives = 115/295 (38%), Gaps = 47/295 (15%)
Query: 57 EALELLEHCGVCRERLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVD 116
E LE C +C E +P LLPC HS C +C A +S G + T
Sbjct: 22 ETLESELTCPICLELFE---DPLLLPCAHSLCFSC---AHRILVSSCSSGESIEPITAFQ 75
Query: 117 CPVC--------------KQQCFSKDIVENY-------------FMRDSGSKAATDAQDA 149
CP C K+ ++I++ + R+ + T
Sbjct: 76 CPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSE 135
Query: 150 NQCCTSCEDNAP--ATSYCVECSEPLCETCVEA-HQRVKYTKDHTVRSTGPAKSRDGERT 206
C CE + P A C+ C C+ C+ A H K H + P G
Sbjct: 136 RIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRG--- 192
Query: 207 VYCNVHKHEPLVLFCESCDTLTCRDCQL-NAHKDHQYQFLEDAVRNQRKLLASLVKRLGD 265
+ C H++E + ++C S D L C C+L H+DHQ L D KL +L L
Sbjct: 193 ITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRF---EKLKQTLEMNL-- 247
Query: 266 KHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKV 320
L K E+ + + ++ + ++V+V+ M ++M+E ++ ++ Q +
Sbjct: 248 --TNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMI 300
>gi|223890257 midline 2 isoform 1 [Homo sapiens]
Length = 735
Score = 75.9 bits (185), Expect = 1e-13
Identities = 70/295 (23%), Positives = 115/295 (38%), Gaps = 47/295 (15%)
Query: 57 EALELLEHCGVCRERLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVD 116
E LE C +C E +P LLPC HS C +C A +S G + T
Sbjct: 22 ETLESELTCPICLELFE---DPLLLPCAHSLCFSC---AHRILVSSCSSGESIEPITAFQ 75
Query: 117 CPVC--------------KQQCFSKDIVENY-------------FMRDSGSKAATDAQDA 149
CP C K+ ++I++ + R+ + T
Sbjct: 76 CPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSE 135
Query: 150 NQCCTSCEDNAP--ATSYCVECSEPLCETCVEA-HQRVKYTKDHTVRSTGPAKSRDGERT 206
C CE + P A C+ C C+ C+ A H K H + P G
Sbjct: 136 RIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRG--- 192
Query: 207 VYCNVHKHEPLVLFCESCDTLTCRDCQL-NAHKDHQYQFLEDAVRNQRKLLASLVKRLGD 265
+ C H++E + ++C S D L C C+L H+DHQ L D KL +L L
Sbjct: 193 ITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRF---EKLKQTLEMNL-- 247
Query: 266 KHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKV 320
L K E+ + + ++ + ++V+V+ M ++M+E ++ ++ Q +
Sbjct: 248 --TNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMI 300
>gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]
Length = 744
Score = 74.7 bits (182), Expect = 3e-13
Identities = 75/364 (20%), Positives = 135/364 (37%), Gaps = 68/364 (18%)
Query: 65 CGVCRERLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQC 124
C +C ER + P++LPCLH+ C CL PA + + CPVC+Q
Sbjct: 23 CSICLERYK---NPKVLPCLHTFCERCLQNYIPAHS------------LTLSCPVCRQTS 67
Query: 125 FSKD-----IVENYFMRDSGSKAATDAQDANQCCTSCEDNAPATSYCVECSEPLCETCVE 179
+ + N+F+ + D + E + T V +PL
Sbjct: 68 ILPEKGVAALQNNFFITN-----LMDVLQRTPGSNAEESSILETVTAVAAGKPLS----- 117
Query: 180 AHQRVKYTKDHTVRSTGPAKSRDGERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKD 239
C H + +C+SC+T CR+C H +
Sbjct: 118 -----------------------------CPNHDGNVMEFYCQSCETAMCRECTEGEHAE 148
Query: 240 HQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAI 299
H L+D V + L + + + + + + + I Q+++ + + D+
Sbjct: 149 HPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTF 208
Query: 300 LQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWALESDNNT 359
++ K LN R VL+ + + + + L+ Q T+ + Q+ + F + AL T
Sbjct: 209 DELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTET 268
Query: 360 ALLLSKKLIYFQLHRALKMIVD---PVEP--HGEMKFQWDLNAWTKSAEAFGKIVAERPG 414
+LL KK Q+ L + D P+ P + ++ F + KS G I+
Sbjct: 269 EVLLVKK----QMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKSIHNLGTILTTNAV 324
Query: 415 TNST 418
+ T
Sbjct: 325 ASET 328
>gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens]
Length = 713
Score = 65.5 bits (158), Expect = 2e-10
Identities = 45/174 (25%), Positives = 73/174 (41%), Gaps = 10/174 (5%)
Query: 628 CRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSLCHVLPDLKEEDGSLSLDGA 687
C VC + G L+ C C FH DCH+P + + WSC+ C +K GS
Sbjct: 537 CEVCCQGGQLLCCGTCPRVFHEDCHIPPV-EAKRMLWSCTFCR----MKRSSGSQQCHHV 591
Query: 688 DSTGVVAKLSPANQRKCERVLLALFCHEPCRPLHQLATDSTFSLDQPGGTLDLTLIRARL 747
T + ++ P +Q KCE +LL +CH P T F++ G + +
Sbjct: 592 SKT-LERQMQPQDQLKCEFLLLKAYCH----PQSSFFTGIPFNIRDYGEPFQEAMWLDLV 646
Query: 748 QEKLSPPYSSPQEFAQDVGRMFKQFNKLTEDKADVQSIIGLQRFFETRMNEAFG 801
+E+L + F +D+ MF+ + Q + L+ FE + + G
Sbjct: 647 KERLITEMYTVAWFVRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVLG 700
>gi|124487387 ring finger protein 207 [Homo sapiens]
Length = 634
Score = 64.3 bits (155), Expect = 4e-10
Identities = 96/406 (23%), Positives = 153/406 (37%), Gaps = 66/406 (16%)
Query: 65 CGVCRERLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQC 124
C +C + P LL C H C+ CL G A DG + CP+C+ Q
Sbjct: 25 CPLCHVQYE---RPCLLDCFHDFCAGCLR-------------GRATDGRLT-CPLCQHQT 67
Query: 125 FSK--------DIVENYFMRDSGSKAATDAQDANQCCTSC-EDNAPATSYCVECSEPLCE 175
K D + + + SG +A C C E + T +C C +PLC
Sbjct: 68 VLKGPSGLPPVDRLLQFLVDSSGD--GVEAVRCANCDLECSEQDVETTYFCNTCGQPLCA 125
Query: 176 TCVEAHQRVKYTKDHTVRSTGPAKSRDGERTVYCNVHKHEPLVLFCESCDTLTCRDCQLN 235
C + R + H + + G +SRD + C +H EP +LF L C C +
Sbjct: 126 RCRDETHRARMFARHDIVALG-QRSRDVPQK--CTLHA-EPYLLFSTDKKLLLCIRCFRD 181
Query: 236 AHK-------DHQYQFLEDAVRNQRKLLA--SLVKRLGDKHATLQKSTKEVRSSIRQVSD 286
K D + +++ R ++ +LA +L + A LQ +EVR S + D
Sbjct: 182 MQKESRAHCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEED 241
Query: 287 VQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQ-HWTMTKIQKHQEHI 345
+ + L +R +L+ Q E + + + Q T + Q H+
Sbjct: 242 A-------IHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHL 294
Query: 346 LRFASWALESDNNTALLLSKKLIYFQLHRALKMIVDP--VEPHGEMKFQWDLNA-WTKSA 402
+ +S+ L N L L Y + R ++ P + P K D A + +
Sbjct: 295 VICSSF-LSLANKAEFL---DLGYELMERLQGIVTRPHHLRPIQSSKIASDHRAEFARCL 350
Query: 403 EAF-----GKIVAERPGTNS----TGPAPMAPPRAPGPLSKQGSGS 439
E ++ A G N+ GP + P P P+ K SGS
Sbjct: 351 EPLLLLGPRRVAAAASGANTLAGGLGPKALTGPHCPSPVGKM-SGS 395
>gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens]
Length = 867
Score = 62.8 bits (151), Expect = 1e-09
Identities = 49/178 (27%), Positives = 76/178 (42%), Gaps = 17/178 (9%)
Query: 628 CRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSLCHVLPDLKEEDGSLSLDGA 687
C VC+ G+L C+ C FH DCH+P + + W+C C +KE GS
Sbjct: 693 CEVCRDGGELFCCDTCSRVFHEDCHIPPV-EAERTPWNCIFCR----MKESPGSQQC-CQ 746
Query: 688 DSTGVVAKLSPANQRKCERVLLALFCHEPCR-----PLHQLATDSTFSLDQPGGTLDLTL 742
+S + ++ P Q KCE +LL ++C P + ++ L +P + L
Sbjct: 747 ESEVLERQMCPEEQLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEP---MWLDK 803
Query: 743 IRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTEDKADVQSIIGLQRFFETRMNEAF 800
I+ RL E Y + F QD+ +F+ + K Q L+ FE E F
Sbjct: 804 IKKRLNEH---GYPQVEGFVQDMRLIFQNHRASYKYKDFGQMGFRLEAEFEKNFKEVF 858
>gi|134133279 SP140 nuclear body protein-like [Homo sapiens]
Length = 580
Score = 62.8 bits (151), Expect = 1e-09
Identities = 49/178 (27%), Positives = 77/178 (43%), Gaps = 17/178 (9%)
Query: 628 CRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSLCHVLPDLKEEDGSLSLDGA 687
C VC+ G+L C+ C FH DCH+P ++ W+C C +KE GS
Sbjct: 406 CEVCRDGGELFCCDTCSRVFHEDCHIPPVES-EKTPWNCIFCR----MKESPGSQQC-CQ 459
Query: 688 DSTGVVAKLSPANQRKCERVLLALFCHEPCR-----PLHQLATDSTFSLDQPGGTLDLTL 742
+S + ++ P Q KCE +LL ++C P + ++ L +P + L
Sbjct: 460 ESEVLERQMCPEEQLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEP---MWLDK 516
Query: 743 IRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTEDKADVQSIIGLQRFFETRMNEAF 800
I+ RL E Y + F QD+ +F+ + K Q + L+ FE E F
Sbjct: 517 IKKRLNEH---GYPQVEGFVQDMRLIFQNHRASYKYKDFGQMGLRLEAEFEKDFKEVF 571
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,982,638
Number of Sequences: 37866
Number of extensions: 2210883
Number of successful extensions: 20268
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 307
Number of HSP's successfully gapped in prelim test: 760
Number of HSP's that attempted gapping in prelim test: 14271
Number of HSP's gapped (non-prelim): 5730
length of query: 835
length of database: 18,247,518
effective HSP length: 111
effective length of query: 724
effective length of database: 14,044,392
effective search space: 10168139808
effective search space used: 10168139808
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.