Guide to the Human Genome
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Name: PML Sequence: fasta or formatted (882aa) NCBI GI: 67089149
Description:

promyelocytic leukemia protein isoform 1

Referenced in:

Nucleus and Nucleolus
Tripartite Motif Family

Other entries for this name:
alt prot [560aa] promyelocytic leukemia protein isoform 5
alt prot [829aa] promyelocytic leukemia protein isoform 9
alt prot [423aa] promyelocytic leukemia protein isoform 7
alt prot [585aa] promyelocytic leukemia protein isoform 10
alt prot [633aa] promyelocytic leukemia protein isoform 6
alt prot [435aa] promyelocytic leukemia protein isoform 8
alt prot [611aa] promyelocytic leukemia protein isoform 2
alt prot [781aa] promyelocytic leukemia protein isoform 11
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            10.9         96           2
 C cysteine            3.3         29           2
 D aspartate           4.2         37           2
 E glutamate           8.4         74           3
 F phenylalanine       3.7         33           2
 G glycine             4.3         38           2
 H histidine           1.8         16           1
 I isoleucine          2.5         22           1
 K lysine              3.4         30           2
 L leucine            10.5         93           2
 M methionine          1.7         15           1
 N asparagine          2.2         19           2
 P proline             7.5         66           3
 Q glutamine           7.1         63           2
 R arginine            7.8         69           2
 S serine              9.4         83           3
 T threonine           3.4         30           3
 V valine              5.7         50           3
 W tryptophan          0.6          5           1
 Y tyrosine            1.6         14           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   promyelocytic leukemia protein isoform 1 
PML                   0.708   promyelocytic leukemia protein isoform 6 
PML                   0.655   promyelocytic leukemia protein isoform 9 
PML                   0.653   promyelocytic leukemia protein isoform 2 
PML                   0.641   promyelocytic leukemia protein isoform 10 
PML                   0.634   promyelocytic leukemia protein isoform 5 
PML                   0.588   promyelocytic leukemia protein isoform 11 
PML                   0.481   promyelocytic leukemia protein isoform 8 
PML                   0.481   promyelocytic leukemia protein isoform 7 
LOC652346             0.280   PREDICTED: similar to PML protein 
LOC652671             0.107   PREDICTED: similar to promyelocytic leukemia protei...
TRIM56                0.036   tripartite motif-containing 56 
TRIM33                0.034   tripartite motif-containing 33 protein isoform beta ...
TRIM33                0.034   tripartite motif-containing 33 protein isoform alpha...
TRIM24                0.031   transcriptional intermediary factor 1 alpha isoform ...
TRIM24                0.031   transcriptional intermediary factor 1 alpha isoform ...
TRIM28                0.029   tripartite motif-containing 28 protein 
TRIM45                0.029   tripartite motif-containing 45 isoform 1 
TRIM45                0.029   tripartite motif-containing 45 isoform 2 
TRIM2                 0.024   tripartite motif-containing 2 isoform 1 
RNF207                0.023   ring finger protein 207 
TRIM2                 0.023   tripartite motif-containing 2 isoform 2 
TRIM3                 0.018   tripartite motif-containing 3 
TRIM3                 0.018   tripartite motif-containing 3 
TRIM25                0.017   tripartite motif-containing 25 
TRIM46                0.016   tripartite motif-containing 46 
TRIM66                0.013   tripartite motif-containing 66 
TRIM10                0.013   tripartite motif-containing 10 isoform 1 
TRIM10                0.013   tripartite motif-containing 10 isoform 2 
TRIM39                0.013   tripartite motif-containing 39 isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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