BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5031855 lymphocyte cytosolic protein 2 [Homo sapiens] (533 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5031855 lymphocyte cytosolic protein 2 [Homo sapiens] 1115 0.0 gi|7019535 B-cell linker isoform 1 [Homo sapiens] 143 4e-34 gi|166235901 B-cell linker isoform 2 [Homo sapiens] 127 3e-29 gi|193083221 mast cell immunoreceptor signal transducer [Homo sa... 127 3e-29 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 84 3e-16 gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 84 3e-16 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 77 4e-14 gi|38348280 SH2 domain containing 6 [Homo sapiens] 73 6e-13 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 72 2e-12 gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 70 4e-12 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 69 1e-11 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 68 2e-11 gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 68 2e-11 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 67 4e-11 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 65 2e-10 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 65 2e-10 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 65 2e-10 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 65 2e-10 gi|151301053 RNA binding motif protein 33 [Homo sapiens] 63 8e-10 gi|18079216 CASK interacting protein 1 [Homo sapiens] 62 1e-09 gi|160707881 formin 2 [Homo sapiens] 62 1e-09 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 60 4e-09 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 60 4e-09 gi|47132519 Ras association and pleckstrin homology domains 1 is... 60 4e-09 gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 60 4e-09 gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 60 5e-09 gi|110349719 titin isoform N2-A [Homo sapiens] 60 6e-09 gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho... 60 6e-09 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 59 8e-09 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 59 8e-09 >gi|5031855 lymphocyte cytosolic protein 2 [Homo sapiens] Length = 533 Score = 1115 bits (2885), Expect = 0.0 Identities = 533/533 (100%), Positives = 533/533 (100%) Query: 1 MALRNVPFRSEVLGWDPDSLADYFKKLNYKDCEKAVKKYHIDGARFLNLTENDIQKFPKL 60 MALRNVPFRSEVLGWDPDSLADYFKKLNYKDCEKAVKKYHIDGARFLNLTENDIQKFPKL Sbjct: 1 MALRNVPFRSEVLGWDPDSLADYFKKLNYKDCEKAVKKYHIDGARFLNLTENDIQKFPKL 60 Query: 61 RVPILSKLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQ 120 RVPILSKLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQ Sbjct: 61 RVPILSKLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQ 120 Query: 121 DGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSG 180 DGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSG Sbjct: 121 DGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSG 180 Query: 181 KTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTK 240 KTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTK Sbjct: 181 KTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTK 240 Query: 241 PPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPL 300 PPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPL Sbjct: 241 PPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPL 300 Query: 301 PGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHM 360 PGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHM Sbjct: 301 PGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHM 360 Query: 361 PGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNE 420 PGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNE Sbjct: 361 PGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNE 420 Query: 421 EWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKES 480 EWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKES Sbjct: 421 EWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKES 480 Query: 481 QVYLLGTGLRGKEDFLSVSDIIDYFRKMPLLLIDGKNRGSRYQCTLTHAAGYP 533 QVYLLGTGLRGKEDFLSVSDIIDYFRKMPLLLIDGKNRGSRYQCTLTHAAGYP Sbjct: 481 QVYLLGTGLRGKEDFLSVSDIIDYFRKMPLLLIDGKNRGSRYQCTLTHAAGYP 533 >gi|7019535 B-cell linker isoform 1 [Homo sapiens] Length = 456 Score = 143 bits (360), Expect = 4e-34 Identities = 135/502 (26%), Positives = 192/502 (38%), Gaps = 99/502 (19%) Query: 54 IQKFPKLRVPILSKLSQ------EINKNEE------RRSIFTRKPQVPRFPEETESHEED 101 + K K+ VP KL Q +I NE ++ P VPR +ES ++ Sbjct: 1 MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE 60 Query: 102 NGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSIL 161 WS + DYE+P++ D E Y P EE D YEPPP E + Sbjct: 61 EEQWSDDFDSDYENPDEHSDSEM---YVMPAEENA-----DDSYEPPPVEQET---RPVH 109 Query: 162 PAKPFPNSNSMYIDR-------PPSGKT-PQQPPVPPQRPMAALPPPPAGRNHSPLPPPQ 213 PA PF YID PP KT P +P P ++ P P PP+ Sbjct: 110 PALPFARGE--YIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPK 167 Query: 214 TNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGR 273 + +P D + P + S P ++ P P S P+ P G Sbjct: 168 PK----GLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGT 223 Query: 274 SLGEHLPKIQKPPLPPTTERHERSSPLP--GKKPPVPKHGWGPDRRENDEDDVHQRPLPQ 331 + G + + PP SPLP GKKP P ++N ++P+P Sbjct: 224 ASGRNSGAWETKSPPPAAP-----SPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIP- 277 Query: 332 PALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPI 391 A SS Q A P F PP Sbjct: 278 -------------------------------AERHRGSSHRQEAVQSPVF-------PPA 299 Query: 392 RAEGRNFPLPLPNKPRPPSPA----------------EEENSLNEEWYVSYITRPEAEAA 435 + + P+PLP +P +E L + WY R AE A Sbjct: 300 QKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEA 359 Query: 436 LRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLRGKEDF 495 L + N+DG+FL+R SS + PY L+V + +VYNI +R+ + ++ Y LG G+E F Sbjct: 360 LHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYF 419 Query: 496 LSVSDIIDYFRKMPLLLIDGKN 517 SV++II + PL+LID +N Sbjct: 420 GSVAEIIRNHQHSPLVLIDSQN 441 >gi|166235901 B-cell linker isoform 2 [Homo sapiens] Length = 433 Score = 127 bits (318), Expect = 3e-29 Identities = 132/502 (26%), Positives = 187/502 (37%), Gaps = 122/502 (24%) Query: 54 IQKFPKLRVPILSKLSQ------EINKNEE------RRSIFTRKPQVPRFPEETESHEED 101 + K K+ VP KL Q +I NE ++ P VPR +ES ++ Sbjct: 1 MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE 60 Query: 102 NGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSIL 161 WS + DYE+P++ D E Y P EE D YEPPP E + Sbjct: 61 EEQWSDDFDSDYENPDEHSDSE---MYVMPAEENA-----DDSYEPPPVEQE---TRPVH 109 Query: 162 PAKPFPNSNSMYIDR-------PPSGKT-PQQPPVPPQRPMAALPPPPAGRNHSPLPPPQ 213 PA PF + YID PP KT P +P P ++ P P PP+ Sbjct: 110 PALPF--ARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPK 167 Query: 214 TNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGR 273 + +P D + P + S P ++ GR Sbjct: 168 PK----GLLEDEADYVVPVEDNDENYIHPTESSSPPPEK-------------------GR 204 Query: 274 SLGEHLPKIQKPPLPPTTERHERSSPLP--GKKPPVPKHGWGPDRRENDEDDVHQRPLPQ 331 + G K P P SPLP GKKP P ++N ++P+P Sbjct: 205 NSGAWETKSPPPAAP---------SPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIP- 254 Query: 332 PALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPI 391 A SS Q A P F PP Sbjct: 255 -------------------------------AERHRGSSHRQEAVQSPVF-------PPA 276 Query: 392 RAEGRNFPLPLPNKPRPPSPA----------------EEENSLNEEWYVSYITRPEAEAA 435 + + P+PLP +P +E L + WY R AE A Sbjct: 277 QKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEA 336 Query: 436 LRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLRGKEDF 495 L + N+DG+FL+R SS + PY L+V + +VYNI +R+ + ++ Y LG G+E F Sbjct: 337 LHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYF 396 Query: 496 LSVSDIIDYFRKMPLLLIDGKN 517 SV++II + PL+LID +N Sbjct: 397 GSVAEIIRNHQHSPLVLIDSQN 418 >gi|193083221 mast cell immunoreceptor signal transducer [Homo sapiens] Length = 428 Score = 127 bits (318), Expect = 3e-29 Identities = 119/399 (29%), Positives = 170/399 (42%), Gaps = 61/399 (15%) Query: 142 DADYEPPPSNDEEALQN-SILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPP 200 D DY+ P EE Q+ ILPA+P S Y D K P+P + Sbjct: 66 DDDYDDPELRMEETWQSIKILPARPIKESE--YADTHYF-KVAMDTPLPLDTRTSISIGQ 122 Query: 201 PAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKK 260 P + L + RS+N K + R K PL P R TL KK Sbjct: 123 PTWNTQTRLERVDKPISKDVRSQNIK-----GDASVRKNKIPL-----PPPRPLITLPKK 172 Query: 261 ------PPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGP 314 P S +P + S P++Q+ +P + S L +K P Sbjct: 173 YQPLPPEPESSRPPL----SQRHTFPEVQR--MPSQISLRDLSEVLEAEKVP-------- 218 Query: 315 DRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQS 374 H + P+ L + NT +P + +F+ SN S Sbjct: 219 ----------HNQRKPESTHLLENQNT-----------QEIPLAISSSSFTTSNHSVQNR 257 Query: 375 ASLPPYFSQGPSN-RPPIRAEGRNFPLPLPNKP-RPPSP--AEEENSLNEEWYVSYITRP 430 P +PP LP RPP P ++ ++ + EWY+ +R Sbjct: 258 DHRGGMQPCSPQRCQPPASCSPHENILPYKYTSWRPPFPKRSDRKDVQHNEWYIGEYSRQ 317 Query: 431 EAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLR 490 E A K N+DG+FLVRD S K+ PYVL V Y++KVYN++IR+ + +Q + LGTGLR Sbjct: 318 AVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFLERNQQFALGTGLR 377 Query: 491 GKEDFLSVSDIIDYFRKMPLLLIDGKNRGS--RYQCTLT 527 G E F SV DII++++ P++LIDGK++ R QC LT Sbjct: 378 GDEKFDSVEDIIEHYKNFPIILIDGKDKTGVHRKQCHLT 416 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 84.0 bits (206), Expect = 3e-16 Identities = 80/280 (28%), Positives = 100/280 (35%), Gaps = 43/280 (15%) Query: 151 NDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVP----------PQRPMAALPPP 200 ND + +LP P S S PPSG P + PVP PQR P P Sbjct: 119 NDSGGSRPPLLP--PGGRSTSAKPFSPPSG--PGRFPVPSPGHRSGPPEPQRNRMPPPRP 174 Query: 201 PAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKK 260 G +PPP + P +S H P P R P Sbjct: 175 DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPG---------------PTP 219 Query: 261 PPFSDKPSIPAGRS------LGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGP 314 PPF G L P +PPLPPT R P P PP P Sbjct: 220 PPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP---PPPPV----- 271 Query: 315 DRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQS 374 R + + P PQ P+ S PS S++ P P PS P S+S ++ Sbjct: 272 GNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDET 331 Query: 375 ASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEE 414 LP S+ PP+ + GR+ PLP P RPP P + Sbjct: 332 PRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRD 371 Score = 59.7 bits (143), Expect = 6e-09 Identities = 50/184 (27%), Positives = 69/184 (37%), Gaps = 27/184 (14%) Query: 139 VEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALP 198 ++D PPP + ++ +P P N+ P + Q PP P Sbjct: 260 LDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP---------P 310 Query: 199 PPPAGRNHSPLPPPQTNHEEPSR------SRNHKTAKLPAPSIDRSTKPPLDRSLAPFDR 252 PPP+ PLPP + ++E R S + T LP+P PP P R Sbjct: 311 PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVR 370 Query: 253 EPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGW 312 +P G+ P P + S LP P LP R SP G +PP+P Sbjct: 371 DP--PGRSGPLPPPPPVSRNGSTSRALP--ATPQLP---SRSGVDSPRSGPRPPLP---- 419 Query: 313 GPDR 316 PDR Sbjct: 420 -PDR 422 Score = 50.1 bits (118), Expect = 5e-06 Identities = 54/219 (24%), Positives = 86/219 (39%), Gaps = 28/219 (12%) Query: 135 EEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPM 194 E P + +PP + +S P P P S PPS + P PQR + Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNL 339 Query: 195 ---AALPPPPAGRNHSPLPPPQTNHEEPS-RSRNHKTAKLPAPSIDRSTKPPLDRSLAPF 250 ++ PP P+ PLPPP + P R ++ LP P PP+ R+ + Sbjct: 340 SLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPP-------PPVSRNGSTS 392 Query: 251 DREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKH 310 P T P + + + RS +PPLPP +R +P P ++ Sbjct: 393 RALPAT----PQLPSRSGVDSPRS-------GPRPPLPP--DRPSAGAPPPPPPSTSIRN 439 Query: 311 GWGPDRREND-EDDVHQRP---LPQPALLPMSSNTFPSR 345 G+ E++ E + P LP P ++ ++PS+ Sbjct: 440 GFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSK 478 Score = 47.4 bits (111), Expect = 3e-05 Identities = 39/118 (33%), Positives = 46/118 (38%), Gaps = 28/118 (23%) Query: 131 PNEEEEAPVED----DADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQP 186 P+E PV D PPP + LPA P S S +D P SG +P Sbjct: 361 PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRS-GVDSPRSG---PRP 416 Query: 187 PVPPQRPMAALPPPPAGRNHSPLPPPQTN-----------HEEPSRSRNHKTAKLPAP 233 P+PP RP A PPP PPP T+ E SR H + LP P Sbjct: 417 PLPPDRPSAGAPPP---------PPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPP 465 Score = 41.6 bits (96), Expect = 0.002 Identities = 52/170 (30%), Positives = 67/170 (39%), Gaps = 43/170 (25%) Query: 131 PNEEEEAPVEDDADYEP-PPSNDEEALQNSILPAKPFPNSN--SMYIDRPPSGKTPQQPP 187 P+ +AP P PP + N P P N + S P G++ PP Sbjct: 300 PSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPP 359 Query: 188 VPPQRPMAALPPP---PAGRNHSPLPPPQTNHEEPSRSRNHKTAK-LPA-PSIDRSTKPP 242 P +RP PPP P GR+ PLPPP P SRN T++ LPA P + + Sbjct: 360 PPSERP----PPPVRDPPGRS-GPLPPP------PPVSRNGSTSRALPATPQLPSRSGVD 408 Query: 243 LDRSLAPFDREPFTLGKKPPF-SDKPSIPAGRSLGEHLPKIQKPPLPPTT 291 RS G +PP D+PS A PP PP+T Sbjct: 409 SPRS-----------GPRPPLPPDRPSAGA------------PPPPPPST 435 >gi|38373695 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 84.0 bits (206), Expect = 3e-16 Identities = 80/280 (28%), Positives = 100/280 (35%), Gaps = 43/280 (15%) Query: 151 NDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVP----------PQRPMAALPPP 200 ND + +LP P S S PPSG P + PVP PQR P P Sbjct: 119 NDSGGSRPPLLP--PGGRSTSAKPFSPPSG--PGRFPVPSPGHRSGPPEPQRNRMPPPRP 174 Query: 201 PAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKK 260 G +PPP + P +S H P P R P Sbjct: 175 DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPG---------------PTP 219 Query: 261 PPFSDKPSIPAGRS------LGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGP 314 PPF G L P +PPLPPT R P P PP P Sbjct: 220 PPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP---PPPPV----- 271 Query: 315 DRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQS 374 R + + P PQ P+ S PS S++ P P PS P S+S ++ Sbjct: 272 GNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDET 331 Query: 375 ASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEE 414 LP S+ PP+ + GR+ PLP P RPP P + Sbjct: 332 PRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRD 371 Score = 59.7 bits (143), Expect = 6e-09 Identities = 50/184 (27%), Positives = 69/184 (37%), Gaps = 27/184 (14%) Query: 139 VEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALP 198 ++D PPP + ++ +P P N+ P + Q PP P Sbjct: 260 LDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP---------P 310 Query: 199 PPPAGRNHSPLPPPQTNHEEPSR------SRNHKTAKLPAPSIDRSTKPPLDRSLAPFDR 252 PPP+ PLPP + ++E R S + T LP+P PP P R Sbjct: 311 PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVR 370 Query: 253 EPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGW 312 +P G+ P P + S LP P LP R SP G +PP+P Sbjct: 371 DP--PGRSGPLPPPPPVSRNGSTSRALP--ATPQLP---SRSGVDSPRSGPRPPLP---- 419 Query: 313 GPDR 316 PDR Sbjct: 420 -PDR 422 Score = 50.1 bits (118), Expect = 5e-06 Identities = 54/219 (24%), Positives = 86/219 (39%), Gaps = 28/219 (12%) Query: 135 EEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPM 194 E P + +PP + +S P P P S PPS + P PQR + Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNL 339 Query: 195 ---AALPPPPAGRNHSPLPPPQTNHEEPS-RSRNHKTAKLPAPSIDRSTKPPLDRSLAPF 250 ++ PP P+ PLPPP + P R ++ LP P PP+ R+ + Sbjct: 340 SLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPP-------PPVSRNGSTS 392 Query: 251 DREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKH 310 P T P + + + RS +PPLPP +R +P P ++ Sbjct: 393 RALPAT----PQLPSRSGVDSPRS-------GPRPPLPP--DRPSAGAPPPPPPSTSIRN 439 Query: 311 GWGPDRREND-EDDVHQRP---LPQPALLPMSSNTFPSR 345 G+ E++ E + P LP P ++ ++PS+ Sbjct: 440 GFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSK 478 Score = 47.4 bits (111), Expect = 3e-05 Identities = 39/118 (33%), Positives = 46/118 (38%), Gaps = 28/118 (23%) Query: 131 PNEEEEAPVED----DADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQP 186 P+E PV D PPP + LPA P S S +D P SG +P Sbjct: 361 PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRS-GVDSPRSG---PRP 416 Query: 187 PVPPQRPMAALPPPPAGRNHSPLPPPQTN-----------HEEPSRSRNHKTAKLPAP 233 P+PP RP A PPP PPP T+ E SR H + LP P Sbjct: 417 PLPPDRPSAGAPPP---------PPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPP 465 Score = 41.6 bits (96), Expect = 0.002 Identities = 52/170 (30%), Positives = 67/170 (39%), Gaps = 43/170 (25%) Query: 131 PNEEEEAPVEDDADYEP-PPSNDEEALQNSILPAKPFPNSN--SMYIDRPPSGKTPQQPP 187 P+ +AP P PP + N P P N + S P G++ PP Sbjct: 300 PSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPP 359 Query: 188 VPPQRPMAALPPP---PAGRNHSPLPPPQTNHEEPSRSRNHKTAK-LPA-PSIDRSTKPP 242 P +RP PPP P GR+ PLPPP P SRN T++ LPA P + + Sbjct: 360 PPSERP----PPPVRDPPGRS-GPLPPP------PPVSRNGSTSRALPATPQLPSRSGVD 408 Query: 243 LDRSLAPFDREPFTLGKKPPF-SDKPSIPAGRSLGEHLPKIQKPPLPPTT 291 RS G +PP D+PS A PP PP+T Sbjct: 409 SPRS-----------GPRPPLPPDRPSAGA------------PPPPPPST 435 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 77.0 bits (188), Expect = 4e-14 Identities = 68/242 (28%), Positives = 84/242 (34%), Gaps = 21/242 (8%) Query: 177 PPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSID 236 P G PQ PP PP +P PPP G PPP + P +K P P Sbjct: 41 PQGGNKPQGPPSPPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 98 Query: 237 RSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHE- 295 + P D+S +P G P ++P P P KP PP ++ Sbjct: 99 QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP--------PPPGKPQGPPPQGGNKP 150 Query: 296 RSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKP------ 349 + P PGK P G R Q P PQ P P + P Sbjct: 151 QGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 210 Query: 350 SPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPP 409 P P P G + ++ QSA PP QGP PP P P P KP+ P Sbjct: 211 KPQGPPPPGKPQGPPPQGDNK-SQSARSPPGKPQGP---PPQGGNQPQGPPPPPGKPQGP 266 Query: 410 SP 411 P Sbjct: 267 PP 268 Score = 69.3 bits (168), Expect = 8e-12 Identities = 77/296 (26%), Positives = 96/296 (32%), Gaps = 47/296 (15%) Query: 122 GEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGK 181 G+ G + + P PPP D+ S P KP P G Sbjct: 76 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP-PGKPQGPP-------PQGGN 127 Query: 182 TPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKP 241 PQ PP PP +P PPP G N PPP + P ++K+ RS++ Sbjct: 128 QPQGPPPPPGKPQG---PPPQGGNKPQGPPPPGKPQGPPPQGDNKS---------RSSRS 175 Query: 242 PLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLP 301 P + P P G +P P P G+ G PP + P P Sbjct: 176 PPGKPQGP----PPQGGNQP---QGPPPPPGKPQGP----------PPQGGNKPQGPPPP 218 Query: 302 GKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKP------SPMNPL 355 GK P G + Q P PQ P P + P P P Sbjct: 219 GKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 278 Query: 356 PSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSP 411 P G + S S S PP QGP PP P P P KP+ P P Sbjct: 279 PPGKPQGPPPQGGSKSRSSRS-PPGKPQGP---PPQGGNQPQGPPPPPGKPQGPPP 330 Score = 68.6 bits (166), Expect = 1e-11 Identities = 73/295 (24%), Positives = 93/295 (31%), Gaps = 53/295 (17%) Query: 122 GEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGK 181 G+ G + + P PPP D ++ + P KP P G Sbjct: 137 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPP-------PQGGN 189 Query: 182 TPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKP 241 PQ PP PP +P PPP G N PPP + P ++K+ +P P Sbjct: 190 QPQGPPPPPGKPQG---PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPP 246 Query: 242 PLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLP 301 P G +P P P G+ G PP + P P Sbjct: 247 PQG-------------GNQP---QGPPPPPGKPQGP----------PPQGGNKPQGPPPP 280 Query: 302 GKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKP------SPMNPL 355 GK P G R Q P PQ P P + P P P Sbjct: 281 GKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 340 Query: 356 PSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPS 410 P G + S +SA PP QGP + EG N P P PP+ Sbjct: 341 PPGKPQGPPPQGGSK-SRSARSPPGKPQGPPQQ-----EGNN-----PQGPPPPA 384 Score = 39.3 bits (90), Expect = 0.009 Identities = 28/97 (28%), Positives = 36/97 (37%), Gaps = 8/97 (8%) Query: 122 GEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPF----PNSNSMYIDRP 177 G+ G + + P PPP ++ P KP N+ P Sbjct: 323 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPP 382 Query: 178 PSGKTPQQPPVPPQ-RPMAALPPPPAGRNHSPLPPPQ 213 P+G PQQP PP +P PP GR P PPQ Sbjct: 383 PAGGNPQQPQAPPAGQPQGPPRPPQGGR---PSRPPQ 416 Score = 38.1 bits (87), Expect = 0.020 Identities = 42/160 (26%), Positives = 54/160 (33%), Gaps = 23/160 (14%) Query: 265 DKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKK-----PPVPKHGWGPDRREN 319 + PS+ AG G KP PP+ + P G PP P GP + Sbjct: 27 ESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 86 Query: 320 DEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPP 379 ++ P P + RS P P P + PQ PP Sbjct: 87 NKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG----------GNQPQGPPPPP 136 Query: 380 YFSQGPSNRPPIRAEGRNFPL--PLPNKPRPPSPAEEENS 417 QGP PP +G N P P P KP+ P P + S Sbjct: 137 GKPQGP---PP---QGGNKPQGPPPPGKPQGPPPQGDNKS 170 Score = 33.5 bits (75), Expect = 0.50 Identities = 41/162 (25%), Positives = 50/162 (30%), Gaps = 23/162 (14%) Query: 85 KPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDAD 144 KPQ P P + + G S SP G+ G + + P Sbjct: 273 KPQGPPPPGKPQGPPPQGGSKSRSSR----SP----PGKPQGPPPQGGNQPQGPPPPPGK 324 Query: 145 YEPPPSNDEEALQNSILPAKPF---PNSNSMYID-RPPSGKTPQQPPVPPQRPMAALPPP 200 + PP Q P KP P S R P GK PQ PP PPP Sbjct: 325 PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGK-PQGPPQQEGNNPQGPPPP 383 Query: 201 PAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPP 242 G P PP + P R P R ++PP Sbjct: 384 AGGNPQQPQAPPAGQPQGPPR----------PPQGGRPSRPP 415 >gi|38348280 SH2 domain containing 6 [Homo sapiens] Length = 175 Score = 73.2 bits (178), Expect = 6e-13 Identities = 49/145 (33%), Positives = 72/145 (49%), Gaps = 2/145 (1%) Query: 378 PPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALR 437 PP P + EGR LP S AE+ + L + WY R E+AL Sbjct: 21 PPPHPTPPQLNNLLLLEGRKSSLPSVAPTGSASAAEDSDLLTQPWYSGNCDRYAVESALL 80 Query: 438 KINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLRGKED-FL 496 + +DG + VR SS + P+ L VL + +V+NI IR + Y LG R +E+ F Sbjct: 81 HLQKDGAYTVRPSSGPHGSQPFTLAVLLRGRVFNIPIRRLDGGRHYALGREGRNREELFS 140 Query: 497 SVSDIIDYFRKMPLLLIDGKNRGSR 521 SV+ ++ +F PL L+D ++ GSR Sbjct: 141 SVAAMVQHFMWHPLPLVD-RHSGSR 164 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 71.6 bits (174), Expect = 2e-12 Identities = 89/370 (24%), Positives = 133/370 (35%), Gaps = 46/370 (12%) Query: 73 NKNEERRSIFTRKPQVPRFPEETESHEEDNGGW----SSFEEDDYESPNDDQDGEDDGDY 128 +K E+R + P+ PR E +ES EED GG S ++ + Q D G Sbjct: 442 HKGTEKRESPSPAPK-PRKVELSES-EEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGS- 498 Query: 129 ESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPF-PNSNSMYIDRPPSGKTPQQPP 187 S + E+E P N E + P++ P+ + P G+ + P Sbjct: 499 -SSSSEDERPKRSHV------KNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPS 551 Query: 188 VPP-QRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDR--------- 237 PP +R + P PP R +P PPP+ P R + + +P I R Sbjct: 552 PPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPK 611 Query: 238 ----STKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTER 293 S PP R +P + PP + S P + L + P+ Sbjct: 612 RRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSS-PVTKRRSPSLSSKHRKGSSPSRST 670 Query: 294 HERSSPLPGK------KPPVPKHGWGPDR-RENDEDDVHQRPLPQPALLP---MSSNTFP 343 E SP P K +P P+ P R +R P P+ P +S P Sbjct: 671 REARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 730 Query: 344 SRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLP----PYFSQGPSNR--PPIRAEGRN 397 + K + +P + + S S S P + P P SQ PS P + + Sbjct: 731 KKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAK 790 Query: 398 FPLPLPNKPR 407 P P P+ PR Sbjct: 791 SPTPSPSPPR 800 Score = 45.4 bits (106), Expect = 1e-04 Identities = 68/340 (20%), Positives = 110/340 (32%), Gaps = 26/340 (7%) Query: 84 RKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDA 143 +K + P PE + +E + ++ D + P + E + P+ E+ + E + Sbjct: 216 KKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEP----KEPSPEKNSKKEKEK 271 Query: 144 DYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAG 203 + P S ++ P +P++ P P +RP PP Sbjct: 272 EKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPP-- 329 Query: 204 RNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPF 263 P PP P R R +A L S S+ RS +P + P P Sbjct: 330 -RRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSS----RSRSPPKKPPKRTSSPPRK 384 Query: 264 SDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDR---REND 320 + + S A H P P PP RH +P + + P R + Sbjct: 385 TRRLSPSASPPRRRHRP--SPPATPPPKTRHS-PTPQQSNRTRKSRVSVSPGRTSGKVTK 441 Query: 321 EDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPY 380 +R P PA P S K M S + N Q +S Sbjct: 442 HKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQN----QQSSSDSG 497 Query: 381 FSQGPSNRPPIRAEGRNFPL-----PLPNKPRPPSPAEEE 415 S + P R+ +N + P++ PSP + + Sbjct: 498 SSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQ 537 Score = 40.8 bits (94), Expect = 0.003 Identities = 58/242 (23%), Positives = 90/242 (37%), Gaps = 25/242 (10%) Query: 204 RNHSPLPPPQTNHEEPSRS--RNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKP 261 R+HS P +T PS + + KT +LP PS+ + +P + + + D + Sbjct: 195 RSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSV-KVKEPSVQEATSTSDILKVPKPEPI 253 Query: 262 PFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKH-----GWGPDR 316 P +PS + K + + R S P P +H + P R Sbjct: 254 PEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRR 313 Query: 317 RENDEDDVHQRPLPQPALLPMSSNTFP--SRSTKPSPMNPLPSSHMPGAFSESNSSF--- 371 R + +RP P+ P P RS P S+ + G+ S S+SS Sbjct: 314 RPSP----RRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRS 369 Query: 372 -----PQSASLPPYFSQ--GPSNRPPIRAEGRNFPLPLPNKPR-PPSPAEEENSLNEEWY 423 P+ S PP ++ PS PP R + P P K R P+P + + Sbjct: 370 PPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVS 429 Query: 424 VS 425 VS Sbjct: 430 VS 431 >gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo sapiens] Length = 247 Score = 70.5 bits (171), Expect = 4e-12 Identities = 61/225 (27%), Positives = 81/225 (36%), Gaps = 19/225 (8%) Query: 176 RPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSI 235 RP G PQ+PP PP +P PPP G N S PPP E + ++ P P Sbjct: 40 RPQGGNQPQRPPPPPGKPQG---PPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHP 96 Query: 236 DRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHE 295 + +PP P P ++P G P KP PP ++ Sbjct: 97 GKPERPPPQGGNQSQGTPP-----PPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQ 151 Query: 296 RSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKP-SPMNP 354 P PP P GP +E ++ + P +P P P P P P Sbjct: 152 SQGP-----PPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGP 206 Query: 355 LPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFP 399 P+ P + PQ PP QG RPP A+G+ P Sbjct: 207 PPAGGNPQQPQAPPAGKPQGPPPPP---QG--GRPPRPAQGQQPP 246 Score = 50.8 bits (120), Expect = 3e-06 Identities = 51/207 (24%), Positives = 66/207 (31%), Gaps = 30/207 (14%) Query: 132 NEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPF---PNSNSMYIDRPPSGKTPQQPP- 187 N+ + P PPP ++ P KP P + PP P++PP Sbjct: 45 NQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPP 104 Query: 188 --------VPPQRPMAALPPPPAGRNHSPLPPPQTNHEE-PSRSRNHKTAKLPAP----- 233 PP PPP G PPP E P + N P P Sbjct: 105 QGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEG 164 Query: 234 ------SIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPL 287 + RS + P + P +E G KP P P G P Q+P Sbjct: 165 PPPQEGNKSRSARSPPGKPQGPPQQE----GNKPQGPPPPGKPQGPPPAGGNP--QQPQA 218 Query: 288 PPTTERHERSSPLPGKKPPVPKHGWGP 314 PP + P G +PP P G P Sbjct: 219 PPAGKPQGPPPPPQGGRPPRPAQGQQP 245 Score = 35.0 bits (79), Expect = 0.17 Identities = 39/163 (23%), Positives = 53/163 (32%), Gaps = 30/163 (18%) Query: 258 GKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLP--GKKPPVPKHGWGPD 315 G++P ++P P P KP PP ++ P P GK P G Sbjct: 38 GRRPQGGNQPQRPP--------PPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQS 89 Query: 316 RRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSA 375 + +RP PQ + P + +P P S P Sbjct: 90 QGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPP-------------- 135 Query: 376 SLPPYFSQGPSNRPPIRAEGRNF-PLPLPNKPRPPSPAEEENS 417 PP G RPP + ++ P P P KP P P E S Sbjct: 136 --PP---PGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKS 173 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 68.9 bits (167), Expect = 1e-11 Identities = 78/310 (25%), Positives = 101/310 (32%), Gaps = 46/310 (14%) Query: 117 NDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDR 176 N+D E+ + N + +P + PPP + P P P + Sbjct: 20 NEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGK--------PQGPPPQGGNKPQGP 71 Query: 177 PPSGKTPQQPPV----------PPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHK 226 PP GK PQ PP PP +P PPP G PPP + P ++ Sbjct: 72 PPPGK-PQGPPPQGDKSRSPRSPPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNR 128 Query: 227 TAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPP 286 P P + P D+S +P G P ++P P P KP Sbjct: 129 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP--------PPPGKPQ 180 Query: 287 LPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRS 346 PP + P P KP P R Q P PQ P P + Sbjct: 181 GPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKP 240 Query: 347 TKP------SPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPL 400 P P P P G ++ S QSA PP QGP + EG N Sbjct: 241 QGPPPQGGNKPQGPPPPGKPQGPPAQGGSK-SQSARSPPGKPQGPPQQ-----EGNN--- 291 Query: 401 PLPNKPRPPS 410 P P PP+ Sbjct: 292 --PQGPPPPA 299 Score = 63.5 bits (153), Expect = 4e-10 Identities = 64/241 (26%), Positives = 77/241 (31%), Gaps = 42/241 (17%) Query: 177 PPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSID 236 P G PQ PP PP +P PPP G N PPP P Sbjct: 41 PQGGNKPQGPPPPPGKPQG---PPPQGGNKPQGPPP--------------------PGKP 77 Query: 237 RSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHER 296 + P D+S +P G P ++P P P KP PP + Sbjct: 78 QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP--------PPPGKPQGPPPQGGNRP 129 Query: 297 SSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKP------S 350 P P KP P R Q P PQ P P + P Sbjct: 130 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK 189 Query: 351 PMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPS 410 P P P G + + S +S+ PP QGP PP P P P KP+ P Sbjct: 190 PQGPPPPGKPQGPPPQGDKS--RSSQSPPGKPQGP---PPQGGNQPQGPPPPPGKPQGPP 244 Query: 411 P 411 P Sbjct: 245 P 245 Score = 59.3 bits (142), Expect = 8e-09 Identities = 77/300 (25%), Positives = 95/300 (31%), Gaps = 55/300 (18%) Query: 122 GEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGK 181 G+ G + + P PPP D+ S P KP P G Sbjct: 55 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP-PGKPQGPP-------PQGGN 106 Query: 182 TPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEP------SRSRNHKTAKLPAP-- 233 PQ PP PP +P PPP G N PPP + P SRS K P Sbjct: 107 QPQGPPPPPGKPQG---PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 163 Query: 234 ---SIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAG--------RSLGEHLPKI 282 + + PP + P P GKKP P P G RS K Sbjct: 164 QGGNQPQGPPPPPGKPQGP----PPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKP 219 Query: 283 QKPPL---------PPTTERHERSSPLPGKKP---PVPKHGWGPDRRENDEDDVHQRPLP 330 Q PP PP + + P G KP P P GP + + + P Sbjct: 220 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPG 279 Query: 331 QPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPP 390 +P P P P+ NP P + PQ PP G +RPP Sbjct: 280 KPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP-------AGQPQGPPRPP--QGGRPSRPP 330 Score = 40.8 bits (94), Expect = 0.003 Identities = 43/160 (26%), Positives = 51/160 (31%), Gaps = 19/160 (11%) Query: 258 GKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRR 317 G P +KP P P KP PP ++ P P KP P R Sbjct: 38 GPSPQGGNKPQGPP--------PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRS 89 Query: 318 ENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMN------PLPSSHMPGAFSESNSSF 371 Q P PQ P P + P P P P G + + S Sbjct: 90 PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKS- 148 Query: 372 PQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSP 411 +S PP QGP PP P P P KP+ P P Sbjct: 149 -RSPRSPPGKPQGP---PPQGGNQPQGPPPPPGKPQGPPP 184 Score = 36.2 bits (82), Expect = 0.077 Identities = 27/97 (27%), Positives = 35/97 (36%), Gaps = 8/97 (8%) Query: 122 GEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPF----PNSNSMYIDRP 177 G+ G + + P PP ++ P KP N+ P Sbjct: 238 GKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPP 297 Query: 178 PSGKTPQQPPVPPQ-RPMAALPPPPAGRNHSPLPPPQ 213 P+G PQQP PP +P PP GR P PPQ Sbjct: 298 PAGGNPQQPQAPPAGQPQGPPRPPQGGR---PSRPPQ 331 Score = 32.7 bits (73), Expect = 0.85 Identities = 38/155 (24%), Positives = 57/155 (36%), Gaps = 24/155 (15%) Query: 268 SIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKP----PVPKHGWGPDRRENDEDD 323 ++ + ++L E + + + P L + SP G KP P P GP + ++ Sbjct: 12 ALSSAQNLNEDVSQEESPSL--IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQ 69 Query: 324 VHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQ 383 P P + RS P P P + PQ PP Q Sbjct: 70 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG----------GNQPQGPPPPPGKPQ 119 Query: 384 GPSNRPPIRAEGRNFPL--PLPNKPRPPSPAEEEN 416 GP PP +G N P P P KP+ P P +++ Sbjct: 120 GP---PP---QGGNRPQGPPPPGKPQGPPPQGDKS 148 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 67.8 bits (164), Expect = 2e-11 Identities = 86/342 (25%), Positives = 129/342 (37%), Gaps = 52/342 (15%) Query: 131 PNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPP 190 P E +P +++ PPP + LPA P P + +++ RP ++P PP P Sbjct: 444 PEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEA--LHLSRPLE-ESPLSPP-PE 499 Query: 191 QRPMAALPPPPAGR----NHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRS 246 + P++ PPP + SPL PP+ E P P+P+++ PP + S Sbjct: 500 ESPLS--PPPESSPFSPLEESPLSPPE---ESP-----------PSPALETPLSPPPEAS 543 Query: 247 LAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP 306 P + PPF + P P L P PP E SP P + P Sbjct: 544 -------PLS----PPFEESPLSPPPEELPTSPPPEASRLSPPPEE--SPMSPPPEESPM 590 Query: 307 VPKHGWGPDRRENDEDDVHQRPL-PQPALLPMSSNTFPSRSTKP---SPMNPLP--SSHM 360 P P + PL P P P+S SR + P SPM+P P S Sbjct: 591 SP-----PPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMS 645 Query: 361 PGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFP----LPLPNKPRPPSPAEEEN 416 P S P + L P + P + PP + P L P + P SP E++ Sbjct: 646 PPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDS 705 Query: 417 SLNEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNP 458 + S ++ P E+ L + ++ R + P Sbjct: 706 PASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRP 747 Score = 65.1 bits (157), Expect = 2e-10 Identities = 82/306 (26%), Positives = 110/306 (35%), Gaps = 45/306 (14%) Query: 149 PSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPV--PPQRPMAALP------PP 200 PS D L + FP + Y P P QPP+ RP A P PP Sbjct: 2172 PSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPP 2231 Query: 201 PAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKP-----PLDRSLAPFDREPF 255 R+ P P PS N + P ++++P P S + + Sbjct: 2232 GTPRHQPSTPDPFLKPRCPSLD-NLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKE 2290 Query: 256 TLGKKPPFSDKPSIPA--GRSLGEHL-------PKIQKPPLPPTTERHERSSPLPGKKP- 305 LG P P++ S G HL P + K PL P + E SP G +P Sbjct: 2291 ELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQ 2350 Query: 306 -PVPKHGWGPDRRENDE--------DDVHQRPL---PQPALLPMSSNTFPSRSTKPSPMN 353 P P P + + D Q PL PQP P S P RS P + Sbjct: 2351 EPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP-PESCCALPPRSLPSDPFS 2409 Query: 354 PLPSSHMPGAFSESN--------SSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNK 405 +P+S + S+S +F S P + S P +RPP R + R+ PL Sbjct: 2410 RVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKP 2469 Query: 406 PRPPSP 411 PRP P Sbjct: 2470 PRPQPP 2475 Score = 54.3 bits (129), Expect = 3e-07 Identities = 75/290 (25%), Positives = 106/290 (36%), Gaps = 35/290 (12%) Query: 131 PNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPP 190 P +P+E+ P S AL+ + P P + S + P P++ P P Sbjct: 507 PESSPFSPLEESPLSPPEESPPSPALETPLSPP-PEASPLSPPFEESPLSPPPEELPTSP 565 Query: 191 QRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPF 250 + L PPP SP+ PP EE S + ++L P + PP + S P Sbjct: 566 PPEASRLSPPPEE---SPMSPPP---EESPMSPPPEASRLFPPFEESPLSPPPEES--PL 617 Query: 251 DREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLP---GKKPPV 307 P PP D P P P + P PP R SPLP PP Sbjct: 618 SPPPEASRLSPPPEDSPMSP---------PPEESPMSPP--PEVSRLSPLPVVSRLSPPP 666 Query: 308 PKHGWGPDRRENDEDDVHQRPLPQPA-LLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSE 366 + P E+ P P+ + L P ++ S + SP +P P + E Sbjct: 667 EESPLSPPPEESPTS-----PPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLE 721 Query: 367 SNS--SFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEE 414 + P+ L P S+GP P R E + P P +P AEE Sbjct: 722 ESPLLPLPEEPQLCPR-SEGPHLSP--RPEEPHLS-PRPEEPHLSPQAEE 767 Score = 53.5 bits (127), Expect = 5e-07 Identities = 82/331 (24%), Positives = 114/331 (34%), Gaps = 56/331 (16%) Query: 130 SPNEEEEAPVED-DADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKT----PQ 184 SP E + P ++ DA Y + S+ P +P P + + P GK Sbjct: 373 SPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGP----LQCEAKPLGKAGVQLEP 428 Query: 185 QPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLD 244 Q P M LPPP SPL PP P ++ PP Sbjct: 429 QLEAPLNEEMPLLPPP----EESPLSPP--------------------PEESPTSPPPEA 464 Query: 245 RSLAPFDRE------PFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSS 298 L+P E P L P + P P E P P P + E Sbjct: 465 SRLSPPPEELPASPLPEALHLSRPLEESPLSPP----PEESPLSPPPESSPFSPLEESPL 520 Query: 299 PLPGKKPPVPKHGW---GPDRRENDEDDVHQRPL-PQPALLPMSSNTFPSRSTKP---SP 351 P + PP P P + PL P P LP S SR + P SP Sbjct: 521 SPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESP 580 Query: 352 MNPLPSSHMPGAFSESNSSFP--QSASLPPYFSQGPSNRPP----IRAEGRNFPLPLPNK 405 M+P P E++ FP + + L P + P + PP + + P+ P + Sbjct: 581 MSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPE 640 Query: 406 PRPPSPAEEENSLNEEWYVSYITRPEAEAAL 436 P SP E + L+ VS ++ P E+ L Sbjct: 641 ESPMSPPPEVSRLSPLPVVSRLSPPPEESPL 671 Score = 48.9 bits (115), Expect = 1e-05 Identities = 82/325 (25%), Positives = 123/325 (37%), Gaps = 52/325 (16%) Query: 130 SPNEEEE--APVEDDADYEPPPSNDEEALQNS--ILPAKPFPNSNSMYIDRPPSGKTPQQ 185 SP EE +PV ++ P P + Q+ L +P + S +++PP P++ Sbjct: 807 SPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEK 866 Query: 186 PPVPPQRPMA----ALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPS---IDRS 238 PP P + A L PPP + SPL EP+ S + P P + S Sbjct: 867 PPEEPGQCPAPEELPLFPPPGEPSLSPL------LGEPALSEPGEPPLSPLPEELPLSPS 920 Query: 239 TKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGE-----------------HLPK 281 +P L L P D P L P + PA LGE P Sbjct: 921 GEPSLSPQLMPPDPLPPPLS---PIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPI 977 Query: 282 IQKPPLPPTTERHERSSPLPGK-KPPVPKHGWGPDRRENDEDDVHQ-RPLPQPALLPMSS 339 ++ P PP P+P PP P GP E Q PL Q +L+P Sbjct: 978 LETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVP--Q 1035 Query: 340 NTFPSRSTK-------PSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIR 392 N+ PS+ + PSP++P+ +E + + S P + PS P+ Sbjct: 1036 NSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLP 1095 Query: 393 AEGRNFPLPLPNKPRPPSPAEEENS 417 + + P P+ P+PA ++ S Sbjct: 1096 SPMGDLSCPAPS----PAPALDDFS 1116 Score = 40.8 bits (94), Expect = 0.003 Identities = 51/182 (28%), Positives = 73/182 (40%), Gaps = 25/182 (13%) Query: 166 FPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNH 225 FP + + +G PQ PP P P A P G H P PPP ++ +EP R Sbjct: 4266 FPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVH-PTPPP-SSPQEPKR---- 4319 Query: 226 KTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPS---IPAGRSLGEHLPKI 282 ++LP+P S++ P + L P P T + P + P PA L + L Sbjct: 4320 -PSQLPSP----SSQLPTEAQLPP--THPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSK 4372 Query: 283 QKPPLPP-----TTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPM 337 P P T++ E+SS +PG V G E + + Q P +P L Sbjct: 4373 GLGPWDPPDNLAETQKPEQSSLVPGHLDQVN----GQVVPEASQLSIKQEPREEPCALGA 4428 Query: 338 SS 339 S Sbjct: 4429 QS 4430 Score = 35.8 bits (81), Expect = 0.10 Identities = 29/106 (27%), Positives = 40/106 (37%), Gaps = 20/106 (18%) Query: 204 RNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPF 263 + SP P P T H N +L AP + + PP LAP P T P Sbjct: 4880 KQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPP--SPLAPSPASPPT----EPL 4933 Query: 264 SDKPSIPAGRSLGEHLPKIQKPPLP---PTTERHERSSPLPGKKPP 306 + P+ P + +PP+P P E + P P +PP Sbjct: 4934 VELPTEP-----------LAEPPVPSPLPLASSPESARPKPRARPP 4968 Score = 35.4 bits (80), Expect = 0.13 Identities = 35/118 (29%), Positives = 44/118 (37%), Gaps = 19/118 (16%) Query: 288 PPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQ-PALLPMSSNTF---- 342 PP E ++SPL G P+ G P + ++ P PQ P LP Sbjct: 4241 PPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGP 4300 Query: 343 ---PSRSTKP--SPMNPLPSSHMPGAFSESNSSFPQSASLPPYF-----SQGPSNRPP 390 P T P SP P S +P +S P A LPP QGP+ PP Sbjct: 4301 VLGPVHPTPPPSSPQEPKRPSQLP----SPSSQLPTEAQLPPTHPGTPKPQGPTLEPP 4354 Score = 31.6 bits (70), Expect = 1.9 Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 5/66 (7%) Query: 177 PPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSID 236 PPS P P PP P+ LP P P+P P P +R A+ P D Sbjct: 4917 PPSPLAPS-PASPPTEPLVELPTEPLA--EPPVPSPLPLASSPESARPKPRARPPEEGED 4973 Query: 237 RSTKPP 242 ++PP Sbjct: 4974 --SRPP 4977 Score = 29.6 bits (65), Expect = 7.2 Identities = 69/268 (25%), Positives = 94/268 (35%), Gaps = 59/268 (22%) Query: 147 PPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPM------------ 194 P P + E + + P P+ S RP S + P P P RP Sbjct: 2427 PRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQS-RDPFAPLHKPPRPQPPEVAFKAGSLA 2485 Query: 195 ----------AALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKT-AKLPAPSIDRSTKPPL 243 AALP PAG H+ +P Q P+ R+ T A + PS R T P Sbjct: 2486 HTSLGAGGFPAALPAGPAGELHAKVPSGQ----PPNFVRSPGTGAFVGTPSPMRFTFPQA 2541 Query: 244 --DRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPL- 300 + SL P +P G PP G +LG+ P+ + T H SPL Sbjct: 2542 VGEPSLKPPVPQP---GLPPPHGINSHFGPGPTLGK--PQSTNYTV-ATGNFHPSGSPLG 2595 Query: 301 PGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPA---LLPMSSNTFPSRSTKPSPM----- 352 P +G P R + LP PA LP S+ RS SP+ Sbjct: 2596 PSSGSTGESYGLSPLRPPS--------VLPPPAPDGSLPYLSHGASQRSGITSPVEKRED 2647 Query: 353 ------NPLPSSHMPGAFSESNSSFPQS 374 + L ++ +PG S Q+ Sbjct: 2648 PGTGMGSSLATAELPGTQDPGMSGLSQT 2675 Score = 29.6 bits (65), Expect = 7.2 Identities = 22/79 (27%), Positives = 29/79 (36%), Gaps = 19/79 (24%) Query: 131 PNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPP 190 P PV PPPS+ +E + S LP+ PS + P + +PP Sbjct: 4293 PGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPS--------------PSSQLPTEAQLPP 4338 Query: 191 QRPMAALP-----PPPAGR 204 P P PP GR Sbjct: 4339 THPGTPKPQGPTLEPPPGR 4357 Score = 29.3 bits (64), Expect = 9.4 Identities = 36/126 (28%), Positives = 43/126 (34%), Gaps = 20/126 (15%) Query: 297 SSPLPGKKPPVPKHGWGP----DRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPM 352 S+ LPG PVP GP + R N + + P P P F S P + Sbjct: 2858 STRLPGPGEPVPGPA-GPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRL 2916 Query: 353 NP-----LPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPR 407 P L S +P PQ S PP S P +G P L R Sbjct: 2917 APEGLRGLAVSGLP----------PQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNR 2966 Query: 408 PPSPAE 413 PPS E Sbjct: 2967 PPSSTE 2972 >gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] Length = 2063 Score = 67.8 bits (164), Expect = 2e-11 Identities = 79/326 (24%), Positives = 118/326 (36%), Gaps = 57/326 (17%) Query: 141 DDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPP-------VPPQRP 193 ++AD P P L NS F N Y +P + QQ P PP +P Sbjct: 941 EEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQP 1000 Query: 194 MAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDRE 253 P P + P PP Q ++ + + L +S + P+ +++ P R Sbjct: 1001 PQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHP-PRG 1059 Query: 254 PFTL-GKKPPFSDKPSIPA-----GRSLGEHLPKIQKPPLPPTTERHERS-------SPL 300 P ++ P S+P G + P Q+ P+P T S SP Sbjct: 1060 PLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQ 1119 Query: 301 PGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPS---------- 350 P+ + P+ ++ V P P+ + + N KP Sbjct: 1120 NPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGA 1179 Query: 351 -----PMNPLPSS---HMPGAFSESNSSFPQS---ASLPPYFSQGPSNRPP--------I 391 P+N LPSS H P + + +S P++ AS PY+ Q P+NRPP + Sbjct: 1180 TPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISL 1239 Query: 392 RAEGRN------FPLPLPNKPRPPSP 411 E N FP P N P PP P Sbjct: 1240 SPERLNASIAGLFP-PQINIPLPPRP 1264 Score = 42.7 bits (99), Expect = 8e-04 Identities = 52/227 (22%), Positives = 76/227 (33%), Gaps = 43/227 (18%) Query: 178 PSGKTPQQPPVPP---QRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPS 234 P P Q PVPP Q P AL PPPA Q + + ++ K A LP P Sbjct: 304 PQFTAPTQVPVPPGWNQLPSGALQPPPA----------QGSLGTMTANQGWKKAPLPGPM 353 Query: 235 IDR-STKPPLDRSLAP-FDREPFTLGKKPPFSDKPSIPA----GRSLGEHLPKIQKPP-- 286 + +P L P P+ G + + P G+ + +Q P Sbjct: 354 QQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSR 413 Query: 287 LPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRS 346 +P ++ ++ P P + G PA P + T Sbjct: 414 VPTPLQQPHLTNKSPASSPSSFQQG-------------------SPASSPTVNQTQQQMG 454 Query: 347 TKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYF---SQGPSNRPP 390 +P NPLP S + Q ++PP F Q P N+ P Sbjct: 455 PRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGP 501 Score = 31.6 bits (70), Expect = 1.9 Identities = 33/136 (24%), Positives = 55/136 (40%), Gaps = 14/136 (10%) Query: 157 QNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNH 216 Q S +PA P ++ + PPS +P ++ P PP + SP P QT Sbjct: 1674 QPSTIPAAPLTTNSGLM---PPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGR 1730 Query: 217 EEPSRSRNHKTAKLPAPSIDRS----TKPPLD--RSLAPFDREPFTLGKKPPFSDKPSIP 270 SR +LP+P S + PP+ + L P + P + +D+ ++P Sbjct: 1731 PLVLSSR-ATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASP----QVNTSADQNTLP 1785 Query: 271 AGRSLGEHLPKIQKPP 286 + +S P + P Sbjct: 1786 SSQSTTMVSPLLTNSP 1801 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 67.0 bits (162), Expect = 4e-11 Identities = 83/315 (26%), Positives = 107/315 (33%), Gaps = 54/315 (17%) Query: 131 PNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPP 190 P+ P E + PP AL + L P P + + PP PQ PP Sbjct: 573 PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLAT--PP----PQAPPXLA 626 Query: 191 QRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPF 250 P+ A P PPA SPL P + P PS PP+ +P Sbjct: 627 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS------PPVQAPFSPP 680 Query: 251 DREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP---V 307 P + PP PS+ A P +Q PP PP + S+ P + PP Sbjct: 681 ASPPVSPSATPPSQAPPSLAA--------PPLQVPPSPPASPPMSPSATPPPQAPPPLAA 732 Query: 308 PKHGWGPDRRENDEDDVHQRPLPQ----------------PALLPMSSNTFPSRSTKPS- 350 P P + P P+ PA LPMS P P+ Sbjct: 733 PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792 Query: 351 ---PMNPLPSSHMPGAFSESNSSFPQSASLP--PYFSQGPSNRPPIRAEGRNFPLPLPNK 405 P+ LPS P A + F SASLP P + P P + A P P Sbjct: 793 ATPPLQALPS---PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 849 Query: 406 P------RPPSPAEE 414 P RPP+P + Sbjct: 850 PTLQAPRRPPTPGPD 864 Score = 56.2 bits (134), Expect = 7e-08 Identities = 77/299 (25%), Positives = 106/299 (35%), Gaps = 37/299 (12%) Query: 131 PNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPP 190 P E ++ + + PP S L+N A P + S + P P P P Sbjct: 510 PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL 569 Query: 191 QRPMAAL-PPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDR---- 245 Q P + L PPP + PPPQ P + LP+P + PP Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQA----PPALASPPLQGLPSPPLSPLATPPPQAPPXL 625 Query: 246 SLAPFDREPFTLGKKPPFSD--KPSIPAGRSLGEHL----------PKIQKPPLPPTTER 293 +L P P + PP S PS A +L HL P +Q P PP + Sbjct: 626 ALPPLQAPP-SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 684 Query: 294 HERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMS-SNTFPSRSTKPSPM 352 S+ P + PP + Q P PA PMS S T P ++ P Sbjct: 685 VSPSATPPSQAPP------------SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 732 Query: 353 NPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSP 411 PL P A + S +PP + P PP + + P+ KP P +P Sbjct: 733 PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP--SPPASLPMSPLAKPPPQAP 789 Score = 50.8 bits (120), Expect = 3e-06 Identities = 75/302 (24%), Positives = 106/302 (35%), Gaps = 53/302 (17%) Query: 162 PAKPF-PNSNSMYIDRPPSGKTPQQPPVPPQRPMAALP---PPPAGRNHSPLPPPQTNHE 217 PA P P + RPP P++ P P+++ P P P+G P+PPP N Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD-NAA 324 Query: 218 EPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFT-LGKKPPFSDKPSIPAGRSL- 275 P + + L P P SL P T + PP P + A SL Sbjct: 325 TPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQ 384 Query: 276 ---------GEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGW-------------G 313 P +Q PP P + ++ L G H + Sbjct: 385 TIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL-GSPTLQATHSFLTMSPRQTQASLTS 443 Query: 314 PDRRENDEDDVH--QRPLPQPALLPMSSNTFPSRSTKPSPMNPLP-------SSHMPGAF 364 P R + D Q PL PA P+ ++ P+ S SP+ P +SH P A Sbjct: 444 PSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAP 503 Query: 365 SESNSSFP---QSASLPPYFSQGPSN--RPPIR---------AEGRNFPLPLPNKPRPPS 410 S P QS+ PP P++ PP+ + + PL P+ PP Sbjct: 504 LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPC 563 Query: 411 PA 412 PA Sbjct: 564 PA 565 Score = 47.8 bits (112), Expect = 3e-05 Identities = 78/308 (25%), Positives = 101/308 (32%), Gaps = 52/308 (16%) Query: 130 SPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVP 189 SP+ + PV PPP N L ++ P+ P + P + + Q P P Sbjct: 308 SPSGTKARPV-------PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360 Query: 190 PQRPMAALPP----PP--AGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRST---K 240 P P + PP PP A + +PP Q H S S + L S+ +T Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420 Query: 241 PPL--------------DRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHL-PKIQKP 285 P L SL R T PP S+PA L L P + Sbjct: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480 Query: 286 PLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPL-PQPALLPMSSNTFPS 344 P T + S L P P + PL Q +L P S T P+ Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPL------------SSLIMPPLETQSSLAPPSLQTPPA 528 Query: 345 RSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPN 404 T P P+ LPS P + S PP + P PP PL P Sbjct: 529 SLTTP-PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP-------SPLTTPP 580 Query: 405 KPRPPSPA 412 P S A Sbjct: 581 PETPSSIA 588 Score = 38.9 bits (89), Expect = 0.012 Identities = 45/185 (24%), Positives = 65/185 (35%), Gaps = 34/185 (18%) Query: 148 PPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVP--------PQRPMAALPP 199 PP L +L P P ++ P+ + P++PP P P+ +A P Sbjct: 827 PPPQAPPVLAAPLLQVPPSPPAS-------PTLQAPRRPPTPGPDTSVSGPRLTLALAPG 879 Query: 200 PPAGRNHSPLP----PPQTNHEEPSRSRNHKTAKLPA-PSIDRSTKPPLDRSLAPFDREP 254 PP + SP P H + S + + P + PP D LA Sbjct: 880 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 939 Query: 255 FTLGKKPP--FSDKPSIP------AGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP 306 ++ G PP F P P G + L I + TE E ++P PG P Sbjct: 940 WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE------TEGPESATPAPGALDP 993 Query: 307 VPKHG 311 P G Sbjct: 994 GPSPG 998 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 64.7 bits (156), Expect = 2e-10 Identities = 77/355 (21%), Positives = 118/355 (33%), Gaps = 29/355 (8%) Query: 73 NKNEERRSIFTRKPQVPRF---PEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYE 129 NK I T KP PR P S E + E+ ++ DG + Sbjct: 110 NKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK 169 Query: 130 SPNEEEEAPVEDDADYEPPPSND------EEALQNSILPAKPFPNSNSMYIDRPPSGKTP 183 + + +E +E + + P++ +A + PA P + + P+ TP Sbjct: 170 TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP 229 Query: 184 QQPPVP-----PQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRS 238 ++P P P P +P P T +EP+ + T K PAP+ + Sbjct: 230 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT----TPKEPAPTTTKE 285 Query: 239 TKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSS 298 P +S +EP K P P PA + E P K P P T E + Sbjct: 286 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE----PA 341 Query: 299 PLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSS 358 P K+P P + + P P P + T T P P + Sbjct: 342 PTTPKEP-------APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 394 Query: 359 HMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAE 413 P E + +SA P + + P + P KP P +P E Sbjct: 395 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 449 Score = 60.8 bits (146), Expect = 3e-09 Identities = 66/294 (22%), Positives = 99/294 (33%), Gaps = 36/294 (12%) Query: 146 EPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRN 205 EP P+ + A P +P P + + P+ TP++P P P P Sbjct: 246 EPAPTTTKSA---PTTPKEPAPTTT-----KEPAPTTPKEPA-----PTTTKEPAPTTTK 292 Query: 206 HSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSD 265 +P P + P + T K PAP+ + P + AP +EP K P Sbjct: 293 SAPTTPKEPAPTTPKKPAP-TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 351 Query: 266 KPSIPAGRSLGEHLPKIQKPPLPPTTERHE------------RSSPLPGKKPPVPKHGWG 313 P PA + E P K P P TT+ +S+P K+P Sbjct: 352 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 411 Query: 314 PDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQ 373 P + + P P P + T P + +P P P++ A + + P Sbjct: 412 PTTPKEPSPTTTKEPAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 469 Query: 374 SASLPPYFSQGPSNRPPIRAEGRNFPLP------LPNKPRPPSPAEEENSLNEE 421 + P P P + P P KP P +P E + EE Sbjct: 470 TPKEPA--PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 521 Score = 59.7 bits (143), Expect = 6e-09 Identities = 78/354 (22%), Positives = 119/354 (33%), Gaps = 53/354 (14%) Query: 130 SPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQP-PV 188 +P + AP EP P+ +E PA P + + P+ TP++P P Sbjct: 404 APTTTKSAPTTPK---EPSPTTTKE-------PAPTTPKEPAPTTPKKPAPTTPKEPAPT 453 Query: 189 PPQRPMAAL---PPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDR 245 P+ P P P + +P P +T P + KL AP+ P Sbjct: 454 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL-APTTPEKPAPTTPE 512 Query: 246 SLAPFD-REPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKK 304 LAP EP + P P A + E P K P P T + E + P + Sbjct: 513 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--EPAPTTPKET 570 Query: 305 PPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSS-----------------NTFPSRST 347 P G P + ++P P+ L P ++ T P+ Sbjct: 571 APTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 629 Query: 348 KPSPMNP------LPSSHMPGAFSESNSSFPQSAS---LPPYFSQGP----SNRPPIRAE 394 +P+P P P P E + P+ + L P ++GP S++P Sbjct: 630 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 689 Query: 395 GRNFPL----PLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALRKINQDGT 444 P P P P+ P+P E VS T + + K + T Sbjct: 690 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 743 Score = 58.9 bits (141), Expect = 1e-08 Identities = 71/280 (25%), Positives = 96/280 (34%), Gaps = 52/280 (18%) Query: 162 PAKPFPNSNSMYIDRPPSGKTPQQPPVP-PQRPMAALPPPPAGRNHSPLPPPQTNHEEPS 220 P KP P + P TP P P P P AA P ++P P T +EP+ Sbjct: 503 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-------NTPKEPAPTTPKEPA 555 Query: 221 RSRNHKTAKLPAPSIDRSTKPPLDRSLAPFD-REPF-TLGKKP------------PFS-- 264 + T K PAP+ + T P + AP +EP T KKP P S Sbjct: 556 PT----TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 611 Query: 265 -DKPSIPAGRSLGEHLPKIQKPPLP----PTTERHERSSPLPGKKPPVPKHGW------- 312 DKP+ + PK P P PTT + + L P PK Sbjct: 612 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 671 Query: 313 ---GPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNS 369 GP +D+ P P ++ T P +P P P++ + S Sbjct: 672 TTKGPTSTTSDK--------PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 723 Query: 370 SFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPP 409 S P + P + P P P L N P+ P Sbjct: 724 STPTTTKEPTTIHKSPDESTP-ELSAEPTPKALENSPKEP 762 Score = 38.9 bits (89), Expect = 0.012 Identities = 43/203 (21%), Positives = 69/203 (33%), Gaps = 38/203 (18%) Query: 162 PAKPFPNSNSMYIDRPPSGKTPQQP---------PVPPQRPMAALPPPPAG--------- 203 P KP P + + P+ T +P P P+ P P PA Sbjct: 591 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 650 Query: 204 --RNHSPLPPPQTNHEE----PSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDRE---P 254 + +P P + +E ++ T+ PAP+ + T P + AP + P Sbjct: 651 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 710 Query: 255 FTLGKKPPFSDKPSIPA--------GRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP 306 T PP + + S P +S E P++ P P E + +P K P Sbjct: 711 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP 770 Query: 307 VPKHGWGPDRRENDEDDVHQRPL 329 P+ +D +R L Sbjct: 771 AATK---PEMTTTAKDKTTERDL 790 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 64.7 bits (156), Expect = 2e-10 Identities = 77/355 (21%), Positives = 118/355 (33%), Gaps = 29/355 (8%) Query: 73 NKNEERRSIFTRKPQVPRF---PEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYE 129 NK I T KP PR P S E + E+ ++ DG + Sbjct: 151 NKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK 210 Query: 130 SPNEEEEAPVEDDADYEPPPSND------EEALQNSILPAKPFPNSNSMYIDRPPSGKTP 183 + + +E +E + + P++ +A + PA P + + P+ TP Sbjct: 211 TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP 270 Query: 184 QQPPVP-----PQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRS 238 ++P P P P +P P T +EP+ + T K PAP+ + Sbjct: 271 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT----TPKEPAPTTTKE 326 Query: 239 TKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSS 298 P +S +EP K P P PA + E P K P P T E + Sbjct: 327 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE----PA 382 Query: 299 PLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSS 358 P K+P P + + P P P + T T P P + Sbjct: 383 PTTPKEP-------APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 435 Query: 359 HMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAE 413 P E + +SA P + + P + P KP P +P E Sbjct: 436 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 490 Score = 60.8 bits (146), Expect = 3e-09 Identities = 66/294 (22%), Positives = 99/294 (33%), Gaps = 36/294 (12%) Query: 146 EPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRN 205 EP P+ + A P +P P + + P+ TP++P P P P Sbjct: 287 EPAPTTTKSA---PTTPKEPAPTTT-----KEPAPTTPKEPA-----PTTTKEPAPTTTK 333 Query: 206 HSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSD 265 +P P + P + T K PAP+ + P + AP +EP K P Sbjct: 334 SAPTTPKEPAPTTPKKPAP-TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 392 Query: 266 KPSIPAGRSLGEHLPKIQKPPLPPTTERHE------------RSSPLPGKKPPVPKHGWG 313 P PA + E P K P P TT+ +S+P K+P Sbjct: 393 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 452 Query: 314 PDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQ 373 P + + P P P + T P + +P P P++ A + + P Sbjct: 453 PTTPKEPSPTTTKEPAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 510 Query: 374 SASLPPYFSQGPSNRPPIRAEGRNFPLP------LPNKPRPPSPAEEENSLNEE 421 + P P P + P P KP P +P E + EE Sbjct: 511 TPKEPA--PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 562 Score = 59.7 bits (143), Expect = 6e-09 Identities = 78/354 (22%), Positives = 119/354 (33%), Gaps = 53/354 (14%) Query: 130 SPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQP-PV 188 +P + AP EP P+ +E PA P + + P+ TP++P P Sbjct: 445 APTTTKSAPTTPK---EPSPTTTKE-------PAPTTPKEPAPTTPKKPAPTTPKEPAPT 494 Query: 189 PPQRPMAAL---PPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDR 245 P+ P P P + +P P +T P + KL AP+ P Sbjct: 495 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL-APTTPEKPAPTTPE 553 Query: 246 SLAPFD-REPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKK 304 LAP EP + P P A + E P K P P T + E + P + Sbjct: 554 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--EPAPTTPKET 611 Query: 305 PPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSS-----------------NTFPSRST 347 P G P + ++P P+ L P ++ T P+ Sbjct: 612 APTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 670 Query: 348 KPSPMNP------LPSSHMPGAFSESNSSFPQSAS---LPPYFSQGP----SNRPPIRAE 394 +P+P P P P E + P+ + L P ++GP S++P Sbjct: 671 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 730 Query: 395 GRNFPL----PLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALRKINQDGT 444 P P P P+ P+P E VS T + + K + T Sbjct: 731 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 784 Score = 58.9 bits (141), Expect = 1e-08 Identities = 71/280 (25%), Positives = 96/280 (34%), Gaps = 52/280 (18%) Query: 162 PAKPFPNSNSMYIDRPPSGKTPQQPPVP-PQRPMAALPPPPAGRNHSPLPPPQTNHEEPS 220 P KP P + P TP P P P P AA P ++P P T +EP+ Sbjct: 544 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-------NTPKEPAPTTPKEPA 596 Query: 221 RSRNHKTAKLPAPSIDRSTKPPLDRSLAPFD-REPF-TLGKKP------------PFS-- 264 + T K PAP+ + T P + AP +EP T KKP P S Sbjct: 597 PT----TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 652 Query: 265 -DKPSIPAGRSLGEHLPKIQKPPLP----PTTERHERSSPLPGKKPPVPKHGW------- 312 DKP+ + PK P P PTT + + L P PK Sbjct: 653 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 712 Query: 313 ---GPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNS 369 GP +D+ P P ++ T P +P P P++ + S Sbjct: 713 TTKGPTSTTSDK--------PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 764 Query: 370 SFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPP 409 S P + P + P P P L N P+ P Sbjct: 765 STPTTTKEPTTIHKSPDESTP-ELSAEPTPKALENSPKEP 803 Score = 38.9 bits (89), Expect = 0.012 Identities = 43/203 (21%), Positives = 69/203 (33%), Gaps = 38/203 (18%) Query: 162 PAKPFPNSNSMYIDRPPSGKTPQQP---------PVPPQRPMAALPPPPAG--------- 203 P KP P + + P+ T +P P P+ P P PA Sbjct: 632 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 691 Query: 204 --RNHSPLPPPQTNHEE----PSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDRE---P 254 + +P P + +E ++ T+ PAP+ + T P + AP + P Sbjct: 692 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 751 Query: 255 FTLGKKPPFSDKPSIPA--------GRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP 306 T PP + + S P +S E P++ P P E + +P K P Sbjct: 752 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP 811 Query: 307 VPKHGWGPDRRENDEDDVHQRPL 329 P+ +D +R L Sbjct: 812 AATK---PEMTTTAKDKTTERDL 831 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 64.7 bits (156), Expect = 2e-10 Identities = 77/355 (21%), Positives = 118/355 (33%), Gaps = 29/355 (8%) Query: 73 NKNEERRSIFTRKPQVPRF---PEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYE 129 NK I T KP PR P S E + E+ ++ DG + Sbjct: 203 NKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK 262 Query: 130 SPNEEEEAPVEDDADYEPPPSND------EEALQNSILPAKPFPNSNSMYIDRPPSGKTP 183 + + +E +E + + P++ +A + PA P + + P+ TP Sbjct: 263 TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP 322 Query: 184 QQPPVP-----PQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRS 238 ++P P P P +P P T +EP+ + T K PAP+ + Sbjct: 323 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT----TPKEPAPTTTKE 378 Query: 239 TKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSS 298 P +S +EP K P P PA + E P K P P T E + Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE----PA 434 Query: 299 PLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSS 358 P K+P P + + P P P + T T P P + Sbjct: 435 PTTPKEP-------APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 487 Query: 359 HMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAE 413 P E + +SA P + + P + P KP P +P E Sbjct: 488 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 542 Score = 60.8 bits (146), Expect = 3e-09 Identities = 66/294 (22%), Positives = 99/294 (33%), Gaps = 36/294 (12%) Query: 146 EPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRN 205 EP P+ + A P +P P + + P+ TP++P P P P Sbjct: 339 EPAPTTTKSA---PTTPKEPAPTTT-----KEPAPTTPKEPA-----PTTTKEPAPTTTK 385 Query: 206 HSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSD 265 +P P + P + T K PAP+ + P + AP +EP K P Sbjct: 386 SAPTTPKEPAPTTPKKPAP-TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 444 Query: 266 KPSIPAGRSLGEHLPKIQKPPLPPTTERHE------------RSSPLPGKKPPVPKHGWG 313 P PA + E P K P P TT+ +S+P K+P Sbjct: 445 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 504 Query: 314 PDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQ 373 P + + P P P + T P + +P P P++ A + + P Sbjct: 505 PTTPKEPSPTTTKEPAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 562 Query: 374 SASLPPYFSQGPSNRPPIRAEGRNFPLP------LPNKPRPPSPAEEENSLNEE 421 + P P P + P P KP P +P E + EE Sbjct: 563 TPKEPA--PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 614 Score = 59.7 bits (143), Expect = 6e-09 Identities = 78/354 (22%), Positives = 119/354 (33%), Gaps = 53/354 (14%) Query: 130 SPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQP-PV 188 +P + AP EP P+ +E PA P + + P+ TP++P P Sbjct: 497 APTTTKSAPTTPK---EPSPTTTKE-------PAPTTPKEPAPTTPKKPAPTTPKEPAPT 546 Query: 189 PPQRPMAAL---PPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDR 245 P+ P P P + +P P +T P + KL AP+ P Sbjct: 547 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL-APTTPEKPAPTTPE 605 Query: 246 SLAPFD-REPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKK 304 LAP EP + P P A + E P K P P T + E + P + Sbjct: 606 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--EPAPTTPKET 663 Query: 305 PPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSS-----------------NTFPSRST 347 P G P + ++P P+ L P ++ T P+ Sbjct: 664 APTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 722 Query: 348 KPSPMNP------LPSSHMPGAFSESNSSFPQSAS---LPPYFSQGP----SNRPPIRAE 394 +P+P P P P E + P+ + L P ++GP S++P Sbjct: 723 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 782 Query: 395 GRNFPL----PLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALRKINQDGT 444 P P P P+ P+P E VS T + + K + T Sbjct: 783 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 836 Score = 58.9 bits (141), Expect = 1e-08 Identities = 71/280 (25%), Positives = 96/280 (34%), Gaps = 52/280 (18%) Query: 162 PAKPFPNSNSMYIDRPPSGKTPQQPPVP-PQRPMAALPPPPAGRNHSPLPPPQTNHEEPS 220 P KP P + P TP P P P P AA P ++P P T +EP+ Sbjct: 596 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-------NTPKEPAPTTPKEPA 648 Query: 221 RSRNHKTAKLPAPSIDRSTKPPLDRSLAPFD-REPF-TLGKKP------------PFS-- 264 + T K PAP+ + T P + AP +EP T KKP P S Sbjct: 649 PT----TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 704 Query: 265 -DKPSIPAGRSLGEHLPKIQKPPLP----PTTERHERSSPLPGKKPPVPKHGW------- 312 DKP+ + PK P P PTT + + L P PK Sbjct: 705 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 764 Query: 313 ---GPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNS 369 GP +D+ P P ++ T P +P P P++ + S Sbjct: 765 TTKGPTSTTSDK--------PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 816 Query: 370 SFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPP 409 S P + P + P P P L N P+ P Sbjct: 817 STPTTTKEPTTIHKSPDESTP-ELSAEPTPKALENSPKEP 855 Score = 38.9 bits (89), Expect = 0.012 Identities = 43/203 (21%), Positives = 69/203 (33%), Gaps = 38/203 (18%) Query: 162 PAKPFPNSNSMYIDRPPSGKTPQQP---------PVPPQRPMAALPPPPAG--------- 203 P KP P + + P+ T +P P P+ P P PA Sbjct: 684 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 743 Query: 204 --RNHSPLPPPQTNHEE----PSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDRE---P 254 + +P P + +E ++ T+ PAP+ + T P + AP + P Sbjct: 744 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 803 Query: 255 FTLGKKPPFSDKPSIPA--------GRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP 306 T PP + + S P +S E P++ P P E + +P K P Sbjct: 804 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP 863 Query: 307 VPKHGWGPDRRENDEDDVHQRPL 329 P+ +D +R L Sbjct: 864 AATK---PEMTTTAKDKTTERDL 883 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 64.7 bits (156), Expect = 2e-10 Identities = 77/355 (21%), Positives = 118/355 (33%), Gaps = 29/355 (8%) Query: 73 NKNEERRSIFTRKPQVPRF---PEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYE 129 NK I T KP PR P S E + E+ ++ DG + Sbjct: 244 NKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK 303 Query: 130 SPNEEEEAPVEDDADYEPPPSND------EEALQNSILPAKPFPNSNSMYIDRPPSGKTP 183 + + +E +E + + P++ +A + PA P + + P+ TP Sbjct: 304 TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP 363 Query: 184 QQPPVP-----PQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRS 238 ++P P P P +P P T +EP+ + T K PAP+ + Sbjct: 364 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT----TPKEPAPTTTKE 419 Query: 239 TKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSS 298 P +S +EP K P P PA + E P K P P T E + Sbjct: 420 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE----PA 475 Query: 299 PLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSS 358 P K+P P + + P P P + T T P P + Sbjct: 476 PTTPKEP-------APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 528 Query: 359 HMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAE 413 P E + +SA P + + P + P KP P +P E Sbjct: 529 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 583 Score = 60.8 bits (146), Expect = 3e-09 Identities = 66/294 (22%), Positives = 99/294 (33%), Gaps = 36/294 (12%) Query: 146 EPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRN 205 EP P+ + A P +P P + + P+ TP++P P P P Sbjct: 380 EPAPTTTKSA---PTTPKEPAPTTT-----KEPAPTTPKEPA-----PTTTKEPAPTTTK 426 Query: 206 HSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSD 265 +P P + P + T K PAP+ + P + AP +EP K P Sbjct: 427 SAPTTPKEPAPTTPKKPAP-TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 485 Query: 266 KPSIPAGRSLGEHLPKIQKPPLPPTTERHE------------RSSPLPGKKPPVPKHGWG 313 P PA + E P K P P TT+ +S+P K+P Sbjct: 486 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 545 Query: 314 PDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQ 373 P + + P P P + T P + +P P P++ A + + P Sbjct: 546 PTTPKEPSPTTTKEPAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 603 Query: 374 SASLPPYFSQGPSNRPPIRAEGRNFPLP------LPNKPRPPSPAEEENSLNEE 421 + P P P + P P KP P +P E + EE Sbjct: 604 TPKEPA--PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 655 Score = 59.7 bits (143), Expect = 6e-09 Identities = 78/354 (22%), Positives = 119/354 (33%), Gaps = 53/354 (14%) Query: 130 SPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQP-PV 188 +P + AP EP P+ +E PA P + + P+ TP++P P Sbjct: 538 APTTTKSAPTTPK---EPSPTTTKE-------PAPTTPKEPAPTTPKKPAPTTPKEPAPT 587 Query: 189 PPQRPMAAL---PPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDR 245 P+ P P P + +P P +T P + KL AP+ P Sbjct: 588 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL-APTTPEKPAPTTPE 646 Query: 246 SLAPFD-REPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKK 304 LAP EP + P P A + E P K P P T + E + P + Sbjct: 647 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--EPAPTTPKET 704 Query: 305 PPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSS-----------------NTFPSRST 347 P G P + ++P P+ L P ++ T P+ Sbjct: 705 APTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 763 Query: 348 KPSPMNP------LPSSHMPGAFSESNSSFPQSAS---LPPYFSQGP----SNRPPIRAE 394 +P+P P P P E + P+ + L P ++GP S++P Sbjct: 764 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 823 Query: 395 GRNFPL----PLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALRKINQDGT 444 P P P P+ P+P E VS T + + K + T Sbjct: 824 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 877 Score = 58.9 bits (141), Expect = 1e-08 Identities = 71/280 (25%), Positives = 96/280 (34%), Gaps = 52/280 (18%) Query: 162 PAKPFPNSNSMYIDRPPSGKTPQQPPVP-PQRPMAALPPPPAGRNHSPLPPPQTNHEEPS 220 P KP P + P TP P P P P AA P ++P P T +EP+ Sbjct: 637 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-------NTPKEPAPTTPKEPA 689 Query: 221 RSRNHKTAKLPAPSIDRSTKPPLDRSLAPFD-REPF-TLGKKP------------PFS-- 264 + T K PAP+ + T P + AP +EP T KKP P S Sbjct: 690 PT----TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 745 Query: 265 -DKPSIPAGRSLGEHLPKIQKPPLP----PTTERHERSSPLPGKKPPVPKHGW------- 312 DKP+ + PK P P PTT + + L P PK Sbjct: 746 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 805 Query: 313 ---GPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNS 369 GP +D+ P P ++ T P +P P P++ + S Sbjct: 806 TTKGPTSTTSDK--------PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 857 Query: 370 SFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPP 409 S P + P + P P P L N P+ P Sbjct: 858 STPTTTKEPTTIHKSPDESTP-ELSAEPTPKALENSPKEP 896 Score = 38.9 bits (89), Expect = 0.012 Identities = 43/203 (21%), Positives = 69/203 (33%), Gaps = 38/203 (18%) Query: 162 PAKPFPNSNSMYIDRPPSGKTPQQP---------PVPPQRPMAALPPPPAG--------- 203 P KP P + + P+ T +P P P+ P P PA Sbjct: 725 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 784 Query: 204 --RNHSPLPPPQTNHEE----PSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDRE---P 254 + +P P + +E ++ T+ PAP+ + T P + AP + P Sbjct: 785 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 844 Query: 255 FTLGKKPPFSDKPSIPA--------GRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP 306 T PP + + S P +S E P++ P P E + +P K P Sbjct: 845 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP 904 Query: 307 VPKHGWGPDRRENDEDDVHQRPL 329 P+ +D +R L Sbjct: 905 AATK---PEMTTTAKDKTTERDL 924 >gi|151301053 RNA binding motif protein 33 [Homo sapiens] Length = 1170 Score = 62.8 bits (151), Expect = 8e-10 Identities = 82/317 (25%), Positives = 120/317 (37%), Gaps = 66/317 (20%) Query: 136 EAPVEDDADYEPPPSNDEEALQN--------SILPAK-PFPNSNSMYIDRPPSGKTPQQ- 185 + PV A PPP ++ +++ +LP + P S + PP +TP+ Sbjct: 312 QPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMM 371 Query: 186 ---PPVPPQR-----------------------PMAALPPPPAGRNHSPLPPPQTNHEEP 219 PPV PQ+ P+ + P P G P PP H P Sbjct: 372 MTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQH-TP 430 Query: 220 SRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHL 279 N + P D+ PP P DR+PF LG S +P P+ L + Sbjct: 431 GPVPNSFSQPPRLPLQDQWRAPP-----PPQDRDPFFLG----VSGEPRFPSHLFLEQRS 481 Query: 280 PKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLP-QPALLPMS 338 P PP PP S P+P + P+P GP + + V R P +PAL P Sbjct: 482 P----PPPPPPPTLLNSSHPVP-TQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQP-- 534 Query: 339 SNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLP-PYFSQGPSNRPPIRAEGRN 397 P P+ L S PG+ + P+ LP P P++ P + Sbjct: 535 ----------PGPVGILHFS-QPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLH 583 Query: 398 FPLPLPNKPRPPSPAEE 414 PLP P++P+P P ++ Sbjct: 584 PPLPPPHQPQPQQPQQQ 600 Score = 52.0 bits (123), Expect = 1e-06 Identities = 64/259 (24%), Positives = 89/259 (34%), Gaps = 32/259 (12%) Query: 147 PPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSG--KTPQQPPVPPQRPM--AALPPPPA 202 PPP L NS + P P + + +P + QQP P +RP+ A PP P Sbjct: 482 PPPPPPPPTLLNS---SHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPV 538 Query: 203 GRNHSPLPPPQTNHEE-PSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKP 261 G H P T P R LP P +P L P + P P Sbjct: 539 GILHFSQPGSATTRPFIPPRQ-----PFLPGPG-----QPFLPTHTQPNLQGPLHPPLPP 588 Query: 262 PFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDE 321 P +P P + +H P Q P PP +H+ P + PP +H Sbjct: 589 PHQPQPQQPQQQPPPQHQPPHQPPHQPP--PQHQPPPQHPPQHPPQHQH----------H 636 Query: 322 DDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYF 381 H +P P L+PMS F P P +++ Q+ S P Sbjct: 637 HHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQ 696 Query: 382 SQGPSNRPPIRAEGRNFPL 400 P+ P + R P+ Sbjct: 697 QMQPT--APRNSNLRELPI 713 Score = 47.8 bits (112), Expect = 3e-05 Identities = 70/246 (28%), Positives = 91/246 (36%), Gaps = 52/246 (21%) Query: 183 PQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSID--RSTK 240 P QPPV PQ P PPPP PPPQ ++P RS P + Sbjct: 310 PTQPPVVPQAP----PPPP--------PPPQ---QQPIRSLFQPQPLQPLLPVQHPHHPS 354 Query: 241 PPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEH-----LPKIQKPPLPPTTERHE 295 PP + P P + PP + P P + H + +Q P LP ++ Sbjct: 355 PPQGMHMPPQLETPRMMMTPPPVT--PQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRP 412 Query: 296 RSSP--LPGKKPPVPKHGWGP-------DRRENDEDDVHQRPLPQ---PALLPMSSN-TF 342 P PG P P+H GP R +D P PQ P L +S F Sbjct: 413 AVGPQRFPG-PPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRF 471 Query: 343 PS------RSTKPSPMNP--LPSSH-----MPGAFSESNSSFPQSASLPPYFSQGPSNRP 389 PS RS P P P L SSH P F++ +F Q P + + P RP Sbjct: 472 PSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPV-RP 530 Query: 390 PIRAEG 395 ++ G Sbjct: 531 ALQPPG 536 Score = 40.4 bits (93), Expect = 0.004 Identities = 50/227 (22%), Positives = 78/227 (34%), Gaps = 45/227 (19%) Query: 149 PSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALP--PPPAGRNH 206 P++ + LQ + P P P+ P + PQQ P P +P P PPP H Sbjct: 571 PTHTQPNLQGPLHPPLPPPHQ--------PQPQQPQQQPPPQHQPPHQPPHQPPP---QH 619 Query: 207 SPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDK 266 P PP P +H L P PPL P R + S + Sbjct: 620 QP-PPQHPPQHPPQHQHHHHHHHLSVP------PPPLMPMSQPQFRPHVQTAQPQASSSR 672 Query: 267 PSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQ 326 P + L + TT ++ P+ +P P++ ++ + Sbjct: 673 MQCPQRQGLRHN-----------TTSQNVSKRPMQQMQPTAPRN-----------SNLRE 710 Query: 327 RPLPQPALLPMSS---NTFPSRSTKPSPMNPLPSSHMPGAFSESNSS 370 P+ ++ MSS + PS KP PS + G+ S + Sbjct: 711 LPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKT 757 >gi|18079216 CASK interacting protein 1 [Homo sapiens] Length = 1431 Score = 62.4 bits (150), Expect = 1e-09 Identities = 70/257 (27%), Positives = 94/257 (36%), Gaps = 46/257 (17%) Query: 140 EDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKT--PQQPPVPPQRPMAAL 197 E D P + + EA P + N RP S + P+ PP PP A Sbjct: 1144 ESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPP----AE 1199 Query: 198 PPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTL 257 PPP + PLPPP+ +P AK P S KP L + + P Sbjct: 1200 PPPTDLAHLPPLPPPEGEARKP--------AKPPV-----SPKPVLTQPVPKLQGSPTPT 1246 Query: 258 GKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKK-PPVPKHGWGPDR 316 KK P S R+ G P KPP PPT +P P K +P GP Sbjct: 1247 SKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPT-------APKPVKAVAGLPSGSAGPS- 1298 Query: 317 RENDEDDVHQRPLPQPALLPMSS-----NTFPSRSTKPS--PMNPLPSSHMPGAFSESNS 369 P P PA P ++ T PS P+ P P+ H+P + + Sbjct: 1299 -----------PAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAA 1347 Query: 370 SFPQSASLPPYFSQGPS 386 + +A+ PP +G S Sbjct: 1348 AAAAAAAAPPAPPEGAS 1364 Score = 30.0 bits (66), Expect = 5.5 Identities = 41/179 (22%), Positives = 61/179 (34%), Gaps = 39/179 (21%) Query: 148 PPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKT------PQQPPVPPQRPMAALPPPP 201 PP+ E + LP P + + +P G+ P PPVP P LPP Sbjct: 812 PPT--ERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEA 869 Query: 202 AGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPF-TLGKK 260 P + R H + A ++P D L P P+ T+ ++ Sbjct: 870 DAEPGRP------------KKRAHSLNRYAA----SDSEPERDELLVPAAAGPYATVQRR 913 Query: 261 PPFSDKPSIPAG------RSLGEHLPKIQKPPLPPTTERHERS--------SPLPGKKP 305 S PAG RS + +K P PP +R + P+P +P Sbjct: 914 VGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPPPPPKRSSSALASANLADEPVPDAEP 972 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 62.4 bits (150), Expect = 1e-09 Identities = 79/274 (28%), Positives = 90/274 (32%), Gaps = 37/274 (13%) Query: 147 PPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPP--AGR 204 PPP + LP+ P PP T PP PP P A +PPPP G Sbjct: 877 PPPPPPLPGMTVPTLPSTAIPQP-------PPLQGTEMLPPPPPPLPGAGIPPPPPLPGA 929 Query: 205 NHSPLPP-PQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPF 263 PLPP P P P P PPL + P G PP Sbjct: 930 GILPLPPLPGAGIPPPP----------PLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPP- 978 Query: 264 SDKPSIP-AGRSLGEHLPKIQKPPLPPTTERH-ERSSPLPG----KKPPVPKHGWGPDRR 317 P +P AG LP PP PP PLPG PP+P G P Sbjct: 979 ---PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1035 Query: 318 ENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASL 377 PLP + P P P P PLP + +P + P Sbjct: 1036 LPGAGIPPPPPLPGAGIPP--PPPLPGAGIPPPP--PLPGAGIPPPPPLPGAGIPPP--- 1088 Query: 378 PPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSP 411 PP G PP+ G P PLP PP P Sbjct: 1089 PPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPP 1122 Score = 55.5 bits (132), Expect = 1e-07 Identities = 78/272 (28%), Positives = 89/272 (32%), Gaps = 42/272 (15%) Query: 147 PPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNH 206 PPP A I P P P + I PP PP PP PPPP Sbjct: 987 PPPPPLPGA---GIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1040 Query: 207 SPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDK 266 P PPP P P P PPL + P G PP Sbjct: 1041 IPPPPPLPGAGIPPPP--------PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP---- 1088 Query: 267 PSIP-AGRSLGEHLPKIQKPPLPPTTERH-ERSSPLPGK----KPPVPKHGWGPDRREND 320 P +P AG LP + PP PP PLPG PP+P G P Sbjct: 1089 PPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---- 1144 Query: 321 EDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPY 380 PLP+ + P P P P PLP + +P P LP Sbjct: 1145 -------PLPRVGIPPPPP--LPGAGIPPPP--PLPGAGIPPPPPLPGVGIPPPPPLPGV 1193 Query: 381 FSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPA 412 P PP+ G P PLP PP+PA Sbjct: 1194 GIPPP---PPLPGAGIPPPPPLPGMGIPPAPA 1222 Score = 53.9 bits (128), Expect = 4e-07 Identities = 66/246 (26%), Positives = 87/246 (35%), Gaps = 36/246 (14%) Query: 167 PNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRN-HSPLPPPQTNHEEPSRSRNH 225 P S+ +D ++ QPP PP +A P + HS QT+HE S Sbjct: 791 PRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFK 850 Query: 226 KTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKP 285 + +P+P PPL + + LG PP P P LP P Sbjct: 851 NSCNIPSP-------PPLPCTESSSSMP--GLGMVPP----PPPPLPGMTVPTLPSTAIP 897 Query: 286 PLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSR 345 PP + + LP PP+P G P PLP +LP+ P Sbjct: 898 QPPPL----QGTEMLPPPPPPLPGAGIPP-----------PPPLPGAGILPLP--PLPGA 940 Query: 346 STKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNK 405 P P PLP + +P + P PP G PP+ G P PLP Sbjct: 941 GIPPPP--PLPGAAIPPPPPLPGAGIPLP---PPLPGAGIPPPPPLPGAGIPPPPPLPGA 995 Query: 406 PRPPSP 411 PP P Sbjct: 996 GIPPPP 1001 Score = 46.2 bits (108), Expect = 7e-05 Identities = 69/243 (28%), Positives = 76/243 (31%), Gaps = 41/243 (16%) Query: 147 PPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNH 206 PPP A I P P P + I PP PP PP + PPPP Sbjct: 1064 PPPPPLPGA---GIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAG 1117 Query: 207 SPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDK 266 P PPP P P P PPL R P G PP Sbjct: 1118 IPPPPPLPGAGIPPPP--------PLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPP---- 1165 Query: 267 PSIP-AGRSLGEHLPKIQKPPLPPTT-ERHERSSPLPGK--KPPVPKHGWGPDRRENDED 322 P +P AG LP + PP PP PLPG PP P G G Sbjct: 1166 PPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIP------- 1218 Query: 323 DVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSAS-LPPYF 381 P P P L P P P P+ P+ + S PQ LPP Sbjct: 1219 -----PAPAPPLPP------PGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPL 1267 Query: 382 SQG 384 G Sbjct: 1268 PSG 1270 Score = 30.4 bits (67), Expect = 4.2 Identities = 42/164 (25%), Positives = 55/164 (33%), Gaps = 28/164 (17%) Query: 91 FPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPS 150 FPE E + D E ++D +D SP EE V +DA Sbjct: 325 FPEAGPGEEAAGAPVRGAGDTDEEG---EEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEE 381 Query: 151 NDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQR---PMAALPPPPAGRNHS 207 +EEA A P S P P QR P + P Sbjct: 382 PEEEAQGPDAPAAASLPGS-----------------PAPSQRCFKPYPLITPCYIKTTTR 424 Query: 208 PLPPPQTNHEEPSRSRNH--KTAKLPAPSIDRSTKPPLDRSLAP 249 L P NH PS+S N + + P PS+ R ++ L AP Sbjct: 425 QLSSP--NH-SPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAP 465 Score = 29.6 bits (65), Expect = 7.2 Identities = 34/134 (25%), Positives = 45/134 (33%), Gaps = 26/134 (19%) Query: 181 KTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTK 240 + PQQPP P P++ P PA + + P T P + A P Sbjct: 288 REPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPV-------- 339 Query: 241 PPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGR----SLGEHLPKIQKPPLPPTTERHER 296 R D E G++ F D P G +GE P Q+ P E Sbjct: 340 ----RGAGDTDEE----GEEDAFEDAPRGSPGEEWAPEVGEDAP--QRLGEEPEEEAQGP 389 Query: 297 SSP----LPGKKPP 306 +P LPG P Sbjct: 390 DAPAAASLPGSPAP 403 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 60.5 bits (145), Expect = 4e-09 Identities = 73/279 (26%), Positives = 95/279 (34%), Gaps = 56/279 (20%) Query: 148 PPSNDEEALQNSILPAKP--FPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRN 205 PPS +L + L A P+ + PP PQ PP P+ A P PPA Sbjct: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPP----PQAPPALALPPLQAPPSPPASPP 416 Query: 206 HSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSD 265 SPL P + P PS PP+ +P P + PP Sbjct: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPS------PPVQAPFSPPASPPVSPSATPPSQA 470 Query: 266 KPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVH 325 PS+ A P +Q PP PP + S+ P + PP Sbjct: 471 PPSLAA--------PPLQVPPSPPASPPMSPSATPPPQAPP------------------- 503 Query: 326 QRPLPQP--ALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLP--PYF 381 PL P L P+ +T P P P + PG + F SASLP P Sbjct: 504 --PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG-----QAPFSPSASLPMSPLA 556 Query: 382 SQGPSNRPPIRAEGRNFPLPLPNKP------RPPSPAEE 414 + P P + A P P P RPP+P + Sbjct: 557 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 595 Score = 48.5 bits (114), Expect = 1e-05 Identities = 70/307 (22%), Positives = 104/307 (33%), Gaps = 58/307 (18%) Query: 147 PPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALP-------- 198 PP L P+ PN+ ++++ + P P P P P A+ P Sbjct: 408 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 467 Query: 199 ----------------PPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPP 242 PPA SP P P + + AK P + PP Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 527 Query: 243 LDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGE--------HLPKIQKPPLPPTTERH 294 L +P P + + PFS S+P P +Q PP PP + Sbjct: 528 LQALPSP----PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 583 Query: 295 ERSSPLPGKKPPVPKHGWGPDRRENDED---DVHQRPLPQPALLPMSSNTFP-------S 344 + ++PP P GPD + + P P P+ P S+ + P S Sbjct: 584 QAP-----RRPPTP----GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 634 Query: 345 RSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGR-NFPLPLP 403 ++ P + S GA + +A P +S+GP+ PP+ G PLP P Sbjct: 635 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA--PPLAFRGAPGAPLPWP 692 Query: 404 NKPRPPS 410 P S Sbjct: 693 PATGPGS 699 Score = 38.9 bits (89), Expect = 0.012 Identities = 45/185 (24%), Positives = 65/185 (35%), Gaps = 34/185 (18%) Query: 148 PPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVP--------PQRPMAALPP 199 PP L +L P P ++ P+ + P++PP P P+ +A P Sbjct: 558 PPPQAPPVLAAPLLQVPPSPPAS-------PTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610 Query: 200 PPAGRNHSPLP----PPQTNHEEPSRSRNHKTAKLPA-PSIDRSTKPPLDRSLAPFDREP 254 PP + SP P H + S + + P + PP D LA Sbjct: 611 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 670 Query: 255 FTLGKKPP--FSDKPSIP------AGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP 306 ++ G PP F P P G + L I + TE E ++P PG P Sbjct: 671 WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE------TEGPESATPAPGALDP 724 Query: 307 VPKHG 311 P G Sbjct: 725 GPSPG 729 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 60.5 bits (145), Expect = 4e-09 Identities = 73/279 (26%), Positives = 95/279 (34%), Gaps = 56/279 (20%) Query: 148 PPSNDEEALQNSILPAKP--FPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRN 205 PPS +L + L A P+ + PP PQ PP P+ A P PPA Sbjct: 322 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPP----PQAPPALALPPLQAPPSPPASPP 377 Query: 206 HSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSD 265 SPL P + P PS PP+ +P P + PP Sbjct: 378 LSPLATPSPQAPNALAVHLLQAPFSPPPS------PPVQAPFSPPASPPVSPSATPPSQA 431 Query: 266 KPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVH 325 PS+ A P +Q PP PP + S+ P + PP Sbjct: 432 PPSLAA--------PPLQVPPSPPASPPMSPSATPPPQAPP------------------- 464 Query: 326 QRPLPQP--ALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLP--PYF 381 PL P L P+ +T P P P + PG + F SASLP P Sbjct: 465 --PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG-----QAPFSPSASLPMSPLA 517 Query: 382 SQGPSNRPPIRAEGRNFPLPLPNKP------RPPSPAEE 414 + P P + A P P P RPP+P + Sbjct: 518 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 556 Score = 48.5 bits (114), Expect = 1e-05 Identities = 70/307 (22%), Positives = 104/307 (33%), Gaps = 58/307 (18%) Query: 147 PPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALP-------- 198 PP L P+ PN+ ++++ + P P P P P A+ P Sbjct: 369 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 428 Query: 199 ----------------PPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPP 242 PPA SP P P + + AK P + PP Sbjct: 429 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 488 Query: 243 LDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGE--------HLPKIQKPPLPPTTERH 294 L +P P + + PFS S+P P +Q PP PP + Sbjct: 489 LQALPSP----PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 544 Query: 295 ERSSPLPGKKPPVPKHGWGPDRRENDED---DVHQRPLPQPALLPMSSNTFP-------S 344 + ++PP P GPD + + P P P+ P S+ + P S Sbjct: 545 QAP-----RRPPTP----GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 595 Query: 345 RSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGR-NFPLPLP 403 ++ P + S GA + +A P +S+GP+ PP+ G PLP P Sbjct: 596 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA--PPLAFRGAPGAPLPWP 653 Query: 404 NKPRPPS 410 P S Sbjct: 654 PATGPGS 660 Score = 38.9 bits (89), Expect = 0.012 Identities = 45/185 (24%), Positives = 65/185 (35%), Gaps = 34/185 (18%) Query: 148 PPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVP--------PQRPMAALPP 199 PP L +L P P ++ P+ + P++PP P P+ +A P Sbjct: 519 PPPQAPPVLAAPLLQVPPSPPAS-------PTLQAPRRPPTPGPDTSVSGPRLTLALAPG 571 Query: 200 PPAGRNHSPLP----PPQTNHEEPSRSRNHKTAKLPA-PSIDRSTKPPLDRSLAPFDREP 254 PP + SP P H + S + + P + PP D LA Sbjct: 572 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 631 Query: 255 FTLGKKPP--FSDKPSIP------AGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP 306 ++ G PP F P P G + L I + TE E ++P PG P Sbjct: 632 WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE------TEGPESATPAPGALDP 685 Query: 307 VPKHG 311 P G Sbjct: 686 GPSPG 690 Score = 37.4 bits (85), Expect = 0.035 Identities = 62/263 (23%), Positives = 79/263 (30%), Gaps = 47/263 (17%) Query: 167 PNSNSMYIDRPP-SGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTN-----HEEPS 220 P + RPP SG+ + PP P P A P P Q E + Sbjct: 75 PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 134 Query: 221 RSRNHKTAKLPAPSID--RSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEH 278 R + + K A S R T P T G P + S AG +G Sbjct: 135 RGKATEAPKRSALSAGARRDTSGP-------------TPGTPSPAMARRSRAAGTEVGLP 181 Query: 279 LPKIQKPPLPPT---------TERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPL 329 P P PPT H + P P + P G G R + PL Sbjct: 182 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR-PSAGGGLQRPASRSLSSSATPL 240 Query: 330 PQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRP 389 PA S+ P PS P P A PP + + Sbjct: 241 SSPARSGPSARGTPRAPAHPS--QPKPKG--------------LQALRPPQVTPPRKDAA 284 Query: 390 PIRAEGRNFPLPLPNKPRPPSPA 412 P + PL P+ PPSP+ Sbjct: 285 PALGPLSSSPLATPSPSAPPSPS 307 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 60.5 bits (145), Expect = 4e-09 Identities = 71/292 (24%), Positives = 104/292 (35%), Gaps = 76/292 (26%) Query: 162 PAKPFPNSNSM--YIDRPPSGKTPQQPPVPP------------------QRPMAALPPPP 201 P P S S+ I PP+G P PP PP P + PPPP Sbjct: 687 PTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPP 746 Query: 202 AGRNH----------SPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFD 251 + +P PPP P ++ +PAP+ ++ P + ++ P Sbjct: 747 LKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTP 806 Query: 252 REPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHG 311 P PP +P+ PA PP PPT P+P P +PK Sbjct: 807 TPPV-----PPAKKQPAFPASYI----------PPSPPTP-------PVPVPPPTLPK-- 842 Query: 312 WGPDRRENDEDDVHQRPL-PQPALLPMSSNTFPSRSTKPS----PMNPLPSS---HMPGA 363 +++ PL P P+++ ++ FP T P+ P+ P+P++ P A Sbjct: 843 -----QQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPA 897 Query: 364 FSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFP----LPLPNKPRPPSP 411 P S +P P PP FP P+P P PP P Sbjct: 898 VKAKPKWQPSSIPVP-----SPDFPPPPPESSLVFPPPPPSPVPAPPPPPPP 944 Score = 57.8 bits (138), Expect = 2e-08 Identities = 61/252 (24%), Positives = 92/252 (36%), Gaps = 28/252 (11%) Query: 176 RPPSGKTPQQPPVPPQ---RPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPA 232 +PP+ Q V PQ P +PPPP P PPP T P + A Sbjct: 685 KPPTPPVMQSQSVKPQILVPPNGVVPPPP------PPPPPPT----PGSAMAQLKPAPCA 734 Query: 233 PSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTE 292 PS+ + + PP + PP P IPA L P +P T Sbjct: 735 PSLPQFSAPPPPLKIHQVQHITQVAPPTPP--PPPPIPA--PLPPQAPPKPLVTIPAPTS 790 Query: 293 RHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPM 352 + + PP P P +++ + P P +P+ T P + + + Sbjct: 791 TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKP 850 Query: 353 NPLPSSHMPGAFSESNSSFPQSASLPPYFSQ---------GPSNRPPIRAEGRNFP--LP 401 P P S +P + S FP + P SQ P + P ++A+ + P +P Sbjct: 851 PPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIP 910 Query: 402 LPNKPRPPSPAE 413 +P+ PP P E Sbjct: 911 VPSPDFPPPPPE 922 Score = 57.8 bits (138), Expect = 2e-08 Identities = 69/276 (25%), Positives = 105/276 (38%), Gaps = 57/276 (20%) Query: 147 PPPSNDEEALQNSILPAKPFPNSNSM--YIDRPPSGKTPQQPPVPPQRPMAALPPPPAGR 204 PPP +++ KP P + S+ + PP K Q + P PPPP Sbjct: 712 PPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPI-- 769 Query: 205 NHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFS 264 +PLPP + P + +PAP+ ++ P + ++ P P PP Sbjct: 770 -PAPLPP-----QAPPK----PLVTIPAPTSTKTVAPVVTQAAPPTPTPPV-----PPAK 814 Query: 265 DKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDV 324 +P+ PA PP PPT P+P P +PK +++ Sbjct: 815 KQPAFPAS----------YIPPSPPT-------PPVPVPPPTLPK-------QQSFCAKP 850 Query: 325 HQRPL-PQPALLPMSSNTFPSRSTKPS----PMNPLPSS---HMPGAFSESNSSFPQSAS 376 PL P P+++ ++ FP T P+ P+ P+P++ P A P S Sbjct: 851 PPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIP 910 Query: 377 LPPYFSQGPSNRPPIRAEGRNFPLPLPNK-PRPPSP 411 +P P PP FP P P+ P PP P Sbjct: 911 VP-----SPDFPPPPPESSLVFPPPPPSPVPAPPPP 941 Score = 50.8 bits (120), Expect = 3e-06 Identities = 76/300 (25%), Positives = 106/300 (35%), Gaps = 85/300 (28%) Query: 130 SPNEEEEAPVEDDADYEPPPSNDE--EALQNSILPAKPFPNSNSMYIDRP---PSG---K 181 SP + V+ A PPP E+ +PA P S +P PS Sbjct: 853 SPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVP 912 Query: 182 TPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKP 241 +P PP PP+ + PPPP+ P PPP T +P+ D+S P Sbjct: 913 SPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPT----------------ASPTPDKSGSP 956 Query: 242 PLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLP 301 GKK + K S P G+ KP PPT +R+ Sbjct: 957 ----------------GKK---TSKTSSPGGK----------KP--PPTPQRNSSIKSSS 985 Query: 302 GKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMP 361 G + P PK R + + V + P + + PS+ T P P P P Sbjct: 986 GAEHPEPK-------RPSVDSLVSK-------FTPPAESGSPSKETLPPPAAP----PKP 1027 Query: 362 GAFSESNSSFPQSASLPPYFSQG--PSNRPPIRAEGRN----FPLPLPNKPRPPSPAEEE 415 G + S +LP QG + P + G++ FP P + PP P E E Sbjct: 1028 GKLNLS------GVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETE 1081 Score = 49.7 bits (117), Expect = 7e-06 Identities = 72/304 (23%), Positives = 104/304 (34%), Gaps = 55/304 (18%) Query: 125 DGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQ 184 +G P P A + P+ +L P P +I + P Sbjct: 706 NGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPP 765 Query: 185 QPPVP-------PQRPMAALPPPPAGRNHSPL-----PPPQTNHEEPSRSRNHKTAKLPA 232 PP+P P +P+ +P P + + +P+ PP T P++ K PA Sbjct: 766 PPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAK----KQPAFPA 821 Query: 233 PSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPS----IPAGRSLGEHLPKIQKPPLP 288 I S P P P TL K+ F KP P + + + PP P Sbjct: 822 SYIPPSPPTP------PVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTP 875 Query: 289 PTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFP----- 343 P E S PL PVP + V +P QP+ +P+ S FP Sbjct: 876 PAME----SQPL----KPVP-----ANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPE 922 Query: 344 -SRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNR-PPIRAEGRNFPLP 401 S P P +P+P+ P P +AS P S P + + G P P Sbjct: 923 SSLVFPPPPPSPVPAPPPPP---------PPTASPTPDKSGSPGKKTSKTSSPGGKKPPP 973 Query: 402 LPNK 405 P + Sbjct: 974 TPQR 977 Score = 40.8 bits (94), Expect = 0.003 Identities = 57/259 (22%), Positives = 79/259 (30%), Gaps = 41/259 (15%) Query: 176 RPPSGKTPQQPPVPPQRPMAALPPP-PAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPS 234 R S P VPP P + P A + PLPPP P P Sbjct: 594 RMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPP------------------PPPP 635 Query: 235 IDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERH 294 PP P P P F +I ++ +H + KPP PP + Sbjct: 636 PPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQ 695 Query: 295 ERS------------SPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPAL-LPMSSNT 341 P P PP P + + Q P P L + + Sbjct: 696 SVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHI 755 Query: 342 FPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSAS---LPPYFSQG--PSNRPPIRAEGR 396 P P P+P+ P A + + P S + P +Q P+ PP+ + Sbjct: 756 TQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKK 815 Query: 397 NFPLPL----PNKPRPPSP 411 P P+ P PP P Sbjct: 816 QPAFPASYIPPSPPTPPVP 834 Score = 34.3 bits (77), Expect = 0.29 Identities = 50/230 (21%), Positives = 71/230 (30%), Gaps = 64/230 (27%) Query: 202 AGRNHSPLPPPQTNHEEPSRSRNHKT------------------AKLPAPSIDRSTKPPL 243 +G + S +P Q+NH S S T A ++ S+K + Sbjct: 536 SGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARM 595 Query: 244 DRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGK 303 + P+ PP S +P I + + P + PP PP P P Sbjct: 596 ESMNRPYT------SLVPPLSPQPKIVTPYTASQPSPPLPPPPPPP---------PPPPP 640 Query: 304 KPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPL--PSSHMP 361 PP P P P P+ S+ + K S + L S H Sbjct: 641 PPPPP-------------------PPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSG 681 Query: 362 GAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSP 411 F QS S+ P P+ P P P P PP+P Sbjct: 682 ALFKPPTPPVMQSQSVKPQILVPPNGVVP----------PPPPPPPPPTP 721 >gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sapiens] Length = 2715 Score = 60.5 bits (145), Expect = 4e-09 Identities = 79/308 (25%), Positives = 111/308 (36%), Gaps = 44/308 (14%) Query: 109 EEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPN 168 EE+ E D++GE+ + E A +++A PPP P P P Sbjct: 365 EEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPS-----PPPPLPP 419 Query: 169 SNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTA 228 ++ PP P PPV P P+ + PPPPA PPP SR R + Sbjct: 420 PST---SPPPPLCPPPPPPVSPP-PLPSPPPPPAQEEQEESPPPVV-PATCSRKRG-RPP 473 Query: 229 KLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLP 288 P+ +R +P P T PP D P++ + L I++ +P Sbjct: 474 LTPSQRAEREAARAGPEGTSPPTPTPSTATGGPP-EDSPTVAPKST--TFLKNIRQFIMP 530 Query: 289 PTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTK 348 + R R P RR DED P+P + +S P +T Sbjct: 531 VVSARSSRVIKTP--------------RRFMDEDP------PKPPKVEVSPVLRPPITTS 570 Query: 349 PS-PMNPLPSSHMPGAFSESNSSFPQSASLP-PYFSQGPSNRPPIR--AEGRNFPLPLPN 404 P P P P P A P S +P P + P R + R P P P Sbjct: 571 PPVPQEPAPVPSPPRA------PTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPA 624 Query: 405 KPRPPSPA 412 P PP+P+ Sbjct: 625 PPPPPAPS 632 Score = 58.5 bits (140), Expect = 1e-08 Identities = 74/295 (25%), Positives = 106/295 (35%), Gaps = 63/295 (21%) Query: 132 NEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQ 191 +EEEE E++ D E +E A+ ++PA + K + P PP Sbjct: 363 DEEEEKKEEEEKDKEGE-EKEERAVAEEMMPA---------------AEKEEAKLPPPPL 406 Query: 192 RPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFD 251 P A PPPP LPPP T+ P P P + + PPL P Sbjct: 407 TPPAPSPPPP-------LPPPSTSPPPP-------LCPPPPPPV---SPPPLPSPPPPPA 449 Query: 252 REPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPT--TERHERSSPLPGKKPPVPK 309 +E + PP P +PA S K +PPL P+ ER + G PP P Sbjct: 450 QEEQE--ESPP----PVVPATCSR-----KRGRPPLTPSQRAEREAARAGPEGTSPPTPT 498 Query: 310 HGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHM---PGAFSE 366 D P + P S+ + P+ SS + P F + Sbjct: 499 PSTATGGPPEDS----------PTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMD 548 Query: 367 SNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNEE 421 + P + P + PP+ E P P+P+ PR P+P L E+ Sbjct: 549 EDPPKPPKVEVSPVLRPPITTSPPVPQE----PAPVPSPPRAPTPPSTPVPLPEK 599 Score = 47.8 bits (112), Expect = 3e-05 Identities = 55/219 (25%), Positives = 78/219 (35%), Gaps = 41/219 (18%) Query: 149 PSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSP 208 P++ E A +N + P P+S PP G + PP+ + P A HSP Sbjct: 1792 PAHLEAAEENQTIVHSPAPSSE------PPGG---EDPPLDTD-----VLVPGAPERHSP 1837 Query: 209 L----PP--PQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPP 262 + PP P + P R+ A++ P+ S +P S P Sbjct: 1838 IQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPL------------ 1885 Query: 263 FSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDED 322 PS + SL H+P + P P R R SPL + P P P + + + Sbjct: 1886 ----PSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPP--PSRWASPPLKTSPQL 1939 Query: 323 DVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMP 361 V AL P S P P+P P P P Sbjct: 1940 RVPPPTSVVTALTPTSGELAP---PGPAPSPPPPEDLGP 1975 Score = 44.3 bits (103), Expect = 3e-04 Identities = 63/248 (25%), Positives = 86/248 (34%), Gaps = 50/248 (20%) Query: 131 PNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPP------SGKTPQ 184 P +E APV PPS P P + P + + P Sbjct: 572 PVPQEPAPVPSPPRAPTPPSTPV-----------PLPEKRRSILREPTFRWTSLTRELPP 620 Query: 185 QPPVPPQRPMAALPPPPAGRNHSP--LPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPP 242 PP PP P + PP PA + P L PQ E + + +++ P PP Sbjct: 621 PPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSE-AHLKIYESVLTP---------PP 670 Query: 243 LDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLG--EHLPKIQKPPLPPTTERHERS--- 297 L AP EP + PP D P+ P R++G HL + P+ T + E S Sbjct: 671 LGAPEAP---EP----EPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHG 723 Query: 298 SPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPS 357 +P P P + + P PQP L P S P M PL Sbjct: 724 APALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPS---------PQQMPPLEK 774 Query: 358 SHMPGAFS 365 + + G S Sbjct: 775 ARIAGVGS 782 Score = 36.6 bits (83), Expect = 0.059 Identities = 65/288 (22%), Positives = 89/288 (30%), Gaps = 62/288 (21%) Query: 180 GKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRST 239 G P++ +PP P+A P G SP P +T P + PAP + Sbjct: 2128 GAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPA 2187 Query: 240 -----------------------------KPPLDRSLAPFDREPFTLGKKPPFSDKPSIP 270 +PPL +++P +TL P P + Sbjct: 2188 TSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVG 2247 Query: 271 AGRSLGEHLPKIQKPPL-----------PPTTERHERSSPLPGKKPPVPKHGWGPDRREN 319 R P PPL P R +R S G+ PP P P Sbjct: 2248 VVRP----APPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAP---RL 2300 Query: 320 DEDDVHQRPLPQ-PAL-------LPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSF 371 DED PQ P L + M + T P P PG E + Sbjct: 2301 DEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEP-AGEESPGPLQERSPLL 2359 Query: 372 PQSASLPPYFSQGPSNRPPIRAEGRNFPL---PLPNKPRPPSPAEEEN 416 P PP GP P + E + ++ PPSP ++EN Sbjct: 2360 PLPEDGPPQVPDGP---PDLLLESQWHHYSGEASSSEEEPPSPDDKEN 2404 Score = 30.0 bits (66), Expect = 5.5 Identities = 47/192 (24%), Positives = 68/192 (35%), Gaps = 32/192 (16%) Query: 133 EEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQ--PPVPP 190 EEE + E D + +DE+ +S+ A R P G+ + P+PP Sbjct: 110 EEESSDGESDEEEFQGFHSDEDVAPSSLRSALRSQRG------RAPRGRGRKHKTTPLPP 163 Query: 191 QRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPF 250 R P PP P + EE + +L + R+ P RS A Sbjct: 164 PRLADVAPTPPK-------TPARKRGEEGTERMVQALTEL----LRRAQAPQAPRSRACE 212 Query: 251 DREPFTLGKKPPFSDKPSIPAGRS-----LGEHLPKIQKPPLPP--TTERHERSS----P 299 P +PP +P+ P R + E I KP PP +H+ S Sbjct: 213 PSTPRRSRGRPP--GRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKE 270 Query: 300 LPGKKPPVPKHG 311 PG P P+ G Sbjct: 271 GPGPGPGTPRRG 282 Score = 29.6 bits (65), Expect = 7.2 Identities = 37/133 (27%), Positives = 53/133 (39%), Gaps = 33/133 (24%) Query: 221 RSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLP 280 R R HKT LP PP +AP P T +K ++ + ++L E L Sbjct: 152 RGRKHKTTPLP---------PPRLADVAP--TPPKTPARKR--GEEGTERMVQALTELLR 198 Query: 281 KIQKPPLP------PTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQ------RP 328 + Q P P P+T R R P PG+ GP RR+ V + +P Sbjct: 199 RAQAPQAPRSRACEPSTPRRSRGRP-PGRPA-------GPCRRKQQAVVVAEAAVTIPKP 250 Query: 329 LPQPALLPMSSNT 341 P P ++P+ T Sbjct: 251 EPPPPVVPVKHQT 263 >gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo sapiens] Length = 309 Score = 60.1 bits (144), Expect = 5e-09 Identities = 65/244 (26%), Positives = 88/244 (36%), Gaps = 36/244 (14%) Query: 176 RPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEE--PSRSRNHKTAKLPAP 233 RP G PQ+ P PP +P PP G N S PPP+ E P + N P P Sbjct: 40 RPQGGNQPQRTPPPPGKPEGR---PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRP 96 Query: 234 SIDRSTKPPL-DRSLAPFDREPFTLGKKPPFSDKPSIP---AGRSLGEHLPKIQKPPLPP 289 P ++S P PP KP P G P+ KP PP Sbjct: 97 GKPEGQPPQGGNQSQGP-----------PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPP 145 Query: 290 TTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKP 349 ++ P PP P GP + ++ Q P P P ++S P Sbjct: 146 PQGGNQSQGP-----PPRPGKPEGPPPQGGNQS---QGPPPHPGKPEGPPPQGGNQSQGP 197 Query: 350 SPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPP 409 P P P ++S P+ P +GP ++ + +G P P P KP+ P Sbjct: 198 PPRPGKPEGPPPQGGNQSQGPPPR-----PGKPEGPPSQGGNKPQG---PPPHPGKPQGP 249 Query: 410 SPAE 413 P E Sbjct: 250 PPQE 253 Score = 57.4 bits (137), Expect = 3e-08 Identities = 84/318 (26%), Positives = 102/318 (32%), Gaps = 62/318 (19%) Query: 114 ESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMY 173 +S N+D E+ S E P + PP P KP Sbjct: 17 QSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPP-----------PGKPE------- 58 Query: 174 IDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAP 233 RPP G Q PP RP PPP G N S PPP+ E + ++ P P Sbjct: 59 -GRPPQGGNQSQG--PPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPP 115 Query: 234 SIDRSTKPPL---DRSLAPFDREPFTLGKKPPFSDKPSIP---AGRSLGEHLPKIQKPPL 287 + PP ++S P PP KP P G P+ KP Sbjct: 116 RPGKPEGPPPQGGNQSQGP-----------PPRPGKPEGPPPQGGNQSQGPPPRPGKPEG 164 Query: 288 PPTT--ERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSR 345 PP + + P PGK P G + + P PQ S P R Sbjct: 165 PPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGG---NQSQGPPPR 221 Query: 346 STKP---------SPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGR 396 KP P P P P + PQ PP QGP PP G Sbjct: 222 PGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPP-PPGRPQGP---PP---PGG 274 Query: 397 NFPLPLP---NKPRPPSP 411 N PLP KP+ P P Sbjct: 275 NPQQPLPPPAGKPQGPPP 292 Score = 55.1 bits (131), Expect = 2e-07 Identities = 55/204 (26%), Positives = 70/204 (34%), Gaps = 28/204 (13%) Query: 114 ESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMY 173 E P + G P + E P + + PP + P P P + Sbjct: 121 EGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGK-------PEGPPPQGGNQS 173 Query: 174 IDRPPSGKTPQQPPV--------PPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNH 225 PP P+ PP PP RP PPP G N S PPP+ E S+ Sbjct: 174 QGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGG 233 Query: 226 KTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLP----K 281 + P P + PP P R P PP + P G + + LP K Sbjct: 234 NKPQGPPPHPGKPQGPPPQEGNKP-QRPP------PPGRPQGPPPPGGNPQQPLPPPAGK 286 Query: 282 IQKPPLPPTTERHERSSPLPGKKP 305 Q PP PP R R P G+ P Sbjct: 287 PQGPPPPPQGGRPHR--PPQGQPP 308 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 59.7 bits (143), Expect = 6e-09 Identities = 85/374 (22%), Positives = 141/374 (37%), Gaps = 91/374 (24%) Query: 78 RRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEA 137 ++ + KP VP PE ES + +EE + +P ++ +P EE+ Sbjct: 10780 KKPVLEEKPAVP-VPERAESPPPE-----VYEEPEEIAPEEEI---------APEEEKPV 10824 Query: 138 PVEDDADYE-PPPSNDEEALQNSILPAKPFPNSNSMYIDRP--PSGKTPQQPPVPPQRPM 194 PV ++ + E PPP+ EE P K P I +P P K P+ V + + Sbjct: 10825 PVAEEEEPEVPPPAVPEE-------PKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKL 10877 Query: 195 AALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPA-PSIDRSTK-PPLD-------- 244 PPPP P PP + E+ + + K+P P + + PL Sbjct: 10878 KPRPPPPP-----PAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKV 10932 Query: 245 RSLAPFDREPF--------TLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLP-------- 288 R L P +R+P ++ +K P ++P + + P + +PP P Sbjct: 10933 RKLLP-ERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEV 10991 Query: 289 PTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTK 348 PT + ER P P K P + + +P PA P ++ K Sbjct: 10992 PTVTKRERKIPEPTKVPEI------------------KPAIPLPAPEPKPKPEAEVKTIK 11033 Query: 349 PSPMNPLPSS-----HMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLP 403 P P+ P P+ +P ++ + P+ + P + PI+ + P P+ Sbjct: 11034 PPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKP--------KGPIKGVPKKTPSPIE 11085 Query: 404 ---NKPRPPSPAEE 414 K RP S E+ Sbjct: 11086 AERRKLRPGSGGEK 11099 Score = 52.4 bits (124), Expect = 1e-06 Identities = 82/376 (21%), Positives = 129/376 (34%), Gaps = 61/376 (16%) Query: 76 EERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEE- 134 +ER + + +V PEE E HE + FEE ++ + E E E Sbjct: 10362 KERLELEVVEAEVEEIPEEEEFHEVEE----YFEEGEFHEVEEFIKLEQHRVEEEHRVEK 10417 Query: 135 --------EEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSG------ 180 E VE + PP E + I+P K P + + PP+ Sbjct: 10418 VHRVIEVFEAEEVEVFEKPKAPPKGPE--ISEKIIPPKK-PPTKVVPRKEPPAKVPEVPK 10474 Query: 181 --------KTPQQPPVPPQRPMAALPP-----------PPAGRNHSPLPPPQTNHEEPSR 221 + P++P VPP + LPP PPA + P PP E P Sbjct: 10475 KIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKK---PEAPPPKVPEAPKE 10531 Query: 222 SRNHKTAKLP---APSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEH 278 K +P P + + P + ++ P + P + KP S P +P E Sbjct: 10532 VVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPE-SPPPEVPEAPK--EV 10588 Query: 279 LPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMS 338 +P+ + P PP ++ P K P PK P+++ ++P P +P Sbjct: 10589 VPEKKVPAAPP-----KKPEVTPVKVPEAPKE-VVPEKKVPVPPP--KKPEVPPTKVPEV 10640 Query: 339 SNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNF 398 P + P P S P F E + P+ P + + Sbjct: 10641 PKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKK- 10699 Query: 399 PLPLPNKPRPPSPAEE 414 P+P K P A++ Sbjct: 10700 --PVPEKKAPAVVAKK 10713 Score = 52.0 bits (123), Expect = 1e-06 Identities = 79/320 (24%), Positives = 116/320 (36%), Gaps = 58/320 (18%) Query: 129 ESPNE---EEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQ 185 E+P E E++ P E P EA ++P K P + PP+ K P+ Sbjct: 10583 EAPKEVVPEKKVPAAPPKKPEVTPVKVPEA-PKEVVPEKKVPVPPPKKPEVPPT-KVPEV 10640 Query: 186 PPV--PPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKL---PAPSID-RST 239 P V P ++ A+PP P PPP+ E + A++ P P+ + T Sbjct: 10641 PKVAVPEKKVPEAIPPKPES------PPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVT 10694 Query: 240 KPPLDRSLAPFDREPFTLGKKP--PFSDKPSIPAGRSLGEHLPKI--QKPPLPPTTERHE 295 PP + P + P + KKP P P +P + +P + +KP PP Sbjct: 10695 VPP--KKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEV 10752 Query: 296 RSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPS-PMNP 354 +P KK VPK +P PA +P P KP+ P+ Sbjct: 10753 PKEVVPEKKVAVPK-----------------KPEVPPAKVPEVPKK-PVLEEKPAVPVPE 10794 Query: 355 LPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPA-- 412 S P + E P+ P E + P+ +P P PA Sbjct: 10795 RAESPPPEVYEEPEEIAPEEEIAPE--------------EEKPVPVAEEEEPEVPPPAVP 10840 Query: 413 EEENSLNEEWYVSYITRPEA 432 EE + E V I +PEA Sbjct: 10841 EEPKKIIPEKKVPVIKKPEA 10860 Score = 50.1 bits (118), Expect = 5e-06 Identities = 75/346 (21%), Positives = 112/346 (32%), Gaps = 76/346 (21%) Query: 129 ESPNEEEEAPVEDDADYEPPPSNDEEAL-----QNSILPAKPFPNSNSMYIDRPPSGKTP 183 ESP E E+ A EPP EE Q ++ P KP P + + K P Sbjct: 10659 ESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAV----VAKKP 10714 Query: 184 QQPPVP-PQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPP 242 + PPV P+ P +P PL P+ P++ +P + KP Sbjct: 10715 ELPPVKVPEVPKEVVPEKKV-----PLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPE 10769 Query: 243 LDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKI-------------------- 282 + + P + KKP +KP++P P++ Sbjct: 10770 VPPAKVP------EVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKP 10823 Query: 283 ------QKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQ------RPLP 330 ++P +PP E +P KK PV K P +E + + V + RP P Sbjct: 10824 VPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPP 10883 Query: 331 QPALLPMSS--------NTFPSRSTKPSPMNP----LPSSHMPGAFSESNSSFP------ 372 P P P + P P L +PG + P Sbjct: 10884 PPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEP 10943 Query: 373 -QSASLPPYFSQGPSNRPPIRAEGRNF---PLPLPNKPRPPSPAEE 414 + L + P P + E + P +P PP P EE Sbjct: 10944 KEEVVLKSVLRKRPEEEEP-KVEPKKLEKVKKPAVPEPPPPKPVEE 10988 Score = 48.5 bits (114), Expect = 1e-05 Identities = 82/378 (21%), Positives = 132/378 (34%), Gaps = 63/378 (16%) Query: 84 RKPQVPR--------FPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDD---------- 125 R P+VP+ F EE +H E+ + EE++Y ++ E++ Sbjct: 9895 RVPEVPKELEPEEVAFEEEVVTHVEE---YLVEEEEEYIHEEEEFITEEEVVPVIPVKVP 9951 Query: 126 GDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYI--DRPPSGKTP 183 P EE+ PV E PP+ E +P KP + ++PP K P Sbjct: 9952 EVPRKPVPEEKKPVPVPKKKEAPPAKVPE------VPKKPEEKVPVLIPKKEKPPPAKVP 10005 Query: 184 QQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAP---SIDRSTK 240 + P P +P P PP E P + K +PAP + Sbjct: 10006 EVPKKPVPEEKVPVPVPKKVE-----APPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKV 10060 Query: 241 PPLDRSLAPFDREPFTLGKK---PPFSDKPSIPAGRS---LGEHLPK-----IQKPPLPP 289 P + + L P +++P + KK PP P +P R + LP+ ++ +P Sbjct: 10061 PEVPKKLIPEEKKPTPVPKKVEAPP----PKVPKKREPVPVPVALPQEEEVLFEEEIVPE 10116 Query: 290 TTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSR---- 345 E LP ++ +P+ E + + P P+ +P P Sbjct: 10117 EEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVP-PEEEYVPEEEEFVPEEEVLP 10175 Query: 346 STKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNK 405 KP P P + +E P+ PP P + E + LP + Sbjct: 10176 EVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPP----AKVPEVPKKVEEKRIILPKEEE 10231 Query: 406 PRPPSPAE--EENSLNEE 421 P E EE ++EE Sbjct: 10232 VLPVEVTEEPEEEPISEE 10249 Score = 47.0 bits (110), Expect = 4e-05 Identities = 92/440 (20%), Positives = 150/440 (34%), Gaps = 90/440 (20%) Query: 62 VPILSKLSQ---EINKN---EERRSIFTRKPQ--VPRFPEETESHEEDNGGWSSFEEDD- 112 VP+ K E++K EE+R + K VP+ E T WS EE++ Sbjct: 9444 VPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEG 9503 Query: 113 ------YESPNDDQDGEDDGDYESPNEEEEAPVEDDADY-----EPPPSNDEEALQNSIL 161 E ++++ + +YE E EE VE+ E P+ E + I+ Sbjct: 9504 VSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIV 9563 Query: 162 PAKPFPNSNSMYIDRPPSGKTPQQP-----------PVP----------PQRPMAALP-- 198 P I+ PP K P+ P PVP P+ P +P Sbjct: 9564 LKPKIPAK----IEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEK 9619 Query: 199 --PPPAGRNHSPLPPPQTN-HEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPF 255 PP + PLP T H + ++ A + ++ P + P ++ Sbjct: 9620 KVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEK--- 9676 Query: 256 TLGKKPPFSDKPS---------IPAGRSLGEHLPKIQKPPLPPTT--ERHERSSPLPGKK 304 L KP ++P + + PK + P+ T E ER+ L + Sbjct: 9677 VLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEA 9736 Query: 305 PPVPKHGWGPDRREND-----------EDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMN 353 V + + E D E D ++ + + + KP P+ Sbjct: 9737 VSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVK 9796 Query: 354 PLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAE 413 P+P +P + P++ P + P+ P+P KP PP E Sbjct: 9797 PVPEEPVP--------TKPKAPPAKVLKKAVPEEKVPV-------PIPKKLKPPPPKVPE 9841 Query: 414 EENSLNEEWYVSYITRPEAE 433 E + EE IT+ E E Sbjct: 9842 EPKKVFEEKIRISITKREKE 9861 Score = 46.2 bits (108), Expect = 7e-05 Identities = 89/439 (20%), Positives = 146/439 (33%), Gaps = 101/439 (23%) Query: 70 QEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYE 129 +E+ EE+ +T + + E E E + + FEE + D + ++ +YE Sbjct: 9718 KEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYE 9777 Query: 130 SPNEEEE-----------APVEDDADYEPPPSNDEEALQNSILPAK-PFPNSNSMYIDRP 177 E EE PV ++ P + + L+ ++ K P P + +P Sbjct: 9778 RYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKL---KP 9834 Query: 178 PSGKTPQQP---------------------------PVPPQRPMAALPPPPAGRNHSP-- 208 P K P++P P+ P+R +A P + +P Sbjct: 9835 PPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPV 9894 Query: 209 --------LPPPQTNHEEP-----------------SRSRNHKTAKLPAPSIDRSTKPPL 243 L P + EE T + P I P + Sbjct: 9895 RVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKV-PEV 9953 Query: 244 DRSLAPFDREPFTLGKK--PPFSDKPSIP--AGRSLGEHLPKIQKPPLPPTTERHERSSP 299 R P +++P + KK P + P +P + +PK +KPP E ++ P Sbjct: 9954 PRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVP 10013 Query: 300 LPGKKPPVPKHGWGPDRR--ENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPS 357 PVPK P + E + V ++ +P PA + + P P +P Sbjct: 10014 EEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEA---PPAKVPEVPKKLIPE 10070 Query: 358 SHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENS 417 P + P+ PP + P R P+ P+P+ P EEE Sbjct: 10071 EKKP-------TPVPKKVEAPP--PKVPKKREPV-------PVPV------ALPQEEEVL 10108 Query: 418 LNEEWYVSYITRPEAEAAL 436 EE PE E L Sbjct: 10109 FEEEIVPEEEVLPEEEEVL 10127 Score = 38.9 bits (89), Expect = 0.012 Identities = 41/173 (23%), Positives = 66/173 (38%), Gaps = 21/173 (12%) Query: 146 EPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRN 205 E P EE + S+L +P + + K P P PP +P+ + P + Sbjct: 10938 ERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKR 10997 Query: 206 HSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLD-RSLAPFDREPF--------- 255 +P EP++ K A +P P+ + KP + +++ P EP Sbjct: 10998 ERKIP-------EPTKVPEIKPA-IPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVT 11049 Query: 256 --TLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP 306 +GKK + P A + G +K P P ER + G+KPP Sbjct: 11050 VPVVGKKAE-AKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPP 11101 Score = 38.1 bits (87), Expect = 0.020 Identities = 68/372 (18%), Positives = 129/372 (34%), Gaps = 35/372 (9%) Query: 93 EETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSND 152 EE + + E G+ EE+ E+ + + + + + E + P + PPP Sbjct: 9121 EEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPP-- 9178 Query: 153 EEALQNSILPAKPFPNSNSMYIDRPPSGKTPQ-QPPVPPQRPMAALPPPPAGRNHSPLPP 211 + ++ ++ K S M ++ K P+ + PQ+P P + Sbjct: 9179 -KVIKKPVIE-KIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRT----PVQEEVIEVKV 9232 Query: 212 PQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKK----PPFSDKP 267 P + ++ S T P + + + ++ + K+ P + P Sbjct: 9233 PAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELP 9292 Query: 268 SIPAGRSLGE-HLPKIQKPPLPPTTERHERSSPLPGKKPPVP---KHGWGPDRRENDEDD 323 PA + +PK +PP P E ++ P+P +K PVP K P + + Sbjct: 9293 EKPAPEEVAPVPIPKKVEPPAPKVPEVPKK--PVPEEKKPVPVPKKEPAAPPK----VPE 9346 Query: 324 VHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYF-- 381 V ++P+P+ + P K +P +P E + Q PP Sbjct: 9347 VPKKPVPEEKI------PVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVP 9400 Query: 382 ----SQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALR 437 + P R P+ + P P P P EE P AE + + Sbjct: 9401 EIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKK 9460 Query: 438 KINQDGTFLVRD 449 + ++ F+ + Sbjct: 9461 TVVEEKRFVAEE 9472 Score = 33.1 bits (74), Expect = 0.65 Identities = 61/265 (23%), Positives = 92/265 (34%), Gaps = 49/265 (18%) Query: 56 KFPKLR--VPILSKLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDY 113 K PK R VP+ L QE E + P+ PEE E E+ E++ Sbjct: 10087 KVPKKREPVPVPVALPQEEEVLFEEEIV----PEEEVLPEEEEVLPEEE---EVLPEEEE 10139 Query: 114 ESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFP------ 167 P ++ E P EEEE P E++ E EE + + P P P Sbjct: 10140 VLPEEE---------EIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEI 10190 Query: 168 ----NSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSR 223 + I + + P VP + + P + LP T E Sbjct: 10191 KKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILP---KEEEVLPVEVTEEPEEEPIS 10247 Query: 224 NHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQ 283 + + P PSI+ +AP R P + K P + P +P K++ Sbjct: 10248 EEEIPEEP-PSIEEV------EEVAP-PRVPEVIKKAVPEAPTP-VP---------KKVE 10289 Query: 284 KPPLPPTTERHERSSPLPGKKPPVP 308 PP + + E P+P +K P Sbjct: 10290 APPAKVSKKIPEEKVPVPVQKKEAP 10314 >gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo sapiens] Length = 245 Score = 59.7 bits (143), Expect = 6e-09 Identities = 58/214 (27%), Positives = 73/214 (34%), Gaps = 43/214 (20%) Query: 149 PSNDEEALQNSILPAK-PF-PNSNSMYIDRPPSGKTPQQP-PVPPQRPMAALPPPPAGRN 205 PS+ L S P+ PF P MY PP+G P P P PP P PPP G Sbjct: 46 PSSVPSGLPPSATPSTVPFGPAPTGMYPSVPPTGPPPGPPAPFPPSGPSC---PPPGGPY 102 Query: 206 HSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSD 265 +P P P + + T +P P + R P D P G P+ Sbjct: 103 PAPTVPG------PGPTGPYPTPNMPFPELPRPYGAPTD---------PAAAGPLGPWGS 147 Query: 266 KPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVP-----KHGWGPDRREND 320 S P +G P P P PG PPVP WGP Sbjct: 148 MSSGPWAPGMGGQYPTPNMPYPSPGPYPAPPPPQAPGAAPPVPWGTVPPGAWGP------ 201 Query: 321 EDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNP 354 PA P + ++P+ P+P NP Sbjct: 202 -----------PAPYPAPTGSYPTPGLYPTPSNP 224 Score = 38.1 bits (87), Expect = 0.020 Identities = 35/117 (29%), Positives = 45/117 (38%), Gaps = 8/117 (6%) Query: 296 RSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPL 355 ++S + KP P GW N+ P P+ LP S+ T + P+P Sbjct: 18 KTSAVSNTKPGQPPQGWPGSNPWNNPS----APSSVPSGLPPSA-TPSTVPFGPAPTGMY 72 Query: 356 PSSHMPGAFSESNSSFPQSA-SLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSP 411 PS G + FP S S PP GP P + G P P PN P P P Sbjct: 73 PSVPPTGPPPGPPAPFPPSGPSCPP--PGGPYPAPTVPGPGPTGPYPTPNMPFPELP 127 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 59.3 bits (142), Expect = 8e-09 Identities = 77/338 (22%), Positives = 121/338 (35%), Gaps = 61/338 (18%) Query: 109 EEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPN 168 E+ D + + G + ES +E + ED ++ E P + ++ K + Sbjct: 684 EKVDVIAGSSKMKGFSSSESESSSESSSSDSED-SETEMAPKSKKKGHPGR--EQKKHHH 740 Query: 169 SNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTA 228 + + + P+ PQQPP PPQ+P PPPP + P PPP Sbjct: 741 HHHQQMQQAPA-PVPQQPPPPPQQPP---PPPPPQQQQQPPPPP---------------- 780 Query: 229 KLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGR-----------SLGE 277 P PS+ + P + S PF + +P P G L Sbjct: 781 --PPPSMPQQAAPAMKSSPPPFIATQVPV-LEPQLPGSVFDPIGHFTQPILHLPQPELPP 837 Query: 278 HLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPM 337 HLP+ + PP +H SP P +P+ P R N + +P PA+ P Sbjct: 838 HLPQPPEHSTPPHLNQHAVVSP-PALHNALPQQ---PSRPSNRAAALPPKPARPPAVSPA 893 Query: 338 SSNT----FPSRSTKPS--------PMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQG- 384 + T P + P P PL S M + P + LP Q Sbjct: 894 LTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQ 953 Query: 385 ------PSNRPPIRAEGRNFPLPLPNKPRPPSPAEEEN 416 P P ++ + + P P P P+P P ++++ Sbjct: 954 PPPPLPPPPHPSVQQQLQQQP-PPPPPPQPQPPPQQQH 990 Score = 57.0 bits (136), Expect = 4e-08 Identities = 86/385 (22%), Positives = 137/385 (35%), Gaps = 61/385 (15%) Query: 139 VEDDADYEPPPSNDEEALQ----NSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPM 194 +ED+ PP ++ + L + P P S + PP P P V Q Sbjct: 913 LEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQ 972 Query: 195 AALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREP 254 PPPP P PPPQ H+ P R + + P +PP + P P Sbjct: 973 QPPPPPPP----QPQPPPQQQHQPPPRPVHLQ----PMQFSTHIQQPPPPQGQQPPHPPP 1024 Query: 255 FTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGP 314 G++PP +P+ P H P+ K T E SPL P + + Sbjct: 1025 ---GQQPP-PPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQF---- 1076 Query: 315 DRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSS--HMPGAFSESNS--- 369 + HQ P PQ + P + +P P+ + H P SE S Sbjct: 1077 ------QSLTHQSP-PQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSL 1129 Query: 370 -----SFPQSASLPPYFSQGPS------NRPPIRAEGRNFPLP-LPNKPR-------PPS 410 P+S P + Q P RP IR +N P P P+K + P + Sbjct: 1130 RPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVA 1189 Query: 411 PAEEENSLNEEWYVSYITR-PEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKV 469 P ++ N + S + + P ++ K + D R ++++ ++K Sbjct: 1190 PKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEE---------REKA 1240 Query: 470 YNIQIRYQKESQVYLLGTGLRGKED 494 Q + ++ + L +R +ED Sbjct: 1241 LKAQAEHAEKEKERLRQERMRSRED 1265 Score = 34.3 bits (77), Expect = 0.29 Identities = 29/113 (25%), Positives = 42/113 (37%), Gaps = 10/113 (8%) Query: 165 PFPN-SNSMYIDRPPSGKTPQQP-----PVPPQRPMAALPPPPAGRNHSPL----PPPQT 214 PFP + + + P P QP PVPPQ P P ++H P+ P P Sbjct: 224 PFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVK 283 Query: 215 NHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKP 267 + R + T P + + PP ++ R + KPP D P Sbjct: 284 TKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVP 336 Score = 32.3 bits (72), Expect = 1.1 Identities = 49/217 (22%), Positives = 69/217 (31%), Gaps = 48/217 (22%) Query: 129 ESPNEEEEAPV----------EDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPP 178 E P EE E + ++ +P S Q S P P N + P Sbjct: 163 ELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATP 222 Query: 179 SGKTPQQPPVPPQRPMAALPPPPAGRNHSPLP----PPQTNHEEPSRSRNHKTAKLPAPS 234 P + Q P+ + PP + P+P PP +P +S A P P Sbjct: 223 HPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPV 282 Query: 235 IDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERH 294 TK + R P T+ P + PS+ PP P TT+ Sbjct: 283 ---KTKKGVKRKAD--TTTPTTI---DPIHEPPSL---------------PPEPKTTKLG 319 Query: 295 ERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQ 331 +R KPP + D D Q P P+ Sbjct: 320 QRRESSRPVKPP-----------KKDVPDSQQHPAPE 345 Score = 31.6 bits (70), Expect = 1.9 Identities = 29/138 (21%), Positives = 50/138 (36%), Gaps = 3/138 (2%) Query: 186 PPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDR 245 P VPP + A PP + + ++ ++ R + A+L ++ L Sbjct: 471 PAVPPPTKVVA-PPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQL--KAVHEQLAA 527 Query: 246 SLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKP 305 P +P K K + E+ K P P T+++ S+ KK Sbjct: 528 LSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKE 587 Query: 306 PVPKHGWGPDRRENDEDD 323 P P P E++E+D Sbjct: 588 PAPMKSKPPPTYESEEED 605 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 59.3 bits (142), Expect = 8e-09 Identities = 91/365 (24%), Positives = 132/365 (36%), Gaps = 58/365 (15%) Query: 67 KLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGE-DD 125 K S + K E + + K Q + +TE E D + + PN +GE + Sbjct: 76 KKSAKKVKEEASSPLKSNKRQREKVASDTE--EADRTSSKKTKTQEISRPNSPSEGEGES 133 Query: 126 GDYESPNEEEEAPVED-DADYE------PPPSNDEE----ALQNSILPAKPFPNSNSMYI 174 D S N+E + +D D D P P ++E + Q +L A+P P + Sbjct: 134 SDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQP-PALQA--- 189 Query: 175 DRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPS 234 P+G TP PP P P P P T + P++ + TA +P Sbjct: 190 ---PTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQ-APTAPVPHTH 245 Query: 235 IDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERH 294 I ++ P ++PP P P+ PPL P T Sbjct: 246 IQQA---------------PALHPQRPPSPHPPPHPS-----------PHPPLQPLTGSA 279 Query: 295 ERSSPLPGKKPPVPKHGWGPDRREN-DEDDVHQRP-LPQP-ALLPMSSNTFPSRSTKPSP 351 + S +PP+ HG GP + + Q P PQP L P +S T P+ Sbjct: 280 GQPSAPSHAQPPL--HGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAA 337 Query: 352 MNPLPSSHMPGAFSESNSSF-PQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRP-- 408 P S +P + S S P+ LPP P +PP P P +K P Sbjct: 338 AYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL 397 Query: 409 --PSP 411 PSP Sbjct: 398 SGPSP 402 Score = 40.4 bits (93), Expect = 0.004 Identities = 51/218 (23%), Positives = 71/218 (32%), Gaps = 39/218 (17%) Query: 136 EAPVEDDADYEPPPSNDEEALQNSILPAKP-FPNSNSMYIDRPPSGKTPQQPPVPPQRPM 194 + P + P S N+ LP P +S+ PPS P +P +P+ Sbjct: 384 QLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPL 443 Query: 195 AALPPPPAGRNHSP-LPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDRE 253 + P P G S LPPP +H H+ A P PF + Sbjct: 444 PSSPAQPPGLTQSQNLPPPPASHPPTGL---HQVAPQP-----------------PFAQH 483 Query: 254 PFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWG 313 PF G PP + P+ P+ + +PP S G P+P Sbjct: 484 PFVPGGPPPIT-PPTCPSTSTPPAGPGTSAQPPCSGAAA--SGGSIAGGSSCPLPT---- 536 Query: 314 PDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSP 351 +E DD + P P P RS P P Sbjct: 537 VQIKEEALDDAEEPESPPP----------PPRSPSPEP 564 Score = 38.1 bits (87), Expect = 0.020 Identities = 55/237 (23%), Positives = 77/237 (32%), Gaps = 48/237 (20%) Query: 173 YIDRPPSGKTPQQP-PVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLP 231 +I PP+ PQ P P + P P P N + LPPP S S +H + P Sbjct: 373 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN-ANLPPPPALKPLSSLSTHHPPSAHP 431 Query: 232 APSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTT 291 PPL + + P P+ P G + ++LP Sbjct: 432 ---------PPLQ-----------LMPQSQPLPSSPAQPPGLTQSQNLP----------- 460 Query: 292 ERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSP 351 P P PP H P + Q P P++ T PS ST P+ Sbjct: 461 -------PPPASHPPTGLHQVAP------QPPFAQHPFVPGGPPPITPPTCPSTSTPPA- 506 Query: 352 MNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRP 408 P S+ P + + ++ S P + AE P P P P P Sbjct: 507 -GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSP 562 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.133 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,193,250 Number of Sequences: 37866 Number of extensions: 2060615 Number of successful extensions: 26727 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 496 Number of HSP's successfully gapped in prelim test: 1583 Number of HSP's that attempted gapping in prelim test: 11823 Number of HSP's gapped (non-prelim): 8692 length of query: 533 length of database: 18,247,518 effective HSP length: 107 effective length of query: 426 effective length of database: 14,195,856 effective search space: 6047434656 effective search space used: 6047434656 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.