Guide to the Human Genome
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Search of human proteins with 5031855

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5031855 lymphocyte cytosolic protein 2 [Homo sapiens]
         (533 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5031855 lymphocyte cytosolic protein 2 [Homo sapiens]             1115   0.0  
gi|7019535 B-cell linker isoform 1 [Homo sapiens]                     143   4e-34
gi|166235901 B-cell linker isoform 2 [Homo sapiens]                   127   3e-29
gi|193083221 mast cell immunoreceptor signal transducer [Homo sa...   127   3e-29
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    84   3e-16
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    84   3e-16
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     77   4e-14
gi|38348280 SH2 domain containing 6 [Homo sapiens]                     73   6e-13
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         72   2e-12
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    70   4e-12
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    69   1e-11
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    68   2e-11
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]              68   2e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    67   4e-11
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   65   2e-10
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   65   2e-10
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   65   2e-10
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    65   2e-10
gi|151301053 RNA binding motif protein 33 [Homo sapiens]               63   8e-10
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  62   1e-09
gi|160707881 formin 2 [Homo sapiens]                                   62   1e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    60   4e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    60   4e-09
gi|47132519 Ras association and pleckstrin homology domains 1 is...    60   4e-09
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    60   4e-09
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    60   5e-09
gi|110349719 titin isoform N2-A [Homo sapiens]                         60   6e-09
gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho...    60   6e-09
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    59   8e-09
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          59   8e-09

>gi|5031855 lymphocyte cytosolic protein 2 [Homo sapiens]
          Length = 533

 Score = 1115 bits (2885), Expect = 0.0
 Identities = 533/533 (100%), Positives = 533/533 (100%)

Query: 1   MALRNVPFRSEVLGWDPDSLADYFKKLNYKDCEKAVKKYHIDGARFLNLTENDIQKFPKL 60
           MALRNVPFRSEVLGWDPDSLADYFKKLNYKDCEKAVKKYHIDGARFLNLTENDIQKFPKL
Sbjct: 1   MALRNVPFRSEVLGWDPDSLADYFKKLNYKDCEKAVKKYHIDGARFLNLTENDIQKFPKL 60

Query: 61  RVPILSKLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQ 120
           RVPILSKLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQ
Sbjct: 61  RVPILSKLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQ 120

Query: 121 DGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSG 180
           DGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSG
Sbjct: 121 DGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSG 180

Query: 181 KTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTK 240
           KTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTK
Sbjct: 181 KTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTK 240

Query: 241 PPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPL 300
           PPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPL
Sbjct: 241 PPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPL 300

Query: 301 PGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHM 360
           PGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHM
Sbjct: 301 PGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHM 360

Query: 361 PGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNE 420
           PGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNE
Sbjct: 361 PGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNE 420

Query: 421 EWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKES 480
           EWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKES
Sbjct: 421 EWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKES 480

Query: 481 QVYLLGTGLRGKEDFLSVSDIIDYFRKMPLLLIDGKNRGSRYQCTLTHAAGYP 533
           QVYLLGTGLRGKEDFLSVSDIIDYFRKMPLLLIDGKNRGSRYQCTLTHAAGYP
Sbjct: 481 QVYLLGTGLRGKEDFLSVSDIIDYFRKMPLLLIDGKNRGSRYQCTLTHAAGYP 533


>gi|7019535 B-cell linker isoform 1 [Homo sapiens]
          Length = 456

 Score =  143 bits (360), Expect = 4e-34
 Identities = 135/502 (26%), Positives = 192/502 (38%), Gaps = 99/502 (19%)

Query: 54  IQKFPKLRVPILSKLSQ------EINKNEE------RRSIFTRKPQVPRFPEETESHEED 101
           + K  K+ VP   KL Q      +I  NE       ++      P VPR    +ES  ++
Sbjct: 1   MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE 60

Query: 102 NGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSIL 161
              WS   + DYE+P++  D E    Y  P EE       D  YEPPP   E      + 
Sbjct: 61  EEQWSDDFDSDYENPDEHSDSEM---YVMPAEENA-----DDSYEPPPVEQET---RPVH 109

Query: 162 PAKPFPNSNSMYIDR-------PPSGKT-PQQPPVPPQRPMAALPPPPAGRNHSPLPPPQ 213
           PA PF      YID        PP  KT P +P  P ++       P       P  PP+
Sbjct: 110 PALPFARGE--YIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPK 167

Query: 214 TNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGR 273
                     +     +P    D +   P + S  P ++ P       P S  P+ P G 
Sbjct: 168 PK----GLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGT 223

Query: 274 SLGEHLPKIQKPPLPPTTERHERSSPLP--GKKPPVPKHGWGPDRRENDEDDVHQRPLPQ 331
           + G +    +    PP        SPLP  GKKP  P        ++N      ++P+P 
Sbjct: 224 ASGRNSGAWETKSPPPAAP-----SPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIP- 277

Query: 332 PALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPI 391
                                          A     SS  Q A   P F       PP 
Sbjct: 278 -------------------------------AERHRGSSHRQEAVQSPVF-------PPA 299

Query: 392 RAEGRNFPLPLPNKPRPPSPA----------------EEENSLNEEWYVSYITRPEAEAA 435
           + +    P+PLP      +P                 +E   L + WY     R  AE A
Sbjct: 300 QKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEA 359

Query: 436 LRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLRGKEDF 495
           L + N+DG+FL+R SS   +  PY L+V +  +VYNI +R+ + ++ Y LG    G+E F
Sbjct: 360 LHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYF 419

Query: 496 LSVSDIIDYFRKMPLLLIDGKN 517
            SV++II   +  PL+LID +N
Sbjct: 420 GSVAEIIRNHQHSPLVLIDSQN 441


>gi|166235901 B-cell linker isoform 2 [Homo sapiens]
          Length = 433

 Score =  127 bits (318), Expect = 3e-29
 Identities = 132/502 (26%), Positives = 187/502 (37%), Gaps = 122/502 (24%)

Query: 54  IQKFPKLRVPILSKLSQ------EINKNEE------RRSIFTRKPQVPRFPEETESHEED 101
           + K  K+ VP   KL Q      +I  NE       ++      P VPR    +ES  ++
Sbjct: 1   MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE 60

Query: 102 NGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSIL 161
              WS   + DYE+P++  D E    Y  P EE       D  YEPPP   E      + 
Sbjct: 61  EEQWSDDFDSDYENPDEHSDSE---MYVMPAEENA-----DDSYEPPPVEQE---TRPVH 109

Query: 162 PAKPFPNSNSMYIDR-------PPSGKT-PQQPPVPPQRPMAALPPPPAGRNHSPLPPPQ 213
           PA PF  +   YID        PP  KT P +P  P ++       P       P  PP+
Sbjct: 110 PALPF--ARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPK 167

Query: 214 TNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGR 273
                     +     +P    D +   P + S  P ++                   GR
Sbjct: 168 PK----GLLEDEADYVVPVEDNDENYIHPTESSSPPPEK-------------------GR 204

Query: 274 SLGEHLPKIQKPPLPPTTERHERSSPLP--GKKPPVPKHGWGPDRRENDEDDVHQRPLPQ 331
           + G    K   P  P         SPLP  GKKP  P        ++N      ++P+P 
Sbjct: 205 NSGAWETKSPPPAAP---------SPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIP- 254

Query: 332 PALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPI 391
                                          A     SS  Q A   P F       PP 
Sbjct: 255 -------------------------------AERHRGSSHRQEAVQSPVF-------PPA 276

Query: 392 RAEGRNFPLPLPNKPRPPSPA----------------EEENSLNEEWYVSYITRPEAEAA 435
           + +    P+PLP      +P                 +E   L + WY     R  AE A
Sbjct: 277 QKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEA 336

Query: 436 LRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLRGKEDF 495
           L + N+DG+FL+R SS   +  PY L+V +  +VYNI +R+ + ++ Y LG    G+E F
Sbjct: 337 LHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYF 396

Query: 496 LSVSDIIDYFRKMPLLLIDGKN 517
            SV++II   +  PL+LID +N
Sbjct: 397 GSVAEIIRNHQHSPLVLIDSQN 418


>gi|193083221 mast cell immunoreceptor signal transducer [Homo
           sapiens]
          Length = 428

 Score =  127 bits (318), Expect = 3e-29
 Identities = 119/399 (29%), Positives = 170/399 (42%), Gaps = 61/399 (15%)

Query: 142 DADYEPPPSNDEEALQN-SILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPP 200
           D DY+ P    EE  Q+  ILPA+P   S   Y D     K     P+P     +     
Sbjct: 66  DDDYDDPELRMEETWQSIKILPARPIKESE--YADTHYF-KVAMDTPLPLDTRTSISIGQ 122

Query: 201 PAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKK 260
           P     + L        +  RS+N K       +  R  K PL     P  R   TL KK
Sbjct: 123 PTWNTQTRLERVDKPISKDVRSQNIK-----GDASVRKNKIPL-----PPPRPLITLPKK 172

Query: 261 ------PPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGP 314
                  P S +P +    S     P++Q+  +P      + S  L  +K P        
Sbjct: 173 YQPLPPEPESSRPPL----SQRHTFPEVQR--MPSQISLRDLSEVLEAEKVP-------- 218

Query: 315 DRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQS 374
                     H +  P+   L  + NT             +P +    +F+ SN S    
Sbjct: 219 ----------HNQRKPESTHLLENQNT-----------QEIPLAISSSSFTTSNHSVQNR 257

Query: 375 ASLPPYFSQGPSN-RPPIRAEGRNFPLPLPNKP-RPPSP--AEEENSLNEEWYVSYITRP 430
                     P   +PP         LP      RPP P  ++ ++  + EWY+   +R 
Sbjct: 258 DHRGGMQPCSPQRCQPPASCSPHENILPYKYTSWRPPFPKRSDRKDVQHNEWYIGEYSRQ 317

Query: 431 EAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLR 490
             E A  K N+DG+FLVRD S K+   PYVL V Y++KVYN++IR+ + +Q + LGTGLR
Sbjct: 318 AVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFLERNQQFALGTGLR 377

Query: 491 GKEDFLSVSDIIDYFRKMPLLLIDGKNRGS--RYQCTLT 527
           G E F SV DII++++  P++LIDGK++    R QC LT
Sbjct: 378 GDEKFDSVEDIIEHYKNFPIILIDGKDKTGVHRKQCHLT 416


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 84.0 bits (206), Expect = 3e-16
 Identities = 80/280 (28%), Positives = 100/280 (35%), Gaps = 43/280 (15%)

Query: 151 NDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVP----------PQRPMAALPPP 200
           ND    +  +LP  P   S S     PPSG  P + PVP          PQR     P P
Sbjct: 119 NDSGGSRPPLLP--PGGRSTSAKPFSPPSG--PGRFPVPSPGHRSGPPEPQRNRMPPPRP 174

Query: 201 PAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKK 260
             G     +PPP  +   P +S  H     P P   R   P                   
Sbjct: 175 DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPG---------------PTP 219

Query: 261 PPFSDKPSIPAGRS------LGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGP 314
           PPF        G        L    P   +PPLPPT  R     P P   PP P      
Sbjct: 220 PPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP---PPPPV----- 271

Query: 315 DRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQS 374
             R +   +    P PQ    P+ S   PS S++  P  P PS   P     S+S   ++
Sbjct: 272 GNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDET 331

Query: 375 ASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEE 414
             LP       S+ PP+ + GR+ PLP P   RPP P  +
Sbjct: 332 PRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRD 371



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 50/184 (27%), Positives = 69/184 (37%), Gaps = 27/184 (14%)

Query: 139 VEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALP 198
           ++D     PPP  +  ++    +P  P  N+       P    + Q PP          P
Sbjct: 260 LDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP---------P 310

Query: 199 PPPAGRNHSPLPPPQTNHEEPSR------SRNHKTAKLPAPSIDRSTKPPLDRSLAPFDR 252
           PPP+     PLPP  + ++E  R      S +  T  LP+P       PP      P  R
Sbjct: 311 PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVR 370

Query: 253 EPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGW 312
           +P   G+  P    P +    S    LP    P LP    R    SP  G +PP+P    
Sbjct: 371 DP--PGRSGPLPPPPPVSRNGSTSRALP--ATPQLP---SRSGVDSPRSGPRPPLP---- 419

Query: 313 GPDR 316
            PDR
Sbjct: 420 -PDR 422



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 54/219 (24%), Positives = 86/219 (39%), Gaps = 28/219 (12%)

Query: 135 EEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPM 194
           E  P     + +PP  +      +S  P  P P S       PPS     + P  PQR +
Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNL 339

Query: 195 ---AALPPPPAGRNHSPLPPPQTNHEEPS-RSRNHKTAKLPAPSIDRSTKPPLDRSLAPF 250
              ++ PP P+     PLPPP +    P  R    ++  LP P       PP+ R+ +  
Sbjct: 340 SLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPP-------PPVSRNGSTS 392

Query: 251 DREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKH 310
              P T    P    +  + + RS         +PPLPP  +R    +P P       ++
Sbjct: 393 RALPAT----PQLPSRSGVDSPRS-------GPRPPLPP--DRPSAGAPPPPPPSTSIRN 439

Query: 311 GWGPDRREND-EDDVHQRP---LPQPALLPMSSNTFPSR 345
           G+     E++ E   +  P   LP P     ++ ++PS+
Sbjct: 440 GFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSK 478



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 39/118 (33%), Positives = 46/118 (38%), Gaps = 28/118 (23%)

Query: 131 PNEEEEAPVED----DADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQP 186
           P+E    PV D         PPP        +  LPA P   S S  +D P SG    +P
Sbjct: 361 PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRS-GVDSPRSG---PRP 416

Query: 187 PVPPQRPMAALPPPPAGRNHSPLPPPQTN-----------HEEPSRSRNHKTAKLPAP 233
           P+PP RP A  PPP         PPP T+            E  SR   H  + LP P
Sbjct: 417 PLPPDRPSAGAPPP---------PPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPP 465



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 52/170 (30%), Positives = 67/170 (39%), Gaps = 43/170 (25%)

Query: 131 PNEEEEAPVEDDADYEP-PPSNDEEALQNSILPAKPFPNSN--SMYIDRPPSGKTPQQPP 187
           P+   +AP        P PP     +  N   P  P  N +  S     P  G++   PP
Sbjct: 300 PSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPP 359

Query: 188 VPPQRPMAALPPP---PAGRNHSPLPPPQTNHEEPSRSRNHKTAK-LPA-PSIDRSTKPP 242
            P +RP    PPP   P GR+  PLPPP      P  SRN  T++ LPA P +   +   
Sbjct: 360 PPSERP----PPPVRDPPGRS-GPLPPP------PPVSRNGSTSRALPATPQLPSRSGVD 408

Query: 243 LDRSLAPFDREPFTLGKKPPF-SDKPSIPAGRSLGEHLPKIQKPPLPPTT 291
             RS           G +PP   D+PS  A             PP PP+T
Sbjct: 409 SPRS-----------GPRPPLPPDRPSAGA------------PPPPPPST 435


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 84.0 bits (206), Expect = 3e-16
 Identities = 80/280 (28%), Positives = 100/280 (35%), Gaps = 43/280 (15%)

Query: 151 NDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVP----------PQRPMAALPPP 200
           ND    +  +LP  P   S S     PPSG  P + PVP          PQR     P P
Sbjct: 119 NDSGGSRPPLLP--PGGRSTSAKPFSPPSG--PGRFPVPSPGHRSGPPEPQRNRMPPPRP 174

Query: 201 PAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKK 260
             G     +PPP  +   P +S  H     P P   R   P                   
Sbjct: 175 DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPG---------------PTP 219

Query: 261 PPFSDKPSIPAGRS------LGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGP 314
           PPF        G        L    P   +PPLPPT  R     P P   PP P      
Sbjct: 220 PPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP---PPPPV----- 271

Query: 315 DRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQS 374
             R +   +    P PQ    P+ S   PS S++  P  P PS   P     S+S   ++
Sbjct: 272 GNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDET 331

Query: 375 ASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEE 414
             LP       S+ PP+ + GR+ PLP P   RPP P  +
Sbjct: 332 PRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRD 371



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 50/184 (27%), Positives = 69/184 (37%), Gaps = 27/184 (14%)

Query: 139 VEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALP 198
           ++D     PPP  +  ++    +P  P  N+       P    + Q PP          P
Sbjct: 260 LDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP---------P 310

Query: 199 PPPAGRNHSPLPPPQTNHEEPSR------SRNHKTAKLPAPSIDRSTKPPLDRSLAPFDR 252
           PPP+     PLPP  + ++E  R      S +  T  LP+P       PP      P  R
Sbjct: 311 PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVR 370

Query: 253 EPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGW 312
           +P   G+  P    P +    S    LP    P LP    R    SP  G +PP+P    
Sbjct: 371 DP--PGRSGPLPPPPPVSRNGSTSRALP--ATPQLP---SRSGVDSPRSGPRPPLP---- 419

Query: 313 GPDR 316
            PDR
Sbjct: 420 -PDR 422



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 54/219 (24%), Positives = 86/219 (39%), Gaps = 28/219 (12%)

Query: 135 EEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPM 194
           E  P     + +PP  +      +S  P  P P S       PPS     + P  PQR +
Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNL 339

Query: 195 ---AALPPPPAGRNHSPLPPPQTNHEEPS-RSRNHKTAKLPAPSIDRSTKPPLDRSLAPF 250
              ++ PP P+     PLPPP +    P  R    ++  LP P       PP+ R+ +  
Sbjct: 340 SLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPP-------PPVSRNGSTS 392

Query: 251 DREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKH 310
              P T    P    +  + + RS         +PPLPP  +R    +P P       ++
Sbjct: 393 RALPAT----PQLPSRSGVDSPRS-------GPRPPLPP--DRPSAGAPPPPPPSTSIRN 439

Query: 311 GWGPDRREND-EDDVHQRP---LPQPALLPMSSNTFPSR 345
           G+     E++ E   +  P   LP P     ++ ++PS+
Sbjct: 440 GFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSK 478



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 39/118 (33%), Positives = 46/118 (38%), Gaps = 28/118 (23%)

Query: 131 PNEEEEAPVED----DADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQP 186
           P+E    PV D         PPP        +  LPA P   S S  +D P SG    +P
Sbjct: 361 PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRS-GVDSPRSG---PRP 416

Query: 187 PVPPQRPMAALPPPPAGRNHSPLPPPQTN-----------HEEPSRSRNHKTAKLPAP 233
           P+PP RP A  PPP         PPP T+            E  SR   H  + LP P
Sbjct: 417 PLPPDRPSAGAPPP---------PPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPP 465



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 52/170 (30%), Positives = 67/170 (39%), Gaps = 43/170 (25%)

Query: 131 PNEEEEAPVEDDADYEP-PPSNDEEALQNSILPAKPFPNSN--SMYIDRPPSGKTPQQPP 187
           P+   +AP        P PP     +  N   P  P  N +  S     P  G++   PP
Sbjct: 300 PSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPP 359

Query: 188 VPPQRPMAALPPP---PAGRNHSPLPPPQTNHEEPSRSRNHKTAK-LPA-PSIDRSTKPP 242
            P +RP    PPP   P GR+  PLPPP      P  SRN  T++ LPA P +   +   
Sbjct: 360 PPSERP----PPPVRDPPGRS-GPLPPP------PPVSRNGSTSRALPATPQLPSRSGVD 408

Query: 243 LDRSLAPFDREPFTLGKKPPF-SDKPSIPAGRSLGEHLPKIQKPPLPPTT 291
             RS           G +PP   D+PS  A             PP PP+T
Sbjct: 409 SPRS-----------GPRPPLPPDRPSAGA------------PPPPPPST 435


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 68/242 (28%), Positives = 84/242 (34%), Gaps = 21/242 (8%)

Query: 177 PPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSID 236
           P  G  PQ PP PP +P    PPP  G      PPP    + P     +K    P P   
Sbjct: 41  PQGGNKPQGPPSPPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 98

Query: 237 RSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHE- 295
           +   P  D+S +P        G  P   ++P  P         P   KP  PP    ++ 
Sbjct: 99  QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP--------PPPGKPQGPPPQGGNKP 150

Query: 296 RSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKP------ 349
           +  P PGK    P  G    R         Q P PQ    P      P +   P      
Sbjct: 151 QGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 210

Query: 350 SPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPP 409
            P  P P     G   + ++   QSA  PP   QGP   PP        P P P KP+ P
Sbjct: 211 KPQGPPPPGKPQGPPPQGDNK-SQSARSPPGKPQGP---PPQGGNQPQGPPPPPGKPQGP 266

Query: 410 SP 411
            P
Sbjct: 267 PP 268



 Score = 69.3 bits (168), Expect = 8e-12
 Identities = 77/296 (26%), Positives = 96/296 (32%), Gaps = 47/296 (15%)

Query: 122 GEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGK 181
           G+  G       + + P        PPP  D+     S  P KP           P  G 
Sbjct: 76  GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP-PGKPQGPP-------PQGGN 127

Query: 182 TPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKP 241
            PQ PP PP +P     PPP G N    PPP    + P    ++K+         RS++ 
Sbjct: 128 QPQGPPPPPGKPQG---PPPQGGNKPQGPPPPGKPQGPPPQGDNKS---------RSSRS 175

Query: 242 PLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLP 301
           P  +   P    P   G +P     P  P G+  G           PP      +  P P
Sbjct: 176 PPGKPQGP----PPQGGNQP---QGPPPPPGKPQGP----------PPQGGNKPQGPPPP 218

Query: 302 GKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKP------SPMNPL 355
           GK    P  G    +         Q P PQ    P      P +   P       P  P 
Sbjct: 219 GKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 278

Query: 356 PSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSP 411
           P     G   +  S    S S PP   QGP   PP        P P P KP+ P P
Sbjct: 279 PPGKPQGPPPQGGSKSRSSRS-PPGKPQGP---PPQGGNQPQGPPPPPGKPQGPPP 330



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 73/295 (24%), Positives = 93/295 (31%), Gaps = 53/295 (17%)

Query: 122 GEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGK 181
           G+  G       + + P        PPP  D ++  +   P KP           P  G 
Sbjct: 137 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPP-------PQGGN 189

Query: 182 TPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKP 241
            PQ PP PP +P     PPP G N    PPP    + P    ++K+    +P       P
Sbjct: 190 QPQGPPPPPGKPQG---PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPP 246

Query: 242 PLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLP 301
           P               G +P     P  P G+  G           PP      +  P P
Sbjct: 247 PQG-------------GNQP---QGPPPPPGKPQGP----------PPQGGNKPQGPPPP 280

Query: 302 GKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKP------SPMNPL 355
           GK    P  G    R         Q P PQ    P      P +   P       P  P 
Sbjct: 281 GKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 340

Query: 356 PSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPS 410
           P     G   +  S   +SA  PP   QGP  +     EG N     P  P PP+
Sbjct: 341 PPGKPQGPPPQGGSK-SRSARSPPGKPQGPPQQ-----EGNN-----PQGPPPPA 384



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 28/97 (28%), Positives = 36/97 (37%), Gaps = 8/97 (8%)

Query: 122 GEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPF----PNSNSMYIDRP 177
           G+  G       + + P        PPP    ++      P KP        N+     P
Sbjct: 323 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPP 382

Query: 178 PSGKTPQQPPVPPQ-RPMAALPPPPAGRNHSPLPPPQ 213
           P+G  PQQP  PP  +P     PP  GR   P  PPQ
Sbjct: 383 PAGGNPQQPQAPPAGQPQGPPRPPQGGR---PSRPPQ 416



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 42/160 (26%), Positives = 54/160 (33%), Gaps = 23/160 (14%)

Query: 265 DKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKK-----PPVPKHGWGPDRREN 319
           + PS+ AG   G       KP  PP+     +  P  G       PP P    GP  +  
Sbjct: 27  ESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 86

Query: 320 DEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPP 379
           ++      P       P    +   RS    P  P P             + PQ    PP
Sbjct: 87  NKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG----------GNQPQGPPPPP 136

Query: 380 YFSQGPSNRPPIRAEGRNFPL--PLPNKPRPPSPAEEENS 417
              QGP   PP   +G N P   P P KP+ P P  +  S
Sbjct: 137 GKPQGP---PP---QGGNKPQGPPPPGKPQGPPPQGDNKS 170



 Score = 33.5 bits (75), Expect = 0.50
 Identities = 41/162 (25%), Positives = 50/162 (30%), Gaps = 23/162 (14%)

Query: 85  KPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDAD 144
           KPQ P  P + +      G  S        SP     G+  G       + + P      
Sbjct: 273 KPQGPPPPGKPQGPPPQGGSKSRSSR----SP----PGKPQGPPPQGGNQPQGPPPPPGK 324

Query: 145 YEPPPSNDEEALQNSILPAKPF---PNSNSMYID-RPPSGKTPQQPPVPPQRPMAALPPP 200
            + PP       Q    P KP    P   S     R P GK PQ PP          PPP
Sbjct: 325 PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGK-PQGPPQQEGNNPQGPPPP 383

Query: 201 PAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPP 242
             G    P  PP    + P R           P   R ++PP
Sbjct: 384 AGGNPQQPQAPPAGQPQGPPR----------PPQGGRPSRPP 415


>gi|38348280 SH2 domain containing 6 [Homo sapiens]
          Length = 175

 Score = 73.2 bits (178), Expect = 6e-13
 Identities = 49/145 (33%), Positives = 72/145 (49%), Gaps = 2/145 (1%)

Query: 378 PPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALR 437
           PP     P     +  EGR   LP        S AE+ + L + WY     R   E+AL 
Sbjct: 21  PPPHPTPPQLNNLLLLEGRKSSLPSVAPTGSASAAEDSDLLTQPWYSGNCDRYAVESALL 80

Query: 438 KINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLRGKED-FL 496
            + +DG + VR SS    + P+ L VL + +V+NI IR     + Y LG   R +E+ F 
Sbjct: 81  HLQKDGAYTVRPSSGPHGSQPFTLAVLLRGRVFNIPIRRLDGGRHYALGREGRNREELFS 140

Query: 497 SVSDIIDYFRKMPLLLIDGKNRGSR 521
           SV+ ++ +F   PL L+D ++ GSR
Sbjct: 141 SVAAMVQHFMWHPLPLVD-RHSGSR 164


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 89/370 (24%), Positives = 133/370 (35%), Gaps = 46/370 (12%)

Query: 73  NKNEERRSIFTRKPQVPRFPEETESHEEDNGGW----SSFEEDDYESPNDDQDGEDDGDY 128
           +K  E+R   +  P+ PR  E +ES EED GG      S ++       + Q   D G  
Sbjct: 442 HKGTEKRESPSPAPK-PRKVELSES-EEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGS- 498

Query: 129 ESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPF-PNSNSMYIDRPPSGKTPQQPP 187
            S + E+E P            N E   +    P++   P+      +  P G+  + P 
Sbjct: 499 -SSSSEDERPKRSHV------KNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPS 551

Query: 188 VPP-QRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDR--------- 237
            PP +R  +  P PP  R  +P PPP+     P   R   + +  +P I R         
Sbjct: 552 PPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPK 611

Query: 238 ----STKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTER 293
               S  PP  R  +P       +   PP   + S P  +     L    +    P+   
Sbjct: 612 RRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSS-PVTKRRSPSLSSKHRKGSSPSRST 670

Query: 294 HERSSPLPGK------KPPVPKHGWGPDR-RENDEDDVHQRPLPQPALLP---MSSNTFP 343
            E  SP P K      +P  P+    P   R        +R  P P+  P   +S    P
Sbjct: 671 REARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 730

Query: 344 SRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLP----PYFSQGPSNR--PPIRAEGRN 397
            +  K +  +P     +  + S S S  P +   P    P  SQ PS    P +  +   
Sbjct: 731 KKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAK 790

Query: 398 FPLPLPNKPR 407
            P P P+ PR
Sbjct: 791 SPTPSPSPPR 800



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 68/340 (20%), Positives = 110/340 (32%), Gaps = 26/340 (7%)

Query: 84  RKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDA 143
           +K + P  PE +   +E +   ++   D  + P  +   E     + P+ E+ +  E + 
Sbjct: 216 KKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEP----KEPSPEKNSKKEKEK 271

Query: 144 DYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAG 203
           +   P S      ++      P                +P++ P P +RP      PP  
Sbjct: 272 EKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPP-- 329

Query: 204 RNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPF 263
               P PP       P R R   +A L   S   S+     RS +P  + P      P  
Sbjct: 330 -RRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSS----RSRSPPKKPPKRTSSPPRK 384

Query: 264 SDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDR---REND 320
           + + S  A      H P    P  PP   RH   +P    +    +    P R   +   
Sbjct: 385 TRRLSPSASPPRRRHRP--SPPATPPPKTRHS-PTPQQSNRTRKSRVSVSPGRTSGKVTK 441

Query: 321 EDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPY 380
                +R  P PA  P       S   K   M    S      +   N    Q +S    
Sbjct: 442 HKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQN----QQSSSDSG 497

Query: 381 FSQGPSNRPPIRAEGRNFPL-----PLPNKPRPPSPAEEE 415
            S    +  P R+  +N  +       P++   PSP + +
Sbjct: 498 SSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQ 537



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 58/242 (23%), Positives = 90/242 (37%), Gaps = 25/242 (10%)

Query: 204 RNHSPLPPPQTNHEEPSRS--RNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKP 261
           R+HS  P  +T    PS +  +  KT +LP PS+ +  +P +  + +  D       +  
Sbjct: 195 RSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSV-KVKEPSVQEATSTSDILKVPKPEPI 253

Query: 262 PFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKH-----GWGPDR 316
           P   +PS        +   K +      +  R    S  P    P  +H      + P R
Sbjct: 254 PEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRR 313

Query: 317 RENDEDDVHQRPLPQPALLPMSSNTFP--SRSTKPSPMNPLPSSHMPGAFSESNSSF--- 371
           R +      +RP P+    P      P   RS  P       S+ + G+ S S+SS    
Sbjct: 314 RPSP----RRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRS 369

Query: 372 -----PQSASLPPYFSQ--GPSNRPPIRAEGRNFPLPLPNKPR-PPSPAEEENSLNEEWY 423
                P+  S PP  ++   PS  PP R    + P   P K R  P+P +   +      
Sbjct: 370 PPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVS 429

Query: 424 VS 425
           VS
Sbjct: 430 VS 431


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 61/225 (27%), Positives = 81/225 (36%), Gaps = 19/225 (8%)

Query: 176 RPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSI 235
           RP  G  PQ+PP PP +P     PPP G N S  PPP     E    +    ++ P P  
Sbjct: 40  RPQGGNQPQRPPPPPGKPQG---PPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHP 96

Query: 236 DRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHE 295
            +  +PP           P      P   ++P    G       P   KP  PP    ++
Sbjct: 97  GKPERPPPQGGNQSQGTPP-----PPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQ 151

Query: 296 RSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKP-SPMNP 354
              P     PP P    GP  +E ++    + P  +P   P      P     P  P  P
Sbjct: 152 SQGP-----PPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGP 206

Query: 355 LPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFP 399
            P+   P       +  PQ    PP   QG   RPP  A+G+  P
Sbjct: 207 PPAGGNPQQPQAPPAGKPQGPPPPP---QG--GRPPRPAQGQQPP 246



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 51/207 (24%), Positives = 66/207 (31%), Gaps = 30/207 (14%)

Query: 132 NEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPF---PNSNSMYIDRPPSGKTPQQPP- 187
           N+ +  P        PPP    ++      P KP    P   +     PP    P++PP 
Sbjct: 45  NQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPP 104

Query: 188 --------VPPQRPMAALPPPPAGRNHSPLPPPQTNHEE-PSRSRNHKTAKLPAP----- 233
                    PP       PPP  G      PPP    E  P +  N      P P     
Sbjct: 105 QGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEG 164

Query: 234 ------SIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPL 287
                 +  RS + P  +   P  +E    G KP     P  P G       P  Q+P  
Sbjct: 165 PPPQEGNKSRSARSPPGKPQGPPQQE----GNKPQGPPPPGKPQGPPPAGGNP--QQPQA 218

Query: 288 PPTTERHERSSPLPGKKPPVPKHGWGP 314
           PP  +      P  G +PP P  G  P
Sbjct: 219 PPAGKPQGPPPPPQGGRPPRPAQGQQP 245



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 39/163 (23%), Positives = 53/163 (32%), Gaps = 30/163 (18%)

Query: 258 GKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLP--GKKPPVPKHGWGPD 315
           G++P   ++P  P         P   KP  PP    ++   P P  GK    P  G    
Sbjct: 38  GRRPQGGNQPQRPP--------PPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQS 89

Query: 316 RRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSA 375
           +         +RP PQ       +   P +  +P P     S   P              
Sbjct: 90  QGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPP-------------- 135

Query: 376 SLPPYFSQGPSNRPPIRAEGRNF-PLPLPNKPRPPSPAEEENS 417
             PP    G   RPP +   ++  P P P KP  P P E   S
Sbjct: 136 --PP---PGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKS 173


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 78/310 (25%), Positives = 101/310 (32%), Gaps = 46/310 (14%)

Query: 117 NDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDR 176
           N+D   E+     + N +  +P   +    PPP   +        P  P P   +     
Sbjct: 20  NEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGK--------PQGPPPQGGNKPQGP 71

Query: 177 PPSGKTPQQPPV----------PPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHK 226
           PP GK PQ PP           PP +P    PPP  G      PPP    + P     ++
Sbjct: 72  PPPGK-PQGPPPQGDKSRSPRSPPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNR 128

Query: 227 TAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPP 286
               P P   +   P  D+S +P        G  P   ++P  P         P   KP 
Sbjct: 129 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP--------PPPGKPQ 180

Query: 287 LPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRS 346
            PP     +   P P  KP  P       R         Q P PQ    P      P + 
Sbjct: 181 GPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKP 240

Query: 347 TKP------SPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPL 400
             P       P  P P     G  ++  S   QSA  PP   QGP  +     EG N   
Sbjct: 241 QGPPPQGGNKPQGPPPPGKPQGPPAQGGSK-SQSARSPPGKPQGPPQQ-----EGNN--- 291

Query: 401 PLPNKPRPPS 410
             P  P PP+
Sbjct: 292 --PQGPPPPA 299



 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 64/241 (26%), Positives = 77/241 (31%), Gaps = 42/241 (17%)

Query: 177 PPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSID 236
           P  G  PQ PP PP +P     PPP G N    PPP                    P   
Sbjct: 41  PQGGNKPQGPPPPPGKPQG---PPPQGGNKPQGPPP--------------------PGKP 77

Query: 237 RSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHER 296
           +   P  D+S +P        G  P   ++P  P         P   KP  PP    +  
Sbjct: 78  QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP--------PPPGKPQGPPPQGGNRP 129

Query: 297 SSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKP------S 350
             P P  KP  P       R         Q P PQ    P      P +   P       
Sbjct: 130 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK 189

Query: 351 PMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPS 410
           P  P P     G   + + S  +S+  PP   QGP   PP        P P P KP+ P 
Sbjct: 190 PQGPPPPGKPQGPPPQGDKS--RSSQSPPGKPQGP---PPQGGNQPQGPPPPPGKPQGPP 244

Query: 411 P 411
           P
Sbjct: 245 P 245



 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 77/300 (25%), Positives = 95/300 (31%), Gaps = 55/300 (18%)

Query: 122 GEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGK 181
           G+  G       + + P        PPP  D+     S  P KP           P  G 
Sbjct: 55  GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP-PGKPQGPP-------PQGGN 106

Query: 182 TPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEP------SRSRNHKTAKLPAP-- 233
            PQ PP PP +P     PPP G N    PPP    + P      SRS      K   P  
Sbjct: 107 QPQGPPPPPGKPQG---PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 163

Query: 234 ---SIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAG--------RSLGEHLPKI 282
              +  +   PP  +   P    P   GKKP     P  P G        RS      K 
Sbjct: 164 QGGNQPQGPPPPPGKPQGP----PPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKP 219

Query: 283 QKPPL---------PPTTERHERSSPLPGKKP---PVPKHGWGPDRRENDEDDVHQRPLP 330
           Q PP          PP   + +   P  G KP   P P    GP  +   +    + P  
Sbjct: 220 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPG 279

Query: 331 QPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPP 390
           +P   P      P     P+  NP      P       +  PQ    PP    G  +RPP
Sbjct: 280 KPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP-------AGQPQGPPRPP--QGGRPSRPP 330



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 43/160 (26%), Positives = 51/160 (31%), Gaps = 19/160 (11%)

Query: 258 GKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRR 317
           G  P   +KP  P         P   KP  PP    ++   P P  KP  P       R 
Sbjct: 38  GPSPQGGNKPQGPP--------PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRS 89

Query: 318 ENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMN------PLPSSHMPGAFSESNSSF 371
                   Q P PQ    P      P +   P P        P P     G   + + S 
Sbjct: 90  PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKS- 148

Query: 372 PQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSP 411
            +S   PP   QGP   PP        P P P KP+ P P
Sbjct: 149 -RSPRSPPGKPQGP---PPQGGNQPQGPPPPPGKPQGPPP 184



 Score = 36.2 bits (82), Expect = 0.077
 Identities = 27/97 (27%), Positives = 35/97 (36%), Gaps = 8/97 (8%)

Query: 122 GEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPF----PNSNSMYIDRP 177
           G+  G       + + P        PP     ++      P KP        N+     P
Sbjct: 238 GKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPP 297

Query: 178 PSGKTPQQPPVPPQ-RPMAALPPPPAGRNHSPLPPPQ 213
           P+G  PQQP  PP  +P     PP  GR   P  PPQ
Sbjct: 298 PAGGNPQQPQAPPAGQPQGPPRPPQGGR---PSRPPQ 331



 Score = 32.7 bits (73), Expect = 0.85
 Identities = 38/155 (24%), Positives = 57/155 (36%), Gaps = 24/155 (15%)

Query: 268 SIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKP----PVPKHGWGPDRRENDEDD 323
           ++ + ++L E + + + P L       +  SP  G KP    P P    GP  +  ++  
Sbjct: 12  ALSSAQNLNEDVSQEESPSL--IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQ 69

Query: 324 VHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQ 383
               P       P    +   RS    P  P P             + PQ    PP   Q
Sbjct: 70  GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG----------GNQPQGPPPPPGKPQ 119

Query: 384 GPSNRPPIRAEGRNFPL--PLPNKPRPPSPAEEEN 416
           GP   PP   +G N P   P P KP+ P P  +++
Sbjct: 120 GP---PP---QGGNRPQGPPPPGKPQGPPPQGDKS 148


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 86/342 (25%), Positives = 129/342 (37%), Gaps = 52/342 (15%)

Query: 131 PNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPP 190
           P E   +P  +++   PPP     +     LPA P P +  +++ RP   ++P  PP P 
Sbjct: 444 PEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEA--LHLSRPLE-ESPLSPP-PE 499

Query: 191 QRPMAALPPPPAGR----NHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRS 246
           + P++  PPP +        SPL PP+   E P           P+P+++    PP + S
Sbjct: 500 ESPLS--PPPESSPFSPLEESPLSPPE---ESP-----------PSPALETPLSPPPEAS 543

Query: 247 LAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP 306
                  P +    PPF + P  P    L    P       PP  E     SP P + P 
Sbjct: 544 -------PLS----PPFEESPLSPPPEELPTSPPPEASRLSPPPEE--SPMSPPPEESPM 590

Query: 307 VPKHGWGPDRRENDEDDVHQRPL-PQPALLPMSSNTFPSRSTKP---SPMNPLP--SSHM 360
            P     P           + PL P P   P+S     SR + P   SPM+P P  S   
Sbjct: 591 SP-----PPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMS 645

Query: 361 PGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFP----LPLPNKPRPPSPAEEEN 416
           P       S  P  + L P   + P + PP  +     P    L  P +  P SP  E++
Sbjct: 646 PPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDS 705

Query: 417 SLNEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNP 458
             +     S ++ P  E+ L  + ++     R      +  P
Sbjct: 706 PASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRP 747



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 82/306 (26%), Positives = 110/306 (35%), Gaps = 45/306 (14%)

Query: 149  PSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPV--PPQRPMAALP------PP 200
            PS D   L  +      FP +   Y   P     P QPP+     RP A  P      PP
Sbjct: 2172 PSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPP 2231

Query: 201  PAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKP-----PLDRSLAPFDREPF 255
               R+    P P      PS   N    + P     ++++P     P   S    + +  
Sbjct: 2232 GTPRHQPSTPDPFLKPRCPSLD-NLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKE 2290

Query: 256  TLGKKPPFSDKPSIPA--GRSLGEHL-------PKIQKPPLPPTTERHERSSPLPGKKP- 305
             LG   P    P++      S G HL       P + K PL P   + E  SP  G +P 
Sbjct: 2291 ELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQ 2350

Query: 306  -PVPKHGWGPDRRENDE--------DDVHQRPL---PQPALLPMSSNTFPSRSTKPSPMN 353
             P P     P    + +        D   Q PL   PQP   P S    P RS    P +
Sbjct: 2351 EPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP-PESCCALPPRSLPSDPFS 2409

Query: 354  PLPSSHMPGAFSESN--------SSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNK 405
             +P+S    + S+S          +F  S   P + S  P +RPP R + R+   PL   
Sbjct: 2410 RVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKP 2469

Query: 406  PRPPSP 411
            PRP  P
Sbjct: 2470 PRPQPP 2475



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 75/290 (25%), Positives = 106/290 (36%), Gaps = 35/290 (12%)

Query: 131 PNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPP 190
           P     +P+E+     P  S    AL+  + P  P  +  S   +  P    P++ P  P
Sbjct: 507 PESSPFSPLEESPLSPPEESPPSPALETPLSPP-PEASPLSPPFEESPLSPPPEELPTSP 565

Query: 191 QRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPF 250
               + L PPP     SP+ PP    EE   S   + ++L  P  +    PP + S  P 
Sbjct: 566 PPEASRLSPPPEE---SPMSPPP---EESPMSPPPEASRLFPPFEESPLSPPPEES--PL 617

Query: 251 DREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLP---GKKPPV 307
              P      PP  D P  P         P  + P  PP      R SPLP      PP 
Sbjct: 618 SPPPEASRLSPPPEDSPMSP---------PPEESPMSPP--PEVSRLSPLPVVSRLSPPP 666

Query: 308 PKHGWGPDRRENDEDDVHQRPLPQPA-LLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSE 366
            +    P   E+        P P+ + L P   ++  S   + SP +P P   +     E
Sbjct: 667 EESPLSPPPEESPTS-----PPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLE 721

Query: 367 SNS--SFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEE 414
            +     P+   L P  S+GP   P  R E  +   P P +P     AEE
Sbjct: 722 ESPLLPLPEEPQLCPR-SEGPHLSP--RPEEPHLS-PRPEEPHLSPQAEE 767



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 82/331 (24%), Positives = 114/331 (34%), Gaps = 56/331 (16%)

Query: 130 SPNEEEEAPVED-DADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKT----PQ 184
           SP E  + P ++ DA Y       +     S+ P +P P    +  +  P GK       
Sbjct: 373 SPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGP----LQCEAKPLGKAGVQLEP 428

Query: 185 QPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLD 244
           Q   P    M  LPPP      SPL PP                    P    ++ PP  
Sbjct: 429 QLEAPLNEEMPLLPPP----EESPLSPP--------------------PEESPTSPPPEA 464

Query: 245 RSLAPFDRE------PFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSS 298
             L+P   E      P  L    P  + P  P      E  P    P   P +   E   
Sbjct: 465 SRLSPPPEELPASPLPEALHLSRPLEESPLSPP----PEESPLSPPPESSPFSPLEESPL 520

Query: 299 PLPGKKPPVPKHGW---GPDRRENDEDDVHQRPL-PQPALLPMSSNTFPSRSTKP---SP 351
             P + PP P        P           + PL P P  LP S     SR + P   SP
Sbjct: 521 SPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESP 580

Query: 352 MNPLPSSHMPGAFSESNSSFP--QSASLPPYFSQGPSNRPP----IRAEGRNFPLPLPNK 405
           M+P P         E++  FP  + + L P   + P + PP    +     + P+  P +
Sbjct: 581 MSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPE 640

Query: 406 PRPPSPAEEENSLNEEWYVSYITRPEAEAAL 436
             P SP  E + L+    VS ++ P  E+ L
Sbjct: 641 ESPMSPPPEVSRLSPLPVVSRLSPPPEESPL 671



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 82/325 (25%), Positives = 123/325 (37%), Gaps = 52/325 (16%)

Query: 130  SPNEEEE--APVEDDADYEPPPSNDEEALQNS--ILPAKPFPNSNSMYIDRPPSGKTPQQ 185
            SP  EE   +PV ++    P P     + Q+    L  +P  +  S  +++PP    P++
Sbjct: 807  SPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEK 866

Query: 186  PPVPPQRPMA----ALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPS---IDRS 238
            PP  P +  A     L PPP   + SPL        EP+ S   +    P P    +  S
Sbjct: 867  PPEEPGQCPAPEELPLFPPPGEPSLSPL------LGEPALSEPGEPPLSPLPEELPLSPS 920

Query: 239  TKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGE-----------------HLPK 281
             +P L   L P D  P  L    P     + PA   LGE                   P 
Sbjct: 921  GEPSLSPQLMPPDPLPPPLS---PIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPI 977

Query: 282  IQKPPLPPTTERHERSSPLPGK-KPPVPKHGWGPDRRENDEDDVHQ-RPLPQPALLPMSS 339
            ++ P  PP         P+P    PP P    GP      E    Q  PL Q +L+P   
Sbjct: 978  LETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVP--Q 1035

Query: 340  NTFPSRSTK-------PSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIR 392
            N+ PS+ +        PSP++P+         +E +    +  S P   +  PS   P+ 
Sbjct: 1036 NSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLP 1095

Query: 393  AEGRNFPLPLPNKPRPPSPAEEENS 417
            +   +   P P+    P+PA ++ S
Sbjct: 1096 SPMGDLSCPAPS----PAPALDDFS 1116



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 51/182 (28%), Positives = 73/182 (40%), Gaps = 25/182 (13%)

Query: 166  FPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNH 225
            FP   +  +    +G  PQ PP  P  P A    P  G  H P PPP ++ +EP R    
Sbjct: 4266 FPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVH-PTPPP-SSPQEPKR---- 4319

Query: 226  KTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPS---IPAGRSLGEHLPKI 282
              ++LP+P    S++ P +  L P    P T   + P  + P     PA   L + L   
Sbjct: 4320 -PSQLPSP----SSQLPTEAQLPP--THPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSK 4372

Query: 283  QKPPLPP-----TTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPM 337
               P  P      T++ E+SS +PG    V     G    E  +  + Q P  +P  L  
Sbjct: 4373 GLGPWDPPDNLAETQKPEQSSLVPGHLDQVN----GQVVPEASQLSIKQEPREEPCALGA 4428

Query: 338  SS 339
             S
Sbjct: 4429 QS 4430



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 29/106 (27%), Positives = 40/106 (37%), Gaps = 20/106 (18%)

Query: 204  RNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPF 263
            +  SP P P T H       N    +L AP  +  + PP    LAP    P T     P 
Sbjct: 4880 KQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPP--SPLAPSPASPPT----EPL 4933

Query: 264  SDKPSIPAGRSLGEHLPKIQKPPLP---PTTERHERSSPLPGKKPP 306
             + P+ P           + +PP+P   P     E + P P  +PP
Sbjct: 4934 VELPTEP-----------LAEPPVPSPLPLASSPESARPKPRARPP 4968



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 35/118 (29%), Positives = 44/118 (37%), Gaps = 19/118 (16%)

Query: 288  PPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQ-PALLPMSSNTF---- 342
            PP  E   ++SPL G     P+ G  P  +     ++   P PQ P  LP          
Sbjct: 4241 PPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGP 4300

Query: 343  ---PSRSTKP--SPMNPLPSSHMPGAFSESNSSFPQSASLPPYF-----SQGPSNRPP 390
               P   T P  SP  P   S +P      +S  P  A LPP        QGP+  PP
Sbjct: 4301 VLGPVHPTPPPSSPQEPKRPSQLP----SPSSQLPTEAQLPPTHPGTPKPQGPTLEPP 4354



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 5/66 (7%)

Query: 177  PPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSID 236
            PPS   P  P  PP  P+  LP  P      P+P P      P  +R    A+ P    D
Sbjct: 4917 PPSPLAPS-PASPPTEPLVELPTEPLA--EPPVPSPLPLASSPESARPKPRARPPEEGED 4973

Query: 237  RSTKPP 242
              ++PP
Sbjct: 4974 --SRPP 4977



 Score = 29.6 bits (65), Expect = 7.2
 Identities = 69/268 (25%), Positives = 94/268 (35%), Gaps = 59/268 (22%)

Query: 147  PPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPM------------ 194
            P P + E    + + P    P+  S    RP S + P  P   P RP             
Sbjct: 2427 PRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQS-RDPFAPLHKPPRPQPPEVAFKAGSLA 2485

Query: 195  ----------AALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKT-AKLPAPSIDRSTKPPL 243
                      AALP  PAG  H+ +P  Q     P+  R+  T A +  PS  R T P  
Sbjct: 2486 HTSLGAGGFPAALPAGPAGELHAKVPSGQ----PPNFVRSPGTGAFVGTPSPMRFTFPQA 2541

Query: 244  --DRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPL- 300
              + SL P   +P   G  PP         G +LG+  P+     +  T   H   SPL 
Sbjct: 2542 VGEPSLKPPVPQP---GLPPPHGINSHFGPGPTLGK--PQSTNYTV-ATGNFHPSGSPLG 2595

Query: 301  PGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPA---LLPMSSNTFPSRSTKPSPM----- 352
            P        +G  P R  +         LP PA    LP  S+    RS   SP+     
Sbjct: 2596 PSSGSTGESYGLSPLRPPS--------VLPPPAPDGSLPYLSHGASQRSGITSPVEKRED 2647

Query: 353  ------NPLPSSHMPGAFSESNSSFPQS 374
                  + L ++ +PG      S   Q+
Sbjct: 2648 PGTGMGSSLATAELPGTQDPGMSGLSQT 2675



 Score = 29.6 bits (65), Expect = 7.2
 Identities = 22/79 (27%), Positives = 29/79 (36%), Gaps = 19/79 (24%)

Query: 131  PNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPP 190
            P      PV       PPPS+ +E  + S LP+              PS + P +  +PP
Sbjct: 4293 PGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPS--------------PSSQLPTEAQLPP 4338

Query: 191  QRPMAALP-----PPPAGR 204
              P    P      PP GR
Sbjct: 4339 THPGTPKPQGPTLEPPPGR 4357



 Score = 29.3 bits (64), Expect = 9.4
 Identities = 36/126 (28%), Positives = 43/126 (34%), Gaps = 20/126 (15%)

Query: 297  SSPLPGKKPPVPKHGWGP----DRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPM 352
            S+ LPG   PVP    GP    + R N +  +     P P   P     F   S  P  +
Sbjct: 2858 STRLPGPGEPVPGPA-GPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRL 2916

Query: 353  NP-----LPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPR 407
             P     L  S +P          PQ  S PP      S  P    +G   P  L    R
Sbjct: 2917 APEGLRGLAVSGLP----------PQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNR 2966

Query: 408  PPSPAE 413
            PPS  E
Sbjct: 2967 PPSSTE 2972


>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
          Length = 2063

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 79/326 (24%), Positives = 118/326 (36%), Gaps = 57/326 (17%)

Query: 141  DDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPP-------VPPQRP 193
            ++AD  P P      L NS      F N    Y  +P   +  QQ P        PP +P
Sbjct: 941  EEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQP 1000

Query: 194  MAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDRE 253
                P P   +   P PP Q   ++  + +      L      +S + P+ +++ P  R 
Sbjct: 1001 PQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHP-PRG 1059

Query: 254  PFTL-GKKPPFSDKPSIPA-----GRSLGEHLPKIQKPPLPPTTERHERS-------SPL 300
            P     ++ P     S+P      G +     P  Q+ P+P  T     S       SP 
Sbjct: 1060 PLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQ 1119

Query: 301  PGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPS---------- 350
                 P+ +    P+   ++   V   P   P+ + +  N       KP           
Sbjct: 1120 NPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGA 1179

Query: 351  -----PMNPLPSS---HMPGAFSESNSSFPQS---ASLPPYFSQGPSNRPP--------I 391
                 P+N LPSS   H P   + + +S P++   AS  PY+ Q P+NRPP        +
Sbjct: 1180 TPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISL 1239

Query: 392  RAEGRN------FPLPLPNKPRPPSP 411
              E  N      FP P  N P PP P
Sbjct: 1240 SPERLNASIAGLFP-PQINIPLPPRP 1264



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 52/227 (22%), Positives = 76/227 (33%), Gaps = 43/227 (18%)

Query: 178 PSGKTPQQPPVPP---QRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPS 234
           P    P Q PVPP   Q P  AL PPPA          Q +    + ++  K A LP P 
Sbjct: 304 PQFTAPTQVPVPPGWNQLPSGALQPPPA----------QGSLGTMTANQGWKKAPLPGPM 353

Query: 235 IDR-STKPPLDRSLAP-FDREPFTLGKKPPFSDKPSIPA----GRSLGEHLPKIQKPP-- 286
             +   +P L     P     P+  G +       + P     G+     +  +Q  P  
Sbjct: 354 QQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSR 413

Query: 287 LPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRS 346
           +P   ++   ++  P   P   + G                    PA  P  + T     
Sbjct: 414 VPTPLQQPHLTNKSPASSPSSFQQG-------------------SPASSPTVNQTQQQMG 454

Query: 347 TKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYF---SQGPSNRPP 390
            +P   NPLP        S   +   Q  ++PP F    Q P N+ P
Sbjct: 455 PRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGP 501



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 33/136 (24%), Positives = 55/136 (40%), Gaps = 14/136 (10%)

Query: 157  QNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNH 216
            Q S +PA P   ++ +    PPS        +P     ++ P PP   + SP P  QT  
Sbjct: 1674 QPSTIPAAPLTTNSGLM---PPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGR 1730

Query: 217  EEPSRSRNHKTAKLPAPSIDRS----TKPPLD--RSLAPFDREPFTLGKKPPFSDKPSIP 270
                 SR     +LP+P    S    + PP+   + L P +  P    +    +D+ ++P
Sbjct: 1731 PLVLSSR-ATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASP----QVNTSADQNTLP 1785

Query: 271  AGRSLGEHLPKIQKPP 286
            + +S     P +   P
Sbjct: 1786 SSQSTTMVSPLLTNSP 1801


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 83/315 (26%), Positives = 107/315 (33%), Gaps = 54/315 (17%)

Query: 131 PNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPP 190
           P+     P E  +    PP     AL +  L   P P  + +    PP    PQ PP   
Sbjct: 573 PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLAT--PP----PQAPPXLA 626

Query: 191 QRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPF 250
             P+ A P PPA    SPL  P             +    P PS      PP+    +P 
Sbjct: 627 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS------PPVQAPFSPP 680

Query: 251 DREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP---V 307
              P +    PP    PS+ A        P +Q PP PP +     S+  P + PP    
Sbjct: 681 ASPPVSPSATPPSQAPPSLAA--------PPLQVPPSPPASPPMSPSATPPPQAPPPLAA 732

Query: 308 PKHGWGPDRRENDEDDVHQRPLPQ----------------PALLPMSSNTFPSRSTKPS- 350
           P     P    +        P P+                PA LPMS    P     P+ 
Sbjct: 733 PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792

Query: 351 ---PMNPLPSSHMPGAFSESNSSFPQSASLP--PYFSQGPSNRPPIRAEGRNFPLPLPNK 405
              P+  LPS   P A     + F  SASLP  P  +  P   P + A     P   P  
Sbjct: 793 ATPPLQALPS---PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 849

Query: 406 P------RPPSPAEE 414
           P      RPP+P  +
Sbjct: 850 PTLQAPRRPPTPGPD 864



 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 77/299 (25%), Positives = 106/299 (35%), Gaps = 37/299 (12%)

Query: 131 PNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPP 190
           P  E ++ +   +   PP S     L+N    A P   + S  +  P     P   P P 
Sbjct: 510 PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL 569

Query: 191 QRPMAAL-PPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDR---- 245
           Q P + L  PPP   +    PPPQ     P    +     LP+P +     PP       
Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQA----PPALASPPLQGLPSPPLSPLATPPPQAPPXL 625

Query: 246 SLAPFDREPFTLGKKPPFSD--KPSIPAGRSLGEHL----------PKIQKPPLPPTTER 293
           +L P    P +    PP S    PS  A  +L  HL          P +Q P  PP +  
Sbjct: 626 ALPPLQAPP-SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 684

Query: 294 HERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMS-SNTFPSRSTKPSPM 352
              S+  P + PP            +      Q P   PA  PMS S T P ++  P   
Sbjct: 685 VSPSATPPSQAPP------------SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 732

Query: 353 NPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSP 411
            PL     P A    + S      +PP  +  P   PP  +   + P+    KP P +P
Sbjct: 733 PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP--SPPASLPMSPLAKPPPQAP 789



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 75/302 (24%), Positives = 106/302 (35%), Gaps = 53/302 (17%)

Query: 162 PAKPF-PNSNSMYIDRPPSGKTPQQPPVPPQRPMAALP---PPPAGRNHSPLPPPQTNHE 217
           PA P  P    +   RPP    P++   P   P+++ P   P P+G    P+PPP  N  
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD-NAA 324

Query: 218 EPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFT-LGKKPPFSDKPSIPAGRSL- 275
            P  +    +  L  P       P    SL      P T   + PP    P + A  SL 
Sbjct: 325 TPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQ 384

Query: 276 ---------GEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGW-------------G 313
                        P +Q PP P      + ++ L G       H +              
Sbjct: 385 TIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL-GSPTLQATHSFLTMSPRQTQASLTS 443

Query: 314 PDRRENDEDDVH--QRPLPQPALLPMSSNTFPSRSTKPSPMNPLP-------SSHMPGAF 364
           P R  +   D    Q PL  PA  P+ ++  P+ S   SP+   P       +SH P A 
Sbjct: 444 PSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAP 503

Query: 365 SESNSSFP---QSASLPPYFSQGPSN--RPPIR---------AEGRNFPLPLPNKPRPPS 410
             S    P   QS+  PP     P++   PP+           +  + PL  P+   PP 
Sbjct: 504 LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPC 563

Query: 411 PA 412
           PA
Sbjct: 564 PA 565



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 78/308 (25%), Positives = 101/308 (32%), Gaps = 52/308 (16%)

Query: 130 SPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVP 189
           SP+  +  PV       PPP N    L  ++ P+ P      +    P +  + Q  P P
Sbjct: 308 SPSGTKARPV-------PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360

Query: 190 PQRPMAALPP----PP--AGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRST---K 240
           P  P +  PP    PP  A  +   +PP Q  H   S S     + L   S+  +T    
Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420

Query: 241 PPL--------------DRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHL-PKIQKP 285
           P L                SL    R   T    PP     S+PA   L   L P +   
Sbjct: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480

Query: 286 PLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPL-PQPALLPMSSNTFPS 344
             P T    +  S L    P  P               +   PL  Q +L P S  T P+
Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPL------------SSLIMPPLETQSSLAPPSLQTPPA 528

Query: 345 RSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPN 404
             T P P+  LPS   P   + S          PP  +  P   PP        PL  P 
Sbjct: 529 SLTTP-PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP-------SPLTTPP 580

Query: 405 KPRPPSPA 412
              P S A
Sbjct: 581 PETPSSIA 588



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 45/185 (24%), Positives = 65/185 (35%), Gaps = 34/185 (18%)

Query: 148 PPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVP--------PQRPMAALPP 199
           PP      L   +L   P P ++       P+ + P++PP P        P+  +A  P 
Sbjct: 827 PPPQAPPVLAAPLLQVPPSPPAS-------PTLQAPRRPPTPGPDTSVSGPRLTLALAPG 879

Query: 200 PPAGRNHSPLP----PPQTNHEEPSRSRNHKTAKLPA-PSIDRSTKPPLDRSLAPFDREP 254
           PP   + SP      P    H   + S   +     + P    +  PP D  LA      
Sbjct: 880 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 939

Query: 255 FTLGKKPP--FSDKPSIP------AGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP 306
           ++ G  PP  F   P  P       G    + L  I +      TE  E ++P PG   P
Sbjct: 940 WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE------TEGPESATPAPGALDP 993

Query: 307 VPKHG 311
            P  G
Sbjct: 994 GPSPG 998


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 77/355 (21%), Positives = 118/355 (33%), Gaps = 29/355 (8%)

Query: 73  NKNEERRSIFTRKPQVPRF---PEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYE 129
           NK      I T KP  PR    P    S E           +  E+   ++    DG  +
Sbjct: 110 NKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK 169

Query: 130 SPNEEEEAPVEDDADYEPPPSND------EEALQNSILPAKPFPNSNSMYIDRPPSGKTP 183
           + + +E   +E  +  +  P++        +A   +  PA   P   +    + P+  TP
Sbjct: 170 TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP 229

Query: 184 QQPPVP-----PQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRS 238
           ++P        P  P    P        +P  P  T  +EP+ +    T K PAP+  + 
Sbjct: 230 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT----TPKEPAPTTTKE 285

Query: 239 TKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSS 298
             P   +S     +EP     K P    P  PA  +  E  P   K P P T E     +
Sbjct: 286 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE----PA 341

Query: 299 PLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSS 358
           P   K+P        P   +       + P P     P  + T     T P    P  + 
Sbjct: 342 PTTPKEP-------APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 394

Query: 359 HMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAE 413
             P    E   +  +SA   P      + + P     +      P KP P +P E
Sbjct: 395 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 449



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 66/294 (22%), Positives = 99/294 (33%), Gaps = 36/294 (12%)

Query: 146 EPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRN 205
           EP P+  + A      P +P P +      + P+  TP++P      P     P P    
Sbjct: 246 EPAPTTTKSA---PTTPKEPAPTTT-----KEPAPTTPKEPA-----PTTTKEPAPTTTK 292

Query: 206 HSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSD 265
            +P  P +     P +     T K PAP+  +   P   +  AP  +EP     K P   
Sbjct: 293 SAPTTPKEPAPTTPKKPAP-TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 351

Query: 266 KPSIPAGRSLGEHLPKIQKPPLPPTTERHE------------RSSPLPGKKPPVPKHGWG 313
            P  PA  +  E  P   K P P TT+               +S+P   K+P        
Sbjct: 352 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 411

Query: 314 PDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQ 373
           P   +       + P P     P  + T P +    +P  P P++    A + +    P 
Sbjct: 412 PTTPKEPSPTTTKEPAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 469

Query: 374 SASLPPYFSQGPSNRPPIRAEGRNFPLP------LPNKPRPPSPAEEENSLNEE 421
           +   P      P    P   +      P       P KP P +P E   +  EE
Sbjct: 470 TPKEPA--PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 521



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 78/354 (22%), Positives = 119/354 (33%), Gaps = 53/354 (14%)

Query: 130 SPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQP-PV 188
           +P   + AP       EP P+  +E       PA   P   +    + P+  TP++P P 
Sbjct: 404 APTTTKSAPTTPK---EPSPTTTKE-------PAPTTPKEPAPTTPKKPAPTTPKEPAPT 453

Query: 189 PPQRPMAAL---PPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDR 245
            P+ P       P P   +  +P  P +T    P +       KL AP+      P    
Sbjct: 454 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL-APTTPEKPAPTTPE 512

Query: 246 SLAPFD-REPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKK 304
            LAP    EP     + P    P   A  +  E  P   K P P T +  E +   P + 
Sbjct: 513 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--EPAPTTPKET 570

Query: 305 PPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSS-----------------NTFPSRST 347
            P    G  P   +       ++P P+  L P ++                  T P+   
Sbjct: 571 APTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 629

Query: 348 KPSPMNP------LPSSHMPGAFSESNSSFPQSAS---LPPYFSQGP----SNRPPIRAE 394
           +P+P  P       P    P    E   + P+  +   L P  ++GP    S++P     
Sbjct: 630 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 689

Query: 395 GRNFPL----PLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALRKINQDGT 444
               P     P P  P+ P+P   E        VS  T  +    + K   + T
Sbjct: 690 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 743



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 71/280 (25%), Positives = 96/280 (34%), Gaps = 52/280 (18%)

Query: 162 PAKPFPNSNSMYIDRPPSGKTPQQPPVP-PQRPMAALPPPPAGRNHSPLPPPQTNHEEPS 220
           P KP P +        P   TP  P  P P  P AA P       ++P  P  T  +EP+
Sbjct: 503 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-------NTPKEPAPTTPKEPA 555

Query: 221 RSRNHKTAKLPAPSIDRSTKPPLDRSLAPFD-REPF-TLGKKP------------PFS-- 264
            +    T K PAP+  + T P   +  AP   +EP  T  KKP            P S  
Sbjct: 556 PT----TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 611

Query: 265 -DKPSIPAGRSLGEHLPKIQKPPLP----PTTERHERSSPLPGKKPPVPKHGW------- 312
            DKP+    +      PK   P  P    PTT +    + L    P  PK          
Sbjct: 612 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 671

Query: 313 ---GPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNS 369
              GP    +D+        P P     ++ T P      +P  P P++      + S  
Sbjct: 672 TTKGPTSTTSDK--------PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 723

Query: 370 SFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPP 409
           S P +   P    + P    P        P  L N P+ P
Sbjct: 724 STPTTTKEPTTIHKSPDESTP-ELSAEPTPKALENSPKEP 762



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 43/203 (21%), Positives = 69/203 (33%), Gaps = 38/203 (18%)

Query: 162 PAKPFPNSNSMYIDRPPSGKTPQQP---------PVPPQRPMAALPPPPAG--------- 203
           P KP P   +    + P+  T  +P         P  P+ P    P  PA          
Sbjct: 591 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 650

Query: 204 --RNHSPLPPPQTNHEE----PSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDRE---P 254
             +  +P  P +   +E     ++     T+  PAP+  + T P   +  AP   +   P
Sbjct: 651 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 710

Query: 255 FTLGKKPPFSDKPSIPA--------GRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP 306
            T    PP + + S P          +S  E  P++   P P   E   +   +P  K P
Sbjct: 711 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP 770

Query: 307 VPKHGWGPDRRENDEDDVHQRPL 329
                  P+     +D   +R L
Sbjct: 771 AATK---PEMTTTAKDKTTERDL 790


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 77/355 (21%), Positives = 118/355 (33%), Gaps = 29/355 (8%)

Query: 73  NKNEERRSIFTRKPQVPRF---PEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYE 129
           NK      I T KP  PR    P    S E           +  E+   ++    DG  +
Sbjct: 151 NKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK 210

Query: 130 SPNEEEEAPVEDDADYEPPPSND------EEALQNSILPAKPFPNSNSMYIDRPPSGKTP 183
           + + +E   +E  +  +  P++        +A   +  PA   P   +    + P+  TP
Sbjct: 211 TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP 270

Query: 184 QQPPVP-----PQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRS 238
           ++P        P  P    P        +P  P  T  +EP+ +    T K PAP+  + 
Sbjct: 271 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT----TPKEPAPTTTKE 326

Query: 239 TKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSS 298
             P   +S     +EP     K P    P  PA  +  E  P   K P P T E     +
Sbjct: 327 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE----PA 382

Query: 299 PLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSS 358
           P   K+P        P   +       + P P     P  + T     T P    P  + 
Sbjct: 383 PTTPKEP-------APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 435

Query: 359 HMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAE 413
             P    E   +  +SA   P      + + P     +      P KP P +P E
Sbjct: 436 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 490



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 66/294 (22%), Positives = 99/294 (33%), Gaps = 36/294 (12%)

Query: 146 EPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRN 205
           EP P+  + A      P +P P +      + P+  TP++P      P     P P    
Sbjct: 287 EPAPTTTKSA---PTTPKEPAPTTT-----KEPAPTTPKEPA-----PTTTKEPAPTTTK 333

Query: 206 HSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSD 265
            +P  P +     P +     T K PAP+  +   P   +  AP  +EP     K P   
Sbjct: 334 SAPTTPKEPAPTTPKKPAP-TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 392

Query: 266 KPSIPAGRSLGEHLPKIQKPPLPPTTERHE------------RSSPLPGKKPPVPKHGWG 313
            P  PA  +  E  P   K P P TT+               +S+P   K+P        
Sbjct: 393 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 452

Query: 314 PDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQ 373
           P   +       + P P     P  + T P +    +P  P P++    A + +    P 
Sbjct: 453 PTTPKEPSPTTTKEPAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 510

Query: 374 SASLPPYFSQGPSNRPPIRAEGRNFPLP------LPNKPRPPSPAEEENSLNEE 421
           +   P      P    P   +      P       P KP P +P E   +  EE
Sbjct: 511 TPKEPA--PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 562



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 78/354 (22%), Positives = 119/354 (33%), Gaps = 53/354 (14%)

Query: 130 SPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQP-PV 188
           +P   + AP       EP P+  +E       PA   P   +    + P+  TP++P P 
Sbjct: 445 APTTTKSAPTTPK---EPSPTTTKE-------PAPTTPKEPAPTTPKKPAPTTPKEPAPT 494

Query: 189 PPQRPMAAL---PPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDR 245
            P+ P       P P   +  +P  P +T    P +       KL AP+      P    
Sbjct: 495 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL-APTTPEKPAPTTPE 553

Query: 246 SLAPFD-REPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKK 304
            LAP    EP     + P    P   A  +  E  P   K P P T +  E +   P + 
Sbjct: 554 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--EPAPTTPKET 611

Query: 305 PPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSS-----------------NTFPSRST 347
            P    G  P   +       ++P P+  L P ++                  T P+   
Sbjct: 612 APTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 670

Query: 348 KPSPMNP------LPSSHMPGAFSESNSSFPQSAS---LPPYFSQGP----SNRPPIRAE 394
           +P+P  P       P    P    E   + P+  +   L P  ++GP    S++P     
Sbjct: 671 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 730

Query: 395 GRNFPL----PLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALRKINQDGT 444
               P     P P  P+ P+P   E        VS  T  +    + K   + T
Sbjct: 731 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 784



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 71/280 (25%), Positives = 96/280 (34%), Gaps = 52/280 (18%)

Query: 162 PAKPFPNSNSMYIDRPPSGKTPQQPPVP-PQRPMAALPPPPAGRNHSPLPPPQTNHEEPS 220
           P KP P +        P   TP  P  P P  P AA P       ++P  P  T  +EP+
Sbjct: 544 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-------NTPKEPAPTTPKEPA 596

Query: 221 RSRNHKTAKLPAPSIDRSTKPPLDRSLAPFD-REPF-TLGKKP------------PFS-- 264
            +    T K PAP+  + T P   +  AP   +EP  T  KKP            P S  
Sbjct: 597 PT----TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 652

Query: 265 -DKPSIPAGRSLGEHLPKIQKPPLP----PTTERHERSSPLPGKKPPVPKHGW------- 312
            DKP+    +      PK   P  P    PTT +    + L    P  PK          
Sbjct: 653 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 712

Query: 313 ---GPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNS 369
              GP    +D+        P P     ++ T P      +P  P P++      + S  
Sbjct: 713 TTKGPTSTTSDK--------PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 764

Query: 370 SFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPP 409
           S P +   P    + P    P        P  L N P+ P
Sbjct: 765 STPTTTKEPTTIHKSPDESTP-ELSAEPTPKALENSPKEP 803



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 43/203 (21%), Positives = 69/203 (33%), Gaps = 38/203 (18%)

Query: 162 PAKPFPNSNSMYIDRPPSGKTPQQP---------PVPPQRPMAALPPPPAG--------- 203
           P KP P   +    + P+  T  +P         P  P+ P    P  PA          
Sbjct: 632 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 691

Query: 204 --RNHSPLPPPQTNHEE----PSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDRE---P 254
             +  +P  P +   +E     ++     T+  PAP+  + T P   +  AP   +   P
Sbjct: 692 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 751

Query: 255 FTLGKKPPFSDKPSIPA--------GRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP 306
            T    PP + + S P          +S  E  P++   P P   E   +   +P  K P
Sbjct: 752 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP 811

Query: 307 VPKHGWGPDRRENDEDDVHQRPL 329
                  P+     +D   +R L
Sbjct: 812 AATK---PEMTTTAKDKTTERDL 831


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 77/355 (21%), Positives = 118/355 (33%), Gaps = 29/355 (8%)

Query: 73  NKNEERRSIFTRKPQVPRF---PEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYE 129
           NK      I T KP  PR    P    S E           +  E+   ++    DG  +
Sbjct: 203 NKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK 262

Query: 130 SPNEEEEAPVEDDADYEPPPSND------EEALQNSILPAKPFPNSNSMYIDRPPSGKTP 183
           + + +E   +E  +  +  P++        +A   +  PA   P   +    + P+  TP
Sbjct: 263 TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP 322

Query: 184 QQPPVP-----PQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRS 238
           ++P        P  P    P        +P  P  T  +EP+ +    T K PAP+  + 
Sbjct: 323 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT----TPKEPAPTTTKE 378

Query: 239 TKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSS 298
             P   +S     +EP     K P    P  PA  +  E  P   K P P T E     +
Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE----PA 434

Query: 299 PLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSS 358
           P   K+P        P   +       + P P     P  + T     T P    P  + 
Sbjct: 435 PTTPKEP-------APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 487

Query: 359 HMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAE 413
             P    E   +  +SA   P      + + P     +      P KP P +P E
Sbjct: 488 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 542



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 66/294 (22%), Positives = 99/294 (33%), Gaps = 36/294 (12%)

Query: 146 EPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRN 205
           EP P+  + A      P +P P +      + P+  TP++P      P     P P    
Sbjct: 339 EPAPTTTKSA---PTTPKEPAPTTT-----KEPAPTTPKEPA-----PTTTKEPAPTTTK 385

Query: 206 HSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSD 265
            +P  P +     P +     T K PAP+  +   P   +  AP  +EP     K P   
Sbjct: 386 SAPTTPKEPAPTTPKKPAP-TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 444

Query: 266 KPSIPAGRSLGEHLPKIQKPPLPPTTERHE------------RSSPLPGKKPPVPKHGWG 313
            P  PA  +  E  P   K P P TT+               +S+P   K+P        
Sbjct: 445 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 504

Query: 314 PDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQ 373
           P   +       + P P     P  + T P +    +P  P P++    A + +    P 
Sbjct: 505 PTTPKEPSPTTTKEPAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 562

Query: 374 SASLPPYFSQGPSNRPPIRAEGRNFPLP------LPNKPRPPSPAEEENSLNEE 421
           +   P      P    P   +      P       P KP P +P E   +  EE
Sbjct: 563 TPKEPA--PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 614



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 78/354 (22%), Positives = 119/354 (33%), Gaps = 53/354 (14%)

Query: 130 SPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQP-PV 188
           +P   + AP       EP P+  +E       PA   P   +    + P+  TP++P P 
Sbjct: 497 APTTTKSAPTTPK---EPSPTTTKE-------PAPTTPKEPAPTTPKKPAPTTPKEPAPT 546

Query: 189 PPQRPMAAL---PPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDR 245
            P+ P       P P   +  +P  P +T    P +       KL AP+      P    
Sbjct: 547 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL-APTTPEKPAPTTPE 605

Query: 246 SLAPFD-REPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKK 304
            LAP    EP     + P    P   A  +  E  P   K P P T +  E +   P + 
Sbjct: 606 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--EPAPTTPKET 663

Query: 305 PPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSS-----------------NTFPSRST 347
            P    G  P   +       ++P P+  L P ++                  T P+   
Sbjct: 664 APTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 722

Query: 348 KPSPMNP------LPSSHMPGAFSESNSSFPQSAS---LPPYFSQGP----SNRPPIRAE 394
           +P+P  P       P    P    E   + P+  +   L P  ++GP    S++P     
Sbjct: 723 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 782

Query: 395 GRNFPL----PLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALRKINQDGT 444
               P     P P  P+ P+P   E        VS  T  +    + K   + T
Sbjct: 783 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 836



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 71/280 (25%), Positives = 96/280 (34%), Gaps = 52/280 (18%)

Query: 162 PAKPFPNSNSMYIDRPPSGKTPQQPPVP-PQRPMAALPPPPAGRNHSPLPPPQTNHEEPS 220
           P KP P +        P   TP  P  P P  P AA P       ++P  P  T  +EP+
Sbjct: 596 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-------NTPKEPAPTTPKEPA 648

Query: 221 RSRNHKTAKLPAPSIDRSTKPPLDRSLAPFD-REPF-TLGKKP------------PFS-- 264
            +    T K PAP+  + T P   +  AP   +EP  T  KKP            P S  
Sbjct: 649 PT----TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 704

Query: 265 -DKPSIPAGRSLGEHLPKIQKPPLP----PTTERHERSSPLPGKKPPVPKHGW------- 312
            DKP+    +      PK   P  P    PTT +    + L    P  PK          
Sbjct: 705 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 764

Query: 313 ---GPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNS 369
              GP    +D+        P P     ++ T P      +P  P P++      + S  
Sbjct: 765 TTKGPTSTTSDK--------PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 816

Query: 370 SFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPP 409
           S P +   P    + P    P        P  L N P+ P
Sbjct: 817 STPTTTKEPTTIHKSPDESTP-ELSAEPTPKALENSPKEP 855



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 43/203 (21%), Positives = 69/203 (33%), Gaps = 38/203 (18%)

Query: 162 PAKPFPNSNSMYIDRPPSGKTPQQP---------PVPPQRPMAALPPPPAG--------- 203
           P KP P   +    + P+  T  +P         P  P+ P    P  PA          
Sbjct: 684 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 743

Query: 204 --RNHSPLPPPQTNHEE----PSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDRE---P 254
             +  +P  P +   +E     ++     T+  PAP+  + T P   +  AP   +   P
Sbjct: 744 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 803

Query: 255 FTLGKKPPFSDKPSIPA--------GRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP 306
            T    PP + + S P          +S  E  P++   P P   E   +   +P  K P
Sbjct: 804 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP 863

Query: 307 VPKHGWGPDRRENDEDDVHQRPL 329
                  P+     +D   +R L
Sbjct: 864 AATK---PEMTTTAKDKTTERDL 883


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 77/355 (21%), Positives = 118/355 (33%), Gaps = 29/355 (8%)

Query: 73  NKNEERRSIFTRKPQVPRF---PEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYE 129
           NK      I T KP  PR    P    S E           +  E+   ++    DG  +
Sbjct: 244 NKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK 303

Query: 130 SPNEEEEAPVEDDADYEPPPSND------EEALQNSILPAKPFPNSNSMYIDRPPSGKTP 183
           + + +E   +E  +  +  P++        +A   +  PA   P   +    + P+  TP
Sbjct: 304 TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP 363

Query: 184 QQPPVP-----PQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRS 238
           ++P        P  P    P        +P  P  T  +EP+ +    T K PAP+  + 
Sbjct: 364 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT----TPKEPAPTTTKE 419

Query: 239 TKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSS 298
             P   +S     +EP     K P    P  PA  +  E  P   K P P T E     +
Sbjct: 420 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE----PA 475

Query: 299 PLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSS 358
           P   K+P        P   +       + P P     P  + T     T P    P  + 
Sbjct: 476 PTTPKEP-------APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 528

Query: 359 HMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAE 413
             P    E   +  +SA   P      + + P     +      P KP P +P E
Sbjct: 529 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 583



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 66/294 (22%), Positives = 99/294 (33%), Gaps = 36/294 (12%)

Query: 146 EPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRN 205
           EP P+  + A      P +P P +      + P+  TP++P      P     P P    
Sbjct: 380 EPAPTTTKSA---PTTPKEPAPTTT-----KEPAPTTPKEPA-----PTTTKEPAPTTTK 426

Query: 206 HSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSD 265
            +P  P +     P +     T K PAP+  +   P   +  AP  +EP     K P   
Sbjct: 427 SAPTTPKEPAPTTPKKPAP-TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 485

Query: 266 KPSIPAGRSLGEHLPKIQKPPLPPTTERHE------------RSSPLPGKKPPVPKHGWG 313
            P  PA  +  E  P   K P P TT+               +S+P   K+P        
Sbjct: 486 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 545

Query: 314 PDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQ 373
           P   +       + P P     P  + T P +    +P  P P++    A + +    P 
Sbjct: 546 PTTPKEPSPTTTKEPAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 603

Query: 374 SASLPPYFSQGPSNRPPIRAEGRNFPLP------LPNKPRPPSPAEEENSLNEE 421
           +   P      P    P   +      P       P KP P +P E   +  EE
Sbjct: 604 TPKEPA--PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 655



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 78/354 (22%), Positives = 119/354 (33%), Gaps = 53/354 (14%)

Query: 130 SPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQP-PV 188
           +P   + AP       EP P+  +E       PA   P   +    + P+  TP++P P 
Sbjct: 538 APTTTKSAPTTPK---EPSPTTTKE-------PAPTTPKEPAPTTPKKPAPTTPKEPAPT 587

Query: 189 PPQRPMAAL---PPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDR 245
            P+ P       P P   +  +P  P +T    P +       KL AP+      P    
Sbjct: 588 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL-APTTPEKPAPTTPE 646

Query: 246 SLAPFD-REPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKK 304
            LAP    EP     + P    P   A  +  E  P   K P P T +  E +   P + 
Sbjct: 647 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--EPAPTTPKET 704

Query: 305 PPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSS-----------------NTFPSRST 347
            P    G  P   +       ++P P+  L P ++                  T P+   
Sbjct: 705 APTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 763

Query: 348 KPSPMNP------LPSSHMPGAFSESNSSFPQSAS---LPPYFSQGP----SNRPPIRAE 394
           +P+P  P       P    P    E   + P+  +   L P  ++GP    S++P     
Sbjct: 764 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 823

Query: 395 GRNFPL----PLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALRKINQDGT 444
               P     P P  P+ P+P   E        VS  T  +    + K   + T
Sbjct: 824 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 877



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 71/280 (25%), Positives = 96/280 (34%), Gaps = 52/280 (18%)

Query: 162 PAKPFPNSNSMYIDRPPSGKTPQQPPVP-PQRPMAALPPPPAGRNHSPLPPPQTNHEEPS 220
           P KP P +        P   TP  P  P P  P AA P       ++P  P  T  +EP+
Sbjct: 637 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-------NTPKEPAPTTPKEPA 689

Query: 221 RSRNHKTAKLPAPSIDRSTKPPLDRSLAPFD-REPF-TLGKKP------------PFS-- 264
            +    T K PAP+  + T P   +  AP   +EP  T  KKP            P S  
Sbjct: 690 PT----TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 745

Query: 265 -DKPSIPAGRSLGEHLPKIQKPPLP----PTTERHERSSPLPGKKPPVPKHGW------- 312
            DKP+    +      PK   P  P    PTT +    + L    P  PK          
Sbjct: 746 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 805

Query: 313 ---GPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNS 369
              GP    +D+        P P     ++ T P      +P  P P++      + S  
Sbjct: 806 TTKGPTSTTSDK--------PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 857

Query: 370 SFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPP 409
           S P +   P    + P    P        P  L N P+ P
Sbjct: 858 STPTTTKEPTTIHKSPDESTP-ELSAEPTPKALENSPKEP 896



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 43/203 (21%), Positives = 69/203 (33%), Gaps = 38/203 (18%)

Query: 162 PAKPFPNSNSMYIDRPPSGKTPQQP---------PVPPQRPMAALPPPPAG--------- 203
           P KP P   +    + P+  T  +P         P  P+ P    P  PA          
Sbjct: 725 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 784

Query: 204 --RNHSPLPPPQTNHEE----PSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDRE---P 254
             +  +P  P +   +E     ++     T+  PAP+  + T P   +  AP   +   P
Sbjct: 785 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 844

Query: 255 FTLGKKPPFSDKPSIPA--------GRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP 306
            T    PP + + S P          +S  E  P++   P P   E   +   +P  K P
Sbjct: 845 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP 904

Query: 307 VPKHGWGPDRRENDEDDVHQRPL 329
                  P+     +D   +R L
Sbjct: 905 AATK---PEMTTTAKDKTTERDL 924


>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
          Length = 1170

 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 82/317 (25%), Positives = 120/317 (37%), Gaps = 66/317 (20%)

Query: 136 EAPVEDDADYEPPPSNDEEALQN--------SILPAK-PFPNSNSMYIDRPPSGKTPQQ- 185
           + PV   A   PPP   ++ +++         +LP + P   S    +  PP  +TP+  
Sbjct: 312 QPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMM 371

Query: 186 ---PPVPPQR-----------------------PMAALPPPPAGRNHSPLPPPQTNHEEP 219
              PPV PQ+                       P+ + P P  G    P PP    H  P
Sbjct: 372 MTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQH-TP 430

Query: 220 SRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHL 279
               N  +     P  D+   PP      P DR+PF LG     S +P  P+   L +  
Sbjct: 431 GPVPNSFSQPPRLPLQDQWRAPP-----PPQDRDPFFLG----VSGEPRFPSHLFLEQRS 481

Query: 280 PKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLP-QPALLPMS 338
           P    PP PP       S P+P  + P+P    GP   +  +  V  R  P +PAL P  
Sbjct: 482 P----PPPPPPPTLLNSSHPVP-TQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQP-- 534

Query: 339 SNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLP-PYFSQGPSNRPPIRAEGRN 397
                     P P+  L  S  PG+ +      P+   LP P     P++  P      +
Sbjct: 535 ----------PGPVGILHFS-QPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLH 583

Query: 398 FPLPLPNKPRPPSPAEE 414
            PLP P++P+P  P ++
Sbjct: 584 PPLPPPHQPQPQQPQQQ 600



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 64/259 (24%), Positives = 89/259 (34%), Gaps = 32/259 (12%)

Query: 147 PPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSG--KTPQQPPVPPQRPM--AALPPPPA 202
           PPP      L NS   + P P  + +   +P     +  QQP  P +RP+  A  PP P 
Sbjct: 482 PPPPPPPPTLLNS---SHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPV 538

Query: 203 GRNHSPLPPPQTNHEE-PSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKP 261
           G  H   P   T     P R        LP P      +P L     P  + P      P
Sbjct: 539 GILHFSQPGSATTRPFIPPRQ-----PFLPGPG-----QPFLPTHTQPNLQGPLHPPLPP 588

Query: 262 PFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDE 321
           P   +P  P  +   +H P  Q P  PP   +H+     P + PP  +H           
Sbjct: 589 PHQPQPQQPQQQPPPQHQPPHQPPHQPP--PQHQPPPQHPPQHPPQHQH----------H 636

Query: 322 DDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYF 381
              H   +P P L+PMS   F        P         P      +++  Q+ S  P  
Sbjct: 637 HHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQ 696

Query: 382 SQGPSNRPPIRAEGRNFPL 400
              P+   P  +  R  P+
Sbjct: 697 QMQPT--APRNSNLRELPI 713



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 70/246 (28%), Positives = 91/246 (36%), Gaps = 52/246 (21%)

Query: 183 PQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSID--RSTK 240
           P QPPV PQ P    PPPP        PPPQ   ++P RS        P   +       
Sbjct: 310 PTQPPVVPQAP----PPPP--------PPPQ---QQPIRSLFQPQPLQPLLPVQHPHHPS 354

Query: 241 PPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEH-----LPKIQKPPLPPTTERHE 295
           PP    + P    P  +   PP +  P  P    +  H     +  +Q P LP  ++   
Sbjct: 355 PPQGMHMPPQLETPRMMMTPPPVT--PQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRP 412

Query: 296 RSSP--LPGKKPPVPKHGWGP-------DRRENDEDDVHQRPLPQ---PALLPMSSN-TF 342
              P   PG  P  P+H  GP         R   +D     P PQ   P  L +S    F
Sbjct: 413 AVGPQRFPG-PPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRF 471

Query: 343 PS------RSTKPSPMNP--LPSSH-----MPGAFSESNSSFPQSASLPPYFSQGPSNRP 389
           PS      RS  P P  P  L SSH      P  F++   +F Q    P +  + P  RP
Sbjct: 472 PSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPV-RP 530

Query: 390 PIRAEG 395
            ++  G
Sbjct: 531 ALQPPG 536



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 50/227 (22%), Positives = 78/227 (34%), Gaps = 45/227 (19%)

Query: 149 PSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALP--PPPAGRNH 206
           P++ +  LQ  + P  P P+         P  + PQQ P P  +P    P  PPP    H
Sbjct: 571 PTHTQPNLQGPLHPPLPPPHQ--------PQPQQPQQQPPPQHQPPHQPPHQPPP---QH 619

Query: 207 SPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDK 266
            P PP       P    +H    L  P       PPL     P  R      +    S +
Sbjct: 620 QP-PPQHPPQHPPQHQHHHHHHHLSVP------PPPLMPMSQPQFRPHVQTAQPQASSSR 672

Query: 267 PSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQ 326
              P  + L  +           TT ++    P+   +P  P++            ++ +
Sbjct: 673 MQCPQRQGLRHN-----------TTSQNVSKRPMQQMQPTAPRN-----------SNLRE 710

Query: 327 RPLPQPALLPMSS---NTFPSRSTKPSPMNPLPSSHMPGAFSESNSS 370
            P+    ++ MSS   +  PS   KP      PS  + G+ S    +
Sbjct: 711 LPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKT 757


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 70/257 (27%), Positives = 94/257 (36%), Gaps = 46/257 (17%)

Query: 140  EDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKT--PQQPPVPPQRPMAAL 197
            E D     P + + EA      P   + N       RP S +   P+ PP PP     A 
Sbjct: 1144 ESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPP----AE 1199

Query: 198  PPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTL 257
            PPP    +  PLPPP+    +P        AK P      S KP L + +      P   
Sbjct: 1200 PPPTDLAHLPPLPPPEGEARKP--------AKPPV-----SPKPVLTQPVPKLQGSPTPT 1246

Query: 258  GKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKK-PPVPKHGWGPDR 316
             KK P     S    R+ G   P   KPP PPT       +P P K    +P    GP  
Sbjct: 1247 SKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPT-------APKPVKAVAGLPSGSAGPS- 1298

Query: 317  RENDEDDVHQRPLPQPALLPMSS-----NTFPSRSTKPS--PMNPLPSSHMPGAFSESNS 369
                       P P PA  P ++      T PS    P+  P    P+ H+P     + +
Sbjct: 1299 -----------PAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAA 1347

Query: 370  SFPQSASLPPYFSQGPS 386
            +   +A+ PP   +G S
Sbjct: 1348 AAAAAAAAPPAPPEGAS 1364



 Score = 30.0 bits (66), Expect = 5.5
 Identities = 41/179 (22%), Positives = 61/179 (34%), Gaps = 39/179 (21%)

Query: 148 PPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKT------PQQPPVPPQRPMAALPPPP 201
           PP+  E  +    LP  P     +  + +P  G+       P  PPVP   P   LPP  
Sbjct: 812 PPT--ERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEA 869

Query: 202 AGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPF-TLGKK 260
                 P            + R H   +  A      ++P  D  L P    P+ T+ ++
Sbjct: 870 DAEPGRP------------KKRAHSLNRYAA----SDSEPERDELLVPAAAGPYATVQRR 913

Query: 261 PPFSDKPSIPAG------RSLGEHLPKIQKPPLPPTTERHERS--------SPLPGKKP 305
              S     PAG      RS    +   +K P PP  +R   +         P+P  +P
Sbjct: 914 VGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPPPPPKRSSSALASANLADEPVPDAEP 972


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 79/274 (28%), Positives = 90/274 (32%), Gaps = 37/274 (13%)

Query: 147  PPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPP--AGR 204
            PPP      +    LP+   P         PP   T   PP PP  P A +PPPP   G 
Sbjct: 877  PPPPPPLPGMTVPTLPSTAIPQP-------PPLQGTEMLPPPPPPLPGAGIPPPPPLPGA 929

Query: 205  NHSPLPP-PQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPF 263
               PLPP P      P           P P       PPL  +  P        G  PP 
Sbjct: 930  GILPLPPLPGAGIPPPP----------PLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPP- 978

Query: 264  SDKPSIP-AGRSLGEHLPKIQKPPLPPTTERH-ERSSPLPG----KKPPVPKHGWGPDRR 317
               P +P AG      LP    PP PP          PLPG      PP+P  G  P   
Sbjct: 979  ---PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1035

Query: 318  ENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASL 377
                      PLP   + P      P     P P  PLP + +P       +  P     
Sbjct: 1036 LPGAGIPPPPPLPGAGIPP--PPPLPGAGIPPPP--PLPGAGIPPPPPLPGAGIPPP--- 1088

Query: 378  PPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSP 411
            PP    G    PP+   G   P PLP    PP P
Sbjct: 1089 PPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPP 1122



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 78/272 (28%), Positives = 89/272 (32%), Gaps = 42/272 (15%)

Query: 147  PPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNH 206
            PPP     A    I P  P P +    I  PP       PP PP       PPPP     
Sbjct: 987  PPPPPLPGA---GIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1040

Query: 207  SPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDK 266
             P PPP      P           P P       PPL  +  P        G  PP    
Sbjct: 1041 IPPPPPLPGAGIPPPP--------PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP---- 1088

Query: 267  PSIP-AGRSLGEHLPKIQKPPLPPTTERH-ERSSPLPGK----KPPVPKHGWGPDRREND 320
            P +P AG      LP +  PP PP          PLPG      PP+P  G  P      
Sbjct: 1089 PPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---- 1144

Query: 321  EDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPY 380
                   PLP+  + P      P     P P  PLP + +P          P    LP  
Sbjct: 1145 -------PLPRVGIPPPPP--LPGAGIPPPP--PLPGAGIPPPPPLPGVGIPPPPPLPGV 1193

Query: 381  FSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPA 412
                P   PP+   G   P PLP    PP+PA
Sbjct: 1194 GIPPP---PPLPGAGIPPPPPLPGMGIPPAPA 1222



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 66/246 (26%), Positives = 87/246 (35%), Gaps = 36/246 (14%)

Query: 167  PNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRN-HSPLPPPQTNHEEPSRSRNH 225
            P   S+ +D     ++  QPP PP    +A    P  +  HS     QT+HE    S   
Sbjct: 791  PRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFK 850

Query: 226  KTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKP 285
             +  +P+P       PPL  + +        LG  PP    P  P        LP    P
Sbjct: 851  NSCNIPSP-------PPLPCTESSSSMP--GLGMVPP----PPPPLPGMTVPTLPSTAIP 897

Query: 286  PLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSR 345
              PP     + +  LP   PP+P  G  P             PLP   +LP+     P  
Sbjct: 898  QPPPL----QGTEMLPPPPPPLPGAGIPP-----------PPPLPGAGILPLP--PLPGA 940

Query: 346  STKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNK 405
               P P  PLP + +P       +  P     PP    G    PP+   G   P PLP  
Sbjct: 941  GIPPPP--PLPGAAIPPPPPLPGAGIPLP---PPLPGAGIPPPPPLPGAGIPPPPPLPGA 995

Query: 406  PRPPSP 411
              PP P
Sbjct: 996  GIPPPP 1001



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 69/243 (28%), Positives = 76/243 (31%), Gaps = 41/243 (16%)

Query: 147  PPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNH 206
            PPP     A    I P  P P +    I  PP       PP PP   +   PPPP     
Sbjct: 1064 PPPPPLPGA---GIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAG 1117

Query: 207  SPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDK 266
             P PPP      P           P P       PPL R   P        G  PP    
Sbjct: 1118 IPPPPPLPGAGIPPPP--------PLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPP---- 1165

Query: 267  PSIP-AGRSLGEHLPKIQKPPLPPTT-ERHERSSPLPGK--KPPVPKHGWGPDRRENDED 322
            P +P AG      LP +  PP PP          PLPG    PP P  G G         
Sbjct: 1166 PPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIP------- 1218

Query: 323  DVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSAS-LPPYF 381
                 P P P L P      P     P P+ P+    +      S    PQ    LPP  
Sbjct: 1219 -----PAPAPPLPP------PGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPL 1267

Query: 382  SQG 384
              G
Sbjct: 1268 PSG 1270



 Score = 30.4 bits (67), Expect = 4.2
 Identities = 42/164 (25%), Positives = 55/164 (33%), Gaps = 28/164 (17%)

Query: 91  FPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPS 150
           FPE     E          + D E    ++D  +D    SP EE    V +DA       
Sbjct: 325 FPEAGPGEEAAGAPVRGAGDTDEEG---EEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEE 381

Query: 151 NDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQR---PMAALPPPPAGRNHS 207
            +EEA       A   P S                 P P QR   P   + P        
Sbjct: 382 PEEEAQGPDAPAAASLPGS-----------------PAPSQRCFKPYPLITPCYIKTTTR 424

Query: 208 PLPPPQTNHEEPSRSRNH--KTAKLPAPSIDRSTKPPLDRSLAP 249
            L  P  NH  PS+S N   +  + P PS+ R ++  L    AP
Sbjct: 425 QLSSP--NH-SPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAP 465



 Score = 29.6 bits (65), Expect = 7.2
 Identities = 34/134 (25%), Positives = 45/134 (33%), Gaps = 26/134 (19%)

Query: 181 KTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTK 240
           + PQQPP P   P++  P  PA +  +   P  T    P      + A  P         
Sbjct: 288 REPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPV-------- 339

Query: 241 PPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGR----SLGEHLPKIQKPPLPPTTERHER 296
               R     D E    G++  F D P    G      +GE  P  Q+    P  E    
Sbjct: 340 ----RGAGDTDEE----GEEDAFEDAPRGSPGEEWAPEVGEDAP--QRLGEEPEEEAQGP 389

Query: 297 SSP----LPGKKPP 306
            +P    LPG   P
Sbjct: 390 DAPAAASLPGSPAP 403


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 73/279 (26%), Positives = 95/279 (34%), Gaps = 56/279 (20%)

Query: 148 PPSNDEEALQNSILPAKP--FPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRN 205
           PPS    +L +  L A     P+     +  PP    PQ PP     P+ A P PPA   
Sbjct: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPP----PQAPPALALPPLQAPPSPPASPP 416

Query: 206 HSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSD 265
            SPL  P             +    P PS      PP+    +P    P +    PP   
Sbjct: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPS------PPVQAPFSPPASPPVSPSATPPSQA 470

Query: 266 KPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVH 325
            PS+ A        P +Q PP PP +     S+  P + PP                   
Sbjct: 471 PPSLAA--------PPLQVPPSPPASPPMSPSATPPPQAPP------------------- 503

Query: 326 QRPLPQP--ALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLP--PYF 381
             PL  P   L        P+ +T P    P P +  PG      + F  SASLP  P  
Sbjct: 504 --PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG-----QAPFSPSASLPMSPLA 556

Query: 382 SQGPSNRPPIRAEGRNFPLPLPNKP------RPPSPAEE 414
           +  P   P + A     P   P  P      RPP+P  +
Sbjct: 557 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 595



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 70/307 (22%), Positives = 104/307 (33%), Gaps = 58/307 (18%)

Query: 147 PPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALP-------- 198
           PP       L     P+   PN+ ++++ + P    P  P   P  P A+ P        
Sbjct: 408 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 467

Query: 199 ----------------PPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPP 242
                            PPA    SP   P      P  +   + AK P  +      PP
Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 527

Query: 243 LDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGE--------HLPKIQKPPLPPTTERH 294
           L    +P    P +   + PFS   S+P                 P +Q PP PP +   
Sbjct: 528 LQALPSP----PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 583

Query: 295 ERSSPLPGKKPPVPKHGWGPDRRENDED---DVHQRPLPQPALLPMSSNTFP-------S 344
           +       ++PP P    GPD   +       +   P P P+  P S+ + P       S
Sbjct: 584 QAP-----RRPPTP----GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 634

Query: 345 RSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGR-NFPLPLP 403
            ++ P  +    S    GA +        +A  P  +S+GP+  PP+   G    PLP P
Sbjct: 635 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA--PPLAFRGAPGAPLPWP 692

Query: 404 NKPRPPS 410
               P S
Sbjct: 693 PATGPGS 699



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 45/185 (24%), Positives = 65/185 (35%), Gaps = 34/185 (18%)

Query: 148 PPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVP--------PQRPMAALPP 199
           PP      L   +L   P P ++       P+ + P++PP P        P+  +A  P 
Sbjct: 558 PPPQAPPVLAAPLLQVPPSPPAS-------PTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610

Query: 200 PPAGRNHSPLP----PPQTNHEEPSRSRNHKTAKLPA-PSIDRSTKPPLDRSLAPFDREP 254
           PP   + SP      P    H   + S   +     + P    +  PP D  LA      
Sbjct: 611 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 670

Query: 255 FTLGKKPP--FSDKPSIP------AGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP 306
           ++ G  PP  F   P  P       G    + L  I +      TE  E ++P PG   P
Sbjct: 671 WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE------TEGPESATPAPGALDP 724

Query: 307 VPKHG 311
            P  G
Sbjct: 725 GPSPG 729


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 73/279 (26%), Positives = 95/279 (34%), Gaps = 56/279 (20%)

Query: 148 PPSNDEEALQNSILPAKP--FPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRN 205
           PPS    +L +  L A     P+     +  PP    PQ PP     P+ A P PPA   
Sbjct: 322 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPP----PQAPPALALPPLQAPPSPPASPP 377

Query: 206 HSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSD 265
            SPL  P             +    P PS      PP+    +P    P +    PP   
Sbjct: 378 LSPLATPSPQAPNALAVHLLQAPFSPPPS------PPVQAPFSPPASPPVSPSATPPSQA 431

Query: 266 KPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVH 325
            PS+ A        P +Q PP PP +     S+  P + PP                   
Sbjct: 432 PPSLAA--------PPLQVPPSPPASPPMSPSATPPPQAPP------------------- 464

Query: 326 QRPLPQP--ALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLP--PYF 381
             PL  P   L        P+ +T P    P P +  PG      + F  SASLP  P  
Sbjct: 465 --PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG-----QAPFSPSASLPMSPLA 517

Query: 382 SQGPSNRPPIRAEGRNFPLPLPNKP------RPPSPAEE 414
           +  P   P + A     P   P  P      RPP+P  +
Sbjct: 518 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 556



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 70/307 (22%), Positives = 104/307 (33%), Gaps = 58/307 (18%)

Query: 147 PPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALP-------- 198
           PP       L     P+   PN+ ++++ + P    P  P   P  P A+ P        
Sbjct: 369 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 428

Query: 199 ----------------PPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPP 242
                            PPA    SP   P      P  +   + AK P  +      PP
Sbjct: 429 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 488

Query: 243 LDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGE--------HLPKIQKPPLPPTTERH 294
           L    +P    P +   + PFS   S+P                 P +Q PP PP +   
Sbjct: 489 LQALPSP----PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 544

Query: 295 ERSSPLPGKKPPVPKHGWGPDRRENDED---DVHQRPLPQPALLPMSSNTFP-------S 344
           +       ++PP P    GPD   +       +   P P P+  P S+ + P       S
Sbjct: 545 QAP-----RRPPTP----GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 595

Query: 345 RSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGR-NFPLPLP 403
            ++ P  +    S    GA +        +A  P  +S+GP+  PP+   G    PLP P
Sbjct: 596 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA--PPLAFRGAPGAPLPWP 653

Query: 404 NKPRPPS 410
               P S
Sbjct: 654 PATGPGS 660



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 45/185 (24%), Positives = 65/185 (35%), Gaps = 34/185 (18%)

Query: 148 PPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVP--------PQRPMAALPP 199
           PP      L   +L   P P ++       P+ + P++PP P        P+  +A  P 
Sbjct: 519 PPPQAPPVLAAPLLQVPPSPPAS-------PTLQAPRRPPTPGPDTSVSGPRLTLALAPG 571

Query: 200 PPAGRNHSPLP----PPQTNHEEPSRSRNHKTAKLPA-PSIDRSTKPPLDRSLAPFDREP 254
           PP   + SP      P    H   + S   +     + P    +  PP D  LA      
Sbjct: 572 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 631

Query: 255 FTLGKKPP--FSDKPSIP------AGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP 306
           ++ G  PP  F   P  P       G    + L  I +      TE  E ++P PG   P
Sbjct: 632 WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE------TEGPESATPAPGALDP 685

Query: 307 VPKHG 311
            P  G
Sbjct: 686 GPSPG 690



 Score = 37.4 bits (85), Expect = 0.035
 Identities = 62/263 (23%), Positives = 79/263 (30%), Gaps = 47/263 (17%)

Query: 167 PNSNSMYIDRPP-SGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTN-----HEEPS 220
           P +      RPP SG+  + PP     P     P  A     P P  Q        E  +
Sbjct: 75  PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 134

Query: 221 RSRNHKTAKLPAPSID--RSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEH 278
           R +  +  K  A S    R T  P             T G   P   + S  AG  +G  
Sbjct: 135 RGKATEAPKRSALSAGARRDTSGP-------------TPGTPSPAMARRSRAAGTEVGLP 181

Query: 279 LPKIQKPPLPPT---------TERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPL 329
            P     P PPT            H  + P P  +   P  G G  R  +        PL
Sbjct: 182 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR-PSAGGGLQRPASRSLSSSATPL 240

Query: 330 PQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRP 389
             PA    S+   P     PS   P P                  A  PP  +    +  
Sbjct: 241 SSPARSGPSARGTPRAPAHPS--QPKPKG--------------LQALRPPQVTPPRKDAA 284

Query: 390 PIRAEGRNFPLPLPNKPRPPSPA 412
           P      + PL  P+   PPSP+
Sbjct: 285 PALGPLSSSPLATPSPSAPPSPS 307


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 71/292 (24%), Positives = 104/292 (35%), Gaps = 76/292 (26%)

Query: 162 PAKPFPNSNSM--YIDRPPSGKTPQQPPVPP------------------QRPMAALPPPP 201
           P  P   S S+   I  PP+G  P  PP PP                    P  + PPPP
Sbjct: 687 PTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPP 746

Query: 202 AGRNH----------SPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFD 251
              +           +P PPP      P ++       +PAP+  ++  P + ++  P  
Sbjct: 747 LKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTP 806

Query: 252 REPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHG 311
             P      PP   +P+ PA             PP PPT        P+P   P +PK  
Sbjct: 807 TPPV-----PPAKKQPAFPASYI----------PPSPPTP-------PVPVPPPTLPK-- 842

Query: 312 WGPDRRENDEDDVHQRPL-PQPALLPMSSNTFPSRSTKPS----PMNPLPSS---HMPGA 363
                +++        PL P P+++   ++ FP   T P+    P+ P+P++     P A
Sbjct: 843 -----QQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPA 897

Query: 364 FSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFP----LPLPNKPRPPSP 411
                   P S  +P      P   PP       FP     P+P  P PP P
Sbjct: 898 VKAKPKWQPSSIPVP-----SPDFPPPPPESSLVFPPPPPSPVPAPPPPPPP 944



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 61/252 (24%), Positives = 92/252 (36%), Gaps = 28/252 (11%)

Query: 176 RPPSGKTPQQPPVPPQ---RPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPA 232
           +PP+    Q   V PQ    P   +PPPP      P PPP T    P  +         A
Sbjct: 685 KPPTPPVMQSQSVKPQILVPPNGVVPPPP------PPPPPPT----PGSAMAQLKPAPCA 734

Query: 233 PSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTE 292
           PS+ + + PP    +             PP    P IPA   L    P      +P  T 
Sbjct: 735 PSLPQFSAPPPPLKIHQVQHITQVAPPTPP--PPPPIPA--PLPPQAPPKPLVTIPAPTS 790

Query: 293 RHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPM 352
               +  +    PP P     P +++      +  P P    +P+   T P + +  +  
Sbjct: 791 TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKP 850

Query: 353 NPLPSSHMPGAFSESNSSFPQSASLPPYFSQ---------GPSNRPPIRAEGRNFP--LP 401
            P P S +P    +  S FP   + P   SQ          P + P ++A+ +  P  +P
Sbjct: 851 PPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIP 910

Query: 402 LPNKPRPPSPAE 413
           +P+   PP P E
Sbjct: 911 VPSPDFPPPPPE 922



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 69/276 (25%), Positives = 105/276 (38%), Gaps = 57/276 (20%)

Query: 147 PPPSNDEEALQNSILPAKPFPNSNSM--YIDRPPSGKTPQQPPVPPQRPMAALPPPPAGR 204
           PPP        +++   KP P + S+  +   PP  K  Q   +    P    PPPP   
Sbjct: 712 PPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPI-- 769

Query: 205 NHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFS 264
             +PLPP     + P +        +PAP+  ++  P + ++  P    P      PP  
Sbjct: 770 -PAPLPP-----QAPPK----PLVTIPAPTSTKTVAPVVTQAAPPTPTPPV-----PPAK 814

Query: 265 DKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDV 324
            +P+ PA             PP PPT        P+P   P +PK       +++     
Sbjct: 815 KQPAFPAS----------YIPPSPPT-------PPVPVPPPTLPK-------QQSFCAKP 850

Query: 325 HQRPL-PQPALLPMSSNTFPSRSTKPS----PMNPLPSS---HMPGAFSESNSSFPQSAS 376
              PL P P+++   ++ FP   T P+    P+ P+P++     P A        P S  
Sbjct: 851 PPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIP 910

Query: 377 LPPYFSQGPSNRPPIRAEGRNFPLPLPNK-PRPPSP 411
           +P      P   PP       FP P P+  P PP P
Sbjct: 911 VP-----SPDFPPPPPESSLVFPPPPPSPVPAPPPP 941



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 76/300 (25%), Positives = 106/300 (35%), Gaps = 85/300 (28%)

Query: 130  SPNEEEEAPVEDDADYEPPPSNDE--EALQNSILPAKPFPNSNSMYIDRP---PSG---K 181
            SP     + V+  A   PPP      E+     +PA   P S      +P   PS     
Sbjct: 853  SPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVP 912

Query: 182  TPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKP 241
            +P  PP PP+  +   PPPP+     P PPP T                 +P+ D+S  P
Sbjct: 913  SPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPT----------------ASPTPDKSGSP 956

Query: 242  PLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLP 301
                            GKK   + K S P G+          KP  PPT +R+       
Sbjct: 957  ----------------GKK---TSKTSSPGGK----------KP--PPTPQRNSSIKSSS 985

Query: 302  GKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMP 361
            G + P PK       R + +  V +         P + +  PS+ T P P  P      P
Sbjct: 986  GAEHPEPK-------RPSVDSLVSK-------FTPPAESGSPSKETLPPPAAP----PKP 1027

Query: 362  GAFSESNSSFPQSASLPPYFSQG--PSNRPPIRAEGRN----FPLPLPNKPRPPSPAEEE 415
            G  + S        +LP    QG   +  P +   G++    FP P  +   PP P E E
Sbjct: 1028 GKLNLS------GVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETE 1081



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 72/304 (23%), Positives = 104/304 (34%), Gaps = 55/304 (18%)

Query: 125 DGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQ 184
           +G    P      P    A  +  P+    +L     P  P       +I +      P 
Sbjct: 706 NGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPP 765

Query: 185 QPPVP-------PQRPMAALPPPPAGRNHSPL-----PPPQTNHEEPSRSRNHKTAKLPA 232
            PP+P       P +P+  +P P + +  +P+     PP  T    P++    K    PA
Sbjct: 766 PPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAK----KQPAFPA 821

Query: 233 PSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPS----IPAGRSLGEHLPKIQKPPLP 288
             I  S   P      P    P TL K+  F  KP      P    + +   +   PP P
Sbjct: 822 SYIPPSPPTP------PVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTP 875

Query: 289 PTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFP----- 343
           P  E    S PL     PVP      +        V  +P  QP+ +P+ S  FP     
Sbjct: 876 PAME----SQPL----KPVP-----ANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPE 922

Query: 344 -SRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNR-PPIRAEGRNFPLP 401
            S    P P +P+P+   P          P +AS  P  S  P  +     + G   P P
Sbjct: 923 SSLVFPPPPPSPVPAPPPPP---------PPTASPTPDKSGSPGKKTSKTSSPGGKKPPP 973

Query: 402 LPNK 405
            P +
Sbjct: 974 TPQR 977



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 57/259 (22%), Positives = 79/259 (30%), Gaps = 41/259 (15%)

Query: 176 RPPSGKTPQQPPVPPQRPMAALPPP-PAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPS 234
           R  S   P    VPP  P   +  P  A +   PLPPP                  P P 
Sbjct: 594 RMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPP------------------PPPP 635

Query: 235 IDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERH 294
                 PP      P    P      P F    +I   ++  +H   + KPP PP  +  
Sbjct: 636 PPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQ 695

Query: 295 ERS------------SPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPAL-LPMSSNT 341
                           P P   PP P       +       + Q   P P L +    + 
Sbjct: 696 SVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHI 755

Query: 342 FPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSAS---LPPYFSQG--PSNRPPIRAEGR 396
                  P P  P+P+   P A  +   + P   S   + P  +Q   P+  PP+    +
Sbjct: 756 TQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKK 815

Query: 397 NFPLPL----PNKPRPPSP 411
               P     P+ P PP P
Sbjct: 816 QPAFPASYIPPSPPTPPVP 834



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 50/230 (21%), Positives = 71/230 (30%), Gaps = 64/230 (27%)

Query: 202 AGRNHSPLPPPQTNHEEPSRSRNHKT------------------AKLPAPSIDRSTKPPL 243
           +G + S +P  Q+NH   S S    T                  A      ++ S+K  +
Sbjct: 536 SGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARM 595

Query: 244 DRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGK 303
           +    P+          PP S +P I    +  +  P +  PP PP         P P  
Sbjct: 596 ESMNRPYT------SLVPPLSPQPKIVTPYTASQPSPPLPPPPPPP---------PPPPP 640

Query: 304 KPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPL--PSSHMP 361
            PP P                   P P P+    S+ +      K S +  L   S H  
Sbjct: 641 PPPPP-------------------PPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSG 681

Query: 362 GAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSP 411
             F        QS S+ P     P+   P          P P  P PP+P
Sbjct: 682 ALFKPPTPPVMQSQSVKPQILVPPNGVVP----------PPPPPPPPPTP 721


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 79/308 (25%), Positives = 111/308 (36%), Gaps = 44/308 (14%)

Query: 109 EEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPN 168
           EE+  E    D++GE+  +     E   A  +++A   PPP            P  P P 
Sbjct: 365 EEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPS-----PPPPLPP 419

Query: 169 SNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTA 228
            ++     PP    P  PPV P  P+ + PPPPA       PPP       SR R  +  
Sbjct: 420 PST---SPPPPLCPPPPPPVSPP-PLPSPPPPPAQEEQEESPPPVV-PATCSRKRG-RPP 473

Query: 229 KLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLP 288
             P+   +R          +P    P T    PP  D P++    +    L  I++  +P
Sbjct: 474 LTPSQRAEREAARAGPEGTSPPTPTPSTATGGPP-EDSPTVAPKST--TFLKNIRQFIMP 530

Query: 289 PTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTK 348
             + R  R    P              RR  DED       P+P  + +S    P  +T 
Sbjct: 531 VVSARSSRVIKTP--------------RRFMDEDP------PKPPKVEVSPVLRPPITTS 570

Query: 349 PS-PMNPLPSSHMPGAFSESNSSFPQSASLP-PYFSQGPSNRPPIR--AEGRNFPLPLPN 404
           P  P  P P    P A        P S  +P P   +     P  R  +  R  P P P 
Sbjct: 571 PPVPQEPAPVPSPPRA------PTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPA 624

Query: 405 KPRPPSPA 412
            P PP+P+
Sbjct: 625 PPPPPAPS 632



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 74/295 (25%), Positives = 106/295 (35%), Gaps = 63/295 (21%)

Query: 132 NEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQ 191
           +EEEE   E++ D E     +E A+   ++PA               + K   + P PP 
Sbjct: 363 DEEEEKKEEEEKDKEGE-EKEERAVAEEMMPA---------------AEKEEAKLPPPPL 406

Query: 192 RPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFD 251
            P A  PPPP       LPPP T+   P           P P +   + PPL     P  
Sbjct: 407 TPPAPSPPPP-------LPPPSTSPPPP-------LCPPPPPPV---SPPPLPSPPPPPA 449

Query: 252 REPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPT--TERHERSSPLPGKKPPVPK 309
           +E     + PP    P +PA  S      K  +PPL P+   ER    +   G  PP P 
Sbjct: 450 QEEQE--ESPP----PVVPATCSR-----KRGRPPLTPSQRAEREAARAGPEGTSPPTPT 498

Query: 310 HGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHM---PGAFSE 366
                     D           P + P S+    +      P+    SS +   P  F +
Sbjct: 499 PSTATGGPPEDS----------PTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMD 548

Query: 367 SNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNEE 421
            +   P    + P      +  PP+  E    P P+P+ PR P+P      L E+
Sbjct: 549 EDPPKPPKVEVSPVLRPPITTSPPVPQE----PAPVPSPPRAPTPPSTPVPLPEK 599



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 55/219 (25%), Positives = 78/219 (35%), Gaps = 41/219 (18%)

Query: 149  PSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSP 208
            P++ E A +N  +   P P+S       PP G   + PP+        +  P A   HSP
Sbjct: 1792 PAHLEAAEENQTIVHSPAPSSE------PPGG---EDPPLDTD-----VLVPGAPERHSP 1837

Query: 209  L----PP--PQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPP 262
            +    PP  P +    P   R+   A++  P+   S +P    S  P             
Sbjct: 1838 IQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPL------------ 1885

Query: 263  FSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDED 322
                PS  +  SL  H+P +  P  P    R  R SPL  + P  P     P  + + + 
Sbjct: 1886 ----PSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPP--PSRWASPPLKTSPQL 1939

Query: 323  DVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMP 361
             V        AL P S    P     P+P  P P    P
Sbjct: 1940 RVPPPTSVVTALTPTSGELAP---PGPAPSPPPPEDLGP 1975



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 63/248 (25%), Positives = 86/248 (34%), Gaps = 50/248 (20%)

Query: 131 PNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPP------SGKTPQ 184
           P  +E APV        PPS              P P      +  P       + + P 
Sbjct: 572 PVPQEPAPVPSPPRAPTPPSTPV-----------PLPEKRRSILREPTFRWTSLTRELPP 620

Query: 185 QPPVPPQRPMAALPPPPAGRNHSP--LPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPP 242
            PP PP  P  + PP PA  +  P  L  PQ    E +  + +++   P         PP
Sbjct: 621 PPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSE-AHLKIYESVLTP---------PP 670

Query: 243 LDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLG--EHLPKIQKPPLPPTTERHERS--- 297
           L    AP   EP    + PP  D P+ P  R++G   HL   +  P+  T  + E S   
Sbjct: 671 LGAPEAP---EP----EPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHG 723

Query: 298 SPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPS 357
           +P     P        P +    +      P PQP L P  S         P  M PL  
Sbjct: 724 APALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPS---------PQQMPPLEK 774

Query: 358 SHMPGAFS 365
           + + G  S
Sbjct: 775 ARIAGVGS 782



 Score = 36.6 bits (83), Expect = 0.059
 Identities = 65/288 (22%), Positives = 89/288 (30%), Gaps = 62/288 (21%)

Query: 180  GKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRST 239
            G  P++  +PP  P+A    P  G   SP  P +T    P        +  PAP   +  
Sbjct: 2128 GAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPA 2187

Query: 240  -----------------------------KPPLDRSLAPFDREPFTLGKKPPFSDKPSIP 270
                                         +PPL  +++P     +TL   P     P + 
Sbjct: 2188 TSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVG 2247

Query: 271  AGRSLGEHLPKIQKPPL-----------PPTTERHERSSPLPGKKPPVPKHGWGPDRREN 319
              R      P    PPL           P    R +R S   G+ PP P     P     
Sbjct: 2248 VVRP----APPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAP---RL 2300

Query: 320  DEDDVHQRPLPQ-PAL-------LPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSF 371
            DED       PQ P L       + M + T         P  P      PG   E +   
Sbjct: 2301 DEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEP-AGEESPGPLQERSPLL 2359

Query: 372  PQSASLPPYFSQGPSNRPPIRAEGRNFPL---PLPNKPRPPSPAEEEN 416
            P     PP    GP   P +  E +          ++  PPSP ++EN
Sbjct: 2360 PLPEDGPPQVPDGP---PDLLLESQWHHYSGEASSSEEEPPSPDDKEN 2404



 Score = 30.0 bits (66), Expect = 5.5
 Identities = 47/192 (24%), Positives = 68/192 (35%), Gaps = 32/192 (16%)

Query: 133 EEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQ--PPVPP 190
           EEE +  E D +      +DE+   +S+  A            R P G+  +    P+PP
Sbjct: 110 EEESSDGESDEEEFQGFHSDEDVAPSSLRSALRSQRG------RAPRGRGRKHKTTPLPP 163

Query: 191 QRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPF 250
            R     P PP         P +   EE +        +L    + R+  P   RS A  
Sbjct: 164 PRLADVAPTPPK-------TPARKRGEEGTERMVQALTEL----LRRAQAPQAPRSRACE 212

Query: 251 DREPFTLGKKPPFSDKPSIPAGRS-----LGEHLPKIQKPPLPP--TTERHERSS----P 299
              P     +PP   +P+ P  R      + E    I KP  PP     +H+  S     
Sbjct: 213 PSTPRRSRGRPP--GRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKE 270

Query: 300 LPGKKPPVPKHG 311
            PG  P  P+ G
Sbjct: 271 GPGPGPGTPRRG 282



 Score = 29.6 bits (65), Expect = 7.2
 Identities = 37/133 (27%), Positives = 53/133 (39%), Gaps = 33/133 (24%)

Query: 221 RSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLP 280
           R R HKT  LP         PP    +AP    P T  +K    ++ +    ++L E L 
Sbjct: 152 RGRKHKTTPLP---------PPRLADVAP--TPPKTPARKR--GEEGTERMVQALTELLR 198

Query: 281 KIQKPPLP------PTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQ------RP 328
           + Q P  P      P+T R  R  P PG+         GP RR+     V +      +P
Sbjct: 199 RAQAPQAPRSRACEPSTPRRSRGRP-PGRPA-------GPCRRKQQAVVVAEAAVTIPKP 250

Query: 329 LPQPALLPMSSNT 341
            P P ++P+   T
Sbjct: 251 EPPPPVVPVKHQT 263


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 65/244 (26%), Positives = 88/244 (36%), Gaps = 36/244 (14%)

Query: 176 RPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEE--PSRSRNHKTAKLPAP 233
           RP  G  PQ+ P PP +P      PP G N S  PPP+    E  P +  N      P P
Sbjct: 40  RPQGGNQPQRTPPPPGKPEGR---PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRP 96

Query: 234 SIDRSTKPPL-DRSLAPFDREPFTLGKKPPFSDKPSIP---AGRSLGEHLPKIQKPPLPP 289
                  P   ++S  P           PP   KP  P    G       P+  KP  PP
Sbjct: 97  GKPEGQPPQGGNQSQGP-----------PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPP 145

Query: 290 TTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKP 349
               ++   P     PP P    GP  +  ++    Q P P P           ++S  P
Sbjct: 146 PQGGNQSQGP-----PPRPGKPEGPPPQGGNQS---QGPPPHPGKPEGPPPQGGNQSQGP 197

Query: 350 SPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPP 409
            P    P    P   ++S    P+     P   +GP ++   + +G   P P P KP+ P
Sbjct: 198 PPRPGKPEGPPPQGGNQSQGPPPR-----PGKPEGPPSQGGNKPQG---PPPHPGKPQGP 249

Query: 410 SPAE 413
            P E
Sbjct: 250 PPQE 253



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 84/318 (26%), Positives = 102/318 (32%), Gaps = 62/318 (19%)

Query: 114 ESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMY 173
           +S N+D   E+     S   E   P   +     PP            P KP        
Sbjct: 17  QSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPP-----------PGKPE------- 58

Query: 174 IDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAP 233
             RPP G    Q   PP RP     PPP G N S  PPP+    E    +    ++ P P
Sbjct: 59  -GRPPQGGNQSQG--PPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPP 115

Query: 234 SIDRSTKPPL---DRSLAPFDREPFTLGKKPPFSDKPSIP---AGRSLGEHLPKIQKPPL 287
              +   PP    ++S  P           PP   KP  P    G       P+  KP  
Sbjct: 116 RPGKPEGPPPQGGNQSQGP-----------PPRPGKPEGPPPQGGNQSQGPPPRPGKPEG 164

Query: 288 PPTT--ERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSR 345
           PP     + +   P PGK    P  G    +         + P PQ       S   P R
Sbjct: 165 PPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGG---NQSQGPPPR 221

Query: 346 STKP---------SPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGR 396
             KP          P  P P    P        + PQ    PP   QGP   PP    G 
Sbjct: 222 PGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPP-PPGRPQGP---PP---PGG 274

Query: 397 NFPLPLP---NKPRPPSP 411
           N   PLP    KP+ P P
Sbjct: 275 NPQQPLPPPAGKPQGPPP 292



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 55/204 (26%), Positives = 70/204 (34%), Gaps = 28/204 (13%)

Query: 114 ESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMY 173
           E P      +  G    P + E  P +     + PP    +       P  P P   +  
Sbjct: 121 EGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGK-------PEGPPPQGGNQS 173

Query: 174 IDRPPSGKTPQQPPV--------PPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNH 225
              PP    P+ PP         PP RP     PPP G N S  PPP+    E   S+  
Sbjct: 174 QGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGG 233

Query: 226 KTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLP----K 281
              + P P   +   PP      P  R P      PP   +   P G +  + LP    K
Sbjct: 234 NKPQGPPPHPGKPQGPPPQEGNKP-QRPP------PPGRPQGPPPPGGNPQQPLPPPAGK 286

Query: 282 IQKPPLPPTTERHERSSPLPGKKP 305
            Q PP PP   R  R  P  G+ P
Sbjct: 287 PQGPPPPPQGGRPHR--PPQGQPP 308


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 85/374 (22%), Positives = 141/374 (37%), Gaps = 91/374 (24%)

Query: 78    RRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEA 137
             ++ +   KP VP  PE  ES   +      +EE +  +P ++          +P EE+  
Sbjct: 10780 KKPVLEEKPAVP-VPERAESPPPE-----VYEEPEEIAPEEEI---------APEEEKPV 10824

Query: 138   PVEDDADYE-PPPSNDEEALQNSILPAKPFPNSNSMYIDRP--PSGKTPQQPPVPPQRPM 194
             PV ++ + E PPP+  EE       P K  P      I +P  P  K P+   V  +  +
Sbjct: 10825 PVAEEEEPEVPPPAVPEE-------PKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKL 10877

Query: 195   AALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPA-PSIDRSTK-PPLD-------- 244
                PPPP      P PP +   E+  + +     K+P  P +    +  PL         
Sbjct: 10878 KPRPPPPP-----PAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKV 10932

Query: 245   RSLAPFDREPF--------TLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLP-------- 288
             R L P +R+P         ++ +K P  ++P +   +      P + +PP P        
Sbjct: 10933 RKLLP-ERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEV 10991

Query: 289   PTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTK 348
             PT  + ER  P P K P +                  +  +P PA  P        ++ K
Sbjct: 10992 PTVTKRERKIPEPTKVPEI------------------KPAIPLPAPEPKPKPEAEVKTIK 11033

Query: 349   PSPMNPLPSS-----HMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLP 403
             P P+ P P+       +P    ++ +  P+  +  P        + PI+   +  P P+ 
Sbjct: 11034 PPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKP--------KGPIKGVPKKTPSPIE 11085

Query: 404   ---NKPRPPSPAEE 414
                 K RP S  E+
Sbjct: 11086 AERRKLRPGSGGEK 11099



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 82/376 (21%), Positives = 129/376 (34%), Gaps = 61/376 (16%)

Query: 76    EERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEE- 134
             +ER  +   + +V   PEE E HE +      FEE ++    +    E     E    E 
Sbjct: 10362 KERLELEVVEAEVEEIPEEEEFHEVEE----YFEEGEFHEVEEFIKLEQHRVEEEHRVEK 10417

Query: 135   --------EEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSG------ 180
                     E   VE     + PP   E  +   I+P K  P +  +    PP+       
Sbjct: 10418 VHRVIEVFEAEEVEVFEKPKAPPKGPE--ISEKIIPPKK-PPTKVVPRKEPPAKVPEVPK 10474

Query: 181   --------KTPQQPPVPPQRPMAALPP-----------PPAGRNHSPLPPPQTNHEEPSR 221
                     + P++P VPP +    LPP           PPA +   P  PP    E P  
Sbjct: 10475 KIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKK---PEAPPPKVPEAPKE 10531

Query: 222   SRNHKTAKLP---APSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEH 278
                 K   +P    P +  +  P + ++  P  + P  +  KP  S  P +P      E 
Sbjct: 10532 VVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPE-SPPPEVPEAPK--EV 10588

Query: 279   LPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMS 338
             +P+ + P  PP     ++    P K P  PK    P+++        ++P   P  +P  
Sbjct: 10589 VPEKKVPAAPP-----KKPEVTPVKVPEAPKE-VVPEKKVPVPPP--KKPEVPPTKVPEV 10640

Query: 339   SNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNF 398
                       P  + P P S  P  F E      +           P+  P +    +  
Sbjct: 10641 PKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKK- 10699

Query: 399   PLPLPNKPRPPSPAEE 414
               P+P K  P   A++
Sbjct: 10700 --PVPEKKAPAVVAKK 10713



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 79/320 (24%), Positives = 116/320 (36%), Gaps = 58/320 (18%)

Query: 129   ESPNE---EEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQ 185
             E+P E   E++ P       E  P    EA    ++P K  P       + PP+ K P+ 
Sbjct: 10583 EAPKEVVPEKKVPAAPPKKPEVTPVKVPEA-PKEVVPEKKVPVPPPKKPEVPPT-KVPEV 10640

Query: 186   PPV--PPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKL---PAPSID-RST 239
             P V  P ++   A+PP P        PPP+   E    +     A++   P P+   + T
Sbjct: 10641 PKVAVPEKKVPEAIPPKPES------PPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVT 10694

Query: 240   KPPLDRSLAPFDREPFTLGKKP--PFSDKPSIPAGRSLGEHLPKI--QKPPLPPTTERHE 295
              PP  +   P  + P  + KKP  P    P +P      + +P +  +KP  PP      
Sbjct: 10695 VPP--KKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEV 10752

Query: 296   RSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPS-PMNP 354
                 +P KK  VPK                 +P   PA +P      P    KP+ P+  
Sbjct: 10753 PKEVVPEKKVAVPK-----------------KPEVPPAKVPEVPKK-PVLEEKPAVPVPE 10794

Query: 355   LPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPA-- 412
                S  P  + E     P+    P               E +  P+    +P  P PA  
Sbjct: 10795 RAESPPPEVYEEPEEIAPEEEIAPE--------------EEKPVPVAEEEEPEVPPPAVP 10840

Query: 413   EEENSLNEEWYVSYITRPEA 432
             EE   +  E  V  I +PEA
Sbjct: 10841 EEPKKIIPEKKVPVIKKPEA 10860



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 75/346 (21%), Positives = 112/346 (32%), Gaps = 76/346 (21%)

Query: 129   ESPNEEEEAPVEDDADYEPPPSNDEEAL-----QNSILPAKPFPNSNSMYIDRPPSGKTP 183
             ESP  E     E+ A  EPP    EE       Q ++ P KP P   +  +      K P
Sbjct: 10659 ESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAV----VAKKP 10714

Query: 184   QQPPVP-PQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPP 242
             + PPV  P+ P   +P         PL  P+     P++        +P   +    KP 
Sbjct: 10715 ELPPVKVPEVPKEVVPEKKV-----PLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPE 10769

Query: 243   LDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKI-------------------- 282
             +  +  P       + KKP   +KP++P         P++                    
Sbjct: 10770 VPPAKVP------EVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKP 10823

Query: 283   ------QKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQ------RPLP 330
                   ++P +PP     E    +P KK PV K    P  +E + + V +      RP P
Sbjct: 10824 VPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPP 10883

Query: 331   QPALLPMSS--------NTFPSRSTKPSPMNP----LPSSHMPGAFSESNSSFP------ 372
              P   P              P +     P  P    L    +PG   +     P      
Sbjct: 10884 PPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEP 10943

Query: 373   -QSASLPPYFSQGPSNRPPIRAEGRNF---PLPLPNKPRPPSPAEE 414
              +   L     + P    P + E +       P   +P PP P EE
Sbjct: 10944 KEEVVLKSVLRKRPEEEEP-KVEPKKLEKVKKPAVPEPPPPKPVEE 10988



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 82/378 (21%), Positives = 132/378 (34%), Gaps = 63/378 (16%)

Query: 84    RKPQVPR--------FPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDD---------- 125
             R P+VP+        F EE  +H E+   +   EE++Y    ++   E++          
Sbjct: 9895  RVPEVPKELEPEEVAFEEEVVTHVEE---YLVEEEEEYIHEEEEFITEEEVVPVIPVKVP 9951

Query: 126   GDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYI--DRPPSGKTP 183
                  P  EE+ PV      E PP+   E      +P KP      +    ++PP  K P
Sbjct: 9952  EVPRKPVPEEKKPVPVPKKKEAPPAKVPE------VPKKPEEKVPVLIPKKEKPPPAKVP 10005

Query: 184   QQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAP---SIDRSTK 240
             + P  P       +P P          PP    E P +    K   +PAP       +  
Sbjct: 10006 EVPKKPVPEEKVPVPVPKKVE-----APPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKV 10060

Query: 241   PPLDRSLAPFDREPFTLGKK---PPFSDKPSIPAGRS---LGEHLPK-----IQKPPLPP 289
             P + + L P +++P  + KK   PP    P +P  R    +   LP+      ++  +P 
Sbjct: 10061 PEVPKKLIPEEKKPTPVPKKVEAPP----PKVPKKREPVPVPVALPQEEEVLFEEEIVPE 10116

Query: 290   TTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSR---- 345
                  E    LP ++  +P+        E    +  + P P+   +P      P      
Sbjct: 10117 EEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVP-PEEEYVPEEEEFVPEEEVLP 10175

Query: 346   STKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNK 405
               KP    P P   +    +E     P+    PP          P + E +   LP   +
Sbjct: 10176 EVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPP----AKVPEVPKKVEEKRIILPKEEE 10231

Query: 406   PRPPSPAE--EENSLNEE 421
               P    E  EE  ++EE
Sbjct: 10232 VLPVEVTEEPEEEPISEE 10249



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 92/440 (20%), Positives = 150/440 (34%), Gaps = 90/440 (20%)

Query: 62   VPILSKLSQ---EINKN---EERRSIFTRKPQ--VPRFPEETESHEEDNGGWSSFEEDD- 112
            VP+  K      E++K    EE+R +   K    VP+  E T         WS  EE++ 
Sbjct: 9444 VPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEG 9503

Query: 113  ------YESPNDDQDGEDDGDYESPNEEEEAPVEDDADY-----EPPPSNDEEALQNSIL 161
                   E   ++++  +  +YE   E EE  VE+         E  P+   E  +  I+
Sbjct: 9504 VSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIV 9563

Query: 162  PAKPFPNSNSMYIDRPPSGKTPQQP-----------PVP----------PQRPMAALP-- 198
                 P      I+ PP  K P+ P           PVP          P+ P   +P  
Sbjct: 9564 LKPKIPAK----IEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEK 9619

Query: 199  --PPPAGRNHSPLPPPQTN-HEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPF 255
              PP   +   PLP   T  H + ++      A     +  ++  P   +   P ++   
Sbjct: 9620 KVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEK--- 9676

Query: 256  TLGKKPPFSDKPS---------IPAGRSLGEHLPKIQKPPLPPTT--ERHERSSPLPGKK 304
             L  KP   ++P          +     +    PK +  P+   T  E  ER+  L  + 
Sbjct: 9677 VLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEA 9736

Query: 305  PPVPKHGWGPDRREND-----------EDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMN 353
              V +     +  E D           E D ++    +          + +   KP P+ 
Sbjct: 9737 VSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVK 9796

Query: 354  PLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAE 413
            P+P   +P        + P++          P  + P+       P+P   KP PP   E
Sbjct: 9797 PVPEEPVP--------TKPKAPPAKVLKKAVPEEKVPV-------PIPKKLKPPPPKVPE 9841

Query: 414  EENSLNEEWYVSYITRPEAE 433
            E   + EE     IT+ E E
Sbjct: 9842 EPKKVFEEKIRISITKREKE 9861



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 89/439 (20%), Positives = 146/439 (33%), Gaps = 101/439 (23%)

Query: 70    QEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYE 129
             +E+   EE+   +T + +      E E  E +   +  FEE +     D  +  ++ +YE
Sbjct: 9718  KEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYE 9777

Query: 130   SPNEEEE-----------APVEDDADYEPPPSNDEEALQNSILPAK-PFPNSNSMYIDRP 177
                E EE            PV ++     P +   + L+ ++   K P P    +   +P
Sbjct: 9778  RYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKL---KP 9834

Query: 178   PSGKTPQQP---------------------------PVPPQRPMAALPPPPAGRNHSP-- 208
             P  K P++P                           P+ P+R +A    P   +  +P  
Sbjct: 9835  PPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPV 9894

Query: 209   --------LPPPQTNHEEP-----------------SRSRNHKTAKLPAPSIDRSTKPPL 243
                     L P +   EE                         T +   P I     P +
Sbjct: 9895  RVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKV-PEV 9953

Query: 244   DRSLAPFDREPFTLGKK--PPFSDKPSIP--AGRSLGEHLPKIQKPPLPPTTERHERSSP 299
              R   P +++P  + KK   P +  P +P      +   +PK +KPP     E  ++  P
Sbjct: 9954  PRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVP 10013

Query: 300   LPGKKPPVPKHGWGPDRR--ENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPS 357
                   PVPK    P  +  E  +  V ++ +P PA   + +   P       P   +P 
Sbjct: 10014 EEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEA---PPAKVPEVPKKLIPE 10070

Query: 358   SHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENS 417
                P       +  P+    PP   + P  R P+       P+P+        P EEE  
Sbjct: 10071 EKKP-------TPVPKKVEAPP--PKVPKKREPV-------PVPV------ALPQEEEVL 10108

Query: 418   LNEEWYVSYITRPEAEAAL 436
               EE        PE E  L
Sbjct: 10109 FEEEIVPEEEVLPEEEEVL 10127



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 41/173 (23%), Positives = 66/173 (38%), Gaps = 21/173 (12%)

Query: 146   EPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRN 205
             E  P   EE +  S+L  +P      +   +    K P  P  PP +P+  +  P   + 
Sbjct: 10938 ERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKR 10997

Query: 206   HSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLD-RSLAPFDREPF--------- 255
                +P       EP++    K A +P P+ +   KP  + +++ P   EP          
Sbjct: 10998 ERKIP-------EPTKVPEIKPA-IPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVT 11049

Query: 256   --TLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPP 306
                +GKK   +  P   A +  G      +K P P   ER +      G+KPP
Sbjct: 11050 VPVVGKKAE-AKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPP 11101



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 68/372 (18%), Positives = 129/372 (34%), Gaps = 35/372 (9%)

Query: 93   EETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSND 152
            EE + + E   G+   EE+  E+  + +  +   +    + E + P +      PPP   
Sbjct: 9121 EEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPP-- 9178

Query: 153  EEALQNSILPAKPFPNSNSMYIDRPPSGKTPQ-QPPVPPQRPMAALPPPPAGRNHSPLPP 211
             + ++  ++  K    S  M  ++    K P+    + PQ+P       P       +  
Sbjct: 9179 -KVIKKPVIE-KIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRT----PVQEEVIEVKV 9232

Query: 212  PQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKK----PPFSDKP 267
            P  + ++   S                T P + + +   ++    + K+    P   + P
Sbjct: 9233 PAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELP 9292

Query: 268  SIPAGRSLGE-HLPKIQKPPLPPTTERHERSSPLPGKKPPVP---KHGWGPDRRENDEDD 323
              PA   +    +PK  +PP P   E  ++  P+P +K PVP   K    P +      +
Sbjct: 9293 EKPAPEEVAPVPIPKKVEPPAPKVPEVPKK--PVPEEKKPVPVPKKEPAAPPK----VPE 9346

Query: 324  VHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYF-- 381
            V ++P+P+  +        P    K +P   +P         E  +   Q    PP    
Sbjct: 9347 VPKKPVPEEKI------PVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVP 9400

Query: 382  ----SQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALR 437
                 + P  R P+  +    P P      P  P  EE              P AE + +
Sbjct: 9401 EIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKK 9460

Query: 438  KINQDGTFLVRD 449
             + ++  F+  +
Sbjct: 9461 TVVEEKRFVAEE 9472



 Score = 33.1 bits (74), Expect = 0.65
 Identities = 61/265 (23%), Positives = 92/265 (34%), Gaps = 49/265 (18%)

Query: 56    KFPKLR--VPILSKLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDY 113
             K PK R  VP+   L QE     E   +    P+    PEE E   E+        E++ 
Sbjct: 10087 KVPKKREPVPVPVALPQEEEVLFEEEIV----PEEEVLPEEEEVLPEEE---EVLPEEEE 10139

Query: 114   ESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFP------ 167
               P ++         E P EEEE P E++   E      EE +   + P  P P      
Sbjct: 10140 VLPEEE---------EIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEI 10190

Query: 168   ----NSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSR 223
                     + I +       + P VP +     +  P   +    LP   T   E     
Sbjct: 10191 KKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILP---KEEEVLPVEVTEEPEEEPIS 10247

Query: 224   NHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQ 283
               +  + P PSI+          +AP  R P  + K  P +  P +P          K++
Sbjct: 10248 EEEIPEEP-PSIEEV------EEVAP-PRVPEVIKKAVPEAPTP-VP---------KKVE 10289

Query: 284   KPPLPPTTERHERSSPLPGKKPPVP 308
              PP   + +  E   P+P +K   P
Sbjct: 10290 APPAKVSKKIPEEKVPVPVQKKEAP 10314


>gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo
           sapiens]
          Length = 245

 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 58/214 (27%), Positives = 73/214 (34%), Gaps = 43/214 (20%)

Query: 149 PSNDEEALQNSILPAK-PF-PNSNSMYIDRPPSGKTPQQP-PVPPQRPMAALPPPPAGRN 205
           PS+    L  S  P+  PF P    MY   PP+G  P  P P PP  P     PPP G  
Sbjct: 46  PSSVPSGLPPSATPSTVPFGPAPTGMYPSVPPTGPPPGPPAPFPPSGPSC---PPPGGPY 102

Query: 206 HSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSD 265
            +P  P       P  +  + T  +P P + R    P D         P   G   P+  
Sbjct: 103 PAPTVPG------PGPTGPYPTPNMPFPELPRPYGAPTD---------PAAAGPLGPWGS 147

Query: 266 KPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVP-----KHGWGPDRREND 320
             S P    +G   P    P   P           PG  PPVP        WGP      
Sbjct: 148 MSSGPWAPGMGGQYPTPNMPYPSPGPYPAPPPPQAPGAAPPVPWGTVPPGAWGP------ 201

Query: 321 EDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNP 354
                      PA  P  + ++P+    P+P NP
Sbjct: 202 -----------PAPYPAPTGSYPTPGLYPTPSNP 224



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 35/117 (29%), Positives = 45/117 (38%), Gaps = 8/117 (6%)

Query: 296 RSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPL 355
           ++S +   KP  P  GW      N+       P   P+ LP S+ T  +    P+P    
Sbjct: 18  KTSAVSNTKPGQPPQGWPGSNPWNNPS----APSSVPSGLPPSA-TPSTVPFGPAPTGMY 72

Query: 356 PSSHMPGAFSESNSSFPQSA-SLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSP 411
           PS    G      + FP S  S PP    GP   P +   G   P P PN P P  P
Sbjct: 73  PSVPPTGPPPGPPAPFPPSGPSCPP--PGGPYPAPTVPGPGPTGPYPTPNMPFPELP 127


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
           sapiens]
          Length = 1362

 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 77/338 (22%), Positives = 121/338 (35%), Gaps = 61/338 (18%)

Query: 109 EEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPN 168
           E+ D  + +    G    + ES +E   +  ED ++ E  P + ++         K   +
Sbjct: 684 EKVDVIAGSSKMKGFSSSESESSSESSSSDSED-SETEMAPKSKKKGHPGR--EQKKHHH 740

Query: 169 SNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTA 228
            +   + + P+   PQQPP PPQ+P    PPPP  +   P PPP                
Sbjct: 741 HHHQQMQQAPA-PVPQQPPPPPQQPP---PPPPPQQQQQPPPPP---------------- 780

Query: 229 KLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGR-----------SLGE 277
             P PS+ +   P +  S  PF      +  +P        P G             L  
Sbjct: 781 --PPPSMPQQAAPAMKSSPPPFIATQVPV-LEPQLPGSVFDPIGHFTQPILHLPQPELPP 837

Query: 278 HLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPM 337
           HLP+  +   PP   +H   SP P     +P+    P R  N    +  +P   PA+ P 
Sbjct: 838 HLPQPPEHSTPPHLNQHAVVSP-PALHNALPQQ---PSRPSNRAAALPPKPARPPAVSPA 893

Query: 338 SSNT----FPSRSTKPS--------PMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQG- 384
            + T     P  +  P         P  PL S  M     +     P +  LP    Q  
Sbjct: 894 LTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQ 953

Query: 385 ------PSNRPPIRAEGRNFPLPLPNKPRPPSPAEEEN 416
                 P   P ++ + +  P P P  P+P  P ++++
Sbjct: 954 PPPPLPPPPHPSVQQQLQQQP-PPPPPPQPQPPPQQQH 990



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 86/385 (22%), Positives = 137/385 (35%), Gaps = 61/385 (15%)

Query: 139  VEDDADYEPPPSNDEEALQ----NSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPM 194
            +ED+    PP ++ +  L       + P  P   S  +    PP    P  P V  Q   
Sbjct: 913  LEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQ 972

Query: 195  AALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREP 254
               PPPP      P PPPQ  H+ P R  + +    P        +PP  +   P    P
Sbjct: 973  QPPPPPPP----QPQPPPQQQHQPPPRPVHLQ----PMQFSTHIQQPPPPQGQQPPHPPP 1024

Query: 255  FTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGP 314
               G++PP   +P+ P       H P+  K     T    E  SPL    P + +     
Sbjct: 1025 ---GQQPP-PPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQF---- 1076

Query: 315  DRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSS--HMPGAFSESNS--- 369
                  +   HQ P PQ  + P       +   +P P+  +     H P   SE  S   
Sbjct: 1077 ------QSLTHQSP-PQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSL 1129

Query: 370  -----SFPQSASLPPYFSQGPS------NRPPIRAEGRNFPLP-LPNKPR-------PPS 410
                   P+S   P +  Q P        RP IR   +N P P  P+K +       P +
Sbjct: 1130 RPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVA 1189

Query: 411  PAEEENSLNEEWYVSYITR-PEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKV 469
            P ++    N   + S + + P   ++  K + D     R ++++            ++K 
Sbjct: 1190 PKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEE---------REKA 1240

Query: 470  YNIQIRYQKESQVYLLGTGLRGKED 494
               Q  + ++ +  L    +R +ED
Sbjct: 1241 LKAQAEHAEKEKERLRQERMRSRED 1265



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 29/113 (25%), Positives = 42/113 (37%), Gaps = 10/113 (8%)

Query: 165 PFPN-SNSMYIDRPPSGKTPQQP-----PVPPQRPMAALPPPPAGRNHSPL----PPPQT 214
           PFP  +  + +  P     P QP     PVPPQ      P P   ++H P+    P P  
Sbjct: 224 PFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVK 283

Query: 215 NHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKP 267
             +   R  +  T     P  +  + PP  ++     R   +   KPP  D P
Sbjct: 284 TKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVP 336



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 49/217 (22%), Positives = 69/217 (31%), Gaps = 48/217 (22%)

Query: 129 ESPNEEEEAPV----------EDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPP 178
           E P EE E  +          ++    +P  S      Q S  P    P  N   +   P
Sbjct: 163 ELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATP 222

Query: 179 SGKTPQQPPVPPQRPMAALPPPPAGRNHSPLP----PPQTNHEEPSRSRNHKTAKLPAPS 234
                  P +  Q P+  + PP   +   P+P    PP     +P +S     A  P P 
Sbjct: 223 HPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPV 282

Query: 235 IDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERH 294
               TK  + R        P T+    P  + PS+               PP P TT+  
Sbjct: 283 ---KTKKGVKRKAD--TTTPTTI---DPIHEPPSL---------------PPEPKTTKLG 319

Query: 295 ERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQ 331
           +R       KPP           + D  D  Q P P+
Sbjct: 320 QRRESSRPVKPP-----------KKDVPDSQQHPAPE 345



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 29/138 (21%), Positives = 50/138 (36%), Gaps = 3/138 (2%)

Query: 186 PPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDR 245
           P VPP   + A PP  +  +        ++ ++    R  + A+L      ++    L  
Sbjct: 471 PAVPPPTKVVA-PPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQL--KAVHEQLAA 527

Query: 246 SLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKP 305
              P   +P    K      K        + E+     K P P  T+++  S+    KK 
Sbjct: 528 LSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKE 587

Query: 306 PVPKHGWGPDRRENDEDD 323
           P P     P   E++E+D
Sbjct: 588 PAPMKSKPPPTYESEEED 605


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 91/365 (24%), Positives = 132/365 (36%), Gaps = 58/365 (15%)

Query: 67  KLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGE-DD 125
           K S +  K E    + + K Q  +   +TE  E D       +  +   PN   +GE + 
Sbjct: 76  KKSAKKVKEEASSPLKSNKRQREKVASDTE--EADRTSSKKTKTQEISRPNSPSEGEGES 133

Query: 126 GDYESPNEEEEAPVED-DADYE------PPPSNDEE----ALQNSILPAKPFPNSNSMYI 174
            D  S N+E  +  +D D D        P P ++E     + Q  +L A+P P   +   
Sbjct: 134 SDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQP-PALQA--- 189

Query: 175 DRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPS 234
              P+G TP     PP  P    P P       P     T  + P++ +   TA +P   
Sbjct: 190 ---PTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQ-APTAPVPHTH 245

Query: 235 IDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERH 294
           I ++               P    ++PP    P  P+             PPL P T   
Sbjct: 246 IQQA---------------PALHPQRPPSPHPPPHPS-----------PHPPLQPLTGSA 279

Query: 295 ERSSPLPGKKPPVPKHGWGPDRREN-DEDDVHQRP-LPQP-ALLPMSSNTFPSRSTKPSP 351
            + S     +PP+  HG GP    +     + Q P  PQP  L P +S       T P+ 
Sbjct: 280 GQPSAPSHAQPPL--HGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAA 337

Query: 352 MNPLPSSHMPGAFSESNSSF-PQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRP-- 408
             P  S  +P + S   S   P+   LPP     P  +PP        P P  +K  P  
Sbjct: 338 AYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL 397

Query: 409 --PSP 411
             PSP
Sbjct: 398 SGPSP 402



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 51/218 (23%), Positives = 71/218 (32%), Gaps = 39/218 (17%)

Query: 136 EAPVEDDADYEPPPSNDEEALQNSILPAKP-FPNSNSMYIDRPPSGKTPQQPPVPPQRPM 194
           + P      + P  S       N+ LP  P     +S+    PPS   P    +P  +P+
Sbjct: 384 QLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPL 443

Query: 195 AALPPPPAGRNHSP-LPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDRE 253
            + P  P G   S  LPPP  +H        H+ A  P                 PF + 
Sbjct: 444 PSSPAQPPGLTQSQNLPPPPASHPPTGL---HQVAPQP-----------------PFAQH 483

Query: 254 PFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWG 313
           PF  G  PP +  P+ P+  +         +PP           S   G   P+P     
Sbjct: 484 PFVPGGPPPIT-PPTCPSTSTPPAGPGTSAQPPCSGAAA--SGGSIAGGSSCPLPT---- 536

Query: 314 PDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSP 351
              +E   DD  +   P P          P RS  P P
Sbjct: 537 VQIKEEALDDAEEPESPPP----------PPRSPSPEP 564



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 55/237 (23%), Positives = 77/237 (32%), Gaps = 48/237 (20%)

Query: 173 YIDRPPSGKTPQQP-PVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLP 231
           +I  PP+   PQ P P   + P     P P   N + LPPP       S S +H  +  P
Sbjct: 373 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN-ANLPPPPALKPLSSLSTHHPPSAHP 431

Query: 232 APSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTT 291
                    PPL             + +  P    P+ P G +  ++LP           
Sbjct: 432 ---------PPLQ-----------LMPQSQPLPSSPAQPPGLTQSQNLP----------- 460

Query: 292 ERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSP 351
                  P P   PP   H   P      +    Q P       P++  T PS ST P+ 
Sbjct: 461 -------PPPASHPPTGLHQVAP------QPPFAQHPFVPGGPPPITPPTCPSTSTPPA- 506

Query: 352 MNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRP 408
             P  S+  P + + ++       S  P  +          AE    P P P  P P
Sbjct: 507 -GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSP 562


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.133    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,193,250
Number of Sequences: 37866
Number of extensions: 2060615
Number of successful extensions: 26727
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 496
Number of HSP's successfully gapped in prelim test: 1583
Number of HSP's that attempted gapping in prelim test: 11823
Number of HSP's gapped (non-prelim): 8692
length of query: 533
length of database: 18,247,518
effective HSP length: 107
effective length of query: 426
effective length of database: 14,195,856
effective search space: 6047434656
effective search space used: 6047434656
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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