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Search of human proteins with 4885457
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4885457 mothers against decapentaplegic homolog 4 [Homo
sapiens]
(552 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens] 1153 0.0
gi|187828357 SMAD family member 9 isoform a [Homo sapiens] 275 8e-74
gi|5174513 mothers against decapentaplegic homolog 3 isoform 1 [... 272 5e-73
gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens] 267 2e-71
gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens] 267 2e-71
gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens] 267 2e-71
gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens] 265 8e-71
gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens] 265 8e-71
gi|5174519 SMAD family member 9 isoform b [Homo sapiens] 236 5e-62
gi|223029442 mothers against decapentaplegic homolog 3 isoform 3... 205 1e-52
gi|223029440 mothers against decapentaplegic homolog 3 isoform 2... 180 3e-45
gi|223029444 mothers against decapentaplegic homolog 3 isoform 4... 171 1e-42
gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens] 168 1e-41
gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens] 168 1e-41
gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo sapi... 168 1e-41
gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens] 99 1e-20
gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens] 99 1e-20
gi|5174517 SMAD family member 7 [Homo sapiens] 88 2e-17
gi|5453936 POU class 3 homeobox 3 [Homo sapiens] 43 9e-04
gi|153792780 additional sex combs like 2 [Homo sapiens] 42 0.001
gi|50345831 forkhead box J3 [Homo sapiens] 42 0.002
gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens] 39 0.016
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 37 0.047
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 37 0.047
gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens] 37 0.062
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 36 0.10
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 36 0.10
gi|151301154 mucin 6, gastric [Homo sapiens] 36 0.10
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 36 0.10
gi|34452686 ring finger protein, LIM domain interacting [Homo sa... 35 0.14
>gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]
Length = 552
Score = 1153 bits (2982), Expect = 0.0
Identities = 552/552 (100%), Positives = 552/552 (100%)
Query: 1 MDNMSITNTPTSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITA 60
MDNMSITNTPTSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITA
Sbjct: 1 MDNMSITNTPTSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITA 60
Query: 61 ITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFD 120
ITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFD
Sbjct: 61 ITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFD 120
Query: 121 LKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQ 180
LKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQ
Sbjct: 121 LKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQ 180
Query: 181 TIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGLLQI 240
TIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGLLQI
Sbjct: 181 TIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGLLQI 240
Query: 241 ASGPQPGQQQNGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGH 300
ASGPQPGQQQNGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGH
Sbjct: 241 ASGPQPGQQQNGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGH 300
Query: 301 YWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGD 360
YWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGD
Sbjct: 301 YWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGD 360
Query: 361 RFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGR 420
RFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGR
Sbjct: 361 RFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGR 420
Query: 421 APGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAP 480
APGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAP
Sbjct: 421 APGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAP 480
Query: 481 AISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVL 540
AISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVL
Sbjct: 481 AISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVL 540
Query: 541 HTMPIADPQPLD 552
HTMPIADPQPLD
Sbjct: 541 HTMPIADPQPLD 552
>gi|187828357 SMAD family member 9 isoform a [Homo sapiens]
Length = 467
Score = 275 bits (703), Expect = 8e-74
Identities = 193/534 (36%), Positives = 265/534 (49%), Gaps = 105/534 (19%)
Query: 20 VHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLD 79
V L+ +QG E E +A++A++SLVKKLK+KK +D L A++ G PSKCVTI R+LD
Sbjct: 18 VKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPG-QPSKCVTIPRSLD 76
Query: 80 GRLQVAGRKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138
GRLQV+ RKG PHVIY R+WRWPDL +ELK ++ C++ F K VC+NPYHY RV +
Sbjct: 77 GRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVET 136
Query: 139 PGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQHP--PSNRASTETYS 196
P + P ++ + ++ Q SL + S P P N +++
Sbjct: 137 PVL-----------PPVLVPRHS---EYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQ 182
Query: 197 TP--ALLAPSESNATS----TANFPNIPVASTSQPASILGGSHSEGLLQIASGPQPGQQQ 250
P + L PS S+A S TA++P+ P S S+P S Q
Sbjct: 183 QPPCSALPPSPSHAFSQSPCTASYPHSP-GSPSEPES--------------------PYQ 221
Query: 251 NGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGHYWPVHNELAF 310
+ P YH + + T + H + G + PV E
Sbjct: 222 HSVDTPPLPYHATEASETQSGQPVDATAD----------RHVVLSIPNGDFRPVCYE--- 268
Query: 311 QPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGG-DRFCLGQLSN 369
P++WCS+AY+E++ +VGETF+ S V +DG+ DPS +RFCLG LSN
Sbjct: 269 --------EPQHWCSVAYYELNNRVGETFQASSRS--VLIDGFTDPSNNRNRFCLGLLSN 318
Query: 370 VHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKI 429
V+R IE R HIGKGV L G G+V+ C+SD ++FVQS + + G P V KI
Sbjct: 319 VNRNSTIENTRRHIGKGVHLYYVG-GEVYAECVSDSSIFVQSRNCNYQHGFHPA-TVCKI 376
Query: 430 YPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAG 489
+KVF+ Q A A + V
Sbjct: 377 PSGCSLKVFN--------NQLFAQLLAQSVHHGFEV------------------------ 404
Query: 490 IGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 543
V +L ++C +RMSFVKGWG +Y RQ + TPCWIEIHLH LQ LD+VL M
Sbjct: 405 --VYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQM 456
>gi|5174513 mothers against decapentaplegic homolog 3 isoform 1
[Homo sapiens]
Length = 425
Score = 272 bits (696), Expect = 5e-73
Identities = 189/518 (36%), Positives = 253/518 (48%), Gaps = 128/518 (24%)
Query: 28 QGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGR 87
Q G+ E + ++A++SLVKKLK K +LD L AITT + +KC+TI R+LDGRLQV+ R
Sbjct: 23 QNGQEEKWCEKAVKSLVKKLK-KTGQLDELEKAITTQNVN-TKCITIPRSLDGRLQVSHR 80
Query: 88 KGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERVVSPGIDLSGL 146
KG PHVIY RLWRWPDLH +EL+ ++ C++AF++K D VCVNPYHY+RV +P + +
Sbjct: 81 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLV 140
Query: 147 TLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQHPPSNRASTETYSTPALLAPSES 206
+ P+ D+Y H P N
Sbjct: 141 PRHTEIPAEFPPLDDYSHSI-------------------PEN------------------ 163
Query: 207 NATSTANFPNIPVASTSQPASILGGSHSEGLLQIASGPQPGQ-QQNGFTGQPATYHHNST 265
T+ PA I E I P PG ++G T H +
Sbjct: 164 ---------------TNFPAGI------EPQSNIPETPPPGYLSEDGETSD----HQMNH 198
Query: 266 TTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGHYWPVHNELAFQPPISNHPAPEYWCS 325
+ GS P P H N LQ P PA +WCS
Sbjct: 199 SMDAGSPNLSPNPMSPAHNNLDLQ----------------------PVTYCEPA--FWCS 234
Query: 326 IAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGK 385
I+Y+E++ +VGETF +S P +TVDG+ DPS +RFCLG LSNV+R A+E R HIG+
Sbjct: 235 ISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGR 292
Query: 386 GVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHR 445
GV+L G G+V+ CLSD A+FVQS ++ G P V KI P +K+F+
Sbjct: 293 GVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHPA-TVCKIPPGCNLKIFN------ 344
Query: 446 QMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGIGVDDLRRLCILRMSF 505
Q+ A A + Q V L R+C +RMSF
Sbjct: 345 --NQEFAALLAQSVNQGFE--------------------------AVYQLTRMCTIRMSF 376
Query: 506 VKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 543
VKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL M
Sbjct: 377 VKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM 414
>gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]
Length = 465
Score = 267 bits (682), Expect = 2e-71
Identities = 194/536 (36%), Positives = 268/536 (50%), Gaps = 108/536 (20%)
Query: 20 VHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLD 79
V L+ +QG E E +A++A+++LVKKLK+KK ++ L A+++ G PSKCVTI R+LD
Sbjct: 15 VKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG-QPSKCVTIPRSLD 73
Query: 80 GRLQVAGRKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138
GRLQV+ RKG PHVIY R+WRWPDL +ELK + C++ F K VC+NPYHY+RV S
Sbjct: 74 GRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVES 133
Query: 139 PGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQ-HPPSNRASTETY-- 195
P + P ++ + ++F Q SL + ++ + H P N +++
Sbjct: 134 PVL-----------PPVLVPRH---NEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQ 179
Query: 196 --STPALLAPSESNATSTANFPNIPVAST--SQPASILGGSHSEGLLQIASGPQPGQQQN 251
+TP L+P+ + +P P +ST + PAS SGP Q
Sbjct: 180 PNNTPFPLSPN-------SPYPPSPASSTYPNSPAS--------------SGPGSPFQLP 218
Query: 252 GFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPG---HYWPVHNEL 308
T PA Y P P Q G + PM P +
Sbjct: 219 ADTPPPA-----------------YMP--PDDQMGQ-DNSQPMDTSNNMIPQIMPSISSR 258
Query: 309 AFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGG-DRFCLGQL 367
QP + P++WCSI Y+E++ +VGE F S+ V VDG+ DPS RFCLG L
Sbjct: 259 DVQPVA--YEEPKHWCSIVYYELNNRVGEAFHASSTS--VLVDGFTDPSNNKSRFCLGLL 314
Query: 368 SNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVH 427
SNV+R IE R HIGKGV L G G+V+ CLSD ++FVQS + G P V
Sbjct: 315 SNVNRNSTIENTRRHIGKGVHLYYVG-GEVYAECLSDSSIFVQSRNCNFHHGFHP-TTVC 372
Query: 428 KIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAA 487
KI S +K+F+ ++ + + Q A
Sbjct: 373 KIPSSCSLKIFNNQEFAQLLAQSVNHGFEA------------------------------ 402
Query: 488 AGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 543
V +L ++C +RMSFVKGWG +Y RQ + TPCWIEIHLH LQ LD+VL M
Sbjct: 403 ----VYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQM 454
>gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]
Length = 465
Score = 267 bits (682), Expect = 2e-71
Identities = 194/536 (36%), Positives = 268/536 (50%), Gaps = 108/536 (20%)
Query: 20 VHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLD 79
V L+ +QG E E +A++A+++LVKKLK+KK ++ L A+++ G PSKCVTI R+LD
Sbjct: 15 VKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG-QPSKCVTIPRSLD 73
Query: 80 GRLQVAGRKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138
GRLQV+ RKG PHVIY R+WRWPDL +ELK + C++ F K VC+NPYHY+RV S
Sbjct: 74 GRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVES 133
Query: 139 PGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQ-HPPSNRASTETY-- 195
P + P ++ + ++F Q SL + ++ + H P N +++
Sbjct: 134 PVL-----------PPVLVPRH---NEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQ 179
Query: 196 --STPALLAPSESNATSTANFPNIPVAST--SQPASILGGSHSEGLLQIASGPQPGQQQN 251
+TP L+P+ + +P P +ST + PAS SGP Q
Sbjct: 180 PNNTPFPLSPN-------SPYPPSPASSTYPNSPAS--------------SGPGSPFQLP 218
Query: 252 GFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPG---HYWPVHNEL 308
T PA Y P P Q G + PM P +
Sbjct: 219 ADTPPPA-----------------YMP--PDDQMGQ-DNSQPMDTSNNMIPQIMPSISSR 258
Query: 309 AFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGG-DRFCLGQL 367
QP + P++WCSI Y+E++ +VGE F S+ V VDG+ DPS RFCLG L
Sbjct: 259 DVQPVA--YEEPKHWCSIVYYELNNRVGEAFHASSTS--VLVDGFTDPSNNKSRFCLGLL 314
Query: 368 SNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVH 427
SNV+R IE R HIGKGV L G G+V+ CLSD ++FVQS + G P V
Sbjct: 315 SNVNRNSTIENTRRHIGKGVHLYYVG-GEVYAECLSDSSIFVQSRNCNFHHGFHP-TTVC 372
Query: 428 KIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAA 487
KI S +K+F+ ++ + + Q A
Sbjct: 373 KIPSSCSLKIFNNQEFAQLLAQSVNHGFEA------------------------------ 402
Query: 488 AGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 543
V +L ++C +RMSFVKGWG +Y RQ + TPCWIEIHLH LQ LD+VL M
Sbjct: 403 ----VYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQM 454
>gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]
Length = 465
Score = 267 bits (682), Expect = 2e-71
Identities = 194/536 (36%), Positives = 268/536 (50%), Gaps = 108/536 (20%)
Query: 20 VHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLD 79
V L+ +QG E E +A++A+++LVKKLK+KK ++ L A+++ G PSKCVTI R+LD
Sbjct: 15 VKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG-QPSKCVTIPRSLD 73
Query: 80 GRLQVAGRKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138
GRLQV+ RKG PHVIY R+WRWPDL +ELK + C++ F K VC+NPYHY+RV S
Sbjct: 74 GRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVES 133
Query: 139 PGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQ-HPPSNRASTETY-- 195
P + P ++ + ++F Q SL + ++ + H P N +++
Sbjct: 134 PVL-----------PPVLVPRH---NEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQ 179
Query: 196 --STPALLAPSESNATSTANFPNIPVAST--SQPASILGGSHSEGLLQIASGPQPGQQQN 251
+TP L+P+ + +P P +ST + PAS SGP Q
Sbjct: 180 PNNTPFPLSPN-------SPYPPSPASSTYPNSPAS--------------SGPGSPFQLP 218
Query: 252 GFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPG---HYWPVHNEL 308
T PA Y P P Q G + PM P +
Sbjct: 219 ADTPPPA-----------------YMP--PDDQMGQ-DNSQPMDTSNNMIPQIMPSISSR 258
Query: 309 AFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGG-DRFCLGQL 367
QP + P++WCSI Y+E++ +VGE F S+ V VDG+ DPS RFCLG L
Sbjct: 259 DVQPVA--YEEPKHWCSIVYYELNNRVGEAFHASSTS--VLVDGFTDPSNNKSRFCLGLL 314
Query: 368 SNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVH 427
SNV+R IE R HIGKGV L G G+V+ CLSD ++FVQS + G P V
Sbjct: 315 SNVNRNSTIENTRRHIGKGVHLYYVG-GEVYAECLSDSSIFVQSRNCNFHHGFHP-TTVC 372
Query: 428 KIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAA 487
KI S +K+F+ ++ + + Q A
Sbjct: 373 KIPSSCSLKIFNNQEFAQLLAQSVNHGFEA------------------------------ 402
Query: 488 AGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 543
V +L ++C +RMSFVKGWG +Y RQ + TPCWIEIHLH LQ LD+VL M
Sbjct: 403 ----VYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQM 454
>gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]
Length = 465
Score = 265 bits (677), Expect = 8e-71
Identities = 190/530 (35%), Positives = 265/530 (50%), Gaps = 95/530 (17%)
Query: 20 VHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLD 79
V L+ +QG E E +A++A+++LVKKLK+KK ++ L A++ G PS CVTI R+LD
Sbjct: 14 VKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG-QPSNCVTIPRSLD 72
Query: 80 GRLQVAGRKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138
GRLQV+ RKG PHVIY R+WRWPDL +ELK ++ C++ F K VC+NPYHY+RV S
Sbjct: 73 GRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYKRVES 132
Query: 139 PGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSI-QTIQHPPSNRASTETYST 197
P + P ++ + ++ Q SL + ++ Q H P N +++
Sbjct: 133 PVL-----------PPVLVPRHS---EYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQ 178
Query: 198 PALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGLLQIASGPQPGQQQNGFTGQP 257
P ++ FP+ P ++S P S S + +S P Q T P
Sbjct: 179 P-----------NSHPFPHSP--NSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPP 225
Query: 258 ATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPP--HPGHYWPVHNELAFQPPIS 315
A T GS+ P N+ PP+P + G V E
Sbjct: 226 AYLPPEDPMTQDGSQ--PMDTNM---------MAPPLPSEINRGDVQAVAYE-------- 266
Query: 316 NHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGG-DRFCLGQLSNVHRTE 374
P++WCSI Y+E++ +VGE F S+ V VDG+ DPS +RFCLG LSNV+R
Sbjct: 267 ---EPKHWCSIVYYELNNRVGEAFHASSTS--VLVDGFTDPSNNKNRFCLGLLSNVNRNS 321
Query: 375 AIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAY 434
IE R HIGKGV L G G+V+ CLSD ++FVQS + G P V KI
Sbjct: 322 TIENTRRHIGKGVHLYYVG-GEVYAECLSDSSIFVQSRNCNYHHGFHP-TTVCKIPSGCS 379
Query: 435 IKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGI-GVD 493
+K+F+ ++ A ++ S G V
Sbjct: 380 LKIFNNQE-----------------------------------FAQLLAQSVNHGFETVY 404
Query: 494 DLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 543
+L ++C +RMSFVKGWG +Y RQ + TPCWIEIHLH LQ LD+VL M
Sbjct: 405 ELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQM 454
>gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]
Length = 465
Score = 265 bits (677), Expect = 8e-71
Identities = 190/530 (35%), Positives = 265/530 (50%), Gaps = 95/530 (17%)
Query: 20 VHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLD 79
V L+ +QG E E +A++A+++LVKKLK+KK ++ L A++ G PS CVTI R+LD
Sbjct: 14 VKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG-QPSNCVTIPRSLD 72
Query: 80 GRLQVAGRKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138
GRLQV+ RKG PHVIY R+WRWPDL +ELK ++ C++ F K VC+NPYHY+RV S
Sbjct: 73 GRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYKRVES 132
Query: 139 PGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSI-QTIQHPPSNRASTETYST 197
P + P ++ + ++ Q SL + ++ Q H P N +++
Sbjct: 133 PVL-----------PPVLVPRHS---EYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQ 178
Query: 198 PALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGLLQIASGPQPGQQQNGFTGQP 257
P ++ FP+ P ++S P S S + +S P Q T P
Sbjct: 179 P-----------NSHPFPHSP--NSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPP 225
Query: 258 ATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPP--HPGHYWPVHNELAFQPPIS 315
A T GS+ P N+ PP+P + G V E
Sbjct: 226 AYLPPEDPMTQDGSQ--PMDTNM---------MAPPLPSEINRGDVQAVAYE-------- 266
Query: 316 NHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGG-DRFCLGQLSNVHRTE 374
P++WCSI Y+E++ +VGE F S+ V VDG+ DPS +RFCLG LSNV+R
Sbjct: 267 ---EPKHWCSIVYYELNNRVGEAFHASSTS--VLVDGFTDPSNNKNRFCLGLLSNVNRNS 321
Query: 375 AIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAY 434
IE R HIGKGV L G G+V+ CLSD ++FVQS + G P V KI
Sbjct: 322 TIENTRRHIGKGVHLYYVG-GEVYAECLSDSSIFVQSRNCNYHHGFHP-TTVCKIPSGCS 379
Query: 435 IKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGI-GVD 493
+K+F+ ++ A ++ S G V
Sbjct: 380 LKIFNNQE-----------------------------------FAQLLAQSVNHGFETVY 404
Query: 494 DLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 543
+L ++C +RMSFVKGWG +Y RQ + TPCWIEIHLH LQ LD+VL M
Sbjct: 405 ELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQM 454
>gi|5174519 SMAD family member 9 isoform b [Homo sapiens]
Length = 430
Score = 236 bits (601), Expect = 5e-62
Identities = 179/526 (34%), Positives = 242/526 (46%), Gaps = 126/526 (23%)
Query: 20 VHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLD 79
V L+ +QG E E +A++A++SLVKKLK+KK +D L A++ G PSKCVTI R+LD
Sbjct: 18 VKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPG-QPSKCVTIPRSLD 76
Query: 80 GRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVSP 139
GRLQV+ RKG PHVIY R+WRWPDL + +LK C P+
Sbjct: 77 GRLQVSHRKGLPHVIYCRVWRWPDLQSHH-----------ELKPLECCEFPF-------- 117
Query: 140 GIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQHPPSNRASTETYSTPA 199
G + + P + ET P
Sbjct: 118 ------------------------------------GSKQKEVCINPYHYRRVETPVLPP 141
Query: 200 LLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGLL-QIASGPQPGQQQNGFTGQPA 258
+L P S P + + + + AS+ HSE L+ A+ P QQ P+
Sbjct: 142 VLVPRHSEYN-----PQLSLLAKFRSASL----HSEPLMPHNATYPDSFQQPPCSALPPS 192
Query: 259 TYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGHYWPVHNELAFQPPISNHP 318
H S + T S P++P P QH F+P +
Sbjct: 193 PSHAFSQSPCTASY--PHSPGSPSEPESPYQHSD-----------------FRPVC--YE 231
Query: 319 APEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGG-DRFCLGQLSNVHRTEAIE 377
P++WCS+AY+E++ +VGETF+ S V +DG+ DPS +RFCLG LSNV+R IE
Sbjct: 232 EPQHWCSVAYYELNNRVGETFQASSRS--VLIDGFTDPSNNRNRFCLGLLSNVNRNSTIE 289
Query: 378 RARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKV 437
R HIGKGV L G G+V+ C+SD ++FVQS + + G P V KI +KV
Sbjct: 290 NTRRHIGKGVHLYYVG-GEVYAECVSDSSIFVQSRNCNYQHGFHPA-TVCKIPSGCSLKV 347
Query: 438 FDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGIGVDDLRR 497
F+ Q A A + V V +L +
Sbjct: 348 FN--------NQLFAQLLAQSVHHGFEV--------------------------VYELTK 373
Query: 498 LCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 543
+C +RMSFVKGWG +Y RQ + TPCWIEIHLH LQ LD+VL M
Sbjct: 374 MCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQM 419
>gi|223029442 mothers against decapentaplegic homolog 3 isoform 3
[Homo sapiens]
Length = 381
Score = 205 bits (521), Expect = 1e-52
Identities = 158/471 (33%), Positives = 209/471 (44%), Gaps = 128/471 (27%)
Query: 76 RTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYER 135
R+LDGRLQV+ RKG PHVIY RLWRWPDLH + +L+ +C ++
Sbjct: 25 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHH-----------ELRAMELCEFAFN--- 70
Query: 136 VVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQHPPSNRASTETY 195
M KDE + P + ET
Sbjct: 71 ---------------------MKKDEVCVN--------------------PYHYQRVETP 89
Query: 196 STPALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGLLQIASGPQPGQ-QQNGFT 254
P +L P + A FP + S S P + + E I P PG ++G T
Sbjct: 90 VLPPVLVPRHTEIP--AEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGET 147
Query: 255 GQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQH--HPPMPPHPGHYWPVHNELAFQP 312
HQ H P + P+P P HN L QP
Sbjct: 148 SD--------------------------HQMNHSMDAGSPNLSPNPMS--PAHNNLDLQP 179
Query: 313 PISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHR 372
PA +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RFCLG LSNV+R
Sbjct: 180 VTYCEPA--FWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERFCLGLLSNVNR 235
Query: 373 TEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPS 432
A+E R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P V KI P
Sbjct: 236 NAAVELTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHPA-TVCKIPPG 293
Query: 433 AYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGIGV 492
+K+F+ Q+ A A + Q V
Sbjct: 294 CNLKIFN--------NQEFAALLAQSVNQGFE--------------------------AV 319
Query: 493 DDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 543
L R+C +RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL M
Sbjct: 320 YQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM 370
>gi|223029440 mothers against decapentaplegic homolog 3 isoform 2
[Homo sapiens]
Length = 320
Score = 180 bits (456), Expect = 3e-45
Identities = 139/433 (32%), Positives = 189/433 (43%), Gaps = 125/433 (28%)
Query: 112 VKYCQYAFDLKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPS 171
++ C++AF++K D VCVNPYHY+RV +P + + + P+ D+Y H
Sbjct: 1 MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSI----- 55
Query: 172 LSTEGHSIQTIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASILGG 231
P N T+ PA I
Sbjct: 56 --------------PEN---------------------------------TNFPAGI--- 65
Query: 232 SHSEGLLQIASGPQPGQ-QQNGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQH 290
E I P PG ++G T H + + GS P P H N LQ
Sbjct: 66 ---EPQSNIPETPPPGYLSEDGETSD----HQMNHSMDAGSPNLSPNPMSPAHNNLDLQ- 117
Query: 291 HPPMPPHPGHYWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTV 350
P PA +WCSI+Y+E++ +VGETF +S P +TV
Sbjct: 118 ---------------------PVTYCEPA--FWCSISYYELNQRVGETFH--ASQPSMTV 152
Query: 351 DGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQ 410
DG+ DPS +RFCLG LSNV+R A+E R HIG+GV+L G G+V+ CLSD A+FVQ
Sbjct: 153 DGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQ 211
Query: 411 SYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIP 470
S ++ G P V KI P +K+F+ Q+ A A + Q
Sbjct: 212 SPNCNQRYGWHPA-TVCKIPPGCNLKIFN--------NQEFAALLAQSVNQGFE------ 256
Query: 471 GPGSVGGIAPAISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLH 530
V L R+C +RMSFVKGWG +Y RQ++ TPCWIE+HL+
Sbjct: 257 --------------------AVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLN 296
Query: 531 RALQLLDEVLHTM 543
LQ LD+VL M
Sbjct: 297 GPLQWLDKVLTQM 309
>gi|223029444 mothers against decapentaplegic homolog 3 isoform 4
[Homo sapiens]
Length = 230
Score = 171 bits (434), Expect = 1e-42
Identities = 105/252 (41%), Positives = 139/252 (55%), Gaps = 42/252 (16%)
Query: 292 PPMPPHPGHYWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVD 351
P + P+P P HN L QP PA +WCSI+Y+E++ +VGETF +S P +TVD
Sbjct: 10 PNLSPNPMS--PAHNNLDLQPVTYCEPA--FWCSISYYELNQRVGETFH--ASQPSMTVD 63
Query: 352 GYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQS 411
G+ DPS +RFCLG LSNV+R A+E R HIG+GV+L G G+V+ CLSD A+FVQS
Sbjct: 64 GFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQS 122
Query: 412 YYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPG 471
++ G P V KI P +K+F+ Q+ A A + Q
Sbjct: 123 PNCNQRYGWHPA-TVCKIPPGCNLKIFN--------NQEFAALLAQSVNQGFE------- 166
Query: 472 PGSVGGIAPAISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHR 531
V L R+C +RMSFVKGWG +Y RQ++ TPCWIE+HL+
Sbjct: 167 -------------------AVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNG 207
Query: 532 ALQLLDEVLHTM 543
LQ LD+VL M
Sbjct: 208 PLQWLDKVLTQM 219
>gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
Length = 467
Score = 168 bits (426), Expect = 1e-41
Identities = 101/241 (41%), Positives = 135/241 (56%), Gaps = 40/241 (16%)
Query: 303 PVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRF 362
PV++ L QP + PA +WCSIAY+E++ +VGETF +S P +TVDG+ DPS +RF
Sbjct: 256 PVNHSLDLQPVTYSEPA--FWCSIAYYELNQRVGETFH--ASQPSLTVDGFTDPSNSERF 311
Query: 363 CLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAP 422
CLG LSNV+R +E R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P
Sbjct: 312 CLGLLSNVNRNATVEMTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHP 370
Query: 423 GDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAI 482
V KI P +K+F+ Q+ A A + Q
Sbjct: 371 A-TVCKIPPGCNLKIFN--------NQEFAALLAQSVNQGFE------------------ 403
Query: 483 SLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHT 542
V L R+C +RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL
Sbjct: 404 --------AVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQ 455
Query: 543 M 543
M
Sbjct: 456 M 456
Score = 126 bits (317), Expect = 5e-29
Identities = 73/168 (43%), Positives = 96/168 (57%), Gaps = 33/168 (19%)
Query: 28 QGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQ------------ 75
Q G+ E + ++A++SLVKKLK K LD L AITT + +KCVTI
Sbjct: 33 QNGQEEKWCEKAVKSLVKKLK-KTGRLDELEKAITTQNCN-TKCVTIPSTCSEIWGLSTP 90
Query: 76 ------------------RTLDGRLQVAGRKGFPHVIYARLWRWPDLHK-NELKHVKYCQ 116
R+LDGRLQV+ RKG PHVIY RLWRWPDLH +ELK ++ C+
Sbjct: 91 NTIDQWDTTGLYSFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCE 150
Query: 117 YAFDLKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPSSMMVKDEYVH 164
YAF+LK D VCVNPYHY+RV +P + + + + + D+Y H
Sbjct: 151 YAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTH 198
>gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
Length = 467
Score = 168 bits (426), Expect = 1e-41
Identities = 101/241 (41%), Positives = 135/241 (56%), Gaps = 40/241 (16%)
Query: 303 PVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRF 362
PV++ L QP + PA +WCSIAY+E++ +VGETF +S P +TVDG+ DPS +RF
Sbjct: 256 PVNHSLDLQPVTYSEPA--FWCSIAYYELNQRVGETFH--ASQPSLTVDGFTDPSNSERF 311
Query: 363 CLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAP 422
CLG LSNV+R +E R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P
Sbjct: 312 CLGLLSNVNRNATVEMTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHP 370
Query: 423 GDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAI 482
V KI P +K+F+ Q+ A A + Q
Sbjct: 371 A-TVCKIPPGCNLKIFN--------NQEFAALLAQSVNQGFE------------------ 403
Query: 483 SLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHT 542
V L R+C +RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL
Sbjct: 404 --------AVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQ 455
Query: 543 M 543
M
Sbjct: 456 M 456
Score = 126 bits (317), Expect = 5e-29
Identities = 73/168 (43%), Positives = 96/168 (57%), Gaps = 33/168 (19%)
Query: 28 QGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQ------------ 75
Q G+ E + ++A++SLVKKLK K LD L AITT + +KCVTI
Sbjct: 33 QNGQEEKWCEKAVKSLVKKLK-KTGRLDELEKAITTQNCN-TKCVTIPSTCSEIWGLSTP 90
Query: 76 ------------------RTLDGRLQVAGRKGFPHVIYARLWRWPDLHK-NELKHVKYCQ 116
R+LDGRLQV+ RKG PHVIY RLWRWPDLH +ELK ++ C+
Sbjct: 91 NTIDQWDTTGLYSFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCE 150
Query: 117 YAFDLKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPSSMMVKDEYVH 164
YAF+LK D VCVNPYHY+RV +P + + + + + D+Y H
Sbjct: 151 YAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTH 198
>gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo
sapiens]
Length = 437
Score = 168 bits (426), Expect = 1e-41
Identities = 101/241 (41%), Positives = 135/241 (56%), Gaps = 40/241 (16%)
Query: 303 PVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRF 362
PV++ L QP + PA +WCSIAY+E++ +VGETF +S P +TVDG+ DPS +RF
Sbjct: 226 PVNHSLDLQPVTYSEPA--FWCSIAYYELNQRVGETFH--ASQPSLTVDGFTDPSNSERF 281
Query: 363 CLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAP 422
CLG LSNV+R +E R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P
Sbjct: 282 CLGLLSNVNRNATVEMTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHP 340
Query: 423 GDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAI 482
V KI P +K+F+ Q+ A A + Q
Sbjct: 341 A-TVCKIPPGCNLKIFN--------NQEFAALLAQSVNQGFE------------------ 373
Query: 483 SLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHT 542
V L R+C +RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL
Sbjct: 374 --------AVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQ 425
Query: 543 M 543
M
Sbjct: 426 M 426
Score = 142 bits (358), Expect = 8e-34
Identities = 73/138 (52%), Positives = 96/138 (69%), Gaps = 3/138 (2%)
Query: 28 QGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGR 87
Q G+ E + ++A++SLVKKLK K LD L AITT + +KCVTI R+LDGRLQV+ R
Sbjct: 33 QNGQEEKWCEKAVKSLVKKLK-KTGRLDELEKAITTQNCN-TKCVTIPRSLDGRLQVSHR 90
Query: 88 KGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERVVSPGIDLSGL 146
KG PHVIY RLWRWPDLH +ELK ++ C+YAF+LK D VCVNPYHY+RV +P + +
Sbjct: 91 KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV 150
Query: 147 TLQSNAPSSMMVKDEYVH 164
+ + + D+Y H
Sbjct: 151 PRHTEILTELPPLDDYTH 168
>gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]
Length = 235
Score = 99.0 bits (245), Expect = 1e-20
Identities = 70/211 (33%), Positives = 93/211 (44%), Gaps = 45/211 (21%)
Query: 320 PEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERA 379
P +WCS+AY+E +VG + V V + D G FCLGQL+ R+E++ R
Sbjct: 67 PSHWCSVAYWEHRTRVGRLYAVYDQA----VSIFYDLPQGSGFCLGQLNLEQRSESVRRT 122
Query: 380 RLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFD 439
R IG G+ L + +G VW +H +FV S LD GRA V K+ P IKVFD
Sbjct: 123 RSKIGFGILLSKEPDG-VWAYNRGEHPIFVNSPTLDAPGGRAL--VVRKVPPGYSIKVFD 179
Query: 440 LRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGIGVDDLRRLC 499
+ Q + P P + G S
Sbjct: 180 FERSGLQ---------------------HAPEPDAADGPYDPNS---------------- 202
Query: 500 ILRMSFVKGWGPDYPRQSIKETPCWIEIHLH 530
+R+SF KGWGP Y RQ I PCW+EI L+
Sbjct: 203 -VRISFAKGWGPCYSRQFITSCPCWLEILLN 232
>gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]
Length = 496
Score = 99.0 bits (245), Expect = 1e-20
Identities = 70/211 (33%), Positives = 93/211 (44%), Gaps = 45/211 (21%)
Query: 320 PEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERA 379
P +WCS+AY+E +VG + V V + D G FCLGQL+ R+E++ R
Sbjct: 328 PSHWCSVAYWEHRTRVGRLYAVYDQA----VSIFYDLPQGSGFCLGQLNLEQRSESVRRT 383
Query: 380 RLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFD 439
R IG G+ L + +G VW +H +FV S LD GRA V K+ P IKVFD
Sbjct: 384 RSKIGFGILLSKEPDG-VWAYNRGEHPIFVNSPTLDAPGGRAL--VVRKVPPGYSIKVFD 440
Query: 440 LRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGIGVDDLRRLC 499
+ Q + P P + G S
Sbjct: 441 FERSGLQ---------------------HAPEPDAADGPYDPNS---------------- 463
Query: 500 ILRMSFVKGWGPDYPRQSIKETPCWIEIHLH 530
+R+SF KGWGP Y RQ I PCW+EI L+
Sbjct: 464 -VRISFAKGWGPCYSRQFITSCPCWLEILLN 493
Score = 67.8 bits (164), Expect = 2e-11
Identities = 41/106 (38%), Positives = 61/106 (57%), Gaps = 9/106 (8%)
Query: 37 KRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYA 96
K SL+K+LKE+ LD+L+ A+ + G P CV + R L++ G+ P ++
Sbjct: 173 KTVTYSLLKRLKERS--LDTLLEAVESRGGVPGGCVLVPRA---DLRLGGQPAPPQLLLG 227
Query: 97 RLWRWPDL-HKNELKHVKYCQYAFDLKCD--SVCVNPYHYERVVSP 139
RL+RWPDL H ELK + C ++F D +VC NPYH+ R+ P
Sbjct: 228 RLFRWPDLQHAVELKPLCGC-HSFAAAADGPTVCCNPYHFSRLCGP 272
>gi|5174517 SMAD family member 7 [Homo sapiens]
Length = 426
Score = 87.8 bits (216), Expect = 2e-17
Identities = 62/214 (28%), Positives = 95/214 (44%), Gaps = 60/214 (28%)
Query: 322 YWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARL 381
+WC +AY+E +VG + V ++D + D G+ FCLGQL++ ++++ +++ R
Sbjct: 260 HWCVVAYWEEKTRVGRLYCVQEP----SLDIFYDLPQGNGFCLGQLNSDNKSQLVQKVRS 315
Query: 382 HIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLR 441
IG G+QL + +G VWV S + +F++S LD R VHK++P IK FD
Sbjct: 316 KIGCGIQLTREVDG-VWVYNRSSYPIFIKSATLDNPDSRTL--LVHKVFPGFSIKAFDYE 372
Query: 442 QC--------HRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGIGVD 493
+ H MQQ P G
Sbjct: 373 KAYSLQRPNDHEFMQQ--------------------PWTGFT------------------ 394
Query: 494 DLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEI 527
+++SFVKGWG Y RQ I PCW+E+
Sbjct: 395 -------VQISFVKGWGQCYTRQFISSCPCWLEV 421
Score = 53.9 bits (128), Expect = 4e-07
Identities = 35/118 (29%), Positives = 59/118 (50%), Gaps = 13/118 (11%)
Query: 30 GESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKG 89
G +E K S++KKLKE++ EL L+ A+ + G + C+ + LD RL G
Sbjct: 86 GGAEADLKALTHSVLKKLKERQLEL--LLQAVESRGGTRTACLLLPGRLDCRLGPGAPAG 143
Query: 90 FPH----------VIYARLWRWPDL-HKNELKHVKYCQYAFDLKCDSVCVNPYHYERV 136
++ +++RWPDL H +E+K + C+ + + VC NP+H R+
Sbjct: 144 AQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRL 201
>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
Length = 500
Score = 42.7 bits (99), Expect = 9e-04
Identities = 32/120 (26%), Positives = 47/120 (39%), Gaps = 13/120 (10%)
Query: 185 PPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASIL----GGSHSEGLLQI 240
PP ++ + A A + + A + A+ P++ P S+L GG G+L
Sbjct: 177 PPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGML-- 234
Query: 241 ASGPQPGQQQNGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGH 300
++ P PG G G + H TP L H + H H P PPHP H
Sbjct: 235 SAPPGPGGGGGGAGGGAQSLVHPGLVRGD-------TPELAEHHHHHHHHAHPHPPHPHH 287
>gi|153792780 additional sex combs like 2 [Homo sapiens]
Length = 1435
Score = 42.0 bits (97), Expect = 0.001
Identities = 21/32 (65%), Positives = 23/32 (71%)
Query: 449 QQAATAQAAAAAQAAAVAGNIPGPGSVGGIAP 480
Q+AA A AAAAA AA+V G IPGPG GG P
Sbjct: 670 QRAAAAAAAAAAAAASVGGTIPGPGPGGGQGP 701
>gi|50345831 forkhead box J3 [Homo sapiens]
Length = 622
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/121 (24%), Positives = 49/121 (40%), Gaps = 14/121 (11%)
Query: 173 STEGHSIQTIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASILGGS 232
S + H+ T QH PS+ ST +S + L+ S + +T ++ S S P
Sbjct: 321 SQQSHTSCTYQHSPSSTVSTHPHSNQSSLSNSHGSGLNTTGSNSVAQVSLSHPQ------ 374
Query: 233 HSEGLLQIASGPQPGQQQNGFTGQPATYHHNSTTTWTGSR-TAPYTPNLPHHQNGHLQHH 291
+ P P + +G P H + S+ +P+ + HQ H+QHH
Sbjct: 375 -----MHTQPSPHPPHRPHGLPQHPQRSPHPAPHPQQHSQLQSPHPQHPSPHQ--HIQHH 427
Query: 292 P 292
P
Sbjct: 428 P 428
>gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]
Length = 1597
Score = 38.5 bits (88), Expect = 0.016
Identities = 37/141 (26%), Positives = 56/141 (39%), Gaps = 18/141 (12%)
Query: 185 PPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASILGGSHS--EGLLQIAS 242
PP R T P+++ E++ + P + S P ++ G H+ +G L AS
Sbjct: 728 PPPQRRDTH----PSVV---ETDGHARVVVPTLKQHSHPPPLALGSGLHAPHKGPLPQAS 780
Query: 243 GPQPGQQQNGFTGQPATYHH-NSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPM--PPHPG 299
P +Q P + HH +T W ++ P TP+LP H PP+ P
Sbjct: 781 DPAVARQHRPLPSTPDSSHHAQATPRWRYNKPLPPTPDLPQ------PHLPPISAPGSSR 834
Query: 300 HYWPVHNELAFQPPISNHPAP 320
Y P+ PP P P
Sbjct: 835 IYRPLPPLPIIDPPTEPPPLP 855
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 37.0 bits (84), Expect = 0.047
Identities = 45/180 (25%), Positives = 68/180 (37%), Gaps = 29/180 (16%)
Query: 147 TLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQHPPSNRASTETYSTPALLAPSES 206
T Q ++P M K QP T +S Q Q PPS Y P +
Sbjct: 377 TPQPSSPMDQMGK------MRPQPYGGTNPYSQQ--QGPPSGPQQGHGY-------PGQP 421
Query: 207 NATSTANFPNIPVASTSQPASILGG-SHSEGLLQIASGPQPGQQ-QNGFTGQPATYHHNS 264
+ T P+ + S +GG S+++ + P GQQ +G+ Q T ++N
Sbjct: 422 YGSQTPQ--RYPMTMQGRAQSAMGGLSYTQQI------PPYGQQGPSGYGQQGQTPYYNQ 473
Query: 265 TTTWTGSRTAPYTPN----LPHHQNGHLQHHPPMPPHPGHYWPVHNELAFQPPISNHPAP 320
+ + PY+ PH Q + Q PP P +++ QPP PAP
Sbjct: 474 QSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAP 533
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 37.0 bits (84), Expect = 0.047
Identities = 45/180 (25%), Positives = 68/180 (37%), Gaps = 29/180 (16%)
Query: 147 TLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQHPPSNRASTETYSTPALLAPSES 206
T Q ++P M K QP T +S Q Q PPS Y P +
Sbjct: 377 TPQPSSPMDQMGK------MRPQPYGGTNPYSQQ--QGPPSGPQQGHGY-------PGQP 421
Query: 207 NATSTANFPNIPVASTSQPASILGG-SHSEGLLQIASGPQPGQQ-QNGFTGQPATYHHNS 264
+ T P+ + S +GG S+++ + P GQQ +G+ Q T ++N
Sbjct: 422 YGSQTPQ--RYPMTMQGRAQSAMGGLSYTQQI------PPYGQQGPSGYGQQGQTPYYNQ 473
Query: 265 TTTWTGSRTAPYTPN----LPHHQNGHLQHHPPMPPHPGHYWPVHNELAFQPPISNHPAP 320
+ + PY+ PH Q + Q PP P +++ QPP PAP
Sbjct: 474 QSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAP 533
>gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens]
Length = 1321
Score = 36.6 bits (83), Expect = 0.062
Identities = 31/106 (29%), Positives = 39/106 (36%), Gaps = 14/106 (13%)
Query: 175 EGHSIQTIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVA-----STSQPASIL 229
E H T PPS A T+ YS P L P+ + P P A + PA +
Sbjct: 658 EAHGEATATAPPSPAAETKVYSLPLSLTPTGQGGEAMPTTPESPRADFRETGETSPAQVN 717
Query: 230 GGSHSEGLLQIASGPQPGQQQNGFTGQPATYHHNSTTTWTGSRTAP 275
HS +S P P +N G T + T TG R P
Sbjct: 718 KAEHS------SSSPWPSVNRNVAVGFVPT---ETATEPTGLRGIP 754
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 35.8 bits (81), Expect = 0.10
Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 4/44 (9%)
Query: 275 PYTPNLPHHQNGHLQHHPPMPPHPGHYWPVHNELAFQPPISNHP 318
P P+LP H HL HP +P HP + P H L P + HP
Sbjct: 10 PTHPHLPTHP--HLPTHPHLPTHP--HLPTHPHLPTHPHLPTHP 49
Score = 30.4 bits (67), Expect = 4.4
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 2/32 (6%)
Query: 287 HLQHHPPMPPHPGHYWPVHNELAFQPPISNHP 318
HL HP +P HP + P H L P + HP
Sbjct: 8 HLPTHPHLPTHP--HLPTHPHLPTHPHLPTHP 37
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 35.8 bits (81), Expect = 0.10
Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 4/44 (9%)
Query: 275 PYTPNLPHHQNGHLQHHPPMPPHPGHYWPVHNELAFQPPISNHP 318
P P+LP H HL HP +P HP + P H L P + HP
Sbjct: 10 PTHPHLPTHP--HLPTHPHLPTHP--HLPTHPHLPTHPHLPTHP 49
Score = 30.4 bits (67), Expect = 4.4
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 2/32 (6%)
Query: 287 HLQHHPPMPPHPGHYWPVHNELAFQPPISNHP 318
HL HP +P HP + P H L P + HP
Sbjct: 8 HLPTHPHLPTHP--HLPTHPHLPTHPHLPTHP 37
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 35.8 bits (81), Expect = 0.10
Identities = 44/186 (23%), Positives = 67/186 (36%), Gaps = 18/186 (9%)
Query: 133 YERVVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQHPPSNRAST 192
Y +P S T S PS+ V H P+ S ++ T H P S
Sbjct: 1397 YTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPT--HVPPFSTSL 1454
Query: 193 ETYSTPALLAPSESNATSTANFPNIPVASTSQPASI--LGGSHS--------EGLLQIAS 242
T ST ++ P+ + ++A+ + P + P ++ G +H+ G Q S
Sbjct: 1455 VTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHS 1514
Query: 243 GPQPGQQQNGFTGQPATYHH-----NSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPH 297
+ ++ HH STTT T + T+ T H N PP PP
Sbjct: 1515 SFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPP-PPF 1573
Query: 298 PGHYWP 303
H P
Sbjct: 1574 TTHSPP 1579
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 35.8 bits (81), Expect = 0.10
Identities = 36/135 (26%), Positives = 47/135 (34%), Gaps = 23/135 (17%)
Query: 171 SLSTEGHSIQTIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASILG 230
SLS G + I PP+ YSTP + + S S P P + PAS
Sbjct: 911 SLSVPGS--EDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPA 968
Query: 231 GSHSEGLLQIASGPQPGQQQNGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQH 290
GP P + G + + + YH + P P H + H H
Sbjct: 969 SF---------DGPSPPDTRVG-SREKSLYH-----------SGPLPPAHHHPPHHHHHH 1007
Query: 291 HPPMPPHPGHYWPVH 305
PP PH H P H
Sbjct: 1008 APPPQPHHHHAHPPH 1022
>gi|34452686 ring finger protein, LIM domain interacting [Homo
sapiens]
Length = 624
Score = 35.4 bits (80), Expect = 0.14
Identities = 24/112 (21%), Positives = 50/112 (44%), Gaps = 6/112 (5%)
Query: 165 DFEGQPSLSTEGHSIQTIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQ 224
D + +P+ S +++ + S S+ + + S S+++S+++ +S+S
Sbjct: 423 DSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSS------SSSSS 476
Query: 225 PASILGGSHSEGLLQIASGPQPGQQQNGFTGQPATYHHNSTTTWTGSRTAPY 276
P+S GG SE + G G +G +G H + T+ S + P+
Sbjct: 477 PSSSSGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTFDESGSLPF 528
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,987,215
Number of Sequences: 37866
Number of extensions: 1293205
Number of successful extensions: 6238
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 177
Number of HSP's that attempted gapping in prelim test: 5410
Number of HSP's gapped (non-prelim): 813
length of query: 552
length of database: 18,247,518
effective HSP length: 107
effective length of query: 445
effective length of database: 14,195,856
effective search space: 6317155920
effective search space used: 6317155920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.