Guide to the Human Genome
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Name: SMAD3 Sequence: fasta or formatted (230aa) NCBI GI: 223029444
Description:

mothers against decapentaplegic homolog 3 isoform 4

Referenced in:

Myc and Related Functions
TGF-beta Family

Other entries for this name:
alt prot [320aa] mothers against decapentaplegic homolog 3 isoform 2
alt prot [381aa] mothers against decapentaplegic homolog 3 isoform 3
alt prot [425aa] mothers against decapentaplegic homolog 3 isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.1         14           2
 C cysteine            4.3         10           1
 D aspartate           2.6          6           1
 E glutamate           4.8         11           1
 F phenylalanine       4.3         10           1
 G glycine             6.5         15           2
 H histidine           2.6          6           1
 I isoleucine          3.9          9           1
 K lysine              1.7          4           1
 L leucine             8.3         19           2
 M methionine          3.0          7           1
 N asparagine          7.4         17           2
 P proline             6.5         15           2
 Q glutamine           5.2         12           1
 R arginine            5.7         13           2
 S serine              9.6         22           2
 T threonine           5.2         12           1
 V valine              6.5         15           1
 W tryptophan          2.2          5           1
 Y tyrosine            3.5          8           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mothers against decapentaplegic homolog 3 isoform 4... 
SMAD3                 1.000   mothers against decapentaplegic homolog 3 isoform 1 [...
SMAD3                 1.000   mothers against decapentaplegic homolog 3 isoform 3...
SMAD3                 1.000   mothers against decapentaplegic homolog 3 isoform 2...
SMAD2                 0.918   Sma- and Mad-related protein 2 isoform 1 
SMAD2                 0.918   Sma- and Mad-related protein 2 isoform 1 
SMAD2                 0.918   Sma- and Mad-related protein 2 isoform 2 
SMAD5                 0.693   SMAD, mothers against DPP homolog 5 
SMAD5                 0.693   SMAD, mothers against DPP homolog 5 
SMAD5                 0.693   SMAD, mothers against DPP homolog 5 
SMAD1                 0.688   Sma- and Mad-related protein 1 
SMAD1                 0.688   Sma- and Mad-related protein 1 
SMAD9                 0.680   SMAD family member 9 isoform b 
SMAD9                 0.671   SMAD family member 9 isoform a 
SMAD4                 0.316   mothers against decapentaplegic homolog 4 
SMAD6                 0.162   SMAD family member 6 isoform 2 
SMAD6                 0.162   SMAD family member 6 isoform 1 
SMAD7                 0.139   SMAD family member 7 
ITGAX                 0.013   integrin alpha X precursor 
MAD2L1BP              0.006   MAD2L1 binding protein isoform 1 
DCDC5                 0.006   PREDICTED: doublecortin domain containing 5 
DCDC5                 0.006   PREDICTED: doublecortin domain containing 5 
DCDC5                 0.006   PREDICTED: doublecortin domain containing 5 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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