Guide to the Human Genome
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Name: SMAD6 Sequence: fasta or formatted (235aa) NCBI GI: 218749837
Description:

SMAD family member 6 isoform 2

Referenced in:

TGF-beta Family

Other entries for this name:
alt prot [496aa] SMAD family member 6 isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.0         14           2
 C cysteine            2.1          5           1
 D aspartate           5.5         13           1
 E glutamate           5.5         13           1
 F phenylalanine       3.8          9           1
 G glycine             7.2         17           2
 H histidine           1.7          4           1
 I isoleucine          4.3         10           1
 K lysine              3.8          9           1
 L leucine             7.7         18           2
 M methionine          1.3          3           1
 N asparagine          3.0          7           2
 P proline            10.2         24           4
 Q glutamine           3.0          7           1
 R arginine            7.2         17           2
 S serine             11.1         26           1
 T threonine           4.7         11           1
 V valine              5.1         12           2
 W tryptophan          2.1          5           1
 Y tyrosine            4.7         11           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SMAD family member 6 isoform 2 
SMAD6                 0.951   SMAD family member 6 isoform 1 
SMAD7                 0.473   SMAD family member 7 
SMAD2                 0.171   Sma- and Mad-related protein 2 isoform 1 
SMAD2                 0.171   Sma- and Mad-related protein 2 isoform 1 
SMAD2                 0.171   Sma- and Mad-related protein 2 isoform 2 
SMAD3                 0.162   mothers against decapentaplegic homolog 3 isoform 1 [...
SMAD3                 0.162   mothers against decapentaplegic homolog 3 isoform 3...
SMAD3                 0.162   mothers against decapentaplegic homolog 3 isoform 2...
SMAD9                 0.160   SMAD family member 9 isoform b 
SMAD3                 0.160   mothers against decapentaplegic homolog 3 isoform 4...
SMAD4                 0.158   mothers against decapentaplegic homolog 4 
SMAD9                 0.154   SMAD family member 9 isoform a 
SMAD1                 0.151   Sma- and Mad-related protein 1 
SMAD1                 0.151   Sma- and Mad-related protein 1 
SMAD5                 0.151   SMAD, mothers against DPP homolog 5 
SMAD5                 0.151   SMAD, mothers against DPP homolog 5 
SMAD5                 0.151   SMAD, mothers against DPP homolog 5 
CRNKL1                0.015   crooked neck-like 1 protein 
TRAF3IP2              0.011   TRAF3 interacting protein 2 isoform 1 
TRAF3IP2              0.011   TRAF3 interacting protein 2 isoform 2 
TET2                  0.011   tet oncogene family member 2 isoform a 
LOC100133142          0.011   PREDICTED: similar to zinc finger protein 208 [Homo...
LOC100133142          0.011   PREDICTED: similar to zinc finger protein 208 [Homo...
MLL2                  0.011   myeloid/lymphoid or mixed-lineage leukemia 2 
RNF212                0.009   ring finger protein 212 isoform b 
NDUFA4L2              0.009   NADH:ubiquinone oxidoreductase MLRQ subunit homolog ...
PTCH1                 0.006   patched isoform S 
PTCH1                 0.006   patched isoform S 
PTCH1                 0.006   patched isoform S 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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