Guide to the Human Genome
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Name: SMAD6 Sequence: fasta or formatted (496aa) NCBI GI: 92859871
Description:

SMAD family member 6 isoform 1

Referenced in:

TGF-beta Family

Other entries for this name:
alt prot [235aa] SMAD family member 6 isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.5         42           4
 C cysteine            3.0         15           2
 D aspartate           5.2         26           1
 E glutamate           6.5         32           2
 F phenylalanine       2.8         14           1
 G glycine            11.7         58           6
 H histidine           1.4          7           1
 I isoleucine          1.8          9           1
 K lysine              2.4         12           1
 L leucine             9.9         49           4
 M methionine          0.6          3           1
 N asparagine          1.6          8           2
 P proline             9.9         49           4
 Q glutamine           2.4         12           1
 R arginine           10.3         51           4
 S serine              9.1         45           2
 T threonine           3.2         16           1
 V valine              5.4         27           2
 W tryptophan          1.6          8           1
 Y tyrosine            2.6         13           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SMAD family member 6 isoform 1 
SMAD6                 0.443   SMAD family member 6 isoform 2 
SMAD7                 0.346   SMAD family member 7 
SMAD2                 0.116   Sma- and Mad-related protein 2 isoform 2 
SMAD9                 0.114   SMAD family member 9 isoform b 
SMAD3                 0.113   mothers against decapentaplegic homolog 3 isoform 1 [...
SMAD2                 0.105   Sma- and Mad-related protein 2 isoform 1 
SMAD2                 0.105   Sma- and Mad-related protein 2 isoform 1 
SMAD3                 0.102   mothers against decapentaplegic homolog 3 isoform 3...
SMAD3                 0.085   mothers against decapentaplegic homolog 3 isoform 2...
SMAD3                 0.075   mothers against decapentaplegic homolog 3 isoform 4...
SMAD4                 0.074   mothers against decapentaplegic homolog 4 
SMAD9                 0.072   SMAD family member 9 isoform a 
SMAD5                 0.070   SMAD, mothers against DPP homolog 5 
SMAD5                 0.070   SMAD, mothers against DPP homolog 5 
SMAD5                 0.070   SMAD, mothers against DPP homolog 5 
SMAD1                 0.070   Sma- and Mad-related protein 1 
SMAD1                 0.070   Sma- and Mad-related protein 1 
LOC100288796          0.023   PREDICTED: hypothetical protein 
LOC100288796          0.023   PREDICTED: hypothetical protein XP_002343710 
ATXN2                 0.022   ataxin 2 
COL1A2                0.020   alpha 2 type I collagen 
LOC100287499          0.020   PREDICTED: hypothetical protein 
LOC100287499          0.020   PREDICTED: hypothetical protein XP_002343643 
COL3A1                0.019   collagen type III alpha 1 preproprotein 
MARCKS                0.019   myristoylated alanine-rich protein kinase C substra...
COL11A2               0.019   collagen, type XI, alpha 2 isoform 2 preproprotein ...
COL11A2               0.019   collagen, type XI, alpha 2 isoform 3 preproprotein ...
COL11A2               0.019   collagen, type XI, alpha 2 isoform 1 preproprotein ...
HCN4                  0.018   hyperpolarization activated cyclic nucleotide-gated p...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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