Guide to the Human Genome
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Name: SMAD3 Sequence: fasta or formatted (320aa) NCBI GI: 223029440
Description:

mothers against decapentaplegic homolog 3 isoform 2

Referenced in:

Myc and Related Functions
TGF-beta Family

Other entries for this name:
alt prot [381aa] mothers against decapentaplegic homolog 3 isoform 3
alt prot [230aa] mothers against decapentaplegic homolog 3 isoform 4
alt prot [425aa] mothers against decapentaplegic homolog 3 isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.3         17           2
 C cysteine            3.8         12           1
 D aspartate           3.4         11           2
 E glutamate           6.9         22           1
 F phenylalanine       4.4         14           1
 G glycine             5.6         18           2
 H histidine           3.1         10           1
 I isoleucine          4.1         13           1
 K lysine              1.9          6           2
 L leucine             7.5         24           2
 M methionine          2.8          9           1
 N asparagine          6.9         22           2
 P proline             9.4         30           3
 Q glutamine           4.7         15           1
 R arginine            4.7         15           2
 S serine              8.4         27           2
 T threonine           5.3         17           1
 V valine              6.6         21           1
 W tryptophan          1.6          5           1
 Y tyrosine            3.8         12           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mothers against decapentaplegic homolog 3 isoform 2... 
SMAD3                 1.000   mothers against decapentaplegic homolog 3 isoform 1 [...
SMAD3                 1.000   mothers against decapentaplegic homolog 3 isoform 3...
SMAD2                 0.907   Sma- and Mad-related protein 2 isoform 1 
SMAD2                 0.907   Sma- and Mad-related protein 2 isoform 1 
SMAD2                 0.907   Sma- and Mad-related protein 2 isoform 2 
SMAD3                 0.705   mothers against decapentaplegic homolog 3 isoform 4...
SMAD5                 0.592   SMAD, mothers against DPP homolog 5 
SMAD5                 0.592   SMAD, mothers against DPP homolog 5 
SMAD5                 0.592   SMAD, mothers against DPP homolog 5 
SMAD1                 0.586   Sma- and Mad-related protein 1 
SMAD1                 0.586   Sma- and Mad-related protein 1 
SMAD9                 0.579   SMAD family member 9 isoform b 
SMAD9                 0.568   SMAD family member 9 isoform a 
SMAD4                 0.237   mothers against decapentaplegic homolog 4 
SMAD6                 0.131   SMAD family member 6 isoform 1 
SMAD6                 0.116   SMAD family member 6 isoform 2 
SMAD7                 0.110   SMAD family member 7 
YLPM1                 0.015   YLP motif containing 1 
LOC100291908          0.014   PREDICTED: hypothetical protein XP_002345432 
PTPN23                0.012   protein tyrosine phosphatase, non-receptor type 23 [...
FBRSL1                0.011   fibrosin-like 1 
C13orf23              0.011   hypothetical protein LOC80209 isoform 2 
C13orf23              0.011   hypothetical protein LOC80209 isoform 1 
FMN1                  0.009   formin 1 
SOS2                  0.009   son of sevenless homolog 2 
ITGAX                 0.009   integrin alpha X precursor 
C6orf58               0.009   hypothetical protein LOC352999 
SNAI2                 0.008   snail 2 
MAP4K1                0.008   mitogen-activated protein kinase kinase kinase kina...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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