Guide to the Human Genome
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Name: SMAD3 Sequence: fasta or formatted (425aa) NCBI GI: 5174513
Description:

mothers against decapentaplegic homolog 3 isoform 1

Referenced in:

Myc and Related Functions
TGF-beta Family

Other entries for this name:
alt prot [320aa] mothers against decapentaplegic homolog 3 isoform 2
alt prot [381aa] mothers against decapentaplegic homolog 3 isoform 3
alt prot [230aa] mothers against decapentaplegic homolog 3 isoform 4
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.7         20           2
 C cysteine            3.5         15           1
 D aspartate           3.3         14           2
 E glutamate           6.8         29           2
 F phenylalanine       3.5         15           1
 G glycine             5.6         24           2
 H histidine           3.5         15           2
 I isoleucine          4.5         19           1
 K lysine              4.5         19           2
 L leucine             8.7         37           2
 M methionine          2.4         10           1
 N asparagine          5.9         25           2
 P proline             8.5         36           3
 Q glutamine           4.7         20           1
 R arginine            5.2         22           2
 S serine              7.8         33           2
 T threonine           5.4         23           2
 V valine              6.4         27           1
 W tryptophan          2.1          9           1
 Y tyrosine            3.1         13           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mothers against decapentaplegic homolog 3 isoform 1 [... 
SMAD2                 0.915   Sma- and Mad-related protein 2 isoform 2 
SMAD2                 0.897   Sma- and Mad-related protein 2 isoform 1 
SMAD2                 0.897   Sma- and Mad-related protein 2 isoform 1 
SMAD3                 0.844   mothers against decapentaplegic homolog 3 isoform 3...
SMAD3                 0.749   mothers against decapentaplegic homolog 3 isoform 2...
SMAD5                 0.616   SMAD, mothers against DPP homolog 5 
SMAD5                 0.616   SMAD, mothers against DPP homolog 5 
SMAD5                 0.616   SMAD, mothers against DPP homolog 5 
SMAD1                 0.606   Sma- and Mad-related protein 1 
SMAD1                 0.606   Sma- and Mad-related protein 1 
SMAD9                 0.606   SMAD family member 9 isoform b 
SMAD9                 0.598   SMAD family member 9 isoform a 
SMAD3                 0.529   mothers against decapentaplegic homolog 3 isoform 4...
SMAD4                 0.283   mothers against decapentaplegic homolog 4 
SMAD6                 0.130   SMAD family member 6 isoform 1 
SMAD7                 0.117   SMAD family member 7 
SMAD6                 0.087   SMAD family member 6 isoform 2 
YLPM1                 0.011   YLP motif containing 1 
LOC100291908          0.010   PREDICTED: hypothetical protein XP_002345432 
MAP4K1                0.009   mitogen-activated protein kinase kinase kinase kina...
MAP4K1                0.009   mitogen-activated protein kinase kinase kinase kinase...
PTPN23                0.009   protein tyrosine phosphatase, non-receptor type 23 [...
FBRSL1                0.008   fibrosin-like 1 
C13orf23              0.008   hypothetical protein LOC80209 isoform 2 
C13orf23              0.008   hypothetical protein LOC80209 isoform 1 
FMN1                  0.007   formin 1 
SOS2                  0.007   son of sevenless homolog 2 
ITGAX                 0.007   integrin alpha X precursor 
C6orf58               0.007   hypothetical protein LOC352999 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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