Guide to the Human Genome
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Name: SMAD3 Sequence: fasta or formatted (381aa) NCBI GI: 223029442
Description:

mothers against decapentaplegic homolog 3 isoform 3

Referenced in:

Myc and Related Functions
TGF-beta Family

Other entries for this name:
alt prot [320aa] mothers against decapentaplegic homolog 3 isoform 2
alt prot [230aa] mothers against decapentaplegic homolog 3 isoform 4
alt prot [425aa] mothers against decapentaplegic homolog 3 isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.5         21           2
 C cysteine            3.7         14           1
 D aspartate           3.4         13           2
 E glutamate           6.0         23           1
 F phenylalanine       3.7         14           1
 G glycine             5.8         22           2
 H histidine           4.5         17           2
 I isoleucine          3.7         14           1
 K lysine              2.4          9           2
 L leucine             8.4         32           2
 M methionine          2.9         11           1
 N asparagine          5.8         22           2
 P proline             8.7         33           3
 Q glutamine           4.5         17           1
 R arginine            6.0         23           2
 S serine              8.1         31           2
 T threonine           4.7         18           1
 V valine              6.3         24           1
 W tryptophan          2.6         10           2
 Y tyrosine            3.4         13           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mothers against decapentaplegic homolog 3 isoform 3... 
SMAD3                 0.931   mothers against decapentaplegic homolog 3 isoform 1 [...
SMAD2                 0.851   Sma- and Mad-related protein 2 isoform 1 
SMAD2                 0.851   Sma- and Mad-related protein 2 isoform 1 
SMAD2                 0.851   Sma- and Mad-related protein 2 isoform 2 
SMAD3                 0.826   mothers against decapentaplegic homolog 3 isoform 2...
SMAD5                 0.584   SMAD, mothers against DPP homolog 5 
SMAD5                 0.584   SMAD, mothers against DPP homolog 5 
SMAD5                 0.584   SMAD, mothers against DPP homolog 5 
SMAD3                 0.583   mothers against decapentaplegic homolog 3 isoform 4...
SMAD1                 0.579   Sma- and Mad-related protein 1 
SMAD1                 0.579   Sma- and Mad-related protein 1 
SMAD9                 0.573   SMAD family member 9 isoform b 
SMAD9                 0.564   SMAD family member 9 isoform a 
SMAD4                 0.227   mothers against decapentaplegic homolog 4 
SMAD6                 0.130   SMAD family member 6 isoform 1 
SMAD7                 0.113   SMAD family member 7 
SMAD6                 0.096   SMAD family member 6 isoform 2 
YLPM1                 0.013   YLP motif containing 1 
LOC100291908          0.011   PREDICTED: hypothetical protein XP_002345432 
PTPN23                0.010   protein tyrosine phosphatase, non-receptor type 23 [...
FBRSL1                0.009   fibrosin-like 1 
C13orf23              0.009   hypothetical protein LOC80209 isoform 2 
C13orf23              0.009   hypothetical protein LOC80209 isoform 1 
FMN1                  0.008   formin 1 
SOS2                  0.008   son of sevenless homolog 2 
ITGAX                 0.008   integrin alpha X precursor 
ANKMY1                0.008   ankyrin repeat and MYND domain containing 1 isoform ...
C6orf58               0.008   hypothetical protein LOC352999 
SNAI2                 0.006   snail 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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