Guide to the Human Genome
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Name: SMAD7 Sequence: fasta or formatted (426aa) NCBI GI: 5174517
Description:

SMAD family member 7

Referenced in:

TGF-beta Family

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.3         31           2
 C cysteine            4.5         19           3
 D aspartate           4.2         18           1
 E glutamate           5.6         24           3
 F phenylalanine       3.3         14           1
 G glycine            11.5         49           7
 H histidine           2.8         12           3
 I isoleucine          2.3         10           1
 K lysine              4.7         20           2
 L leucine            10.6         45           3
 M methionine          0.7          3           1
 N asparagine          2.3         10           1
 P proline             7.7         33           4
 Q glutamine           4.0         17           2
 R arginine            7.0         30           2
 S serine              7.7         33           2
 T threonine           3.5         15           1
 V valine              5.2         22           2
 W tryptophan          1.9          8           1
 Y tyrosine            3.1         13           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SMAD family member 7 
SMAD6                 0.398   SMAD family member 6 isoform 1 
SMAD6                 0.253   SMAD family member 6 isoform 2 
SMAD2                 0.122   Sma- and Mad-related protein 2 isoform 2 
SMAD3                 0.116   mothers against decapentaplegic homolog 3 isoform 1 [...
SMAD2                 0.113   Sma- and Mad-related protein 2 isoform 1 
SMAD2                 0.113   Sma- and Mad-related protein 2 isoform 1 
SMAD9                 0.107   SMAD family member 9 isoform b 
SMAD3                 0.103   mothers against decapentaplegic homolog 3 isoform 3...
SMAD9                 0.086   SMAD family member 9 isoform a 
SMAD3                 0.082   mothers against decapentaplegic homolog 3 isoform 2...
SMAD1                 0.076   Sma- and Mad-related protein 1 
SMAD1                 0.076   Sma- and Mad-related protein 1 
SMAD5                 0.076   SMAD, mothers against DPP homolog 5 
SMAD5                 0.076   SMAD, mothers against DPP homolog 5 
SMAD5                 0.076   SMAD, mothers against DPP homolog 5 
SMAD3                 0.073   mothers against decapentaplegic homolog 3 isoform 4...
SMAD4                 0.072   mothers against decapentaplegic homolog 4 
POU4F1                0.029   POU domain, class 4, transcription factor 1 
HNRNPL                0.022   heterogeneous nuclear ribonucleoprotein L isoform a ...
CTAG1B                0.019   cancer/testis antigen 1B 
CTAG1A                0.019   cancer/testis antigen 1A 
CACNG8                0.019   voltage-dependent calcium channel gamma-8 subunit [H...
SOX4                  0.019   SRY (sex determining region Y)-box 4 
FAM98B                0.019   family with sequence similarity 98, member B isofor...
HOXD11                0.018   homeobox D11 
PPP1R10               0.018   protein phosphatase 1, regulatory subunit 10 
DACH1                 0.018   dachshund homolog 1 isoform b 
DACH1                 0.018   dachshund homolog 1 isoform a 
DACH1                 0.018   dachshund homolog 1 isoform c 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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