Guide to the Human Genome
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Search of human proteins with 4885375

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4885375 histone cluster 1, H1c [Homo sapiens]
         (213 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4885375 histone cluster 1, H1c [Homo sapiens]                      405   e-113
gi|4885379 histone cluster 1, H1e [Homo sapiens]                      341   3e-94
gi|4885377 histone cluster 1, H1d [Homo sapiens]                      326   1e-89
gi|4885381 histone cluster 1, H1b [Homo sapiens]                      299   1e-81
gi|4885373 histone cluster 1, H1a [Homo sapiens]                      245   2e-65
gi|20544168 histone cluster 1, H1t [Homo sapiens]                     172   2e-43
gi|4885371 H1 histone family, member 0 [Homo sapiens]                 116   1e-26
gi|5174449 H1 histone family, member X [Homo sapiens]                 100   7e-22
gi|24475863 H1 histone family, member O, oocyte-specific [Homo s...    68   5e-12
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     65   4e-11
gi|32401437 H1 histone family, member N, testis-specific [Homo s...    60   2e-09
gi|111548666 SNF2 histone linker PHD RING helicase isoform a [Ho...    57   2e-08
gi|27436873 SNF2 histone linker PHD RING helicase isoform b [Hom...    57   2e-08
gi|153070260 myristoylated alanine-rich protein kinase C substra...    56   2e-08
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          52   4e-07
gi|56676330 HP1-BP74 [Homo sapiens]                                    49   2e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   49   3e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   49   3e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   49   3e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    49   3e-06
gi|9257222 forkhead box O1 [Homo sapiens]                              48   5e-06
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    48   5e-06
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]            48   7e-06
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo...    47   9e-06
gi|55956788 nucleolin [Homo sapiens]                                   45   5e-05
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s...    45   6e-05
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s...    45   6e-05
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ...    45   6e-05
gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sa...    45   6e-05
gi|118498359 ribosomal L1 domain containing 1 [Homo sapiens]           44   8e-05

>gi|4885375 histone cluster 1, H1c [Homo sapiens]
          Length = 213

 Score =  405 bits (1041), Expect = e-113
 Identities = 213/213 (100%), Positives = 213/213 (100%)

Query: 1   MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA 60
           MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA
Sbjct: 1   MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA 60

Query: 61  ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV 120
           ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV
Sbjct: 61  ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV 120

Query: 121 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA 180
           KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA
Sbjct: 121 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA 180

Query: 181 KPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK 213
           KPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK
Sbjct: 181 KPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK 213


>gi|4885379 histone cluster 1, H1e [Homo sapiens]
          Length = 219

 Score =  341 bits (874), Expect = 3e-94
 Identities = 186/214 (86%), Positives = 186/214 (86%), Gaps = 3/214 (1%)

Query: 1   MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA 60
           MSETAPAAPAA  PAEK PVKKKA K AG   RKASGPPVSELITKAVAASKERSGVSLA
Sbjct: 1   MSETAPAAPAAPAPAEKTPVKKKARKSAGAAKRKASGPPVSELITKAVAASKERSGVSLA 60

Query: 61  ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV 120
           ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK 
Sbjct: 61  ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKA 120

Query: 121 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA 180
           KKAG  K KKP GAAKKPKKA G ATPKKSAKKTPKKAKKPAAA   KK AKSPKKAK A
Sbjct: 121 KKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKK-AKSPKKAKAA 179

Query: 181 KPKKAAKS--AAKAVKPKAAKPKVVKPKKAAPKK 212
           KPKKA KS   AKAVKPKAAKPK  KPK A PKK
Sbjct: 180 KPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKK 213


>gi|4885377 histone cluster 1, H1d [Homo sapiens]
          Length = 221

 Score =  326 bits (835), Expect = 1e-89
 Identities = 180/222 (81%), Positives = 183/222 (82%), Gaps = 10/222 (4%)

Query: 1   MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTP--RKASGPPVSELITKAVAASKERSGVS 58
           MSETAP AP    PAEK PVKKKA KKAG T   RKASGPPVSELITKAVAASKERSGVS
Sbjct: 1   MSETAPLAPTIPAPAEKTPVKKKA-KKAGATAGKRKASGPPVSELITKAVAASKERSGVS 59

Query: 59  LAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKP 118
           LAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGE KP
Sbjct: 60  LAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGKP 119

Query: 119 KVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAK 178
           K KKAG  KP+KP GAAKKPKK AG ATPKKS KKTPKK KKPA A  TKKVAKS KK K
Sbjct: 120 KAKKAGAAKPRKPAGAAKKPKKVAGAATPKKSIKKTPKKVKKPATAAGTKKVAKSAKKVK 179

Query: 179 VAKPKKAAKSAA-------KAVKPKAAKPKVVKPKKAAPKKK 213
             +PKKAAKS A       KA KPK+ KPKV K KKAAPKKK
Sbjct: 180 TPQPKKAAKSPAKAKAPKPKAAKPKSGKPKVTKAKKAAPKKK 221


>gi|4885381 histone cluster 1, H1b [Homo sapiens]
          Length = 226

 Score =  299 bits (765), Expect = 1e-81
 Identities = 171/217 (78%), Positives = 176/217 (81%), Gaps = 9/217 (4%)

Query: 1   MSETAPAAPAAAPPAEKAPVKKKAAKKAGGT---PRKASGPPVSELITKAVAASKERSGV 57
           MSETAPA  A   P EK+P KKKA KKA G     RKA+GPPVSELITKAVAASKER+G+
Sbjct: 1   MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL 60

Query: 58  SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 117
           SLAALKKALAA GYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
Sbjct: 61  SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 120

Query: 118 PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKA 177
           PK KKAG  K KKP GA  K  K A GA  KK+ KKTPKKAKKPAAA V KKVAKSPKKA
Sbjct: 121 PKAKKAGAAKAKKPAGATPKKAKKAAGA--KKAVKKTPKKAKKPAAAGV-KKVAKSPKKA 177

Query: 178 K-VAKPKKAAKSAA--KAVKPKAAKPKVVKPKKAAPK 211
           K  AKPKKA KS A  KAVKPKAAKPK  KPK A PK
Sbjct: 178 KAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPK 214


>gi|4885373 histone cluster 1, H1a [Homo sapiens]
          Length = 215

 Score =  245 bits (625), Expect = 2e-65
 Identities = 149/223 (66%), Positives = 164/223 (73%), Gaps = 18/223 (8%)

Query: 1   MSETAPAAPAAAPPAEKAPVKKKA---AKKAGGTPRKASGPPVSELITKAVAASKERSGV 57
           MSET P APAA+   EK    KKA   AK A  + +K +GP VSELI +A ++SKER GV
Sbjct: 1   MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV 60

Query: 58  SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 117
           SLAALKKALAAAGYDVEKNNSRIKLG+KSLVSKGTLVQTKGTGASGSFKLNKKA+S E K
Sbjct: 61  SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK 120

Query: 118 PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKA 177
           P   K   TK  K  GA+KK KKA G +   K + KTPKKAKKPAA   T+K +K+PKK 
Sbjct: 121 PGASKV-ATK-TKATGASKKLKKATGAS---KKSVKTPKKAKKPAA---TRKSSKNPKKP 172

Query: 178 KVAKPKKAAKS--AAKAVKPKAA-----KPKVVKPKKAAPKKK 213
           K  KPKK AKS   AKAVKPKAA     KPK  KPKKAAPKKK
Sbjct: 173 KTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK 215


>gi|20544168 histone cluster 1, H1t [Homo sapiens]
          Length = 207

 Score =  172 bits (436), Expect = 2e-43
 Identities = 116/220 (52%), Positives = 138/220 (62%), Gaps = 21/220 (9%)

Query: 1   MSETAPAAPAAAPPA--EKAPVKKKAAKKAG--GTPRKASGPPVSELITKAVAASKERSG 56
           MSET PAA A+A  A  EK P KK+  K AG     RK     VS+LIT+A++ S+ER G
Sbjct: 1   MSETVPAASASAGVAAMEKLPTKKRGRKPAGLISASRKVPNLSVSKLITEALSVSQERVG 60

Query: 57  VSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEA 116
           +SL ALKKALAAAGYDVEKNNSRIKL LKSLV+KG LVQT+GTGASGSFKL+KK      
Sbjct: 61  MSLVALKKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKST 120

Query: 117 KPKVKKAGGTKPKKPVGA--AKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSP 174
           + K KK+   K KK V +  +K PK A           KT K+AKKP A   T K  +S 
Sbjct: 121 RSKAKKSVSAKTKKLVLSRDSKSPKTA-----------KTNKRAKKPRA--TTPKTVRSG 167

Query: 175 KKAKVAKPKKAAKS--AAKAVKPKAAKPKVVKPKKAAPKK 212
           +KAK AK K+  KS   A+A K K  +   V  +KA  KK
Sbjct: 168 RKAKGAKGKQQQKSPVKARASKSKLTQHHEVNVRKATSKK 207


>gi|4885371 H1 histone family, member 0 [Homo sapiens]
          Length = 194

 Score =  116 bits (291), Expect = 1e-26
 Identities = 89/219 (40%), Positives = 114/219 (52%), Gaps = 31/219 (14%)

Query: 1   MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA 60
           M+E + +APAA P            K+A  + +    P  S++I  A+ A K R+G S  
Sbjct: 1   MTENSTSAPAAKP------------KRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQ 48

Query: 61  ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV 120
           +++K + +     E  +S+IKL +K LV+ G L QTKG GASGSF+L   A S E K   
Sbjct: 49  SIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRL---AKSDEPK--- 102

Query: 121 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTP-KKAKKPAAATVTKKVAKSPKKAKV 179
           K     K KK +     PKKA   + PKK+A K P KK K        KK+A +PKKAK 
Sbjct: 103 KSVAFKKTKKEIKKVATPKKA---SKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAK- 158

Query: 180 AKPKKAAKSAAKAVKPKAAKPKVVKPK-----KAAPKKK 213
            KPK       KA KPK AKP  VKPK     K A KKK
Sbjct: 159 -KPKTVKAKPVKASKPKKAKP--VKPKAKSSAKRAGKKK 194


>gi|5174449 H1 histone family, member X [Homo sapiens]
          Length = 213

 Score =  100 bits (250), Expect = 7e-22
 Identities = 73/198 (36%), Positives = 98/198 (49%), Gaps = 12/198 (6%)

Query: 11  AAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAAL-KKALAAA 69
           A   A  +P KK+   K    P K      S+L+ + +    ER+G SLA +  +A    
Sbjct: 24  AGGSAALSPSKKRKNSKKKNQPGK-----YSQLVVETIRRLGERNGSSLAKIYTEAKKVP 78

Query: 70  GYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKKAGGTKPK 129
            +D +   + +K  +K+LV   TL+Q KGTGA+GSFKLN+K   G  + +   A  T   
Sbjct: 79  WFDQQNGRTYLKYSIKALVQNDTLLQVKGTGANGSFKLNRKKLEGGGERRGAPAAAT--- 135

Query: 130 KPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVAKPKKAAKSA 189
            P   A K KKAA GA   + A K P + +KP     + K     KK K  K KK A + 
Sbjct: 136 APAPTAHKAKKAAPGAAGSRRADKKPARGQKPEQR--SHKKGAGAKKDKGGKAKKTAAAG 193

Query: 190 AKAVKPKAAKPKVVKPKK 207
            K VK KAAKP V K  K
Sbjct: 194 GKKVK-KAAKPSVPKVPK 210


>gi|24475863 H1 histone family, member O, oocyte-specific [Homo
           sapiens]
          Length = 346

 Score = 68.2 bits (165), Expect = 5e-12
 Identities = 64/217 (29%), Positives = 93/217 (42%), Gaps = 25/217 (11%)

Query: 2   SETAPAAPAAAPPAEKAPVKKKAAKKAGGT-----PRKASGPPVSELITKAVAASKERSG 56
           S T+ A  + +P +EK P         GG      P     PPV  ++ +A+ A ++R G
Sbjct: 13  SSTSTAGSSRSPESEK-PGPSHGGVPPGGPSHSSLPVGRRHPPVLRMVLEALQAGEQRRG 71

Query: 57  VSLAALKKALAAA--GYDVEKNNSRIKLGLKSLVSKGTLVQ---TKGTGASGSFKL---- 107
            S+AA+K  +       DV +    +K  L + + +G L +   +K  GA+GSFKL    
Sbjct: 72  TSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKARGATGSFKLVPKH 131

Query: 108 -----NKKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPA 162
                 +K A   A  +  +A G  PKKP  A + P          K   K  K   KP 
Sbjct: 132 KKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPG 191

Query: 163 AATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAK 199
           AAT      K+ K+   AK  +A    A+ V PK  K
Sbjct: 192 AAT-----EKARKQGGAAKDTRAQSGEARKVPPKPDK 223



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 53/205 (25%), Positives = 77/205 (37%), Gaps = 19/205 (9%)

Query: 3   ETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAAL 62
           E     P     A++ P      KKA   P K   PP          A+ E++     A 
Sbjct: 151 EAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKP------GAATEKARKQGGAA 204

Query: 63  KKALAAAGYDVEKNNSRIKLGLKSLVSKGTL---VQTKGTGAS---GSFKLNKKAASGEA 116
           K   A +G +  K   +    +++  S G L    + KG+ +S          KA S  +
Sbjct: 205 KDTRAQSG-EARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSS 263

Query: 117 KPKVKKA--GGTKP--KKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAK 172
           KP   K   G   P  KK V  AK PK   G  T   +  K       PA  +   +  K
Sbjct: 264 KPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPK 323

Query: 173 SPKKAKVAKPKKAAKSAAKAVKPKA 197
            P+KA +  P KA+ S   + + +A
Sbjct: 324 GPRKAGL--PIKASSSKVSSQRAEA 346


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 65.1 bits (157), Expect = 4e-11
 Identities = 69/221 (31%), Positives = 101/221 (45%), Gaps = 23/221 (10%)

Query: 10  AAAPPAEKAPVKKKAAKKAG-GTPRKASGPPVSELITKAVAASKERSGVSLAALKKALAA 68
           A +PP  K+P K++A   A   +P KA  P   E  + A A S E++   +    K+ A 
Sbjct: 558 AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE 617

Query: 69  AGYDV-EKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKKAGGT- 126
           A   V E+  S  ++         T  + K    + S +  +  +  +AK  VK    + 
Sbjct: 618 AKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSP 677

Query: 127 -KPKKPVGA-AKKPKKAAG-----------GATPKKSAKKTPKKAKKPAAATVTKKVAKS 173
            K K PV A AK P+KA               +P K   K+P+KAK P      K+ AK+
Sbjct: 678 EKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP-----VKEEAKT 732

Query: 174 PKKAKVAKPKKAAKSAAKAVKPKAAKPKVVK-PKKAAPKKK 213
           P+KAK +  K+ AKS  KA  P+ AK   VK P+   P K+
Sbjct: 733 PEKAK-SPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKE 772



 Score = 54.3 bits (129), Expect = 8e-08
 Identities = 72/241 (29%), Positives = 99/241 (41%), Gaps = 32/241 (13%)

Query: 5   APAAPAAAPPAE-KAPVKKKAAKKAG-GTPRKASGPPVSELITKAVAASKERSGV-SLAA 61
           +P    A  PAE K+PVK++A   A   +P KA  P   E  +   A S E+    S   
Sbjct: 606 SPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK 665

Query: 62  LKKALAAAGYDVEKNNSRIKLGLKSLV-SKGTLVQTKGTGASGSFKLNKKAASGE-AKPK 119
            K  + A     EK  S +K   KS   +K  + +   +       + ++A S E AK  
Sbjct: 666 AKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725

Query: 120 VKKAGGT--KPKKPVGA-AKKPKKAAG-------------GATPKKS-----AKKTPKKA 158
           VK+   T  K K PV   AK P+KA                 TP K      A K P+KA
Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA 785

Query: 159 KKPAAATV-TKKVAKSPKKAKVAKPKKAAKSAAKAVKP-----KAAKPKVVKPKKAAPKK 212
           K P    V + + AKSP K     P+K      +   P     K  + KV +P K A ++
Sbjct: 786 KSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845

Query: 213 K 213
           K
Sbjct: 846 K 846



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 67/215 (31%), Positives = 92/215 (42%), Gaps = 26/215 (12%)

Query: 8   APAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELIT--KAVAASKERSGVSLAALKKA 65
           A A +P   K+PVK++A      +P KA  P   E  +  KA +  KE +     A K  
Sbjct: 686 AEAKSPEKAKSPVKEEAK-----SPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKA-KSP 739

Query: 66  LAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKKAGG 125
           +       EK  S  K     + S       K    S + K  +KA S   K +VK    
Sbjct: 740 VKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKS-PVKEEVKS--- 795

Query: 126 TKPKKPVGAAKKPKKAAGGATPKKSAKKTP-KKAKKPAAATVTKKVAKSPKKAKVAK--- 181
             P+K     K+  KA     PKK   K+P K+ +KP       KV + PKKA+  K   
Sbjct: 796 --PEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEV----KVKEPPKKAEEEKAPA 849

Query: 182 -PKKAAKSAAK---AVKPKAAKPKVVKPKKAAPKK 212
            PK   K  +K   A K +A KPKV + K+ A +K
Sbjct: 850 TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884



 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 61/215 (28%), Positives = 99/215 (46%), Gaps = 17/215 (7%)

Query: 2   SETAPAAPAAAPPAE-KAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA 60
           +++ PA  AA+P  E K+PVK++A      +P +A  P   E  + A   S E++     
Sbjct: 501 TKSPPAEEAASPEKEAKSPVKEEAK-----SPAEAKSPEKEEAKSPAEVKSPEKAKSPAK 555

Query: 61  ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGE-AKPK 119
              K+   A    EK  ++    +KS        +   + A    K   +A S E AK  
Sbjct: 556 EEAKSPPEAK-SPEKEEAKSPAEVKS-------PEKAKSPAKEEAKSPAEAKSPEKAKSP 607

Query: 120 VKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKP-AAATVTKKVAKSPKKAK 178
           VK+   +  +      ++ K  A   +P+K+   T ++AK P  A +  K+ AKSP+KAK
Sbjct: 608 VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAK 667

Query: 179 VAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK 213
            +  K  AKS  KA  P  A+ K  +  K+  K++
Sbjct: 668 -SPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEE 701



 Score = 47.8 bits (112), Expect = 7e-06
 Identities = 60/233 (25%), Positives = 95/233 (40%), Gaps = 32/233 (13%)

Query: 6   PAAPAAAPPAEKAPVKKKA-AKKAGGTPRKASGP------------PVSELITKAVAASK 52
           PA   A  PA+K P K K+  K+   +P KA  P            P  E +   V   +
Sbjct: 769 PAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEE 828

Query: 53  ERSGVSLA-----ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKL 107
           +   V +      A ++   A     EK +S+ +   K    K  + + K        + 
Sbjct: 829 KPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKES 888

Query: 108 NKKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTP--KKAKKPAAAT 165
             +A   EA+ K K      P+K   A  + K+ A      + AKK P   KAK+P+   
Sbjct: 889 KVEAKKEEAEDKKKVP---TPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPA 945

Query: 166 VTKKVA---KSPKKAKVAKPKKAAKSAAKA------VKPKAAKPKVVKPKKAA 209
             K+ A   K  K+ K  KP++  K+ AKA      +  + +KPK  K +K++
Sbjct: 946 EKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSS 998



 Score = 47.4 bits (111), Expect = 9e-06
 Identities = 62/208 (29%), Positives = 94/208 (45%), Gaps = 24/208 (11%)

Query: 14  PAEKAPVKKKAAKKAGGTPRKASGPPVSELIT--KAVAASKERSGVSLAAL-KKALAAAG 70
           P  K P K++A   A   P KA  P   E+ +  KA +  KE +      + KK    + 
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP 823

Query: 71  YDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKK--AASGEA-KPKVKKAGGTK 127
              E+    +K+  K    K    +   T  +   K +KK  A   EA KPKV++     
Sbjct: 824 VKEEEKPQEVKV--KEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEK---- 877

Query: 128 PKKPVGAAKKPKKAAGGATPKKS--AKKTPKKAKKPAAATVTKKVAKSPKKAKVAKPKKA 185
            K+P  A +KPK++   A  +++   KK P   K+  A    K+ AK  +K +VAK +  
Sbjct: 878 -KEP--AVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKE-- 932

Query: 186 AKSAAKAVKPKAAKPKVVKPKKAAPKKK 213
               AKA +P     K  + K+AAP+KK
Sbjct: 933 -PDDAKAKEPS----KPAEKKEAAPEKK 955



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 52/188 (27%), Positives = 74/188 (39%), Gaps = 16/188 (8%)

Query: 9    PAAAPPAEKAPV-----KKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALK 63
            P      EKAP      +KK +KK     ++A  P V E    AV   KE    S    K
Sbjct: 838  PPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKE----SKVEAK 893

Query: 64   KALAAAGYDV----EKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK 119
            K  A     V    ++  +++++   +   + T V  K    + + + +K A   EA P+
Sbjct: 894  KEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPE 953

Query: 120  VKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKV 179
             K     K KKP    +KPK  A      K+  K P K K   A   +    K  K  + 
Sbjct: 954  KKDTKEEKAKKP---EEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEK 1010

Query: 180  AKPKKAAK 187
            A   KAAK
Sbjct: 1011 ATEDKAAK 1018



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 31/109 (28%), Positives = 54/109 (49%), Gaps = 5/109 (4%)

Query: 109 KKAASGEAK---PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKP-AAA 164
           ++A  GE +   P  ++A   + +      ++ K  A   +P+K   K+P + K P  A 
Sbjct: 492 EEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAK 551

Query: 165 TVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK 213
           +  K+ AKSP +AK +  K+ AKS A+   P+ AK    +  K+  + K
Sbjct: 552 SPAKEEAKSPPEAK-SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAK 599



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 44/145 (30%), Positives = 70/145 (48%), Gaps = 11/145 (7%)

Query: 75  KNNSRIKLGLKSLVSKGTLV---QTKGTGASGSFKLNKKAASGEAKPKVKKAGGTKPKKP 131
           K+  +IK+  KS   K T++   QT+ T  +      ++  + E + K ++ G  +  + 
Sbjct: 439 KSEEKIKVVEKS--EKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEG 496

Query: 132 VGAAKKPKKAAGGATPKKSAKKTPK-KAKKPA-AATVTKKVAKSPKKAKVAKPKKAAKSA 189
                K   A   A+P+K AK   K +AK PA A +  K+ AKSP  A+V  P+KA   A
Sbjct: 497 GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSP--AEVKSPEKAKSPA 554

Query: 190 AKAVK--PKAAKPKVVKPKKAAPKK 212
            +  K  P+A  P+  + K  A  K
Sbjct: 555 KEEAKSPPEAKSPEKEEAKSPAEVK 579


>gi|32401437 H1 histone family, member N, testis-specific [Homo
           sapiens]
          Length = 255

 Score = 59.7 bits (143), Expect = 2e-09
 Identities = 57/211 (27%), Positives = 102/211 (48%), Gaps = 31/211 (14%)

Query: 8   APAAAPPAEK---APVKKKAAKKAGGTPRKASGPP--VSELITKAVAASKERSGVSLAAL 62
           A A  P  E    +  +  A K  GG  R  S     VS+L+ +A++  K   G++LAAL
Sbjct: 23  AEAPGPSGESRGHSATQLPAEKTVGGPSRGCSSSVLRVSQLVLQAISTHK---GLTLAAL 79

Query: 63  KKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKK 122
           KK L  AGY+V + + R +       +K TL++  G+ A+G F++ K       KP+   
Sbjct: 80  KKELRNAGYEVRRKSGRHEAPRGQ--AKATLLRVSGSDAAGYFRVWK-----VPKPR--- 129

Query: 123 AGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVAKP 182
                 +KP  A ++    A   TP  +A ++ ++ ++P      +K A+  ++      
Sbjct: 130 ------RKPGRARQEEGTRAPWRTP--AAPRSSRRRRQP-----LRKAARKAREVWRRNA 176

Query: 183 KKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK 213
           +  AK+ A+A + + A+P+  +P  A  K++
Sbjct: 177 RAKAKANARARRTRRARPRAKEPPCARAKEE 207


>gi|111548666 SNF2 histone linker PHD RING helicase isoform a [Homo
           sapiens]
          Length = 1687

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 34/98 (34%), Positives = 51/98 (52%), Gaps = 1/98 (1%)

Query: 34  KASGPPVSELITKAVAASKERSGVSLAALKKALAAA-GYDVEKNNSRIKLGLKSLVSKGT 92
           K   PP   +I  AV     + GVS+ ++ K +++   YDV++N S +K  LK L+ +G 
Sbjct: 436 KVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNRSLLKRMLKCLIFEGL 495

Query: 93  LVQTKGTGASGSFKLNKKAASGEAKPKVKKAGGTKPKK 130
           + Q KG G SG+F L K     +   K KK     P+K
Sbjct: 496 VKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRK 533


>gi|27436873 SNF2 histone linker PHD RING helicase isoform b [Homo
           sapiens]
          Length = 1659

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 34/98 (34%), Positives = 51/98 (52%), Gaps = 1/98 (1%)

Query: 34  KASGPPVSELITKAVAASKERSGVSLAALKKALAAA-GYDVEKNNSRIKLGLKSLVSKGT 92
           K   PP   +I  AV     + GVS+ ++ K +++   YDV++N S +K  LK L+ +G 
Sbjct: 436 KVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNRSLLKRMLKCLIFEGL 495

Query: 93  LVQTKGTGASGSFKLNKKAASGEAKPKVKKAGGTKPKK 130
           + Q KG G SG+F L K     +   K KK     P+K
Sbjct: 496 VKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRK 533


>gi|153070260 myristoylated alanine-rich protein kinase C substrate
           [Homo sapiens]
          Length = 332

 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 58/231 (25%), Positives = 95/231 (41%), Gaps = 34/231 (14%)

Query: 2   SETAPAAPAAAPPAEKAPVKKKAAKKAG----GTPRKASGPPVSELITKAVAASKERSGV 57
           +E    A AAAP A  +PV+K+A  +      G+P  A G   S     + ++ K   G 
Sbjct: 85  AEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASA--ASSTSSPKAEDGA 142

Query: 58  SLA-------------ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGS 104
           + +             + KK+   +G+  +KN      G ++        + +  G + +
Sbjct: 143 TPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAA 202

Query: 105 FKLNKKAASGE--AKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPA 162
                 AASGE  A P  + A G +             AAGG   +   ++     +KP 
Sbjct: 203 AAAEAGAASGEQAAAPGEEAAAGEEG------------AAGGDPQEAKPQEAAVAPEKPP 250

Query: 163 AATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK 213
           A+  TK  A+ P K +  K ++A  SAA    P AA P     ++AAP ++
Sbjct: 251 ASDETK-AAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEE 300



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 29/119 (24%), Positives = 47/119 (39%), Gaps = 7/119 (5%)

Query: 102 SGSFKLNKKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKP 161
           +G  K+N  A+   A+   K+        P    ++P  A  GA    +A+K    A   
Sbjct: 36  NGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAA 95

Query: 162 AAATVTKKVAKSPKKAKVAKP-------KKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK 213
             A  +    ++P + + A+P        +AA +A+    PKA       P    PKKK
Sbjct: 96  PEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKK 154



 Score = 34.7 bits (78), Expect = 0.062
 Identities = 51/198 (25%), Positives = 68/198 (34%), Gaps = 16/198 (8%)

Query: 2   SETAPAAPAAAPPAEKAPVKKKAAKKAGGTPR--KASGPPVSELITKAVAASKERSGVSL 59
           S+TA    AAA    +A V    +K  G      K +G               + +G + 
Sbjct: 6   SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAP 65

Query: 60  AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK 119
           AA K+  AAAG               S   KG         A  S    +  A GEA   
Sbjct: 66  AADKEEPAAAGSGAAS---------PSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEP 116

Query: 120 VKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKV 179
                         ++    KA  GATP  S  +TPKK KK  +   + K++    K   
Sbjct: 117 GSPTAAEGEAASAASSTSSPKAEDGATPSPS-NETPKKKKKRFSFKKSFKLSGFSFK--- 172

Query: 180 AKPKKAAKSAAKAVKPKA 197
            K KK A    +A  P A
Sbjct: 173 -KNKKEAGEGGEAEAPAA 189



 Score = 28.5 bits (62), Expect = 4.4
 Identities = 27/106 (25%), Positives = 41/106 (38%), Gaps = 3/106 (2%)

Query: 106 KLNKKAASGEAKPKV--KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAA 163
           + +K AA GEA  +   + A  + P K  G      K  G A+P  +     ++ +   +
Sbjct: 4   QFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGS 63

Query: 164 ATVTKKVAKSPKKAKVAKPKKAAK-SAAKAVKPKAAKPKVVKPKKA 208
           A    K   +   +  A P  A K   A A  P+A    V K   A
Sbjct: 64  APAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPA 109


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 61/207 (29%), Positives = 85/207 (41%), Gaps = 23/207 (11%)

Query: 13  PPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYD 72
           PP  K   K+K   K     +  + P V+E   K V + +E S V     +K        
Sbjct: 577 PP--KVESKEKVMVKKDKPIKTETKPSVTE---KEVPSKEEPSPVKAEVAEK-------- 623

Query: 73  VEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKKAGGTKPKKPV 132
            +  + + K   +  V K T V+ +        K  K+ A  E K  +KK    K ++  
Sbjct: 624 -QATDVKPKAAKEKTVKKETKVKPEDKKEEKE-KPKKEVAKKEDKTPIKKEEKPKKEEVK 681

Query: 133 GAAKKPKKAAGGATPKKSAK-KTP----KKAKKPAAATVTKKVAKSPKKAKVAKPKKAAK 187
              KK  K      PKK  K +TP    KK  K       KK  K PKK     PK A K
Sbjct: 682 KEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKK 741

Query: 188 SA---AKAVKPKAAKPKVVKPKKAAPK 211
           S+   ++A KP A KPKV K +++  K
Sbjct: 742 SSTPLSEAKKPAALKPKVPKKEESVKK 768



 Score = 48.1 bits (113), Expect = 5e-06
 Identities = 61/210 (29%), Positives = 91/210 (43%), Gaps = 21/210 (10%)

Query: 19  PVKKKAAKKAGGTPRKASGPPVSELITKAVAA-SKERSG----VSLAALKKALAAAGYDV 73
           PV K+   K     R++  P    L +K+V   SKE +     V+       + +    +
Sbjct: 528 PVVKQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVM 587

Query: 74  EKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK------VKKAGGTK 127
            K +  IK   K  V++   V +K   +    ++ +K A+ + KPK      VKK    K
Sbjct: 588 VKKDKPIKTETKPSVTEKE-VPSKEEPSPVKAEVAEKQAT-DVKPKAAKEKTVKKETKVK 645

Query: 128 PKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVAKPKKAAK 187
           P+      +KPKK       KK  K   KK +KP    V K+V K  KK +  +PKK  K
Sbjct: 646 PEDKKEEKEKPKKEVA----KKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVK 701

Query: 188 SAA--KAVKPKAAKP--KVVKPKKAAPKKK 213
                K VK +  K   K VK ++  PKK+
Sbjct: 702 KETPPKEVKKEVKKEEKKEVKKEEKEPKKE 731



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 63/226 (27%), Positives = 81/226 (35%), Gaps = 36/226 (15%)

Query: 9   PAAAPPAEKAPVKK----KAAKKAGGT----PRKASGPPVSELITKAVAASKERSGVSLA 60
           P      EK  VKK    K   K   T    P K    PV     KA  A K+ + V   
Sbjct: 577 PPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPV-----KAEVAEKQATDVKPK 631

Query: 61  ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV 120
           A K+        V+  + + +   K    K    +   T      K  K+    E K ++
Sbjct: 632 AAKEKTVKKETKVKPEDKKEE---KEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEI 688

Query: 121 KKAGGTKPKKPVGAAKKPKKAAGGAT-------------PKKSAKKTPKKAKKPAAATVT 167
           KK    +PKK V     PK+                   PKK  KK PK AKK   ++  
Sbjct: 689 KKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKK---SSTP 745

Query: 168 KKVAKSPKKAKVAKPKK---AAKSAAKAVKPK-AAKPKVVKPKKAA 209
              AK P   K   PKK     K +  A KPK   K KV+K +  A
Sbjct: 746 LSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKA 791



 Score = 34.3 bits (77), Expect = 0.081
 Identities = 49/184 (26%), Positives = 63/184 (34%), Gaps = 16/184 (8%)

Query: 16  EKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAAS--KERSGVSLAALKKALAAAGYDV 73
           EK   KK+ AKK   TP K    P  E + K V     KE        +KK         
Sbjct: 652 EKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKK--------- 702

Query: 74  EKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKP--KVKKAGGTKPKKP 131
           E     +K  +K    K    + K        K   K A   + P  + KK    KPK P
Sbjct: 703 ETPPKEVKKEVKKEEKKEVKKEEKEP--KKEIKKLPKDAKKSSTPLSEAKKPAALKPKVP 760

Query: 132 VGAAKKPKKAAGGATPKKSAK-KTPKKAKKPAAATVTKKVAKSPKKAKVAKPKKAAKSAA 190
                  K +     PK+  K K  KK  K A A        +   A +A    AA   A
Sbjct: 761 KKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPA 820

Query: 191 KAVK 194
           K ++
Sbjct: 821 KELE 824



 Score = 29.6 bits (65), Expect = 2.0
 Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 2/72 (2%)

Query: 125  GTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKK-AKVAKPK 183
            G   KK +    K KK           KK+  K+K  AA+     + +S  K ++VA PK
Sbjct: 2232 GKALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPK 2291

Query: 184  KAAKSAAKAVKP 195
            K  +S  KA KP
Sbjct: 2292 KK-ESVEKAAKP 2302


>gi|56676330 HP1-BP74 [Homo sapiens]
          Length = 553

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 29/95 (30%), Positives = 54/95 (56%), Gaps = 3/95 (3%)

Query: 31  TPRKASG-PPVSELITKAVAASKERSGVSLAALKKALAAA--GYDVEKNNSRIKLGLKSL 87
           TP  +S  P +  ++T+A+ A  ++SG S+ A++K +       ++E+    +K  LK  
Sbjct: 151 TPMASSPRPKMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLKQALKRE 210

Query: 88  VSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKK 122
           +++G + Q KG GASGSF + +K+     K + +K
Sbjct: 211 LNRGVIKQVKGKGASGSFVVVQKSRKTPQKSRNRK 245



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 58/226 (25%), Positives = 79/226 (34%), Gaps = 45/226 (19%)

Query: 26  KKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSR--IKLG 83
           KK+G  P    G  +   I  A+AA  E    S  ALKK +         N     +K  
Sbjct: 329 KKSGEKPL-LGGSLMEYAILSAIAAMNEPKTCSTTALKKYVLENHPGTNSNYQMHLLKKT 387

Query: 84  LKSLVSKGTLVQTKGTGASGSFKL------------------------------NKKAAS 113
           L+     G + Q  G G SG+F+L                              +++ + 
Sbjct: 388 LQKCEKNGWMEQISGKGFSGTFQLCFPYYPSPGVLFPKKEPDDSRDEDEDEDESSEEDSE 447

Query: 114 GEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSA----------KKTPKKAKKPAA 163
            E  P  ++     P K  G A   K+      PK SA          KK P KAK PA 
Sbjct: 448 DEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAAQRGKARPLPKKAPPKAKTPAK 507

Query: 164 AT-VTKKVAKSPKKAKVAKPKKAAKSAAKAV-KPKAAKPKVVKPKK 207
            T  +  V K P      KP  +A+   K   K K+   K  + KK
Sbjct: 508 KTRPSSTVIKKPSGGSSKKPATSARKEVKLPGKGKSTMKKSFRVKK 553



 Score = 32.7 bits (73), Expect = 0.24
 Identities = 37/133 (27%), Positives = 55/133 (41%), Gaps = 12/133 (9%)

Query: 80  IKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKKAGGTKPK----KPVGAA 135
           +K  L+  V +G L Q  G GASG+F+L K   SGE KP +   GG+  +      + A 
Sbjct: 301 LKNALQRAVERGQLEQITGKGASGTFQLKK---SGE-KPLL---GGSLMEYAILSAIAAM 353

Query: 136 KKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVAK-PKKAAKSAAKAVK 194
            +PK  +  A  K   +  P          + K + K  K   + +   K      +   
Sbjct: 354 NEPKTCSTTALKKYVLENHPGTNSNYQMHLLKKTLQKCEKNGWMEQISGKGFSGTFQLCF 413

Query: 195 PKAAKPKVVKPKK 207
           P    P V+ PKK
Sbjct: 414 PYYPSPGVLFPKK 426


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 37/109 (33%), Positives = 47/109 (43%), Gaps = 16/109 (14%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKK------------AKKPA 162
           E  P   K+  T PK+P  A   PKK A   TPK+ A  TPK+             K+PA
Sbjct: 285 EPAPTTTKSAPTTPKEP--APTTPKKPAP-TTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 341

Query: 163 AATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAP 210
             T  +    +PKK     PK+ A +  K   P   K P    PK+ AP
Sbjct: 342 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 390



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 37/109 (33%), Positives = 46/109 (42%), Gaps = 11/109 (10%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKK-----PKKAAGGATPKKSAKKTPKK----AKKPAAAT 165
           E  P   K+  T PK+P     K     PK+ A   T K+ A  TPK+      K  A T
Sbjct: 231 EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA-PTTTKEPAPTTPKEPAPTTTKEPAPT 289

Query: 166 VTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAPKKK 213
            TK    +PK+     PKK A +  K   P   K P    PK+ AP  K
Sbjct: 290 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 338



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 36/108 (33%), Positives = 47/108 (43%), Gaps = 13/108 (12%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKK------PKKAAGGATPKKSAKKTPKKA-----KKPAA 163
           E  P   K+  T PK+P     K      PK+ A   TPKK A  TPK+      K+PA 
Sbjct: 402 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP-TTPKKPAPTTPKEPAPTTPKEPAP 460

Query: 164 ATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKA-AKPKVVKPKKAAP 210
            T  K    +PK+     PK+ A +  K + P    K     P+K AP
Sbjct: 461 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 508



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 55/216 (25%), Positives = 71/216 (32%), Gaps = 24/216 (11%)

Query: 4   TAPAAPAAAPPAEKAPVKKKAA------KKAGGTPRKASGPPVSELITKAVAASKERSGV 57
           T P  PA   P E AP   K        K A  TP K +     EL           +  
Sbjct: 469 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 528

Query: 58  SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 117
             A      AA     E   +  K    +   +      K T  +           G A 
Sbjct: 529 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT--------TPKGTAP 580

Query: 118 PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKA 177
             +K+   T PKKP      PK+ A    P  + + T     KPA  T       +PK+ 
Sbjct: 581 TTLKEPAPTTPKKPA-----PKELA----PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP 631

Query: 178 KVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAPKK 212
               PK+ A +  K   P   K P    PKK APK+
Sbjct: 632 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE 667



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 56/213 (26%), Positives = 71/213 (33%), Gaps = 16/213 (7%)

Query: 1   MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRK-ASGPPVSELITKAVAASKERSGVSL 59
           ++ T P  P    P E AP   KAA  A  TP++ A   P     T     +      + 
Sbjct: 514 LAPTTPEEPTPTTPEEPAPTTPKAA--APNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 571

Query: 60  AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK 119
               K  A          +  K   K L    T   T  T      K       G A   
Sbjct: 572 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT----CDKPAPTTPKGTAPTT 627

Query: 120 VKKAGGTKPKKPV-----GAAKKPKKAAGGATPKKSAKK--TPKKAKKPAAATVTKKVAK 172
            K+   T PK+P      G A    K     TPKK A K   P   K P + T  K    
Sbjct: 628 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 687

Query: 173 SPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKP 205
           +PK+     PK+ A +  K  KP    P+   P
Sbjct: 688 TPKETAPTTPKEPAPTTPK--KPAPTTPETPPP 718



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 33/96 (34%), Positives = 45/96 (46%), Gaps = 9/96 (9%)

Query: 121 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKK-----AKKPAAATVTKKVAKSPK 175
           K+   T PK+P  A   PKK A   TPK+ A  TPK+      KKPA  T  +    +PK
Sbjct: 424 KEPAPTTPKEP--APTTPKKPAP-TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 480

Query: 176 KAKVAKPKKAAKSAAKAVKPKA-AKPKVVKPKKAAP 210
           +     PKK   +  + + P    KP    P++ AP
Sbjct: 481 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 516



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 9/105 (8%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKK------PKKAAGGATPKKS---AKKTPKKAKKPAAAT 165
           E  P   K+  T PK+P     K      PK+ A   T + +    K  P   K+PA  T
Sbjct: 246 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 305

Query: 166 VTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
             K    +PK+     PK+   +  K   P   +P    PK+ AP
Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP 350



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 34/101 (33%), Positives = 46/101 (45%), Gaps = 9/101 (8%)

Query: 116 AKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKA-----KKPAAATVTKKV 170
           A    KK   T PK+P  A   PK+ A   TPKK    TP+K      +KPA  T  +  
Sbjct: 459 APTTTKKPAPTTPKEP--APTTPKETAP-TTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 515

Query: 171 AKSPKKAKVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAP 210
             +P++     P++ A +  KA  P   K P    PK+ AP
Sbjct: 516 PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 556



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 1/91 (1%)

Query: 121 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA 180
           KK   T PK+P     K         P  +  K P      +A T TK+ A +  K+   
Sbjct: 354 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 413

Query: 181 KPKKAAKSAAKAVKPKAAK-PKVVKPKKAAP 210
            PK+ + +  K   P   K P    PKK AP
Sbjct: 414 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 444



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 8/94 (8%)

Query: 121 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKA----KKPAAATVTKKVAKSPKK 176
           K+   T PK+P     K    +   TPK+ A  T K A    K+PA  T  +    +PK+
Sbjct: 222 KEPASTTPKEPTPTTIK----SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 277

Query: 177 AKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
                 K+ A +  K+      +P    PKK AP
Sbjct: 278 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP 311



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 29/99 (29%), Positives = 40/99 (40%), Gaps = 7/99 (7%)

Query: 116 AKPKVKKAGGTKPKKPVGAAKKPKKA----AGGATPKKSAKKTPKKAKKPAAATVTKKVA 171
           A    K+   T PK+P     K        +   TPK+ A  TP   KKPA  T  +   
Sbjct: 263 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP---KKPAPTTPKEPAP 319

Query: 172 KSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
            +PK+     PK+ A +  +       +P    PKK AP
Sbjct: 320 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 358



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 29/98 (29%), Positives = 40/98 (40%), Gaps = 8/98 (8%)

Query: 121 KKAGGTKPKKPVGAAKKP----KKAAGGATPKKSAKKTPKK----AKKPAAATVTKKVAK 172
           K+   T PK+P    K+P     K      PKK A  TPK+      K  A T TK+ + 
Sbjct: 323 KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 382

Query: 173 SPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
           +  K       K+A +  K   P   K     PK+ +P
Sbjct: 383 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 420



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 32/104 (30%), Positives = 41/104 (39%), Gaps = 9/104 (8%)

Query: 116 AKPKVKKAGGTKPKKPVGAAKKPKKAA---GGATPKKSAKKTPKK-----AKKPAAATVT 167
           A    K+   T PK+P     K           T  KSA  TPK+      K+PA  T  
Sbjct: 373 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 432

Query: 168 KKVAKSPKKAKVAKPKKAAKSAAKAVKPKAA-KPKVVKPKKAAP 210
           +    +PKK     PK+ A +  K   P    KP    PK+ AP
Sbjct: 433 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 476



 Score = 40.8 bits (94), Expect = 9e-04
 Identities = 31/101 (30%), Positives = 40/101 (39%), Gaps = 8/101 (7%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKKPK----KAAGGATPKKSAKKTPKKAKKPAAATVTKKV 170
           E  P   K+  T  K+P     K      K     T K+ A  TP   K+PA  T  K  
Sbjct: 387 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP---KEPAPTTPKKPA 443

Query: 171 AKSPKKAKVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAP 210
             +PK+     PK+ A +  K   P   K P    PK+ AP
Sbjct: 444 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP 484



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 52/215 (24%), Positives = 70/215 (32%), Gaps = 24/215 (11%)

Query: 2   SETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAA 61
           +ET    PA   P E  P   K  + A  TP++    P    I  A    KE +  +  +
Sbjct: 201 AETTTKGPALTTPKEPTPTTPK--EPASTTPKE----PTPTTIKSAPTTPKEPAPTTTKS 254

Query: 62  LKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVK 121
                        K  +           K     T    A  + K         A    K
Sbjct: 255 APTTPKEPAPTTTKEPA-------PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 307

Query: 122 KAGGTKPKKPVGAAKK------PKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPK 175
           K   T PK+P     K      PK+ A   T K+ A  TP   K+PA     K    +PK
Sbjct: 308 KPAPTTPKEPAPTTPKEPTPTTPKEPA--PTTKEPAPTTP---KEPAPTAPKKPAPTTPK 362

Query: 176 KAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
           +     PK+ A +  K   P   K       K+AP
Sbjct: 363 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 397



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 56/217 (25%), Positives = 73/217 (33%), Gaps = 15/217 (6%)

Query: 4   TAPAAPAAAPPAEKAPVK-KKAAKKAGGTPRKASGPPVSELITK---AVAASKERSGVSL 59
           T P   A   P E AP   KK A     TP   +    +   TK    +  S + S   L
Sbjct: 687 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 746

Query: 60  AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK 119
           +A     A      E      K    +     T  + K T       L     +  A PK
Sbjct: 747 SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD----LRTTPETTTAAPK 802

Query: 120 VKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKV 179
           + K   T  +K   +  K        T   +   TP K       T+  KV  + K    
Sbjct: 803 MTKETATTTEKTTES--KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITT 860

Query: 180 A----KPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKK 212
                KP++ AK   +A   KA  PK  KP K APKK
Sbjct: 861 TEIMNKPEETAKPKDRATNSKATTPKPQKPTK-APKK 896



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 50/219 (22%), Positives = 71/219 (32%), Gaps = 23/219 (10%)

Query: 14  PAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDV 73
           P  K PV  +A         K + P  S      V+ S + +       + +L     D 
Sbjct: 78  PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNS-DT 136

Query: 74  EKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLN--------KKAASGEAKPKVKKAGG 125
            K  S       ++ +K T    K T   G  K          +K ++ +  P  K    
Sbjct: 137 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 196

Query: 126 TKPKKPV---GAAKKPKKAAGGATPKKSAKKTPKK-----------AKKPAAATVTKKVA 171
             PK      G A    K     TPK+ A  TPK+             K  A T TK   
Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 256

Query: 172 KSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
            +PK+      K+ A +  K   P   K       K+AP
Sbjct: 257 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 295



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 30/101 (29%), Positives = 40/101 (39%), Gaps = 11/101 (10%)

Query: 121 KKAGGTKPKKPVGAAKKPK-----KAAGGATPKKSAKKTPKKA-----KKPAAATVTKKV 170
           KK   T PK+P     K       K     TPK+ A  TPK+      KK    T  K  
Sbjct: 440 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 499

Query: 171 AKSPKKAKVAKPKKAAKSAAKAVKPKA-AKPKVVKPKKAAP 210
             +P+K     P++ A +  +   P    +P    PK AAP
Sbjct: 500 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 540



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 56/241 (23%), Positives = 76/241 (31%), Gaps = 39/241 (16%)

Query: 1   MSETAPAAPAAAPPAEKAPVKKK-----AAKKAGGTPRKASGPPVSELITKAVAASKERS 55
           + E AP  P    P E AP   K        K   T  K + P   +    A    KE +
Sbjct: 583 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK--EPAPTTPKEPA 640

Query: 56  GVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGE 115
             +     K  A          +  K   K L        TKG  ++ S K         
Sbjct: 641 PTT----PKGTAPTTLKEPAPTTPKKPAPKELAP----TTTKGPTSTTSDKPAPTTPKET 692

Query: 116 AKPKVKKAGGTKPKKPV-----------------GAAKKP---KKAAGGATPKKSAKKTP 155
           A    K+   T PKKP                     K+P    K+   +TP+ SA+ TP
Sbjct: 693 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTP 752

Query: 156 K----KAKKPAAATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPK 211
           K      K+P   T     A  P+    AK K   +      +   A PK+ K      +
Sbjct: 753 KALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTE 812

Query: 212 K 212
           K
Sbjct: 813 K 813



 Score = 31.6 bits (70), Expect = 0.52
 Identities = 43/182 (23%), Positives = 61/182 (33%), Gaps = 22/182 (12%)

Query: 2   SETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAA 61
           S   P  P    PA   P     AK    T R     P  E  T A   +KE +  +   
Sbjct: 758 SPKEPGVPTTKTPAATKPEMTTTAKDKT-TERDLRTTP--ETTTAAPKMTKETATTTEKT 814

Query: 62  LKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFK----LNKKAASGEAK 117
            +  + A    V    ++     K    K T +  K T    +      +NK   + + K
Sbjct: 815 TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPK 874

Query: 118 PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKA 177
            +   +  T PK      +KP KA     PKK     P   KKP      +K   +P   
Sbjct: 875 DRATNSKATTPKP-----QKPTKA-----PKK-----PTSTKKPKTMPRVRKPKTTPTPR 919

Query: 178 KV 179
           K+
Sbjct: 920 KM 921



 Score = 31.2 bits (69), Expect = 0.68
 Identities = 52/217 (23%), Positives = 72/217 (33%), Gaps = 19/217 (8%)

Query: 5   APAAPAAAPPAEK---APVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSL-- 59
           AP  P   PP       P   K       +P +++    +E   KA+  S +  GV    
Sbjct: 709 APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTK 768

Query: 60  --AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 117
             AA K  +     D  K   R  L      +      TK T  +       K  +   +
Sbjct: 769 TPAATKPEMTTTAKD--KTTER-DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 825

Query: 118 PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKT-----PKKAKKPAAATVTKKVAK 172
                   T P K +   K    A    T KK+   T     P++  KP       K A 
Sbjct: 826 VTSTTTQDTTPFK-ITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSK-AT 883

Query: 173 SPKKAKVAK-PKKAAKSAAKAVKPKAAKPKVV-KPKK 207
           +PK  K  K PKK   +      P+  KPK    P+K
Sbjct: 884 TPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 920


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 37/109 (33%), Positives = 47/109 (43%), Gaps = 16/109 (14%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKK------------AKKPA 162
           E  P   K+  T PK+P  A   PKK A   TPK+ A  TPK+             K+PA
Sbjct: 326 EPAPTTTKSAPTTPKEP--APTTPKKPAP-TTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 382

Query: 163 AATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAP 210
             T  +    +PKK     PK+ A +  K   P   K P    PK+ AP
Sbjct: 383 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 431



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 37/109 (33%), Positives = 46/109 (42%), Gaps = 11/109 (10%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKK-----PKKAAGGATPKKSAKKTPKK----AKKPAAAT 165
           E  P   K+  T PK+P     K     PK+ A   T K+ A  TPK+      K  A T
Sbjct: 272 EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA-PTTTKEPAPTTPKEPAPTTTKEPAPT 330

Query: 166 VTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAPKKK 213
            TK    +PK+     PKK A +  K   P   K P    PK+ AP  K
Sbjct: 331 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 379



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 36/108 (33%), Positives = 47/108 (43%), Gaps = 13/108 (12%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKK------PKKAAGGATPKKSAKKTPKKA-----KKPAA 163
           E  P   K+  T PK+P     K      PK+ A   TPKK A  TPK+      K+PA 
Sbjct: 443 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP-TTPKKPAPTTPKEPAPTTPKEPAP 501

Query: 164 ATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKA-AKPKVVKPKKAAP 210
            T  K    +PK+     PK+ A +  K + P    K     P+K AP
Sbjct: 502 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 549



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 55/216 (25%), Positives = 71/216 (32%), Gaps = 24/216 (11%)

Query: 4   TAPAAPAAAPPAEKAPVKKKAA------KKAGGTPRKASGPPVSELITKAVAASKERSGV 57
           T P  PA   P E AP   K        K A  TP K +     EL           +  
Sbjct: 510 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 569

Query: 58  SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 117
             A      AA     E   +  K    +   +      K T  +           G A 
Sbjct: 570 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT--------TPKGTAP 621

Query: 118 PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKA 177
             +K+   T PKKP      PK+ A    P  + + T     KPA  T       +PK+ 
Sbjct: 622 TTLKEPAPTTPKKPA-----PKELA----PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP 672

Query: 178 KVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAPKK 212
               PK+ A +  K   P   K P    PKK APK+
Sbjct: 673 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE 708



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 56/213 (26%), Positives = 71/213 (33%), Gaps = 16/213 (7%)

Query: 1   MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRK-ASGPPVSELITKAVAASKERSGVSL 59
           ++ T P  P    P E AP   KAA  A  TP++ A   P     T     +      + 
Sbjct: 555 LAPTTPEEPTPTTPEEPAPTTPKAA--APNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 612

Query: 60  AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK 119
               K  A          +  K   K L    T   T  T      K       G A   
Sbjct: 613 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT----CDKPAPTTPKGTAPTT 668

Query: 120 VKKAGGTKPKKPV-----GAAKKPKKAAGGATPKKSAKK--TPKKAKKPAAATVTKKVAK 172
            K+   T PK+P      G A    K     TPKK A K   P   K P + T  K    
Sbjct: 669 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 728

Query: 173 SPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKP 205
           +PK+     PK+ A +  K  KP    P+   P
Sbjct: 729 TPKETAPTTPKEPAPTTPK--KPAPTTPETPPP 759



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 33/96 (34%), Positives = 45/96 (46%), Gaps = 9/96 (9%)

Query: 121 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKK-----AKKPAAATVTKKVAKSPK 175
           K+   T PK+P  A   PKK A   TPK+ A  TPK+      KKPA  T  +    +PK
Sbjct: 465 KEPAPTTPKEP--APTTPKKPAP-TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 521

Query: 176 KAKVAKPKKAAKSAAKAVKPKA-AKPKVVKPKKAAP 210
           +     PKK   +  + + P    KP    P++ AP
Sbjct: 522 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 557



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 9/105 (8%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKK------PKKAAGGATPKKS---AKKTPKKAKKPAAAT 165
           E  P   K+  T PK+P     K      PK+ A   T + +    K  P   K+PA  T
Sbjct: 287 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 346

Query: 166 VTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
             K    +PK+     PK+   +  K   P   +P    PK+ AP
Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP 391



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 34/101 (33%), Positives = 46/101 (45%), Gaps = 9/101 (8%)

Query: 116 AKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKA-----KKPAAATVTKKV 170
           A    KK   T PK+P  A   PK+ A   TPKK    TP+K      +KPA  T  +  
Sbjct: 500 APTTTKKPAPTTPKEP--APTTPKETAP-TTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 556

Query: 171 AKSPKKAKVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAP 210
             +P++     P++ A +  KA  P   K P    PK+ AP
Sbjct: 557 PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 597



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 1/91 (1%)

Query: 121 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA 180
           KK   T PK+P     K         P  +  K P      +A T TK+ A +  K+   
Sbjct: 395 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 454

Query: 181 KPKKAAKSAAKAVKPKAAK-PKVVKPKKAAP 210
            PK+ + +  K   P   K P    PKK AP
Sbjct: 455 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 485



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 8/94 (8%)

Query: 121 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKA----KKPAAATVTKKVAKSPKK 176
           K+   T PK+P     K    +   TPK+ A  T K A    K+PA  T  +    +PK+
Sbjct: 263 KEPASTTPKEPTPTTIK----SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 318

Query: 177 AKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
                 K+ A +  K+      +P    PKK AP
Sbjct: 319 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP 352



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 29/99 (29%), Positives = 40/99 (40%), Gaps = 7/99 (7%)

Query: 116 AKPKVKKAGGTKPKKPVGAAKKPKKA----AGGATPKKSAKKTPKKAKKPAAATVTKKVA 171
           A    K+   T PK+P     K        +   TPK+ A  TP   KKPA  T  +   
Sbjct: 304 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP---KKPAPTTPKEPAP 360

Query: 172 KSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
            +PK+     PK+ A +  +       +P    PKK AP
Sbjct: 361 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 399



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 29/98 (29%), Positives = 40/98 (40%), Gaps = 8/98 (8%)

Query: 121 KKAGGTKPKKPVGAAKKP----KKAAGGATPKKSAKKTPKK----AKKPAAATVTKKVAK 172
           K+   T PK+P    K+P     K      PKK A  TPK+      K  A T TK+ + 
Sbjct: 364 KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 423

Query: 173 SPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
           +  K       K+A +  K   P   K     PK+ +P
Sbjct: 424 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 461



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 32/104 (30%), Positives = 41/104 (39%), Gaps = 9/104 (8%)

Query: 116 AKPKVKKAGGTKPKKPVGAAKKPKKAA---GGATPKKSAKKTPKK-----AKKPAAATVT 167
           A    K+   T PK+P     K           T  KSA  TPK+      K+PA  T  
Sbjct: 414 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 473

Query: 168 KKVAKSPKKAKVAKPKKAAKSAAKAVKPKAA-KPKVVKPKKAAP 210
           +    +PKK     PK+ A +  K   P    KP    PK+ AP
Sbjct: 474 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 517



 Score = 40.8 bits (94), Expect = 9e-04
 Identities = 31/101 (30%), Positives = 40/101 (39%), Gaps = 8/101 (7%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKKPK----KAAGGATPKKSAKKTPKKAKKPAAATVTKKV 170
           E  P   K+  T  K+P     K      K     T K+ A  TP   K+PA  T  K  
Sbjct: 428 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP---KEPAPTTPKKPA 484

Query: 171 AKSPKKAKVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAP 210
             +PK+     PK+ A +  K   P   K P    PK+ AP
Sbjct: 485 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP 525



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 52/215 (24%), Positives = 70/215 (32%), Gaps = 24/215 (11%)

Query: 2   SETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAA 61
           +ET    PA   P E  P   K  + A  TP++    P    I  A    KE +  +  +
Sbjct: 242 AETTTKGPALTTPKEPTPTTPK--EPASTTPKE----PTPTTIKSAPTTPKEPAPTTTKS 295

Query: 62  LKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVK 121
                        K  +           K     T    A  + K         A    K
Sbjct: 296 APTTPKEPAPTTTKEPA-------PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 348

Query: 122 KAGGTKPKKPVGAAKK------PKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPK 175
           K   T PK+P     K      PK+ A   T K+ A  TP   K+PA     K    +PK
Sbjct: 349 KPAPTTPKEPAPTTPKEPTPTTPKEPA--PTTKEPAPTTP---KEPAPTAPKKPAPTTPK 403

Query: 176 KAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
           +     PK+ A +  K   P   K       K+AP
Sbjct: 404 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 438



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 56/217 (25%), Positives = 73/217 (33%), Gaps = 15/217 (6%)

Query: 4   TAPAAPAAAPPAEKAPVK-KKAAKKAGGTPRKASGPPVSELITK---AVAASKERSGVSL 59
           T P   A   P E AP   KK A     TP   +    +   TK    +  S + S   L
Sbjct: 728 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 787

Query: 60  AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK 119
           +A     A      E      K    +     T  + K T       L     +  A PK
Sbjct: 788 SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD----LRTTPETTTAAPK 843

Query: 120 VKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKV 179
           + K   T  +K   +  K        T   +   TP K       T+  KV  + K    
Sbjct: 844 MTKETATTTEKTTES--KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITT 901

Query: 180 A----KPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKK 212
                KP++ AK   +A   KA  PK  KP K APKK
Sbjct: 902 TEIMNKPEETAKPKDRATNSKATTPKPQKPTK-APKK 937



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 50/219 (22%), Positives = 71/219 (32%), Gaps = 23/219 (10%)

Query: 14  PAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDV 73
           P  K PV  +A         K + P  S      V+ S + +       + +L     D 
Sbjct: 119 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNS-DT 177

Query: 74  EKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLN--------KKAASGEAKPKVKKAGG 125
            K  S       ++ +K T    K T   G  K          +K ++ +  P  K    
Sbjct: 178 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 237

Query: 126 TKPKKPV---GAAKKPKKAAGGATPKKSAKKTPKK-----------AKKPAAATVTKKVA 171
             PK      G A    K     TPK+ A  TPK+             K  A T TK   
Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 297

Query: 172 KSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
            +PK+      K+ A +  K   P   K       K+AP
Sbjct: 298 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 336



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 30/101 (29%), Positives = 40/101 (39%), Gaps = 11/101 (10%)

Query: 121 KKAGGTKPKKPVGAAKKPK-----KAAGGATPKKSAKKTPKKA-----KKPAAATVTKKV 170
           KK   T PK+P     K       K     TPK+ A  TPK+      KK    T  K  
Sbjct: 481 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 540

Query: 171 AKSPKKAKVAKPKKAAKSAAKAVKPKA-AKPKVVKPKKAAP 210
             +P+K     P++ A +  +   P    +P    PK AAP
Sbjct: 541 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 581



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 56/241 (23%), Positives = 76/241 (31%), Gaps = 39/241 (16%)

Query: 1   MSETAPAAPAAAPPAEKAPVKKK-----AAKKAGGTPRKASGPPVSELITKAVAASKERS 55
           + E AP  P    P E AP   K        K   T  K + P   +    A    KE +
Sbjct: 624 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK--EPAPTTPKEPA 681

Query: 56  GVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGE 115
             +     K  A          +  K   K L        TKG  ++ S K         
Sbjct: 682 PTT----PKGTAPTTLKEPAPTTPKKPAPKELAP----TTTKGPTSTTSDKPAPTTPKET 733

Query: 116 AKPKVKKAGGTKPKKPV-----------------GAAKKP---KKAAGGATPKKSAKKTP 155
           A    K+   T PKKP                     K+P    K+   +TP+ SA+ TP
Sbjct: 734 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTP 793

Query: 156 K----KAKKPAAATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPK 211
           K      K+P   T     A  P+    AK K   +      +   A PK+ K      +
Sbjct: 794 KALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTE 853

Query: 212 K 212
           K
Sbjct: 854 K 854



 Score = 31.6 bits (70), Expect = 0.52
 Identities = 43/182 (23%), Positives = 61/182 (33%), Gaps = 22/182 (12%)

Query: 2   SETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAA 61
           S   P  P    PA   P     AK    T R     P  E  T A   +KE +  +   
Sbjct: 799 SPKEPGVPTTKTPAATKPEMTTTAKDKT-TERDLRTTP--ETTTAAPKMTKETATTTEKT 855

Query: 62  LKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFK----LNKKAASGEAK 117
            +  + A    V    ++     K    K T +  K T    +      +NK   + + K
Sbjct: 856 TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPK 915

Query: 118 PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKA 177
            +   +  T PK      +KP KA     PKK     P   KKP      +K   +P   
Sbjct: 916 DRATNSKATTPKP-----QKPTKA-----PKK-----PTSTKKPKTMPRVRKPKTTPTPR 960

Query: 178 KV 179
           K+
Sbjct: 961 KM 962



 Score = 31.2 bits (69), Expect = 0.68
 Identities = 52/217 (23%), Positives = 72/217 (33%), Gaps = 19/217 (8%)

Query: 5   APAAPAAAPPAEK---APVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSL-- 59
           AP  P   PP       P   K       +P +++    +E   KA+  S +  GV    
Sbjct: 750 APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTK 809

Query: 60  --AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 117
             AA K  +     D  K   R  L      +      TK T  +       K  +   +
Sbjct: 810 TPAATKPEMTTTAKD--KTTER-DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 866

Query: 118 PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKT-----PKKAKKPAAATVTKKVAK 172
                   T P K +   K    A    T KK+   T     P++  KP       K A 
Sbjct: 867 VTSTTTQDTTPFK-ITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSK-AT 924

Query: 173 SPKKAKVAK-PKKAAKSAAKAVKPKAAKPKVV-KPKK 207
           +PK  K  K PKK   +      P+  KPK    P+K
Sbjct: 925 TPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 961


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 37/109 (33%), Positives = 47/109 (43%), Gaps = 16/109 (14%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKK------------AKKPA 162
           E  P   K+  T PK+P  A   PKK A   TPK+ A  TPK+             K+PA
Sbjct: 378 EPAPTTTKSAPTTPKEP--APTTPKKPAP-TTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 434

Query: 163 AATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAP 210
             T  +    +PKK     PK+ A +  K   P   K P    PK+ AP
Sbjct: 435 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 483



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 37/109 (33%), Positives = 46/109 (42%), Gaps = 11/109 (10%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKK-----PKKAAGGATPKKSAKKTPKK----AKKPAAAT 165
           E  P   K+  T PK+P     K     PK+ A   T K+ A  TPK+      K  A T
Sbjct: 324 EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA-PTTTKEPAPTTPKEPAPTTTKEPAPT 382

Query: 166 VTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAPKKK 213
            TK    +PK+     PKK A +  K   P   K P    PK+ AP  K
Sbjct: 383 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 431



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 36/108 (33%), Positives = 47/108 (43%), Gaps = 13/108 (12%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKK------PKKAAGGATPKKSAKKTPKKA-----KKPAA 163
           E  P   K+  T PK+P     K      PK+ A   TPKK A  TPK+      K+PA 
Sbjct: 495 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP-TTPKKPAPTTPKEPAPTTPKEPAP 553

Query: 164 ATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKA-AKPKVVKPKKAAP 210
            T  K    +PK+     PK+ A +  K + P    K     P+K AP
Sbjct: 554 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 601



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 55/216 (25%), Positives = 71/216 (32%), Gaps = 24/216 (11%)

Query: 4   TAPAAPAAAPPAEKAPVKKKAA------KKAGGTPRKASGPPVSELITKAVAASKERSGV 57
           T P  PA   P E AP   K        K A  TP K +     EL           +  
Sbjct: 562 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 621

Query: 58  SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 117
             A      AA     E   +  K    +   +      K T  +           G A 
Sbjct: 622 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT--------TPKGTAP 673

Query: 118 PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKA 177
             +K+   T PKKP      PK+ A    P  + + T     KPA  T       +PK+ 
Sbjct: 674 TTLKEPAPTTPKKPA-----PKELA----PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP 724

Query: 178 KVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAPKK 212
               PK+ A +  K   P   K P    PKK APK+
Sbjct: 725 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE 760



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 56/213 (26%), Positives = 71/213 (33%), Gaps = 16/213 (7%)

Query: 1   MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRK-ASGPPVSELITKAVAASKERSGVSL 59
           ++ T P  P    P E AP   KAA  A  TP++ A   P     T     +      + 
Sbjct: 607 LAPTTPEEPTPTTPEEPAPTTPKAA--APNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 664

Query: 60  AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK 119
               K  A          +  K   K L    T   T  T      K       G A   
Sbjct: 665 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT----CDKPAPTTPKGTAPTT 720

Query: 120 VKKAGGTKPKKPV-----GAAKKPKKAAGGATPKKSAKK--TPKKAKKPAAATVTKKVAK 172
            K+   T PK+P      G A    K     TPKK A K   P   K P + T  K    
Sbjct: 721 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 780

Query: 173 SPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKP 205
           +PK+     PK+ A +  K  KP    P+   P
Sbjct: 781 TPKETAPTTPKEPAPTTPK--KPAPTTPETPPP 811



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 33/96 (34%), Positives = 45/96 (46%), Gaps = 9/96 (9%)

Query: 121 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKK-----AKKPAAATVTKKVAKSPK 175
           K+   T PK+P  A   PKK A   TPK+ A  TPK+      KKPA  T  +    +PK
Sbjct: 517 KEPAPTTPKEP--APTTPKKPAP-TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 573

Query: 176 KAKVAKPKKAAKSAAKAVKPKA-AKPKVVKPKKAAP 210
           +     PKK   +  + + P    KP    P++ AP
Sbjct: 574 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 609



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 9/105 (8%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKK------PKKAAGGATPKKS---AKKTPKKAKKPAAAT 165
           E  P   K+  T PK+P     K      PK+ A   T + +    K  P   K+PA  T
Sbjct: 339 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 398

Query: 166 VTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
             K    +PK+     PK+   +  K   P   +P    PK+ AP
Sbjct: 399 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP 443



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 34/101 (33%), Positives = 46/101 (45%), Gaps = 9/101 (8%)

Query: 116 AKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKA-----KKPAAATVTKKV 170
           A    KK   T PK+P  A   PK+ A   TPKK    TP+K      +KPA  T  +  
Sbjct: 552 APTTTKKPAPTTPKEP--APTTPKETAP-TTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 608

Query: 171 AKSPKKAKVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAP 210
             +P++     P++ A +  KA  P   K P    PK+ AP
Sbjct: 609 PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 649



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 1/91 (1%)

Query: 121 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA 180
           KK   T PK+P     K         P  +  K P      +A T TK+ A +  K+   
Sbjct: 447 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 506

Query: 181 KPKKAAKSAAKAVKPKAAK-PKVVKPKKAAP 210
            PK+ + +  K   P   K P    PKK AP
Sbjct: 507 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 537



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 8/94 (8%)

Query: 121 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKA----KKPAAATVTKKVAKSPKK 176
           K+   T PK+P     K    +   TPK+ A  T K A    K+PA  T  +    +PK+
Sbjct: 315 KEPASTTPKEPTPTTIK----SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 370

Query: 177 AKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
                 K+ A +  K+      +P    PKK AP
Sbjct: 371 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP 404



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 29/99 (29%), Positives = 40/99 (40%), Gaps = 7/99 (7%)

Query: 116 AKPKVKKAGGTKPKKPVGAAKKPKKA----AGGATPKKSAKKTPKKAKKPAAATVTKKVA 171
           A    K+   T PK+P     K        +   TPK+ A  TP   KKPA  T  +   
Sbjct: 356 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP---KKPAPTTPKEPAP 412

Query: 172 KSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
            +PK+     PK+ A +  +       +P    PKK AP
Sbjct: 413 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 451



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 29/98 (29%), Positives = 40/98 (40%), Gaps = 8/98 (8%)

Query: 121 KKAGGTKPKKPVGAAKKP----KKAAGGATPKKSAKKTPKK----AKKPAAATVTKKVAK 172
           K+   T PK+P    K+P     K      PKK A  TPK+      K  A T TK+ + 
Sbjct: 416 KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 475

Query: 173 SPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
           +  K       K+A +  K   P   K     PK+ +P
Sbjct: 476 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 513



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 32/104 (30%), Positives = 41/104 (39%), Gaps = 9/104 (8%)

Query: 116 AKPKVKKAGGTKPKKPVGAAKKPKKAA---GGATPKKSAKKTPKK-----AKKPAAATVT 167
           A    K+   T PK+P     K           T  KSA  TPK+      K+PA  T  
Sbjct: 466 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 525

Query: 168 KKVAKSPKKAKVAKPKKAAKSAAKAVKPKAA-KPKVVKPKKAAP 210
           +    +PKK     PK+ A +  K   P    KP    PK+ AP
Sbjct: 526 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 569



 Score = 40.8 bits (94), Expect = 9e-04
 Identities = 31/101 (30%), Positives = 40/101 (39%), Gaps = 8/101 (7%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKKPK----KAAGGATPKKSAKKTPKKAKKPAAATVTKKV 170
           E  P   K+  T  K+P     K      K     T K+ A  TP   K+PA  T  K  
Sbjct: 480 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP---KEPAPTTPKKPA 536

Query: 171 AKSPKKAKVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAP 210
             +PK+     PK+ A +  K   P   K P    PK+ AP
Sbjct: 537 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP 577



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 52/215 (24%), Positives = 70/215 (32%), Gaps = 24/215 (11%)

Query: 2   SETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAA 61
           +ET    PA   P E  P   K  + A  TP++    P    I  A    KE +  +  +
Sbjct: 294 AETTTKGPALTTPKEPTPTTPK--EPASTTPKE----PTPTTIKSAPTTPKEPAPTTTKS 347

Query: 62  LKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVK 121
                        K  +           K     T    A  + K         A    K
Sbjct: 348 APTTPKEPAPTTTKEPA-------PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 400

Query: 122 KAGGTKPKKPVGAAKK------PKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPK 175
           K   T PK+P     K      PK+ A   T K+ A  TP   K+PA     K    +PK
Sbjct: 401 KPAPTTPKEPAPTTPKEPTPTTPKEPA--PTTKEPAPTTP---KEPAPTAPKKPAPTTPK 455

Query: 176 KAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
           +     PK+ A +  K   P   K       K+AP
Sbjct: 456 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 490



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 56/217 (25%), Positives = 73/217 (33%), Gaps = 15/217 (6%)

Query: 4   TAPAAPAAAPPAEKAPVK-KKAAKKAGGTPRKASGPPVSELITK---AVAASKERSGVSL 59
           T P   A   P E AP   KK A     TP   +    +   TK    +  S + S   L
Sbjct: 780 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 839

Query: 60  AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK 119
           +A     A      E      K    +     T  + K T       L     +  A PK
Sbjct: 840 SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD----LRTTPETTTAAPK 895

Query: 120 VKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKV 179
           + K   T  +K   +  K        T   +   TP K       T+  KV  + K    
Sbjct: 896 MTKETATTTEKTTES--KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITT 953

Query: 180 A----KPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKK 212
                KP++ AK   +A   KA  PK  KP K APKK
Sbjct: 954 TEIMNKPEETAKPKDRATNSKATTPKPQKPTK-APKK 989



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 50/219 (22%), Positives = 71/219 (32%), Gaps = 23/219 (10%)

Query: 14  PAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDV 73
           P  K PV  +A         K + P  S      V+ S + +       + +L     D 
Sbjct: 171 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNS-DT 229

Query: 74  EKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLN--------KKAASGEAKPKVKKAGG 125
            K  S       ++ +K T    K T   G  K          +K ++ +  P  K    
Sbjct: 230 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 289

Query: 126 TKPKKPV---GAAKKPKKAAGGATPKKSAKKTPKK-----------AKKPAAATVTKKVA 171
             PK      G A    K     TPK+ A  TPK+             K  A T TK   
Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 349

Query: 172 KSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
            +PK+      K+ A +  K   P   K       K+AP
Sbjct: 350 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 388



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 30/101 (29%), Positives = 40/101 (39%), Gaps = 11/101 (10%)

Query: 121 KKAGGTKPKKPVGAAKKPK-----KAAGGATPKKSAKKTPKKA-----KKPAAATVTKKV 170
           KK   T PK+P     K       K     TPK+ A  TPK+      KK    T  K  
Sbjct: 533 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 592

Query: 171 AKSPKKAKVAKPKKAAKSAAKAVKPKA-AKPKVVKPKKAAP 210
             +P+K     P++ A +  +   P    +P    PK AAP
Sbjct: 593 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 633



 Score = 34.7 bits (78), Expect = 0.062
 Identities = 48/229 (20%), Positives = 86/229 (37%), Gaps = 30/229 (13%)

Query: 9   PAAAPPAEKAPVKKKAAKKAGGTPRKASGPP-------------------VSELITKAVA 49
           P + P ++KAP    A++    T +++  PP                   VSE    + +
Sbjct: 69  PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 128

Query: 50  ASKERSGVSLAALKKAL-AAAGYDVEK----NNSRIKLGLKSLVSKGTLVQTKGTGA-SG 103
           +S   S  ++  +K +  +AA  +++K     +++     K    K  +V   G+G  +G
Sbjct: 129 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNG 188

Query: 104 SFKLNKKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAK-KPA 162
            FK+     S     KV  +      KP+    +P       T K+++    K+   +  
Sbjct: 189 DFKVTTPDTSTTQHNKVSTSPKITTAKPIN--PRPSLPPNSDTSKETSLTVNKETTVETK 246

Query: 163 AATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPK 211
             T T K   +  K K    K+       + K  A   KV+   K  PK
Sbjct: 247 ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL--AKPTPK 293



 Score = 33.5 bits (75), Expect = 0.14
 Identities = 52/226 (23%), Positives = 75/226 (33%), Gaps = 25/226 (11%)

Query: 4   TAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALK 63
           T P  PA   P E AP   K    A  T ++ +     +   K +A +  +   S    K
Sbjct: 650 TTPKEPAPTTPKETAPTTPKGT--APTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 707

Query: 64  KALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKKA 123
            A               K    +   +      KGT  +    L + A +   KP  K+ 
Sbjct: 708 PAPTTPKGTAPTTP---KEPAPTTPKEPAPTTPKGTAPT---TLKEPAPTTPKKPAPKEL 761

Query: 124 GGTKPKKPVG------AAKKPKKAA-------GGATPKKSAKKTPKKAKKPAAATVTKKV 170
             T  K P        A   PK+ A          TPKK A  TP+      +   T   
Sbjct: 762 APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTT 821

Query: 171 AKSP----KKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKK 212
            K P    K    + P+ +A+   KA++    +P V   K  A  K
Sbjct: 822 TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 867



 Score = 31.6 bits (70), Expect = 0.52
 Identities = 43/182 (23%), Positives = 61/182 (33%), Gaps = 22/182 (12%)

Query: 2    SETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAA 61
            S   P  P    PA   P     AK    T R     P  E  T A   +KE +  +   
Sbjct: 851  SPKEPGVPTTKTPAATKPEMTTTAKDKT-TERDLRTTP--ETTTAAPKMTKETATTTEKT 907

Query: 62   LKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFK----LNKKAASGEAK 117
             +  + A    V    ++     K    K T +  K T    +      +NK   + + K
Sbjct: 908  TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPK 967

Query: 118  PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKA 177
             +   +  T PK      +KP KA     PKK     P   KKP      +K   +P   
Sbjct: 968  DRATNSKATTPKP-----QKPTKA-----PKK-----PTSTKKPKTMPRVRKPKTTPTPR 1012

Query: 178  KV 179
            K+
Sbjct: 1013 KM 1014



 Score = 31.2 bits (69), Expect = 0.68
 Identities = 52/217 (23%), Positives = 72/217 (33%), Gaps = 19/217 (8%)

Query: 5    APAAPAAAPPAEK---APVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSL-- 59
            AP  P   PP       P   K       +P +++    +E   KA+  S +  GV    
Sbjct: 802  APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTK 861

Query: 60   --AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 117
              AA K  +     D  K   R  L      +      TK T  +       K  +   +
Sbjct: 862  TPAATKPEMTTTAKD--KTTER-DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 918

Query: 118  PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKT-----PKKAKKPAAATVTKKVAK 172
                    T P K +   K    A    T KK+   T     P++  KP       K A 
Sbjct: 919  VTSTTTQDTTPFK-ITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSK-AT 976

Query: 173  SPKKAKVAK-PKKAAKSAAKAVKPKAAKPKVV-KPKK 207
            +PK  K  K PKK   +      P+  KPK    P+K
Sbjct: 977  TPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 1013



 Score = 28.5 bits (62), Expect = 4.4
 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 18/100 (18%)

Query: 128 PKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKS---PKKAKVAKPKK 184
           P  P  + K P  +    T K + K++PK   K      TKKV +S    ++  V++ ++
Sbjct: 69  PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKK----TKKVIESEEITEEHSVSENQE 124

Query: 185 AAKSAA-----------KAVKPKAAKPKVVKPKKAAPKKK 213
           ++ S++           K+ K  AA  ++ K  K    KK
Sbjct: 125 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKK 164


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 37/109 (33%), Positives = 47/109 (43%), Gaps = 16/109 (14%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKK------------AKKPA 162
           E  P   K+  T PK+P  A   PKK A   TPK+ A  TPK+             K+PA
Sbjct: 419 EPAPTTTKSAPTTPKEP--APTTPKKPAP-TTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 475

Query: 163 AATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAP 210
             T  +    +PKK     PK+ A +  K   P   K P    PK+ AP
Sbjct: 476 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 524



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 37/109 (33%), Positives = 46/109 (42%), Gaps = 11/109 (10%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKK-----PKKAAGGATPKKSAKKTPKK----AKKPAAAT 165
           E  P   K+  T PK+P     K     PK+ A   T K+ A  TPK+      K  A T
Sbjct: 365 EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA-PTTTKEPAPTTPKEPAPTTTKEPAPT 423

Query: 166 VTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAPKKK 213
            TK    +PK+     PKK A +  K   P   K P    PK+ AP  K
Sbjct: 424 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 472



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 36/108 (33%), Positives = 47/108 (43%), Gaps = 13/108 (12%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKK------PKKAAGGATPKKSAKKTPKKA-----KKPAA 163
           E  P   K+  T PK+P     K      PK+ A   TPKK A  TPK+      K+PA 
Sbjct: 536 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP-TTPKKPAPTTPKEPAPTTPKEPAP 594

Query: 164 ATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKA-AKPKVVKPKKAAP 210
            T  K    +PK+     PK+ A +  K + P    K     P+K AP
Sbjct: 595 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 642



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 55/216 (25%), Positives = 71/216 (32%), Gaps = 24/216 (11%)

Query: 4   TAPAAPAAAPPAEKAPVKKKAA------KKAGGTPRKASGPPVSELITKAVAASKERSGV 57
           T P  PA   P E AP   K        K A  TP K +     EL           +  
Sbjct: 603 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 662

Query: 58  SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 117
             A      AA     E   +  K    +   +      K T  +           G A 
Sbjct: 663 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT--------TPKGTAP 714

Query: 118 PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKA 177
             +K+   T PKKP      PK+ A    P  + + T     KPA  T       +PK+ 
Sbjct: 715 TTLKEPAPTTPKKPA-----PKELA----PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP 765

Query: 178 KVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAPKK 212
               PK+ A +  K   P   K P    PKK APK+
Sbjct: 766 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE 801



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 56/213 (26%), Positives = 71/213 (33%), Gaps = 16/213 (7%)

Query: 1   MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRK-ASGPPVSELITKAVAASKERSGVSL 59
           ++ T P  P    P E AP   KAA  A  TP++ A   P     T     +      + 
Sbjct: 648 LAPTTPEEPTPTTPEEPAPTTPKAA--APNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 705

Query: 60  AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK 119
               K  A          +  K   K L    T   T  T      K       G A   
Sbjct: 706 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT----CDKPAPTTPKGTAPTT 761

Query: 120 VKKAGGTKPKKPV-----GAAKKPKKAAGGATPKKSAKK--TPKKAKKPAAATVTKKVAK 172
            K+   T PK+P      G A    K     TPKK A K   P   K P + T  K    
Sbjct: 762 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 821

Query: 173 SPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKP 205
           +PK+     PK+ A +  K  KP    P+   P
Sbjct: 822 TPKETAPTTPKEPAPTTPK--KPAPTTPETPPP 852



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 33/96 (34%), Positives = 45/96 (46%), Gaps = 9/96 (9%)

Query: 121 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKK-----AKKPAAATVTKKVAKSPK 175
           K+   T PK+P  A   PKK A   TPK+ A  TPK+      KKPA  T  +    +PK
Sbjct: 558 KEPAPTTPKEP--APTTPKKPAP-TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 614

Query: 176 KAKVAKPKKAAKSAAKAVKPKA-AKPKVVKPKKAAP 210
           +     PKK   +  + + P    KP    P++ AP
Sbjct: 615 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 650



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 9/105 (8%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKK------PKKAAGGATPKKS---AKKTPKKAKKPAAAT 165
           E  P   K+  T PK+P     K      PK+ A   T + +    K  P   K+PA  T
Sbjct: 380 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 439

Query: 166 VTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
             K    +PK+     PK+   +  K   P   +P    PK+ AP
Sbjct: 440 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP 484



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 34/101 (33%), Positives = 46/101 (45%), Gaps = 9/101 (8%)

Query: 116 AKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKA-----KKPAAATVTKKV 170
           A    KK   T PK+P  A   PK+ A   TPKK    TP+K      +KPA  T  +  
Sbjct: 593 APTTTKKPAPTTPKEP--APTTPKETAP-TTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 649

Query: 171 AKSPKKAKVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAP 210
             +P++     P++ A +  KA  P   K P    PK+ AP
Sbjct: 650 PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 690



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 1/91 (1%)

Query: 121 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA 180
           KK   T PK+P     K         P  +  K P      +A T TK+ A +  K+   
Sbjct: 488 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 547

Query: 181 KPKKAAKSAAKAVKPKAAK-PKVVKPKKAAP 210
            PK+ + +  K   P   K P    PKK AP
Sbjct: 548 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 578



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 8/94 (8%)

Query: 121 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKA----KKPAAATVTKKVAKSPKK 176
           K+   T PK+P     K    +   TPK+ A  T K A    K+PA  T  +    +PK+
Sbjct: 356 KEPASTTPKEPTPTTIK----SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 411

Query: 177 AKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
                 K+ A +  K+      +P    PKK AP
Sbjct: 412 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP 445



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 29/99 (29%), Positives = 40/99 (40%), Gaps = 7/99 (7%)

Query: 116 AKPKVKKAGGTKPKKPVGAAKKPKKA----AGGATPKKSAKKTPKKAKKPAAATVTKKVA 171
           A    K+   T PK+P     K        +   TPK+ A  TP   KKPA  T  +   
Sbjct: 397 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP---KKPAPTTPKEPAP 453

Query: 172 KSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
            +PK+     PK+ A +  +       +P    PKK AP
Sbjct: 454 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 492



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 29/98 (29%), Positives = 40/98 (40%), Gaps = 8/98 (8%)

Query: 121 KKAGGTKPKKPVGAAKKP----KKAAGGATPKKSAKKTPKK----AKKPAAATVTKKVAK 172
           K+   T PK+P    K+P     K      PKK A  TPK+      K  A T TK+ + 
Sbjct: 457 KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 516

Query: 173 SPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
           +  K       K+A +  K   P   K     PK+ +P
Sbjct: 517 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 554



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 32/104 (30%), Positives = 41/104 (39%), Gaps = 9/104 (8%)

Query: 116 AKPKVKKAGGTKPKKPVGAAKKPKKAA---GGATPKKSAKKTPKK-----AKKPAAATVT 167
           A    K+   T PK+P     K           T  KSA  TPK+      K+PA  T  
Sbjct: 507 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 566

Query: 168 KKVAKSPKKAKVAKPKKAAKSAAKAVKPKAA-KPKVVKPKKAAP 210
           +    +PKK     PK+ A +  K   P    KP    PK+ AP
Sbjct: 567 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 610



 Score = 40.8 bits (94), Expect = 9e-04
 Identities = 31/101 (30%), Positives = 40/101 (39%), Gaps = 8/101 (7%)

Query: 115 EAKPKVKKAGGTKPKKPVGAAKKPK----KAAGGATPKKSAKKTPKKAKKPAAATVTKKV 170
           E  P   K+  T  K+P     K      K     T K+ A  TP   K+PA  T  K  
Sbjct: 521 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP---KEPAPTTPKKPA 577

Query: 171 AKSPKKAKVAKPKKAAKSAAKAVKPKAAK-PKVVKPKKAAP 210
             +PK+     PK+ A +  K   P   K P    PK+ AP
Sbjct: 578 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP 618



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 52/215 (24%), Positives = 70/215 (32%), Gaps = 24/215 (11%)

Query: 2   SETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAA 61
           +ET    PA   P E  P   K  + A  TP++    P    I  A    KE +  +  +
Sbjct: 335 AETTTKGPALTTPKEPTPTTPK--EPASTTPKE----PTPTTIKSAPTTPKEPAPTTTKS 388

Query: 62  LKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVK 121
                        K  +           K     T    A  + K         A    K
Sbjct: 389 APTTPKEPAPTTTKEPA-------PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 441

Query: 122 KAGGTKPKKPVGAAKK------PKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPK 175
           K   T PK+P     K      PK+ A   T K+ A  TP   K+PA     K    +PK
Sbjct: 442 KPAPTTPKEPAPTTPKEPTPTTPKEPA--PTTKEPAPTTP---KEPAPTAPKKPAPTTPK 496

Query: 176 KAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
           +     PK+ A +  K   P   K       K+AP
Sbjct: 497 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 531



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 56/217 (25%), Positives = 73/217 (33%), Gaps = 15/217 (6%)

Query: 4    TAPAAPAAAPPAEKAPVK-KKAAKKAGGTPRKASGPPVSELITK---AVAASKERSGVSL 59
            T P   A   P E AP   KK A     TP   +    +   TK    +  S + S   L
Sbjct: 821  TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 880

Query: 60   AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK 119
            +A     A      E      K    +     T  + K T       L     +  A PK
Sbjct: 881  SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD----LRTTPETTTAAPK 936

Query: 120  VKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKV 179
            + K   T  +K   +  K        T   +   TP K       T+  KV  + K    
Sbjct: 937  MTKETATTTEKTTES--KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITT 994

Query: 180  A----KPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKK 212
                 KP++ AK   +A   KA  PK  KP K APKK
Sbjct: 995  TEIMNKPEETAKPKDRATNSKATTPKPQKPTK-APKK 1030



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 50/219 (22%), Positives = 71/219 (32%), Gaps = 23/219 (10%)

Query: 14  PAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDV 73
           P  K PV  +A         K + P  S      V+ S + +       + +L     D 
Sbjct: 212 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNS-DT 270

Query: 74  EKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLN--------KKAASGEAKPKVKKAGG 125
            K  S       ++ +K T    K T   G  K          +K ++ +  P  K    
Sbjct: 271 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 330

Query: 126 TKPKKPV---GAAKKPKKAAGGATPKKSAKKTPKK-----------AKKPAAATVTKKVA 171
             PK      G A    K     TPK+ A  TPK+             K  A T TK   
Sbjct: 331 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 390

Query: 172 KSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
            +PK+      K+ A +  K   P   K       K+AP
Sbjct: 391 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 429



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 30/101 (29%), Positives = 40/101 (39%), Gaps = 11/101 (10%)

Query: 121 KKAGGTKPKKPVGAAKKPK-----KAAGGATPKKSAKKTPKKA-----KKPAAATVTKKV 170
           KK   T PK+P     K       K     TPK+ A  TPK+      KK    T  K  
Sbjct: 574 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 633

Query: 171 AKSPKKAKVAKPKKAAKSAAKAVKPKA-AKPKVVKPKKAAP 210
             +P+K     P++ A +  +   P    +P    PK AAP
Sbjct: 634 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 674



 Score = 34.7 bits (78), Expect = 0.062
 Identities = 48/229 (20%), Positives = 86/229 (37%), Gaps = 30/229 (13%)

Query: 9   PAAAPPAEKAPVKKKAAKKAGGTPRKASGPP-------------------VSELITKAVA 49
           P + P ++KAP    A++    T +++  PP                   VSE    + +
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 169

Query: 50  ASKERSGVSLAALKKAL-AAAGYDVEK----NNSRIKLGLKSLVSKGTLVQTKGTGA-SG 103
           +S   S  ++  +K +  +AA  +++K     +++     K    K  +V   G+G  +G
Sbjct: 170 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNG 229

Query: 104 SFKLNKKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAK-KPA 162
            FK+     S     KV  +      KP+    +P       T K+++    K+   +  
Sbjct: 230 DFKVTTPDTSTTQHNKVSTSPKITTAKPIN--PRPSLPPNSDTSKETSLTVNKETTVETK 287

Query: 163 AATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPK 211
             T T K   +  K K    K+       + K  A   KV+   K  PK
Sbjct: 288 ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL--AKPTPK 334



 Score = 33.5 bits (75), Expect = 0.14
 Identities = 52/226 (23%), Positives = 75/226 (33%), Gaps = 25/226 (11%)

Query: 4   TAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALK 63
           T P  PA   P E AP   K    A  T ++ +     +   K +A +  +   S    K
Sbjct: 691 TTPKEPAPTTPKETAPTTPKGT--APTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 748

Query: 64  KALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKKA 123
            A               K    +   +      KGT  +    L + A +   KP  K+ 
Sbjct: 749 PAPTTPKGTAPTTP---KEPAPTTPKEPAPTTPKGTAPT---TLKEPAPTTPKKPAPKEL 802

Query: 124 GGTKPKKPVG------AAKKPKKAA-------GGATPKKSAKKTPKKAKKPAAATVTKKV 170
             T  K P        A   PK+ A          TPKK A  TP+      +   T   
Sbjct: 803 APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTT 862

Query: 171 AKSP----KKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKK 212
            K P    K    + P+ +A+   KA++    +P V   K  A  K
Sbjct: 863 TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 908



 Score = 31.6 bits (70), Expect = 0.52
 Identities = 43/182 (23%), Positives = 61/182 (33%), Gaps = 22/182 (12%)

Query: 2    SETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAA 61
            S   P  P    PA   P     AK    T R     P  E  T A   +KE +  +   
Sbjct: 892  SPKEPGVPTTKTPAATKPEMTTTAKDKT-TERDLRTTP--ETTTAAPKMTKETATTTEKT 948

Query: 62   LKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFK----LNKKAASGEAK 117
             +  + A    V    ++     K    K T +  K T    +      +NK   + + K
Sbjct: 949  TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPK 1008

Query: 118  PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKA 177
             +   +  T PK      +KP KA     PKK     P   KKP      +K   +P   
Sbjct: 1009 DRATNSKATTPKP-----QKPTKA-----PKK-----PTSTKKPKTMPRVRKPKTTPTPR 1053

Query: 178  KV 179
            K+
Sbjct: 1054 KM 1055



 Score = 31.2 bits (69), Expect = 0.68
 Identities = 52/217 (23%), Positives = 72/217 (33%), Gaps = 19/217 (8%)

Query: 5    APAAPAAAPPAEK---APVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSL-- 59
            AP  P   PP       P   K       +P +++    +E   KA+  S +  GV    
Sbjct: 843  APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTK 902

Query: 60   --AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 117
              AA K  +     D  K   R  L      +      TK T  +       K  +   +
Sbjct: 903  TPAATKPEMTTTAKD--KTTER-DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 959

Query: 118  PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKT-----PKKAKKPAAATVTKKVAK 172
                    T P K +   K    A    T KK+   T     P++  KP       K A 
Sbjct: 960  VTSTTTQDTTPFK-ITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSK-AT 1017

Query: 173  SPKKAKVAK-PKKAAKSAAKAVKPKAAKPKVV-KPKK 207
            +PK  K  K PKK   +      P+  KPK    P+K
Sbjct: 1018 TPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 1054



 Score = 28.5 bits (62), Expect = 4.4
 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 18/100 (18%)

Query: 128 PKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKS---PKKAKVAKPKK 184
           P  P  + K P  +    T K + K++PK   K      TKKV +S    ++  V++ ++
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKK----TKKVIESEEITEEHSVSENQE 165

Query: 185 AAKSAA-----------KAVKPKAAKPKVVKPKKAAPKKK 213
           ++ S++           K+ K  AA  ++ K  K    KK
Sbjct: 166 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKK 205


>gi|9257222 forkhead box O1 [Homo sapiens]
          Length = 655

 Score = 48.1 bits (113), Expect = 5e-06
 Identities = 49/173 (28%), Positives = 69/173 (39%), Gaps = 34/173 (19%)

Query: 6   PAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGP--------PVSELITKAVAASKERSGV 57
           P  P   P ++  PV   AA    G PRK+S            ++LITKA+ +S E+   
Sbjct: 123 PQPPPPGPLSQHPPVPPAAAGPLAGQPRKSSSSRRNAWGNLSYADLITKAIESSAEKRLT 182

Query: 58  SLAALKKALAAAGYDVEKNNSRIKLGLK-------SLVSKGTLVQTKGTGASGSFKLNKK 110
                +  + +  Y  +K +S    G K       SL SK   VQ +GTG S  + LN +
Sbjct: 183 LSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLNPE 242

Query: 111 AASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAA 163
                        GG   K P       ++AA      K AK   + AKK A+
Sbjct: 243 -------------GGKSGKSP------RRRAASMDNNSKFAKSRSRAAKKKAS 276


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 48.1 bits (113), Expect = 5e-06
 Identities = 53/220 (24%), Positives = 89/220 (40%), Gaps = 14/220 (6%)

Query: 3   ETAPAAPAAAPPAEK---APVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSL 59
           + AP+ PA          A   K  A K    P++  G     L  KA ++S E    S 
Sbjct: 374 DEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSS 433

Query: 60  AALK-KALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKP 118
              K K + A         + + L  K    +G+   +  + +S S +  +K +    K 
Sbjct: 434 EEEKTKKMVATTKPKATAKAALSLPAKQ-APQGSRDSSSDSDSSSSEEEEEKTSKSAVKK 492

Query: 119 KVKK-AGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAK--------KPAAATVTKK 169
           K +K AGG  P KP  A K   +++  ++   S+++  +K K         P A   +  
Sbjct: 493 KPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSAL 552

Query: 170 VAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAA 209
            A++ K AK ++ ++  K  A  V  K+   K  K  +AA
Sbjct: 553 TAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAA 592



 Score = 47.4 bits (111), Expect = 9e-06
 Identities = 54/220 (24%), Positives = 92/220 (41%), Gaps = 28/220 (12%)

Query: 20  VKKKAAKKAGGTPRKASGPPVSELIT---KAVAASKERSGVSLAALKKALAAAGYDVEKN 76
           V  K AK  G T + A+   + ++ +   K+    + +   +    KKA   A     ++
Sbjct: 30  VANKFAKATGATQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKASSSDSED 89

Query: 77  NSRIKLGLKSLVSKGTLVQTKGTG---ASGSFKLNKKAASGEAKPKVKKAGGTKPKKPVG 133
           +S  +  ++   +K   V  K  G      + K ++ ++S E+     +    + K+PV 
Sbjct: 90  SSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEED--QKKQPVQ 147

Query: 134 AAKKPKKAAGGATPKK----------SAKKTPKKAKKPAAATVTKKV-AKSPKKAKVAKP 182
              KP+  A  A PKK          S++  P K +KP    VT K   K+P K   A P
Sbjct: 148 KGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAP 207

Query: 183 K----KAAKSAAKAVKPKAA-----KPKVVKPKKAAPKKK 213
           K    KAA S++ +    ++     +     PKK  PKK+
Sbjct: 208 KIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQ 247



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 57/229 (24%), Positives = 82/229 (35%), Gaps = 44/229 (19%)

Query: 19  PVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNS 78
           PV  KA  KA   P +A+    +     + ++S   S    +  +KA A     V K   
Sbjct: 189 PVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQV 248

Query: 79  RIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKKAGGTKPKKPVGAAKKP 138
             K  +K+         T  T  S S + +      E K  +K   G     P  +A  P
Sbjct: 249 VAKAPVKAA--------TTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPP 300

Query: 139 KKAAGGATPKKSAKK-----------------TPKKAKKPAAATVTKKVAKSPKKAKVAK 181
           KK+ G   PKK+ +K                 + ++ K P  A V+K   K P   K A+
Sbjct: 301 KKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAE 360

Query: 182 PK------------KAAKSAAKAVKPKAAKPKV------VKPKKAAPKK 212
                         +A    A   K  + KP V      VKP  AAPK+
Sbjct: 361 SSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKP-AAAPKQ 408


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score = 47.8 bits (112), Expect = 7e-06
 Identities = 56/195 (28%), Positives = 79/195 (40%), Gaps = 34/195 (17%)

Query: 22  KKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDV---EKNNS 78
           ++  +KA  T  K    P       A A SK R     A  +KA AAAG      EK   
Sbjct: 124 RRRGQKAAATGSKK---PRWRAQKSAAAGSKNRG----AGAQKAAAAAGVKSQGGEKPQK 176

Query: 79  RIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKKAGGTKPKKPVGAAKKP 138
               G KS   K    + +  GA      +KK    EAK +  K  G + KK     ++P
Sbjct: 177 AAAAGAKSRSGK----KPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKH----RRP 228

Query: 139 KKAAGGATPKKSAKKTPKKAKKPAAATVT--------------KKVAKSPKKAKVAKPKK 184
           K AAGGA  ++   K P+K ++      T              KK+ +  + A +A  K+
Sbjct: 229 KPAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKR 288

Query: 185 AAKSAAKAVKPKAAK 199
             + AA A +  AAK
Sbjct: 289 --RGAATAGEKPAAK 301



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 52/200 (26%), Positives = 74/200 (37%), Gaps = 18/200 (9%)

Query: 21  KKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKN---- 76
           K +  K  GG  +K     +      A  A  +R G + A  K A    G    K+    
Sbjct: 260 KSRVGKSRGGGDKK-----LRRQGQNAALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQ 314

Query: 77  NSRIKLGLKSLVSKG---TLVQTKGTGASGSFKLNKKAASGEAKPKVKKAGGTKPKKPVG 133
           N R   G K    +G   T     GT   G  +  K A  G    K ++  G KP++   
Sbjct: 315 NPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQ-QKAAVVGVKSRKKQRRRGKKPRRQKA 373

Query: 134 AAKKPKKAAGGATPK-KSAKKTPKKAKKPAAATVTKKVAKSPKKAKVAKPKKAAKSAAKA 192
           +A   K   GG     + AK+     KKP      ++  K+P     AKP+       + 
Sbjct: 374 SAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAP----AAKPRGGGSKKPRR 429

Query: 193 VKPKAAKPKVVKPKKAAPKK 212
             PKAAK +  K +    KK
Sbjct: 430 RGPKAAKSRGGKSRSGGGKK 449



 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 46/203 (22%), Positives = 75/203 (36%), Gaps = 19/203 (9%)

Query: 7   AAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPV----SELITKAVAASKERSGVSLAAL 62
           AA A   PA K    +      G  PR   G        +  TKA AA  +R G      
Sbjct: 291 AATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGG---- 346

Query: 63  KKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK--- 119
           ++  A  G    K   R     +   +     +++G G     +  K+   G  KP+   
Sbjct: 347 QQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQN 406

Query: 120 ----VKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKP--AAATVTKKVAKS 173
                +KA   KP+   G +KKP++    A   +  K      KKP        +K A++
Sbjct: 407 PRRRAQKAPAAKPRG--GGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEA 464

Query: 174 PKKAKVAKPKKAAKSAAKAVKPK 196
             +++  K +   K++A   K +
Sbjct: 465 GAESRGDKKQGRQKASAAGTKSR 487



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 53/225 (23%), Positives = 79/225 (35%), Gaps = 32/225 (14%)

Query: 7   AAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALKKAL 66
           AAPA +  A    +     KK       A G        K   A KE    +    +KA 
Sbjct: 38  AAPALSAAAAGVKILGSGDKKLRRQKAAAGGKKARLRGQKGAVAGKE----ARQHWQKAA 93

Query: 67  AAAGYDVEKNNSR--IKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK---VK 121
            A G +      +     G KSL  +G   + +G          K AA+G  KP+    K
Sbjct: 94  GAGGAENRGGGEQKAAAAGTKSLGGRGRKPRRRG---------QKAAATGSKKPRWRAQK 144

Query: 122 KAGGTKPKKPVGAAK-------------KPKKAAGGATPKKSAKKTPKKAKKPAAATVTK 168
            A      +  GA K             KP+KAA      +S KK P++    +     K
Sbjct: 145 SAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAAAAGAKSRSGKK-PRRRGAKSRGDEDK 203

Query: 169 KVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK 213
           K  +   K++  K +   +   +  KP A   K  +     P+K+
Sbjct: 204 KGRQREAKSRFGKTRGGRRKKHRRPKPAAGGAKSRRGGGKKPQKQ 248



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 62/260 (23%), Positives = 88/260 (33%), Gaps = 58/260 (22%)

Query: 7   AAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELI--TKAVAASKERSGVSLAALKK 64
           AA A A        +++ AK  G   +K            T+     K R     A   K
Sbjct: 177 AAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPKPAAGGAK 236

Query: 65  ALAAAGYDVEKNNSR---IKLGLKSLVSKGT-----LVQTKGTGASGSFKLNKKAASGEA 116
           +    G   +K   R      G KS V K        ++ +G  A+ +    + AA+   
Sbjct: 237 SRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGE 296

Query: 117 KPKVKKAGGTKPK--------------KPVGAAKKPKKAAGGATPK-------------K 149
           KP  K  GG  PK              KP    +K  KAA   T +             K
Sbjct: 297 KPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVK 356

Query: 150 SAKKTPKKAKKPAAATVTKKVAKS------------------PKKAKVAKPKKAAKSAAK 191
           S KK  ++ KKP     +   AKS                   KK +   P++ A+  A 
Sbjct: 357 SRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQK-AP 415

Query: 192 AVKPKAAKPKVVKPKKAAPK 211
           A KP+    K  KP++  PK
Sbjct: 416 AAKPRGGGSK--KPRRRGPK 433



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 47/168 (27%), Positives = 72/168 (42%), Gaps = 17/168 (10%)

Query: 48  VAASKERSGVSLAALKKA----LAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASG 103
           + A+  R+ V LAA   A     AAAG  +  +  + KL  +   + G   + +G     
Sbjct: 22  LGAALARTPVELAAESAAPALSAAAAGVKILGSGDK-KLRRQKAAAGGKKARLRG----- 75

Query: 104 SFKLNKKAASG-EAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPA 162
                K A +G EA+   +KA G    +  G  ++ K AA G        + P++  + A
Sbjct: 76  ----QKGAVAGKEARQHWQKAAGAGGAENRGGGEQ-KAAAAGTKSLGGRGRKPRRRGQKA 130

Query: 163 AATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPK-VVKPKKAA 209
           AAT +KK     +K+  A  K     A KA      K +   KP+KAA
Sbjct: 131 AATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAA 178



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 56/216 (25%), Positives = 80/216 (37%), Gaps = 33/216 (15%)

Query: 24  AAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVE----KNNSR 79
           A +KA     K+ G         AVA +K R G S +  ++   AAG           SR
Sbjct: 509 AGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSR 568

Query: 80  IKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV---------KKAGGT---K 127
              G K      T    K  G        +KAA+G  K +          +KA GT    
Sbjct: 569 GGGGNKPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGAKS 628

Query: 128 PKKP-----VGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVA---------KS 173
            KKP       AA   K  A GAT + S  K P+  K  AA + +   A         K 
Sbjct: 629 RKKPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEARKK 688

Query: 174 PKKAKVAKPKKAAKSAAKAVKP---KAAKPKVVKPK 206
           P++ +        ++AA  + P   +  KP++ K +
Sbjct: 689 PRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLGKSR 724



 Score = 34.3 bits (77), Expect = 0.081
 Identities = 45/187 (24%), Positives = 66/187 (35%), Gaps = 13/187 (6%)

Query: 12  APPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGY 71
           A  AEKA      ++ +GG   +   P  +   + A AA     G    A KK       
Sbjct: 640 AAAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAV----GQEAEARKKPRRRRAK 695

Query: 72  DVEKNNSRIKLGLKSLVSKGTLVQT-KGTGASGSFKLNKKAASGEAKPKVKKAGGTKPKK 130
                     +G+     +G   +  K  G  G+    K   SG AK +   +GG K + 
Sbjct: 696 SRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGA----KSRGSGGAKSR--GSGGAKSRS 749

Query: 131 PVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVAKPK--KAAKS 188
              AA       GGA  ++      +  +K   A   K  A   KK    K +  +  K+
Sbjct: 750 GKKAAASKSHGGGGAKRRRGGGAKSRSGEKAVTAGGQKAAAAGGKKPPRVKSRGGRGQKA 809

Query: 189 AAKAVKP 195
           AA   KP
Sbjct: 810 AAGGKKP 816


>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
           sapiens]
          Length = 1158

 Score = 47.4 bits (111), Expect = 9e-06
 Identities = 36/107 (33%), Positives = 47/107 (43%), Gaps = 12/107 (11%)

Query: 106 KLNKKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAAT 165
           ++ K  A G+   +   A    P+K     KK KK  G   PK+S + +P+  KK     
Sbjct: 65  RVRKAQAGGKPGKRPGTAAEVPPEKTKDKGKKGKKDKGPKVPKESLEGSPRPPKKGK--- 121

Query: 166 VTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKK 212
             +K  K+ KK K  KP KA K      KPK   PK  K  K  P K
Sbjct: 122 --EKPPKATKKPK-EKPPKATK------KPKEKPPKATKKPKEKPPK 159



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 35/103 (33%), Positives = 48/103 (46%), Gaps = 7/103 (6%)

Query: 109 KKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGAT--PKKSAKKTPKKAKKP--AAA 164
           +   + E  P+  K  G K KK  G  K PK++  G+   PKK  +K PK  KKP     
Sbjct: 78  RPGTAAEVPPEKTKDKGKKGKKDKGP-KVPKESLEGSPRPPKKGKEKPPKATKKPKEKPP 136

Query: 165 TVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKK 207
             TKK  + P KA   KPK+    A K   P   +P ++ P +
Sbjct: 137 KATKKPKEKPPKA-TKKPKEKPPKATKK-PPSGKRPPILAPSE 177


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 41/92 (44%), Positives = 43/92 (46%), Gaps = 10/92 (10%)

Query: 106 KLNKKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTP-KKAKKPAAA 164
           K  KKAA+  AK  V       P K V  A   KKAA   TP K A  TP KK   PA A
Sbjct: 51  KKGKKAAATSAKKVV-----VSPTKKVAVATPAKKAA--VTPGKKAAATPAKKTVTPAKA 103

Query: 165 TVTK-KVAKSPKKAKVAKP-KKAAKSAAKAVK 194
             T  K   +P KA VA P KK A   AK  K
Sbjct: 104 VTTPGKKGATPGKALVATPGKKGAAIPAKGAK 135



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 35/81 (43%), Positives = 38/81 (46%), Gaps = 9/81 (11%)

Query: 136 KKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVAKPKKAAKSAAKAVK- 194
           KK KKAA  AT  K    +P   KK A AT  KK A +P K   A P K   + AKAV  
Sbjct: 51  KKGKKAA--ATSAKKVVVSP--TKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTT 106

Query: 195 --PKAAKPKVVKPKKAAPKKK 213
              K A P   K   A P KK
Sbjct: 107 PGKKGATPG--KALVATPGKK 125



 Score = 34.3 bits (77), Expect = 0.081
 Identities = 25/68 (36%), Positives = 30/68 (44%), Gaps = 2/68 (2%)

Query: 147 PKKSAKKTPKKAKKPAAATVTKKVAKS--PKKAKVAKPKKAAKSAAKAVKPKAAKPKVVK 204
           P+K  KK    + K    + TKKVA +   KKA V   KKAA + AK     A       
Sbjct: 49  PQKKGKKAAATSAKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPG 108

Query: 205 PKKAAPKK 212
            K A P K
Sbjct: 109 KKGATPGK 116


>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
            sapiens]
          Length = 2971

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 39/103 (37%), Positives = 44/103 (42%), Gaps = 9/103 (8%)

Query: 117  KPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKK-TPKK--AKKPAA---ATVTKKV 170
            KP       T   KPV    KP       + K +A K  P K  A KP A   ATV   V
Sbjct: 2669 KPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPV 2728

Query: 171  AKSPKKAK---VAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
            A  P  A     AKP      AA A KP A KP+V +P+ A P
Sbjct: 2729 AVKPATAAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKP 2771



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 34/98 (34%), Positives = 40/98 (40%), Gaps = 10/98 (10%)

Query: 117  KPKVKKAGGTK-PKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPK 175
            +P VK A     P KPV A     K A   T +      P  A KP AA   K  A  P 
Sbjct: 2696 QPSVKPAAAKPAPAKPVAAKPVATKMA---TVRPPVAVKPATAAKPVAA---KPAAVRPP 2749

Query: 176  KAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK 213
             A  AKP     +  +  +P+AAKP   KP    P  K
Sbjct: 2750 AAAAAKP---VATKPEVPRPQAAKPAATKPATTKPMVK 2784



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 31/90 (34%), Positives = 36/90 (40%), Gaps = 12/90 (13%)

Query: 116  AKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPK 175
            AKP   K    KP     A  +P  A   AT  K     P   + PAAA   K VA  P 
Sbjct: 2704 AKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAA-AAKPVATKP- 2761

Query: 176  KAKVAKPKKAAKSAAKAVKPKAAKPKVVKP 205
              +V +P        +A KP A KP   KP
Sbjct: 2762 --EVPRP--------QAAKPAATKPATTKP 2781



 Score = 28.1 bits (61), Expect = 5.8
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)

Query: 110  KAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPK-KAKKPAAA--TV 166
            K A+      VK A   KP     AA +P  AA  A P  +  + P+ +A KPAA     
Sbjct: 2720 KMATVRPPVAVKPATAAKPVAAKPAAVRPP-AAAAAKPVATKPEVPRPQAAKPAATKPAT 2778

Query: 167  TKKVAKSPKKAKV 179
            TK + K  ++ +V
Sbjct: 2779 TKPMVKMSREVQV 2791


>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
            sapiens]
          Length = 3177

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 39/103 (37%), Positives = 44/103 (42%), Gaps = 9/103 (8%)

Query: 117  KPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKK-TPKK--AKKPAA---ATVTKKV 170
            KP       T   KPV    KP       + K +A K  P K  A KP A   ATV   V
Sbjct: 2875 KPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPV 2934

Query: 171  AKSPKKAK---VAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
            A  P  A     AKP      AA A KP A KP+V +P+ A P
Sbjct: 2935 AVKPATAAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKP 2977



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 34/98 (34%), Positives = 40/98 (40%), Gaps = 10/98 (10%)

Query: 117  KPKVKKAGGTK-PKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPK 175
            +P VK A     P KPV A     K A   T +      P  A KP AA   K  A  P 
Sbjct: 2902 QPSVKPAAAKPAPAKPVAAKPVATKMA---TVRPPVAVKPATAAKPVAA---KPAAVRPP 2955

Query: 176  KAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK 213
             A  AKP     +  +  +P+AAKP   KP    P  K
Sbjct: 2956 AAAAAKP---VATKPEVPRPQAAKPAATKPATTKPMVK 2990



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 31/90 (34%), Positives = 36/90 (40%), Gaps = 12/90 (13%)

Query: 116  AKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPK 175
            AKP   K    KP     A  +P  A   AT  K     P   + PAAA   K VA  P 
Sbjct: 2910 AKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAA-AAKPVATKP- 2967

Query: 176  KAKVAKPKKAAKSAAKAVKPKAAKPKVVKP 205
              +V +P        +A KP A KP   KP
Sbjct: 2968 --EVPRP--------QAAKPAATKPATTKP 2987



 Score = 28.1 bits (61), Expect = 5.8
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)

Query: 110  KAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPK-KAKKPAAA--TV 166
            K A+      VK A   KP     AA +P  AA  A P  +  + P+ +A KPAA     
Sbjct: 2926 KMATVRPPVAVKPATAAKPVAAKPAAVRPP-AAAAAKPVATKPEVPRPQAAKPAATKPAT 2984

Query: 167  TKKVAKSPKKAKV 179
            TK + K  ++ +V
Sbjct: 2985 TKPMVKMSREVQV 2997


>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
            sapiens]
          Length = 2570

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 39/103 (37%), Positives = 44/103 (42%), Gaps = 9/103 (8%)

Query: 117  KPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKK-TPKK--AKKPAA---ATVTKKV 170
            KP       T   KPV    KP       + K +A K  P K  A KP A   ATV   V
Sbjct: 2268 KPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPV 2327

Query: 171  AKSPKKAK---VAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAP 210
            A  P  A     AKP      AA A KP A KP+V +P+ A P
Sbjct: 2328 AVKPATAAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKP 2370



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 34/98 (34%), Positives = 40/98 (40%), Gaps = 10/98 (10%)

Query: 117  KPKVKKAGGTK-PKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPK 175
            +P VK A     P KPV A     K A   T +      P  A KP AA   K  A  P 
Sbjct: 2295 QPSVKPAAAKPAPAKPVAAKPVATKMA---TVRPPVAVKPATAAKPVAA---KPAAVRPP 2348

Query: 176  KAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK 213
             A  AKP     +  +  +P+AAKP   KP    P  K
Sbjct: 2349 AAAAAKP---VATKPEVPRPQAAKPAATKPATTKPMVK 2383



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 31/90 (34%), Positives = 36/90 (40%), Gaps = 12/90 (13%)

Query: 116  AKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPK 175
            AKP   K    KP     A  +P  A   AT  K     P   + PAAA   K VA  P 
Sbjct: 2303 AKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAA-AAKPVATKP- 2360

Query: 176  KAKVAKPKKAAKSAAKAVKPKAAKPKVVKP 205
              +V +P        +A KP A KP   KP
Sbjct: 2361 --EVPRP--------QAAKPAATKPATTKP 2380



 Score = 28.1 bits (61), Expect = 5.8
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)

Query: 110  KAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPK-KAKKPAAA--TV 166
            K A+      VK A   KP     AA +P  AA  A P  +  + P+ +A KPAA     
Sbjct: 2319 KMATVRPPVAVKPATAAKPVAAKPAAVRPP-AAAAAKPVATKPEVPRPQAAKPAATKPAT 2377

Query: 167  TKKVAKSPKKAKV 179
            TK + K  ++ +V
Sbjct: 2378 TKPMVKMSREVQV 2390


>gi|29244924 chromodomain helicase DNA binding protein 6 [Homo
           sapiens]
          Length = 2715

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 43/133 (32%), Positives = 60/133 (45%), Gaps = 26/133 (19%)

Query: 94  VQTKGTGASGSFKLNKKAASGEAK----------PKVKKAGGTKPKKPVGAAKKPKKAAG 143
           ++  G G +G  K  KK   G+ +          PK K+    K  K    AK+PKKA  
Sbjct: 82  MEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKAKEPKKAKE 141

Query: 144 GATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVAKPKKA-AKSAAKAVKPKAAK--- 199
              PK+  K   KKA+KP  A+ TK+          AK K++   SAA+    KA+K   
Sbjct: 142 HKEPKQ--KDGAKKARKPREASGTKE----------AKEKRSCTDSAARTKSRKASKEQG 189

Query: 200 PKVVKPKKAAPKK 212
           P  V+ KK   +K
Sbjct: 190 PTPVEKKKKGKRK 202



 Score = 34.3 bits (77), Expect = 0.081
 Identities = 32/143 (22%), Positives = 58/143 (40%), Gaps = 5/143 (3%)

Query: 70  GYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKKAGGTKPK 129
           G  V+K   + + G +   +KG+  +          K  K+    +   K K+    K K
Sbjct: 89  GTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKAKEPKKAKEHKEPKQK 148

Query: 130 KPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVAKPKKAAKSA 189
                A+KP++A+G     K AK+  +     AA T ++K +K      V K KK  + +
Sbjct: 149 DGAKKARKPREASG----TKEAKE-KRSCTDSAARTKSRKASKEQGPTPVEKKKKGKRKS 203

Query: 190 AKAVKPKAAKPKVVKPKKAAPKK 212
              V+       +  P   +P++
Sbjct: 204 ETTVESLELDQGLTNPSLRSPEE 226


>gi|118498359 ribosomal L1 domain containing 1 [Homo sapiens]
          Length = 490

 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 51/198 (25%), Positives = 84/198 (42%), Gaps = 23/198 (11%)

Query: 16  EKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERS---GVSLAALKKALAAAGYD 72
           E+   +++A K A    +    P   +   K   + KE++   G       KA   A  +
Sbjct: 301 ERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNE 360

Query: 73  VEKNNSR-IKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKKAGGTKPKKP 131
            E    + + +G K+  ++   +Q   TG        KK+ +    P   +    K +K 
Sbjct: 361 SEDEIPQLVPIGKKTPANEKVEIQKHATG--------KKSPAKSPNPSTPRG---KKRKA 409

Query: 132 VGAAKKPKKAAGGATPKKSAKKTPK---KAKKPAAATVTKKVAKSPKKAKVAK----PKK 184
           + A++ PK AA   TP KS +K PK   +A K  + ++ KK A+   K   AK    P K
Sbjct: 410 LPASETPK-AAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSK 468

Query: 185 AAKSAAKAVKPKAAKPKV 202
           + + A+   K    KPKV
Sbjct: 469 SVRKASHTPKKWPKKPKV 486



 Score = 35.4 bits (80), Expect = 0.036
 Identities = 48/207 (23%), Positives = 78/207 (37%), Gaps = 10/207 (4%)

Query: 15  AEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVE 74
           +EK P K ++ K       K++  P+          + +RS ++    +        + E
Sbjct: 238 SEKLPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFE 297

Query: 75  KNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKKAGGTKPKKPVGA 134
           K   R K   ++  +   L +      SG   + K  +  E  P+  K    + K  V A
Sbjct: 298 KQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKA 357

Query: 135 AKKPKKAAGGATPKKSAKKTP--KKAKKPAAATVTKKVAKSPK------KAKVAKPKKAA 186
             + +       P    KKTP  +K +    AT  K  AKSP       K + A P    
Sbjct: 358 TNESEDEIPQLVP--IGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASET 415

Query: 187 KSAAKAVKPKAAKPKVVKPKKAAPKKK 213
             AA++  P  +  K  K K+ A K+K
Sbjct: 416 PKAAESETPGKSPEKKPKIKEEAVKEK 442



 Score = 31.6 bits (70), Expect = 0.52
 Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 16/114 (14%)

Query: 109 KKAASGEAKPKVKKAGGTKPKKPVGAAKKP---------KKAAGGATPKKSAKKTPKKAK 159
           KK   G+A+ K       +  + V   KK          K A G  +P KS   +  + K
Sbjct: 346 KKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGK 405

Query: 160 K----PAAATVTKKVAKSPKKAKVAKPK---KAAKSAAKAVKPKAAKPKVVKPK 206
           K    PA+ T     +++P K+   KPK   +A K  + ++  K A+    KP+
Sbjct: 406 KRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPE 459


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.300    0.116    0.302 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,191,673
Number of Sequences: 37866
Number of extensions: 377973
Number of successful extensions: 6009
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 238
Number of HSP's successfully gapped in prelim test: 466
Number of HSP's that attempted gapping in prelim test: 2972
Number of HSP's gapped (non-prelim): 2154
length of query: 213
length of database: 18,247,518
effective HSP length: 98
effective length of query: 115
effective length of database: 14,536,650
effective search space: 1671714750
effective search space used: 1671714750
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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