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Search of human proteins with 4758022
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758022 cochlin precursor [Homo sapiens]
(550 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|205277471 cochlin precursor [Homo sapiens] 1104 0.0
gi|4758022 cochlin precursor [Homo sapiens] 1104 0.0
gi|21359974 vitrin [Homo sapiens] 375 e-104
gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens] 160 4e-39
gi|156616290 collagen type VI alpha 6 [Homo sapiens] 155 7e-38
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s... 154 3e-37
gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens] 147 2e-35
gi|13699836 matrilin 4 isoform 3 precursor [Homo sapiens] 145 7e-35
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s... 140 4e-33
gi|240255540 alpha 3 type VI collagen isoform 3 precursor [Homo ... 140 4e-33
gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo ... 138 1e-32
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 132 8e-31
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ... 129 5e-30
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 120 3e-27
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 119 9e-27
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 117 3e-26
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 108 1e-23
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 108 1e-23
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 105 8e-23
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] 104 2e-22
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] 104 2e-22
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 103 4e-22
gi|13699834 matrilin 4 isoform 2 precursor [Homo sapiens] 103 5e-22
gi|13699830 matrilin 4 isoform 1 precursor [Homo sapiens] 103 5e-22
gi|38348304 von Willebrand factor A domain containing 2 [Homo sa... 95 2e-19
gi|11321565 matrilin 3 precursor [Homo sapiens] 89 8e-18
gi|40068485 von Willebrand factor A domain containing 1 isoform ... 79 8e-15
gi|34452173 integrin alpha X precursor [Homo sapiens] 79 1e-14
gi|148886654 polydom [Homo sapiens] 76 7e-14
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 76 9e-14
>gi|205277471 cochlin precursor [Homo sapiens]
Length = 550
Score = 1104 bits (2855), Expect = 0.0
Identities = 550/550 (100%), Positives = 550/550 (100%)
Query: 1 MSAAWIPALGLGVCLLLLPGPAGSEGAAPIAITCFTRGLDIRKEKADVLCPGGCPLEEFS 60
MSAAWIPALGLGVCLLLLPGPAGSEGAAPIAITCFTRGLDIRKEKADVLCPGGCPLEEFS
Sbjct: 1 MSAAWIPALGLGVCLLLLPGPAGSEGAAPIAITCFTRGLDIRKEKADVLCPGGCPLEEFS 60
Query: 61 VYGNIVYASVSSICGAAVHRGVISNSGGPVRVYSLPGRENYSSVDANGIQSQMLSRWSAS 120
VYGNIVYASVSSICGAAVHRGVISNSGGPVRVYSLPGRENYSSVDANGIQSQMLSRWSAS
Sbjct: 61 VYGNIVYASVSSICGAAVHRGVISNSGGPVRVYSLPGRENYSSVDANGIQSQMLSRWSAS 120
Query: 121 FTVTKGKSSTQEATGQAVSTAHPPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRR 180
FTVTKGKSSTQEATGQAVSTAHPPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRR
Sbjct: 121 FTVTKGKSSTQEATGQAVSTAHPPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRR 180
Query: 181 FNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGG 240
FNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGG
Sbjct: 181 FNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGG 240
Query: 241 NSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVS 300
NSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVS
Sbjct: 241 NSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVS 300
Query: 301 VAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSK 360
VAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSK
Sbjct: 301 VAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSK 360
Query: 361 TCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFS 420
TCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFS
Sbjct: 361 TCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFS 420
Query: 421 FTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIVTDGQSYD 480
FTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIVTDGQSYD
Sbjct: 421 FTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIVTDGQSYD 480
Query: 481 DVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRG 540
DVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRG
Sbjct: 481 DVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRG 540
Query: 541 ICRDFLESQQ 550
ICRDFLESQQ
Sbjct: 541 ICRDFLESQQ 550
>gi|4758022 cochlin precursor [Homo sapiens]
Length = 550
Score = 1104 bits (2855), Expect = 0.0
Identities = 550/550 (100%), Positives = 550/550 (100%)
Query: 1 MSAAWIPALGLGVCLLLLPGPAGSEGAAPIAITCFTRGLDIRKEKADVLCPGGCPLEEFS 60
MSAAWIPALGLGVCLLLLPGPAGSEGAAPIAITCFTRGLDIRKEKADVLCPGGCPLEEFS
Sbjct: 1 MSAAWIPALGLGVCLLLLPGPAGSEGAAPIAITCFTRGLDIRKEKADVLCPGGCPLEEFS 60
Query: 61 VYGNIVYASVSSICGAAVHRGVISNSGGPVRVYSLPGRENYSSVDANGIQSQMLSRWSAS 120
VYGNIVYASVSSICGAAVHRGVISNSGGPVRVYSLPGRENYSSVDANGIQSQMLSRWSAS
Sbjct: 61 VYGNIVYASVSSICGAAVHRGVISNSGGPVRVYSLPGRENYSSVDANGIQSQMLSRWSAS 120
Query: 121 FTVTKGKSSTQEATGQAVSTAHPPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRR 180
FTVTKGKSSTQEATGQAVSTAHPPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRR
Sbjct: 121 FTVTKGKSSTQEATGQAVSTAHPPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRR 180
Query: 181 FNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGG 240
FNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGG
Sbjct: 181 FNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGG 240
Query: 241 NSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVS 300
NSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVS
Sbjct: 241 NSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVS 300
Query: 301 VAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSK 360
VAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSK
Sbjct: 301 VAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSK 360
Query: 361 TCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFS 420
TCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFS
Sbjct: 361 TCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFS 420
Query: 421 FTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIVTDGQSYD 480
FTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIVTDGQSYD
Sbjct: 421 FTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIVTDGQSYD 480
Query: 481 DVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRG 540
DVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRG
Sbjct: 481 DVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRG 540
Query: 541 ICRDFLESQQ 550
ICRDFLESQQ
Sbjct: 541 ICRDFLESQQ 550
>gi|21359974 vitrin [Homo sapiens]
Length = 693
Score = 375 bits (964), Expect = e-104
Identities = 180/389 (46%), Positives = 263/389 (67%), Gaps = 3/389 (0%)
Query: 158 GNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEF 217
G+ +CK D++FLIDGS +IG+RRF +QK + VA L IG GP +G+VQ ++P F
Sbjct: 301 GDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHF 360
Query: 218 YLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGW 277
LK T+++D+ AI+++ RGG SN G+A+ + FF+ G R G P VVVV +DGW
Sbjct: 361 NLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGW 420
Query: 278 PSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWF 337
P+D +EEA +ARE G+N+F +++ E V + F +KAVCR NGF+S H+ +WF
Sbjct: 421 PTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWF 480
Query: 338 GTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTF 397
G K ++PLV+++C +++ CSKTC NS +I F+IDGSSSVG NFR +L+FV+N+ K F
Sbjct: 481 GLHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEF 540
Query: 398 EISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNV 457
EISD +I AVQ+TY+QR EF F YS+K ++L I+ + Y SGGT+TG AI+F + +
Sbjct: 541 EISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQL 600
Query: 458 FGPIRESPNK-NFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKP 516
F + PNK ++++TDG+SYDDV+ PA AAH G+ +++GVAWA ++L+ +A+ P
Sbjct: 601 FK--KSKPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHP 658
Query: 517 KESHAFFTREFTGLEPIVSDVIRGICRDF 545
H+FF EF L V +I+ IC +F
Sbjct: 659 ARDHSFFVDEFDNLHQYVPRIIQNICTEF 687
Score = 85.9 bits (211), Expect = 9e-17
Identities = 43/96 (44%), Positives = 55/96 (57%)
Query: 32 ITCFTRGLDIRKEKADVLCPGGCPLEEFSVYGNIVYASVSSICGAAVHRGVISNSGGPVR 91
I C + I + V CP GC ++ VYG VYAS SS+CGAAVH GV+ NSGG +
Sbjct: 44 INCDVKAGKIIDPEFIVKCPAGCQDPKYHVYGTDVYASYSSVCGAAVHSGVLDNSGGKIL 103
Query: 92 VYSLPGRENYSSVDANGIQSQMLSRWSASFTVTKGK 127
V + G+ Y +NG+QS L RW SF V + K
Sbjct: 104 VRKVAGQSGYKGSYSNGVQSLSLPRWRESFIVLESK 139
>gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens]
Length = 496
Score = 160 bits (404), Expect = 4e-39
Identities = 118/428 (27%), Positives = 189/428 (44%), Gaps = 66/428 (15%)
Query: 165 DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTS 224
D+ F++D S ++ F K F+ +V L +G VG+V + K EF L+ S
Sbjct: 41 DLVFVVDSSRSVRPVEFEKVKVFLSQVIESLDVGPNATRVGMVNYASTVKQEFSLRAHVS 100
Query: 225 AKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIP---KVVVVFIDGWPSDD 281
+L A++ + + TG A++ K F G R P KVV+V DG P D
Sbjct: 101 KAALLQAVRRIQPLSTGTMTGLAIQFAITKAFGDAEGGRSRSPDISKVVIVVTDGRPQDS 160
Query: 282 IEEAGIVAREFGVNVFIVSV------------AKPIPEELGMVQDVTFVDKAVCRNNGFF 329
+++ AR GV +F + V ++P E + V+ + ++K + F
Sbjct: 161 VQDVSARARASGVELFAIGVGSVDKATLRQIASEPQDEHVDYVESYSVIEKLSRKFQEAF 220
Query: 330 SYHMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCYNS------------------------ 365
+V LC C + C +S
Sbjct: 221 C---------------VVSDLCATGDHDCEQVCISSPGSYTCACHEGFTLNSDGKTCNVC 265
Query: 366 --------VNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRT 417
++ FLIDGS SV NF L+ +F+S I T ++SD A++ VQ++ R
Sbjct: 266 SGGGGSSATDLVFLIDGSKSVRPENFELVKKFISQIVDTLDVSDKLAQVGLVQYSSSVRQ 325
Query: 418 EFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVF---GPIRESPNKNFLVIVT 474
EF + TK+++ A +RN+ YM GT TG A+ + + N F R K ++ T
Sbjct: 326 EFPLGRFHTKKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFTVSSGARPGAQK-VGIVFT 384
Query: 475 DGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIV 534
DG+S D + A A D G +F+VGV A D+L+++AS+P H F+T +F + I
Sbjct: 385 DGRSQDYINDAAKKAKDLGFKMFAVGVGNAVEDELREIASEPVAEHYFYTADFKTINQIG 444
Query: 535 SDVIRGIC 542
+ + IC
Sbjct: 445 KKLQKKIC 452
Score = 97.1 bits (240), Expect = 4e-20
Identities = 67/232 (28%), Positives = 107/232 (46%), Gaps = 15/232 (6%)
Query: 91 RVYSLPGRENYSSVDANGIQSQMLSRWSASFTVTKGKSSTQEATGQAVSTAHPPTGKRLK 150
++ S P E+ V++ + ++ ++ +F V +T + + V + P G
Sbjct: 190 QIASEPQDEHVDYVESYSVIEKLSRKFQEAFCVVSDLCATGDHDCEQVCISSP--GSYTC 247
Query: 151 KTPEKKTGNKDCKA-------------DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGI 197
E T N D K D+ FLIDGS ++ F L K F+ ++ L +
Sbjct: 248 ACHEGFTLNSDGKTCNVCSGGGGSSATDLVFLIDGSKSVRPENFELVKKFISQIVDTLDV 307
Query: 198 GTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFT 257
+ VGLVQ S + EF L F + KD+ A++ + + + TG ALK+ FT
Sbjct: 308 SDKLAQVGLVQYSSSVRQEFPLGRFHTKKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFT 367
Query: 258 VDAGVRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEEL 309
V +G R G KV +VF DG D I +A A++ G +F V V + +EL
Sbjct: 368 VSSGARPGAQKVGIVFTDGRSQDYINDAAKKAKDLGFKMFAVGVGNAVEDEL 419
>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
Length = 2263
Score = 155 bits (393), Expect = 7e-38
Identities = 112/396 (28%), Positives = 194/396 (48%), Gaps = 22/396 (5%)
Query: 150 KKTPEKKTGNKDCK-ADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQ 208
++T K+G D + ADI LIDGS + F+ K F+ +V M I VG VQ
Sbjct: 420 ERTETLKSGCVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQ 479
Query: 209 ASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPK 268
++ +EF + +++ +D+ AI+ + GGN+NTG AL T +P
Sbjct: 480 YADSWDLEFEINKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGNKVPC 539
Query: 269 VVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGF 328
+VV +G D I E RE + V+ + + + +L +++ +K V
Sbjct: 540 HLVVLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQL---REIAGEEKRV------ 590
Query: 329 FSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLE 388
Y++ ++ +VQ++CT E C + +I FL+D S S+G NF M
Sbjct: 591 --YYVHDFDALKDIRNQVVQEICTEE--ACKEM---KADIMFLVDSSGSIGPENFSKMKT 643
Query: 389 FVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGD 448
F+ N+ +I +I VQF+ + EF + ++ ++ I + ++ T TG
Sbjct: 644 FMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTLTGS 703
Query: 449 AISFTVRNVFGPIRES-PN-KNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPL 506
A+SF V F P + + PN + FL+++TDG++ D V+ PA G+ I+SVGV + +
Sbjct: 704 ALSF-VSQYFSPTKGARPNIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNV 762
Query: 507 DDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGIC 542
L++++ +P+ F+ F L+ I D++ GIC
Sbjct: 763 TQLEEISGRPE--MVFYVENFDILQRIEDDLVFGIC 796
Score = 153 bits (387), Expect = 3e-37
Identities = 114/389 (29%), Positives = 191/389 (49%), Gaps = 24/389 (6%)
Query: 160 KDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYL 219
K+ KADI FL+D S +IG F+ K F+ + IG + +G+VQ S+ K EF L
Sbjct: 617 KEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQL 676
Query: 220 KNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPS 279
F S D+ AI ++ G + TG AL +Q +F+ G R I K +++ DG
Sbjct: 677 NRFMSQSDISNAIDQMAHIGQTTLTGSALSFVSQ-YFSPTKGARPNIRKFLILITDGEAQ 735
Query: 280 DDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGT 339
D ++E +V R+ GV ++ V V +VT +++ R F ++ N+
Sbjct: 736 DIVKEPAVVLRQEGVIIYSVGV---------FGSNVTQLEEISGRPEMVF--YVENFDIL 784
Query: 340 TKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEI 399
+ LV +C+ + C + +++ F+ID S S+ + +M +F+ + K ++
Sbjct: 785 QRIEDDLVFGICSPRE-ECKR--IEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADV 841
Query: 400 SDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFG 459
+ A+++ D F D+ TK V++V++N + M G T T +A+ F+ ++F
Sbjct: 842 GKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGSTYTAEALGFS-DHMFT 900
Query: 460 PIRESP-NK---NFLVIVTDGQSY--DDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMA 513
R S NK L+++TDG+S+ D + A A D GI + +VG+ A +L MA
Sbjct: 901 EARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVELLAMA 960
Query: 514 SKPKESHAFFTREFTGLEPIVSDVIRGIC 542
FF F GL+ I SDV +C
Sbjct: 961 G--SSDKYFFVETFGGLKGIFSDVTASVC 987
Score = 136 bits (343), Expect = 4e-32
Identities = 109/395 (27%), Positives = 183/395 (46%), Gaps = 23/395 (5%)
Query: 164 ADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFT 223
AD+ FL+D S N + F+ K F+ + L I VGLV S K+ L
Sbjct: 228 ADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGI 287
Query: 224 SAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRK--GIPKVVVVFIDGWPSDD 281
+ +VL I+ + R G + TG A+K ++ F+ G RK G+P++ V+ D+
Sbjct: 288 NKSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTHRDSEDN 347
Query: 282 IEEAGIVAREFGVNVFIVSVAKPIPEELGMVQD----------VTFVDKAVCRNNGFFSY 331
+ +A + R GV +F + + +L + TF D A +N F
Sbjct: 348 VTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAA--HNQTFLK 405
Query: 332 HMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVS 391
+ N T V ++ T + C T +I LIDGS S ++F M F+S
Sbjct: 406 KLRNQI--THTVSVFSERTETLKSG-CVDT--EEADIYLLIDGSGSTQATDFHEMKTFLS 460
Query: 392 NIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAIS 451
+ F I+ ++ AVQ+ EF YS K+++ I NIR M G T TG A++
Sbjct: 461 EVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIENIRQMGGNTNTGAALN 520
Query: 452 FTVRNVFGPIRESPNK--NFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDL 509
FT+ + ++ NK LV++T+G S D + PA + I ++++G+ A L
Sbjct: 521 FTLSLLQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQL 580
Query: 510 KDMASKPKESHAFFTREFTGLEPIVSDVIRGICRD 544
+++A +E ++ +F L+ I + V++ IC +
Sbjct: 581 REIAG--EEKRVYYVHDFDALKDIRNQVVQEICTE 613
Score = 130 bits (326), Expect = 4e-30
Identities = 106/402 (26%), Positives = 188/402 (46%), Gaps = 32/402 (7%)
Query: 160 KDCKA----DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKI 215
++CK D+ F+ID S +I +N+ K+F+ + +G G ++ ++ P++
Sbjct: 800 EECKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEV 859
Query: 216 EFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR--KGIPKVVVVF 273
FYL +F + +V+ ++ GG++ T +AL + FT G R KG+P+V++V
Sbjct: 860 LFYLDDFGTKLEVISVLQNDQAMGGSTYTAEALGFS-DHMFTEARGSRLNKGVPQVLIVI 918
Query: 274 IDG--WPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSY 331
DG +D + R+ G+ V V + P EL + + DK Y
Sbjct: 919 TDGESHDADKLNATAKALRDKGILVLAVGIDGANPVELLAMAGSS--DK----------Y 966
Query: 332 HMPNWFGTTKYV-KPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFV 390
FG K + + +C ++ C + V++ FL+DGS+S+ ++F+ M EF+
Sbjct: 967 FFVETFGGLKGIFSDVTASVCNSSKVDCE---IDKVDLVFLMDGSTSIQPNDFKKMKEFL 1023
Query: 391 SNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAI 450
+++ + F++S +I A QF+ EF + ++ + I NI+ + G T G A+
Sbjct: 1024 ASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQIFGNTHIGAAL 1083
Query: 451 SFTVRNVFGPIRES----PNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPL 506
V + F P S L+++TDGQS D+V A A GI I+SVG+ +
Sbjct: 1084 R-EVEHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGIDIYSVGI--GDV 1140
Query: 507 DDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGICRDFLES 548
DD + + F L+ + ++R IC ES
Sbjct: 1141 DDQQLIQITGTAEKKLTVHNFDELKKVNKRIVRNICTTAGES 1182
Score = 121 bits (304), Expect = 1e-27
Identities = 103/378 (27%), Positives = 165/378 (43%), Gaps = 18/378 (4%)
Query: 164 ADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFT 223
AD+ FL+D S +G + F K F+ K+ L I + V L Q S+ EF+L F
Sbjct: 26 ADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFK 85
Query: 224 SAKDVLFAI-KEVGFRGGNSNTGKALKHTAQKFFTVDAGVR--KGIPKVVVVFIDGWPSD 280
+L + K GF GG+ GKAL+ + +F+ A R K P ++VV D
Sbjct: 86 GRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESED 145
Query: 281 DIEEAGIVAREFGVNVFIVSVAKPIPEEL-GMVQDVTFVDKAVCRNNGFFSYHMPNWFGT 339
++EEA R+ GV + V V K E L M + R+ FS +M
Sbjct: 146 NVEEASKALRKDGVKIISVGVQKASEENLKAMATSQFHFNLRTVRDLSMFSQNM------ 199
Query: 340 TKYVKPLVQKLCTHEQMMCSKTCY--NSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTF 397
T +K +++ + + C + ++ FL+D S + + NF + F+
Sbjct: 200 THIIKDVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSAL 259
Query: 398 EISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNV 457
+I + ++ V ++ + + S + K VL I+N+ +G TG AI + V
Sbjct: 260 DIKENCMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGKAYTGAAIKKLRKEV 319
Query: 458 FGPIRESPNKN-----FLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDM 512
F R KN V+VT S D+V A G+TIF++G+ A L+ +
Sbjct: 320 FS-ARNGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKI 378
Query: 513 ASKPKESHAFFTREFTGL 530
AS P E + + F L
Sbjct: 379 ASHPAEQYVSKLKTFADL 396
Score = 61.2 bits (147), Expect = 2e-09
Identities = 45/182 (24%), Positives = 84/182 (46%), Gaps = 9/182 (4%)
Query: 367 NIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYST 426
++ FL+D S +G +F + F++ + + I ++A Q++ +EF + +
Sbjct: 27 DVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKG 86
Query: 427 KENVLAVIR-NIRYMSGGTATGDAISFTVRNVFG-PIRESPNKNF---LVIVTDGQSYDD 481
+ +L +R N ++ G G A+ R F P K F LV++ +S D+
Sbjct: 87 RSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESEDN 146
Query: 482 VQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFT----GLEPIVSDV 537
V+ + A G+ I SVGV A ++LK MA+ + R+ + + I+ DV
Sbjct: 147 VEEASKALRKDGVKIISVGVQKASEENLKAMATSQFHFNLRTVRDLSMFSQNMTHIIKDV 206
Query: 538 IR 539
I+
Sbjct: 207 IK 208
Score = 47.0 bits (110), Expect = 5e-05
Identities = 80/414 (19%), Positives = 160/414 (38%), Gaps = 71/414 (17%)
Query: 158 GNKDCKA---DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTE----GPHVGLVQAS 210
G +C ++ F +D S ++ ++ F K + + + + G H+ ++ +
Sbjct: 1747 GKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYN 1806
Query: 211 EHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNT--GKALKHTAQKFFTVDAGVRKGIP- 267
H + + +L I+ + + +++ G+A++ ++ F ++ +P
Sbjct: 1807 SHARHLVRFSDAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVF------KRTLPG 1860
Query: 268 ---KVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCR 324
+ + F S D A EFG I P+ V V A+
Sbjct: 1861 AHTRKIATFFSSGQSADAHSITTAAMEFGALEII-----PVVITFSNVPSVRRAF-AIDD 1914
Query: 325 NNGFFSYHMPNWFGTTKYVKPLVQKL--CTHEQMMCSKTC----------YNSVNIAFLI 372
F +P+ Y+ P +++L CT +C + ++ AFL+
Sbjct: 1915 TGTFQVIVVPSG---ADYI-PALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLL 1970
Query: 373 DGSSSVGDSNFRLMLEFVSNIAKTFEI------SDIGAKIAAVQFTYDQ----------R 416
D S ++G + F + F+ + FEI S G ++A + R
Sbjct: 1971 DASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVR 2030
Query: 417 TEFSFTDYSTKENVLA-VIRNIRYMSGGTATGDAISFTVRNVFGPIRESPN--KNFLVIV 473
EF+ T Y +K + V +++ ++G G A+ +T+ NVF +PN +N ++ V
Sbjct: 2031 AEFNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQWTLDNVF---LSTPNLRRNKVIFV 2087
Query: 474 TDGQSYDDVQGP-------AAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESH 520
+ G A + +FS+G W +L+D+AS P + H
Sbjct: 2088 ISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDD-KELEDLASHPLDHH 2140
>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
sapiens]
Length = 3177
Score = 154 bits (388), Expect = 3e-37
Identities = 119/421 (28%), Positives = 190/421 (45%), Gaps = 38/421 (9%)
Query: 144 PTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPH 203
PT ++ + K G ADI FL+D S+ IG+ F L + F+ V L +G H
Sbjct: 21 PTTHAQQQQADVKNG---AAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFH 77
Query: 204 VGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR 263
LVQ + +P EF L + + ++VL I + + GG + TGK L++ Q T AG R
Sbjct: 78 FALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSR 137
Query: 264 --KGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKA 321
G+P+V+VV DG D + + VNVF + V D + +
Sbjct: 138 AGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVED---------ADEGALKEI 188
Query: 322 VCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSK----------TCYNSVNIAFL 371
+++ N+ V LV C H + + T +S +I FL
Sbjct: 189 ASEPLNMHMFNLENFTSLHDIVGNLVS--CVHSSVSPERAGDTETLKDITAQDSADIIFL 246
Query: 372 IDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVL 431
IDGS++ G NF ++L+F+ N+ + I ++ VQF+ + RT FS YSTK VL
Sbjct: 247 IDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVL 306
Query: 432 AVIRNIRYMSGGTAT-GDAISFTVRNVF----GPIRESPNKNFLVIVTDGQSYDDVQGPA 486
++ + + G A G A+ F V N F G E LV+++ G S D+++
Sbjct: 307 GAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGV 366
Query: 487 AAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFT----REFTGLEPIVSDVIRGIC 542
A A + F +G A +L+ +A+ + + FT R F L+ + I G+
Sbjct: 367 VALKQASVFSFGLGAQAASRAELQHIAT---DDNLVFTVPEFRSFGDLQEKLLPYIVGVA 423
Query: 543 R 543
+
Sbjct: 424 Q 424
Score = 144 bits (362), Expect = 3e-34
Identities = 117/401 (29%), Positives = 186/401 (46%), Gaps = 23/401 (5%)
Query: 128 SSTQEATGQAVSTAHPPTG-KRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKN 186
+S + G VS H +R T K ADI FLIDGS N G F + +
Sbjct: 204 TSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILD 263
Query: 187 FVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGN-SNTG 245
F+ + L IGT+ VG+VQ S+ P+ F L +++ VL A+K +GF GG +N G
Sbjct: 264 FLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIG 323
Query: 246 KALKHTAQKFFTVDAG--VRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAK 303
AL + FT G V +G+P+V+V+ G SD+I + ++ V F +
Sbjct: 324 LALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQA 383
Query: 304 PIPEELGMVQDVTFVDKAVCRNNGFFSYH------MPNWFGTTKYVKPLVQKLCTHEQMM 357
EL Q + D V F S+ +P G + + +V K T +
Sbjct: 384 ASRAEL---QHIATDDNLVFTVPEFRSFGDLQEKLLPYIVGVAQ--RHIVLKPPTIVTQV 438
Query: 358 CSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRT 417
N +I FL+DGSS++G +NF + +F++ + + EI ++A Q+ R
Sbjct: 439 IE---VNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRP 495
Query: 418 EFSFTDYSTKENVLAVIRNIRYMSGGTA-TGDAISFTVRNVF----GPIRESPNKNFLVI 472
EF F + TK V+ +R ++ + G TG A+ F N+F G LV+
Sbjct: 496 EFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVL 555
Query: 473 VTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMA 513
+T G+S D++ PA + I F++G A +L+++A
Sbjct: 556 ITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIA 596
Score = 138 bits (347), Expect = 1e-32
Identities = 111/387 (28%), Positives = 181/387 (46%), Gaps = 25/387 (6%)
Query: 163 KADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNF 222
K DI FL+DGS +G FN ++F+ KV L IG + V + Q ++ + EFY
Sbjct: 443 KRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTH 502
Query: 223 TSAKDVLFAIKEVGFRGGNS-NTGKALKHTAQKFFTVDAGVR--KGIPKVVVVFIDGWPS 279
+ ++V+ A++++ G++ TG AL FT AG R +GIPK++V+ G
Sbjct: 503 PTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 562
Query: 280 DDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGT 339
D+I + + + F + EL +++ F V +P F
Sbjct: 563 DEISQPAQELKRSSIMAFAIGNKGADQAEL---EEIAFDSSLV---------FIPAEFRA 610
Query: 340 TKYVKPLVQKLCTHEQMMCSKTCY-NSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFE 398
L L + + + N +I FL+DGS++VG +NF + +FV N+ + +
Sbjct: 611 APLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD 670
Query: 399 ISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSG-GTATGDAISFTVRNV 457
I + ++ VQF+ TEFS Y TK ++L +R ++ G G TG A+S+ N
Sbjct: 671 IGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANH 730
Query: 458 F-----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDM 512
F IRE L+++T GQS D A A AGI F VG + A +L+ +
Sbjct: 731 FTEAGGSRIREHV-PQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQI 789
Query: 513 ASKPKESHAFFTREFTGLEPIVSDVIR 539
A P S + +F+ L + +I+
Sbjct: 790 AFNP--SLVYLMDDFSSLPALPQQLIQ 814
Score = 129 bits (325), Expect = 5e-30
Identities = 106/379 (27%), Positives = 168/379 (44%), Gaps = 12/379 (3%)
Query: 163 KADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNF 222
K D+ FLIDGS + G F + + ++ L +G + V ++Q S+ PK+EF L
Sbjct: 1231 KRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAH 1289
Query: 223 TSAKDVLFAIKEVGFRGGNS-NTGKALKHTAQKFFTVDAGVR--KGIPKVVVVFIDGWPS 279
+S +V A++ + +GG N G AL++ ++ F G R +G+P+ +V+ G
Sbjct: 1290 SSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSD 1349
Query: 280 DDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGT 339
D++++ + ++FGV F ++ EEL + +V S
Sbjct: 1350 DEVDDPAVELKQFGVAPFTIA-RNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPI 1408
Query: 340 TKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEI 399
T +QKL + ++ +I FLID S V F + +FVS I + I
Sbjct: 1409 TTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNI 1468
Query: 400 SDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTA-TGDAISFTVRNVF 458
++ VQF+ D EF Y ++ VL IR +R G TG A+ F RN+F
Sbjct: 1469 GPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLF 1528
Query: 459 ----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMAS 514
G E LV+V G+S DDV A +GI VG +L+ + +
Sbjct: 1529 VKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITN 1588
Query: 515 KPKESHAFFTREFTGLEPI 533
P+ F REF L I
Sbjct: 1589 DPR--LVFTVREFRELPNI 1605
Score = 127 bits (318), Expect = 3e-29
Identities = 101/383 (26%), Positives = 180/383 (46%), Gaps = 30/383 (7%)
Query: 147 KRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGL 206
+ L TPE + K DI FL+DGS N+G+ F ++FV + L IG + VGL
Sbjct: 625 RTLSGTPEVHSN----KRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGL 680
Query: 207 VQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNS-NTGKALKHTAQKFFTVDAG--VR 263
VQ S+ P EF L + + D+L ++++ +GG+ NTG AL + FT G +R
Sbjct: 681 VQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIR 740
Query: 264 KGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVC 323
+ +P+++++ G D +A G+ F V ++ EL + + F
Sbjct: 741 EHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAEL---EQIAF------ 791
Query: 324 RNNGFFSYHMPNWFGTTKYVKPLVQKLCTH-----EQMMCSKTCYNSVNIAFLIDGSSSV 378
N Y M ++ + L+Q L T+ E++ ++ + +I FL DGS+++
Sbjct: 792 --NPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQP-ESKRDILFLFDGSANL 848
Query: 379 GDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIR 438
F ++ +F+ I + G +IA Q++ D + E F ++ +K +L +++ ++
Sbjct: 849 -VGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMK 907
Query: 439 YMSGGTAT-GDAISFTVRNVF----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAG 493
+G G A+ + R +F G E FLV++ G+S D V GPA+ +G
Sbjct: 908 IKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSG 967
Query: 494 ITIFSVGVAWAPLDDLKDMASKP 516
+ F A +L+ + P
Sbjct: 968 VVPFIFQAKNADPAELEQIVLSP 990
Score = 123 bits (308), Expect = 5e-28
Identities = 104/414 (25%), Positives = 187/414 (45%), Gaps = 34/414 (8%)
Query: 138 VSTAHPPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGI 197
+ HP LK + D+ FL+DGS + + F L K FV +V L +
Sbjct: 1002 IGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDV 1060
Query: 198 GTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGG-NSNTGKALKHTAQKFF 256
G + V +VQ S+ + EFYL ++ + +DV+ A++++ GG NTG AL+ +
Sbjct: 1061 GQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNIL 1120
Query: 257 TVDAGVR--KGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQD 314
AG R +G+P++++V DD+ +V + G + + ++ +Q
Sbjct: 1121 VSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGN---ADITEMQT 1177
Query: 315 VTFVDKAVCRNNGFFSYHMPNW--FGTTKYV-KPLVQKLCTHE--------QMMCSKTCY 363
++F+ F+ +P + GT + V V +L E Q + S
Sbjct: 1178 ISFIPD--------FAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVG 1229
Query: 364 NSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTD 423
++ FLIDGS S G F+ + + + ++ ++A +QF+ D + EF
Sbjct: 1230 GKRDVVFLIDGSQSAG-PEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 1288
Query: 424 YSTKENVLAVIRNIRYMSGGTA-TGDAISFTVRNVF----GPIRESPNKNFLVIVTDGQS 478
+S+K+ V ++ +R G G+A+ + RN+F G E FLV+++ G+S
Sbjct: 1289 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKS 1348
Query: 479 YDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFT-REFTGLE 531
D+V PA G+ F++ A ++L ++ P+ + T RE LE
Sbjct: 1349 DDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLE 1401
Score = 95.5 bits (236), Expect = 1e-19
Identities = 106/420 (25%), Positives = 177/420 (42%), Gaps = 53/420 (12%)
Query: 137 AVSTAHPPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLG 196
A + A P PEKK KADI FL+DGS N + F FV ++ +
Sbjct: 1617 AATPAPPGVDTPPPSRPEKK------KADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVY 1670
Query: 197 IGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGG-NSNTGKALKHTAQKF 255
+ VGLVQ + P EF+LK+F++ + ++ AI +V ++GG ++NT L+H
Sbjct: 1671 EDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNH 1730
Query: 256 FTVDAGVR--KGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQ 313
F +AG R + +P++ V G +D ++ + + GV VF V V EE+G +
Sbjct: 1731 FVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKI- 1789
Query: 314 DVTFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKL--CTHEQMM-----CSKTCYNSV 366
+N ++ + N ++ + +++ L HE + +K C V
Sbjct: 1790 ----------ASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDV 1839
Query: 367 NIAFLIDGSSS----VGDSNFRLMLEFVSN-IAKTFEISDIGAKIAAVQFTYDQRT---- 417
+ F DGS V F ++ + N I++ +S G + V+ + T
Sbjct: 1840 ILGF--DGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGP 1897
Query: 418 --EFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIV-- 473
F F +Y + +L RN+R T D T++ R+S + V++
Sbjct: 1898 VEAFDFDEY--QPEMLEKFRNMRSQHPYVLTED----TLKVYLNKFRQSSPDSVKVVIHF 1951
Query: 474 TDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPI 533
TDG G A H A + GV L L+ + + + H F R F P+
Sbjct: 1952 TDG-----ADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPL 2006
Score = 47.4 bits (111), Expect = 3e-05
Identities = 33/125 (26%), Positives = 61/125 (48%), Gaps = 20/125 (16%)
Query: 366 VNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIG------AKIAAVQFTYDQ---- 415
+++AF++D + + F M ++++ + + ++S A++A VQ +
Sbjct: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2677
Query: 416 ------RTEFSFTDYSTKENVLAVI-RNIRYMSGGTATGDAISFTVRNVFGPIRESPNKN 468
+ EFS TDY +KE ++ + R + + G A G AI +T+ NVF +PN
Sbjct: 2678 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVF---ESAPNPR 2734
Query: 469 FLVIV 473
L IV
Sbjct: 2735 DLKIV 2739
Score = 43.5 bits (101), Expect = 5e-04
Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Query: 368 IAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDI----GAKIAAVQFTYDQRTEFSFTD 423
+AF +D S V F M + V +I I++ GA++A V + + TE F D
Sbjct: 2403 LAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFAD 2462
Query: 424 YSTKENVLAVIRNIR--YMSGGTATGDAISFTVRNVFGPIR 462
K +L I+N++ S + A+SF RN F +R
Sbjct: 2463 SKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVR 2503
Score = 33.5 bits (75), Expect = 0.52
Identities = 32/150 (21%), Positives = 62/150 (41%), Gaps = 20/150 (13%)
Query: 154 EKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTE---GPHVGLVQAS 210
+++ D D+AF++D + +FN K ++ + L + + H V
Sbjct: 2608 DRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVV 2667
Query: 211 EHP-------------KIEFYLKNFTSAKDVL-FAIKEVGFRGGNSNTGKALKHTAQKFF 256
+H K+EF L ++ S + ++ F + + G G A+++T + F
Sbjct: 2668 QHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVF 2727
Query: 257 TVDAGVRKGIPKVVVVFIDG-WPSDDIEEA 285
R K+VV+ + G P +EEA
Sbjct: 2728 ESAPNPRD--LKIVVLMLTGEVPEQQLEEA 2755
>gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]
Length = 2526
Score = 147 bits (372), Expect = 2e-35
Identities = 112/397 (28%), Positives = 198/397 (49%), Gaps = 20/397 (5%)
Query: 160 KDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYL 219
KD AD+ FL+D S G +LQ F+ + + + +GL+ S K +L
Sbjct: 231 KDSLADLVFLVDESLGTGGNLRHLQ-TFLENITSSMDVKENCMRLGLMSYSNSAKTISFL 289
Query: 220 KNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRK--GIPKVVVVFIDGW 277
K+ T+ + IK + + G SNTG A+ + F+ G R+ G+P++ V+
Sbjct: 290 KSSTTQSEFQQQIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSRRAQGVPQIAVLVTHRP 349
Query: 278 PSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWF 337
D++ +A + R VNVF +S+ +L + V++ + + SY +
Sbjct: 350 SDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEI--VSYPPEQTI--STLKSYADLETY 405
Query: 338 GTTKYVKPLVQKLCTH-----EQMMCSKT-CYNS--VNIAFLIDGSSSVGDSNFRLMLEF 389
+TK++K L ++ + EQ KT C ++ +I FLIDGSSS+ + F + F
Sbjct: 406 -STKFLKKLQNEIWSQISTYAEQRNLDKTGCVDTKEADIHFLIDGSSSIQEKQFEQIKRF 464
Query: 390 VSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDA 449
+ + + F I ++ VQ++ D EF TDYS ++ I NI+ ++GGT TG A
Sbjct: 465 MLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSNDIDLRKAIFNIKQLTGGTYTGKA 524
Query: 450 ISFTVRNVFGPIRESPNK--NFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLD 507
+ + ++ + +++ +K +L+++TDG S D V PA IT+ +VG+ A
Sbjct: 525 LDYILQIIKNGMKDRMSKVPCYLIVLTDGMSTDRVVEPAKRLRAEQITVHAVGIGAANKI 584
Query: 508 DLKDMASKPKESHAFFTREFTGLEPIVSDVIRGICRD 544
+L+++A KE F + F L+ I ++V+R IC +
Sbjct: 585 ELQEIAG--KEERVSFGQNFDALKSIKNEVVREICAE 619
Score = 146 bits (368), Expect = 5e-35
Identities = 117/392 (29%), Positives = 188/392 (47%), Gaps = 26/392 (6%)
Query: 156 KTGNKDCK-ADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPK 214
KTG D K ADI FLIDGS +I +++F K F+ +V M IG + VG+VQ S+ +
Sbjct: 432 KTGCVDTKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTE 491
Query: 215 IEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFI 274
+EFY+ ++++ D+ AI + G + TGKAL + Q +P ++V
Sbjct: 492 VEFYITDYSNDIDLRKAIFNIKQLTGGTYTGKALDYILQIIKNGMKDRMSKVPCYLIVLT 551
Query: 275 DGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMP 334
DG +D + E R + V V + EL Q++ ++ V
Sbjct: 552 DGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIEL---QEIAGKEERVSFGQN------- 601
Query: 335 NWFGTTKYVK-PLVQKLCTHEQMMCSKTCYN-SVNIAFLIDGSSSVGDSNFRLMLEFVSN 392
F K +K +V+++C K C + +I FL+D S S+G+ NFR M F+ N
Sbjct: 602 --FDALKSIKNEVVREIC------AEKGCEDMKADIMFLVDSSWSIGNENFRKMKIFMKN 653
Query: 393 IAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISF 452
+ +I +I VQF+ + EF Y T++ + I + ++ GT TG A++F
Sbjct: 654 LLTKIQIGADKTQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLTGKALNF 713
Query: 453 TVRNVFGPIRES--PNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLK 510
V F + + K FL+++TDG + DDV+ PA +TIFSVGV A L+
Sbjct: 714 -VGQYFTHSKGARLGAKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLE 772
Query: 511 DMASKPKESHAFFTREFTGLEPIVSDVIRGIC 542
+++ S F F L+ + +I +C
Sbjct: 773 EISG--DSSLVFHVENFDHLKALERKLIFRVC 802
Score = 111 bits (278), Expect = 1e-24
Identities = 97/378 (25%), Positives = 163/378 (43%), Gaps = 13/378 (3%)
Query: 164 ADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFT 223
AD+ FL+D S ++G + F K F+ K+ L I V L Q S+ EF+L F
Sbjct: 29 ADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTFK 88
Query: 224 SAKDVLFAIKE-VGFRGGNSNTGKALKHTAQKFFT--VDAGVRKGIPKVVVVFIDGWPSD 280
+L +K+ F GG+ GKAL+ + +F+ ++ RK P ++VV D
Sbjct: 89 GRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVVLASAESED 148
Query: 281 DIEEAGIVAREFGVNVFIVSVAKPIPEEL-GMVQDVTFVDKAVCRNNGFFSYHMPNWF-G 338
++EEA ++ GV + V V K E L M + R+ FS +M
Sbjct: 149 EVEEASKALQKDGVKIISVGVQKASEENLKAMATSHFHFNLRTIRDLSTFSQNMTQIIKD 208
Query: 339 TTKYVKPLVQ-KLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTF 397
TKY + V + H + C K + ++ FL+D S G N R + F+ NI +
Sbjct: 209 VTKYKEGAVDADMQVHFPISCQKD--SLADLVFLVDESLGTG-GNLRHLQTFLENITSSM 265
Query: 398 EISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNV 457
++ + ++ + ++ +T +T+ I+N+ G + TG AI R+
Sbjct: 266 DVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKSNTGAAIDQMRRDG 325
Query: 458 F----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMA 513
F G R V+VT S D+V A + +F++ + A L+++
Sbjct: 326 FSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEIV 385
Query: 514 SKPKESHAFFTREFTGLE 531
S P E + + LE
Sbjct: 386 SYPPEQTISTLKSYADLE 403
Score = 111 bits (277), Expect = 2e-24
Identities = 111/440 (25%), Positives = 191/440 (43%), Gaps = 40/440 (9%)
Query: 127 KSSTQEATGQAVSTAHPPTGKRLKKTPEKKTGN----KDCKA----DIAFLIDGSFNIGQ 178
+S +E +G + H LK K DCK D+ F++D S +I +
Sbjct: 768 RSQLEEISGDSSLVFHVENFDHLKALERKLIFRVCALHDCKRITLLDVVFVLDHSGSIKK 827
Query: 179 RRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFR 238
+ + N + +G + G ++ S+ P I FYL +++ ++ +++
Sbjct: 828 QYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRRDT 887
Query: 239 GGNSNTGKALKHTAQKFFTVDAG--VRKGIPKVVVVFIDG--WPSDDIEEAGIVAREFGV 294
GGN+ T KALKH A FT + G +++ + ++++V DG D + + + R G+
Sbjct: 888 GGNTYTAKALKH-ANALFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKGI 946
Query: 295 NVFIVSVAKPIPEEL-GMVQDVTFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQ-KLCT 352
+F V V K +EL GM + +NN + + F K V LVQ ++CT
Sbjct: 947 TIFAVGVGKANQKELEGMAGN---------KNNTIYVDN----FDKLKDVFTLVQERMCT 993
Query: 353 HEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFT 412
+C ++ FL DGS V +S+F M F+S++ F+I KI QF
Sbjct: 994 EAPEVCH---LQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFG 1050
Query: 413 YDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVF----GPIRESPNKN 468
+ ++ + TK I+N+ SGG D V N+F G R +
Sbjct: 1051 SNYQSIIELKNSLTKTQWKTQIQNVS-KSGGFPRIDFALKKVSNMFNLHAGGRRNAGVPQ 1109
Query: 469 FLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFT 528
LV++T G DV D GI + +G+ + L + ++ F ++F
Sbjct: 1110 TLVVITSGDPRYDVADAVKTLKDLGICVLVLGIGDVYKEHLLPITGNSEKIITF--QDFD 1167
Query: 529 GLEPIVSDVIRGICRDFLES 548
L+ + DV + I R+ +S
Sbjct: 1168 KLKNV--DVKKRIIREICQS 1185
Score = 63.9 bits (154), Expect = 4e-10
Identities = 42/182 (23%), Positives = 87/182 (47%), Gaps = 5/182 (2%)
Query: 367 NIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYST 426
++ FL+D S +G +F + F++ + + I ++A Q++ + +EF + +
Sbjct: 30 DVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTFKG 89
Query: 427 KENVLAVIR-NIRYMSGGTATGDAISFTVRNVFG-PIRESPNKNF---LVIVTDGQSYDD 481
+ +L ++ N +++ G G A+ R F PI K F LV++ +S D+
Sbjct: 90 RSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVVLASAESEDE 149
Query: 482 VQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGI 541
V+ + A G+ I SVGV A ++LK MA+ + R+ + ++ +I+ +
Sbjct: 150 VEEASKALQKDGVKIISVGVQKASEENLKAMATSHFHFNLRTIRDLSTFSQNMTQIIKDV 209
Query: 542 CR 543
+
Sbjct: 210 TK 211
Score = 48.5 bits (114), Expect = 2e-05
Identities = 44/176 (25%), Positives = 81/176 (46%), Gaps = 21/176 (11%)
Query: 366 VNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEI------SDIGAKIAAVQFT---YDQR 416
+++AFLID S VG F+ + F++++ F I S +G ++A + ++ Y
Sbjct: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349
Query: 417 T-------EFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVF-GPIRESPNKN 468
T EF Y++ + +++ + ++G G A+ +T+ NVF G NK
Sbjct: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKNKV 2409
Query: 469 FLVI---VTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLD-DLKDMASKPKESH 520
VI T+ D ++ + A G +IF D +L+++AS P + H
Sbjct: 2410 IFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASHPLDHH 2465
Score = 43.5 bits (101), Expect = 5e-04
Identities = 32/140 (22%), Positives = 61/140 (43%), Gaps = 7/140 (5%)
Query: 346 LVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISD---- 401
L++ L H K + F +D S V + +F + +++I I +
Sbjct: 1737 LIRFLREHSPCWKEKCPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCP 1796
Query: 402 IGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYM--SGGTATGDAISFTVRNVFG 459
+GA++A V + ++DY+ K+ +L + I+Y + G+A+ F RNVF
Sbjct: 1797 VGARVAMVSYNSGTSYLIRWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFK 1856
Query: 460 PIRESPN-KNFLVIVTDGQS 478
N + V ++GQ+
Sbjct: 1857 RTYAGANVRRVAVFFSNGQT 1876
Score = 38.1 bits (87), Expect = 0.021
Identities = 66/286 (23%), Positives = 107/286 (37%), Gaps = 48/286 (16%)
Query: 97 GREN-YSSVDANG------IQSQMLSRWSASFTVTKGKSSTQEATGQAVSTAHPPTGKRL 149
GRE+ + + NG + SQM K + S + A+ +++ H G++
Sbjct: 2216 GRESPFVKTEDNGSDYLVYLPSQMFEPQKLMINYEKDQKSAEIAS---LTSGHENYGRKE 2272
Query: 150 KKTPEKKTGN---KDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGI------GTE 200
+ + G+ ++ D+AFLID S +G F K F+ V I T
Sbjct: 2273 EPDHTYEPGDVSLQEYYMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTL 2332
Query: 201 GPHVGLVQAS---------EHP-KIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKH 250
G V ++ S E P +EF L + S + +++ G+ G AL+
Sbjct: 2333 GDRVAVLSYSPPGYMPNTEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQW 2392
Query: 251 TAQKFFTVDAGVRKGIPKVVVVFIDG----WPSDDIEEAGIVAREFGVNVFIVSVA---- 302
T F +RK KV+ V G D + + A+ G ++F+ S
Sbjct: 2393 TIDNVFVGTPNLRKN--KVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHN 2450
Query: 303 -KPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLV 347
K + E D V H P+W K+VKP V
Sbjct: 2451 DKELEELASHPLDHHLVQLG--------RTHKPDWNYIIKFVKPFV 2488
>gi|13699836 matrilin 4 isoform 3 precursor [Homo sapiens]
Length = 499
Score = 145 bits (367), Expect = 7e-35
Identities = 108/426 (25%), Positives = 185/426 (43%), Gaps = 64/426 (15%)
Query: 165 DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTS 224
D+ F+ID S ++ F + F+ + L +G VG++Q S + F L+ F+
Sbjct: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
Query: 225 AKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR---KGIPKVVVVFIDGWPSDD 281
+D+ AI+++ + TG A+++ F+V G R + +P+V V+ DG P D
Sbjct: 94 REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
Query: 282 IEEAGIVAREFGVNVFIVSVAK------------PIPEELGMVQDVTFVDKAVCRNNGFF 329
+ E AR G+ ++ V V + P+ E + +V+ + +
Sbjct: 154 VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQE--------- 204
Query: 330 SYHMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCYNS------------------------ 365
FG + V+ LC C C +
Sbjct: 205 -------FGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRC 257
Query: 366 ----VNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSF 421
V++ L+DGS SV NF L+ FV+ I ++S G ++ VQF+ RTEF
Sbjct: 258 REGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPL 317
Query: 422 TDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLV-----IVTDG 476
Y T V + + YM GT TG A+ V + F + + + V + TDG
Sbjct: 318 GRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDG 377
Query: 477 QSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSD 536
+S DD+ AA A + GI +++VGV A +L+++AS+P E H + +F + ++ +
Sbjct: 378 RSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLEN 437
Query: 537 VIRGIC 542
+ IC
Sbjct: 438 LRGSIC 443
Score = 89.4 bits (220), Expect = 8e-18
Identities = 54/169 (31%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 144 PTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPH 203
P G++L+ + ++ D+ L+DGS ++ + F L K FV ++ L + EG
Sbjct: 242 PEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTR 301
Query: 204 VGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR 263
VGLVQ S + EF L + +A +V A+ V + + TG AL+H + F+ G R
Sbjct: 302 VGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGAR 361
Query: 264 K---GIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEEL 309
+P+V +VF DG DDI A+E G+ ++ V V K + EL
Sbjct: 362 PRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAEL 410
Score = 81.6 bits (200), Expect = 2e-15
Identities = 53/187 (28%), Positives = 88/187 (47%), Gaps = 5/187 (2%)
Query: 346 LVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAK 405
L+Q T Q+ + +++ F+ID S SV F M +F+ + + + +
Sbjct: 13 LLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATR 72
Query: 406 IAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIR--- 462
+ +Q++ ++ F +S +E++ IR++ ++ GT TG AI + + F
Sbjct: 73 VGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGAR 132
Query: 463 --ESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESH 520
E VIVTDG+ D V AA A GI I++VGV A + L+ MAS P + H
Sbjct: 133 PPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEH 192
Query: 521 AFFTREF 527
F F
Sbjct: 193 VFLVESF 199
>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
sapiens]
Length = 2971
Score = 140 bits (352), Expect = 4e-33
Identities = 109/364 (29%), Positives = 176/364 (48%), Gaps = 22/364 (6%)
Query: 164 ADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFT 223
ADI FLIDGS N G F + +F+ + L IGT+ VG+VQ S+ P+ F L ++
Sbjct: 35 ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYS 94
Query: 224 SAKDVLFAIKEVGFRGGN-SNTGKALKHTAQKFFTVDAG--VRKGIPKVVVVFIDGWPSD 280
+ VL A+K +GF GG +N G AL + FT G V +G+P+V+V+ G SD
Sbjct: 95 TKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSD 154
Query: 281 DIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYH------MP 334
+I + ++ V F + EL Q + D V F S+ +P
Sbjct: 155 EIRYGVVALKQASVFSFGLGAQAASRAEL---QHIATDDNLVFTVPEFRSFGDLQEKLLP 211
Query: 335 NWFGTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIA 394
G + + +V K T ++ N +I FL+DGSS++G +NF + +F++ +
Sbjct: 212 YIVGVAQ--RHIVLKPPT---IVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVI 266
Query: 395 KTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTA-TGDAISFT 453
+ EI ++A Q+ R EF F + TK V+ +R ++ + G TG A+ F
Sbjct: 267 QRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFV 326
Query: 454 VRNVF----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDL 509
N+F G LV++T G+S D++ PA + I F++G A +L
Sbjct: 327 RNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAEL 386
Query: 510 KDMA 513
+++A
Sbjct: 387 EEIA 390
Score = 138 bits (347), Expect = 1e-32
Identities = 111/387 (28%), Positives = 181/387 (46%), Gaps = 25/387 (6%)
Query: 163 KADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNF 222
K DI FL+DGS +G FN ++F+ KV L IG + V + Q ++ + EFY
Sbjct: 237 KRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTH 296
Query: 223 TSAKDVLFAIKEVGFRGGNS-NTGKALKHTAQKFFTVDAGVR--KGIPKVVVVFIDGWPS 279
+ ++V+ A++++ G++ TG AL FT AG R +GIPK++V+ G
Sbjct: 297 PTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 356
Query: 280 DDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGT 339
D+I + + + F + EL +++ F V +P F
Sbjct: 357 DEISQPAQELKRSSIMAFAIGNKGADQAEL---EEIAFDSSLV---------FIPAEFRA 404
Query: 340 TKYVKPLVQKLCTHEQMMCSKTCY-NSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFE 398
L L + + + N +I FL+DGS++VG +NF + +FV N+ + +
Sbjct: 405 APLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD 464
Query: 399 ISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSG-GTATGDAISFTVRNV 457
I + ++ VQF+ TEFS Y TK ++L +R ++ G G TG A+S+ N
Sbjct: 465 IGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANH 524
Query: 458 F-----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDM 512
F IRE L+++T GQS D A A AGI F VG + A +L+ +
Sbjct: 525 FTEAGGSRIREHV-PQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQI 583
Query: 513 ASKPKESHAFFTREFTGLEPIVSDVIR 539
A P S + +F+ L + +I+
Sbjct: 584 AFNP--SLVYLMDDFSSLPALPQQLIQ 608
Score = 129 bits (325), Expect = 5e-30
Identities = 106/379 (27%), Positives = 168/379 (44%), Gaps = 12/379 (3%)
Query: 163 KADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNF 222
K D+ FLIDGS + G F + + ++ L +G + V ++Q S+ PK+EF L
Sbjct: 1025 KRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAH 1083
Query: 223 TSAKDVLFAIKEVGFRGGNS-NTGKALKHTAQKFFTVDAGVR--KGIPKVVVVFIDGWPS 279
+S +V A++ + +GG N G AL++ ++ F G R +G+P+ +V+ G
Sbjct: 1084 SSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSD 1143
Query: 280 DDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGT 339
D++++ + ++FGV F ++ EEL + +V S
Sbjct: 1144 DEVDDPAVELKQFGVAPFTIA-RNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPI 1202
Query: 340 TKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEI 399
T +QKL + ++ +I FLID S V F + +FVS I + I
Sbjct: 1203 TTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNI 1262
Query: 400 SDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTA-TGDAISFTVRNVF 458
++ VQF+ D EF Y ++ VL IR +R G TG A+ F RN+F
Sbjct: 1263 GPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLF 1322
Query: 459 ----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMAS 514
G E LV+V G+S DDV A +GI VG +L+ + +
Sbjct: 1323 VKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITN 1382
Query: 515 KPKESHAFFTREFTGLEPI 533
P+ F REF L I
Sbjct: 1383 DPR--LVFTVREFRELPNI 1399
Score = 127 bits (318), Expect = 3e-29
Identities = 101/383 (26%), Positives = 180/383 (46%), Gaps = 30/383 (7%)
Query: 147 KRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGL 206
+ L TPE + K DI FL+DGS N+G+ F ++FV + L IG + VGL
Sbjct: 419 RTLSGTPEVHSN----KRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGL 474
Query: 207 VQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNS-NTGKALKHTAQKFFTVDAG--VR 263
VQ S+ P EF L + + D+L ++++ +GG+ NTG AL + FT G +R
Sbjct: 475 VQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIR 534
Query: 264 KGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVC 323
+ +P+++++ G D +A G+ F V ++ EL + + F
Sbjct: 535 EHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAEL---EQIAF------ 585
Query: 324 RNNGFFSYHMPNWFGTTKYVKPLVQKLCTH-----EQMMCSKTCYNSVNIAFLIDGSSSV 378
N Y M ++ + L+Q L T+ E++ ++ + +I FL DGS+++
Sbjct: 586 --NPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQP-ESKRDILFLFDGSANL 642
Query: 379 GDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIR 438
F ++ +F+ I + G +IA Q++ D + E F ++ +K +L +++ ++
Sbjct: 643 -VGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMK 701
Query: 439 YMSGGTAT-GDAISFTVRNVF----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAG 493
+G G A+ + R +F G E FLV++ G+S D V GPA+ +G
Sbjct: 702 IKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSG 761
Query: 494 ITIFSVGVAWAPLDDLKDMASKP 516
+ F A +L+ + P
Sbjct: 762 VVPFIFQAKNADPAELEQIVLSP 784
Score = 123 bits (308), Expect = 5e-28
Identities = 104/414 (25%), Positives = 187/414 (45%), Gaps = 34/414 (8%)
Query: 138 VSTAHPPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGI 197
+ HP LK + D+ FL+DGS + + F L K FV +V L +
Sbjct: 796 IGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDV 854
Query: 198 GTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGG-NSNTGKALKHTAQKFF 256
G + V +VQ S+ + EFYL ++ + +DV+ A++++ GG NTG AL+ +
Sbjct: 855 GQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNIL 914
Query: 257 TVDAGVR--KGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQD 314
AG R +G+P++++V DD+ +V + G + + ++ +Q
Sbjct: 915 VSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGN---ADITEMQT 971
Query: 315 VTFVDKAVCRNNGFFSYHMPNW--FGTTKYV-KPLVQKLCTHE--------QMMCSKTCY 363
++F+ F+ +P + GT + V V +L E Q + S
Sbjct: 972 ISFIPD--------FAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVG 1023
Query: 364 NSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTD 423
++ FLIDGS S G F+ + + + ++ ++A +QF+ D + EF
Sbjct: 1024 GKRDVVFLIDGSQSAG-PEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 1082
Query: 424 YSTKENVLAVIRNIRYMSGGTA-TGDAISFTVRNVF----GPIRESPNKNFLVIVTDGQS 478
+S+K+ V ++ +R G G+A+ + RN+F G E FLV+++ G+S
Sbjct: 1083 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKS 1142
Query: 479 YDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFT-REFTGLE 531
D+V PA G+ F++ A ++L ++ P+ + T RE LE
Sbjct: 1143 DDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLE 1195
Score = 95.5 bits (236), Expect = 1e-19
Identities = 106/420 (25%), Positives = 177/420 (42%), Gaps = 53/420 (12%)
Query: 137 AVSTAHPPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLG 196
A + A P PEKK KADI FL+DGS N + F FV ++ +
Sbjct: 1411 AATPAPPGVDTPPPSRPEKK------KADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVY 1464
Query: 197 IGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGG-NSNTGKALKHTAQKF 255
+ VGLVQ + P EF+LK+F++ + ++ AI +V ++GG ++NT L+H
Sbjct: 1465 EDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNH 1524
Query: 256 FTVDAGVR--KGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQ 313
F +AG R + +P++ V G +D ++ + + GV VF V V EE+G +
Sbjct: 1525 FVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKI- 1583
Query: 314 DVTFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKL--CTHEQMM-----CSKTCYNSV 366
+N ++ + N ++ + +++ L HE + +K C V
Sbjct: 1584 ----------ASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDV 1633
Query: 367 NIAFLIDGSSS----VGDSNFRLMLEFVSN-IAKTFEISDIGAKIAAVQFTYDQRT---- 417
+ F DGS V F ++ + N I++ +S G + V+ + T
Sbjct: 1634 ILGF--DGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGP 1691
Query: 418 --EFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIV-- 473
F F +Y + +L RN+R T D T++ R+S + V++
Sbjct: 1692 VEAFDFDEY--QPEMLEKFRNMRSQHPYVLTED----TLKVYLNKFRQSSPDSVKVVIHF 1745
Query: 474 TDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPI 533
TDG G A H A + GV L L+ + + + H F R F P+
Sbjct: 1746 TDG-----ADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPL 1800
Score = 82.4 bits (202), Expect = 1e-15
Identities = 64/216 (29%), Positives = 102/216 (47%), Gaps = 22/216 (10%)
Query: 345 PLVQKLC--------THEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKT 396
PLV C TH Q + +S +I FLIDGS++ G NF ++L+F+ N+ +
Sbjct: 8 PLVAVFCLFLSGFPTTHAQQQ--QAAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEK 65
Query: 397 FEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTAT-GDAISFTVR 455
I ++ VQF+ + RT FS YSTK VL ++ + + G A G A+ F V
Sbjct: 66 LPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVE 125
Query: 456 NVF----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKD 511
N F G E LV+++ G S D+++ A A + F +G A +L+
Sbjct: 126 NHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQH 185
Query: 512 MASKPKESHAFFT----REFTGLEPIVSDVIRGICR 543
+A+ + + FT R F L+ + I G+ +
Sbjct: 186 IAT---DDNLVFTVPEFRSFGDLQEKLLPYIVGVAQ 218
Score = 47.4 bits (111), Expect = 3e-05
Identities = 33/125 (26%), Positives = 61/125 (48%), Gaps = 20/125 (16%)
Query: 366 VNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIG------AKIAAVQFTYDQ---- 415
+++AF++D + + F M ++++ + + ++S A++A VQ +
Sbjct: 2412 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2471
Query: 416 ------RTEFSFTDYSTKENVLAVI-RNIRYMSGGTATGDAISFTVRNVFGPIRESPNKN 468
+ EFS TDY +KE ++ + R + + G A G AI +T+ NVF +PN
Sbjct: 2472 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVF---ESAPNPR 2528
Query: 469 FLVIV 473
L IV
Sbjct: 2529 DLKIV 2533
Score = 43.5 bits (101), Expect = 5e-04
Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Query: 368 IAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDI----GAKIAAVQFTYDQRTEFSFTD 423
+AF +D S V F M + V +I I++ GA++A V + + TE F D
Sbjct: 2197 LAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFAD 2256
Query: 424 YSTKENVLAVIRNIR--YMSGGTATGDAISFTVRNVFGPIR 462
K +L I+N++ S + A+SF RN F +R
Sbjct: 2257 SKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVR 2297
Score = 33.5 bits (75), Expect = 0.52
Identities = 32/150 (21%), Positives = 62/150 (41%), Gaps = 20/150 (13%)
Query: 154 EKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTE---GPHVGLVQAS 210
+++ D D+AF++D + +FN K ++ + L + + H V
Sbjct: 2402 DRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVV 2461
Query: 211 EHP-------------KIEFYLKNFTSAKDVL-FAIKEVGFRGGNSNTGKALKHTAQKFF 256
+H K+EF L ++ S + ++ F + + G G A+++T + F
Sbjct: 2462 QHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVF 2521
Query: 257 TVDAGVRKGIPKVVVVFIDG-WPSDDIEEA 285
R K+VV+ + G P +EEA
Sbjct: 2522 ESAPNPRD--LKIVVLMLTGEVPEQQLEEA 2549
>gi|240255540 alpha 3 type VI collagen isoform 3 precursor [Homo
sapiens]
Length = 1237
Score = 140 bits (352), Expect = 4e-33
Identities = 109/364 (29%), Positives = 176/364 (48%), Gaps = 22/364 (6%)
Query: 164 ADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFT 223
ADI FLIDGS N G F + +F+ + L IGT+ VG+VQ S+ P+ F L ++
Sbjct: 35 ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYS 94
Query: 224 SAKDVLFAIKEVGFRGGN-SNTGKALKHTAQKFFTVDAG--VRKGIPKVVVVFIDGWPSD 280
+ VL A+K +GF GG +N G AL + FT G V +G+P+V+V+ G SD
Sbjct: 95 TKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSD 154
Query: 281 DIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYH------MP 334
+I + ++ V F + EL Q + D V F S+ +P
Sbjct: 155 EIRYGVVALKQASVFSFGLGAQAASRAEL---QHIATDDNLVFTVPEFRSFGDLQEKLLP 211
Query: 335 NWFGTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIA 394
G + + +V K T ++ N +I FL+DGSS++G +NF + +F++ +
Sbjct: 212 YIVGVAQ--RHIVLKPPT---IVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVI 266
Query: 395 KTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTA-TGDAISFT 453
+ EI ++A Q+ R EF F + TK V+ +R ++ + G TG A+ F
Sbjct: 267 QRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFV 326
Query: 454 VRNVF----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDL 509
N+F G LV++T G+S D++ PA + I F++G A +L
Sbjct: 327 RNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAEL 386
Query: 510 KDMA 513
+++A
Sbjct: 387 EEIA 390
Score = 138 bits (347), Expect = 1e-32
Identities = 111/387 (28%), Positives = 181/387 (46%), Gaps = 25/387 (6%)
Query: 163 KADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNF 222
K DI FL+DGS +G FN ++F+ KV L IG + V + Q ++ + EFY
Sbjct: 237 KRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTH 296
Query: 223 TSAKDVLFAIKEVGFRGGNS-NTGKALKHTAQKFFTVDAGVR--KGIPKVVVVFIDGWPS 279
+ ++V+ A++++ G++ TG AL FT AG R +GIPK++V+ G
Sbjct: 297 PTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 356
Query: 280 DDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGT 339
D+I + + + F + EL +++ F V +P F
Sbjct: 357 DEISQPAQELKRSSIMAFAIGNKGADQAEL---EEIAFDSSLV---------FIPAEFRA 404
Query: 340 TKYVKPLVQKLCTHEQMMCSKTCY-NSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFE 398
L L + + + N +I FL+DGS++VG +NF + +FV N+ + +
Sbjct: 405 APLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD 464
Query: 399 ISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSG-GTATGDAISFTVRNV 457
I + ++ VQF+ TEFS Y TK ++L +R ++ G G TG A+S+ N
Sbjct: 465 IGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANH 524
Query: 458 F-----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDM 512
F IRE L+++T GQS D A A AGI F VG + A +L+ +
Sbjct: 525 FTEAGGSRIREHV-PQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQI 583
Query: 513 ASKPKESHAFFTREFTGLEPIVSDVIR 539
A P S + +F+ L + +I+
Sbjct: 584 AFNP--SLVYLMDDFSSLPALPQQLIQ 608
Score = 127 bits (318), Expect = 3e-29
Identities = 101/383 (26%), Positives = 180/383 (46%), Gaps = 30/383 (7%)
Query: 147 KRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGL 206
+ L TPE + K DI FL+DGS N+G+ F ++FV + L IG + VGL
Sbjct: 419 RTLSGTPEVHSN----KRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGL 474
Query: 207 VQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNS-NTGKALKHTAQKFFTVDAG--VR 263
VQ S+ P EF L + + D+L ++++ +GG+ NTG AL + FT G +R
Sbjct: 475 VQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIR 534
Query: 264 KGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVC 323
+ +P+++++ G D +A G+ F V ++ EL + + F
Sbjct: 535 EHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAEL---EQIAF------ 585
Query: 324 RNNGFFSYHMPNWFGTTKYVKPLVQKLCTH-----EQMMCSKTCYNSVNIAFLIDGSSSV 378
N Y M ++ + L+Q L T+ E++ ++ + +I FL DGS+++
Sbjct: 586 --NPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQP-ESKRDILFLFDGSANL 642
Query: 379 GDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIR 438
F ++ +F+ I + G +IA Q++ D + E F ++ +K +L +++ ++
Sbjct: 643 -VGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMK 701
Query: 439 YMSGGTAT-GDAISFTVRNVF----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAG 493
+G G A+ + R +F G E FLV++ G+S D V GPA+ +G
Sbjct: 702 IKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSG 761
Query: 494 ITIFSVGVAWAPLDDLKDMASKP 516
+ F A +L+ + P
Sbjct: 762 VVPFIFQAKNADPAELEQIVLSP 784
Score = 123 bits (308), Expect = 5e-28
Identities = 104/414 (25%), Positives = 187/414 (45%), Gaps = 34/414 (8%)
Query: 138 VSTAHPPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGI 197
+ HP LK + D+ FL+DGS + + F L K FV +V L +
Sbjct: 796 IGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDV 854
Query: 198 GTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGG-NSNTGKALKHTAQKFF 256
G + V +VQ S+ + EFYL ++ + +DV+ A++++ GG NTG AL+ +
Sbjct: 855 GQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNIL 914
Query: 257 TVDAGVR--KGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQD 314
AG R +G+P++++V DD+ +V + G + + ++ +Q
Sbjct: 915 VSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGN---ADITEMQT 971
Query: 315 VTFVDKAVCRNNGFFSYHMPNW--FGTTKYV-KPLVQKLCTHE--------QMMCSKTCY 363
++F+ F+ +P + GT + V V +L E Q + S
Sbjct: 972 ISFIPD--------FAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVG 1023
Query: 364 NSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTD 423
++ FLIDGS S G F+ + + + ++ ++A +QF+ D + EF
Sbjct: 1024 GKRDVVFLIDGSQSAG-PEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 1082
Query: 424 YSTKENVLAVIRNIRYMSGGTA-TGDAISFTVRNVF----GPIRESPNKNFLVIVTDGQS 478
+S+K+ V ++ +R G G+A+ + RN+F G E FLV+++ G+S
Sbjct: 1083 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKS 1142
Query: 479 YDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFT-REFTGLE 531
D+V PA G+ F++ A ++L ++ P+ + T RE LE
Sbjct: 1143 DDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLE 1195
Score = 82.4 bits (202), Expect = 1e-15
Identities = 64/216 (29%), Positives = 102/216 (47%), Gaps = 22/216 (10%)
Query: 345 PLVQKLC--------THEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKT 396
PLV C TH Q + +S +I FLIDGS++ G NF ++L+F+ N+ +
Sbjct: 8 PLVAVFCLFLSGFPTTHAQQQ--QAAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEK 65
Query: 397 FEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTAT-GDAISFTVR 455
I ++ VQF+ + RT FS YSTK VL ++ + + G A G A+ F V
Sbjct: 66 LPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVE 125
Query: 456 NVF----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKD 511
N F G E LV+++ G S D+++ A A + F +G A +L+
Sbjct: 126 NHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQH 185
Query: 512 MASKPKESHAFFT----REFTGLEPIVSDVIRGICR 543
+A+ + + FT R F L+ + I G+ +
Sbjct: 186 IAT---DDNLVFTVPEFRSFGDLQEKLLPYIVGVAQ 218
>gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo
sapiens]
Length = 1036
Score = 138 bits (347), Expect = 1e-32
Identities = 111/387 (28%), Positives = 181/387 (46%), Gaps = 25/387 (6%)
Query: 163 KADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNF 222
K DI FL+DGS +G FN ++F+ KV L IG + V + Q ++ + EFY
Sbjct: 36 KRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTH 95
Query: 223 TSAKDVLFAIKEVGFRGGNS-NTGKALKHTAQKFFTVDAGVR--KGIPKVVVVFIDGWPS 279
+ ++V+ A++++ G++ TG AL FT AG R +GIPK++V+ G
Sbjct: 96 PTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 155
Query: 280 DDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGT 339
D+I + + + F + EL +++ F V +P F
Sbjct: 156 DEISQPAQELKRSSIMAFAIGNKGADQAEL---EEIAFDSSLV---------FIPAEFRA 203
Query: 340 TKYVKPLVQKLCTHEQMMCSKTCY-NSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFE 398
L L + + + N +I FL+DGS++VG +NF + +FV N+ + +
Sbjct: 204 APLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD 263
Query: 399 ISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSG-GTATGDAISFTVRNV 457
I + ++ VQF+ TEFS Y TK ++L +R ++ G G TG A+S+ N
Sbjct: 264 IGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANH 323
Query: 458 F-----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDM 512
F IRE L+++T GQS D A A AGI F VG + A +L+ +
Sbjct: 324 FTEAGGSRIREHV-PQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQI 382
Query: 513 ASKPKESHAFFTREFTGLEPIVSDVIR 539
A P S + +F+ L + +I+
Sbjct: 383 AFNP--SLVYLMDDFSSLPALPQQLIQ 407
Score = 127 bits (318), Expect = 3e-29
Identities = 101/383 (26%), Positives = 180/383 (46%), Gaps = 30/383 (7%)
Query: 147 KRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGL 206
+ L TPE + K DI FL+DGS N+G+ F ++FV + L IG + VGL
Sbjct: 218 RTLSGTPEVHSN----KRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGL 273
Query: 207 VQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNS-NTGKALKHTAQKFFTVDAG--VR 263
VQ S+ P EF L + + D+L ++++ +GG+ NTG AL + FT G +R
Sbjct: 274 VQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIR 333
Query: 264 KGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVC 323
+ +P+++++ G D +A G+ F V ++ EL + + F
Sbjct: 334 EHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAEL---EQIAF------ 384
Query: 324 RNNGFFSYHMPNWFGTTKYVKPLVQKLCTH-----EQMMCSKTCYNSVNIAFLIDGSSSV 378
N Y M ++ + L+Q L T+ E++ ++ + +I FL DGS+++
Sbjct: 385 --NPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQP-ESKRDILFLFDGSANL 441
Query: 379 GDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIR 438
F ++ +F+ I + G +IA Q++ D + E F ++ +K +L +++ ++
Sbjct: 442 -VGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMK 500
Query: 439 YMSGGTAT-GDAISFTVRNVF----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAG 493
+G G A+ + R +F G E FLV++ G+S D V GPA+ +G
Sbjct: 501 IKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSG 560
Query: 494 ITIFSVGVAWAPLDDLKDMASKP 516
+ F A +L+ + P
Sbjct: 561 VVPFIFQAKNADPAELEQIVLSP 583
Score = 123 bits (308), Expect = 5e-28
Identities = 104/414 (25%), Positives = 187/414 (45%), Gaps = 34/414 (8%)
Query: 138 VSTAHPPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGI 197
+ HP LK + D+ FL+DGS + + F L K FV +V L +
Sbjct: 595 IGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDV 653
Query: 198 GTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGG-NSNTGKALKHTAQKFF 256
G + V +VQ S+ + EFYL ++ + +DV+ A++++ GG NTG AL+ +
Sbjct: 654 GQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNIL 713
Query: 257 TVDAGVR--KGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQD 314
AG R +G+P++++V DD+ +V + G + + ++ +Q
Sbjct: 714 VSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGN---ADITEMQT 770
Query: 315 VTFVDKAVCRNNGFFSYHMPNW--FGTTKYV-KPLVQKLCTHE--------QMMCSKTCY 363
++F+ F+ +P + GT + V V +L E Q + S
Sbjct: 771 ISFIPD--------FAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVG 822
Query: 364 NSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTD 423
++ FLIDGS S G F+ + + + ++ ++A +QF+ D + EF
Sbjct: 823 GKRDVVFLIDGSQSAG-PEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 881
Query: 424 YSTKENVLAVIRNIRYMSGGTA-TGDAISFTVRNVF----GPIRESPNKNFLVIVTDGQS 478
+S+K+ V ++ +R G G+A+ + RN+F G E FLV+++ G+S
Sbjct: 882 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKS 941
Query: 479 YDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFT-REFTGLE 531
D+V PA G+ F++ A ++L ++ P+ + T RE LE
Sbjct: 942 DDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLE 994
Score = 83.6 bits (205), Expect = 4e-16
Identities = 53/182 (29%), Positives = 88/182 (48%), Gaps = 13/182 (7%)
Query: 345 PLVQKLC--------THEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKT 396
PLV C TH Q + N +I FL+DGSS++G +NF + +F++ + +
Sbjct: 8 PLVAVFCLFLSGFPTTHAQQQQAVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQR 67
Query: 397 FEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTA-TGDAISFTVR 455
EI ++A Q+ R EF F + TK V+ +R ++ + G TG A+ F
Sbjct: 68 LEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRN 127
Query: 456 NVF----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKD 511
N+F G LV++T G+S D++ PA + I F++G A +L++
Sbjct: 128 NLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEE 187
Query: 512 MA 513
+A
Sbjct: 188 IA 189
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor
[Homo sapiens]
Length = 3063
Score = 132 bits (332), Expect = 8e-31
Identities = 71/209 (33%), Positives = 116/209 (55%), Gaps = 10/209 (4%)
Query: 339 TTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFE 398
T KP+ +K E CS + + ++ FL+DGS SVG +NF+ +L+F++ + F+
Sbjct: 114 TGSSTKPVEKKPGKTEIQKCSVSAWT--DLVFLVDGSWSVGRNNFKYILDFIAALVSAFD 171
Query: 399 ISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVF 458
I + ++ VQ++ D RTEF+ Y ++ +LA I+ I Y G T TGDAI + V+N F
Sbjct: 172 IGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTF 231
Query: 459 GPIRESPN-----KNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMA 513
ES +I+TDG+S D+V+ PA + G+ +FS+G+ A +LK +A
Sbjct: 232 ---TESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIA 288
Query: 514 SKPKESHAFFTREFTGLEPIVSDVIRGIC 542
S P +H F F + I +++I +C
Sbjct: 289 STPSLNHVFNVANFDAIVDIQNEIISQVC 317
Score = 117 bits (293), Expect = 3e-26
Identities = 66/180 (36%), Positives = 103/180 (57%), Gaps = 5/180 (2%)
Query: 367 NIAFLIDGSSSVGDSNFRLMLEFVSNIAKTF-EISDIGAKIAAVQFTYDQRTEFSFTDYS 425
+I FL D S S+GD NF +++F+ N F EIS G +++ VQ++ + ++EF Y+
Sbjct: 2323 DIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYN 2382
Query: 426 TKENVLAVIRNIRYMSGGTATGDAISFTVRNVF---GPIRESPNKNFLVIVTDGQSYDDV 482
K L ++NIRY G T TG A++F V +R++ K LV+VTDG+S D+V
Sbjct: 2383 DKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPK-VLVVVTDGRSQDEV 2441
Query: 483 QGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGIC 542
+ A +G ++F VGVA ++L ++ASKP E H F +F E I ++I +C
Sbjct: 2442 KKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVC 2501
Score = 115 bits (287), Expect = 1e-25
Identities = 61/190 (32%), Positives = 106/190 (55%), Gaps = 2/190 (1%)
Query: 355 QMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYD 414
Q+ CS+ +I FL+DGS S+G +NF + F+ + K+FEIS +I+ VQ++ D
Sbjct: 428 QVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRD 487
Query: 415 QRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNK--NFLVI 472
TEF+ ++ E+++ I Y G T TG A+++ +F P + S + +++
Sbjct: 488 PHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMIL 547
Query: 473 VTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEP 532
+TDG+S D + PA ++ + IF+VGV A +L+ +AS P E+H F +F +
Sbjct: 548 ITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQR 607
Query: 533 IVSDVIRGIC 542
I ++ + IC
Sbjct: 608 ISFELTQSIC 617
Score = 113 bits (283), Expect = 4e-25
Identities = 61/179 (34%), Positives = 102/179 (56%), Gaps = 4/179 (2%)
Query: 367 NIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYST 426
+I L+DGS S+G +NFR + F+S I + F+I +IA Q++ D RTE+ +
Sbjct: 1199 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRD 1258
Query: 427 KENVLAVIRNIRYMSGGTATGDAISFTVRNVF---GPIRESPNKNFLVIVTDGQSYDDVQ 483
K+++L + N+ Y G T TG A++F + F +R K V++TDG+S DDV+
Sbjct: 1259 KKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARK-IGVLITDGKSQDDVE 1317
Query: 484 GPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGIC 542
P+ D G+ +F++G+ A +LK +A+ P ++HA+ +F L IV D+ +C
Sbjct: 1318 APSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLC 1376
Score = 105 bits (263), Expect = 8e-23
Identities = 56/149 (37%), Positives = 79/149 (53%)
Query: 161 DCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLK 220
D KADI FL+DGS++IG F + F+ + I + LVQ S P EF LK
Sbjct: 436 DIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLK 495
Query: 221 NFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSD 280
FT +D++ AI +RGG++NTGKA+ + +K F G R +PKV+++ DG SD
Sbjct: 496 KFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSD 555
Query: 281 DIEEAGIVAREFGVNVFIVSVAKPIPEEL 309
+ I R V +F V V + EL
Sbjct: 556 AFRDPAIKLRNSDVEIFAVGVKDAVRSEL 584
Score = 105 bits (262), Expect = 1e-22
Identities = 63/171 (36%), Positives = 90/171 (52%), Gaps = 1/171 (0%)
Query: 143 PPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFV-GKVALMLGIGTEG 201
PPT P + K KADI FL D S++IG FN F+ V I G
Sbjct: 2301 PPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAG 2360
Query: 202 PHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAG 261
V VQ S+ K EF L + L A++ + +RGGN+ TGKAL +K T ++G
Sbjct: 2361 IQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESG 2420
Query: 262 VRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMV 312
+RK +PKV+VV DG D++++A +V ++ G +VF+V VA EL +
Sbjct: 2421 MRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANI 2471
Score = 102 bits (254), Expect = 9e-22
Identities = 55/169 (32%), Positives = 87/169 (51%), Gaps = 7/169 (4%)
Query: 151 KTPEKKTGNKDCK-------ADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPH 203
K EKK G + + D+ FL+DGS+++G+ F +F+ + IG E
Sbjct: 119 KPVEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTR 178
Query: 204 VGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR 263
VG+VQ S + EF L + ++L AIK++ ++GGN+ TG A+ + + FT AG R
Sbjct: 179 VGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGAR 238
Query: 264 KGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMV 312
G PKV ++ DG D++E R GV VF + + +EL +
Sbjct: 239 VGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQI 287
Score = 89.7 bits (221), Expect = 6e-18
Identities = 47/150 (31%), Positives = 79/150 (52%)
Query: 163 KADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNF 222
+ADI L+DGS++IG+ F ++F+ ++ + IG + + L Q S P+ E+ L
Sbjct: 1197 EADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAH 1256
Query: 223 TSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDI 282
K +L A+ + ++GGN+ TG AL Q+ F AG+R K+ V+ DG DD+
Sbjct: 1257 RDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDV 1316
Query: 283 EEAGIVAREFGVNVFIVSVAKPIPEELGMV 312
E ++ GV +F + + EL M+
Sbjct: 1317 EAPSKKLKDEGVELFAIGIKNADEVELKMI 1346
>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
sapiens]
Length = 2570
Score = 129 bits (325), Expect = 5e-30
Identities = 106/379 (27%), Positives = 168/379 (44%), Gaps = 12/379 (3%)
Query: 163 KADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNF 222
K D+ FLIDGS + G F + + ++ L +G + V ++Q S+ PK+EF L
Sbjct: 624 KRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAH 682
Query: 223 TSAKDVLFAIKEVGFRGGNS-NTGKALKHTAQKFFTVDAGVR--KGIPKVVVVFIDGWPS 279
+S +V A++ + +GG N G AL++ ++ F G R +G+P+ +V+ G
Sbjct: 683 SSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSD 742
Query: 280 DDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGT 339
D++++ + ++FGV F ++ EEL + +V S
Sbjct: 743 DEVDDPAVELKQFGVAPFTIA-RNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPI 801
Query: 340 TKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEI 399
T +QKL + ++ +I FLID S V F + +FVS I + I
Sbjct: 802 TTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNI 861
Query: 400 SDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTA-TGDAISFTVRNVF 458
++ VQF+ D EF Y ++ VL IR +R G TG A+ F RN+F
Sbjct: 862 GPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLF 921
Query: 459 ----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMAS 514
G E LV+V G+S DDV A +GI VG +L+ + +
Sbjct: 922 VKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITN 981
Query: 515 KPKESHAFFTREFTGLEPI 533
P+ F REF L I
Sbjct: 982 DPR--LVFTVREFRELPNI 998
Score = 123 bits (308), Expect = 5e-28
Identities = 104/414 (25%), Positives = 187/414 (45%), Gaps = 34/414 (8%)
Query: 138 VSTAHPPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGI 197
+ HP LK + D+ FL+DGS + + F L K FV +V L +
Sbjct: 395 IGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDV 453
Query: 198 GTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGG-NSNTGKALKHTAQKFF 256
G + V +VQ S+ + EFYL ++ + +DV+ A++++ GG NTG AL+ +
Sbjct: 454 GQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNIL 513
Query: 257 TVDAGVR--KGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQD 314
AG R +G+P++++V DD+ +V + G + + ++ +Q
Sbjct: 514 VSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGN---ADITEMQT 570
Query: 315 VTFVDKAVCRNNGFFSYHMPNW--FGTTKYV-KPLVQKLCTHE--------QMMCSKTCY 363
++F+ F+ +P + GT + V V +L E Q + S
Sbjct: 571 ISFIPD--------FAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVG 622
Query: 364 NSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTD 423
++ FLIDGS S G F+ + + + ++ ++A +QF+ D + EF
Sbjct: 623 GKRDVVFLIDGSQSAG-PEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 681
Query: 424 YSTKENVLAVIRNIRYMSGGTA-TGDAISFTVRNVF----GPIRESPNKNFLVIVTDGQS 478
+S+K+ V ++ +R G G+A+ + RN+F G E FLV+++ G+S
Sbjct: 682 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKS 741
Query: 479 YDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFT-REFTGLE 531
D+V PA G+ F++ A ++L ++ P+ + T RE LE
Sbjct: 742 DDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLE 794
Score = 108 bits (270), Expect = 1e-23
Identities = 90/362 (24%), Positives = 165/362 (45%), Gaps = 22/362 (6%)
Query: 163 KADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNF 222
K DI FL+DGS +G FN ++F+ KV L IG + V + Q ++ + EFY
Sbjct: 36 KRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTH 95
Query: 223 TSAKDVLFAIKEVGFRGGNS-NTGKALKHTAQKFFTVDAGVR--KGIPKVVVVFIDGWPS 279
+ ++V+ A++++ G++ TG AL FT AG R +GIPK++V+ G
Sbjct: 96 PTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 155
Query: 280 DDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGT 339
D+I + + + F + EL +++ F V +P F
Sbjct: 156 DEISQPAQELKRSSIMAFAIGNKGADQAEL---EEIAFDSSLV---------FIPAEFRA 203
Query: 340 TKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEI 399
++ ++ L + + + +I FL DGS+++ F ++ +F+ I +
Sbjct: 204 AP-LQGMLPGLLAPLRTLSGTPEESKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNV 261
Query: 400 SDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTAT-GDAISFTVRNVF 458
G +IA Q++ D + E F ++ +K +L +++ ++ +G G A+ + R +F
Sbjct: 262 KPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIF 321
Query: 459 ----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMAS 514
G E FLV++ G+S D V GPA+ +G+ F A +L+ +
Sbjct: 322 VKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVL 381
Query: 515 KP 516
P
Sbjct: 382 SP 383
Score = 95.5 bits (236), Expect = 1e-19
Identities = 106/420 (25%), Positives = 177/420 (42%), Gaps = 53/420 (12%)
Query: 137 AVSTAHPPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLG 196
A + A P PEKK KADI FL+DGS N + F FV ++ +
Sbjct: 1010 AATPAPPGVDTPPPSRPEKK------KADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVY 1063
Query: 197 IGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGG-NSNTGKALKHTAQKF 255
+ VGLVQ + P EF+LK+F++ + ++ AI +V ++GG ++NT L+H
Sbjct: 1064 EDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNH 1123
Query: 256 FTVDAGVR--KGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQ 313
F +AG R + +P++ V G +D ++ + + GV VF V V EE+G +
Sbjct: 1124 FVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKI- 1182
Query: 314 DVTFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKL--CTHEQMM-----CSKTCYNSV 366
+N ++ + N ++ + +++ L HE + +K C V
Sbjct: 1183 ----------ASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDV 1232
Query: 367 NIAFLIDGSSS----VGDSNFRLMLEFVSN-IAKTFEISDIGAKIAAVQFTYDQRT---- 417
+ F DGS V F ++ + N I++ +S G + V+ + T
Sbjct: 1233 ILGF--DGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGP 1290
Query: 418 --EFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIV-- 473
F F +Y + +L RN+R T D T++ R+S + V++
Sbjct: 1291 VEAFDFDEY--QPEMLEKFRNMRSQHPYVLTED----TLKVYLNKFRQSSPDSVKVVIHF 1344
Query: 474 TDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPI 533
TDG G A H A + GV L L+ + + + H F R F P+
Sbjct: 1345 TDG-----ADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPL 1399
Score = 83.6 bits (205), Expect = 4e-16
Identities = 53/182 (29%), Positives = 88/182 (48%), Gaps = 13/182 (7%)
Query: 345 PLVQKLC--------THEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKT 396
PLV C TH Q + N +I FL+DGSS++G +NF + +F++ + +
Sbjct: 8 PLVAVFCLFLSGFPTTHAQQQQAVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQR 67
Query: 397 FEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTA-TGDAISFTVR 455
EI ++A Q+ R EF F + TK V+ +R ++ + G TG A+ F
Sbjct: 68 LEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRN 127
Query: 456 NVF----GPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKD 511
N+F G LV++T G+S D++ PA + I F++G A +L++
Sbjct: 128 NLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEE 187
Query: 512 MA 513
+A
Sbjct: 188 IA 189
Score = 47.4 bits (111), Expect = 3e-05
Identities = 33/125 (26%), Positives = 61/125 (48%), Gaps = 20/125 (16%)
Query: 366 VNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIG------AKIAAVQFTYDQ---- 415
+++AF++D + + F M ++++ + + ++S A++A VQ +
Sbjct: 2011 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2070
Query: 416 ------RTEFSFTDYSTKENVLAVI-RNIRYMSGGTATGDAISFTVRNVFGPIRESPNKN 468
+ EFS TDY +KE ++ + R + + G A G AI +T+ NVF +PN
Sbjct: 2071 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVF---ESAPNPR 2127
Query: 469 FLVIV 473
L IV
Sbjct: 2128 DLKIV 2132
Score = 43.5 bits (101), Expect = 5e-04
Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Query: 368 IAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDI----GAKIAAVQFTYDQRTEFSFTD 423
+AF +D S V F M + V +I I++ GA++A V + + TE F D
Sbjct: 1796 LAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFAD 1855
Query: 424 YSTKENVLAVIRNIR--YMSGGTATGDAISFTVRNVFGPIR 462
K +L I+N++ S + A+SF RN F +R
Sbjct: 1856 SKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVR 1896
Score = 33.5 bits (75), Expect = 0.52
Identities = 32/150 (21%), Positives = 62/150 (41%), Gaps = 20/150 (13%)
Query: 154 EKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTE---GPHVGLVQAS 210
+++ D D+AF++D + +FN K ++ + L + + H V
Sbjct: 2001 DRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVV 2060
Query: 211 EHP-------------KIEFYLKNFTSAKDVL-FAIKEVGFRGGNSNTGKALKHTAQKFF 256
+H K+EF L ++ S + ++ F + + G G A+++T + F
Sbjct: 2061 QHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVF 2120
Query: 257 TVDAGVRKGIPKVVVVFIDG-WPSDDIEEA 285
R K+VV+ + G P +EEA
Sbjct: 2121 ESAPNPRD--LKIVVLMLTGEVPEQQLEEA 2148
>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
Length = 1626
Score = 120 bits (301), Expect = 3e-27
Identities = 68/201 (33%), Positives = 109/201 (54%), Gaps = 8/201 (3%)
Query: 351 CTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQ 410
C ++ C Y+ V FL+D SSSVG +F + ++V+N+ TFE+ ++ V+
Sbjct: 25 CQAQRAGCKSVHYDLV---FLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVR 81
Query: 411 FTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPI-----RESP 465
++ T F + ++E V A R + Y G T TGDA+ + F P R+
Sbjct: 82 YSDRPTTAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRA 141
Query: 466 NKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTR 525
K +++TDG+S D V AAAAH AGI IF+VGV A ++L+++AS+PK +H F
Sbjct: 142 YKQVAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVS 201
Query: 526 EFTGLEPIVSDVIRGICRDFL 546
+F ++ I + R +C + L
Sbjct: 202 DFNAIDKIRGKLRRRLCENVL 222
Score = 85.9 bits (211), Expect = 9e-17
Identities = 54/207 (26%), Positives = 99/207 (47%), Gaps = 14/207 (6%)
Query: 155 KKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPK 214
++ G K D+ FL+D S ++G+ F + +V + +G + VG+V+ S+ P
Sbjct: 28 QRAGCKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPT 87
Query: 215 IEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR---KGIPKVVV 271
F L F S ++V A + + + GGN+NTG AL++ + F+ AG R + +V +
Sbjct: 88 TAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAI 147
Query: 272 VFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSY 331
+ DG D + +A A G+ +F V V + + EEL ++ +
Sbjct: 148 LLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEEL---------EEIASEPKSAHVF 198
Query: 332 HMPNWFGTTKYVKPLVQKLCTHEQMMC 358
H+ ++ K L ++LC E ++C
Sbjct: 199 HVSDFNAIDKIRGKLRRRLC--ENVLC 223
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 119 bits (297), Expect = 9e-27
Identities = 57/178 (32%), Positives = 102/178 (57%), Gaps = 2/178 (1%)
Query: 367 NIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYST 426
+I L+DGS S+G NFRL+ F+ N+ F++ +I Q++ D R E+ +ST
Sbjct: 158 DIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWHLNAFST 217
Query: 427 KENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPN--KNFLVIVTDGQSYDDVQG 484
K+ V+ +RN+ Y G T TG A+++ N F P S +++TDG+S DD+
Sbjct: 218 KDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILITDGKSQDDIIP 277
Query: 485 PAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGIC 542
P+ ++G+ +F++GV A +++L+++AS+P +H + EF + +V + R +C
Sbjct: 278 PSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNVAEFDLMHTVVESLTRTLC 335
Score = 118 bits (295), Expect = 2e-26
Identities = 67/181 (37%), Positives = 99/181 (54%), Gaps = 7/181 (3%)
Query: 367 NIAFLIDGSSSVGDSNFRLMLEFV-SNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYS 425
++ F++DGS S+GD NF ++ F+ S + +I G ++A VQFT D RTEF Y
Sbjct: 1032 DLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTEFKLNAYK 1091
Query: 426 TKENVLAVIRNIRYMSGGTATGDAISFTVRNVF----GPIRESPNKNFLVIVTDGQSYDD 481
TKE +L I++I Y G T TG AI + +F G R P +V++TDG+S DD
Sbjct: 1092 TKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRRGIP--KVIVVITDGRSQDD 1149
Query: 482 VQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGI 541
V + G +IF++GVA A +L + SKP H FF +F + I ++I +
Sbjct: 1150 VNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKKIEDELITFV 1209
Query: 542 C 542
C
Sbjct: 1210 C 1210
Score = 116 bits (290), Expect = 6e-26
Identities = 63/168 (37%), Positives = 96/168 (57%), Gaps = 7/168 (4%)
Query: 143 PPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFV-GKVALMLGIGTEG 201
PPT P K K KAD+ F++DGS++IG FN +F+ V + IGT+G
Sbjct: 1016 PPT------IPPAKEVCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDG 1069
Query: 202 PHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAG 261
V +VQ ++ P+ EF L + + + +L AIK + ++GGN+ TGKA+K+ FT ++G
Sbjct: 1070 TQVAMVQFTDDPRTEFKLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESG 1129
Query: 262 VRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEEL 309
R+GIPKV+VV DG DD+ + + G ++F + VA EL
Sbjct: 1130 TRRGIPKVIVVITDGRSQDDVNKISREMQLDGYSIFAIGVADADYSEL 1177
Score = 99.8 bits (247), Expect = 6e-21
Identities = 51/146 (34%), Positives = 84/146 (57%)
Query: 164 ADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFT 223
ADI L+DGS++IG+ F L ++F+ + +G+E +GL Q S P+IE++L F+
Sbjct: 157 ADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWHLNAFS 216
Query: 224 SAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDIE 283
+ +V+ A++ + ++GGN+ TG AL + + F +AG R G+ K+ ++ DG DDI
Sbjct: 217 TKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILITDGKSQDDII 276
Query: 284 EAGIVAREFGVNVFIVSVAKPIPEEL 309
RE GV +F + V EL
Sbjct: 277 PPSRNLRESGVELFAIGVKNADVNEL 302
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
sapiens]
Length = 1899
Score = 117 bits (293), Expect = 3e-26
Identities = 66/180 (36%), Positives = 103/180 (57%), Gaps = 5/180 (2%)
Query: 367 NIAFLIDGSSSVGDSNFRLMLEFVSNIAKTF-EISDIGAKIAAVQFTYDQRTEFSFTDYS 425
+I FL D S S+GD NF +++F+ N F EIS G +++ VQ++ + ++EF Y+
Sbjct: 1159 DIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYN 1218
Query: 426 TKENVLAVIRNIRYMSGGTATGDAISFTVRNVF---GPIRESPNKNFLVIVTDGQSYDDV 482
K L ++NIRY G T TG A++F V +R++ K LV+VTDG+S D+V
Sbjct: 1219 DKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPK-VLVVVTDGRSQDEV 1277
Query: 483 QGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGIC 542
+ A +G ++F VGVA ++L ++ASKP E H F +F E I ++I +C
Sbjct: 1278 KKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVC 1337
Score = 113 bits (283), Expect = 4e-25
Identities = 61/179 (34%), Positives = 102/179 (56%), Gaps = 4/179 (2%)
Query: 367 NIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYST 426
+I L+DGS S+G +NFR + F+S I + F+I +IA Q++ D RTE+ +
Sbjct: 35 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRD 94
Query: 427 KENVLAVIRNIRYMSGGTATGDAISFTVRNVF---GPIRESPNKNFLVIVTDGQSYDDVQ 483
K+++L + N+ Y G T TG A++F + F +R K V++TDG+S DDV+
Sbjct: 95 KKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARK-IGVLITDGKSQDDVE 153
Query: 484 GPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGIC 542
P+ D G+ +F++G+ A +LK +A+ P ++HA+ +F L IV D+ +C
Sbjct: 154 APSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLC 212
Score = 105 bits (262), Expect = 1e-22
Identities = 63/171 (36%), Positives = 90/171 (52%), Gaps = 1/171 (0%)
Query: 143 PPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFV-GKVALMLGIGTEG 201
PPT P + K KADI FL D S++IG FN F+ V I G
Sbjct: 1137 PPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAG 1196
Query: 202 PHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAG 261
V VQ S+ K EF L + L A++ + +RGGN+ TGKAL +K T ++G
Sbjct: 1197 IQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESG 1256
Query: 262 VRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMV 312
+RK +PKV+VV DG D++++A +V ++ G +VF+V VA EL +
Sbjct: 1257 MRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANI 1307
Score = 89.7 bits (221), Expect = 6e-18
Identities = 47/150 (31%), Positives = 79/150 (52%)
Query: 163 KADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNF 222
+ADI L+DGS++IG+ F ++F+ ++ + IG + + L Q S P+ E+ L
Sbjct: 33 EADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAH 92
Query: 223 TSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDI 282
K +L A+ + ++GGN+ TG AL Q+ F AG+R K+ V+ DG DD+
Sbjct: 93 RDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDV 152
Query: 283 EEAGIVAREFGVNVFIVSVAKPIPEELGMV 312
E ++ GV +F + + EL M+
Sbjct: 153 EAPSKKLKDEGVELFAIGIKNADEVELKMI 182
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 108 bits (271), Expect = 1e-23
Identities = 58/197 (29%), Positives = 112/197 (56%), Gaps = 7/197 (3%)
Query: 358 CSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRT 417
C K +++ F+IDGS S+G+ NF ++ +FV+ I + IS A++ +Q++ T
Sbjct: 646 CKKCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHT 705
Query: 418 EFSFTDYSTKENVLAVIRNIRYMSGGTATGDAI------SFTVRNVFGPIRESPNKNFLV 471
EF+ ++++ +++ + +++YM G+ TG A+ SFT P+ + +
Sbjct: 706 EFTLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPL-STRVPRAAI 764
Query: 472 IVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLE 531
+ TDG++ DDV A+ A GIT+++VGV A ++L+++AS+P H F+ +F+ ++
Sbjct: 765 VFTDGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLFYAEDFSTMD 824
Query: 532 PIVSDVIRGICRDFLES 548
I + +GIC +S
Sbjct: 825 EISEKLKKGICEALEDS 841
Score = 102 bits (255), Expect = 7e-22
Identities = 61/199 (30%), Positives = 102/199 (51%), Gaps = 9/199 (4%)
Query: 352 THEQM-MCSKTCYNS-VNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAV 409
TH Q + +C N ++ F+ID S SV ++ + EF+ +I + +I ++ +
Sbjct: 40 THPQTALLESSCENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLL 99
Query: 410 QFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFG------PIRE 463
Q+ + EFS + K V ++ +R++S GT TG AI + + F P+RE
Sbjct: 100 QYGSTVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRE 159
Query: 464 SPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFF 523
+ + ++IVTDG+ D V AA A D GI IF++GV + LK + S+P E H F
Sbjct: 160 NVPR-VIMIVTDGRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFL 218
Query: 524 TREFTGLEPIVSDVIRGIC 542
F+ +E + S + +C
Sbjct: 219 VANFSQIETLTSVFQKKLC 237
Score = 102 bits (254), Expect = 9e-22
Identities = 62/167 (37%), Positives = 87/167 (52%), Gaps = 10/167 (5%)
Query: 146 GKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVG 205
G+R KK E D+ F+IDGS ++G+ F + K FV + L I + VG
Sbjct: 643 GRRCKKCTEGPI-------DLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVG 695
Query: 206 LVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR-- 263
L+Q S EF L+NF SAKD+ A+ + + G S TG ALKH ++ FT G R
Sbjct: 696 LLQYSTQVHTEFTLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPL 755
Query: 264 -KGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEEL 309
+P+ +VF DG DD+ E A+ G+ ++ V V K I EEL
Sbjct: 756 STRVPRAAIVFTDGRAQDDVSEWASKAKANGITMYAVGVGKAIEEEL 802
Score = 78.6 bits (192), Expect = 1e-14
Identities = 59/236 (25%), Positives = 100/236 (42%), Gaps = 17/236 (7%)
Query: 146 GKRLKKTPEKKTGNKDC---KADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGP 202
G+ + P+ C +AD+ F+ID S ++ + K F+ + L IG +
Sbjct: 35 GRHARTHPQTALLESSCENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVT 94
Query: 203 HVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAG- 261
VGL+Q K EF LK F +V A+K + + TG A+++ F+ G
Sbjct: 95 RVGLLQYGSTVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGA 154
Query: 262 --VRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVD 319
+R+ +P+V+++ DG P D + E AR+ G+ +F + V + L + D
Sbjct: 155 RPLRENVPRVIMIVTDGRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHED 214
Query: 320 KAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGS 375
+ + N+ +KLCT MCS +N + I GS
Sbjct: 215 HV---------FLVANFSQIETLTSVFQKKLCTAH--MCSTLEHNCAHFCINIPGS 259
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 108 bits (271), Expect = 1e-23
Identities = 58/197 (29%), Positives = 112/197 (56%), Gaps = 7/197 (3%)
Query: 358 CSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRT 417
C K +++ F+IDGS S+G+ NF ++ +FV+ I + IS A++ +Q++ T
Sbjct: 646 CKKCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHT 705
Query: 418 EFSFTDYSTKENVLAVIRNIRYMSGGTATGDAI------SFTVRNVFGPIRESPNKNFLV 471
EF+ ++++ +++ + +++YM G+ TG A+ SFT P+ + +
Sbjct: 706 EFTLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPL-STRVPRAAI 764
Query: 472 IVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLE 531
+ TDG++ DDV A+ A GIT+++VGV A ++L+++AS+P H F+ +F+ ++
Sbjct: 765 VFTDGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLFYAEDFSTMD 824
Query: 532 PIVSDVIRGICRDFLES 548
I + +GIC +S
Sbjct: 825 EISEKLKKGICEALEDS 841
Score = 102 bits (255), Expect = 7e-22
Identities = 61/199 (30%), Positives = 102/199 (51%), Gaps = 9/199 (4%)
Query: 352 THEQM-MCSKTCYNS-VNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAV 409
TH Q + +C N ++ F+ID S SV ++ + EF+ +I + +I ++ +
Sbjct: 40 THPQTALLESSCENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLL 99
Query: 410 QFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFG------PIRE 463
Q+ + EFS + K V ++ +R++S GT TG AI + + F P+RE
Sbjct: 100 QYGSTVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRE 159
Query: 464 SPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFF 523
+ + ++IVTDG+ D V AA A D GI IF++GV + LK + S+P E H F
Sbjct: 160 NVPR-VIMIVTDGRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFL 218
Query: 524 TREFTGLEPIVSDVIRGIC 542
F+ +E + S + +C
Sbjct: 219 VANFSQIETLTSVFQKKLC 237
Score = 102 bits (254), Expect = 9e-22
Identities = 62/167 (37%), Positives = 87/167 (52%), Gaps = 10/167 (5%)
Query: 146 GKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVG 205
G+R KK E D+ F+IDGS ++G+ F + K FV + L I + VG
Sbjct: 643 GRRCKKCTEGPI-------DLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVG 695
Query: 206 LVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR-- 263
L+Q S EF L+NF SAKD+ A+ + + G S TG ALKH ++ FT G R
Sbjct: 696 LLQYSTQVHTEFTLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPL 755
Query: 264 -KGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEEL 309
+P+ +VF DG DD+ E A+ G+ ++ V V K I EEL
Sbjct: 756 STRVPRAAIVFTDGRAQDDVSEWASKAKANGITMYAVGVGKAIEEEL 802
Score = 78.6 bits (192), Expect = 1e-14
Identities = 59/236 (25%), Positives = 100/236 (42%), Gaps = 17/236 (7%)
Query: 146 GKRLKKTPEKKTGNKDC---KADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGP 202
G+ + P+ C +AD+ F+ID S ++ + K F+ + L IG +
Sbjct: 35 GRHARTHPQTALLESSCENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVT 94
Query: 203 HVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAG- 261
VGL+Q K EF LK F +V A+K + + TG A+++ F+ G
Sbjct: 95 RVGLLQYGSTVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGA 154
Query: 262 --VRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVD 319
+R+ +P+V+++ DG P D + E AR+ G+ +F + V + L + D
Sbjct: 155 RPLRENVPRVIMIVTDGRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHED 214
Query: 320 KAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGS 375
+ + N+ +KLCT MCS +N + I GS
Sbjct: 215 HV---------FLVANFSQIETLTSVFQKKLCTAH--MCSTLEHNCAHFCINIPGS 259
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 105 bits (263), Expect = 8e-23
Identities = 65/192 (33%), Positives = 101/192 (52%), Gaps = 5/192 (2%)
Query: 354 EQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFE--ISDIGAKIAAVQF 411
E++ C++ + +I FL+DGSSS+G SNFR + F+ + F S G + A VQ+
Sbjct: 27 ERVTCTRLY--AADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQY 84
Query: 412 TYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPN-KNFL 470
+ D RTEF + +V+ IR + Y G T TG AI +VF P P
Sbjct: 85 SDDPRTEFGLDALGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQLARPGVPKVC 144
Query: 471 VIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGL 530
+++TDG+S D V A G+ +F+VG+ A ++LK +AS+P FF +F+ L
Sbjct: 145 ILITDGKSQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSIL 204
Query: 531 EPIVSDVIRGIC 542
++ V R +C
Sbjct: 205 RTLLPLVSRRVC 216
Score = 92.0 bits (227), Expect = 1e-18
Identities = 66/202 (32%), Positives = 99/202 (49%), Gaps = 14/202 (6%)
Query: 154 EKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLG--IGTEGPHVGLVQASE 211
E+ T + ADI FL+DGS +IG+ F ++F+ + L +G VQ S+
Sbjct: 27 ERVTCTRLYAADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSD 86
Query: 212 HPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVV 271
P+ EF L S DV+ AI+E+ ++GGN+ TG A+ H A F R G+PKV +
Sbjct: 87 DPRTEFGLDALGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQL-ARPGVPKVCI 145
Query: 272 VFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSY 331
+ DG D ++ A + GV +F V + PEEL V D FF +
Sbjct: 146 LITDGKSQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSD--------FFFF 197
Query: 332 HMPNWFGTTKYVKPLV-QKLCT 352
N F + + PLV +++CT
Sbjct: 198 --VNDFSILRTLLPLVSRRVCT 217
Score = 40.4 bits (93), Expect = 0.004
Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 4/149 (2%)
Query: 164 ADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLG-IGTEGPHVGLVQASEHPKIEFYLKNF 222
AD+ FL + + R + + ++ L LG +G + VGL+ S P F L
Sbjct: 1053 ADVVFLPHATQD-NAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSHRPSPLFPLNGS 1111
Query: 223 TSAKDVLFAIKEVGFRG-GNSNTGKALKHTAQKFFTVDA-GVRKGIPKVVVVFIDGWPSD 280
+L I+++ + +N G A+ + DA G R+ +P V+V+ +D
Sbjct: 1112 HDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAPDAPGRRQHVPGVMVLLVDEPLRG 1171
Query: 281 DIEEAGIVAREFGVNVFIVSVAKPIPEEL 309
DI A+ G+NV ++ +A PE+L
Sbjct: 1172 DIFSPIREAQASGLNVVMLGMAGADPEQL 1200
Score = 33.5 bits (75), Expect = 0.52
Identities = 29/127 (22%), Positives = 55/127 (43%), Gaps = 9/127 (7%)
Query: 430 VLAVIRNIRYMS-GGTATGDAISFTVRNVFGPIRESPNKN-----FLVIVTDGQSYDDVQ 483
+L IR++ YM G G A+ R + P ++P + +V++ D D+
Sbjct: 1117 ILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAP--DAPGRRQHVPGVMVLLVDEPLRGDIF 1174
Query: 484 GPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFF-TREFTGLEPIVSDVIRGIC 542
P A +G+ + +G+A A + L+ +A FF + L+ VS + +C
Sbjct: 1175 SPIREAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQAVSGLATALC 1234
Query: 543 RDFLESQ 549
+ +Q
Sbjct: 1235 QASFTTQ 1241
>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
Length = 957
Score = 104 bits (259), Expect = 2e-22
Identities = 56/179 (31%), Positives = 100/179 (55%), Gaps = 2/179 (1%)
Query: 367 NIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYST 426
++ F++DGS SVG NF ++ +++ NI K F+I ++ VQ++ E Y +
Sbjct: 37 DLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGSYDS 96
Query: 427 KENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIVTDGQSYDDVQGPA 486
E++ A + +I Y+ G T TG AI F + +F K V++TDG+S DDV+ A
Sbjct: 97 GEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSSRFLTK-IAVVLTDGKSQDDVKDAA 155
Query: 487 AAAHDAGITIFSVGVAWAPLD-DLKDMASKPKESHAFFTREFTGLEPIVSDVIRGICRD 544
AA D+ IT+F++GV D +L+ +A+KP ++ F+ ++ + I + + +C +
Sbjct: 156 QAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKIREVMKQKLCEE 214
Score = 87.8 bits (216), Expect = 2e-17
Identities = 52/211 (24%), Positives = 108/211 (51%), Gaps = 15/211 (7%)
Query: 149 LKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQ 208
L + E ++ + D+ F++DGS+++G F + K ++ + IG + VG+VQ
Sbjct: 21 LAEDGEVRSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQ 80
Query: 209 ASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPK 268
S++P +E L ++ S + + A++ + + GGN+ TGKA++ F A + + K
Sbjct: 81 YSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLF---AKSSRFLTK 137
Query: 269 VVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPE-ELGMVQDVTFVDKAVCRNNG 327
+ VV DG DD+++A AR+ + +F + V + EL + + + +
Sbjct: 138 IAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIAN---------KPSS 188
Query: 328 FFSYHMPNWFGTTKYVKPLVQKLCTHEQMMC 358
+ +++ ++ +K + + QKLC E+ +C
Sbjct: 189 TYVFYVEDYIAISKIREVMKQKLC--EESVC 217
>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
Length = 1284
Score = 104 bits (259), Expect = 2e-22
Identities = 60/180 (33%), Positives = 100/180 (55%), Gaps = 4/180 (2%)
Query: 367 NIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYST 426
++ FL+DGS S+G S+F+ + +F++++ FEI ++ Q++ D +TE+ ST
Sbjct: 179 DMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLST 238
Query: 427 KENVLAVIRNIRYMSGGTATGDAISFTVRNVFGP---IRESPNKNFLVIVTDGQSYDDVQ 483
KE VLA +R +RY G T TG A++ + P +R K +++VTDG+S DDV
Sbjct: 239 KEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAK-VVILVTDGKSQDDVH 297
Query: 484 GPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGICR 543
A D G+ +F+VGV A +L+ +AS P++ +F L + + R IC+
Sbjct: 298 TAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQ 357
Score = 96.7 bits (239), Expect = 5e-20
Identities = 54/149 (36%), Positives = 82/149 (55%)
Query: 164 ADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFT 223
AD+ FL+DGS++IG F K+F+ V IG + VGL Q S + E+ L + +
Sbjct: 178 ADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLS 237
Query: 224 SAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDIE 283
+ + VL A++ + ++GGN+ TG AL H + AG+R KVV++ DG DD+
Sbjct: 238 TKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDDVH 297
Query: 284 EAGIVAREFGVNVFIVSVAKPIPEELGMV 312
A V ++ GVNVF V V EL ++
Sbjct: 298 TAARVLKDLGVNVFAVGVKNADEAELRLL 326
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 103 bits (257), Expect = 4e-22
Identities = 87/353 (24%), Positives = 159/353 (45%), Gaps = 39/353 (11%)
Query: 165 DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTS 224
D+AF+++GS IG+ FN K F+ +V + +G + HV ++Q S +E+ S
Sbjct: 1498 DVAFVLEGSDKIGEADFNRSKEFMEEVIQRMDVGQDSIHVTVLQYSYMVTVEYPFSEAQS 1557
Query: 225 AKDVLFAIKEVGFRGGN-SNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDIE 283
D+L ++E+ ++GGN +NTG AL++ + F V G R+ P +V + SD+I+
Sbjct: 1558 KGDILQRVREIRYQGGNRTNTGLALRYLSDHSFLVSQGDREQAPNLVYMVTGNPASDEIK 1617
Query: 284 ----EAGIVAREFGVNVFIVSVAK-PIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFG 338
+ +V G N + + + P ++QD F
Sbjct: 1618 RLPGDIQVVPIGVGPNANVQELERIGWPNAPILIQD----------------------FE 1655
Query: 339 TTKYVKP--LVQKLCTHEQMMC-----SKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVS 391
T P ++Q+ C+ E + + C +++ L+DGSSS S F M F
Sbjct: 1656 TLPREAPDLVLQRCCSGEGLQIPTLSPAPDCSQPLDVILLLDGSSSFPASYFDEMKSFAK 1715
Query: 392 NIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAIS 451
I +++ +Q+ + + K ++L+++ ++ G + GDA+
Sbjct: 1716 AFISKANIGPRLTQVSVLQYGSITTIDVPWNVVPEKAHLLSLVDVMQREGGPSQIGDALG 1775
Query: 452 FTVRNVFGPI---RESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGV 501
F VR + + R +K +++VTD S D V A AA +T+F +G+
Sbjct: 1776 FAVRYLTSEMHGARPGASKAVVILVTD-VSVDSVDAAADAARSNRVTVFPIGI 1827
Score = 62.0 bits (149), Expect = 1e-09
Identities = 74/355 (20%), Positives = 150/355 (42%), Gaps = 50/355 (14%)
Query: 165 DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTS 224
D+ FL+DGS + + F + K FV + L I + V +V+ + LK+
Sbjct: 1277 DLVFLLDGSSRLSEAEFEVLKAFVVDMMERLRISQKWVRVAVVEYHDGSHAYIGLKDRKR 1336
Query: 225 AKDVLFAIKEVGFRGGN-SNTGKALKHTA-QKFFTVDAGVRKGIPKVVVVFIDGWPSDDI 282
++ +V + G ++T + LK+T Q F +D R ++ ++ +
Sbjct: 1337 PSELRRIASQVKYAGSQVASTSEVLKYTLFQIFSKID---RPEASRITLLLMAS------ 1387
Query: 283 EEAGIVAREFGVNVFIVSVAKPIPEELGM-----VQDVTFVDKAVCRNNGFFSYHMPNWF 337
+E ++R F V + K I +G+ ++ + ++K N F +
Sbjct: 1388 QEPQRMSRNFVRYVQGLKKKKVIVIPVGIGPHANLKQIRLIEKQAPENKAFVLSSVDE-- 1445
Query: 338 GTTKYVKPLVQKLC---------THEQMMCSKTC-------------YNSV--NIAFLID 373
+ +V LC T M T NS+ ++AF+++
Sbjct: 1446 -LEQQRDEIVSYLCDLAPEAPPPTLPPDMAQVTVGPGLLGVSTLGPKRNSMVLDVAFVLE 1504
Query: 374 GSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAV 433
GS +G+++F EF+ + + ++ + +Q++Y E+ F++ +K ++L
Sbjct: 1505 GSDKIGEADFNRSKEFMEEVIQRMDVGQDSIHVTVLQYSYMVTVEYPFSEAQSKGDILQR 1564
Query: 434 IRNIRYMSGG-TATGDAISFTVRNVF----GPIRESPNKNFLVIVTDGQSYDDVQ 483
+R IRY G T TG A+ + + F G ++P N + +VT + D+++
Sbjct: 1565 VREIRYQGGNRTNTGLALRYLSDHSFLVSQGDREQAP--NLVYMVTGNPASDEIK 1617
Score = 43.5 bits (101), Expect = 5e-04
Identities = 32/187 (17%), Positives = 73/187 (39%), Gaps = 6/187 (3%)
Query: 362 CYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSF 421
C +++ FL+DGSS + ++ F ++ FV ++ + IS ++A V++
Sbjct: 1272 CSRLLDLVFLLDGSSRLSEAEFEVLKAFVVDMMERLRISQKWVRVAVVEYHDGSHAYIGL 1331
Query: 422 TDYSTKENVLAVIRNIRYMSGGTA-TGDAISFTVRNVFGPIRESPNKNFLVIVTDGQSYD 480
D + + ++Y A T + + +T+ +F I +++ Q
Sbjct: 1332 KDRKRPSELRRIASQVKYAGSQVASTSEVLKYTLFQIFSKIDRPEASRITLLLMASQEPQ 1391
Query: 481 DVQGP----AAAAHDAGITIFSVGVA-WAPLDDLKDMASKPKESHAFFTREFTGLEPIVS 535
+ + + VG+ A L ++ + + E+ AF LE
Sbjct: 1392 RMSRNFVRYVQGLKKKKVIVIPVGIGPHANLKQIRLIEKQAPENKAFVLSSVDELEQQRD 1451
Query: 536 DVIRGIC 542
+++ +C
Sbjct: 1452 EIVSYLC 1458
Score = 43.1 bits (100), Expect = 7e-04
Identities = 35/143 (24%), Positives = 54/143 (37%), Gaps = 2/143 (1%)
Query: 161 DCKA--DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFY 218
DC D+ L+DGS + F+ K+F IG V ++Q I+
Sbjct: 1685 DCSQPLDVILLLDGSSSFPASYFDEMKSFAKAFISKANIGPRLTQVSVLQYGSITTIDVP 1744
Query: 219 LKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWP 278
+L + + GG S G AL + + G R G K VV+ +
Sbjct: 1745 WNVVPEKAHLLSLVDVMQREGGPSQIGDALGFAVRYLTSEMHGARPGASKAVVILVTDVS 1804
Query: 279 SDDIEEAGIVAREFGVNVFIVSV 301
D ++ A AR V VF + +
Sbjct: 1805 VDSVDAAADAARSNRVTVFPIGI 1827
>gi|13699834 matrilin 4 isoform 2 precursor [Homo sapiens]
Length = 540
Score = 103 bits (256), Expect = 5e-22
Identities = 60/190 (31%), Positives = 98/190 (51%), Gaps = 5/190 (2%)
Query: 358 CSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRT 417
C++ V++ L+DGS SV NF L+ FV+ I ++S G ++ VQF+ RT
Sbjct: 295 CNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRT 354
Query: 418 EFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLV-----I 472
EF Y T V + + YM GT TG A+ V + F + + + V +
Sbjct: 355 EFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLV 414
Query: 473 VTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEP 532
TDG+S DD+ AA A + GI +++VGV A +L+++AS+P E H + +F +
Sbjct: 415 FTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTH 474
Query: 533 IVSDVIRGIC 542
++ ++ IC
Sbjct: 475 LLENLRGSIC 484
Score = 89.4 bits (220), Expect = 8e-18
Identities = 54/169 (31%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 144 PTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPH 203
P G++L+ + ++ D+ L+DGS ++ + F L K FV ++ L + EG
Sbjct: 283 PEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTR 342
Query: 204 VGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR 263
VGLVQ S + EF L + +A +V A+ V + + TG AL+H + F+ G R
Sbjct: 343 VGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGAR 402
Query: 264 K---GIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEEL 309
+P+V +VF DG DDI A+E G+ ++ V V K + EL
Sbjct: 403 PRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAEL 451
Score = 81.6 bits (200), Expect = 2e-15
Identities = 53/187 (28%), Positives = 88/187 (47%), Gaps = 5/187 (2%)
Query: 346 LVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAK 405
L+Q T Q+ + +++ F+ID S SV F M +F+ + + + +
Sbjct: 13 LLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATR 72
Query: 406 IAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIR--- 462
+ +Q++ ++ F +S +E++ IR++ ++ GT TG AI + + F
Sbjct: 73 VGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGAR 132
Query: 463 --ESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESH 520
E VIVTDG+ D V AA A GI I++VGV A + L+ MAS P + H
Sbjct: 133 PPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEH 192
Query: 521 AFFTREF 527
F F
Sbjct: 193 VFLVESF 199
Score = 66.2 bits (160), Expect = 7e-11
Identities = 39/142 (27%), Positives = 71/142 (50%), Gaps = 3/142 (2%)
Query: 165 DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTS 224
D+ F+ID S ++ F + F+ + L +G VG++Q S + F L+ F+
Sbjct: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
Query: 225 AKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR---KGIPKVVVVFIDGWPSDD 281
+D+ AI+++ + TG A+++ F+V G R + +P+V V+ DG P D
Sbjct: 94 REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
Query: 282 IEEAGIVAREFGVNVFIVSVAK 303
+ E AR G+ ++ V V +
Sbjct: 154 VAEVAAQARARGIEIYAVGVQR 175
>gi|13699830 matrilin 4 isoform 1 precursor [Homo sapiens]
Length = 581
Score = 103 bits (256), Expect = 5e-22
Identities = 60/190 (31%), Positives = 98/190 (51%), Gaps = 5/190 (2%)
Query: 358 CSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRT 417
C++ V++ L+DGS SV NF L+ FV+ I ++S G ++ VQF+ RT
Sbjct: 336 CNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRT 395
Query: 418 EFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLV-----I 472
EF Y T V + + YM GT TG A+ V + F + + + V +
Sbjct: 396 EFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLV 455
Query: 473 VTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEP 532
TDG+S DD+ AA A + GI +++VGV A +L+++AS+P E H + +F +
Sbjct: 456 FTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTH 515
Query: 533 IVSDVIRGIC 542
++ ++ IC
Sbjct: 516 LLENLRGSIC 525
Score = 89.4 bits (220), Expect = 8e-18
Identities = 54/169 (31%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 144 PTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPH 203
P G++L+ + ++ D+ L+DGS ++ + F L K FV ++ L + EG
Sbjct: 324 PEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTR 383
Query: 204 VGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR 263
VGLVQ S + EF L + +A +V A+ V + + TG AL+H + F+ G R
Sbjct: 384 VGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGAR 443
Query: 264 K---GIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEEL 309
+P+V +VF DG DDI A+E G+ ++ V V K + EL
Sbjct: 444 PRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAEL 492
Score = 81.6 bits (200), Expect = 2e-15
Identities = 53/187 (28%), Positives = 88/187 (47%), Gaps = 5/187 (2%)
Query: 346 LVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAK 405
L+Q T Q+ + +++ F+ID S SV F M +F+ + + + +
Sbjct: 13 LLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATR 72
Query: 406 IAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIR--- 462
+ +Q++ ++ F +S +E++ IR++ ++ GT TG AI + + F
Sbjct: 73 VGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGAR 132
Query: 463 --ESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESH 520
E VIVTDG+ D V AA A GI I++VGV A + L+ MAS P + H
Sbjct: 133 PPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEH 192
Query: 521 AFFTREF 527
F F
Sbjct: 193 VFLVESF 199
Score = 66.2 bits (160), Expect = 7e-11
Identities = 39/142 (27%), Positives = 71/142 (50%), Gaps = 3/142 (2%)
Query: 165 DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTS 224
D+ F+ID S ++ F + F+ + L +G VG++Q S + F L+ F+
Sbjct: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
Query: 225 AKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR---KGIPKVVVVFIDGWPSDD 281
+D+ AI+++ + TG A+++ F+V G R + +P+V V+ DG P D
Sbjct: 94 REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
Query: 282 IEEAGIVAREFGVNVFIVSVAK 303
+ E AR G+ ++ V V +
Sbjct: 154 VAEVAAQARARGIEIYAVGVQR 175
>gi|38348304 von Willebrand factor A domain containing 2 [Homo
sapiens]
Length = 725
Score = 94.7 bits (234), Expect = 2e-19
Identities = 55/183 (30%), Positives = 92/183 (50%), Gaps = 3/183 (1%)
Query: 344 KPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIG 403
K + K+ +MM C +V+I FL+DGS+SVG +F F + +IS
Sbjct: 31 KETIGKISAASKMMW---CSAAVDIMFLLDGSNSVGKGSFERSKHFAITVCDGLDISPER 87
Query: 404 AKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRE 463
++ A QF+ EF +ST++ V A I+ + + G T T A+ + + R
Sbjct: 88 VRVGAFQFSSTPHLEFPLDSFSTQQEVKARIKRMVFKGGRTETELALKYLLHRGLPGGRN 147
Query: 464 SPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFF 523
+ L+IVTDG+S DV P+ + G+T+F+VGV + ++L +AS+P+ H
Sbjct: 148 ASVPQILIIVTDGKSQGDVALPSKQLKERGVTVFAVGVRFPRWEELHALASEPRGQHVLL 207
Query: 524 TRE 526
+
Sbjct: 208 AEQ 210
Score = 90.5 bits (223), Expect = 4e-18
Identities = 87/362 (24%), Positives = 157/362 (43%), Gaps = 19/362 (5%)
Query: 161 DCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLK 220
+C+ D+ FL+D S F K FV + + VG+ S + +
Sbjct: 339 ECRVDLLFLLDSSAGTTLDGFLRAKVFVKRFVRAVLSEDSRARVGVATYSRELLVAVPVG 398
Query: 221 NFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSD 280
+ D+++++ + FRGG + TG AL+ A++ F + P+ VVV + S+
Sbjct: 399 EYQDVPDLVWSLDGIPFRGGPTLTGSALRQAAERGFGSATRTGQDRPRRVVVLLTESHSE 458
Query: 281 DIEEAGIVAREFGVNVFIVSV-AKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGT 339
D E AG + ++ V ++ + EL +++T K V Y P
Sbjct: 459 D-EVAGPARHARARELLLLGVGSEAVRAEL---EEITGSPKHV------MVYSDPQ--DL 506
Query: 340 TKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEI 399
+ L KLC+ ++ C ++++ F++D S+SVG NF M FV + A FE+
Sbjct: 507 FNQIPELQGKLCSRQRPGCRT---QALDLVFMLDTSASVGPENFAQMQSFVRSCALQFEV 563
Query: 400 SDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFG 459
+ ++ V + +T F T+ +L I Y+ G + G A+ V
Sbjct: 564 NPDVTQVGLVVYGSQVQTAFGLDTKPTRAAMLRAISQAPYLGGVGSAGTALLHIYDKVMT 623
Query: 460 PIRESPN--KNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPK 517
R + +V++T G+ +D PA + GI++ VGV + L+ +A P+
Sbjct: 624 VQRGARPGVPKAVVVLTGGRGAEDAAVPAQKLRNNGISVLVVGVGPVLSEGLRRLAG-PR 682
Query: 518 ES 519
+S
Sbjct: 683 DS 684
Score = 82.4 bits (202), Expect = 1e-15
Identities = 56/172 (32%), Positives = 84/172 (48%), Gaps = 8/172 (4%)
Query: 165 DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTS 224
DI FL+DGS ++G+ F K+F V L I E VG Q S P +EF L +F++
Sbjct: 51 DIMFLLDGSNSVGKGSFERSKHFAITVCDGLDISPERVRVGAFQFSSTPHLEFPLDSFST 110
Query: 225 AKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDIEE 284
++V IK + F+GG + T ALK+ + + G +P+++++ DG D+
Sbjct: 111 QQEVKARIKRMVFKGGRTETELALKYLLHR--GLPGGRNASVPQILIIVTDGKSQGDVAL 168
Query: 285 AGIVAREFGVNVFIVSVAKPIPEELGMV------QDVTFVDKAVCRNNGFFS 330
+E GV VF V V P EEL + Q V ++ NG FS
Sbjct: 169 PSKQLKERGVTVFAVGVRFPRWEELHALASEPRGQHVLLAEQVEDATNGLFS 220
Score = 75.1 bits (183), Expect = 2e-13
Identities = 47/160 (29%), Positives = 72/160 (45%)
Query: 150 KKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQA 209
K ++ G + D+ F++D S ++G F ++FV AL + + VGLV
Sbjct: 516 KLCSRQRPGCRTQALDLVFMLDTSASVGPENFAQMQSFVRSCALQFEVNPDVTQVGLVVY 575
Query: 210 SEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKV 269
+ F L + +L AI + + GG + G AL H K TV G R G+PK
Sbjct: 576 GSQVQTAFGLDTKPTRAAMLRAISQAPYLGGVGSAGTALLHIYDKVMTVQRGARPGVPKA 635
Query: 270 VVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEEL 309
VVV G ++D R G++V +V V + E L
Sbjct: 636 VVVLTGGRGAEDAAVPAQKLRNNGISVLVVGVGPVLSEGL 675
>gi|11321565 matrilin 3 precursor [Homo sapiens]
Length = 486
Score = 89.4 bits (220), Expect = 8e-18
Identities = 58/182 (31%), Positives = 88/182 (48%), Gaps = 5/182 (2%)
Query: 366 VNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYS 425
+++ F+ID S SV F + FVS I T +I ++A V + + EF Y+
Sbjct: 82 LDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQLQAYT 141
Query: 426 TKENVLAVIRNIRYMSGGTATGDAISFTVRNVF----GPIRESPN-KNFLVIVTDGQSYD 480
K+++ + I +S GT +G AI + F G S N +IVTDG+ D
Sbjct: 142 DKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTDGRPQD 201
Query: 481 DVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRG 540
V AA A +GI +++VGV A + LK MAS+P E H F+ + +E + S
Sbjct: 202 QVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSSRFQET 261
Query: 541 IC 542
C
Sbjct: 262 FC 263
Score = 75.9 bits (185), Expect = 9e-14
Identities = 55/205 (26%), Positives = 92/205 (44%), Gaps = 18/205 (8%)
Query: 153 PEKKTGNKDCKA---DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQA 209
P + G CK+ D+ F+ID S ++ F K FV ++ L IG V +V
Sbjct: 68 PGRARGAGVCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNY 127
Query: 210 SEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRK---GI 266
+ KIEF L+ +T + + A+ + + +G A++ + FTV+AG R+ I
Sbjct: 128 ASTVKIEFQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNI 187
Query: 267 PKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSV------------AKPIPEELGMVQD 314
PKV ++ DG P D + E A+ G+ ++ V V ++P+ E + V+
Sbjct: 188 PKVAIIVTDGRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVET 247
Query: 315 VTFVDKAVCRNNGFFSYHMPNWFGT 339
++K R F P GT
Sbjct: 248 YGVIEKLSSRFQETFCALDPCVLGT 272
>gi|40068485 von Willebrand factor A domain containing 1 isoform 1
[Homo sapiens]
Length = 445
Score = 79.3 bits (194), Expect = 8e-15
Identities = 44/141 (31%), Positives = 71/141 (50%)
Query: 163 KADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNF 222
+ D+ FL+D S ++ F+ + FVG++ L +GT LV P EF
Sbjct: 32 RGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQH 91
Query: 223 TSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDI 282
+S + A++ R G+++TG AL + ++ F +G R G+PKV+V DG SD +
Sbjct: 92 SSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPV 151
Query: 283 EEAGIVAREFGVNVFIVSVAK 303
++ GV VFIVS +
Sbjct: 152 GPPMQELKDLGVTVFIVSTGR 172
Score = 66.2 bits (160), Expect = 7e-11
Identities = 54/186 (29%), Positives = 77/186 (41%), Gaps = 4/186 (2%)
Query: 367 NIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYST 426
++ FL+D S+SV F + EFV + + + + V TEF F +S+
Sbjct: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
Query: 427 KENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPN--KNFLVIVTDGQSYDDVQG 484
E +R G T TG A+ + +F + LV VTDG S D V
Sbjct: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPVGP 153
Query: 485 PAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGICRD 544
P D G+T+F V +L AS P E H F + L IV + +RG D
Sbjct: 154 PMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFV-DVDDLHIIVQE-LRGSILD 211
Query: 545 FLESQQ 550
+ QQ
Sbjct: 212 AMRPQQ 217
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 79.0 bits (193), Expect = 1e-14
Identities = 53/179 (29%), Positives = 88/179 (49%), Gaps = 16/179 (8%)
Query: 367 NIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYST 426
+I FLIDGS S+ NF M+ FV + F+ + + +QF+ +T F+F ++
Sbjct: 151 DIVFLIDGSGSISSRNFATMMNFVRAVISQFQRP--STQFSLMQFSNKFQTHFTFEEFRR 208
Query: 427 KENVLAVIRNIRYMSGGTATGDAISFTVRNVF----GPIRESPNKNFLVIVTDGQSYD-- 480
N L+++ ++ + G T T AI V +F G R++ L+++TDG+
Sbjct: 209 SSNPLSLLASVHQLQGFTYTATAIQNVVHRLFHASYGARRDA--AKILIVITDGKKEGDS 266
Query: 481 -DVQGPAAAAHDAGITIFSVGVAWA-----PLDDLKDMASKPKESHAFFTREFTGLEPI 533
D + A AGI +++GV A +L D+ASKP + H F +F L+ I
Sbjct: 267 LDYKDVIPMADAAGIIRYAIGVGLAFQNRNSWKELNDIASKPSQEHIFKVEDFDALKDI 325
Score = 50.4 bits (119), Expect = 4e-06
Identities = 43/170 (25%), Positives = 68/170 (40%), Gaps = 22/170 (12%)
Query: 165 DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTS 224
DI FLIDGS +I R F NFV A++ L+Q S + F + F
Sbjct: 151 DIVFLIDGSGSISSRNFATMMNFVR--AVISQFQRPSTQFSLMQFSNKFQTHFTFEEFRR 208
Query: 225 AKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDD--- 281
+ + L + V G + T A+++ + F G R+ K+++V DG D
Sbjct: 209 SSNPLSLLASVHQLQGFTYTATAIQNVVHRLFHASYGARRDAAKILIVITDGKKEGDSLD 268
Query: 282 -------IEEAGIVAREFGVNVFIVS----------VAKPIPEELGMVQD 314
+ AGI+ GV + + +KP E + V+D
Sbjct: 269 YKDVIPMADAAGIIRYAIGVGLAFQNRNSWKELNDIASKPSQEHIFKVED 318
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 76.3 bits (186), Expect = 7e-14
Identities = 55/176 (31%), Positives = 84/176 (47%), Gaps = 10/176 (5%)
Query: 366 VNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQ----RTEFSF 421
+ + FL+D SSSVG+ NFR L FV + F + ++A V F+ R ++
Sbjct: 82 LELVFLVDDSSSVGEVNFRSELMFVRKLLSDFPVVPTATRVAIVTFSSKNYVVPRVDYIS 141
Query: 422 TDYSTKEN---VLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIVTDGQS 478
T + + +L I I Y GGT T A + + RE+ K + ++TDG S
Sbjct: 142 TRRARQHKCALLLQEIPAISYRGGGTYTKGAFQQAAQ-ILLHARENSTK-VVFLITDGYS 199
Query: 479 YDDVQGPAAAA-HDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPI 533
P AA+ D+G+ IF+ G+ + +L DMAS PKE H + F E +
Sbjct: 200 NGGDPRPIAASLRDSGVEIFTFGIWQGNIRELNDMASTPKEEHCYLLHSFEEFEAL 255
Score = 38.1 bits (87), Expect = 0.021
Identities = 32/147 (21%), Positives = 61/147 (41%), Gaps = 12/147 (8%)
Query: 163 KADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEH----PKIEFY 218
+ ++ FL+D S ++G+ F + FV K+ + V +V S P++++
Sbjct: 81 RLELVFLVDDSSSVGEVNFRSELMFVRKLLSDFPVVPTATRVAIVTFSSKNYVVPRVDYI 140
Query: 219 LKNFTSAKDVLFAIKE---VGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFID 275
++E + +RGG + T A + AQ + R+ KVV + D
Sbjct: 141 STRRARQHKCALLLQEIPAISYRGGGTYTKGAFQQAAQ----ILLHARENSTKVVFLITD 196
Query: 276 GWPS-DDIEEAGIVAREFGVNVFIVSV 301
G+ + D R+ GV +F +
Sbjct: 197 GYSNGGDPRPIAASLRDSGVEIFTFGI 223
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 75.9 bits (185), Expect = 9e-14
Identities = 55/178 (30%), Positives = 86/178 (48%), Gaps = 14/178 (7%)
Query: 367 NIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYST 426
+IAFLIDGS S+ +FR M EFVS + + + S + +Q++ + R F+F ++
Sbjct: 150 DIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSK--TLFSLMQYSEEFRIHFTFKEFQN 207
Query: 427 KENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKN---FLVIVTDGQSYDDVQ 483
N ++++ I + G T T I VR +F I KN LV++TDG+ + D
Sbjct: 208 NPNPRSLVKPITQLLGRTHTATGIRKVVRELFN-ITNGARKNAFKILVVITDGEKFGDPL 266
Query: 484 GPAAAAHDA---GITIFSVGVAWA-----PLDDLKDMASKPKESHAFFTREFTGLEPI 533
G +A G+ + +GV A +L +ASKP H F F L+ I
Sbjct: 267 GYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTI 324
Score = 57.0 bits (136), Expect = 4e-08
Identities = 40/127 (31%), Positives = 59/127 (46%), Gaps = 2/127 (1%)
Query: 150 KKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQA 209
+K PE G +DIAFLIDGS +I F K FV V M + L+Q
Sbjct: 135 QKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTV--MEQLKKSKTLFSLMQY 192
Query: 210 SEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKV 269
SE +I F K F + + +K + G ++T ++ ++ F + G RK K+
Sbjct: 193 SEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKI 252
Query: 270 VVVFIDG 276
+VV DG
Sbjct: 253 LVVITDG 259
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,607,567
Number of Sequences: 37866
Number of extensions: 911438
Number of successful extensions: 2392
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1960
Number of HSP's gapped (non-prelim): 201
length of query: 550
length of database: 18,247,518
effective HSP length: 107
effective length of query: 443
effective length of database: 14,195,856
effective search space: 6288764208
effective search space used: 6288764208
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.