BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|47132587 protein kinase C, delta binding protein [Homo sapiens] (261 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|47132587 protein kinase C, delta binding protein [Homo sapiens] 506 e-143 gi|4759082 serum deprivation response protein [Homo sapiens] 135 5e-32 gi|42734430 polymerase I and transcript release factor [Homo sap... 103 2e-22 gi|66472922 muscle-related coiled-coil protein [Homo sapiens] 83 2e-16 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 47 2e-05 gi|17136078 VGF nerve growth factor inducible precursor [Homo sa... 46 3e-05 gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] 45 5e-05 gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 44 1e-04 gi|54860079 nadrin isoform 1 [Homo sapiens] 43 2e-04 gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 43 3e-04 gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 43 3e-04 gi|54860105 nadrin isoform 2 [Homo sapiens] 42 4e-04 gi|4557853 transcription factor SOX9 [Homo sapiens] 42 5e-04 gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 41 0.001 gi|194248095 epsin 1 isoform b [Homo sapiens] 41 0.001 gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 41 0.001 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 41 0.001 gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 40 0.002 gi|226498192 atonal homolog 8 [Homo sapiens] 40 0.003 gi|90903231 huntingtin [Homo sapiens] 40 0.003 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 40 0.003 gi|55750053 atrophin-1 [Homo sapiens] 40 0.003 gi|55750041 atrophin-1 [Homo sapiens] 40 0.003 gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 40 0.003 gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens] 40 0.003 gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 40 0.003 gi|41322923 plectin 1 isoform 11 [Homo sapiens] 39 0.003 gi|41322914 plectin 1 isoform 10 [Homo sapiens] 39 0.003 gi|41322919 plectin 1 isoform 8 [Homo sapiens] 39 0.003 gi|41322910 plectin 1 isoform 7 [Homo sapiens] 39 0.003 >gi|47132587 protein kinase C, delta binding protein [Homo sapiens] Length = 261 Score = 506 bits (1302), Expect = e-143 Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MRESALERGPVPEAPAGGPVHAVTVVTLLEKLASMLETLRERQGGLARRQGGLAGSVRRI 60 MRESALERGPVPEAPAGGPVHAVTVVTLLEKLASMLETLRERQGGLARRQGGLAGSVRRI Sbjct: 1 MRESALERGPVPEAPAGGPVHAVTVVTLLEKLASMLETLRERQGGLARRQGGLAGSVRRI 60 Query: 61 QSGLGALSRSHDTTSNTLAQLLAKAERVSSHANAAQERAVRRAAQVQRLEANHGLLVARG 120 QSGLGALSRSHDTTSNTLAQLLAKAERVSSHANAAQERAVRRAAQVQRLEANHGLLVARG Sbjct: 61 QSGLGALSRSHDTTSNTLAQLLAKAERVSSHANAAQERAVRRAAQVQRLEANHGLLVARG 120 Query: 121 KLHVLLFKEEGEVPASAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRR 180 KLHVLLFKEEGEVPASAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRR Sbjct: 121 KLHVLLFKEEGEVPASAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRR 180 Query: 181 TGLQKVQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDT 240 TGLQKVQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDT Sbjct: 181 TGLQKVQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDT 240 Query: 241 EEDPGRPGAAEEALLQMESVA 261 EEDPGRPGAAEEALLQMESVA Sbjct: 241 EEDPGRPGAAEEALLQMESVA 261 >gi|4759082 serum deprivation response protein [Homo sapiens] Length = 425 Score = 135 bits (339), Expect = 5e-32 Identities = 79/195 (40%), Positives = 119/195 (61%), Gaps = 20/195 (10%) Query: 20 VHAVTVVTLLEKLASMLETLRERQGGLARRQGGLAGSVRRIQSGLGALSRSHDTTSNTLA 79 V+AVTV+TLL+KL +ML+ ++E Q + +RQ L GSV+ IQ+ L LS+ +TSNT++ Sbjct: 53 VNAVTVLTLLDKLVNMLDAVQENQHKMEQRQISLEGSVKGIQNDLTKLSKYQASTSNTVS 112 Query: 80 QLLAKAERVSSHANAAQERAVRRAAQVQRLEANHGLLVARGKLHVLLFKEEGEVPASAFQ 139 +LL K+ +VS+H A +ER R+ AQV+RLE NH L+ R VL+F+EE E+PAS F Sbjct: 113 KLLEKSRKVSAHTRAVKERMDRQCAQVKRLENNHAQLLRRNHFKVLIFQEENEIPASVFV 172 Query: 140 KAPEPLGPADQSELGPEQLEAE--------------------VGESSDEEPVESRAQRLR 179 K P + EL E E + +S++E+ ESRA++++ Sbjct: 173 KQPVSGAVEGKEELPDENKSLEETLHTVDLSSDDDLPHDEEALEDSAEEKVEESRAEKIK 232 Query: 180 RTGLQKVQSLRRALS 194 R+ L+KV SL++A S Sbjct: 233 RSSLKKVDSLKKAFS 247 >gi|42734430 polymerase I and transcript release factor [Homo sapiens] Length = 390 Score = 103 bits (256), Expect = 2e-22 Identities = 67/192 (34%), Positives = 110/192 (57%), Gaps = 14/192 (7%) Query: 20 VHAVTVVTLLEKLASMLETLRERQGGLARRQGGLAGSVRRIQSGLGALSRSHDTTSNTLA 79 V+ V V++LL+K+ ++ ++ Q L RQ + G+V+ IQ L L ++H TTSNT++ Sbjct: 49 VNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVS 108 Query: 80 QLLAKAERVSSHANAAQERAVRRAAQVQRLEANHGLLVARGKLHVLLFKEEGEVPA---- 135 +LL K +VS + + R+A Q+++LE N L+ R V+++++E ++PA Sbjct: 109 KLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSI 168 Query: 136 SAFQKAPEPLGPADQSELG----PEQLEAEVGESSDE----EPV--ESRAQRLRRTGLQK 185 S K E L + ELG PE+ A + SSDE E V ESRA+R++R+GL++ Sbjct: 169 SKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRR 228 Query: 186 VQSLRRALSGRK 197 V ++A S K Sbjct: 229 VDDFKKAFSKEK 240 >gi|66472922 muscle-related coiled-coil protein [Homo sapiens] Length = 364 Score = 83.2 bits (204), Expect = 2e-16 Identities = 49/175 (28%), Positives = 97/175 (55%), Gaps = 3/175 (1%) Query: 22 AVTVVTLLEKLASMLETLRERQGGLARRQGGLAGSVRRIQSGLGALSRSHDTTSNTLAQL 81 A+T+VT+L+K+AS++++++ Q + R + +++ +Q L LS+SH T + + +L Sbjct: 30 ALTIVTVLDKVASIVDSVQASQKRIEERHREMENAIKSVQIDLLKLSQSHSNTGHIINKL 89 Query: 82 LAKAERVSSHANAAQERAVRRAAQVQRLEANHGLLVARGKLHVLLFKEEGEVPASAFQKA 141 K +VS+H + R ++ V+++E ++ + K V++F+E+ P S Sbjct: 90 FEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVK 149 Query: 142 PEPLGPADQSELGPEQLEAEVGESSDEE--PVESRAQRLRRTGLQKVQSLRRALS 194 L +Q E + + V SSDEE ESR+ RLR++G + + ++++A S Sbjct: 150 DRNL-TENQEEDDDDIFDPPVDLSSDEEYYVEESRSARLRKSGKEHIDNIKKAFS 203 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 46.6 bits (109), Expect = 2e-05 Identities = 46/133 (34%), Positives = 61/133 (45%), Gaps = 16/133 (12%) Query: 127 FKEEGEVPASAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRTGLQKV 186 F+EE E F++ E + E E+ E E GE +EE E + L++V Sbjct: 910 FEEEEEDEEEYFEEEEE------EEEEFEEEFEEEEGELEEEEEEEDEEEEEE---LEEV 960 Query: 187 QSLRRALSGRK-GPAAPPPTPVKPPRLGPGRS-AEAQPEAQPALEPTLEPEPPQDTEEDP 244 + L +G + APPP P PP L P S + QPE +P LE E P TEE+ Sbjct: 961 EDLEFGTAGGEVEEGAPPP-PTLPPALPPPESPPKVQPEPEPEPGLLLEVEEP-GTEEER 1018 Query: 245 G---RPGAAEEAL 254 G P A EAL Sbjct: 1019 GADTAPTLAPEAL 1031 Score = 34.3 bits (77), Expect = 0.11 Identities = 16/40 (40%), Positives = 18/40 (45%) Query: 198 GPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPP 237 G PP P PP P A+ +PE PA L P PP Sbjct: 805 GATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPP 844 Score = 30.8 bits (68), Expect = 1.2 Identities = 37/125 (29%), Positives = 45/125 (36%), Gaps = 12/125 (9%) Query: 129 EEGEVPASAFQKA--PEPLGPADQSELGPEQ-LEAEVGE-SSDEEPVESRAQRLRRTGLQ 184 EEG P A P P Q E PE L EV E ++EE A L L Sbjct: 973 EEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALP 1032 Query: 185 KVQSLRRALSGRKGPAAPPPT------PVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQ 238 + R G A PPP P PP L + + + QP E E E Sbjct: 1033 SQGEVER--EGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMET 1090 Query: 239 DTEED 243 +TE + Sbjct: 1091 ETEAE 1095 Score = 28.5 bits (62), Expect = 6.2 Identities = 18/52 (34%), Positives = 20/52 (38%), Gaps = 8/52 (15%) Query: 199 PAAPPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPP--QDTEEDPGRPG 248 P PP P PP S P P PT P P ++ EE P PG Sbjct: 792 PEGLPPLPPPPP------SGATPPPIAPTGPPTASPPVPAKEEPEELPAAPG 837 >gi|17136078 VGF nerve growth factor inducible precursor [Homo sapiens] Length = 615 Score = 46.2 bits (108), Expect = 3e-05 Identities = 51/209 (24%), Positives = 74/209 (35%), Gaps = 20/209 (9%) Query: 53 LAGSVRRIQSGLGALSRSHDTTSNTLAQLLAKAERVSSHANAAQERAVRRAAQVQRLEAN 112 L G R+ G L + + + + A+ ER +E A+ + EA Sbjct: 337 LQGGARQRGLGGRGLQEAAEERESAREEEEAEQERRGGEERVGEEDEEAAEAEAEAEEAE 396 Query: 113 HGLLVARGKLHVLLFKEEGEVPASAFQKAPEPLGPAD---QSELGPEQLEAEVGESSDEE 169 R + + LLF EE + A A K + P ++E E E E E D + Sbjct: 397 ------RARQNALLFAEEEDGEAGAEDKRSQEETPGHRRKEAEGTEEGGEEEDDEEMDPQ 450 Query: 170 PVESRAQ---RLRRTGLQKVQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQP 226 ++S + +L V + RK PP PV PPR P + P+ P Sbjct: 451 TIDSLIELSTKLHLPADDVVSIIEEVEEKRKRKKNAPPEPVPPPRAAPAPTHVRSPQPPP 510 Query: 227 ALEPTLEPE--------PPQDTEEDPGRP 247 E PP D EED P Sbjct: 511 PAPAPARDELPDWNEVLPPWDREEDEVYP 539 Score = 28.5 bits (62), Expect = 6.2 Identities = 56/200 (28%), Positives = 78/200 (39%), Gaps = 26/200 (13%) Query: 10 PVPEAPAGGPVHAVTVVTLLEKLASMLETLRERQGGLARRQGGLAGSVRRIQSGLGALSR 69 P P+ P GP A LE LAS+L+ LR+ A+RQ A + +R Sbjct: 138 PRPQTPENGP-EASDPSEELEALASLLQELRDFSPSSAKRQQETAAAETE--------TR 188 Query: 70 SHDTTSNTLAQLLAKAERV-SSHANAAQERAVRRA-------AQVQRLEANHGLLVARGK 121 +H T L ERV + Q R RA +Q Q + G L K Sbjct: 189 THTLTRVNLES--PGPERVWRASWGEFQARVPERAPLPPPAPSQFQARMPDSGPLPETHK 246 Query: 122 LHVLLFKEEGEVPASAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRT 181 F E P + +A PL A Q P +A ES+ E+ +RL + Sbjct: 247 -----FGEGVSSPKTHLGEALAPLSKAYQGVAAPFP-KARRPESALLGGSEA-GERLLQQ 299 Query: 182 GLQKVQSLRRALSGRKGPAA 201 GL +V++ RR + AA Sbjct: 300 GLAQVEAGRRQAEATRQAAA 319 >gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] Length = 1243 Score = 45.4 bits (106), Expect = 5e-05 Identities = 36/117 (30%), Positives = 45/117 (38%), Gaps = 9/117 (7%) Query: 140 KAPEPLGPADQSELGPEQLEAE-VGESSDEEPVESRAQRLRRTGLQKVQSLRRALSGRKG 198 + P PLG A Q LGP A ++ P SR R L LS Sbjct: 23 RPPPPLGTAGQPRLGPPPRRARRFSGKAEPRPRSSRLSRRSSVDLG-------LLSSWSL 75 Query: 199 PAAPPPTPVKPP-RLGPGRSAEAQPEAQPALEPTLEPEPPQDTEEDPGRPGAAEEAL 254 PA+P P P PP GPG + P ++ E T P ED RP + A+ Sbjct: 76 PASPAPDPPDPPDSAGPGPARSPPPSSKEPPEGTWTEGAPVKAAEDSARPELPDSAV 132 Score = 30.0 bits (66), Expect = 2.1 Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 16/104 (15%) Query: 145 LGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRTGLQ-KVQSLRRALSGRKGPAAPP 203 LG E+ E + + +D +PV +RA R R +Q K + LR+A P P Sbjct: 480 LGRDAAEEVAQEMVALGLVCEADYQPV-ARAVRERVAAIQRKREKLRKARELEALPPEPG 538 Query: 204 PTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDTEEDPGRP 247 P P P + PG P++ P P++ E D +P Sbjct: 539 PPPATVP-MAPG-------------PPSVFPPEPEEPEADQHQP 568 >gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] Length = 825 Score = 44.3 bits (103), Expect = 1e-04 Identities = 37/131 (28%), Positives = 60/131 (45%), Gaps = 12/131 (9%) Query: 132 EVPASAFQKAPEPLGPADQSELGPEQLEAEV--GESSDEEPVESRAQRLRRTGLQKVQSL 189 E PA +A PL +E P ++++ G S +E P+E + T ++ + Sbjct: 537 ETPA----EAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAA 592 Query: 190 RRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDTEEDPG--RP 247 + L+ + A P V+PP P A A+ + PA E E +PP EE P +P Sbjct: 593 IQLLAATEASAEEAPAEVQPP---PAEEAPAEVQPPPAEEAPAEVQPP-PAEEAPAEVQP 648 Query: 248 GAAEEALLQME 258 AEEA +++ Sbjct: 649 PPAEEAPAEVQ 659 Score = 31.6 bits (70), Expect = 0.73 Identities = 29/127 (22%), Positives = 51/127 (40%), Gaps = 12/127 (9%) Query: 137 AFQKAPEPLGPADQSELGPEQLEAEVGE-SSDEEPVESRAQRLRRTGLQKVQSLRRALSG 195 + ++AP L P E E+ A + ++ E E ++ ++ + + Sbjct: 568 SIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPA 627 Query: 196 RKGPAA--PPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDTEEDPGRPGAAEEA 253 + PA PPP P + P + EA E QP PP + +P AEEA Sbjct: 628 EEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQP---------PPAEEAPAEVQPPPAEEA 678 Query: 254 LLQMESV 260 +++S+ Sbjct: 679 PAEVQSL 685 Score = 29.6 bits (65), Expect = 2.8 Identities = 28/110 (25%), Positives = 47/110 (42%), Gaps = 8/110 (7%) Query: 157 QLEAEVGESSDEEPVESRAQRLRRTGLQKVQSLRRALSGRKGPAAPPPTPVKPPRLGPGR 216 QL A + +DE P E+++ T ++ + ++ S + P ++PP Sbjct: 526 QLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETT 585 Query: 217 SAEAQPEAQ--PALEPTLEPEP----PQDTEEDPG--RPGAAEEALLQME 258 + EA Q A E + E P P EE P +P AEEA +++ Sbjct: 586 AEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQ 635 >gi|54860079 nadrin isoform 1 [Homo sapiens] Length = 881 Score = 43.1 bits (100), Expect = 2e-04 Identities = 34/137 (24%), Positives = 55/137 (40%), Gaps = 21/137 (15%) Query: 129 EEGEVPASAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVESRAQRL-----RRTGL 183 E+G P P+P P + P + +++ ++ + + +L Sbjct: 566 EQGPSPGDG--SPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAG 623 Query: 184 QKVQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPP------ 237 +LRRA+ K PA PP P PP PG + + P P+L P+PP Sbjct: 624 PSPHTLRRAV---KKPAPAPPKPGNPPPGHPGGQSSSGTSQHP---PSLSPKPPTRSPSP 677 Query: 238 --QDTEEDPGRPGAAEE 252 Q T + PG+P A + Sbjct: 678 PTQHTGQPPGQPSAPSQ 694 >gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] Length = 1120 Score = 42.7 bits (99), Expect = 3e-04 Identities = 44/154 (28%), Positives = 61/154 (39%), Gaps = 29/154 (18%) Query: 125 LLFKEEGEVPASAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRTGLQ 184 L F EEG + ++ P+P GP + P L+ + ES + V+ R + R LQ Sbjct: 868 LPFAEEGNL---TIKQRPKPAGPPPRETPVPPGLDFNLTES---DTVKRRPKCREREPLQ 921 Query: 185 KVQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPE--------------AQPALEP 230 S GPAAP P+P P P S+ QPE PA++P Sbjct: 922 TALLAFGVASATPGPAAPLPSPT--PGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQP 979 Query: 231 TLEPEPPQDTEEDPG-------RPGAAEEALLQM 257 + P P E P AA ALL++ Sbjct: 980 PVPPCPGPGLESSAASRWNGETEPPAAPAALLKV 1013 Score = 32.0 bits (71), Expect = 0.56 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%) Query: 193 LSGRKGPA-APPPTPVKPPRLGPGRSAEAQPEAQPALEPTLE-PEPPQDTEEDPGRPGAA 250 L+ R GP PPP P +GPG++ + + +L L E T+E G P A+ Sbjct: 1037 LAPRLGPRPVPPPRPESTGTVGPGQAQQRLEQTSSSLAAALRAAEKSIGTKEQEGTPSAS 1096 Query: 251 EEALL 255 + +L Sbjct: 1097 TKHIL 1101 Score = 31.6 bits (70), Expect = 0.73 Identities = 30/98 (30%), Positives = 39/98 (39%), Gaps = 16/98 (16%) Query: 155 PEQLEAEVGESSDEEPV-ESRAQRLRRTGLQKVQSLRRALSGRKGPAAPPPTPVKPPRLG 213 P++L + G S + P+ ES + TG + RR LS GP+ PP P G Sbjct: 791 PKRLSSVSGPSPEPPPLDESPGPKEGATGPR-----RRTLSEPAGPSEPPGPPAP---AG 842 Query: 214 PGRSAEAQPEAQPALEPTLEPEPPQDTEEDPGRPGAAE 251 P E + EP E PP G P A E Sbjct: 843 PASDTEEE-------EPGPEGTPPSRGSSGEGLPFAEE 873 >gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] Length = 1202 Score = 42.7 bits (99), Expect = 3e-04 Identities = 44/154 (28%), Positives = 61/154 (39%), Gaps = 29/154 (18%) Query: 125 LLFKEEGEVPASAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRTGLQ 184 L F EEG + ++ P+P GP + P L+ + ES + V+ R + R LQ Sbjct: 950 LPFAEEGNL---TIKQRPKPAGPPPRETPVPPGLDFNLTES---DTVKRRPKCREREPLQ 1003 Query: 185 KVQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPE--------------AQPALEP 230 S GPAAP P+P P P S+ QPE PA++P Sbjct: 1004 TALLAFGVASATPGPAAPLPSPT--PGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQP 1061 Query: 231 TLEPEPPQDTEEDPG-------RPGAAEEALLQM 257 + P P E P AA ALL++ Sbjct: 1062 PVPPCPGPGLESSAASRWNGETEPPAAPAALLKV 1095 Score = 32.0 bits (71), Expect = 0.56 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%) Query: 193 LSGRKGPA-APPPTPVKPPRLGPGRSAEAQPEAQPALEPTLE-PEPPQDTEEDPGRPGAA 250 L+ R GP PPP P +GPG++ + + +L L E T+E G P A+ Sbjct: 1119 LAPRLGPRPVPPPRPESTGTVGPGQAQQRLEQTSSSLAAALRAAEKSIGTKEQEGTPSAS 1178 Query: 251 EEALL 255 + +L Sbjct: 1179 TKHIL 1183 Score = 31.6 bits (70), Expect = 0.73 Identities = 30/98 (30%), Positives = 39/98 (39%), Gaps = 16/98 (16%) Query: 155 PEQLEAEVGESSDEEPV-ESRAQRLRRTGLQKVQSLRRALSGRKGPAAPPPTPVKPPRLG 213 P++L + G S + P+ ES + TG + RR LS GP+ PP P G Sbjct: 873 PKRLSSVSGPSPEPPPLDESPGPKEGATGPR-----RRTLSEPAGPSEPPGPPAP---AG 924 Query: 214 PGRSAEAQPEAQPALEPTLEPEPPQDTEEDPGRPGAAE 251 P E + EP E PP G P A E Sbjct: 925 PASDTEEE-------EPGPEGTPPSRGSSGEGLPFAEE 955 >gi|54860105 nadrin isoform 2 [Homo sapiens] Length = 803 Score = 42.4 bits (98), Expect = 4e-04 Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 19/127 (14%) Query: 139 QKAPEPLGPADQSELGPEQLEAEVGESSDEEPVESRAQRL-----RRTGLQKVQSLRRAL 193 + P+P P + P + +++ ++ + + +L +LRRA+ Sbjct: 496 ESPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAV 555 Query: 194 SGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPP--------QDTEEDPG 245 K PA PP P PP PG + + P P+L P+PP Q T + PG Sbjct: 556 ---KKPAPAPPKPGNPPPGHPGGQSSSGTSQHP---PSLSPKPPTRSPSPPTQHTGQPPG 609 Query: 246 RPGAAEE 252 +P A + Sbjct: 610 QPSAPSQ 616 >gi|4557853 transcription factor SOX9 [Homo sapiens] Length = 509 Score = 42.0 bits (97), Expect = 5e-04 Identities = 17/38 (44%), Positives = 22/38 (57%) Query: 201 APPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQ 238 APPP P +PP+ P A QP+A P +P P+ PQ Sbjct: 341 APPPPPQQPPQAPPAPQAPPQPQAAPPQQPAAPPQQPQ 378 >gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens] Length = 2462 Score = 41.2 bits (95), Expect = 0.001 Identities = 37/130 (28%), Positives = 48/130 (36%), Gaps = 16/130 (12%) Query: 129 EEGEVPASAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVES-RAQRLRRTGLQKVQ 187 EE P + E G + E E+ EA V SSD E + S + + TG Sbjct: 692 EEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQ---- 747 Query: 188 SLRRALSGRKGPAA-----PPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDTEE 242 +G K PA PPP P PP E P ++ PT P PP + Sbjct: 748 ------NGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAP 801 Query: 243 DPGRPGAAEE 252 P P +E Sbjct: 802 PPVVPKEEKE 811 Score = 32.0 bits (71), Expect = 0.56 Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 4/82 (4%) Query: 165 SSDEEPVESRAQRLRRTGLQKVQSLRRALSGRK--GPAAP-PPTPVKPPRLGPGRSAEAQ 221 +S ++P++ + + R + +Q + R+ P P PP P P L P A Q Sbjct: 938 ASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQ 997 Query: 222 PEAQPALEPTLEPEPPQDTEED 243 P + P + P PP D E + Sbjct: 998 PGSSPR-GKSRSPAPPADKEAE 1018 >gi|194248095 epsin 1 isoform b [Homo sapiens] Length = 576 Score = 41.2 bits (95), Expect = 0.001 Identities = 56/218 (25%), Positives = 82/218 (37%), Gaps = 38/218 (17%) Query: 56 SVRRIQSGLGALSRSHDTTSNTLAQLLAKAERVSSHANAAQERAVRRAAQVQRLEA---N 112 +VR L AL R D A L E+++ A A+ AV + +A + Sbjct: 122 NVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSA-AVGSGPPPEAEQAWPQS 180 Query: 113 HGLLVARGKLHVLLFKEEGEVPASAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVE 172 G + +L + + KEE + P S GP D + QL+ + S +E E Sbjct: 181 SGEEELQLQLALAMSKEEADQPPSC--------GPEDDA-----QLQLALSLSREEHDKE 227 Query: 173 SRAQRLRRTGLQK-VQSLRRALSGRKGPA---------APPPTPVKPPRLGPGRSAEAQP 222 R +R LQ ++ +R G++ + AP P P P GP A A P Sbjct: 228 ERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVP 287 Query: 223 EAQPALEPTLEPEPPQDTEE-----------DPGRPGA 249 A P +P P P + DP RP A Sbjct: 288 TAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAA 325 >gi|62000702 diacylglycerol kinase kappa [Homo sapiens] Length = 1271 Score = 41.2 bits (95), Expect = 0.001 Identities = 35/110 (31%), Positives = 44/110 (40%), Gaps = 3/110 (2%) Query: 134 PASAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRTGLQKVQSLRRAL 193 P A + A EP P +E PE E + E ES + L+ V L Sbjct: 83 PEPATEPASEP-APEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPEL 141 Query: 194 SGRKGPA-APPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDTEE 242 + P AP PTP L P EA PE +P+ P L + P DT E Sbjct: 142 TPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCL-LQCPVDTRE 190 Score = 36.6 bits (83), Expect = 0.023 Identities = 21/55 (38%), Positives = 24/55 (43%), Gaps = 10/55 (18%) Query: 200 AAPPPTPVKPPRLGPGRSAEA----------QPEAQPALEPTLEPEPPQDTEEDP 244 A+P P P P L PG EA +P +PA EP EP P TE P Sbjct: 49 ASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAP 103 Score = 35.8 bits (81), Expect = 0.039 Identities = 31/116 (26%), Positives = 42/116 (36%), Gaps = 7/116 (6%) Query: 129 EEGEVPASAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRTGLQKVQS 188 ++GE PA + + P P P P + E+S E P+ L + S Sbjct: 15 QDGEQPAESPE--PPPPWPPPPPPPAPPPAPPLLSEASPE-PIPEPCPELAPGPCPEATS 71 Query: 189 LRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDTEEDP 244 S + P P P P P +P +PA EP EP P TE P Sbjct: 72 E----SATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAP 123 Score = 32.0 bits (71), Expect = 0.56 Identities = 30/112 (26%), Positives = 39/112 (34%), Gaps = 8/112 (7%) Query: 134 PASAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRTGLQKVQSLRRAL 193 P + +PEP+ P EL P ES+ E E + + A Sbjct: 43 PPLLSEASPEPI-PEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEP------AP 95 Query: 194 SGRKGPAAPPPT-PVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDTEEDP 244 PA P T P P P + +P +PALE EP P E P Sbjct: 96 EPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAP 147 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 41.2 bits (95), Expect = 0.001 Identities = 33/119 (27%), Positives = 50/119 (42%), Gaps = 4/119 (3%) Query: 130 EGEVPASAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVESR----AQRLRRTGLQK 185 EGE + +APE G A G E EAE + E VE++ + G++ Sbjct: 2107 EGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEA 2166 Query: 186 VQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDTEEDP 244 ++ A +G AP P + EA+ EAQP LE PE ++ + +P Sbjct: 2167 QEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEP 2225 Score = 35.0 bits (79), Expect = 0.066 Identities = 35/127 (27%), Positives = 50/127 (39%), Gaps = 7/127 (5%) Query: 130 EGEV-PASAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRT----GLQ 184 EGE P S +APE G A G E +AE + E +E++ G++ Sbjct: 2122 EGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVE 2181 Query: 185 KVQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDTEEDP 244 ++ A +G AP P L + EA+ EAQP EP P + E P Sbjct: 2182 APEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQP--EPEGVETPEAEGEAQP 2239 Query: 245 GRPGAAE 251 G + Sbjct: 2240 ESEGETQ 2246 Score = 33.5 bits (75), Expect = 0.19 Identities = 40/123 (32%), Positives = 51/123 (41%), Gaps = 17/123 (13%) Query: 130 EGEV-PASAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRTGLQKVQS 188 EGE P S +APE G A G E EAE + E VE+ G + +S Sbjct: 2186 EGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAE----GEAQPES 2241 Query: 189 LRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALE--PTLEPEPPQDTEEDPGR 246 +KG +P + LG G+S EA + P E PT P P DT R Sbjct: 2242 EGETQGEKKG--SPQVS------LGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQ--R 2291 Query: 247 PGA 249 PG+ Sbjct: 2292 PGS 2294 Score = 29.6 bits (65), Expect = 2.8 Identities = 39/145 (26%), Positives = 54/145 (37%), Gaps = 31/145 (21%) Query: 128 KEEGEVPASAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRTGLQKVQ 187 ++ G+ + +APE G A G E EAE D + E AQ + Sbjct: 1824 QDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAE----GDAQEAEGEAQP---------E 1870 Query: 188 SLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDT------- 240 S +G A P V+ P E QPE++ A P E E +T Sbjct: 1871 SEDVEAPEAEGEAQPESEDVETPEA----EWEVQPESEGAEAPEAEKEAQPETESVEALE 1926 Query: 241 ---EEDPGRPGA----AEEALLQME 258 E++P GA AEEA + E Sbjct: 1927 TEGEDEPESEGAEAQEAEEAAQEAE 1951 Score = 29.3 bits (64), Expect = 3.6 Identities = 40/178 (22%), Positives = 69/178 (38%), Gaps = 11/178 (6%) Query: 84 KAERVSSHANAAQERAVRRAAQVQRLEANHGLLVARGKLHVLLFKEEGEVPASAFQKAPE 143 + E V + ++ A+ Q EA A G+ + E EV S Q+A E Sbjct: 1918 ETESVEALETEGEDEPESEGAEAQ--EAEEAAQEAEGQT-----QPESEVIES--QEAEE 1968 Query: 144 PLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRTGLQKVQSLRRALSGRKGPAAPP 203 P + ++ ++E E E+ E ES + ++ A G A P Sbjct: 1969 EAQP-ESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQP 2027 Query: 204 PTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDTEEDPGRPGAAE-EALLQMESV 260 + + + G + + + +AQP + PE ++ +E G AE EA + E V Sbjct: 2028 KSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDV 2085 Score = 28.5 bits (62), Expect = 6.2 Identities = 40/174 (22%), Positives = 63/174 (36%), Gaps = 19/174 (10%) Query: 95 AQERAVRRAAQVQRLEANHGLLVARGKLH-----VLLFKEEGEVPASAFQKAPEPLGPAD 149 A+E A + V+ LE A G+ V + EGE+ + + PE G Sbjct: 1966 AEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEA 2025 Query: 150 QSELGPEQLEAEVGESS----DEEPVESRAQRLRRTGLQKVQSLRRALSGRKGPAAPPPT 205 Q + E+ + GE+ D +P + ++ Q + +G A P Sbjct: 2026 QPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAE--EEAQEAEGEVQEAEGEAHPESE 2083 Query: 206 PVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDTEEDPGRPGAAEEALLQMES 259 V + EA+ EAQP E PE + ++ G E Q ES Sbjct: 2084 DVD--------AQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPES 2129 >gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] Length = 1003 Score = 40.0 bits (92), Expect = 0.002 Identities = 25/61 (40%), Positives = 29/61 (47%), Gaps = 3/61 (4%) Query: 188 SLRRALSGRKGPAAPPPTPVKPPRLGPGRS-AEAQPEAQPALEPTLEPEPPQDTEEDPGR 246 SL L+G G PPP P+ PP GPG A +PE L +L P PP D P Sbjct: 559 SLFGVLTG--GGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSA 616 Query: 247 P 247 P Sbjct: 617 P 617 >gi|226498192 atonal homolog 8 [Homo sapiens] Length = 321 Score = 39.7 bits (91), Expect = 0.003 Identities = 50/187 (26%), Positives = 63/187 (33%), Gaps = 33/187 (17%) Query: 76 NTLAQLLAKAERVSSHANAAQERAVRRAAQVQRLEANHGLLVARGKLHVLLFKEEGEVPA 135 N L +L K + + AN + + A R A +GL R + H L P Sbjct: 21 NGLKKLKRKGKEPARRANGYKTFRLDLEAPEPRAVATNGL---RDRTHRLQ-------PV 70 Query: 136 SAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRTGLQKVQSLRRALSG 195 P P+ PA G + GE E R R L G Sbjct: 71 PVPVPVPVPVAPAVPPRGGTDT----AGERGGSRAPEVSDARKRCFAL-----------G 115 Query: 196 RKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPE------PPQDTEEDPGRPGA 249 GP P P P PP P A PEAQP EP L P P + P P A Sbjct: 116 AVGPGLPTPPPPPPP--APQSQAPGGPEAQPFREPGLRPRILLCAPPARPAPSAPPAPPA 173 Query: 250 AEEALLQ 256 E+ ++ Sbjct: 174 PPESTVR 180 >gi|90903231 huntingtin [Homo sapiens] Length = 3144 Score = 39.7 bits (91), Expect = 0.003 Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 10/86 (11%) Query: 169 EPVESRAQRLRRTGLQKVQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPAL 228 E ++S Q+ ++ Q+ Q ++ ++ P PPP P PP+L + P+AQP L Sbjct: 12 ESLKSFQQQQQQQQQQQQQQQQQQQQQQQPPPPPPPPP--PPQL-----PQPPPQAQPLL 64 Query: 229 EPTLEPEPPQDTEEDPGRPGAAEEAL 254 +P+PP P P AEE L Sbjct: 65 P---QPQPPPPPPPPPPGPAVAEEPL 87 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 39.7 bits (91), Expect = 0.003 Identities = 44/149 (29%), Positives = 62/149 (41%), Gaps = 17/149 (11%) Query: 112 NHGLLVARGKLHVLLFKEEGEVPASAFQKAPEPLGPA------DQSELGPEQLEAEVGES 165 N +V+ LH L ++ A P+P P Q+ L P+ A+ + Sbjct: 852 NQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQV 911 Query: 166 --SDEEP----VESRAQRLRRTGLQKVQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAE 219 DEEP + S +L LQKVQ L K + PPP + PP P S + Sbjct: 912 LLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPP-LPPP---PHPSVQ 967 Query: 220 AQPEAQPALEPTLEPE-PPQDTEEDPGRP 247 Q + QP P +P+ PPQ + P RP Sbjct: 968 QQLQQQPPPPPPPQPQPPPQQQHQPPPRP 996 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 39.7 bits (91), Expect = 0.003 Identities = 45/174 (25%), Positives = 71/174 (40%), Gaps = 17/174 (9%) Query: 89 SSHANAAQERAVRRAAQVQRLEANHGLLVARGKLHVLLFKEEGEVPA----SAFQKAPEP 144 SS A + R + A+V+ EA+ + +G+ + E E A Q+ P P Sbjct: 42 SSDGKAEKSRQTAKKARVE--EASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRP 99 Query: 145 LGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRTGLQKVQSLRRALSG-RKGPAAP- 202 P+D L L + + ++R+ V++ + SG +GPA P Sbjct: 100 QSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPY 159 Query: 203 PPTPVKPPRLGPGRSAEAQPEA----QPALEPT-----LEPEPPQDTEEDPGRP 247 P P+ PP P S QPEA P++ PT +EP + + PG P Sbjct: 160 HPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAP 213 Score = 28.1 bits (61), Expect = 8.1 Identities = 17/54 (31%), Positives = 22/54 (40%) Query: 184 QKVQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPP 237 Q+ Q ++ G + PPP P L G S A P A +L P PP Sbjct: 491 QQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPP 544 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 39.7 bits (91), Expect = 0.003 Identities = 45/174 (25%), Positives = 71/174 (40%), Gaps = 17/174 (9%) Query: 89 SSHANAAQERAVRRAAQVQRLEANHGLLVARGKLHVLLFKEEGEVPA----SAFQKAPEP 144 SS A + R + A+V+ EA+ + +G+ + E E A Q+ P P Sbjct: 42 SSDGKAEKSRQTAKKARVE--EASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRP 99 Query: 145 LGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRTGLQKVQSLRRALSG-RKGPAAP- 202 P+D L L + + ++R+ V++ + SG +GPA P Sbjct: 100 QSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPY 159 Query: 203 PPTPVKPPRLGPGRSAEAQPEA----QPALEPT-----LEPEPPQDTEEDPGRP 247 P P+ PP P S QPEA P++ PT +EP + + PG P Sbjct: 160 HPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAP 213 Score = 28.1 bits (61), Expect = 8.1 Identities = 17/54 (31%), Positives = 22/54 (40%) Query: 184 QKVQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPP 237 Q+ Q ++ G + PPP P L G S A P A +L P PP Sbjct: 491 QQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPP 544 >gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax homolog 2 [Homo sapiens] Length = 1210 Score = 39.7 bits (91), Expect = 0.003 Identities = 36/130 (27%), Positives = 51/130 (39%), Gaps = 15/130 (11%) Query: 134 PASAFQKAPEPLGPADQSELGPE-----------QLEAEVGESSDEEPVESRAQRLRRTG 182 P SA Q PEP+ A S E + E+ +S + EP+E+ A Sbjct: 450 PPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPT 509 Query: 183 LQKVQSLRRALSGRKGPAAPP--PTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDT 240 K Q L L+ PAAPP P +PPR P + + +P PP+ + Sbjct: 510 TNKWQ-LDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDP-PPKSS 567 Query: 241 EEDPGRPGAA 250 + P P A Sbjct: 568 SKAPRAPPEA 577 >gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens] Length = 955 Score = 39.7 bits (91), Expect = 0.003 Identities = 34/97 (35%), Positives = 39/97 (40%), Gaps = 12/97 (12%) Query: 165 SSDEEPVESRAQRLRRTGLQKVQSLRRALSGRKGP--------AAPPPTPVKPPRLGPGR 216 +S PV Q L RT L K Q+L + +G GP A P P PRL PG Sbjct: 789 ASPSRPVLHLLQLLLRTNLMKTQTLPTSPAGAHGPHSLALGLTATFPGEPGASPRLSPGP 848 Query: 217 SAEAQPEAQPALEPTLEPEPPQDTEEDPGRPGAAEEA 253 S P P L P P PQ P R +A A Sbjct: 849 ST---PPGAPTL-PLASPGAPQPPPVTPERSFSASGA 881 >gi|85815829 SH3-domain binding protein 1 [Homo sapiens] Length = 701 Score = 39.7 bits (91), Expect = 0.003 Identities = 42/152 (27%), Positives = 58/152 (38%), Gaps = 27/152 (17%) Query: 134 PASAFQKAPEP-LGPA-----DQSELGPEQLEAEVGESSDEE--PVESRAQRLRRTGLQK 185 PA A AP P L A +SE+ P +V S E PVE A+R +R + Sbjct: 513 PAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARRTKRPAPAR 572 Query: 186 VQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPE-------AQPALEPTLEPEPPQ 238 +SG + + PP P PP G + +A P P + P L P PPQ Sbjct: 573 PTMPPPQVSGSR---SSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQ 629 Query: 239 DTEE---------DPGRPGAAEEALLQMESVA 261 P PG A + + + + A Sbjct: 630 PARRQSRRSPASPSPASPGPASPSPVSLSNPA 661 >gi|41322923 plectin 1 isoform 11 [Homo sapiens] Length = 4547 Score = 39.3 bits (90), Expect = 0.003 Identities = 56/238 (23%), Positives = 92/238 (38%), Gaps = 35/238 (14%) Query: 27 TLLEKLASMLETLRERQGGLARRQGGLAGSVRRIQSGLGA---LSRSHDTTSNTLAQLLA 83 TL K + LE R+RQ A + + R+Q L A +R + +L A Sbjct: 1958 TLRSKEQAELEAARQRQLA-AEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKA 2016 Query: 84 KAERVSSHANAAQERAVRRAAQVQRLEANHGLLVARGKLHVLLFKEEGEVPASAFQKAPE 143 K E A++ + R+ Q EA L A K H +++ + Q+ Sbjct: 2017 KVEEARRLRERAEQESARQLQLAQ--EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQ--- 2071 Query: 144 PLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRTGLQKVQSLRRALSGRKGPAAPP 203 +QS L + EAE + EE E+R Q R + QS R+ + Sbjct: 2072 -----EQSVLDQLRGEAEAARRAAEEAEEARVQAER----EAAQSRRQVEEAER------ 2116 Query: 204 PTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDTEEDPGRPGAAEEALLQMESVA 261 + A+A+ +AQ A E + ++ E++ R AE+A L+ + A Sbjct: 2117 ------LKQSAEEQAQARAQAQAAAE-----KLRKEAEQEAARRAQAEQAALRQKQAA 2163 Score = 33.9 bits (76), Expect = 0.15 Identities = 52/211 (24%), Positives = 71/211 (33%), Gaps = 18/211 (8%) Query: 57 VRRIQSGLGALSRSHDTTSNTLAQLLAKAERVSSHANAAQERAVRRAAQVQRLEANHGLL 116 +R ++ L A R L L A+AE + AQE A R QVQ Sbjct: 1454 IRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQA 1513 Query: 117 VARGKLHVLLFKEEGEVPASAFQKAPEPLGPADQSELGPEQLEAE------VGESSDEEP 170 V E A Q E A+++E Q E E V + + Sbjct: 1514 EVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS 1573 Query: 171 VESRAQRLRRTGLQKVQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEP 230 E+ Q R + +K L R+L V R R A+ Q EA+ A E Sbjct: 1574 AEAELQSKRASFAEKTAQLERSLQEEH-------VAVAQLREEAERRAQQQAEAERARE- 1625 Query: 231 TLEPEPPQDTEEDPGRPGAAEEALLQMESVA 261 E ++ E + A LQ E VA Sbjct: 1626 ----EAERELERWQLKANEALRLRLQAEEVA 1652 Score = 28.1 bits (61), Expect = 8.1 Identities = 40/148 (27%), Positives = 50/148 (33%), Gaps = 29/148 (19%) Query: 48 RRQGGLAGSVRRIQSGLGALSRSHDTTSNTLAQLLAKAERVSSHANAAQERAVRRAAQVQ 107 RRQ VRR Q L L + LA E R Q+Q Sbjct: 2557 RRQHEAEEGVRRKQEELQQLEQQRRQQEELLA-----------------EENQRLREQLQ 2599 Query: 108 RLEANHGLLVARGKLHVLLFKEEGEVPASAFQKAPEPLGPADQSELGPEQLEAEVGESSD 167 LE H +A + EV AS Q A P + L EAE S D Sbjct: 2600 LLEEQHRAALAHSE----------EVTAS--QVAATKTLPNGRDALDGPAAEAEPEHSFD 2647 Query: 168 EEPVESRAQRLRRTGLQKVQSLRRALSG 195 + AQRL+ G+ + L+R G Sbjct: 2648 GLRRKVSAQRLQEAGILSAEELQRLAQG 2675 >gi|41322914 plectin 1 isoform 10 [Homo sapiens] Length = 4551 Score = 39.3 bits (90), Expect = 0.003 Identities = 56/238 (23%), Positives = 92/238 (38%), Gaps = 35/238 (14%) Query: 27 TLLEKLASMLETLRERQGGLARRQGGLAGSVRRIQSGLGA---LSRSHDTTSNTLAQLLA 83 TL K + LE R+RQ A + + R+Q L A +R + +L A Sbjct: 1962 TLRSKEQAELEAARQRQLA-AEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKA 2020 Query: 84 KAERVSSHANAAQERAVRRAAQVQRLEANHGLLVARGKLHVLLFKEEGEVPASAFQKAPE 143 K E A++ + R+ Q EA L A K H +++ + Q+ Sbjct: 2021 KVEEARRLRERAEQESARQLQLAQ--EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQ--- 2075 Query: 144 PLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRTGLQKVQSLRRALSGRKGPAAPP 203 +QS L + EAE + EE E+R Q R + QS R+ + Sbjct: 2076 -----EQSVLDQLRGEAEAARRAAEEAEEARVQAER----EAAQSRRQVEEAER------ 2120 Query: 204 PTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDTEEDPGRPGAAEEALLQMESVA 261 + A+A+ +AQ A E + ++ E++ R AE+A L+ + A Sbjct: 2121 ------LKQSAEEQAQARAQAQAAAE-----KLRKEAEQEAARRAQAEQAALRQKQAA 2167 Score = 33.9 bits (76), Expect = 0.15 Identities = 52/211 (24%), Positives = 71/211 (33%), Gaps = 18/211 (8%) Query: 57 VRRIQSGLGALSRSHDTTSNTLAQLLAKAERVSSHANAAQERAVRRAAQVQRLEANHGLL 116 +R ++ L A R L L A+AE + AQE A R QVQ Sbjct: 1458 IRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQA 1517 Query: 117 VARGKLHVLLFKEEGEVPASAFQKAPEPLGPADQSELGPEQLEAE------VGESSDEEP 170 V E A Q E A+++E Q E E V + + Sbjct: 1518 EVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS 1577 Query: 171 VESRAQRLRRTGLQKVQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEP 230 E+ Q R + +K L R+L V R R A+ Q EA+ A E Sbjct: 1578 AEAELQSKRASFAEKTAQLERSLQEEH-------VAVAQLREEAERRAQQQAEAERARE- 1629 Query: 231 TLEPEPPQDTEEDPGRPGAAEEALLQMESVA 261 E ++ E + A LQ E VA Sbjct: 1630 ----EAERELERWQLKANEALRLRLQAEEVA 1656 Score = 28.1 bits (61), Expect = 8.1 Identities = 40/148 (27%), Positives = 50/148 (33%), Gaps = 29/148 (19%) Query: 48 RRQGGLAGSVRRIQSGLGALSRSHDTTSNTLAQLLAKAERVSSHANAAQERAVRRAAQVQ 107 RRQ VRR Q L L + LA E R Q+Q Sbjct: 2561 RRQHEAEEGVRRKQEELQQLEQQRRQQEELLA-----------------EENQRLREQLQ 2603 Query: 108 RLEANHGLLVARGKLHVLLFKEEGEVPASAFQKAPEPLGPADQSELGPEQLEAEVGESSD 167 LE H +A + EV AS Q A P + L EAE S D Sbjct: 2604 LLEEQHRAALAHSE----------EVTAS--QVAATKTLPNGRDALDGPAAEAEPEHSFD 2651 Query: 168 EEPVESRAQRLRRTGLQKVQSLRRALSG 195 + AQRL+ G+ + L+R G Sbjct: 2652 GLRRKVSAQRLQEAGILSAEELQRLAQG 2679 >gi|41322919 plectin 1 isoform 8 [Homo sapiens] Length = 4547 Score = 39.3 bits (90), Expect = 0.003 Identities = 56/238 (23%), Positives = 92/238 (38%), Gaps = 35/238 (14%) Query: 27 TLLEKLASMLETLRERQGGLARRQGGLAGSVRRIQSGLGA---LSRSHDTTSNTLAQLLA 83 TL K + LE R+RQ A + + R+Q L A +R + +L A Sbjct: 1958 TLRSKEQAELEAARQRQLA-AEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKA 2016 Query: 84 KAERVSSHANAAQERAVRRAAQVQRLEANHGLLVARGKLHVLLFKEEGEVPASAFQKAPE 143 K E A++ + R+ Q EA L A K H +++ + Q+ Sbjct: 2017 KVEEARRLRERAEQESARQLQLAQ--EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQ--- 2071 Query: 144 PLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRTGLQKVQSLRRALSGRKGPAAPP 203 +QS L + EAE + EE E+R Q R + QS R+ + Sbjct: 2072 -----EQSVLDQLRGEAEAARRAAEEAEEARVQAER----EAAQSRRQVEEAER------ 2116 Query: 204 PTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDTEEDPGRPGAAEEALLQMESVA 261 + A+A+ +AQ A E + ++ E++ R AE+A L+ + A Sbjct: 2117 ------LKQSAEEQAQARAQAQAAAE-----KLRKEAEQEAARRAQAEQAALRQKQAA 2163 Score = 33.9 bits (76), Expect = 0.15 Identities = 52/211 (24%), Positives = 71/211 (33%), Gaps = 18/211 (8%) Query: 57 VRRIQSGLGALSRSHDTTSNTLAQLLAKAERVSSHANAAQERAVRRAAQVQRLEANHGLL 116 +R ++ L A R L L A+AE + AQE A R QVQ Sbjct: 1454 IRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQA 1513 Query: 117 VARGKLHVLLFKEEGEVPASAFQKAPEPLGPADQSELGPEQLEAE------VGESSDEEP 170 V E A Q E A+++E Q E E V + + Sbjct: 1514 EVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS 1573 Query: 171 VESRAQRLRRTGLQKVQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEP 230 E+ Q R + +K L R+L V R R A+ Q EA+ A E Sbjct: 1574 AEAELQSKRASFAEKTAQLERSLQEEH-------VAVAQLREEAERRAQQQAEAERARE- 1625 Query: 231 TLEPEPPQDTEEDPGRPGAAEEALLQMESVA 261 E ++ E + A LQ E VA Sbjct: 1626 ----EAERELERWQLKANEALRLRLQAEEVA 1652 Score = 28.1 bits (61), Expect = 8.1 Identities = 40/148 (27%), Positives = 50/148 (33%), Gaps = 29/148 (19%) Query: 48 RRQGGLAGSVRRIQSGLGALSRSHDTTSNTLAQLLAKAERVSSHANAAQERAVRRAAQVQ 107 RRQ VRR Q L L + LA E R Q+Q Sbjct: 2557 RRQHEAEEGVRRKQEELQQLEQQRRQQEELLA-----------------EENQRLREQLQ 2599 Query: 108 RLEANHGLLVARGKLHVLLFKEEGEVPASAFQKAPEPLGPADQSELGPEQLEAEVGESSD 167 LE H +A + EV AS Q A P + L EAE S D Sbjct: 2600 LLEEQHRAALAHSE----------EVTAS--QVAATKTLPNGRDALDGPAAEAEPEHSFD 2647 Query: 168 EEPVESRAQRLRRTGLQKVQSLRRALSG 195 + AQRL+ G+ + L+R G Sbjct: 2648 GLRRKVSAQRLQEAGILSAEELQRLAQG 2675 >gi|41322910 plectin 1 isoform 7 [Homo sapiens] Length = 4515 Score = 39.3 bits (90), Expect = 0.003 Identities = 56/238 (23%), Positives = 92/238 (38%), Gaps = 35/238 (14%) Query: 27 TLLEKLASMLETLRERQGGLARRQGGLAGSVRRIQSGLGA---LSRSHDTTSNTLAQLLA 83 TL K + LE R+RQ A + + R+Q L A +R + +L A Sbjct: 1926 TLRSKEQAELEAARQRQLA-AEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKA 1984 Query: 84 KAERVSSHANAAQERAVRRAAQVQRLEANHGLLVARGKLHVLLFKEEGEVPASAFQKAPE 143 K E A++ + R+ Q EA L A K H +++ + Q+ Sbjct: 1985 KVEEARRLRERAEQESARQLQLAQ--EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQ--- 2039 Query: 144 PLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRTGLQKVQSLRRALSGRKGPAAPP 203 +QS L + EAE + EE E+R Q R + QS R+ + Sbjct: 2040 -----EQSVLDQLRGEAEAARRAAEEAEEARVQAER----EAAQSRRQVEEAER------ 2084 Query: 204 PTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDTEEDPGRPGAAEEALLQMESVA 261 + A+A+ +AQ A E + ++ E++ R AE+A L+ + A Sbjct: 2085 ------LKQSAEEQAQARAQAQAAAE-----KLRKEAEQEAARRAQAEQAALRQKQAA 2131 Score = 33.9 bits (76), Expect = 0.15 Identities = 52/211 (24%), Positives = 71/211 (33%), Gaps = 18/211 (8%) Query: 57 VRRIQSGLGALSRSHDTTSNTLAQLLAKAERVSSHANAAQERAVRRAAQVQRLEANHGLL 116 +R ++ L A R L L A+AE + AQE A R QVQ Sbjct: 1422 IRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQA 1481 Query: 117 VARGKLHVLLFKEEGEVPASAFQKAPEPLGPADQSELGPEQLEAE------VGESSDEEP 170 V E A Q E A+++E Q E E V + + Sbjct: 1482 EVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS 1541 Query: 171 VESRAQRLRRTGLQKVQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEP 230 E+ Q R + +K L R+L V R R A+ Q EA+ A E Sbjct: 1542 AEAELQSKRASFAEKTAQLERSLQEEH-------VAVAQLREEAERRAQQQAEAERARE- 1593 Query: 231 TLEPEPPQDTEEDPGRPGAAEEALLQMESVA 261 E ++ E + A LQ E VA Sbjct: 1594 ----EAERELERWQLKANEALRLRLQAEEVA 1620 Score = 28.1 bits (61), Expect = 8.1 Identities = 40/148 (27%), Positives = 50/148 (33%), Gaps = 29/148 (19%) Query: 48 RRQGGLAGSVRRIQSGLGALSRSHDTTSNTLAQLLAKAERVSSHANAAQERAVRRAAQVQ 107 RRQ VRR Q L L + LA E R Q+Q Sbjct: 2525 RRQHEAEEGVRRKQEELQQLEQQRRQQEELLA-----------------EENQRLREQLQ 2567 Query: 108 RLEANHGLLVARGKLHVLLFKEEGEVPASAFQKAPEPLGPADQSELGPEQLEAEVGESSD 167 LE H +A + EV AS Q A P + L EAE S D Sbjct: 2568 LLEEQHRAALAHSE----------EVTAS--QVAATKTLPNGRDALDGPAAEAEPEHSFD 2615 Query: 168 EEPVESRAQRLRRTGLQKVQSLRRALSG 195 + AQRL+ G+ + L+R G Sbjct: 2616 GLRRKVSAQRLQEAGILSAEELQRLAQG 2643 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.127 0.349 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,818,659 Number of Sequences: 37866 Number of extensions: 684980 Number of successful extensions: 9788 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 246 Number of HSP's successfully gapped in prelim test: 777 Number of HSP's that attempted gapping in prelim test: 6543 Number of HSP's gapped (non-prelim): 3431 length of query: 261 length of database: 18,247,518 effective HSP length: 100 effective length of query: 161 effective length of database: 14,460,918 effective search space: 2328207798 effective search space used: 2328207798 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.